Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000004-TA|BGIBMGA000004-PA|IPR001128|Cytochrome P450,
IPR002401|E-class P450, group I
(311 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 174 4e-43
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 174 4e-43
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 174 4e-43
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 174 4e-43
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 144 3e-34
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 143 8e-34
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 143 8e-34
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 142 1e-33
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 142 1e-33
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 142 1e-33
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 142 1e-33
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 142 1e-33
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 139 1e-32
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 139 1e-32
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 137 4e-32
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 137 4e-32
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 137 4e-32
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 137 4e-32
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 137 4e-32
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 137 4e-32
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 137 4e-32
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 136 9e-32
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 136 9e-32
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 136 9e-32
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 136 9e-32
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 136 9e-32
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 136 9e-32
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 136 9e-32
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 136 9e-32
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 136 9e-32
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 132 1e-30
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 131 3e-30
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 128 2e-29
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 121 4e-27
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 121 4e-27
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 121 4e-27
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 121 4e-27
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 121 4e-27
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 121 4e-27
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 121 4e-27
AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 121 4e-27
AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 121 4e-27
AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 121 4e-27
AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 121 4e-27
AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 121 4e-27
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 121 4e-27
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 121 4e-27
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 120 5e-27
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 120 5e-27
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 120 5e-27
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 120 9e-27
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 119 2e-26
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 118 3e-26
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 117 6e-26
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 117 6e-26
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 117 6e-26
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 117 6e-26
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 117 6e-26
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 115 2e-25
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 115 2e-25
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 115 2e-25
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 114 3e-25
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 114 3e-25
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 114 3e-25
AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, famil... 114 4e-25
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 114 4e-25
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 113 6e-25
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 109 2e-23
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 109 2e-23
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 109 2e-23
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 109 2e-23
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 106 9e-23
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 102 2e-21
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 102 2e-21
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 102 2e-21
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 102 2e-21
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 102 2e-21
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 102 2e-21
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 102 2e-21
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 102 2e-21
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 102 2e-21
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 102 2e-21
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 101 2e-21
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 101 2e-21
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 101 2e-21
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 101 4e-21
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 101 4e-21
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 100 7e-21
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 99 2e-20
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 99 2e-20
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 99 2e-20
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 99 2e-20
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 96 1e-19
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 95 3e-19
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 95 3e-19
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 95 4e-19
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 95 4e-19
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 95 4e-19
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 95 4e-19
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 94 5e-19
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 94 5e-19
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 94 5e-19
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 94 5e-19
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 94 5e-19
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 94 5e-19
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 94 5e-19
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 94 5e-19
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 94 5e-19
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 94 5e-19
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 94 5e-19
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 94 5e-19
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 94 5e-19
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 94 5e-19
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 94 5e-19
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 94 5e-19
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 94 5e-19
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 94 5e-19
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 94 6e-19
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 93 9e-19
AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 93 9e-19
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 93 9e-19
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 93 9e-19
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 93 1e-18
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 93 1e-18
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 93 1e-18
BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein. 93 1e-18
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 92 2e-18
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 92 2e-18
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 92 2e-18
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 92 2e-18
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 92 2e-18
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 92 2e-18
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 91 3e-18
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 91 3e-18
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 91 3e-18
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 91 3e-18
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 91 3e-18
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 91 3e-18
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 91 3e-18
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 91 3e-18
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 91 6e-18
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 91 6e-18
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 91 6e-18
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 89 1e-17
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 89 2e-17
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 88 3e-17
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 88 3e-17
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 87 7e-17
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 87 1e-16
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 86 2e-16
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 86 2e-16
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 85 2e-16
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 85 2e-16
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 85 2e-16
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 85 2e-16
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 85 2e-16
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 85 2e-16
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 85 2e-16
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 85 2e-16
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 85 2e-16
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 85 2e-16
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 85 2e-16
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 85 3e-16
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 85 3e-16
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 84 7e-16
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 83 9e-16
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 83 9e-16
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 83 9e-16
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 83 9e-16
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 83 9e-16
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 83 9e-16
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 83 9e-16
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 83 1e-15
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 83 1e-15
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 83 1e-15
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 83 1e-15
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 83 1e-15
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 83 1e-15
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 83 1e-15
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 83 1e-15
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 83 1e-15
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 83 1e-15
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 83 2e-15
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 83 2e-15
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 83 2e-15
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 83 2e-15
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 83 2e-15
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 83 2e-15
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 83 2e-15
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 82 2e-15
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 82 2e-15
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 82 2e-15
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 82 2e-15
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 82 2e-15
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 82 2e-15
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 82 2e-15
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 82 2e-15
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 81 4e-15
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 81 5e-15
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 81 5e-15
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 81 5e-15
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 81 5e-15
D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV prot... 81 6e-15
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 81 6e-15
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 80 1e-14
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 80 1e-14
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 80 1e-14
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 80 1e-14
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 80 1e-14
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 80 1e-14
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 80 1e-14
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 80 1e-14
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 80 1e-14
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 80 1e-14
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 80 1e-14
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 80 1e-14
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 80 1e-14
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 79 1e-14
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 79 3e-14
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 79 3e-14
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 79 3e-14
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 79 3e-14
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 79 3e-14
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 79 3e-14
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 78 3e-14
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 78 3e-14
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 78 3e-14
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 78 3e-14
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 78 3e-14
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 78 3e-14
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 78 3e-14
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 78 3e-14
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 78 3e-14
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 78 3e-14
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 78 5e-14
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 77 6e-14
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 77 6e-14
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 77 6e-14
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 77 6e-14
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 77 6e-14
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 77 6e-14
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 77 6e-14
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 77 6e-14
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 77 6e-14
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 77 6e-14
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 77 6e-14
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 77 6e-14
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 77 6e-14
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 77 1e-13
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 77 1e-13
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 77 1e-13
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 77 1e-13
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 77 1e-13
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 77 1e-13
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 77 1e-13
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 76 1e-13
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 76 1e-13
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 76 1e-13
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 76 2e-13
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 76 2e-13
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 75 2e-13
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 75 2e-13
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 75 2e-13
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 75 2e-13
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 75 2e-13
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 75 2e-13
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 75 2e-13
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 75 4e-13
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 74 6e-13
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 74 6e-13
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 74 6e-13
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 74 6e-13
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 74 6e-13
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 74 6e-13
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 74 6e-13
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 74 6e-13
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 74 6e-13
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 74 6e-13
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 74 6e-13
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 74 6e-13
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 74 6e-13
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 74 7e-13
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 74 7e-13
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 73 1e-12
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 73 1e-12
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 73 1e-12
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 73 1e-12
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 73 1e-12
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 73 1e-12
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 73 1e-12
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 73 1e-12
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 73 1e-12
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 73 1e-12
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 73 1e-12
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 73 1e-12
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 73 1e-12
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 73 2e-12
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 73 2e-12
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 73 2e-12
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 73 2e-12
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 72 2e-12
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 72 3e-12
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 71 4e-12
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 70 9e-12
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 70 9e-12
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 70 9e-12
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 70 9e-12
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 70 9e-12
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 70 9e-12
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 70 9e-12
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 70 9e-12
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 70 9e-12
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 70 1e-11
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 70 1e-11
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 70 1e-11
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 70 1e-11
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 70 1e-11
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 70 1e-11
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 70 1e-11
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 70 1e-11
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 69 2e-11
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 69 2e-11
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 69 2e-11
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 69 2e-11
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 69 2e-11
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 69 3e-11
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 67 6e-11
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 67 9e-11
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 66 2e-10
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 65 3e-10
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 65 3e-10
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 65 3e-10
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 65 3e-10
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 65 3e-10
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 65 3e-10
BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 65 3e-10
BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 65 3e-10
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 65 3e-10
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 65 3e-10
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 65 3e-10
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 65 3e-10
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 65 3e-10
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 65 3e-10
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 65 3e-10
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 65 3e-10
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 65 3e-10
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 65 3e-10
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 65 3e-10
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 65 3e-10
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 65 3e-10
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 65 3e-10
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 64 8e-10
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 64 8e-10
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 64 8e-10
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 63 1e-09
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 63 1e-09
AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family... 63 1e-09
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 62 2e-09
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 62 2e-09
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 62 2e-09
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 62 3e-09
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 62 3e-09
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 62 3e-09
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 62 3e-09
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 60 7e-09
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 60 1e-08
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 60 1e-08
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 55 4e-07
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 54 5e-07
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 54 5e-07
AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 54 5e-07
AC011737-1|AAX88915.1| 382|Homo sapiens unknown protein. 54 5e-07
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 54 8e-07
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 52 3e-06
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 52 3e-06
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 52 3e-06
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 52 3e-06
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 51 6e-06
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 50 8e-06
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 50 1e-05
M29873-1|AAA52143.1| 377|Homo sapiens CYP2B protein. 50 1e-05
BC041174-1|AAH41174.1| 377|Homo sapiens CYP2B7P1 protein protein. 50 1e-05
BC056258-1|AAH56258.1| 359|Homo sapiens CYP19A1 protein protein. 48 6e-05
BC020767-1|AAH20767.1| 360|Homo sapiens Unknown (protein for IM... 48 6e-05
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 46 2e-04
AK097373-1|BAC05026.1| 340|Homo sapiens protein ( Homo sapiens ... 46 2e-04
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 44 7e-04
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 44 7e-04
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 44 0.001
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 42 0.002
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 42 0.002
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 42 0.003
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 42 0.003
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 40 0.015
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 39 0.020
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 39 0.020
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 39 0.026
AC005336-2|AAC27731.1| 93|Homo sapiens F20191_1, partial CDS p... 38 0.034
BC041839-1|AAH41839.1| 51|Homo sapiens CYP4V2 protein protein. 36 0.24
BC128535-1|AAI28536.1| 143|Homo sapiens LOC283480 protein protein. 34 0.56
AY064484-1|AAL57719.1| 295|Homo sapiens truncated cytochrome P4... 33 1.3
AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 31 3.9
AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 31 3.9
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 31 5.2
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 31 5.2
AY691428-1|AAV80764.1| 360|Homo sapiens WIPI-4 protein. 30 9.0
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 174 bits (423), Expect = 4e-43
Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 18/324 (5%)
Query: 6 ETALGIKMEDHSAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVL 65
ETA+G + S + +Y +A++ + ++ R + WL D Y K + +K+L
Sbjct: 202 ETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKIL 261
Query: 66 HNMSNTALQQRKSVFLQEHDAASD----KPT--------DIILETC---GGAFSDKDVRE 110
H +N+ + +R + D D P+ D++L G S +D+RE
Sbjct: 262 HTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIRE 321
Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
EVD +F GHDT + + +L LLGS+P+VQ KV +E+ V G ++R T ED +L YL
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
E V+KE++R++P P+ AR + ++ Y G+ +++ + +H+ + + ++F+P
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQP 441
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
ER+ E A P + FS G R+CIG+ +A+M KT LS +LR + + S+ E L
Sbjct: 442 ERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 501
Query: 290 EA--ILRPHRGHYIAIERRSKDDK 311
E ILRP G +I ++RR+ D++
Sbjct: 502 EGQLILRPSNGIWIKLKRRNADER 525
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 174 bits (423), Expect = 4e-43
Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 18/324 (5%)
Query: 6 ETALGIKMEDHSAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVL 65
ETA+G + S + +Y +A++ + ++ R + WL D Y K + +K+L
Sbjct: 202 ETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKIL 261
Query: 66 HNMSNTALQQRKSVFLQEHDAASD----KPT--------DIILETC---GGAFSDKDVRE 110
H +N+ + +R + D D P+ D++L G S +D+RE
Sbjct: 262 HTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIRE 321
Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
EVD +F GHDT + + +L LLGS+P+VQ KV +E+ V G ++R T ED +L YL
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
E V+KE++R++P P+ AR + ++ Y G+ +++ + +H+ + + ++F+P
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQP 441
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
ER+ E A P + FS G R+CIG+ +A+M KT LS +LR + + S+ E L
Sbjct: 442 ERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 501
Query: 290 EA--ILRPHRGHYIAIERRSKDDK 311
E ILRP G +I ++RR+ D++
Sbjct: 502 EGQLILRPSNGIWIKLKRRNADER 525
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 174 bits (423), Expect = 4e-43
Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 18/324 (5%)
Query: 6 ETALGIKMEDHSAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVL 65
ETA+G + S + +Y +A++ + ++ R + WL D Y K + +K+L
Sbjct: 180 ETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKIL 239
Query: 66 HNMSNTALQQRKSVFLQEHDAASD----KPT--------DIILETC---GGAFSDKDVRE 110
H +N+ + +R + D D P+ D++L G S +D+RE
Sbjct: 240 HTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIRE 299
Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
EVD +F GHDT + + +L LLGS+P+VQ KV +E+ V G ++R T ED +L YL
Sbjct: 300 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 359
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
E V+KE++R++P P+ AR + ++ Y G+ +++ + +H+ + + ++F+P
Sbjct: 360 ECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQP 419
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
ER+ E A P + FS G R+CIG+ +A+M KT LS +LR + + S+ E L
Sbjct: 420 ERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 479
Query: 290 EA--ILRPHRGHYIAIERRSKDDK 311
E ILRP G +I ++RR+ D++
Sbjct: 480 EGQLILRPSNGIWIKLKRRNADER 503
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 174 bits (423), Expect = 4e-43
Identities = 103/324 (31%), Positives = 175/324 (54%), Gaps = 18/324 (5%)
Query: 6 ETALGIKMEDHSAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVL 65
ETA+G + S + +Y +A++ + ++ R + WL D Y K + +K+L
Sbjct: 202 ETAMGKNIGAQSNDDSEYVRAVYRMSEMIFRRIKMPWLWLDLWYLMFKEGWEHKKSLKIL 261
Query: 66 HNMSNTALQQRKSVFLQEHDAASD----KPT--------DIILETC---GGAFSDKDVRE 110
H +N+ + +R + D D P+ D++L G S +D+RE
Sbjct: 262 HTFTNSVIAERANEMNANEDCRGDGRGSAPSKNKRRAFLDLLLSVTDDEGNRLSHEDIRE 321
Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
EVD +F GHDT + + +L LLGS+P+VQ KV +E+ V G ++R T ED +L YL
Sbjct: 322 EVDTFMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYL 381
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
E V+KE++R++P P+ AR + ++ Y G+ +++ + +H+ + + ++F+P
Sbjct: 382 ECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQP 441
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
ER+ E A P + FS G R+CIG+ +A+M KT LS +LR + + S+ E L
Sbjct: 442 ERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKREELGL 501
Query: 290 EA--ILRPHRGHYIAIERRSKDDK 311
E ILRP G +I ++RR+ D++
Sbjct: 502 EGQLILRPSNGIWIKLKRRNADER 525
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 144 bits (350), Expect = 3e-34
Identities = 90/298 (30%), Positives = 158/298 (53%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++++R + LH DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++VL+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASVLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R+ ++ L + P G ++ ++G H + D + + P R+ E P F
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+RV D T+ K E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 143 bits (346), Expect = 8e-34
Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++++R + LH DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R+ ++ L + P G ++ ++G H + D + + P R+ E P F
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+RV D T+ K E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 143 bits (346), Expect = 8e-34
Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++++R + LH DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R+ ++ L + P G ++ ++G H + D + + P R+ E P F
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+RV D T+ K E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 142 bits (344), Expect = 1e-33
Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++++R + LH DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R+ ++ L + P G ++ ++G H + D + + P R+ E P F
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+RV D T+ K E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 142 bits (344), Expect = 1e-33
Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++++R + LH DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R+ ++ L + P G ++ ++G H + D + + P R+ E P F
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+RV D T+ K E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 142 bits (344), Expect = 1e-33
Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++++R + LH DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R+ ++ L + P G ++ ++G H + D + + P R+ E P F
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+RV D T+ K E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 142 bits (344), Expect = 1e-33
Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++++R + LH DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R+ ++ L + P G ++ ++G H + D + + P R+ E P F
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+RV D T+ K E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 142 bits (344), Expect = 1e-33
Identities = 89/298 (29%), Positives = 157/298 (52%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++++R + LH DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVSKRHHEILLHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R+ ++ L + P G ++ ++G H + D + + P R+ E P F
Sbjct: 400 RHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+RV D T+ K E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 139 bits (336), Expect = 1e-32
Identities = 87/299 (29%), Positives = 158/299 (52%), Gaps = 17/299 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++T+R Q+ L+ DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D +L +L +KES+R++P P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
R ++ L + P G ++ ++G H + D + + P R+ + + + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458
Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L L R+RV D T+ K E +LR G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 139 bits (336), Expect = 1e-32
Identities = 87/299 (29%), Positives = 158/299 (52%), Gaps = 17/299 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++T+R Q+ L+ DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D +L +L +KES+R++P P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
R ++ L + P G ++ ++G H + D + + P R+ + + + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458
Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L L R+RV D T+ K E +LR G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRRKPELVLRAEGGIWLRVE 517
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 137 bits (332), Expect = 4e-32
Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)
Query: 17 SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
++ + Y +A+ ++ ++ R H D ++ + R ++ +VL+ ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265
Query: 77 KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
K LQ + P DI+L + G +FSD DV EV + AGHDT++
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324
Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
++ L L +P+ Q++ EVR +LGD +T + + Y +KE+ R+ P P
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383
Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
I+R + + T PAG +L +WG+H + + F P R+ E + P
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443
Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
+ FS G R+CIG+ +AM+ +K T++ +L +RV+ D T L F IL+P G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503
Query: 304 ERRSK 308
++ S+
Sbjct: 504 KKLSE 508
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 137 bits (332), Expect = 4e-32
Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)
Query: 17 SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
++ + Y +A+ ++ ++ R H D ++ + R ++ +VL+ ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265
Query: 77 KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
K LQ + P DI+L + G +FSD DV EV + AGHDT++
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324
Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
++ L L +P+ Q++ EVR +LGD +T + + Y +KE+ R+ P P
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383
Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
I+R + + T PAG +L +WG+H + + F P R+ E + P
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443
Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
+ FS G R+CIG+ +AM+ +K T++ +L +RV+ D T L F IL+P G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503
Query: 304 ERRSK 308
++ S+
Sbjct: 504 KKLSE 508
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 137 bits (332), Expect = 4e-32
Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)
Query: 17 SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
++ + Y +A+ ++ ++ R H D ++ + R ++ +VL+ ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265
Query: 77 KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
K LQ + P DI+L + G +FSD DV EV + AGHDT++
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324
Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
++ L L +P+ Q++ EVR +LGD +T + + Y +KE+ R+ P P
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383
Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
I+R + + T PAG +L +WG+H + + F P R+ E + P
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443
Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
+ FS G R+CIG+ +AM+ +K T++ +L +RV+ D T L F IL+P G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503
Query: 304 ERRSK 308
++ S+
Sbjct: 504 KKLSE 508
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 137 bits (332), Expect = 4e-32
Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)
Query: 17 SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
++ + Y +A+ ++ ++ R H D ++ + R ++ +VL+ ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265
Query: 77 KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
K LQ + P DI+L + G +FSD DV EV + AGHDT++
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324
Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
++ L L +P+ Q++ EVR +LGD +T + + Y +KE+ R+ P P
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383
Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
I+R + + T PAG +L +WG+H + + F P R+ E + P
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443
Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
+ FS G R+CIG+ +AM+ +K T++ +L +RV+ D T L F IL+P G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503
Query: 304 ERRSK 308
++ S+
Sbjct: 504 KKLSE 508
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 137 bits (332), Expect = 4e-32
Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)
Query: 17 SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
++ + Y +A+ ++ ++ R H D ++ + R ++ +VL+ ++T +Q+R
Sbjct: 205 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 264
Query: 77 KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
K LQ + P DI+L + G +FSD DV EV + AGHDT++
Sbjct: 265 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 323
Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
++ L L +P+ Q++ EVR +LGD +T + + Y +KE+ R+ P P
Sbjct: 324 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 382
Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
I+R + + T PAG +L +WG+H + + F P R+ E + P
Sbjct: 383 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 442
Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
+ FS G R+CIG+ +AM+ +K T++ +L +RV+ D T L F IL+P G Y+ +
Sbjct: 443 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 502
Query: 304 ERRSK 308
++ S+
Sbjct: 503 KKLSE 507
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 137 bits (332), Expect = 4e-32
Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)
Query: 17 SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
++ + Y +A+ ++ ++ R H D ++ + R ++ +VL+ ++T +Q+R
Sbjct: 206 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 265
Query: 77 KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
K LQ + P DI+L + G +FSD DV EV + AGHDT++
Sbjct: 266 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 324
Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
++ L L +P+ Q++ EVR +LGD +T + + Y +KE+ R+ P P
Sbjct: 325 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 383
Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
I+R + + T PAG +L +WG+H + + F P R+ E + P
Sbjct: 384 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 443
Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
+ FS G R+CIG+ +AM+ +K T++ +L +RV+ D T L F IL+P G Y+ +
Sbjct: 444 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 503
Query: 304 ERRSK 308
++ S+
Sbjct: 504 KKLSE 508
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 137 bits (332), Expect = 4e-32
Identities = 87/305 (28%), Positives = 154/305 (50%), Gaps = 15/305 (4%)
Query: 17 SAVNQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQR 76
++ + Y +A+ ++ ++ R H D ++ + R ++ +VL+ ++T +Q+R
Sbjct: 141 NSTHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQKLSRVLNQYTDTIIQER 200
Query: 77 KSVFLQEHDAASDKPT-------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTV 126
K LQ + P DI+L + G +FSD DV EV + AGHDT++
Sbjct: 201 KKS-LQAGVKQDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAAS 259
Query: 127 LTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPV 186
++ L L +P+ Q++ EVR +LGD +T + + Y +KE+ R+ P P
Sbjct: 260 ISWILYCLALNPEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPS 318
Query: 187 IARYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSF 244
I+R + + T PAG +L +WG+H + + F P R+ E + P
Sbjct: 319 ISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYA 378
Query: 245 FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAI 303
+ FS G R+CIG+ +AM+ +K T++ +L +RV+ D T L F IL+P G Y+ +
Sbjct: 379 YLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHL 438
Query: 304 ERRSK 308
++ S+
Sbjct: 439 KKLSE 443
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 136 bits (329), Expect = 9e-32
Identities = 86/299 (28%), Positives = 157/299 (52%), Gaps = 17/299 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++T+R Q+ L+ DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D +L +L +KES+R++P P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
R ++ L + P G ++ ++G H + D + + P R+ + + + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458
Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L L +RV D T+ K E +LR G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 136 bits (329), Expect = 9e-32
Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y + ++ A++ +R Q H DF+Y + R + +++H+ ++ +++R+
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279
Query: 82 QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ D A K D I + G A SD+D+R E D +F GHDT ++ L+
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D + +++ +D +L +L +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R ++ L + P G ++ + GVH + D + + P R+ E + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ +L +R D T+ KLE I+R G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 136 bits (329), Expect = 9e-32
Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y + ++ A++ +R Q H DF+Y + R + +++H+ ++ +++R+
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279
Query: 82 QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ D A K D I + G A SD+D+R E D +F GHDT ++ L+
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D + +++ +D +L +L +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R ++ L + P G ++ + GVH + D + + P R+ E + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ +L +R D T+ KLE I+R G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 136 bits (329), Expect = 9e-32
Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y + ++ A++ +R Q H DF+Y + R + +++H+ ++ +++R+
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279
Query: 82 QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ D A K D I + G A SD+D+R E D +F GHDT ++ L+
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D + +++ +D +L +L +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R ++ L + P G ++ + GVH + D + + P R+ E + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ +L +R D T+ KLE I+R G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 136 bits (329), Expect = 9e-32
Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y + ++ A++ +R Q H DF+Y + R + +++H+ ++ +++R+
Sbjct: 154 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 213
Query: 82 QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ D A K D I + G A SD+D+R E D +F GHDT ++ L+
Sbjct: 214 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 273
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D + +++ +D +L +L +KES+R++P AP I+
Sbjct: 274 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 333
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R ++ L + P G ++ + GVH + D + + P R+ E + P F
Sbjct: 334 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 393
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ +L +R D T+ KLE I+R G ++ +E
Sbjct: 394 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 451
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 136 bits (329), Expect = 9e-32
Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y + ++ A++ +R Q H DF+Y + R + +++H+ ++ +++R+
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279
Query: 82 QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ D A K D I + G A SD+D+R E D +F GHDT ++ L+
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D + +++ +D +L +L +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R ++ L + P G ++ + GVH + D + + P R+ E + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ +L +R D T+ KLE I+R G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 136 bits (329), Expect = 9e-32
Identities = 86/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y + ++ A++ +R Q H DF+Y + R + +++H+ ++ +++R+
Sbjct: 220 EYIATILELSALVEKRSQHILQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLP 279
Query: 82 QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ D A K D I + G A SD+D+R E D +F GHDT ++ L+
Sbjct: 280 TQGIDDFFKDKAKSKTLDFIDVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D + +++ +D +L +L +KES+R++P AP I+
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R ++ L + P G ++ + GVH + D + + P R+ E + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ +L +R D T+ KLE I+R G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVE 517
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 136 bits (329), Expect = 9e-32
Identities = 86/299 (28%), Positives = 157/299 (52%), Gaps = 17/299 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++T+R Q+ L+ DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D +L +L +KES+R++P P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
R ++ L + P G ++ ++G H + D + + P R+ + + + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458
Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L L +RV D T+ K E +LR G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 136 bits (329), Expect = 9e-32
Identities = 86/299 (28%), Positives = 157/299 (52%), Gaps = 17/299 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++T+R Q+ L+ DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDDVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D +L +L +KES+R++P P ++
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERWLEAATLPD--PSFF 245
R ++ L + P G ++ ++G H + D + + P R+ + + + P F
Sbjct: 400 RCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVYDPFRF-DPKNIKERSPLAF 458
Query: 246 AGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L L +RV D T+ K E +LR G ++ +E
Sbjct: 459 IPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRRKPELVLRAEGGLWLRVE 517
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 132 bits (320), Expect = 1e-30
Identities = 85/298 (28%), Positives = 153/298 (51%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y A+ ++ A++ +R +F+ + DF+Y T R + +++H+ ++ +Q+R+
Sbjct: 220 EYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLT 279
Query: 82 QEH-----DAASDKPT----DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ A + T D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E +++ +D +L +L LKES+R++P P A
Sbjct: 340 VLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFA 399
Query: 189 RYSDAEVKL-KNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R +V L + P G+ + ++ +H + D + + P R+ E A P F
Sbjct: 400 RGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L R+R+ D + E +LR G ++ +E
Sbjct: 460 PFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVE 517
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 131 bits (316), Expect = 3e-30
Identities = 87/298 (29%), Positives = 149/298 (50%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y A+ ++ A + +R Q+ LH DF+Y T +R + ++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRRTLP 279
Query: 82 QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ + A K D I + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 TQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAER-DVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E ++ +D +L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R + L + P G ++ + G+H + D + + P R+ E P F
Sbjct: 400 RCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L +R+ T+ K E ILR G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVE 517
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 128 bits (310), Expect = 2e-29
Identities = 86/298 (28%), Positives = 148/298 (49%), Gaps = 15/298 (5%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFL 81
+Y A+ ++ A + +R Q+ LH DF+Y T +R + ++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRRTLP 279
Query: 82 QE------HDAASDKPTDII------LETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+ + A K D I + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 TQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAER-DVTKEDYLRLEYLEAVLKESMRMYPVAPVIA 188
L L HP+ Q++ EV+ +L D E ++ +D +L +L +KES+R++P PVI+
Sbjct: 340 VLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVIS 399
Query: 189 RYSDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFA 246
R + L + P G ++ + G+H + D + + P R+ E P F
Sbjct: 400 RCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFI 459
Query: 247 GFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAILRPHRGHYIAIE 304
FS G R+CIG+ +AM MK L+ L +R+ + K E ILR G ++ +E
Sbjct: 460 PFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHIEPRRKPELILRAEGGLWLRVE 517
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 209 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 268
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 328
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 387
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 388 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 447
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 448 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 504
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 194 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 253
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 313
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 372
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 373 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 432
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 433 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 489
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 209 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 268
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 328
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 387
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 388 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 447
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 448 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 504
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 194 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 253
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 313
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 372
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 373 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 432
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 433 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 489
>AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 209 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 268
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 328
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 387
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 388 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 447
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 448 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 504
>AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 209 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 268
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 328
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 387
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 388 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 447
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 448 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 504
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 194 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 253
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 313
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 372
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 373 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 432
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 433 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 489
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 121 bits (291), Expect = 4e-27
Identities = 84/297 (28%), Positives = 145/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT ++ ++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTSGISWF 327
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 328 LYCIALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 120 bits (290), Expect = 5e-27
Identities = 80/297 (26%), Positives = 147/297 (49%), Gaps = 15/297 (5%)
Query: 23 YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
Y A+ ++ A+ R + + DF+Y R+ R Q ++H+ + +Q+R+ Q
Sbjct: 229 YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQ 288
Query: 83 EHDAASDKPT--------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTAL 131
+ A K D++L + G SD+D+R E D +F GHDT S+ ++ L
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWML 348
Query: 132 SLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L +P+ Q+K E++ V+ E ++ +D +L + +KES+R YP +++R
Sbjct: 349 FNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQ 408
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
++KL + P G ++ ++G H + D+ + P R+ + P + F
Sbjct: 409 CTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPF 468
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAIE 304
S G R+CIG+ +AM ++ ++ L R+R+S D T + K E ILR G ++ +E
Sbjct: 469 SAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 120 bits (290), Expect = 5e-27
Identities = 80/297 (26%), Positives = 147/297 (49%), Gaps = 15/297 (5%)
Query: 23 YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
Y A+ ++ A+ R + + DF+Y R+ R Q ++H+ + +Q+R+ Q
Sbjct: 229 YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQ 288
Query: 83 EHDAASDKPT--------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTAL 131
+ A K D++L + G SD+D+R E D +F GHDT S+ ++ L
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWML 348
Query: 132 SLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L +P+ Q+K E++ V+ E ++ +D +L + +KES+R YP +++R
Sbjct: 349 FNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQ 408
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
++KL + P G ++ ++G H + D+ + P R+ + P + F
Sbjct: 409 CTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPF 468
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAIE 304
S G R+CIG+ +AM ++ ++ L R+R+S D T + K E ILR G ++ +E
Sbjct: 469 SAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 120 bits (290), Expect = 5e-27
Identities = 80/297 (26%), Positives = 147/297 (49%), Gaps = 15/297 (5%)
Query: 23 YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
Y A+ ++ A+ R + + DF+Y R+ R Q ++H+ + +Q+R+ Q
Sbjct: 229 YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRQ 288
Query: 83 EHDAASDKPT--------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTAL 131
+ A K D++L + G SD+D+R E D +F GHDT S+ ++ L
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWML 348
Query: 132 SLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L +P+ Q+K E++ V+ E ++ +D +L + +KES+R YP +++R
Sbjct: 349 FNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQ 408
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
++KL + P G ++ ++G H + D+ + P R+ + P + F
Sbjct: 409 CTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPF 468
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAIE 304
S G R+CIG+ +AM ++ ++ L R+R+S D T + K E ILR G ++ +E
Sbjct: 469 SAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 120 bits (288), Expect = 9e-27
Identities = 84/297 (28%), Positives = 144/297 (48%), Gaps = 13/297 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+ Y A+ D+ ++ +R F H DF+Y T R + +V H+ ++ +++RK+
Sbjct: 208 DSSYYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLRACQVAHDHTDQVIRERKAA 267
Query: 80 FLQE--HDAASDKPTDIILETCGGA-------FSDKDVREEVDNIIFAGHDTISTVLTTA 130
E ++ L+ GA SD D+R EVD +F GHDT + ++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFMFEGHDTTTGGISWF 327
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L + +P+ Q + EVR +LGD + +D ++ YL +KES R+YP P + R
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQD-FFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQ 386
Query: 191 SDAEVK-LKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
V + + PAGS + ++ +H++ D + F R+ E A+ P F F
Sbjct: 387 LSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRHPFAFMPF 446
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIE 304
S G R+CIG+ +AM MK + L R+ S D + L K+ + +LR G ++ ++
Sbjct: 447 SAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKMPQLVLRSKNGFHLHLK 503
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 119 bits (286), Expect = 2e-26
Identities = 79/297 (26%), Positives = 147/297 (49%), Gaps = 15/297 (5%)
Query: 23 YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
Y A+ ++ A+ R + + DF+Y R+ R Q ++H+ + +Q+R+ +
Sbjct: 229 YISAIIELSALSVRRQYRLHHYLDFIYYRSADGRRFRQACDMVHHFTTEVIQERRRALRR 288
Query: 83 EHDAASDKPT--------DIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTAL 131
+ A K D++L + G SD+D+R E D +F GHDT S+ ++ L
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLLLARDEDGKELSDEDIRAEADTFMFEGHDTTSSGISWML 348
Query: 132 SLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L +P+ Q+K E++ V+ E ++ +D +L + +KES+R YP +++R
Sbjct: 349 FNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQYPPVTLVSRQ 408
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGF 248
++KL + P G ++ ++G H + D+ + P R+ + P + F
Sbjct: 409 CTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQQRSPLAYVPF 468
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVT-DLEFKLEAILRPHRGHYIAIE 304
S G R+CIG+ +AM ++ ++ L R+R+S D T + K E ILR G ++ +E
Sbjct: 469 SAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRKPELILRTENGLWLKVE 525
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 118 bits (284), Expect = 3e-26
Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 117 bits (281), Expect = 6e-26
Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 117 bits (281), Expect = 6e-26
Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 117 bits (281), Expect = 6e-26
Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 117 bits (281), Expect = 6e-26
Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ +++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLSSLVFCRMRNAFHENDAIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQTEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRLRR 508
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 117 bits (281), Expect = 6e-26
Identities = 80/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 115 bits (277), Expect = 2e-25
Identities = 77/285 (27%), Positives = 138/285 (48%), Gaps = 14/285 (4%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPSRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKLEAIL 293
S G R+CIGK +AM +K + L R+ + D T + + ++
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLV 495
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 115 bits (277), Expect = 2e-25
Identities = 80/298 (26%), Positives = 143/298 (47%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRTPIPMARLVLKSKNGIHLRLRR 508
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 115 bits (277), Expect = 2e-25
Identities = 79/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R++P P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 114 bits (275), Expect = 3e-25
Identities = 64/208 (30%), Positives = 116/208 (55%), Gaps = 4/208 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ L L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PVA + R +V++ P GS ++ + +H +
Sbjct: 348 DAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKY 407
Query: 222 GADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS-S 280
+ ++FRPER+ + DP + F TG R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467
Query: 281 DVTDLEFKL--EAILRPHRGHYIAIERR 306
T + KL + +L+P + + ++ R
Sbjct: 468 KETQIPLKLDTQGLLQPEKPIVLKVDSR 495
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 114 bits (275), Expect = 3e-25
Identities = 64/208 (30%), Positives = 116/208 (55%), Gaps = 4/208 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ L L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PVA + R +V++ P GS ++ + +H +
Sbjct: 348 DAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKY 407
Query: 222 GADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS-S 280
+ ++FRPER+ + DP + F TG R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467
Query: 281 DVTDLEFKL--EAILRPHRGHYIAIERR 306
T + KL + +L+P + + ++ R
Sbjct: 468 KETQIPLKLDTQGLLQPEKPIVLKVDSR 495
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 114 bits (275), Expect = 3e-25
Identities = 64/208 (30%), Positives = 116/208 (55%), Gaps = 4/208 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ L L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PVA + R +V++ P GS ++ + +H +
Sbjct: 348 DAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKY 407
Query: 222 GADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS-S 280
+ ++FRPER+ + DP + F TG R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467
Query: 281 DVTDLEFKL--EAILRPHRGHYIAIERR 306
T + KL + +L+P + + ++ R
Sbjct: 468 KETQIPLKLDTQGLLQPEKPIVLKVDSR 495
>AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 519
Score = 114 bits (274), Expect = 4e-25
Identities = 79/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ +++ + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNLEVFDPSRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPMARLVLKSKNGIHLRLRR 508
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 114 bits (274), Expect = 4e-25
Identities = 79/298 (26%), Positives = 144/298 (48%), Gaps = 15/298 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ +++ + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNLEVFDPSRFAPGSAQHSHAFLP-F 450
Query: 249 STGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
S G R+CIGK +AM +K + L R+ + D T + + +L+ G ++ + R
Sbjct: 451 SGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 508
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 113 bits (273), Expect = 6e-25
Identities = 64/208 (30%), Positives = 116/208 (55%), Gaps = 4/208 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ L L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PVA + R +V++ P GS ++ + +H +
Sbjct: 348 DAVVQMEYLDMVVNETLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKY 407
Query: 222 GADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS-S 280
+ ++FRPER+ + DP + F TG R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPC 467
Query: 281 DVTDLEFKL--EAILRPHRGHYIAIERR 306
T + KL + +L+P + + ++ R
Sbjct: 468 KETQIPLKLDTQGLLQPEKPIVLKVDSR 495
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 109 bits (261), Expect = 2e-23
Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 11/269 (4%)
Query: 23 YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
Y +A+ ++ + +R F H D V+ + + + + LH + +Q RK
Sbjct: 211 YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKD 270
Query: 83 E--HDAASDKP---TDIILETCGGA---FSDKDVREEVDNIIFAGHDTISTVLTTALSLL 134
+ D + DI+L FS+ D++ EV +FAGHDT S+ ++ L L
Sbjct: 271 KLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCL 330
Query: 135 GSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAE 194
+P+ Q + +E+R +LGD +T E ++ Y +KE +R+Y I+R D
Sbjct: 331 AKYPEHQQRCRDEIRELLGDGS-SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKP 389
Query: 195 VKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGFSTGR 252
+ + + PAG + +W +H + + D F P R+ E + P F FS G
Sbjct: 390 ITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGL 449
Query: 253 RSCIGKVYAMMSMKTTLSFLLRRYRVSSD 281
R+CIG+ +A++ K ++ L R++++ D
Sbjct: 450 RNCIGQHFAIIECKVAVALTLLRFKLAPD 478
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 109 bits (261), Expect = 2e-23
Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 11/269 (4%)
Query: 23 YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
Y +A+ ++ + +R F H D V+ + + + + LH + +Q RK
Sbjct: 211 YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKD 270
Query: 83 E--HDAASDKP---TDIILETCGGA---FSDKDVREEVDNIIFAGHDTISTVLTTALSLL 134
+ D + DI+L FS+ D++ EV +FAGHDT S+ ++ L L
Sbjct: 271 KLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCL 330
Query: 135 GSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAE 194
+P+ Q + +E+R +LGD +T E ++ Y +KE +R+Y I+R D
Sbjct: 331 AKYPEHQQRCRDEIRELLGDGS-SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKP 389
Query: 195 VKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGFSTGR 252
+ + + PAG + +W +H + + D F P R+ E + P F FS G
Sbjct: 390 ITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGL 449
Query: 253 RSCIGKVYAMMSMKTTLSFLLRRYRVSSD 281
R+CIG+ +A++ K ++ L R++++ D
Sbjct: 450 RNCIGQHFAIIECKVAVALTLLRFKLAPD 478
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 109 bits (261), Expect = 2e-23
Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 11/269 (4%)
Query: 23 YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
Y +A+ ++ + +R F H D V+ + + + + LH + +Q RK
Sbjct: 211 YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKD 270
Query: 83 E--HDAASDKP---TDIILETCGGA---FSDKDVREEVDNIIFAGHDTISTVLTTALSLL 134
+ D + DI+L FS+ D++ EV +FAGHDT S+ ++ L L
Sbjct: 271 KLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCL 330
Query: 135 GSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAE 194
+P+ Q + +E+R +LGD +T E ++ Y +KE +R+Y I+R D
Sbjct: 331 AKYPEHQQRCRDEIRELLGDGS-SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKP 389
Query: 195 VKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGFSTGR 252
+ + + PAG + +W +H + + D F P R+ E + P F FS G
Sbjct: 390 ITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGL 449
Query: 253 RSCIGKVYAMMSMKTTLSFLLRRYRVSSD 281
R+CIG+ +A++ K ++ L R++++ D
Sbjct: 450 RNCIGQHFAIIECKVAVALTLLRFKLAPD 478
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 109 bits (261), Expect = 2e-23
Identities = 71/269 (26%), Positives = 128/269 (47%), Gaps = 11/269 (4%)
Query: 23 YEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQ 82
Y +A+ ++ + +R F H D V+ + + + + LH + +Q RK
Sbjct: 211 YLKAVFNLSKISNQRMNNFLHHNDLVFKFSSQGQIFSKFNQELHQFTEKVIQDRKESLKD 270
Query: 83 E--HDAASDKP---TDIILETCGGA---FSDKDVREEVDNIIFAGHDTISTVLTTALSLL 134
+ D + DI+L FS+ D++ EV +FAGHDT S+ ++ L L
Sbjct: 271 KLKQDTTQKRRWDFLDILLSAKSENTKDFSEADLQAEVKTFMFAGHDTTSSAISWILYCL 330
Query: 135 GSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAE 194
+P+ Q + +E+R +LGD +T E ++ Y +KE +R+Y I+R D
Sbjct: 331 AKYPEHQQRCRDEIRELLGDGS-SITWEHLSQMPYTTMCIKECLRLYAPVVNISRLLDKP 389
Query: 195 VKLKN-YTAPAGSGFILLLWGVHQHRIWGADADQFRPERW-LEAATLPDPSFFAGFSTGR 252
+ + + PAG + +W +H + + D F P R+ E + P F FS G
Sbjct: 390 ITFPDGRSLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHPYAFIPFSAGL 449
Query: 253 RSCIGKVYAMMSMKTTLSFLLRRYRVSSD 281
R+CIG+ +A++ K ++ L R++++ D
Sbjct: 450 RNCIGQHFAIIECKVAVALTLLRFKLAPD 478
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 106 bits (255), Expect = 9e-23
Identities = 81/300 (27%), Positives = 143/300 (47%), Gaps = 17/300 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNT-ALQQRKS 78
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H + +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLSHQHTRPKVIQLRKA 273
Query: 79 VFLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 QLQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISW 333
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIAR 189
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 ILYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGR 392
Query: 190 YSDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAG 247
V + + P G +L ++G+H + ++W + + F P R+ + +F
Sbjct: 393 ELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP- 450
Query: 248 FSTGRRSCIGKVYAMMSMKTTLSFL-LRRYRVSSDVTDLEFKL-EAILRPHRGHYIAIER 305
FS G R+CIGK +AM +K L L R+ + D T + + +L+ G ++ + R
Sbjct: 451 FSGGSRNCIGKQFAMNELKVGQQALTLVRFELLPDPTRIPIPIARLVLKSKNGIHLRLRR 510
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 139 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 197
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 198 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 257
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 258 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 317
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 318 CKETQIPLKLSLGGLLQPEKPVVLKVESR 346
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 216 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 274
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 275 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 334
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 335 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 394
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 395 CKETQIPLKLSLGGLLQPEKPVVLKVESR 423
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 102 bits (244), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 101 bits (243), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 101 bits (243), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 290 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 348
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 349 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 408
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 409 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 468
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 469 CKETQIPLKLSLGGLLQPEKPVVLKVESR 497
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 101 bits (243), Expect = 2e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 290 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 348
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 349 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 408
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 409 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 468
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 469 CKETQIPLKLSLGGLLQPEKPVVLKVESR 497
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 101 bits (241), Expect = 4e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 101 bits (241), Expect = 4e-21
Identities = 60/209 (28%), Positives = 113/209 (54%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 288 ALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 346
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 347 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKY 406
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 407 WTEPEKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 467 CKETQIPLKLSLGGLLQPEKPVVLKVESR 495
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 100 bits (239), Expect = 7e-21
Identities = 60/209 (28%), Positives = 112/209 (53%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG +T S+VL+ + L +HPDVQ K+ E+ VL + + T
Sbjct: 289 ALSDLELVAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L++EYL+ V+ E++R++P+A + R +V++ P G ++ + +H+ +
Sbjct: 348 DTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYR--- 277
+ ++F PER+ + DP + F +G R+CIG +A+M+MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
Query: 278 VSSDVTDLEFKLEAILRPHRGHYIAIERR 306
L+ L +L+P + + +E R
Sbjct: 468 CKETQIPLKLSLGGLLQPEKPVVLKVESR 496
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 99.1 bits (236), Expect = 2e-20
Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 2/176 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ KV E+ VL + + T
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L+LEYL+ V+ E++R++PVA + R +V++ P G ++ + +H +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
+ ++F PER+ + DP + F +G R+CIG +A+++MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 99.1 bits (236), Expect = 2e-20
Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 2/176 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ KV E+ VL + + T
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L+LEYL+ V+ E++R++PVA + R +V++ P G ++ + +H +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
+ ++F PER+ + DP + F +G R+CIG +A+++MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 99.1 bits (236), Expect = 2e-20
Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 2/176 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ KV E+ VL + + T
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L+LEYL+ V+ E++R++PVA + R +V++ P G ++ + +H +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
+ ++F PER+ + DP + F +G R+CIG +A+++MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 99.1 bits (236), Expect = 2e-20
Identities = 56/176 (31%), Positives = 100/176 (56%), Gaps = 2/176 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IFAG++T S+VL+ + L +HPDVQ KV E+ VL + + T
Sbjct: 289 ALSDLELMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPN-KAPPTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ L+LEYL+ V+ E++R++PVA + R +V++ P G ++ + +H +
Sbjct: 348 DTVLQLEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
+ ++F PER+ + DP + F +G R+CIG +A+++MK L +L+ +
Sbjct: 408 WTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNF 463
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 96.3 bits (229), Expect = 1e-19
Identities = 64/204 (31%), Positives = 98/204 (48%), Gaps = 2/204 (0%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
S K++ V + A +T + L L L +P VQ K+ E++ VL + +R +ED
Sbjct: 311 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRP-REED 369
Query: 164 YLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGA 223
+ YL+A LKESMR+ P P R D L Y P G+ +L +
Sbjct: 370 LRNMPYLKACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFE 429
Query: 224 DADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSDV 282
D+ QFRPERWL+ +P F G+R CIG+ A + + L +++R+Y + ++D
Sbjct: 430 DSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDN 489
Query: 283 TDLEFKLEAILRPHRGHYIAIERR 306
+E L P R IA +R
Sbjct: 490 EPVEMLHSGTLVPSRELPIAFCQR 513
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 95.1 bits (226), Expect = 3e-19
Identities = 65/225 (28%), Positives = 112/225 (49%), Gaps = 4/225 (1%)
Query: 51 RTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEHDAASDKPTDIILETCGGAFSDKDVRE 110
R +L+E + I + L + +Q+R+ + + +D T I L+ GA D+ + +
Sbjct: 237 RKQLREVRESI-RFLRQVGRDWVQRRREALKRGEEVPADILTQI-LKAEEGAQDDEGLLD 294
Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
AGH+T + L + L P++ ++ EV V+G ++R + ED RL+YL
Sbjct: 295 NFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDLGRLQYL 353
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
VLKES+R+YP A R + E + P + + + + + + D F P
Sbjct: 354 SQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNP 413
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
+R+ A P ++F FS G RSCIG+ +A M +K ++ LL+R
Sbjct: 414 DRFGPGAPKPRFTYFP-FSLGHRSCIGQQFAQMEVKVVMAKLLQR 457
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 95.1 bits (226), Expect = 3e-19
Identities = 65/225 (28%), Positives = 112/225 (49%), Gaps = 4/225 (1%)
Query: 51 RTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEHDAASDKPTDIILETCGGAFSDKDVRE 110
R +L+E + I + L + +Q+R+ + + +D T I L+ GA D+ + +
Sbjct: 237 RKQLREVRESI-RFLRQVGRDWVQRRREALKRGEEVPADILTQI-LKAEEGAQDDEGLLD 294
Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
AGH+T + L + L P++ ++ EV V+G ++R + ED RL+YL
Sbjct: 295 NFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDLGRLQYL 353
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
VLKES+R+YP A R + E + P + + + + + + D F P
Sbjct: 354 SQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPLTFNP 413
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
+R+ A P ++F FS G RSCIG+ +A M +K ++ LL+R
Sbjct: 414 DRFGPGAPKPRFTYFP-FSLGHRSCIGQQFAQMEVKVVMAKLLQR 457
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 94.7 bits (225), Expect = 4e-19
Identities = 57/204 (27%), Positives = 109/204 (53%), Gaps = 8/204 (3%)
Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
G S ++ + ++ AG DT S LT AL L P++Q+ ++ EV V+ A +
Sbjct: 317 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQ 375
Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
+D+ + L+AVLKE++R+YPV P +R + E+++ + P + F+ + V +
Sbjct: 376 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 435
Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
++ + F+P RWL + AT + P F G R+C+G+ A + M+ L+ L+++
Sbjct: 436 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 495
Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
Y+V + + +L+ +L P++
Sbjct: 496 YKVVLAPETGELKSVARIVLVPNK 519
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 94.7 bits (225), Expect = 4e-19
Identities = 57/204 (27%), Positives = 109/204 (53%), Gaps = 8/204 (3%)
Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
G S ++ + ++ AG DT S LT AL L P++Q+ ++ EV V+ A +
Sbjct: 318 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQ 376
Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
+D+ + L+AVLKE++R+YPV P +R + E+++ + P + F+ + V +
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436
Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
++ + F+P RWL + AT + P F G R+C+G+ A + M+ L+ L+++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496
Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
Y+V + + +L+ +L P++
Sbjct: 497 YKVVLAPETGELKSVARIVLVPNK 520
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 94.7 bits (225), Expect = 4e-19
Identities = 57/204 (27%), Positives = 109/204 (53%), Gaps = 8/204 (3%)
Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
G S ++ + ++ AG DT S LT AL L P++Q+ ++ EV V+ A +
Sbjct: 318 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQ 376
Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
+D+ + L+AVLKE++R+YPV P +R + E+++ + P + F+ + V +
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436
Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
++ + F+P RWL + AT + P F G R+C+G+ A + M+ L+ L+++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496
Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
Y+V + + +L+ +L P++
Sbjct: 497 YKVVLAPETGELKSVARIVLVPNK 520
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 94.7 bits (225), Expect = 4e-19
Identities = 57/204 (27%), Positives = 109/204 (53%), Gaps = 8/204 (3%)
Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
G S ++ + ++ AG DT S LT AL L P++Q+ ++ EV V+ A +
Sbjct: 318 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVV-PAGQVPQ 376
Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
+D+ + L+AVLKE++R+YPV P +R + E+++ + P + F+ + V +
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436
Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
++ + F+P RWL + AT + P F G R+C+G+ A + M+ L+ L+++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496
Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
Y+V + + +L+ +L P++
Sbjct: 497 YKVVLAPETGELKSVARIVLVPNK 520
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 138 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 197
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 198 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 257
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 258 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 315
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 316 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 371
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 372 RRFHVKT 378
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 94.3 bits (224), Expect = 5e-19
Identities = 65/247 (26%), Positives = 125/247 (50%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTAL-QQRKSVFLQEH-DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + ++R+ + +E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRRRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 94.3 bits (224), Expect = 5e-19
Identities = 55/189 (29%), Positives = 91/189 (48%), Gaps = 3/189 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYL-RLEYL 170
V ++ AG DT+S L+ AL L HP+VQ +++E+ L L +L L
Sbjct: 311 VTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPSATVLSQLPLL 370
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
+AV+KE +R+YPV P +R D ++ + +Y P + L + + + + FRP
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSD--VTDLEFK 288
RWL P P F G+RSC+G+ A + ++ L+ +L + V + + K
Sbjct: 431 ARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQPEPGAAPVRPK 490
Query: 289 LEAILRPHR 297
+L P R
Sbjct: 491 TRTVLVPER 499
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 93.9 bits (223), Expect = 6e-19
Identities = 57/204 (27%), Positives = 108/204 (52%), Gaps = 8/204 (3%)
Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
G S ++ + ++ AG DT S LT AL L P++Q ++ EV V+ A +
Sbjct: 318 GQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVV-PAGQVPQ 376
Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
+D+ + L+AVLKE++R+YPV P +R + E+++ + P + F+ + V +
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVSRDPT 436
Query: 221 WGADADQFRPERWL---EAAT--LPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
++ + F+P RWL + AT + P F G R+C+G+ A + M+ L+ L+++
Sbjct: 437 AFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQK 496
Query: 276 YRV--SSDVTDLEFKLEAILRPHR 297
Y+V + + +L+ +L P++
Sbjct: 497 YKVVLAPETGELKSVARIVLVPNK 520
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 93.5 bits (222), Expect = 9e-19
Identities = 65/205 (31%), Positives = 97/205 (47%), Gaps = 4/205 (1%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK-E 162
S K++ V + A +T + L L L +P VQ K+ E++ VL E V + E
Sbjct: 170 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL--PENQVPRAE 227
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
D + YL+A LKESMR+ P P R D L Y P G+ +L +
Sbjct: 228 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 287
Query: 223 ADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSD 281
D+ QFRPERWL+ +P F G+R CIG+ A + + L +++R+Y + ++D
Sbjct: 288 EDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATD 347
Query: 282 VTDLEFKLEAILRPHRGHYIAIERR 306
+E L P R IA +R
Sbjct: 348 NEPVEMLHSGTLVPSRELPIAFCQR 372
>AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 93.5 bits (222), Expect = 9e-19
Identities = 65/205 (31%), Positives = 97/205 (47%), Gaps = 4/205 (1%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK-E 162
S K++ V + A +T + L L L +P VQ K+ E++ VL E V + E
Sbjct: 312 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL--PENQVPRAE 369
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
D + YL+A LKESMR+ P P R D L Y P G+ +L +
Sbjct: 370 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 429
Query: 223 ADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSD 281
D+ QFRPERWL+ +P F G+R CIG+ A + + L +++R+Y + ++D
Sbjct: 430 EDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATD 489
Query: 282 VTDLEFKLEAILRPHRGHYIAIERR 306
+E L P R IA +R
Sbjct: 490 NEPVEMLHSGTLVPSRELPIAFCQR 514
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 93.5 bits (222), Expect = 9e-19
Identities = 65/205 (31%), Positives = 97/205 (47%), Gaps = 4/205 (1%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK-E 162
S K++ V + A +T + L L L +P VQ K+ E++ VL E V + E
Sbjct: 170 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL--PENQVPRAE 227
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
D + YL+A LKESMR+ P P R D L Y P G+ +L +
Sbjct: 228 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 287
Query: 223 ADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSD 281
D+ QFRPERWL+ +P F G+R CIG+ A + + L +++R+Y + ++D
Sbjct: 288 EDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATD 347
Query: 282 VTDLEFKLEAILRPHRGHYIAIERR 306
+E L P R IA +R
Sbjct: 348 NEPVEMLHSGTLVPSRELPIAFCQR 372
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 93.5 bits (222), Expect = 9e-19
Identities = 62/199 (31%), Positives = 97/199 (48%), Gaps = 7/199 (3%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV-T 160
A + +++ V ++ AG DT S L+ + LL HP+VQ VY E+ + LG ER V T
Sbjct: 164 ALTLQEIYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLG--ERHVPT 221
Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D ++ + A+LKE++R++PV P R + ++ + Y P G+ L +
Sbjct: 222 AADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDE 281
Query: 221 WGADADQFRPERWLEAATLPDPSFFAG--FSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV 278
A +FRPERWL L F F G RSCIG+ A + + + LL+ + +
Sbjct: 282 NFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEI 341
Query: 279 --SSDVTDLEFKLEAILRP 295
SS + K +L P
Sbjct: 342 KTSSQTNAVHAKTHGLLTP 360
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 93.1 bits (221), Expect = 1e-18
Identities = 64/247 (25%), Positives = 122/247 (49%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEH--DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + +++ E + D T+
Sbjct: 138 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECMDFATE 197
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 198 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 257
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 258 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 315
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 316 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 371
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 372 RRFHVKT 378
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 93.1 bits (221), Expect = 1e-18
Identities = 64/247 (25%), Positives = 122/247 (49%), Gaps = 8/247 (3%)
Query: 36 ERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEH--DAASDKPTD 93
+ +Q + D + + L ++ ++ +K L + + +++ E + D T+
Sbjct: 222 DAWQALLIKPDIFFKISWLYKKYEKSVKDLKDAIEVLIAEKRCRISTEEKLEECMDFATE 281
Query: 94 IILETCGGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLG 153
+IL G + ++V + + ++ A DT+S L L L+ HP+V++ + E++ V+G
Sbjct: 282 LILAEKRGDLTRENVNQCILEMLIAAPDTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIG 341
Query: 154 DAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLW 213
ERD+ +D +L+ +E + ESMR PV ++ R + + + Y G+ IL +
Sbjct: 342 --ERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIG 399
Query: 214 GVHQHRIWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLL 273
+H+ + ++F E + A +P +F F G R C GK AM+ MK L LL
Sbjct: 400 RMHRLEFF-PKPNEFTLENF--AKNVP-YRYFQPFGFGPRGCAGKYIAMVMMKAILVTLL 455
Query: 274 RRYRVSS 280
RR+ V +
Sbjct: 456 RRFHVKT 462
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 92.7 bits (220), Expect = 1e-18
Identities = 62/196 (31%), Positives = 93/196 (47%), Gaps = 4/196 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK-E 162
S K++ V + A +T + L L L +P VQ K+ E++ VL E V + E
Sbjct: 55 SKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVL--PENQVPRAE 112
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
D + YL+A LKESMR+ P P R D L Y P G+ +L +
Sbjct: 113 DLRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNF 172
Query: 223 ADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV-SSD 281
D+ QFRPERWL+ +P F G+R CIG+ A + + L +++R+Y + ++D
Sbjct: 173 EDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATD 232
Query: 282 VTDLEFKLEAILRPHR 297
+E L P R
Sbjct: 233 NEPVEMLHSGTLVPSR 248
>BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein.
Length = 372
Score = 92.7 bits (220), Expect = 1e-18
Identities = 61/199 (30%), Positives = 97/199 (48%), Gaps = 7/199 (3%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV-T 160
A + +++ V ++ AG DT S L+ + +L HP+VQ VY E+ + LG ER V T
Sbjct: 164 ALTLQEIYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLG--ERHVPT 221
Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D ++ + A+LKE++R++PV P R + ++ + Y P G+ L +
Sbjct: 222 AADVPKVPLVRALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDE 281
Query: 221 WGADADQFRPERWLEAATLPDPSFFAG--FSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV 278
A +FRPERWL L F F G RSCIG+ A + + + LL+ + +
Sbjct: 282 NFPRAKEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEI 341
Query: 279 --SSDVTDLEFKLEAILRP 295
SS + K +L P
Sbjct: 342 KTSSQTNAVHAKTHGLLTP 360
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLAN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
+ ++F PER+ + D + F G R+CIG +A+ ++K + L+ +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 92.3 bits (219), Expect = 2e-18
Identities = 57/177 (32%), Positives = 95/177 (53%), Gaps = 5/177 (2%)
Query: 104 SDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKED 163
SD + + +I AG +T ++V+ L+ L +P V+ K+Y E+ + +G R T D
Sbjct: 288 SDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVG-FSRTPTISD 346
Query: 164 YLRLEYLEAVLKESMRMYPVAP-VIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWG 222
RL LEA ++E +R+ PVAP +I ++ + + + G+ I+ LW +H +
Sbjct: 347 RNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEW 406
Query: 223 ADADQFRPERWLEAA--TLPDPSF-FAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
DQF PER+L A L PS + F G RSCIG++ A + +++LL+R+
Sbjct: 407 HQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRF 463
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 179 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 237
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 238 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 297
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
+ ++F PER+ + D + F G R+CIG +A+ ++K + L+ +
Sbjct: 298 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 357
Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 358 CKETQIPLKLDNLPILQPEKPIVLKVHLR 386
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 91.5 bits (217), Expect = 3e-18
Identities = 66/245 (26%), Positives = 117/245 (47%), Gaps = 14/245 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450
Query: 249 STGRR 253
S G R
Sbjct: 451 SGGSR 455
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
+ ++F PER+ + D + F G R+CIG +A+ ++K + L+ +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 91.5 bits (217), Expect = 3e-18
Identities = 66/245 (26%), Positives = 117/245 (47%), Gaps = 14/245 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ ++ R + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHSLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNPEVFDPFRFAPGSAQHSHAFLP-F 450
Query: 249 STGRR 253
S G R
Sbjct: 451 SGGSR 455
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
+ ++F PER+ + D + F G R+CIG +A+ ++K + L+ +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
+ ++F PER+ + D + F G R+CIG +A+ ++K + L+ +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
+ ++F PER+ + D + F G R+CIG +A+ ++K + L+ +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 91.5 bits (217), Expect = 3e-18
Identities = 57/209 (27%), Positives = 108/209 (51%), Gaps = 5/209 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS- 279
+ ++F PER+ + D + F G R+CIG +A+ ++K + L+ +
Sbjct: 408 WTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
Query: 280 SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 468 CKETQIPLKLDNLPILQPEKPIVLKVHLR 496
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 90.6 bits (215), Expect = 6e-18
Identities = 61/209 (29%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
FS +++ V +I AG +T + VL A+ + +P++Q +V E+ ++G + + +
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKP-SWD 353
Query: 163 DYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D ++ Y EAVL E +R + P+ I + + ++ Y+ P G+ I L+ VH +
Sbjct: 354 DKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKY 413
Query: 222 GADADQFRPERWLEAA-TLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
D + F PER+L+++ FS GRR C+G+ A M M + LL+R+ +
Sbjct: 414 WRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473
Query: 281 D---VTDLEFKLEAILRPHRGHYIAIERR 306
V DL+ +L L+P + + I ERR
Sbjct: 474 PHELVPDLKPRLGMTLQP-QPYLICAERR 501
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 90.6 bits (215), Expect = 6e-18
Identities = 61/209 (29%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
FS +++ V +I AG +T + VL A+ + +P++Q +V E+ ++G + + +
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKP-SWD 353
Query: 163 DYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D ++ Y EAVL E +R + P+ I + + ++ Y+ P G+ I L+ VH +
Sbjct: 354 DKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKY 413
Query: 222 GADADQFRPERWLEAA-TLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
D + F PER+L+++ FS GRR C+G+ A M M + LL+R+ +
Sbjct: 414 WRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473
Query: 281 D---VTDLEFKLEAILRPHRGHYIAIERR 306
V DL+ +L L+P + + I ERR
Sbjct: 474 PHELVPDLKPRLGMTLQP-QPYLICAERR 501
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 90.6 bits (215), Expect = 6e-18
Identities = 61/209 (29%), Positives = 108/209 (51%), Gaps = 7/209 (3%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
FS +++ V +I AG +T + VL A+ + +P++Q +V E+ ++G + + +
Sbjct: 295 FSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKP-SWD 353
Query: 163 DYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D ++ Y EAVL E +R + P+ I + + ++ Y+ P G+ I L+ VH +
Sbjct: 354 DKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKY 413
Query: 222 GADADQFRPERWLEAA-TLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
D + F PER+L+++ FS GRR C+G+ A M M + LL+R+ +
Sbjct: 414 WRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHF 473
Query: 281 D---VTDLEFKLEAILRPHRGHYIAIERR 306
V DL+ +L L+P + + I ERR
Sbjct: 474 PHELVPDLKPRLGMTLQP-QPYLICAERR 501
>BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family 2,
subfamily W, polypeptide 1 protein.
Length = 490
Score = 89.4 bits (212), Expect = 1e-17
Identities = 60/179 (33%), Positives = 85/179 (47%), Gaps = 2/179 (1%)
Query: 101 GAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVT 160
G F++ + +++ AG +T S L A L+G HPDVQ +V E+ RVLG R
Sbjct: 279 GLFAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPG-RTPR 337
Query: 161 KEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
ED L Y AVL E R + P + R + A+ +L + P G+ I LL V
Sbjct: 338 LEDQQALPYTSAVLHEVQRFITLLPHVPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDET 397
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV 278
QF P +L+A F FS GRR C+G+ A + + LL+RYR+
Sbjct: 398 QWQTPGQFNPGHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQRYRL 456
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 89.0 bits (211), Expect = 2e-17
Identities = 65/245 (26%), Positives = 117/245 (47%), Gaps = 14/245 (5%)
Query: 20 NQQYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV 79
+Q Y QA+ D+ +++ + + D +Y+ T + ++ H ++ +Q RK+
Sbjct: 214 SQSYIQAISDLNSLVFCCMRNAFHENDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQ 273
Query: 80 FLQEHDAASDKPT------DIILETC---GGAFSDKDVREEVDNIIFAGHDTISTVLTTA 130
+E + K DI+L G SDKD+R EVD +F GHDT ++ ++
Sbjct: 274 LQKEGELEKIKRKRHLDFLDILLLAKMENGSILSDKDLRAEVDTFMFEGHDTTASGISWI 333
Query: 131 LSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYPVAPVIARY 190
L L +HP Q++ E+ +LGD +T ++ Y +KE++R+YP P I R
Sbjct: 334 LYALATHPKHQERCREEIHGLLGDG-ASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 191 SDAEVKLKN-YTAPAGSGFILLLWGVHQH-RIWGADADQFRPERWLEAATLPDPSFFAGF 248
V + + P G +L ++G+H + ++W + + F P R+ + +F F
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVW-PNLEVFDPSRFAPGSAQHSHAFLP-F 450
Query: 249 STGRR 253
S G R
Sbjct: 451 SGGSR 455
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 88.2 bits (209), Expect = 3e-17
Identities = 56/210 (26%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPERWLEAATLP--DPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+ ++F PE D + F G R+CIG +A+ ++K + L+ +
Sbjct: 408 WTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 467
Query: 280 -SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 468 PCKETQIPLKLDNLPILQPEKPIVLKVHLR 497
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 88.2 bits (209), Expect = 3e-17
Identities = 56/210 (26%), Positives = 105/210 (50%), Gaps = 6/210 (2%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPERWLEAATLP--DPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+ ++F PE D + F G R+CIG +A+ ++K + L+ +
Sbjct: 408 WTEPEKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFK 467
Query: 280 -SDVTDLEFKLE--AILRPHRGHYIAIERR 306
T + KL+ IL+P + + + R
Sbjct: 468 PCKETQIPLKLDNLPILQPEKPIVLKVHLR 497
>X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C
protein.
Length = 356
Score = 87.0 bits (206), Expect = 7e-17
Identities = 71/240 (29%), Positives = 114/240 (47%), Gaps = 19/240 (7%)
Query: 63 KVLHNMSNTALQQRKSVFLQEHDAASD--KPTDIILETCGGAFSDKDVREE---VDNIIF 117
KVL N++ T R+ V +EH A+ D P D I +KD ++ ++N++
Sbjct: 98 KVLKNVALTRSYIREKV--KEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFTIENLVI 155
Query: 118 -------AGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
AG +T ST L AL LL HP+V KV E+ RV+G R +D + Y
Sbjct: 156 TAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYT 214
Query: 171 EAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFR 229
+AV+ E R + P ++ ++K +NY P G+ + L V + + F
Sbjct: 215 DAVVHEVQRYIDLIPTSLPHAVTCDIKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFD 274
Query: 230 PERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
P +L E ++F FS G+R C+G+ A M + L+F+L+ + + S D DL+
Sbjct: 275 PRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 334
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 86.6 bits (205), Expect = 1e-16
Identities = 57/188 (30%), Positives = 92/188 (48%), Gaps = 5/188 (2%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + V ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 162 FTVESLIATVTDMFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQ 220
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ +VK +NY P G+ + L V
Sbjct: 221 DRSHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKE 280
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E ++F FS G+R C+G+ A M + L+F+L+ + + S
Sbjct: 281 FPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKS 340
Query: 281 --DVTDLE 286
D DL+
Sbjct: 341 LIDPKDLD 348
>M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein.
Length = 490
Score = 85.8 bits (203), Expect = 2e-16
Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
+++ AG +T ST L AL LL HP+V KV E+ RV+G R +D + Y +AV
Sbjct: 293 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRGHMPYTDAV 351
Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P ++ +VK +NY P G+ + L V + + F P
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 411
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
+L E ++F FS G+R C+G+ A M + L+F+L+ + + S D DL+
Sbjct: 412 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 468
>L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxylase
protein.
Length = 217
Score = 85.8 bits (203), Expect = 2e-16
Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
+++ AG +T ST L AL LL HP+V KV E+ RV+G R +D + Y +AV
Sbjct: 20 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQDRGHMPYTDAV 78
Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P ++ +VK +NY P G+ + L V + + F P
Sbjct: 79 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 138
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
+L E ++F FS G+R C+G+ A M + L+F+L+ + + S D DL+
Sbjct: 139 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 195
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 251 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 309
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 310 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 369
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 370 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 418
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein.
Length = 468
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
+++ AG +T ST L AL LL HP+V KV E+ RV+G R +D + Y +AV
Sbjct: 271 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYTDAV 329
Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P ++ +VK +NY P G+ + L V + + F P
Sbjct: 330 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 389
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
+L E ++F FS G+R C+G+ A M + L+F+L+ + + S D DL+
Sbjct: 390 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 446
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
+++ AG +T ST L AL LL HP+V KV E+ RV+G R +D + Y +AV
Sbjct: 293 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYTDAV 351
Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P ++ +VK +NY P G+ + L V + + F P
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 411
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
+L E ++F FS G+R C+G+ A M + L+F+L+ + + S D DL+
Sbjct: 412 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 468
>AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
+++ AG +T ST L AL LL HP+V KV E+ RV+G R +D + Y +AV
Sbjct: 293 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYTDAV 351
Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P ++ +VK +NY P G+ + L V + + F P
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 411
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
+L E ++F FS G+R C+G+ A M + L+F+L+ + + S D DL+
Sbjct: 412 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 468
>AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 19 protein.
Length = 490
Score = 85.4 bits (202), Expect = 2e-16
Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 5/177 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
+++ AG +T ST L AL LL HP+V KV E+ RV+G R +D + Y +AV
Sbjct: 293 DLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVG-RNRSPCMQDRGHMPYTDAV 351
Query: 174 LKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P ++ +VK +NY P G+ + L V + + F P
Sbjct: 352 VHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRH 411
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS--DVTDLE 286
+L E ++F FS G+R C+G+ A M + L+F+L+ + + S D DL+
Sbjct: 412 FLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLD 468
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 85.4 bits (202), Expect = 2e-16
Identities = 67/225 (29%), Positives = 111/225 (49%), Gaps = 14/225 (6%)
Query: 51 RTKLKEREDQIIKVLHNMSNTALQQRKSVFLQEHDAASDKPTDIILETCGGAFSDKDVRE 110
R +L+E + I + L + +Q+R+ + + +D T I L+ GA D+ + +
Sbjct: 84 RKQLREVRESI-RFLRQVGRDWVQRRREALKRGEEVPADILTQI-LKAEEGAQDDEGLLD 141
Query: 111 EVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYL 170
AGH+T + L + L P++ ++ EV V+G ++R + ED RL+YL
Sbjct: 142 NFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFEDLGRLQYL 200
Query: 171 EAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
VLKES+R+YP A R + E + GF + G + + D F P
Sbjct: 201 SQVLKESLRLYPPAWGTFRLLEEETLI--------DGFSTYVMG--RMDTYFEDPLTFNP 250
Query: 231 ERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRR 275
+R+ A P ++F FS G RSCIG+ +A M +K ++ LL+R
Sbjct: 251 DRFGPGAPKPRFTYFP-FSLGHRSCIGQQFAQMEVKVVMAKLLQR 294
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 85.4 bits (202), Expect = 2e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 85.0 bits (201), Expect = 3e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ AG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRTKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L + F FS G+R C G+ A M + + +++ +R+ S
Sbjct: 416 FLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLKS 464
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 85.0 bits (201), Expect = 3e-16
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ AG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L + F FS G+R C G+ A M + + +++ +R+ S
Sbjct: 416 FLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRLKS 464
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 83.8 bits (198), Expect = 7e-16
Identities = 49/169 (28%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP+V+ +V+ E+ RV+G R ED ++ Y+EAV
Sbjct: 292 NLFIGGTETVSTTLRYGFLLLMKHPEVEAQVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 350
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 351 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQH 410
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R+C G+ A M + + +++ +R+ S
Sbjct: 411 FLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKS 459
>S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein.
Length = 477
Score = 83.4 bits (197), Expect = 9e-16
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 269 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 327
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 328 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 387
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 388 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 447
>M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein.
Length = 383
Score = 83.4 bits (197), Expect = 9e-16
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 175 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 233
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 234 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 293
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 294 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 353
>D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein.
Length = 487
Score = 83.4 bits (197), Expect = 9e-16
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 279 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 337
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 338 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 397
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 398 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 457
>BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 83.4 bits (197), Expect = 9e-16
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 340
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460
>AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 83.4 bits (197), Expect = 9e-16
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 340
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460
>AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 83.4 bits (197), Expect = 9e-16
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 340
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460
>AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 9 protein.
Length = 490
Score = 83.4 bits (197), Expect = 9e-16
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 282 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 340
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 341 DRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 400
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 401 FPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 460
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 292 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 350
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 351 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 410
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 411 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 470
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 165 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 223
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 224 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 283
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 284 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 343
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 288 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 346
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 347 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 406
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 407 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 466
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 83.0 bits (196), Expect = 1e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
+ ++ AG DT + L L + +PDVQ+KV+ E+ RV+G A R + D ++ Y E
Sbjct: 346 IGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIG-ANRAPSLTDKAQMPYTE 404
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQH-RIWGADADQFR 229
A + E R+ V P+ I + L+ YT P G+ + LW VH+ IW D F
Sbjct: 405 ATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPED-FY 463
Query: 230 PERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSM 265
P R+L + L F F G+R C+G+ A M +
Sbjct: 464 PNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMEL 500
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 83.0 bits (196), Expect = 1e-15
Identities = 52/157 (33%), Positives = 79/157 (50%), Gaps = 5/157 (3%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
+ ++ AG DT + L L + +PDVQ+KV+ E+ RV+G A R + D ++ Y E
Sbjct: 346 IGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIG-ANRAPSLTDKAQMPYTE 404
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQH-RIWGADADQFR 229
A + E R+ V P+ I + L+ YT P G+ + LW VH+ IW D F
Sbjct: 405 ATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPED-FY 463
Query: 230 PERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSM 265
P R+L + L F F G+R C+G+ A M +
Sbjct: 464 PNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMEL 500
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 83.0 bits (196), Expect = 1e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 358 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 416
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 417 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 476
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 477 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 536
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
++ FAG +T ST L AL + +P++Q+KV E+ RV+G ++ T + Y AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAV 365
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E RM + P+ + R + L Y P G+ + L +H+ A D F P+
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425
Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
+LE F FS G+R+C+G+ A + + L++++ +++ L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485
Query: 290 EAILRP 295
+ P
Sbjct: 486 GITISP 491
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/169 (29%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ AG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRTKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDLRFFSNPRDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS +R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLGEKGQFKKRDAFVPFSIRKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 82.6 bits (195), Expect = 2e-15
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 277 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 335
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 336 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 395
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 396 FPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 455
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 82.6 bits (195), Expect = 2e-15
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 3/180 (1%)
Query: 103 FSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKE 162
F+ + + ++ AG +T ST L AL LL HP+V KV E+ RV+G R +
Sbjct: 277 FTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIG-RNRSPCMQ 335
Query: 163 DYLRLEYLEAVLKESMRMYPVAPVIARYS-DAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
D + Y +AV+ E R + P ++ ++K +NY P G+ ++ L V
Sbjct: 336 DRSHMPYTDAVVHEVQRCIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKE 395
Query: 222 GADADQFRPERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ + F P +L E +F FS G+R C+G+ A M + L+ +L+ + + S
Sbjct: 396 FPNPEMFDPHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKS 455
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
++ FAG +T ST L AL + +P++Q+KV E+ RV+G ++ T + Y AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAV 365
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E RM + P+ + R + L Y P G+ + L +H+ A D F P+
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425
Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
+LE F FS G+R+C+G+ A + + L++++ +++ L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485
Query: 290 EAILRP 295
+ P
Sbjct: 486 GITISP 491
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
++ FAG +T ST L AL + +P++Q+KV E+ RV+G ++ T + Y AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAV 365
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E RM + P+ + R + L Y P G+ + L +H+ A D F P+
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425
Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
+LE F FS G+R+C+G+ A + + L++++ +++ L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485
Query: 290 EAILRP 295
+ P
Sbjct: 486 GITISP 491
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 82.6 bits (195), Expect = 2e-15
Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
++ FAG +T ST L AL + +P++Q+KV E+ RV+G ++ T + Y AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARE-SMPYTNAV 365
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E RM + P+ + R + L Y P G+ + L +H+ A D F P+
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425
Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
+LE F FS G+R+C+G+ A + + L++++ +++ L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485
Query: 290 EAILRP 295
+ P
Sbjct: 486 GITISP 491
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/180 (29%), Positives = 88/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++R V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13
variant 5 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ FAG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P+ +A + + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415
Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L+ F FS G+R C G+ A M + + +++ +R S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464
>AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13
variant 3 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ FAG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P+ +A + + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415
Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L+ F FS G+R C G+ A M + + +++ +R S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464
>AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13
variant 2 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ FAG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P+ +A + + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415
Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L+ F FS G+R C G+ A M + + +++ +R S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464
>AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13
variant 1 protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ FAG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P+ +A + + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415
Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L+ F FS G+R C G+ A M + + +++ +R S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464
>AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13
protein.
Length = 494
Score = 82.2 bits (194), Expect = 2e-15
Identities = 49/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ FAG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P+ +A + + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415
Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L+ F FS G+R C G+ A M + + +++ +R S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 82.2 bits (194), Expect = 2e-15
Identities = 50/186 (26%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
++ FAG +T ST L AL + +P++Q+KV E+ RV+G ++ T + Y AV
Sbjct: 307 DLFFAGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIGQGQQPSTAARE-SMPYTNAV 365
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E RM + P+ + R + L Y P G+ + L +H+ A D F P+
Sbjct: 366 IHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDH 425
Query: 233 WLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRV---SSDVTDLEFKL 289
+LE F FS G+R+C+G+ A + + L++++ +++ L+F++
Sbjct: 426 FLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRM 485
Query: 290 EAILRP 295
+ P
Sbjct: 486 GITISP 491
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 81.4 bits (192), Expect = 4e-15
Identities = 61/230 (26%), Positives = 110/230 (47%), Gaps = 12/230 (5%)
Query: 9 LGIKMEDHSAVNQQYEQALHDIF--AVLTERFQKFW-LHYDFVYNRTKLKEREDQIIKVL 65
LG + +++++YE+A F ++ T Q L R+ L E ++V+
Sbjct: 55 LGFSQQSTRSLSEKYEEAFKIGFFGSLFTLNIQSLAVLPRPECMVRSGLTETSTSWVRVI 114
Query: 66 ---HNMSNTALQQRKSVFLQEHDAASDKPTDIILETCGGAFSDKDVREEVDNIIFAGHDT 122
LQ R F Q D+ + K T A SD ++ + IIFA +DT
Sbjct: 115 LLPQPPEELGLQHRVDFFQQIIDSQNSKETK-----SHKALSDLELVAQSIIIIFAAYDT 169
Query: 123 ISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAVLKESMRMYP 182
ST L + L +HPDVQ K+ E+ VL + + VT + +++EYL+ V+ E++R++P
Sbjct: 170 TSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTYDALVQMEYLDMVVNETLRLFP 228
Query: 183 VAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
V + R ++++ P G ++ ++ +H + + ++F PER
Sbjct: 229 VVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 278
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 81.0 bits (191), Expect = 5e-15
Identities = 50/169 (29%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ AG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y+EAV
Sbjct: 297 NLFIAGTETVSTTLHYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+ +AR + K +++ P G +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGIEVFPMLGSVLRDLRFFSNPRDFNPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS +R+C G+ A M + + +++ +R+ S
Sbjct: 416 FLGEKGQFKKRDAFVPFSIRKRNCFGEGLARMELFLFFTTVMQNFRLKS 464
>AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13
variant 6 protein.
Length = 494
Score = 81.0 bits (191), Expect = 5e-15
Identities = 48/169 (28%), Positives = 85/169 (50%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ FAG +T+ST L LL HP+++ KV+ E+ RV+G R ED ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPELEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P+ +A + + K +++ P G+ +L V + + ++ F P+
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQH 415
Query: 233 WLE-AATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L+ F FS G+R C G+ A M + + +++ +R S
Sbjct: 416 FLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 81.0 bits (191), Expect = 5e-15
Identities = 42/150 (28%), Positives = 82/150 (54%), Gaps = 3/150 (2%)
Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHR 219
T + +++EYL+ V+ E++R++PVA + R +V++ P GS ++ + +H
Sbjct: 17 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDP 76
Query: 220 IWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+ + ++FRPER+ + DP + F TG R+CIG +A+M+MK L +L+ +
Sbjct: 77 KYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 136
Query: 280 -SDVTDLEFKL--EAILRPHRGHYIAIERR 306
T + KL + +L+P + + ++ R
Sbjct: 137 PCKETQIPLKLDTQGLLQPEKPIVLKVDSR 166
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 81.0 bits (191), Expect = 5e-15
Identities = 42/150 (28%), Positives = 82/150 (54%), Gaps = 3/150 (2%)
Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHR 219
T + +++EYL+ V+ E++R++PVA + R +V++ P GS ++ + +H
Sbjct: 4 TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDP 63
Query: 220 IWGADADQFRPERWLEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+ + ++FRPER+ + DP + F TG R+CIG +A+M+MK L +L+ +
Sbjct: 64 KYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFK 123
Query: 280 -SDVTDLEFKL--EAILRPHRGHYIAIERR 306
T + KL + +L+P + + ++ R
Sbjct: 124 PCKETQIPLKLDTQGLLQPEKPIVLKVDSR 153
>D12621-1|BAA02145.1| 389|Homo sapiens cytochrome P-450LTBV
protein.
Length = 389
Score = 80.6 bits (190), Expect = 6e-15
Identities = 49/170 (28%), Positives = 93/170 (54%), Gaps = 13/170 (7%)
Query: 22 QYEQALHDIFAVLTERFQKFWLHYDFVYNRTKLKEREDQIIKVLHNMSNTALQQRKSV-- 79
+Y A+ ++ A++T+R Q+ L+ DF+Y T +R + +++H+ ++ +Q+R+
Sbjct: 220 EYIAAILELSALVTKRHQQILLYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLP 279
Query: 80 ------FLQEHDAASDKP-TDIIL---ETCGGAFSDKDVREEVDNIIFAGHDTISTVLTT 129
FLQ + D++L + G SD+D+R E D +F GHDT ++ L+
Sbjct: 280 SQGVDDFLQAKAKSKTLDFIDVLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSW 339
Query: 130 ALSLLGSHPDVQDKVYNEVRRVLGDAE-RDVTKEDYLRLEYLEAVLKESM 178
L L HP+ Q++ EV+ +L D E +++ +D +L +L +KES+
Sbjct: 340 VLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESL 389
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 80.6 bits (190), Expect = 6e-15
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 292 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 350
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 351 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 410
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 411 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 470
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 357 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 357 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 79.8 bits (188), Expect = 1e-14
Identities = 52/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ V+G R
Sbjct: 238 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRP-EM 296
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 297 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 356
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 357 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 416
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 79.4 bits (187), Expect = 1e-14
Identities = 50/183 (27%), Positives = 89/183 (48%), Gaps = 3/183 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
V ++ FAG +T ST L L +L +P++++K++ E+ RV+G + K D + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
AV++E R + P + + + + Y P G+ + L V D ++F+P
Sbjct: 352 AVVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
E +L E +F FSTG+R C G+ A M + L +L+ + + V + L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471
Query: 290 EAI 292
I
Sbjct: 472 SPI 474
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 78.6 bits (185), Expect = 3e-14
Identities = 51/180 (28%), Positives = 87/180 (48%), Gaps = 3/180 (1%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
+F+D+++ V ++ AG T ST L L L+ HPDVQ +V E+ ++G R
Sbjct: 289 SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDMIGQVRRP-EM 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRI 220
D + Y AV+ E R + P+ + + +++++ + P G+ I L V +
Sbjct: 348 GDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEA 407
Query: 221 WGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVS 279
+F PE +L+A P F FS GRR+C+G+ A M + + LL+ + S
Sbjct: 408 VWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFS 467
>BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family 2,
subfamily S, polypeptide 1 protein.
Length = 504
Score = 78.6 bits (185), Expect = 3e-14
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 5/184 (2%)
Query: 100 GGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV 159
G F++K++ V ++FAG T+ST + L LL +P VQ V E+ R LG A +
Sbjct: 284 GTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG-AGQAP 342
Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGV-HQ 217
+ D RL Y +AVL E+ R+ + P+ I R + + YT P G+ LL + H
Sbjct: 343 SLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHD 402
Query: 218 HRIWGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
I+ ++F P+R+L+A F FS G+R C+G+ A + + +L+ +
Sbjct: 403 PNIF-KHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAF 461
Query: 277 RVSS 280
+ S
Sbjct: 462 SLES 465
>AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein.
Length = 504
Score = 78.6 bits (185), Expect = 3e-14
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 5/184 (2%)
Query: 100 GGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV 159
G F++K++ V ++FAG T+ST + L LL +P VQ V E+ R LG A +
Sbjct: 284 GTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG-AGQAP 342
Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGV-HQ 217
+ D RL Y +AVL E+ R+ + P+ I R + + YT P G+ LL + H
Sbjct: 343 SLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHD 402
Query: 218 HRIWGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
I+ ++F P+R+L+A F FS G+R C+G+ A + + +L+ +
Sbjct: 403 PNIF-KHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAF 461
Query: 277 RVSS 280
+ S
Sbjct: 462 SLES 465
>AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens
cDNA FLJ14699 fis, clone NT2RP2006571, moderately
similar to CYTOCHROME P450 2G1 (EC 1.14.14.1). ).
Length = 564
Score = 78.6 bits (185), Expect = 3e-14
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 5/184 (2%)
Query: 100 GGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV 159
G F++K++ V ++FAG T+ST + L LL +P VQ V E+ R LG A +
Sbjct: 284 GTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG-AGQAP 342
Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGV-HQ 217
+ D RL Y +AVL E+ R+ + P+ I R + + YT P G+ LL + H
Sbjct: 343 SLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHD 402
Query: 218 HRIWGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
I+ ++F P+R+L+A F FS G+R C+G+ A + + +L+ +
Sbjct: 403 PNIF-KHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAF 461
Query: 277 RVSS 280
+ S
Sbjct: 462 SLES 465
>AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1
protein.
Length = 504
Score = 78.6 bits (185), Expect = 3e-14
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 5/184 (2%)
Query: 100 GGAFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDV 159
G F++K++ V ++FAG T+ST + L LL +P VQ V E+ R LG A +
Sbjct: 284 GTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELG-AGQAP 342
Query: 160 TKEDYLRLEYLEAVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGV-HQ 217
+ D RL Y +AVL E+ R+ + P+ I R + + YT P G+ LL + H
Sbjct: 343 SLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHD 402
Query: 218 HRIWGADADQFRPERWLEA-ATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRY 276
I+ ++F P+R+L+A F FS G+R C+G+ A + + +L+ +
Sbjct: 403 PNIF-KHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAF 461
Query: 277 RVSS 280
+ S
Sbjct: 462 SLES 465
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 78.6 bits (185), Expect = 3e-14
Identities = 40/131 (30%), Positives = 74/131 (56%), Gaps = 1/131 (0%)
Query: 102 AFSDKDVREEVDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTK 161
A SD ++ + IIFA +DT ST L + L +HPDVQ K+ E+ VL + + VT
Sbjct: 289 ALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPN-KAPVTY 347
Query: 162 EDYLRLEYLEAVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIW 221
+ +++EYL+ V+ E++R++PV + R ++++ P G ++ ++ +H +
Sbjct: 348 DALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKY 407
Query: 222 GADADQFRPER 232
+ ++F PER
Sbjct: 408 WTEPEKFCPER 418
>U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 78.2 bits (184), Expect = 3e-14
Identities = 48/169 (28%), Positives = 83/169 (49%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ FAG +T+ST L LL HP+V+ KV+ E+ RV+G R ED ++ Y EAV
Sbjct: 297 NLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYTEAV 355
Query: 174 LKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R + P+ +A + + K +++ P G+ +L + + ++ P+
Sbjct: 356 IHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSELRDPRFFSNPQDCSPQH 415
Query: 233 WL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+L E F FS G+R C G+ A M + + +++ +R S
Sbjct: 416 FLDEKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKS 464
>K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein.
Length = 331
Score = 78.2 bits (184), Expect = 3e-14
Identities = 49/169 (28%), Positives = 83/169 (49%), Gaps = 3/169 (1%)
Query: 114 NIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLEAV 173
N+ G +T+ST L LL HP V+ KV+ E+ RV+G R ED ++ Y+EA+
Sbjct: 134 NLFIGGTETVSTTLRYGFLLLIKHPGVEAKVHEEIDRVIG-KNRQPKFEDRAKMPYMEAM 192
Query: 174 LKESMRMYPVAPVI-ARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPER 232
+ E R V P+I + K +++ P G+ +L V + I+ + F P+
Sbjct: 193 IHEIQRFGDVIPMIWPGRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPIFLSKPQDFNPQH 252
Query: 233 WLEAATLPDPS-FFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS 280
+ E P S F FS G+ +C G+ A M + + +++ +R+ S
Sbjct: 253 FTELEGAPKKSDAFVPFSIGQPNCFGEGLARMELFLFFTTVMQNFRLKS 301
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 78.2 bits (184), Expect = 3e-14
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
V ++ FAG +T ST L L +L +P++++K++ E+ RV+G + K D + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
AV+ E R + P + + + + Y P G+ + L V D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
E +L E +F FSTG+R C G+ A M + L +L+ + + V + L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471
Query: 290 EAI 292
I
Sbjct: 472 SPI 474
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 78.2 bits (184), Expect = 3e-14
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
V ++ FAG +T ST L L +L +P++++K++ E+ RV+G + K D + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
AV+ E R + P + + + + Y P G+ + L V D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
E +L E +F FSTG+R C G+ A M + L +L+ + + V + L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471
Query: 290 EAI 292
I
Sbjct: 472 SPI 474
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 78.2 bits (184), Expect = 3e-14
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
V ++ FAG +T ST L L +L +P++++K++ E+ RV+G + K D + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
AV+ E R + P + + + + Y P G+ + L V D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
E +L E +F FSTG+R C G+ A M + L +L+ + + V + L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471
Query: 290 EAI 292
I
Sbjct: 472 SPI 474
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 78.2 bits (184), Expect = 3e-14
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
V ++ FAG +T ST L L +L +P++++K++ E+ RV+G + K D + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
AV+ E R + P + + + + Y P G+ + L V D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
E +L E +F FSTG+R C G+ A M + L +L+ + + V + L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471
Query: 290 EAI 292
I
Sbjct: 472 SPI 474
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 78.2 bits (184), Expect = 3e-14
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
V ++ FAG +T ST L L +L +P++++K++ E+ RV+G + K D + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
AV+ E R + P + + + + Y P G+ + L V D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
E +L E +F FSTG+R C G+ A M + L +L+ + + V + L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471
Query: 290 EAI 292
I
Sbjct: 472 SPI 474
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 78.2 bits (184), Expect = 3e-14
Identities = 59/199 (29%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 116 IFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLE----YLE 171
+ AG++ I+ L+ A LL ++PD Q+K+ EV E+ + E + LE YL+
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVF---KEKHMAPE-FCSLEEGLPYLD 395
Query: 172 AVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPE 231
V+ E++RMYP A R + + ++ PAG+ + + +H + F PE
Sbjct: 396 MVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPE 455
Query: 232 RW-LEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS-DVTDLEFKL 289
R+ EA P + F G RSC+G ++ +K TL +L ++R + T + +L
Sbjct: 456 RFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQL 515
Query: 290 E--AILRPHRGHYIAIERR 306
E + L P G YI I R
Sbjct: 516 ESKSALGPKNGVYIKIVSR 534
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 78.2 bits (184), Expect = 3e-14
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
V ++ FAG +T ST L L +L +P++++K++ E+ RV+G + K D + Y++
Sbjct: 293 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 351
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
AV+ E R + P + + + + Y P G+ + L V D ++F+P
Sbjct: 352 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 411
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
E +L E +F FSTG+R C G+ A M + L +L+ + + V + L
Sbjct: 412 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 471
Query: 290 EAI 292
I
Sbjct: 472 SPI 474
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 78.2 bits (184), Expect = 3e-14
Identities = 50/183 (27%), Positives = 88/183 (48%), Gaps = 3/183 (1%)
Query: 112 VDNIIFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLEYLE 171
V ++ FAG +T ST L L +L +P++++K++ E+ RV+G + K D + Y++
Sbjct: 262 VADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIK-DRQEMPYMD 320
Query: 172 AVLKESMRMYPVAPV-IARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRP 230
AV+ E R + P + + + + Y P G+ + L V D ++F+P
Sbjct: 321 AVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKP 380
Query: 231 ERWL-EAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSSDVTDLEFKL 289
E +L E +F FSTG+R C G+ A M + L +L+ + + V + L
Sbjct: 381 EHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDL 440
Query: 290 EAI 292
I
Sbjct: 441 SPI 443
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 77.8 bits (183), Expect = 5e-14
Identities = 59/199 (29%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 116 IFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLE----YLE 171
+ AG++ I+ L+ A LL ++PD Q+K+ EV E+ + E + LE YL+
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVF---KEKHMAPE-FCSLEEGLPYLD 395
Query: 172 AVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPE 231
V+ E++RMYP A R + + ++ PAG+ + + +H + F PE
Sbjct: 396 MVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPENFNPE 455
Query: 232 RW-LEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS-DVTDLEFKL 289
R+ EA P + F G RSC+G ++ +K TL +L ++R + T + +L
Sbjct: 456 RFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQL 515
Query: 290 E--AILRPHRGHYIAIERR 306
E + L P G YI I R
Sbjct: 516 ESKSALGPKNGVYIKIVSR 534
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 77.4 bits (182), Expect = 6e-14
Identities = 59/199 (29%), Positives = 97/199 (48%), Gaps = 12/199 (6%)
Query: 116 IFAGHDTISTVLTTALSLLGSHPDVQDKVYNEVRRVLGDAERDVTKEDYLRLE----YLE 171
+ AG++ I+ L+ A LL ++PD Q+K+ EV E+ + E + LE YL+
Sbjct: 340 LIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVF---KEKHMAPE-FCSLEEGLPYLD 395
Query: 172 AVLKESMRMYPVAPVIARYSDAEVKLKNYTAPAGSGFILLLWGVHQHRIWGADADQFRPE 231
V+ E++RMYP A R + + ++ PAG+ + + +H + F PE
Sbjct: 396 MVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPE 455
Query: 232 RW-LEAATLPDPSFFAGFSTGRRSCIGKVYAMMSMKTTLSFLLRRYRVSS-DVTDLEFKL 289
R+ EA P + F G RSC+G ++ +K TL +L ++R + T + +L
Sbjct: 456 RFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQL 515
Query: 290 E--AILRPHRGHYIAIERR 306
E + L P G YI I R
Sbjct: 516 ESKSALGPKNGVYIKIVSR 534
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.135 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 43,133,013
Number of Sequences: 224733
Number of extensions: 1712603
Number of successful extensions: 4188
Number of sequences better than 10.0: 429
Number of HSP's better than 10.0 without gapping: 386
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 3092
Number of HSP's gapped (non-prelim): 457
length of query: 311
length of database: 73,234,838
effective HSP length: 90
effective length of query: 221
effective length of database: 53,008,868
effective search space: 11714959828
effective search space used: 11714959828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 65 (30.3 bits)
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