Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005449-TA|BGIBMGA005449-
PA|IPR004584|Recombination/repair protein Rad50, IPR003395|SMC
protein, N-terminal, IPR013134|Zinc hook, Rad50
(1199 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 442 e-123
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 437 e-121
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 437 e-121
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 437 e-121
BC108282-1|AAI08283.1| 723|Homo sapiens Unknown (protein for IM... 229 5e-59
BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein. 229 5e-59
BC062603-1|AAH62603.1| 557|Homo sapiens Unknown (protein for IM... 229 5e-59
BC140005-1|AAI40006.1| 110|Homo sapiens Unknown (protein for IM... 116 7e-25
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 81 2e-14
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 81 2e-14
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 81 2e-14
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 81 2e-14
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 81 3e-14
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 81 3e-14
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 78 2e-13
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 78 2e-13
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 78 2e-13
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 77 3e-13
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 77 3e-13
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 77 3e-13
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 77 4e-13
BC027860-1|AAH27860.1| 893|Homo sapiens filamin A interacting p... 76 9e-13
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 75 1e-12
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 75 1e-12
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 75 1e-12
U53445-1|AAA98972.1| 752|Homo sapiens DOC1 protein. 75 2e-12
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 74 3e-12
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 74 3e-12
AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein. 74 4e-12
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 73 5e-12
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 73 5e-12
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 73 5e-12
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 73 5e-12
AF155115-1|AAD42881.1| 472|Homo sapiens NY-REN-58 antigen protein. 71 2e-11
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 71 3e-11
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 71 3e-11
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 70 6e-11
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 70 6e-11
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 70 6e-11
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 70 6e-11
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 70 6e-11
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 70 6e-11
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 70 6e-11
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 69 1e-10
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 69 1e-10
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 68 2e-10
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 68 2e-10
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 68 2e-10
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 68 2e-10
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 68 2e-10
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 68 2e-10
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 67 4e-10
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 67 4e-10
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 66 7e-10
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 66 7e-10
BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein. 65 2e-09
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 64 2e-09
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 64 2e-09
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 64 2e-09
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 64 2e-09
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 64 2e-09
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 64 3e-09
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 64 3e-09
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 64 3e-09
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 64 3e-09
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 64 3e-09
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 64 4e-09
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 63 7e-09
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 63 7e-09
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 63 7e-09
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 63 7e-09
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 62 9e-09
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 62 1e-08
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 62 1e-08
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 62 1e-08
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 62 2e-08
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 62 2e-08
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 62 2e-08
BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein. 62 2e-08
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 62 2e-08
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 62 2e-08
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 61 2e-08
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 61 2e-08
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 61 2e-08
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 61 2e-08
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 61 2e-08
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 61 2e-08
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 61 2e-08
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 61 2e-08
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 61 3e-08
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 61 3e-08
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 61 3e-08
BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein. 61 3e-08
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 61 3e-08
AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein. 61 3e-08
AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein. 60 4e-08
AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein. 60 4e-08
AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envel... 60 4e-08
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 60 4e-08
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 60 5e-08
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 60 5e-08
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 60 6e-08
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 60 6e-08
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 60 6e-08
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 60 6e-08
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 60 6e-08
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 60 6e-08
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 60 6e-08
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 60 6e-08
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 60 6e-08
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 59 8e-08
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 59 8e-08
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 59 8e-08
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 59 8e-08
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 59 8e-08
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 59 8e-08
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 59 8e-08
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 59 1e-07
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 59 1e-07
BC125087-1|AAI25088.1| 568|Homo sapiens CCDC41 protein protein. 58 1e-07
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 58 1e-07
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 58 1e-07
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 58 2e-07
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 58 2e-07
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 58 3e-07
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 58 3e-07
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 58 3e-07
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 58 3e-07
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 58 3e-07
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 58 3e-07
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 58 3e-07
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 58 3e-07
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 58 3e-07
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 57 3e-07
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 57 3e-07
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 57 3e-07
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 57 3e-07
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 57 3e-07
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 57 3e-07
AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens ... 57 3e-07
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 57 3e-07
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 57 3e-07
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 57 4e-07
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 57 4e-07
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 57 4e-07
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 57 4e-07
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 57 4e-07
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 57 4e-07
AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein. 57 4e-07
AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein. 57 4e-07
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 56 6e-07
BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein pr... 56 6e-07
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 56 6e-07
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 56 6e-07
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 56 8e-07
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 56 8e-07
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 56 8e-07
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 56 8e-07
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 56 8e-07
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 56 8e-07
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 56 8e-07
AB046785-1|BAB13391.2| 1313|Homo sapiens KIAA1565 protein protein. 56 8e-07
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 56 8e-07
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 56 1e-06
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 56 1e-06
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 56 1e-06
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 56 1e-06
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 56 1e-06
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 56 1e-06
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 55 1e-06
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 55 1e-06
AF273042-1|AAG34902.1| 685|Homo sapiens CTCL tumor antigen se1-... 55 1e-06
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 55 2e-06
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 54 2e-06
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 54 2e-06
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 54 2e-06
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 54 2e-06
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 54 2e-06
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 54 2e-06
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 54 2e-06
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 54 3e-06
BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein. 54 3e-06
BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein. 54 3e-06
AL138742-1|CAI22698.1| 1325|Homo sapiens KIAA1009 protein. 54 3e-06
AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens ... 54 3e-06
AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein. 54 3e-06
AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein. 54 3e-06
AB023226-1|BAA76853.2| 1345|Homo sapiens KIAA1009 protein protein. 54 3e-06
AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein. 54 3e-06
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 54 4e-06
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 54 4e-06
AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,... 54 4e-06
AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,... 54 4e-06
AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens ... 54 4e-06
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 54 4e-06
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 53 5e-06
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 53 5e-06
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 53 5e-06
BC090932-1|AAH90932.1| 1377|Homo sapiens NIN protein protein. 53 5e-06
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 53 5e-06
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 53 5e-06
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 53 5e-06
BX537759-1|CAD97828.1| 1763|Homo sapiens hypothetical protein pr... 53 7e-06
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 53 7e-06
AL590642-2|CAH70770.1| 862|Homo sapiens CDK5 regulatory subunit... 53 7e-06
AL590642-1|CAH70769.1| 1893|Homo sapiens CDK5 regulatory subunit... 53 7e-06
AL391870-2|CAI40925.1| 1893|Homo sapiens CDK5 regulatory subunit... 53 7e-06
AL391870-1|CAI40926.1| 862|Homo sapiens CDK5 regulatory subunit... 53 7e-06
AL353736-2|CAI40654.1| 862|Homo sapiens CDK5 regulatory subunit... 53 7e-06
AL353736-1|CAI40653.1| 1893|Homo sapiens CDK5 regulatory subunit... 53 7e-06
AL138836-2|CAI16963.1| 1893|Homo sapiens CDK5 regulatory subunit... 53 7e-06
AL138836-1|CAI16964.1| 862|Homo sapiens CDK5 regulatory subunit... 53 7e-06
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 53 7e-06
AF448860-1|AAP41926.1| 1893|Homo sapiens hypothetical protein pr... 53 7e-06
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 52 9e-06
AF254756-1|AAK13079.1| 698|Homo sapiens predicted testis protei... 52 9e-06
AC019097-1|AAY14820.1| 698|Homo sapiens unknown protein. 52 9e-06
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 52 9e-06
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 52 1e-05
AY014284-1|AAK27309.1| 699|Homo sapiens nucleoporin NYD-SP7 pro... 52 1e-05
AL139095-7|CAI16451.1| 847|Homo sapiens cancer antigen 1 protein. 52 1e-05
AL139095-5|CAI16449.1| 545|Homo sapiens cancer antigen 1 protein. 52 1e-05
AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FH... 52 1e-05
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 52 1e-05
BX537708-1|CAD97819.1| 1605|Homo sapiens hypothetical protein pr... 52 2e-05
BX537421-1|CAD97663.1| 1204|Homo sapiens hypothetical protein pr... 52 2e-05
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 52 2e-05
BC028366-1|AAH28366.1| 698|Homo sapiens testis specific, 10 pro... 52 2e-05
AM177178-1|CAJ45482.1| 725|Homo sapiens kinesin-like protein KI... 52 2e-05
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 52 2e-05
AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein. 52 2e-05
AB046853-1|BAB13459.2| 1852|Homo sapiens KIAA1633 protein protein. 52 2e-05
Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of... 51 2e-05
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 51 2e-05
U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein. 51 2e-05
U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein. 51 2e-05
S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein. 51 2e-05
D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein. 51 2e-05
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 51 2e-05
BX537985-1|CAD97945.1| 1202|Homo sapiens hypothetical protein pr... 51 2e-05
BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural mainten... 51 2e-05
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 51 2e-05
BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein. 51 2e-05
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 51 2e-05
AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein. 51 2e-05
AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein. 51 2e-05
AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein. 51 2e-05
AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein. 51 2e-05
AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein. 51 2e-05
AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein. 51 2e-05
AY480045-1|AAR95678.1| 4533|Homo sapiens plectin 2 protein. 51 2e-05
AY480044-1|AAR95677.1| 4574|Homo sapiens plectin 1 protein. 51 2e-05
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 51 2e-05
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 51 2e-05
AL161779-1|CAI42089.1| 1233|Homo sapiens structural maintenance ... 51 2e-05
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 51 2e-05
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 51 2e-05
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 51 2e-05
AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2 ... 51 2e-05
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 51 3e-05
BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3 (Drosoph... 51 3e-05
BC048304-1|AAH48304.1| 597|Homo sapiens HOOK3 protein protein. 51 3e-05
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 51 3e-05
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 51 3e-05
AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated microt... 51 3e-05
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 51 3e-05
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 50 4e-05
BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein. 50 4e-05
BC108904-1|AAI08905.1| 725|Homo sapiens hyaluronan-mediated mot... 50 4e-05
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 50 4e-05
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 50 4e-05
AL590560-10|CAH71107.1| 551|Homo sapiens coiled-coil domain con... 50 4e-05
AL590431-11|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 50 4e-05
Z54367-1|CAA91196.1| 4684|Homo sapiens plectin protein. 50 5e-05
X69086-1|CAA48829.1| 3433|Homo sapiens utrophin (dystrophin rela... 50 5e-05
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 50 5e-05
BC008301-1|AAH08301.1| 390|Homo sapiens tuftelin 1 protein. 50 5e-05
BC007808-1|AAH07808.1| 1006|Homo sapiens MYH7B protein protein. 50 5e-05
BC002933-1|AAH02933.1| 365|Homo sapiens TUFT1 protein protein. 50 5e-05
AL590704-1|CAI10894.1| 3433|Homo sapiens utrophin (homologous to... 50 5e-05
AL590488-1|CAI16497.1| 3433|Homo sapiens utrophin (homologous to... 50 5e-05
AL513475-1|CAI13032.1| 3433|Homo sapiens utrophin (homologous to... 50 5e-05
AL513184-1|CAI40502.1| 3433|Homo sapiens utrophin (homologous to... 50 5e-05
AL365436-4|CAI16591.1| 390|Homo sapiens tuftelin 1 protein. 50 5e-05
AL365436-3|CAI16592.1| 365|Homo sapiens tuftelin 1 protein. 50 5e-05
AL357149-1|CAI40388.1| 3433|Homo sapiens utrophin (homologous to... 50 5e-05
AL024474-2|CAI23353.1| 3433|Homo sapiens utrophin (homologous to... 50 5e-05
AK223161-1|BAD96881.1| 390|Homo sapiens tuftelin 1 variant prot... 50 5e-05
AK128098-1|BAC87273.1| 1185|Homo sapiens protein ( Homo sapiens ... 50 5e-05
AK075001-1|BAC11346.1| 365|Homo sapiens protein ( Homo sapiens ... 50 5e-05
AF254860-1|AAF78914.1| 390|Homo sapiens tuftelin 1 protein. 50 5e-05
AF254260-1|AAF78913.1| 390|Homo sapiens tuftelin 1 protein. 50 5e-05
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 50 7e-05
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 50 7e-05
M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain alpha-... 50 7e-05
AL627308-5|CAH71336.1| 1732|Homo sapiens CDC42 binding protein k... 50 7e-05
AL627308-3|CAH71337.1| 1719|Homo sapiens CDC42 binding protein k... 50 7e-05
AL451047-3|CAH71185.1| 1732|Homo sapiens CDC42 binding protein k... 50 7e-05
AL451047-1|CAH71183.1| 1719|Homo sapiens CDC42 binding protein k... 50 7e-05
AL353689-9|CAI19109.1| 1732|Homo sapiens CDC42 binding protein k... 50 7e-05
AL353689-7|CAI19108.1| 1719|Homo sapiens CDC42 binding protein k... 50 7e-05
AJ518975-1|CAD57745.1| 1719|Homo sapiens CDC42 binding protein k... 50 7e-05
AF041853-1|AAC72294.1| 702|Homo sapiens kinesin family member p... 50 7e-05
AB208968-1|BAD92205.1| 1702|Homo sapiens CDC42 binding protein k... 50 7e-05
BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein. 49 9e-05
AK056465-1|BAB71192.1| 703|Homo sapiens protein ( Homo sapiens ... 49 9e-05
D87742-1|BAA13448.1| 1193|Homo sapiens KIAA0268 protein. 49 1e-04
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein. 49 1e-04
BC070281-1|AAH70281.1| 552|Homo sapiens HMMR protein protein. 49 1e-04
BC045542-1|AAH45542.1| 702|Homo sapiens KIF3A protein protein. 49 1e-04
AL592148-11|CAI40473.1| 785|Homo sapiens C219-reactive peptide ... 49 1e-04
AL592148-7|CAI40469.1| 1907|Homo sapiens C219-reactive peptide (... 49 1e-04
AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-... 49 1e-04
AF032862-1|AAC32548.1| 724|Homo sapiens intracellular hyaluroni... 49 1e-04
AB209780-1|BAD93017.1| 730|Homo sapiens Kinesin-like protein KI... 49 1e-04
D67035-1|BAA22586.1| 973|Homo sapiens SCP-1 protein. 48 2e-04
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 48 2e-04
BC057235-1|AAH57235.1| 613|Homo sapiens HMMR protein protein. 48 2e-04
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 48 2e-04
AK025628-1|BAB15194.1| 512|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AB040938-1|BAA96029.1| 693|Homo sapiens KIAA1505 protein protein. 48 2e-04
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 48 2e-04
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 48 2e-04
AK057222-1|BAB71385.1| 740|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AK023707-1|BAB14650.1| 435|Homo sapiens protein ( Homo sapiens ... 48 2e-04
AF272390-1|AAF78783.1| 1742|Homo sapiens myosin 5c protein. 48 2e-04
AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2... 48 2e-04
X65873-1|CAA46703.1| 963|Homo sapiens kinesin heavy chain protein. 48 3e-04
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 48 3e-04
BC126281-1|AAI26282.1| 963|Homo sapiens kinesin family member 5... 48 3e-04
BC126279-1|AAI26280.1| 963|Homo sapiens kinesin family member 5... 48 3e-04
BC113524-1|AAI13525.1| 578|Homo sapiens IFT74 protein protein. 48 3e-04
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 48 3e-04
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 48 3e-04
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 48 3e-04
AY040325-1|AAK77221.1| 600|Homo sapiens capillary morphogenesis... 48 3e-04
AL590431-12|CAH71270.1| 242|Homo sapiens tropomyosin 3 protein. 48 3e-04
AL356133-4|CAH72643.1| 600|Homo sapiens intraflagellar transpor... 48 3e-04
AL161932-2|CAH71618.1| 963|Homo sapiens kinesin family member 5... 48 3e-04
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 48 3e-04
AK092690-1|BAC03946.1| 243|Homo sapiens protein ( Homo sapiens ... 48 3e-04
AJ292348-1|CAC33883.1| 1478|Homo sapiens FYVE and coiled-coil do... 48 3e-04
AF414185-1|AAO47239.1| 641|Homo sapiens CAGE-1 protein. 48 3e-04
AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H1... 48 3e-04
AC093378-1|AAY15082.1| 659|Homo sapiens unknown protein. 48 3e-04
L16782-1|AAC37542.1| 566|Homo sapiens putative M phase phosphop... 47 4e-04
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 47 4e-04
BC101470-1|AAI01471.1| 1478|Homo sapiens FYVE and coiled-coil do... 47 4e-04
BC101468-1|AAI01469.1| 1478|Homo sapiens FYVE and coiled-coil do... 47 4e-04
BC089391-1|AAH89391.1| 466|Homo sapiens CCDC19 protein protein. 47 4e-04
BC064528-1|AAH64528.1| 762|Homo sapiens coiled-coil domain cont... 47 4e-04
BC051363-1|AAH51363.2| 729|Homo sapiens CTAGE family, member 5 ... 47 4e-04
BC034991-1|AAH34991.1| 495|Homo sapiens meiosis-specific nuclea... 47 4e-04
BC031046-1|AAH31046.1| 495|Homo sapiens meiosis-specific nuclea... 47 4e-04
AL451139-13|CAI15848.2| 762|Homo sapiens coiled-coil domain con... 47 4e-04
AL355877-2|CAH71540.2| 762|Homo sapiens coiled-coil domain cont... 47 4e-04
AL121586-4|CAB89415.1| 2442|Homo sapiens centrosomal protein 250... 47 4e-04
AK024038-1|BAB14794.1| 762|Homo sapiens protein ( Homo sapiens ... 47 4e-04
AK002084-1|BAA92077.1| 495|Homo sapiens protein ( Homo sapiens ... 47 4e-04
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 47 4e-04
AF049105-1|AAC07988.1| 2442|Homo sapiens centrosomal Nek2-associ... 47 4e-04
BC068997-1|AAH68997.1| 541|Homo sapiens centrosomal protein 63k... 47 5e-04
BC064355-1|AAH64355.1| 809|Homo sapiens CTAGE5 protein protein. 47 5e-04
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 47 5e-04
BC006984-1|AAH06984.1| 512|Homo sapiens Unknown (protein for IM... 47 5e-04
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 47 5e-04
AL391094-3|CAI23268.1| 785|Homo sapiens forkhead-associated (FH... 47 5e-04
AL158174-1|CAI21811.1| 785|Homo sapiens forkhead-associated (FH... 47 5e-04
AL031283-5|CAI21427.1| 785|Homo sapiens forkhead-associated (FH... 47 5e-04
AK057820-1|BAB71590.1| 273|Homo sapiens protein ( Homo sapiens ... 47 5e-04
AK023448-1|BAB14578.1| 541|Homo sapiens protein ( Homo sapiens ... 47 5e-04
AF092563-1|AAC72360.1| 1197|Homo sapiens chromosome-associated p... 47 5e-04
BC118918-1|AAI18919.1| 1302|Homo sapiens cingulin-like 1 protein. 46 6e-04
BC112049-1|AAI12050.1| 1302|Homo sapiens cingulin-like 1 protein. 46 6e-04
BC093827-1|AAH93827.1| 1302|Homo sapiens cingulin-like 1 protein. 46 6e-04
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 46 6e-04
BC033545-1|AAH33545.1| 700|Homo sapiens cancer antigen 1 protein. 46 6e-04
BC026194-1|AAH26194.1| 700|Homo sapiens cancer antigen 1 protein. 46 6e-04
AY651261-1|AAX35689.1| 1244|Homo sapiens centrosomal protein 1 p... 46 6e-04
AY274808-1|AAP42073.1| 1302|Homo sapiens KIAA1749 protein protein. 46 6e-04
AL451139-16|CAI15849.2| 434|Homo sapiens coiled-coil domain con... 46 6e-04
AL355877-3|CAH71541.2| 434|Homo sapiens coiled-coil domain cont... 46 6e-04
AK097760-1|BAC05162.1| 824|Homo sapiens protein ( Homo sapiens ... 46 6e-04
AB051536-1|BAB21840.2| 1047|Homo sapiens KIAA1749 protein protein. 46 6e-04
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 46 6e-04
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 46 8e-04
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 46 8e-04
CR769776-10|CAI95382.1| 354|Homo sapiens coiled-coil domain con... 46 8e-04
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 46 8e-04
L12579-1|AAA35654.1| 678|Homo sapiens protein ( Human alternati... 46 0.001
BX530088-1|CAI95784.1| 810|Homo sapiens GRIP1 associated protei... 46 0.001
BC036053-1|AAH36053.1| 955|Homo sapiens KIAA1505 protein protein. 46 0.001
AY131226-1|AAN07912.1| 681|Homo sapiens medulloblastoma antigen... 46 0.001
AK222832-1|BAD96552.1| 678|Homo sapiens CCAAT displacement prot... 46 0.001
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 46 0.001
AF312367-1|AAQ14554.1| 708|Homo sapiens La binding protein 1 pr... 46 0.001
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 46 0.001
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 45 0.001
BC101520-1|AAI01521.1| 1194|Homo sapiens protein tyrosine phosph... 45 0.001
BC101518-1|AAI01519.1| 1194|Homo sapiens protein tyrosine phosph... 45 0.001
BC080185-1|AAH80185.1| 417|Homo sapiens SMC1A protein protein. 45 0.001
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein. 45 0.001
AB058696-1|BAB47422.1| 1270|Homo sapiens KIAA1793 protein protein. 45 0.001
AB014554-1|BAA31629.2| 1267|Homo sapiens KIAA0654 protein protein. 45 0.001
U22816-1|AAC50173.1| 1202|Homo sapiens LAR-interacting protein 1... 45 0.002
U22815-1|AAC50172.1| 1185|Homo sapiens LAR-interacting protein 1... 45 0.002
S67240-1|AAB28951.1| 330|Homo sapiens smooth muscle myosin heav... 45 0.002
S67238-1|AAB28950.1| 296|Homo sapiens smooth muscle myosin heav... 45 0.002
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 45 0.002
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 45 0.002
BC051733-1|AAH51733.1| 1026|Homo sapiens LUZP1 protein protein. 45 0.002
BC034046-1|AAH34046.1| 1202|Homo sapiens protein tyrosine phosph... 45 0.002
AL591543-1|CAI17285.1| 992|Homo sapiens ankyrin repeat domain 1... 45 0.002
AL031428-1|CAI19705.1| 1026|Homo sapiens leucine zipper protein ... 45 0.002
AF094758-1|AAD55817.1| 386|Homo sapiens nasopharyngeal epitheli... 45 0.002
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 45 0.002
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 45 0.002
Z99496-1|CAI21605.1| 805|Homo sapiens chromosome 6 open reading... 44 0.002
X63105-1|CAA44819.1| 726|Homo sapiens Tpr protein. 44 0.002
BC094764-1|AAH94764.1| 692|Homo sapiens TPR protein protein. 44 0.002
BC016514-1|AAH16514.1| 687|Homo sapiens TPR protein protein. 44 0.002
AL589993-1|CAI16048.1| 805|Homo sapiens chromosome 6 open readi... 44 0.002
AL390069-1|CAI14134.1| 805|Homo sapiens chromosome 6 open readi... 44 0.002
AF308284-1|AAG48252.1| 546|Homo sapiens serologically defined b... 44 0.002
X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for ... 44 0.003
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 44 0.003
BX664727-6|CAI39536.1| 823|Homo sapiens ankyrin repeat domain 2... 44 0.003
BX649567-4|CAI94992.1| 259|Homo sapiens novel protein protein. 44 0.003
BC130385-1|AAI30386.1| 1197|Homo sapiens structural maintenance ... 44 0.003
BC101026-1|AAI01027.1| 490|Homo sapiens SASS6 protein protein. 44 0.003
BC066592-1|AAH66592.1| 1516|Homo sapiens CUTL1 protein protein. 44 0.003
BC025422-1|AAH25422.1| 676|Homo sapiens cut-like 1, CCAAT displ... 44 0.003
AY359522-1|AAQ57128.1| 657|Homo sapiens hypothetical protein DK... 44 0.003
AL834265-1|CAD38940.1| 505|Homo sapiens hypothetical protein pr... 44 0.003
AL773545-6|CAI12706.1| 823|Homo sapiens ankyrin repeat domain 2... 44 0.003
AL445928-1|CAH72248.1| 657|Homo sapiens novel protein protein. 44 0.003
AL354938-1|CAI16923.1| 1197|Homo sapiens structural maintenance ... 44 0.003
AL161791-1|CAI16866.1| 1197|Homo sapiens structural maintenance ... 44 0.003
AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 44 0.003
AK131470-1|BAD18615.1| 458|Homo sapiens protein ( Homo sapiens ... 44 0.003
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 44 0.003
AK056673-1|BAB71249.1| 883|Homo sapiens protein ( Homo sapiens ... 44 0.003
AB046821-1|BAB13427.1| 690|Homo sapiens KIAA1601 protein protein. 44 0.003
BX640704-1|CAE45824.1| 594|Homo sapiens hypothetical protein pr... 44 0.004
BX530088-3|CAI95786.1| 841|Homo sapiens GRIP1 associated protei... 44 0.004
BX530088-2|CAI95785.1| 796|Homo sapiens GRIP1 associated protei... 44 0.004
BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein. 44 0.004
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 44 0.004
BC101546-1|AAI01547.1| 841|Homo sapiens GRIP1 associated protei... 44 0.004
BC101544-1|AAI01545.1| 841|Homo sapiens GRIP1 associated protei... 44 0.004
BC001522-1|AAH01522.2| 557|Homo sapiens GRIPAP1 protein protein. 44 0.004
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 44 0.004
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 44 0.004
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 44 0.004
AL031283-7|CAI21429.1| 647|Homo sapiens forkhead-associated (FH... 44 0.004
AF034799-1|AAC26100.1| 1257|Homo sapiens liprin-alpha2 protein. 44 0.004
AB032993-1|BAA86481.1| 834|Homo sapiens KIAA1167 protein protein. 44 0.004
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 44 0.004
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 44 0.004
L06148-1|AAA35921.1| 579|Homo sapiens golgin-165 protein. 43 0.006
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 43 0.006
BX649567-2|CAH71137.1| 823|Homo sapiens ankyrin repeat domain 2... 43 0.006
BC104912-1|AAI04913.1| 1236|Homo sapiens PPFIA2 protein protein. 43 0.006
BC077732-1|AAH77732.1| 662|Homo sapiens FKBP15 protein protein. 43 0.006
BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for IM... 43 0.006
BC031242-1|AAH31242.1| 446|Homo sapiens coiled-coil domain cont... 43 0.006
AY736182-1|AAU86898.1| 1989|Homo sapiens ninein isoform 6 protein. 43 0.006
AK027816-1|BAB55389.1| 436|Homo sapiens protein ( Homo sapiens ... 43 0.006
AF535142-1|AAN03486.1| 8749|Homo sapiens enaptin protein. 43 0.006
AF495910-1|AAN60442.1| 8797|Homo sapiens nesprin-1 protein. 43 0.006
AF302773-1|AAG33512.2| 2090|Homo sapiens ninein-Lm isoform protein. 43 0.006
AB210009-1|BAE06091.1| 1258|Homo sapiens PPFIA2 variant protein ... 43 0.006
CR769776-11|CAI95383.1| 823|Homo sapiens ankyrin repeat domain ... 43 0.008
BX640896-1|CAE45944.1| 1359|Homo sapiens hypothetical protein pr... 43 0.008
BC038515-1|AAH38515.1| 796|Homo sapiens CCDC110 protein protein. 43 0.008
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 43 0.008
BC028419-1|AAH28419.1| 833|Homo sapiens coiled-coil domain cont... 43 0.008
BC014050-1|AAH14050.1| 495|Homo sapiens centrosomal protein 63k... 43 0.008
AY610514-1|AAT37906.1| 1302|Homo sapiens paracingulin protein. 43 0.008
AL136382-1|CAI23513.1| 620|Homo sapiens novel protein protein. 43 0.008
AK127744-1|BAC87110.1| 600|Homo sapiens protein ( Homo sapiens ... 43 0.008
AK098636-1|BAC05359.1| 412|Homo sapiens protein ( Homo sapiens ... 43 0.008
AK093883-1|BAC04242.1| 600|Homo sapiens protein ( Homo sapiens ... 43 0.008
AK057305-1|BAB71418.1| 399|Homo sapiens protein ( Homo sapiens ... 43 0.008
AF200415-1|AAF08305.2| 1825|Homo sapiens proliferation-related p... 43 0.008
AB080722-1|BAC81776.1| 833|Homo sapiens hypothetical protein pr... 43 0.008
S78388-1|AAB20813.1| 443|Homo sapiens autoantigen recognized by... 42 0.010
M63256-1|AAA51961.1| 509|Homo sapiens major Yo paraneoplastic a... 42 0.010
D12981-1|BAA02360.1| 443|Homo sapiens paraneoplastic cerebellar... 42 0.010
D11393-1|BAA01989.1| 208|Homo sapiens human non-muscle myosin h... 42 0.010
BX530088-4|CAI95787.1| 625|Homo sapiens GRIP1 associated protei... 42 0.010
BC054006-1|AAH54006.1| 762|Homo sapiens EPS15 protein protein. 42 0.010
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 42 0.010
BC017503-1|AAH17503.2| 454|Homo sapiens cerebellar degeneration... 42 0.010
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 42 0.010
AL671986-10|CAI13031.1| 762|Homo sapiens epidermal growth facto... 42 0.010
AL513478-3|CAH72532.1| 823|Homo sapiens ankyrin repeat domain 2... 42 0.010
AK023738-1|BAB14662.1| 475|Homo sapiens protein ( Homo sapiens ... 42 0.010
AF092564-1|AAC72361.1| 1202|Homo sapiens chromosome-associated p... 42 0.010
AB019987-1|BAA73535.1| 1288|Homo sapiens chromosome-associated p... 42 0.010
>Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50
protein.
Length = 1318
Score = 442 bits (1088), Expect = e-123
Identities = 265/1012 (26%), Positives = 495/1012 (48%), Gaps = 19/1012 (1%)
Query: 188 SDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S+ ++++K+ + + L L N+ TV+ K+++L D +++ NKE + EKS
Sbjct: 293 SELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSEL 352
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAENATKTILEKVES 305
+E + L ++QE I R+ I A E++ +E + +N K + E+ E
Sbjct: 353 LVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEG 412
Query: 306 -LKSDHKVQKSQADEEEKKAQGFVDECRSGHT---QXXXXXXXXXXXXXXXXXXXXXDIT 361
K+ +++ A++E K Q +DE R T + ++
Sbjct: 413 EAKTANQLMNDFAEKETLK-QKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQ 471
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
S +AE N+E + E+ + ++ + +L Q++
Sbjct: 472 QLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEM 531
Query: 422 TKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE 481
+L T + EM+ ++ K++Q+ +K++H L LLG P K + +
Sbjct: 532 EQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK---QLEDWLHS 588
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
E+ E + HI L + +L+ EDK++ CG+Q ++ L
Sbjct: 589 KSKEINQTRDRLAKLNKELASSEQNKNHINNELERKEEQLSSYEDKLFDVCGSQDFESDL 648
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN--SCCPLCNRGFENESEXXXXXXXXX 599
+ +EK ++ +L + + +++ QL D SCCP+C R F+ E+E
Sbjct: 649 DRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEAISDLQ 708
Query: 600 XXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIK 659
P KL+ +L++ ++DE+L + + + I LK+ EIP+L ++ +V+ I+
Sbjct: 709 SKLRLAPDKLKSTESELKKKEKRRDEMLGLAPMRQSIIDLKEKEIPELRNKLQNVNRDIQ 768
Query: 660 TLNETVEE--ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
L +EE + I PE++ +AK D+ +++R+ E+K V +K + +D
Sbjct: 769 RLKNDIEEQETLLGTIMPEEE--SAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGID 826
Query: 718 SEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
+ T+ ++ + + K+ T+ ++++ +K + +++Q L + K E L
Sbjct: 827 LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTN 886
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG 837
+Q LEE +L ++ ++PLE L++ + K E++ + +
Sbjct: 887 LQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIA 946
Query: 838 SAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
+ ++ + +I+ H + M++ + +K++ + + ++ + +
Sbjct: 947 QDKLNDIKEKVKNIHGYMKDIENHIQDGKDDYMKQKETELNKVIAQLSECEKHKEKINED 1006
Query: 898 IDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL-NEKESL 956
+ ++ +I Q++ +R L DNL LRK ++ +++ + +++ + ++ +E + L
Sbjct: 1007 MRLMRQDIDTQKIQERWLQDNLTLRKRNEELKEVEEEGKQHLKEMGQMQVLQMKSEHQKL 1066
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
+ + G ++ + F+ EL + +D E+K+RE M + T+ ++KD
Sbjct: 1067 EENIDNIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRTTELVNKD 1126
Query: 1017 IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEG--NLTVESERR 1074
+ Y LD+ +M+FH KME IN IIR+LWR YRG DI+YIEI+++ N++ +RR
Sbjct: 1127 LDIYYKTLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENVSASDKRR 1186
Query: 1075 KYDYRVVQSKNGVEIDMRGRCSAGQKVLACLIIRLALAETFSSRFGILALDEPTTNLDQE 1134
Y+YRVV K +DMRGRCSAGQKVLA LIIRLALAETF GI+ALDEPTTNLD+E
Sbjct: 1187 NYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGIIALDEPTTNLDRE 1246
Query: 1135 NIHSLCAALGEIVQERMMQKNFMFIIITHDKEFIESLGNIDKVTHYYEVSRN 1186
NI SL AL EI++ R Q+NF ++ITHD++F+E LG + V +Y + +N
Sbjct: 1247 NIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRIKKN 1298
Score = 224 bits (548), Expect = 1e-57
Identities = 131/350 (37%), Positives = 205/350 (58%), Gaps = 28/350 (8%)
Query: 7 LAIRGIRSFGPEDTDEQRILFDSPLTLILGQNGCGKTTIIECLRYAITGQMPPGSRNECF 66
++I G+RSFG ED D+Q I F SPLT+++G NG GKTTIIECL+Y TG PPG++ F
Sbjct: 13 MSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPGTKGNTF 72
Query: 67 VHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESG 126
VHD KV + T+V Q++L+ + + + V RSM V KKT+F+TL+ + T + G
Sbjct: 73 VHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSM-VCTQKSKKTEFKTLEGVI-TRTKHG 130
Query: 127 KTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADK 186
+ +SS+CA++D M LGVSKA+LN+V+FCHQEDS+WPL EGK +K++FDEIF A +
Sbjct: 131 EKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDEIFSATR 190
Query: 187 YSDCLDRLKKIR-------KDYAQNLKLLENY-------ATTVKAKQKELEDSYKKNTSF 232
Y L+ L+++R ++Y LK L+ Y + +K+ +L S + S+
Sbjct: 191 YIKALETLRQVRQTQGQKVEEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSY 250
Query: 233 NKEEEKIANEKSSNEIEYNKFILLESQNQEK-IDKRNEQIVE-----TAKIAEIENITEV 286
E + + N EIE+N +++ N+ K +D R +Q+ + K+ ++ T+
Sbjct: 251 ENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDE 308
Query: 287 QTNEEAENATKTILEKVESLKSDH----KVQKSQADEEEKKAQGFVDECR 332
Q N+ N +T+ EK L H K+ K ++K++ V++ R
Sbjct: 309 QLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGR 358
Score = 45.6 bits (103), Expect = 0.001
Identities = 80/441 (18%), Positives = 193/441 (43%), Gaps = 31/441 (7%)
Query: 610 EKVTEDLQRASAKKDEILS----MKSLNEKITTLKDT--EIPQLEKRIVDVDTQIKTLNE 663
EK E + ++K+ ++ S +KS ++ LK+ EI +I+ +D +IK L+
Sbjct: 224 EKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDS 283
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTL 722
+++ E E+KM Q D + D Y +TV +K + + +++
Sbjct: 284 RKKQMEKDNSELEEKMEKVFQ-GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKES 342
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL--------YEKKTKAKEELLNT 774
+ ++ + + L+ + Q+ + A + +Q+L +E+ ++ ++ N
Sbjct: 343 RLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNF 402
Query: 775 QKKVQDIVNLE-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
K V++ E ++ QL +D I + L IE K+E++ + ++
Sbjct: 403 HKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE 462
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
++ + ++E + +++ LD E I+ ++ + + ++ +++ Q + D
Sbjct: 463 LKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNE-KADLD 521
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD--ITNWQ-KQDDELNEKLNGI-NKE 948
+K+D +++ + + + L KA D I + + DEL L NK+
Sbjct: 522 RTLRKLDQEMEQLNHHTTTRTQM-EMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK 580
Query: 949 ELNE---KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
+L + +S I QT+ + A+ L+ +++ NELE+ ++ + +K++
Sbjct: 581 QLEDWLHSKSKEINQTR--DRLAKLNKELASSEQNKNHINNELER--KEEQLSSYEDKLF 636
Query: 1006 ELHVTKAIDKDIREYAVALDK 1026
++ ++ + D+ ++K
Sbjct: 637 DVCGSQDFESDLDRLKEEIEK 657
>U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein.
Length = 1312
Score = 437 bits (1076), Expect = e-121
Identities = 276/1019 (27%), Positives = 500/1019 (49%), Gaps = 33/1019 (3%)
Query: 188 SDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S+ ++++K+ + + L L N+ TV+ K+++L D +++ NKE + EKS
Sbjct: 287 SELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSEL 346
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAENATKTILEKVES 305
+E + L ++QE I R+ I A E++ +E + +N K + E+ E
Sbjct: 347 LVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEG 406
Query: 306 -LKSDHKVQKSQADEEEKKAQGFVDECRSGHT---QXXXXXXXXXXXXXXXXXXXXXDIT 361
K+ +++ A++E K Q +DE R T + ++
Sbjct: 407 EAKTANQLMNDFAEKETLK-QKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQ 465
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
S +AE N+E + E+ + ++ + +L Q++
Sbjct: 466 QLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEM 525
Query: 422 TKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE 481
+L T + EM+ ++ K++Q+ +K++H L LLG P K + +
Sbjct: 526 EQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK---QLEDWLHS 582
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
E+ E + HI L + +L+ EDK++ CG+Q ++ L
Sbjct: 583 KSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDL 642
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN--SCCPLCNRGFENESEXXXXXXXXX 599
+ +EK ++ +L + + +++ QL D SCCP+C R F+ E+E
Sbjct: 643 DRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQ 702
Query: 600 XXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIK 659
P KL+ +L++ ++DE+L + + + I LK+ EIP+L ++ +V+ I+
Sbjct: 703 SKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNRDIQ 762
Query: 660 TLNETVEE--ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
L +EE + I PE++ +AK D+ +++R+ E+K V +K + +D
Sbjct: 763 RLKNDIEEQETLLGTIMPEEE--SAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGID 820
Query: 718 SEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
+ T+ ++ + + K+ T+ ++++ +K + +++Q L + K E L
Sbjct: 821 LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTN 880
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR----NRDL 833
+Q LEE +L ++ ++PLE L++ + K E++ + N+
Sbjct: 881 LQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIA 940
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAEIQQHK---KKNVPREMEKIQEANDKLMEKQKQIMTD 890
+ + KV+ +K ++ IQ K KK E+ K+ + + +++I D
Sbjct: 941 QDKLNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINED 1000
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
+++ + IDT Q++ +R L DNL LRK ++ +++ + +++ + ++
Sbjct: 1001 MRLMRQDIDT-------QKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQM 1053
Query: 951 -NEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
+E + L + + G ++ + F+ EL + +D E+K+RE M +
Sbjct: 1054 KSEHQKLEENIDNIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRT 1113
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEG--NL 1067
T+ ++KD+ Y LD+ +M+FH KME IN IIR+LWR YRG DI+YIEI+++ N+
Sbjct: 1114 TELVNKDLDIYYKTLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENV 1173
Query: 1068 TVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACLIIRLALAETFSSRFGILALDEP 1127
+ +RR Y+YRVV K +DMRGRCSAGQKVLA LIIRLALAETF GI+ALDEP
Sbjct: 1174 SASDKRRNYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGIIALDEP 1233
Query: 1128 TTNLDQENIHSLCAALGEIVQERMMQKNFMFIIITHDKEFIESLGNIDKVTHYYEVSRN 1186
TTNLD+ENI SL AL EI++ R Q+NF ++ITHD++F+E LG + V +Y + +N
Sbjct: 1234 TTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRIKKN 1292
Score = 229 bits (560), Expect = 5e-59
Identities = 133/356 (37%), Positives = 209/356 (58%), Gaps = 28/356 (7%)
Query: 1 MAGVKSLAIRGIRSFGPEDTDEQRILFDSPLTLILGQNGCGKTTIIECLRYAITGQMPPG 60
M+ ++ ++I G+RSFG ED D+Q I F SPLT+++G NG GKTTIIECL+Y TG PPG
Sbjct: 1 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG 60
Query: 61 SRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLS 120
++ FVHD KV + T+V Q++L+ + + + V RSM V KKT+F+TL+ +
Sbjct: 61 TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSM-VCTQKSKKTEFKTLEGVI- 118
Query: 121 TVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDE 180
T + G+ +SS+CA++D M LGVSKA+LN+V+FCHQEDS+WPL EGK +K++FDE
Sbjct: 119 TRTKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDE 178
Query: 181 IFDADKYSDCLDRLKKIR-------KDYAQNLKLLENY-------ATTVKAKQKELEDSY 226
IF A +Y L+ L+++R K+Y LK L+ Y + +K+ +L S
Sbjct: 179 IFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSK 238
Query: 227 KKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEK-IDKRNEQIVE-----TAKIAEI 280
+ S+ E + + N EIE+N +++ N+ K +D R +Q+ + K+ ++
Sbjct: 239 EIVKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKV 296
Query: 281 ENITEVQTNEEAENATKTILEKVESLKSDH----KVQKSQADEEEKKAQGFVDECR 332
T+ Q N+ N +T+ EK L H K+ K ++K++ V++ R
Sbjct: 297 FQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGR 352
Score = 44.0 bits (99), Expect = 0.003
Identities = 79/441 (17%), Positives = 193/441 (43%), Gaps = 31/441 (7%)
Query: 610 EKVTEDLQRASAKKDEILS----MKSLNEKITTLKDT--EIPQLEKRIVDVDTQIKTLNE 663
EK E + ++K+ ++ S +KS ++ LK+ EI +I+ +D +IK L+
Sbjct: 218 EKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDS 277
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTL 722
+++ E E+KM Q D + D Y +TV +K + + +++
Sbjct: 278 RKKQMEKDNSELEEKMEKVFQ-GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKES 336
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL--------YEKKTKAKEELLNT 774
+ ++ + + L+ + Q+ + A + +Q+L +E+ ++ ++ N
Sbjct: 337 RLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNF 396
Query: 775 QKKVQDIVNLE-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
K V++ E ++ QL +D I + L IE K+E++ + ++
Sbjct: 397 HKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE 456
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
++ + ++E + +++ LD E I+ ++ + + ++ +++ Q + D
Sbjct: 457 LKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNE-KADLD 515
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD--ITNWQ-KQDDELNEKLNGI-NKE 948
+K+D +++ + + + L KA D I + + DEL L NK+
Sbjct: 516 RTLRKLDQEMEQLNHHTTTRTQM-EMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK 574
Query: 949 ELNE---KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
+L + +S I QT+ + A+ L+ +++ NEL++ ++ + +K++
Sbjct: 575 QLEDWLHSKSKEINQTR--DRLAKLNKELASSEQNKNHINNELKR--KEEQLSSYEDKLF 630
Query: 1006 ELHVTKAIDKDIREYAVALDK 1026
++ ++ + D+ ++K
Sbjct: 631 DVCGSQDFESDLDRLKEEIEK 651
>AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein
protein.
Length = 1173
Score = 437 bits (1076), Expect = e-121
Identities = 276/1019 (27%), Positives = 500/1019 (49%), Gaps = 33/1019 (3%)
Query: 188 SDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S+ ++++K+ + + L L N+ TV+ K+++L D +++ NKE + EKS
Sbjct: 148 SELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSEL 207
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAENATKTILEKVES 305
+E + L ++QE I R+ I A E++ +E + +N K + E+ E
Sbjct: 208 LVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEG 267
Query: 306 -LKSDHKVQKSQADEEEKKAQGFVDECRSGHT---QXXXXXXXXXXXXXXXXXXXXXDIT 361
K+ +++ A++E K Q +DE R T + ++
Sbjct: 268 EAKTANQLMNDFAEKETLK-QKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQ 326
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
S +AE N+E + E+ + ++ + +L Q++
Sbjct: 327 QLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEM 386
Query: 422 TKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE 481
+L T + EM+ ++ K++Q+ +K++H L LLG P K + +
Sbjct: 387 EQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK---QLEDWLHS 443
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
E+ E + HI L + +L+ EDK++ CG+Q ++ L
Sbjct: 444 KSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDL 503
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN--SCCPLCNRGFENESEXXXXXXXXX 599
+ +EK ++ +L + + +++ QL D SCCP+C R F+ E+E
Sbjct: 504 DRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQ 563
Query: 600 XXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIK 659
P KL+ +L++ ++DE+L + + + I LK+ EIP+L ++ +V+ I+
Sbjct: 564 SKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNRDIQ 623
Query: 660 TLNETVEE--ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
L +EE + I PE++ +AK D+ +++R+ E+K V +K + +D
Sbjct: 624 RLKNDIEEQETLLGTIMPEEE--SAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGID 681
Query: 718 SEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
+ T+ ++ + + K+ T+ ++++ +K + +++Q L + K E L
Sbjct: 682 LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTN 741
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR----NRDL 833
+Q LEE +L ++ ++PLE L++ + K E++ + N+
Sbjct: 742 LQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIA 801
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAEIQQHK---KKNVPREMEKIQEANDKLMEKQKQIMTD 890
+ + KV+ +K ++ IQ K KK E+ K+ + + +++I D
Sbjct: 802 QDKLNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINED 861
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
+++ + IDT Q++ +R L DNL LRK ++ +++ + +++ + ++
Sbjct: 862 MRLMRQDIDT-------QKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQM 914
Query: 951 -NEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
+E + L + + G ++ + F+ EL + +D E+K+RE M +
Sbjct: 915 KSEHQKLEENIDNIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRT 974
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEG--NL 1067
T+ ++KD+ Y LD+ +M+FH KME IN IIR+LWR YRG DI+YIEI+++ N+
Sbjct: 975 TELVNKDLDIYYKTLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENV 1034
Query: 1068 TVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACLIIRLALAETFSSRFGILALDEP 1127
+ +RR Y+YRVV K +DMRGRCSAGQKVLA LIIRLALAETF GI+ALDEP
Sbjct: 1035 SASDKRRNYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGIIALDEP 1094
Query: 1128 TTNLDQENIHSLCAALGEIVQERMMQKNFMFIIITHDKEFIESLGNIDKVTHYYEVSRN 1186
TTNLD+ENI SL AL EI++ R Q+NF ++ITHD++F+E LG + V +Y + +N
Sbjct: 1095 TTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRIKKN 1153
Score = 105 bits (251), Expect = 1e-21
Identities = 70/215 (32%), Positives = 115/215 (53%), Gaps = 26/215 (12%)
Query: 142 MHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIR--- 198
M LGVSKA+LN+V+FCHQEDS+WPL EGK +K++FDEIF A +Y L+ L+++R
Sbjct: 1 MISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQ 60
Query: 199 ----KDYAQNLKLLENY-------ATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNE 247
K+Y LK L+ Y + +K+ +L S + S+ E + + N E
Sbjct: 61 GQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNR--LKE 118
Query: 248 IEYNKFILLESQNQEK-IDKRNEQIVE-----TAKIAEIENITEVQTNEEAENATKTILE 301
IE+N +++ N+ K +D R +Q+ + K+ ++ T+ Q N+ N +T+ E
Sbjct: 119 IEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLYHNHQRTVRE 178
Query: 302 KVESLKSDH----KVQKSQADEEEKKAQGFVDECR 332
K L H K+ K ++K++ V++ R
Sbjct: 179 KERKLVDCHRELEKLNKESRLLNQEKSELLVEQGR 213
Score = 44.0 bits (99), Expect = 0.003
Identities = 79/441 (17%), Positives = 193/441 (43%), Gaps = 31/441 (7%)
Query: 610 EKVTEDLQRASAKKDEILS----MKSLNEKITTLKDT--EIPQLEKRIVDVDTQIKTLNE 663
EK E + ++K+ ++ S +KS ++ LK+ EI +I+ +D +IK L+
Sbjct: 79 EKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDS 138
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTL 722
+++ E E+KM Q D + D Y +TV +K + + +++
Sbjct: 139 RKKQMEKDNSELEEKMEKVFQ-GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKES 197
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL--------YEKKTKAKEELLNT 774
+ ++ + + L+ + Q+ + A + +Q+L +E+ ++ ++ N
Sbjct: 198 RLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNF 257
Query: 775 QKKVQDIVNLE-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
K V++ E ++ QL +D I + L IE K+E++ + ++
Sbjct: 258 HKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE 317
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
++ + ++E + +++ LD E I+ ++ + + ++ +++ Q + D
Sbjct: 318 LKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNE-KADLD 376
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD--ITNWQ-KQDDELNEKLNGI-NKE 948
+K+D +++ + + + L KA D I + + DEL L NK+
Sbjct: 377 RTLRKLDQEMEQLNHHTTTRTQM-EMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK 435
Query: 949 ELNE---KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
+L + +S I QT+ + A+ L+ +++ NEL++ ++ + +K++
Sbjct: 436 QLEDWLHSKSKEINQTR--DRLAKLNKELASSEQNKNHINNELKR--KEEQLSSYEDKLF 491
Query: 1006 ELHVTKAIDKDIREYAVALDK 1026
++ ++ + D+ ++K
Sbjct: 492 DVCGSQDFESDLDRLKEEIEK 512
>AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein.
Length = 1312
Score = 437 bits (1076), Expect = e-121
Identities = 276/1019 (27%), Positives = 500/1019 (49%), Gaps = 33/1019 (3%)
Query: 188 SDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S+ ++++K+ + + L L N+ TV+ K+++L D +++ NKE + EKS
Sbjct: 287 SELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSEL 346
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAENATKTILEKVES 305
+E + L ++QE I R+ I A E++ +E + +N K + E+ E
Sbjct: 347 LVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEG 406
Query: 306 -LKSDHKVQKSQADEEEKKAQGFVDECRSGHT---QXXXXXXXXXXXXXXXXXXXXXDIT 361
K+ +++ A++E K Q +DE R T + ++
Sbjct: 407 EAKTANQLMNDFAEKETLK-QKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQ 465
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
S +AE N+E + E+ + ++ + +L Q++
Sbjct: 466 QLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEM 525
Query: 422 TKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE 481
+L T + EM+ ++ K++Q+ +K++H L LLG P K + +
Sbjct: 526 EQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK---QLEDWLHS 582
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
E+ E + HI L + +L+ EDK++ CG+Q ++ L
Sbjct: 583 KSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDL 642
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN--SCCPLCNRGFENESEXXXXXXXXX 599
+ +EK ++ +L + + +++ QL D SCCP+C R F+ E+E
Sbjct: 643 DRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQ 702
Query: 600 XXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIK 659
P KL+ +L++ ++DE+L + + + I LK+ EIP+L ++ +V+ I+
Sbjct: 703 SKLRLAPDKLKSTESELKKKEKRRDEMLGLVPMRQSIIDLKEKEIPELRNKLQNVNRDIQ 762
Query: 660 TLNETVEE--ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
L +EE + I PE++ +AK D+ +++R+ E+K V +K + +D
Sbjct: 763 RLKNDIEEQETLLGTIMPEEE--SAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGID 820
Query: 718 SEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
+ T+ ++ + + K+ T+ ++++ +K + +++Q L + K E L
Sbjct: 821 LDRTVQQVNQEKQEKQHKLDTVSSKIELNRKLIQDQQEQIQHLKSTTNELKSEKLQISTN 880
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR----NRDL 833
+Q LEE +L ++ ++PLE L++ + K E++ + N+
Sbjct: 881 LQRRQQLEEQTVELSTEVQSLYREIKDAKEQVSPLETTLEKFQQEKEELINKKNTSNKIA 940
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAEIQQHK---KKNVPREMEKIQEANDKLMEKQKQIMTD 890
+ + KV+ +K ++ IQ K KK E+ K+ + + +++I D
Sbjct: 941 QDKLNDIKEKVKNIHGYMKDIENYIQDGKDDYKKQKETELNKVIAQLSECEKHKEKINED 1000
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
+++ + IDT Q++ +R L DNL LRK ++ +++ + +++ + ++
Sbjct: 1001 MRLMRQDIDT-------QKIQERWLQDNLTLRKRNEELKEVEEERKQHLKEMGQMQVLQM 1053
Query: 951 -NEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
+E + L + + G ++ + F+ EL + +D E+K+RE M +
Sbjct: 1054 KSEHQKLEENIDNIKRNHNLALGRQKGYEEEIIHFKKELREPQFRDAEEKYREMMIVMRT 1113
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEG--NL 1067
T+ ++KD+ Y LD+ +M+FH KME IN IIR+LWR YRG DI+YIEI+++ N+
Sbjct: 1114 TELVNKDLDIYYKTLDQAIMKFHSMKMEEINKIIRDLWRSTYRGQDIEYIEIRSDADENV 1173
Query: 1068 TVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACLIIRLALAETFSSRFGILALDEP 1127
+ +RR Y+YRVV K +DMRGRCSAGQKVLA LIIRLALAETF GI+ALDEP
Sbjct: 1174 SASDKRRNYNYRVVMLKGDTALDMRGRCSAGQKVLASLIIRLALAETFCLNCGIIALDEP 1233
Query: 1128 TTNLDQENIHSLCAALGEIVQERMMQKNFMFIIITHDKEFIESLGNIDKVTHYYEVSRN 1186
TTNLD+ENI SL AL EI++ R Q+NF ++ITHD++F+E LG + V +Y + +N
Sbjct: 1234 TTNLDRENIESLAHALVEIIKSRSQQRNFQLLVITHDEDFVELLGRSEYVEKFYRIKKN 1292
Score = 229 bits (560), Expect = 5e-59
Identities = 133/356 (37%), Positives = 209/356 (58%), Gaps = 28/356 (7%)
Query: 1 MAGVKSLAIRGIRSFGPEDTDEQRILFDSPLTLILGQNGCGKTTIIECLRYAITGQMPPG 60
M+ ++ ++I G+RSFG ED D+Q I F SPLT+++G NG GKTTIIECL+Y TG PPG
Sbjct: 1 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG 60
Query: 61 SRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLS 120
++ FVHD KV + T+V Q++L+ + + + V RSM V KKT+F+TL+ +
Sbjct: 61 TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSM-VCTQKSKKTEFKTLEGVI- 118
Query: 121 TVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDE 180
T + G+ +SS+CA++D M LGVSKA+LN+V+FCHQEDS+WPL EGK +K++FDE
Sbjct: 119 TRTKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDE 178
Query: 181 IFDADKYSDCLDRLKKIR-------KDYAQNLKLLENY-------ATTVKAKQKELEDSY 226
IF A +Y L+ L+++R K+Y LK L+ Y + +K+ +L S
Sbjct: 179 IFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSK 238
Query: 227 KKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEK-IDKRNEQIVE-----TAKIAEI 280
+ S+ E + + N EIE+N +++ N+ K +D R +Q+ + K+ ++
Sbjct: 239 EIVKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKV 296
Query: 281 ENITEVQTNEEAENATKTILEKVESLKSDH----KVQKSQADEEEKKAQGFVDECR 332
T+ Q N+ N +T+ EK L H K+ K ++K++ V++ R
Sbjct: 297 FQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGR 352
Score = 44.0 bits (99), Expect = 0.003
Identities = 79/441 (17%), Positives = 193/441 (43%), Gaps = 31/441 (7%)
Query: 610 EKVTEDLQRASAKKDEILS----MKSLNEKITTLKDT--EIPQLEKRIVDVDTQIKTLNE 663
EK E + ++K+ ++ S +KS ++ LK+ EI +I+ +D +IK L+
Sbjct: 218 EKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDS 277
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTL 722
+++ E E+KM Q D + D Y +TV +K + + +++
Sbjct: 278 RKKQMEKDNSELEEKMEKVFQ-GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKES 336
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL--------YEKKTKAKEELLNT 774
+ ++ + + L+ + Q+ + A + +Q+L +E+ ++ ++ N
Sbjct: 337 RLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNF 396
Query: 775 QKKVQDIVNLE-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
K V++ E ++ QL +D I + L IE K+E++ + ++
Sbjct: 397 HKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE 456
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
++ + ++E + +++ LD E I+ ++ + + ++ +++ Q + D
Sbjct: 457 LKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNE-KADLD 515
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD--ITNWQ-KQDDELNEKLNGI-NKE 948
+K+D +++ + + + L KA D I + + DEL L NK+
Sbjct: 516 RTLRKLDQEMEQLNHHTTTRTQM-EMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK 574
Query: 949 ELNE---KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
+L + +S I QT+ + A+ L+ +++ NEL++ ++ + +K++
Sbjct: 575 QLEDWLHSKSKEINQTR--DRLAKLNKELASSEQNKNHINNELKR--KEEQLSSYEDKLF 630
Query: 1006 ELHVTKAIDKDIREYAVALDK 1026
++ ++ + D+ ++K
Sbjct: 631 DVCGSQDFESDLDRLKEEIEK 651
>BC108282-1|AAI08283.1| 723|Homo sapiens Unknown (protein for
IMAGE:3855371) protein.
Length = 723
Score = 229 bits (560), Expect = 5e-59
Identities = 133/356 (37%), Positives = 209/356 (58%), Gaps = 28/356 (7%)
Query: 1 MAGVKSLAIRGIRSFGPEDTDEQRILFDSPLTLILGQNGCGKTTIIECLRYAITGQMPPG 60
M+ ++ ++I G+RSFG ED D+Q I F SPLT+++G NG GKTTIIECL+Y TG PPG
Sbjct: 1 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG 60
Query: 61 SRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLS 120
++ FVHD KV + T+V Q++L+ + + + V RSM V KKT+F+TL+ +
Sbjct: 61 TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSM-VCTQKSKKTEFKTLEGVI- 118
Query: 121 TVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDE 180
T + G+ +SS+CA++D M LGVSKA+LN+V+FCHQEDS+WPL EGK +K++FDE
Sbjct: 119 TRTKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDE 178
Query: 181 IFDADKYSDCLDRLKKIR-------KDYAQNLKLLENY-------ATTVKAKQKELEDSY 226
IF A +Y L+ L+++R K+Y LK L+ Y + +K+ +L S
Sbjct: 179 IFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSK 238
Query: 227 KKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEK-IDKRNEQIVE-----TAKIAEI 280
+ S+ E + + N EIE+N +++ N+ K +D R +Q+ + K+ ++
Sbjct: 239 EIVKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKV 296
Query: 281 ENITEVQTNEEAENATKTILEKVESLKSDH----KVQKSQADEEEKKAQGFVDECR 332
T+ Q N+ N +T+ EK L H K+ K ++K++ V++ R
Sbjct: 297 FQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGR 352
Score = 124 bits (299), Expect = 2e-27
Identities = 93/439 (21%), Positives = 183/439 (41%), Gaps = 12/439 (2%)
Query: 188 SDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S+ ++++K+ + + L L N+ TV+ K+++L D +++ NKE + EKS
Sbjct: 287 SELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSEL 346
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAENATKTILEKVES 305
+E + L ++QE I R+ I A E++ +E + +N K + E+ E
Sbjct: 347 LVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEG 406
Query: 306 -LKSDHKVQKSQADEEEKKAQGFVDECRSGHT---QXXXXXXXXXXXXXXXXXXXXXDIT 361
K+ +++ A++E K Q +DE R T + ++
Sbjct: 407 EAKTANQLMNDFAEKETLK-QKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQ 465
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
S +AE N+E + E+ + ++ + +L Q++
Sbjct: 466 QLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEM 525
Query: 422 TKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE 481
+L T + EM+ ++ K++Q+ +K++H L LLG P K + +
Sbjct: 526 EQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK---QLEDWLHS 582
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
E+ E + HI L + +L+ EDK++ CG+Q ++ L
Sbjct: 583 KSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDL 642
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXX 599
+ +EK ++ +L + + +++ QL D SCCP+C R F+ E+E
Sbjct: 643 DRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQ 702
Query: 600 XXXMNVPGKLEKVTEDLQR 618
P KL+ +L++
Sbjct: 703 SKLRLAPDKLKSTESELKK 721
Score = 44.0 bits (99), Expect = 0.003
Identities = 79/441 (17%), Positives = 193/441 (43%), Gaps = 31/441 (7%)
Query: 610 EKVTEDLQRASAKKDEILS----MKSLNEKITTLKDT--EIPQLEKRIVDVDTQIKTLNE 663
EK E + ++K+ ++ S +KS ++ LK+ EI +I+ +D +IK L+
Sbjct: 218 EKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDS 277
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTL 722
+++ E E+KM Q D + D Y +TV +K + + +++
Sbjct: 278 RKKQMEKDNSELEEKMEKVFQ-GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKES 336
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL--------YEKKTKAKEELLNT 774
+ ++ + + L+ + Q+ + A + +Q+L +E+ ++ ++ N
Sbjct: 337 RLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNF 396
Query: 775 QKKVQDIVNLE-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
K V++ E ++ QL +D I + L IE K+E++ + ++
Sbjct: 397 HKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE 456
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
++ + ++E + +++ LD E I+ ++ + + ++ +++ Q + D
Sbjct: 457 LKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNE-KADLD 515
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD--ITNWQ-KQDDELNEKLNGI-NKE 948
+K+D +++ + + + L KA D I + + DEL L NK+
Sbjct: 516 RTLRKLDQEMEQLNHHTTTRTQM-EMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK 574
Query: 949 ELNE---KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
+L + +S I QT+ + A+ L+ +++ NEL++ ++ + +K++
Sbjct: 575 QLEDWLHSKSKEINQTR--DRLAKLNKELASSEQNKNHINNELKR--KEEQLSSYEDKLF 630
Query: 1006 ELHVTKAIDKDIREYAVALDK 1026
++ ++ + D+ ++K
Sbjct: 631 DVCGSQDFESDLDRLKEEIEK 651
>BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein.
Length = 723
Score = 229 bits (560), Expect = 5e-59
Identities = 133/356 (37%), Positives = 209/356 (58%), Gaps = 28/356 (7%)
Query: 1 MAGVKSLAIRGIRSFGPEDTDEQRILFDSPLTLILGQNGCGKTTIIECLRYAITGQMPPG 60
M+ ++ ++I G+RSFG ED D+Q I F SPLT+++G NG GKTTIIECL+Y TG PPG
Sbjct: 1 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG 60
Query: 61 SRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLS 120
++ FVHD KV + T+V Q++L+ + + + V RSM V KKT+F+TL+ +
Sbjct: 61 TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSM-VCTQKSKKTEFKTLEGVI- 118
Query: 121 TVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDE 180
T + G+ +SS+CA++D M LGVSKA+LN+V+FCHQEDS+WPL EGK +K++FDE
Sbjct: 119 TRTKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDE 178
Query: 181 IFDADKYSDCLDRLKKIR-------KDYAQNLKLLENY-------ATTVKAKQKELEDSY 226
IF A +Y L+ L+++R K+Y LK L+ Y + +K+ +L S
Sbjct: 179 IFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSK 238
Query: 227 KKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEK-IDKRNEQIVE-----TAKIAEI 280
+ S+ E + + N EIE+N +++ N+ K +D R +Q+ + K+ ++
Sbjct: 239 EIVKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKV 296
Query: 281 ENITEVQTNEEAENATKTILEKVESLKSDH----KVQKSQADEEEKKAQGFVDECR 332
T+ Q N+ N +T+ EK L H K+ K ++K++ V++ R
Sbjct: 297 FQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGR 352
Score = 124 bits (299), Expect = 2e-27
Identities = 93/439 (21%), Positives = 183/439 (41%), Gaps = 12/439 (2%)
Query: 188 SDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S+ ++++K+ + + L L N+ TV+ K+++L D +++ NKE + EKS
Sbjct: 287 SELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSEL 346
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAENATKTILEKVES 305
+E + L ++QE I R+ I A E++ +E + +N K + E+ E
Sbjct: 347 LVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEG 406
Query: 306 -LKSDHKVQKSQADEEEKKAQGFVDECRSGHT---QXXXXXXXXXXXXXXXXXXXXXDIT 361
K+ +++ A++E K Q +DE R T + ++
Sbjct: 407 EAKTANQLMNDFAEKETLK-QKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQ 465
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
S +AE N+E + E+ + ++ + +L Q++
Sbjct: 466 QLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEM 525
Query: 422 TKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE 481
+L T + EM+ ++ K++Q+ +K++H L LLG P K + +
Sbjct: 526 EQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK---QLEDWLHS 582
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
E+ E + HI L + +L+ EDK++ CG+Q ++ L
Sbjct: 583 KSKEINQTRDRLAKLNKELASSEQNKNHINNELKRKEEQLSSYEDKLFDVCGSQDFESDL 642
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXX 599
+ +EK ++ +L + + +++ QL D SCCP+C R F+ E+E
Sbjct: 643 DRLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEVISDLQ 702
Query: 600 XXXMNVPGKLEKVTEDLQR 618
P KL+ +L++
Sbjct: 703 SKLRLAPDKLKSTESELKK 721
Score = 44.0 bits (99), Expect = 0.003
Identities = 79/441 (17%), Positives = 193/441 (43%), Gaps = 31/441 (7%)
Query: 610 EKVTEDLQRASAKKDEILS----MKSLNEKITTLKDT--EIPQLEKRIVDVDTQIKTLNE 663
EK E + ++K+ ++ S +KS ++ LK+ EI +I+ +D +IK L+
Sbjct: 218 EKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDS 277
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTL 722
+++ E E+KM Q D + D Y +TV +K + + +++
Sbjct: 278 RKKQMEKDNSELEEKMEKVFQ-GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKES 336
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL--------YEKKTKAKEELLNT 774
+ ++ + + L+ + Q+ + A + +Q+L +E+ ++ ++ N
Sbjct: 337 RLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNF 396
Query: 775 QKKVQDIVNLE-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
K V++ E ++ QL +D I + L IE K+E++ + ++
Sbjct: 397 HKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE 456
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
++ + ++E + +++ LD E I+ ++ + + ++ +++ Q + D
Sbjct: 457 LKNVKYELQQLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNE-KADLD 515
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD--ITNWQ-KQDDELNEKLNGI-NKE 948
+K+D +++ + + + L KA D I + + DEL L NK+
Sbjct: 516 RTLRKLDQEMEQLNHHTTTRTQM-EMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK 574
Query: 949 ELNE---KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
+L + +S I QT+ + A+ L+ +++ NEL++ ++ + +K++
Sbjct: 575 QLEDWLHSKSKEINQTR--DRLAKLNKELASSEQNKNHINNELKR--KEEQLSSYEDKLF 630
Query: 1006 ELHVTKAIDKDIREYAVALDK 1026
++ ++ + D+ ++K
Sbjct: 631 DVCGSQDFESDLDRLKEEIEK 651
>BC062603-1|AAH62603.1| 557|Homo sapiens Unknown (protein for
IMAGE:5493315) protein.
Length = 557
Score = 229 bits (560), Expect = 5e-59
Identities = 133/356 (37%), Positives = 209/356 (58%), Gaps = 28/356 (7%)
Query: 1 MAGVKSLAIRGIRSFGPEDTDEQRILFDSPLTLILGQNGCGKTTIIECLRYAITGQMPPG 60
M+ ++ ++I G+RSFG ED D+Q I F SPLT+++G NG GKTTIIECL+Y TG PPG
Sbjct: 1 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG 60
Query: 61 SRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLS 120
++ FVHD KV + T+V Q++L+ + + + V RSM V KKT+F+TL+ +
Sbjct: 61 TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSM-VCTQKSKKTEFKTLEGVI- 118
Query: 121 TVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDE 180
T + G+ +SS+CA++D M LGVSKA+LN+V+FCHQEDS+WPL EGK +K++FDE
Sbjct: 119 TRTKHGEKVSLSSKCAEIDREMISSLGVSKAVLNNVIFCHQEDSNWPLSEGKALKQKFDE 178
Query: 181 IFDADKYSDCLDRLKKIR-------KDYAQNLKLLENY-------ATTVKAKQKELEDSY 226
IF A +Y L+ L+++R K+Y LK L+ Y + +K+ +L S
Sbjct: 179 IFSATRYIKALETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSK 238
Query: 227 KKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEK-IDKRNEQIVE-----TAKIAEI 280
+ S+ E + + N EIE+N +++ N+ K +D R +Q+ + K+ ++
Sbjct: 239 EIVKSYENELDPLKNR--LKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKV 296
Query: 281 ENITEVQTNEEAENATKTILEKVESLKSDH----KVQKSQADEEEKKAQGFVDECR 332
T+ Q N+ N +T+ EK L H K+ K ++K++ V++ R
Sbjct: 297 FQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGR 352
Score = 57.6 bits (133), Expect = 3e-07
Identities = 53/267 (19%), Positives = 112/267 (41%), Gaps = 7/267 (2%)
Query: 188 SDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S+ ++++K+ + + L L N+ TV+ K+++L D +++ NKE + EKS
Sbjct: 287 SELEEKMEKVFQGTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSEL 346
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAENATKTILEKVE- 304
+E + L ++QE I R+ I A E++ +E + +N K + E+ E
Sbjct: 347 LVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEG 406
Query: 305 SLKSDHKVQKSQADEEEKKAQGFVDECR---SGHTQXXXXXXXXXXXXXXXXXXXXXDIT 361
K+ +++ A++E K Q +DE R +G + ++
Sbjct: 407 EAKTANQLMNDFAEKETLK-QKQIDEIRDKKTGLGRIIELKSEILSKKQNELKNVKYELQ 465
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
S +AE N+E + E+ + ++ + +L Q++
Sbjct: 466 QLEGSSDRILELDQELIKAERELSKAEKNSNVETLKMEVISLQNEKADLDRTLRKLDQEM 525
Query: 422 TKLQKQTAKLKEKEMIEENLKTKEKQL 448
+L T + EM+ ++ K++Q+
Sbjct: 526 EQLNHHTTTRTQMEMLTKDKADKDEQI 552
Score = 37.1 bits (82), Expect = 0.38
Identities = 50/265 (18%), Positives = 117/265 (44%), Gaps = 17/265 (6%)
Query: 610 EKVTEDLQRASAKKDEILS----MKSLNEKITTLKDT--EIPQLEKRIVDVDTQIKTLNE 663
EK E + ++K+ ++ S +KS ++ LK+ EI +I+ +D +IK L+
Sbjct: 218 EKACEIRDQITSKEAQLTSSKEIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALDS 277
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTL 722
+++ E E+KM Q D + D Y +TV +K + + +++
Sbjct: 278 RKKQMEKDNSELEEKMEKVFQ-GTDEQLNDLYHNHQRTVREKERKLVDCHRELEKLNKES 336
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL--------YEKKTKAKEELLNT 774
+ ++ + + L+ + Q+ + A + +Q+L +E+ ++ ++ N
Sbjct: 337 RLLNQEKSELLVEQGRLQLQADRHQEHIRARDSLIQSLATQLELDGFERGPFSERQIKNF 396
Query: 775 QKKVQDIVNLE-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
K V++ E ++ QL +D I + L IE K+E++ + ++
Sbjct: 397 HKLVRERQEGEAKTANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE 456
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAEI 858
++ + ++E + +++ LD E+
Sbjct: 457 LKNVKYELQQLEGSSDRILELDQEL 481
Score = 34.7 bits (76), Expect = 2.0
Identities = 56/270 (20%), Positives = 111/270 (41%), Gaps = 16/270 (5%)
Query: 736 ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDC 795
+ TLR +T +K+ + +L+ L + K KA E K + + +E K +++
Sbjct: 189 LETLRQVRQTQGQKVKEYQMELKYLKQYKEKACEIRDQITSKEAQLTSSKEIVKSYENEL 248
Query: 796 X---XXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV- 851
I L+ +K K ++ + N +L E + N +
Sbjct: 249 DPLKNRLKEIEHNLSKIMKLDNEIKALDSRKKQMEKDNSELEEKMEKVFQGTDEQLNDLY 308
Query: 852 KSLDAEIQQHKKKNVP--REMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQE 909
+ +++ ++K V RE+EK+ + + L +++ +++ ++ L + D ++ I ++
Sbjct: 309 HNHQRTVREKERKLVDCHRELEKLNKESRLLNQEKSELLVEQGRLQLQADRHQEHIRARD 368
Query: 910 VYKRDLDDNLCLRK------AQTDITNWQKQDDELNE---KLNGINKEELNEKESLIIKQ 960
+ L L L ++ I N+ K E E K + EKE+L KQ
Sbjct: 369 SLIQSLATQLELDGFERGPFSERQIKNFHKLVRERQEGEAKTANQLMNDFAEKETLKQKQ 428
Query: 961 TKLFQQKAECTGALSELKKS-LKGFRNELE 989
+ K G + ELK L +NEL+
Sbjct: 429 IDEIRDKKTGLGRIIELKSEILSKKQNELK 458
>BC140005-1|AAI40006.1| 110|Homo sapiens Unknown (protein for
IMAGE:8860357) protein.
Length = 110
Score = 116 bits (278), Expect = 7e-25
Identities = 53/109 (48%), Positives = 75/109 (68%)
Query: 1 MAGVKSLAIRGIRSFGPEDTDEQRILFDSPLTLILGQNGCGKTTIIECLRYAITGQMPPG 60
M+ ++ ++I G+RSFG ED D+Q I F SPLT+++G NG GKTTIIECL+Y TG PPG
Sbjct: 1 MSRIEKMSILGVRSFGIEDKDKQIITFFSPLTILVGPNGAGKTTIIECLKYICTGDFPPG 60
Query: 61 SRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKK 109
++ FVHD KV + T+V Q++L+ + + + V RSM T +KKK
Sbjct: 61 TKGNTFVHDPKVAQETDVRAQIRLQFRDVNGELIAVQRSMVCTQKSKKK 109
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 81.0 bits (191), Expect = 2e-14
Identities = 203/1048 (19%), Positives = 417/1048 (39%), Gaps = 88/1048 (8%)
Query: 69 DAKVNRSTEVLGQVKLKIVNAK-DKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGK 127
D K N + Q +L+++ + KQ E+ K A+ K+ +T D L+ V+E K
Sbjct: 1072 DLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDR-LAEVEEKLK 1130
Query: 128 TKDVSSRCADLDIL-MHEELGVSKAILNSVVFCHQEDSSWPL----------DEGKKVKE 176
K + +L + EE+ + +N + E + L + +K+ E
Sbjct: 1131 EKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNE 1190
Query: 177 RFDEIFDADKYSDCLDRLKKIRKDYAQNLK--LLENYATTVKAKQKELEDSY---KKNTS 231
++E+ K L L+K + +L+ + E AT ++ K+ EL+ ++ K++
Sbjct: 1191 NYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE-ELKIAHIHLKEHQE 1249
Query: 232 FNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQ---IVETAKIAEI-ENITEVQ 287
E + +EK++ I ++ QE+I +E+ + K++E E + E++
Sbjct: 1250 TIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELE 1309
Query: 288 T-NEEAENATKTILEKVES--LKSDHKVQKSQAD-----EEEKKAQGFVDECRSGHTQXX 339
E++ T L ++E L+ + K Q+SQ + +E + + H Q
Sbjct: 1310 LLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLK 1369
Query: 340 XXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQE 399
+ + E+ + +
Sbjct: 1370 EHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKR 1429
Query: 400 INEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE--KEMIEENLKTKEKQLIV---LKNK 454
+ E ++ +E D+L + LQ ++ +LKE KE++ ++L+T+E+ + LK +
Sbjct: 1430 LQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ 1489
Query: 455 HKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESL 514
+T + EL N+ EK+ ++ + + E N+ ++ + ++E++
Sbjct: 1490 EET-INELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQLNIK-QISEVQENV 1547
Query: 515 NERRS--ELTKAEDKIYKACGTQPYDVT--LSKYTTTVEKLQDEQNVLQSSMFIINKYKG 570
NE + E KA+D ++ ++ ++T L + ++ + E+ ++ + +
Sbjct: 1548 NELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERD 1607
Query: 571 QLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKV-----TEDLQRASAKKDE 625
QLK+N+ + E E ++E + T+ L + + +
Sbjct: 1608 QLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETEN 1667
Query: 626 ILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT--LNETVEE-ITMSLIEPEQKMTTA 682
I + L+E + ++ + + R V+ +++ L E + E IT L + E+
Sbjct: 1668 IRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVH 1727
Query: 683 KQIHGDMPMLDRY-------IQEIKTVTKKFE----AVKEQCGDVDSEMTLDVATAKQ-- 729
+ +D+ EI + K E A+K Q + E+ + K+
Sbjct: 1728 MHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQ 1787
Query: 730 --VD-FKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKA------KEELLNTQKKVQ 779
+D + +S +++ QK L N KLQ + E K K+++ TQKKV
Sbjct: 1788 ETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVS 1847
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN-RDLIEAGS 838
+ +E+ KKQ++ L L+E E R N R + E
Sbjct: 1848 E---MEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKE--RDNLRRVEETLK 1902
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+++ + + K+ D EIQQ + K ++ +E DKL EK + + K +
Sbjct: 1903 LERDQLKESLQETKARDLEIQQ-ELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDL 1961
Query: 899 DTLKDEIAK--QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
D KDE+ K QE+ K++L L + + D+ K+ +E+ + L + E
Sbjct: 1962 DKSKDELQKKIQELQKKELQ----LLRVKEDVNMSHKKINEMEQLKKQFEPNYLCKCEMD 2017
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
+ TK + E +++ + L+ + L+ + I RE + + +
Sbjct: 2018 NFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFI-ATLREMIARDRQNHQVKPE 2076
Query: 1017 IREYAVALDKCLMEFHREKMENINMIIR 1044
R + + LME REK I +++
Sbjct: 2077 KRLLSDG-QQHLMESLREKCSRIKELLK 2103
Score = 77.0 bits (181), Expect = 4e-13
Identities = 147/733 (20%), Positives = 301/733 (41%), Gaps = 64/733 (8%)
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
AE E ++E Q++ E ++ + ++EM E+ +KI +++ +LK KE+ E+++T+
Sbjct: 1123 AEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERL 1182
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINK-FECEVRNEVXXXXXXXXXXXXXXXXLEA 505
+L N++ E+ E+ + K FE E + L+
Sbjct: 1183 ELAQKLNEN---YEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKI 1239
Query: 506 ERKHIRESLNERRSELTKA-EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL------ 558
H++E E EL ++ +K + TQ + + +K + L +EQ +L
Sbjct: 1240 AHIHLKEH-QETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKV 1298
Query: 559 ---QSSMFIINKYKGQ--LKDNSCCP-------LCNRGFENESEXXXXXXXXXXXXMNVP 606
Q +M + Q KD++ N F+ E +
Sbjct: 1299 SETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIK 1358
Query: 607 GKLE----KVTEDLQRASAKKDEILSM--KSLNEKITTLKDTEIPQLEKRIVDVDTQIKT 660
LE ++ E ++ AK E S +SLN K + T+I ++ D+ +
Sbjct: 1359 EALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLR 1418
Query: 661 LNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE-QCGDVDSE 719
+ + ++ L E +M + + D+ L +Q K E +KE +++E
Sbjct: 1419 IEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLK--ENIKEIVAKHLETE 1476
Query: 720 MTLDVATAKQVDFKQKISTLR-------NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
L VA + ++ I+ LR + T QK+L A N KLQ + + KEE L
Sbjct: 1477 EELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQ-EIYEKEEQL 1535
Query: 773 NTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
N K++ ++ KQ + + L L+E E +++ +
Sbjct: 1536 NI-KQISEVQENVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEE 1594
Query: 833 LIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP-REMEKIQEANDKL--MEKQKQIMT 889
+ A + + K + A++++ ++K +M + E +K+ +E K+
Sbjct: 1595 MKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFE 1654
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQK----QDDELNEKLNGI 945
+++ + I+T + I ++ +L++ + K + D+ + ++ + D+L E L
Sbjct: 1655 TQKLNLENIET--ENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRET 1712
Query: 946 NKEELNEKESLIIKQTKLFQQKA---ECTGALSELKKSLKGFRNELEKS--LSKDIEKKF 1000
+L ++E L I L + + + G +SE + + +LE S K + K
Sbjct: 1713 ITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKI 1772
Query: 1001 REKMYELHV-----TKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGND 1055
+E++ H+ + IDK + DK + ++ +EN N ++E +++ + N+
Sbjct: 1773 QEELRIAHMHLKEQQETIDKLRGIVSEKTDK--LSNMQKDLENSNAKLQEKIQEL-KANE 1829
Query: 1056 IDYIEIKTEGNLT 1068
I +K + N T
Sbjct: 1830 HQLITLKKDVNET 1842
Score = 68.1 bits (159), Expect = 2e-10
Identities = 166/982 (16%), Positives = 407/982 (41%), Gaps = 64/982 (6%)
Query: 88 NAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELG 147
+ KD ++ + + K+ +L ++K + Q + S + E + K ++ I EEL
Sbjct: 1032 DVKDNEI-IEQQRKIFSLIQEKNELQQM--LESVIAEKEQLKTDLKENIEMTIENQEEL- 1087
Query: 148 VSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKL 207
+L + QE + ++ +K+ + D+ ++ ++LK+ + + +
Sbjct: 1088 ---RLLGDELKKQQEIVAQ--EKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQ 1142
Query: 208 LENYATTVKAKQKELEDSYK-KNTSFNKEE--EKIANEKS--SNEIEYNKFILLESQNQE 262
L N + QK++ + KN NKE E + E+ + ++ N + +
Sbjct: 1143 LLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKER 1202
Query: 263 KIDKRNEQIVETAK------IAEIENITEVQTNEEAENA---TKTILEKVESLK---SDH 310
K+ K ++ ET + I EIE T +QT EE + A K E ++ L+ S+
Sbjct: 1203 KVLKELQKSFETERDHLRGYIREIE-ATGLQTKEELKIAHIHLKEHQETIDELRRSVSEK 1261
Query: 311 KVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXX 370
Q + EK +E H + +T + +
Sbjct: 1262 TAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKKVSETQETMNELELLTEQSTTKDST 1321
Query: 371 XXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK 430
K E++ I+ +E + + E E + D+L + I + + +
Sbjct: 1322 TLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQE 1381
Query: 431 LKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXX 490
+ K+ N+K K+ + + ++ + + + + + ++K E +E+
Sbjct: 1382 SQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVA 1441
Query: 491 XXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVE 549
L++E ++E++ E ++ + E+++ A C + + T+++ +
Sbjct: 1442 KEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLS 1501
Query: 550 KLQDEQNVLQSSMFIIN-KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN--VP 606
+ + E + +Q + IN K + ++++ +E E + +N
Sbjct: 1502 EKETEISTIQKQLEAINDKLQNKIQEI---------YEKEEQLNIKQISEVQENVNELKQ 1552
Query: 607 GKLEKVTED--LQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
K + +D LQ +K E+ + +++ + E ++++ + + L E
Sbjct: 1553 FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKEN 1612
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSE-MTLD 723
+EI + E ++K ++ ++ + EI+ + ++FE K ++++E + L
Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTAVNETQEK-MCEIEHLKEQFETQKLNLENIETENIRLT 1671
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
+ ++ + ++ R+ +++ ++ L +L K +E + +K +++
Sbjct: 1672 QILHENLEEMRSVTKERDDLRSVEETLKVERDQL------KENLRETITRDLEKQEELKI 1725
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
+ K+ Q I+ ++ L+ +A + ++ + ++ +
Sbjct: 1726 VHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKE 1785
Query: 844 VEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQI-MTDRQVLT--KKIDT 900
+ +K++ + +E + K N+ +++E +N KL EK +++ + Q++T K ++
Sbjct: 1786 QQETIDKLRGIVSE-KTDKLSNMQKDLE---NSNAKLQEKIQELKANEHQLITLKKDVNE 1841
Query: 901 LKDEIAKQEVYKRDL-DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELN---EKESL 956
+ ++++ E K+ + D +L L K + + N ++ E E++ + KE N +E+L
Sbjct: 1842 TQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVEETL 1901
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV-TKAIDK 1015
+++ +L + E E+++ LK R L K K+ K REK+ E + I K
Sbjct: 1902 KLERDQLKESLQETKARDLEIQQELKTAR-MLSKE-HKETVDKLREKISEKTIQISDIQK 1959
Query: 1016 DIREYAVALDKCLMEFHREKME 1037
D+ + L K + E +++++
Sbjct: 1960 DLDKSKDELQKKIQELQKKELQ 1981
Score = 55.6 bits (128), Expect = 1e-06
Identities = 81/445 (18%), Positives = 200/445 (44%), Gaps = 43/445 (9%)
Query: 604 NVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNE 663
++P ++E++ +++Q K +E+ + S +K+ + E+ E R+ + +I +
Sbjct: 751 SLPSEVERLRKEIQD---KSEELHIITSEKDKLFS----EVVHKESRVQGLLEEIGKTKD 803
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPML--------DRYIQEIKTVTKKFEAVKEQCGD 715
+ + +Q+ K +H D +R QEI ++K+ + G
Sbjct: 804 DLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGA 863
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
+ +E L T + + +++ N ++ +++L + LQT+ +KT E+L T
Sbjct: 864 LKTE--LSYKTQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKTLITEKLQQTL 921
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
++V+ + ++ KQLQ + + +E++ E ++++++ I
Sbjct: 922 EEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETIN 981
Query: 836 AGSAYIAKVEVAFN-----KVKSLDAEIQQ-----HKKKNVPREMEKIQEA---NDKLME 882
+ I++ EV+ N E QQ KK+++ + + A +++++E
Sbjct: 982 TLKSKISE-EVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIE 1040
Query: 883 KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL 942
+Q++I + Q + L+ IA++E K DL +N+ + I N Q++ L ++L
Sbjct: 1041 QQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENI-----EMTIEN-QEELRLLGDEL 1094
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK--DIEKKF 1000
+ EK I K+ +L + L+E+++ LK +L++ + +++++
Sbjct: 1095 KKQQEIVAQEKNHAIKKEGEL----SRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEM 1150
Query: 1001 REKMYELHVTKAIDKDIREYAVALD 1025
E +++ + + +++ + L+
Sbjct: 1151 SEMQKKINEIENLKNELKNKELTLE 1175
Score = 54.0 bits (124), Expect = 3e-06
Identities = 164/840 (19%), Positives = 335/840 (39%), Gaps = 68/840 (8%)
Query: 186 KYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
KY L+ +++ ++ K + + +++ A + EL SYK K E ++
Sbjct: 832 KYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTEL--SYKTQELQEKTREV---QERL 886
Query: 246 NEIEYNKFILLESQNQEKIDKRNEQIVETAKIAE-IENI-TEVQTNEEAENATKTILEKV 303
NE+E K LE+++ E+ + T K+ + +E + T Q ++ + +++ +
Sbjct: 887 NEMEQLKE-QLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIER 945
Query: 304 ESLKSD-HKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITS 362
+ LKSD H D +E+ E H + +
Sbjct: 946 DQLKSDIHDTVNMNIDTQEQLRNAL--ESLKQHQETINTLKSKISEEVSRNLHMEENTGE 1003
Query: 363 ANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKIT 422
+ Q L + EI E ++ + QE +EL Q +
Sbjct: 1004 TKDEFQQKMVGIDKKQDLEAKNTQT---LTADVKDNEIIEQQRKIFSLIQEKNELQQMLE 1060
Query: 423 KLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEV 482
+ + EKE ++ +L KE + ++N+ + + LLG+ +K + + +
Sbjct: 1061 SV------IAEKEQLKTDL--KENIEMTIENQEE---LRLLGDELKKQQEIVAQEKNHAI 1109
Query: 483 RNEVXXXXXXXXXXXXXXXXLEAERKHIRE------SLNERRSELTKAEDKIYKACG-TQ 535
+ E L+ + + ++E ++ E SE+ K ++I +
Sbjct: 1110 KKE-GELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELK 1168
Query: 536 PYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCN----RGFENESEX 591
++TL T +L + N + I K + LK+ RG+ E E
Sbjct: 1169 NKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEA 1228
Query: 592 XXXXXXXXXXXMNVPGKLEKVT-EDLQRA-SAKKDEILSMKSLNEKITTLKDTEIPQLEK 649
++ K + T ++L+R+ S K +I++ + L + T L++ EIP L +
Sbjct: 1229 TGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQE-EIPVLHE 1287
Query: 650 RIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAV 709
++ +K ++ET E TM+ +E + +T K D L R E + +KF+
Sbjct: 1288 E-QELLPNVKKVSETQE--TMNELELLTEQSTTK----DSTTLARIEMERLRLNEKFQES 1340
Query: 710 KEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE 769
+E+ + E ++ T K+ + K L+ ++ T K+ ++ Q+ E+ KE
Sbjct: 1341 QEEIKSLTKERD-NLKTIKEA-LEVKHDQLKEHIRETLAKI----QESQSKQEQSLNMKE 1394
Query: 770 ELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR 829
+ T K V ++ + L + ++ KEK + ++R
Sbjct: 1395 KDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEK-----DDLQR 1449
Query: 830 NRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK-IQEANDKLMEKQKQIM 888
++++++ S + K + K L+ E + +E E+ I E L EK+ +I
Sbjct: 1450 LQEVLQSESDQL-KENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEIS 1508
Query: 889 TDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE 948
T ++ L D L+++I QE+Y+++ N+ + N KQ E +
Sbjct: 1509 TIQKQLEAINDKLQNKI--QEIYEKEEQLNIKQISEVQENVNELKQFKEHRK----AKDS 1562
Query: 949 ELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN--ELEKSLSKDIEKKFREKMYE 1006
L ES +++ T Q+ E + + K+ +K + ++E+ K+ K+ KM E
Sbjct: 1563 ALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKE 1622
Score = 49.2 bits (112), Expect = 9e-05
Identities = 90/517 (17%), Positives = 202/517 (39%), Gaps = 30/517 (5%)
Query: 506 ERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFII 565
E + ++E L R S L E + K T+ TL + T ++ D + + +S
Sbjct: 888 EMEQLKEQLENRDSPLQTVERE--KTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIER 945
Query: 566 NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDE 625
++ K + D N + + + + K++E++ R ++
Sbjct: 946 DQLKSDIHDT-----VNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEEN 1000
Query: 626 ILSMKS-LNEKITTL-KDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK 683
K +K+ + K ++ + + D + + E +I + E + +
Sbjct: 1001 TGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLE 1060
Query: 684 QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK--ISTLRN 741
+ + L ++E +T + + GD + VA K K++ +S +
Sbjct: 1061 SVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCD 1120
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXX 801
R+ ++KL +++LQ ++ +EE+ QKK+ +I NL+ K +
Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKE-------LT 1173
Query: 802 XXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
L L E E + + + L E ++ + + ++ ++A Q
Sbjct: 1174 LEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQT 1233
Query: 862 KKK------NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
K++ ++ E I E + EK QI+ + Q L K L++EI +++L
Sbjct: 1234 KEELKIAHIHLKEHQETIDELRRSVSEKTAQII-NTQDLEKSHTKLQEEIPVLH-EEQEL 1291
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
N+ K ++ + + L E+ + L E ++ + FQ+ E +L+
Sbjct: 1292 LPNV---KKVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLT 1348
Query: 976 ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKA 1012
+ + +LK + LE +++ RE + ++ +++
Sbjct: 1349 KERDNLKTIKEALEVK-HDQLKEHIRETLAKIQESQS 1384
Score = 42.3 bits (95), Expect = 0.010
Identities = 39/190 (20%), Positives = 90/190 (47%), Gaps = 10/190 (5%)
Query: 736 ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKA----KEELLNTQKKVQDIVNLEESK--K 789
I+ L+ +V + K L + +Q L +K KEE+ + + K+ I +LE+ K K
Sbjct: 2380 IAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKI-DLEKMKNAK 2438
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAK-TEVVRRNRDLIEAGSAYIAKVEVAF 848
+ + + I L L+ +A+ T V+ + D +
Sbjct: 2439 EFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGI 2498
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
V++ A I + + + +E+ K+++ N++L++++ +++++ Q L+ ++ T K+ K+
Sbjct: 2499 --VQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKR 2556
Query: 909 EVYKRDLDDN 918
E +K+ +N
Sbjct: 2557 EAHKQVTCEN 2566
Score = 39.5 bits (88), Expect = 0.071
Identities = 74/398 (18%), Positives = 164/398 (41%), Gaps = 24/398 (6%)
Query: 650 RIVDVDTQIKTLNETVEEITMSLIEPEQKMTT-AKQIHGDMPMLDRYIQEIKTVTKKFEA 708
RI+ T + + +ET+ + + K T ++ D +L RY +EI + K+ E
Sbjct: 303 RIICTITPV-SFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEE 361
Query: 709 VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAK 768
V + E ++ D QK+ +++ + L + L E K K K
Sbjct: 362 VSLETRAQAMEKDQLAQLLEEKDLLQKVQN--EKIENLTRML-VTSSSLTLQQELKAKRK 418
Query: 769 EELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+ K+ + N + Q + ++ ++ + + + +
Sbjct: 419 RRVTWCLGKINKMKNSNYAD-QFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLD 477
Query: 829 RNRDLIEAGSAYIAKVEVAFNKVKSLDAE-----IQQHKKKNVPREME-KIQEAND--KL 880
++ + + E +++ SL A+ + + + EME K++E ND +
Sbjct: 478 TLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEF 537
Query: 881 MEKQKQIMTDRQV-LTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN 939
+++ D+++ L +I LK+ + +EVY +DL++ L + + ++++D++
Sbjct: 538 EALERKTKKDQEMQLIHEISNLKNLVKHREVYNQDLENEL-----SSKVELLREKEDQIK 592
Query: 940 EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ I+ ++L + + + + + L + + + E S+++E K
Sbjct: 593 KLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELK 652
Query: 1000 FREKMYELHVT-KAIDKDIREYAVALD-KCLMEFHREK 1035
EKM EL T K ++ DI+ Y L+ K M+ EK
Sbjct: 653 --EKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEK 688
Score = 38.3 bits (85), Expect = 0.16
Identities = 143/833 (17%), Positives = 325/833 (39%), Gaps = 78/833 (9%)
Query: 191 LDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTS--FNKEEE-KIAN---EKS 244
L+ ++ + K+ +L+ +E T+K ++ +L+++ ++ + K+EE KI + ++
Sbjct: 1678 LEEMRSVTKE-RDDLRSVEE---TLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEH 1733
Query: 245 SNEIEYNKFILLESQN-----QEKIDKRNEQI-VETAKIAEIENITEVQTNEEAENATKT 298
I+ + I+ E N Q+ ++ N+ + + KI E I + E+ E K
Sbjct: 1734 QETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDK- 1792
Query: 299 ILEKVESLKSDHKVQKSQADEEEKKA--QGFVDECRSGHTQXXXXXXXXXXXXXXXXXXX 356
L + S K+D K+ Q D E A Q + E ++ Q
Sbjct: 1793 -LRGIVSEKTD-KLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEME 1850
Query: 357 XXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDE 416
+QS H+ E ++ +E + + E + E D+
Sbjct: 1851 QLKKQIKDQSLTLSKLEIENLNLAQELHENLEE---MKSVMKERDNLRRVEETLKLERDQ 1907
Query: 417 LSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVT-I 475
L + + Q K ++ E I++ LKT +L +HK + +L + EK ++ I
Sbjct: 1908 LKESL-----QETKARDLE-IQQELKTAR----MLSKEHKETVDKLREKISEKTIQISDI 1957
Query: 476 NKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ 535
K + ++E+ ++ + + +NE + E C
Sbjct: 1958 QKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEPNYLCKCEMD 2017
Query: 536 PYDVTLSKYTTTVE-----KLQDEQNVLQSSMFII-NKYKGQLKDNSCCPLCNRGFENES 589
+ +T + + E K +DE ++ S+ + +++ L++ N + E
Sbjct: 2018 NFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEK 2077
Query: 590 EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEK 649
+ K ++ E L+R S D + L+ + K+ E ++ K
Sbjct: 2078 RLLSDGQQHLMESLRE--KCSRIKELLKRYSEMDDHYECLNRLSLDLE--KEIEFHRIMK 2133
Query: 650 R---IVDVDTQIKT-LNETVEEITMSLIEPEQK----MTTAKQIHGDMPMLDRYIQEIKT 701
+ ++ T+IK +E + + M I+ +K + + + D + R ++++K
Sbjct: 2134 KLKYVLSYVTKIKEEQHECINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKL 2193
Query: 702 VTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN--KKLQT 759
++E D + T +F+Q +S + + ++ LN +KL+
Sbjct: 2194 NQNMDLHIEEILKDFSESEFPSIKT----EFQQVLSNRKEMTQFLEEWLNTRFDIEKLKN 2249
Query: 760 LYEKKTKAKEELLNT-QKKVQDIVN----LEESKKQLQSDCXXXXXXXXXXXXAITPLEV 814
+K+ ++ N ++ I+N EE + + +
Sbjct: 2250 GIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQ 2309
Query: 815 ALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ------HKKKNVPR 868
LK + + +V +D A ++ K++ L+ + + HK+ + +
Sbjct: 2310 TLKTSLASGAQVNPTTQDNKNPHVTSRA-TQLTTEKIRELENSLHEAKESAMHKESKIIK 2368
Query: 869 EMEKIQEANDKLMEKQKQIMTDRQVLTK---KIDTLKDEIA-KQEVYKRDLDDNLCLRKA 924
++++ ND + + Q ++ + L K I L+D++A + YK +++D L ++
Sbjct: 2369 MQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIED-LKMKLV 2427
Query: 925 QTDITNWQKQDDELNEKLNGINKEELNEKESL-IIKQTKLFQQKAECTGALSE 976
+ D+ K E ++++ +KE + ++++ Q+A+ T +SE
Sbjct: 2428 KIDLEK-MKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISE 2479
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 81.0 bits (191), Expect = 2e-14
Identities = 196/1001 (19%), Positives = 419/1001 (41%), Gaps = 96/1001 (9%)
Query: 54 TGQMPPGSRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK--VTALAKKKTK 111
T + P S E V D ++ E L Q + N + E +S K T L +K
Sbjct: 259 TKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEA 318
Query: 112 FQT-LDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDE 170
Q LD L ++ K KD+ A+ L+ +L +K ++ + ++D + E
Sbjct: 319 LQEQLDERLQELE---KIKDL--HMAEKTKLI-TQLRDAKNLIEQL----EQDKGMVIAE 368
Query: 171 GKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K+ E+ + ++ + R+K++ Q +L E + +A +ELE +
Sbjct: 369 TKRQMHETLEMKE-EEIAQLRSRIKQMT---TQGEELREQKEKSERAAFEELEKALSTAQ 424
Query: 231 SFNKEEEKIANEKSSNEIEYNKFILLESQN-QEKIDKRNEQIVETAKIAEIENITEVQTN 289
+ K+ E K E + Q+++ + +++V+ K + E I ++Q
Sbjct: 425 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 484
Query: 290 EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXX 349
E E A K + L + ++ + E+ K A +++ +S + +
Sbjct: 485 HEKELARKE-----QELTKKLQTREREFQEQMKVA---LEKSQSEYLKISQEKEQQESLA 536
Query: 350 XXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQ 409
I + +++ ++ E +++E + N+ +
Sbjct: 537 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK---NQSKDLAVH 593
Query: 410 YEQEMDELSQKITKL-QKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPE 468
E E ++ +++IT + +K +L+ + ++ L T++ Q VLK +++T + +L +
Sbjct: 594 LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ--VLKQQYQTEMEKLREKCEQ 651
Query: 469 KDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI 528
+ + +K E+ L+ ++ + ESL+ SE+ KA K+
Sbjct: 652 EKETLLKDK-------EIIFQAHIEEMNEKTLEKLDVKQTEL-ESLSSELSEVLKARHKL 703
Query: 529 YKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM-FIINKYKGQLK--DNSCCPLCNRGF 585
+ D T K+ +++N Q + II +++ ++ + + N+
Sbjct: 704 EEELSVLK-DQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 762
Query: 586 ENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIP 645
E N+ +++ +LQ+ASAK D S +S + T + ++
Sbjct: 763 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 822
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDR----YIQEIK 700
QL+++++D++T+ L + V E+ + ++ K Q+ M L++ Q++K
Sbjct: 823 QLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK 882
Query: 701 TVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL 760
++T+ +E+ K + G+ + E T + K+ Q + ++ +KL+A + L
Sbjct: 883 SLTQVYES-KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHIL 941
Query: 761 YEK-KTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEK 819
E+ +TK K + +K Q ++E+ K+ D T LE++ KEK
Sbjct: 942 NEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLD----QEAKLKKELENTALELSQKEK 997
Query: 820 IEAKTEVVRRNRDLIEAGSAYI--AKVEVAFNKVKSLDAEIQQHKK----------KNVP 867
+ + ++ +A SA I A + N+ + +++ + H++ K +
Sbjct: 998 -----QFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLN 1052
Query: 868 REMEKIQEAND-KLMEKQKQIM----------TDRQVLTKKIDTLKDEIAKQEVYKRDLD 916
++ E++QE ++ +L EK++++ +++ + K+I LK+E KQ+ +L
Sbjct: 1053 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQ 1112
Query: 917 DNLCLRKAQT-----DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECT 971
+ L + A D T + ++L LN KE +E L+ + + K + +
Sbjct: 1113 EQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVS 1172
Query: 972 GALSELK------KSLKGFRNELEKSL-SKDIE-KKFREKM 1004
S+LK +SLK + KSL K +E KK E++
Sbjct: 1173 ELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1213
Score = 75.4 bits (177), Expect = 1e-12
Identities = 108/460 (23%), Positives = 209/460 (45%), Gaps = 37/460 (8%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTE--IPQLE--KRIVDVDTQIK---TLN 662
E++ E LQ KD L M + IT L+D + I QLE K +V +T+ + TL
Sbjct: 321 EQLDERLQELEKIKD--LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-----IKTVTKKFEAVKEQCGDVD 717
EEI +Q T +++ +R E + T K EA ++ ++D
Sbjct: 379 MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMD 438
Query: 718 SEMTLDVATAKQ--VDFKQKISTLRNRVKTTQKKLNAHN-KKLQTLYEKKTKAKEELLNT 774
++ T+++ + +Q++S ++ V KK + KLQ L+EK+ KE+ L
Sbjct: 439 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTK 498
Query: 775 QKKVQDIVNLEESKKQLQ-SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
+ + ++ E+ K L+ S LE +K TE + RDL
Sbjct: 499 KLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDL 558
Query: 834 IEAGSAYIAKV-EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
+ Y ++ E+ + KSL Q K V E EK + N ++ ++ T+ +
Sbjct: 559 QQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEK-NKHNKEITVMVEKHKTELE 617
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK--LNGINKEEL 950
L + D L E K +V K+ + + + + Q+++ L +K + + EE+
Sbjct: 618 SLKHQQDALWTE--KLQVLKQQYQTEMEKLREKCE----QEKETLLKDKEIIFQAHIEEM 671
Query: 951 NEK--ESLIIKQTKLFQQKAECTGALS---ELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
NEK E L +KQT+L +E + L +L++ L +++ +K + +++E K E+
Sbjct: 672 NEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDK-MKQELEAKMDEQ-- 728
Query: 1006 ELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
+ H + +D I+E+ V++ + ++++ + ++++E
Sbjct: 729 KNHHQQQVDSIIKEHEVSIQRTEKAL-KDQINQLELLLKE 767
Score = 56.8 bits (131), Expect = 4e-07
Identities = 128/712 (17%), Positives = 286/712 (40%), Gaps = 76/712 (10%)
Query: 386 QAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTK 444
QA E E+ ++++ + +E E+ E+ + KL+++ + LK++ + +++ L+ K
Sbjct: 665 QAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAK 724
Query: 445 EKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLE 504
+ KN H+ + ++ K+ V+I + E +++++ +
Sbjct: 725 MDE---QKNHHQQQVDSII-----KEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQ 776
Query: 505 AERKHIRESLNERRSELTKAEDK--IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
A +++ + EL +A K ++++ + ++ T Y + +LQ + L++
Sbjct: 777 AHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQT-KAYEEQLAQLQQKLLDLETER 835
Query: 563 FIINKYKGQL---KDNSCCPLCNRGF-------ENESEXXXXXXXXXXXXMNVPGKLEKV 612
++ K ++ K + C L + E + KLE
Sbjct: 836 ILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDG 895
Query: 613 TEDLQRAS----AKKDEILSMKSLNEKITTLKDTEIPQLEKRI----VDVDTQIKTLNET 664
++ ++ K++ IL M+ +K + ++ E I + +T+ K +
Sbjct: 896 NKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 955
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ----EIKTVTKKFEAVKEQCGDVDSEM 720
+E++ E ++ T K++ L + ++ E+ K+F A + +S
Sbjct: 956 MEKVKQKAKEMQE--TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAG 1013
Query: 721 TLDVATAKQVDFKQKIST--------LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D + + + K++I + L + + +KKLN ++LQ ++E + + KE+ +
Sbjct: 1014 ISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEV 1073
Query: 773 NTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
K Q I+ K+++ + + L+ LK+K + +
Sbjct: 1074 AELK--QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK 1131
Query: 833 LIEAGSAYIAKVEVAFNKVKSLDAEIQQ---HKKKNVPREMEKIQEANDKLMEKQKQIMT 889
L A++ K+EV NK + +Q+ K + K+ E KL ++ +
Sbjct: 1132 L----KAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN---EKLNGI- 945
+ K +L+D+ + + +L L + +T+ K ++ +N K N I
Sbjct: 1188 LKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAIL 1247
Query: 946 ------NKEELNEKESLIIKQ---TKLFQQKAECTGALSELKKSLKGFRNELE------K 990
KE+L+IK ++L Q + T + L S + ++LE K
Sbjct: 1248 SRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIK 1307
Query: 991 SLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMI 1042
S+ DIE EK + + ++ A + C+ + +E ENIN +
Sbjct: 1308 SMKADIESLVTEK----EALQKEGGNQQQAASEKESCITQLKKELSENINAV 1355
Score = 55.2 bits (127), Expect = 1e-06
Identities = 167/831 (20%), Positives = 338/831 (40%), Gaps = 98/831 (11%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQN---QEKIDKRNEQI 271
++ + E+E K T E K+ E + E E K IL+E +N Q + ++ E
Sbjct: 870 LEKQNSEMEQKVKSLTQVY--ESKL--EDGNKEQEQTKQILVEKENMILQMREGQKKEIE 925
Query: 272 VETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDEC 331
+ T K++ E+ + NEE E K +K+E +K QK++ +E K + E
Sbjct: 926 ILTQKLSAKEDSIHI-LNEEYETKFKNQEKKMEKVK-----QKAKEMQETLKKKLLDQEA 979
Query: 332 RSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENEL 391
+ + ++ AN + ++ E+
Sbjct: 980 KL--KKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQI--ESLTEV 1035
Query: 392 NIEECQQEINEDEKAVEQYEQEMDELSQ-KITKLQKQTAKLKEKEMIEENLKTKEKQLIV 450
+ E I+ EK + Q +E+ E+ + ++ + +++ A+LK+K ++ +++++
Sbjct: 1036 HRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILL---FGCEKEEM-- 1090
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
NK T L E ++D T+N E++ ++ L+A + +
Sbjct: 1091 --NKEITWLKE---EGVKQD--TTLN----ELQEQLKQKSAHVNSLAQDETKLKAHLEKL 1139
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVT-LSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
LN+ E T ++++ + D +S+ T+ ++ +E L+SS NK
Sbjct: 1140 EVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK-- 1197
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR-ASAKKDEILS 628
L+D S F+ SE LE T +L +S+K + ILS
Sbjct: 1198 -SLEDKSL------EFKKLSEELAIQLDICCK--KTEALLEAKTNELINISSSKTNAILS 1248
Query: 629 MKSLNEKITT-------LKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT 681
S + TT +K + +LE ++ + + TLN + ++ T L E+K
Sbjct: 1249 RISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQL---EEKENQ 1305
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRN 741
K + D+ L VT+K EA++++ G+ + + Q+ K+++S N
Sbjct: 1306 IKSMKADIESL---------VTEK-EALQKEGGNQQQAASEKESCITQL--KKELSENIN 1353
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXX 801
V +++L ++ +L ++ T +L N+ + + +KQ +
Sbjct: 1354 AVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQ 1413
Query: 802 XXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
+ L KEKI A +V + E ++ N VK L +++
Sbjct: 1414 VQDLSFKVDTLS---KEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELK 1470
Query: 862 KKKNVPRE------MEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
K+ ++ E++ + N + + ++ D+ + KK L+ E+ Q +L
Sbjct: 1471 SKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMEL 1530
Query: 916 DDNLCLRKAQTD-----ITNWQKQDD----ELNEKL---NGINKEELNE----KESLIIK 959
+D++ + + + + N+ +Q D EL +KL + +E+ N +E ++
Sbjct: 1531 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1590
Query: 960 QTKLFQQKAECTGALSELKK---SLKGFRNELEKSLSKDIEKKFREKMYEL 1007
+ +++ KAE EL+ S+K EL K+L +E + K+ EL
Sbjct: 1591 ENQVYSMKAELETKKKELEHVNLSVKSKEEEL-KALEDRLESESAAKLAEL 1640
Score = 51.6 bits (118), Expect = 2e-05
Identities = 126/647 (19%), Positives = 254/647 (39%), Gaps = 56/647 (8%)
Query: 386 QAENELNIEECQQEINE-----DEKAVEQYEQEMDELSQKITKLQKQT-AKLKEKEMIEE 439
Q +N +++ E + I+ DE+ E +Q D LS K+ L K+ + L++ +
Sbjct: 1382 QLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQD-LSFKVDTLSKEKISALEQVDDWSN 1440
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVP-------EKDFAVTINKFECEVRNEVXXXXXX 492
+K+ +H+ + EL + EKD + + K E + +N+
Sbjct: 1441 KFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNK--RFDCL 1498
Query: 493 XXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI-YKACGTQPYDVTLSKYTTTVEKL 551
+E + ++ L + + + + ED I K + + L Y +
Sbjct: 1499 KGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE 1558
Query: 552 QDEQ-NVLQSSMFIINKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
E LQ + + ++K+ L N+ + ++E ++V K
Sbjct: 1559 HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSK 1618
Query: 609 LE--KVTED-LQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVD----VDTQIKTL 661
E K ED L+ SA K L K+ +KI +K + Q+E++ ++ + L
Sbjct: 1619 EEELKALEDRLESESAAKLAELKRKA-EQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEL 1677
Query: 662 NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT 721
N ++E + E+K+ + + + ++ R + + T++ EA + C E
Sbjct: 1678 NTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEK 1737
Query: 722 LDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
+ V + K+K L RV +++ + + +++ Y+++ E Q + Q +
Sbjct: 1738 ISVLQRNLTE-KEK---LLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSM 1793
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
+ LQ + E K I+AK + D+ +
Sbjct: 1794 IG------HLQEELEEKNKKYSLIVAQHVEKEGG-KNNIQAKQNLENVFDDVQKTLQEKE 1846
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPR-EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
++ K+K LD+ + ++K V R EME++ +KL Q+ M R T+ ++
Sbjct: 1847 LTCQILEQKIKELDSCLV--RQKEVHRVEMEELTSKYEKLQALQQ--MDGRNKPTELLEE 1902
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+E +K + + L ++N + Q ++L KL G +E+ + ++ Q
Sbjct: 1903 NTEEKSKSHLVQPKL------------LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQ 1950
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYEL 1007
L + E L LKK R E K +D+E K + +L
Sbjct: 1951 KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 1997
Score = 35.1 bits (77), Expect = 1.5
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 7/155 (4%)
Query: 161 QEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQ 219
Q+D E ++ E + +D ++ + + + LK L+ + T + K+
Sbjct: 1950 QKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKE 2009
Query: 220 KELEDSYKKNTSFNKEEEKIANEKSSNEIEYN---KFILLESQNQEKIDKRNEQIVETAK 276
+ELE + K+ + NK +E A S++ E N K I + + ++ KR E+I++ +
Sbjct: 2010 QELEMTIKE--TINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE 2067
Query: 277 IAEIENITEVQTN-EEAENATKTILEKVESLKSDH 310
+ ++QT EE + + LE+ E+ +D+
Sbjct: 2068 EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDN 2102
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 81.0 bits (191), Expect = 2e-14
Identities = 196/1001 (19%), Positives = 419/1001 (41%), Gaps = 96/1001 (9%)
Query: 54 TGQMPPGSRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK--VTALAKKKTK 111
T + P S E V D ++ E L Q + N + E +S K T L +K
Sbjct: 259 TKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEA 318
Query: 112 FQT-LDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDE 170
Q LD L ++ K KD+ A+ L+ +L +K ++ + ++D + E
Sbjct: 319 LQEQLDERLQELE---KIKDL--HMAEKTKLI-TQLRDAKNLIEQL----EQDKGMVIAE 368
Query: 171 GKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K+ E+ + ++ + R+K++ Q +L E + +A +ELE +
Sbjct: 369 TKRQMHETLEMKE-EEIAQLRSRIKQMT---TQGEELREQKEKSERAAFEELEKALSTAQ 424
Query: 231 SFNKEEEKIANEKSSNEIEYNKFILLESQN-QEKIDKRNEQIVETAKIAEIENITEVQTN 289
+ K+ E K E + Q+++ + +++V+ K + E I ++Q
Sbjct: 425 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 484
Query: 290 EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXX 349
E E A K + L + ++ + E+ K A +++ +S + +
Sbjct: 485 HEKELARKE-----QELTKKLQTREREFQEQMKVA---LEKSQSEYLKISQEKEQQESLA 536
Query: 350 XXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQ 409
I + +++ ++ E +++E + N+ +
Sbjct: 537 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK---NQSKDLAVH 593
Query: 410 YEQEMDELSQKITKL-QKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPE 468
E E ++ +++IT + +K +L+ + ++ L T++ Q VLK +++T + +L +
Sbjct: 594 LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ--VLKQQYQTEMEKLREKCEQ 651
Query: 469 KDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI 528
+ + +K E+ L+ ++ + ESL+ SE+ KA K+
Sbjct: 652 EKETLLKDK-------EIIFQAHIEEMNEKTLEKLDVKQTEL-ESLSSELSEVLKARHKL 703
Query: 529 YKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM-FIINKYKGQLK--DNSCCPLCNRGF 585
+ D T K+ +++N Q + II +++ ++ + + N+
Sbjct: 704 EEELSVLK-DQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 762
Query: 586 ENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIP 645
E N+ +++ +LQ+ASAK D S +S + T + ++
Sbjct: 763 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 822
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDR----YIQEIK 700
QL+++++D++T+ L + V E+ + ++ K Q+ M L++ Q++K
Sbjct: 823 QLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK 882
Query: 701 TVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL 760
++T+ +E+ K + G+ + E T + K+ Q + ++ +KL+A + L
Sbjct: 883 SLTQVYES-KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHIL 941
Query: 761 YEK-KTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEK 819
E+ +TK K + +K Q ++E+ K+ D T LE++ KEK
Sbjct: 942 NEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLD----QEAKLKKELENTALELSQKEK 997
Query: 820 IEAKTEVVRRNRDLIEAGSAYI--AKVEVAFNKVKSLDAEIQQHKK----------KNVP 867
+ + ++ +A SA I A + N+ + +++ + H++ K +
Sbjct: 998 -----QFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLN 1052
Query: 868 REMEKIQEAND-KLMEKQKQIM----------TDRQVLTKKIDTLKDEIAKQEVYKRDLD 916
++ E++QE ++ +L EK++++ +++ + K+I LK+E KQ+ +L
Sbjct: 1053 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQ 1112
Query: 917 DNLCLRKAQT-----DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECT 971
+ L + A D T + ++L LN KE +E L+ + + K + +
Sbjct: 1113 EQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVS 1172
Query: 972 GALSELK------KSLKGFRNELEKSL-SKDIE-KKFREKM 1004
S+LK +SLK + KSL K +E KK E++
Sbjct: 1173 ELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1213
Score = 75.4 bits (177), Expect = 1e-12
Identities = 108/460 (23%), Positives = 209/460 (45%), Gaps = 37/460 (8%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTE--IPQLE--KRIVDVDTQIK---TLN 662
E++ E LQ KD L M + IT L+D + I QLE K +V +T+ + TL
Sbjct: 321 EQLDERLQELEKIKD--LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-----IKTVTKKFEAVKEQCGDVD 717
EEI +Q T +++ +R E + T K EA ++ ++D
Sbjct: 379 MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMD 438
Query: 718 SEMTLDVATAKQ--VDFKQKISTLRNRVKTTQKKLNAHN-KKLQTLYEKKTKAKEELLNT 774
++ T+++ + +Q++S ++ V KK + KLQ L+EK+ KE+ L
Sbjct: 439 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTK 498
Query: 775 QKKVQDIVNLEESKKQLQ-SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
+ + ++ E+ K L+ S LE +K TE + RDL
Sbjct: 499 KLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDL 558
Query: 834 IEAGSAYIAKV-EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
+ Y ++ E+ + KSL Q K V E EK + N ++ ++ T+ +
Sbjct: 559 QQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEK-NKHNKEITVMVEKHKTELE 617
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK--LNGINKEEL 950
L + D L E K +V K+ + + + + Q+++ L +K + + EE+
Sbjct: 618 SLKHQQDALWTE--KLQVLKQQYQTEMEKLREKCE----QEKETLLKDKEIIFQAHIEEM 671
Query: 951 NEK--ESLIIKQTKLFQQKAECTGALS---ELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
NEK E L +KQT+L +E + L +L++ L +++ +K + +++E K E+
Sbjct: 672 NEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDK-MKQELEAKMDEQ-- 728
Query: 1006 ELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
+ H + +D I+E+ V++ + ++++ + ++++E
Sbjct: 729 KNHHQQQVDSIIKEHEVSIQRTEKAL-KDQINQLELLLKE 767
Score = 56.8 bits (131), Expect = 4e-07
Identities = 128/712 (17%), Positives = 286/712 (40%), Gaps = 76/712 (10%)
Query: 386 QAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTK 444
QA E E+ ++++ + +E E+ E+ + KL+++ + LK++ + +++ L+ K
Sbjct: 665 QAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAK 724
Query: 445 EKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLE 504
+ KN H+ + ++ K+ V+I + E +++++ +
Sbjct: 725 MDE---QKNHHQQQVDSII-----KEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQ 776
Query: 505 AERKHIRESLNERRSELTKAEDK--IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
A +++ + EL +A K ++++ + ++ T Y + +LQ + L++
Sbjct: 777 AHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQT-KAYEEQLAQLQQKLLDLETER 835
Query: 563 FIINKYKGQL---KDNSCCPLCNRGF-------ENESEXXXXXXXXXXXXMNVPGKLEKV 612
++ K ++ K + C L + E + KLE
Sbjct: 836 ILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDG 895
Query: 613 TEDLQRAS----AKKDEILSMKSLNEKITTLKDTEIPQLEKRI----VDVDTQIKTLNET 664
++ ++ K++ IL M+ +K + ++ E I + +T+ K +
Sbjct: 896 NKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 955
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ----EIKTVTKKFEAVKEQCGDVDSEM 720
+E++ E ++ T K++ L + ++ E+ K+F A + +S
Sbjct: 956 MEKVKQKAKEMQE--TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAG 1013
Query: 721 TLDVATAKQVDFKQKIST--------LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D + + + K++I + L + + +KKLN ++LQ ++E + + KE+ +
Sbjct: 1014 ISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEV 1073
Query: 773 NTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
K Q I+ K+++ + + L+ LK+K + +
Sbjct: 1074 AELK--QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK 1131
Query: 833 LIEAGSAYIAKVEVAFNKVKSLDAEIQQ---HKKKNVPREMEKIQEANDKLMEKQKQIMT 889
L A++ K+EV NK + +Q+ K + K+ E KL ++ +
Sbjct: 1132 L----KAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1187
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN---EKLNGI- 945
+ K +L+D+ + + +L L + +T+ K ++ +N K N I
Sbjct: 1188 LKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAIL 1247
Query: 946 ------NKEELNEKESLIIKQ---TKLFQQKAECTGALSELKKSLKGFRNELE------K 990
KE+L+IK ++L Q + T + L S + ++LE K
Sbjct: 1248 SRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIK 1307
Query: 991 SLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMI 1042
S+ DIE EK + + ++ A + C+ + +E ENIN +
Sbjct: 1308 SMKADIESLVTEK----EALQKEGGNQQQAASEKESCITQLKKELSENINAV 1355
Score = 55.2 bits (127), Expect = 1e-06
Identities = 167/831 (20%), Positives = 338/831 (40%), Gaps = 98/831 (11%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQN---QEKIDKRNEQI 271
++ + E+E K T E K+ E + E E K IL+E +N Q + ++ E
Sbjct: 870 LEKQNSEMEQKVKSLTQVY--ESKL--EDGNKEQEQTKQILVEKENMILQMREGQKKEIE 925
Query: 272 VETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDEC 331
+ T K++ E+ + NEE E K +K+E +K QK++ +E K + E
Sbjct: 926 ILTQKLSAKEDSIHI-LNEEYETKFKNQEKKMEKVK-----QKAKEMQETLKKKLLDQEA 979
Query: 332 RSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENEL 391
+ + ++ AN + ++ E+
Sbjct: 980 KL--KKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQI--ESLTEV 1035
Query: 392 NIEECQQEINEDEKAVEQYEQEMDELSQ-KITKLQKQTAKLKEKEMIEENLKTKEKQLIV 450
+ E I+ EK + Q +E+ E+ + ++ + +++ A+LK+K ++ +++++
Sbjct: 1036 HRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILL---FGCEKEEM-- 1090
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
NK T L E ++D T+N E++ ++ L+A + +
Sbjct: 1091 --NKEITWLKE---EGVKQD--TTLN----ELQEQLKQKSAHVNSLAQDETKLKAHLEKL 1139
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVT-LSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
LN+ E T ++++ + D +S+ T+ ++ +E L+SS NK
Sbjct: 1140 EVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK-- 1197
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR-ASAKKDEILS 628
L+D S F+ SE LE T +L +S+K + ILS
Sbjct: 1198 -SLEDKSL------EFKKLSEELAIQLDICCK--KTEALLEAKTNELINISSSKTNAILS 1248
Query: 629 MKSLNEKITT-------LKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT 681
S + TT +K + +LE ++ + + TLN + ++ T L E+K
Sbjct: 1249 RISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQL---EEKENQ 1305
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRN 741
K + D+ L VT+K EA++++ G+ + + Q+ K+++S N
Sbjct: 1306 IKSMKADIESL---------VTEK-EALQKEGGNQQQAASEKESCITQL--KKELSENIN 1353
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXX 801
V +++L ++ +L ++ T +L N+ + + +KQ +
Sbjct: 1354 AVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQ 1413
Query: 802 XXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
+ L KEKI A +V + E ++ N VK L +++
Sbjct: 1414 VQDLSFKVDTLS---KEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELK 1470
Query: 862 KKKNVPRE------MEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
K+ ++ E++ + N + + ++ D+ + KK L+ E+ Q +L
Sbjct: 1471 SKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMEL 1530
Query: 916 DDNLCLRKAQTD-----ITNWQKQDD----ELNEKL---NGINKEELNE----KESLIIK 959
+D++ + + + + N+ +Q D EL +KL + +E+ N +E ++
Sbjct: 1531 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1590
Query: 960 QTKLFQQKAECTGALSELKK---SLKGFRNELEKSLSKDIEKKFREKMYEL 1007
+ +++ KAE EL+ S+K EL K+L +E + K+ EL
Sbjct: 1591 ENQVYSMKAELETKKKELEHVNLSVKSKEEEL-KALEDRLESESAAKLAEL 1640
Score = 51.6 bits (118), Expect = 2e-05
Identities = 126/647 (19%), Positives = 254/647 (39%), Gaps = 56/647 (8%)
Query: 386 QAENELNIEECQQEINE-----DEKAVEQYEQEMDELSQKITKLQKQT-AKLKEKEMIEE 439
Q +N +++ E + I+ DE+ E +Q D LS K+ L K+ + L++ +
Sbjct: 1382 QLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQD-LSFKVDTLSKEKISALEQVDDWSN 1440
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVP-------EKDFAVTINKFECEVRNEVXXXXXX 492
+K+ +H+ + EL + EKD + + K E + +N+
Sbjct: 1441 KFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNK--RFDCL 1498
Query: 493 XXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI-YKACGTQPYDVTLSKYTTTVEKL 551
+E + ++ L + + + + ED I K + + L Y +
Sbjct: 1499 KGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE 1558
Query: 552 QDEQ-NVLQSSMFIINKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
E LQ + + ++K+ L N+ + ++E ++V K
Sbjct: 1559 HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSK 1618
Query: 609 LE--KVTED-LQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVD----VDTQIKTL 661
E K ED L+ SA K L K+ +KI +K + Q+E++ ++ + L
Sbjct: 1619 EEELKALEDRLESESAAKLAELKRKA-EQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEL 1677
Query: 662 NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT 721
N ++E + E+K+ + + + ++ R + + T++ EA + C E
Sbjct: 1678 NTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEK 1737
Query: 722 LDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
+ V + K+K L RV +++ + + +++ Y+++ E Q + Q +
Sbjct: 1738 ISVLQRNLTE-KEK---LLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSM 1793
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
+ LQ + E K I+AK + D+ +
Sbjct: 1794 IG------HLQEELEEKNKKYSLIVAQHVEKEGG-KNNIQAKQNLENVFDDVQKTLQEKE 1846
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPR-EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
++ K+K LD+ + ++K V R EME++ +KL Q+ M R T+ ++
Sbjct: 1847 LTCQILEQKIKELDSCLV--RQKEVHRVEMEELTSKYEKLQALQQ--MDGRNKPTELLEE 1902
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+E +K + + L ++N + Q ++L KL G +E+ + ++ Q
Sbjct: 1903 NTEEKSKSHLVQPKL------------LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQ 1950
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYEL 1007
L + E L LKK R E K +D+E K + +L
Sbjct: 1951 KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 1997
Score = 35.1 bits (77), Expect = 1.5
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 7/155 (4%)
Query: 161 QEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQ 219
Q+D E ++ E + +D ++ + + + LK L+ + T + K+
Sbjct: 1950 QKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKE 2009
Query: 220 KELEDSYKKNTSFNKEEEKIANEKSSNEIEYN---KFILLESQNQEKIDKRNEQIVETAK 276
+ELE + K+ + NK +E A S++ E N K I + + ++ KR E+I++ +
Sbjct: 2010 QELEMTIKE--TINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE 2067
Query: 277 IAEIENITEVQTN-EEAENATKTILEKVESLKSDH 310
+ ++QT EE + + LE+ E+ +D+
Sbjct: 2068 EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDN 2102
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 81.0 bits (191), Expect = 2e-14
Identities = 196/1001 (19%), Positives = 419/1001 (41%), Gaps = 96/1001 (9%)
Query: 54 TGQMPPGSRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK--VTALAKKKTK 111
T + P S E V D ++ E L Q + N + E +S K T L +K
Sbjct: 290 TKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEA 349
Query: 112 FQT-LDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDE 170
Q LD L ++ K KD+ A+ L+ +L +K ++ + ++D + E
Sbjct: 350 LQEQLDERLQELE---KIKDL--HMAEKTKLI-TQLRDAKNLIEQL----EQDKGMVIAE 399
Query: 171 GKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K+ E+ + ++ + R+K++ Q +L E + +A +ELE +
Sbjct: 400 TKRQMHETLEMKE-EEIAQLRSRIKQMT---TQGEELREQKEKSERAAFEELEKALSTAQ 455
Query: 231 SFNKEEEKIANEKSSNEIEYNKFILLESQN-QEKIDKRNEQIVETAKIAEIENITEVQTN 289
+ K+ E K E + Q+++ + +++V+ K + E I ++Q
Sbjct: 456 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 515
Query: 290 EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXX 349
E E A K + L + ++ + E+ K A +++ +S + +
Sbjct: 516 HEKELARKE-----QELTKKLQTREREFQEQMKVA---LEKSQSEYLKISQEKEQQESLA 567
Query: 350 XXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQ 409
I + +++ ++ E +++E + N+ +
Sbjct: 568 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK---NQSKDLAVH 624
Query: 410 YEQEMDELSQKITKL-QKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPE 468
E E ++ +++IT + +K +L+ + ++ L T++ Q VLK +++T + +L +
Sbjct: 625 LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ--VLKQQYQTEMEKLREKCEQ 682
Query: 469 KDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI 528
+ + +K E+ L+ ++ + ESL+ SE+ KA K+
Sbjct: 683 EKETLLKDK-------EIIFQAHIEEMNEKTLEKLDVKQTEL-ESLSSELSEVLKARHKL 734
Query: 529 YKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM-FIINKYKGQLK--DNSCCPLCNRGF 585
+ D T K+ +++N Q + II +++ ++ + + N+
Sbjct: 735 EEELSVLK-DQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 793
Query: 586 ENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIP 645
E N+ +++ +LQ+ASAK D S +S + T + ++
Sbjct: 794 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 853
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDR----YIQEIK 700
QL+++++D++T+ L + V E+ + ++ K Q+ M L++ Q++K
Sbjct: 854 QLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK 913
Query: 701 TVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL 760
++T+ +E+ K + G+ + E T + K+ Q + ++ +KL+A + L
Sbjct: 914 SLTQVYES-KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHIL 972
Query: 761 YEK-KTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEK 819
E+ +TK K + +K Q ++E+ K+ D T LE++ KEK
Sbjct: 973 NEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLD----QEAKLKKELENTALELSQKEK 1028
Query: 820 IEAKTEVVRRNRDLIEAGSAYI--AKVEVAFNKVKSLDAEIQQHKK----------KNVP 867
+ + ++ +A SA I A + N+ + +++ + H++ K +
Sbjct: 1029 -----QFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLN 1083
Query: 868 REMEKIQEAND-KLMEKQKQIM----------TDRQVLTKKIDTLKDEIAKQEVYKRDLD 916
++ E++QE ++ +L EK++++ +++ + K+I LK+E KQ+ +L
Sbjct: 1084 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQ 1143
Query: 917 DNLCLRKAQT-----DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECT 971
+ L + A D T + ++L LN KE +E L+ + + K + +
Sbjct: 1144 EQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVS 1203
Query: 972 GALSELK------KSLKGFRNELEKSL-SKDIE-KKFREKM 1004
S+LK +SLK + KSL K +E KK E++
Sbjct: 1204 ELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1244
Score = 75.4 bits (177), Expect = 1e-12
Identities = 108/460 (23%), Positives = 209/460 (45%), Gaps = 37/460 (8%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTE--IPQLE--KRIVDVDTQIK---TLN 662
E++ E LQ KD L M + IT L+D + I QLE K +V +T+ + TL
Sbjct: 352 EQLDERLQELEKIKD--LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 409
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-----IKTVTKKFEAVKEQCGDVD 717
EEI +Q T +++ +R E + T K EA ++ ++D
Sbjct: 410 MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMD 469
Query: 718 SEMTLDVATAKQ--VDFKQKISTLRNRVKTTQKKLNAHN-KKLQTLYEKKTKAKEELLNT 774
++ T+++ + +Q++S ++ V KK + KLQ L+EK+ KE+ L
Sbjct: 470 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTK 529
Query: 775 QKKVQDIVNLEESKKQLQ-SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
+ + ++ E+ K L+ S LE +K TE + RDL
Sbjct: 530 KLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDL 589
Query: 834 IEAGSAYIAKV-EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
+ Y ++ E+ + KSL Q K V E EK + N ++ ++ T+ +
Sbjct: 590 QQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEK-NKHNKEITVMVEKHKTELE 648
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK--LNGINKEEL 950
L + D L E K +V K+ + + + + Q+++ L +K + + EE+
Sbjct: 649 SLKHQQDALWTE--KLQVLKQQYQTEMEKLREKCE----QEKETLLKDKEIIFQAHIEEM 702
Query: 951 NEK--ESLIIKQTKLFQQKAECTGALS---ELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
NEK E L +KQT+L +E + L +L++ L +++ +K + +++E K E+
Sbjct: 703 NEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDK-MKQELEAKMDEQ-- 759
Query: 1006 ELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
+ H + +D I+E+ V++ + ++++ + ++++E
Sbjct: 760 KNHHQQQVDSIIKEHEVSIQRTEKAL-KDQINQLELLLKE 798
Score = 48.0 bits (109), Expect = 2e-04
Identities = 97/578 (16%), Positives = 234/578 (40%), Gaps = 55/578 (9%)
Query: 386 QAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTK 444
QA E E+ ++++ + +E E+ E+ + KL+++ + LK++ + +++ L+ K
Sbjct: 696 QAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAK 755
Query: 445 EKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLE 504
+ KN H+ + ++ K+ V+I + E +++++ +
Sbjct: 756 MDE---QKNHHQQQVDSII-----KEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQ 807
Query: 505 AERKHIRESLNERRSELTKAEDK--IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
A +++ + EL +A K ++++ + ++ T Y + +LQ + L++
Sbjct: 808 AHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQT-KAYEEQLAQLQQKLLDLETER 866
Query: 563 FIINKYKGQL---KDNSCCPLCNRGF-------ENESEXXXXXXXXXXXXMNVPGKLEKV 612
++ K ++ K + C L + E + KLE
Sbjct: 867 ILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDG 926
Query: 613 TEDLQRAS----AKKDEILSMKSLNEKITTLKDTEIPQLEKRI----VDVDTQIKTLNET 664
++ ++ K++ IL M+ +K + ++ E I + +T+ K +
Sbjct: 927 NKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 986
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ----EIKTVTKKFEAVKEQCGDVDSEM 720
+E++ E ++ T K++ L + ++ E+ K+F A + +S
Sbjct: 987 MEKVKQKAKEMQE--TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAG 1044
Query: 721 TLDVATAKQVDFKQKIST--------LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D + + + K++I + L + + +KKLN ++LQ ++E + + KE+ +
Sbjct: 1045 ISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEV 1104
Query: 773 NTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
K Q I+ K+++ + + L+ LK+K + +
Sbjct: 1105 AELK--QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETK 1162
Query: 833 LIEAGSAYIAKVEVAFNKVKSLDAEIQQ---HKKKNVPREMEKIQEANDKLMEKQKQIMT 889
L A++ K+EV NK + +Q+ K + K+ E KL ++ +
Sbjct: 1163 L----KAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1218
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDL--DDNLCLRKAQ 925
+ K +L+D+ + + +L ++C +K +
Sbjct: 1219 LKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTE 1256
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 80.6 bits (190), Expect = 3e-14
Identities = 196/1001 (19%), Positives = 417/1001 (41%), Gaps = 96/1001 (9%)
Query: 54 TGQMPPGSRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK--VTALAKKKTK 111
T + P S E V D ++ E L Q + N + E +S K T L +K
Sbjct: 114 TKEENPESDGEPVVEDGASVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEA 173
Query: 112 FQT-LDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDE 170
Q LD L ++ K KD+ A+ L+ +L +K ++ + ++D + E
Sbjct: 174 LQEQLDERLQELE---KIKDL--HMAEKTKLI-TQLRDAKNLIEQL----EQDKGMVIAE 223
Query: 171 GKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K+ E+ + ++ + R+K++ Q +L E + +A +ELE +
Sbjct: 224 TKRQMHETLEMKE-EEIAQLRSRIKQMT---TQGEELREQKEKSERAAFEELEKALSTAQ 279
Query: 231 SFNKEEEKIANEKSSNEIEYNKFILLESQN-QEKIDKRNEQIVETAKIAEIENITEVQTN 289
+ K+ E K E + Q+++ + +++V+ K + E I ++Q
Sbjct: 280 KTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 339
Query: 290 EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXX 349
E E A K + L + ++ + E+ K A +++ +S + +
Sbjct: 340 HEKELARKE-----QELTKKLQTREREFQEQMKVA---LEKSQSEYLKISQEKEQQESLA 391
Query: 350 XXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQ 409
I + +++ ++ E +++E + N+ +
Sbjct: 392 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENE---NQSKDLAVH 448
Query: 410 YEQEMDELSQKITKL-QKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPE 468
E E ++ +++IT + +K +L+ + ++ L +E Q VLK +++T + +L +
Sbjct: 449 LEAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQ--VLKQQYQTEMEKLREKCEQ 506
Query: 469 KDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI 528
+ + +K E+ L+ + + ESL+ SE+ KA K+
Sbjct: 507 EKETLLKDK-------EIIFQAHIEEMNEKTLEKLDVNQTEL-ESLSSELSEVLKARHKL 558
Query: 529 YKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM-FIINKYKGQLK--DNSCCPLCNRGF 585
+ D T K+ +++N Q + II +++ ++ + + N+
Sbjct: 559 EEELSVLK-DQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 617
Query: 586 ENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIP 645
E N+ +++ +LQ+ASAK D S +S + T + ++
Sbjct: 618 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLA 677
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDR----YIQEIK 700
QL+++++D++T+ L + V E+ + ++ K Q+ M L++ Q++K
Sbjct: 678 QLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK 737
Query: 701 TVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL 760
++T+ +E+ K + G+ + E T + K+ Q + ++ +KL+A + L
Sbjct: 738 SLTQVYES-KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHIL 796
Query: 761 YEK-KTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEK 819
E+ +TK K + +K Q ++E+ K+ D T LE++ KEK
Sbjct: 797 NEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLD----QEAKLKKELENTALELSQKEK 852
Query: 820 IEAKTEVVRRNRDLIEAGSAYI--AKVEVAFNKVKSLDAEIQQHKK----------KNVP 867
+ + ++ +A SA I A + N+ + +++ + H++ K +
Sbjct: 853 -----QFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLN 907
Query: 868 REMEKIQEAND-KLMEKQKQIM----------TDRQVLTKKIDTLKDEIAKQEVYKRDLD 916
++ E++QE ++ +L EK++++ +++ + K+I LK+E KQ+ +L
Sbjct: 908 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQ 967
Query: 917 DNLCLRKAQT-----DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECT 971
+ L + A D T + ++L LN KE +E L+ + + K + +
Sbjct: 968 EQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVS 1027
Query: 972 GALSELK------KSLKGFRNELEKSL-SKDIE-KKFREKM 1004
S+LK +SLK + KSL K +E KK E++
Sbjct: 1028 ELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEEL 1068
Score = 71.3 bits (167), Expect = 2e-11
Identities = 108/461 (23%), Positives = 208/461 (45%), Gaps = 39/461 (8%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTE--IPQLE--KRIVDVDTQIK---TLN 662
E++ E LQ KD L M + IT L+D + I QLE K +V +T+ + TL
Sbjct: 176 EQLDERLQELEKIKD--LHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 233
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-----IKTVTKKFEAVKEQCGDVD 717
EEI +Q T +++ +R E + T K EA ++ ++D
Sbjct: 234 MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMD 293
Query: 718 SEMTLDVATAKQ--VDFKQKISTLRNRVKTTQKKLNAHN-KKLQTLYEKKTKAKEELLNT 774
++ T+++ + +Q++S ++ V KK + KLQ L+EK+ KE+ L
Sbjct: 294 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTK 353
Query: 775 QKKVQDIVNLEESKKQLQ-SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
+ + ++ E+ K L+ S LE +K TE + RDL
Sbjct: 354 KLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDL 413
Query: 834 IEAGSAYIAKV-EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
+ Y ++ E+ + KSL Q K V E EK + N ++ ++ T+ +
Sbjct: 414 QQEAETYRTRILELESSLEKSLQENENQSKDLAVHLEAEK-NKHNKEITVMVEKHKTELE 472
Query: 893 VLTKKIDTLKDE---IAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
L + D L E + KQ+ Y+ +++ LR+ +D E+ + + EE
Sbjct: 473 SLKHQQDALWAEELQVLKQQ-YQTEMEK---LREKCEQEKETLLKDKEI---IFQAHIEE 525
Query: 950 LNEK--ESLIIKQTKLFQQKAECTGALS---ELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
+NEK E L + QT+L +E + L +L++ L +++ +K + +++E K E+
Sbjct: 526 MNEKTLEKLDVNQTELESLSSELSEVLKARHKLEEELSVLKDQTDK-MKQELEAKMDEQ- 583
Query: 1005 YELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
+ H + +D I+E+ V++ + ++++ + ++++E
Sbjct: 584 -KNHHQQQVDSIIKEHEVSIQRTEKAL-KDQINQLELLLKE 622
Score = 59.7 bits (138), Expect = 6e-08
Identities = 165/921 (17%), Positives = 367/921 (39%), Gaps = 97/921 (10%)
Query: 189 DCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEI 248
+ +D +KK ++ Q KL + + + K++EL + +E+ K+A EKS +E
Sbjct: 320 EVVDVMKKSSEE--QIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSE- 376
Query: 249 EYNKFILLESQNQEKIDKRNEQIVETAKIAEIEN-ITEVQTNEEA--------ENATKTI 299
Y K I E + QE + ++ + A + E EN + ++Q E E++ +
Sbjct: 377 -YLK-ISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 434
Query: 300 LEKVESLKSDHKVQ-KSQADEEEKKAQGFVDECRSG-HTQXXXXXXXXXXXXXXXXXXXX 357
L++ E+ D V +++ ++ K+ V++ ++ +
Sbjct: 435 LQENENQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWAEELQVLKQQYQ 494
Query: 358 XDITSANQS-XXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDE 416
++ + H + NE +E+ ++N+ E +E E+ E
Sbjct: 495 TEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKL--DVNQTE--LESLSSELSE 550
Query: 417 LSQKITKLQKQTAKLKEK-EMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTI 475
+ + KL+++ + LK++ + +++ L+ K + KN H+ + ++ K+ V+I
Sbjct: 551 VLKARHKLEEELSVLKDQTDKMKQELEAKMDE---QKNHHQQQVDSII-----KEHEVSI 602
Query: 476 NKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK--IYKACG 533
+ E +++++ +A +++ + EL +A K ++++
Sbjct: 603 QRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ 662
Query: 534 TQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQL---KDNSCCPLCNRGF----- 585
+ ++ T Y + +LQ + L++ ++ K ++ K + C L
Sbjct: 663 SATHEQT-KAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 721
Query: 586 --ENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS----AKKDEILSMKSLNEKITTL 639
+ E + KLE ++ ++ K++ IL M+ +K +
Sbjct: 722 MQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEI 781
Query: 640 KDTEIPQLEKRI----VDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRY 695
++ E I + +T+ K + +E++ E ++ T K++ L +
Sbjct: 782 LTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQE--TLKKKLLDQEAKLKKE 839
Query: 696 IQ----EIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST--------LRNRV 743
++ E+ K+F A + +S D + + + K++I + L + +
Sbjct: 840 LENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVI 899
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXX 803
+KKLN ++LQ ++E + + KE+ + K Q I+ K+++ +
Sbjct: 900 SIWEKKLNQQAEELQEIHEIQLQEKEQEVAELK--QKILLFGCEKEEMNKEITWLKEEGV 957
Query: 804 XXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ--- 860
+ L+ LK+K + + L A++ K+EV NK + +Q+
Sbjct: 958 KQDTTLNELQEQLKQKSAHVNSLAQDETKL----KAHLEKLEVDLNKSLKENTFLQEQLV 1013
Query: 861 HKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC 920
K + K+ E KL ++ + + K +L+D+ + + +L L
Sbjct: 1014 ELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLD 1073
Query: 921 LRKAQTDITNWQKQDDELN---EKLNGI-------NKEELNEKESLIIKQ---TKLFQQK 967
+ +T+ K ++ +N K N I KE+L+IK ++L Q
Sbjct: 1074 ICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQL 1133
Query: 968 AECTGALSELKKSLKGFRNELE------KSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ T + L S + ++LE KS+ DIE EK + + ++ A
Sbjct: 1134 RQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEK----EALQKEGGNQQQAA 1189
Query: 1022 VALDKCLMEFHREKMENINMI 1042
+ C+ + +E ENIN +
Sbjct: 1190 SEKESCITQLKKELSENINAV 1210
Score = 55.2 bits (127), Expect = 1e-06
Identities = 167/831 (20%), Positives = 338/831 (40%), Gaps = 98/831 (11%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQN---QEKIDKRNEQI 271
++ + E+E K T E K+ E + E E K IL+E +N Q + ++ E
Sbjct: 725 LEKQNSEMEQKVKSLTQVY--ESKL--EDGNKEQEQTKQILVEKENMILQMREGQKKEIE 780
Query: 272 VETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDEC 331
+ T K++ E+ + NEE E K +K+E +K QK++ +E K + E
Sbjct: 781 ILTQKLSAKEDSIHI-LNEEYETKFKNQEKKMEKVK-----QKAKEMQETLKKKLLDQEA 834
Query: 332 RSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENEL 391
+ + ++ AN + ++ E+
Sbjct: 835 KL--KKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQI--ESLTEV 890
Query: 392 NIEECQQEINEDEKAVEQYEQEMDELSQ-KITKLQKQTAKLKEKEMIEENLKTKEKQLIV 450
+ E I+ EK + Q +E+ E+ + ++ + +++ A+LK+K ++ +++++
Sbjct: 891 HRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILL---FGCEKEEM-- 945
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
NK T L E ++D T+N E++ ++ L+A + +
Sbjct: 946 --NKEITWLKE---EGVKQD--TTLN----ELQEQLKQKSAHVNSLAQDETKLKAHLEKL 994
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVT-LSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
LN+ E T ++++ + D +S+ T+ ++ +E L+SS NK
Sbjct: 995 EVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK-- 1052
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR-ASAKKDEILS 628
L+D S F+ SE LE T +L +S+K + ILS
Sbjct: 1053 -SLEDKSL------EFKKLSEELAIQLDICCK--KTEALLEAKTNELINISSSKTNAILS 1103
Query: 629 MKSLNEKITT-------LKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT 681
S + TT +K + +LE ++ + + TLN + ++ T L E+K
Sbjct: 1104 RISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQL---EEKENQ 1160
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRN 741
K + D+ L VT+K EA++++ G+ + + Q+ K+++S N
Sbjct: 1161 IKSMKADIESL---------VTEK-EALQKEGGNQQQAASEKESCITQL--KKELSENIN 1208
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXX 801
V +++L ++ +L ++ T +L N+ + + +KQ +
Sbjct: 1209 AVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQ 1268
Query: 802 XXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
+ L KEKI A +V + E ++ N VK L +++
Sbjct: 1269 VQDLSFKVDTLS---KEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELK 1325
Query: 862 KKKNVPRE------MEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
K+ ++ E++ + N + + ++ D+ + KK L+ E+ Q +L
Sbjct: 1326 SKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMEL 1385
Query: 916 DDNLCLRKAQTD-----ITNWQKQDD----ELNEKL---NGINKEELNE----KESLIIK 959
+D++ + + + + N+ +Q D EL +KL + +E+ N +E ++
Sbjct: 1386 EDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1445
Query: 960 QTKLFQQKAECTGALSELKK---SLKGFRNELEKSLSKDIEKKFREKMYEL 1007
+ +++ KAE EL+ S+K EL K+L +E + K+ EL
Sbjct: 1446 ENQVYSMKAELETKKKELEHVNLSVKSKEEEL-KALEDRLESESAAKLAEL 1495
Score = 51.6 bits (118), Expect = 2e-05
Identities = 126/647 (19%), Positives = 254/647 (39%), Gaps = 56/647 (8%)
Query: 386 QAENELNIEECQQEINE-----DEKAVEQYEQEMDELSQKITKLQKQT-AKLKEKEMIEE 439
Q +N +++ E + I+ DE+ E +Q D LS K+ L K+ + L++ +
Sbjct: 1237 QLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQD-LSFKVDTLSKEKISALEQVDDWSN 1295
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVP-------EKDFAVTINKFECEVRNEVXXXXXX 492
+K+ +H+ + EL + EKD + + K E + +N+
Sbjct: 1296 KFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNK--RFDCL 1353
Query: 493 XXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI-YKACGTQPYDVTLSKYTTTVEKL 551
+E + ++ L + + + + ED I K + + L Y +
Sbjct: 1354 KGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE 1413
Query: 552 QDEQ-NVLQSSMFIINKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
E LQ + + ++K+ L N+ + ++E ++V K
Sbjct: 1414 HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSK 1473
Query: 609 LE--KVTED-LQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVD----VDTQIKTL 661
E K ED L+ SA K L K+ +KI +K + Q+E++ ++ + L
Sbjct: 1474 EEELKALEDRLESESAAKLAELKRKA-EQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEL 1532
Query: 662 NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT 721
N ++E + E+K+ + + + ++ R + + T++ EA + C E
Sbjct: 1533 NTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEK 1592
Query: 722 LDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
+ V + K+K L RV +++ + + +++ Y+++ E Q + Q +
Sbjct: 1593 ISVLQRNLTE-KEK---LLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSM 1648
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
+ LQ + E K I+AK + D+ +
Sbjct: 1649 IG------HLQEELEEKNKKYSLIVAQHVEKEGG-KNNIQAKQNLENVFDDVQKTLQEKE 1701
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPR-EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
++ K+K LD+ + ++K V R EME++ +KL Q+ M R T+ ++
Sbjct: 1702 LTCQILEQKIKELDSCLV--RQKEVHRVEMEELTSKYEKLQALQQ--MDGRNKPTELLEE 1757
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+E +K + + L ++N + Q ++L KL G +E+ + ++ Q
Sbjct: 1758 NTEEKSKSHLVQPKL------------LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQ 1805
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYEL 1007
L + E L LKK R E K +D+E K + +L
Sbjct: 1806 KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 1852
Score = 35.1 bits (77), Expect = 1.5
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 7/155 (4%)
Query: 161 QEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQ 219
Q+D E ++ E + +D ++ + + + LK L+ + T + K+
Sbjct: 1805 QKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKE 1864
Query: 220 KELEDSYKKNTSFNKEEEKIANEKSSNEIEYN---KFILLESQNQEKIDKRNEQIVETAK 276
+ELE + K+ + NK +E A S++ E N K I + + ++ KR E+I++ +
Sbjct: 1865 QELEMTIKE--TINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE 1922
Query: 277 IAEIENITEVQTN-EEAENATKTILEKVESLKSDH 310
+ ++QT EE + + LE+ E+ +D+
Sbjct: 1923 EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDN 1957
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 80.6 bits (190), Expect = 3e-14
Identities = 204/1036 (19%), Positives = 410/1036 (39%), Gaps = 106/1036 (10%)
Query: 69 DAKVNRSTEVLGQVKLKIVNAK-DKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGK 127
D K N + Q +L+++ + KQ E+ K A+ K+ +T D L+ V+E K
Sbjct: 1052 DLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDR-LAEVEEKLK 1110
Query: 128 TKDVSSRCADLDIL-MHEELGVSKAILNSVVFCHQEDSSWPL----------DEGKKVKE 176
K + +L + EE+ + +N + E + L + +K+ E
Sbjct: 1111 EKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNE 1170
Query: 177 RFDEIFDADKYSDCLDRLKKIRKDYAQNLK--LLENYATTVKAKQKELEDSY---KKNTS 231
++E+ K L L+K + +L+ + E AT ++ K+ EL+ ++ K++
Sbjct: 1171 NYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE-ELKIAHIHLKEHQE 1229
Query: 232 FNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQ------IVETAKIAEIENITE 285
E + +EK++ I ++ QE+I +E+ + E ++ E N E
Sbjct: 1230 TIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELE 1289
Query: 286 VQTNEEAENATKTILE-KVESLKSDHKVQKSQAD-----EEEKKAQGFVDECRSGHTQXX 339
+ T + + T+ ++E L+ + K Q+SQ + +E + + H Q
Sbjct: 1290 LLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLK 1349
Query: 340 XXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQE 399
+ + E+ + +
Sbjct: 1350 EHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKR 1409
Query: 400 INEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE--KEMIEENLKTKEKQLIV---LKNK 454
+ E ++ +E D+L + LQ ++ +LKE KE++ ++L+T+E+ + LK +
Sbjct: 1410 LQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQ 1469
Query: 455 HKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESL 514
+T + EL N+ EK+ ++ + + E N+ ++ + ++E +
Sbjct: 1470 EET-INELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIK-QISEVQEKV 1527
Query: 515 NERRS--ELTKAEDKIYKACGTQPYDVT--LSKYTTTVEKLQDEQNVLQSSMFIINKYKG 570
NE + E KA+D ++ ++ ++T L + ++ + E+ ++ + +
Sbjct: 1528 NELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERD 1587
Query: 571 QLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKV-----TEDLQRASAKKDE 625
QLK+N+ + E E ++E + T+ L + + +
Sbjct: 1588 QLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETEN 1647
Query: 626 ILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT--LNETVEE-ITMSLIEPEQKMTTA 682
I + L+E + ++ + + R V+ +++ L E + E IT L + E+
Sbjct: 1648 IRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVH 1707
Query: 683 KQIHGDMPMLDRY-------IQEIKTVTKKFE----AVKEQCGDVDSEMTLDVATAKQ-- 729
+ +D+ EI + K E A+K Q + E+ + K+
Sbjct: 1708 MHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQ 1767
Query: 730 --VD-FKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKA------KEELLNTQKKVQ 779
+D + +S +++ QK L N KLQ + E K K+++ TQKKV
Sbjct: 1768 ETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVS 1827
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN-RDLIEAGS 838
+ +E+ KKQ++ L L+E E R N R + E
Sbjct: 1828 E---MEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKE--RDNLRRVEETLK 1882
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+++ + + K+ D EIQQ + K ++ +E DKL EK + + K +
Sbjct: 1883 LERDQLKESLQETKARDLEIQQ-ELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDL 1941
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLII 958
D KDE+ K K+D ++ + + Q + L EK + I + ++
Sbjct: 1942 DKSKDELQK----KQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKE---------LL 1988
Query: 959 KQTKLFQQKAECTGALS-ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDI 1017
K+ EC LS +L+K ++ F+ EL + ++ + + TK I+K
Sbjct: 1989 KRYSEMDDHYECLNRLSLDLEKEIE-FQKELSMRVKANLSLPYLQ-------TKHIEK-- 2038
Query: 1018 REYAVALDKCLMEFHR 1033
A +C MEFHR
Sbjct: 2039 --LFTANQRCSMEFHR 2052
Score = 77.8 bits (183), Expect = 2e-13
Identities = 182/1022 (17%), Positives = 407/1022 (39%), Gaps = 63/1022 (6%)
Query: 93 QLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKT-KDV------SSRCADLDILMHEE 145
QLE + M+V + ++ F + S +D GK KD+ + DL +++E
Sbjct: 655 QLEAKKKMQVDLEKELQSAFNEITKLTSLID--GKVPKDLLCNLELEGKITDLQKELNKE 712
Query: 146 LGVSKAILNSVVFCHQEDSSWPLDEG---KKVKERFDEIF----DADK-YSDCLDRLKKI 197
+ ++A+ V+ E S P + K+++++ +E+ + DK +S+ + + ++
Sbjct: 713 VEENEALREEVILL-SELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRV 771
Query: 198 RKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKE-EEKIANEKSSNEIEYNKFILL 256
+ + K ++ ATT ++ K + ++ + + + E+K NE N+ I+
Sbjct: 772 QGLLEEIGKTKDDLATT-QSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENE-RMNQEIVN 829
Query: 257 ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQ 316
S+ +K D + E + + +E N + + E++E+ S + + +
Sbjct: 830 LSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVERE 889
Query: 317 ADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXX 376
+K Q ++E ++ TQ DI
Sbjct: 890 KTLITEKLQQTLEEVKT-LTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRN 948
Query: 377 XXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKL-QKQTAKLKEKE 435
H++ N L + +E++ + E + DE QK+ + +KQ + K +
Sbjct: 949 ALESLKQHQETINTLK-SKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQ 1007
Query: 436 MIEENLKTKE----KQLIVLKNKHKTALMELLGNV-PEKDFAVTINKFECEVRNEVXXXX 490
+ ++K E ++ I + K L ++L +V EK+ T K E+ E
Sbjct: 1008 TLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEEL 1067
Query: 491 XXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGT-QPYDVTLSKYTTTVE 549
+ A+ K+ ++ EL++ D++ + + L + +
Sbjct: 1068 RLLGDELKKQQEIVAQEKN---HAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLL 1124
Query: 550 KLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKL 609
+Q+E + +Q + I K +LK+ L E E + K
Sbjct: 1125 NVQEEMSEMQKKINEIENLKNELKNKE---LTLEHMETERLELAQKLNENYEEVKSITKE 1181
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
KV ++LQ++ + + L + T L+ E E +I + +K ET++E+
Sbjct: 1182 RKVLKELQKSFETERDHLRGYIREIEATGLQTKE----ELKIAHI--HLKEHQETIDELR 1235
Query: 670 MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ 729
S+ E ++ + + L I + + VKE ++ L++ T +
Sbjct: 1236 RSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQS 1295
Query: 730 VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKK 789
K ST R++ + +LN ++ Q + TK ++ L ++ ++ V ++ K+
Sbjct: 1296 TT---KDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALE--VKHDQLKE 1350
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF- 848
++ ++ +KEK T++V SA + ++E+
Sbjct: 1351 HIRETLAKIQESQSKQEQSLN-----MKEKDNETTKIVSEMEQFKPKDSALL-RIEIEML 1404
Query: 849 ---NKVKSLDAEIQQ--HKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD 903
+++ E++ +K ++ R E +Q +D+L E K+I+ +++
Sbjct: 1405 GLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHC 1464
Query: 904 EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKL 963
+ +QE +L NL + +T+I+ QKQ + +N+KL +E ++E IKQ
Sbjct: 1465 CLKEQEETINELRVNLS--EKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1522
Query: 964 FQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVA 1023
Q+K E +K+ +E + ++ + +E E+ + ++++ A
Sbjct: 1523 VQEKVNELKQFKEHRKAKDSALQSIESKM-LELTNRLQESQEEIQIMIKEKEEMKRVQEA 1581
Query: 1024 LDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQS 1083
L + + +E + I ++E K Y+ + + E +E + +++ + +
Sbjct: 1582 L-QIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNL 1640
Query: 1084 KN 1085
+N
Sbjct: 1641 EN 1642
Score = 66.9 bits (156), Expect = 4e-10
Identities = 155/742 (20%), Positives = 303/742 (40%), Gaps = 82/742 (11%)
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
AE E ++E Q++ E ++ + ++EM E+ +KI +++ +LK KE+ E++ E
Sbjct: 1103 AEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHM---ET 1159
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINK-FECE---VRNEVXXXXXXXXXXXXXXXX 502
+ + L K E+ E+ + K FE E +R +
Sbjct: 1160 ERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKI 1219
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQD------EQN 556
K +E+++E R +++ +I + L + + + Q+ E +
Sbjct: 1220 AHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVS 1279
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLC---------NRGFENESEXXXXXXXXXXXXMNVPG 607
Q +M + Q L N F+ E +
Sbjct: 1280 ETQETMNELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKE 1339
Query: 608 KLE----KVTEDLQRASAKKDEILSMK--SLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
LE ++ E ++ AK E S + SLN K + T+I ++ D+ + +
Sbjct: 1340 ALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRI 1399
Query: 662 NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGD-VDSEM 720
+ ++ L E +M + + D+ L +Q K E +KE +++E
Sbjct: 1400 EIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLK--ENIKEIVAKHLETEE 1457
Query: 721 TLDVATAKQVDFKQKISTLR-------NRVKTTQKKLNAHNKKLQT----LYEKKTKAK- 768
L VA + ++ I+ LR + T QK+L A N KLQ +YEK+ +
Sbjct: 1458 ELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNI 1517
Query: 769 EELLNTQKKVQDIVNLEESKKQ----LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
+++ Q+KV ++ +E +K LQS + +++ +KEK E K
Sbjct: 1518 KQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKR 1577
Query: 825 --EVVRRNRD-LIEAGSAYIAKVE------------VAFNKVKSLDAEIQQHKKKNVPRE 869
E ++ RD L E +AK++ A N+ + EI+ K++ ++
Sbjct: 1578 VQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQK 1637
Query: 870 M--EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD 927
+ E I+ N +L + + + + + +TK+ D L+ +V + L +N LR+ T
Sbjct: 1638 LNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKEN--LRETIT- 1694
Query: 928 ITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+D E E+L ++ L E + I K + +K T +S ++K L+ N+
Sbjct: 1695 ------RDLEKQEELKIVHM-HLKEHQETIDKLRGIVSEK---TNEISNMQKDLE-HSND 1743
Query: 988 LEKSLSKDIEKKFR-EKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIREL 1046
K+ I+++ R M+ + IDK + DK + ++ +EN N ++E
Sbjct: 1744 ALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDK--LSNMQKDLENSNAKLQEK 1801
Query: 1047 WRKIYRGNDIDYIEIKTEGNLT 1068
+++ + N+ I +K + N T
Sbjct: 1802 IQEL-KANEHQLITLKKDVNET 1822
Score = 52.8 bits (121), Expect = 7e-06
Identities = 110/615 (17%), Positives = 255/615 (41%), Gaps = 48/615 (7%)
Query: 389 NELNIEECQQEINEDEKAVEQYEQ---EMDELSQKITKLQKQTAKLKEKEMIEENLKTKE 445
NE + ++++NE +K V + EQ ++ + S ++KL+ + L +K + ENL+ +
Sbjct: 1808 NEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQK--LHENLEEMK 1865
Query: 446 KQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEA 505
+ N + L K+ + E++ E+ L
Sbjct: 1866 SVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLRE 1925
Query: 506 ERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTT--VEKLQDEQNVLQSSMF 563
+ +++ + +L K++D++ K Q + V K + + L + S +
Sbjct: 1926 KISEKTIQISDIQKDLDKSKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIK 1985
Query: 564 IINKYKGQLKDN-SCCPLCNRGFENESEXXXXXXXXXXXXMNVP----GKLEKVTEDLQR 618
+ K ++ D+ C + E E E +++P +EK+ QR
Sbjct: 1986 ELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQR 2045
Query: 619 ASAKKDEILS-MKSLNEKITTLKDTE---IPQLEKRIVDVDTQIKTLNETVEEITMSLIE 674
S + I+ +K + +T +K+ + I + E +D + K L ++ +
Sbjct: 2046 CSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDV 2105
Query: 675 PEQKMTTAKQIHGDMPMLDRYIQEI-KTVTK-KFEAVKEQCGDV-DSEMTLDVATAKQVD 731
P +++ K ++ +M D +I+EI K ++ +F ++K + V + + + ++
Sbjct: 2106 PSRELRDLK-LNQNM---DLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLN 2161
Query: 732 FKQKISTLRNRVKTTQKKL----NAHNKKLQTLYEKKTKAKEELLNTQKK-VQDIVNLEE 786
+ I L+N ++ ++ N N ++ + + T+ +E K+ QD+ +L+E
Sbjct: 2162 TRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKE 2221
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
++L + + P K V R L + I ++E
Sbjct: 2222 KNEKLFKN-YQTLKTSLASGAQVNPTTQDNKNP-----HVTSRATQLT---TEKIRELEN 2272
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK---KIDTLKD 903
+ ++ K E HK+ + + ++++ ND + + Q ++ + L K I L+D
Sbjct: 2273 SLHEAK----ESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQD 2328
Query: 904 EIA-KQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL-IIKQT 961
++A + YK +++D L ++ + D+ K E ++++ +KE + ++++
Sbjct: 2329 KVALGAKPYKEEIED-LKMKLVKIDLEK-MKNAKEFEKEISATKATVEYQKEVIRLLREN 2386
Query: 962 KLFQQKAECTGALSE 976
Q+A+ T +SE
Sbjct: 2387 LRRSQQAQDTSVISE 2401
Score = 42.3 bits (95), Expect = 0.010
Identities = 39/190 (20%), Positives = 90/190 (47%), Gaps = 10/190 (5%)
Query: 736 ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKA----KEELLNTQKKVQDIVNLEESK--K 789
I+ L+ +V + K L + +Q L +K KEE+ + + K+ I +LE+ K K
Sbjct: 2302 IAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKI-DLEKMKNAK 2360
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAK-TEVVRRNRDLIEAGSAYIAKVEVAF 848
+ + + I L L+ +A+ T V+ + D +
Sbjct: 2361 EFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKPLTCGGGSGI 2420
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
V++ A I + + + +E+ K+++ N++L++++ +++++ Q L+ ++ T K+ K+
Sbjct: 2421 --VQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHLSNEVKTWKERTLKR 2478
Query: 909 EVYKRDLDDN 918
E +K+ +N
Sbjct: 2479 EAHKQVTCEN 2488
>AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protein
130d protein.
Length = 1135
Score = 78.2 bits (184), Expect = 2e-13
Identities = 113/594 (19%), Positives = 250/594 (42%), Gaps = 54/594 (9%)
Query: 424 LQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGN--VPEKDFAVTINKFECE 481
LQ+ + K E+ + +L + KHK + +LG V EK TI + E E
Sbjct: 119 LQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSHRQTILELEEE 178
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
R LE E + +++ +++ + E + K T ++T
Sbjct: 179 KRKH----KEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELT- 233
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX 601
K + + DEQ L + + + + +L N+ E
Sbjct: 234 -KLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNA------------KETHTKLALAEAR 280
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
K ++ ++LQ + K + ++ K+T +D++ QL++++ + QI L
Sbjct: 281 VQEEEQKATRLEKELQTQTTKFHQ--DQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDEL 337
Query: 662 NETVEEITMS---LIEPEQKMTTAKQ----IHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
ET + + L + ++K++ + I ++ L + + +++ ++ ++EQC
Sbjct: 338 EETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCR 397
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D++ + + +K DFK ++ L R+ +K +A NK Q Y K ++E + T
Sbjct: 398 DLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTT 455
Query: 775 QKKVQDIVNLEESKKQL---QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
++ Q++ +L+ K+L +S + L V ++ + +E +++
Sbjct: 456 KQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTE 515
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREMEKIQEANDKLMEKQK 885
D ++A S ++++V NKV ++ ++ + K+ +V +M + + D L K K
Sbjct: 516 DKLQAAS---SQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Query: 886 QIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGI 945
L +++ LK+ + E ++D N + + T ++++++ E +
Sbjct: 573 AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEV 632
Query: 946 NKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS--LSKDIE 997
+ +L K+ I+ + K E E + + + NE +K+ LSK++E
Sbjct: 633 ERLKLKLKDMKAIEDDLM---KTE-----DEYETLERRYANERDKAQFLSKELE 678
Score = 70.5 bits (165), Expect = 3e-11
Identities = 124/638 (19%), Positives = 267/638 (41%), Gaps = 53/638 (8%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+ E+++ ++Y ++ DE I L+++ +L K++I++ +K++E++ K K T
Sbjct: 174 ELEEEKRKHKEYMEKSDEF---ICLLEQECERL--KKLIDQEIKSQEEK-EQEKEKRVTT 227
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L E L + K FA+ + + + ++ + + E
Sbjct: 228 LKEELTKL--KSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEE 285
Query: 519 SELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQN-VLQSSMFIINKYKGQLKDN 575
+ T+ E ++ Q D ++K T +D QN LQ + +++ +L++
Sbjct: 286 QKATRLEKELQTQTTKFHQDQDTIMAKLTN-----EDSQNRQLQQKLAALSRQIDELEET 340
Query: 576 SCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM----KS 631
+ + E + + ++E++ + + K +E++ M +
Sbjct: 341 N--RSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRD 398
Query: 632 LNEKI--TTL--KD--TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQI 685
LN+++ TL KD E+ +L KRI+ ++ N++ +E E++ T KQ
Sbjct: 399 LNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ- 457
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK--QVDFKQKISTLRNRV 743
L + ++ +K K+ EA++ + + + D+ K V F + T+ ++
Sbjct: 458 ------LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKL 511
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELL-NTQKKVQDIVNLEE-------SKKQLQSDC 795
K T+ KL A + +LQ K T E+L+ T++ ++ ++EE + L++
Sbjct: 512 KKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKL 571
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
+ L+ L + +EA + +N+ ++G + A + NK+K L
Sbjct: 572 KAEEEKGNDLLSRVNMLKNRL-QSLEAIEKDFLKNKLNQDSGKSTTA-LHQENNKIKELS 629
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
E+++ K K ++M+ I+ D LM+ + + T + + D + + E K +L
Sbjct: 630 QEVERLKLK--LKDMKAIE---DDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMEL 684
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
K +T W + + E +G E++ + I + G S
Sbjct: 685 AKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHS 744
Query: 976 ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAI 1013
L+K L N + L ++IE +E H +K++
Sbjct: 745 VLQKKLNQQENR-NRDLGREIENLTKELERYRHFSKSL 781
Score = 38.3 bits (85), Expect = 0.16
Identities = 66/335 (19%), Positives = 141/335 (42%), Gaps = 25/335 (7%)
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
+H + + L E+K K KE + +K + I LE+ ++L+
Sbjct: 167 SHRQTILELEEEKRKHKEYM---EKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEK 223
Query: 812 LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREME 871
LKE++ T++ +++ A++ + K++ L ++ K E
Sbjct: 224 RVTTLKEEL---TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEA- 279
Query: 872 KIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD---I 928
++QE K +K++ T + DT+ ++ ++ R L L Q D
Sbjct: 280 RVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEE 339
Query: 929 TN--WQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
TN +K ++EL + I+K E ++ + +L ++ + G EL K + R
Sbjct: 340 TNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIKMEEQCR- 397
Query: 987 ELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINM---II 1043
+L K L ++ + K ++L V K + K I +AL+K F++ K E ++ +
Sbjct: 398 DLNKRLERE---TLQSKDFKLEVEK-LSKRI----MALEKLEDAFNKSKQECYSLKCNLE 449
Query: 1044 RELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDY 1078
+E +++ ++++ + +ES K ++
Sbjct: 450 KERMTTKQLSQELESLKVRIKELEAIESRLEKTEF 484
Score = 35.5 bits (78), Expect = 1.2
Identities = 72/393 (18%), Positives = 166/393 (42%), Gaps = 23/393 (5%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ + I EK + + + E L+K+ K+ E+LK + K+L
Sbjct: 414 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 473
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
++++ + L ++ K +T+ F E + L+ E+
Sbjct: 474 AIESRLEKTEFTLKEDL-TKLKTLTV-MFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 531
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ ++ E+ E TK K + Y VT + KL+ E+ + +N K
Sbjct: 532 V-TTVTEKLIEETKRALKSKTDVEEKMYSVTKER-DDLKNKLKAEEEKGNDLLSRVNMLK 589
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L+ S + +N+ N K+++++++++R K + M
Sbjct: 590 NRLQ--SLEAIEKDFLKNKLNQDSGKSTTALHQEN--NKIKELSQEVERLKLK---LKDM 642
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K++ + + +D E LE+R + + + L++ +E + M L + K+ + +
Sbjct: 643 KAIEDDLMKTED-EYETLERRYANERDKAQFLSKELEHVKMEL--AKYKLAEKTETSHEQ 699
Query: 690 PMLDR-YIQEIKT--VTKKFEAVKEQCGDVDSEMTLDVATAKQVD---FKQKISTLRNRV 743
+ R +E K+ ++++ +A+KE+ + + T D+ Q D ++K++ NR
Sbjct: 700 WLFKRLQEEEAKSGHLSREVDALKEKIHEYMA--TEDLICHLQGDHSVLQKKLNQQENRN 757
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
+ +++ K+L+ Y +K+ LN ++
Sbjct: 758 RDLGREIENLTKELER-YRHFSKSLRPSLNGRR 789
>AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protein
130b protein.
Length = 1133
Score = 78.2 bits (184), Expect = 2e-13
Identities = 113/594 (19%), Positives = 250/594 (42%), Gaps = 54/594 (9%)
Query: 424 LQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGN--VPEKDFAVTINKFECE 481
LQ+ + K E+ + +L + KHK + +LG V EK TI + E E
Sbjct: 119 LQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSHRQTILELEEE 178
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
R LE E + +++ +++ + E + K T ++T
Sbjct: 179 KRKH----KEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELT- 233
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX 601
K + + DEQ L + + + + +L N+ E
Sbjct: 234 -KLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNA------------KETHTKLALAEAR 280
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
K ++ ++LQ + K + ++ K+T +D++ QL++++ + QI L
Sbjct: 281 VQEEEQKATRLEKELQTQTTKFHQ--DQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDEL 337
Query: 662 NETVEEITMS---LIEPEQKMTTAKQ----IHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
ET + + L + ++K++ + I ++ L + + +++ ++ ++EQC
Sbjct: 338 EETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCR 397
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D++ + + +K DFK ++ L R+ +K +A NK Q Y K ++E + T
Sbjct: 398 DLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTT 455
Query: 775 QKKVQDIVNLEESKKQL---QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
++ Q++ +L+ K+L +S + L V ++ + +E +++
Sbjct: 456 KQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTE 515
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREMEKIQEANDKLMEKQK 885
D ++A S ++++V NKV ++ ++ + K+ +V +M + + D L K K
Sbjct: 516 DKLQAAS---SQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Query: 886 QIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGI 945
L +++ LK+ + E ++D N + + T ++++++ E +
Sbjct: 573 AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEV 632
Query: 946 NKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS--LSKDIE 997
+ +L K+ I+ + K E E + + + NE +K+ LSK++E
Sbjct: 633 ERLKLKLKDMKAIEDDLM---KTE-----DEYETLERRYANERDKAQFLSKELE 678
Score = 70.5 bits (165), Expect = 3e-11
Identities = 124/638 (19%), Positives = 267/638 (41%), Gaps = 53/638 (8%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+ E+++ ++Y ++ DE I L+++ +L K++I++ +K++E++ K K T
Sbjct: 174 ELEEEKRKHKEYMEKSDEF---ICLLEQECERL--KKLIDQEIKSQEEK-EQEKEKRVTT 227
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L E L + K FA+ + + + ++ + + E
Sbjct: 228 LKEELTKL--KSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEE 285
Query: 519 SELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQN-VLQSSMFIINKYKGQLKDN 575
+ T+ E ++ Q D ++K T +D QN LQ + +++ +L++
Sbjct: 286 QKATRLEKELQTQTTKFHQDQDTIMAKLTN-----EDSQNRQLQQKLAALSRQIDELEET 340
Query: 576 SCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM----KS 631
+ + E + + ++E++ + + K +E++ M +
Sbjct: 341 N--RSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRD 398
Query: 632 LNEKI--TTL--KD--TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQI 685
LN+++ TL KD E+ +L KRI+ ++ N++ +E E++ T KQ
Sbjct: 399 LNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ- 457
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK--QVDFKQKISTLRNRV 743
L + ++ +K K+ EA++ + + + D+ K V F + T+ ++
Sbjct: 458 ------LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKL 511
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELL-NTQKKVQDIVNLEE-------SKKQLQSDC 795
K T+ KL A + +LQ K T E+L+ T++ ++ ++EE + L++
Sbjct: 512 KKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKL 571
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
+ L+ L + +EA + +N+ ++G + A + NK+K L
Sbjct: 572 KAEEEKGNDLLSRVNMLKNRL-QSLEAIEKDFLKNKLNQDSGKSTTA-LHQENNKIKELS 629
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
E+++ K K ++M+ I+ D LM+ + + T + + D + + E K +L
Sbjct: 630 QEVERLKLK--LKDMKAIE---DDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMEL 684
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
K +T W + + E +G E++ + I + G S
Sbjct: 685 AKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHS 744
Query: 976 ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAI 1013
L+K L N + L ++IE +E H +K++
Sbjct: 745 VLQKKLNQQENR-NRDLGREIENLTKELERYRHFSKSL 781
Score = 38.3 bits (85), Expect = 0.16
Identities = 66/335 (19%), Positives = 141/335 (42%), Gaps = 25/335 (7%)
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
+H + + L E+K K KE + +K + I LE+ ++L+
Sbjct: 167 SHRQTILELEEEKRKHKEYM---EKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEK 223
Query: 812 LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREME 871
LKE++ T++ +++ A++ + K++ L ++ K E
Sbjct: 224 RVTTLKEEL---TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEA- 279
Query: 872 KIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD---I 928
++QE K +K++ T + DT+ ++ ++ R L L Q D
Sbjct: 280 RVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEE 339
Query: 929 TN--WQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
TN +K ++EL + I+K E ++ + +L ++ + G EL K + R
Sbjct: 340 TNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIKMEEQCR- 397
Query: 987 ELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINM---II 1043
+L K L ++ + K ++L V K + K I +AL+K F++ K E ++ +
Sbjct: 398 DLNKRLERE---TLQSKDFKLEVEK-LSKRI----MALEKLEDAFNKSKQECYSLKCNLE 449
Query: 1044 RELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDY 1078
+E +++ ++++ + +ES K ++
Sbjct: 450 KERMTTKQLSQELESLKVRIKELEAIESRLEKTEF 484
Score = 35.5 bits (78), Expect = 1.2
Identities = 72/393 (18%), Positives = 166/393 (42%), Gaps = 23/393 (5%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ + I EK + + + E L+K+ K+ E+LK + K+L
Sbjct: 414 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 473
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
++++ + L ++ K +T+ F E + L+ E+
Sbjct: 474 AIESRLEKTEFTLKEDL-TKLKTLTV-MFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 531
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ ++ E+ E TK K + Y VT + KL+ E+ + +N K
Sbjct: 532 V-TTVTEKLIEETKRALKSKTDVEEKMYSVTKER-DDLKNKLKAEEEKGNDLLSRVNMLK 589
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L+ S + +N+ N K+++++++++R K + M
Sbjct: 590 NRLQ--SLEAIEKDFLKNKLNQDSGKSTTALHQEN--NKIKELSQEVERLKLK---LKDM 642
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K++ + + +D E LE+R + + + L++ +E + M L + K+ + +
Sbjct: 643 KAIEDDLMKTED-EYETLERRYANERDKAQFLSKELEHVKMEL--AKYKLAEKTETSHEQ 699
Query: 690 PMLDR-YIQEIKT--VTKKFEAVKEQCGDVDSEMTLDVATAKQVD---FKQKISTLRNRV 743
+ R +E K+ ++++ +A+KE+ + + T D+ Q D ++K++ NR
Sbjct: 700 WLFKRLQEEEAKSGHLSREVDALKEKIHEYMA--TEDLICHLQGDHSVLQKKLNQQENRN 757
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
+ +++ K+L+ Y +K+ LN ++
Sbjct: 758 RDLGREIENLTKELER-YRHFSKSLRPSLNGRR 789
>AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protein 90
protein.
Length = 764
Score = 78.2 bits (184), Expect = 2e-13
Identities = 130/672 (19%), Positives = 281/672 (41%), Gaps = 59/672 (8%)
Query: 424 LQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGN--VPEKDFAVTINKFECE 481
LQ+ + K E+ + +L + KHK + +LG V EK TI + E E
Sbjct: 119 LQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEE 178
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
R LE E + +++ +++ + E + K T ++T
Sbjct: 179 KRKH----KEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELT- 233
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX 601
K + + DEQ L + + + + +L N+ E
Sbjct: 234 -KLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNA------------KETHTKLALAEAR 280
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
K ++ ++LQ + K + ++ K+T +D++ QL++++ + QI L
Sbjct: 281 VQEEEQKATRLEKELQTQTTKFHQ--DQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDEL 337
Query: 662 NETVEEITMS---LIEPEQKMTTAKQ----IHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
ET + + L + ++K++ + I ++ L + + +++ ++ ++EQC
Sbjct: 338 EETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCR 397
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D++ + + +K DFK ++ L R+ +K +A NK Q Y K ++E + T
Sbjct: 398 DLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTT 455
Query: 775 QKKVQDIVNLEESKKQL---QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
++ Q++ +L+ K+L +S + L V ++ + +E +++
Sbjct: 456 KQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTE 515
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREMEKIQEANDKLMEKQK 885
D ++A S ++++V NKV ++ ++ + K+ +V +M + + D L K K
Sbjct: 516 DKLQAAS---SQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Query: 886 QIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGI 945
L +++ LK+ + E ++D N + + T ++++++ E +
Sbjct: 573 AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEV 632
Query: 946 NKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS--LSKDIEKKFREK 1003
+ +L K+ I+ + K E E + + + NE +K+ LSK++E K
Sbjct: 633 ERLKLKLKDMKAIEDDLM---KTE-----DEYETLERRYANERDKAQFLSKELE---HVK 681
Query: 1004 MYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT 1063
M EL K +K + L K L E K +++ + L KI+ + +
Sbjct: 682 M-ELAKYKLAEKTETSHEQWLFKRLQE-EEAKSGHLSREVDALKEKIHEYMATEDLICHL 739
Query: 1064 EGNLTVESERRK 1075
+G+ +V ++ K
Sbjct: 740 QGDHSVLQKKTK 751
Score = 67.7 bits (158), Expect = 2e-10
Identities = 104/543 (19%), Positives = 236/543 (43%), Gaps = 52/543 (9%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+ E+++ ++Y ++ DE I L+++ +L K++I++ +K++E++ K K T
Sbjct: 174 ELEEEKRKHKEYMEKSDEF---ICLLEQECERL--KKLIDQEIKSQEEK-EQEKEKRVTT 227
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L E L + K FA+ + + + ++ + + E
Sbjct: 228 LKEELTKL--KSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEE 285
Query: 519 SELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQN-VLQSSMFIINKYKGQLKDN 575
+ T+ E ++ Q D ++K T +D QN LQ + +++ +L++
Sbjct: 286 QKATRLEKELQTQTTKFHQDQDTIMAKLTN-----EDSQNRQLQQKLAALSRQIDELEET 340
Query: 576 SCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM----KS 631
+ + E + + ++E++ + + K +E++ M +
Sbjct: 341 N--RSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRD 398
Query: 632 LNEKI--TTL--KD--TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQI 685
LN+++ TL KD E+ +L KRI+ ++ N++ +E E++ T KQ
Sbjct: 399 LNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ- 457
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK--QVDFKQKISTLRNRV 743
L + ++ +K K+ EA++ + + + D+ K V F + T+ ++
Sbjct: 458 ------LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKL 511
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELL-NTQKKVQDIVNLEE-------SKKQLQSDC 795
K T+ KL A + +LQ K T E+L+ T++ ++ ++EE + L++
Sbjct: 512 KKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKL 571
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
+ L+ L + +EA + +N+ ++G + A + NK+K L
Sbjct: 572 KAEEEKGNDLLSRVNMLKNRL-QSLEAIEKDFLKNKLNQDSGKSTTA-LHQENNKIKELS 629
Query: 856 AEIQQHK-----KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
E+++ K K + ++ K ++ + L + Q L+K+++ +K E+AK ++
Sbjct: 630 QEVERLKLKLKDMKAIEDDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMELAKYKL 689
Query: 911 YKR 913
++
Sbjct: 690 AEK 692
Score = 36.7 bits (81), Expect = 0.50
Identities = 64/337 (18%), Positives = 140/337 (41%), Gaps = 22/337 (6%)
Query: 750 LNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAI 809
L A + QT+ E + + ++ +K + I LE+ ++L+
Sbjct: 162 LVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEK 221
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPRE 869
LKE++ T++ +++ A++ + K++ L ++ K E
Sbjct: 222 EKRVTTLKEEL---TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAE 278
Query: 870 MEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD-- 927
++QE K +K++ T + DT+ ++ ++ R L L Q D
Sbjct: 279 A-RVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDEL 337
Query: 928 -ITN--WQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
TN +K ++EL + I+K E ++ + +L ++ + G EL K +
Sbjct: 338 EETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIKMEEQC 396
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINM--- 1041
R +L K L ++ + K ++L V K + K I +AL+K F++ K E ++
Sbjct: 397 R-DLNKRLERE---TLQSKDFKLEVEK-LSKRI----MALEKLEDAFNKSKQECYSLKCN 447
Query: 1042 IIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDY 1078
+ +E +++ ++++ + +ES K ++
Sbjct: 448 LEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEF 484
Score = 35.1 bits (77), Expect = 1.5
Identities = 69/370 (18%), Positives = 155/370 (41%), Gaps = 23/370 (6%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ + I EK + + + E L+K+ K+ E+LK + K+L
Sbjct: 414 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 473
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
++++ + L ++ K +T+ F E + L+ E+
Sbjct: 474 AIESRLEKTEFTLKEDL-TKLKTLTV-MFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 531
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ ++ E+ E TK K + Y VT + KL+ E+ + +N K
Sbjct: 532 V-TTVTEKLIEETKRALKSKTDVEEKMYSVTKER-DDLKNKLKAEEEKGNDLLSRVNMLK 589
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L+ S + +N+ N K+++++++++R K + M
Sbjct: 590 NRLQ--SLEAIEKDFLKNKLNQDSGKSTTALHQEN--NKIKELSQEVERLKLK---LKDM 642
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K++ + + +D E LE+R + + + L++ +E + M L + K+ + +
Sbjct: 643 KAIEDDLMKTED-EYETLERRYANERDKAQFLSKELEHVKMEL--AKYKLAEKTETSHEQ 699
Query: 690 PMLDR-YIQEIKT--VTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTT 746
+ R +E K+ ++++ +A+KE+ + + T D+ Q D S L+ + K+T
Sbjct: 700 WLFKRLQEEEAKSGHLSREVDALKEKIHEYMA--TEDLICHLQGDH----SVLQKKTKST 753
Query: 747 QKKLNAHNKK 756
+K+ K+
Sbjct: 754 RKQEQRFRKR 763
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 77.4 bits (182), Expect = 3e-13
Identities = 174/927 (18%), Positives = 374/927 (40%), Gaps = 68/927 (7%)
Query: 204 NLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEK 263
NL L + T ++ + ++L+ S K+ +++E +K + + + K L + + +
Sbjct: 77 NLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAE 136
Query: 264 IDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ +Q+ E A+ EN Q + E + ++ +KS + ++S + E+K
Sbjct: 137 LQSLEQQLEE----AQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQK 192
Query: 324 AQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXX 383
+E T Q+
Sbjct: 193 VTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLK 252
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLK 442
+ + E + I++ + + QE+ Q++ KL+ +L +K + + ENL
Sbjct: 253 DESKKFESQYASSEATISQLRSELSKGPQEVRVYVQELQKLKSSVNELTQKNQTLTENLL 312
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
KE+ L+ KH +V +K+ T+++ + + +
Sbjct: 313 KKEQDYTKLEEKHNEE------SVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVE 366
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
L +E+ + L E SE+ + KA Q K ++ LQ E N L S +
Sbjct: 367 L-SEKGEATQKLKEELSEVETKYQHL-KAEFKQLQQQREEKEQHGLQ-LQSEINQLHSKL 423
Query: 563 FI----INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
+ + G+LK+ + + E + + K+ TE +
Sbjct: 424 LETERQLGEAHGRLKEQRQLS-SEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQ 482
Query: 619 ASAKKDEILSMKSLNEKITT-LKDTE--IPQLEKRIVDVDTQIKTLNETVEEI--TMSLI 673
K + ++L + T L++ + + Q+ ++I + D +I+ L +++ +SL+
Sbjct: 483 LDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLL 542
Query: 674 EPEQKMTTAK--QIHGDMPMLDRYIQEIKT----VTKKFEAVKEQCGDVDSEMTLDVATA 727
E E++ AK G+ +L++ ++ T VT+ E VK Q +S
Sbjct: 543 EKEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQS---ESHKQAQENLH 599
Query: 728 KQV-DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK------KTKAKEELLNTQK--KV 778
QV + K + ++RV + + +N N +L EK + KAK ELL + + K
Sbjct: 600 DQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKT 659
Query: 779 QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGS 838
+L+ Q+ + + L++K E +++ ++ E
Sbjct: 660 AQRADLQNHLDTAQNALQDKHQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYL 719
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHK--KKNVPREMEKIQEANDKL----MEKQKQIMTDRQ 892
+ K E ++K L+A+ + K K+ +++++ ++ N L E KQ+ +++
Sbjct: 720 SLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKE 779
Query: 893 VLTK-KIDTLKD----EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK 947
+++ ++D K E KQ++ K++ + + + +T + Q +ELN ++ +
Sbjct: 780 IVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRI----Q 835
Query: 948 EELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK------DIEKKFR 1001
+ E + + +++ L + + LS++ SLK ++E EK K D+EK +
Sbjct: 836 TTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCK 895
Query: 1002 EKMYELHV-TKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIE 1060
E ++L V + K+ +E +L+K H+ K+E +N + +L + + E
Sbjct: 896 ELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLE-LNSMQEQLIQAQNTLKQNEKEE 954
Query: 1061 IKTEGN---LTVESERRKYDYRVVQSK 1084
+ +GN L SE++K +Q +
Sbjct: 955 QQLQGNINELKQSSEQKKKQIEALQGE 981
Score = 70.5 bits (165), Expect = 3e-11
Identities = 178/946 (18%), Positives = 391/946 (41%), Gaps = 90/946 (9%)
Query: 125 SGKTKDVSSRCADLDI-LMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFD 183
S K D + ADL + L E + + + NS HQ D + + ++ ++
Sbjct: 445 SEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKL 504
Query: 184 ADKYSDCLDRLKKI-RKDYA-QNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIA 240
+ +D L++I KD QNL+ LL+ + +KE ED Y K + E +
Sbjct: 505 REAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVL- 563
Query: 241 NEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTIL 300
N+++ L + Q + +N+ E+ K A+ EN+ + ++A +
Sbjct: 564 -----NQLQEKNHTLQDEVTQLTENVKNQS--ESHKQAQ-ENLHDQVQEQKAH--LRAAQ 613
Query: 301 EKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDI 360
++V SL++ SQ +E ++K + ++ T+
Sbjct: 614 DRVLSLETSVNELNSQLNESKEKVSQLDIQIKA-KTELLLSAEAAKTAQRADLQNHLDTA 672
Query: 361 TSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQK 420
+A Q Q + E + + + + E ++ EQ+ +EL +
Sbjct: 673 QNALQDKHQELNKITTQLDQVTAKLQDKQE-HCSQLESHLKEYKEKYLSLEQKTEELEGQ 731
Query: 421 ITKLQKQTAKLK-EKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFE 479
I KL+ + ++K KE ++L+ +++QL T L + L EK+ V+ + +
Sbjct: 732 IKKLEADSLEVKASKEQALQDLQ-QQRQLNTDLELRATELSKQL--EMEKEI-VSSTRLD 787
Query: 480 CEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDV 539
+ ++E + E K I + E S+ TK + + +
Sbjct: 788 LQKKSEALESIKQKLTK-------QEEEKQILKQDFETLSQETKIQH--------EELNN 832
Query: 540 TLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXX 599
+ T ++K++ E+ L + + + ++ D+ L N E E E
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDS----LKNSKSEFEKENQKGKAAIL 888
Query: 600 XXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIK 659
++ ++ ++ E+ ++ + E+ ++++++ +K
Sbjct: 889 DLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLK 948
Query: 660 TLNETVEEITMSLIE----PEQKMTTAKQIHGDM--PMLDRYIQEIKTVTKKFEAVKEQC 713
+ +++ ++ E EQK + + G++ +L + E K + +A +E
Sbjct: 949 QNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELA 1008
Query: 714 GDVDSEMTLDVATAK-QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
+ + L K Q FKQ S R + +L A + L+++ EK + A+E+L+
Sbjct: 1009 AEKEKISVLQNNYEKSQETFKQLQSDFYGR----ESELLATRQDLKSVEEKLSLAQEDLI 1064
Query: 773 NTQKKVQD----IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+ + ++ + I L+ +K L+ D A+ ++ KEK + E+V
Sbjct: 1065 SNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQ---KEKSLKEKELVN 1121
Query: 829 RNRDLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQI 887
L E I +++ K + L+ E++ HK +++ +E+ +++A L++++ +
Sbjct: 1122 EKSKLAE-----IEEIKCRQEKEITKLNEELKSHKLESI-KEITNLKDAKQLLIQQKLE- 1174
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK 947
L K D+LK + +++ ++ L D ++K + ++ +K+ E KL+
Sbjct: 1175 ------LQGKADSLKAAVEQEKRNQQILKDQ--VKKEEEEL---KKEFIEKEAKLH---- 1219
Query: 948 EELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK--DIEKKFREKMY 1005
E+ EKE + K + +A+ T ++ L ++L + E + S + ++EK+ +
Sbjct: 1220 SEIKEKE---VGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRG 1276
Query: 1006 ELHVTKA-IDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKI 1050
E+ V +A + + E L++CL ++E + + EL RK+
Sbjct: 1277 EIAVLEATVQNNQDERRALLERCLK--GEGEIEKLQTKVLELQRKL 1320
Score = 58.0 bits (134), Expect = 2e-07
Identities = 156/850 (18%), Positives = 350/850 (41%), Gaps = 100/850 (11%)
Query: 193 RLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK 252
RLK+ R+ ++ L E ++ K LE+ K EK+ N S E+++
Sbjct: 436 RLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLK---------EKVTN---STELQHQ- 482
Query: 253 FILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKV 312
L+ Q+ +++ Q TAK+ E +N E + E K ++ +E+L K
Sbjct: 483 ---LDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQK--IQNLEALLQKSKE 537
Query: 313 QKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXX 372
S ++E + + + G T ++ + ++S
Sbjct: 538 NISLLEKEREDLYAKI-QAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQE 596
Query: 373 XXXXXXXXXXXHKQAEN------ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK 426
H +A E ++ E ++NE ++ V Q + ++ ++ + L
Sbjct: 597 NLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELL--LSA 654
Query: 427 QTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFEC-EVRNE 485
+ AK ++ ++ +L T + L++KH+ L ++ + + + + C ++ +
Sbjct: 655 EAAKTAQRADLQNHLDTAQN---ALQDKHQE-LNKITTQLDQVTAKLQDKQEHCSQLESH 710
Query: 486 VXXXXXXXXXXXXXXXXLEAERKHIR-ESLNERRSELTKAED-KIYKACGTQPYDVTLSK 543
+ LE + K + +SL + S+ +D + + T D+ L +
Sbjct: 711 LKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNT---DLEL-R 766
Query: 544 YTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENE---SEXXXXXXXXXX 600
T ++L+ E+ ++ S+ + K K + ++ L + E + +
Sbjct: 767 ATELSKQLEMEKEIVSSTRLDLQK-KSEALESIKQKLTKQEEEKQILKQDFETLSQETKI 825
Query: 601 XXMNVPGKLEKVTEDLQRASAKKDEILS-MKSLNEKITTLKDT---EIPQLEKRIVDVDT 656
+ +++ +LQ+ +K+ +++ + ++ +K++ + D+ + EK
Sbjct: 826 QHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKA 885
Query: 657 QIKTLNETVEEITMSL-IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGD 715
I L +T +E+ L ++ E + K++ + ++K + +++EQ
Sbjct: 886 AILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKL---ELNSMQEQL-- 940
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-----------LYEKK 764
+ ++ TL ++ + I+ L+ + +K++ A +L+ L ++
Sbjct: 941 IQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQL 1000
Query: 765 TKAKEELLNTQKKVQDIVN----LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI 820
T+A +EL ++K+ + N +E+ KQLQSD + +E EK+
Sbjct: 1001 TQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVE----EKL 1056
Query: 821 EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
E + NR+ I + I ++K+ A ++Q K + +++QE L
Sbjct: 1057 SLAQEDLISNRNQIGNQNKLI-------QELKTAKATLEQDSAK----KEQQLQERCKAL 1105
Query: 881 MEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL-N 939
+ QK+ + + K++ K ++A+ E K C + + +IT K ++EL +
Sbjct: 1106 QDIQKE----KSLKEKELVNEKSKLAEIEEIK-------C--RQEKEIT---KLNEELKS 1149
Query: 940 EKLNGINK-EELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
KL I + L + + L+I+Q Q KA+ A E +K + + K ++++K
Sbjct: 1150 HKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKK 1209
Query: 999 KFREKMYELH 1008
+F EK +LH
Sbjct: 1210 EFIEKEAKLH 1219
Score = 44.0 bits (99), Expect = 0.003
Identities = 77/385 (20%), Positives = 157/385 (40%), Gaps = 22/385 (5%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSR----CADLDILMHEELG 147
KQLE+ + + + + K + L+S + + + K + + + + HEEL
Sbjct: 772 KQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELN 831
Query: 148 VSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKL 207
+ + + + + E VK++ ++ D+ K S + K+ +K A L L
Sbjct: 832 NRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKS-EFEKENQKGKAAILDL 890
Query: 208 LENYATTVKAKQKELEDSYKKNTSFNK--EEEKIANEKSSNEIEYNKFILLESQNQEKID 265
+ Q ++E++ K+ K E+EK A+ + E+ + L+++QN K +
Sbjct: 891 EKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN 950
Query: 266 KRNEQIVETAKIAEIENITEVQTN--EEAENATK-TILEKVESLKSDHKVQKSQADEE-- 320
++ EQ ++ I E++ +E + E + K +L+K E L++ + Q +QA +E
Sbjct: 951 EKEEQQLQ-GNINELKQSSEQKKKQIEALQGELKIAVLQKTE-LENKLQQQLTQAAQELA 1008
Query: 321 -EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXX 379
EK+ + + D+ S +
Sbjct: 1009 AEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRN 1068
Query: 380 XXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEE 439
+ EL + E + +K EQ++ E + + +QK+ + LKEKE++ E
Sbjct: 1069 QIGNQNKLIQELKTAKATLEQDSAKK-----EQQLQERCKALQDIQKEKS-LKEKELVNE 1122
Query: 440 NLKTKE-KQLIVLKNKHKTALMELL 463
K E +++ + K T L E L
Sbjct: 1123 KSKLAEIEEIKCRQEKEITKLNEEL 1147
>AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protein
130c protein.
Length = 1133
Score = 77.4 bits (182), Expect = 3e-13
Identities = 113/594 (19%), Positives = 250/594 (42%), Gaps = 54/594 (9%)
Query: 424 LQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGN--VPEKDFAVTINKFECE 481
LQ+ + K E+ + +L + KHK + +LG V EK TI + E E
Sbjct: 119 LQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEE 178
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
R LE E + +++ +++ + E + K T ++T
Sbjct: 179 KRKH----KEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELT- 233
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX 601
K + + DEQ L + + + + +L N+ E
Sbjct: 234 -KLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNA------------KETHTKLALAEAR 280
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
K ++ ++LQ + K + ++ K+T +D++ QL++++ + QI L
Sbjct: 281 VQEEEQKATRLEKELQTQTTKFHQ--DQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDEL 337
Query: 662 NETVEEITMS---LIEPEQKMTTAKQ----IHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
ET + + L + ++K++ + I ++ L + + +++ ++ ++EQC
Sbjct: 338 EETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCR 397
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D++ + + +K DFK ++ L R+ +K +A NK Q Y K ++E + T
Sbjct: 398 DLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTT 455
Query: 775 QKKVQDIVNLEESKKQL---QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
++ Q++ +L+ K+L +S + L V ++ + +E +++
Sbjct: 456 KQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTE 515
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREMEKIQEANDKLMEKQK 885
D ++A S ++++V NKV ++ ++ + K+ +V +M + + D L K K
Sbjct: 516 DKLQAAS---SQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Query: 886 QIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGI 945
L +++ LK+ + E ++D N + + T ++++++ E +
Sbjct: 573 AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEV 632
Query: 946 NKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS--LSKDIE 997
+ +L K+ I+ + K E E + + + NE +K+ LSK++E
Sbjct: 633 ERLKLKLKDMKAIEDDLM---KTE-----DEYETLERRYANERDKAQFLSKELE 678
Score = 70.5 bits (165), Expect = 3e-11
Identities = 124/638 (19%), Positives = 267/638 (41%), Gaps = 53/638 (8%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+ E+++ ++Y ++ DE I L+++ +L K++I++ +K++E++ K K T
Sbjct: 174 ELEEEKRKHKEYMEKSDEF---ICLLEQECERL--KKLIDQEIKSQEEK-EQEKEKRVTT 227
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L E L + K FA+ + + + ++ + + E
Sbjct: 228 LKEELTKL--KSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEE 285
Query: 519 SELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQN-VLQSSMFIINKYKGQLKDN 575
+ T+ E ++ Q D ++K T +D QN LQ + +++ +L++
Sbjct: 286 QKATRLEKELQTQTTKFHQDQDTIMAKLTN-----EDSQNRQLQQKLAALSRQIDELEET 340
Query: 576 SCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM----KS 631
+ + E + + ++E++ + + K +E++ M +
Sbjct: 341 N--RSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRD 398
Query: 632 LNEKI--TTL--KD--TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQI 685
LN+++ TL KD E+ +L KRI+ ++ N++ +E E++ T KQ
Sbjct: 399 LNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ- 457
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK--QVDFKQKISTLRNRV 743
L + ++ +K K+ EA++ + + + D+ K V F + T+ ++
Sbjct: 458 ------LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKL 511
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELL-NTQKKVQDIVNLEE-------SKKQLQSDC 795
K T+ KL A + +LQ K T E+L+ T++ ++ ++EE + L++
Sbjct: 512 KKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKL 571
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
+ L+ L + +EA + +N+ ++G + A + NK+K L
Sbjct: 572 KAEEEKGNDLLSRVNMLKNRL-QSLEAIEKDFLKNKLNQDSGKSTTA-LHQENNKIKELS 629
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
E+++ K K ++M+ I+ D LM+ + + T + + D + + E K +L
Sbjct: 630 QEVERLKLK--LKDMKAIE---DDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMEL 684
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
K +T W + + E +G E++ + I + G S
Sbjct: 685 AKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHS 744
Query: 976 ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAI 1013
L+K L N + L ++IE +E H +K++
Sbjct: 745 VLQKKLNQQENR-NRDLGREIENLTKELERYRHFSKSL 781
Score = 36.7 bits (81), Expect = 0.50
Identities = 64/337 (18%), Positives = 140/337 (41%), Gaps = 22/337 (6%)
Query: 750 LNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAI 809
L A + QT+ E + + ++ +K + I LE+ ++L+
Sbjct: 162 LVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEK 221
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPRE 869
LKE++ T++ +++ A++ + K++ L ++ K E
Sbjct: 222 EKRVTTLKEEL---TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAE 278
Query: 870 MEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD-- 927
++QE K +K++ T + DT+ ++ ++ R L L Q D
Sbjct: 279 A-RVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDEL 337
Query: 928 -ITN--WQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
TN +K ++EL + I+K E ++ + +L ++ + G EL K +
Sbjct: 338 EETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIKMEEQC 396
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINM--- 1041
R +L K L ++ + K ++L V K + K I +AL+K F++ K E ++
Sbjct: 397 R-DLNKRLERE---TLQSKDFKLEVEK-LSKRI----MALEKLEDAFNKSKQECYSLKCN 447
Query: 1042 IIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDY 1078
+ +E +++ ++++ + +ES K ++
Sbjct: 448 LEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEF 484
Score = 35.5 bits (78), Expect = 1.2
Identities = 72/393 (18%), Positives = 166/393 (42%), Gaps = 23/393 (5%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ + I EK + + + E L+K+ K+ E+LK + K+L
Sbjct: 414 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 473
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
++++ + L ++ K +T+ F E + L+ E+
Sbjct: 474 AIESRLEKTEFTLKEDL-TKLKTLTV-MFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 531
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ ++ E+ E TK K + Y VT + KL+ E+ + +N K
Sbjct: 532 V-TTVTEKLIEETKRALKSKTDVEEKMYSVTKER-DDLKNKLKAEEEKGNDLLSRVNMLK 589
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L+ S + +N+ N K+++++++++R K + M
Sbjct: 590 NRLQ--SLEAIEKDFLKNKLNQDSGKSTTALHQEN--NKIKELSQEVERLKLK---LKDM 642
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K++ + + +D E LE+R + + + L++ +E + M L + K+ + +
Sbjct: 643 KAIEDDLMKTED-EYETLERRYANERDKAQFLSKELEHVKMEL--AKYKLAEKTETSHEQ 699
Query: 690 PMLDR-YIQEIKT--VTKKFEAVKEQCGDVDSEMTLDVATAKQVD---FKQKISTLRNRV 743
+ R +E K+ ++++ +A+KE+ + + T D+ Q D ++K++ NR
Sbjct: 700 WLFKRLQEEEAKSGHLSREVDALKEKIHEYMA--TEDLICHLQGDHSVLQKKLNQQENRN 757
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
+ +++ K+L+ Y +K+ LN ++
Sbjct: 758 RDLGREIENLTKELER-YRHFSKSLRPSLNGRR 789
>AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protein
130a protein.
Length = 1135
Score = 77.4 bits (182), Expect = 3e-13
Identities = 113/594 (19%), Positives = 250/594 (42%), Gaps = 54/594 (9%)
Query: 424 LQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGN--VPEKDFAVTINKFECE 481
LQ+ + K E+ + +L + KHK + +LG V EK TI + E E
Sbjct: 119 LQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEE 178
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTL 541
R LE E + +++ +++ + E + K T ++T
Sbjct: 179 KRKH----KEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEKEKRVTTLKEELT- 233
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX 601
K + + DEQ L + + + + +L N+ E
Sbjct: 234 -KLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNA------------KETHTKLALAEAR 280
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
K ++ ++LQ + K + ++ K+T +D++ QL++++ + QI L
Sbjct: 281 VQEEEQKATRLEKELQTQTTKFHQ--DQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDEL 337
Query: 662 NETVEEITMS---LIEPEQKMTTAKQ----IHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
ET + + L + ++K++ + I ++ L + + +++ ++ ++EQC
Sbjct: 338 EETNRSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCR 397
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D++ + + +K DFK ++ L R+ +K +A NK Q Y K ++E + T
Sbjct: 398 DLNKRLERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTT 455
Query: 775 QKKVQDIVNLEESKKQL---QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
++ Q++ +L+ K+L +S + L V ++ + +E +++
Sbjct: 456 KQLSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTE 515
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREMEKIQEANDKLMEKQK 885
D ++A S ++++V NKV ++ ++ + K+ +V +M + + D L K K
Sbjct: 516 DKLQAAS---SQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLK 572
Query: 886 QIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGI 945
L +++ LK+ + E ++D N + + T ++++++ E +
Sbjct: 573 AEEEKGNDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEV 632
Query: 946 NKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS--LSKDIE 997
+ +L K+ I+ + K E E + + + NE +K+ LSK++E
Sbjct: 633 ERLKLKLKDMKAIEDDLM---KTE-----DEYETLERRYANERDKAQFLSKELE 678
Score = 70.5 bits (165), Expect = 3e-11
Identities = 124/638 (19%), Positives = 267/638 (41%), Gaps = 53/638 (8%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+ E+++ ++Y ++ DE I L+++ +L K++I++ +K++E++ K K T
Sbjct: 174 ELEEEKRKHKEYMEKSDEF---ICLLEQECERL--KKLIDQEIKSQEEK-EQEKEKRVTT 227
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L E L + K FA+ + + + ++ + + E
Sbjct: 228 LKEELTKL--KSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEE 285
Query: 519 SELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQN-VLQSSMFIINKYKGQLKDN 575
+ T+ E ++ Q D ++K T +D QN LQ + +++ +L++
Sbjct: 286 QKATRLEKELQTQTTKFHQDQDTIMAKLTN-----EDSQNRQLQQKLAALSRQIDELEET 340
Query: 576 SCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM----KS 631
+ + E + + ++E++ + + K +E++ M +
Sbjct: 341 N--RSLRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRD 398
Query: 632 LNEKI--TTL--KD--TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQI 685
LN+++ TL KD E+ +L KRI+ ++ N++ +E E++ T KQ
Sbjct: 399 LNKRLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQ- 457
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK--QVDFKQKISTLRNRV 743
L + ++ +K K+ EA++ + + + D+ K V F + T+ ++
Sbjct: 458 ------LSQELESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKL 511
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELL-NTQKKVQDIVNLEE-------SKKQLQSDC 795
K T+ KL A + +LQ K T E+L+ T++ ++ ++EE + L++
Sbjct: 512 KKTEDKLQAASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKL 571
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
+ L+ L + +EA + +N+ ++G + A + NK+K L
Sbjct: 572 KAEEEKGNDLLSRVNMLKNRL-QSLEAIEKDFLKNKLNQDSGKSTTA-LHQENNKIKELS 629
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
E+++ K K ++M+ I+ D LM+ + + T + + D + + E K +L
Sbjct: 630 QEVERLKLK--LKDMKAIE---DDLMKTEDEYETLERRYANERDKAQFLSKELEHVKMEL 684
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
K +T W + + E +G E++ + I + G S
Sbjct: 685 AKYKLAEKTETSHEQWLFKRLQEEEAKSGHLSREVDALKEKIHEYMATEDLICHLQGDHS 744
Query: 976 ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAI 1013
L+K L N + L ++IE +E H +K++
Sbjct: 745 VLQKKLNQQENR-NRDLGREIENLTKELERYRHFSKSL 781
Score = 36.7 bits (81), Expect = 0.50
Identities = 64/337 (18%), Positives = 140/337 (41%), Gaps = 22/337 (6%)
Query: 750 LNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAI 809
L A + QT+ E + + ++ +K + I LE+ ++L+
Sbjct: 162 LVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLIDQEIKSQEEKEQEK 221
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPRE 869
LKE++ T++ +++ A++ + K++ L ++ K E
Sbjct: 222 EKRVTTLKEEL---TKLKSFALMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAE 278
Query: 870 MEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD-- 927
++QE K +K++ T + DT+ ++ ++ R L L Q D
Sbjct: 279 A-RVQEEEQKATRLEKELQTQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDEL 337
Query: 928 -ITN--WQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
TN +K ++EL + I+K E ++ + +L ++ + G EL K +
Sbjct: 338 EETNRSLRKAEEELQDIKEKISKGEYG-NAGIMAEVEELRKRVLDMEGKDEELIKMEEQC 396
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINM--- 1041
R +L K L ++ + K ++L V K + K I +AL+K F++ K E ++
Sbjct: 397 R-DLNKRLERE---TLQSKDFKLEVEK-LSKRI----MALEKLEDAFNKSKQECYSLKCN 447
Query: 1042 IIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDY 1078
+ +E +++ ++++ + +ES K ++
Sbjct: 448 LEKERMTTKQLSQELESLKVRIKELEAIESRLEKTEF 484
Score = 35.5 bits (78), Expect = 1.2
Identities = 72/393 (18%), Positives = 166/393 (42%), Gaps = 23/393 (5%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ + I EK + + + E L+K+ K+ E+LK + K+L
Sbjct: 414 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 473
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
++++ + L ++ K +T+ F E + L+ E+
Sbjct: 474 AIESRLEKTEFTLKEDL-TKLKTLTV-MFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 531
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ ++ E+ E TK K + Y VT + KL+ E+ + +N K
Sbjct: 532 V-TTVTEKLIEETKRALKSKTDVEEKMYSVTKER-DDLKNKLKAEEEKGNDLLSRVNMLK 589
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L+ S + +N+ N K+++++++++R K + M
Sbjct: 590 NRLQ--SLEAIEKDFLKNKLNQDSGKSTTALHQEN--NKIKELSQEVERLKLK---LKDM 642
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K++ + + +D E LE+R + + + L++ +E + M L + K+ + +
Sbjct: 643 KAIEDDLMKTED-EYETLERRYANERDKAQFLSKELEHVKMEL--AKYKLAEKTETSHEQ 699
Query: 690 PMLDR-YIQEIKT--VTKKFEAVKEQCGDVDSEMTLDVATAKQVD---FKQKISTLRNRV 743
+ R +E K+ ++++ +A+KE+ + + T D+ Q D ++K++ NR
Sbjct: 700 WLFKRLQEEEAKSGHLSREVDALKEKIHEYMA--TEDLICHLQGDHSVLQKKLNQQENRN 757
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
+ +++ K+L+ Y +K+ LN ++
Sbjct: 758 RDLGREIENLTKELER-YRHFSKSLRPSLNGRR 789
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 77.0 bits (181), Expect = 4e-13
Identities = 121/643 (18%), Positives = 273/643 (42%), Gaps = 47/643 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQK-ITKLQKQTAK-LKEKEMIEENLKTKE 445
++EL I+ ++ + + + E + EL+++ +L + + KE ++ + L+ E
Sbjct: 233 QDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME 292
Query: 446 KQLIVLK---NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
++ K N ++ +LL + K + + + E +
Sbjct: 293 LRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQ 352
Query: 503 LEAERKHIRESLNER-RSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSS 561
E E +RE ++ R + A+ K + + D +S + L++E +L+S+
Sbjct: 353 KEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSMERGLRDLEEEIQMLKSN 411
Query: 562 MFIINKYKGQ-LKDNSCCPLCNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
+ + + + +K ++ +N+ + + + KLE +T +
Sbjct: 412 GALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDS 471
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ + + E+ + TE+ L R+ + +T + + ++++ E+K
Sbjct: 472 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA------EEKG 525
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T A +IH MLD +++ + KK E ++EQ D + +M+ + ++V Q +T
Sbjct: 526 TQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS---SLKERVKSLQADTTN 582
Query: 740 RNRVKTT-QKKLNAHNKKLQTLYEKKTK----AKEELLNTQKKVQDI---VNL------- 784
+ TT ++ L + ++ L E++ + +EE+ N +K ++D+ V+L
Sbjct: 583 TDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 642
Query: 785 -EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
E S L+ + LE+AL++K E ++ + + EA A
Sbjct: 643 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARAS 702
Query: 844 VEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD 903
E++ ++++ L+ EI ++K E K Q D+L+E K++ ++ KKI L+
Sbjct: 703 PEMS-DRIQHLEREITRYKD-----ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELES 756
Query: 904 EIAKQ------EVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
++Q +V + + +K+ + ++++D LN+ + EEL +
Sbjct: 757 LTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQVEELLMAMEKV 816
Query: 958 IKQTKLFQQKAECT-GALSELKKSLKGFRNELEKSLSKDIEKK 999
++ + + K T +L+E + L R E K L + +E K
Sbjct: 817 KQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMK 859
Score = 37.1 bits (82), Expect = 0.38
Identities = 83/534 (15%), Positives = 209/534 (39%), Gaps = 44/534 (8%)
Query: 258 SQNQEKIDKRNEQIVETAKIAEIENITEVQTNE--EAENATKTILEKVESLKSDHKVQKS 315
S +E++ +R E ++AK ++ + E++ ++ E + + E+++ LKS+ +
Sbjct: 358 SMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLKSNGALSTE 417
Query: 316 QADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQ-SXXXXXXXX 374
+ +EE K+ + + + + T NQ S
Sbjct: 418 EREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEV 477
Query: 375 XXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK 434
+ A + ++ + + E E + + +++ ++++ +K T + E
Sbjct: 478 LKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAE-----EKGT-QAGEI 531
Query: 435 EMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXX 494
+++ L KE+++ VL+ K + L E L +D ++ + V++
Sbjct: 532 HDLKDMLDVKERKVNVLQKKIEN-LQEQL-----RDKEKQMSSLKERVKSLQADTTNTDT 585
Query: 495 XXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE 554
L AE++ E L E+R + + + + Y ++ L+++
Sbjct: 586 ALTTLEEAL-AEKERTIERLKEQRDRDEREKQE------------EIDNYKKDLKDLKEK 632
Query: 555 QNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXX---MNVPGKLEK 611
++LQ + LK+++ L + G + +S + + +L+K
Sbjct: 633 VSLLQGDLSEKEASLLDLKEHASS-LASSGLKKDSRLKTLEIALEQKKEECLKMESQLKK 691
Query: 612 VTEDLQRASAKKDEILSMKSLNEKITTLKD------TEIPQLEKRIVDVDTQIKTLNETV 665
E A A + ++ L +IT KD E+ +L + + +V+ + ++ +
Sbjct: 692 AHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKI 751
Query: 666 EEITM--SLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
E+ S +Q A H + + Q ++ ++ ++ D ++ ++
Sbjct: 752 AELESLTSRQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRR----EDNLNDSSQQLQVE 807
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
KQ++ +++ ++ +TQ+ L L L ++ K EE+L +++
Sbjct: 808 ELLMAMEKVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQE 861
>BC027860-1|AAH27860.1| 893|Homo sapiens filamin A interacting
protein 1-like protein.
Length = 893
Score = 75.8 bits (178), Expect = 9e-13
Identities = 80/408 (19%), Positives = 189/408 (46%), Gaps = 34/408 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
K ++ ++LQ + K + ++ K+T +D++ QL++++ + QI L ET
Sbjct: 47 KATRLEKELQTQTTKFHQ--DQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDELEETNRS 103
Query: 668 ITMS---LIEPEQKMTTAKQ----IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM 720
+ + L + ++K++ + I ++ L + + +++ ++ ++EQC D++ +
Sbjct: 104 LRKAEEELQDIKEKISKGEYGNAGIMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRL 163
Query: 721 TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD 780
+ +K DFK ++ L R+ +K +A NK Q Y K ++E + T++ Q+
Sbjct: 164 ERETLQSK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQE 221
Query: 781 IVNLEESKKQL---QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG 837
+ +L+ K+L +S + L V ++ + +E +++ D ++A
Sbjct: 222 LESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAA 281
Query: 838 SAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREMEKIQEANDKLMEKQKQIMTDR 891
S ++++V NKV ++ ++ + K+ +V +M + + D L K K
Sbjct: 282 S---SQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKG 338
Query: 892 QVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELN 951
L +++ LK+ + E ++D N + + T ++++++ E + + +L
Sbjct: 339 NDLLSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLK 398
Query: 952 EKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS--LSKDIE 997
K+ I+ + K E E + + + NE +K+ LSK++E
Sbjct: 399 LKDMKAIEDDLM---KTE-----DEYETLERRYANERDKAQFLSKELE 438
Score = 35.9 bits (79), Expect = 0.88
Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 19/245 (7%)
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
A++ + K++ L ++ K E ++QE K +K++ T + DT+
Sbjct: 11 AQLTLQRQKIQELTTNAKETHTKLALAEA-RVQEEEQKATRLEKELQTQTTKFHQDQDTI 69
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTD---ITN--WQKQDDELNEKLNGINKEELNEKESL 956
++ ++ R L L Q D TN +K ++EL + I+K E +
Sbjct: 70 MAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGI 128
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
+ + +L ++ + G EL K + R +L K L ++ + K ++L V K + K
Sbjct: 129 MAEVEELRKRVLDMEGKDEELIKMEEQCR-DLNKRLERE---TLQSKDFKLEVEK-LSKR 183
Query: 1017 IREYAVALDKCLMEFHREKMENINM---IIRELWRKIYRGNDIDYIEIKTEGNLTVESER 1073
I +AL+K F++ K E ++ + +E +++ ++++ + +ES
Sbjct: 184 I----MALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELEAIESRL 239
Query: 1074 RKYDY 1078
K ++
Sbjct: 240 EKTEF 244
Score = 35.5 bits (78), Expect = 1.2
Identities = 72/393 (18%), Positives = 166/393 (42%), Gaps = 23/393 (5%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ + I EK + + + E L+K+ K+ E+LK + K+L
Sbjct: 174 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 233
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
++++ + L ++ K +T+ F E + L+ E+
Sbjct: 234 AIESRLEKTEFTLKEDL-TKLKTLTV-MFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 291
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ ++ E+ E TK K + Y VT + KL+ E+ + +N K
Sbjct: 292 V-TTVTEKLIEETKRALKSKTDVEEKMYSVTKER-DDLKNKLKAEEEKGNDLLSRVNMLK 349
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L+ S + +N+ N K+++++++++R K + M
Sbjct: 350 NRLQ--SLEAIEKDFLKNKLNQDSGKSTTALHQEN--NKIKELSQEVERLKLK---LKDM 402
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K++ + + +D E LE+R + + + L++ +E + M L + K+ + +
Sbjct: 403 KAIEDDLMKTED-EYETLERRYANERDKAQFLSKELEHVKMEL--AKYKLAEKTETSHEQ 459
Query: 690 PMLDR-YIQEIKT--VTKKFEAVKEQCGDVDSEMTLDVATAKQVD---FKQKISTLRNRV 743
+ R +E K+ ++++ +A+KE+ + + T D+ Q D ++K++ NR
Sbjct: 460 WLFKRLQEEEAKSGHLSREVDALKEKIHEYMA--TEDLICHLQGDHSVLQKKLNQQENRN 517
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
+ +++ K+L+ Y +K+ LN ++
Sbjct: 518 RDLGREIENLTKELER-YRHFSKSLRPSLNGRR 549
>M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein.
Length = 2871
Score = 75.4 bits (177), Expect = 1e-12
Identities = 175/949 (18%), Positives = 384/949 (40%), Gaps = 88/949 (9%)
Query: 105 LAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHE-ELGVSKAILNSVVFCHQED 163
L K TK + L+ L ++ ++ D ++ ++ E KA L S+ ++
Sbjct: 1027 LKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQA 1086
Query: 164 SSWPLDEGKKVKERFDEIFDADK-YSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKEL 222
LD GK K+ D+ + K ++ + RL +D + K +E+ K +L
Sbjct: 1087 E---LD-GKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQL 1142
Query: 223 EDSY---KKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAE 279
+ + K+N + K E + A ++ EIE + +LL+ + K + NE +A+
Sbjct: 1143 QKARQCEKENLGWQKLESEKAIKEKEYEIERLR-VLLQEEGTRKREYENE-------LAK 1194
Query: 280 IENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXX 339
+ N NEE N ++ K+ K Q +++ K + +D +
Sbjct: 1195 VRN----HYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLK 1250
Query: 340 XXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQE 399
+A Q K+ E+ +++ Q+
Sbjct: 1251 DEIVRLNDSILQATEQRRRAEENALQQKACGSEIM---------QKKQHLEIELKQVMQQ 1301
Query: 400 INEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTK-EKQLIVLKNKHKTA 458
+ED +++Q ++E ++ I K+ +LK + E + + E +L ++N +
Sbjct: 1302 RSEDNA---RHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEE 1358
Query: 459 LMELLGNVPEKDFAVT---INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLN 515
++ L N E + +T I++ + + L E K ++ +L
Sbjct: 1359 IISLK-NQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLT 1417
Query: 516 ERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN 575
+ L + E+ I + T +V+ K VE Q Q + S+ +YK L D
Sbjct: 1418 QTTENLRRVEEDIQQQKATGS-EVSQRKQQLEVELRQVTQMRTEESV----RYKQSLDDA 1472
Query: 576 S-CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS-MKSLN 633
+ N+ E + + +L++V DLQ+A++ E ++ +K
Sbjct: 1473 AKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQE 1532
Query: 634 EKITTLK-DTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG-DMPM 691
+++T L+ D E E+ + D D I +++E+ + + E+++ K+ D
Sbjct: 1533 QELTRLRIDYERVSQERTVKDQD--ITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCK 1590
Query: 692 LDRYIQEIKTVTK--KFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT---T 746
+ +E++ + + K +A+K E V + D +Q+ L ++ T
Sbjct: 1591 RKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRT 1650
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXX 806
Q++L + +++ L + + +E + + + E K + ++
Sbjct: 1651 QEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLT 1710
Query: 807 XAITPLEVALKEKIE---AKTEVVRRNRDLIEAG-SAYI----AKVEVAFNKVKSLDAEI 858
+T + L+E++ + + +RR R ++ +A I ++++++ N+ L I
Sbjct: 1711 ENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLI 1770
Query: 859 Q--QHKKKNVPREMEKIQ----EANDKLMEKQKQ---IMTDRQVLTKKIDTLKDEIAKQE 909
Q +++N+ +E+EK Q EA++++ E + Q ++ +R+ L KI L+ + A+ +
Sbjct: 1771 NDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQ 1830
Query: 910 VYKRDLDDNLCLRKAQT---------------DITNWQKQDDELNEKLNGINKE-ELNEK 953
+ +L+ +A+T D+ W+ Q E + I E E +E+
Sbjct: 1831 RLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSER 1890
Query: 954 ESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
E ++ +++ + +AE ++ L+ E + L + + RE
Sbjct: 1891 EKNSLR-SEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQRE 1938
Score = 48.8 bits (111), Expect = 1e-04
Identities = 134/754 (17%), Positives = 292/754 (38%), Gaps = 75/754 (9%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE 242
D+ + LDRL + +D + L + +++ E++ + + E I +
Sbjct: 1231 DSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSE---IMQK 1287
Query: 243 KSSNEIEYNKFILLESQNQEKIDKRNEQIVETA--KIAEIENIT-----EVQTNEEAENA 295
K EIE + + S++ + + E+ +T K EIE + E + E EN
Sbjct: 1288 KQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENE 1347
Query: 296 TKTIL----EKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXX 351
+ E++ SLK+ + + + + +E SG+
Sbjct: 1348 LSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSE 1407
Query: 352 XXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYE 411
+T ++ Q + +L +E Q E++V +Y+
Sbjct: 1408 EIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESV-RYK 1466
Query: 412 QEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDF 471
Q +D+ ++ I K+ +LK+ +I++ +T +++ + +N + L
Sbjct: 1467 QSLDDAAKTIQDKNKEIERLKQ--LIDK--ETNDRKCLEDENARLQRVQYDLQKA-NSSA 1521
Query: 472 AVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKA 531
TINK + + E+ + + + SL E + + K E+++ +
Sbjct: 1522 TETINKLKVQ-EQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRL 1580
Query: 532 CGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEX 591
T D K E+L+ + L+ I QL+ S + + E++
Sbjct: 1581 KRTASEDSCKRKKLE--EELEGMRRSLKEQAIKITNLTQQLEQAS---IVKKRSEDDLRQ 1635
Query: 592 XXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRI 651
+ ++ E+L+R S++ E L + L E+ ++K + E
Sbjct: 1636 QRDVLDGHLR------EKQRTQEELRRLSSEV-EALRRQLLQEQ-ESVKQAHLRN-EHFQ 1686
Query: 652 VDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
++ + ++LNE S IE E+ + + + + ML+ +E++ + +++ ++
Sbjct: 1687 KAIEDKSRSLNE-------SKIEIERLQSLTENLTKEHLMLE---EELRNLRLEYDDLRR 1736
Query: 712 QCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL 771
+ DS+ + ++ + ++ NR Q +N ++ + L ++ K +++
Sbjct: 1737 GRSEADSDKNATI-----LELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQA 1791
Query: 772 LNTQKKVQD-------IVNLEESK----KQLQSDCXXXXXXXXXXXXAITPLEVALKEKI 820
L ++Q+ +V ES K L+ D A + LE + K
Sbjct: 1792 LEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQ 1851
Query: 821 EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQ------ 874
+ E + DL + + Y K E A K++S + E + +K ++ E+E++Q
Sbjct: 1852 RLECEKQQIQNDLNQWKTQYSRKEE-AIRKIES-EREKSEREKNSLRSEIERLQAEIKRI 1909
Query: 875 ------EANDKLMEKQKQIMTDRQVLTKKIDTLK 902
+ D E Q Q+ T+R ++ID L+
Sbjct: 1910 EERCRRKLEDSTRETQSQLETERSRYQREIDKLR 1943
Score = 41.1 bits (92), Expect = 0.023
Identities = 47/194 (24%), Positives = 89/194 (45%), Gaps = 13/194 (6%)
Query: 851 VKSL-DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQE 909
+KSL D +++ K + + E+ ++AN + K K + + Q + K ++A E
Sbjct: 1021 LKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLE 1080
Query: 910 VYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
KR + L + A+ ++ Q ELNEK+ + E +EK + + QQK +
Sbjct: 1081 ELKRQAE--LDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKND 1138
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD----IREYAVALD 1025
+L+K+ + + L + EK +EK YE+ + + ++ REY L
Sbjct: 1139 ----YDQLQKARQCEKENLGWQ-KLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELA 1193
Query: 1026 KCLMEFHREKMENI 1039
K + + E+M N+
Sbjct: 1194 K-VRNHYNEEMSNL 1206
Score = 34.3 bits (75), Expect = 2.7
Identities = 34/144 (23%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Query: 191 LDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFN--KEEEKIANEKSSNEI 248
L + Y + L +Y + K LED KNT +EE ++A + +S
Sbjct: 993 LQEAADVHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENC 1052
Query: 249 EYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKS 308
NKF+ QN +K Q AK+A +E + Q + ++A + + + +K
Sbjct: 1053 NKNKFL---DQNLQKYQAECSQF--KAKLASLEELKR-QAELDGKSAKQNLDKCYGQIKE 1106
Query: 309 -DHKVQKSQAD-EEEKKAQGFVDE 330
+ K+ + + E+EK+ + V++
Sbjct: 1107 LNEKITRLTYEIEDEKRRRKSVED 1130
>AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein.
Length = 2871
Score = 75.4 bits (177), Expect = 1e-12
Identities = 175/949 (18%), Positives = 384/949 (40%), Gaps = 88/949 (9%)
Query: 105 LAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHE-ELGVSKAILNSVVFCHQED 163
L K TK + L+ L ++ ++ D ++ ++ E KA L S+ ++
Sbjct: 1027 LKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQA 1086
Query: 164 SSWPLDEGKKVKERFDEIFDADK-YSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKEL 222
LD GK K+ D+ + K ++ + RL +D + K +E+ K +L
Sbjct: 1087 E---LD-GKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQL 1142
Query: 223 EDSY---KKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAE 279
+ + K+N + K E + A ++ EIE + +LL+ + K + NE +A+
Sbjct: 1143 QKARQCEKENLGWQKLESEKAIKEKEYEIERLR-VLLQEEGTRKREYENE-------LAK 1194
Query: 280 IENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXX 339
+ N NEE N ++ K+ K Q +++ K + +D +
Sbjct: 1195 VRN----HYNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLK 1250
Query: 340 XXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQE 399
+A Q K+ E+ +++ Q+
Sbjct: 1251 DEIVRLNDSILQATEQRRRAEENALQQKACGSEIM---------QKKQHLEIELKQVMQQ 1301
Query: 400 INEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTK-EKQLIVLKNKHKTA 458
+ED +++Q ++E ++ I K+ +LK + E + + E +L ++N +
Sbjct: 1302 RSEDNA---RHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEE 1358
Query: 459 LMELLGNVPEKDFAVT---INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLN 515
++ L N E + +T I++ + + L E K ++ +L
Sbjct: 1359 IISLK-NQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLT 1417
Query: 516 ERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN 575
+ L + E+ I + T +V+ K VE Q Q + S+ +YK L D
Sbjct: 1418 QTTENLRRVEEDIQQQKATGS-EVSQRKQQLEVELRQVTQMRTEESV----RYKQSLDDA 1472
Query: 576 S-CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS-MKSLN 633
+ N+ E + + +L++V DLQ+A++ E ++ +K
Sbjct: 1473 AKTIQDKNKEIERLKQLIDKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQE 1532
Query: 634 EKITTLK-DTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG-DMPM 691
+++T L+ D E E+ + D D I +++E+ + + E+++ K+ D
Sbjct: 1533 QELTRLRIDYERVSQERTVKDQD--ITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCK 1590
Query: 692 LDRYIQEIKTVTK--KFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT---T 746
+ +E++ + + K +A+K E V + D +Q+ L ++ T
Sbjct: 1591 RKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQRDVLDGHLREKQRT 1650
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXX 806
Q++L + +++ L + + +E + + + E K + ++
Sbjct: 1651 QEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLT 1710
Query: 807 XAITPLEVALKEKIE---AKTEVVRRNRDLIEAG-SAYI----AKVEVAFNKVKSLDAEI 858
+T + L+E++ + + +RR R ++ +A I ++++++ N+ L I
Sbjct: 1711 ENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLI 1770
Query: 859 Q--QHKKKNVPREMEKIQ----EANDKLMEKQKQ---IMTDRQVLTKKIDTLKDEIAKQE 909
Q +++N+ +E+EK Q EA++++ E + Q ++ +R+ L KI L+ + A+ +
Sbjct: 1771 NDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQ 1830
Query: 910 VYKRDLDDNLCLRKAQT---------------DITNWQKQDDELNEKLNGINKE-ELNEK 953
+ +L+ +A+T D+ W+ Q E + I E E +E+
Sbjct: 1831 RLEDELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSER 1890
Query: 954 ESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
E ++ +++ + +AE ++ L+ E + L + + RE
Sbjct: 1891 EKNSLR-SEIERLQAEIKRIEERCRRKLEDSTRETQSQLETERSRYQRE 1938
Score = 48.8 bits (111), Expect = 1e-04
Identities = 134/754 (17%), Positives = 292/754 (38%), Gaps = 75/754 (9%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE 242
D+ + LDRL + +D + L + +++ E++ + + E I +
Sbjct: 1231 DSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSE---IMQK 1287
Query: 243 KSSNEIEYNKFILLESQNQEKIDKRNEQIVETA--KIAEIENIT-----EVQTNEEAENA 295
K EIE + + S++ + + E+ +T K EIE + E + E EN
Sbjct: 1288 KQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENE 1347
Query: 296 TKTIL----EKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXX 351
+ E++ SLK+ + + + + +E SG+
Sbjct: 1348 LSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSE 1407
Query: 352 XXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYE 411
+T ++ Q + +L +E Q E++V +Y+
Sbjct: 1408 EIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESV-RYK 1466
Query: 412 QEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDF 471
Q +D+ ++ I K+ +LK+ +I++ +T +++ + +N + L
Sbjct: 1467 QSLDDAAKTIQDKNKEIERLKQ--LIDK--ETNDRKCLEDENARLQRVQYDLQKA-NSSA 1521
Query: 472 AVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKA 531
TINK + + E+ + + + SL E + + K E+++ +
Sbjct: 1522 TETINKLKVQ-EQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRL 1580
Query: 532 CGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEX 591
T D K E+L+ + L+ I QL+ S + + E++
Sbjct: 1581 KRTASEDSCKRKKLE--EELEGMRRSLKEQAIKITNLTQQLEQAS---IVKKRSEDDLRQ 1635
Query: 592 XXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRI 651
+ ++ E+L+R S++ E L + L E+ ++K + E
Sbjct: 1636 QRDVLDGHLR------EKQRTQEELRRLSSEV-EALRRQLLQEQ-ESVKQAHLRN-EHFQ 1686
Query: 652 VDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
++ + ++LNE S IE E+ + + + + ML+ +E++ + +++ ++
Sbjct: 1687 KAIEDKSRSLNE-------SKIEIERLQSLTENLTKEHLMLE---EELRNLRLEYDDLRR 1736
Query: 712 QCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL 771
+ DS+ + ++ + ++ NR Q +N ++ + L ++ K +++
Sbjct: 1737 GRSEADSDKNATI-----LELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQA 1791
Query: 772 LNTQKKVQD-------IVNLEESK----KQLQSDCXXXXXXXXXXXXAITPLEVALKEKI 820
L ++Q+ +V ES K L+ D A + LE + K
Sbjct: 1792 LEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQ 1851
Query: 821 EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQ------ 874
+ E + DL + + Y K E A K++S + E + +K ++ E+E++Q
Sbjct: 1852 RLECEKQQIQNDLNQWKTQYSRKEE-AIRKIES-EREKSEREKNSLRSEIERLQAEIKRI 1909
Query: 875 ------EANDKLMEKQKQIMTDRQVLTKKIDTLK 902
+ D E Q Q+ T+R ++ID L+
Sbjct: 1910 EERCRRKLEDSTRETQSQLETERSRYQREIDKLR 1943
Score = 41.1 bits (92), Expect = 0.023
Identities = 47/194 (24%), Positives = 89/194 (45%), Gaps = 13/194 (6%)
Query: 851 VKSL-DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQE 909
+KSL D +++ K + + E+ ++AN + K K + + Q + K ++A E
Sbjct: 1021 LKSLEDLKLKNTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLE 1080
Query: 910 VYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
KR + L + A+ ++ Q ELNEK+ + E +EK + + QQK +
Sbjct: 1081 ELKRQAE--LDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKND 1138
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD----IREYAVALD 1025
+L+K+ + + L + EK +EK YE+ + + ++ REY L
Sbjct: 1139 ----YDQLQKARQCEKENLGWQ-KLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELA 1193
Query: 1026 KCLMEFHREKMENI 1039
K + + E+M N+
Sbjct: 1194 K-VRNHYNEEMSNL 1206
Score = 34.3 bits (75), Expect = 2.7
Identities = 34/144 (23%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Query: 191 LDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFN--KEEEKIANEKSSNEI 248
L + Y + L +Y + K LED KNT +EE ++A + +S
Sbjct: 993 LQEAADVHARYIELLTRSGDYYRFLSEMLKSLEDLKLKNTKIEVLEEELRLARDANSENC 1052
Query: 249 EYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKS 308
NKF+ QN +K Q AK+A +E + Q + ++A + + + +K
Sbjct: 1053 NKNKFL---DQNLQKYQAECSQF--KAKLASLEELKR-QAELDGKSAKQNLDKCYGQIKE 1106
Query: 309 -DHKVQKSQAD-EEEKKAQGFVDE 330
+ K+ + + E+EK+ + V++
Sbjct: 1107 LNEKITRLTYEIEDEKRRRKSVED 1130
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 75.4 bits (177), Expect = 1e-12
Identities = 120/682 (17%), Positives = 287/682 (42%), Gaps = 44/682 (6%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQK-ITKLQKQTAK-LKEKEMIEENLKTKE 445
++EL I+ ++ + + + E + EL+++ +L + + KE ++ + L+ E
Sbjct: 233 QDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME 292
Query: 446 KQLIVLK---NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
++ K N ++ +LL + K + + + E +
Sbjct: 293 LRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQ 352
Query: 503 LEAERKHIRESLNER-RSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSS 561
E E +RE ++ R + A+ K + + D +S + L++E +L+S+
Sbjct: 353 KEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSMERGLRDLEEEIQMLKSN 411
Query: 562 MFIINKYKGQ-LKDNSCCPLCNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
+ + + + +K ++ +N+ + + + KLE +T +
Sbjct: 412 GALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDS 471
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ + + E+ + TE+ L R+ + +T + + ++++ E+K
Sbjct: 472 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA------EEKG 525
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T A +IH MLD +++ + KK E ++EQ D + +M+ + ++V Q +T
Sbjct: 526 TQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS---SLKERVKSLQADTTN 582
Query: 740 RNRVKTT-QKKLNAHNKKLQTLYEKKTK----AKEELLNTQKKVQDI---VNL------- 784
+ TT ++ L + ++ L E++ + +EE+ N +K ++D+ V+L
Sbjct: 583 TDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 642
Query: 785 -EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
E S L+ + LE+AL++K E ++ + + EA A
Sbjct: 643 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARAS 702
Query: 844 VEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD 903
E++ ++++ L+ EI ++K E K Q D+L+E K++ ++ KKI L+
Sbjct: 703 PEMS-DRIQHLEREITRYKD-----ESSKAQAEVDRLLEILKEVENEKNDKDKKIAELER 756
Query: 904 EIAKQEVYKRDL--DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
++ Q +L + + +K+ + ++++D LN+ + ++ L +K+ I +
Sbjct: 757 QVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL-QDSLRKKDDRIEELE 815
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ ++ + T + + R EK + +++ + EL KA ++
Sbjct: 816 EALRESVQITAEREMVLAQEESARTNAEKQV-EELLMAMEKVKQELESMKAKLSSTQQSL 874
Query: 1022 VALDKCLMEFHREKMENINMII 1043
+ L E+ +++ ++
Sbjct: 875 AEKETHLTNLRAERRKHLEEVL 896
Score = 62.1 bits (144), Expect = 1e-08
Identities = 116/631 (18%), Positives = 252/631 (39%), Gaps = 29/631 (4%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDE--LSQKITKLQ-KQTAKLKEKEM----IEEN 440
E EL IE +Q +N ++++++ + + LS K T+ ++T +L E EM +E
Sbjct: 290 EMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESL 349
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXX 500
L+ KEK+ +L+ + + K I + ++ +
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLK 409
Query: 501 XXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQS 560
+ E + ++ E+ ++ K K Q LS+ T + LQ + L +
Sbjct: 410 SNGALSTEEREEEM--KQMEVYRSHSKFMKNKIGQVKQ-ELSRKDTELLALQTKLETLTN 466
Query: 561 SMFIINKYKGQLKDNSCCPLCNRGF-ENESEXXXXXXXXXXXXMNVPGK-LEKVTEDLQR 618
++ LK++ + E + +N K ++ + E+
Sbjct: 467 QFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGT 526
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
+ + ++ M + E+ + +I L++++ D + Q+ +L E V+ + +
Sbjct: 527 QAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTA 586
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGD---VDSEMTLDVATAKQVDFKQK 735
+TT ++ + +R I+ +K + E K++ D D + + + Q D +K
Sbjct: 587 LTTLEEALAEK---ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEK 643
Query: 736 ISTLRNRVKTTQKKLNAHNKK---LQTLYEKKTKAKEELLNTQ---KKVQDIVNLEESKK 789
++L + + ++ KK L+TL + KEE L + KK + +
Sbjct: 644 EASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASP 703
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
++ + + + +E EV D + + +V+
Sbjct: 704 EMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNK 763
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD-EIAKQ 908
KV +L + Q KKK+ + +E+ + D L + +Q+ L KK D +++ E A +
Sbjct: 764 KVANLKHKEQVEKKKSA-QMLEEARRREDNLNDSSQQLQDS---LRKKDDRIEELEEALR 819
Query: 909 EVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKA 968
E + + + L + ++ TN +KQ +EL + + +E + K L Q L +++
Sbjct: 820 ESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKET 879
Query: 969 ECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
T +E +K L+ +++L I +K
Sbjct: 880 HLTNLRAERRKHLEEVLEMKQEALLAAISEK 910
>U53445-1|AAA98972.1| 752|Homo sapiens DOC1 protein.
Length = 752
Score = 74.5 bits (175), Expect = 2e-12
Identities = 82/402 (20%), Positives = 185/402 (46%), Gaps = 36/402 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
K ++ ++LQ + K + ++ K+T +D++ QL++++ + QI L ET
Sbjct: 47 KATRLEKELQTQTTKFHQ--DQDTIMAKLTN-EDSQNRQLQQKLAALSRQIDELEETNRS 103
Query: 668 ITMSLIEPEQ-KMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ + E + K +K +G+ ++ E++ + K ++EQC D++ + +
Sbjct: 104 LRKAEEELQDIKEKISKGEYGNAGIM----AEVEELIK----MEEQCRDLNKRLERETLQ 155
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
+K DFK ++ L R+ +K +A NK Q Y K ++E + T++ Q++ +L+
Sbjct: 156 SK--DFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKV 213
Query: 787 SKKQL---QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
K+L +S + L V ++ + +E +++ D ++A S ++
Sbjct: 214 RIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAAS---SQ 270
Query: 844 VEVAFNKVKSLDAEIQQHKKK------NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
++V NKV ++ ++ + K+ +V +M + + D L K K L +
Sbjct: 271 LQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDLLSR 330
Query: 898 IDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
++ LK+ + E ++D N + + T ++++++ E + + +L K+
Sbjct: 331 VNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKDMKA 390
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKS--LSKDIE 997
I+ + K E E + + + NE +K+ LSK++E
Sbjct: 391 IEDDLM---KTE-----DEYETLERRYANERDKAQFLSKELE 424
Score = 36.7 bits (81), Expect = 0.50
Identities = 73/393 (18%), Positives = 166/393 (42%), Gaps = 23/393 (5%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ + I EK + + + E L+K+ K+ E+LK + K+L
Sbjct: 160 KLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELESLKVRIKELE 219
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
++++ + L ++ K +T+ F E + L+ E+
Sbjct: 220 AIESRLEKTEFTLKEDL-TKLKTLTV-MFVDERKTMSEKLKKTEDKLQAASSQLQVEQNK 277
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ ++ E+ E TK K + Y VT + KL+ E+ + +N K
Sbjct: 278 V-TTVTEKLIEETKRALKSKTDVEEKMYSVTKER-DDLKNKLKAEEEKGNDLLSRVNMLK 335
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L+ S + +N+ N K+++++++++R K + M
Sbjct: 336 NRLQ--SLEAIEKDFLKNKLNQDSGKSTTALHQEN--NKIKELSQEVERLKLK---LKDM 388
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K++ + + +D E LE+R + + + L++ +E + M L + K+ + +
Sbjct: 389 KAIEDDLMKTED-EYETLERRYANERDKAQFLSKELEHVKMEL--AKYKLAEKTETSHEQ 445
Query: 690 PMLDR-YIQEIKT--VTKKFEAVKEQCGDVDSEMTLDVATAKQVDF---KQKISTLRNRV 743
+ R +E K+ ++++ +A+KE+ + + T D+ Q D K+K++ NR
Sbjct: 446 WLFKRLQEEEAKSGHLSREVDALKEKIHEYMA--TEDLICHLQGDHSVCKKKLNQQENRN 503
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
+ +++ K+L+ Y +K+ LN ++
Sbjct: 504 RDLGREIENLTKELER-YRHFSKSLRPSLNGRR 535
Score = 36.3 bits (80), Expect = 0.66
Identities = 37/163 (22%), Positives = 71/163 (43%), Gaps = 11/163 (6%)
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
A++ + K++ L ++ K E ++QE K +K++ T + DT+
Sbjct: 11 AQLTLQRQKIQELTTNAKETHTKLALAEA-RVQEEEQKATRLEKELQTQTTKFHQDQDTI 69
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTD---ITN--WQKQDDELNEKLNGINKEELNEKESL 956
++ ++ R L L Q D TN +K ++EL + I+K E +
Sbjct: 70 MAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKEKISKGEYG-NAGI 128
Query: 957 IIKQTKLFQQKAECTGALSELKKSL---KGFRNELEKSLSKDI 996
+ + +L + + +C L++ K F+ E+EK LSK I
Sbjct: 129 MAEVEELIKMEEQCRDLNKRLERETLQSKDFKLEVEK-LSKRI 170
>AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein.
Length = 992
Score = 74.1 bits (174), Expect = 3e-12
Identities = 142/705 (20%), Positives = 304/705 (43%), Gaps = 66/705 (9%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQK-ITKLQKQTAK-LKEKEMIEENLKTKE 445
++EL I+ ++ + + + E + EL+++ +L + + KE ++ + L+ E
Sbjct: 233 QDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME 292
Query: 446 KQLIVLK---NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
++ K N ++ +LL + K + + + E +
Sbjct: 293 LRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQ 352
Query: 503 LEAERKHIRESLNER-RSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSS 561
E E +RE ++ R + A+ K + + D +S + L++E +L+S+
Sbjct: 353 KEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSMERGLRDLEEEIQMLKSN 411
Query: 562 MFIINKYKGQ-LKDNSCCPLCNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
+ + + + +K ++ +N+ + + + KLE +T +
Sbjct: 412 GALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDS 471
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ + + E+ + TE+ L R+ + +T + + ++++ E+K
Sbjct: 472 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA------EEKG 525
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T A +IH MLD +++ + KK E ++EQ D + +M+ + ++V Q +T
Sbjct: 526 TQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS---SLKERVKSLQADTTN 582
Query: 740 RNRVKTT-QKKLNAHNKKLQTLYEKKTK----AKEELLNTQKKVQDI---VNL------- 784
+ TT ++ L + ++ L E++ + +EE+ N +K ++D+ V+L
Sbjct: 583 TDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 642
Query: 785 -EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
E S L+ + LE+AL++K E ++ + + EA A
Sbjct: 643 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARAS 702
Query: 844 VEVAFNKVKSLDAEIQQHKKKN------VPREMEKIQEANDKLMEKQKQI-----MTDRQ 892
E++ ++++ L+ EI ++K ++ V R +E ++E ++ +K K+I +T RQ
Sbjct: 703 PEMS-DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQ 761
Query: 893 V--LTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITN--WQKQDDELNEKLNGINKE 948
V KK+ LK K++V K+ L + + D N Q+ D L +K + I +
Sbjct: 762 VKDQNKKVANLKH---KEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEEL 818
Query: 949 ELNEKESLII---KQTKLFQQKAECTGA---LSELKKSLKGFRNELEKSLSK--DIEKKF 1000
E +ES+ I ++ L Q+++ T A + EL +++ + ELE +K ++
Sbjct: 819 EEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSL 878
Query: 1001 REKMYELHVTK---AIDKDIREYAVALDKCLMEFHREKMENINMI 1042
EK E H+T K + E + L+ EK NI ++
Sbjct: 879 AEK--ETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 921
>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
Length = 1003
Score = 74.1 bits (174), Expect = 3e-12
Identities = 142/705 (20%), Positives = 304/705 (43%), Gaps = 66/705 (9%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQK-ITKLQKQTAK-LKEKEMIEENLKTKE 445
++EL I+ ++ + + + E + EL+++ +L + + KE ++ + L+ E
Sbjct: 244 QDELRIQRDLNQLFQQDSSSRTGEPCVAELTEENFQRLHAEHERQAKELFLLRKTLEEME 303
Query: 446 KQLIVLK---NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
++ K N ++ +LL + K + + + E +
Sbjct: 304 LRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESLLEQ 363
Query: 503 LEAERKHIRESLNER-RSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSS 561
E E +RE ++ R + A+ K + + D +S + L++E +L+S+
Sbjct: 364 KEKENSMLREEMHRRFENAPDSAKTKALQTV-IEMKDSKISSMERGLRDLEEEIQMLKSN 422
Query: 562 MFIINKYKGQ-LKDNSCCPLCNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
+ + + + +K ++ +N+ + + + KLE +T +
Sbjct: 423 GALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKLETLTNQFSDS 482
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ + + E+ + TE+ L R+ + +T + + ++++ E+K
Sbjct: 483 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA------EEKG 536
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T A +IH MLD +++ + KK E ++EQ D + +M+ + ++V Q +T
Sbjct: 537 TQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS---SLKERVKSLQADTTN 593
Query: 740 RNRVKTT-QKKLNAHNKKLQTLYEKKTK----AKEELLNTQKKVQDI---VNL------- 784
+ TT ++ L + ++ L E++ + +EE+ N +K ++D+ V+L
Sbjct: 594 TDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSE 653
Query: 785 -EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
E S L+ + LE+AL++K E ++ + + EA A
Sbjct: 654 KEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARAS 713
Query: 844 VEVAFNKVKSLDAEIQQHKKKN------VPREMEKIQEANDKLMEKQKQI-----MTDRQ 892
E++ ++++ L+ EI ++K ++ V R +E ++E ++ +K K+I +T RQ
Sbjct: 714 PEMS-DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQ 772
Query: 893 V--LTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITN--WQKQDDELNEKLNGINKE 948
V KK+ LK K++V K+ L + + D N Q+ D L +K + I +
Sbjct: 773 VKDQNKKVANLKH---KEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEEL 829
Query: 949 ELNEKESLII---KQTKLFQQKAECTGA---LSELKKSLKGFRNELEKSLSK--DIEKKF 1000
E +ES+ I ++ L Q+++ T A + EL +++ + ELE +K ++
Sbjct: 830 EEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSL 889
Query: 1001 REKMYELHVTK---AIDKDIREYAVALDKCLMEFHREKMENINMI 1042
EK E H+T K + E + L+ EK NI ++
Sbjct: 890 AEK--ETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 932
>AB023217-1|BAA76844.2| 1956|Homo sapiens KIAA1000 protein protein.
Length = 1956
Score = 73.7 bits (173), Expect = 4e-12
Identities = 137/687 (19%), Positives = 283/687 (41%), Gaps = 67/687 (9%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEKQL 448
E + + ++E E V+ +E++ L++ I+KL + ++E + ++L +E++L
Sbjct: 980 ETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKL 1039
Query: 449 IVLKNKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
L A ++L V E + A+ K E+ LE+ +
Sbjct: 1040 SSLSK----ANLKLEQQVDELEGALEQERKARMNCERELHKLEGNLKLNRESMENLESSQ 1095
Query: 508 KHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIIN 566
+H+ E L ++ EL++ K+ G T+ + T ++ L+++ +++ +
Sbjct: 1096 RHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKME 1155
Query: 567 KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA------- 619
+ + L + L + E E K++K+ D++ A
Sbjct: 1156 RERADLTQD----LADLN-ERLEEVGGSSLAQLEITKKQETKIQKLHRDMEEATLHFETT 1210
Query: 620 --SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQ 677
S KK S+ L ++ L+ + +LEK D+ ++ L VE++T + E+
Sbjct: 1211 SASLKKRHADSLAELEGQVENLQQVK-QKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEK 1269
Query: 678 KMTTAKQ-IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDV-----DSEMTLDVATAKQVD 731
T ++ +H LD+ Q + + + + G+ + E ++ + ++ +
Sbjct: 1270 LCTLYEERLHEATAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSN 1329
Query: 732 FKQKISTLRNRVKTTQKKLNAHNKKLQTL----------YEKKTKAKEELLNTQKKVQDI 781
F ++I LR +++ K +A LQ YE++ + K EL T KV
Sbjct: 1330 FTRQIEDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKV--- 1386
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
N E + +++ + A L + L+E EA RN L A
Sbjct: 1387 -NAEMVQWRMKYE-NNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQ 1444
Query: 842 AKVEVAFN---KVKSLDAEIQQHKK---KNVPREMEKIQEANDKLMEKQKQIMTDRQVLT 895
++ A + KV+S A + Q + K + +K +E+ L QK++ L
Sbjct: 1445 LELGDALSDLGKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELL 1504
Query: 896 KKIDTLKDEIAKQEVYKRD---LDDNLC-----LRKAQTDITNWQKQDDELNEKLNGINK 947
K +T ++ I QE +R+ L + + +R+ ++T +K + E+ +
Sbjct: 1505 KLKNTYEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQV 1564
Query: 948 --EE----LNEKESLIIK-QTKLFQQKAECTGALSELKKSLKGFRNELE---KSLSKDIE 997
EE L ES I+ Q +L + KAE LSE + ++ FR + + SL ++
Sbjct: 1565 TLEETEGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLD 1624
Query: 998 KKFREKMYELHVTKAIDKDIREYAVAL 1024
+ + ++ + K +++D+ E + L
Sbjct: 1625 SEAKSRIEVTRLKKKMEEDLNEMELQL 1651
Score = 51.6 bits (118), Expect = 2e-05
Identities = 118/655 (18%), Positives = 253/655 (38%), Gaps = 45/655 (6%)
Query: 395 ECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL-KEKEMIEENL--KTKEKQLIVL 451
+ + + E + VE+ E+ EL+ + KL+ + +L KE + +E L KEK+
Sbjct: 936 QLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEH 995
Query: 452 KNKHKTALMELLGNVPEK--DFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
K K+ T +E L K A + + + +++ LE +
Sbjct: 996 KVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDE 1055
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ +L + R E +++K G L ++E L+ Q L + K +
Sbjct: 1056 LEGALEQERKARMNCERELHKLEG------NLKLNRESMENLESSQRHLAEE---LRKKE 1106
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L + +G + + + + E+ T + + D +
Sbjct: 1107 LELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTR-AKMERERADLTQDL 1165
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGD- 688
LNE++ + + + QLE +T+I+ L+ +EE T+ E + K+ H D
Sbjct: 1166 ADLNERLEEVGGSSLAQLE-ITKKQETKIQKLHRDMEEATLHF---ETTSASLKKRHADS 1221
Query: 689 MPMLDRYIQEIKTVTKKFEAVKEQCG-DVDSEMT-LDVATAKQVDFKQKISTLRNRVKTT 746
+ L+ ++ ++ V +K E K +VD +T ++ T + + ++ + R+
Sbjct: 1222 LAELEGQVENLQQVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEA 1281
Query: 747 QKKLNAHNKKLQTLYEKKTK-------------AKEELLN--TQKKVQDIVNLEESKKQL 791
KL+ + L +KTK KE L+N +++K +E+ + QL
Sbjct: 1282 TAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQL 1341
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ + A ++ L+E+ E + EV + +A + + + +
Sbjct: 1342 EKETKSQSALAHALQKAQRDCDL-LREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENN 1400
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVY 911
E + KK + +++ EA + + R L ++ ++ K
Sbjct: 1401 VIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSA 1460
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECT 971
LD L+ + + +W+++ +E L+ K E ++L + KL E
Sbjct: 1461 AARLDQKQ-LQSGKA-LADWKQKHEESQALLDASQK----EVQALSTELLKLKNTYEESI 1514
Query: 972 GALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
L++ K + E+ +L+ + + + V K I+++ E V L++
Sbjct: 1515 VGQETLRRENKNLQEEI-SNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEE 1568
Score = 44.4 bits (100), Expect = 0.002
Identities = 114/610 (18%), Positives = 246/610 (40%), Gaps = 36/610 (5%)
Query: 385 KQAENELNIEECQQEINED-EKAVEQYEQEMDELSQKITKLQKQTAKLKEKEM-IEENLK 442
K+ +++ + Q+ D + EQYE+E + ++ L K A++ + M E N+
Sbjct: 1343 KETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWRMKYENNVI 1402
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPEKDFA-VTINKFECEVRNEVXXXXXXXXXXXXXXX 501
+ + L K + L E + + ++ + +++ E+
Sbjct: 1403 QRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAA 1462
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSS 561
L+ ++ ++L + + K E+ +Q LS ++ +E V Q +
Sbjct: 1463 RLDQKQLQSGKALADWKQ---KHEESQALLDASQKEVQALSTELLKLKNTYEESIVGQET 1519
Query: 562 MFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASA 621
+ NK Q + ++ G +N +E V LE+ L+R +
Sbjct: 1520 LRRENKNL-QEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEETEGALERNES 1578
Query: 622 K----KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQ 677
K + E+L K+ E+ + KD EI ++ I +L +++ S IE +
Sbjct: 1579 KILHFQLELLEAKAELERKLSEKDEEIENFRRK---QQCTIDSLQSSLDSEAKSRIEVTR 1635
Query: 678 KMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI 736
++ +M + L +++ TK ++ Q D+ +M LD +T D K+++
Sbjct: 1636 LKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDL--QMQLDDSTQLNSDLKEQV 1693
Query: 737 STLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ----DIVNLEESKKQLQ 792
+ R Q +L + + ++EELL +++ +L KK+L+
Sbjct: 1694 AVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLE 1753
Query: 793 SDCXXXXXXXXXXXXAI-TPLEVALKEKIEAK--TEVVRRNRDLIEAGSAYIAKVEVAFN 849
+D E A K IEA +E +++ +D I +E
Sbjct: 1754 ADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTIT 1813
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKL---MEKQKQIMTDRQVLTKKIDTLKDEIA 906
++ AE +Q ++++K++ +L +E + + + Q ++++ E+
Sbjct: 1814 DLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELT 1873
Query: 907 KQ-EVYKRDLDD-NLCLRKAQTDITNWQKQ----DDELNEKLNGINKE--ELNE-KESLI 957
Q E K++L + K Q + N+++Q + + N+ L+ K+ ELNE KE
Sbjct: 1874 YQAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAE 1933
Query: 958 IKQTKLFQQK 967
+ ++++ + K
Sbjct: 1934 VAESQVNKLK 1943
Score = 41.1 bits (92), Expect = 0.023
Identities = 69/299 (23%), Positives = 128/299 (42%), Gaps = 29/299 (9%)
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
K + ++++ L+ QK L + + L KAK+ L TQ+K I+ L+
Sbjct: 863 KSSEVGEEVAGLKEECAQLQKALEKSEFQREEL-----KAKQVSL-TQEKNDLILQLQAE 916
Query: 788 KKQL---QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
++ L + C + L ++E+ E +E+ R R L + ++
Sbjct: 917 QETLANVEEQCEWLIKSKIQLEARVKELSERVEEEEEINSELTARGRKLEDECFELKKEI 976
Query: 845 E-VAFNKVKS-LDAEIQQHKKKNVPREMEKIQEANDKL-------MEKQKQIMTDRQVLT 895
+ + VKS + +HK KN+ E+E + E KL E +Q + D +
Sbjct: 977 DDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEE 1036
Query: 896 KKIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEK- 953
+K+ +L K E +L+ L RKA+ + + E N KLN + E L
Sbjct: 1037 EKLSSLSKANLKLEQQVDELEGALEQERKARMNCER-ELHKLEGNLKLNRESMENLESSQ 1095
Query: 954 ----ESLIIKQTKLFQQKAEC---TGALSELKKSLKGFRNELEKSLSK-DIEKKFREKM 1004
E L K+ +L Q ++ G +++L+K++K + +++ K + E+ R KM
Sbjct: 1096 RHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQIKDLKEKLEAERTTRAKM 1154
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 73.3 bits (172), Expect = 5e-12
Identities = 156/883 (17%), Positives = 356/883 (40%), Gaps = 69/883 (7%)
Query: 193 RLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK 252
+L K ++ + + L ++ ++ Q +LE ++ +++KI N ++ +
Sbjct: 482 QLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQ---IGDKDQKIQNLEALLQKSKEN 538
Query: 253 FILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKV 312
LLE + ++ K ETA + +++ E+ T+ + + ES K +
Sbjct: 539 ISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHT-LQEQVTQLTEKLKNQSESHKQAQEN 597
Query: 313 QKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXX 372
Q E++ + D S T I + +
Sbjct: 598 LHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDI-QIKAKTELLLSAEA 656
Query: 373 XXXXXXXXXXXHKQ-AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL 431
H A+N L ++ QQE+N+ ++Q ++ + + ++L+ +
Sbjct: 657 AKTAQRADLQNHLDTAQNAL--QDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEY 714
Query: 432 KEK--------EMIEENLKTKEKQLIVLKNKHKTALMELLGNVP-EKDFAVTINKFECEV 482
KEK E +E +K E + +K + AL +L D + + ++
Sbjct: 715 KEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQL 774
Query: 483 RNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS 542
E LE+ ++ + + E ++ K + + ++ +
Sbjct: 775 EMEKEIVSSTRLDLQKKSEALESIKQKLTK--QEEEKQILKQDFETLSQETKIQHEELNN 832
Query: 543 KYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXX 602
+ TTV +LQ + ++ M ++ K +L S L N E E E
Sbjct: 833 RIQTTVTELQKVKMEKEALMTELSTVKDKLSKVS-DSLKNSKSEFEKENQKGKAAILDLE 891
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
++ ++ ++ E+ ++ + E+ ++++++ +K
Sbjct: 892 KTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNE 951
Query: 663 ETVEEITMSLIE----PEQKMTTAKQIHGDM--PMLDRYIQEIKTVTKKFEAVKEQCGDV 716
+ +++ ++ E EQK + + G++ +L + E K + +A +E +
Sbjct: 952 KEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEK 1011
Query: 717 DSEMTLDVATAK-QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
+ L K Q FKQ S R + +L A + L+++ EK + A+E+L++ +
Sbjct: 1012 EKISVLQNNYEKSQETFKQLQSDFYGR----ESELLATRQDLKSVEEKLSLAQEDLISNR 1067
Query: 776 KKVQD----IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
++ + I L+ +K L+ D A+ ++ KEK + E+V
Sbjct: 1068 NQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQ---KEKSLKEKELVNEKS 1124
Query: 832 DLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
L E I +++ K + L+ E++ HK +++ +E+ +++A L++++ +
Sbjct: 1125 KLAE-----IEEIKCRQEKEITKLNEELKSHKLESI-KEITNLKDAKQLLIQQKLE---- 1174
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
L K D+LK + +++ ++ L D ++K + ++ +K+ E KL+ E+
Sbjct: 1175 ---LQGKADSLKAAVEQEKRNQQILKDQ--VKKEEEEL---KKEFIEKEAKLH----SEI 1222
Query: 951 NEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK--DIEKKFREKMYELH 1008
EKE + K + +A+ T ++ L ++L + E + S + ++EK+ + E+
Sbjct: 1223 KEKE---VGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIA 1279
Query: 1009 VTKA-IDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKI 1050
V +A + + E L++CL ++E + + EL RK+
Sbjct: 1280 VLEATVQNNQDERRALLERCLK--GEGEIEKLQTKVLELQRKL 1320
Score = 69.3 bits (162), Expect = 8e-11
Identities = 143/731 (19%), Positives = 297/731 (40%), Gaps = 81/731 (11%)
Query: 398 QEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE--------KEMIEENLKTKE---K 446
QE+ + + +V + Q+ L++ + K ++ KL+E K+ I+ L K+ +
Sbjct: 288 QELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQ 347
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINKFE-CEVRNEVXXXXXXXXXXXXXXXXLEA 505
QL + +T+L + + EK A K E EV + E
Sbjct: 348 QLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQ 407
Query: 506 ERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFII 565
++ +N+ S+L + E ++ +A G LS EKL D++ + +
Sbjct: 408 HGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSS-----EKLMDKEQQVADLQLKL 462
Query: 566 NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDE 625
++ + QLK+ N +E + T L+ A ++
Sbjct: 463 SRLEEQLKEK---------VTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQ 513
Query: 626 ILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQI 685
+L + + + KD +I LE + I L + E++ + E + Q+
Sbjct: 514 VL--RQIGD-----KDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQL 566
Query: 686 ----HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT--LDVATAKQVDFKQKISTL 739
H + + +++K ++ + +E D E L A + + + ++ L
Sbjct: 567 QEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNEL 626
Query: 740 RNRVKTTQKK-------LNAHNKKLQTLYEKKTKAKEELLNTQKKVQD-IVNLEESKKQL 791
+++ +++K + A + L + KT + +L N Q+ + + ++ ++
Sbjct: 627 NSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKI 686
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKE------KIEAKTEVVRRNRDLIEAGSAYIAKVE 845
+ + LE LKE +E KTE + +EA S +E
Sbjct: 687 TTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADS-----LE 741
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ--KQIMTDRQVLTKKIDTLKD 903
V +K ++L ++QQ ++ N E+ + + MEK+ D Q ++ ++++K
Sbjct: 742 VKASKEQALQ-DLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQ 800
Query: 904 EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKL 963
++ KQE K+ L + +T I Q +ELN ++ + + E + + +++ L
Sbjct: 801 KLTKQEEEKQILKQDFETLSQETKI-----QHEELNNRI----QTTVTELQKVKMEKEAL 851
Query: 964 FQQKAECTGALSELKKSLKGFRNELEKSLSK------DIEKKFREKMYELHV-TKAIDKD 1016
+ + LS++ SLK ++E EK K D+EK +E ++L V + K+
Sbjct: 852 MTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKE 911
Query: 1017 IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGN---LTVESER 1073
+E +L+K H+ K+E +N + +L + + E + +GN L SE+
Sbjct: 912 QKELKKSLEKEKEASHQLKLE-LNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQ 970
Query: 1074 RKYDYRVVQSK 1084
+K +Q +
Sbjct: 971 KKKQIEALQGE 981
Score = 50.0 bits (114), Expect = 5e-05
Identities = 79/420 (18%), Positives = 174/420 (41%), Gaps = 52/420 (12%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+L+ + + L+ A + I MK L E+ TEI ++ + + + + + V
Sbjct: 136 ELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTR 195
Query: 668 ITMSLIEP----EQKMTTAKQIHG--DMPMLDRYIQEIKTVT--------KKFEAVKEQC 713
+T L + + T Q G D+ +L + + +++T+ ++ E +K++C
Sbjct: 196 LTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDEC 255
Query: 714 GDVDSEMTLDVATAKQVDFK-----QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAK 768
+ S+ AT Q+ + Q+++ ++ + +N +K QTL E K +
Sbjct: 256 KKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKE 315
Query: 769 EELLNTQKKVQDIV----NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
++ ++K + N++ + Q DC ++ + V L EK EA
Sbjct: 316 QDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQ 375
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH-------------KKKNVPREM- 870
++ +L E + Y ++ F +++ E +QH K R++
Sbjct: 376 KL---KEELSEVETKY-QHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQLG 431
Query: 871 -------EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
E+ Q +++KLM+K++Q+ + L++ + LK+++ + LD +
Sbjct: 432 EAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQ 491
Query: 924 AQTDITNWQKQDDELNEKLNGINK--EELNEKESLIIKQTKLFQQKAECTGALSELKKSL 981
Q + Q +L E N + + ++ +K+ I L Q+ E L + ++ L
Sbjct: 492 EQQALQ--QSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDL 549
Score = 44.0 bits (99), Expect = 0.003
Identities = 77/385 (20%), Positives = 157/385 (40%), Gaps = 22/385 (5%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSR----CADLDILMHEELG 147
KQLE+ + + + + K + L+S + + + K + + + + HEEL
Sbjct: 772 KQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELN 831
Query: 148 VSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKL 207
+ + + + + E VK++ ++ D+ K S + K+ +K A L L
Sbjct: 832 NRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKS-EFEKENQKGKAAILDL 890
Query: 208 LENYATTVKAKQKELEDSYKKNTSFNK--EEEKIANEKSSNEIEYNKFILLESQNQEKID 265
+ Q ++E++ K+ K E+EK A+ + E+ + L+++QN K +
Sbjct: 891 EKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQN 950
Query: 266 KRNEQIVETAKIAEIENITEVQTN--EEAENATK-TILEKVESLKSDHKVQKSQADEE-- 320
++ EQ ++ I E++ +E + E + K +L+K E L++ + Q +QA +E
Sbjct: 951 EKEEQQLQ-GNINELKQSSEQKKKQIEALQGELKIAVLQKTE-LENKLQQQLTQAAQELA 1008
Query: 321 -EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXX 379
EK+ + + D+ S +
Sbjct: 1009 AEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRN 1068
Query: 380 XXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEE 439
+ EL + E + +K EQ++ E + + +QK+ + LKEKE++ E
Sbjct: 1069 QIGNQNKLIQELKTAKATLEQDSAKK-----EQQLQERCKALQDIQKEKS-LKEKELVNE 1122
Query: 440 NLKTKE-KQLIVLKNKHKTALMELL 463
K E +++ + K T L E L
Sbjct: 1123 KSKLAEIEEIKCRQEKEITKLNEEL 1147
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 73.3 bits (172), Expect = 5e-12
Identities = 88/454 (19%), Positives = 200/454 (44%), Gaps = 35/454 (7%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
KLE +T + + + + E+ + TE+ L R+ + +T + + +++
Sbjct: 488 KLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQD 547
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ E+K T A +IH MLD +++ + KK E ++EQ D + +M+ +
Sbjct: 548 MA------EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS---SLK 598
Query: 728 KQVDFKQKISTLRNRVKTT-QKKLNAHNKKLQTLYEKKTK----AKEELLNTQKKVQDI- 781
++V Q +T + TT ++ L + ++ L E++ + +EE+ N +K ++D+
Sbjct: 599 ERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLK 658
Query: 782 --VNL--------EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
V+L E S L+ + LE+AL++K E ++ + +
Sbjct: 659 EKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLK 718
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDR 891
EA A E++ ++++ L+ EI ++K E K Q D+L+E K++ ++
Sbjct: 719 KAHEAALEARASPEMS-DRIQHLEREITRYKD-----ESSKAQAEVDRLLEILKEVENEK 772
Query: 892 QVLTKKIDTLKDEIAKQEVYKRDL--DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
KKI L+ ++ Q +L + + +K+ + ++++D LN+ + ++
Sbjct: 773 NDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL-QDS 831
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
L +K+ I + + ++ + T + + R EK + +++ + EL
Sbjct: 832 LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV-EELLMAMEKVKQELES 890
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENINMII 1043
KA ++ + L E+ +++ ++
Sbjct: 891 MKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL 924
Score = 67.7 bits (158), Expect = 2e-10
Identities = 108/555 (19%), Positives = 238/555 (42%), Gaps = 38/555 (6%)
Query: 509 HIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKY 568
H+ L ++ E + +++++ P T +E + + ++ + + +
Sbjct: 345 HLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS 628
LK N R E E + N K+E++ E+L A+ +E+
Sbjct: 405 IQMLKSNGALSTEER--EEEMKQMEVYRSHSKFMKN---KVEQLKEELSSKEAQWEELKK 459
Query: 629 MKS-LNEKITTLK------DTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT 681
+ L +I +K DTE+ L+ ++ + Q + +E + SL EQ+
Sbjct: 460 KAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQR--- 516
Query: 682 AKQIHGDMPMLDRYIQEIKTV----TKKFEAVKE----QCGDV-DSEMTLDVATAKQVDF 732
A + ++ L ++E +T+ TK+ + + E Q G++ D + LDV K
Sbjct: 517 AAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVL 576
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-NLEESKKQL 791
++KI L+ +++ +K++++ +++++L T L ++ + + +E K+Q
Sbjct: 577 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQR 636
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
D + L+ + +E DL E S+ + +++
Sbjct: 637 DRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRL 696
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLME-KQKQIMTDR-QVLTKKIDTLKDEIAKQE 909
K+L+ ++Q K++ + E ++++A++ +E + M+DR Q L ++I KDE +K +
Sbjct: 697 KTLEIALEQKKEECLKME-SQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQ 755
Query: 910 VYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKA 968
++D L L++ + + + K+ EL ++ NK+ N K +++ K Q
Sbjct: 756 A---EVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLE 812
Query: 969 ECTGALSELKKSLKGFRNELEKSLSK--DIEKKFREKMY---ELHVTKAIDKDIREYA-V 1022
E L S + ++ L K + ++E+ RE + E + A ++ R A
Sbjct: 813 EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEK 872
Query: 1023 ALDKCLMEFHREKME 1037
+++ LM + K E
Sbjct: 873 QVEELLMAMEKVKQE 887
Score = 62.5 bits (145), Expect = 9e-09
Identities = 128/656 (19%), Positives = 268/656 (40%), Gaps = 51/656 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDE--LSQKITKLQ-KQTAKLKEKEM----IEEN 440
E EL IE +Q +N ++++++ + + LS K T+ ++T +L E EM +E
Sbjct: 290 EMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESL 349
Query: 441 LKTKEKQLIVLKNK-HK-------TALMELLGNVPE-KDFAVT-----INKFECEVRNEV 486
L+ KEK+ +L+ + H+ +A + L V E KD ++ + E E++
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLK 409
Query: 487 XXXXXXXXXXXXXXXXLEAERKH---IRESLNERRSELTKAE----DKIYKACGTQP--- 536
+E R H ++ + + + EL+ E + KA G Q
Sbjct: 410 SNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIG 469
Query: 537 -YDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGF-ENESEXXXX 594
LS+ T + LQ + L + ++ LK++ + E +
Sbjct: 470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRL 529
Query: 595 XXXXXXXXMNVPGK-LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVD 653
+N K ++ + E+ + + ++ M + E+ + +I L++++ D
Sbjct: 530 RLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 589
Query: 654 VDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQC 713
+ Q+ +L E V+ + + +TT ++ + +R I+ +K + E K++
Sbjct: 590 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK---ERTIERLKEQRDRDEREKQEE 646
Query: 714 GD---VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK---LQTLYEKKTKA 767
D D + + + Q D +K ++L + + ++ KK L+TL +
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 706
Query: 768 KEELLNTQ---KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
KEE L + KK + + ++ + + + +E
Sbjct: 707 KEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
EV D + + +V+ KV +L + Q KKK+ + +E+ + D L +
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA-QMLEEARRREDNLNDSS 825
Query: 885 KQIMTDRQVLTKKIDTLKD-EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLN 943
+Q+ L KK D +++ E A +E + + + L + ++ TN +KQ +EL +
Sbjct: 826 QQLQDS---LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ +E + K L Q L +++ T +E +K L+ +++L I +K
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK 938
Score = 52.0 bits (119), Expect = 1e-05
Identities = 97/461 (21%), Positives = 191/461 (41%), Gaps = 27/461 (5%)
Query: 647 LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKF 706
LE+ + ++TQ +TLN E I L + K +AK D R + E +
Sbjct: 288 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHER-TRRLAEAEMHVHHL 346
Query: 707 EAVKEQCGDVDSEMTLDV-ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
E++ EQ +S + ++ + K L+ ++ K+++ + L+ L E+
Sbjct: 347 ESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQ 406
Query: 766 KAKEE-LLNTQKKVQDIVNLE----ESK--KQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
K L+T+++ +++ +E SK K + L+
Sbjct: 407 MLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQA 466
Query: 819 KI-EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK--IQE 875
+I + K E+ R++ +L+ A K+E N+ I+ K+ +E +Q
Sbjct: 467 EIGQVKQELSRKDTELL----ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQT 522
Query: 876 ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQD 935
D L + ++ T TK+I + +E Q DL D L +++ + ++ QK+
Sbjct: 523 EVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVL--QKKI 580
Query: 936 DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKD 995
+ L E+L K+ + KE + L AL+ L+++L +E+ L +
Sbjct: 581 ENLQEQLRDKEKQMSSLKE----RVKSLQADTTNTDTALTTLEEALAEKERTIER-LKEQ 635
Query: 996 IEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM---ENINMIIRELWRKIYR 1052
++ REK E+ K KD++E L L E + E+ + + +K R
Sbjct: 636 RDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSR 695
Query: 1053 GNDIDY-IEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMR 1092
++ +E K E L +ES+ +K ++++ E+ R
Sbjct: 696 LKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDR 736
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 73.3 bits (172), Expect = 5e-12
Identities = 88/454 (19%), Positives = 200/454 (44%), Gaps = 35/454 (7%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
KLE +T + + + + E+ + TE+ L R+ + +T + + +++
Sbjct: 488 KLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQD 547
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ E+K T A +IH MLD +++ + KK E ++EQ D + +M+ +
Sbjct: 548 MA------EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS---SLK 598
Query: 728 KQVDFKQKISTLRNRVKTT-QKKLNAHNKKLQTLYEKKTK----AKEELLNTQKKVQDI- 781
++V Q +T + TT ++ L + ++ L E++ + +EE+ N +K ++D+
Sbjct: 599 ERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLK 658
Query: 782 --VNL--------EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
V+L E S L+ + LE+AL++K E ++ + +
Sbjct: 659 EKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLK 718
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDR 891
EA A E++ ++++ L+ EI ++K E K Q D+L+E K++ ++
Sbjct: 719 KAHEAALEARASPEMS-DRIQHLEREITRYKD-----ESSKAQAEVDRLLEILKEVENEK 772
Query: 892 QVLTKKIDTLKDEIAKQEVYKRDL--DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
KKI L+ ++ Q +L + + +K+ + ++++D LN+ + ++
Sbjct: 773 NDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL-QDS 831
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
L +K+ I + + ++ + T + + R EK + +++ + EL
Sbjct: 832 LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV-EELLMAMEKVKQELES 890
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENINMII 1043
KA ++ + L E+ +++ ++
Sbjct: 891 MKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL 924
Score = 67.7 bits (158), Expect = 2e-10
Identities = 108/555 (19%), Positives = 238/555 (42%), Gaps = 38/555 (6%)
Query: 509 HIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKY 568
H+ L ++ E + +++++ P T +E + + ++ + + +
Sbjct: 345 HLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS 628
LK N R E E + N K+E++ E+L A+ +E+
Sbjct: 405 IQMLKSNGALSTEER--EEEMKQMEVYRSHSKFMKN---KVEQLKEELSSKEAQWEELKK 459
Query: 629 MKS-LNEKITTLK------DTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT 681
+ L +I +K DTE+ L+ ++ + Q + +E + SL EQ+
Sbjct: 460 KAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQR--- 516
Query: 682 AKQIHGDMPMLDRYIQEIKTV----TKKFEAVKE----QCGDV-DSEMTLDVATAKQVDF 732
A + ++ L ++E +T+ TK+ + + E Q G++ D + LDV K
Sbjct: 517 AAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVL 576
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-NLEESKKQL 791
++KI L+ +++ +K++++ +++++L T L ++ + + +E K+Q
Sbjct: 577 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQR 636
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
D + L+ + +E DL E S+ + +++
Sbjct: 637 DRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRL 696
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLME-KQKQIMTDR-QVLTKKIDTLKDEIAKQE 909
K+L+ ++Q K++ + E ++++A++ +E + M+DR Q L ++I KDE +K +
Sbjct: 697 KTLEIALEQKKEECLKME-SQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQ 755
Query: 910 VYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKA 968
++D L L++ + + + K+ EL ++ NK+ N K +++ K Q
Sbjct: 756 A---EVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLE 812
Query: 969 ECTGALSELKKSLKGFRNELEKSLSK--DIEKKFREKMY---ELHVTKAIDKDIREYA-V 1022
E L S + ++ L K + ++E+ RE + E + A ++ R A
Sbjct: 813 EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEK 872
Query: 1023 ALDKCLMEFHREKME 1037
+++ LM + K E
Sbjct: 873 QVEELLMAMEKVKQE 887
Score = 62.5 bits (145), Expect = 9e-09
Identities = 128/656 (19%), Positives = 268/656 (40%), Gaps = 51/656 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDE--LSQKITKLQ-KQTAKLKEKEM----IEEN 440
E EL IE +Q +N ++++++ + + LS K T+ ++T +L E EM +E
Sbjct: 290 EMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESL 349
Query: 441 LKTKEKQLIVLKNK-HK-------TALMELLGNVPE-KDFAVT-----INKFECEVRNEV 486
L+ KEK+ +L+ + H+ +A + L V E KD ++ + E E++
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLK 409
Query: 487 XXXXXXXXXXXXXXXXLEAERKH---IRESLNERRSELTKAE----DKIYKACGTQP--- 536
+E R H ++ + + + EL+ E + KA G Q
Sbjct: 410 SNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIG 469
Query: 537 -YDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGF-ENESEXXXX 594
LS+ T + LQ + L + ++ LK++ + E +
Sbjct: 470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRL 529
Query: 595 XXXXXXXXMNVPGK-LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVD 653
+N K ++ + E+ + + ++ M + E+ + +I L++++ D
Sbjct: 530 RLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 589
Query: 654 VDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQC 713
+ Q+ +L E V+ + + +TT ++ + +R I+ +K + E K++
Sbjct: 590 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK---ERTIERLKEQRDRDEREKQEE 646
Query: 714 GD---VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK---LQTLYEKKTKA 767
D D + + + Q D +K ++L + + ++ KK L+TL +
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 706
Query: 768 KEELLNTQ---KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
KEE L + KK + + ++ + + + +E
Sbjct: 707 KEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
EV D + + +V+ KV +L + Q KKK+ + +E+ + D L +
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA-QMLEEARRREDNLNDSS 825
Query: 885 KQIMTDRQVLTKKIDTLKD-EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLN 943
+Q+ L KK D +++ E A +E + + + L + ++ TN +KQ +EL +
Sbjct: 826 QQLQDS---LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ +E + K L Q L +++ T +E +K L+ +++L I +K
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK 938
Score = 52.0 bits (119), Expect = 1e-05
Identities = 97/461 (21%), Positives = 191/461 (41%), Gaps = 27/461 (5%)
Query: 647 LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKF 706
LE+ + ++TQ +TLN E I L + K +AK D R + E +
Sbjct: 288 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHER-TRRLAEAEMHVHHL 346
Query: 707 EAVKEQCGDVDSEMTLDV-ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
E++ EQ +S + ++ + K L+ ++ K+++ + L+ L E+
Sbjct: 347 ESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQ 406
Query: 766 KAKEE-LLNTQKKVQDIVNLE----ESK--KQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
K L+T+++ +++ +E SK K + L+
Sbjct: 407 MLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQA 466
Query: 819 KI-EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK--IQE 875
+I + K E+ R++ +L+ A K+E N+ I+ K+ +E +Q
Sbjct: 467 EIGQVKQELSRKDTELL----ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQT 522
Query: 876 ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQD 935
D L + ++ T TK+I + +E Q DL D L +++ + ++ QK+
Sbjct: 523 EVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVL--QKKI 580
Query: 936 DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKD 995
+ L E+L K+ + KE + L AL+ L+++L +E+ L +
Sbjct: 581 ENLQEQLRDKEKQMSSLKE----RVKSLQADTTNTDTALTTLEEALAEKERTIER-LKEQ 635
Query: 996 IEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM---ENINMIIRELWRKIYR 1052
++ REK E+ K KD++E L L E + E+ + + +K R
Sbjct: 636 RDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSR 695
Query: 1053 GNDIDY-IEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMR 1092
++ +E K E L +ES+ +K ++++ E+ R
Sbjct: 696 LKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDR 736
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 73.3 bits (172), Expect = 5e-12
Identities = 88/454 (19%), Positives = 200/454 (44%), Gaps = 35/454 (7%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
KLE +T + + + + E+ + TE+ L R+ + +T + + +++
Sbjct: 488 KLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQD 547
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ E+K T A +IH MLD +++ + KK E ++EQ D + +M+ +
Sbjct: 548 MA------EEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS---SLK 598
Query: 728 KQVDFKQKISTLRNRVKTT-QKKLNAHNKKLQTLYEKKTK----AKEELLNTQKKVQDI- 781
++V Q +T + TT ++ L + ++ L E++ + +EE+ N +K ++D+
Sbjct: 599 ERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLK 658
Query: 782 --VNL--------EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
V+L E S L+ + LE+AL++K E ++ + +
Sbjct: 659 EKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLK 718
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDR 891
EA A E++ ++++ L+ EI ++K E K Q D+L+E K++ ++
Sbjct: 719 KAHEAALEARASPEMS-DRIQHLEREITRYKD-----ESSKAQAEVDRLLEILKEVENEK 772
Query: 892 QVLTKKIDTLKDEIAKQEVYKRDL--DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
KKI L+ ++ Q +L + + +K+ + ++++D LN+ + ++
Sbjct: 773 NDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL-QDS 831
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
L +K+ I + + ++ + T + + R EK + +++ + EL
Sbjct: 832 LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQV-EELLMAMEKVKQELES 890
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENINMII 1043
KA ++ + L E+ +++ ++
Sbjct: 891 MKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVL 924
Score = 67.7 bits (158), Expect = 2e-10
Identities = 108/555 (19%), Positives = 238/555 (42%), Gaps = 38/555 (6%)
Query: 509 HIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKY 568
H+ L ++ E + +++++ P T +E + + ++ + + +
Sbjct: 345 HLESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEE 404
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS 628
LK N R E E + N K+E++ E+L A+ +E+
Sbjct: 405 IQMLKSNGALSTEER--EEEMKQMEVYRSHSKFMKN---KVEQLKEELSSKEAQWEELKK 459
Query: 629 MKS-LNEKITTLK------DTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT 681
+ L +I +K DTE+ L+ ++ + Q + +E + SL EQ+
Sbjct: 460 KAAGLQAEIGQVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQR--- 516
Query: 682 AKQIHGDMPMLDRYIQEIKTV----TKKFEAVKE----QCGDV-DSEMTLDVATAKQVDF 732
A + ++ L ++E +T+ TK+ + + E Q G++ D + LDV K
Sbjct: 517 AAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVL 576
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-NLEESKKQL 791
++KI L+ +++ +K++++ +++++L T L ++ + + +E K+Q
Sbjct: 577 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQR 636
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
D + L+ + +E DL E S+ + +++
Sbjct: 637 DRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRL 696
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLME-KQKQIMTDR-QVLTKKIDTLKDEIAKQE 909
K+L+ ++Q K++ + E ++++A++ +E + M+DR Q L ++I KDE +K +
Sbjct: 697 KTLEIALEQKKEECLKME-SQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQ 755
Query: 910 VYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKA 968
++D L L++ + + + K+ EL ++ NK+ N K +++ K Q
Sbjct: 756 A---EVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLE 812
Query: 969 ECTGALSELKKSLKGFRNELEKSLSK--DIEKKFREKMY---ELHVTKAIDKDIREYA-V 1022
E L S + ++ L K + ++E+ RE + E + A ++ R A
Sbjct: 813 EARRREDNLNDSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEK 872
Query: 1023 ALDKCLMEFHREKME 1037
+++ LM + K E
Sbjct: 873 QVEELLMAMEKVKQE 887
Score = 62.5 bits (145), Expect = 9e-09
Identities = 128/656 (19%), Positives = 268/656 (40%), Gaps = 51/656 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDE--LSQKITKLQ-KQTAKLKEKEM----IEEN 440
E EL IE +Q +N ++++++ + + LS K T+ ++T +L E EM +E
Sbjct: 290 EMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHHLESL 349
Query: 441 LKTKEKQLIVLKNK-HK-------TALMELLGNVPE-KDFAVT-----INKFECEVRNEV 486
L+ KEK+ +L+ + H+ +A + L V E KD ++ + E E++
Sbjct: 350 LEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQMLK 409
Query: 487 XXXXXXXXXXXXXXXXLEAERKH---IRESLNERRSELTKAE----DKIYKACGTQP--- 536
+E R H ++ + + + EL+ E + KA G Q
Sbjct: 410 SNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQAEIG 469
Query: 537 -YDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGF-ENESEXXXX 594
LS+ T + LQ + L + ++ LK++ + E +
Sbjct: 470 QVKQELSRKDTELLALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRL 529
Query: 595 XXXXXXXXMNVPGK-LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVD 653
+N K ++ + E+ + + ++ M + E+ + +I L++++ D
Sbjct: 530 RLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRD 589
Query: 654 VDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQC 713
+ Q+ +L E V+ + + +TT ++ + +R I+ +K + E K++
Sbjct: 590 KEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK---ERTIERLKEQRDRDEREKQEE 646
Query: 714 GD---VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK---LQTLYEKKTKA 767
D D + + + Q D +K ++L + + ++ KK L+TL +
Sbjct: 647 IDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQK 706
Query: 768 KEELLNTQ---KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
KEE L + KK + + ++ + + + +E
Sbjct: 707 KEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILK 766
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
EV D + + +V+ KV +L + Q KKK+ + +E+ + D L +
Sbjct: 767 EVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSA-QMLEEARRREDNLNDSS 825
Query: 885 KQIMTDRQVLTKKIDTLKD-EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLN 943
+Q+ L KK D +++ E A +E + + + L + ++ TN +KQ +EL +
Sbjct: 826 QQLQDS---LRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ +E + K L Q L +++ T +E +K L+ +++L I +K
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK 938
Score = 52.0 bits (119), Expect = 1e-05
Identities = 97/461 (21%), Positives = 191/461 (41%), Gaps = 27/461 (5%)
Query: 647 LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKF 706
LE+ + ++TQ +TLN E I L + K +AK D R + E +
Sbjct: 288 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHER-TRRLAEAEMHVHHL 346
Query: 707 EAVKEQCGDVDSEMTLDV-ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
E++ EQ +S + ++ + K L+ ++ K+++ + L+ L E+
Sbjct: 347 ESLLEQKEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDLEEEIQ 406
Query: 766 KAKEE-LLNTQKKVQDIVNLE----ESK--KQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
K L+T+++ +++ +E SK K + L+
Sbjct: 407 MLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKAAGLQA 466
Query: 819 KI-EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK--IQE 875
+I + K E+ R++ +L+ A K+E N+ I+ K+ +E +Q
Sbjct: 467 EIGQVKQELSRKDTELL----ALQTKLETLTNQFSDSKQHIEVLKESLTAKEQRAAILQT 522
Query: 876 ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQD 935
D L + ++ T TK+I + +E Q DL D L +++ + ++ QK+
Sbjct: 523 EVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVL--QKKI 580
Query: 936 DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKD 995
+ L E+L K+ + KE + L AL+ L+++L +E+ L +
Sbjct: 581 ENLQEQLRDKEKQMSSLKE----RVKSLQADTTNTDTALTTLEEALAEKERTIER-LKEQ 635
Query: 996 IEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM---ENINMIIRELWRKIYR 1052
++ REK E+ K KD++E L L E + E+ + + +K R
Sbjct: 636 RDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSR 695
Query: 1053 GNDIDY-IEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMR 1092
++ +E K E L +ES+ +K ++++ E+ R
Sbjct: 696 LKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDR 736
>AF155115-1|AAD42881.1| 472|Homo sapiens NY-REN-58 antigen protein.
Length = 472
Score = 71.3 bits (167), Expect = 2e-11
Identities = 93/421 (22%), Positives = 186/421 (44%), Gaps = 30/421 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIEENLKT 443
++ + EL + ++ +D K VEQ +E L QK+ L+ + A+LK EKE E ++
Sbjct: 59 EEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVEN 118
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFA-VTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
++ + V + A + LG EK A + + E E+++
Sbjct: 119 AQR-IQVRQLAEMQATVRSLG--AEKQSANLRAERLEKELQSSSEQNTFLINKLHKAERE 175
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
+ ++E + + E+T + K+ A + +K + ++ LQ + +L+++
Sbjct: 176 INTLSSKVKELKHSNKLEIT--DIKLETARAKSELERERNKLQSELDGLQSDNEILKAA- 232
Query: 563 FIINKYKGQL--KDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEK--VTEDLQR 618
+ +K L KD E + N LEK V D+ R
Sbjct: 233 --VEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWR 290
Query: 619 ASAKK--DEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
S K +E L + E+IT + + +L+++IV ++ K NE ++ +
Sbjct: 291 QSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNEN-SDLKQQISSL 349
Query: 676 EQKMTTAKQIHGDM----PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD 731
+ ++T+ Q D+ ML ++ +K + F + E+ +++E TL+ KQ+
Sbjct: 350 QIQVTSLAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEKA-QLEAEKTLE---EKQIQ 405
Query: 732 FKQKISTLRNRVKTTQKKLNAHNKKLQ--TLYEKKTKAKEELLNTQKKVQDIVNLEESKK 789
+ ++ L +R+ ++K N +KLQ + +KK K+ E N K++Q+ V + E+KK
Sbjct: 406 WLEEKHKLHDRITDREEKYNQAKEKLQRAAIAQKKRKSLHE--NKLKRLQEKVEVLEAKK 463
Query: 790 Q 790
+
Sbjct: 464 E 464
>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
Length = 1583
Score = 70.9 bits (166), Expect = 3e-11
Identities = 130/626 (20%), Positives = 264/626 (42%), Gaps = 58/626 (9%)
Query: 402 EDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKE-----KQLIVLKN--- 453
E++ + Q E+ S+ +K+ +KE E ++ L+ KE +LI+LK+
Sbjct: 773 ENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLA 832
Query: 454 KHKTALMELLGNVPEKDFAVTINKFECEVRNE-VXXXXXXXXXXXXXXXXLEAERKHIRE 512
K + + L +V E + + + EC+ + E + E + ++E
Sbjct: 833 KSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKE 892
Query: 513 SLNERRSELTKAEDKIYKAC-GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQ 571
L RSE + + G + Y L +Y E+L E+ + I Q
Sbjct: 893 ELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQ 952
Query: 572 LKDNSC-CPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMK 630
L++++ C N +NE + LE ++QRA A D+ L +
Sbjct: 953 LRNSTLQCETINS--DNEDLLARIETLQSNAKL-----LEVQILEVQRAKAMVDKELEAE 1005
Query: 631 SLNEKITTLKD--TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGD 688
L +K +K+ T + +LE+ V + Q K L +T++E+ L++ + + TT +
Sbjct: 1006 KL-QKEQKIKEHATTVNELEELQVQLQKQKKQLQKTMQEL--ELVKKDAQQTTLM----N 1058
Query: 689 MPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQK 748
M + D Y + +K + +K + D++ E+ + KQK TL+ + + Q
Sbjct: 1059 MEIAD-YERLMKELNQKLTNKNNKIEDLEQEIKIQ---------KQKQETLQEEITSLQS 1108
Query: 749 KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXA 808
+ + +K + + K K+EL ++++ D + L+ S K
Sbjct: 1109 SVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAE 1168
Query: 809 ITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPR 868
IT + + E + KT + R L SAY +V + ++ AE + V
Sbjct: 1169 ITSEKHKIHEHL--KTSAEQHQRTL----SAYQQRVTALQEECRAAKAE-----QATVTS 1217
Query: 869 EME--KIQEANDKLMEKQKQI-MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQ 925
E E K++ N +K K + + + ++ + L+ I + ++ +D +NL +
Sbjct: 1218 EFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQIN--V 1275
Query: 926 TDITNWQKQDDELNEKLNGINKEELNE----KESLIIKQTKLFQQKAECTGALSELKKSL 981
+++ Q + D L E+ N + +E +++ +E L Q++ K+E T +S+L
Sbjct: 1276 SELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQN 1335
Query: 982 KGFRNELEKSLSKDIEKKFREKMYEL 1007
+ RN + + ++++ R+ + L
Sbjct: 1336 EVLRNSFRDQV-RHLQEEHRKTVETL 1360
Score = 60.9 bits (141), Expect = 3e-08
Identities = 135/703 (19%), Positives = 291/703 (41%), Gaps = 74/703 (10%)
Query: 386 QAENELNIEECQQEINEDEKAVEQY----EQEMDELS--QKITKLQKQTAKLKEKEMIEE 439
Q +E N+++ Q+EI + E+ ++++D + +K T Q Q + ++
Sbjct: 72 QNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQK 131
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVPE--KDFAVTINKFECEVRNEVXXXXXXXXXXX 497
N+ + +++L+ LK H+ + EL+ + K+ INK E++ +
Sbjct: 132 NINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLN-ELKENLVKQCEASEKNI 190
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGT-QPYDVTLSKYTTTVEKLQDEQN 556
E E +++R++ + + + + Q + + T+++L+ + +
Sbjct: 191 QKKY--ECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHS 248
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPG-KLEKVTED 615
+L+ + +N K +L+ ++ F +E E G +EK+ +
Sbjct: 249 ILKDEVTYMNNLKLKLEMDA--QHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSE 306
Query: 616 LQRASAK--------KDEILSMKSLNEK-ITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L + + E+ S+K ++K I+ L +T + EK + + +I+ L E E
Sbjct: 307 LAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCE 366
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIK-TVTKKFEAVKEQCGDVDSEMTLDVA 725
+ E ++ + + + M +L + E ++++FE++K+Q E+ +
Sbjct: 367 NLQQ---EKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLR 423
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD-IVNL 784
TA F +K + L T +L N+KL + E + + + N Q+K +++L
Sbjct: 424 TA----FTEKDALLE-----TVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSL 474
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
+ L+ I L+ + +E + R R ++E G KV
Sbjct: 475 SQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGK----KV 530
Query: 845 EVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLK 902
E L+ ++ + + +E ++ + +KLM + K + D++VL+ ++ +L
Sbjct: 531 EQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLY 590
Query: 903 DEIAKQEVYKRDLDDNLCLRKAQTD-------ITNWQKQDDELNEKLNGINKEELNEKES 955
+E K K+ L +L + +Q + IT +K+ + E+ + +NK NE+
Sbjct: 591 EENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQ 650
Query: 956 LIIKQTKLF-----------------------QQKAECTGALSELKKSLKGFRNELEKSL 992
+ +T+L+ Q E ++E K +L R+E L
Sbjct: 651 KLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLEL 710
Query: 993 SKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
K+I+ E + + K++ +D + V L K L E EK
Sbjct: 711 EKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEK 753
Score = 54.0 bits (124), Expect = 3e-06
Identities = 124/624 (19%), Positives = 263/624 (42%), Gaps = 45/624 (7%)
Query: 384 HKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENL 441
H++ +N E ++ I E K VEQ Q EL QK+ +L + LKEK+ ++ L
Sbjct: 506 HEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKL 565
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
+ Q+ VL ++ K L + ++ E++ ++ K + EV
Sbjct: 566 EKLMVQMKVL-SEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHIT 624
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSS 561
LE + + + E + ++L + E TQ Y L + + V + +E++V+ +
Sbjct: 625 QLEKKLQLMVEE-QDNLNKLLENEQVQKLFVKTQLYGF-LKEMGSEVSEDSEEKDVV-NV 681
Query: 562 MFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASA 621
+ + + ++ + CN F+ + + + E++ L+
Sbjct: 682 LQAVGESLAKINEEK----CNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLR--DY 735
Query: 622 KKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN--ETVEEITM----SLIEP 675
+++++L K L E + + + LE + + T+++ N VEE++ S I
Sbjct: 736 EQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHN 795
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFK-- 733
E++ K+ P+L++ +E++ + +K+ S +++ K+++ K
Sbjct: 796 EKEKCFIKEHENLKPLLEQ--KELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIE 853
Query: 734 ----------QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
+KI+ ++ +K+L++ K+ QT+ E+ + E ++D++
Sbjct: 854 NLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQ 913
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
ES K L + E +++ + + +A+
Sbjct: 914 GAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLAR 973
Query: 844 VEVAFNKVKSLDAEI--QQHKKKNVPREM--EKIQEANDKLMEKQKQI--MTDRQV-LTK 896
+E + K L+ +I Q K V +E+ EK+Q+ K+ E + + + QV L K
Sbjct: 974 IETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQK-EQKIKEHATTVNELEELQVQLQK 1032
Query: 897 KIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL-NGINKEELNEKES 955
+ L+ + + E+ K+D + +I ++++ ELN+KL N NK E E+E
Sbjct: 1033 QKKQLQKTMQELELVKKDAQQTTLM---NMEIADYERLMKELNQKLTNKNNKIEDLEQEI 1089
Query: 956 LIIKQTKLFQQKAECTGALSELKK 979
I KQ + Q+ E T S +++
Sbjct: 1090 KIQKQKQETLQE-EITSLQSSVQQ 1112
Score = 41.9 bits (94), Expect = 0.013
Identities = 64/296 (21%), Positives = 118/296 (39%), Gaps = 26/296 (8%)
Query: 179 DEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEK 238
D + + + ++ L+K K+ + + ++ A VKAK KEL+ S K+ + +E E
Sbjct: 840 DPLSSVKELEEKIENLEKECKEKEEKINKIKLVA--VKAK-KELDSSRKETQTVKEELES 896
Query: 239 IANEK-----SSNEI----EYNKFILLESQNQ-EKIDKRNEQIVETAKIAEIENITEVQT 288
+ +EK S ++ E K +LLE + Q E++D E+ IE++T
Sbjct: 897 LRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEH--RIEDLTRQLR 954
Query: 289 N-----EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXX 343
N E + + +L ++E+L+S+ K+ + Q E ++ A+ VD+
Sbjct: 955 NSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQR-AKAMVDKELEAEKLQKEQKI 1013
Query: 344 XXXXXXXXXXXXXXXDITSANQSXXXXXXXXX-----XXXXXXXXHKQAENELNIEECQQ 398
+ + + A+ E ++E Q
Sbjct: 1014 KEHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQ 1073
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNK 454
++ +E EQE+ QK LQ++ L+ E TK KQL+V K
Sbjct: 1074 KLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKK 1129
Score = 36.7 bits (81), Expect = 0.50
Identities = 69/332 (20%), Positives = 134/332 (40%), Gaps = 33/332 (9%)
Query: 129 KDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEI----FDA 184
K++ R A+L IL+ + L S ++ N + +E + K+ KE+ ++I A
Sbjct: 815 KELRDRRAEL-ILLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVA 873
Query: 185 DKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKEL---EDSYKKNT-SFNKEEEKIA 240
K LD +K + + L+ L + + A ++L +SYK + K+ E++
Sbjct: 874 VKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLD 933
Query: 241 NEKS-SNEIEY----------NKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EK +N E+ N + E+ N + D R E + AK+ E++ I EVQ
Sbjct: 934 VEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQ-ILEVQ 992
Query: 288 TNEEA--ENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXX 345
+ + L+K + +K +H ++ +E + + Q + + +
Sbjct: 993 RAKAMVDKELEAEKLQKEQKIK-EHATTVNELEELQVQLQKQKKQLQKTMQELELVKKDA 1051
Query: 346 XXXXXXXXXXXXXD--ITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINED 403
+ + NQ KQ + L Q+EI
Sbjct: 1052 QQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETL-----QEEITSL 1106
Query: 404 EKAVEQYEQEMDELSQKITKLQKQTAKLKEKE 435
+ +V+QYE++ ++ Q + K +K+ A K+ E
Sbjct: 1107 QSSVQQYEEKNTKIKQLLVKTKKELADSKQAE 1138
Score = 35.5 bits (78), Expect = 1.2
Identities = 56/251 (22%), Positives = 129/251 (51%), Gaps = 28/251 (11%)
Query: 816 LKEKIE-AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQ 874
+K+++E + T++ +++L ++ Y+ ++E N++ ++ ++ + K N+ +++E+
Sbjct: 1 MKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKA-NLQKQLEEAM 59
Query: 875 EANDKLMEKQK-QIMTDRQV--LTKKIDTLKDEIAKQEVY-KRDLDDNLCLRKAQ-TDIT 929
+L E+ K Q ++ V L ++I+ ++ +Q +Y ++ LD +K T +
Sbjct: 60 NTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQ 119
Query: 930 N--------WQKQDDELNEKL---NGINKEELNEKESLIIKQTKLFQQKAECTGALSELK 978
N +QK + L E+L I++EE+ E I K + +AE L+ELK
Sbjct: 120 NIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAK--EHEAEIN-KLNELK 176
Query: 979 KSLKGFRNELEKSLSKDIEKKFREKMYELH-VTKAIDKDIREYAVALDK--CLMEFHREK 1035
++L + E S K+I+KK+ ++ L T ++D + ++ L + + + EK
Sbjct: 177 ENLV---KQCEAS-EKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEK 232
Query: 1036 MENINMIIREL 1046
++++ ++EL
Sbjct: 233 VKHLEDTLKEL 243
Score = 33.5 bits (73), Expect = 4.7
Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 8/138 (5%)
Query: 191 LDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSY-KKNTSFNKEEEKIANEKSSNEIE 249
+ L+ ++KD AQ L+ + KEL KN E++I +K E
Sbjct: 1041 MQELELVKKD-AQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETL 1099
Query: 250 YNKFILLES---QNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENAT-KTILEKVES 305
+ L+S Q +EK K + +V+T K E+ + + +T+ A+ K LE +
Sbjct: 1100 QEEITSLQSSVQQYEEKNTKIKQLLVKTKK--ELADSKQAETDHLILQASLKGELEASQQ 1157
Query: 306 LKSDHKVQKSQADEEEKK 323
+K+Q ++ E+ K
Sbjct: 1158 QVEVYKIQLAEITSEKHK 1175
>J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplakin
mRNA, 3' end. ).
Length = 1752
Score = 70.5 bits (165), Expect = 3e-11
Identities = 159/857 (18%), Positives = 345/857 (40%), Gaps = 85/857 (9%)
Query: 193 RLKKIRKDYAQNLKLLEN-YATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
R K+ RK +N Y KA+Q E K+N + K E + A ++ EIE
Sbjct: 1 REKRRRKSVEDRFDQQKNDYDQLQKARQCE-----KENLGWQKLESEKAIKEKEYEIERL 55
Query: 252 KFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHK 311
+ +LL+ + K + NE +A++ N NEE N ++ K+ K
Sbjct: 56 R-VLLQEEGTRKREYENE-------LAKVRN----HYNEEMSNLRNKYETEINITKTTIK 103
Query: 312 VQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXX 371
Q +++ K + +D + +A Q
Sbjct: 104 EISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGS 163
Query: 372 XXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL 431
K+ E+ +++ Q+ +ED +++Q ++E ++ I K+ +L
Sbjct: 164 EIM---------QKKQHLEIELKQVMQQRSEDNA---RHKQSLEEAAKTIQDKNKEIERL 211
Query: 432 KEKEMIEENLKTK-EKQLIVLKNKHKTALMELLGNVPEKDFAVT---INKFECEVRNEVX 487
K + E + + E +L ++N + ++ L N E + +T I++ + +
Sbjct: 212 KAEFQEEAKRRWEYENELSKVRNNYDEEIISLK-NQFETEINITKTTIHQLTMQKEEDTS 270
Query: 488 XXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTT 547
L E K ++ +L + L + E+ I + T +V+ K
Sbjct: 271 GYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGS-EVSQRKQQLE 329
Query: 548 VEKLQDEQNVLQSSMFIINKYKGQLKDNS-CCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
VE Q Q + S+ +YK L D + N+ E + +
Sbjct: 330 VELRQVTQMRTEESV----RYKQSLDDAAKTIQDKNKEIERLKQLIDKETNDRKCLEDEN 385
Query: 607 GKLEKVTEDLQRASAKKDEILS-MKSLNEKITTLK-DTEIPQLEKRIVDVDTQIKTLNET 664
+L++V DLQ+A++ E ++ +K +++T L+ D E E+ + D D I +
Sbjct: 386 ARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQD--ITRFQNS 443
Query: 665 VEEITMSLIEPEQKMTTAKQIHG-DMPMLDRYIQEIKTVTK--KFEAVKEQCGDVDSEMT 721
++E+ + + E+++ K+ D + +E++ + + K +A+K E
Sbjct: 444 LKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQA 503
Query: 722 LDVATAKQVDFKQKISTLRNRVKT---TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
V + D +Q+ L ++ TQ++L + +++ L + + +E + +
Sbjct: 504 SIVKKRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRN 563
Query: 779 QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE---AKTEVVRRNRDLIE 835
+ E K + ++ +T + L+E++ + + +RR R +
Sbjct: 564 EHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEAD 623
Query: 836 AG-SAYI----AKVEVAFNKVKSLDAEIQ--QHKKKNVPREMEKIQ----EANDKLMEKQ 884
+ +A I ++++++ N+ L I Q +++N+ +E+EK Q EA++++ E +
Sbjct: 624 SDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESK 683
Query: 885 KQ---IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT--------------- 926
Q ++ +R+ L KI L+ + A+ + + +L+ +A+T
Sbjct: 684 NQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQN 743
Query: 927 DITNWQKQDDELNEKLNGINKE-ELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFR 985
D+ W+ Q E + I E E +E+E ++ +++ + +AE ++ L+
Sbjct: 744 DLNQWKTQYSRKEEAIRKIESEREKSEREKNSLR-SEIERLQAEIKRIEERCRRKLEDST 802
Query: 986 NELEKSLSKDIEKKFRE 1002
E + L + + RE
Sbjct: 803 RETQSQLETERSRYQRE 819
Score = 48.8 bits (111), Expect = 1e-04
Identities = 134/754 (17%), Positives = 292/754 (38%), Gaps = 75/754 (9%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE 242
D+ + LDRL + +D + L + +++ E++ + + E I +
Sbjct: 112 DSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSE---IMQK 168
Query: 243 KSSNEIEYNKFILLESQNQEKIDKRNEQIVETA--KIAEIENIT-----EVQTNEEAENA 295
K EIE + + S++ + + E+ +T K EIE + E + E EN
Sbjct: 169 KQHLEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENE 228
Query: 296 TKTIL----EKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXX 351
+ E++ SLK+ + + + + +E SG+
Sbjct: 229 LSKVRNNYDEEIISLKNQFETEINITKTTIHQLTMQKEEDTSGYRAQIDNLTRENRSLSE 288
Query: 352 XXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYE 411
+T ++ Q + +L +E Q E++V +Y+
Sbjct: 289 EIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVELRQVTQMRTEESV-RYK 347
Query: 412 QEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDF 471
Q +D+ ++ I K+ +LK+ +I++ +T +++ + +N + L
Sbjct: 348 QSLDDAAKTIQDKNKEIERLKQ--LIDK--ETNDRKCLEDENARLQRVQYDLQKA-NSSA 402
Query: 472 AVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKA 531
TINK + + E+ + + + SL E + + K E+++ +
Sbjct: 403 TETINKLKVQ-EQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRL 461
Query: 532 CGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEX 591
T D K E+L+ + L+ I QL+ S + + E++
Sbjct: 462 KRTASEDSCKRKKLE--EELEGMRRSLKEQAIKITNLTQQLEQAS---IVKKRSEDDLRQ 516
Query: 592 XXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRI 651
+ ++ E+L+R S++ E L + L E+ ++K + E
Sbjct: 517 QRDVLDGHLR------EKQRTQEELRRLSSEV-EALRRQLLQEQ-ESVKQAHLRN-EHFQ 567
Query: 652 VDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
++ + ++LNE S IE E+ + + + + ML+ +E++ + +++ ++
Sbjct: 568 KAIEDKSRSLNE-------SKIEIERLQSLTENLTKEHLMLE---EELRNLRLEYDDLRR 617
Query: 712 QCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL 771
+ DS+ + ++ + ++ NR Q +N ++ + L ++ K +++
Sbjct: 618 GRSEADSDKNATI-----LELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQA 672
Query: 772 LNTQKKVQD-------IVNLEESK----KQLQSDCXXXXXXXXXXXXAITPLEVALKEKI 820
L ++Q+ +V ES K L+ D A + LE + K
Sbjct: 673 LEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQ 732
Query: 821 EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQ------ 874
+ E + DL + + Y K E A K++S + E + +K ++ E+E++Q
Sbjct: 733 RLECEKQQIQNDLNQWKTQYSRKEE-AIRKIES-EREKSEREKNSLRSEIERLQAEIKRI 790
Query: 875 ------EANDKLMEKQKQIMTDRQVLTKKIDTLK 902
+ D E Q Q+ T+R ++ID L+
Sbjct: 791 EERCRRKLEDSTRETQSQLETERSRYQREIDKLR 824
Score = 40.7 bits (91), Expect = 0.031
Identities = 71/391 (18%), Positives = 154/391 (39%), Gaps = 24/391 (6%)
Query: 153 LNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYA 212
+N + QE + +D + +ER + D ++ + L L+ ++ + L L+ A
Sbjct: 406 INKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLKELQLQKQKVEEELNRLKRTA 465
Query: 213 TTVKAKQKELEDSYK-KNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQI 271
+ K+K+LE+ + S ++ KI N + ++E + S++ D R ++
Sbjct: 466 SEDSCKRKKLEEELEGMRRSLKEQAIKITN--LTQQLEQASIVKKRSED----DLRQQRD 519
Query: 272 VETAKIAEIENITEV--QTNEEAENATKTILEKVESLKSDH----KVQKSQADEEEKKAQ 325
V + E + E + + E E + +L++ ES+K H QK+ D+ +
Sbjct: 520 VLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNE 579
Query: 326 GFVD-ECRSGHTQXXXXXXXXXXXXXXXXXXXXXDI---TSANQSXXXXXXXXXXXXXXX 381
++ E T+ D+ S S
Sbjct: 580 SKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQI 639
Query: 382 XXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQ-TAKLKEKEMIEEN 440
++ E + I + Q+E + +E+++++ E S +I + + Q T ++E+E +
Sbjct: 640 SNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVK 699
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE---VRNEVXXXXXXXXXXX 497
+K E+ L+ + + E + V + ECE ++N++
Sbjct: 700 IKVLEQDKARLQRLEDE--LNRAKSTLEAETRVK-QRLECEKQQIQNDLNQWKTQYSRKE 756
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAEDKI 528
+E+ER+ N RSE+ + + +I
Sbjct: 757 EAIRKIESEREKSEREKNSLRSEIERLQAEI 787
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 69.7 bits (163), Expect = 6e-11
Identities = 148/716 (20%), Positives = 293/716 (40%), Gaps = 58/716 (8%)
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
E+ + + DEL + + QK +LKE E L T+EK L+ + A EL
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLL---QEQLQAETELYAEAE 907
Query: 468 EKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK 527
E + K E E + L+AERK + + + + +L + E
Sbjct: 908 EMRVRLAAKKQELE--EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 528 IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFEN 587
K Q VT ++KL+DE V+ ++K + L++ N E
Sbjct: 966 RQK---LQLEKVTAE---AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
Query: 588 ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQL 647
E M + ++ L++ + E+ +K E + +I L
Sbjct: 1020 EKAKNLTKLKNKHESM-----ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
Query: 648 EKRIVDVDTQIKTLNETVEEITMSL-IEPEQKMTTAKQI---HGDMPMLDRYIQEIKTVT 703
+ +I ++ Q+ E ++ L E QK K+I G + L + +
Sbjct: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1134
Query: 704 KKFEAVKEQCGD------VDSEMTLD-VATAKQVDFK--QKISTLRNRVKTTQKKLNAHN 754
K E K G+ + E TLD AT +++ K Q+++ L+ K ++ +H
Sbjct: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK---KALDEETRSHE 1191
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAITPLE 813
++Q + +K +A EEL ++ + NL+++K+ L+ + A +E
Sbjct: 1192 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1251
Query: 814 VALKEKIEAKT-EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK------KKNV 866
K+K+EA+ E+ + D A + KV N+V+S+ + + + K+V
Sbjct: 1252 -HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 867 PREMEKIQEANDKLMEKQKQ---IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
++Q+ + L E+ +Q + T + L ++ ++L+D++ ++ K++L+ ++
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
Query: 924 AQTDITNWQKQD-DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
Q + + QD E L K E E+L T+ +++KA L + K L+
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL----TQQYEEKAAAYDKLEKTKNRLQ 1426
Query: 983 GFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHREKMENI 1039
++L L + + +K + A +K+I +YA D+ E REK
Sbjct: 1427 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE-AREKETKA 1485
Query: 1040 NMIIRELWRKIYRGNDID----YIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDM 1091
+ R L + +++ ++ + E ++ + + K + + +SK +E M
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Score = 60.1 bits (139), Expect = 5e-08
Identities = 149/738 (20%), Positives = 305/738 (41%), Gaps = 94/738 (12%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-KEKEM 436
K A+ L++EE ++ E+E A ++ + E KI KL+ Q KL KE+++
Sbjct: 947 KMAQQMLDLEE---QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1003
Query: 437 IEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEV 486
+EE + + K K L LKNKH++ + EL + +++ K E+
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE------KSRQELEKLK 1057
Query: 487 XXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTT 546
L+A+ ++ L ++ EL A ++ + + L K
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRE 1115
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
+ D Q L S NK + Q +D G E E+ +
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRD--------LGEELEA-----------LKTELE 1156
Query: 607 GKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L+ + + ++ E+ +K ++ T + ++ ++ ++ ++ L E +E
Sbjct: 1157 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA---VEELTEQLE 1213
Query: 667 EITMSLIE-PEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
+ + + K T K+ + G++ +L + QE++ KK EA Q ++ S+ +
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA---QVQELQSKCS- 1269
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
D A+ + K+ L+N V++ LN K L + +L +TQ+ +Q
Sbjct: 1270 DGERAR-AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ--- 1325
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE++++L L+ L E++EAK + R L S
Sbjct: 1326 --EETRQKLN-----VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 843 KVEVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
K++ + V++L+ ++ +K +N+ ++ E+ A DKL + + ++ + L +D
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+ ++ E +R D L K +I++ K DE + + E EKE+ +
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEK---NISS--KYADERDRA-----EAEAREKETKALSL 1488
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIRE 1019
+ ++ E L K LK +L S D+ K ++EL +K A++ + E
Sbjct: 1489 ARALEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGK----NVHELEKSKRALETQMEE 1543
Query: 1020 YAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYR 1079
L++ +E + E+ + + E+ + +G ++ + E N E +RR+ +
Sbjct: 1544 MKTQLEE--LEDELQATEDAKLRL-EVNMQALKGQFERDLQARDEQN---EEKRRQLQRQ 1597
Query: 1080 VVQSKNGVEIDMRGRCSA 1097
+ + + +E + + R A
Sbjct: 1598 LHEYETELEDERKQRALA 1615
Score = 60.1 bits (139), Expect = 5e-08
Identities = 171/933 (18%), Positives = 378/933 (40%), Gaps = 80/933 (8%)
Query: 173 KVKERFDEIFDADKYSDCLDRLKKIRK----DYAQNLKLLENYATTV-KAKQK------E 221
K+K+ DEI D ++ L + +K+ + D NL E A + K K K E
Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
Query: 222 LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFIL-LESQNQE---KIDKRNEQIVETAKI 277
LE KK +E EK+ + + ++++ I L++Q E ++ K+ E++ A +
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL--QAAL 1096
Query: 278 AEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
A +++ E+ A + + + L+ D +++ ++ EK+ + +E + T+
Sbjct: 1097 ARLDD--EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1154
Query: 338 XXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN--IEE 395
H QA EL +E+
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1214
Query: 396 CQQEINEDEKAVEQYEQEMDELSQKITKL----QKQTAKLKEKEMIEENLKTK----EKQ 447
++ +K + E+E +L+ ++ L Q+ K K+ E + L++K E+
Sbjct: 1215 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
Query: 448 LIVLKNK-HK--TALMELLGNVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L +K HK + + G + E + A+ + K + +++ +
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1334
Query: 504 EAERKHIRE---SLNERRSELTKAEDKIYKACGTQPYDVTLSK-----YTTTVEKLQDEQ 555
+ + + E SL ++ E +A+ + + T ++ SK + +TVE L++ +
Sbjct: 1335 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1394
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
Q I Q ++ + ++ + + ++ +
Sbjct: 1395 KRFQKE---IENLTQQYEEKAAA------YDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1445
Query: 616 LQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVEEIT-- 669
L++ K D++L+ K+++ K +D E + E + + + ++ E EE+
Sbjct: 1446 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505
Query: 670 --MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
M E E +++ + ++ L++ + ++T ++ + E+ D + + T D
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATEDAKLR 1564
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDIVNLEE 786
+V+ + ++ ++ ++LQ L+E +T+ ++E LE
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1624
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
K L+ + L+ +K+ + + E R +RD I A + K
Sbjct: 1625 DLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELEDARASRDEIFATAKENEK--- 1680
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKIDTLKDE 904
K KSL+A++ Q ++ E + Q +K L E+ ++ R L + L+
Sbjct: 1681 ---KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
Query: 905 IAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESLIIKQT 961
IA+ E +L++ +A +D + +Q ++L NE + + NE + +Q
Sbjct: 1738 IAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN 1794
Query: 962 KLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
K + K E GA+ S+ K ++ ++ + L + +E++ REK K DK ++E
Sbjct: 1795 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKDKKLKE 1853
Query: 1020 YAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
+ + ++ + E ++E+ E N +++L R++
Sbjct: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Score = 50.0 bits (114), Expect = 5e-05
Identities = 137/822 (16%), Positives = 316/822 (38%), Gaps = 62/822 (7%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKA 151
+ L+ R+ + A +K+ + L++ + +++ T D ++ +L +E+ V K
Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELED---TLDSTATQQELRAKREQEVTVLKK 1181
Query: 152 ILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC-LDR----LKKIRKDYAQNLK 206
L+ H+ + + E E + K + LD+ L+K D A L+
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1241
Query: 207 LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE------KSSNEIEYNKFILLESQN 260
+L V+ K+K+LE ++ S + E+ E K NE+E +L E++
Sbjct: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1301
Query: 261 QEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEE 320
+ I + ++++ + + + + +T ++ +TK + L+ + + Q DEE
Sbjct: 1302 KA-IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK-----LRQLEEERNSLQDQLDEE 1355
Query: 321 EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXX 380
+ Q + + Q +
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 1415
Query: 381 XXXHKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIE 438
K + +++ +++ + V E++ + Q + + + ++K E++ E
Sbjct: 1416 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1475
Query: 439 ENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXX 497
+ KE + + L AL E L E + + K E E + +
Sbjct: 1476 AEAREKETKALSLAR----ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1531
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAED-KIYKACGTQPYDVTLSK-YTTTVEKLQDEQ 555
LE + + ++ L E EL ED K+ Q + E+ ++++
Sbjct: 1532 KSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1591
Query: 556 NVLQSSMFIIN-KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX----XMNVPGKLE 610
LQ + + + + K + + E + + + KL+
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 611 KVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+D QR A A +DEI + NEK + ++ QL++ + + K + E
Sbjct: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVA 725
E+ L A + G + D + + + E ++E+ G++++ + A
Sbjct: 1712 ELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 726 TAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
T + +++T R+ + ++ +++L NK+L++ L+E + K + +T I
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST------I 1816
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGS 838
LE QL+ ++ + LKE ++E + ++ + ++ E G+
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 1917
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 69.7 bits (163), Expect = 6e-11
Identities = 148/716 (20%), Positives = 293/716 (40%), Gaps = 58/716 (8%)
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
E+ + + DEL + + QK +LKE E L T+EK L+ + A EL
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLL---QEQLQAETELYAEAE 907
Query: 468 EKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK 527
E + K E E + L+AERK + + + + +L + E
Sbjct: 908 EMRVRLAAKKQELE--EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 965
Query: 528 IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFEN 587
K Q VT ++KL+DE V+ ++K + L++ N E
Sbjct: 966 RQK---LQLEKVTAE---AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1019
Query: 588 ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQL 647
E M + ++ L++ + E+ +K E + +I L
Sbjct: 1020 EKAKNLTKLKNKHESM-----ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
Query: 648 EKRIVDVDTQIKTLNETVEEITMSL-IEPEQKMTTAKQI---HGDMPMLDRYIQEIKTVT 703
+ +I ++ Q+ E ++ L E QK K+I G + L + +
Sbjct: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1134
Query: 704 KKFEAVKEQCGD------VDSEMTLD-VATAKQVDFK--QKISTLRNRVKTTQKKLNAHN 754
K E K G+ + E TLD AT +++ K Q+++ L+ K ++ +H
Sbjct: 1135 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK---KALDEETRSHE 1191
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAITPLE 813
++Q + +K +A EEL ++ + NL+++K+ L+ + A +E
Sbjct: 1192 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1251
Query: 814 VALKEKIEAKT-EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK------KKNV 866
K+K+EA+ E+ + D A + KV N+V+S+ + + + K+V
Sbjct: 1252 -HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1310
Query: 867 PREMEKIQEANDKLMEKQKQ---IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
++Q+ + L E+ +Q + T + L ++ ++L+D++ ++ K++L+ ++
Sbjct: 1311 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1370
Query: 924 AQTDITNWQKQD-DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
Q + + QD E L K E E+L T+ +++KA L + K L+
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL----TQQYEEKAAAYDKLEKTKNRLQ 1426
Query: 983 GFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHREKMENI 1039
++L L + + +K + A +K+I +YA D+ E REK
Sbjct: 1427 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE-AREKETKA 1485
Query: 1040 NMIIRELWRKIYRGNDID----YIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDM 1091
+ R L + +++ ++ + E ++ + + K + + +SK +E M
Sbjct: 1486 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1541
Score = 60.1 bits (139), Expect = 5e-08
Identities = 149/738 (20%), Positives = 305/738 (41%), Gaps = 94/738 (12%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-KEKEM 436
K A+ L++EE ++ E+E A ++ + E KI KL+ Q KL KE+++
Sbjct: 947 KMAQQMLDLEE---QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1003
Query: 437 IEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEV 486
+EE + + K K L LKNKH++ + EL + +++ K E+
Sbjct: 1004 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE------KSRQELEKLK 1057
Query: 487 XXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTT 546
L+A+ ++ L ++ EL A ++ + + L K
Sbjct: 1058 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRE 1115
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
+ D Q L S NK + Q +D G E E+ +
Sbjct: 1116 LEGHISDLQEDLDSERAARNKAEKQKRD--------LGEELEA-----------LKTELE 1156
Query: 607 GKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L+ + + ++ E+ +K ++ T + ++ ++ ++ ++ L E +E
Sbjct: 1157 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA---VEELTEQLE 1213
Query: 667 EITMSLIE-PEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
+ + + K T K+ + G++ +L + QE++ KK EA Q ++ S+ +
Sbjct: 1214 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA---QVQELQSKCS- 1269
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
D A+ + K+ L+N V++ LN K L + +L +TQ+ +Q
Sbjct: 1270 DGERAR-AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ--- 1325
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE++++L L+ L E++EAK + R L S
Sbjct: 1326 --EETRQKLN-----VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1378
Query: 843 KVEVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
K++ + V++L+ ++ +K +N+ ++ E+ A DKL + + ++ + L +D
Sbjct: 1379 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+ ++ E +R D L K +I++ K DE + + E EKE+ +
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEK---NISS--KYADERDRA-----EAEAREKETKALSL 1488
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIRE 1019
+ ++ E L K LK +L S D+ K ++EL +K A++ + E
Sbjct: 1489 ARALEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGK----NVHELEKSKRALETQMEE 1543
Query: 1020 YAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYR 1079
L++ +E + E+ + + E+ + +G ++ + E N E +RR+ +
Sbjct: 1544 MKTQLEE--LEDELQATEDAKLRL-EVNMQALKGQFERDLQARDEQN---EEKRRQLQRQ 1597
Query: 1080 VVQSKNGVEIDMRGRCSA 1097
+ + + +E + + R A
Sbjct: 1598 LHEYETELEDERKQRALA 1615
Score = 60.1 bits (139), Expect = 5e-08
Identities = 171/933 (18%), Positives = 378/933 (40%), Gaps = 80/933 (8%)
Query: 173 KVKERFDEIFDADKYSDCLDRLKKIRK----DYAQNLKLLENYATTV-KAKQK------E 221
K+K+ DEI D ++ L + +K+ + D NL E A + K K K E
Sbjct: 979 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1038
Query: 222 LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFIL-LESQNQE---KIDKRNEQIVETAKI 277
LE KK +E EK+ + + ++++ I L++Q E ++ K+ E++ A +
Sbjct: 1039 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL--QAAL 1096
Query: 278 AEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
A +++ E+ A + + + L+ D +++ ++ EK+ + +E + T+
Sbjct: 1097 ARLDD--EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1154
Query: 338 XXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN--IEE 395
H QA EL +E+
Sbjct: 1155 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1214
Query: 396 CQQEINEDEKAVEQYEQEMDELSQKITKL----QKQTAKLKEKEMIEENLKTK----EKQ 447
++ +K + E+E +L+ ++ L Q+ K K+ E + L++K E+
Sbjct: 1215 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1274
Query: 448 LIVLKNK-HK--TALMELLGNVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L +K HK + + G + E + A+ + K + +++ +
Sbjct: 1275 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1334
Query: 504 EAERKHIRE---SLNERRSELTKAEDKIYKACGTQPYDVTLSK-----YTTTVEKLQDEQ 555
+ + + E SL ++ E +A+ + + T ++ SK + +TVE L++ +
Sbjct: 1335 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1394
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
Q I Q ++ + ++ + + ++ +
Sbjct: 1395 KRFQKE---IENLTQQYEEKAAA------YDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1445
Query: 616 LQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVEEIT-- 669
L++ K D++L+ K+++ K +D E + E + + + ++ E EE+
Sbjct: 1446 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505
Query: 670 --MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
M E E +++ + ++ L++ + ++T ++ + E+ D + + T D
Sbjct: 1506 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATEDAKLR 1564
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDIVNLEE 786
+V+ + ++ ++ ++LQ L+E +T+ ++E LE
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1624
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
K L+ + L+ +K+ + + E R +RD I A + K
Sbjct: 1625 DLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELEDARASRDEIFATAKENEK--- 1680
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKIDTLKDE 904
K KSL+A++ Q ++ E + Q +K L E+ ++ R L + L+
Sbjct: 1681 ---KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1737
Query: 905 IAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESLIIKQT 961
IA+ E +L++ +A +D + +Q ++L NE + + NE + +Q
Sbjct: 1738 IAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN 1794
Query: 962 KLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
K + K E GA+ S+ K ++ ++ + L + +E++ REK K DK ++E
Sbjct: 1795 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKDKKLKE 1853
Query: 1020 YAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
+ + ++ + E ++E+ E N +++L R++
Sbjct: 1854 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1886
Score = 50.0 bits (114), Expect = 5e-05
Identities = 137/822 (16%), Positives = 316/822 (38%), Gaps = 62/822 (7%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKA 151
+ L+ R+ + A +K+ + L++ + +++ T D ++ +L +E+ V K
Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELED---TLDSTATQQELRAKREQEVTVLKK 1181
Query: 152 ILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC-LDR----LKKIRKDYAQNLK 206
L+ H+ + + E E + K + LD+ L+K D A L+
Sbjct: 1182 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1241
Query: 207 LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE------KSSNEIEYNKFILLESQN 260
+L V+ K+K+LE ++ S + E+ E K NE+E +L E++
Sbjct: 1242 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1301
Query: 261 QEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEE 320
+ I + ++++ + + + + +T ++ +TK + L+ + + Q DEE
Sbjct: 1302 KA-IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK-----LRQLEEERNSLQDQLDEE 1355
Query: 321 EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXX 380
+ Q + + Q +
Sbjct: 1356 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 1415
Query: 381 XXXHKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIE 438
K + +++ +++ + V E++ + Q + + + ++K E++ E
Sbjct: 1416 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1475
Query: 439 ENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXX 497
+ KE + + L AL E L E + + K E E + +
Sbjct: 1476 AEAREKETKALSLAR----ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1531
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAED-KIYKACGTQPYDVTLSK-YTTTVEKLQDEQ 555
LE + + ++ L E EL ED K+ Q + E+ ++++
Sbjct: 1532 KSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1591
Query: 556 NVLQSSMFIIN-KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX----XMNVPGKLE 610
LQ + + + + K + + E + + + KL+
Sbjct: 1592 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1651
Query: 611 KVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+D QR A A +DEI + NEK + ++ QL++ + + K + E
Sbjct: 1652 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1711
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVA 725
E+ L A + G + D + + + E ++E+ G++++ + A
Sbjct: 1712 ELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 726 TAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
T + +++T R+ + ++ +++L NK+L++ L+E + K + +T I
Sbjct: 1763 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST------I 1816
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGS 838
LE QL+ ++ + LKE ++E + ++ + ++ E G+
Sbjct: 1817 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1876
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 1877 ARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 1917
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 69.7 bits (163), Expect = 6e-11
Identities = 148/716 (20%), Positives = 293/716 (40%), Gaps = 58/716 (8%)
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
E+ + + DEL + + QK +LKE E L T+EK L+ + A EL
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLL---QEQLQAETELYAEAE 914
Query: 468 EKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK 527
E + K E E + L+AERK + + + + +L + E
Sbjct: 915 EMRVRLAAKKQELE--EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 528 IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFEN 587
K Q VT ++KL+DE V+ ++K + L++ N E
Sbjct: 973 RQK---LQLEKVTAE---AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1026
Query: 588 ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQL 647
E M + ++ L++ + E+ +K E + +I L
Sbjct: 1027 EKAKNLTKLKNKHESM-----ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1081
Query: 648 EKRIVDVDTQIKTLNETVEEITMSL-IEPEQKMTTAKQI---HGDMPMLDRYIQEIKTVT 703
+ +I ++ Q+ E ++ L E QK K+I G + L + +
Sbjct: 1082 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1141
Query: 704 KKFEAVKEQCGD------VDSEMTLD-VATAKQVDFK--QKISTLRNRVKTTQKKLNAHN 754
K E K G+ + E TLD AT +++ K Q+++ L+ K ++ +H
Sbjct: 1142 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK---KALDEETRSHE 1198
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAITPLE 813
++Q + +K +A EEL ++ + NL+++K+ L+ + A +E
Sbjct: 1199 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1258
Query: 814 VALKEKIEAKT-EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK------KKNV 866
K+K+EA+ E+ + D A + KV N+V+S+ + + + K+V
Sbjct: 1259 -HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 867 PREMEKIQEANDKLMEKQKQ---IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
++Q+ + L E+ +Q + T + L ++ ++L+D++ ++ K++L+ ++
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377
Query: 924 AQTDITNWQKQD-DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
Q + + QD E L K E E+L T+ +++KA L + K L+
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL----TQQYEEKAAAYDKLEKTKNRLQ 1433
Query: 983 GFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHREKMENI 1039
++L L + + +K + A +K+I +YA D+ E REK
Sbjct: 1434 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE-AREKETKA 1492
Query: 1040 NMIIRELWRKIYRGNDID----YIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDM 1091
+ R L + +++ ++ + E ++ + + K + + +SK +E M
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Score = 60.1 bits (139), Expect = 5e-08
Identities = 149/738 (20%), Positives = 305/738 (41%), Gaps = 94/738 (12%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-KEKEM 436
K A+ L++EE ++ E+E A ++ + E KI KL+ Q KL KE+++
Sbjct: 954 KMAQQMLDLEE---QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1010
Query: 437 IEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEV 486
+EE + + K K L LKNKH++ + EL + +++ K E+
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE------KSRQELEKLK 1064
Query: 487 XXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTT 546
L+A+ ++ L ++ EL A ++ + + L K
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRE 1122
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
+ D Q L S NK + Q +D G E E+ +
Sbjct: 1123 LEGHISDLQEDLDSERAARNKAEKQKRD--------LGEELEA-----------LKTELE 1163
Query: 607 GKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L+ + + ++ E+ +K ++ T + ++ ++ ++ ++ L E +E
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA---VEELTEQLE 1220
Query: 667 EITMSLIE-PEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
+ + + K T K+ + G++ +L + QE++ KK EA Q ++ S+ +
Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA---QVQELQSKCS- 1276
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
D A+ + K+ L+N V++ LN K L + +L +TQ+ +Q
Sbjct: 1277 DGERAR-AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ--- 1332
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE++++L L+ L E++EAK + R L S
Sbjct: 1333 --EETRQKLN-----VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 843 KVEVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
K++ + V++L+ ++ +K +N+ ++ E+ A DKL + + ++ + L +D
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+ ++ E +R D L K +I++ K DE + + E EKE+ +
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEK---NISS--KYADERDRA-----EAEAREKETKALSL 1495
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIRE 1019
+ ++ E L K LK +L S D+ K ++EL +K A++ + E
Sbjct: 1496 ARALEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGK----NVHELEKSKRALETQMEE 1550
Query: 1020 YAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYR 1079
L++ +E + E+ + + E+ + +G ++ + E N E +RR+ +
Sbjct: 1551 MKTQLEE--LEDELQATEDAKLRL-EVNMQALKGQFERDLQARDEQN---EEKRRQLQRQ 1604
Query: 1080 VVQSKNGVEIDMRGRCSA 1097
+ + + +E + + R A
Sbjct: 1605 LHEYETELEDERKQRALA 1622
Score = 60.1 bits (139), Expect = 5e-08
Identities = 171/933 (18%), Positives = 378/933 (40%), Gaps = 80/933 (8%)
Query: 173 KVKERFDEIFDADKYSDCLDRLKKIRK----DYAQNLKLLENYATTV-KAKQK------E 221
K+K+ DEI D ++ L + +K+ + D NL E A + K K K E
Sbjct: 986 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045
Query: 222 LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFIL-LESQNQE---KIDKRNEQIVETAKI 277
LE KK +E EK+ + + ++++ I L++Q E ++ K+ E++ A +
Sbjct: 1046 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL--QAAL 1103
Query: 278 AEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
A +++ E+ A + + + L+ D +++ ++ EK+ + +E + T+
Sbjct: 1104 ARLDD--EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1161
Query: 338 XXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN--IEE 395
H QA EL +E+
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1221
Query: 396 CQQEINEDEKAVEQYEQEMDELSQKITKL----QKQTAKLKEKEMIEENLKTK----EKQ 447
++ +K + E+E +L+ ++ L Q+ K K+ E + L++K E+
Sbjct: 1222 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1281
Query: 448 LIVLKNK-HK--TALMELLGNVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L +K HK + + G + E + A+ + K + +++ +
Sbjct: 1282 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1341
Query: 504 EAERKHIRE---SLNERRSELTKAEDKIYKACGTQPYDVTLSK-----YTTTVEKLQDEQ 555
+ + + E SL ++ E +A+ + + T ++ SK + +TVE L++ +
Sbjct: 1342 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1401
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
Q I Q ++ + ++ + + ++ +
Sbjct: 1402 KRFQKE---IENLTQQYEEKAAA------YDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1452
Query: 616 LQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVEEIT-- 669
L++ K D++L+ K+++ K +D E + E + + + ++ E EE+
Sbjct: 1453 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1512
Query: 670 --MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
M E E +++ + ++ L++ + ++T ++ + E+ D + + T D
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATEDAKLR 1571
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDIVNLEE 786
+V+ + ++ ++ ++LQ L+E +T+ ++E LE
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1631
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
K L+ + L+ +K+ + + E R +RD I A + K
Sbjct: 1632 DLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELEDARASRDEIFATAKENEK--- 1687
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKIDTLKDE 904
K KSL+A++ Q ++ E + Q +K L E+ ++ R L + L+
Sbjct: 1688 ---KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1744
Query: 905 IAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESLIIKQT 961
IA+ E +L++ +A +D + +Q ++L NE + + NE + +Q
Sbjct: 1745 IAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN 1801
Query: 962 KLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
K + K E GA+ S+ K ++ ++ + L + +E++ REK K DK ++E
Sbjct: 1802 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKDKKLKE 1860
Query: 1020 YAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
+ + ++ + E ++E+ E N +++L R++
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Score = 50.0 bits (114), Expect = 5e-05
Identities = 137/822 (16%), Positives = 316/822 (38%), Gaps = 62/822 (7%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKA 151
+ L+ R+ + A +K+ + L++ + +++ T D ++ +L +E+ V K
Sbjct: 1132 EDLDSERAARNKAEKQKRDLGEELEALKTELED---TLDSTATQQELRAKREQEVTVLKK 1188
Query: 152 ILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC-LDR----LKKIRKDYAQNLK 206
L+ H+ + + E E + K + LD+ L+K D A L+
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1248
Query: 207 LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE------KSSNEIEYNKFILLESQN 260
+L V+ K+K+LE ++ S + E+ E K NE+E +L E++
Sbjct: 1249 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1308
Query: 261 QEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEE 320
+ I + ++++ + + + + +T ++ +TK + L+ + + Q DEE
Sbjct: 1309 KA-IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK-----LRQLEEERNSLQDQLDEE 1362
Query: 321 EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXX 380
+ Q + + Q +
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 1422
Query: 381 XXXHKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIE 438
K + +++ +++ + V E++ + Q + + + ++K E++ E
Sbjct: 1423 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1482
Query: 439 ENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXX 497
+ KE + + L AL E L E + + K E E + +
Sbjct: 1483 AEAREKETKALSLAR----ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1538
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAED-KIYKACGTQPYDVTLSK-YTTTVEKLQDEQ 555
LE + + ++ L E EL ED K+ Q + E+ ++++
Sbjct: 1539 KSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1598
Query: 556 NVLQSSMFIIN-KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX----XMNVPGKLE 610
LQ + + + + K + + E + + + KL+
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 611 KVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+D QR A A +DEI + NEK + ++ QL++ + + K + E
Sbjct: 1659 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVA 725
E+ L A + G + D + + + E ++E+ G++++ + A
Sbjct: 1719 ELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 726 TAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
T + +++T R+ + ++ +++L NK+L++ L+E + K + +T I
Sbjct: 1770 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST------I 1823
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGS 838
LE QL+ ++ + LKE ++E + ++ + ++ E G+
Sbjct: 1824 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 1924
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 69.7 bits (163), Expect = 6e-11
Identities = 148/716 (20%), Positives = 293/716 (40%), Gaps = 58/716 (8%)
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
E+ + + DEL + + QK +LKE E L T+EK L+ + A EL
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLL---QEQLQAETELYAEAE 914
Query: 468 EKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK 527
E + K E E + L+AERK + + + + +L + E
Sbjct: 915 EMRVRLAAKKQELE--EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 972
Query: 528 IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFEN 587
K Q VT ++KL+DE V+ ++K + L++ N E
Sbjct: 973 RQK---LQLEKVTAE---AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1026
Query: 588 ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQL 647
E M + ++ L++ + E+ +K E + +I L
Sbjct: 1027 EKAKNLTKLKNKHESM-----ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1081
Query: 648 EKRIVDVDTQIKTLNETVEEITMSL-IEPEQKMTTAKQI---HGDMPMLDRYIQEIKTVT 703
+ +I ++ Q+ E ++ L E QK K+I G + L + +
Sbjct: 1082 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1141
Query: 704 KKFEAVKEQCGD------VDSEMTLD-VATAKQVDFK--QKISTLRNRVKTTQKKLNAHN 754
K E K G+ + E TLD AT +++ K Q+++ L+ K ++ +H
Sbjct: 1142 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK---KALDEETRSHE 1198
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAITPLE 813
++Q + +K +A EEL ++ + NL+++K+ L+ + A +E
Sbjct: 1199 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1258
Query: 814 VALKEKIEAKT-EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK------KKNV 866
K+K+EA+ E+ + D A + KV N+V+S+ + + + K+V
Sbjct: 1259 -HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1317
Query: 867 PREMEKIQEANDKLMEKQKQ---IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
++Q+ + L E+ +Q + T + L ++ ++L+D++ ++ K++L+ ++
Sbjct: 1318 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1377
Query: 924 AQTDITNWQKQD-DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
Q + + QD E L K E E+L T+ +++KA L + K L+
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL----TQQYEEKAAAYDKLEKTKNRLQ 1433
Query: 983 GFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHREKMENI 1039
++L L + + +K + A +K+I +YA D+ E REK
Sbjct: 1434 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE-AREKETKA 1492
Query: 1040 NMIIRELWRKIYRGNDID----YIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDM 1091
+ R L + +++ ++ + E ++ + + K + + +SK +E M
Sbjct: 1493 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1548
Score = 60.1 bits (139), Expect = 5e-08
Identities = 149/738 (20%), Positives = 305/738 (41%), Gaps = 94/738 (12%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-KEKEM 436
K A+ L++EE ++ E+E A ++ + E KI KL+ Q KL KE+++
Sbjct: 954 KMAQQMLDLEE---QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1010
Query: 437 IEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEV 486
+EE + + K K L LKNKH++ + EL + +++ K E+
Sbjct: 1011 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE------KSRQELEKLK 1064
Query: 487 XXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTT 546
L+A+ ++ L ++ EL A ++ + + L K
Sbjct: 1065 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRE 1122
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
+ D Q L S NK + Q +D G E E+ +
Sbjct: 1123 LEGHISDLQEDLDSERAARNKAEKQKRD--------LGEELEA-----------LKTELE 1163
Query: 607 GKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L+ + + ++ E+ +K ++ T + ++ ++ ++ ++ L E +E
Sbjct: 1164 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA---VEELTEQLE 1220
Query: 667 EITMSLIE-PEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
+ + + K T K+ + G++ +L + QE++ KK EA Q ++ S+ +
Sbjct: 1221 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA---QVQELQSKCS- 1276
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
D A+ + K+ L+N V++ LN K L + +L +TQ+ +Q
Sbjct: 1277 DGERAR-AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ--- 1332
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE++++L L+ L E++EAK + R L S
Sbjct: 1333 --EETRQKLN-----VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1385
Query: 843 KVEVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
K++ + V++L+ ++ +K +N+ ++ E+ A DKL + + ++ + L +D
Sbjct: 1386 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+ ++ E +R D L K +I++ K DE + + E EKE+ +
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEK---NISS--KYADERDRA-----EAEAREKETKALSL 1495
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIRE 1019
+ ++ E L K LK +L S D+ K ++EL +K A++ + E
Sbjct: 1496 ARALEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGK----NVHELEKSKRALETQMEE 1550
Query: 1020 YAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYR 1079
L++ +E + E+ + + E+ + +G ++ + E N E +RR+ +
Sbjct: 1551 MKTQLEE--LEDELQATEDAKLRL-EVNMQALKGQFERDLQARDEQN---EEKRRQLQRQ 1604
Query: 1080 VVQSKNGVEIDMRGRCSA 1097
+ + + +E + + R A
Sbjct: 1605 LHEYETELEDERKQRALA 1622
Score = 60.1 bits (139), Expect = 5e-08
Identities = 171/933 (18%), Positives = 378/933 (40%), Gaps = 80/933 (8%)
Query: 173 KVKERFDEIFDADKYSDCLDRLKKIRK----DYAQNLKLLENYATTV-KAKQK------E 221
K+K+ DEI D ++ L + +K+ + D NL E A + K K K E
Sbjct: 986 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1045
Query: 222 LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFIL-LESQNQE---KIDKRNEQIVETAKI 277
LE KK +E EK+ + + ++++ I L++Q E ++ K+ E++ A +
Sbjct: 1046 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL--QAAL 1103
Query: 278 AEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
A +++ E+ A + + + L+ D +++ ++ EK+ + +E + T+
Sbjct: 1104 ARLDD--EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1161
Query: 338 XXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN--IEE 395
H QA EL +E+
Sbjct: 1162 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1221
Query: 396 CQQEINEDEKAVEQYEQEMDELSQKITKL----QKQTAKLKEKEMIEENLKTK----EKQ 447
++ +K + E+E +L+ ++ L Q+ K K+ E + L++K E+
Sbjct: 1222 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1281
Query: 448 LIVLKNK-HK--TALMELLGNVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L +K HK + + G + E + A+ + K + +++ +
Sbjct: 1282 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1341
Query: 504 EAERKHIRE---SLNERRSELTKAEDKIYKACGTQPYDVTLSK-----YTTTVEKLQDEQ 555
+ + + E SL ++ E +A+ + + T ++ SK + +TVE L++ +
Sbjct: 1342 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1401
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
Q I Q ++ + ++ + + ++ +
Sbjct: 1402 KRFQKE---IENLTQQYEEKAAA------YDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1452
Query: 616 LQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVEEIT-- 669
L++ K D++L+ K+++ K +D E + E + + + ++ E EE+
Sbjct: 1453 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1512
Query: 670 --MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
M E E +++ + ++ L++ + ++T ++ + E+ D + + T D
Sbjct: 1513 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATEDAKLR 1571
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDIVNLEE 786
+V+ + ++ ++ ++LQ L+E +T+ ++E LE
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1631
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
K L+ + L+ +K+ + + E R +RD I A + K
Sbjct: 1632 DLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELEDARASRDEIFATAKENEK--- 1687
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKIDTLKDE 904
K KSL+A++ Q ++ E + Q +K L E+ ++ R L + L+
Sbjct: 1688 ---KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1744
Query: 905 IAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESLIIKQT 961
IA+ E +L++ +A +D + +Q ++L NE + + NE + +Q
Sbjct: 1745 IAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN 1801
Query: 962 KLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
K + K E GA+ S+ K ++ ++ + L + +E++ REK K DK ++E
Sbjct: 1802 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKDKKLKE 1860
Query: 1020 YAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
+ + ++ + E ++E+ E N +++L R++
Sbjct: 1861 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1893
Score = 50.0 bits (114), Expect = 5e-05
Identities = 137/822 (16%), Positives = 316/822 (38%), Gaps = 62/822 (7%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKA 151
+ L+ R+ + A +K+ + L++ + +++ T D ++ +L +E+ V K
Sbjct: 1132 EDLDSERAARNKAEKQKRDLGEELEALKTELED---TLDSTATQQELRAKREQEVTVLKK 1188
Query: 152 ILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC-LDR----LKKIRKDYAQNLK 206
L+ H+ + + E E + K + LD+ L+K D A L+
Sbjct: 1189 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1248
Query: 207 LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE------KSSNEIEYNKFILLESQN 260
+L V+ K+K+LE ++ S + E+ E K NE+E +L E++
Sbjct: 1249 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1308
Query: 261 QEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEE 320
+ I + ++++ + + + + +T ++ +TK + L+ + + Q DEE
Sbjct: 1309 KA-IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK-----LRQLEEERNSLQDQLDEE 1362
Query: 321 EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXX 380
+ Q + + Q +
Sbjct: 1363 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 1422
Query: 381 XXXHKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIE 438
K + +++ +++ + V E++ + Q + + + ++K E++ E
Sbjct: 1423 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1482
Query: 439 ENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXX 497
+ KE + + L AL E L E + + K E E + +
Sbjct: 1483 AEAREKETKALSLAR----ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1538
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAED-KIYKACGTQPYDVTLSK-YTTTVEKLQDEQ 555
LE + + ++ L E EL ED K+ Q + E+ ++++
Sbjct: 1539 KSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1598
Query: 556 NVLQSSMFIIN-KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX----XMNVPGKLE 610
LQ + + + + K + + E + + + KL+
Sbjct: 1599 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1658
Query: 611 KVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+D QR A A +DEI + NEK + ++ QL++ + + K + E
Sbjct: 1659 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1718
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVA 725
E+ L A + G + D + + + E ++E+ G++++ + A
Sbjct: 1719 ELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 726 TAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
T + +++T R+ + ++ +++L NK+L++ L+E + K + +T I
Sbjct: 1770 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST------I 1823
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGS 838
LE QL+ ++ + LKE ++E + ++ + ++ E G+
Sbjct: 1824 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1883
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 1884 ARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 1924
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 69.7 bits (163), Expect = 6e-11
Identities = 148/716 (20%), Positives = 293/716 (40%), Gaps = 58/716 (8%)
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
E+ + + DEL + + QK +LKE E L T+EK L+ + A EL
Sbjct: 737 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLL---QEQLQAETELYAEAE 792
Query: 468 EKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK 527
E + K E E + L+AERK + + + + +L + E
Sbjct: 793 EMRVRLAAKKQELE--EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 850
Query: 528 IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFEN 587
K Q VT ++KL+DE V+ ++K + L++ N E
Sbjct: 851 RQK---LQLEKVTAE---AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 904
Query: 588 ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQL 647
E M + ++ L++ + E+ +K E + +I L
Sbjct: 905 EKAKNLTKLKNKHESM-----ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 959
Query: 648 EKRIVDVDTQIKTLNETVEEITMSL-IEPEQKMTTAKQI---HGDMPMLDRYIQEIKTVT 703
+ +I ++ Q+ E ++ L E QK K+I G + L + +
Sbjct: 960 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1019
Query: 704 KKFEAVKEQCGD------VDSEMTLD-VATAKQVDFK--QKISTLRNRVKTTQKKLNAHN 754
K E K G+ + E TLD AT +++ K Q+++ L+ K ++ +H
Sbjct: 1020 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK---KALDEETRSHE 1076
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAITPLE 813
++Q + +K +A EEL ++ + NL+++K+ L+ + A +E
Sbjct: 1077 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1136
Query: 814 VALKEKIEAKT-EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK------KKNV 866
K+K+EA+ E+ + D A + KV N+V+S+ + + + K+V
Sbjct: 1137 -HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1195
Query: 867 PREMEKIQEANDKLMEKQKQ---IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
++Q+ + L E+ +Q + T + L ++ ++L+D++ ++ K++L+ ++
Sbjct: 1196 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1255
Query: 924 AQTDITNWQKQD-DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
Q + + QD E L K E E+L T+ +++KA L + K L+
Sbjct: 1256 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL----TQQYEEKAAAYDKLEKTKNRLQ 1311
Query: 983 GFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHREKMENI 1039
++L L + + +K + A +K+I +YA D+ E REK
Sbjct: 1312 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE-AREKETKA 1370
Query: 1040 NMIIRELWRKIYRGNDID----YIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDM 1091
+ R L + +++ ++ + E ++ + + K + + +SK +E M
Sbjct: 1371 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1426
Score = 60.1 bits (139), Expect = 5e-08
Identities = 149/738 (20%), Positives = 305/738 (41%), Gaps = 94/738 (12%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-KEKEM 436
K A+ L++EE ++ E+E A ++ + E KI KL+ Q KL KE+++
Sbjct: 832 KMAQQMLDLEE---QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 888
Query: 437 IEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEV 486
+EE + + K K L LKNKH++ + EL + +++ K E+
Sbjct: 889 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE------KSRQELEKLK 942
Query: 487 XXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTT 546
L+A+ ++ L ++ EL A ++ + + L K
Sbjct: 943 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRE 1000
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
+ D Q L S NK + Q +D G E E+ +
Sbjct: 1001 LEGHISDLQEDLDSERAARNKAEKQKRD--------LGEELEA-----------LKTELE 1041
Query: 607 GKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L+ + + ++ E+ +K ++ T + ++ ++ ++ ++ L E +E
Sbjct: 1042 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA---VEELTEQLE 1098
Query: 667 EITMSLIE-PEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
+ + + K T K+ + G++ +L + QE++ KK EA Q ++ S+ +
Sbjct: 1099 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA---QVQELQSKCS- 1154
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
D A+ + K+ L+N V++ LN K L + +L +TQ+ +Q
Sbjct: 1155 DGERAR-AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ--- 1210
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE++++L L+ L E++EAK + R L S
Sbjct: 1211 --EETRQKLN-----VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1263
Query: 843 KVEVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
K++ + V++L+ ++ +K +N+ ++ E+ A DKL + + ++ + L +D
Sbjct: 1264 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1323
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+ ++ E +R D L K +I++ K DE + + E EKE+ +
Sbjct: 1324 QRQLVSNLEKKQRKFDQLLAEEK---NISS--KYADERDRA-----EAEAREKETKALSL 1373
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIRE 1019
+ ++ E L K LK +L S D+ K ++EL +K A++ + E
Sbjct: 1374 ARALEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGK----NVHELEKSKRALETQMEE 1428
Query: 1020 YAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYR 1079
L++ +E + E+ + + E+ + +G ++ + E N E +RR+ +
Sbjct: 1429 MKTQLEE--LEDELQATEDAKLRL-EVNMQALKGQFERDLQARDEQN---EEKRRQLQRQ 1482
Query: 1080 VVQSKNGVEIDMRGRCSA 1097
+ + + +E + + R A
Sbjct: 1483 LHEYETELEDERKQRALA 1500
Score = 60.1 bits (139), Expect = 5e-08
Identities = 171/933 (18%), Positives = 378/933 (40%), Gaps = 80/933 (8%)
Query: 173 KVKERFDEIFDADKYSDCLDRLKKIRK----DYAQNLKLLENYATTV-KAKQK------E 221
K+K+ DEI D ++ L + +K+ + D NL E A + K K K E
Sbjct: 864 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 923
Query: 222 LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFIL-LESQNQE---KIDKRNEQIVETAKI 277
LE KK +E EK+ + + ++++ I L++Q E ++ K+ E++ A +
Sbjct: 924 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL--QAAL 981
Query: 278 AEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
A +++ E+ A + + + L+ D +++ ++ EK+ + +E + T+
Sbjct: 982 ARLDD--EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1039
Query: 338 XXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN--IEE 395
H QA EL +E+
Sbjct: 1040 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1099
Query: 396 CQQEINEDEKAVEQYEQEMDELSQKITKL----QKQTAKLKEKEMIEENLKTK----EKQ 447
++ +K + E+E +L+ ++ L Q+ K K+ E + L++K E+
Sbjct: 1100 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1159
Query: 448 LIVLKNK-HK--TALMELLGNVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L +K HK + + G + E + A+ + K + +++ +
Sbjct: 1160 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1219
Query: 504 EAERKHIRE---SLNERRSELTKAEDKIYKACGTQPYDVTLSK-----YTTTVEKLQDEQ 555
+ + + E SL ++ E +A+ + + T ++ SK + +TVE L++ +
Sbjct: 1220 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1279
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
Q I Q ++ + ++ + + ++ +
Sbjct: 1280 KRFQKE---IENLTQQYEEKAAA------YDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1330
Query: 616 LQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVEEIT-- 669
L++ K D++L+ K+++ K +D E + E + + + ++ E EE+
Sbjct: 1331 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1390
Query: 670 --MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
M E E +++ + ++ L++ + ++T ++ + E+ D + + T D
Sbjct: 1391 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATEDAKLR 1449
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDIVNLEE 786
+V+ + ++ ++ ++LQ L+E +T+ ++E LE
Sbjct: 1450 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1509
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
K L+ + L+ +K+ + + E R +RD I A + K
Sbjct: 1510 DLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELEDARASRDEIFATAKENEK--- 1565
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKIDTLKDE 904
K KSL+A++ Q ++ E + Q +K L E+ ++ R L + L+
Sbjct: 1566 ---KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1622
Query: 905 IAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESLIIKQT 961
IA+ E +L++ +A +D + +Q ++L NE + + NE + +Q
Sbjct: 1623 IAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN 1679
Query: 962 KLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
K + K E GA+ S+ K ++ ++ + L + +E++ REK K DK ++E
Sbjct: 1680 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKDKKLKE 1738
Query: 1020 YAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
+ + ++ + E ++E+ E N +++L R++
Sbjct: 1739 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1771
Score = 50.0 bits (114), Expect = 5e-05
Identities = 137/822 (16%), Positives = 316/822 (38%), Gaps = 62/822 (7%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKA 151
+ L+ R+ + A +K+ + L++ + +++ T D ++ +L +E+ V K
Sbjct: 1010 EDLDSERAARNKAEKQKRDLGEELEALKTELED---TLDSTATQQELRAKREQEVTVLKK 1066
Query: 152 ILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC-LDR----LKKIRKDYAQNLK 206
L+ H+ + + E E + K + LD+ L+K D A L+
Sbjct: 1067 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1126
Query: 207 LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE------KSSNEIEYNKFILLESQN 260
+L V+ K+K+LE ++ S + E+ E K NE+E +L E++
Sbjct: 1127 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1186
Query: 261 QEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEE 320
+ I + ++++ + + + + +T ++ +TK + L+ + + Q DEE
Sbjct: 1187 KA-IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK-----LRQLEEERNSLQDQLDEE 1240
Query: 321 EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXX 380
+ Q + + Q +
Sbjct: 1241 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 1300
Query: 381 XXXHKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIE 438
K + +++ +++ + V E++ + Q + + + ++K E++ E
Sbjct: 1301 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1360
Query: 439 ENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXX 497
+ KE + + L AL E L E + + K E E + +
Sbjct: 1361 AEAREKETKALSLAR----ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1416
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAED-KIYKACGTQPYDVTLSK-YTTTVEKLQDEQ 555
LE + + ++ L E EL ED K+ Q + E+ ++++
Sbjct: 1417 KSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1476
Query: 556 NVLQSSMFIIN-KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX----XMNVPGKLE 610
LQ + + + + K + + E + + + KL+
Sbjct: 1477 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1536
Query: 611 KVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+D QR A A +DEI + NEK + ++ QL++ + + K + E
Sbjct: 1537 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1596
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVA 725
E+ L A + G + D + + + E ++E+ G++++ + A
Sbjct: 1597 ELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1647
Query: 726 TAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
T + +++T R+ + ++ +++L NK+L++ L+E + K + +T I
Sbjct: 1648 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST------I 1701
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGS 838
LE QL+ ++ + LKE ++E + ++ + ++ E G+
Sbjct: 1702 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1761
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 1762 ARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 1802
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 69.7 bits (163), Expect = 6e-11
Identities = 148/716 (20%), Positives = 293/716 (40%), Gaps = 58/716 (8%)
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
E+ + + DEL + + QK +LKE E L T+EK L+ + A EL
Sbjct: 864 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLL---QEQLQAETELYAEAE 919
Query: 468 EKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK 527
E + K E E + L+AERK + + + + +L + E
Sbjct: 920 EMRVRLAAKKQELE--EILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAA 977
Query: 528 IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFEN 587
K Q VT ++KL+DE V+ ++K + L++ N E
Sbjct: 978 RQK---LQLEKVTAE---AKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE 1031
Query: 588 ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQL 647
E M + ++ L++ + E+ +K E + +I L
Sbjct: 1032 EKAKNLTKLKNKHESM-----ISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1086
Query: 648 EKRIVDVDTQIKTLNETVEEITMSL-IEPEQKMTTAKQI---HGDMPMLDRYIQEIKTVT 703
+ +I ++ Q+ E ++ L E QK K+I G + L + +
Sbjct: 1087 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1146
Query: 704 KKFEAVKEQCGD------VDSEMTLD-VATAKQVDFK--QKISTLRNRVKTTQKKLNAHN 754
K E K G+ + E TLD AT +++ K Q+++ L+ K ++ +H
Sbjct: 1147 NKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK---KALDEETRSHE 1203
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAITPLE 813
++Q + +K +A EEL ++ + NL+++K+ L+ + A +E
Sbjct: 1204 AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVE 1263
Query: 814 VALKEKIEAKT-EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK------KKNV 866
K+K+EA+ E+ + D A + KV N+V+S+ + + + K+V
Sbjct: 1264 -HKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDV 1322
Query: 867 PREMEKIQEANDKLMEKQKQ---IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
++Q+ + L E+ +Q + T + L ++ ++L+D++ ++ K++L+ ++
Sbjct: 1323 ASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLN 1382
Query: 924 AQTDITNWQKQD-DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
Q + + QD E L K E E+L T+ +++KA L + K L+
Sbjct: 1383 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL----TQQYEEKAAAYDKLEKTKNRLQ 1438
Query: 983 GFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHREKMENI 1039
++L L + + +K + A +K+I +YA D+ E REK
Sbjct: 1439 QELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAE-AREKETKA 1497
Query: 1040 NMIIRELWRKIYRGNDID----YIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDM 1091
+ R L + +++ ++ + E ++ + + K + + +SK +E M
Sbjct: 1498 LSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQM 1553
Score = 60.1 bits (139), Expect = 5e-08
Identities = 149/738 (20%), Positives = 305/738 (41%), Gaps = 94/738 (12%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-KEKEM 436
K A+ L++EE ++ E+E A ++ + E KI KL+ Q KL KE+++
Sbjct: 959 KMAQQMLDLEE---QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 1015
Query: 437 IEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEV 486
+EE + + K K L LKNKH++ + EL + +++ K E+
Sbjct: 1016 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE------KSRQELEKLK 1069
Query: 487 XXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTT 546
L+A+ ++ L ++ EL A ++ + + L K
Sbjct: 1070 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRE 1127
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
+ D Q L S NK + Q +D G E E+ +
Sbjct: 1128 LEGHISDLQEDLDSERAARNKAEKQKRD--------LGEELEA-----------LKTELE 1168
Query: 607 GKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L+ + + ++ E+ +K ++ T + ++ ++ ++ ++ L E +E
Sbjct: 1169 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA---VEELTEQLE 1225
Query: 667 EITMSLIE-PEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
+ + + K T K+ + G++ +L + QE++ KK EA Q ++ S+ +
Sbjct: 1226 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA---QVQELQSKCS- 1281
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
D A+ + K+ L+N V++ LN K L + +L +TQ+ +Q
Sbjct: 1282 DGERAR-AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ--- 1337
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE++++L L+ L E++EAK + R L S
Sbjct: 1338 --EETRQKLN-----VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 1390
Query: 843 KVEVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
K++ + V++L+ ++ +K +N+ ++ E+ A DKL + + ++ + L +D
Sbjct: 1391 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1450
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+ ++ E +R D L K +I++ K DE + + E EKE+ +
Sbjct: 1451 QRQLVSNLEKKQRKFDQLLAEEK---NISS--KYADERDRA-----EAEAREKETKALSL 1500
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIRE 1019
+ ++ E L K LK +L S D+ K ++EL +K A++ + E
Sbjct: 1501 ARALEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGK----NVHELEKSKRALETQMEE 1555
Query: 1020 YAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYR 1079
L++ +E + E+ + + E+ + +G ++ + E N E +RR+ +
Sbjct: 1556 MKTQLEE--LEDELQATEDAKLRL-EVNMQALKGQFERDLQARDEQN---EEKRRQLQRQ 1609
Query: 1080 VVQSKNGVEIDMRGRCSA 1097
+ + + +E + + R A
Sbjct: 1610 LHEYETELEDERKQRALA 1627
Score = 60.1 bits (139), Expect = 5e-08
Identities = 171/933 (18%), Positives = 378/933 (40%), Gaps = 80/933 (8%)
Query: 173 KVKERFDEIFDADKYSDCLDRLKKIRK----DYAQNLKLLENYATTV-KAKQK------E 221
K+K+ DEI D ++ L + +K+ + D NL E A + K K K E
Sbjct: 991 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 1050
Query: 222 LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFIL-LESQNQE---KIDKRNEQIVETAKI 277
LE KK +E EK+ + + ++++ I L++Q E ++ K+ E++ A +
Sbjct: 1051 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL--QAAL 1108
Query: 278 AEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
A +++ E+ A + + + L+ D +++ ++ EK+ + +E + T+
Sbjct: 1109 ARLDD--EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 1166
Query: 338 XXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN--IEE 395
H QA EL +E+
Sbjct: 1167 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 1226
Query: 396 CQQEINEDEKAVEQYEQEMDELSQKITKL----QKQTAKLKEKEMIEENLKTK----EKQ 447
++ +K + E+E +L+ ++ L Q+ K K+ E + L++K E+
Sbjct: 1227 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 1286
Query: 448 LIVLKNK-HK--TALMELLGNVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L +K HK + + G + E + A+ + K + +++ +
Sbjct: 1287 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 1346
Query: 504 EAERKHIRE---SLNERRSELTKAEDKIYKACGTQPYDVTLSK-----YTTTVEKLQDEQ 555
+ + + E SL ++ E +A+ + + T ++ SK + +TVE L++ +
Sbjct: 1347 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 1406
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
Q I Q ++ + ++ + + ++ +
Sbjct: 1407 KRFQKE---IENLTQQYEEKAAA------YDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 1457
Query: 616 LQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVEEIT-- 669
L++ K D++L+ K+++ K +D E + E + + + ++ E EE+
Sbjct: 1458 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 1517
Query: 670 --MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
M E E +++ + ++ L++ + ++T ++ + E+ D + + T D
Sbjct: 1518 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATEDAKLR 1576
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDIVNLEE 786
+V+ + ++ ++ ++LQ L+E +T+ ++E LE
Sbjct: 1577 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1636
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
K L+ + L+ +K+ + + E R +RD I A + K
Sbjct: 1637 DLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELEDARASRDEIFATAKENEK--- 1692
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKIDTLKDE 904
K KSL+A++ Q ++ E + Q +K L E+ ++ R L + L+
Sbjct: 1693 ---KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 1749
Query: 905 IAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESLIIKQT 961
IA+ E +L++ +A +D + +Q ++L NE + + NE + +Q
Sbjct: 1750 IAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN 1806
Query: 962 KLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
K + K E GA+ S+ K ++ ++ + L + +E++ REK K DK ++E
Sbjct: 1807 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKDKKLKE 1865
Query: 1020 YAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
+ + ++ + E ++E+ E N +++L R++
Sbjct: 1866 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1898
Score = 50.0 bits (114), Expect = 5e-05
Identities = 137/822 (16%), Positives = 316/822 (38%), Gaps = 62/822 (7%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKA 151
+ L+ R+ + A +K+ + L++ + +++ T D ++ +L +E+ V K
Sbjct: 1137 EDLDSERAARNKAEKQKRDLGEELEALKTELED---TLDSTATQQELRAKREQEVTVLKK 1193
Query: 152 ILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC-LDR----LKKIRKDYAQNLK 206
L+ H+ + + E E + K + LD+ L+K D A L+
Sbjct: 1194 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 1253
Query: 207 LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE------KSSNEIEYNKFILLESQN 260
+L V+ K+K+LE ++ S + E+ E K NE+E +L E++
Sbjct: 1254 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 1313
Query: 261 QEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEE 320
+ I + ++++ + + + + +T ++ +TK + L+ + + Q DEE
Sbjct: 1314 KA-IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK-----LRQLEEERNSLQDQLDEE 1367
Query: 321 EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXX 380
+ Q + + Q +
Sbjct: 1368 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 1427
Query: 381 XXXHKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIE 438
K + +++ +++ + V E++ + Q + + + ++K E++ E
Sbjct: 1428 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 1487
Query: 439 ENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXX 497
+ KE + + L AL E L E + + K E E + +
Sbjct: 1488 AEAREKETKALSLAR----ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 1543
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAED-KIYKACGTQPYDVTLSK-YTTTVEKLQDEQ 555
LE + + ++ L E EL ED K+ Q + E+ ++++
Sbjct: 1544 KSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 1603
Query: 556 NVLQSSMFIIN-KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX----XMNVPGKLE 610
LQ + + + + K + + E + + + KL+
Sbjct: 1604 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 1663
Query: 611 KVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+D QR A A +DEI + NEK + ++ QL++ + + K + E
Sbjct: 1664 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 1723
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVA 725
E+ L A + G + D + + + E ++E+ G++++ + A
Sbjct: 1724 ELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1774
Query: 726 TAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
T + +++T R+ + ++ +++L NK+L++ L+E + K + +T I
Sbjct: 1775 TQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST------I 1828
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGS 838
LE QL+ ++ + LKE ++E + ++ + ++ E G+
Sbjct: 1829 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 1888
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 1889 ARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 1929
>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
Length = 1635
Score = 69.7 bits (163), Expect = 6e-11
Identities = 129/626 (20%), Positives = 264/626 (42%), Gaps = 58/626 (9%)
Query: 402 EDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKE-----KQLIVLKN--- 453
E++ + Q E+ S+ +K+ +KE E ++ L+ KE +LI+LK+
Sbjct: 825 ENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELILLKDSLA 884
Query: 454 KHKTALMELLGNVPEKDFAVTINKFECEVRNE-VXXXXXXXXXXXXXXXXLEAERKHIRE 512
K + + L +V E + + + EC+ + E + E + ++E
Sbjct: 885 KSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKE 944
Query: 513 SLNERRSELTKAEDKIYKAC-GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQ 571
L RSE + + G + Y L +Y E+L E+ + I Q
Sbjct: 945 ELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQ 1004
Query: 572 LKDNSC-CPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMK 630
L++++ C N +NE + LE ++QRA A D+ L +
Sbjct: 1005 LRNSTLQCETINS--DNEDLLARIETLQSNAKL-----LEVQILEVQRAKAMVDKELEAE 1057
Query: 631 SLNEKITTLKD--TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGD 688
L +K +K+ T + +LE+ V + + K L +T++E+ L++ + + TT +
Sbjct: 1058 KL-QKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQEL--ELVKKDAQQTTLM----N 1110
Query: 689 MPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQK 748
M + D Y + +K + +K + D++ E+ + KQK TL+ + + Q
Sbjct: 1111 MEIAD-YERLMKELNQKLTNKNNKIEDLEQEIKIQ---------KQKQETLQEEITSLQS 1160
Query: 749 KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXA 808
+ + +K + + K K+EL ++++ D + L+ S K
Sbjct: 1161 SVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAE 1220
Query: 809 ITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPR 868
IT + + E + KT + R L SAY +V + ++ AE + V
Sbjct: 1221 ITSEKHKIHEHL--KTSAEQHQRTL----SAYQQRVTALQEECRAAKAE-----QATVTS 1269
Query: 869 EME--KIQEANDKLMEKQKQI-MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQ 925
E E K++ N +K K + + + ++ + L+ I + ++ +D +NL +
Sbjct: 1270 EFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQIN--V 1327
Query: 926 TDITNWQKQDDELNEKLNGINKEELNE----KESLIIKQTKLFQQKAECTGALSELKKSL 981
+++ Q + D L E+ N + +E +++ +E L Q++ K+E T +S+L
Sbjct: 1328 SELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQN 1387
Query: 982 KGFRNELEKSLSKDIEKKFREKMYEL 1007
+ RN + + ++++ R+ + L
Sbjct: 1388 EVLRNSFRDQV-RHLQEEHRKTVETL 1412
Score = 60.9 bits (141), Expect = 3e-08
Identities = 135/703 (19%), Positives = 291/703 (41%), Gaps = 74/703 (10%)
Query: 386 QAENELNIEECQQEINEDEKAVEQY----EQEMDELS--QKITKLQKQTAKLKEKEMIEE 439
Q +E N+++ Q+EI + E+ ++++D + +K T Q Q + ++
Sbjct: 124 QNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQK 183
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVPE--KDFAVTINKFECEVRNEVXXXXXXXXXXX 497
N+ + +++L+ LK H+ + EL+ + K+ INK E++ +
Sbjct: 184 NINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLN-ELKENLVKQCEASEKNI 242
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGT-QPYDVTLSKYTTTVEKLQDEQN 556
E E +++R++ + + + + Q + + T+++L+ + +
Sbjct: 243 QKKY--ECELENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHS 300
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPG-KLEKVTED 615
+L+ + +N K +L+ ++ F +E E G +EK+ +
Sbjct: 301 ILKDEVTYMNNLKLKLEMDA--QHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSE 358
Query: 616 LQRASAK--------KDEILSMKSLNEK-ITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L + + E+ S+K ++K I+ L +T + EK + + +I+ L E E
Sbjct: 359 LAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCE 418
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIK-TVTKKFEAVKEQCGDVDSEMTLDVA 725
+ E ++ + + + M +L + E ++++FE++K+Q E+ +
Sbjct: 419 NLQQ---EKQEAILNYESLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLR 475
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD-IVNL 784
TA F +K + L T +L N+KL + E + + + N Q+K +++L
Sbjct: 476 TA----FTEKDALLE-----TVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSL 526
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
+ L+ I L+ + +E + R R ++E G KV
Sbjct: 527 SQRDTMLKELEGKINSLTEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGK----KV 582
Query: 845 EVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLK 902
E L+ ++ + + +E ++ + +KLM + K + D++VL+ ++ +L
Sbjct: 583 EQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLY 642
Query: 903 DEIAKQEVYKRDLDDNLCLRKAQTD-------ITNWQKQDDELNEKLNGINKEELNEKES 955
+E K K+ L +L + +Q + IT +K+ + E+ + +NK NE+
Sbjct: 643 EENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQ 702
Query: 956 LIIKQTKLF-----------------------QQKAECTGALSELKKSLKGFRNELEKSL 992
+ +T+L+ Q E ++E K +L R+E L
Sbjct: 703 KLFVKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLEL 762
Query: 993 SKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
K+I+ E + + K++ +D + V L K L E EK
Sbjct: 763 EKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEK 805
Score = 54.0 bits (124), Expect = 3e-06
Identities = 124/624 (19%), Positives = 263/624 (42%), Gaps = 45/624 (7%)
Query: 384 HKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENL 441
H++ +N E ++ I E K VEQ Q EL QK+ +L + LKEK+ ++ L
Sbjct: 558 HEEMDNFHKKCEREERLILELGKKVEQTIQYNSELEQKVNELTGGLEETLKEKDQNDQKL 617
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
+ Q+ VL ++ K L + ++ E++ ++ K + EV
Sbjct: 618 EKLMVQMKVL-SEDKEVLSAEVKSLYEENNKLSSEKKQLSRDLEVFLSQKEDVILKEHIT 676
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSS 561
LE + + + E + ++L + E TQ Y L + + V + +E++V+ +
Sbjct: 677 QLEKKLQLMVEE-QDNLNKLLENEQVQKLFVKTQLYGF-LKEMGSEVSEDSEEKDVV-NV 733
Query: 562 MFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASA 621
+ + + ++ + CN F+ + + + E++ L+
Sbjct: 734 LQAVGESLAKINEEK----CNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLR--DY 787
Query: 622 KKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN--ETVEEITM----SLIEP 675
+++++L K L E + + + LE + + T+++ N VEE++ S I
Sbjct: 788 EQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTCSKSEIHN 847
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFK-- 733
E++ K+ P+L++ +E++ + +K+ S +++ K+++ K
Sbjct: 848 EKEKCFIKEHENLKPLLEQ--KELRDRRAELILLKDSLAKSPSVKNDPLSSVKELEEKIE 905
Query: 734 ----------QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
+KI+ ++ +K+L++ K+ QT+ E+ + E ++D++
Sbjct: 906 NLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQ 965
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
ES K L + E +++ + + +A+
Sbjct: 966 GAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLTRQLRNSTLQCETINSDNEDLLAR 1025
Query: 844 VEVAFNKVKSLDAEI--QQHKKKNVPREM--EKIQEANDKLMEKQKQI--MTDRQV-LTK 896
+E + K L+ +I Q K V +E+ EK+Q+ K+ E + + + QV L K
Sbjct: 1026 IETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQK-EQKIKEHATTVNELEELQVQLQK 1084
Query: 897 KIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL-NGINKEELNEKES 955
+ L+ + + E+ K+D + +I ++++ ELN+KL N NK E E+E
Sbjct: 1085 EKKQLQKTMQELELVKKDAQQTTLM---NMEIADYERLMKELNQKLTNKNNKIEDLEQEI 1141
Query: 956 LIIKQTKLFQQKAECTGALSELKK 979
I KQ + Q+ E T S +++
Sbjct: 1142 KIQKQKQETLQE-EITSLQSSVQQ 1164
Score = 42.3 bits (95), Expect = 0.010
Identities = 65/296 (21%), Positives = 121/296 (40%), Gaps = 26/296 (8%)
Query: 179 DEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEK 238
D + + + ++ L+K K+ + + ++ A VKAK KEL+ S K+ + +E E
Sbjct: 892 DPLSSVKELEEKIENLEKECKEKEEKINKIKLVA--VKAK-KELDSSRKETQTVKEELES 948
Query: 239 IANEK-----SSNEI----EYNKFILLESQNQ-EKIDKRNEQIVETAKIAEIENITEVQT 288
+ +EK S ++ E K +LLE + Q E++D E+ IE++T
Sbjct: 949 LRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEH--RIEDLTRQLR 1006
Query: 289 N-----EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHT----QXX 339
N E + + +L ++E+L+S+ K+ + Q E ++ A+ VD+ Q
Sbjct: 1007 NSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQR-AKAMVDKELEAEKLQKEQKI 1065
Query: 340 XXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQ-AENELNIEECQQ 398
+ ++ + + A+ E ++E Q
Sbjct: 1066 KEHATTVNELEELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQ 1125
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNK 454
++ +E EQE+ QK LQ++ L+ E TK KQL+V K
Sbjct: 1126 KLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKK 1181
Score = 38.7 bits (86), Expect = 0.12
Identities = 101/478 (21%), Positives = 201/478 (42%), Gaps = 50/478 (10%)
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
LEK + Q S KK+ I + + + +T + D +LE+ ++ +I+ L + +
Sbjct: 34 LEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAH-KELEQSHINYVKEIENLKNELMAV 92
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK 728
E K KQ+ M +++K + VK+ +++ + +
Sbjct: 93 RSKY--SEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEK---IRPGFEE 147
Query: 729 QVDFKQK-ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKA-KEELLNT----QKKVQDIV 782
Q+ + QK + + K T +L + Y+K + +EELL Q++V++++
Sbjct: 148 QILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVKELM 207
Query: 783 -NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR-----NRD---- 832
+E S K+ +++ E +++K E + E +R+ N+D
Sbjct: 208 CQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQIC 267
Query: 833 -LIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL-MEKQKQIMTD 890
++ + ++ +V KVK L+ +++ + ++ + E N KL +E Q + D
Sbjct: 268 SILLQENTFVE--QVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKD 325
Query: 891 -----RQVLTKKIDTL---KDE----IAKQEVYKRDLDDNLCL------RKAQTDITNWQ 932
R+ L KI+ L K+E I K + L+ C R+ Q+ Q
Sbjct: 326 EFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQ 385
Query: 933 KQDDELNEK-LNGINKEELN---EKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNEL 988
K+ ELNE L+ KE+L E + L + L Q+K E L++ ++ + EL
Sbjct: 386 KEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTEL 445
Query: 989 EKSLSKDIEKKFRE-KMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
+S K I ++F K + + + +R D L +R + EN ++ ++
Sbjct: 446 GESAGK-ISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLSQQ 502
Score = 33.5 bits (73), Expect = 4.7
Identities = 34/138 (24%), Positives = 61/138 (44%), Gaps = 8/138 (5%)
Query: 191 LDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSY-KKNTSFNKEEEKIANEKSSNEIE 249
+ L+ ++KD AQ L+ + KEL KN E++I +K E
Sbjct: 1093 MQELELVKKD-AQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETL 1151
Query: 250 YNKFILLES---QNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENAT-KTILEKVES 305
+ L+S Q +EK K + +V+T K E+ + + +T+ A+ K LE +
Sbjct: 1152 QEEITSLQSSVQQYEEKNTKIKQLLVKTKK--ELADSKQAETDHLILQASLKGELEASQQ 1209
Query: 306 LKSDHKVQKSQADEEEKK 323
+K+Q ++ E+ K
Sbjct: 1210 QVEVYKIQLAEITSEKHK 1227
Score = 33.1 bits (72), Expect = 6.2
Identities = 85/438 (19%), Positives = 178/438 (40%), Gaps = 46/438 (10%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDEL---SQKITKLQKQTAK----LKE--K 434
H NEL EE Q ++ +++K +++ QE++ + +Q+ T + + A +KE +
Sbjct: 1068 HATTVNEL--EELQVQLQKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQ 1125
Query: 435 EMIEENLKTK--EKQLIVLKNKHK------TALMELLGNVPEKDFAV--TINKFECEVRN 484
++ +N K + E+++ + K K + T+L + EK+ + + K + E+ +
Sbjct: 1126 KLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELAD 1185
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGT--QPYDVTLS 542
LEA ++ + E + +E+T + KI++ T + + TLS
Sbjct: 1186 SKQAETDHLILQASLKGELEASQQQV-EVYKIQLAEITSEKHKIHEHLKTSAEQHQRTLS 1244
Query: 543 KYTTTVEKLQDEQNVLQSSMFII----NKYK-------GQLKDNSCCPLCNRGFENESEX 591
Y V LQ+E ++ + YK Q K+ S G + E E
Sbjct: 1245 AYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREH 1304
Query: 592 XXXXXXXXXXXM-NVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKR 650
+ + L+ +LQ ++ D +L + + T K+ E+ +
Sbjct: 1305 LEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREKLCS 1364
Query: 651 IVDVDTQIKTLN-ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAV 709
I + +K+ + +TV ++T S E + + H + + + + ++T+ ++ +
Sbjct: 1365 IQSENMMMKSEHTQTVSQLT-SQNEVLRNSFRDQVRH----LQEEHRKTVETLQQQLSKM 1419
Query: 710 KEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE 769
+ Q + +E T T V +Q + LR R T L+ H + +T E
Sbjct: 1420 EAQLFQLKNEPT----TRSPVSSQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTE 1475
Query: 770 ELLNTQKKVQDIVNLEES 787
+ + Q + L S
Sbjct: 1476 SVSSASTYTQSLEQLLNS 1493
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 68.9 bits (161), Expect = 1e-10
Identities = 101/441 (22%), Positives = 200/441 (45%), Gaps = 35/441 (7%)
Query: 629 MKSLNEKITTLKDTE--IPQLE--KRIVDVDTQIK---TLNETVEEITMSLIEPEQKMTT 681
M + IT L+D + I QLE K +V +T+ + TL EEI +Q T
Sbjct: 1 MAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQ 60
Query: 682 AKQIHGDMPMLDRYIQE-----IKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ--VDFKQ 734
+++ +R E + T K EA ++ ++D ++ T+++ + +Q
Sbjct: 61 GEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 120
Query: 735 KISTLRNRVKTTQKKLNAHN-KKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQ- 792
++S ++ V KK + KLQ L+EK+ KE+ L + + ++ E+ K L+
Sbjct: 121 ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEK 180
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV-EVAFNKV 851
S LE +K TE + RDL + Y ++ E+ +
Sbjct: 181 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLE 240
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVY 911
KSL Q K V E EK + N ++ ++ T+ + L + D L E K +V
Sbjct: 241 KSLQENKNQSKDLAVHLEAEK-NKHNMEITVMVEKHKTELESLKHQQDALWTE--KLQVL 297
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEK--LNGINKEELNEK--ESLIIKQTKLFQQK 967
K+ + + + + Q+++ L +K + + EE+NEK E L +KQT+L
Sbjct: 298 KQQYQTEMEKLREKCE----QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLS 353
Query: 968 AECTGALS---ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVAL 1024
+E + L +L++ L +++ +K + +++E K E+ + H + +D I+E+ V++
Sbjct: 354 SELSEVLKARHKLEEELSVLKDQTDK-MKQELEAKMDEQ--KNHHQQQVDSIIKEHEVSI 410
Query: 1025 DKCLMEFHREKMENINMIIRE 1045
+ ++++ + ++++E
Sbjct: 411 QRTEKAL-KDQINQLELLLKE 430
Score = 60.5 bits (140), Expect = 4e-08
Identities = 82/401 (20%), Positives = 181/401 (45%), Gaps = 23/401 (5%)
Query: 388 ENELNIEECQQEI-NEDEKAVEQYEQEMDELSQKITKL-QKQTAKLKEKEMIEENLKTKE 445
E E ++E+ QE N+ + E E ++ + +IT + +K +L+ + ++ L T++
Sbjct: 234 ELESSLEKSLQENKNQSKDLAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDALWTEK 293
Query: 446 KQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEA 505
Q VLK +++T + +L ++ + +K E+ L+
Sbjct: 294 LQ--VLKQQYQTEMEKLREKCEQEKETLLKDK-------EIIFQAHIEEMNEKTLEKLDV 344
Query: 506 ERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM-FI 564
++ + ESL+ SE+ KA K+ + D T K+ +++N Q + I
Sbjct: 345 KQTEL-ESLSSELSEVLKARHKLEEELSVLK-DQTDKMKQELEAKMDEQKNHHQQQVDSI 402
Query: 565 INKYKGQLK--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
I +++ ++ + + N+ E N+ +++ +LQ+ASAK
Sbjct: 403 IKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAK 462
Query: 623 KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTA 682
D S +S + T + ++ QL+++++D++T+ L + V E+ + ++
Sbjct: 463 LDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAH 522
Query: 683 K-QIHGDMPMLDR----YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIS 737
K Q+ M L++ Q++K++T+ +E+ K + G+ + E T + K+ Q
Sbjct: 523 KIQVQDLMQQLEKQNSEMEQKVKSLTQVYES-KLEDGNKEQEQTKQILVEKENMILQMRE 581
Query: 738 TLRNRVKTTQKKLNAHNKKLQTLYEK-KTKAKEELLNTQKK 777
+ ++ +KL+A + L E+ +TK K++ +KK
Sbjct: 582 GQKKEIEILTQKLSAKEDSIHILNEEYETKFKKKKKKKKKK 622
Score = 44.8 bits (101), Expect = 0.002
Identities = 75/395 (18%), Positives = 167/395 (42%), Gaps = 23/395 (5%)
Query: 189 DCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEI 248
+ +D +KK ++ Q KL + + + K++EL + +E+ K+A EKS +
Sbjct: 128 EVVDVMKKSSEE--QIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQS-- 183
Query: 249 EYNKFILLESQNQEKIDKRNEQIVETAKIAEIEN-ITEVQTNEEAENATKTILEKVESLK 307
EY K I E + QE + ++ + A + E EN + ++Q +EAE ILE SL+
Sbjct: 184 EYLK-ISQEKEQQESLALEELELQKKAILTESENKLRDLQ--QEAETYRTRILELESSLE 240
Query: 308 SDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSX 367
+ K+Q+ K ++ ++ H + +
Sbjct: 241 KSLQENKNQS----KDLAVHLEAEKNKHNMEITVMVEKHKTELESLKHQQDALWTEKLQV 296
Query: 368 XXXXXXXXXXXXXXXXHKQAENELNIEEC--QQEINE-DEKAVEQY---EQEMDELSQKI 421
++ E L +E Q I E +EK +E+ + E++ LS ++
Sbjct: 297 LKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSEL 356
Query: 422 TKLQKQTAKLKEKEMIEENLKTKEKQLIVLK-NKHKTALMELLGNVPEKDFAVTINKFEC 480
+++ K KL+E+ + ++ K KQ + K ++ K + + ++ K+ V+I + E
Sbjct: 357 SEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSI-IKEHEVSIQRTEK 415
Query: 481 EVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK--IYKACGTQPYD 538
+++++ +A +++ + EL +A K ++++ + ++
Sbjct: 416 ALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHE 475
Query: 539 VTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLK 573
T Y + +LQ + L++ ++ K +++
Sbjct: 476 QT-KAYEEQLAQLQQKLLDLETERILLTKQVAEVE 509
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 68.5 bits (160), Expect = 1e-10
Identities = 167/901 (18%), Positives = 364/901 (40%), Gaps = 84/901 (9%)
Query: 101 KVTALAKKKTKF-QTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFC 159
KV +L K K+K Q ++ S++++ K + DL+ + G K S++
Sbjct: 244 KVNSLNKTKSKLEQQVEDLESSLEQEKKLR------VDLERNKRKLEGDLKLAQESIL-- 295
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSD----CLDRLKKIRKDYAQNLKLLENYAT-- 213
E+ LDE K K+ F+ K D L KKI++ A+ +L E
Sbjct: 296 DLENDKQQLDERLKKKD-FEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 354
Query: 214 TVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK-----FILLESQNQEKIDKRN 268
+AK ++ Y + E + A +S +IE NK F+ L ++ E+ ++
Sbjct: 355 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLR-RDLEEATLQH 413
Query: 269 EQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ---KSQADEEEKKAQ 325
E +V T + +++ E+ E+ +N + + +K+E KS+ K++ S + E K++
Sbjct: 414 EAMVATLRKKHADSVAEL--GEQIDNLQR-VKQKLEKEKSEFKLEIDDLSSSMESVSKSK 470
Query: 326 GFVDE-CRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXX--X 382
+++ CR+ Q ++
Sbjct: 471 ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLS 530
Query: 383 XHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE-KEMIEENL 441
KQA + EE ++++ E+ KA + L++Q + +E K ++ L
Sbjct: 531 RSKQAFTQ-QTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 589
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
++ + K++T ++ + E + + E +V
Sbjct: 590 SKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSE--EQVEAVNAKCASLEKTKQ 647
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQ-------DE 554
L+ E + + + ER + L A DK + +D L+++ T E+ Q E
Sbjct: 648 RLQGEVEDLMVDV-ERANSLAAALDKKQRN-----FDKVLAEWKTKCEESQAELEASLKE 701
Query: 555 QNVLQSSMFII-NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
L + +F + N Y+ L N+ E E ++ K K
Sbjct: 702 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 761
Query: 614 E----DLQRASAKKDEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNETVE-- 666
E D+Q A + + L + L+ T++ +++++I + D +I+ L +
Sbjct: 762 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRT 821
Query: 667 -EITMSLIEPE-----QKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDV-DS 718
E S ++ E + + K++ GD+ ++ + + + + ++ G + D+
Sbjct: 822 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 881
Query: 719 EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
++ LD A Q D K++++ + R Q ++ L+ + A++ELL++ ++V
Sbjct: 882 QLHLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 941
Query: 779 QDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI---EAKTEVVRRNR 831
Q + +L +KK+L++D E K+ I E +++ +
Sbjct: 942 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 1001
Query: 832 DLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
D SA++ +++ + VK L + + ++ + ++IQ+ ++ E + ++ +
Sbjct: 1002 DT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 1057
Query: 891 RQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCLR------KAQTDITNWQKQDDELNEKL 942
++ T+ + L+ + K+ Y+ + D LR K Q + ++++Q +E +E+
Sbjct: 1058 QKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQA 1117
Query: 943 N 943
N
Sbjct: 1118 N 1118
Score = 57.2 bits (132), Expect = 3e-07
Identities = 126/671 (18%), Positives = 269/671 (40%), Gaps = 77/671 (11%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQK------ITKLQKQTAKL 431
K E + IEE ++EI + EK Y +E++ELS++ +T Q + K
Sbjct: 335 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 394
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E + L+ KH ++ EL + + + K + E +
Sbjct: 395 REAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 454
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + L+E R + ++I + +LS+
Sbjct: 455 EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK----NEEIQR---------SLSEL 501
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
TT +LQ E L + QL + + F ++E N
Sbjct: 502 TTQKSRLQTEAGELSRQLEEKESIVSQLSRS------KQAFTQQTEELKRQLEEENKAKN 555
Query: 605 -VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE-KRIVDVDTQIKTLN 662
+ L+ D + +E K+ ++ + ++E+ Q K D + + L
Sbjct: 556 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 615
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E E++ L + E+++ + ++ L++ Q ++ V++ DV+ +L
Sbjct: 616 EAQEKLAQRLQDSEEQV---EAVNAKCASLEKTKQRLQ------GEVEDLMVDVERANSL 666
Query: 723 DVA-TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
A KQ +F + ++ + + + +Q +L A K+ ++L + K K ++ + +
Sbjct: 667 AAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAY---EEALDQL 723
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGS 838
++ K L+ + I LE + K+ K ++ + +E
Sbjct: 724 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEE 783
Query: 839 AYIAKVEVAFNKVKS--------LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
A I ++++ +VKS D EI+Q K+N R +E +Q A D + + + +
Sbjct: 784 AKILRIQLELTQVKSEIDRKIAEKDEEIEQ-LKRNYQRTVETMQSALDAEVRSRNEAIRL 842
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQ-DDELNEKLNGINKEE 949
++ + ++ + EI ++ + LR Q + + Q DD L +E+
Sbjct: 843 KKKMEGDLNEI--EIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQ------TQED 894
Query: 950 LNEKESLIIKQTKLFQQKA-ECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
L E+ +++ ++ L Q + E L + +++ K EL S ++ ++ + +H
Sbjct: 895 LKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NERVQLLHTQNTSLIH 953
Query: 1009 VTKAIDKDIRE 1019
K ++ D+ +
Sbjct: 954 TKKKLETDLMQ 964
Score = 54.0 bits (124), Expect = 3e-06
Identities = 130/686 (18%), Positives = 271/686 (39%), Gaps = 50/686 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIE-ENLKT 443
K AE E + ++E + + + + E + EL +K+ L ++ L+ + E ENL
Sbjct: 69 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 128
Query: 444 KEK---QLIVLKNKHKTALMELLGNVP-EKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
E+ QLI K + + + E+ E++ + + ++ +E
Sbjct: 129 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 188
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E+ + EL+ ++ I K T+ + ++ LQ E++ +
Sbjct: 189 LAKVEKEKHATENKVKNLTEELSGLDETIAKL--TREKKALQEAHQQALDDLQAEEDKVN 246
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
S +NK K +L+ E E + +++ K+ DL+ A
Sbjct: 247 S----LNKTKSKLEQQ--VEDLESSLEQEKKLR----------VDLERNKRKLEGDLKLA 290
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDT-------QIKTLNETVEEITMSL 672
++ + K ++ KD E QL+ ++ D T +IK L +EE+ +
Sbjct: 291 QESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI 350
Query: 673 -IEPEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDVDSEMTLDVATA 727
E + T KQ ++ L ++E VT + E K++ + ++ D+ A
Sbjct: 351 EAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEF-LKLRRDLEEA 409
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEE 786
+ + ++TLR + + +L LQ + +K K K E L + ++ +
Sbjct: 410 -TLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSK 468
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKE----KIEAKTEVVRRNRDLIEAGS--AY 840
SK L+ C ++ +L E K +TE +R L E S +
Sbjct: 469 SKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQ 528
Query: 841 IAKVEVAF-NKVKSLDAEI-QQHKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
+++ + AF + + L ++ +++K KN + ++ + D L E+ ++ + L +
Sbjct: 529 LSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRA 588
Query: 898 IDTLKDEIAK-QEVYKRD-LDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
+ E+A+ + Y+ D + L +AQ + + +E E +N K+
Sbjct: 589 LSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQR 648
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L + L + L K + F L + +K E+ E L ++++
Sbjct: 649 LQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTK-CEESQAELEASLKESRSLST 707
Query: 1016 DIREYAVALDKCLMEFHREKMENINM 1041
++ + A ++ L + K EN N+
Sbjct: 708 ELFKLKNAYEEALDQLETVKRENKNL 733
Score = 46.4 bits (105), Expect = 6e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD 936
K+ K T++++ T K KDE+AK E +++L++ L + + Q Q +
Sbjct: 63 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 122
Query: 937 ELN-----EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
N E+ + + K + + E+ I + T+ + + E L+ K+ L+ +EL+K
Sbjct: 123 SENLLDAEERCDQLIKAKF-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 181
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + E H T+ K++ E LD+ + + REK
Sbjct: 182 ID-DLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREK 224
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 68.1 bits (159), Expect = 2e-10
Identities = 167/901 (18%), Positives = 364/901 (40%), Gaps = 84/901 (9%)
Query: 101 KVTALAKKKTKF-QTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFC 159
KV +L K K+K Q ++ S++++ K + DL+ + G K S++
Sbjct: 1017 KVNSLNKTKSKLEQQVEDLESSLEQEKKLR------VDLERNKRKLEGDLKLAQESIL-- 1068
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSD----CLDRLKKIRKDYAQNLKLLENYAT-- 213
E+ LDE K K+ F+ K D L KKI++ A+ +L E
Sbjct: 1069 DLENDKQQLDERLKKKD-FEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127
Query: 214 TVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK-----FILLESQNQEKIDKRN 268
+AK ++ Y + E + A +S +IE NK F+ L ++ E+ ++
Sbjct: 1128 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLR-RDLEEATLQH 1186
Query: 269 EQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ---KSQADEEEKKAQ 325
E +V T + +++ E+ E+ +N + + +K+E KS+ K++ S + E K++
Sbjct: 1187 EAMVATLRKKHADSVAEL--GEQIDNLQR-VKQKLEKEKSEFKLEIDDLSSSMESVSKSK 1243
Query: 326 GFVDE-CRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXX--X 382
+++ CR+ Q ++
Sbjct: 1244 ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLS 1303
Query: 383 XHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE-KEMIEENL 441
KQA + EE ++++ E+ KA + L++Q + +E K ++ L
Sbjct: 1304 RSKQAFTQ-QTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 1362
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
++ + K++T ++ + E + + E +V
Sbjct: 1363 SKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSE--EQVEAVNAKCASLEKTKQ 1420
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQ-------DE 554
L+ E + + + ER + L A DK + +D L+++ T E+ Q E
Sbjct: 1421 RLQGEVEDLMVDV-ERANSLAAALDKKQRN-----FDKVLAEWKTKCEESQAELEASLKE 1474
Query: 555 QNVLQSSMFII-NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
L + +F + N Y+ L N+ E E ++ K K
Sbjct: 1475 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 1534
Query: 614 E----DLQRASAKKDEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNETVE-- 666
E D+Q A + + L + L+ T++ +++++I + D +I+ L +
Sbjct: 1535 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRT 1594
Query: 667 -EITMSLIEPE-----QKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDV-DS 718
E S ++ E + + K++ GD+ ++ + + + + ++ G + D+
Sbjct: 1595 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 1654
Query: 719 EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
++ LD A Q D K++++ + R Q ++ L+ + A++ELL++ ++V
Sbjct: 1655 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 1714
Query: 779 QDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI---EAKTEVVRRNR 831
Q + +L +KK+L++D E K+ I E +++ +
Sbjct: 1715 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 1774
Query: 832 DLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
D SA++ +++ + VK L + + ++ + ++IQ+ ++ E + ++ +
Sbjct: 1775 DT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 1830
Query: 891 RQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCLR------KAQTDITNWQKQDDELNEKL 942
++ T+ + L+ + K+ Y+ + D LR K Q + ++++Q +E +E+
Sbjct: 1831 QKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQA 1890
Query: 943 N 943
N
Sbjct: 1891 N 1891
Score = 59.3 bits (137), Expect = 8e-08
Identities = 126/670 (18%), Positives = 271/670 (40%), Gaps = 75/670 (11%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQK------ITKLQKQTAKL 431
K E + IEE ++EI + EK Y +E++ELS++ +T Q + K
Sbjct: 1108 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 1167
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E + L+ KH ++ EL + + + K + E +
Sbjct: 1168 REAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 1227
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + L+E R + ++I + +LS+
Sbjct: 1228 EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK----NEEIQR---------SLSEL 1274
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
TT +LQ E L + QL + + F ++E N
Sbjct: 1275 TTQKSRLQTEAGELSRQLEEKESIVSQLSRS------KQAFTQQTEELKRQLEEENKAKN 1328
Query: 605 -VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE-KRIVDVDTQIKTLN 662
+ L+ D + +E K+ ++ + ++E+ Q K D + + L
Sbjct: 1329 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 1388
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E E++ L + E+++ + ++ L++ Q ++ V++ DV+ +L
Sbjct: 1389 EAQEKLAQRLQDSEEQV---EAVNAKCASLEKTKQRLQ------GEVEDLMVDVERANSL 1439
Query: 723 DVA-TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
A KQ +F + ++ + + + +Q +L A K+ ++L + K K ++ + +
Sbjct: 1440 AAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAY---EEALDQL 1496
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGS 838
++ K L+ + I LE + K+ K ++ + +E
Sbjct: 1497 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEE 1556
Query: 839 AYIAKVEVAFNKVKS--------LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
A I ++++ +VKS D EI+Q K+N R +E +Q A D + + + +
Sbjct: 1557 AKILRIQLELTQVKSEIDRKIAEKDEEIEQ-LKRNYQRTVETMQSALDAEVRSRNEAIRL 1615
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
++ + ++ + EI ++ + LR Q + + Q L++ L G +E+L
Sbjct: 1616 KKKMEGDLNEI--EIQLSHANRQAAETLKHLRSVQGQLKDTQL---HLDDALRG--QEDL 1668
Query: 951 NEKESLIIKQTKLFQQKA-ECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
E+ +++ ++ L Q + E L + +++ K EL S ++ ++ + +H
Sbjct: 1669 KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NERVQLLHTQNTSLIHT 1727
Query: 1010 TKAIDKDIRE 1019
K ++ D+ +
Sbjct: 1728 KKKLETDLMQ 1737
Score = 54.0 bits (124), Expect = 3e-06
Identities = 130/686 (18%), Positives = 271/686 (39%), Gaps = 50/686 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIE-ENLKT 443
K AE E + ++E + + + + E + EL +K+ L ++ L+ + E ENL
Sbjct: 842 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLD 901
Query: 444 KEK---QLIVLKNKHKTALMELLGNVP-EKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
E+ QLI K + + + E+ E++ + + ++ +E
Sbjct: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E+ + EL+ ++ I K T+ + ++ LQ E++ +
Sbjct: 962 LAKVEKEKHATENKVKNLTEELSGLDETIAKL--TREKKALQEAHQQALDDLQAEEDKVN 1019
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
S +NK K +L+ E E + +++ K+ DL+ A
Sbjct: 1020 S----LNKTKSKLEQQ--VEDLESSLEQEKKLR----------VDLERNKRKLEGDLKLA 1063
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDT-------QIKTLNETVEEITMSL 672
++ + K ++ KD E QL+ ++ D T +IK L +EE+ +
Sbjct: 1064 QESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEI 1123
Query: 673 -IEPEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDVDSEMTLDVATA 727
E + T KQ ++ L ++E VT + E K++ + ++ D+ A
Sbjct: 1124 EAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEF-LKLRRDLEEA 1182
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEE 786
+ + ++TLR + + +L LQ + +K K K E L + ++ +
Sbjct: 1183 -TLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSK 1241
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKE----KIEAKTEVVRRNRDLIEAGS--AY 840
SK L+ C ++ +L E K +TE +R L E S +
Sbjct: 1242 SKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQ 1301
Query: 841 IAKVEVAF-NKVKSLDAEI-QQHKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
+++ + AF + + L ++ +++K KN + ++ + D L E+ ++ + L +
Sbjct: 1302 LSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRA 1361
Query: 898 IDTLKDEIAK-QEVYKRD-LDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
+ E+A+ + Y+ D + L +AQ + + +E E +N K+
Sbjct: 1362 LSKANSEVAQWRTKYETDAIQRTEELEEAQEKLAQRLQDSEEQVEAVNAKCASLEKTKQR 1421
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L + L + L K + F L + +K E+ E L ++++
Sbjct: 1422 LQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTK-CEESQAELEASLKESRSLST 1480
Query: 1016 DIREYAVALDKCLMEFHREKMENINM 1041
++ + A ++ L + K EN N+
Sbjct: 1481 ELFKLKNAYEEALDQLETVKRENKNL 1506
Score = 46.4 bits (105), Expect = 6e-04
Identities = 40/164 (24%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD 936
K+ K T++++ T K KDE+AK E +++L++ L + + Q Q +
Sbjct: 836 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAE 895
Query: 937 ELN-----EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
N E+ + + K + + E+ I + T+ + + E L+ K+ L+ +EL+K
Sbjct: 896 SENLLDAEERCDQLIKAKF-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 954
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + E H T+ K++ E LD+ + + REK
Sbjct: 955 ID-DLELTLAKVEKEKHATENKVKNLTEELSGLDETIAKLTREK 997
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 68.1 bits (159), Expect = 2e-10
Identities = 163/978 (16%), Positives = 378/978 (38%), Gaps = 68/978 (6%)
Query: 81 QVKLKIVNAKDKQLEVTRSM--KVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADL 138
Q ++++V++ +Q ++ R + + T +A D L++ + T S A +
Sbjct: 598 QHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPV 657
Query: 139 DILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIR 198
++ E +KA L + + + K E+ +++ ++ +D + KI
Sbjct: 658 PVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKL--QEQVTDLRSQNTKIS 715
Query: 199 KDYAQNLKLLENYATTVKAKQKELEDSYKKN---TSFNKEEEKIANEKSSNEIEYNKFIL 255
K E V+ ++E+ +++N T+ +++E+I N + + N+ +
Sbjct: 716 TQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLA 775
Query: 256 LESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ-K 314
+ E + K+ +++++ +++ + + + +N T L+ ++ + + + K
Sbjct: 776 VAEVRAENL-KKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETK 834
Query: 315 SQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXX 374
+ + +K + + + + +
Sbjct: 835 QRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELL 894
Query: 375 XXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK 434
KQ + + ++ Q K ++++D+L ++ + ++Q LKE+
Sbjct: 895 KNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKER 954
Query: 435 EMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXX 494
+ ++ Q +V T+L E L EK + K EV
Sbjct: 955 -LKTSTSNVEQYQAMV------TSLEESLNK--EKQVTEEVRK-----NIEVRLKESAEF 1000
Query: 495 XXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTV-EKLQD 553
+E E++ +E +++R + E ++ + TLS V E LQ
Sbjct: 1001 QTQLEKKLMEVEKEK-QELQDDKRRAIESMEQQLSEL------KKTLSSVQNEVQEALQR 1053
Query: 554 EQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
L + + Q K +E E K+ V
Sbjct: 1054 ASTALSNEQQARRDCQEQAK---IAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVR 1110
Query: 614 EDLQRASAKKD-EILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS 671
+ L+ + K + ++L K S E+ LKD E+ + R D++ Q + L++ +E+++
Sbjct: 1111 QHLEETTQKAESQLLECKASWEERERMLKD-EVSKCVCRCEDLEKQNRLLHDQIEKLSDK 1169
Query: 672 LIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD 731
++ K ++ + + ++I + + KE +E +VA + +
Sbjct: 1170 VVA-SVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEI-----AETRFEVAQVESLR 1223
Query: 732 FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-----NLEE 786
++Q++ L ++ Q LNA +K+Q KT A+ E L + + ++V L E
Sbjct: 1224 YRQRVELLERELQELQDSLNAEREKVQV--TAKTMAQHEELMKKTETMNVVMETNKMLRE 1281
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG-SAYIAKVE 845
K++L+ D I PL+ A E + K+ +++ + L+E + A+ +
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAE-LSEKSGMLQAEKKLLEEDVKRWKARNQ 1340
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK---IDTLK 902
++ K D E + ++IQ+ +++ + +I LT I +LK
Sbjct: 1341 HLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Query: 903 DEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK 962
+++ K K + +L I + Q++ + + + I + + E L +Q K
Sbjct: 1401 EDLNKVRTEKETIQKDL-----DAKIIDIQEKVKTITQ-VKKIGRRYKTQYEELKAQQDK 1454
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEKSL------SKDIEKKFREKMYELHVTKAIDKD 1016
+ + A+ +G E S++ + EL+++L SK +E + L + ++
Sbjct: 1455 VMETSAQSSGDHQEQHVSVQEMQ-ELKETLNQAETKSKSLESQVENLQKTLSEKETEARN 1513
Query: 1017 IREYAVALDKCLMEFHRE 1034
++E V L L ++
Sbjct: 1514 LQEQTVQLQSELSRLRQD 1531
Score = 47.6 bits (108), Expect = 3e-04
Identities = 91/434 (20%), Positives = 192/434 (44%), Gaps = 51/434 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
KLE+ +++QR D+ S+ E+ + ++E ++ D+ QI+ L +EE
Sbjct: 457 KLEQAMKEIQRLQEDTDKANKQSSVLER-------DNRRMEIQVKDLSQQIRVLLMELEE 509
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + ++++++A I ++ +++ + + E +++Q + + + +
Sbjct: 510 ARGNHVIRDEEVSSA-DISSSSEVISQHLVSYRNI----EELQQQ----NQRLLVALREL 560
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ +++ T +++ Q KL + +L+ L K + + +L+++ + +D+ + S
Sbjct: 561 GETREREEQETTSSKITELQLKLESALTELEQL-RKSRQHQMQLVDSIVRQRDMYRILLS 619
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV-VRRNRDLIEAGSAYIAKVEV 846
+ + A TP + + + V V + + IEA +A + +++
Sbjct: 620 QTTGVA-IPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAA-LKQLQE 677
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
F K AE K +N ++EK+QE L + +I T +K+ + L+D +
Sbjct: 678 IFENYKKEKAE--NEKIQN--EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNV- 732
Query: 907 KQEVYKRDL----DDNLCL---RKAQTDITNWQKQD-DELNEKL--NGINKEEL-NEKES 955
E Y+R++ + N L + Q I N QD NEKL + E L EKE
Sbjct: 733 --EGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEM 790
Query: 956 LIIKQTKLFQQK----AECTGA------LSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
L + + +L QQ+ AE G L ++ L+ E ++ LS IEK E
Sbjct: 791 LKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEIS- 849
Query: 1006 ELHVTKAIDKDIRE 1019
H+ K ++ ++ +
Sbjct: 850 --HLKKKLENEVEQ 861
Score = 47.2 bits (107), Expect = 4e-04
Identities = 113/654 (17%), Positives = 260/654 (39%), Gaps = 64/654 (9%)
Query: 386 QAENEL-NIEECQQEINEDEK-AVEQYEQEMDELSQKITK--------LQKQTAKLKEKE 435
Q E +L +E+ +QE+ +D++ A+E EQ++ EL + ++ LQ+ + L ++
Sbjct: 1003 QLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQ 1062
Query: 436 MIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXX 495
+ + + K + +NK++ LM +V A VR +
Sbjct: 1063 QARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAES 1122
Query: 496 XXXXXXXLEAERKHIR-----------ESLNERR----SELTKAEDKIYKAC--GTQ-PY 537
ER+ + E L ++ ++ K DK+ + G Q P
Sbjct: 1123 QLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPL 1182
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
+V+LS E+ + ++ +L+ FI + + + + + E
Sbjct: 1183 NVSLS------EEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQ 1236
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQ 657
+N + +VT + A+ +E+ MK ++ ++ + EK ++ D Q
Sbjct: 1237 ELQDSLNAEREKVQVTA---KTMAQHEEL--MKKTETMNVVMETNKMLREEKERLEQDLQ 1291
Query: 658 IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDV 716
+ V ++ + ++ ++ + G + + ++E +K + + + Q D
Sbjct: 1292 --QMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDP 1349
Query: 717 DSEMTLDVATAKQVDFK------QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
D+E + + K+V K ++I L+ + + L + +Q+L E K + E
Sbjct: 1350 DTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTE 1409
Query: 771 LLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR 829
QK + I++++E K + + ++ ++ + +
Sbjct: 1410 KETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQ 1469
Query: 830 NRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT 889
+ + E + A K KSL+++++ +K +E E + ++ ++ Q ++
Sbjct: 1470 HVSVQEMQELK-ETLNQAETKSKSLESQVENLQKTLSEKETEA-RNLQEQTVQLQSELSR 1527
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
RQ L + T ++E +Q++ +++ + A++ I + L G+ +
Sbjct: 1528 LRQDLQDR--TTQEEQLRQQITEKEEKTRKAIVAAKSKIAH-----------LAGVKDQL 1574
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
E E L + L QQK E ++ LK +G + LE+ L + E+ ++
Sbjct: 1575 TKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQR 1628
Score = 44.4 bits (100), Expect = 0.002
Identities = 80/444 (18%), Positives = 191/444 (43%), Gaps = 21/444 (4%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LEK+ L+ + K E+ + N I + +LE D+ + L++ +E
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEY 140
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+T + +K+ + G++ + +Q K E EQ ++ + T
Sbjct: 141 LTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTE 200
Query: 728 KQVDFKQKISTLRNR-VKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ + ++ R + + + K N NKK + L E+ K + QK V+D++
Sbjct: 201 LKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK 260
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR-----NRDLIEAGSA 839
+ K+ Q+ ++ L + + EAK+ + R ++ L EAG A
Sbjct: 261 LKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEA 320
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL-MEKQKQIMTDRQVLTKKI 898
A ++ +V+ ++++ + + R ++++ AND L K+K + + L
Sbjct: 321 NKA-IQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 899 DTLK--DEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
T +I K + +L + + Q + + ++ +N+ L+ I K E+ K +
Sbjct: 380 PTAAAVAKIVKPGMKLTELYN--AYVETQDQLLLEKLENKRINKYLDEIVK-EVEAKAPI 436
Query: 957 IIKQTKLFQQKAECTGALS-ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+ +Q + +++ + +LS +L++++K E+++ L +D +K ++ + ++
Sbjct: 437 LKRQREEYERAQKAVASLSVKLEQAMK----EIQR-LQEDTDKANKQSSVLERDNRRMEI 491
Query: 1016 DIREYAVALDKCLMEFHREKMENI 1039
+++ + + LME + ++
Sbjct: 492 QVKDLSQQIRVLLMELEEARGNHV 515
Score = 44.0 bits (99), Expect = 0.003
Identities = 71/349 (20%), Positives = 147/349 (42%), Gaps = 33/349 (9%)
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT 759
K ++ E ++EQ D+ S+ T ++T Q+DF K R + Q + + +++ +
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNT-KIST--QLDFASK------RYEMLQDNVEGYRREITS 741
Query: 760 LYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEK 819
L+E+ K L T +K + I+N + D L+ KEK
Sbjct: 742 LHERNQK----LTATTQKQEQIINT------MTQDLRGANEKLAVAEVRAENLK---KEK 788
Query: 820 IEAKTEVVR--RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
K VR + R+ + A + ++ + + K+ + ++EK++
Sbjct: 789 EMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEI 848
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL--CLRKAQTDITNWQKQD 935
L +K + + R LT+ +D + +Q + +L N L+ AQ +I ++
Sbjct: 849 SHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHL 908
Query: 936 DELNEKLNGINKEELNEKESLIIKQTK-LFQQKAECTGALSELKKSLKGFRNELEK--SL 992
+ ++ + + + + + L Q + +++LK+ LK + +E+ ++
Sbjct: 909 SNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAM 968
Query: 993 SKDIEKKF-REKMYELHVTKAID---KDIREYAVALDKCLMEFHREKME 1037
+E+ +EK V K I+ K+ E+ L+K LME +EK E
Sbjct: 969 VTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQE 1017
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 68.1 bits (159), Expect = 2e-10
Identities = 163/978 (16%), Positives = 378/978 (38%), Gaps = 68/978 (6%)
Query: 81 QVKLKIVNAKDKQLEVTRSM--KVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADL 138
Q ++++V++ +Q ++ R + + T +A D L++ + T S A +
Sbjct: 598 QHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPV 657
Query: 139 DILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIR 198
++ E +KA L + + + K E+ +++ ++ +D + KI
Sbjct: 658 PVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKL--QEQVTDLRSQNTKIS 715
Query: 199 KDYAQNLKLLENYATTVKAKQKELEDSYKKN---TSFNKEEEKIANEKSSNEIEYNKFIL 255
K E V+ ++E+ +++N T+ +++E+I N + + N+ +
Sbjct: 716 TQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLA 775
Query: 256 LESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ-K 314
+ E + K+ +++++ +++ + + + +N T L+ ++ + + + K
Sbjct: 776 VAEVRAENL-KKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETK 834
Query: 315 SQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXX 374
+ + +K + + + + +
Sbjct: 835 QRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELL 894
Query: 375 XXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK 434
KQ + + ++ Q K ++++D+L ++ + ++Q LKE+
Sbjct: 895 KNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKER 954
Query: 435 EMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXX 494
+ ++ Q +V T+L E L EK + K EV
Sbjct: 955 -LKTSTSNVEQYQAMV------TSLEESLNK--EKQVTEEVRK-----NIEVRLKESAEF 1000
Query: 495 XXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTV-EKLQD 553
+E E++ +E +++R + E ++ + TLS V E LQ
Sbjct: 1001 QTQLEKKLMEVEKEK-QELQDDKRRAIESMEQQLSEL------KKTLSSVQNEVQEALQR 1053
Query: 554 EQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
L + + Q K +E E K+ V
Sbjct: 1054 ASTALSNEQQARRDCQEQAK---IAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVR 1110
Query: 614 EDLQRASAKKD-EILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS 671
+ L+ + K + ++L K S E+ LKD E+ + R D++ Q + L++ +E+++
Sbjct: 1111 QHLEETTQKAESQLLECKASWEERERMLKD-EVSKCVCRCEDLEKQNRLLHDQIEKLSDK 1169
Query: 672 LIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD 731
++ K ++ + + ++I + + KE +E +VA + +
Sbjct: 1170 VVA-SVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEI-----AETRFEVAQVESLR 1223
Query: 732 FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-----NLEE 786
++Q++ L ++ Q LNA +K+Q KT A+ E L + + ++V L E
Sbjct: 1224 YRQRVELLERELQELQDSLNAEREKVQV--TAKTMAQHEELMKKTETMNVVMETNKMLRE 1281
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG-SAYIAKVE 845
K++L+ D I PL+ A E + K+ +++ + L+E + A+ +
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAE-LSEKSGMLQAEKKLLEEDVKRWKARNQ 1340
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK---IDTLK 902
++ K D E + ++IQ+ +++ + +I LT I +LK
Sbjct: 1341 HLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Query: 903 DEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK 962
+++ K K + +L I + Q++ + + + I + + E L +Q K
Sbjct: 1401 EDLNKVRTEKETIQKDL-----DAKIIDIQEKVKTITQ-VKKIGRRYKTQYEELKAQQDK 1454
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEKSL------SKDIEKKFREKMYELHVTKAIDKD 1016
+ + A+ +G E S++ + EL+++L SK +E + L + ++
Sbjct: 1455 VMETSAQSSGDHQEQHVSVQEMQ-ELKETLNQAETKSKSLESQVENLQKTLSEKETEARN 1513
Query: 1017 IREYAVALDKCLMEFHRE 1034
++E V L L ++
Sbjct: 1514 LQEQTVQLQSELSRLRQD 1531
Score = 47.6 bits (108), Expect = 3e-04
Identities = 91/434 (20%), Positives = 192/434 (44%), Gaps = 51/434 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
KLE+ +++QR D+ S+ E+ + ++E ++ D+ QI+ L +EE
Sbjct: 457 KLEQAMKEIQRLQEDTDKANKQSSVLER-------DNRRMEIQVKDLSQQIRVLLMELEE 509
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + ++++++A I ++ +++ + + E +++Q + + + +
Sbjct: 510 ARGNHVIRDEEVSSA-DISSSSEVISQHLVSYRNI----EELQQQ----NQRLLVALREL 560
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ +++ T +++ Q KL + +L+ L K + + +L+++ + +D+ + S
Sbjct: 561 GETREREEQETTSSKITELQLKLESALTELEQL-RKSRQHQMQLVDSIVRQRDMYRILLS 619
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV-VRRNRDLIEAGSAYIAKVEV 846
+ + A TP + + + V V + + IEA +A + +++
Sbjct: 620 QTTGVA-IPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAA-LKQLQE 677
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
F K AE K +N ++EK+QE L + +I T +K+ + L+D +
Sbjct: 678 IFENYKKEKAE--NEKIQN--EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNV- 732
Query: 907 KQEVYKRDL----DDNLCL---RKAQTDITNWQKQD-DELNEKL--NGINKEEL-NEKES 955
E Y+R++ + N L + Q I N QD NEKL + E L EKE
Sbjct: 733 --EGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEM 790
Query: 956 LIIKQTKLFQQK----AECTGA------LSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
L + + +L QQ+ AE G L ++ L+ E ++ LS IEK E
Sbjct: 791 LKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEIS- 849
Query: 1006 ELHVTKAIDKDIRE 1019
H+ K ++ ++ +
Sbjct: 850 --HLKKKLENEVEQ 861
Score = 47.2 bits (107), Expect = 4e-04
Identities = 113/654 (17%), Positives = 260/654 (39%), Gaps = 64/654 (9%)
Query: 386 QAENEL-NIEECQQEINEDEK-AVEQYEQEMDELSQKITK--------LQKQTAKLKEKE 435
Q E +L +E+ +QE+ +D++ A+E EQ++ EL + ++ LQ+ + L ++
Sbjct: 1003 QLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQ 1062
Query: 436 MIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXX 495
+ + + K + +NK++ LM +V A VR +
Sbjct: 1063 QARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAES 1122
Query: 496 XXXXXXXLEAERKHIR-----------ESLNERR----SELTKAEDKIYKAC--GTQ-PY 537
ER+ + E L ++ ++ K DK+ + G Q P
Sbjct: 1123 QLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPL 1182
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
+V+LS E+ + ++ +L+ FI + + + + + E
Sbjct: 1183 NVSLS------EEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQ 1236
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQ 657
+N + +VT + A+ +E+ MK ++ ++ + EK ++ D Q
Sbjct: 1237 ELQDSLNAEREKVQVTA---KTMAQHEEL--MKKTETMNVVMETNKMLREEKERLEQDLQ 1291
Query: 658 IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDV 716
+ V ++ + ++ ++ + G + + ++E +K + + + Q D
Sbjct: 1292 --QMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDP 1349
Query: 717 DSEMTLDVATAKQVDFK------QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
D+E + + K+V K ++I L+ + + L + +Q+L E K + E
Sbjct: 1350 DTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTE 1409
Query: 771 LLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR 829
QK + I++++E K + + ++ ++ + +
Sbjct: 1410 KETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQ 1469
Query: 830 NRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT 889
+ + E + A K KSL+++++ +K +E E + ++ ++ Q ++
Sbjct: 1470 HVSVQEMQELK-ETLNQAETKSKSLESQVENLQKTLSEKETEA-RNLQEQTVQLQSELSR 1527
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
RQ L + T ++E +Q++ +++ + A++ I + L G+ +
Sbjct: 1528 LRQDLQDR--TTQEEQLRQQITEKEEKTRKAIVAAKSKIAH-----------LAGVKDQL 1574
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
E E L + L QQK E ++ LK +G + LE+ L + E+ ++
Sbjct: 1575 TKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQR 1628
Score = 44.4 bits (100), Expect = 0.002
Identities = 80/444 (18%), Positives = 191/444 (43%), Gaps = 21/444 (4%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LEK+ L+ + K E+ + N I + +LE D+ + L++ +E
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEY 140
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+T + +K+ + G++ + +Q K E EQ ++ + T
Sbjct: 141 LTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTE 200
Query: 728 KQVDFKQKISTLRNR-VKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ + ++ R + + + K N NKK + L E+ K + QK V+D++
Sbjct: 201 LKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK 260
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR-----NRDLIEAGSA 839
+ K+ Q+ ++ L + + EAK+ + R ++ L EAG A
Sbjct: 261 LKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEA 320
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL-MEKQKQIMTDRQVLTKKI 898
A ++ +V+ ++++ + + R ++++ AND L K+K + + L
Sbjct: 321 NKA-IQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 899 DTLK--DEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
T +I K + +L + + Q + + ++ +N+ L+ I K E+ K +
Sbjct: 380 PTAAAVAKIVKPGMKLTELYN--AYVETQDQLLLEKLENKRINKYLDEIVK-EVEAKAPI 436
Query: 957 IIKQTKLFQQKAECTGALS-ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+ +Q + +++ + +LS +L++++K E+++ L +D +K ++ + ++
Sbjct: 437 LKRQREEYERAQKAVASLSVKLEQAMK----EIQR-LQEDTDKANKQSSVLERDNRRMEI 491
Query: 1016 DIREYAVALDKCLMEFHREKMENI 1039
+++ + + LME + ++
Sbjct: 492 QVKDLSQQIRVLLMELEEARGNHV 515
Score = 44.0 bits (99), Expect = 0.003
Identities = 71/349 (20%), Positives = 147/349 (42%), Gaps = 33/349 (9%)
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT 759
K ++ E ++EQ D+ S+ T ++T Q+DF K R + Q + + +++ +
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNT-KIST--QLDFASK------RYEMLQDNVEGYRREITS 741
Query: 760 LYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEK 819
L+E+ K L T +K + I+N + D L+ KEK
Sbjct: 742 LHERNQK----LTATTQKQEQIINT------MTQDLRGANEKLAVAEVRAENLK---KEK 788
Query: 820 IEAKTEVVR--RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
K VR + R+ + A + ++ + + K+ + ++EK++
Sbjct: 789 EMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEI 848
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL--CLRKAQTDITNWQKQD 935
L +K + + R LT+ +D + +Q + +L N L+ AQ +I ++
Sbjct: 849 SHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHL 908
Query: 936 DELNEKLNGINKEELNEKESLIIKQTK-LFQQKAECTGALSELKKSLKGFRNELEK--SL 992
+ ++ + + + + + L Q + +++LK+ LK + +E+ ++
Sbjct: 909 SNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAM 968
Query: 993 SKDIEKKF-REKMYELHVTKAID---KDIREYAVALDKCLMEFHREKME 1037
+E+ +EK V K I+ K+ E+ L+K LME +EK E
Sbjct: 969 VTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQE 1017
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 67.7 bits (158), Expect = 2e-10
Identities = 169/901 (18%), Positives = 365/901 (40%), Gaps = 84/901 (9%)
Query: 101 KVTALAKKKTKF-QTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFC 159
KV +L K K+K Q ++ S++++ K + DL+ + G K S++
Sbjct: 162 KVNSLNKTKSKLEQQVEDLESSLEQEKKLR------VDLERNKRKLEGDLKLAQESIL-- 213
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSD----CLDRLKKIRKDYAQNLKLLENYAT-- 213
E+ LDE K K+ F+ K D L KKI++ A+ +L E
Sbjct: 214 DLENDKQQLDERLKKKD-FEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 272
Query: 214 TVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK-----FILLESQNQEKIDKRN 268
+AK ++ Y + E + A +S +IE NK F+ L ++ E+ ++
Sbjct: 273 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLR-RDLEEATLQH 331
Query: 269 EQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ---KSQADEEEKKAQ 325
E +V T + +++ E+ E+ +N + + +K+E KS+ K++ S + E K++
Sbjct: 332 EAMVATLRKKHADSVAEL--GEQIDNLQR-VKQKLEKEKSEFKLEIDDLSSSMESVSKSK 388
Query: 326 GFVDE-CRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXX--X 382
+++ CR+ Q ++
Sbjct: 389 ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLS 448
Query: 383 XHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE-KEMIEENL 441
KQA + EE ++++ E+ KA + L++Q + +E K ++ L
Sbjct: 449 RSKQAFTQ-QTEELKRQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKAELQRAL 507
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
++ + K++T ++ + E + + E +V
Sbjct: 508 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSE--EQVEAVNAKCASLEKTKQ 565
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQ-------DE 554
L+ E + + + ER + L A DK + +D L+++ T E+ Q E
Sbjct: 566 RLQGEVEDLMVDV-ERANSLAAALDKKQRN-----FDKVLAEWKTKCEESQAELEASLKE 619
Query: 555 QNVLQSSMFII-NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
L + +F + N Y+ L N+ E E ++ K K
Sbjct: 620 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 679
Query: 614 E----DLQRASAKKDEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNE----T 664
E D+Q A + + L + L+ T++ +++++I + D +I+ L T
Sbjct: 680 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRT 739
Query: 665 VEEITMSLIEPEQKMTTA----KQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDV-DS 718
VE + +L ++ A K++ GD+ ++ + + + + ++ G + D+
Sbjct: 740 VETMQSALDAEVRRANEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 799
Query: 719 EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
++ LD A Q D K++++ + R Q ++ L+ + A++ELL++ ++V
Sbjct: 800 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 859
Query: 779 QDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI---EAKTEVVRRNR 831
Q + +L +KK+L++D E K+ I E +++ +
Sbjct: 860 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 919
Query: 832 DLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
D SA++ +++ + VK L + + ++ + ++IQ+ ++ E + ++ +
Sbjct: 920 DT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 975
Query: 891 RQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCLR------KAQTDITNWQKQDDELNEKL 942
++ T+ + L+ + K+ Y+ + D LR K Q + ++++Q +E +E+
Sbjct: 976 QKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQA 1035
Query: 943 N 943
N
Sbjct: 1036 N 1036
Score = 59.7 bits (138), Expect = 6e-08
Identities = 126/670 (18%), Positives = 271/670 (40%), Gaps = 75/670 (11%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQK------ITKLQKQTAKL 431
K E + IEE ++EI + EK Y +E++ELS++ +T Q + K
Sbjct: 253 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 312
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E + L+ KH ++ EL + + + K + E +
Sbjct: 313 REAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 372
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + L+E R + ++I + +LS+
Sbjct: 373 EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK----NEEIQR---------SLSEL 419
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
TT +LQ E L + QL + + F ++E N
Sbjct: 420 TTQKSRLQTEAGELSRQLEEKESIVSQLSRS------KQAFTQQTEELKRQLEEENKAKN 473
Query: 605 VPG-KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE-KRIVDVDTQIKTLN 662
G L+ D + +E K+ ++ + ++E+ Q K D + + L
Sbjct: 474 ALGHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 533
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E +++ L + E+++ + ++ L++ Q ++ V++ DV+ +L
Sbjct: 534 EAKKKLAQRLQDSEEQV---EAVNAKCASLEKTKQRLQ------GEVEDLMVDVERANSL 584
Query: 723 DVA-TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
A KQ +F + ++ + + + +Q +L A K+ ++L + K K ++ + +
Sbjct: 585 AAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAY---EEALDQL 641
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGS 838
++ K L+ + I LE + K+ K ++ + +E
Sbjct: 642 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEE 701
Query: 839 AYIAKVEVAFNKVKS--------LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
A I ++++ +VKS D EI+Q K+N R +E +Q A D + + + +
Sbjct: 702 AKILRIQLELTQVKSEIDRKIAEKDEEIEQ-LKRNYQRTVETMQSALDAEVRRANEAIRL 760
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
++ + ++ + EI ++ + LR Q + + Q L++ L G +E+L
Sbjct: 761 KKKMEGDLNEI--EIQLSHANRQAAETLKHLRSVQGQLKDTQL---HLDDALRG--QEDL 813
Query: 951 NEKESLIIKQTKLFQQKA-ECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
E+ +++ ++ L Q + E L + +++ K EL S ++ ++ + +H
Sbjct: 814 KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NERVQLLHTQNTSLIHT 872
Query: 1010 TKAIDKDIRE 1019
K ++ D+ +
Sbjct: 873 KKKLETDLMQ 882
Score = 44.8 bits (101), Expect = 0.002
Identities = 108/567 (19%), Positives = 228/567 (40%), Gaps = 32/567 (5%)
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVT--LSKYTTTVEKLQDEQNVLQS 560
LE E +++ +++ L K E + + A + ++T LS T+ KL E+ LQ
Sbjct: 89 LEDECSELKKDIDDLELTLAKVEKEKH-ATENKVKNLTEELSGLDETIAKLTREKKALQE 147
Query: 561 S--MFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
+ + + + K NS ++ + + +++ K+ DL+
Sbjct: 148 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKL 207
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDT-------QIKTLNETVEEITMS 671
A ++ + K ++ KD E QL+ ++ D T +IK L +EE+
Sbjct: 208 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 267
Query: 672 L-IEPEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDVDSEMTLDVAT 726
+ E + T KQ ++ L ++E VT + E K++ + ++ D+
Sbjct: 268 IEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEF-LKLRRDLEE 326
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLE 785
A + + ++TLR + + +L LQ + +K K K E L + ++
Sbjct: 327 A-TLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 385
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE----KIEAKTEVVRRNRDLIEAGS--A 839
+SK L+ C ++ +L E K +TE +R L E S +
Sbjct: 386 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVS 445
Query: 840 YIAKVEVAF-NKVKSLDAEI-QQHKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+++ + AF + + L ++ +++K KN + ++ + D L E+ ++ + L +
Sbjct: 446 QLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRHDCDLLREQYEEEQEGKAELQR 505
Query: 897 KIDTLKDEIAK-QEVYKRD-LDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKE 954
+ E+A+ + Y+ D + L +A+ + + +E E +N K+
Sbjct: 506 ALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQ 565
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
L + L + L K + F L + +K E+ E L ++++
Sbjct: 566 RLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTK-CEESQAELEASLKESRSLS 624
Query: 1015 KDIREYAVALDKCLMEFHREKMENINM 1041
++ + A ++ L + K EN N+
Sbjct: 625 TELFKLKNAYEEALDQLETVKRENKNL 651
Score = 43.2 bits (97), Expect = 0.006
Identities = 35/139 (25%), Positives = 68/139 (48%), Gaps = 7/139 (5%)
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN-----EKLNGINKEELNEKESL 956
KDE+AK E +++L++ L + + Q Q + N E+ + + K + + E+
Sbjct: 6 KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKF-QLEAK 64
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
I + T+ + + E L+ K+ L+ +EL+K + D+E + E H T+ K+
Sbjct: 65 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID-DLELTLAKVEKEKHATENKVKN 123
Query: 1017 IREYAVALDKCLMEFHREK 1035
+ E LD+ + + REK
Sbjct: 124 LTEELSGLDETIAKLTREK 142
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 67.7 bits (158), Expect = 2e-10
Identities = 167/901 (18%), Positives = 364/901 (40%), Gaps = 84/901 (9%)
Query: 101 KVTALAKKKTKF-QTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFC 159
KV +L K K+K Q ++ S++++ K + DL+ + G K S++
Sbjct: 162 KVNSLNKTKSKLEQQVEDLESSLEQEKKLR------VDLERNKRKLEGDLKLAQESIL-- 213
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSD----CLDRLKKIRKDYAQNLKLLENYAT-- 213
E+ LDE K K+ F+ K D L KKI++ A+ +L E
Sbjct: 214 DLENDKQQLDERLKKKD-FEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 272
Query: 214 TVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK-----FILLESQNQEKIDKRN 268
+AK ++ Y + E + A +S +IE NK F+ L ++ E+ ++
Sbjct: 273 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLR-RDLEEATLQH 331
Query: 269 EQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ---KSQADEEEKKAQ 325
E +V T + +++ E+ E+ +N + + +K+E KS+ K++ S + E K++
Sbjct: 332 EAMVATLRKKHADSVAEL--GEQIDNLQR-VKQKLEKEKSEFKLEIDDLSSSMESVSKSK 388
Query: 326 GFVDE-CRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXX--X 382
+++ CR+ Q ++
Sbjct: 389 ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLS 448
Query: 383 XHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE-KEMIEENL 441
KQA + EE ++++ E+ KA + L++Q + +E K ++ L
Sbjct: 449 RSKQAFTQ-QTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 507
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
++ + K++T ++ + E + + E +V
Sbjct: 508 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSE--EQVEAVNAKCASLEKTKQ 565
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQ-------DE 554
L+ E + + + ER + L A DK + +D L+++ T E+ Q E
Sbjct: 566 RLQGEVEDLMVDV-ERANSLAAALDKKQRN-----FDKVLAEWKTKCEESQAELEASLKE 619
Query: 555 QNVLQSSMFII-NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
L + +F + N Y+ L N+ E E ++ K K
Sbjct: 620 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 679
Query: 614 E----DLQRASAKKDEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNETVE-- 666
E D+Q A + + L + L+ T++ +++++I + D +I+ L +
Sbjct: 680 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRT 739
Query: 667 -EITMSLIEPE-----QKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDV-DS 718
E S ++ E + + K++ GD+ ++ + + + + ++ G + D+
Sbjct: 740 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 799
Query: 719 EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
++ LD A Q D K++++ + R Q ++ L+ + A++ELL++ ++V
Sbjct: 800 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 859
Query: 779 QDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI---EAKTEVVRRNR 831
Q + +L +KK+L++D E K+ I E +++ +
Sbjct: 860 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 919
Query: 832 DLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
D SA++ +++ + VK L + + ++ + ++IQ+ ++ E + ++ +
Sbjct: 920 DT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 975
Query: 891 RQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCLR------KAQTDITNWQKQDDELNEKL 942
++ T+ + L+ + K+ Y+ + D LR K Q + ++++Q +E +E+
Sbjct: 976 QKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQA 1035
Query: 943 N 943
N
Sbjct: 1036 N 1036
Score = 57.6 bits (133), Expect = 3e-07
Identities = 125/670 (18%), Positives = 271/670 (40%), Gaps = 75/670 (11%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQK------ITKLQKQTAKL 431
K E + IEE ++EI + EK Y +E++ELS++ +T Q + K
Sbjct: 253 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 312
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E + L+ KH ++ EL + + + K + E +
Sbjct: 313 REAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 372
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + L+E R + ++I + +LS+
Sbjct: 373 EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK----NEEIQR---------SLSEL 419
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
TT +LQ E L + QL + + F ++E N
Sbjct: 420 TTQKSRLQTEAGELSRQLEEKESIVSQLSRS------KQAFTQQTEELKRQLEEENKAKN 473
Query: 605 -VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE-KRIVDVDTQIKTLN 662
+ L+ D + +E K+ ++ + ++E+ Q K D + + L
Sbjct: 474 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 533
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E +++ L + E+++ + ++ L++ Q ++ V++ DV+ +L
Sbjct: 534 EAKKKLAQRLQDSEEQV---EAVNAKCASLEKTKQRLQ------GEVEDLMVDVERANSL 584
Query: 723 DVA-TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
A KQ +F + ++ + + + +Q +L A K+ ++L + K K ++ + +
Sbjct: 585 AAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAY---EEALDQL 641
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGS 838
++ K L+ + I LE + K+ K ++ + +E
Sbjct: 642 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEE 701
Query: 839 AYIAKVEVAFNKVKS--------LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
A I ++++ +VKS D EI+Q K+N R +E +Q A D + + + +
Sbjct: 702 AKILRIQLELTQVKSEIDRKIAEKDEEIEQ-LKRNYQRTVETMQSALDAEVRSRNEAIRL 760
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
++ + ++ + EI ++ + LR Q + + Q L++ L G +E+L
Sbjct: 761 KKKMEGDLNEI--EIQLSHANRQAAETLKHLRSVQGQLKDTQL---HLDDALRG--QEDL 813
Query: 951 NEKESLIIKQTKLFQQKA-ECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
E+ +++ ++ L Q + E L + +++ K EL S ++ ++ + +H
Sbjct: 814 KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NERVQLLHTQNTSLIHT 872
Query: 1010 TKAIDKDIRE 1019
K ++ D+ +
Sbjct: 873 KKKLETDLMQ 882
Score = 45.2 bits (102), Expect = 0.001
Identities = 108/567 (19%), Positives = 228/567 (40%), Gaps = 32/567 (5%)
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVT--LSKYTTTVEKLQDEQNVLQS 560
LE E +++ +++ L K E + + A + ++T LS T+ KL E+ LQ
Sbjct: 89 LEDECSELKKDIDDLELTLAKVEKEKH-ATENKVKNLTEELSGLDETIAKLTREKKALQE 147
Query: 561 S--MFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
+ + + + K NS ++ + + +++ K+ DL+
Sbjct: 148 AHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKL 207
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDT-------QIKTLNETVEEITMS 671
A ++ + K ++ KD E QL+ ++ D T +IK L +EE+
Sbjct: 208 AQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEE 267
Query: 672 L-IEPEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDVDSEMTLDVAT 726
+ E + T KQ ++ L ++E VT + E K++ + ++ D+
Sbjct: 268 IEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEF-LKLRRDLEE 326
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLE 785
A + + ++TLR + + +L LQ + +K K K E L + ++
Sbjct: 327 A-TLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVS 385
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE----KIEAKTEVVRRNRDLIEAGS--A 839
+SK L+ C ++ +L E K +TE +R L E S +
Sbjct: 386 KSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVS 445
Query: 840 YIAKVEVAF-NKVKSLDAEI-QQHKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+++ + AF + + L ++ +++K KN + ++ + D L E+ ++ + L +
Sbjct: 446 QLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQR 505
Query: 897 KIDTLKDEIAK-QEVYKRD-LDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKE 954
+ E+A+ + Y+ D + L +A+ + + +E E +N K+
Sbjct: 506 ALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQ 565
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
L + L + L K + F L + +K E+ E L ++++
Sbjct: 566 RLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTK-CEESQAELEASLKESRSLS 624
Query: 1015 KDIREYAVALDKCLMEFHREKMENINM 1041
++ + A ++ L + K EN N+
Sbjct: 625 TELFKLKNAYEEALDQLETVKRENKNL 651
Score = 43.2 bits (97), Expect = 0.006
Identities = 35/139 (25%), Positives = 68/139 (48%), Gaps = 7/139 (5%)
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN-----EKLNGINKEELNEKESL 956
KDE+AK E +++L++ L + + Q Q + N E+ + + K + + E+
Sbjct: 6 KDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKF-QLEAK 64
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
I + T+ + + E L+ K+ L+ +EL+K + D+E + E H T+ K+
Sbjct: 65 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID-DLELTLAKVEKEKHATENKVKN 123
Query: 1017 IREYAVALDKCLMEFHREK 1035
+ E LD+ + + REK
Sbjct: 124 LTEELSGLDETIAKLTREK 142
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 67.7 bits (158), Expect = 2e-10
Identities = 167/901 (18%), Positives = 364/901 (40%), Gaps = 84/901 (9%)
Query: 101 KVTALAKKKTKF-QTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFC 159
KV +L K K+K Q ++ S++++ K + DL+ + G K S++
Sbjct: 18 KVNSLNKTKSKLEQQVEDLESSLEQEKKLR------VDLERNKRKLEGDLKLAQESIL-- 69
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSD----CLDRLKKIRKDYAQNLKLLENYAT-- 213
E+ LDE K K+ F+ K D L KKI++ A+ +L E
Sbjct: 70 DLENDKQQLDERLKKKD-FEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 128
Query: 214 TVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK-----FILLESQNQEKIDKRN 268
+AK ++ Y + E + A +S +IE NK F+ L ++ E+ ++
Sbjct: 129 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLR-RDLEEATLQH 187
Query: 269 EQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ---KSQADEEEKKAQ 325
E +V T + +++ E+ E+ +N + + +K+E KS+ K++ S + E K++
Sbjct: 188 EAMVATLRKKHADSVAEL--GEQIDNLQR-VKQKLEKEKSEFKLEIDDLSSSMESVSKSK 244
Query: 326 GFVDE-CRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXX--X 382
+++ CR+ Q ++
Sbjct: 245 ANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLS 304
Query: 383 XHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE-KEMIEENL 441
KQA + EE ++++ E+ KA + L++Q + +E K ++ L
Sbjct: 305 RSKQAFTQ-QTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRAL 363
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
++ + K++T ++ + E + + E +V
Sbjct: 364 SKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSE--EQVEAVNAKCASLEKTKQ 421
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQ-------DE 554
L+ E + + + ER + L A DK + +D L+++ T E+ Q E
Sbjct: 422 RLQGEVEDLMVDV-ERANSLAAALDKKQRN-----FDKVLAEWKTKCEESQAELEASLKE 475
Query: 555 QNVLQSSMFII-NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
L + +F + N Y+ L N+ E E ++ K K
Sbjct: 476 SRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQI 535
Query: 614 E----DLQRASAKKDEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNETVE-- 666
E D+Q A + + L + L+ T++ +++++I + D +I+ L +
Sbjct: 536 ELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRT 595
Query: 667 -EITMSLIEPE-----QKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDV-DS 718
E S ++ E + + K++ GD+ ++ + + + + ++ G + D+
Sbjct: 596 VETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDT 655
Query: 719 EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
++ LD A Q D K++++ + R Q ++ L+ + A++ELL++ ++V
Sbjct: 656 QLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDSNERV 715
Query: 779 QDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI---EAKTEVVRRNR 831
Q + +L +KK+L++D E K+ I E +++ +
Sbjct: 716 QLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEELKKEQ 775
Query: 832 DLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
D SA++ +++ + VK L + + ++ + ++IQ+ ++ E + ++ +
Sbjct: 776 DT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 831
Query: 891 RQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCLR------KAQTDITNWQKQDDELNEKL 942
++ T+ + L+ + K+ Y+ + D LR K Q + ++++Q +E +E+
Sbjct: 832 QKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQA 891
Query: 943 N 943
N
Sbjct: 892 N 892
Score = 57.6 bits (133), Expect = 3e-07
Identities = 125/670 (18%), Positives = 271/670 (40%), Gaps = 75/670 (11%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQK------ITKLQKQTAKL 431
K E + IEE ++EI + EK Y +E++ELS++ +T Q + K
Sbjct: 109 KIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKK 168
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E + L+ KH ++ EL + + + K + E +
Sbjct: 169 REAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 228
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + L+E R + ++I + +LS+
Sbjct: 229 EIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGK----NEEIQR---------SLSEL 275
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
TT +LQ E L + QL + + F ++E N
Sbjct: 276 TTQKSRLQTEAGELSRQLEEKESIVSQLSRS------KQAFTQQTEELKRQLEEENKAKN 329
Query: 605 -VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE-KRIVDVDTQIKTLN 662
+ L+ D + +E K+ ++ + ++E+ Q K D + + L
Sbjct: 330 ALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELE 389
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E +++ L + E+++ + ++ L++ Q ++ V++ DV+ +L
Sbjct: 390 EAKKKLAQRLQDSEEQV---EAVNAKCASLEKTKQRLQ------GEVEDLMVDVERANSL 440
Query: 723 DVA-TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
A KQ +F + ++ + + + +Q +L A K+ ++L + K K ++ + +
Sbjct: 441 AAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAY---EEALDQL 497
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGS 838
++ K L+ + I LE + K+ K ++ + +E
Sbjct: 498 ETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEE 557
Query: 839 AYIAKVEVAFNKVKS--------LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
A I ++++ +VKS D EI+Q K+N R +E +Q A D + + + +
Sbjct: 558 AKILRIQLELTQVKSEIDRKIAEKDEEIEQ-LKRNYQRTVETMQSALDAEVRSRNEAIRL 616
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
++ + ++ + EI ++ + LR Q + + Q L++ L G +E+L
Sbjct: 617 KKKMEGDLNEI--EIQLSHANRQAAETLKHLRSVQGQLKDTQL---HLDDALRG--QEDL 669
Query: 951 NEKESLIIKQTKLFQQKA-ECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
E+ +++ ++ L Q + E L + +++ K EL S ++ ++ + +H
Sbjct: 670 KEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLDS-NERVQLLHTQNTSLIHT 728
Query: 1010 TKAIDKDIRE 1019
K ++ D+ +
Sbjct: 729 KKKLETDLMQ 738
Score = 45.2 bits (102), Expect = 0.001
Identities = 105/495 (21%), Positives = 209/495 (42%), Gaps = 86/495 (17%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
++ +DLQ K + + KS E+ ++ + Q +K VD++ + L ++
Sbjct: 6 QQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 65
Query: 670 MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ 729
S+++ + D LD +++ K FE + Q V+ E TL
Sbjct: 66 ESILD----------LENDKQQLDERLKK-----KDFEYCQLQ-SKVEDEQTLG------ 103
Query: 730 VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-NLEESK 788
+ F++KI L+ R++ ++++ A E+ T+AK T+K+ D LEE
Sbjct: 104 LQFQKKIKELQARIEELEEEIEA---------ERATRAK-----TEKQRSDYARELEELS 149
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
++L+ +T ++ L +K EA E ++ RDL EA + A V
Sbjct: 150 ERLEE------------AGGVTSTQIELNKKREA--EFLKLRRDLEEATLQHEAMVATLR 195
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
K AE+ + +++ +Q KL +++ + + L+ ++++ A
Sbjct: 196 KKHADSVAELGE--------QIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANL 247
Query: 909 EVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKA 968
E R L+D L + + NE++ E +K L + +L +Q
Sbjct: 248 EKICRTLEDQLSEARGK-------------NEEIQRSLSELTTQKSRLQTEAGELSRQLE 294
Query: 969 ECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD---IREYAVALD 1025
E +S+L +S + F + E+ L + +E++ + K H ++ D +RE
Sbjct: 295 EKESIVSQLSRSKQAFTQQTEE-LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQ 353
Query: 1026 KCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQSKN 1085
+ E R + N + + WR Y + D I+ +TE +E ++K R+ S+
Sbjct: 354 EGKAELQR-ALSKANSEVAQ-WRTKY---ETDAIQ-RTE---ELEEAKKKLAQRLQDSEE 404
Query: 1086 GVEIDMRGRCSAGQK 1100
VE + +C++ +K
Sbjct: 405 QVEA-VNAKCASLEK 418
Score = 42.7 bits (96), Expect = 0.008
Identities = 89/455 (19%), Positives = 185/455 (40%), Gaps = 27/455 (5%)
Query: 611 KVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDT-------QIKTLNE 663
K+ DL+ A ++ + K ++ KD E QL+ ++ D T +IK L
Sbjct: 56 KLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQA 115
Query: 664 TVEEITMSL-IEPEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDVDS 718
+EE+ + E + T KQ ++ L ++E VT + E K++ +
Sbjct: 116 RIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEF-L 174
Query: 719 EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKK 777
++ D+ A + + ++TLR + + +L LQ + +K K K E L
Sbjct: 175 KLRRDLEEA-TLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDL 233
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE----KIEAKTEVVRRNRDL 833
+ ++ +SK L+ C ++ +L E K +TE +R L
Sbjct: 234 SSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQL 293
Query: 834 IEAGS--AYIAKVEVAF-NKVKSLDAEI-QQHKKKN-VPREMEKIQEANDKLMEKQKQIM 888
E S + +++ + AF + + L ++ +++K KN + ++ + D L E+ ++
Sbjct: 294 EEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQ 353
Query: 889 TDRQVLTKKIDTLKDEIAK-QEVYKRD-LDDNLCLRKAQTDITNWQKQDDELNEKLNGIN 946
+ L + + E+A+ + Y+ D + L +A+ + + +E E +N
Sbjct: 354 EGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKC 413
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYE 1006
K+ L + L + L K + F L + +K E+ E
Sbjct: 414 ASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTK-CEESQAELEAS 472
Query: 1007 LHVTKAIDKDIREYAVALDKCLMEFHREKMENINM 1041
L ++++ ++ + A ++ L + K EN N+
Sbjct: 473 LKESRSLSTELFKLKNAYEEALDQLETVKRENKNL 507
>X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein.
Length = 2349
Score = 66.9 bits (156), Expect = 4e-10
Identities = 162/978 (16%), Positives = 378/978 (38%), Gaps = 68/978 (6%)
Query: 81 QVKLKIVNAKDKQLEVTRSM--KVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADL 138
Q ++++V++ +Q ++ R + + T +A D L++ + T S A +
Sbjct: 598 QHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTSQTVSTPAPV 657
Query: 139 DILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIR 198
++ E +KA L + + + K E+ +++ ++ +D + KI
Sbjct: 658 PVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKL--QEQVTDLRSQNTKIS 715
Query: 199 KDYAQNLKLLENYATTVKAKQKELEDSYKKN---TSFNKEEEKIANEKSSNEIEYNKFIL 255
K E V+ ++E+ +++N T+ +++E+I N + + N+ +
Sbjct: 716 TQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLA 775
Query: 256 LESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ-K 314
+ E + K+ +++++ +++ + + + +N T L+ ++ + + + K
Sbjct: 776 VAEVRAENL-KKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETK 834
Query: 315 SQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXX 374
+ + +K + + + + +
Sbjct: 835 QRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELL 894
Query: 375 XXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK 434
KQ + + ++ Q K ++++D+L ++ + ++Q LKE+
Sbjct: 895 KNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKER 954
Query: 435 EMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXX 494
+ ++ Q +V T+L E L EK + K EV
Sbjct: 955 -LKTSTSNVEQYQAMV------TSLEESLNK--EKQVTEEVRK-----NIEVRLKESAEF 1000
Query: 495 XXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTV-EKLQD 553
+E E++ +E +++R + E ++ + TLS V E LQ
Sbjct: 1001 QTQLEKKLMEVEKEK-QELQDDKRRAIESMEQQLSEL------KKTLSSVQNEVQEALQR 1053
Query: 554 EQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
L + + Q K +E E K+ V
Sbjct: 1054 ASTALSNEQQARRDCQEQAK---IAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVR 1110
Query: 614 EDLQRASAKKD-EILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS 671
+ L+ + K + ++L K S E+ LKD E+ + R D++ Q + L++ +E+++
Sbjct: 1111 QHLEETTQKAESQLLECKASWEERERMLKD-EVSKCVCRCEDLEKQNRLLHDQIEKLSDK 1169
Query: 672 LIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD 731
++ K ++ + + ++I + + KE +E +VA + +
Sbjct: 1170 VVA-SVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEI-----AETRFEVAQVESLR 1223
Query: 732 FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-----NLEE 786
++Q++ L ++ + LNA +K+Q KT A+ E L + + ++V L E
Sbjct: 1224 YRQRVELLERELQELEDSLNAEREKVQV--TAKTMAQHEELMKKTETMNVVMETNKMLRE 1281
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG-SAYIAKVE 845
K++L+ D I PL+ A E + K+ +++ + L+E + A+ +
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAE-LSEKSGMLQAEKKLLEEDVKRWKARNQ 1340
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK---IDTLK 902
++ K D E + ++IQ+ +++ + +I LT I +LK
Sbjct: 1341 HLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLK 1400
Query: 903 DEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK 962
+++ K K + +L I + Q++ + + + I + + E L +Q K
Sbjct: 1401 EDLNKVRTEKETIQKDL-----DAKIIDIQEKVKTITQ-VKKIGRRYKTQYEELKAQQDK 1454
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEKSL------SKDIEKKFREKMYELHVTKAIDKD 1016
+ + A+ +G E S++ + EL+++L SK +E + L + ++
Sbjct: 1455 VMETSAQSSGDHQEQHVSVQEMQ-ELKETLNQAETKSKSLESQVENLQKTLSEKETEARN 1513
Query: 1017 IREYAVALDKCLMEFHRE 1034
++E V L L ++
Sbjct: 1514 LQEQTVQLQSELSRLRQD 1531
Score = 47.6 bits (108), Expect = 3e-04
Identities = 91/434 (20%), Positives = 192/434 (44%), Gaps = 51/434 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
KLE+ +++QR D+ S+ E+ + ++E ++ D+ QI+ L +EE
Sbjct: 457 KLEQAMKEIQRLQEDTDKANKQSSVLER-------DNRRMEIQVKDLSQQIRVLLMELEE 509
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + ++++++A I ++ +++ + + E +++Q + + + +
Sbjct: 510 ARGNHVIRDEEVSSA-DISSSSEVISQHLVSYRNI----EELQQQ----NQRLLVALREL 560
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ +++ T +++ Q KL + +L+ L K + + +L+++ + +D+ + S
Sbjct: 561 GETREREEQETTSSKITELQLKLESALTELEQL-RKSRQHQMQLVDSIVRQRDMYRILLS 619
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV-VRRNRDLIEAGSAYIAKVEV 846
+ + A TP + + + V V + + IEA +A + +++
Sbjct: 620 QTTGVA-IPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAA-LKQLQE 677
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
F K AE K +N ++EK+QE L + +I T +K+ + L+D +
Sbjct: 678 IFENYKKEKAE--NEKIQN--EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNV- 732
Query: 907 KQEVYKRDL----DDNLCL---RKAQTDITNWQKQD-DELNEKL--NGINKEEL-NEKES 955
E Y+R++ + N L + Q I N QD NEKL + E L EKE
Sbjct: 733 --EGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEM 790
Query: 956 LIIKQTKLFQQK----AECTGA------LSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
L + + +L QQ+ AE G L ++ L+ E ++ LS IEK E
Sbjct: 791 LKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEIS- 849
Query: 1006 ELHVTKAIDKDIRE 1019
H+ K ++ ++ +
Sbjct: 850 --HLKKKLENEVEQ 861
Score = 47.2 bits (107), Expect = 4e-04
Identities = 113/654 (17%), Positives = 260/654 (39%), Gaps = 64/654 (9%)
Query: 386 QAENEL-NIEECQQEINEDEK-AVEQYEQEMDELSQKITK--------LQKQTAKLKEKE 435
Q E +L +E+ +QE+ +D++ A+E EQ++ EL + ++ LQ+ + L ++
Sbjct: 1003 QLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQ 1062
Query: 436 MIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXX 495
+ + + K + +NK++ LM +V A VR +
Sbjct: 1063 QARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAES 1122
Query: 496 XXXXXXXLEAERKHIR-----------ESLNERR----SELTKAEDKIYKAC--GTQ-PY 537
ER+ + E L ++ ++ K DK+ + G Q P
Sbjct: 1123 QLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPL 1182
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
+V+LS E+ + ++ +L+ FI + + + + + E
Sbjct: 1183 NVSLS------EEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQ 1236
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQ 657
+N + +VT + A+ +E+ MK ++ ++ + EK ++ D Q
Sbjct: 1237 ELEDSLNAEREKVQVTA---KTMAQHEEL--MKKTETMNVVMETNKMLREEKERLEQDLQ 1291
Query: 658 IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDV 716
+ V ++ + ++ ++ + G + + ++E +K + + + Q D
Sbjct: 1292 --QMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDP 1349
Query: 717 DSEMTLDVATAKQVDFK------QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
D+E + + K+V K ++I L+ + + L + +Q+L E K + E
Sbjct: 1350 DTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTE 1409
Query: 771 LLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR 829
QK + I++++E K + + ++ ++ + +
Sbjct: 1410 KETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQ 1469
Query: 830 NRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT 889
+ + E + A K KSL+++++ +K +E E + ++ ++ Q ++
Sbjct: 1470 HVSVQEMQELK-ETLNQAETKSKSLESQVENLQKTLSEKETEA-RNLQEQTVQLQSELSR 1527
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
RQ L + T ++E +Q++ +++ + A++ I + L G+ +
Sbjct: 1528 LRQDLQDR--TTQEEQLRQQITEKEEKTRKAIVAAKSKIAH-----------LAGVKDQL 1574
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
E E L + L QQK E ++ LK +G + LE+ L + E+ ++
Sbjct: 1575 TKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQR 1628
Score = 44.4 bits (100), Expect = 0.002
Identities = 80/444 (18%), Positives = 191/444 (43%), Gaps = 21/444 (4%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LEK+ L+ + K E+ + N I + +LE D+ + L++ +E
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEY 140
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+T + +K+ + G++ + +Q K E EQ ++ + T
Sbjct: 141 LTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTE 200
Query: 728 KQVDFKQKISTLRNR-VKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ + ++ R + + + K N NKK + L E+ K + QK V+D++
Sbjct: 201 LKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK 260
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR-----NRDLIEAGSA 839
+ K+ Q+ ++ L + + EAK+ + R ++ L EAG A
Sbjct: 261 LKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEA 320
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL-MEKQKQIMTDRQVLTKKI 898
A ++ +V+ ++++ + + R ++++ AND L K+K + + L
Sbjct: 321 NKA-IQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 899 DTLK--DEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
T +I K + +L + + Q + + ++ +N+ L+ I K E+ K +
Sbjct: 380 PTAAAVAKIVKPGMKLTELYN--AYVETQDQLLLEKLENKRINKYLDEIVK-EVEAKAPI 436
Query: 957 IIKQTKLFQQKAECTGALS-ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+ +Q + +++ + +LS +L++++K E+++ L +D +K ++ + ++
Sbjct: 437 LKRQREEYERAQKAVASLSVKLEQAMK----EIQR-LQEDTDKANKQSSVLERDNRRMEI 491
Query: 1016 DIREYAVALDKCLMEFHREKMENI 1039
+++ + + LME + ++
Sbjct: 492 QVKDLSQQIRVLLMELEEARGNHV 515
Score = 44.0 bits (99), Expect = 0.003
Identities = 71/349 (20%), Positives = 147/349 (42%), Gaps = 33/349 (9%)
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT 759
K ++ E ++EQ D+ S+ T ++T Q+DF K R + Q + + +++ +
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNT-KIST--QLDFASK------RYEMLQDNVEGYRREITS 741
Query: 760 LYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEK 819
L+E+ K L T +K + I+N + D L+ KEK
Sbjct: 742 LHERNQK----LTATTQKQEQIINT------MTQDLRGANEKLAVAEVRAENLK---KEK 788
Query: 820 IEAKTEVVR--RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
K VR + R+ + A + ++ + + K+ + ++EK++
Sbjct: 789 EMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEI 848
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL--CLRKAQTDITNWQKQD 935
L +K + + R LT+ +D + +Q + +L N L+ AQ +I ++
Sbjct: 849 SHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHL 908
Query: 936 DELNEKLNGINKEELNEKESLIIKQTK-LFQQKAECTGALSELKKSLKGFRNELEK--SL 992
+ ++ + + + + + L Q + +++LK+ LK + +E+ ++
Sbjct: 909 SNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAM 968
Query: 993 SKDIEKKF-REKMYELHVTKAID---KDIREYAVALDKCLMEFHREKME 1037
+E+ +EK V K I+ K+ E+ L+K LME +EK E
Sbjct: 969 VTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQE 1017
>AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein.
Length = 720
Score = 66.9 bits (156), Expect = 4e-10
Identities = 107/464 (23%), Positives = 214/464 (46%), Gaps = 58/464 (12%)
Query: 622 KKDEILSMKSLNEKITTLKD-TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMT 680
+KDE + E+ +++ ++ L R+ + +T + + ++++ E+K T
Sbjct: 201 RKDEASKITIWKEQYRVVQEENQVDALRLRLEEKETMLNKKTKQIQDMA------EEKGT 254
Query: 681 TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLR 740
A +IH MLD +++ + KK E ++EQ D + +M+ + ++V Q +T
Sbjct: 255 QAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMS---SLKERVKSLQADTTNT 311
Query: 741 NRVKTT-QKKLNAHNKKLQTLYEKKTK----AKEELLNTQKKVQDI---VNL-------- 784
+ TT ++ L + ++ L E++ + +EE+ N +K ++D+ V+L
Sbjct: 312 DTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEK 371
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
E S L+ + LE+AL++K E ++ + + EA A
Sbjct: 372 EASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASP 431
Query: 845 EVAFNKVKSLDAEIQQHKKKN------VPREMEKIQEANDKLMEKQKQI-----MTDRQV 893
E++ ++++ L+ EI ++K ++ V R +E ++E ++ +K K+I +T RQV
Sbjct: 432 EMS-DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQV 490
Query: 894 --LTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITN--WQKQDDELNEKLNGINKEE 949
KK+ LK K++V K+ L + + D N Q+ D L +K + I + E
Sbjct: 491 KDQNKKVANLKH---KEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELE 547
Query: 950 LNEKESLII---KQTKLFQQKAECTGA---LSELKKSLKGFRNELEKSLSK--DIEKKFR 1001
+ES+ I ++ L Q+++ T A + EL +++ + ELE +K ++
Sbjct: 548 EALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLA 607
Query: 1002 EKMYELHVTK---AIDKDIREYAVALDKCLMEFHREKMENINMI 1042
EK E H+T K + E + L+ EK NI ++
Sbjct: 608 EK--ETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALL 649
Score = 59.3 bits (137), Expect = 8e-08
Identities = 73/403 (18%), Positives = 172/403 (42%), Gaps = 15/403 (3%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+++ + E+ + + ++ M + E+ + +I L++++ D + Q+ +L E V+
Sbjct: 244 QIQDMAEEKGTQAGEIHDLKDMLDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKS 303
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK-----FEAVKEQCGDVDSEMTL 722
+ + +TT ++ + ++E + ++ + K+ D+ +++L
Sbjct: 304 LQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSL 363
Query: 723 ---DVAT--AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
D++ A +D K+ S+L + +L L+ E+ K + +L +
Sbjct: 364 LQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEA 423
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG 837
+ E ++Q A ++ L+ E + E +++ + E
Sbjct: 424 ALEARASPEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELE 483
Query: 838 SAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
S +V+ KV +L + Q KKK+ + +E+ + D L + +Q+ L KK
Sbjct: 484 SLTSRQVKDQNKKVANLKHKEQVEKKKSA-QMLEEARRREDNLNDSSQQLQDS---LRKK 539
Query: 898 IDTLKD-EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
D +++ E A +E + + + L + ++ TN +KQ +EL + + +E + K L
Sbjct: 540 DDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKL 599
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
Q L +++ T +E +K L+ +++L I +K
Sbjct: 600 SSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEK 642
Score = 45.2 bits (102), Expect = 0.001
Identities = 70/383 (18%), Positives = 157/383 (40%), Gaps = 11/383 (2%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
EI++ + ++ E++++ L +KI LQ+Q L++KE +LK + K L TA
Sbjct: 258 EIHDLKDMLDVKERKVNVLQKKIENLQEQ---LRDKEKQMSSLKERVKSLQADTTNTDTA 314
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L L + EK+ TI + + + + L+ + ++ L+E+
Sbjct: 315 LTTLEEALAEKE--RTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKE 372
Query: 519 SELTKAEDKIYK-ACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSC 577
+ L ++ A D L +E+ ++E ++S + ++ L+ +
Sbjct: 373 ASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMESQ--LKKAHEAALEARAS 430
Query: 578 CPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKIT 637
+ +R E E V LE + E + K +I ++SL +
Sbjct: 431 PEMSDRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQV 490
Query: 638 TLKDTEIPQLE-KRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI 696
++ ++ L+ K V+ + L E +Q + ++ + L+ +
Sbjct: 491 KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEAL 550
Query: 697 QEIKTVTKKFEAV--KEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+E +T + E V +E+ ++E ++ KQ++ +++ ++ +TQ+ L
Sbjct: 551 RESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 610
Query: 755 KKLQTLYEKKTKAKEELLNTQKK 777
L L ++ K EE+L +++
Sbjct: 611 THLTNLRAERRKHLEEVLEMKQE 633
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 66.1 bits (154), Expect = 7e-10
Identities = 124/664 (18%), Positives = 269/664 (40%), Gaps = 48/664 (7%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
++ Q+EI ++ + E ++ S + T + + K +++ + L+ E+Q+ LK
Sbjct: 894 LKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQ-LRQTEEQVNDLK 952
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
+ KT+ NV + VT E + E + + +
Sbjct: 953 ERLKTST----SNVEQYQAMVT--SLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEK 1006
Query: 513 SLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-QNVLQSSMFIINKYKGQ 571
L E E + +D +A + + LS+ T+ +Q+E Q LQ + ++ +
Sbjct: 1007 KLMEVEKEKQELQDDKRRAI--ESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQA 1064
Query: 572 LKD----NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD-EI 626
+D +E E K+ V + L+ + K + ++
Sbjct: 1065 RRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQL 1124
Query: 627 LSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQI 685
L K S E+ LKD E+ + R D++ Q + L++ +E+++ ++ K +
Sbjct: 1125 LECKASWEERERMLKD-EVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVA-SVKEGVQGPL 1182
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ + + ++I + + KE +E +VA + + ++Q++ L ++
Sbjct: 1183 NVSLSEEGKSQEQILEILRFIRREKEI-----AETRFEVAQVESLRYRQRVELLERELQE 1237
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-----NLEESKKQLQSDCXXXXX 800
Q LNA +K+Q KT A+ E L + + ++V L E K++L+ D
Sbjct: 1238 LQDSLNAEREKVQV--TAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQA 1295
Query: 801 XXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG-SAYIAKVEVAFNKVKSLDAEIQ 859
I PL+ A E + K+ +++ + L+E + A+ + ++ K D E
Sbjct: 1296 KVRKLELDILPLQEANAE-LSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEY 1354
Query: 860 QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK---IDTLKDEIAKQEVYKRDLD 916
+ ++IQ+ +++ + +I LT I +LK+++ K K +
Sbjct: 1355 RKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTEKETIQ 1414
Query: 917 DNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSE 976
+L I + Q++ + + + I + + E L +Q K+ + A+ +G E
Sbjct: 1415 KDL-----DAKIIDIQEKVKTITQ-VKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQE 1468
Query: 977 LKKSLKGFRNELEKSL------SKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLME 1030
S++ + EL+++L SK +E + L + ++++E V L L
Sbjct: 1469 QHVSVQEMQ-ELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSR 1527
Query: 1031 FHRE 1034
++
Sbjct: 1528 LRQD 1531
Score = 48.0 bits (109), Expect = 2e-04
Identities = 92/434 (21%), Positives = 192/434 (44%), Gaps = 51/434 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
KLE+ +++QR D+ S+ E+ + ++E ++ D+ QI+ L +EE
Sbjct: 457 KLEQAMKEIQRLQEDTDKANKQSSVLER-------DNRRMEIQVKDLSQQIRVLLMELEE 509
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + ++++++A I ++ +++ + + E +++Q + + + +
Sbjct: 510 ARGNHVIRDEEVSSA-DISSSSEVISQHLVSYRNI----EELQQQ----NQRLLVALREL 560
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ +++ T +++ Q KL + +L+ L K + + +L+++ + +D+ + S
Sbjct: 561 GETREREEQETTSSKITELQLKLESALTELEQL-RKSRQHQMQLVDSIVRQRDMYRILLS 619
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV-VRRNRDLIEAGSAYIAKVEV 846
+ + A TP + + + V V + + IEA +A + +++
Sbjct: 620 QTTGVA-IPLHASSLDDVSLASTPKRPSTSQTVSTPAPVPVIESTEAIEAKAA-LKQLQE 677
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
F K AE K +N ++EK+QE L + +I T +K+ + L+D +
Sbjct: 678 IFENYKKEKAE--NEKIQN--EQLEKLQEQVTDLRSQNTKISTQLDFASKRYEMLQDNV- 732
Query: 907 KQEVYKRDL----DDNLCL---RKAQTDITNWQKQD-DELNEKL--NGINKEEL-NEKES 955
E Y+R++ + N L + Q I N QD NEKL I E L EKE
Sbjct: 733 --EGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEM 790
Query: 956 LIIKQTKLFQQK----AECTGA------LSELKKSLKGFRNELEKSLSKDIEKKFREKMY 1005
L + + +L QQ+ AE G L ++ L+ E ++ LS IEK E
Sbjct: 791 LKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEIS- 849
Query: 1006 ELHVTKAIDKDIRE 1019
H+ K ++ ++ +
Sbjct: 850 --HLKKKLENEVEQ 861
Score = 47.2 bits (107), Expect = 4e-04
Identities = 113/654 (17%), Positives = 260/654 (39%), Gaps = 64/654 (9%)
Query: 386 QAENEL-NIEECQQEINEDEK-AVEQYEQEMDELSQKITK--------LQKQTAKLKEKE 435
Q E +L +E+ +QE+ +D++ A+E EQ++ EL + ++ LQ+ + L ++
Sbjct: 1003 QLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQ 1062
Query: 436 MIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXX 495
+ + + K + +NK++ LM +V A VR +
Sbjct: 1063 QARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAES 1122
Query: 496 XXXXXXXLEAERKHIR-----------ESLNERR----SELTKAEDKIYKAC--GTQ-PY 537
ER+ + E L ++ ++ K DK+ + G Q P
Sbjct: 1123 QLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPL 1182
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
+V+LS E+ + ++ +L+ FI + + + + + E
Sbjct: 1183 NVSLS------EEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQ 1236
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQ 657
+N + +VT + A+ +E+ MK ++ ++ + EK ++ D Q
Sbjct: 1237 ELQDSLNAEREKVQVTA---KTMAQHEEL--MKKTETMNVVMETNKMLREEKERLEQDLQ 1291
Query: 658 IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDV 716
+ V ++ + ++ ++ + G + + ++E +K + + + Q D
Sbjct: 1292 --QMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDP 1349
Query: 717 DSEMTLDVATAKQVDFK------QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
D+E + + K+V K ++I L+ + + L + +Q+L E K + E
Sbjct: 1350 DTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKVRTE 1409
Query: 771 LLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR 829
QK + I++++E K + + ++ ++ + +
Sbjct: 1410 KETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQ 1469
Query: 830 NRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT 889
+ + E + A K KSL+++++ +K +E E + ++ ++ Q ++
Sbjct: 1470 HVSVQEMQELK-ETLNQAETKSKSLESQVENLQKTLSEKETEA-RNLQEQTVQLQSELSR 1527
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
RQ L + T ++E +Q++ +++ + A++ I + L G+ +
Sbjct: 1528 LRQDLQDR--TTQEEQLRQQITEKEEKTRKAIVAAKSKIAH-----------LAGVKDQL 1574
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
E E L + L QQK E ++ LK +G + LE+ L + E+ ++
Sbjct: 1575 TKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREHQERHLEQR 1628
Score = 45.2 bits (102), Expect = 0.001
Identities = 61/416 (14%), Positives = 171/416 (41%), Gaps = 12/416 (2%)
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+E ++ + ++ + E+I ++ +++ + + + L + E +
Sbjct: 732 VEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEML 791
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEA-VKEQCGDVDSEMTLDVATA 727
+S + Q+ + +L +Q I+ + ++ E K++ ++ +++
Sbjct: 792 KLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHL 851
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV-NLEE 786
K+ + ++ + +L ++L T KE L N QK++ + +L
Sbjct: 852 KK-KLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSN 910
Query: 787 SKKQLQSDCXXXXXXXXXXXXA-ITPLEVALK---EKIEAKTEVVRRNRDLIEAGSAYIA 842
+ Q+ S + L L+ E++ E ++ + +E A +
Sbjct: 911 MEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVT 970
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLK 902
+E + NK K + E++++ + + E + KLME +K+ + + I++++
Sbjct: 971 SLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESME 1030
Query: 903 DEIAKQEVYKRDLDDNL--CLRKAQTDITNWQKQDDELNEKLN-GINKEELNEKESLI-I 958
++++ + + + + L++A T ++N Q+ + E+ + + E+E ++
Sbjct: 1031 QQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHA 1090
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK-DIEKKFREKMYELHVTKAI 1013
+ Q E ++ +++ L+ + E L + + RE+M + V+K +
Sbjct: 1091 ADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCV 1146
Score = 44.4 bits (100), Expect = 0.002
Identities = 80/444 (18%), Positives = 191/444 (43%), Gaps = 21/444 (4%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LEK+ L+ + K E+ + N I + +LE D+ + L++ +E
Sbjct: 81 ELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEY 140
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+T + +K+ + G++ + +Q K E EQ ++ + T
Sbjct: 141 LTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTE 200
Query: 728 KQVDFKQKISTLRNR-VKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ + ++ R + + + K N NKK + L E+ K + QK V+D++
Sbjct: 201 LKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTK 260
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR-----NRDLIEAGSA 839
+ K+ Q+ ++ L + + EAK+ + R ++ L EAG A
Sbjct: 261 LKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEA 320
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL-MEKQKQIMTDRQVLTKKI 898
A ++ +V+ ++++ + + R ++++ AND L K+K + + L
Sbjct: 321 NKA-IQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 899 DTLK--DEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
T +I K + +L + + Q + + ++ +N+ L+ I K E+ K +
Sbjct: 380 PTAAAVAKIVKPGMKLTELYN--AYVETQDQLLLEKLENKRINKYLDEIVK-EVEAKAPI 436
Query: 957 IIKQTKLFQQKAECTGALS-ELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+ +Q + +++ + +LS +L++++K E+++ L +D +K ++ + ++
Sbjct: 437 LKRQREEYERAQKAVASLSVKLEQAMK----EIQR-LQEDTDKANKQSSVLERDNRRMEI 491
Query: 1016 DIREYAVALDKCLMEFHREKMENI 1039
+++ + + LME + ++
Sbjct: 492 QVKDLSQQIRVLLMELEEARGNHV 515
Score = 44.4 bits (100), Expect = 0.002
Identities = 71/349 (20%), Positives = 147/349 (42%), Gaps = 33/349 (9%)
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT 759
K ++ E ++EQ D+ S+ T ++T Q+DF K R + Q + + +++ +
Sbjct: 691 KIQNEQLEKLQEQVTDLRSQNT-KIST--QLDFASK------RYEMLQDNVEGYRREITS 741
Query: 760 LYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEK 819
L+E+ K L T +K + I+N + D L+ KEK
Sbjct: 742 LHERNQK----LTATTQKQEQIINT------MTQDLRGANEKLAVAEIRAENLK---KEK 788
Query: 820 IEAKTEVVR--RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
K VR + R+ + A + ++ + + K+ + ++EK++
Sbjct: 789 EMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEI 848
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL--CLRKAQTDITNWQKQD 935
L +K + + R LT+ +D + +Q + +L N L+ AQ +I ++
Sbjct: 849 SHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHL 908
Query: 936 DELNEKLNGINKEELNEKESLIIKQTK-LFQQKAECTGALSELKKSLKGFRNELEK--SL 992
+ ++ + + + + + L Q + +++LK+ LK + +E+ ++
Sbjct: 909 SNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAM 968
Query: 993 SKDIEKKF-REKMYELHVTKAID---KDIREYAVALDKCLMEFHREKME 1037
+E+ +EK V K I+ K+ E+ L+K LME +EK E
Sbjct: 969 VTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQE 1017
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 66.1 bits (154), Expect = 7e-10
Identities = 130/724 (17%), Positives = 289/724 (39%), Gaps = 65/724 (8%)
Query: 386 QAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK------EM--I 437
+ E E+N E ++ N ++K ++++D+L +TK++K+ + K EM +
Sbjct: 931 EEEEEMNSELVAKKRNLEDKC-SSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTAL 989
Query: 438 EENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTIN-KFE---CEVRNEVXXXXXXX 493
EEN+ K+ L+ H+ L +L + + + IN K E ++ +
Sbjct: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLR 1049
Query: 494 XXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQD 553
LE + K +ES+ + +E + E+K+ K + LS+ ++ Q
Sbjct: 1050 ADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKK------EFELSQLQARIDDEQV 1103
Query: 554 EQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT 613
Q + + +L++ E E+E ++ +LE+++
Sbjct: 1104 HSLQFQKKIKELQARIEELEE-----------EIEAEHTLRAKIEKQRS-DLARELEEIS 1151
Query: 614 EDLQRASAKKDEILSMKSLNEK--ITTLKDTEIPQLEKRIVDVDTQIKTLNETVE--EIT 669
E L+ AS + M E +D E L+ + K + E E
Sbjct: 1152 ERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQI 1211
Query: 670 MSLIEPEQKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-LDVATA 727
+L +QK+ K ++ M +D I+ ++K ++ C V+ + + +
Sbjct: 1212 DNLQRVKQKLEKEK---SELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDE 1268
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+Q ++ + R++T +L+ ++ ++L + TK+K+ L TQ+ LEE
Sbjct: 1269 QQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQAL--TQQ-------LEEL 1319
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
K+Q++ + + ++ L+E+ E + E + + ++ +A+ +
Sbjct: 1320 KRQMEEETKAKNAMAHALQSSRHDCDL-LREQYEEEQEAKAELQRALSKANSEVAQWKTK 1378
Query: 848 FNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAK 907
+ E + KK + + +++ +E + K + +Q L +++ L ++ +
Sbjct: 1379 YETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLER 1438
Query: 908 QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQK 967
LD R + W+++ DE +L K E SL + K+
Sbjct: 1439 SHTACATLDKK--QRNFDKVLAEWKQKLDESQAELEAAQK----ESRSLSTELFKMRNAY 1492
Query: 968 AECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKC 1027
E L L++ K + E+ L++ I + + K ++++ + VAL++
Sbjct: 1493 EEVVDQLETLRRENKNLQEEI-SDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEV 1551
Query: 1028 LMEFHREKME------NINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVV 1081
E+ + ++ + EL RK+ D + ++K E+ + D +
Sbjct: 1552 EGSLEHEESKILRVQLELSQVKSELDRKVIE-KDEEIEQLKRNSQRAAEALQSVLDAE-I 1609
Query: 1082 QSKN 1085
+S+N
Sbjct: 1610 RSRN 1613
Score = 58.4 bits (135), Expect = 1e-07
Identities = 136/701 (19%), Positives = 276/701 (39%), Gaps = 67/701 (9%)
Query: 392 NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEM-IEENLKTKEKQLIV 450
+ E ++E+ E ++ E++M L Q+ LQ Q E M EE + K I+
Sbjct: 859 DFERTKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKIL 918
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
L+ K K L E L E + + K E ++ +E E+
Sbjct: 919 LEAKVKE-LTERLEEEEEMNSELVAKKRNLE--DKCSSLKRDIDDLELTLTKVEKEKHAT 975
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKG 570
+ E+T E+ I K T+ + T++ LQ E++ + + I K +
Sbjct: 976 ENKVKNLSEEMTALEENISKL--TKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQ 1033
Query: 571 QLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMK 630
Q D E E + + G L+ E + +K +I
Sbjct: 1034 QTDD------LEGSLEQEKKLRADLERAKR---KLEGDLKMSQESIMDLENEKQQI---- 1080
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM----TTAKQIH 686
EK+ K+ E+ QL+ RI D + ++E+ + E E+++ T +I
Sbjct: 1081 --EEKLKK-KEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIE 1137
Query: 687 GDMPMLDRYIQEIK--------TVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
L R ++EI + + E K++ + +M D+ A + + +T
Sbjct: 1138 KQRSDLARELEEISERLEEASGATSAQIEMNKKREAEF-QKMRRDLEEA-TLQHEATAAT 1195
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEESKKQLQSDCXX 797
LR + + +L LQ + +K K K EL + +I L +SK ++ C
Sbjct: 1196 LRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRT 1255
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
+K K E +T+++ DL + + ++V+ ++
Sbjct: 1256 VEDQFS-----------EIKAKDEQQTQLI---HDLNMQKARLQTQNGELSHRVEEKESL 1301
Query: 858 IQQ--HKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
I Q K+ + +++E+++ ++ + + + Q D L+++ +++ K +L
Sbjct: 1302 ISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAEL 1361
Query: 916 DDNLCLRKAQTDITNWQ-KQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA- 973
L KA +++ W+ K + + ++ EEL E + + ++ + ++K E +
Sbjct: 1362 --QRALSKANSEVAQWKTKYETDAIQR-----TEELEEAKKKLAQRLQEAEEKTETANSK 1414
Query: 974 LSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHR 1033
+ L+K+ + + E+E L +D+E+ + DK + E+ LD+ E
Sbjct: 1415 CASLEKTKQRLQGEVE-DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEA 1473
Query: 1034 EKMENINMIIRELW--RKIYRGNDIDYIEIKTEGNLTVESE 1072
+ E+ + EL+ R Y +D +E N ++ E
Sbjct: 1474 AQKES-RSLSTELFKMRNAYE-EVVDQLETLRRENKNLQEE 1512
Score = 53.6 bits (123), Expect = 4e-06
Identities = 160/894 (17%), Positives = 339/894 (37%), Gaps = 70/894 (7%)
Query: 101 KVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCH 160
KV L K K + T D G + ADL+ + G K S++
Sbjct: 1020 KVNGLIKINAKLEQ-----QTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLE 1074
Query: 161 QEDSSWPLDEGKKVKERFDEIFDA---DKYSDCLDRLKKIRKDYAQNLKLLENYAT--TV 215
E ++E K KE A D+ L KKI++ A+ +L E T+
Sbjct: 1075 NEKQQ--IEEKLKKKEFELSQLQARIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTL 1132
Query: 216 KAK-QKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQ----EKIDKRNEQ 270
+AK +K+ D ++ ++ E+ A+ +S +IE NK E Q E+ ++E
Sbjct: 1133 RAKIEKQRSDLARELEEISERLEE-ASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEA 1191
Query: 271 IVETAKIAEIENITEVQTNEEAENATKTILEKVES-LKSDHKVQKSQADEEEKKAQGFVD 329
T + + +++ E+ + K LEK +S LK + S + K
Sbjct: 1192 TAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIER 1251
Query: 330 ECRSGHTQXXXXXXXXXXXXXXXXXXXXXD--ITSANQSXXXXXXXXXXXXXXXXXHKQA 387
CR+ Q + + N KQA
Sbjct: 1252 TCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQA 1311
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE-KEMIEENLKTKEK 446
+ +EE ++++ E+ KA + L++Q + +E K ++ L
Sbjct: 1312 LTQ-QLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANS 1370
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAE 506
++ K K++T ++ + E + E E + E L+ E
Sbjct: 1371 EVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQR--LQGE 1428
Query: 507 RKHIRESLNERRSE---LTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMF 563
+ + L + L K + K + L + +E Q E L + +F
Sbjct: 1429 VEDLMRDLERSHTACATLDKKQRNFDKVLAE--WKQKLDESQAELEAAQKESRSLSTELF 1486
Query: 564 II-NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTE----DLQR 618
+ N Y+ + N+ + E + K +K+ E DLQ
Sbjct: 1487 KMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQV 1546
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTL---NETVEEITMSLIE 674
A + + L + L+ +++ +L++++++ D +I+ L ++ E S+++
Sbjct: 1547 ALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLD 1606
Query: 675 PEQK-----MTTAKQIHGDMPMLDRYI----QEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
E + + K++ GD+ ++ + +++ + V+ Q D S++ LD A
Sbjct: 1607 AEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQRHLRTVQGQLKD--SQLHLDDA 1664
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI---- 781
D K++++ + R ++L L+ + +++ELL+ +VQ +
Sbjct: 1665 LRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHSQN 1724
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI---EAKTEVVRRNRDLIEAGS 838
+L +KK+L++D E K+ I E +++ +D S
Sbjct: 1725 TSLINTKKKLEADIAQCQAEVENSIQESRNAEEKAKKAITDAAMMAEELKKEQDT----S 1780
Query: 839 AYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
A++ +++ + VK L + + ++ + ++IQ+ +++ E + ++ +++ +
Sbjct: 1781 AHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENELDVEQKRGAEA 1840
Query: 898 IDTLK--DEIAKQEVYKRDLDDNLCLR------KAQTDITNWQKQDDELNEKLN 943
+ + K+ Y+ + D LR K Q + ++++Q +E E+ N
Sbjct: 1841 LKGAHKYERKVKEMTYQAEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQAN 1894
Score = 48.4 bits (110), Expect = 2e-04
Identities = 158/884 (17%), Positives = 327/884 (36%), Gaps = 54/884 (6%)
Query: 161 QEDSSWPLDEGKKVKERFDEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQ 219
+E+ S E K ++E + D D ++ L KI Q LE K +
Sbjct: 990 EENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLR 1049
Query: 220 KELEDSYKK-NTSFNKEEEKIA---NEKSSNEIEYNKFILLESQNQEKIDKRNEQIVE-T 274
+LE + +K +E I NEK E + K SQ Q +ID ++
Sbjct: 1050 ADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARIDDEQVHSLQFQ 1109
Query: 275 AKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVD-ECRS 333
KI E++ ++ EE A T+ K+E +SD + + E ++A G +
Sbjct: 1110 KKIKELQ--ARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEM 1167
Query: 334 GHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNI 393
+ T + ++ E E +
Sbjct: 1168 NKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKS- 1226
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN 453
E + EI++ +E + + + ++ Q +++K K+ + L L + K
Sbjct: 1227 -ELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQL---IHDLNMQKA 1282
Query: 454 KHKTALMELLGNVPEKDFAVT-INKFE---CEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+ +T EL V EK+ ++ + K + + E+ +H
Sbjct: 1283 RLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHALQSSRH 1342
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVT--LSKYTT----TVEKLQDEQNVLQSSMF 563
+ L E+ E +A+ ++ +A +V +KY T E+L++ + L +
Sbjct: 1343 DCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQ 1402
Query: 564 IINKYKGQLKDNSCCPL--CNRGFENESEXXXXXXXXXXXX-MNVPGKLEKVTEDLQRAS 620
+ K + ++ C L + + E E + K + L
Sbjct: 1403 EAEE-KTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWK 1461
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIE-PEQKM 679
K DE + +K + TE+ ++ +V Q++TL + + + + EQ
Sbjct: 1462 QKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIA 1521
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T K + QE + E V+ +S++ QV + +
Sbjct: 1522 ETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVI 1581
Query: 740 RNRVKTTQKKLNAHN--KKLQTLYEKKTKAKEELLNTQKKVQDIVN-----LEESKKQLQ 792
+ Q K N+ + LQ++ + + +++ + L +KK++ +N L S +Q+
Sbjct: 1582 EKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMA 1641
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTE---VVRRNRDLIEAGSAYIAKVEVAFN 849
+ L+ AL+ + K + V RRN L+E + +++VA
Sbjct: 1642 ETQRHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEE----LEEMKVALE 1697
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD-RQVLTKKIDTLKDEIAKQ 908
+ + + + + + ++ + N L+ +K++ D Q + +++++ +
Sbjct: 1698 QTER-TRRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAE 1756
Query: 909 EVYKRDLDDNLC----LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLF 964
E K+ + D L+K Q + ++ L + + + + L+E E L +K K
Sbjct: 1757 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDL-QHRLDEAEQLALKGGKKQ 1815
Query: 965 QQKAECTGALSELKKSLKGFRNELEKSL--SKDIEKKFREKMYE 1006
QK E + EL+ L + ++L + E+K +E Y+
Sbjct: 1816 IQKLE--NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQ 1857
Score = 37.9 bits (84), Expect = 0.22
Identities = 32/134 (23%), Positives = 69/134 (51%), Gaps = 5/134 (3%)
Query: 202 AQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQ 261
A+ LK ++ + ++ +K LE + K E E++A + +I+ + + E +N+
Sbjct: 1770 AEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLENRVRELENE 1829
Query: 262 EKID-KRNEQIVETAKIAE--IENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQAD 318
++ KR + ++ A E ++ +T Q E+ +N + + + V+ L++ K K QA+
Sbjct: 1830 LDVEQKRGAEALKGAHKYERKVKEMT-YQAEEDRKNILR-LQDLVDKLQAKVKSYKRQAE 1887
Query: 319 EEEKKAQGFVDECR 332
E E++A + CR
Sbjct: 1888 EAEEQANTQLSRCR 1901
>BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein.
Length = 634
Score = 64.9 bits (151), Expect = 2e-09
Identities = 86/420 (20%), Positives = 181/420 (43%), Gaps = 28/420 (6%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIEENLKT 443
++ + EL + ++ +D K VEQ +E L QK+ L+ + A+LK EKE E ++
Sbjct: 180 EEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVEN 239
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
++ + + + + L ++ + + E E+++ +
Sbjct: 240 AQRIQVRQLAEMQATVRSL--EAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREI 297
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMF 563
++E + + E+T + K+ A + +K + ++ LQ + +L+++
Sbjct: 298 NTLSSKVKELKHSNKLEIT--DIKLETARAKSELERERNKIQSELDGLQSDNEILKAA-- 353
Query: 564 IINKYKGQL--KDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLE--KVTEDLQRA 619
+ +K L KD E + N LE KV D+ R
Sbjct: 354 -VEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQ 412
Query: 620 SAKK--DEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
S K +E L + E+IT + + +L+++IV ++ K NE ++ + +
Sbjct: 413 SEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNEN-SDLKQQISSLQ 471
Query: 677 QKMTTAKQIHGDM----PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDF 732
++T+ Q D+ ML ++ +K + F + E+ +++E TL+ KQ+ +
Sbjct: 472 IQVTSLAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEK-AQLEAEKTLE---EKQIQW 527
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQ--TLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
++ L + ++K N +KLQ + +KK K+ E N K++Q+ V + E+KK+
Sbjct: 528 LEEKHKLHECITDREEKYNQAKEKLQRAAIAQKKRKSLHE--NKLKRLQEKVEVLEAKKE 585
Score = 34.3 bits (75), Expect = 2.7
Identities = 43/206 (20%), Positives = 92/206 (44%), Gaps = 17/206 (8%)
Query: 710 KEQCGDVDSEMTLDVATAKQVDFKQKISTLRN--RVKTTQKKLNAHNKKLQTLYEKKTKA 767
K + + E+T + ++ +Q+I T+ N + K L LQ ++
Sbjct: 421 KLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSLAQS 480
Query: 768 KEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVV 827
+ +LLN+ + ++++V ++L+ +C A E L+EK + + +
Sbjct: 481 ENDLLNSNQMLKEMV------ERLKQECRNFRSQAEK---AQLEAEKTLEEK---QIQWL 528
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNV-PREMEKIQEANDKLMEKQKQ 886
L E + K A K++ A I Q K+K++ +++++QE + L K+++
Sbjct: 529 EEKHKLHECITDREEKYNQAKEKLQR--AAIAQKKRKSLHENKLKRLQEKVEVLEAKKEE 586
Query: 887 IMTDRQVLTKKIDTLKDEIAKQEVYK 912
+ T+ QVL ++ +D Q+ K
Sbjct: 587 LETENQVLNRQNVPFEDYTRLQKRLK 612
Score = 32.7 bits (71), Expect = 8.2
Identities = 70/397 (17%), Positives = 165/397 (41%), Gaps = 41/397 (10%)
Query: 640 KDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM--PMLDRY-- 695
K T+ +L+ + ++ ++ + +EE+ + ++ P++ QI ++ PM +R+
Sbjct: 69 KQTQQEKLQLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELETPMRERFRN 128
Query: 696 ----IQEIKTVTKK-----------FEAVKEQCGDV--DSEMTLDVATAKQVDFKQKIST 738
+++ + V K FE KE+ + + ++ + A+ + K++
Sbjct: 129 LDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEE--- 185
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXX 797
LRN++ L +K+++ L +K ++L + +V ++ E S+ Q+++
Sbjct: 186 LRNQLLNVD--LTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENAQRI 243
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA----KVEVAFNKVKS 853
+ LE A K+ + E + + + ++ K E N + S
Sbjct: 244 QVRQLAEMQATVRSLE-AEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSS 302
Query: 854 LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
E++ K + + A +L ++ +I ++ L + LK + +V
Sbjct: 303 KVKELKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLV 362
Query: 914 DLDDNLCLRKAQTDITNWQK----QDD--ELNEKLNGINKEELNEKESLIIKQTKLFQQK 967
+ D L + +QK QD+ EL +L + K ++ E + + +++K
Sbjct: 363 EKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKV-EHDVWRQSEKDQYEEK 421
Query: 968 AECTGALSEL-KKSLKGFRNELEKSLSKDIEKKFREK 1003
+ E+ +K L+ R +L++ + IE +EK
Sbjct: 422 LRASQMAEEITRKELQSVRLKLQQQI-VTIENAEKEK 457
>D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein.
Length = 1388
Score = 64.5 bits (150), Expect = 2e-09
Identities = 127/652 (19%), Positives = 274/652 (42%), Gaps = 66/652 (10%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTK 444
K E+ L E ++ + + + A +Y+++ D + K L+ LK+ ++ + + +
Sbjct: 492 KSVESALRQLEREKALLQHKNA--EYQRKADHEADKKRNLENDVNSLKD-QLEDLKKRNQ 548
Query: 445 EKQLIVLK-NKHKTALMELLGNV-PEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
Q+ K N+ + L E + E D A + K + E ++
Sbjct: 549 NSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCL 608
Query: 503 LE-AERKHIRESLN-------ERRSELTKAE---DKIYKACGTQPYDVTLSKYTTTVEKL 551
LE A+ K +E +N ERR +E D + CG + L + K+
Sbjct: 609 LETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEE---DLKNGKILLAKV 665
Query: 552 QDEQNVLQSSMFIINKYKGQLKDNSCCPL--CNRGFENESEXXXXXXXXXXXXMNVPGKL 609
+ E+ LQ + K K ++ + L + E E + +
Sbjct: 666 ELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESI 725
Query: 610 EKVTEDLQRASAKK---DEILSMKSLN-----EKITTLKDTEIPQLEKRIVDVDTQIKTL 661
E+ + + KK + L K N EK +L D ++ Q +++I ++ Q L
Sbjct: 726 EEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVL 785
Query: 662 NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT 721
NE V +T+ + + QK + D+ M + + +K K+ + +E ++ +M
Sbjct: 786 NEDVRNLTLKIEQETQKRCLTQN---DLKMQTQQVNTLKMSEKQLK--QENNHLMEMKMN 840
Query: 722 LDVATAK----QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK---KTKAKEELLNT 774
L+ A+ + D ++ L+++++ Q + +++ L E+ KTK +EL
Sbjct: 841 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK 900
Query: 775 QKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI----EAKTEVVRRN 830
++++QD + QL+ A KEKI E K + R
Sbjct: 901 KQELQD--ERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHK 958
Query: 831 RDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ------ 884
++L E A IA +E N+ + D ++K+ + +++ +QE +L +++
Sbjct: 959 QELTEK-DATIASLEET-NRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI 1016
Query: 885 -----KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQ--KQDDE 937
KQ++T+R + T+ ++ L + + ++E KR D ++ ++ + + + + ++
Sbjct: 1017 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK 1076
Query: 938 LNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
L +++ K ELNE ++ I +++++ + E L ++ R++L+
Sbjct: 1077 LTQQMIKYQK-ELNEMQAQIAEESQI---RIELQMTLDSKDSDIEQLRSQLQ 1124
Score = 43.2 bits (97), Expect = 0.006
Identities = 139/715 (19%), Positives = 293/715 (40%), Gaps = 84/715 (11%)
Query: 386 QAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI----TKLQKQTAKLKEKEMIEENL 441
Q+ +E Q+++ E+ + Q +EL QK T+L+K +L+E+ + +++
Sbjct: 435 QSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSV 494
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
++ +QL + K L K K E
Sbjct: 495 ESALRQL----EREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNS 550
Query: 502 XLEAER-KHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQS 560
+ E+ ++ L+E + L D + TQ ++ + +++L+ LQ
Sbjct: 551 QISTEKVNQLQRQLDETNALLRTESDTAARLRKTQ------AESSKQIQQLESNNRDLQD 604
Query: 561 SMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS 620
++ K +L+ N ESE ++ G++ + EDL+
Sbjct: 605 KNCLLETAKLKLEKE----FINLQSALESERRDRTHGSEIIN-DLQGRICGLEEDLKNGK 659
Query: 621 AKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ L + L E+ T L + E +E +D+ Q+K + +++E+ E E K
Sbjct: 660 ILLAKVELEKRQLQERFTDL-EKEKSNME---IDMTYQLKVIQQSLEQE-----EAEHKA 710
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV-DFKQKIST 738
T A+ D + I+E K+ EA+KE + E TL + + +++ S
Sbjct: 711 TKARL--ADKNKIYESIEEAKS-----EAMKEMEKKLLEERTLKQKVENLLLEAEKRCSL 763
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQL-QSDCXX 797
L +K +Q+K+N L ++K E++ N K++ E K+ L Q+D
Sbjct: 764 LDCDLKQSQQKINE-------LLKQKDVLNEDVRNLTLKIEQ----ETQKRCLTQNDLKM 812
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD-- 855
+ L+ +E K + ++N +L + + + A ++K L
Sbjct: 813 QTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRK-------ERQDADGQMKELQDQ 865
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
E +Q+ ++ +++E ++ + K++ +Q L + D+L ++ + + K D
Sbjct: 866 LEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQL-EITLTKAD- 923
Query: 916 DDNLCLRKAQTDITNWQKQD--DELNEK-LNGINKEELNEKESLIIKQTKLFQQKAECTG 972
+ L A+ ++ +K+ EL K + +K+EL EK++ I L + T
Sbjct: 924 SEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATI---ASLEETNRTLTS 980
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
++ L + N+L KD++++ ++ + ++ A K +K L+
Sbjct: 981 DVANLANEKEELNNKL-----KDVQEQL-SRLKDEEISAAAIK------AQFEKQLLTER 1028
Query: 1033 REKMENINMIIRELWRK--IYRGNDIDYIEIKTEG---NLTVESERRKYDYRVVQ 1082
K + +N + + RK + RGND D + E ++ ++SER K ++++
Sbjct: 1029 TLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIK 1083
Score = 36.3 bits (80), Expect = 0.66
Identities = 61/334 (18%), Positives = 135/334 (40%), Gaps = 26/334 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL-KEKEMIEENLKTKEK 446
+N+L ++ Q++N + + +Q +QE + L + L+KQ A+L KE++ + +K +
Sbjct: 807 QNDLKMQT--QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQD 864
Query: 447 QLIV---LKNKHKTALMELLGNVPEK-DFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
QL +KT + EL EK + + + E+++E
Sbjct: 865 QLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADS 924
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
+ R E ++ E E +I + ++T + T+ L++ L S +
Sbjct: 925 EQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELT--EKDATIASLEETNRTLTSDV 982
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEK--VTEDLQRAS 620
+ K +L N ++ E + + EK +TE +
Sbjct: 983 ANLANEKEEL---------NNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQ 1033
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT----LNETVEEITMSLIEPE 676
A +++ + + E + DT++ + EK + ++K+ L + + + L E +
Sbjct: 1034 A-VNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQ 1092
Query: 677 QKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAV 709
++ QI ++ M LD +I+ + + +A+
Sbjct: 1093 AQIAEESQIRIELQMTLDSKDSDIEQLRSQLQAL 1126
>BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 64.5 bits (150), Expect = 2e-09
Identities = 87/408 (21%), Positives = 178/408 (43%), Gaps = 40/408 (9%)
Query: 611 KVTEDLQRASAKKDEILSMKSLNEKITTLKDTE-----IPQLEKRIVDVDTQIKTLNETV 665
+++ ++ D+ ++KS +K+ TL + + Q+EK I + D ++KT+ E +
Sbjct: 692 EISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELL 751
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKT-----------VTKKFEAVKEQCG 714
E LI+ K I + L + +Q++K V + + + E+ G
Sbjct: 752 ET---GLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDG 808
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLR--NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
+ S L A +V K+K L ++V+ Q L +++ T+ + +++L
Sbjct: 809 KIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 868
Query: 773 NTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
NT K +QD+ ES K + LE+ LKEK + E+ R
Sbjct: 869 NTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEK---ENELKRLEAM 925
Query: 833 LIEAGSAYIAKVEV---AFNKVKSLDAEIQQHKKKNVPR--EMEKIQEANDKLMEKQKQI 887
L E S +K ++ ++ K ++I+Q K++N + +E + E++K+I
Sbjct: 926 LKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEI 985
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK 947
L ++D+LKD + Q DL + +A + + +K L +K+N +K
Sbjct: 986 ----SGLWNELDSLKDAVEHQRKKNNDLREKNW--EAMEALASTEKM---LQDKVNKTSK 1036
Query: 948 EELNEKESLIIKQTKLFQQKAECTGALSELK--KSLKGFRNELEKSLS 993
E + E++ ++ ++ ++ S L + L GF + ++ ++
Sbjct: 1037 ERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMA 1084
Score = 46.8 bits (106), Expect = 5e-04
Identities = 130/703 (18%), Positives = 284/703 (40%), Gaps = 65/703 (9%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKL--QKQTAKLKEKEMIEEN--LKT 443
ENE ++ ++ + + +Q EQ + +L + K ++++ +++ ++++E+N LK
Sbjct: 526 ENE--VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 444 KEKQL---IVLKNKHKTALMELLGNVPEKDFAV--TINKFECEVRNEVXXXXXXXXXXXX 498
+ +Q I + EL + EKD + T + E R+ +
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE-RDRLTSKEEELKDIQN 642
Query: 499 XXXXLEAERKHIRESLNERRS---ELTKAEDKIYKACGT-----QPYDVTLSKYTTTVEK 550
L+AE + ++ NE+ + EL K + +Y + +S +
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702
Query: 551 LQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXM-NVPGKL 609
L D+ L+S + + + + + + + E + V K
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKE 762
Query: 610 EKVTEDLQRASAKKDEILSMKSL-NEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
E++ S+ E+ +K+ N++++ E +L+K I + D +IK++ E +E
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE--ELKKVIHEKDGKIKSVEELLEAE 820
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA-TA 727
+ + E+ + + + +QE++ + K E V E D+A T
Sbjct: 821 LLKVANKEKTVQLS---------ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 871
Query: 728 KQV-DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
K + D +++ +L+ V+ + N + +E+ +E N K+++ + L+E
Sbjct: 872 KWLQDLQEENESLKAHVQEVAQH-NLKEASSASQFEELEIVLKEKENELKRLEAM--LKE 928
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ L S + +E LK++ + + +L++ S ++
Sbjct: 929 RESDLSSKTQLLQDVQDENKLFKSQIE-QLKQQNYQQASSFPPHEELLKVISEREKEISG 987
Query: 847 AFNKVKSL-DAEIQQHKKKNVPRE-----MEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+N++ SL DA Q KK N RE ME + L +K + +RQ + ++
Sbjct: 988 LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVEL 1047
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--------EELNE 952
E+ K+ K + NL + + ++K+ E +G + +E +E
Sbjct: 1048 EAKEVLKKLFPKVSVPSNLSYGEW---LHGFEKKAKECMAGTSGSEEVKVLEHKLKEADE 1104
Query: 953 KESLIIKQTKLFQQK-AECTGALSELKKSLKGFRNELEKSLS------KDIEKKFREKMY 1005
+L+ + + ++ AE G L +L++S++ N+ + + K ++ F
Sbjct: 1105 MHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQ 1164
Query: 1006 ELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMI--IREL 1046
EL ++ +KDI + ME + +ME + +REL
Sbjct: 1165 ELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVREL 1207
Score = 35.1 bits (77), Expect = 1.5
Identities = 77/392 (19%), Positives = 159/392 (40%), Gaps = 50/392 (12%)
Query: 608 KLEKVTEDLQR--ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETV 665
K ++V E ++ A K++ + +++ L+ + +L K D + L E
Sbjct: 407 KFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKT 466
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
++ ++ + A Q+ + +R +E+++ +K A E ++ L
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEA-----AQQDLQ-- 519
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLE 785
+K V + ++ +L +++ T ++L L E + K + + Q +VQDI+
Sbjct: 520 -SKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN 578
Query: 786 ES-KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
E+ K Q+Q + + L L + I K + +++ D
Sbjct: 579 EALKAQIQQ-----FHSQIAAQTSASVLAEELHKVIAEKDKQIKQTED------------ 621
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
SL +E + K E++ IQ N L + +++ Q L + E
Sbjct: 622 --------SLASERDRLTSKE--EELKDIQNMNFLLKAEVQKL----QALANEQAAAAHE 667
Query: 905 IAK--QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK 962
+ K Q VY +D L + Q +I+N ++ LN++ N K E+ + ++L+ +Q
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQ-NKALKSEVQKLQTLVSEQPN 726
Query: 963 --LFQQKAECTGALSELKKSLKGFRNELEKSL 992
+ +Q +C + E + LK LE L
Sbjct: 727 KDVVEQMEKC---IQEKDEKLKTVEELLETGL 755
>BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 64.5 bits (150), Expect = 2e-09
Identities = 87/408 (21%), Positives = 178/408 (43%), Gaps = 40/408 (9%)
Query: 611 KVTEDLQRASAKKDEILSMKSLNEKITTLKDTE-----IPQLEKRIVDVDTQIKTLNETV 665
+++ ++ D+ ++KS +K+ TL + + Q+EK I + D ++KT+ E +
Sbjct: 692 EISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELL 751
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKT-----------VTKKFEAVKEQCG 714
E LI+ K I + L + +Q++K V + + + E+ G
Sbjct: 752 ET---GLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDG 808
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLR--NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
+ S L A +V K+K L ++V+ Q L +++ T+ + +++L
Sbjct: 809 KIKSVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLA 868
Query: 773 NTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
NT K +QD+ ES K + LE+ LKEK + E+ R
Sbjct: 869 NTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEK---ENELKRLEAM 925
Query: 833 LIEAGSAYIAKVEV---AFNKVKSLDAEIQQHKKKNVPR--EMEKIQEANDKLMEKQKQI 887
L E S +K ++ ++ K ++I+Q K++N + +E + E++K+I
Sbjct: 926 LKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEI 985
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK 947
L ++D+LKD + Q DL + +A + + +K L +K+N +K
Sbjct: 986 ----SGLWNELDSLKDAVEHQRKKNNDLREKNW--EAMEALASTEKM---LQDKVNKTSK 1036
Query: 948 EELNEKESLIIKQTKLFQQKAECTGALSELK--KSLKGFRNELEKSLS 993
E + E++ ++ ++ ++ S L + L GF + ++ ++
Sbjct: 1037 ERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMA 1084
Score = 46.8 bits (106), Expect = 5e-04
Identities = 130/703 (18%), Positives = 284/703 (40%), Gaps = 65/703 (9%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKL--QKQTAKLKEKEMIEEN--LKT 443
ENE ++ ++ + + +Q EQ + +L + K ++++ +++ ++++E+N LK
Sbjct: 526 ENE--VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 444 KEKQL---IVLKNKHKTALMELLGNVPEKDFAV--TINKFECEVRNEVXXXXXXXXXXXX 498
+ +Q I + EL + EKD + T + E R+ +
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE-RDRLTSKEEELKDIQN 642
Query: 499 XXXXLEAERKHIRESLNERRS---ELTKAEDKIYKACGT-----QPYDVTLSKYTTTVEK 550
L+AE + ++ NE+ + EL K + +Y + +S +
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKI 702
Query: 551 LQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXM-NVPGKL 609
L D+ L+S + + + + + + + E + V K
Sbjct: 703 LNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKE 762
Query: 610 EKVTEDLQRASAKKDEILSMKSL-NEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
E++ S+ E+ +K+ N++++ E +L+K I + D +IK++ E +E
Sbjct: 763 EELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVE--ELKKVIHEKDGKIKSVEELLEAE 820
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA-TA 727
+ + E+ + + + +QE++ + K E V E D+A T
Sbjct: 821 LLKVANKEKTVQLS---------ITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 871
Query: 728 KQV-DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
K + D +++ +L+ V+ + N + +E+ +E N K+++ + L+E
Sbjct: 872 KWLQDLQEENESLKAHVQEVAQH-NLKEASSASQFEELEIVLKEKENELKRLEAM--LKE 928
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ L S + +E LK++ + + +L++ S ++
Sbjct: 929 RESDLSSKTQLLQDVQDENKLFKSQIE-QLKQQNYQQASSFPPHEELLKVISEREKEISG 987
Query: 847 AFNKVKSL-DAEIQQHKKKNVPRE-----MEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+N++ SL DA Q KK N RE ME + L +K + +RQ + ++
Sbjct: 988 LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVEL 1047
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--------EELNE 952
E+ K+ K + NL + + ++K+ E +G + +E +E
Sbjct: 1048 EAKEVLKKLFPKVSVPSNLSYGEW---LHGFEKKAKECMAGTSGSEEVKVLEHKLKEADE 1104
Query: 953 KESLIIKQTKLFQQK-AECTGALSELKKSLKGFRNELEKSLS------KDIEKKFREKMY 1005
+L+ + + ++ AE G L +L++S++ N+ + + K ++ F
Sbjct: 1105 MHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQ 1164
Query: 1006 ELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMI--IREL 1046
EL ++ +KDI + ME + +ME + +REL
Sbjct: 1165 ELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVREL 1207
Score = 35.1 bits (77), Expect = 1.5
Identities = 77/392 (19%), Positives = 159/392 (40%), Gaps = 50/392 (12%)
Query: 608 KLEKVTEDLQR--ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETV 665
K ++V E ++ A K++ + +++ L+ + +L K D + L E
Sbjct: 407 KFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKT 466
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
++ ++ + A Q+ + +R +E+++ +K A E ++ L
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEA-----AQQDLQ-- 519
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLE 785
+K V + ++ +L +++ T ++L L E + K + + Q +VQDI+
Sbjct: 520 -SKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN 578
Query: 786 ES-KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
E+ K Q+Q + + L L + I K + +++ D
Sbjct: 579 EALKAQIQQ-----FHSQIAAQTSASVLAEELHKVIAEKDKQIKQTED------------ 621
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
SL +E + K E++ IQ N L + +++ Q L + E
Sbjct: 622 --------SLASERDRLTSKE--EELKDIQNMNFLLKAEVQKL----QALANEQAAAAHE 667
Query: 905 IAK--QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK 962
+ K Q VY +D L + Q +I+N ++ LN++ N K E+ + ++L+ +Q
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQ-NKALKSEVQKLQTLVSEQPN 726
Query: 963 --LFQQKAECTGALSELKKSLKGFRNELEKSL 992
+ +Q +C + E + LK LE L
Sbjct: 727 KDVVEQMEKC---IQEKDEKLKTVEELLETGL 755
>AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein.
Length = 1337
Score = 64.5 bits (150), Expect = 2e-09
Identities = 127/652 (19%), Positives = 274/652 (42%), Gaps = 66/652 (10%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTK 444
K E+ L E ++ + + + A +Y+++ D + K L+ LK+ ++ + + +
Sbjct: 441 KSVESALRQLEREKALLQHKNA--EYQRKADHEADKKRNLENDVNSLKD-QLEDLKKRNQ 497
Query: 445 EKQLIVLK-NKHKTALMELLGNV-PEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
Q+ K N+ + L E + E D A + K + E ++
Sbjct: 498 NSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCL 557
Query: 503 LE-AERKHIRESLN-------ERRSELTKAE---DKIYKACGTQPYDVTLSKYTTTVEKL 551
LE A+ K +E +N ERR +E D + CG + L + K+
Sbjct: 558 LETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEE---DLKNGKILLAKV 614
Query: 552 QDEQNVLQSSMFIINKYKGQLKDNSCCPL--CNRGFENESEXXXXXXXXXXXXMNVPGKL 609
+ E+ LQ + K K ++ + L + E E + +
Sbjct: 615 ELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESI 674
Query: 610 EKVTEDLQRASAKK---DEILSMKSLN-----EKITTLKDTEIPQLEKRIVDVDTQIKTL 661
E+ + + KK + L K N EK +L D ++ Q +++I ++ Q L
Sbjct: 675 EEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVL 734
Query: 662 NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT 721
NE V +T+ + + QK + D+ M + + +K K+ + +E ++ +M
Sbjct: 735 NEDVRNLTLKIEQETQKRCLTQN---DLKMQTQQVNTLKMSEKQLK--QENNHLMEMKMN 789
Query: 722 LDVATAK----QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK---KTKAKEELLNT 774
L+ A+ + D ++ L+++++ Q + +++ L E+ KTK +EL
Sbjct: 790 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK 849
Query: 775 QKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI----EAKTEVVRRN 830
++++QD + QL+ A KEKI E K + R
Sbjct: 850 KQELQD--ERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHK 907
Query: 831 RDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ------ 884
++L E A IA +E N+ + D ++K+ + +++ +QE +L +++
Sbjct: 908 QELTEK-DATIASLEET-NRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI 965
Query: 885 -----KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQ--KQDDE 937
KQ++T+R + T+ ++ L + + ++E KR D ++ ++ + + + + ++
Sbjct: 966 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK 1025
Query: 938 LNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
L +++ K ELNE ++ I +++++ + E L ++ R++L+
Sbjct: 1026 LTQQMIKYQK-ELNEMQAQIAEESQI---RIELQMTLDSKDSDIEQLRSQLQ 1073
Score = 42.7 bits (96), Expect = 0.008
Identities = 102/492 (20%), Positives = 217/492 (44%), Gaps = 64/492 (13%)
Query: 604 NVPGKLEKVTEDLQRASAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
++ G++ + EDL+ ++ L + L E+ T L + E +E +D+ Q+K +
Sbjct: 592 DLQGRICGLEEDLKNGKILLAKVELEKRQLQERFTDL-EKEKSNME---IDMTYQLKVIQ 647
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
+++E+ E E K T A+ D + I+E K+ EA+KE + E TL
Sbjct: 648 QSLEQE-----EAEHKATKARL--ADKNKIYESIEEAKS-----EAMKEMEKKLLEERTL 695
Query: 723 DVATAKQV-DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
+ + +++ S L +K +Q+K+N L ++K E++ N K++
Sbjct: 696 KQKVENLLLEAEKRCSLLDCDLKQSQQKINE-------LLKQKDVLNEDVRNLTLKIEQ- 747
Query: 782 VNLEESKKQL-QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAY 840
E K+ L Q+D + L+ +E K + ++N +L +
Sbjct: 748 ---ETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRK----- 799
Query: 841 IAKVEVAFNKVKSLD--AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + A ++K L E +Q+ ++ +++E ++ + K++ +Q L +
Sbjct: 800 --ERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDER 857
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQD--DELNEK-LNGINKEELNEKES 955
D+L ++ + + K D + L A+ ++ +K+ EL K + +K+EL EK++
Sbjct: 858 DSLAAQL-EITLTKAD-SEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDA 915
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
I L + T ++ L + N+L KD++++ ++ + ++ A K
Sbjct: 916 TI---ASLEETNRTLTSDVANLANEKEELNNKL-----KDVQEQL-SRLKDEEISAAAIK 966
Query: 1016 DIREYAVALDKCLMEFHREKMENINMIIRELWRK--IYRGNDIDYIEIKTEG---NLTVE 1070
+K L+ K + +N + + RK + RGND D + E ++ ++
Sbjct: 967 ------AQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELK 1020
Query: 1071 SERRKYDYRVVQ 1082
SER K ++++
Sbjct: 1021 SEREKLTQQMIK 1032
Score = 36.3 bits (80), Expect = 0.66
Identities = 61/334 (18%), Positives = 135/334 (40%), Gaps = 26/334 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL-KEKEMIEENLKTKEK 446
+N+L ++ Q++N + + +Q +QE + L + L+KQ A+L KE++ + +K +
Sbjct: 756 QNDLKMQT--QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQD 813
Query: 447 QLIV---LKNKHKTALMELLGNVPEK-DFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
QL +KT + EL EK + + + E+++E
Sbjct: 814 QLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADS 873
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
+ R E ++ E E +I + ++T + T+ L++ L S +
Sbjct: 874 EQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELT--EKDATIASLEETNRTLTSDV 931
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEK--VTEDLQRAS 620
+ K +L N ++ E + + EK +TE +
Sbjct: 932 ANLANEKEEL---------NNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQ 982
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT----LNETVEEITMSLIEPE 676
A +++ + + E + DT++ + EK + ++K+ L + + + L E +
Sbjct: 983 A-VNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQ 1041
Query: 677 QKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAV 709
++ QI ++ M LD +I+ + + +A+
Sbjct: 1042 AQIAEESQIRIELQMTLDSKDSDIEQLRSQLQAL 1075
>AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein.
Length = 1428
Score = 64.5 bits (150), Expect = 2e-09
Identities = 127/652 (19%), Positives = 274/652 (42%), Gaps = 66/652 (10%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTK 444
K E+ L E ++ + + + A +Y+++ D + K L+ LK+ ++ + + +
Sbjct: 532 KSVESALRQLEREKALLQHKNA--EYQRKADHEADKKRNLENDVNSLKD-QLEDLKKRNQ 588
Query: 445 EKQLIVLK-NKHKTALMELLGNV-PEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
Q+ K N+ + L E + E D A + K + E ++
Sbjct: 589 NSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLESNNRDLQDKNCL 648
Query: 503 LE-AERKHIRESLN-------ERRSELTKAE---DKIYKACGTQPYDVTLSKYTTTVEKL 551
LE A+ K +E +N ERR +E D + CG + L + K+
Sbjct: 649 LETAKLKLEKEFINLQSALESERRDRTHGSEIINDLQGRICGLEE---DLKNGKILLAKV 705
Query: 552 QDEQNVLQSSMFIINKYKGQLKDNSCCPL--CNRGFENESEXXXXXXXXXXXXMNVPGKL 609
+ E+ LQ + K K ++ + L + E E + +
Sbjct: 706 ELEKRQLQERFTDLEKEKSNMEIDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESI 765
Query: 610 EKVTEDLQRASAKK---DEILSMKSLN-----EKITTLKDTEIPQLEKRIVDVDTQIKTL 661
E+ + + KK + L K N EK +L D ++ Q +++I ++ Q L
Sbjct: 766 EEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINELLKQKDVL 825
Query: 662 NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT 721
NE V +T+ + + QK + D+ M + + +K K+ + +E ++ +M
Sbjct: 826 NEDVRNLTLKIEQETQKRCLTQN---DLKMQTQQVNTLKMSEKQLK--QENNHLMEMKMN 880
Query: 722 LDVATAK----QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK---KTKAKEELLNT 774
L+ A+ + D ++ L+++++ Q + +++ L E+ KTK +EL
Sbjct: 881 LEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQK 940
Query: 775 QKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI----EAKTEVVRRN 830
++++QD + QL+ A KEKI E K + R
Sbjct: 941 KQELQD--ERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHK 998
Query: 831 RDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ------ 884
++L E A IA +E N+ + D ++K+ + +++ +QE +L +++
Sbjct: 999 QELTEK-DATIASLEET-NRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAI 1056
Query: 885 -----KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQ--KQDDE 937
KQ++T+R + T+ ++ L + + ++E KR D ++ ++ + + + + ++
Sbjct: 1057 KAQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREK 1116
Query: 938 LNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
L +++ K ELNE ++ I +++++ + E L ++ R++L+
Sbjct: 1117 LTQQMIKYQK-ELNEMQAQIAEESQI---RIELQMTLDSKDSDIEQLRSQLQ 1164
Score = 43.2 bits (97), Expect = 0.006
Identities = 139/715 (19%), Positives = 293/715 (40%), Gaps = 84/715 (11%)
Query: 386 QAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI----TKLQKQTAKLKEKEMIEENL 441
Q+ +E Q+++ E+ + Q +EL QK T+L+K +L+E+ + +++
Sbjct: 475 QSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNTRLEKTAKELEEEITLRKSV 534
Query: 442 KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
++ +QL + K L K K E
Sbjct: 535 ESALRQL----EREKALLQHKNAEYQRKADHEADKKRNLENDVNSLKDQLEDLKKRNQNS 590
Query: 502 XLEAER-KHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQS 560
+ E+ ++ L+E + L D + TQ ++ + +++L+ LQ
Sbjct: 591 QISTEKVNQLQRQLDETNALLRTESDTAARLRKTQ------AESSKQIQQLESNNRDLQD 644
Query: 561 SMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS 620
++ K +L+ N ESE ++ G++ + EDL+
Sbjct: 645 KNCLLETAKLKLEKE----FINLQSALESERRDRTHGSEIIN-DLQGRICGLEEDLKNGK 699
Query: 621 AKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ L + L E+ T L + E +E +D+ Q+K + +++E+ E E K
Sbjct: 700 ILLAKVELEKRQLQERFTDL-EKEKSNME---IDMTYQLKVIQQSLEQE-----EAEHKA 750
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV-DFKQKIST 738
T A+ D + I+E K+ EA+KE + E TL + + +++ S
Sbjct: 751 TKARL--ADKNKIYESIEEAKS-----EAMKEMEKKLLEERTLKQKVENLLLEAEKRCSL 803
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQL-QSDCXX 797
L +K +Q+K+N L ++K E++ N K++ E K+ L Q+D
Sbjct: 804 LDCDLKQSQQKINE-------LLKQKDVLNEDVRNLTLKIEQ----ETQKRCLTQNDLKM 852
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD-- 855
+ L+ +E K + ++N +L + + + A ++K L
Sbjct: 853 QTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRK-------ERQDADGQMKELQDQ 905
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
E +Q+ ++ +++E ++ + K++ +Q L + D+L ++ + + K D
Sbjct: 906 LEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQL-EITLTKAD- 963
Query: 916 DDNLCLRKAQTDITNWQKQD--DELNEK-LNGINKEELNEKESLIIKQTKLFQQKAECTG 972
+ L A+ ++ +K+ EL K + +K+EL EK++ I L + T
Sbjct: 964 SEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATI---ASLEETNRTLTS 1020
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
++ L + N+L KD++++ ++ + ++ A K +K L+
Sbjct: 1021 DVANLANEKEELNNKL-----KDVQEQL-SRLKDEEISAAAIK------AQFEKQLLTER 1068
Query: 1033 REKMENINMIIRELWRK--IYRGNDIDYIEIKTEG---NLTVESERRKYDYRVVQ 1082
K + +N + + RK + RGND D + E ++ ++SER K ++++
Sbjct: 1069 TLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIK 1123
Score = 36.3 bits (80), Expect = 0.66
Identities = 61/334 (18%), Positives = 135/334 (40%), Gaps = 26/334 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL-KEKEMIEENLKTKEK 446
+N+L ++ Q++N + + +Q +QE + L + L+KQ A+L KE++ + +K +
Sbjct: 847 QNDLKMQT--QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQD 904
Query: 447 QLIV---LKNKHKTALMELLGNVPEK-DFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
QL +KT + EL EK + + + E+++E
Sbjct: 905 QLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADS 964
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
+ R E ++ E E +I + ++T + T+ L++ L S +
Sbjct: 965 EQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELT--EKDATIASLEETNRTLTSDV 1022
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEK--VTEDLQRAS 620
+ K +L N ++ E + + EK +TE +
Sbjct: 1023 ANLANEKEEL---------NNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQ 1073
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT----LNETVEEITMSLIEPE 676
A +++ + + E + DT++ + EK + ++K+ L + + + L E +
Sbjct: 1074 A-VNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQ 1132
Query: 677 QKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAV 709
++ QI ++ M LD +I+ + + +A+
Sbjct: 1133 AQIAEESQIRIELQMTLDSKDSDIEQLRSQLQAL 1166
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 64.1 bits (149), Expect = 3e-09
Identities = 177/918 (19%), Positives = 364/918 (39%), Gaps = 69/918 (7%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLES-QNQEKIDKRNEQIVE 273
++AK +EL +K T E E++ E+ ++ K IL E Q + ++ E++
Sbjct: 854 LQAKDEELLKVKEKQTKVEGELEEM--ERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 911
Query: 274 --TAKIAEIENIT-EVQTNEEAENATKTILEKVESLKSDHKVQ--KSQADEEEKKAQGFV 328
AK E+E I ++++ E E IL+ E K +Q + Q DEEE Q
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQN-EKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 329 DECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHK-QA 387
E + + ++ K +
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEK 446
+ E+ I + ++ + ++EK ++ E+ +L + T LQ Q A+L+ + + ++ L KE+
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Query: 447 QL----------IVLKNKHKTALMELLGNVPE--KDFA---VTINKFECEVRNEVXXXXX 491
+L + KN + EL + E +DF + NK E + R ++
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR-DLSEELE 1149
Query: 492 XXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKL 551
A ++ +R + +EL KA ++ K Q D+ ++ T +E+L
Sbjct: 1150 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR-QRHATALEEL 1208
Query: 552 QDEQNVLQSSMFIINKYKGQLK-DN---SCCPLCNRGFENESEXXXXXXXXXXXXMNVPG 607
++ + + K K L+ DN +C + + ESE ++
Sbjct: 1209 SEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA-- 1266
Query: 608 KLEKVTE-DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE--KRIVDVDTQIKTLNET 664
KV+E D R + L+ T L++ E ++ K +++Q++ E
Sbjct: 1267 ---KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1323
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDVDSEMTLD 723
++E T + ++ ++ + +E K + K+ A++ Q D ++ D
Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 724 VATAKQVDFKQKISTLRNRVKTTQK---KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD 780
+ T + ++ +K L++ +Q+ K A++K +T + + + ++ + Q
Sbjct: 1384 LGTIESLEEAKK-KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQV 1442
Query: 781 IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAY 840
NLE+ +K+ E +EK + R + +EA +
Sbjct: 1443 ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF 1502
Query: 841 IAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+ NK D E K +V + + +++++ L ++ +++ T +++
Sbjct: 1503 ERQ-----NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT-------QLEE 1550
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE--ELNEKESLII 958
L+DE+ E K L+ N+ KAQ + + Q +D++ EK + K+ EL +
Sbjct: 1551 LEDELQATEDAKLRLEVNMQAMKAQFE-RDLQTRDEQNEEKKRLLIKQVRELEAELEDER 1609
Query: 959 KQTKL-FQQKAECTGALSELKKSLKG---FRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
KQ L K + L +L+ ++ R+E+ K L K ++ + ++ EL +A
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK-LQAQMKDYQRELEEARASR 1668
Query: 1015 KDIREYAVALDKCLMEFHREKME-NINMIIRELWRK---IYRGNDIDYIEIKTEGNLTVE 1070
+I + +K L E ++ + E R+ R D I G +
Sbjct: 1669 DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALL 1728
Query: 1071 SERRKYDYRVVQSKNGVE 1088
E+R+ + R+ Q + +E
Sbjct: 1729 DEKRRLEARIAQLEEELE 1746
Score = 56.4 bits (130), Expect = 6e-07
Identities = 126/667 (18%), Positives = 277/667 (41%), Gaps = 57/667 (8%)
Query: 407 VEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN---KHKTALMELL 463
V + E+E+ +++ K++++ K+ E E+ E ++ K +QL+ KN + A EL
Sbjct: 847 VTRQEEELQAKDEELLKVKEKQTKV-EGEL--EEMERKHQQLLEEKNILAEQLQAETELF 903
Query: 464 GNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK 523
E + K E E + L+ E+K ++ + + +L +
Sbjct: 904 AEAEEMRARLAAKKQELE--EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961
Query: 524 AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL--QSSMFIINKYKGQLKDNSCCPLC 581
E K Q VT ++K+++E +L Q+S FI K K ++D C
Sbjct: 962 EEGARQK---LQLEKVTAE---AKIKKMEEEILLLEDQNSKFI--KEKKLMEDR--IAEC 1011
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK 640
+ E E + LE E L++ + E+ K L+ + T L+
Sbjct: 1012 SSQLAEEEEKAKNLAKIRNKQEVMISDLE---ERLKKEEKTRQELEKAKRKLDGETTDLQ 1068
Query: 641 DTEIPQLEKRIVDVDTQIKTLNETVEEITM----SLIEPEQKMTTAKQIHGDMPMLDRYI 696
D +I +L+ +I ++ Q+ E ++ + + +++ + L
Sbjct: 1069 D-QIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1127
Query: 697 QEIKTVTKKFEAVKEQCGD------VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
+ K K E K + + E TLD A+Q ++ + K +++
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
Query: 751 NAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAI 809
H ++Q + ++ A EEL ++ + NLE++K+ L++D
Sbjct: 1188 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA-KVEVAFNKVKSLDAEIQQHKKKNVPR 868
E ++K++A+ + + + +A K N++ ++ +++ +KK +
Sbjct: 1248 AESE-HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1306
Query: 869 EME------KIQEANDKLME--KQKQIMTDR-QVLTKKIDTLKDEIAKQEVYKRDLDDNL 919
+ ++Q+ + L E +QK ++ R + L ++ ++L+++ ++E +++L+ +
Sbjct: 1307 AKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Query: 920 CLRKAQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSEL 977
++Q T +K DD+L E L K+ L + E+L ++ ++KA L +
Sbjct: 1367 LALQSQLADTK-KKVDDDLGTIESLEEAKKKLLKDAEAL----SQRLEEKALAYDKLEKT 1421
Query: 978 KKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHRE 1034
K L+ ++L L + + +K + A +K I YA D+ E +
Sbjct: 1422 KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK 1481
Query: 1035 KMENINM 1041
+ + +++
Sbjct: 1482 ETKALSL 1488
Score = 49.2 bits (112), Expect = 9e-05
Identities = 147/917 (16%), Positives = 358/917 (39%), Gaps = 82/917 (8%)
Query: 73 NRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVS 132
N + +V+ +++ +I ++ E ++ + A +K+ + L++ + +++ T D +
Sbjct: 1107 NNALKVVRELQAQIAELQE-DFESEKASRNKAEKQKRDLSEELEALKTELED---TLDTT 1162
Query: 133 SRCADLDILMHEELGVSKAILNSVVFCHQED-SSWPLDEGKKVKERFDEIFDADKYSDCL 191
+ +L +E+ K L H+ ++E +++ A ++ L
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANL 1222
Query: 192 DR----LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE----- 242
++ L+ K+ A +K+L+ + K+K+L+ ++ + E +++ E
Sbjct: 1223 EKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA 1282
Query: 243 -KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILE 301
K NE++ N LLE ++ I + +++ + + + + +T ++ +++ +
Sbjct: 1283 SKLQNELD-NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR--IR 1339
Query: 302 KVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDIT 361
++E K+ + Q+ + +E K + V +S +
Sbjct: 1340 QLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLK 1399
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
A + + EL ++ +++ + E++ + Q +
Sbjct: 1400 DAEALSQRLEEKALAYDKLEKTKNRLQQEL--DDLTVDLDHQRQVASNLEKKQKKFDQLL 1457
Query: 422 TKLQKQTAKL-KEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFEC 480
+ + +A+ +E++ E + KE + + L AL E L K+ NK
Sbjct: 1458 AEEKSISARYAEERDRAEAEAREKETKALSLAR----ALEEAL---EAKEEFERQNK--- 1507
Query: 481 EVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-PYDV 539
++R ++ LE ++ + + + E R++L + ED++ + +V
Sbjct: 1508 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 1567
Query: 540 TLSKYTTTVEK---LQDEQNVLQSSMFI--INKYKGQLKDN-----------SCCPLCNR 583
+ E+ +DEQN + + I + + + +L+D + +
Sbjct: 1568 NMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
Query: 584 GFENESEXXXXXXXXXXXXMN-VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDT 642
E + E + + +++ +L+ A A +DEI + +EK +
Sbjct: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687
Query: 643 EIPQLEKRIVDVDTQIK----TLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE 698
EI QL++ + + + +E +EIT S + +++ + L+ +E
Sbjct: 1688 EILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE---EE 1744
Query: 699 IKTVTKKFEAVKEQCGDVDSEM-TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKL 757
++ E + ++ ++ TL+ A + QK R +++ K+L A ++L
Sbjct: 1745 LEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQEL 1804
Query: 758 QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALK 817
+ + K KA L + I LEE QL+ + + E LK
Sbjct: 1805 EGAVKSKFKATISALEAK-----IGQLEE---QLEQE----AKERAAANKLVRRTEKKLK 1852
Query: 818 EKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
E I + E RR+ D Y ++E A ++K L ++++ ++ E + +
Sbjct: 1853 E-IFMQVEDERRHAD------QYKEQMEKANARMKQLKRQLEEAEE-----EATRANASR 1900
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDE 937
KL + + L++++ TLK+ + + R+ + + + DD+
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS-SSRSGRRQLHLEGASLELSDDD 1959
Query: 938 LNEKLNGINKEELNEKE 954
K + +N+ + + E
Sbjct: 1960 TESKTSDVNETQPPQSE 1976
Score = 32.7 bits (71), Expect = 8.2
Identities = 44/218 (20%), Positives = 98/218 (44%), Gaps = 14/218 (6%)
Query: 892 QVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELN 951
+V TK L+ ++E+ +D ++ L +++ QT + ++ + +++L EE N
Sbjct: 836 RVFTKVKPLLQVTRQEEELQAKD-EELLKVKEKQTKVEGELEEMERKHQQL----LEEKN 890
Query: 952 EKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK----KFREKMYEL 1007
+ +T+LF + E L+ K+ L+ ++LE + ++ E+ + +K +
Sbjct: 891 ILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQA 950
Query: 1008 HVTKAIDK-DIREYA---VALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT 1063
H+ ++ D E A + L+K E +KME +++ + K + + I
Sbjct: 951 HIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE 1010
Query: 1064 EGNLTVESERRKYDYRVVQSKNGVEI-DMRGRCSAGQK 1100
+ E E + + +++K V I D+ R +K
Sbjct: 1011 CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEK 1048
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 64.1 bits (149), Expect = 3e-09
Identities = 177/918 (19%), Positives = 364/918 (39%), Gaps = 69/918 (7%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLES-QNQEKIDKRNEQIVE 273
++AK +EL +K T E E++ E+ ++ K IL E Q + ++ E++
Sbjct: 854 LQAKDEELLKVKEKQTKVEGELEEM--ERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 911
Query: 274 --TAKIAEIENIT-EVQTNEEAENATKTILEKVESLKSDHKVQ--KSQADEEEKKAQGFV 328
AK E+E I ++++ E E IL+ E K +Q + Q DEEE Q
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQN-EKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 329 DECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHK-QA 387
E + + ++ K +
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEK 446
+ E+ I + ++ + ++EK ++ E+ +L + T LQ Q A+L+ + + ++ L KE+
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Query: 447 QL----------IVLKNKHKTALMELLGNVPE--KDFA---VTINKFECEVRNEVXXXXX 491
+L + KN + EL + E +DF + NK E + R ++
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR-DLSEELE 1149
Query: 492 XXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKL 551
A ++ +R + +EL KA ++ K Q D+ ++ T +E+L
Sbjct: 1150 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR-QRHATALEEL 1208
Query: 552 QDEQNVLQSSMFIINKYKGQLK-DN---SCCPLCNRGFENESEXXXXXXXXXXXXMNVPG 607
++ + + K K L+ DN +C + + ESE ++
Sbjct: 1209 SEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA-- 1266
Query: 608 KLEKVTE-DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE--KRIVDVDTQIKTLNET 664
KV+E D R + L+ T L++ E ++ K +++Q++ E
Sbjct: 1267 ---KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1323
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDVDSEMTLD 723
++E T + ++ ++ + +E K + K+ A++ Q D ++ D
Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 724 VATAKQVDFKQKISTLRNRVKTTQK---KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD 780
+ T + ++ +K L++ +Q+ K A++K +T + + + ++ + Q
Sbjct: 1384 LGTIESLEEAKK-KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQV 1442
Query: 781 IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAY 840
NLE+ +K+ E +EK + R + +EA +
Sbjct: 1443 ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF 1502
Query: 841 IAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+ NK D E K +V + + +++++ L ++ +++ T +++
Sbjct: 1503 ERQ-----NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT-------QLEE 1550
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE--ELNEKESLII 958
L+DE+ E K L+ N+ KAQ + + Q +D++ EK + K+ EL +
Sbjct: 1551 LEDELQATEDAKLRLEVNMQAMKAQFE-RDLQTRDEQNEEKKRLLIKQVRELEAELEDER 1609
Query: 959 KQTKL-FQQKAECTGALSELKKSLKG---FRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
KQ L K + L +L+ ++ R+E+ K L K ++ + ++ EL +A
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK-LQAQMKDYQRELEEARASR 1668
Query: 1015 KDIREYAVALDKCLMEFHREKME-NINMIIRELWRK---IYRGNDIDYIEIKTEGNLTVE 1070
+I + +K L E ++ + E R+ R D I G +
Sbjct: 1669 DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALL 1728
Query: 1071 SERRKYDYRVVQSKNGVE 1088
E+R+ + R+ Q + +E
Sbjct: 1729 DEKRRLEARIAQLEEELE 1746
Score = 56.4 bits (130), Expect = 6e-07
Identities = 126/667 (18%), Positives = 277/667 (41%), Gaps = 57/667 (8%)
Query: 407 VEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN---KHKTALMELL 463
V + E+E+ +++ K++++ K+ E E+ E ++ K +QL+ KN + A EL
Sbjct: 847 VTRQEEELQAKDEELLKVKEKQTKV-EGEL--EEMERKHQQLLEEKNILAEQLQAETELF 903
Query: 464 GNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK 523
E + K E E + L+ E+K ++ + + +L +
Sbjct: 904 AEAEEMRARLAAKKQELE--EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961
Query: 524 AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL--QSSMFIINKYKGQLKDNSCCPLC 581
E K Q VT ++K+++E +L Q+S FI K K ++D C
Sbjct: 962 EEGARQK---LQLEKVTAE---AKIKKMEEEILLLEDQNSKFI--KEKKLMEDR--IAEC 1011
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK 640
+ E E + LE E L++ + E+ K L+ + T L+
Sbjct: 1012 SSQLAEEEEKAKNLAKIRNKQEVMISDLE---ERLKKEEKTRQELEKAKRKLDGETTDLQ 1068
Query: 641 DTEIPQLEKRIVDVDTQIKTLNETVEEITM----SLIEPEQKMTTAKQIHGDMPMLDRYI 696
D +I +L+ +I ++ Q+ E ++ + + +++ + L
Sbjct: 1069 D-QIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1127
Query: 697 QEIKTVTKKFEAVKEQCGD------VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
+ K K E K + + E TLD A+Q ++ + K +++
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
Query: 751 NAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAI 809
H ++Q + ++ A EEL ++ + NLE++K+ L++D
Sbjct: 1188 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA-KVEVAFNKVKSLDAEIQQHKKKNVPR 868
E ++K++A+ + + + +A K N++ ++ +++ +KK +
Sbjct: 1248 AESE-HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1306
Query: 869 EME------KIQEANDKLME--KQKQIMTDR-QVLTKKIDTLKDEIAKQEVYKRDLDDNL 919
+ ++Q+ + L E +QK ++ R + L ++ ++L+++ ++E +++L+ +
Sbjct: 1307 AKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Query: 920 CLRKAQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSEL 977
++Q T +K DD+L E L K+ L + E+L ++ ++KA L +
Sbjct: 1367 LALQSQLADTK-KKVDDDLGTIESLEEAKKKLLKDAEAL----SQRLEEKALAYDKLEKT 1421
Query: 978 KKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHRE 1034
K L+ ++L L + + +K + A +K I YA D+ E +
Sbjct: 1422 KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK 1481
Query: 1035 KMENINM 1041
+ + +++
Sbjct: 1482 ETKALSL 1488
Score = 49.2 bits (112), Expect = 9e-05
Identities = 147/917 (16%), Positives = 358/917 (39%), Gaps = 82/917 (8%)
Query: 73 NRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVS 132
N + +V+ +++ +I ++ E ++ + A +K+ + L++ + +++ T D +
Sbjct: 1107 NNALKVVRELQAQIAELQE-DFESEKASRNKAEKQKRDLSEELEALKTELED---TLDTT 1162
Query: 133 SRCADLDILMHEELGVSKAILNSVVFCHQED-SSWPLDEGKKVKERFDEIFDADKYSDCL 191
+ +L +E+ K L H+ ++E +++ A ++ L
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANL 1222
Query: 192 DR----LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE----- 242
++ L+ K+ A +K+L+ + K+K+L+ ++ + E +++ E
Sbjct: 1223 EKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA 1282
Query: 243 -KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILE 301
K NE++ N LLE ++ I + +++ + + + + +T ++ +++ +
Sbjct: 1283 SKLQNELD-NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR--IR 1339
Query: 302 KVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDIT 361
++E K+ + Q+ + +E K + V +S +
Sbjct: 1340 QLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLK 1399
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
A + + EL ++ +++ + E++ + Q +
Sbjct: 1400 DAEALSQRLEEKALAYDKLEKTKNRLQQEL--DDLTVDLDHQRQVASNLEKKQKKFDQLL 1457
Query: 422 TKLQKQTAKL-KEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFEC 480
+ + +A+ +E++ E + KE + + L AL E L K+ NK
Sbjct: 1458 AEEKSISARYAEERDRAEAEAREKETKALSLAR----ALEEAL---EAKEEFERQNK--- 1507
Query: 481 EVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-PYDV 539
++R ++ LE ++ + + + E R++L + ED++ + +V
Sbjct: 1508 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 1567
Query: 540 TLSKYTTTVEK---LQDEQNVLQSSMFI--INKYKGQLKDN-----------SCCPLCNR 583
+ E+ +DEQN + + I + + + +L+D + +
Sbjct: 1568 NMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
Query: 584 GFENESEXXXXXXXXXXXXMN-VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDT 642
E + E + + +++ +L+ A A +DEI + +EK +
Sbjct: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687
Query: 643 EIPQLEKRIVDVDTQIK----TLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE 698
EI QL++ + + + +E +EIT S + +++ + L+ +E
Sbjct: 1688 EILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE---EE 1744
Query: 699 IKTVTKKFEAVKEQCGDVDSEM-TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKL 757
++ E + ++ ++ TL+ A + QK R +++ K+L A ++L
Sbjct: 1745 LEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQEL 1804
Query: 758 QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALK 817
+ + K KA L + I LEE QL+ + + E LK
Sbjct: 1805 EGAVKSKFKATISALEAK-----IGQLEE---QLEQE----AKERAAANKLVRRTEKKLK 1852
Query: 818 EKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
E I + E RR+ D Y ++E A ++K L ++++ ++ E + +
Sbjct: 1853 E-IFMQVEDERRHAD------QYKEQMEKANARMKQLKRQLEEAEE-----EATRANASR 1900
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDE 937
KL + + L++++ TLK+ + + R+ + + + DD+
Sbjct: 1901 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS-SSRSGRRQLHLEGASLELSDDD 1959
Query: 938 LNEKLNGINKEELNEKE 954
K + +N+ + + E
Sbjct: 1960 TESKTSDVNETQPPQSE 1976
Score = 32.7 bits (71), Expect = 8.2
Identities = 44/218 (20%), Positives = 98/218 (44%), Gaps = 14/218 (6%)
Query: 892 QVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELN 951
+V TK L+ ++E+ +D ++ L +++ QT + ++ + +++L EE N
Sbjct: 836 RVFTKVKPLLQVTRQEEELQAKD-EELLKVKEKQTKVEGELEEMERKHQQL----LEEKN 890
Query: 952 EKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK----KFREKMYEL 1007
+ +T+LF + E L+ K+ L+ ++LE + ++ E+ + +K +
Sbjct: 891 ILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQA 950
Query: 1008 HVTKAIDK-DIREYA---VALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT 1063
H+ ++ D E A + L+K E +KME +++ + K + + I
Sbjct: 951 HIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE 1010
Query: 1064 EGNLTVESERRKYDYRVVQSKNGVEI-DMRGRCSAGQK 1100
+ E E + + +++K V I D+ R +K
Sbjct: 1011 CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEK 1048
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 64.1 bits (149), Expect = 3e-09
Identities = 177/918 (19%), Positives = 364/918 (39%), Gaps = 69/918 (7%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLES-QNQEKIDKRNEQIVE 273
++AK +EL +K T E E++ E+ ++ K IL E Q + ++ E++
Sbjct: 854 LQAKDEELLKVKEKQTKVEGELEEM--ERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 911
Query: 274 --TAKIAEIENIT-EVQTNEEAENATKTILEKVESLKSDHKVQ--KSQADEEEKKAQGFV 328
AK E+E I ++++ E E IL+ E K +Q + Q DEEE Q
Sbjct: 912 RLAAKKQELEEILHDLESRVEEEEERNQILQN-EKKKMQAHIQDLEEQLDEEEGARQKLQ 970
Query: 329 DECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHK-QA 387
E + + ++ K +
Sbjct: 971 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1030
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEK 446
+ E+ I + ++ + ++EK ++ E+ +L + T LQ Q A+L+ + + ++ L KE+
Sbjct: 1031 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1090
Query: 447 QL----------IVLKNKHKTALMELLGNVPE--KDFA---VTINKFECEVRNEVXXXXX 491
+L + KN + EL + E +DF + NK E + R ++
Sbjct: 1091 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR-DLSEELE 1149
Query: 492 XXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKL 551
A ++ +R + +EL KA ++ K Q D+ ++ T +E+L
Sbjct: 1150 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR-QRHATALEEL 1208
Query: 552 QDEQNVLQSSMFIINKYKGQLK-DN---SCCPLCNRGFENESEXXXXXXXXXXXXMNVPG 607
++ + + K K L+ DN +C + + ESE ++
Sbjct: 1209 SEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA-- 1266
Query: 608 KLEKVTE-DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE--KRIVDVDTQIKTLNET 664
KV+E D R + L+ T L++ E ++ K +++Q++ E
Sbjct: 1267 ---KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1323
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDVDSEMTLD 723
++E T + ++ ++ + +E K + K+ A++ Q D ++ D
Sbjct: 1324 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1383
Query: 724 VATAKQVDFKQKISTLRNRVKTTQK---KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD 780
+ T + ++ +K L++ +Q+ K A++K +T + + + ++ + Q
Sbjct: 1384 LGTIESLEEAKK-KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEPDDLTVDLDHQRQV 1442
Query: 781 IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAY 840
NLE+ +K+ E +EK + R + +EA +
Sbjct: 1443 ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF 1502
Query: 841 IAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+ NK D E K +V + + +++++ L ++ +++ T +++
Sbjct: 1503 ERQ-----NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT-------QLEE 1550
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE--ELNEKESLII 958
L+DE+ E K L+ N+ KAQ + + Q +D++ EK + K+ EL +
Sbjct: 1551 LEDELQATEDAKLRLEVNMQAMKAQFE-RDLQTRDEQNEEKKRLLIKQVRELEAELEDER 1609
Query: 959 KQTKL-FQQKAECTGALSELKKSLKG---FRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
KQ L K + L +L+ ++ R+E+ K L K ++ + ++ EL +A
Sbjct: 1610 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK-LQAQMKDYQRELEEARASR 1668
Query: 1015 KDIREYAVALDKCLMEFHREKME-NINMIIRELWRK---IYRGNDIDYIEIKTEGNLTVE 1070
+I + +K L E ++ + E R+ R D I G +
Sbjct: 1669 DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALL 1728
Query: 1071 SERRKYDYRVVQSKNGVE 1088
E+R+ + R+ Q + +E
Sbjct: 1729 DEKRRLEARIAQLEEELE 1746
Score = 56.4 bits (130), Expect = 6e-07
Identities = 126/667 (18%), Positives = 277/667 (41%), Gaps = 57/667 (8%)
Query: 407 VEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN---KHKTALMELL 463
V + E+E+ +++ K++++ K+ E E+ E ++ K +QL+ KN + A EL
Sbjct: 847 VTRQEEELQAKDEELLKVKEKQTKV-EGEL--EEMERKHQQLLEEKNILAEQLQAETELF 903
Query: 464 GNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK 523
E + K E E + L+ E+K ++ + + +L +
Sbjct: 904 AEAEEMRARLAAKKQELE--EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961
Query: 524 AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL--QSSMFIINKYKGQLKDNSCCPLC 581
E K Q VT ++K+++E +L Q+S FI K K ++D C
Sbjct: 962 EEGARQK---LQLEKVTAE---AKIKKMEEEILLLEDQNSKFI--KEKKLMEDR--IAEC 1011
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK 640
+ E E + LE E L++ + E+ K L+ + T L+
Sbjct: 1012 SSQLAEEEEKAKNLAKIRNKQEVMISDLE---ERLKKEEKTRQELEKAKRKLDGETTDLQ 1068
Query: 641 DTEIPQLEKRIVDVDTQIKTLNETVEEITM----SLIEPEQKMTTAKQIHGDMPMLDRYI 696
D +I +L+ +I ++ Q+ E ++ + + +++ + L
Sbjct: 1069 D-QIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1127
Query: 697 QEIKTVTKKFEAVKEQCGD------VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
+ K K E K + + E TLD A+Q ++ + K +++
Sbjct: 1128 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1187
Query: 751 NAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAI 809
H ++Q + ++ A EEL ++ + NLE++K+ L++D
Sbjct: 1188 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1247
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA-KVEVAFNKVKSLDAEIQQHKKKNVPR 868
E ++K++A+ + + + +A K N++ ++ +++ +KK +
Sbjct: 1248 AESE-HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1306
Query: 869 EME------KIQEANDKLME--KQKQIMTDR-QVLTKKIDTLKDEIAKQEVYKRDLDDNL 919
+ ++Q+ + L E +QK ++ R + L ++ ++L+++ ++E +++L+ +
Sbjct: 1307 AKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Query: 920 CLRKAQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSEL 977
++Q T +K DD+L E L K+ L + E+L ++ ++KA L +
Sbjct: 1367 LALQSQLADTK-KKVDDDLGTIESLEEAKKKLLKDAEAL----SQRLEEKALAYDKLEKT 1421
Query: 978 KKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHRE 1034
K L+ ++L L + + +K + A +K I YA D+ E +
Sbjct: 1422 KNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK 1481
Query: 1035 KMENINM 1041
+ + +++
Sbjct: 1482 ETKALSL 1488
Score = 46.4 bits (105), Expect = 6e-04
Identities = 144/913 (15%), Positives = 348/913 (38%), Gaps = 74/913 (8%)
Query: 73 NRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVS 132
N + +V+ +++ +I ++ E ++ + A +K+ + L++ + +++ T D +
Sbjct: 1107 NNALKVVRELQAQIAELQE-DFESEKASRNKAEKQKRDLSEELEALKTELED---TLDTT 1162
Query: 133 SRCADLDILMHEELGVSKAILNSVVFCHQED-SSWPLDEGKKVKERFDEIFDADKYSDCL 191
+ +L +E+ K L H+ ++E +++ A ++ L
Sbjct: 1163 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANL 1222
Query: 192 DR----LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNE 247
++ L+ K+ A +K+L+ + K+K+L+ ++ + E +++ E +
Sbjct: 1223 EKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA 1282
Query: 248 IEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLK 307
+ + S E+ +K+ + + A E + + +E + ++ L+
Sbjct: 1283 SKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLE 1342
Query: 308 SDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSX 367
+ + Q +EEE+ + + + +Q +
Sbjct: 1343 EEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAE 1402
Query: 368 XXXXXXXXXXXXXXXXHKQAENELNIE--ECQQEINEDEKAVEQYEQEMDELSQKITKLQ 425
K +N L E + +++ + E++ + Q + + +
Sbjct: 1403 ALSQRLEEKALAYDKLEK-TKNRLQQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEK 1461
Query: 426 KQTAKL-KEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRN 484
+A+ +E++ E + KE + + L AL E L K+ NK ++R
Sbjct: 1462 SISARYAEERDRAEAEAREKETKALSLAR----ALEEAL---EAKEEFERQNK---QLRA 1511
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-PYDVTLSK 543
++ LE ++ + + + E R++L + ED++ + +V +
Sbjct: 1512 DMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQA 1571
Query: 544 YTTTVEK---LQDEQNVLQSSMFI--INKYKGQLKDN-----------SCCPLCNRGFEN 587
E+ +DEQN + + I + + + +L+D + + E
Sbjct: 1572 MKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEA 1631
Query: 588 ESEXXXXXXXXXXXXMN-VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQ 646
+ E + + +++ +L+ A A +DEI + +EK + EI Q
Sbjct: 1632 QIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQ 1691
Query: 647 LEKRIVDVDTQIK----TLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTV 702
L++ + + + +E +EIT S + +++ + L+ +E++
Sbjct: 1692 LQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE---EELEEE 1748
Query: 703 TKKFEAVKEQCGDVDSEM-TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLY 761
E + ++ ++ TL+ A + QK R +++ K+L A ++L+
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAV 1808
Query: 762 EKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE 821
+ K KA L + I LEE QL+ + + E LKE I
Sbjct: 1809 KSKFKATISALEAK-----IGQLEE---QLEQE----AKERAAANKLVRRTEKKLKE-IF 1855
Query: 822 AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLM 881
+ E RR+ D Y ++E A ++K L ++++ ++ E + + KL
Sbjct: 1856 MQVEDERRHAD------QYKEQMEKANARMKQLKRQLEEAEE-----EATRANASRRKLQ 1904
Query: 882 EKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK 941
+ + L++++ TLK+ + + R+ + + + DD+ K
Sbjct: 1905 RELDDATEANEGLSREVSTLKNRLRRGGPISFS-SSRSGRRQLHLEGASLELSDDDTESK 1963
Query: 942 LNGINKEELNEKE 954
+ +N+ + + E
Sbjct: 1964 TSDVNETQPPQSE 1976
Score = 32.7 bits (71), Expect = 8.2
Identities = 44/218 (20%), Positives = 98/218 (44%), Gaps = 14/218 (6%)
Query: 892 QVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELN 951
+V TK L+ ++E+ +D ++ L +++ QT + ++ + +++L EE N
Sbjct: 836 RVFTKVKPLLQVTRQEEELQAKD-EELLKVKEKQTKVEGELEEMERKHQQL----LEEKN 890
Query: 952 EKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK----KFREKMYEL 1007
+ +T+LF + E L+ K+ L+ ++LE + ++ E+ + +K +
Sbjct: 891 ILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQA 950
Query: 1008 HVTKAIDK-DIREYA---VALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT 1063
H+ ++ D E A + L+K E +KME +++ + K + + I
Sbjct: 951 HIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE 1010
Query: 1064 EGNLTVESERRKYDYRVVQSKNGVEI-DMRGRCSAGQK 1100
+ E E + + +++K V I D+ R +K
Sbjct: 1011 CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEK 1048
>AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 protein.
Length = 1357
Score = 64.1 bits (149), Expect = 3e-09
Identities = 128/630 (20%), Positives = 273/630 (43%), Gaps = 72/630 (11%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKL--QKQTAKLKEKEMIEEN--LKT 443
ENE ++ ++ + + +Q EQ + +L + K ++++ +++ ++++E+N LK
Sbjct: 526 ENE--VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 444 KEKQL---IVLKNKHKTALMELLGNVPEKDFAV--TINKFECEVRNEVXXXXXXXXXXXX 498
+ +Q I + EL + EKD + T + E R+ +
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE-RDRLTSKEEELKDIQN 642
Query: 499 XXXXLEAERKHIRESLNERRS---ELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQ 555
L+AE + ++ NE+ + EL K + +Y V K E+LQ E
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVY---------VKDDKIRLLEEQLQHEI 693
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
+ I+N LK + L + +E KL+ V E
Sbjct: 694 SNKMEEFKILNDQNKALK-SEVQKL--QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEEL 750
Query: 616 LQ----RASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS 671
L+ + + K++E+ ++++ N +T E+ L+ + D Q+ + VEE+
Sbjct: 751 LETGLIQVATKEEELNAIRTENSSLTK----EVQDLKAKQND---QV-SFASLVEELKKV 802
Query: 672 LIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
+ E + K+ + +++ ++ + + ++ + ++ +A+KE+ G+V E A+Q+
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK------AQQL 856
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
K+ L+N +K ++++N ++ + E+K K +L NT K +QD+ ES K
Sbjct: 857 SITSKVQELQNLLKGKEEQMNT----MKAVLEEKEK---DLANTGKWLQDLQEENESLKA 909
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV---A 847
+ LE+ LKEK + E+ R L E S +K ++
Sbjct: 910 HVQEVAQHNLKEASSASQFEELEIVLKEK---ENELKRLEAMLKERESDLSSKTQLLQDV 966
Query: 848 FNKVKSLDAEIQQHKKKNVPR--EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
++ K ++I+Q K++N + +E + E++K+I L ++D+LKD +
Sbjct: 967 QDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEI----SGLWNELDSLKDAV 1022
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ 965
Q DL + +A + + +K L +K+N +KE + E++ ++ ++ +
Sbjct: 1023 EHQRKKNNDLREKNW--EAMEALASTEKM---LQDKVNKTSKERQQQVEAVELEAKEVLK 1077
Query: 966 QKAECTGALSELK--KSLKGFRNELEKSLS 993
+ S L + L GF + ++ ++
Sbjct: 1078 KLFPKVSVPSNLSYGEWLHGFEKKAKECMA 1107
Score = 54.0 bits (124), Expect = 3e-06
Identities = 93/465 (20%), Positives = 200/465 (43%), Gaps = 39/465 (8%)
Query: 612 VTEDLQRASAKKDEILSMKSLNEKITTL---KDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+T+++Q AK+++ +S SL E++ + KD +I +E+ + ++ +TV+++
Sbjct: 775 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDL 834
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA-TA 727
+ ++++ + + +QE++ + K E V E D+A T
Sbjct: 835 KQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 894
Query: 728 KQV-DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
K + D +++ +L+ V+ + N + +E+ +E N K+++ + L+E
Sbjct: 895 KWLQDLQEENESLKAHVQEVAQH-NLKEASSASQFEELEIVLKEKENELKRLEAM--LKE 951
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ L S + +E LK++ + + +L++ S ++
Sbjct: 952 RESDLSSKTQLLQDVQDENKLFKSQIE-QLKQQNYQQASSFPPHEELLKVISEREKEISG 1010
Query: 847 AFNKVKSL-DAEIQQHKKKNVPRE-----MEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+N++ SL DA Q KK N RE ME + L +K + +RQ + ++
Sbjct: 1011 LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVEL 1070
Query: 901 LKDEIAKQEVYKRDLDDNLCL--------RKAQTDI--TNWQKQDDELNEKLNGINKEEL 950
E+ K+ K + NL +KA+ + T+ ++ L KL +E
Sbjct: 1071 EAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKL-----KEA 1125
Query: 951 NEKESLIIKQTKLFQQ-KAECTGALSELKKSLKGFRNELEKSLS------KDIEKKFREK 1003
+E +L+ + + ++ AE G L +L++S++ N+ + + K ++ F
Sbjct: 1126 DEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSS 1185
Query: 1004 MYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMI--IREL 1046
EL ++ +KDI + ME + +ME + +REL
Sbjct: 1186 EQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVREL 1230
Score = 48.8 bits (111), Expect = 1e-04
Identities = 118/630 (18%), Positives = 252/630 (40%), Gaps = 56/630 (8%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN---LKTKEKQLIV 450
E+ Q EI+ + + + L ++ KLQ ++ K+++E+ ++ K+++L
Sbjct: 687 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 746
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
++ +T L+++ E + T N + EV +E +K I
Sbjct: 747 VEELLETGLIQVATKEEELNAIRTENS---SLTKEVQDLKAKQNDQVSFASLVEELKKVI 803
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-QNV-LQSSMFIINKY 568
E + +S E ++ K + T+ ++ L++E NV L+ + +
Sbjct: 804 HEKDGKIKSVEELLEAELLKVANKEK---TVQDLKQEIKALKEEIGNVQLEKAQQLSITS 860
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK-LEKVTEDLQRASAKKDEIL 627
K Q N +G E + + GK L+ + E+ + A E+
Sbjct: 861 KVQELQNLL-----KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEV- 914
Query: 628 SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG 687
+ +L E + ++ +LE + + + ++K L ++E E +++ Q+
Sbjct: 915 AQHNLKEASSA---SQFEELEIVLKEKENELKRLEAMLKE-------RESDLSSKTQLLQ 964
Query: 688 DMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK-ISTLRNRVKTT 746
D+ E K + E +K+Q S K + ++K IS L N + +
Sbjct: 965 DVQ------DENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSL 1018
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXX 806
+ + KK L EK +A E L +T+K +QD VN ++Q Q +
Sbjct: 1019 KDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVE--------- 1069
Query: 807 XAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV-EVAFNKVKSLDAEIQQHKKKN 865
+ EV +K+ K V N E + K E S + ++ +HK K
Sbjct: 1070 --LEAKEVL--KKLFPKVSVPS-NLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKE 1124
Query: 866 VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQ 925
EM + + EK K ++ + + + +K+ ++ + K D + + +++ Q
Sbjct: 1125 AD-EMHTLLQLE---CEKYKSVLAETEGILQKLQRSVEQEENKWKVKVD-ESHKTIKQMQ 1179
Query: 926 TDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFR 985
+ T+ +++ + L + I E+E L ++ K +++ + ELK L +
Sbjct: 1180 SSFTSSEQELERLRSENKDIENLR-REREHLEMELEKAEMERSTYVTEVRELKDLLTELQ 1238
Query: 986 NELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+L+ S S+ + + + + + + + K
Sbjct: 1239 KKLDDSYSEAVRQNEELNLLKAQLNETLTK 1268
Score = 46.8 bits (106), Expect = 5e-04
Identities = 121/642 (18%), Positives = 239/642 (37%), Gaps = 46/642 (7%)
Query: 64 ECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKK----KTKFQTLDSFL 119
+C + ++ E L + L V K+++L R+ ++L K+ K K SF
Sbjct: 735 KCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN-SSLTKEVQDLKAKQNDQVSFA 793
Query: 120 STVDESGKT-KDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERF 178
S V+E K + + ++ L+ EL +V QE + + G E+
Sbjct: 794 SLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKA 853
Query: 179 DEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
++ K + L L K +++ +K +LE + K L+D ++N S +
Sbjct: 854 QQLSITSKVQE-LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 912
Query: 238 KIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATK 297
++A ++F LE +EK + +++ K E + ++ Q ++ ++ K
Sbjct: 913 EVAQHNLKEASSASQFEELEIVLKEK-ENELKRLEAMLKERESDLSSKTQLLQDVQDENK 971
Query: 298 TILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXX 357
++E LK + Q S E+ + + E R
Sbjct: 972 LFKSQIEQLKQQNYQQASSFPPHEELLK-VISE-REKEISGLWNELDSLKDAVEHQRKKN 1029
Query: 358 XDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVE--------- 408
D+ N E + +E + E E K +
Sbjct: 1030 NDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNL 1089
Query: 409 QYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK---NKHKTALMELLGN 465
Y + + +K + T+ +E +++E LK ++ +L+ K+K+ L E G
Sbjct: 1090 SYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGI 1149
Query: 466 VPEKDFAVTI--NKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK 523
+ + +V NK++ +V LE R ++ N RR E
Sbjct: 1150 LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRR-EREH 1208
Query: 524 AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNR 583
E ++ KA ++ S Y T V +L+D LQ + + Y ++ N L
Sbjct: 1209 LEMELEKA------EMERSTYVTEVRELKDLLTELQKKLD--DSYSEAVRQNEELNLLKA 1260
Query: 584 GFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTE 643
+E V G L K + L+ +K +K+ + T +++++
Sbjct: 1261 QL---NETLTKLRTEQNERQKVAGDLHKAQQSLELIQSK-----IVKAAGDT-TVIENSD 1311
Query: 644 I-PQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ 684
+ P+ E + +T +LN+TV ++ L Q++T K+
Sbjct: 1312 VSPETESS--EKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1351
Score = 44.8 bits (101), Expect = 0.002
Identities = 154/846 (18%), Positives = 327/846 (38%), Gaps = 52/846 (6%)
Query: 89 AKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGV 148
AK+ +++ S L K+ Q L + + ++ K+ S + DIL E
Sbjct: 524 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMES-EQKRVNKEESLQMQVQDILEQNEALK 582
Query: 149 SKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLL 208
++ Q +S +E KV D+ + S +R + K+ + LK +
Sbjct: 583 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKE--EELKDI 640
Query: 209 ENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRN 268
+N +KA+ ++L+ + + E EK+ + S ++ +K LLE Q Q +I +
Sbjct: 641 QNMNFLLKAEVQKLQALANEQAAAAHELEKM---QQSVYVKDDKIRLLEEQLQHEISNKM 697
Query: 269 EQ--IVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQG 326
E+ I+ A + ++QT +E K ++E++E + K +K + EE + G
Sbjct: 698 EEFKILNDQNKALKSEVQKLQTLV-SEQPNKDVVEQMEKCIQE-KDEKLKTVEELLET-G 754
Query: 327 FVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQ 386
+ T+ +Q K
Sbjct: 755 LIQVA----TKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKI 810
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
E +E ++ EK V+ +QE+ L ++I +Q L++ + + K +E
Sbjct: 811 KSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQ-----LEKAQQLSITSKVQEL 865
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINKFE-CEVRNEVXXXXXXXXXXXXXXXXLEA 505
Q ++ + + M+ + EKD A T + + NE A
Sbjct: 866 QNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSA 925
Query: 506 ER-KHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFI 564
+ + + L E+ +EL + E + + + LS T ++ +QDE + +S +
Sbjct: 926 SQFEELEIVLKEKENELKRLEAMLKER------ESDLSSKTQLLQDVQDENKLFKSQIEQ 979
Query: 565 INKYKGQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASA 621
+ + Q + +S P L E E E V + +K DL+ +
Sbjct: 980 LKQQNYQ-QASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKK-NNDLREKNW 1037
Query: 622 KKDEILSM--KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ E L+ K L +K+ Q+E ++ +K L V + +L E
Sbjct: 1038 EAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVS-VPSNLSYGEWLH 1096
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD-FKQKIST 738
K+ M +E+K + K + E + E + + + QK+
Sbjct: 1097 GFEKKAKECMAGTSGS-EEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQR 1155
Query: 739 LRNRVKTTQK-KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXX 797
+ + K K++ +K ++ + T +++EL + + +DI NL ++ L+ +
Sbjct: 1156 SVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEK 1215
Query: 798 XXXXXXXXXXAITPLE---VALKEKI-EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKS 853
+ L+ L++K+ ++ +E VR+N +L + A++ K+++
Sbjct: 1216 AEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEEL----NLLKAQLNETLTKLRT 1271
Query: 854 LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
+Q++++ V ++ K Q++ + + K + D V+ + + E +++E
Sbjct: 1272 -----EQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSV 1326
Query: 914 DLDDNL 919
L+ +
Sbjct: 1327 SLNQTV 1332
Score = 35.9 bits (79), Expect = 0.88
Identities = 95/503 (18%), Positives = 205/503 (40%), Gaps = 56/503 (11%)
Query: 608 KLEKVTEDLQR--ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETV 665
K ++V E ++ A K++ + +++ L+ + +L K D + L E
Sbjct: 407 KFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKT 466
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
++ ++ + A Q+ + +R +E+++ +K A E ++ L
Sbjct: 467 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEA-----AQQDLQ-- 519
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLE 785
+K V + ++ +L +++ T ++L L E + K + + Q +VQDI+
Sbjct: 520 -SKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN 578
Query: 786 ES-KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
E+ K Q+Q + + L L + I K + +++ D
Sbjct: 579 EALKAQIQQ-----FHSQIAAQTSASVLAEELHKVIAEKDKQIKQTED------------ 621
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
SL +E + K E++ IQ N L + +++ Q L + E
Sbjct: 622 --------SLASERDRLTSKE--EELKDIQNMNFLLKAEVQKL----QALANEQAAAAHE 667
Query: 905 IAK--QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK 962
+ K Q VY +D L + Q +I+N ++ LN++ N K E+ + ++L+ +Q
Sbjct: 668 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQ-NKALKSEVQKLQTLVSEQPN 726
Query: 963 --LFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV-TKAIDKDIRE 1019
+ +Q +C + E + LK LE L + K+ E++ + ++ K++++
Sbjct: 727 KDVVEQMEKC---IQEKDEKLKTVEELLETGLIQVATKE--EELNAIRTENSSLTKEVQD 781
Query: 1020 YAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYR 1079
A + F +E + +I E KI ++ E+ N + K + +
Sbjct: 782 LK-AKQNDQVSF-ASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIK 839
Query: 1080 VVQSKNG-VEIDMRGRCSAGQKV 1101
++ + G V+++ + S KV
Sbjct: 840 ALKEEIGNVQLEKAQQLSITSKV 862
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 64.1 bits (149), Expect = 3e-09
Identities = 177/918 (19%), Positives = 364/918 (39%), Gaps = 69/918 (7%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLES-QNQEKIDKRNEQIVE 273
++AK +EL +K T E E++ E+ ++ K IL E Q + ++ E++
Sbjct: 896 LQAKDEELLKVKEKQTKVEGELEEM--ERKHQQLLEEKNILAEQLQAETELFAEAEEMRA 953
Query: 274 --TAKIAEIENIT-EVQTNEEAENATKTILEKVESLKSDHKVQ--KSQADEEEKKAQGFV 328
AK E+E I ++++ E E IL+ E K +Q + Q DEEE Q
Sbjct: 954 RLAAKKQELEEILHDLESRVEEEEERNQILQN-EKKKMQAHIQDLEEQLDEEEGARQKLQ 1012
Query: 329 DECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHK-QA 387
E + + ++ K +
Sbjct: 1013 LEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRN 1072
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEK 446
+ E+ I + ++ + ++EK ++ E+ +L + T LQ Q A+L+ + + ++ L KE+
Sbjct: 1073 KQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEE 1132
Query: 447 QL----------IVLKNKHKTALMELLGNVPE--KDFA---VTINKFECEVRNEVXXXXX 491
+L + KN + EL + E +DF + NK E + R ++
Sbjct: 1133 ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR-DLSEELE 1191
Query: 492 XXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKL 551
A ++ +R + +EL KA ++ K Q D+ ++ T +E+L
Sbjct: 1192 ALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMR-QRHATALEEL 1250
Query: 552 QDEQNVLQSSMFIINKYKGQLK-DN---SCCPLCNRGFENESEXXXXXXXXXXXXMNVPG 607
++ + + K K L+ DN +C + + ESE ++
Sbjct: 1251 SEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHA-- 1308
Query: 608 KLEKVTE-DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE--KRIVDVDTQIKTLNET 664
KV+E D R + L+ T L++ E ++ K +++Q++ E
Sbjct: 1309 ---KVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQEL 1365
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDVDSEMTLD 723
++E T + ++ ++ + +E K + K+ A++ Q D ++ D
Sbjct: 1366 LQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDD 1425
Query: 724 VATAKQVDFKQKISTLRNRVKTTQK---KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD 780
+ T + ++ +K L++ +Q+ K A++K +T + + + ++ + Q
Sbjct: 1426 LGTIESLEEAKK-KLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQV 1484
Query: 781 IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAY 840
NLE+ +K+ E +EK + R + +EA +
Sbjct: 1485 ASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEF 1544
Query: 841 IAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+ NK D E K +V + + +++++ L ++ +++ T +++
Sbjct: 1545 ERQ-----NKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRT-------QLEE 1592
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE--ELNEKESLII 958
L+DE+ E K L+ N+ KAQ + + Q +D++ EK + K+ EL +
Sbjct: 1593 LEDELQATEDAKLRLEVNMQAMKAQFE-RDLQTRDEQNEEKKRLLIKQVRELEAELEDER 1651
Query: 959 KQTKL-FQQKAECTGALSELKKSLKG---FRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
KQ L K + L +L+ ++ R+E+ K L K ++ + ++ EL +A
Sbjct: 1652 KQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRK-LQAQMKDYQRELEEARASR 1710
Query: 1015 KDIREYAVALDKCLMEFHREKME-NINMIIRELWRK---IYRGNDIDYIEIKTEGNLTVE 1070
+I + +K L E ++ + E R+ R D I G +
Sbjct: 1711 DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALL 1770
Query: 1071 SERRKYDYRVVQSKNGVE 1088
E+R+ + R+ Q + +E
Sbjct: 1771 DEKRRLEARIAQLEEELE 1788
Score = 56.4 bits (130), Expect = 6e-07
Identities = 126/667 (18%), Positives = 277/667 (41%), Gaps = 57/667 (8%)
Query: 407 VEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN---KHKTALMELL 463
V + E+E+ +++ K++++ K+ E E+ E ++ K +QL+ KN + A EL
Sbjct: 889 VTRQEEELQAKDEELLKVKEKQTKV-EGEL--EEMERKHQQLLEEKNILAEQLQAETELF 945
Query: 464 GNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK 523
E + K E E + L+ E+K ++ + + +L +
Sbjct: 946 AEAEEMRARLAAKKQELE--EILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 1003
Query: 524 AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL--QSSMFIINKYKGQLKDNSCCPLC 581
E K Q VT ++K+++E +L Q+S FI K K ++D C
Sbjct: 1004 EEGARQK---LQLEKVTAE---AKIKKMEEEILLLEDQNSKFI--KEKKLMEDR--IAEC 1053
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK 640
+ E E + LE E L++ + E+ K L+ + T L+
Sbjct: 1054 SSQLAEEEEKAKNLAKIRNKQEVMISDLE---ERLKKEEKTRQELEKAKRKLDGETTDLQ 1110
Query: 641 DTEIPQLEKRIVDVDTQIKTLNETVEEITM----SLIEPEQKMTTAKQIHGDMPMLDRYI 696
D +I +L+ +I ++ Q+ E ++ + + +++ + L
Sbjct: 1111 D-QIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDF 1169
Query: 697 QEIKTVTKKFEAVKEQCGD------VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
+ K K E K + + E TLD A+Q ++ + K +++
Sbjct: 1170 ESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEET 1229
Query: 751 NAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXXAI 809
H ++Q + ++ A EEL ++ + NLE++K+ L++D
Sbjct: 1230 KNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVK 1289
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA-KVEVAFNKVKSLDAEIQQHKKKNVPR 868
E ++K++A+ + + + +A K N++ ++ +++ +KK +
Sbjct: 1290 AESE-HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1348
Query: 869 EME------KIQEANDKLME--KQKQIMTDR-QVLTKKIDTLKDEIAKQEVYKRDLDDNL 919
+ ++Q+ + L E +QK ++ R + L ++ ++L+++ ++E +++L+ +
Sbjct: 1349 AKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1408
Query: 920 CLRKAQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSEL 977
++Q T +K DD+L E L K+ L + E+L ++ ++KA L +
Sbjct: 1409 LALQSQLADTK-KKVDDDLGTIESLEEAKKKLLKDAEAL----SQRLEEKALAYDKLEKT 1463
Query: 978 KKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHRE 1034
K L+ ++L L + + +K + A +K I YA D+ E +
Sbjct: 1464 KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREK 1523
Query: 1035 KMENINM 1041
+ + +++
Sbjct: 1524 ETKALSL 1530
Score = 49.2 bits (112), Expect = 9e-05
Identities = 147/917 (16%), Positives = 358/917 (39%), Gaps = 82/917 (8%)
Query: 73 NRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVS 132
N + +V+ +++ +I ++ E ++ + A +K+ + L++ + +++ T D +
Sbjct: 1149 NNALKVVRELQAQIAELQE-DFESEKASRNKAEKQKRDLSEELEALKTELED---TLDTT 1204
Query: 133 SRCADLDILMHEELGVSKAILNSVVFCHQED-SSWPLDEGKKVKERFDEIFDADKYSDCL 191
+ +L +E+ K L H+ ++E +++ A ++ L
Sbjct: 1205 AAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANL 1264
Query: 192 DR----LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE----- 242
++ L+ K+ A +K+L+ + K+K+L+ ++ + E +++ E
Sbjct: 1265 EKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKA 1324
Query: 243 -KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILE 301
K NE++ N LLE ++ I + +++ + + + + +T ++ +++ +
Sbjct: 1325 SKLQNELD-NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSR--IR 1381
Query: 302 KVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDIT 361
++E K+ + Q+ + +E K + V +S +
Sbjct: 1382 QLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLK 1441
Query: 362 SANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKI 421
A + + EL ++ +++ + E++ + Q +
Sbjct: 1442 DAEALSQRLEEKALAYDKLEKTKNRLQQEL--DDLTVDLDHQRQVASNLEKKQKKFDQLL 1499
Query: 422 TKLQKQTAKL-KEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFEC 480
+ + +A+ +E++ E + KE + + L AL E L K+ NK
Sbjct: 1500 AEEKSISARYAEERDRAEAEAREKETKALSLAR----ALEEAL---EAKEEFERQNK--- 1549
Query: 481 EVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-PYDV 539
++R ++ LE ++ + + + E R++L + ED++ + +V
Sbjct: 1550 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 1609
Query: 540 TLSKYTTTVEK---LQDEQNVLQSSMFI--INKYKGQLKDN-----------SCCPLCNR 583
+ E+ +DEQN + + I + + + +L+D + +
Sbjct: 1610 NMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1669
Query: 584 GFENESEXXXXXXXXXXXXMN-VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDT 642
E + E + + +++ +L+ A A +DEI + +EK +
Sbjct: 1670 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1729
Query: 643 EIPQLEKRIVDVDTQIK----TLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE 698
EI QL++ + + + +E +EIT S + +++ + L+ +E
Sbjct: 1730 EILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLE---EE 1786
Query: 699 IKTVTKKFEAVKEQCGDVDSEM-TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKL 757
++ E + ++ ++ TL+ A + QK R +++ K+L A ++L
Sbjct: 1787 LEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQEL 1846
Query: 758 QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALK 817
+ + K KA L + I LEE QL+ + + E LK
Sbjct: 1847 EGAVKSKFKATISALEAK-----IGQLEE---QLEQE----AKERAAANKLVRRTEKKLK 1894
Query: 818 EKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
E I + E RR+ D Y ++E A ++K L ++++ ++ E + +
Sbjct: 1895 E-IFMQVEDERRHAD------QYKEQMEKANARMKQLKRQLEEAEE-----EATRANASR 1942
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDE 937
KL + + L++++ TLK+ + + R+ + + + DD+
Sbjct: 1943 RKLQRELDDATEANEGLSREVSTLKNRLRRGGPISFS-SSRSGRRQLHLEGASLELSDDD 2001
Query: 938 LNEKLNGINKEELNEKE 954
K + +N+ + + E
Sbjct: 2002 TESKTSDVNETQPPQSE 2018
Score = 32.7 bits (71), Expect = 8.2
Identities = 44/218 (20%), Positives = 98/218 (44%), Gaps = 14/218 (6%)
Query: 892 QVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELN 951
+V TK L+ ++E+ +D ++ L +++ QT + ++ + +++L EE N
Sbjct: 878 RVFTKVKPLLQVTRQEEELQAKD-EELLKVKEKQTKVEGELEEMERKHQQL----LEEKN 932
Query: 952 EKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK----KFREKMYEL 1007
+ +T+LF + E L+ K+ L+ ++LE + ++ E+ + +K +
Sbjct: 933 ILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQA 992
Query: 1008 HVTKAIDK-DIREYA---VALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT 1063
H+ ++ D E A + L+K E +KME +++ + K + + I
Sbjct: 993 HIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAE 1052
Query: 1064 EGNLTVESERRKYDYRVVQSKNGVEI-DMRGRCSAGQK 1100
+ E E + + +++K V I D+ R +K
Sbjct: 1053 CSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEK 1090
>AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.19 protein.
Length = 820
Score = 63.7 bits (148), Expect = 4e-09
Identities = 78/379 (20%), Positives = 174/379 (45%), Gaps = 37/379 (9%)
Query: 626 ILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIK---TLNETVEEITMSLIEPEQKMTTA 682
++ + + E++ ++ TE L K + D+ + + VEE+ + E + K+ +
Sbjct: 218 LIQVATKEEELNAIR-TENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSV 276
Query: 683 KQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRN 741
+++ ++ + + ++ + ++ +A+KE+ G+V E A+Q+ K+ L+N
Sbjct: 277 EELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK------AQQLSITSKVQELQN 330
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXX 801
+K ++++N ++ + E+K K +L NT K +QD+ ES K +
Sbjct: 331 LLKGKEEQMNT----MKAVLEEKEK---DLANTGKWLQDLQEENESLKAHVQEVAQHNLK 383
Query: 802 XXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV---AFNKVKSLDAEI 858
LE+ LKEK + E+ R L E S +K ++ ++ K ++I
Sbjct: 384 EASSASQFEELEIVLKEK---ENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQI 440
Query: 859 QQHKKKNVPR--EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLD 916
+Q K++N + +E + E++K+I L ++D+LKD + Q DL
Sbjct: 441 EQLKQQNYQQASSFPPHEELLKVISEREKEI----SGLWNELDSLKDAVEHQRKKNNDLR 496
Query: 917 DNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSE 976
+ +A + + +K L +K+N +KE + E++ ++ ++ ++ S
Sbjct: 497 EKNW--EAMEALASTEKM---LQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSN 551
Query: 977 LK--KSLKGFRNELEKSLS 993
L + L GF + ++ ++
Sbjct: 552 LSYGEWLHGFEKKAKECMA 570
Score = 54.0 bits (124), Expect = 3e-06
Identities = 93/465 (20%), Positives = 200/465 (43%), Gaps = 39/465 (8%)
Query: 612 VTEDLQRASAKKDEILSMKSLNEKITTL---KDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+T+++Q AK+++ +S SL E++ + KD +I +E+ + ++ +TV+++
Sbjct: 238 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDL 297
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA-TA 727
+ ++++ + + +QE++ + K E V E D+A T
Sbjct: 298 KQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 357
Query: 728 KQV-DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
K + D +++ +L+ V+ + N + +E+ +E N K+++ + L+E
Sbjct: 358 KWLQDLQEENESLKAHVQEVAQH-NLKEASSASQFEELEIVLKEKENELKRLEAM--LKE 414
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ L S + +E LK++ + + +L++ S ++
Sbjct: 415 RESDLSSKTQLLQDVQDENKLFKSQIE-QLKQQNYQQASSFPPHEELLKVISEREKEISG 473
Query: 847 AFNKVKSL-DAEIQQHKKKNVPRE-----MEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+N++ SL DA Q KK N RE ME + L +K + +RQ + ++
Sbjct: 474 LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVEL 533
Query: 901 LKDEIAKQEVYKRDLDDNLCL--------RKAQTDI--TNWQKQDDELNEKLNGINKEEL 950
E+ K+ K + NL +KA+ + T+ ++ L KL +E
Sbjct: 534 EAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKL-----KEA 588
Query: 951 NEKESLIIKQTKLFQQ-KAECTGALSELKKSLKGFRNELEKSLS------KDIEKKFREK 1003
+E +L+ + + ++ AE G L +L++S++ N+ + + K ++ F
Sbjct: 589 DEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSS 648
Query: 1004 MYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMI--IREL 1046
EL ++ +KDI + ME + +ME + +REL
Sbjct: 649 EQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVREL 693
Score = 48.8 bits (111), Expect = 1e-04
Identities = 118/630 (18%), Positives = 252/630 (40%), Gaps = 56/630 (8%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN---LKTKEKQLIV 450
E+ Q EI+ + + + L ++ KLQ ++ K+++E+ ++ K+++L
Sbjct: 150 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 209
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
++ +T L+++ E + T N + EV +E +K I
Sbjct: 210 VEELLETGLIQVATKEEELNAIRTENS---SLTKEVQDLKAKQNDQVSFASLVEELKKVI 266
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-QNV-LQSSMFIINKY 568
E + +S E ++ K + T+ ++ L++E NV L+ + +
Sbjct: 267 HEKDGKIKSVEELLEAELLKVANKEK---TVQDLKQEIKALKEEIGNVQLEKAQQLSITS 323
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK-LEKVTEDLQRASAKKDEIL 627
K Q N +G E + + GK L+ + E+ + A E+
Sbjct: 324 KVQELQNLL-----KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEV- 377
Query: 628 SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG 687
+ +L E + ++ +LE + + + ++K L ++E E +++ Q+
Sbjct: 378 AQHNLKEASSA---SQFEELEIVLKEKENELKRLEAMLKE-------RESDLSSKTQLLQ 427
Query: 688 DMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK-ISTLRNRVKTT 746
D+ E K + E +K+Q S K + ++K IS L N + +
Sbjct: 428 DVQ------DENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSL 481
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXX 806
+ + KK L EK +A E L +T+K +QD VN ++Q Q +
Sbjct: 482 KDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVE--------- 532
Query: 807 XAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV-EVAFNKVKSLDAEIQQHKKKN 865
+ EV +K+ K V N E + K E S + ++ +HK K
Sbjct: 533 --LEAKEVL--KKLFPKVSVPS-NLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKE 587
Query: 866 VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQ 925
EM + + EK K ++ + + + +K+ ++ + K D + + +++ Q
Sbjct: 588 AD-EMHTLLQLE---CEKYKSVLAETEGILQKLQRSVEQEENKWKVKVD-ESHKTIKQMQ 642
Query: 926 TDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFR 985
+ T+ +++ + L + I E+E L ++ K +++ + ELK L +
Sbjct: 643 SSFTSSEQELERLRSENKDIENLR-REREHLEMELEKAEMERSTYVTEVRELKDLLTELQ 701
Query: 986 NELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+L+ S S+ + + + + + + + K
Sbjct: 702 KKLDDSYSEAVRQNEELNLLKAQLNETLTK 731
Score = 46.8 bits (106), Expect = 5e-04
Identities = 121/642 (18%), Positives = 239/642 (37%), Gaps = 46/642 (7%)
Query: 64 ECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKK----KTKFQTLDSFL 119
+C + ++ E L + L V K+++L R+ ++L K+ K K SF
Sbjct: 198 KCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN-SSLTKEVQDLKAKQNDQVSFA 256
Query: 120 STVDESGKT-KDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERF 178
S V+E K + + ++ L+ EL +V QE + + G E+
Sbjct: 257 SLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKA 316
Query: 179 DEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
++ K + L L K +++ +K +LE + K L+D ++N S +
Sbjct: 317 QQLSITSKVQE-LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 375
Query: 238 KIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATK 297
++A ++F LE +EK + +++ K E + ++ Q ++ ++ K
Sbjct: 376 EVAQHNLKEASSASQFEELEIVLKEK-ENELKRLEAMLKERESDLSSKTQLLQDVQDENK 434
Query: 298 TILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXX 357
++E LK + Q S E+ + + E R
Sbjct: 435 LFKSQIEQLKQQNYQQASSFPPHEELLK-VISE-REKEISGLWNELDSLKDAVEHQRKKN 492
Query: 358 XDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVE--------- 408
D+ N E + +E + E E K +
Sbjct: 493 NDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNL 552
Query: 409 QYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK---NKHKTALMELLGN 465
Y + + +K + T+ +E +++E LK ++ +L+ K+K+ L E G
Sbjct: 553 SYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGI 612
Query: 466 VPEKDFAVTI--NKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK 523
+ + +V NK++ +V LE R ++ N RR E
Sbjct: 613 LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRR-EREH 671
Query: 524 AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNR 583
E ++ KA ++ S Y T V +L+D LQ + + Y ++ N L
Sbjct: 672 LEMELEKA------EMERSTYVTEVRELKDLLTELQKKLD--DSYSEAVRQNEELNLLKA 723
Query: 584 GFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTE 643
+E V G L K + L+ +K +K+ + T +++++
Sbjct: 724 QL---NETLTKLRTEQNERQKVAGDLHKAQQSLELIQSK-----IVKAAGDT-TVIENSD 774
Query: 644 I-PQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ 684
+ P+ E + +T +LN+TV ++ L Q++T K+
Sbjct: 775 VSPETESS--EKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 814
Score = 43.6 bits (98), Expect = 0.004
Identities = 131/744 (17%), Positives = 287/744 (38%), Gaps = 48/744 (6%)
Query: 199 KDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKI---ANEKSSNEIEYNKFIL 255
K Q L + + +K++EL+D N E +K+ ANE+++ E K
Sbjct: 77 KQIKQTEDSLASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQ 136
Query: 256 LESQNQEKIDKRNEQIVETAKIAEIEN-ITEVQTNEEAENATKTILEKVESLKSDHKVQK 314
+KI EQ+ EI N + E + + A K+ ++K+++L S+ K
Sbjct: 137 SVYVKDDKIRLLEEQLQH-----EISNKMEEFKILNDQNKALKSEVQKLQTLVSEQP-NK 190
Query: 315 SQADEEEKKAQGFVDECRSGHT--QXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXX 372
++ EK Q ++ ++ + +T Q
Sbjct: 191 DVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQN 250
Query: 373 XXXXXXXXXXXHKQA--ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQ--T 428
K+ E + I+ ++ + + V E+ + +L Q+I L+++
Sbjct: 251 DQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGN 310
Query: 429 AKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFE-CEVRNEVX 487
+L++ + + K +E Q ++ + + M+ + EKD A T + + NE
Sbjct: 311 VQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESL 370
Query: 488 XXXXXXXXXXXXXXXLEAER-KHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTT 546
A + + + L E+ +EL + E + + + LS T
Sbjct: 371 KAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKER------ESDLSSKTQ 424
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXM 603
++ +QDE + +S + + + Q + +S P L E E E
Sbjct: 425 LLQDVQDENKLFKSQIEQLKQQNYQ-QASSFPPHEELLKVISEREKEISGLWNELDSLKD 483
Query: 604 NVPGKLEKVTEDLQRASAKKDEILSM--KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
V + +K DL+ + + E L+ K L +K+ Q+E ++ +K L
Sbjct: 484 AVEHQRKK-NNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKL 542
Query: 662 NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT 721
V + +L E K+ M +E+K + K + E + E
Sbjct: 543 FPKVS-VPSNLSYGEWLHGFEKKAKECMAGTSGS-EEVKVLEHKLKEADEMHTLLQLECE 600
Query: 722 LDVATAKQVD-FKQKISTLRNRVKTTQK-KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ 779
+ + + QK+ + + K K++ +K ++ + T +++EL + + +
Sbjct: 601 KYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENK 660
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLE---VALKEKI-EAKTEVVRRNRDLIE 835
DI NL ++ L+ + + L+ L++K+ ++ +E VR+N +L
Sbjct: 661 DIENLRREREHLEMELEKAEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEEL-- 718
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLT 895
+ A++ K+++ +Q++++ V ++ K Q++ + + K + D V+
Sbjct: 719 --NLLKAQLNETLTKLRT-----EQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIE 771
Query: 896 KKIDTLKDEIAKQEVYKRDLDDNL 919
+ + E +++E L+ +
Sbjct: 772 NSDVSPETESSEKETMSVSLNQTV 795
>Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein.
Length = 1356
Score = 62.9 bits (146), Expect = 7e-09
Identities = 128/630 (20%), Positives = 272/630 (43%), Gaps = 72/630 (11%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKL--QKQTAKLKEKEMIEEN--LKT 443
ENE ++ ++ + + +Q EQ + +L + K ++++ +++ ++++E+N LK
Sbjct: 525 ENE--VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 582
Query: 444 KEKQL---IVLKNKHKTALMELLGNVPEKDFAV--TINKFECEVRNEVXXXXXXXXXXXX 498
+ +Q I + EL + EKD + T + E R+ +
Sbjct: 583 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE-RDRLTSKEEELKDIQN 641
Query: 499 XXXXLEAERKHIRESLNERRS---ELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQ 555
L+AE + ++ NE+ + EL K + +Y V K E+LQ E
Sbjct: 642 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVY---------VKDDKIRLLEEQLQHEI 692
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
+ I+N LK + L + +E KL+ V E
Sbjct: 693 SNKMEEFKILNDQNKALK-SEVQKL--QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEEL 749
Query: 616 LQ----RASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS 671
L+ + + K++E+ ++++ N +T E+ L+ + D Q+ + VEE+
Sbjct: 750 LETGLIQVATKEEELNAIRTENSSLTK----EVQDLKAKQND---QV-SFASLVEELKKV 801
Query: 672 LIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
+ E + K+ + +++ ++ + + ++ + ++ +A+KE+ G+V E A+Q+
Sbjct: 802 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK------AQQL 855
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
K+ L+N +K ++++N ++ + E+K K +L NT K +QD+ ES K
Sbjct: 856 SITSKVQELQNLLKGKEEQMNT----MKAVLEEKEK---DLANTGKWLQDLQEENESLKA 908
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV---A 847
+ LE+ LKEK E+ R L E S +K ++
Sbjct: 909 HVQEVAQHNLKEASSASQFEELEIVLKEK---GNELKRLEAMLKERESDLSSKTQLLQDV 965
Query: 848 FNKVKSLDAEIQQHKKKNVPR--EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
++ K ++I+Q K++N + +E + E++K+I L ++D+LKD +
Sbjct: 966 QDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEI----SGLWNELDSLKDAV 1021
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ 965
Q DL + +A + + +K L +K+N +KE + E++ ++ ++ +
Sbjct: 1022 EHQRKKNNDLREKNW--EAMEALASTEKM---LQDKVNKTSKERQQQVEAVELEAKEVLK 1076
Query: 966 QKAECTGALSELK--KSLKGFRNELEKSLS 993
+ S L + L GF + ++ ++
Sbjct: 1077 KLFPKVSVPSNLSYGEWLHGFEKKAKECMA 1106
Score = 53.6 bits (123), Expect = 4e-06
Identities = 93/465 (20%), Positives = 200/465 (43%), Gaps = 39/465 (8%)
Query: 612 VTEDLQRASAKKDEILSMKSLNEKITTL---KDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+T+++Q AK+++ +S SL E++ + KD +I +E+ + ++ +TV+++
Sbjct: 774 LTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDL 833
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA-TA 727
+ ++++ + + +QE++ + K E V E D+A T
Sbjct: 834 KQEIKALKEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 893
Query: 728 KQV-DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
K + D +++ +L+ V+ + N + +E+ +E N K+++ + L+E
Sbjct: 894 KWLQDLQEENESLKAHVQEVAQH-NLKEASSASQFEELEIVLKEKGNELKRLEAM--LKE 950
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ L S + +E LK++ + + +L++ S ++
Sbjct: 951 RESDLSSKTQLLQDVQDENKLFKSQIE-QLKQQNYQQASSFPPHEELLKVISEREKEISG 1009
Query: 847 AFNKVKSL-DAEIQQHKKKNVPRE-----MEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+N++ SL DA Q KK N RE ME + L +K + +RQ + ++
Sbjct: 1010 LWNELDSLKDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVEL 1069
Query: 901 LKDEIAKQEVYKRDLDDNLCL--------RKAQTDI--TNWQKQDDELNEKLNGINKEEL 950
E+ K+ K + NL +KA+ + T+ ++ L KL +E
Sbjct: 1070 EAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKL-----KEA 1124
Query: 951 NEKESLIIKQTKLFQQ-KAECTGALSELKKSLKGFRNELEKSLS------KDIEKKFREK 1003
+E +L+ + + ++ AE G L +L++S++ N+ + + K ++ F
Sbjct: 1125 DEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSS 1184
Query: 1004 MYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMI--IREL 1046
EL ++ +KDI + ME + +ME + +REL
Sbjct: 1185 EQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVREL 1229
Score = 47.6 bits (108), Expect = 3e-04
Identities = 118/630 (18%), Positives = 251/630 (39%), Gaps = 56/630 (8%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN---LKTKEKQLIV 450
E+ Q EI+ + + + L ++ KLQ ++ K+++E+ ++ K+++L
Sbjct: 686 EQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKT 745
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
++ +T L+++ E + T N + EV +E +K I
Sbjct: 746 VEELLETGLIQVATKEEELNAIRTENS---SLTKEVQDLKAKQNDQVSFASLVEELKKVI 802
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-QNV-LQSSMFIINKY 568
E + +S E ++ K + T+ ++ L++E NV L+ + +
Sbjct: 803 HEKDGKIKSVEELLEAELLKVANKEK---TVQDLKQEIKALKEEIGNVQLEKAQQLSITS 859
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK-LEKVTEDLQRASAKKDEIL 627
K Q N +G E + + GK L+ + E+ + A E+
Sbjct: 860 KVQELQNLL-----KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEV- 913
Query: 628 SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG 687
+ +L E + ++ +LE + + ++K L ++E E +++ Q+
Sbjct: 914 AQHNLKEASSA---SQFEELEIVLKEKGNELKRLEAMLKE-------RESDLSSKTQLLQ 963
Query: 688 DMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK-ISTLRNRVKTT 746
D+ E K + E +K+Q S K + ++K IS L N + +
Sbjct: 964 DVQ------DENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDSL 1017
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXX 806
+ + KK L EK +A E L +T+K +QD VN ++Q Q +
Sbjct: 1018 KDAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVE--------- 1068
Query: 807 XAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV-EVAFNKVKSLDAEIQQHKKKN 865
+ EV +K+ K V N E + K E S + ++ +HK K
Sbjct: 1069 --LEAKEVL--KKLFPKVSVPS-NLSYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKE 1123
Query: 866 VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQ 925
EM + + EK K ++ + + + +K+ ++ + K D + + +++ Q
Sbjct: 1124 AD-EMHTLLQLE---CEKYKSVLAETEGILQKLQRSVEQEENKWKVKVD-ESHKTIKQMQ 1178
Query: 926 TDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFR 985
+ T+ +++ + L + I E+E L ++ K +++ + ELK L +
Sbjct: 1179 SSFTSSEQELERLRSENKDIENLR-REREHLEMELEKAEMERSTYVTEVRELKDLLTELQ 1237
Query: 986 NELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+L+ S S+ + + + + + + + K
Sbjct: 1238 KKLDDSYSEAVRQNEELNLLKAQLNETLTK 1267
Score = 45.6 bits (103), Expect = 0.001
Identities = 121/642 (18%), Positives = 240/642 (37%), Gaps = 46/642 (7%)
Query: 64 ECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKK----KTKFQTLDSFL 119
+C + ++ E L + L V K+++L R+ ++L K+ K K SF
Sbjct: 734 KCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTEN-SSLTKEVQDLKAKQNDQVSFA 792
Query: 120 STVDESGKT-KDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERF 178
S V+E K + + ++ L+ EL +V QE + + G E+
Sbjct: 793 SLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKA 852
Query: 179 DEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
++ K + L L K +++ +K +LE + K L+D ++N S +
Sbjct: 853 QQLSITSKVQE-LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQ 911
Query: 238 KIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATK 297
++A ++F LE +EK ++ +++ K E + ++ Q ++ ++ K
Sbjct: 912 EVAQHNLKEASSASQFEELEIVLKEKGNEL-KRLEAMLKERESDLSSKTQLLQDVQDENK 970
Query: 298 TILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXX 357
++E LK + Q S E+ + + E R
Sbjct: 971 LFKSQIEQLKQQNYQQASSFPPHEELLK-VISE-REKEISGLWNELDSLKDAVEHQRKKN 1028
Query: 358 XDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVE--------- 408
D+ N E + +E + E E K +
Sbjct: 1029 NDLREKNWEAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVSVPSNL 1088
Query: 409 QYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK---NKHKTALMELLGN 465
Y + + +K + T+ +E +++E LK ++ +L+ K+K+ L E G
Sbjct: 1089 SYGEWLHGFEKKAKECMAGTSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGI 1148
Query: 466 VPEKDFAVTI--NKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK 523
+ + +V NK++ +V LE R ++ N RR E
Sbjct: 1149 LQKLQRSVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRR-EREH 1207
Query: 524 AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNR 583
E ++ KA ++ S Y T V +L+D LQ + + Y ++ N L
Sbjct: 1208 LEMELEKA------EMERSTYVTEVRELKDLLTELQKKLD--DSYSEAVRQNEELNLLKA 1259
Query: 584 GFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTE 643
+E V G L K + L+ +K +K+ + T +++++
Sbjct: 1260 QL---NETLTKLRTEQNERQKVAGDLHKAQQSLELIQSK-----IVKAAGDT-TVIENSD 1310
Query: 644 I-PQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ 684
+ P+ E + +T +LN+TV ++ L Q++T K+
Sbjct: 1311 VSPETESS--EKETMSVSLNQTVTQLQQLLQAVNQQLTKEKE 1350
Score = 44.0 bits (99), Expect = 0.003
Identities = 154/846 (18%), Positives = 327/846 (38%), Gaps = 52/846 (6%)
Query: 89 AKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGV 148
AK+ +++ S L K+ Q L + + ++ K+ S + DIL E
Sbjct: 523 AKENEVQSLHSKLTDTLVSKQQLEQRLMQLMES-EQKRVNKEESLQMQVQDILEQNEALK 581
Query: 149 SKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLL 208
++ Q +S +E KV D+ + S +R + K+ + LK +
Sbjct: 582 AQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKE--EELKDI 639
Query: 209 ENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRN 268
+N +KA+ ++L+ + + E EK+ + S ++ +K LLE Q Q +I +
Sbjct: 640 QNMNFLLKAEVQKLQALANEQAAAAHELEKM---QQSVYVKDDKIRLLEEQLQHEISNKM 696
Query: 269 EQ--IVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQG 326
E+ I+ A + ++QT +E K ++E++E + K +K + EE + G
Sbjct: 697 EEFKILNDQNKALKSEVQKLQTLV-SEQPNKDVVEQMEKCIQE-KDEKLKTVEELLET-G 753
Query: 327 FVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQ 386
+ T+ +Q K
Sbjct: 754 LIQVA----TKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKI 809
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
E +E ++ EK V+ +QE+ L ++I +Q L++ + + K +E
Sbjct: 810 KSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQ-----LEKAQQLSITSKVQEL 864
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINKFE-CEVRNEVXXXXXXXXXXXXXXXXLEA 505
Q ++ + + M+ + EKD A T + + NE A
Sbjct: 865 QNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSA 924
Query: 506 ER-KHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFI 564
+ + + L E+ +EL + E + + + LS T ++ +QDE + +S +
Sbjct: 925 SQFEELEIVLKEKGNELKRLEAMLKER------ESDLSSKTQLLQDVQDENKLFKSQIEQ 978
Query: 565 INKYKGQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASA 621
+ + Q + +S P L E E E V + +K DL+ +
Sbjct: 979 LKQQNYQ-QASSFPPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKK-NNDLREKNW 1036
Query: 622 KKDEILSM--KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ E L+ K L +K+ Q+E ++ +K L V + +L E
Sbjct: 1037 EAMEALASTEKMLQDKVNKTSKERQQQVEAVELEAKEVLKKLFPKVS-VPSNLSYGEWLH 1095
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD-FKQKIST 738
K+ M +E+K + K + E + E + + + QK+
Sbjct: 1096 GFEKKAKECMAGTSGS-EEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQR 1154
Query: 739 LRNRVKTTQK-KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXX 797
+ + K K++ +K ++ + T +++EL + + +DI NL ++ L+ +
Sbjct: 1155 SVEQEENKWKVKVDESHKTIKQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEK 1214
Query: 798 XXXXXXXXXXAITPLE---VALKEKI-EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKS 853
+ L+ L++K+ ++ +E VR+N +L + A++ K+++
Sbjct: 1215 AEMERSTYVTEVRELKDLLTELQKKLDDSYSEAVRQNEEL----NLLKAQLNETLTKLRT 1270
Query: 854 LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
+Q++++ V ++ K Q++ + + K + D V+ + + E +++E
Sbjct: 1271 -----EQNERQKVAGDLHKAQQSLELIQSKIVKAAGDTTVIENSDVSPETESSEKETMSV 1325
Query: 914 DLDDNL 919
L+ +
Sbjct: 1326 SLNQTV 1331
Score = 35.9 bits (79), Expect = 0.88
Identities = 95/503 (18%), Positives = 205/503 (40%), Gaps = 56/503 (11%)
Query: 608 KLEKVTEDLQR--ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETV 665
K ++V E ++ A K++ + +++ L+ + +L K D + L E
Sbjct: 406 KFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKT 465
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
++ ++ + A Q+ + +R +E+++ +K A E ++ L
Sbjct: 466 GKLQQEEVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEA-----AQQDLQ-- 518
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLE 785
+K V + ++ +L +++ T ++L L E + K + + Q +VQDI+
Sbjct: 519 -SKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQN 577
Query: 786 ES-KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
E+ K Q+Q + + L L + I K + +++ D
Sbjct: 578 EALKAQIQQ-----FHSQIAAQTSASVLAEELHKVIAEKDKQIKQTED------------ 620
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
SL +E + K E++ IQ N L + +++ Q L + E
Sbjct: 621 --------SLASERDRLTSKE--EELKDIQNMNFLLKAEVQKL----QALANEQAAAAHE 666
Query: 905 IAK--QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK 962
+ K Q VY +D L + Q +I+N ++ LN++ N K E+ + ++L+ +Q
Sbjct: 667 LEKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQ-NKALKSEVQKLQTLVSEQPN 725
Query: 963 --LFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV-TKAIDKDIRE 1019
+ +Q +C + E + LK LE L + K+ E++ + ++ K++++
Sbjct: 726 KDVVEQMEKC---IQEKDEKLKTVEELLETGLIQVATKE--EELNAIRTENSSLTKEVQD 780
Query: 1020 YAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYR 1079
A + F +E + +I E KI ++ E+ N + K + +
Sbjct: 781 LK-AKQNDQVSF-ASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIK 838
Query: 1080 VVQSKNG-VEIDMRGRCSAGQKV 1101
++ + G V+++ + S KV
Sbjct: 839 ALKEEIGNVQLEKAQQLSITSKV 861
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 62.9 bits (146), Expect = 7e-09
Identities = 181/993 (18%), Positives = 394/993 (39%), Gaps = 99/993 (9%)
Query: 70 AKVNRSTEVLGQVKLKIVNAKDKQ----LEVTRSMKVTALAKKKTKFQTLDSFLSTVDES 125
A+V ++T +G+++ ++ A+D LE+ M + + ++ +E
Sbjct: 376 AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEK 435
Query: 126 GKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDE---IF 182
K +D+ R + + + +L V+ S + ++D + + E +++ R +
Sbjct: 436 RKVEDLQFRVEE-ESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG 494
Query: 183 DAD-------KYSDCLDRLKKIRKDYAQNL-KLLENYATTVKAKQKELEDSYKKNTSFNK 234
D D + S ++L+ R D+ + + L E++ + QKE++ Y +K
Sbjct: 495 DVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK 554
Query: 235 EEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAEN 294
E E + ++ E + I L E ++Q +E K++ + + +T E AE
Sbjct: 555 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL-GTETAEFAE- 612
Query: 295 ATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXX 354
KT +EK+ L H+++ Q ++ + R+ H +
Sbjct: 613 -LKTQIEKMR-LDYQHEIENLQNQQDSE---------RAAHAK----EMEALRAKLMKVI 657
Query: 355 XXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEE---CQQEINEDEKAVEQYE 411
+ A +S +K E E+ ++E Q + NE K ++ +
Sbjct: 658 KEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFT 717
Query: 412 QEMDELSQK---ITKLQKQTAKLK-EKEMIEENLKTKEKQ---LIVLKNKHKTALMELLG 464
++ +K + L+K +++ K E + + + L+ EKQ L + KN + +
Sbjct: 718 SQLKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITR 777
Query: 465 NVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK 523
+ ++ +T + + EV E ++ S+ E ++L +
Sbjct: 778 ELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQ 837
Query: 524 AEDKIYKAC--------GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKG----Q 571
E++ + + E+L + L++ + I K G Q
Sbjct: 838 KEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQ 897
Query: 572 L-KDNSCCPLCNRGFEN-ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
L K N L R E + + ++ K + Q A+ K +E
Sbjct: 898 LTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE--EK 955
Query: 630 KSLNEKITTLK------DTEIPQLEKRIVDVDTQIKTLNETV-EEITMSLIEPEQKMTTA 682
K L K++ L+ + +L+ R ++ KT +E + + + +L++ E K+ A
Sbjct: 956 KELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGA 1015
Query: 683 KQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNR 742
++ + + +QE++ + K+ E K D+ ++ T K+K TL +
Sbjct: 1016 REENSGL------LQELEELRKQAEKAKAAQTAEDAMQIMEQMT------KEKTETLASL 1063
Query: 743 VKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN--LEESKKQLQSDCXXXXX 800
T Q N +L TL E K EE LN K++ + N +EE +K++++
Sbjct: 1064 EDTKQTNAKLQN-ELDTLKENNLKNVEE-LNKSKELLTVENQKMEEFRKEIET-LKQAAA 1120
Query: 801 XXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSA---YIAKVEVAFNK-VKSLDA 856
A+ V L E++ + V ++ L E S + +++ +K +K D
Sbjct: 1121 QKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADE 1180
Query: 857 EIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDR------QVLTKKIDTLKDEIAKQEV 910
E + +K++ + E + +L + + ++ R + L + TL+ + K E+
Sbjct: 1181 E-KASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLEL 1239
Query: 911 YKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAEC 970
++L+ L L++ + +++ D ++ + +++ S+I+ + Q
Sbjct: 1240 KVKNLE--LQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMK 1297
Query: 971 TGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
+SE +L G ++L S D EK+ ++K
Sbjct: 1298 VEMMSE--AALNGNGDDLNNYDSDDQEKQSKKK 1328
Score = 58.0 bits (134), Expect = 2e-07
Identities = 114/606 (18%), Positives = 235/606 (38%), Gaps = 47/606 (7%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
E I+ + E N + +E+ K+T LQ+ L E ++E L EK+L
Sbjct: 755 EKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN---LSEVSQVKETL---EKELQ 808
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+LK K A E + ++ T+NK + + +EA+
Sbjct: 809 ILKEKFAEASEEAVS--VQRSMQETVNKLH-QKEEQFNMLSSDLEKLRENLADMEAK--- 862
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
RE +ER +L KA++K+ ++ + K+ DE + + + +
Sbjct: 863 FREK-DEREEQLIKAKEKLENDIAE--IMKMSGDNSSQLTKMNDELRLKERDVEELQLKL 919
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK-LEKVTEDLQRA-SAKKDEIL 627
+ +N+ + E+ + K LE+ DL++ ++
Sbjct: 920 TKANENAS--FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 977
Query: 628 SMKSLNEKITT---LKDTEIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIE---PEQKMT 680
+K+ E+ T+ K EI Q L+K ++D + ++K E + L E +K
Sbjct: 978 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAK 1037
Query: 681 TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM-TLDVATAKQVDF------- 732
A+ M ++++ +E E K+ + +E+ TL K V+
Sbjct: 1038 AAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKEL 1097
Query: 733 ----KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESK 788
QK+ R ++T ++ +++L L E+ K EEL ++ +V LEE +
Sbjct: 1098 LTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER 1157
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
L + + +L++ I + ++ +E + +
Sbjct: 1158 SVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGEN 1217
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
KSL + +Q + V E+ K++ +L E ++Q+ + + DT DE +
Sbjct: 1218 ASAKSLHSVVQTLESDKVKLEL-KVKNLELQLKENKRQLSSS----SGNTDTQADEDERA 1272
Query: 909 EVYKRDLDDNLC--LRKAQTDITNWQKQDDE--LNEKLNGINKEELNEKESLIIKQTKLF 964
+ + D +++ L++ D+ + E LN + +N + +++E K+ +LF
Sbjct: 1273 QESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLF 1332
Query: 965 QQKAEC 970
+C
Sbjct: 1333 CDICDC 1338
Score = 46.0 bits (104), Expect = 8e-04
Identities = 94/414 (22%), Positives = 182/414 (43%), Gaps = 57/414 (13%)
Query: 621 AKKDEILSMKSL--NEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
AK D++ +M EK+ L E EKR V+ D Q + E++ + + + +K
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEE---EKRKVE-DLQFRVEEESITKGDLEVATVSEK 463
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL--DVATAKQ------V 730
+ ++ D+ + +QE+ + ++ E+ K GDVD ++L ++++ ++
Sbjct: 464 -SRIMELEKDLALR---VQEVAELRRRLESNKP-AGDVDMSLSLLQEISSLQEKLEVTRT 518
Query: 731 DFKQKISTLRN----RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
D +++I++L+ R +T QK++ A + L ++ K +L + K+ D++ L +
Sbjct: 519 DHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWK 578
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITP-LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVE 845
SK L++ + + L E E KT++ + D Y ++E
Sbjct: 579 SK--LETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLD-------YQHEIE 629
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N D+E H K EME ++ KLM+ K+ + + K+D +D+
Sbjct: 630 ---NLQNQQDSERAAHAK-----EMEALRA---KLMKVIKEKENSLEAIRSKLDKAEDQ- 677
Query: 906 AKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLF 964
+ +++D L L++A+ + K+ + L K N K N L + KL
Sbjct: 678 -----HLVEMEDTLNKLQEAEIKV----KELEVLQAKCNEQTKVIDNFTSQLKATEEKLL 728
Query: 965 QQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR 1018
A A SE K +K R +LE + K I+ EK E +I ++++
Sbjct: 729 DLDA-LRKASSEGKSEMKKLRQQLE-AAEKQIKHLEIEKNAESSKASSITRELQ 780
Score = 43.2 bits (97), Expect = 0.006
Identities = 81/472 (17%), Positives = 184/472 (38%), Gaps = 34/472 (7%)
Query: 64 ECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVD 123
E V AK N T+V+ ++ ++K L++ K A ++ K++ + L L +
Sbjct: 698 ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRK--ASSEGKSEMKKLRQQLEAAE 755
Query: 124 ESGKTKDV--SSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEI 181
+ K ++ ++ + + E G + N QE+ L E +VKE ++
Sbjct: 756 KQIKHLEIEKNAESSKASSITRELQGRELKLTNL-----QEN----LSEVSQVKETLEKE 806
Query: 182 FDA--DKYSDCLDRLKKIRKDYAQNLKLLEN-------YATTVKAKQKELEDSYKKNTSF 232
+K+++ + +++ + + L ++ ++ ++ L D K
Sbjct: 807 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREK 866
Query: 233 NKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEA 292
++ EE++ K E + + + + N ++ K N+++ + E + + NE A
Sbjct: 867 DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENA 926
Query: 293 ENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXX 352
K+I + ++K++ Q++ EE+K + ++ S +
Sbjct: 927 SFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKE--LERKLSDLEKKMETSHNQCQELKAR 982
Query: 353 XXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA-VEQYE 411
+ + ++ + EN ++E ++ + EKA Q
Sbjct: 983 YERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTA 1042
Query: 412 QEMDELSQKITKLQKQT-AKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKD 470
++ ++ +++TK + +T A L++ + L + +L LK + + EL N ++
Sbjct: 1043 EDAMQIMEQMTKEKTETLASLEDTKQTNAKL---QNELDTLKENNLKNVEEL--NKSKEL 1097
Query: 471 FAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V K E E R E+ L+ E + E L R E+T
Sbjct: 1098 LTVENQKME-EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVT 1148
Score = 41.1 bits (92), Expect = 0.023
Identities = 81/417 (19%), Positives = 173/417 (41%), Gaps = 37/417 (8%)
Query: 618 RASAKKDEILSMKSLNEKITTLKDTEIPQLE---KRIVDVDTQIKTLNETVEEITMSLIE 674
R + EI ++ + EK++ ++ +LE K DV K+ ET +E
Sbjct: 534 REETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAME 593
Query: 675 PEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFE-AVKEQCGDVDSEMTLDVATAKQVDFK 733
E K++ +K + + +I+ + ++ ++ DSE A AK+++
Sbjct: 594 -ELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERA---AHAKEMEAL 649
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLN----TQKKVQDIVNLEESKK 789
+ + L +K + L A KL ++ E+ LN + KV+++ L+
Sbjct: 650 R--AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCN 707
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
+ + L+ K E K+E+ ++ R +EA I +E+ N
Sbjct: 708 EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEM-KKLRQQLEAAEKQIKHLEIEKN 766
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQE 909
S K ++ RE++ + L E ++ ++ L K++ LK++ A+
Sbjct: 767 AESS--------KASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEAS 818
Query: 910 VYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
++ + ++++ + N Q + E+ N ++ + +E+L + K F++K E
Sbjct: 819 ------EEAVSVQRSMQETVNKLHQKE---EQFNMLSSDLEKLRENLADMEAK-FREKDE 868
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
L + K+ L+ E+ K +S D + + EL + ++D+ E + L K
Sbjct: 869 REEQLIKAKEKLENDIAEIMK-MSGDNSSQLTKMNDELRLK---ERDVEELQLKLTK 921
Score = 33.5 bits (73), Expect = 4.7
Identities = 52/268 (19%), Positives = 113/268 (42%), Gaps = 17/268 (6%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK-VTALAKKKTKFQTLDSFLSTVDESG 126
H+ + + L + K+ A+++ + + ++ + A+K QT + + +++
Sbjct: 994 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQM- 1052
Query: 127 KTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFD-EIFDAD 185
TK+ + A L E+ + A L + + +E++ ++E K KE E +
Sbjct: 1053 -TKEKTETLASL-----EDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKME 1106
Query: 186 KYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
++ ++ LK+ +Q L L+ + + D + +E + N+
Sbjct: 1107 EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLE 1166
Query: 246 NEIEYNKFILLESQNQEKIDKRNE--QIVETAKIAEIENITEVQTNEEAENAT-KTILEK 302
+ +KFI + + + K + T K AE+E + T ENA+ K++
Sbjct: 1167 MKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1226
Query: 303 VESLKSDH-----KVQKSQADEEEKKAQ 325
V++L+SD KV+ + +E K Q
Sbjct: 1227 VQTLESDKVKLELKVKNLELQLKENKRQ 1254
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 62.9 bits (146), Expect = 7e-09
Identities = 171/906 (18%), Positives = 361/906 (39%), Gaps = 94/906 (10%)
Query: 101 KVTALAKKKTKF-QTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFC 159
KV L K KTK Q +D ++++ K + DL+ + G K S +
Sbjct: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLR------MDLERAKRKLEGDLKLAQESTM-- 1070
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQ 219
E+ LDE K K+ F+ K D +++K + +E ++A++
Sbjct: 1071 DMENDKQQLDE-KLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAER 1129
Query: 220 KELEDSYKKNTSFNKEEEKI------ANEKSSNEIEYNKFILLESQ----NQEKIDKRNE 269
+ K+ + ++E E+I A +S ++E NK E Q + E+ ++E
Sbjct: 1130 ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHE 1189
Query: 270 QIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQK---SQADEEEKKAQG 326
+V + +++ E+ E+ +N + + +K+E KS+ K++ S E KA+G
Sbjct: 1190 AMVAALRKKHADSMAEL--GEQIDNLQR-VKQKLEKEKSELKMETDDLSSNAEAISKAKG 1246
Query: 327 FVDE-CRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXX--XX 383
+++ CRS Q ++
Sbjct: 1247 HLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSR 1306
Query: 384 HKQAENELNIEECQQEINEDEKAV------------------EQYEQEMD---ELSQKIT 422
KQA + IEE + ++ E+ KA EQYE+E + EL + ++
Sbjct: 1307 SKQASTQ-QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1365
Query: 423 KLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDF-AVTINKFECE 481
K + A+ + K + +T+E L K K L E +V + ++ K +
Sbjct: 1366 KANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQR 1423
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE--RRSELTKAEDKIYKACGTQPYDV 539
++NEV L+ ++++ + L+E ++ E T+AE + + ++
Sbjct: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQK-ESRSLST 1482
Query: 540 TLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXX 599
L K E+ D+ L+ + + + L + G + E
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRAHKNLQQEISDLTEQIA-----EGGKQIHELEKIKKQVE 1537
Query: 600 XXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD 655
+ LE+ L+ K + E+ +KS ++ KD EI QL++ V
Sbjct: 1538 QEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRV- 1596
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCG 714
++T+ T++ S + K++ GD+ ++ + + + + G
Sbjct: 1597 --VETMQSTLDAEIRSR---NDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQG 1651
Query: 715 DV-DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLN 773
+ ++++ LD A Q D K++++ + R Q ++ L+ + A++ELL+
Sbjct: 1652 ILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLD 1711
Query: 774 TQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI---EAKTEV 826
++VQ + +L +KK+L++D E K+ I E
Sbjct: 1712 ASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEE 1771
Query: 827 VRRNRDLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQK 885
+++ +D SA++ +++ + VK L + + ++ + ++IQ+ ++ E +
Sbjct: 1772 LKKEQDT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEG 1827
Query: 886 QIMTDRQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCLR------KAQTDITNWQKQDDE 937
++ +++ + + L+ D K+ Y+ + D LR K Q + ++++Q +E
Sbjct: 1828 EVENEQKRNAEAVKGLRKHDRRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEE 1887
Query: 938 LNEKLN 943
E+ N
Sbjct: 1888 AEEQSN 1893
Score = 50.8 bits (116), Expect = 3e-05
Identities = 111/615 (18%), Positives = 262/615 (42%), Gaps = 68/615 (11%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
+N+L ++ Q E + A E+ EQ + Q K+++ T + +E+E I L K+++
Sbjct: 887 KNDLQLQ-VQSEADSLADAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRK 945
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAE 506
L + EL ++ + + + + K + N+V L E
Sbjct: 946 L-------EDECSELKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKE 998
Query: 507 RKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIIN 566
+K ++E+ + +L EDK+ L+K T +E+ D+ L+ S+
Sbjct: 999 KKALQETHQQTLDDLQAEEDKVN----------ILTKAKTKLEQQVDD---LEGSLEQEK 1045
Query: 567 KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI 626
K + L+ R E + + M++ +++ E L++ K+ EI
Sbjct: 1046 KLRMDLER------AKRKLEGDLKLAQEST------MDMENDKQQLDEKLEK---KEFEI 1090
Query: 627 LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIH 686
++ S KI + EI QL+K+I ++ +I+ L E +E S + E++ + +
Sbjct: 1091 SNLIS---KIEDEQAVEI-QLQKKIKELQARIEELGEEIEAERASRAKAEKQRS---DLS 1143
Query: 687 GDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTT 746
++ + ++E T + ++ ++ D+ A + + ++ LR + +
Sbjct: 1144 RELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA-TLQHEAMVAALRKKHADS 1202
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+L LQ + +K K K EL + T + + ++K L+ C
Sbjct: 1203 MAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKMC-------RSL 1255
Query: 806 XXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKN 865
++ L+ +E+ ++ + L Y +++ + +L +++ + K+ +
Sbjct: 1256 EDQVSGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLD----EQDALVSQLSRSKQAS 1311
Query: 866 VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQ 925
+++E+++ ++ + + + Q D L+++ +++ K +L L KA
Sbjct: 1312 T-QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAEL--QRALSKAN 1368
Query: 926 TDITNWQ-KQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA-LSELKKSLKG 983
+++ W+ K + + ++ EEL E + + ++ + ++ E A + L+K+ +
Sbjct: 1369 SEVAQWRTKYETDAIQR-----TEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQR 1423
Query: 984 FRNELEKSLSKDIEK 998
+NE+E L D+E+
Sbjct: 1424 LQNEVE-DLMLDVER 1437
Score = 48.8 bits (111), Expect = 1e-04
Identities = 40/164 (24%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDI-TNWQKQ 934
K+ K T++++ T K KDE+AK E +++L++ + L K + D+ Q +
Sbjct: 838 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 897
Query: 935 DDEL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
D L E+ + K ++ + E+ I + T+ +++ E L+ K+ L+ +EL+K
Sbjct: 898 ADSLADAEERCEQLIKNKI-QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKD 956
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + + H T+ K++ E LD+ + + +EK
Sbjct: 957 ID-DLELTLAKVEKQKHATENKVKNLTEEMAGLDETIAKLSKEK 999
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 62.9 bits (146), Expect = 7e-09
Identities = 115/637 (18%), Positives = 263/637 (41%), Gaps = 50/637 (7%)
Query: 384 HKQAEN---ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-K 432
H QAE + NI+E ++++ E+E A ++ + E K+ KL++ Q KL K
Sbjct: 219 HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAK 278
Query: 433 EKEMIEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEV 482
EK+++E+ + + K K L LKNKH+ + +L + ++ K E+
Sbjct: 279 EKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE------KQRQEL 332
Query: 483 RNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS 542
L+A+ ++ L ++ EL A ++ + + ++ L
Sbjct: 333 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK--NMALK 390
Query: 543 KYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD-NSCCPLCNRGFENESEXXXXXXXXXXX 601
K ++ + Q L+S NK + Q +D E+ +
Sbjct: 391 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 450
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
L+K E + A + +I M+ + + ++ Q ++ +++ +TL
Sbjct: 451 REQEVNILKKTLE--EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 508
Query: 662 ----NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTV-TKKFEAVKEQCGDV 716
E E+ + L K++ + L E + V T+ + V + ++
Sbjct: 509 ENERGELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 568
Query: 717 DSEM-TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
D+ L + +K + S L ++++ TQ+ L N++ +L K + ++E + +
Sbjct: 569 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 628
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
+++++ EE+K L+ + L+ E K ++ +DL
Sbjct: 629 EQLEE--EEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL---QKDLEG 683
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQK---QIMTDRQ 892
+ KV A++K++ +QQ + ++ +++ +++ L +KQK Q++ + +
Sbjct: 684 LSQRHEEKV-AAYDKLEKTKTRLQQ-ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 741
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
++ K +D A+ E +++ L L +A + + + + LN++ ++ ++
Sbjct: 742 TISAKYAEERDR-AEAEAREKE-TKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS 799
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
K+ + +L + K + E+K L+ +EL+
Sbjct: 800 KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 836
Score = 61.3 bits (142), Expect = 2e-08
Identities = 153/747 (20%), Positives = 306/747 (40%), Gaps = 85/747 (11%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
E L EE Q++ E EK + E + +LS +I +LQ Q A+LK + L KE++
Sbjct: 319 EERLRREEKQRQ--ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ------LAKKEEE 370
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
L + AL + +K+ A + K E+ +++ E ++
Sbjct: 371 L-------QAALARVEEEAAQKNMA--LKKIR-ELESQISELQEDLESERASRNKAEKQK 420
Query: 508 KHIRESLNERRSELTKAEDKI---YKACGTQPYDVTLSKYTTTVEKLQDE---QNVLQSS 561
+ + E L ++EL D + + +V + K T E E Q + Q
Sbjct: 421 RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH 480
Query: 562 MFIINKYKGQLKDNSCCPL----CNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + QL+ + ENE E + K +KV L
Sbjct: 481 SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVEAQL 540
Query: 617 QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
Q K +E E++ T ++ +L+ + +V + + ++T E
Sbjct: 541 QELQVKFNE-------GERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALE 593
Query: 677 QKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI 736
++ +++ L ++ +++ K + V+++ ++ + AK + +++I
Sbjct: 594 SQLQDTQEL------LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKH-NLEKQI 646
Query: 737 STLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV----NLEESKKQLQ 792
+TL +V +KK+ L+T E K K +++L ++ ++ V LE++K +LQ
Sbjct: 647 ATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQ 706
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKE----KIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
+ + LE K+ E KT + + A + K A
Sbjct: 707 QELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKAL 766
Query: 849 NKVKSLDAEIQQHKK-----KNVPREMEKIQEANDKL------MEKQKQIMTDR-QVLTK 896
+ ++L+ ++Q + K EME + + D + +EK K+ + + + +
Sbjct: 767 SLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKT 826
Query: 897 KIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
+++ L+DE+ E K L+ NL KAQ + + Q +D++ EK + + ++ E E+
Sbjct: 827 QLEELEDELQATEDAKLRLEVNLQAMKAQFE-RDLQGRDEQSEEKKKQLVR-QVREMEAE 884
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGF----------RNELEKSLSKDIEKKFREKMYE 1006
+ + K Q++ A +L+ LK R+E K L K ++ + ++ M E
Sbjct: 885 LEDERK---QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK-LQAQMKDCMRE 940
Query: 1007 LHVTKAIDKDIREYAVALDKCL--MEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT- 1063
L T+A ++I A +K L ME +++ R+ + D EI
Sbjct: 941 LDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANS 1000
Query: 1064 --EGNLTVESERRKYDYRVVQSKNGVE 1088
+G L +E E+R+ + R+ Q + +E
Sbjct: 1001 SGKGALALE-EKRRLEARIAQLEEELE 1026
Score = 52.8 bits (121), Expect = 7e-06
Identities = 120/657 (18%), Positives = 272/657 (41%), Gaps = 47/657 (7%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN 453
+E ++ ++ E VE+ E+ L + K+Q+ +L E+++ EE ++ QL +
Sbjct: 197 QELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQEL-EEQLEEEESARQKLQLEKVTT 255
Query: 454 KHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ K +E + + + C++ E E + K + +
Sbjct: 256 EAKLKKLE--------EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 307
Query: 514 LNERRSELTKAEDKIYK-ACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQL 572
N+ + +T E+++ + Q + T K L D+ LQ+ I + K QL
Sbjct: 308 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ---IAELKMQL 364
Query: 573 KDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL--QRASAKKDEILSMK 630
E + ++ ++ EDL +RAS K E +
Sbjct: 365 AKKE--EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAE-KQKR 421
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMP 690
L E++ LK TE+ ++++ E I +E E K T QI
Sbjct: 422 DLGEELEALK-TELEDTLDSTA-AQQELRSKREQEVNILKKTLEEEAK-THEAQI---QE 475
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAKQVDFKQKISTLRNRVKTTQKK 749
M ++ Q ++ + ++ E K +++ ++ TL+ + + + + + +KK
Sbjct: 476 MRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSEHKRKK 535
Query: 750 LNAHNKKLQTLYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXA 808
+ A ++LQ + + + + EL + K+Q ++ N+ Q S
Sbjct: 536 VEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQ 595
Query: 809 ITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK-SLDAEIQQ-HKK-KN 865
+ + L+E+ K + + + + + +++ ++E + K +L+ +I H + +
Sbjct: 596 LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVAD 655
Query: 866 VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKID---TLKDEIAKQEV-YKRDLDDNLC- 920
+ ++ME + E ++++ D + L+++ + D++ K + +++LDD L
Sbjct: 656 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVD 715
Query: 921 ---LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLII----KQTK---LFQQKAEC 970
R++ ++ QK+ D+L + I+ + E++ K+TK L + E
Sbjct: 716 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 775
Query: 971 TGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIREYAVALDK 1026
+EL++ K FR E+E +S + + ++EL +K A+++ + E L++
Sbjct: 776 MEQKAELERLNKQFRTEMEDLMSS--KDDVGKSVHELEKSKRALEQQVEEMKTQLEE 830
Score = 52.8 bits (121), Expect = 7e-06
Identities = 138/850 (16%), Positives = 340/850 (40%), Gaps = 42/850 (4%)
Query: 126 GKTKDVSSRCADLDILMHE---ELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIF 182
G + D+S + A+L + E +L + L + + +E+++ KK++E +I
Sbjct: 341 GDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQIS 400
Query: 183 DA--DKYSDCLDRLK--KIRKDYAQNLKLLEN-YATTVKAKQKELEDSYKKNTSFNKEEE 237
+ D S+ R K K ++D + L+ L+ T+ + + E K+ N ++
Sbjct: 401 ELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKK 460
Query: 238 KIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKI-AEIENITEVQTNEEAENAT 296
+ E ++E + + + ++ + +++ EQ+ +T ++ A +E + NE E A
Sbjct: 461 TLEEEAKTHEAQIQE---MRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELAN 517
Query: 297 KTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXX 356
+ + S+HK +K +A +E + + F + R
Sbjct: 518 EVKVLLQGGRDSEHKRKKVEAQLQELQVK-FNEGERVRTELADKVTKLQVELDNVTGLLS 576
Query: 357 XXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAV-EQYEQEMD 415
D S+ + ++ +L++ +++ +++ + EQ E+E +
Sbjct: 577 QSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 636
Query: 416 E----LSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDF 471
E L ++I L Q A +K+K +E+++ E V K K + L L EK
Sbjct: 637 EAKHNLEKQIATLHAQVADMKKK--MEDSVGCLETAEEV-KRKLQKDLEGLSQRHEEKVA 693
Query: 472 AV-TINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK-AEDKIY 529
A + K + ++ E+ LE ++K + L E ++ K AE++
Sbjct: 694 AYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDR 753
Query: 530 KACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENES 589
+ + +E+ +++ L+ + +++ +++D +E
Sbjct: 754 AEAEAREKETKALSLARALEEAMEQKAELER---LNKQFRTEMEDLMSSKDDVGKSVHEL 810
Query: 590 EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKK----DEILSMKSLNEKITTLKDTEIP 645
E M +LE++ ++LQ K + +MK+ E+ +D +
Sbjct: 811 EKSKRALEQQVEEMKT--QLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSE 868
Query: 646 QLEKRIV-DVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTK 704
+ +K++V V L + ++ +M++ ++ K + + ++ E +
Sbjct: 869 EKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLR 928
Query: 705 KFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYE 762
K +A + C D+ + + A+ + ++K+ ++ + Q++L A + + +
Sbjct: 929 KLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQ 988
Query: 763 KKTKAKEELLNTQKK----VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
++ + +E+ N+ K +++ LE QL+ + + + + +
Sbjct: 989 ERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQI-D 1047
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN-KVKSLDAEIQQHKKKNVPREMEKIQEAN 877
+I A + R + E + + K++ ++ ++ K ++ KI +
Sbjct: 1048 QINADLNLERGHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLE 1107
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDD 936
++L + K+ + + + LKD + + + +R+ + KA T + ++Q +
Sbjct: 1108 EQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLE 1167
Query: 937 ELNEKLNGIN 946
E E+ N
Sbjct: 1168 EAEEEAQRAN 1177
Score = 41.5 bits (93), Expect = 0.018
Identities = 118/657 (17%), Positives = 239/657 (36%), Gaps = 61/657 (9%)
Query: 169 DEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKK 228
+EG++V+ ADK + L + +Q+ A + +L+D+ +
Sbjct: 548 NEGERVRTEL-----ADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQEL 602
Query: 229 NTSFNKEEEKIANEKSSNEIEYNKFI-LLESQNQEKIDKRNEQIVET-AKIAEIENITE- 285
N+++ ++ + E E N F LE + +E +QI A++A+++ E
Sbjct: 603 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLHAQVADMKKKMED 662
Query: 286 -VQTNEEAENATKTILEKVESLKSDH--------KVQKSQADEEEKKAQGFVD------- 329
V E AE + + + +E L H K++K++ +++ VD
Sbjct: 663 SVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQS 722
Query: 330 ECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAEN 389
C Q D A ++AE
Sbjct: 723 ACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAEL 782
Query: 390 E-LN------IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLK 442
E LN +E+ ++ K+V + E+ L Q++ +++ Q +L+++ E+ K
Sbjct: 783 ERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAK 842
Query: 443 TK-EKQLIVLKNKHKTALM--ELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
+ E L +K + + L + +K + + E E+ +E
Sbjct: 843 LRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKL 902
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIY---KACGTQPYDVTLSKYTTTVEKLQDEQN 556
L+ HI +S N+ R E K K+ K C + D S+ + ++E+
Sbjct: 903 EMDLKDLEAHI-DSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKK 961
Query: 557 V---------LQSSMFIINKYKGQL---KDNSCCPLCNRG------FENESEXXXXXXXX 598
+ LQ + + K Q +D + N E +
Sbjct: 962 LKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQL 1021
Query: 599 XXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQI 658
G E + + L++A+ + D+I + +L + QLE++ ++ ++
Sbjct: 1022 EEELEEEQGNTELINDRLKKANLQIDQINADLNLERGHAQKNENARQQLERQNKELKVKL 1081
Query: 659 KTLNETVE-EITMSLIEPEQKMT-TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDV 716
+ + TV+ + S+ E K+ +Q+ + ++++ KK + V Q D
Sbjct: 1082 QEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDE 1141
Query: 717 --DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL 771
++E D A KQ L + Q + NA +KLQ E T+ + +
Sbjct: 1142 RRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQ-RANASRRKLQRELEDATETADAM 1197
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 62.5 bits (145), Expect = 9e-09
Identities = 138/727 (18%), Positives = 285/727 (39%), Gaps = 62/727 (8%)
Query: 188 SDCLDRLKKIRKDYAQNL-KLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S ++L+ R D+ + + L E++ + QKE++ Y +KE E + ++
Sbjct: 293 SSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHA 352
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E + I L E ++Q +E K++ + + +T E AE KT +EK+ L
Sbjct: 353 NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL-GTETAEFAE--LKTQIEKMR-L 408
Query: 307 KSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQS 366
H+++ Q ++ ++A E + + D
Sbjct: 409 DYQHEIENLQNQQDSERA-AHAKEMEA--LRAKLMKVIKEKENSLEAIRSKLDKAEDQHL 465
Query: 367 XXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK 426
K AE Q+ + E + Q E++ + LS + KL++
Sbjct: 466 VEMEDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRE 525
Query: 427 ----QTAKLKEKEMIEENL-KTKEK------QLIVLKNKHKTALMELLGNVPEKDFAVTI 475
AK +EK+ EE L K KEK +++ + + + L ++ + K+ V
Sbjct: 526 NLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEE 585
Query: 476 NKFECEVRNE---VXXXXXXXXXXXXXXXXLEAERKHIRE--SLNERRSELTKAEDKIYK 530
+ + NE EA +KH E L + S+L K + +
Sbjct: 586 LQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHN 645
Query: 531 ACGTQPYDVTLSKYTTTVEKLQDE--QNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENE 588
C Q + T+ + +E QN+ ++ + +K KG ++NS +
Sbjct: 646 QC--QELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQ 703
Query: 589 SEXXXXXXXXXXXXMNVPGKLEKVT------EDLQRASAK-KDEILSMKSLN----EKIT 637
+E + ++ T ED ++ +AK ++E+ ++K N E++
Sbjct: 704 AEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELN 763
Query: 638 TLKD-------------TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ 684
K+ EI L++ Q+ L E ++ L ++T+ ++
Sbjct: 764 KSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQK 823
Query: 685 IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLRNRV 743
+ + +L+ + E+K KF +K+ + S + ++ + +A + ++ LRN V
Sbjct: 824 LEEERSVLNNQLLEMKKRESKF--IKDADEEKASLQKSISITSALLTEKDAELEKLRNEV 881
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXX 802
T + NA K L ++ + K +L + KV+++ + L+E+K+QL S
Sbjct: 882 -TVLRGENASAKSLHSVVQTLESDKVKL---ELKVKNLELQLKENKRQLSSSSGNTDTQA 937
Query: 803 XXXXXAITPLEVALKEKIEAKTEVVRRNRDL-IEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
A ++ + ++ R+N+DL ++ A + + + + D++ Q+
Sbjct: 938 DEDERAQESQQM-IDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEK 996
Query: 862 KKKNVPR 868
+ K PR
Sbjct: 997 QSKKKPR 1003
Score = 51.2 bits (117), Expect = 2e-05
Identities = 111/629 (17%), Positives = 242/629 (38%), Gaps = 52/629 (8%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE--KEMIEENLKTKEKQLIVL 451
E Q+EI A E+ +E + L K+ K+ + + K +E + + ++ + L
Sbjct: 322 ETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEEL 381
Query: 452 KNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX-LEAERKHI 510
K L E I K + ++E+ +EA R +
Sbjct: 382 KVSFSKGLGTETAEFAE--LKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKL 439
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKG 570
+ + E+ + L K+ KA D L + T+ KLQ+ + ++ F +
Sbjct: 440 MKVIKEKENSLEAIRSKLDKA-----EDQHLVEMEDTLNKLQEAE--IKKEKFAEASEEA 492
Query: 571 QLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTE------DLQRASAKKD 624
S N+ + E + N+ K E L +A K +
Sbjct: 493 VSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLE 552
Query: 625 ----EILSMKSLNEKITT-------LKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLI 673
EI+ M N T LK+ ++ +L+ ++ + L +++E++T+
Sbjct: 553 NDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAE 612
Query: 674 EPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFK 733
+ +Q+ AK+ + L+R + +++ KK E QC ++ + + K +
Sbjct: 613 QSQQE--AAKKHEEEKKELERKLSDLE---KKMETSHNQCQELKARYERATSETK-TKHE 666
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLYE--KKTKAKEELLNTQKKVQDIVNLEESKKQL 791
+ + L+ + T+ KL ++ L + ++ + + E + +D + + E +
Sbjct: 667 EILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKE 726
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+++ + LKE E + ++++L+ + + + +
Sbjct: 727 KTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETL 786
Query: 852 KSLDAEIQQH----KKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAK 907
K A+ Q +++NV + E++ + D++ QK + +R VL ++ +K +K
Sbjct: 787 KQAAAQKSQQLSALQEENV-KLAEELGRSRDEVTSHQK-LEEERSVLNNQLLEMKKRESK 844
Query: 908 QEVYKRDLDDNLCLRKAQTDITN--WQKQDDELNEKLNGI---NKEELNEKESLIIKQTK 962
+ +D D+ + IT+ ++D EL + N + E + K + QT
Sbjct: 845 ---FIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQT- 900
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEKS 991
L K + + L+ LK + +L S
Sbjct: 901 LESDKVKLELKVKNLELQLKENKRQLSSS 929
Score = 50.8 bits (116), Expect = 3e-05
Identities = 84/431 (19%), Positives = 196/431 (45%), Gaps = 38/431 (8%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
++ EDLQ ++E ++ L E T L+ I +LE+ ++ T+ L +E+
Sbjct: 186 KRKVEDLQ--FRVEEESITKGDL-ETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTR 242
Query: 670 MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL--DVATA 727
++ + + ++ ++ D+ + +QE+ + ++ E+ K GDVD ++L ++++
Sbjct: 243 VATVSEKSRIM---ELEKDLALR---VQEVAELRRRLESNKP-AGDVDMSLSLLQEISSL 295
Query: 728 KQ------VDFKQKISTLRN----RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
++ D +++I++L+ R +T QK++ A + L ++ K +L + K+
Sbjct: 296 QEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKE 355
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITP-LEVALKEKIEAKTEVVRRNRDLIEA 836
D++ L +SK L++ + + L E E KT++ + D +
Sbjct: 356 NSDVIALWKSK--LETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLD-YQH 412
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEA-NDKLMEKQKQIMTDRQVLT 895
+ + + + + E + K V +E E EA KL + + Q + + +
Sbjct: 413 EIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVE---ME 469
Query: 896 KKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
++ L++ K+E + ++ + ++++ + N Q + E+ N ++ + +E+
Sbjct: 470 DTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKE---EQFNMLSSDLEKLREN 526
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L + K F++K E L + K+ L+ E+ K +S D + + EL + ++
Sbjct: 527 LADMEAK-FREKDEREEQLIKAKEKLENDIAEIMK-MSGDNSSQLTKMNDELRLK---ER 581
Query: 1016 DIREYAVALDK 1026
D+ E + L K
Sbjct: 582 DVEELQLKLTK 592
Score = 50.4 bits (115), Expect = 4e-05
Identities = 139/809 (17%), Positives = 299/809 (36%), Gaps = 63/809 (7%)
Query: 219 QKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIA 278
Q +LE + K + EK +K E+E + + S+ ++ + + ++A
Sbjct: 209 QTKLEHARIKELEQSLLFEKTKADKLQRELEDTR-VATVSEKSRIMELEKDLALRVQEVA 267
Query: 279 EIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQX 338
E+ E + + ++L+++ SL+ +V ++ E + H +
Sbjct: 268 ELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKE 327
Query: 339 XXXXXXXXXXXXXXXXXXXXDITSAN-QSXXXXXXXXXXXXXXXXXHKQAENELNIEECQ 397
+ AN ++ H+QA EL + +
Sbjct: 328 IKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSK 387
Query: 398 ---QEINEDEKAVEQYEQEMDELSQKITKLQKQ-----TAKLKEKEMIEENL----KTKE 445
E E + Q E+ + +I LQ Q A KE E + L K KE
Sbjct: 388 GLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKE 447
Query: 446 KQLIVLKNK-------HKTALMELLGNVPE----KDFAVTINKFECEVRNEVXXXXXXXX 494
L +++K H + + L + E K+ ++ V+ +
Sbjct: 448 NSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLH 507
Query: 495 XXXXXXXXLEAERKHIRESLNERRS---ELTKAEDKIYKACGTQPYDVT-LSKYT----T 546
L ++ + +RE+L + + E + E+++ KA D+ + K + +
Sbjct: 508 QKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSS 567
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
+ K+ DE + + + + + +N+ + E+ +
Sbjct: 568 QLTKMNDELRLKERDVEELQLKLTKANENAS--FLQKSIEDMTVKAEQSQQEAAKKHEEE 625
Query: 607 GK-LEKVTEDLQRA-SAKKDEILSMKSLNEKITT---LKDTEIPQ-LEKRIVDVDTQIKT 660
K LE+ DL++ ++ +K+ E+ T+ K EI Q L+K ++D + ++K
Sbjct: 626 KKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKG 685
Query: 661 LNETVEEITMSLIE---PEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
E + L E +K A+ M ++++ +E E K+ +
Sbjct: 686 AREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ 745
Query: 718 SEM-TLDVATAKQVDF-----------KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
+E+ TL K V+ QK+ R ++T ++ +++L L E+
Sbjct: 746 NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENV 805
Query: 766 KAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTE 825
K EEL ++ +V LEE + L + + +L++ I +
Sbjct: 806 KLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSA 865
Query: 826 VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQK 885
++ +E + + KSL + +Q + V E+ K++ +L E ++
Sbjct: 866 LLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLEL-KVKNLELQLKENKR 924
Query: 886 QIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC--LRKAQTDITNWQKQDDE--LNEK 941
Q+ + + D +DE A++ D +++ L++ D+ + E LN
Sbjct: 925 QLSSSSGNTDTQAD--EDERAQESQQMIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGN 982
Query: 942 LNGINKEELNEKESLIIKQTKLFQQKAEC 970
+ +N + +++E K+ +LF +C
Sbjct: 983 GDDLNNYDSDDQEKQSKKKPRLFCDICDC 1011
Score = 43.2 bits (97), Expect = 0.006
Identities = 128/725 (17%), Positives = 283/725 (39%), Gaps = 65/725 (8%)
Query: 81 QVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKD-VSSRCADLD 139
Q KL++ D Q E+T S+K A+++T + + + + ++ K + + S+ +
Sbjct: 296 QEKLEVTRT-DHQREIT-SLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHAN 353
Query: 140 ILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRK 199
+ + + K+ L + + HQ+ E KV + ++++ +++K+R
Sbjct: 354 KENSDVIALWKSKLETAIASHQQAM-----EELKVSFSKGLGTETAEFAELKTQIEKMRL 408
Query: 200 DYAQNLKLLENYATTVKAKQ-KELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLES 258
DY ++ L+N + +A KE+E K KE+E N +E + L ++
Sbjct: 409 DYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKE--------NSLEAIRSKLDKA 460
Query: 259 QNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQAD 318
++Q ++ E + + AEI+ + +EEA + +++ E V L + +
Sbjct: 461 EDQHLVEM--EDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSS 518
Query: 319 EEEKKAQGFVD-ECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXX 377
+ EK + D E + ++ N S
Sbjct: 519 DLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRL 578
Query: 378 XXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL--KEKE 435
E ++EE Q ++ + + ++ +++++ K + Q++ AK +EK+
Sbjct: 579 -----------KERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKK 627
Query: 436 MIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXX 495
+E L EK++ N+ EL E+ + T K E ++N
Sbjct: 628 ELERKLSDLEKKMETSHNQ----CQELKARY-ERATSETKTKHEEILQN----LQKTLLD 678
Query: 496 XXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQ 555
E + + L E R + KA+ Q + + T T+ L+D +
Sbjct: 679 TEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTK 738
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
Q++ + N+ LK+N+ +N E + + K E
Sbjct: 739 ---QTNAKLQNEL-DTLKENN--------LKNVEELNKSKELLTVENQKME-EFRKEIET 785
Query: 616 LQRASAKKDEILSM-----KSLNEKITTLKD--TEIPQLEKRIVDVDTQIKTLNETVEEI 668
L++A+A+K + LS L E++ +D T +LE+ ++ Q+ + + +
Sbjct: 786 LKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKF 845
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATA 727
E+K + K I +L E++ + + ++ + S + +
Sbjct: 846 IKD--ADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLES 903
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+V + K+ L ++K +++L++ + T ++ +A+E IV+L+
Sbjct: 904 DKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQQMIDFLNSVIVDLQRK 963
Query: 788 KKQLQ 792
+ L+
Sbjct: 964 NQDLK 968
Score = 33.5 bits (73), Expect = 4.7
Identities = 52/268 (19%), Positives = 113/268 (42%), Gaps = 17/268 (6%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK-VTALAKKKTKFQTLDSFLSTVDESG 126
H+ + + L + K+ A+++ + + ++ + A+K QT + + +++
Sbjct: 665 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQM- 723
Query: 127 KTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFD-EIFDAD 185
TK+ + A L E+ + A L + + +E++ ++E K KE E +
Sbjct: 724 -TKEKTETLASL-----EDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKME 777
Query: 186 KYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
++ ++ LK+ +Q L L+ + + D + +E + N+
Sbjct: 778 EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLE 837
Query: 246 NEIEYNKFILLESQNQEKIDKRNE--QIVETAKIAEIENITEVQTNEEAENAT-KTILEK 302
+ +KFI + + + K + T K AE+E + T ENA+ K++
Sbjct: 838 MKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 897
Query: 303 VESLKSDH-----KVQKSQADEEEKKAQ 325
V++L+SD KV+ + +E K Q
Sbjct: 898 VQTLESDKVKLELKVKNLELQLKENKRQ 925
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 62.1 bits (144), Expect = 1e-08
Identities = 121/682 (17%), Positives = 269/682 (39%), Gaps = 67/682 (9%)
Query: 395 ECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNK 454
+ Q ++ ++ + E+ D+L + +L+ + ++ E+ EE + +L K
Sbjct: 886 DLQLQVQAEQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNA---ELTAKKRN 942
Query: 455 HKTALMELLGNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ EL ++ + + + + K + N+V L E+K ++E+
Sbjct: 943 VEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEA 1002
Query: 514 LNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE-KLQDEQNVLQSSMFIINKYKGQL 572
+ +L EDK+ + V L + +E L+ E+ V K +G L
Sbjct: 1003 HQQALDDLQAEEDKVNTLTKAK---VKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL 1059
Query: 573 K--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP------GKLEKVTEDLQ-RASAKK 623
K S L N + + + +L+K ++LQ R +
Sbjct: 1060 KLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELE 1119
Query: 624 DEILSMKSLNEKITTLKDT---EIPQLEKRIVDV--------------DTQIKTLNETVE 666
+E+ + ++ K+ L+ E+ ++ +R+ + + + + + +E
Sbjct: 1120 EELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLE 1179
Query: 667 EITMSLIEPEQKMTTAKQIHGD-MPMLDRYIQEIKTVTKKFEAVKEQ----CGDVDSEMT 721
E T+ + E ++ H D + L I ++ V +K E K + DV S M
Sbjct: 1180 EATL---QHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNME 1236
Query: 722 LDVATAKQVD-----FKQKISTLRNRVKTTQKKLN---AHNKKLQTL---YEKKTKAKEE 770
+ ++ + +++ R++ + TQ+ +N + KLQT ++ KE
Sbjct: 1237 QIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEA 1296
Query: 771 LLN--TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
L++ T+ K+ LE+ K+QL+ + A ++ L+E+ E +TE
Sbjct: 1297 LISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDL-LREQYEEETEAKA 1355
Query: 829 RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+ ++ ++ +A+ + E + KK + + +++ +EA + + K +
Sbjct: 1356 ELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLE 1415
Query: 889 TDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE 948
+ L +I+ L ++ + LD R + W+++ +E +L K
Sbjct: 1416 KTKHRLQNEIEDLMVDVERSNAAAAALDKK--QRNFDKILAEWKQKYEESQSELESSQK- 1472
Query: 949 ELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
E SL T+LF+ K +L L ++ K L++ +S D+ ++ +H
Sbjct: 1473 ---EARSL---STELFKLKNAYEESLEHL-ETFKRENKNLQEEIS-DLTEQLGSSGKTIH 1524
Query: 1009 VTKAIDKDIREYAVALDKCLME 1030
+ + K + + L L E
Sbjct: 1525 ELEKVRKQLEAEKMELQSALEE 1546
Score = 52.0 bits (119), Expect = 1e-05
Identities = 110/549 (20%), Positives = 226/549 (41%), Gaps = 45/549 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETV- 665
+LE E +AKK + S L I L+ T + ++EK + ++K L E +
Sbjct: 925 RLEDEEEMNAELTAKKRNVEDECSELKRDIDDLELT-LAKVEKEKHATENKVKNLTEEMA 983
Query: 666 --EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
+EI L + ++ + A Q D + ++ T+TK +++Q D++ +L+
Sbjct: 984 GLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLTKAKVKLEQQVDDLEG--SLE 1039
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-- 781
++D ++ L +K TQ+ + Q L E+ K EL +++D
Sbjct: 1040 QEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELNALNARIEDEQA 1099
Query: 782 --VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSA 839
L++ K+LQ+ A +E + E+ R + A S
Sbjct: 1100 LGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSC 1159
Query: 840 YI---AKVEVAFNKV-KSLDAEIQQHK------KKNVPREMEKIQEANDKLMEKQKQIMT 889
I K E F K+ + L+ QH+ +K + ++ E D L ++++
Sbjct: 1160 QIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEK 1219
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
++ ++D + + + K +L + +C R + + + + +E +N +
Sbjct: 1220 EKSEFKLELDDVTSNMEQIIKAKANL-EKMC-RTLEDQMNEHRSKAEETQRSVNDLT--- 1274
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
+++ L + +L +Q E +S+L + + +LE L + +E++ + K H
Sbjct: 1275 -SQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE-DLKRQLEEEVKAKNALAHA 1332
Query: 1010 TKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGN 1066
++ D +RE + E R + N + + WR Y + D I+ +TE
Sbjct: 1333 LQSARHDCDLLREQYEEETEAKAELQR-VLSKANSEVAQ-WRTKY---ETDAIQ-RTE-- 1384
Query: 1067 LTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACL--IIRLALAETFSSRFGILAL 1124
+E ++K R+ +++ VE + +CS+ +K L I + + S AL
Sbjct: 1385 -ELEEAKKKLAQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1442
Query: 1125 DEPTTNLDQ 1133
D+ N D+
Sbjct: 1443 DKKQRNFDK 1451
Score = 44.4 bits (100), Expect = 0.002
Identities = 145/866 (16%), Positives = 325/866 (37%), Gaps = 67/866 (7%)
Query: 173 KVKERFDEIFDADKYSDCLDRLKKIRKDYAQ-------NLKLLENYATTVKAKQKELEDS 225
K K + ++ D L++ KK+R D + +LKL + ++ +++L++
Sbjct: 1022 KAKVKLEQ--QVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDER 1079
Query: 226 YKKNT-SFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIEN-- 282
KK N +I +E++ K L+++ +E ++ + AK+ ++ +
Sbjct: 1080 LKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDL 1139
Query: 283 ---ITEVQTN-EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQX 338
+ E+ EEA AT +E + K + + QK + D EE Q E + +
Sbjct: 1140 SRELEEISERLEEAGGATSCQIEM--NKKREAEFQKMRRDLEEATLQ---HEATAAALRK 1194
Query: 339 XXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQ 398
+S +A E +
Sbjct: 1195 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
++NE E+ ++ +++L+ + KLQ + +L + L KE + L T
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQ------LDEKEALISQLTRGKLTY 1308
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
+L + + V +AE + + N
Sbjct: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEV 1368
Query: 519 SEL-TKAE-DKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNS 576
++ TK E D I + T+ + K +++ ++ + + + K K +L++
Sbjct: 1369 AQWRTKYETDAIQR---TEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEI 1425
Query: 577 CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKI 636
+ + N + + K + + S++K+ +SL+ ++
Sbjct: 1426 EDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEA----RSLSTEL 1481
Query: 637 TTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI 696
LK+ LE + + K L E + ++T L + + +++ L+
Sbjct: 1482 FKLKNAYEESLE-HLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVR---KQLEAEK 1537
Query: 697 QEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK 756
E+++ ++ EA E L+ K + ++K++ ++ ++
Sbjct: 1538 MELQSALEEAEASLEHEEGKILRAQLEFNQIK-AEIERKLAEKDEEMEQAKRNHLRVVDS 1596
Query: 757 LQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVAL 816
LQT + +T+++ E L +KK++ +N +++ + L+ L
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGDLN------EMEIQLSHANRMAAEAQKQVKSLQSLL 1650
Query: 817 KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ--HKKKNVPREM---- 870
K+ + VR N DL E A + + +++ L A ++Q +K RE+
Sbjct: 1651 KDTQIQLDDAVRANDDLKE-NIAIVERRNNLQAELEELRAVVEQTERSRKLADRELIETS 1709
Query: 871 EKIQ---EANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAK-QEVYKRDLDDNLC----LR 922
E++Q N L+ ++K++ D L +++ E +E K+ + D L+
Sbjct: 1710 ERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELK 1769
Query: 923 KAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
K Q + ++ + + + + + L+E E + +K K QK E + EL+ L+
Sbjct: 1770 KEQDTSAHLERMKKNMEQTIKDL-QHRLDEAEQIALKGGKKQLQKLE--ARVRELENELE 1826
Query: 983 GFRNELEKSLS--KDIEKKFREKMYE 1006
+ +S+ + E++ +E Y+
Sbjct: 1827 AEQKRNAESVKGMRKSERRIKELTYQ 1852
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 62.1 bits (144), Expect = 1e-08
Identities = 97/455 (21%), Positives = 203/455 (44%), Gaps = 44/455 (9%)
Query: 604 NVPGKLEKVTEDLQRASAKKDE-----ILSMKSLNE-------KITTLKDTE--IPQLEK 649
N+ + EK E+L + AK+ E + M+ N+ + +L D E QL K
Sbjct: 855 NMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIK 914
Query: 650 RIVDVDTQIKTLNETV---EEITMSLIEPEQKM-TTAKQIHGDMPMLDRYIQEIKTVTKK 705
+ ++ +IK + E EEI L ++K+ ++ D+ L+ + +++ K+
Sbjct: 915 TKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE---KE 971
Query: 706 FEAVKEQCGDVDSEMT-LDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKK 764
A + + ++ EM LD AK K+K L+ + T L A K+ TL + K
Sbjct: 972 KHATENKVKNLTEEMAGLDETIAKLT--KEK-KALQEAHQQTLDDLQAEEDKVNTLTKAK 1028
Query: 765 TKAKEEL------LNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
K ++++ L +KK++ ++LE +K++L+ D L+ LK+
Sbjct: 1029 IKLEQQVDDLEGSLEQEKKIR--MDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKK 1086
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
K + + + D G K++ +++ L+ EI+ + E ++ + +
Sbjct: 1087 KEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR-SDLSR 1145
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD-- 936
+L E +++ + +I+ K A+ + +RDL++ L+ T T +K D
Sbjct: 1146 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE-ATLQHEATAATLRKKHADSV 1204
Query: 937 -ELNEKLNGIN--KEEL-NEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
EL E+++ + K++L EK + ++ L + A L+K + ++L +
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
Query: 993 SKDIEKKFREKMYELHVTKA-IDKDIREYAVALDK 1026
+K+ E+ + + +L +A + + EY+ LD+
Sbjct: 1265 TKEEEQ--QRLINDLTAQRARLQTESGEYSRQLDE 1297
Score = 60.1 bits (139), Expect = 5e-08
Identities = 170/921 (18%), Positives = 387/921 (42%), Gaps = 94/921 (10%)
Query: 71 KVNRSTEVLGQVKLKI-VNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTK 129
KVN T+ ++KL+ V+ + LE + +++ L + K K L+ L ES T
Sbjct: 1020 KVNTLTKA--KIKLEQQVDDLEGSLEQEKKIRMD-LERAKRK---LEGDLKLAQES--TM 1071
Query: 130 DVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKE---RFDEI---FD 183
D+ + LD E+L + ++ + +++ + + KK+KE R +E+ +
Sbjct: 1072 DIENDKQQLD----EKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIE 1127
Query: 184 ADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK-----EEE 237
A++ S + +K R D ++ L+ + E A ++E + K+ F K EE
Sbjct: 1128 AERASRA--KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEA 1185
Query: 238 KIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQTNEEAENA 295
+ +E ++ + K ++ E+ID +R +Q +E K I ++ +N E +
Sbjct: 1186 TLQHEATAATLR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSK 1244
Query: 296 TKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXX 355
K LEK+ D Q S+ +E++ Q +++ + +
Sbjct: 1245 AKGNLEKMCRALED---QLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTL 1301
Query: 356 XXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMD 415
++ ++ +A++ L Q ++ + EQYE+E +
Sbjct: 1302 ----VSQLSRGKQAFTQQIEELKRQLEEEIKAKSAL-AHALQSSRHDCDLLREQYEEEQE 1356
Query: 416 ---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDF- 471
EL + ++K + A+ + K + +T+E L K K L + +V +
Sbjct: 1357 AKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEEHVEAVNAK 1414
Query: 472 AVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE--RRSELTKAE---- 525
++ K + ++NEV L+ ++++ + L E ++ E T AE
Sbjct: 1415 CASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEAS 1474
Query: 526 DKIYKACGTQPYDV--TLSKYTTTVEKLQDEQNVLQSSMFIINKY--KGQLKDNSCCPLC 581
K ++ T+ + + + +E L+ E LQ + + + +G + + +
Sbjct: 1475 QKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIK 1534
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKD 641
+ + +SE + GK+ ++ +L + ++ D ++ K +E+I +K
Sbjct: 1535 KQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK--DEEIDQMKR 1592
Query: 642 TEIPQLEKRIVDVDTQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE 698
I +E +D +I++ N+ + +++ L E E ++ A ++ + L Y
Sbjct: 1593 NHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEA--LRNY--- 1647
Query: 699 IKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQ 758
+ +A+ + D+++ LD A Q D K++++ + R Q ++ L+
Sbjct: 1648 -----RNTQAILK-----DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLE 1697
Query: 759 TLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEV 814
+ A++ELL+ ++VQ + +L +KK+L++D E
Sbjct: 1698 QTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEE 1757
Query: 815 ALKEKI---EAKTEVVRRNRDLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPREM 870
K+ I E +++ +D SA++ +++ + VK L + + ++ +
Sbjct: 1758 KAKKAITDAAMMAEELKKEQDT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGK 1813
Query: 871 EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCLR------ 922
++IQ+ ++ E + ++ ++++ + + L+ + K+ Y+ + D LR
Sbjct: 1814 KQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVD 1873
Query: 923 KAQTDITNWQKQDDELNEKLN 943
K Q + ++++Q +E E+ N
Sbjct: 1874 KLQAKVKSYKRQAEEAEEQSN 1894
Score = 50.0 bits (114), Expect = 5e-05
Identities = 108/626 (17%), Positives = 256/626 (40%), Gaps = 44/626 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIE-ENLKT 443
K AE E + ++E + ++ + + E + EL +K+ L ++ L+ + E ++L
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLAD 904
Query: 444 KEK---QLIVLKNKHKTALMELLGNVP-EKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
E+ QLI K + + + E+ E++ + + ++ +E
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E+ + E+ ++ I K T+ + T++ LQ E++ +
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKL--TKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
+ K + Q+ D E E + ++ T D++
Sbjct: 1023 TLTKAKIKLEQQVDD------LEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIEND 1076
Query: 620 SAKKDEILSMKS--LNEKITTLKDTEI--PQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
+ DE L K ++ + ++D + QL+K+I ++ +I+ L E +E S +
Sbjct: 1077 KQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKA 1136
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDVDSEMTLDVATAKQVDFKQ 734
E++ + + ++ + ++E T + E K++ + +M D+ A + +
Sbjct: 1137 EKQRS---DLSRELEEISERLEEAGGATSAQIEMNKKREAEF-QKMRRDLEEA-TLQHEA 1191
Query: 735 KISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSD 794
+TLR + + +L LQ + +K K K E+ + ++ D+ + E+ + + +
Sbjct: 1192 TAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEM---KMEIDDLASNMETVSKAKGN 1248
Query: 795 CXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSL 854
I E + I T +R R E+G Y +++ V L
Sbjct: 1249 LEKMCRALEDQLSEIKTKEEEQQRLINDLT--AQRARLQTESGE-YSRQLDEKDTLVSQL 1305
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
K+ +++E+++ ++ ++ + + Q D L+++ +++ K +
Sbjct: 1306 -----SRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAE 1360
Query: 915 LDDNLCLRKAQTDITNWQ-KQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA 973
L + KA +++ W+ K + + ++ EEL E + + ++ + ++ E A
Sbjct: 1361 L--QRAMSKANSEVAQWRTKYETDAIQR-----TEELEEAKKKLAQRLQDAEEHVEAVNA 1413
Query: 974 -LSELKKSLKGFRNELEKSLSKDIEK 998
+ L+K+ + +NE+E L D+E+
Sbjct: 1414 KCASLEKTKQRLQNEVE-DLMIDVER 1438
Score = 46.8 bits (106), Expect = 5e-04
Identities = 120/677 (17%), Positives = 257/677 (37%), Gaps = 67/677 (9%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQKI------TKLQKQTAKL 431
K E + IEE ++EI + EK +E++E+S+++ T Q + K
Sbjct: 1111 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKK 1170
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E L+ KH ++ EL + + + K + E++
Sbjct: 1171 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKM 1230
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE K R +L ++ SE+ E++ + D+T +
Sbjct: 1231 EIDDLASNMETVSKAKGNLE---KMCR-ALEDQLSEIKTKEEEQQRLIN----DLTAQRA 1282
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
E + + + + + +G+ R E E + +
Sbjct: 1283 RLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRH 1342
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
L + E+ Q A A+ +M N ++ + K D + + L E
Sbjct: 1343 DCDLLREQYEEEQEAKAELQR--AMSKANSEVAQWR-------TKYETDAIQRTEELEEA 1393
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ-EIKTVTKKFEAVKEQCGDVDSEMTLD 723
+++ L + E+ + + + +Q E++ + E C +D
Sbjct: 1394 KKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDK----- 1448
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
KQ +F + ++ + + + T +L A K+ ++L + K K ++ + +
Sbjct: 1449 ----KQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAY---EESLDQLET 1501
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGSAY 840
L+ K LQ + I L+ K+ + K+E+ + +E
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAALEEAEASLEHEEGK 1561
Query: 841 IAKVEVAFNKVKS-LDAEIQQHKKK--NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
I ++++ N+VKS +D +I + ++ + R +I E+ ++ + + D L KK
Sbjct: 1562 ILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1621
Query: 898 I--DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQ-DDELNEKLNGINKEELNEKE 954
+ D + EI + + R Q + + Q DD L ++E+L E+
Sbjct: 1622 MEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALR------SQEDLKEQL 1675
Query: 955 SLIIKQTKLFQQK-AECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAI 1013
+++ ++ L Q + E L + ++S K EL S+ ++ + ++ K +
Sbjct: 1676 AMVERRANLLQAEIEELRATLEQTERSRKIAEQEL-LDASERVQLLHTQNTSLINTKKKL 1734
Query: 1014 DKDIREYAVALDKCLME 1030
+ DI + ++ + E
Sbjct: 1735 ETDISQIQGEMEDIIQE 1751
Score = 44.0 bits (99), Expect = 0.003
Identities = 38/164 (23%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDI-TNWQKQ 934
K+ K T++++ K + K+E+AK E +++L++ + L + + D+ Q +
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
Query: 935 DDEL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
D L E+ + + K ++ + E+ I + T+ + + E L+ K+ L+ +EL+K
Sbjct: 899 ADSLADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + E H T+ K++ E LD+ + + +EK
Sbjct: 958 ID-DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK 1000
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 62.1 bits (144), Expect = 1e-08
Identities = 97/455 (21%), Positives = 203/455 (44%), Gaps = 44/455 (9%)
Query: 604 NVPGKLEKVTEDLQRASAKKDE-----ILSMKSLNE-------KITTLKDTE--IPQLEK 649
N+ + EK E+L + AK+ E + M+ N+ + +L D E QL K
Sbjct: 855 NMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIK 914
Query: 650 RIVDVDTQIKTLNETV---EEITMSLIEPEQKM-TTAKQIHGDMPMLDRYIQEIKTVTKK 705
+ ++ +IK + E EEI L ++K+ ++ D+ L+ + +++ K+
Sbjct: 915 TKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVE---KE 971
Query: 706 FEAVKEQCGDVDSEMT-LDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKK 764
A + + ++ EM LD AK K+K L+ + T L A K+ TL + K
Sbjct: 972 KHATENKVKNLTEEMAGLDETIAKLT--KEK-KALQEAHQQTLDDLQAEEDKVNTLTKAK 1028
Query: 765 TKAKEEL------LNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
K ++++ L +KK++ ++LE +K++L+ D L+ LK+
Sbjct: 1029 IKLEQQVDDLEGSLEQEKKIR--MDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKK 1086
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
K + + + D G K++ +++ L+ EI+ + E ++ + +
Sbjct: 1087 KEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQR-SDLSR 1145
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD-- 936
+L E +++ + +I+ K A+ + +RDL++ L+ T T +K D
Sbjct: 1146 ELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEE-ATLQHEATAATLRKKHADSV 1204
Query: 937 -ELNEKLNGIN--KEEL-NEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
EL E+++ + K++L EK + ++ L + A L+K + ++L +
Sbjct: 1205 AELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK 1264
Query: 993 SKDIEKKFREKMYELHVTKA-IDKDIREYAVALDK 1026
+K+ E+ + + +L +A + + EY+ LD+
Sbjct: 1265 TKEEEQ--QRLINDLTAQRARLQTESGEYSRQLDE 1297
Score = 59.3 bits (137), Expect = 8e-08
Identities = 144/809 (17%), Positives = 335/809 (41%), Gaps = 75/809 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ S + +K R D ++ L+ + E A ++E + K+ F K
Sbjct: 1120 EELEEEIEAERASRA--KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQK 1177
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K I ++
Sbjct: 1178 MRRDLEEATLQHEATAATLR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1236
Query: 288 TNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXX 347
+N E + K LEK+ D Q S+ +E++ Q +++ + +
Sbjct: 1237 SNMETVSKAKGNLEKMCRALED---QLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSR 1293
Query: 348 XXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAV 407
++ ++ +A++ L Q ++ +
Sbjct: 1294 QLDEKDTL----VSQLSRGKQAFTQQIEELKRQLEEEIKAKSAL-AHALQSSRHDCDLLR 1348
Query: 408 EQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLG 464
EQYE+E + EL + ++K + A+ + K + +T+E L K K L +
Sbjct: 1349 EQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEE 1406
Query: 465 NVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE--RRSEL 521
+V + ++ K + ++NEV L+ ++++ + L E ++ E
Sbjct: 1407 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1466
Query: 522 TKAE----DKIYKACGTQPYDV--TLSKYTTTVEKLQDEQNVLQSSMFIINKY--KGQLK 573
T AE K ++ T+ + + + +E L+ E LQ + + + +G +
Sbjct: 1467 THAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1526
Query: 574 DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN 633
+ + + + +SE + GK+ ++ +L + ++ D ++ K +
Sbjct: 1527 IHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK--D 1584
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMP 690
E+I +K I +E +D +I++ N+ + +++ L E E ++ A ++ +
Sbjct: 1585 EEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEA- 1643
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
L Y + +A+ + D+++ LD A Q D K++++ + R Q ++
Sbjct: 1644 -LRNY--------RNTQAILK-----DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEI 1689
Query: 751 NAHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXX 806
L+ + A++ELL+ ++VQ + +L +KK+L++D
Sbjct: 1690 EELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDII 1749
Query: 807 XAITPLEVALKEKI---EAKTEVVRRNRDLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHK 862
E K+ I E +++ +D SA++ +++ + VK L + + +
Sbjct: 1750 QEARNAEEKAKKAITDAAMMAEELKKEQDT----SAHLERMKKNLEQTVKDLQHRLDEAE 1805
Query: 863 KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLK--DEIAKQEVYKRDLDDNLC 920
+ + ++IQ+ ++ E + ++ ++++ + + L+ + K+ Y+ + D
Sbjct: 1806 QLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNI 1865
Query: 921 LR------KAQTDITNWQKQDDELNEKLN 943
LR K Q + ++++Q +E E+ N
Sbjct: 1866 LRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1894
Score = 48.8 bits (111), Expect = 1e-04
Identities = 114/608 (18%), Positives = 253/608 (41%), Gaps = 63/608 (10%)
Query: 395 ECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNK 454
+ Q ++ + ++ E+ D+L + TK+Q + AK+KE E+ + +L K K
Sbjct: 890 DLQLQVQAEADSLADAEERCDQLIK--TKIQLE-AKIKEVTERAEDEEEINAELTAKKRK 946
Query: 455 HKTALMELLGNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ EL ++ + + + + K + N+V L E+K ++E+
Sbjct: 947 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEA 1006
Query: 514 LNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLK 573
+ +L EDK+ TL+K +E+ D+ L+ S+ K + L+
Sbjct: 1007 HQQTLDDLQAEEDKVN----------TLTKAKIKLEQQVDD---LEGSLEQEKKIRMDLE 1053
Query: 574 DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN 633
R E + + M++ +++ E L KK E M L
Sbjct: 1054 R------AKRKLEGDLKLAQESA------MDIENDKQQLDEKL-----KKKEF-EMSGLQ 1095
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
KI + + QL+K+I ++ +I+ L E +E S + E++ + + ++ +
Sbjct: 1096 SKIEDEQALGM-QLQKKIKELQARIEELEEEIEAERASRAKAEKQRS---DLSRELEEIS 1151
Query: 694 RYIQEIKTVTK-KFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNA 752
++E T + E K++ + +M D+ A + + +TLR + + +L
Sbjct: 1152 ERLEEAGGATSAQIEMNKKREAEF-QKMRRDLEEA-TLQHEATAATLRKKHADSVAELGE 1209
Query: 753 HNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPL 812
LQ + +K K K E+ + ++ D+ + E+ + + + I
Sbjct: 1210 QIDNLQRVKQKLEKEKSEM---KMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTK 1266
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK 872
E + I T +R R E+G Y +++ V L K+ +++E+
Sbjct: 1267 EEEQQRLINDLT--AQRARLQTESGE-YSRQLDEKDTLVSQL-----SRGKQAFTQQIEE 1318
Query: 873 IQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQ 932
++ ++ ++ + + Q D L+++ +++ K +L + KA +++ W+
Sbjct: 1319 LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAEL--QRAMSKANSEVAQWR 1376
Query: 933 -KQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA-LSELKKSLKGFRNELEK 990
K + + ++ EEL E + + ++ + ++ E A + L+K+ + +NE+E
Sbjct: 1377 TKYETDAIQR-----TEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVE- 1430
Query: 991 SLSKDIEK 998
L D+E+
Sbjct: 1431 DLMIDVER 1438
Score = 48.4 bits (110), Expect = 2e-04
Identities = 121/677 (17%), Positives = 257/677 (37%), Gaps = 67/677 (9%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQKI------TKLQKQTAKL 431
K E + IEE ++EI + EK +E++E+S+++ T Q + K
Sbjct: 1111 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKK 1170
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E L+ KH ++ EL + + + K + E++
Sbjct: 1171 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKM 1230
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE K R +L ++ SE+ E++ + D+T +
Sbjct: 1231 EIDDLASNMETVSKAKGNLE---KMCR-ALEDQLSEIKTKEEEQQRLIN----DLTAQRA 1282
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
E + + + + + +G+ R E E + +
Sbjct: 1283 RLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRH 1342
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
L + E+ Q A A+ +M N ++ + K D + + L E
Sbjct: 1343 DCDLLREQYEEEQEAKAELQR--AMSKANSEVAQWR-------TKYETDAIQRTEELEEA 1393
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ-EIKTVTKKFEAVKEQCGDVDSEMTLD 723
+++ L + E+ + + + +Q E++ + E C +D
Sbjct: 1394 KKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDK----- 1448
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
KQ +F + ++ + + + T +L A K+ ++L + K K ++ + +
Sbjct: 1449 ----KQRNFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAY---EESLDQLET 1501
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGSAY 840
L+ K LQ + I LE K+ + K+E+ + +E
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGK 1561
Query: 841 IAKVEVAFNKVKS-LDAEIQQHKKK--NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
I ++++ N+VKS +D +I + ++ + R +I E+ ++ + + D L KK
Sbjct: 1562 ILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKK 1621
Query: 898 I--DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQ-DDELNEKLNGINKEELNEKE 954
+ D + EI + + R Q + + Q DD L ++E+L E+
Sbjct: 1622 MEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALR------SQEDLKEQL 1675
Query: 955 SLIIKQTKLFQQK-AECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAI 1013
+++ ++ L Q + E L + ++S K EL S+ ++ + ++ K +
Sbjct: 1676 AMVERRANLLQAEIEELRATLEQTERSRKIAEQEL-LDASERVQLLHTQNTSLINTKKKL 1734
Query: 1014 DKDIREYAVALDKCLME 1030
+ DI + ++ + E
Sbjct: 1735 ETDISQIQGEMEDIIQE 1751
Score = 44.0 bits (99), Expect = 0.003
Identities = 38/164 (23%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDI-TNWQKQ 934
K+ K T++++ K + K+E+AK E +++L++ + L + + D+ Q +
Sbjct: 839 KIKPLLKSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
Query: 935 DDEL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
D L E+ + + K ++ + E+ I + T+ + + E L+ K+ L+ +EL+K
Sbjct: 899 ADSLADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 957
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + E H T+ K++ E LD+ + + +EK
Sbjct: 958 ID-DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK 1000
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 61.7 bits (143), Expect = 2e-08
Identities = 115/637 (18%), Positives = 263/637 (41%), Gaps = 51/637 (8%)
Query: 384 HKQAEN---ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-K 432
H QAE + NI+E ++++ E+E A ++ + E K+ KL++ Q KL K
Sbjct: 933 HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAK 992
Query: 433 EKEMIEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEV 482
EK+++E+ + + K K L LKNKH+ + +L + ++ K E+
Sbjct: 993 EKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE------KQRQEL 1046
Query: 483 RNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS 542
L+A+ ++ L ++ EL A ++ + + ++ L
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK--NMALK 1104
Query: 543 KYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD-NSCCPLCNRGFENESEXXXXXXXXXXX 601
K ++ + Q L+S NK + Q +D E+ +
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
L+K E + A + +I M+ + + ++ Q ++ +++ +TL
Sbjct: 1165 REQEVNILKKTLE--EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 662 ----NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTV-TKKFEAVKEQCGDV 716
E E+ + L K++ + L E + V T+ + V + ++
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 717 DSEM-TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
D+ L + +K + S L ++++ TQ+ L N++ +L K + ++E + +
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
+++++ EE+K L+ + L+ E K ++ +DL
Sbjct: 1343 EQLEE---EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL---QKDLEG 1396
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQK---QIMTDRQ 892
+ KV A++K++ +QQ + ++ +++ +++ L +KQK Q++ + +
Sbjct: 1397 LSQRHEEKV-AAYDKLEKTKTRLQQ-ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
++ K +D A+ E +++ L L +A + + + + LN++ ++ ++
Sbjct: 1455 TISAKYAEERDR-AEAEAREKE-TKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS 1512
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
K+ + +L + K + E+K L+ +EL+
Sbjct: 1513 KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 60.1 bits (139), Expect = 5e-08
Identities = 152/743 (20%), Positives = 305/743 (41%), Gaps = 78/743 (10%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
E L EE Q++ E EK + E + +LS +I +LQ Q A+LK + L KE++
Sbjct: 1033 EERLRREEKQRQ--ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ------LAKKEEE 1084
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
L + AL + +K+ A + K E+ +++ E ++
Sbjct: 1085 L-------QAALARVEEEAAQKNMA--LKKIR-ELESQISELQEDLESERASRNKAEKQK 1134
Query: 508 KHIRESLNERRSELTKAEDKI---YKACGTQPYDVTLSKYTTTVEKLQDE---QNVLQSS 561
+ + E L ++EL D + + +V + K T E E Q + Q
Sbjct: 1135 RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH 1194
Query: 562 MFIINKYKGQLKDNSCCPL----CNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + QL+ + ENE E + K +KV L
Sbjct: 1195 SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Query: 617 QRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
Q K +E +++ L +K+T L+ E+ + + D++ L + + L +
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKLQ-VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT 1313
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT--AKQVDFK 733
++ + ++ + L +++++ F E+ + + +AT A+ D K
Sbjct: 1314 QELL---QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370
Query: 734 QKISTLRNRVKTTQ---KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN--LEESK 788
+K+ ++T + +KL + L +E+K A ++L T+ ++Q ++ L +
Sbjct: 1371 KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
Q QS C ++ +EK + R+R EA + +A
Sbjct: 1431 HQRQSACNLEKKQKKFD-------QLLAEEKTISAKYAEERDRAEAEAREKETKALSLAR 1483
Query: 849 NKVKSLDAEIQQHK-KKNVPREMEKIQEANDKL------MEKQKQIMTDR-QVLTKKIDT 900
++++ + + + K EME + + D + +EK K+ + + + + +++
Sbjct: 1484 ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
L+DE+ E K L+ NL KAQ + + Q +D++ EK + + ++ E E+ + +
Sbjct: 1544 LEDELQATEDAKLRLEVNLQAMKAQFE-RDLQGRDEQSEEKKKQLVR-QVREMEAELEDE 1601
Query: 961 TKLFQQKAECTGALSELKKSLKGF----------RNELEKSLSKDIEKKFREKMYELHVT 1010
K Q++ A +L+ LK R+E K L K ++ + ++ M EL T
Sbjct: 1602 RK---QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK-LQAQMKDCMRELDDT 1657
Query: 1011 KAIDKDIREYAVALDKCL--MEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT---EG 1065
+A ++I A +K L ME +++ R+ + D EI +G
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 1066 NLTVESERRKYDYRVVQSKNGVE 1088
L +E E+R+ + R+ Q + +E
Sbjct: 1718 ALALE-EKRRLEARIAQLEEELE 1739
Score = 54.8 bits (126), Expect = 2e-06
Identities = 119/656 (18%), Positives = 271/656 (41%), Gaps = 46/656 (7%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN 453
+E ++ ++ E VE+ E+ L + K+Q+ +L E+++ EE ++ QL +
Sbjct: 911 QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQEL-EEQLEEEESARQKLQLEKVTT 969
Query: 454 KHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ K +E + + + C++ E E + K + +
Sbjct: 970 EAKLKKLE--------EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 514 LNERRSELTKAEDKIYK-ACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQL 572
N+ + +T E+++ + Q + T K L D+ LQ+ I + K QL
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ---IAELKMQL 1078
Query: 573 KDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL--QRASAKKDEILSMK 630
E + ++ ++ EDL +RAS K E +
Sbjct: 1079 AKKE--EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAE-KQKR 1135
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMP 690
L E++ LK TE+ ++++ E I +E E K T QI
Sbjct: 1136 DLGEELEALK-TELEDTLDSTA-AQQELRSKREQEVNILKKTLEEEAK-THEAQI---QE 1189
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAKQVDFKQKISTLRNRVKTTQKK 749
M ++ Q ++ + ++ E K +++ ++ TL+ + + + + + + +KK
Sbjct: 1190 MRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKK 1249
Query: 750 LNAHNKKLQTLYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXA 808
+ A ++LQ + + + + EL + K+Q ++ N+ Q S
Sbjct: 1250 VEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQ 1309
Query: 809 ITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ-HKK-KNV 866
+ + L+E+ K + + + + + +++ ++E +L+ +I H + ++
Sbjct: 1310 LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADM 1369
Query: 867 PREMEKIQEANDKLMEKQKQIMTDRQVLTKKID---TLKDEIAKQEV-YKRDLDDNLC-- 920
++ME + E ++++ D + L+++ + D++ K + +++LDD L
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Query: 921 --LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLII----KQTK---LFQQKAECT 971
R++ ++ QK+ D+L + I+ + E++ K+TK L + E
Sbjct: 1430 DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 972 GALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIREYAVALDK 1026
+EL++ K FR E+E +S + + ++EL +K A+++ + E L++
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSS--KDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543
Score = 44.4 bits (100), Expect = 0.002
Identities = 139/872 (15%), Positives = 338/872 (38%), Gaps = 73/872 (8%)
Query: 70 AKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTK 129
A+ N + + + +++ +I ++ LE R+ + A +K+ + L++ + +++ T
Sbjct: 1097 AQKNMALKKIRELESQISELQE-DLESERASRNKAEKQKRDLGEELEALKTELED---TL 1152
Query: 130 DVSSRCADLDILMHEELGVSKAILNSVVFCHQED-SSWPLDEGKKVKERFDEIFDADKYS 188
D ++ +L +E+ + K L H+ + V+E +++ +
Sbjct: 1153 DSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVK 1212
Query: 189 DCLDRLKKI----RKDYAQNLKLLENYATTVKAKQKELEDSYKK-NTSFNKEEE---KIA 240
L++ K+ R + A +K+L + K+K++E ++ FN+ E ++A
Sbjct: 1213 ANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELA 1272
Query: 241 NEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENAT-KTI 299
++ + ++E + L SQ+ K K + +A +++++ E+ E + + T
Sbjct: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDF--SALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 300 LEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXD 359
L++VE K+ + Q +EEE+ + + H Q
Sbjct: 1331 LKQVEDEKNSFR---EQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVK 1387
Query: 360 ITSANQSXXXXXXXXXXXXXXXXXHK-QAENELNIEECQQEINEDEKAVEQYEQEMDELS 418
K + + +++ +++ ++ E++ +
Sbjct: 1388 RKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFD 1447
Query: 419 QKITKLQKQTAKL-KEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINK 477
Q + + + +AK +E++ E + KE + + L AL E + E + +NK
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEAREKETKALSLAR----ALEEAMEQKAELE---RLNK 1500
Query: 478 FECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-P 536
+ R E+ LE ++ + + + E +++L + ED++ +
Sbjct: 1501 ---QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLR 1557
Query: 537 YDVTLSKYTTTVEK-LQ--DEQNVLQSSMFI--INKYKGQLKDN----SCCPLCNRGFEN 587
+V L E+ LQ DEQ+ + + + + + +L+D S + E
Sbjct: 1558 LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEM 1617
Query: 588 ESEXXXXXXXXXXXXMN--------VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTL 639
+ + + + +++ +L A ++EIL+ NEK
Sbjct: 1618 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKS 1677
Query: 640 KDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI 699
+ E+ QL++ + + + + +E+ + K A + + L+ I ++
Sbjct: 1678 MEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALE---EKRRLEARIAQL 1734
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT 759
+ E ++E+ G ++E+ D + Q + L QK NA + +
Sbjct: 1735 E------EELEEEQG--NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQ 1786
Query: 760 LYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
E K K +E + K + I LE QL+ + E LK+
Sbjct: 1787 NKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
+ + + RRN + Y + + A ++K L ++++ ++ E ++ +
Sbjct: 1847 -VLLQVDDERRNAE------QYKDQADKASTRLKQLKRQLEEAEE-----EAQRANASRR 1894
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
KL + + + +++ +LK+++ + ++
Sbjct: 1895 KLQRELEDATETADAMNREVSSLKNKLRRGDL 1926
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 61.7 bits (143), Expect = 2e-08
Identities = 115/637 (18%), Positives = 263/637 (41%), Gaps = 51/637 (8%)
Query: 384 HKQAEN---ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-K 432
H QAE + NI+E ++++ E+E A ++ + E K+ KL++ Q KL K
Sbjct: 933 HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAK 992
Query: 433 EKEMIEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEV 482
EK+++E+ + + K K L LKNKH+ + +L + ++ K E+
Sbjct: 993 EKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE------KQRQEL 1046
Query: 483 RNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS 542
L+A+ ++ L ++ EL A ++ + + ++ L
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK--NMALK 1104
Query: 543 KYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD-NSCCPLCNRGFENESEXXXXXXXXXXX 601
K ++ + Q L+S NK + Q +D E+ +
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
L+K E + A + +I M+ + + ++ Q ++ +++ +TL
Sbjct: 1165 REQEVNILKKTLE--EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 662 ----NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTV-TKKFEAVKEQCGDV 716
E E+ + L K++ + L E + V T+ + V + ++
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 717 DSEM-TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
D+ L + +K + S L ++++ TQ+ L N++ +L K + ++E + +
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
+++++ EE+K L+ + L+ E K ++ +DL
Sbjct: 1343 EQLEE---EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL---QKDLEG 1396
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQK---QIMTDRQ 892
+ KV A++K++ +QQ + ++ +++ +++ L +KQK Q++ + +
Sbjct: 1397 LSQRHEEKV-AAYDKLEKTKTRLQQ-ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
++ K +D A+ E +++ L L +A + + + + LN++ ++ ++
Sbjct: 1455 TISAKYAEERDR-AEAEAREKE-TKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS 1512
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
K+ + +L + K + E+K L+ +EL+
Sbjct: 1513 KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 60.1 bits (139), Expect = 5e-08
Identities = 152/743 (20%), Positives = 305/743 (41%), Gaps = 78/743 (10%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
E L EE Q++ E EK + E + +LS +I +LQ Q A+LK + L KE++
Sbjct: 1033 EERLRREEKQRQ--ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ------LAKKEEE 1084
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
L + AL + +K+ A + K E+ +++ E ++
Sbjct: 1085 L-------QAALARVEEEAAQKNMA--LKKIR-ELESQISELQEDLESERASRNKAEKQK 1134
Query: 508 KHIRESLNERRSELTKAEDKI---YKACGTQPYDVTLSKYTTTVEKLQDE---QNVLQSS 561
+ + E L ++EL D + + +V + K T E E Q + Q
Sbjct: 1135 RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH 1194
Query: 562 MFIINKYKGQLKDNSCCPL----CNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + QL+ + ENE E + K +KV L
Sbjct: 1195 SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Query: 617 QRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
Q K +E +++ L +K+T L+ E+ + + D++ L + + L +
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKLQ-VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT 1313
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT--AKQVDFK 733
++ + ++ + L +++++ F E+ + + +AT A+ D K
Sbjct: 1314 QELL---QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370
Query: 734 QKISTLRNRVKTTQ---KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN--LEESK 788
+K+ ++T + +KL + L +E+K A ++L T+ ++Q ++ L +
Sbjct: 1371 KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
Q QS C ++ +EK + R+R EA + +A
Sbjct: 1431 HQRQSACNLEKKQKKFD-------QLLAEEKTISAKYAEERDRAEAEAREKETKALSLAR 1483
Query: 849 NKVKSLDAEIQQHK-KKNVPREMEKIQEANDKL------MEKQKQIMTDR-QVLTKKIDT 900
++++ + + + K EME + + D + +EK K+ + + + + +++
Sbjct: 1484 ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
L+DE+ E K L+ NL KAQ + + Q +D++ EK + + ++ E E+ + +
Sbjct: 1544 LEDELQATEDAKLRLEVNLQAMKAQFE-RDLQGRDEQSEEKKKQLVR-QVREMEAELEDE 1601
Query: 961 TKLFQQKAECTGALSELKKSLKGF----------RNELEKSLSKDIEKKFREKMYELHVT 1010
K Q++ A +L+ LK R+E K L K ++ + ++ M EL T
Sbjct: 1602 RK---QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK-LQAQMKDCMRELDDT 1657
Query: 1011 KAIDKDIREYAVALDKCL--MEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT---EG 1065
+A ++I A +K L ME +++ R+ + D EI +G
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 1066 NLTVESERRKYDYRVVQSKNGVE 1088
L +E E+R+ + R+ Q + +E
Sbjct: 1718 ALALE-EKRRLEARIAQLEEELE 1739
Score = 54.8 bits (126), Expect = 2e-06
Identities = 119/656 (18%), Positives = 271/656 (41%), Gaps = 46/656 (7%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN 453
+E ++ ++ E VE+ E+ L + K+Q+ +L E+++ EE ++ QL +
Sbjct: 911 QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQEL-EEQLEEEESARQKLQLEKVTT 969
Query: 454 KHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ K +E + + + C++ E E + K + +
Sbjct: 970 EAKLKKLE--------EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 514 LNERRSELTKAEDKIYK-ACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQL 572
N+ + +T E+++ + Q + T K L D+ LQ+ I + K QL
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ---IAELKMQL 1078
Query: 573 KDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL--QRASAKKDEILSMK 630
E + ++ ++ EDL +RAS K E +
Sbjct: 1079 AKKE--EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAE-KQKR 1135
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMP 690
L E++ LK TE+ ++++ E I +E E K T QI
Sbjct: 1136 DLGEELEALK-TELEDTLDSTA-AQQELRSKREQEVNILKKTLEEEAK-THEAQI---QE 1189
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAKQVDFKQKISTLRNRVKTTQKK 749
M ++ Q ++ + ++ E K +++ ++ TL+ + + + + + + +KK
Sbjct: 1190 MRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKK 1249
Query: 750 LNAHNKKLQTLYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXA 808
+ A ++LQ + + + + EL + K+Q ++ N+ Q S
Sbjct: 1250 VEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQ 1309
Query: 809 ITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ-HKK-KNV 866
+ + L+E+ K + + + + + +++ ++E +L+ +I H + ++
Sbjct: 1310 LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADM 1369
Query: 867 PREMEKIQEANDKLMEKQKQIMTDRQVLTKKID---TLKDEIAKQEV-YKRDLDDNLC-- 920
++ME + E ++++ D + L+++ + D++ K + +++LDD L
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Query: 921 --LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLII----KQTK---LFQQKAECT 971
R++ ++ QK+ D+L + I+ + E++ K+TK L + E
Sbjct: 1430 DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 972 GALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIREYAVALDK 1026
+EL++ K FR E+E +S + + ++EL +K A+++ + E L++
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSS--KDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543
Score = 44.4 bits (100), Expect = 0.002
Identities = 139/872 (15%), Positives = 338/872 (38%), Gaps = 73/872 (8%)
Query: 70 AKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTK 129
A+ N + + + +++ +I ++ LE R+ + A +K+ + L++ + +++ T
Sbjct: 1097 AQKNMALKKIRELESQISELQE-DLESERASRNKAEKQKRDLGEELEALKTELED---TL 1152
Query: 130 DVSSRCADLDILMHEELGVSKAILNSVVFCHQED-SSWPLDEGKKVKERFDEIFDADKYS 188
D ++ +L +E+ + K L H+ + V+E +++ +
Sbjct: 1153 DSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVK 1212
Query: 189 DCLDRLKKI----RKDYAQNLKLLENYATTVKAKQKELEDSYKK-NTSFNKEEE---KIA 240
L++ K+ R + A +K+L + K+K++E ++ FN+ E ++A
Sbjct: 1213 ANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELA 1272
Query: 241 NEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENAT-KTI 299
++ + ++E + L SQ+ K K + +A +++++ E+ E + + T
Sbjct: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDF--SALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 300 LEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXD 359
L++VE K+ + Q +EEE+ + + H Q
Sbjct: 1331 LKQVEDEKNSFR---EQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVK 1387
Query: 360 ITSANQSXXXXXXXXXXXXXXXXXHK-QAENELNIEECQQEINEDEKAVEQYEQEMDELS 418
K + + +++ +++ ++ E++ +
Sbjct: 1388 RKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFD 1447
Query: 419 QKITKLQKQTAKL-KEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINK 477
Q + + + +AK +E++ E + KE + + L AL E + E + +NK
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEAREKETKALSLAR----ALEEAMEQKAELE---RLNK 1500
Query: 478 FECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-P 536
+ R E+ LE ++ + + + E +++L + ED++ +
Sbjct: 1501 ---QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLR 1557
Query: 537 YDVTLSKYTTTVEK-LQ--DEQNVLQSSMFI--INKYKGQLKDN----SCCPLCNRGFEN 587
+V L E+ LQ DEQ+ + + + + + +L+D S + E
Sbjct: 1558 LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEM 1617
Query: 588 ESEXXXXXXXXXXXXMN--------VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTL 639
+ + + + +++ +L A ++EIL+ NEK
Sbjct: 1618 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKS 1677
Query: 640 KDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI 699
+ E+ QL++ + + + + +E+ + K A + + L+ I ++
Sbjct: 1678 MEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALE---EKRRLEARIAQL 1734
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT 759
+ E ++E+ G ++E+ D + Q + L QK NA + +
Sbjct: 1735 E------EELEEEQG--NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQ 1786
Query: 760 LYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
E K K +E + K + I LE QL+ + E LK+
Sbjct: 1787 NKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
+ + + RRN + Y + + A ++K L ++++ ++ E ++ +
Sbjct: 1847 -VLLQVDDERRNAE------QYKDQADKASTRLKQLKRQLEEAEE-----EAQRANASRR 1894
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
KL + + + +++ +LK+++ + ++
Sbjct: 1895 KLQRELEDATETADAMNREVSSLKNKLRRGDL 1926
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 61.7 bits (143), Expect = 2e-08
Identities = 143/808 (17%), Positives = 330/808 (40%), Gaps = 73/808 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ S + +K R D ++ L+ + E A ++E + K+ F K
Sbjct: 1122 EELEEEIEAERASRA--KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQK 1179
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K I ++
Sbjct: 1180 MRRDLEEATLQHEATAATLR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
Query: 288 TNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXX 347
+N E + K LEK+ D Q S+ +E++ Q +++ + +
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLED---QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSR 1295
Query: 348 XXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAV 407
++ ++ +A+N L Q ++ +
Sbjct: 1296 QLDEKEAL----VSQLSRGKQAFTQQIEELKRQLEEEIKAKNAL-AHALQSSRHDCDLLR 1350
Query: 408 EQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKT-ALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E + K + A E +
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV 1410
Query: 464 GNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE--RRSEL 521
V K ++ K + ++NEV L+ ++++ + L E ++ E
Sbjct: 1411 EAVNAK--CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1468
Query: 522 TKAE----DKIYKACGTQPYDV--TLSKYTTTVEKLQDEQNVLQSSMFIINKY--KGQLK 573
T AE K ++ GT+ + + + +E L+ E LQ + + + +G +
Sbjct: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1528
Query: 574 DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN 633
+ + + + + E + GK+ ++ +L + ++ D ++ K +
Sbjct: 1529 IHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK--D 1586
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+I LK I +E +D +I++ N+ + K++ GD+ ++
Sbjct: 1587 EEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIR--------------LKKKMEGDLNEME 1632
Query: 694 RYIQEI-KTVTKKFEAVKEQCGDV-DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + G + D+++ LD A Q D K++++ + R Q ++
Sbjct: 1633 IQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIE 1692
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
L+ + A++ELL+ ++VQ + +L +KK+L++D
Sbjct: 1693 ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQ 1752
Query: 808 AITPLEVALKEKI---EAKTEVVRRNRDLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKK 863
E K+ I E +++ +D SA++ +++ + VK L + + ++
Sbjct: 1753 EARNAEEKAKKAITDAAMMAEELKKEQDT----SAHLERMKKNMEQTVKDLQLRLDEAEQ 1808
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCL 921
+ ++IQ+ ++ E + ++ ++++ + + L+ + K+ Y+ + D L
Sbjct: 1809 LALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNIL 1868
Query: 922 R------KAQTDITNWQKQDDELNEKLN 943
R K Q + ++++Q +E E+ N
Sbjct: 1869 RLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
Score = 53.2 bits (122), Expect = 5e-06
Identities = 113/608 (18%), Positives = 263/608 (43%), Gaps = 63/608 (10%)
Query: 395 ECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNK 454
+ Q ++ + + + E+ D+L + TK+Q + AK+KE E+ + +L K K
Sbjct: 892 DLQLQVQAEAEGLADAEERCDQLIK--TKIQLE-AKIKEVTERAEDEEEINAELTAKKRK 948
Query: 455 HKTALMELLGNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ EL ++ + + + + K + N+V L E+K ++E+
Sbjct: 949 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEA 1008
Query: 514 LNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLK 573
+ +L EDK+ TL+K +E+ D+ L+ S+ K + L+
Sbjct: 1009 HQQTLDDLQAEEDKVN----------TLTKAKIKLEQQVDD---LEGSLEQEKKLRMDLE 1055
Query: 574 DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN 633
R E + + M++ + +++ E L++ K+ EI +++S
Sbjct: 1056 R------AKRKLEGDLKLAQESI------MDIENEKQQLDEKLKK---KEFEISNLQS-- 1098
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
KI + I QL+K+I ++ +I+ L E +E S + E++ + + ++ +
Sbjct: 1099 -KIEDEQALGI-QLQKKIKELQARIEELEEEIEAERASRAKAEKQRS---DLSRELEEIS 1153
Query: 694 RYIQEIKTVTK-KFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNA 752
++E T + E K++ + +M D+ A + + +TLR + + +L
Sbjct: 1154 ERLEEAGGATSAQIEMNKKREAEF-QKMRRDLEEA-TLQHEATAATLRKKHADSVAELGE 1211
Query: 753 HNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPL 812
LQ + +K K K E+ + ++ D+ + E+ + + + +
Sbjct: 1212 QIDNLQRVKQKLEKEKSEM---KMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK 872
E + I T +R R E+G + ++ ++L +++ + K+ +++E+
Sbjct: 1269 EEEQQRLINDLT--AQRGRLQTESG-----EFSRQLDEKEALVSQLSRGKQA-FTQQIEE 1320
Query: 873 IQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQ 932
++ ++ ++ + + Q D L+++ +++ K +L L KA T++ W+
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAEL--QRALSKANTEVAQWR 1378
Query: 933 -KQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA-LSELKKSLKGFRNELEK 990
K + + ++ EEL E + + ++ + ++ E A + L+K+ + +NE+E
Sbjct: 1379 TKYETDAIQR-----TEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVE- 1432
Query: 991 SLSKDIEK 998
L D+E+
Sbjct: 1433 DLMLDVER 1440
Score = 47.6 bits (108), Expect = 3e-04
Identities = 39/164 (23%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQD 935
K+ K T++++ T K +KDE+AK E +++L++ + L K + D+ + +
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
Query: 936 DE----LNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
E E+ + + K ++ + E+ I + T+ + + E L+ K+ L+ +EL+K
Sbjct: 901 AEGLADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 959
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + E H T+ K++ E LD+ + + +EK
Sbjct: 960 ID-DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK 1002
Score = 33.5 bits (73), Expect = 4.7
Identities = 53/272 (19%), Positives = 116/272 (42%), Gaps = 17/272 (6%)
Query: 70 AKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKT- 128
A V R +L Q +++ + A +Q E +R + L + Q L + +++ + K
Sbjct: 1678 AMVERRANLL-QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1736
Query: 129 -KDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKY 187
D+S +++ ++ E + ++ D++ +E KK ++ + K
Sbjct: 1737 ETDISQMQGEMEDILQEARNAEEKAKKAIT-----DAAMMAEELKKEQDTSAHLERMKKN 1791
Query: 188 SDCLDRLKKIRKDYAQNLKLL--ENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
+ + ++R D A+ L L + ++A+ +ELE + N E K K
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVK-GLRKHE 1850
Query: 246 NEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVES 305
+ K + +++ K R + +V+ + A++++ + EEAE + T L K
Sbjct: 1851 RRV---KELTYQTEEDRKNILRLQDLVDKLQ-AKVKSYK--RQAEEAEEQSNTNLAKFRK 1904
Query: 306 LKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
L+ + + + +AD E + + R HT+
Sbjct: 1905 LQHELEEAEERADIAESQVNKLRVKSREVHTK 1936
>BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein.
Length = 703
Score = 61.7 bits (143), Expect = 2e-08
Identities = 81/397 (20%), Positives = 186/397 (46%), Gaps = 39/397 (9%)
Query: 617 QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
+R +K E L +++ EK +L D ++ Q +++I ++ Q LNE V +T+ + +
Sbjct: 58 ERTLKQKVENLLLEA--EKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQET 115
Query: 677 QKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK----QVDF 732
QK + D+ M + + +K K+ + +E ++ +M L+ A+ + D
Sbjct: 116 QKRCLTQN---DLKMQTQQVNTLKMSEKQLK--QENNHLMEMKMNLEKQNAELRKERQDA 170
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEK---KTKAKEELLNTQKKVQDIVNLEESKK 789
++ L+++++ Q + +++ L E+ KTK +EL ++++QD +
Sbjct: 171 DGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQD--ERDSLAA 228
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKI----EAKTEVVRRNRDLIEAGSAYIAKVE 845
QL+ A KEKI E K + R ++L E A IA +E
Sbjct: 229 QLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEK-DATIASLE 287
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ-----------KQIMTDRQVL 894
N+ + D ++K+ + +++ +QE +L +++ KQ++T+R +
Sbjct: 288 ET-NRTLTSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLK 346
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQ--KQDDELNEKLNGINKEELNE 952
T+ ++ L + + ++E KR D ++ ++ + + + + ++L +++ K ELNE
Sbjct: 347 TQAVNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQK-ELNE 405
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
++ I +++++ + E L ++ R++L+
Sbjct: 406 MQAQIAEESQI---RIELQMTLDSKDSDIEQLRSQLQ 439
Score = 37.1 bits (82), Expect = 0.38
Identities = 91/443 (20%), Positives = 194/443 (43%), Gaps = 59/443 (13%)
Query: 652 VDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
+D+ Q+K + +++E+ E E K T A+ D + I+E K+ EA+KE
Sbjct: 3 IDMTYQLKVIQQSLEQE-----EAEHKATKARL--ADKNKIYESIEEAKS-----EAMKE 50
Query: 712 QCGDVDSEMTLDVATAKQV-DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
+ E TL + + +++ S L +K +Q+K+N L ++K E+
Sbjct: 51 MEKKLLEERTLKQKVENLLLEAEKRCSLLDCDLKQSQQKINE-------LLKQKDVLNED 103
Query: 771 LLNTQKKVQDIVNLEESKKQL-QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR 829
+ N K++ E K+ L Q+D + L+ +E K + ++
Sbjct: 104 VRNLTLKIEQ----ETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQ 159
Query: 830 NRDLIEAGSAYIAKVEVAFNKVKSLD--AEIQQHKKKNVPREMEKIQEANDKLMEKQKQI 887
N +L + + + A ++K L E +Q+ ++ +++E ++ + K++
Sbjct: 160 NAELRK-------ERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLGKEL 212
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQD--DELNEK-LNG 944
+Q L + D+L ++ + + K D + L A+ ++ +K+ EL K +
Sbjct: 213 QQKKQELQDERDSLAAQL-EITLTKAD-SEQLARSIAEEQYSDLEKEKIMKELEIKEMMA 270
Query: 945 INKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
+K+EL EK++ I L + T ++ L + N+L KD++++ ++
Sbjct: 271 RHKQELTEKDATI---ASLEETNRTLTSDVANLANEKEELNNKL-----KDVQEQL-SRL 321
Query: 1005 YELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRK--IYRGNDIDYIEIK 1062
+ ++ A K +K L+ K + +N + + RK + RGND D +
Sbjct: 322 KDEEISAAAIK------AQFEKQLLTERTLKTQAVNKLAEIMNRKEPVKRGNDTDVRRKE 375
Query: 1063 TEG---NLTVESERRKYDYRVVQ 1082
E ++ ++SER K ++++
Sbjct: 376 KENRKLHMELKSEREKLTQQMIK 398
Score = 36.3 bits (80), Expect = 0.66
Identities = 61/334 (18%), Positives = 135/334 (40%), Gaps = 26/334 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL-KEKEMIEENLKTKEK 446
+N+L ++ Q++N + + +Q +QE + L + L+KQ A+L KE++ + +K +
Sbjct: 122 QNDLKMQT--QQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQD 179
Query: 447 QLIV---LKNKHKTALMELLGNVPEK-DFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
QL +KT + EL EK + + + E+++E
Sbjct: 180 QLEAEQYFSTLYKTQVRELKEECEEKTKLGKELQQKKQELQDERDSLAAQLEITLTKADS 239
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
+ R E ++ E E +I + ++T + T+ L++ L S +
Sbjct: 240 EQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELT--EKDATIASLEETNRTLTSDV 297
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEK--VTEDLQRAS 620
+ K +L N ++ E + + EK +TE +
Sbjct: 298 ANLANEKEEL---------NNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQ 348
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT----LNETVEEITMSLIEPE 676
A +++ + + E + DT++ + EK + ++K+ L + + + L E +
Sbjct: 349 A-VNKLAEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQ 407
Query: 677 QKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAV 709
++ QI ++ M LD +I+ + + +A+
Sbjct: 408 AQIAEESQIRIELQMTLDSKDSDIEQLRSQLQAL 441
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 61.7 bits (143), Expect = 2e-08
Identities = 143/808 (17%), Positives = 330/808 (40%), Gaps = 73/808 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ S + +K R D ++ L+ + E A ++E + K+ F K
Sbjct: 1122 EELEEEIEAERASRA--KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQK 1179
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K I ++
Sbjct: 1180 MRRDLEEATLQHEATAATLR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 1238
Query: 288 TNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXX 347
+N E + K LEK+ D Q S+ +E++ Q +++ + +
Sbjct: 1239 SNVETVSKAKGNLEKMCRTLED---QLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSR 1295
Query: 348 XXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAV 407
++ ++ +A+N L Q ++ +
Sbjct: 1296 QLDEKEAL----VSQLSRGKQAFTQQIEELKRQLEEEIKAKNAL-AHALQSSRHDCDLLR 1350
Query: 408 EQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKT-ALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E + K + A E +
Sbjct: 1351 EQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHV 1410
Query: 464 GNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE--RRSEL 521
V K ++ K + ++NEV L+ ++++ + L E ++ E
Sbjct: 1411 EAVNAK--CASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEE 1468
Query: 522 TKAE----DKIYKACGTQPYDV--TLSKYTTTVEKLQDEQNVLQSSMFIINKY--KGQLK 573
T AE K ++ GT+ + + + +E L+ E LQ + + + +G +
Sbjct: 1469 THAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKR 1528
Query: 574 DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN 633
+ + + + + E + GK+ ++ +L + ++ D ++ K +
Sbjct: 1529 IHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK--D 1586
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+I LK I +E +D +I++ N+ + K++ GD+ ++
Sbjct: 1587 EEIDQLKRNHIRIVESMQSTLDAEIRSRNDAIR--------------LKKKMEGDLNEME 1632
Query: 694 RYIQEI-KTVTKKFEAVKEQCGDV-DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + G + D+++ LD A Q D K++++ + R Q ++
Sbjct: 1633 IQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIE 1692
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
L+ + A++ELL+ ++VQ + +L +KK+L++D
Sbjct: 1693 ELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQ 1752
Query: 808 AITPLEVALKEKI---EAKTEVVRRNRDLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKK 863
E K+ I E +++ +D SA++ +++ + VK L + + ++
Sbjct: 1753 EARNAEEKAKKAITDAAMMAEELKKEQDT----SAHLERMKKNMEQTVKDLQLRLDEAEQ 1808
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLK--DEIAKQEVYKRDLDDNLCL 921
+ ++IQ+ ++ E + ++ ++++ + + L+ + K+ Y+ + D L
Sbjct: 1809 LALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNIL 1868
Query: 922 R------KAQTDITNWQKQDDELNEKLN 943
R K Q + ++++Q +E E+ N
Sbjct: 1869 RLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
Score = 53.2 bits (122), Expect = 5e-06
Identities = 113/608 (18%), Positives = 263/608 (43%), Gaps = 63/608 (10%)
Query: 395 ECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNK 454
+ Q ++ + + + E+ D+L + TK+Q + AK+KE E+ + +L K K
Sbjct: 892 DLQLQVQAEAEGLADAEERCDQLIK--TKIQLE-AKIKEVTERAEDEEEINAELTAKKRK 948
Query: 455 HKTALMELLGNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ EL ++ + + + + K + N+V L E+K ++E+
Sbjct: 949 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEA 1008
Query: 514 LNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLK 573
+ +L EDK+ TL+K +E+ D+ L+ S+ K + L+
Sbjct: 1009 HQQTLDDLQAEEDKVN----------TLTKAKIKLEQQVDD---LEGSLEQEKKLRMDLE 1055
Query: 574 DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN 633
R E + + M++ + +++ E L++ K+ EI +++S
Sbjct: 1056 R------AKRKLEGDLKLAQESI------MDIENEKQQLDEKLKK---KEFEISNLQS-- 1098
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
KI + I QL+K+I ++ +I+ L E +E S + E++ + + ++ +
Sbjct: 1099 -KIEDEQALGI-QLQKKIKELQARIEELEEEIEAERASRAKAEKQRS---DLSRELEEIS 1153
Query: 694 RYIQEIKTVTK-KFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNA 752
++E T + E K++ + +M D+ A + + +TLR + + +L
Sbjct: 1154 ERLEEAGGATSAQIEMNKKREAEF-QKMRRDLEEA-TLQHEATAATLRKKHADSVAELGE 1211
Query: 753 HNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPL 812
LQ + +K K K E+ + ++ D+ + E+ + + + +
Sbjct: 1212 QIDNLQRVKQKLEKEKSEM---KMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK 872
E + I T +R R E+G + ++ ++L +++ + K+ +++E+
Sbjct: 1269 EEEQQRLINDLT--AQRGRLQTESG-----EFSRQLDEKEALVSQLSRGKQA-FTQQIEE 1320
Query: 873 IQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQ 932
++ ++ ++ + + Q D L+++ +++ K +L L KA T++ W+
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAEL--QRALSKANTEVAQWR 1378
Query: 933 -KQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA-LSELKKSLKGFRNELEK 990
K + + ++ EEL E + + ++ + ++ E A + L+K+ + +NE+E
Sbjct: 1379 TKYETDAIQR-----TEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVE- 1432
Query: 991 SLSKDIEK 998
L D+E+
Sbjct: 1433 DLMLDVER 1440
Score = 47.6 bits (108), Expect = 3e-04
Identities = 39/164 (23%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQD 935
K+ K T++++ T K +KDE+AK E +++L++ + L K + D+ + +
Sbjct: 841 KIKPLLKSAETEKEMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAE 900
Query: 936 DE----LNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
E E+ + + K ++ + E+ I + T+ + + E L+ K+ L+ +EL+K
Sbjct: 901 AEGLADAEERCDQLIKTKI-QLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKD 959
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + E H T+ K++ E LD+ + + +EK
Sbjct: 960 ID-DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEK 1002
Score = 33.5 bits (73), Expect = 4.7
Identities = 53/272 (19%), Positives = 116/272 (42%), Gaps = 17/272 (6%)
Query: 70 AKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKT- 128
A V R +L Q +++ + A +Q E +R + L + Q L + +++ + K
Sbjct: 1678 AMVERRANLL-QAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKL 1736
Query: 129 -KDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKY 187
D+S +++ ++ E + ++ D++ +E KK ++ + K
Sbjct: 1737 ETDISQMQGEMEDILQEARNAEEKAKKAIT-----DAAMMAEELKKEQDTSAHLERMKKN 1791
Query: 188 SDCLDRLKKIRKDYAQNLKLL--ENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
+ + ++R D A+ L L + ++A+ +ELE + N E K K
Sbjct: 1792 MEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNAEAVK-GLRKHE 1850
Query: 246 NEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVES 305
+ K + +++ K R + +V+ + A++++ + EEAE + T L K
Sbjct: 1851 RRV---KELTYQTEEDRKNILRLQDLVDKLQ-AKVKSYK--RQAEEAEEQSNTNLAKFRK 1904
Query: 306 LKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
L+ + + + +AD E + + R HT+
Sbjct: 1905 LQHELEEAEERADIAESQVNKLRVKSREVHTK 1936
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 61.7 bits (143), Expect = 2e-08
Identities = 115/637 (18%), Positives = 263/637 (41%), Gaps = 51/637 (8%)
Query: 384 HKQAEN---ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-K 432
H QAE + NI+E ++++ E+E A ++ + E K+ KL++ Q KL K
Sbjct: 933 HLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAK 992
Query: 433 EKEMIEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEV 482
EK+++E+ + + K K L LKNKH+ + +L + ++ K E+
Sbjct: 993 EKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE------KQRQEL 1046
Query: 483 RNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS 542
L+A+ ++ L ++ EL A ++ + + ++ L
Sbjct: 1047 EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK--NMALK 1104
Query: 543 KYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD-NSCCPLCNRGFENESEXXXXXXXXXXX 601
K ++ + Q L+S NK + Q +D E+ +
Sbjct: 1105 KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSK 1164
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL 661
L+K E + A + +I M+ + + ++ Q ++ +++ +TL
Sbjct: 1165 REQEVNILKKTLE--EEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 662 ----NETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTV-TKKFEAVKEQCGDV 716
E E+ + L K++ + L E + V T+ + V + ++
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 717 DSEM-TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
D+ L + +K + S L ++++ TQ+ L N++ +L K + ++E + +
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFR 1342
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
+++++ EE+K L+ + L+ E K ++ +DL
Sbjct: 1343 EQLEE---EEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL---QKDLEG 1396
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQK---QIMTDRQ 892
+ KV A++K++ +QQ + ++ +++ +++ L +KQK Q++ + +
Sbjct: 1397 LSQRHEEKV-AAYDKLEKTKTRLQQ-ELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
++ K +D A+ E +++ L L +A + + + + LN++ ++ ++
Sbjct: 1455 TISAKYAEERDR-AEAEAREKE-TKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSS 1512
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
K+ + +L + K + E+K L+ +EL+
Sbjct: 1513 KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQ 1549
Score = 60.1 bits (139), Expect = 5e-08
Identities = 152/743 (20%), Positives = 305/743 (41%), Gaps = 78/743 (10%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
E L EE Q++ E EK + E + +LS +I +LQ Q A+LK + L KE++
Sbjct: 1033 EERLRREEKQRQ--ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQ------LAKKEEE 1084
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
L + AL + +K+ A + K E+ +++ E ++
Sbjct: 1085 L-------QAALARVEEEAAQKNMA--LKKIR-ELESQISELQEDLESERASRNKAEKQK 1134
Query: 508 KHIRESLNERRSELTKAEDKI---YKACGTQPYDVTLSKYTTTVEKLQDE---QNVLQSS 561
+ + E L ++EL D + + +V + K T E E Q + Q
Sbjct: 1135 RDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH 1194
Query: 562 MFIINKYKGQLKDNSCCPL----CNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + QL+ + ENE E + K +KV L
Sbjct: 1195 SQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQL 1254
Query: 617 QRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
Q K +E +++ L +K+T L+ E+ + + D++ L + + L +
Sbjct: 1255 QELQVKFNEGERVRTELADKVTKLQ-VELDNVTGLLSQSDSKSSKLTKDFSALESQLQDT 1313
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT--AKQVDFK 733
++ + ++ + L +++++ F E+ + + +AT A+ D K
Sbjct: 1314 QELL---QEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMK 1370
Query: 734 QKISTLRNRVKTTQ---KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN--LEESK 788
+K+ ++T + +KL + L +E+K A ++L T+ ++Q ++ L +
Sbjct: 1371 KKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLD 1430
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
Q QS C ++ +EK + R+R EA + +A
Sbjct: 1431 HQRQSACNLEKKQKKFD-------QLLAEEKTISAKYAEERDRAEAEAREKETKALSLAR 1483
Query: 849 NKVKSLDAEIQQHK-KKNVPREMEKIQEANDKL------MEKQKQIMTDR-QVLTKKIDT 900
++++ + + + K EME + + D + +EK K+ + + + + +++
Sbjct: 1484 ALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
L+DE+ E K L+ NL KAQ + + Q +D++ EK + + ++ E E+ + +
Sbjct: 1544 LEDELQATEDAKLRLEVNLQAMKAQFE-RDLQGRDEQSEEKKKQLVR-QVREMEAELEDE 1601
Query: 961 TKLFQQKAECTGALSELKKSLKGF----------RNELEKSLSKDIEKKFREKMYELHVT 1010
K Q++ A +L+ LK R+E K L K ++ + ++ M EL T
Sbjct: 1602 RK---QRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK-LQAQMKDCMRELDDT 1657
Query: 1011 KAIDKDIREYAVALDKCL--MEFHREKMENINMIIRELWRKIYRGNDIDYIEIKT---EG 1065
+A ++I A +K L ME +++ R+ + D EI +G
Sbjct: 1658 RASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKG 1717
Query: 1066 NLTVESERRKYDYRVVQSKNGVE 1088
L +E E+R+ + R+ Q + +E
Sbjct: 1718 ALALE-EKRRLEARIAQLEEELE 1739
Score = 54.8 bits (126), Expect = 2e-06
Identities = 119/656 (18%), Positives = 271/656 (41%), Gaps = 46/656 (7%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN 453
+E ++ ++ E VE+ E+ L + K+Q+ +L E+++ EE ++ QL +
Sbjct: 911 QELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQEL-EEQLEEEESARQKLQLEKVTT 969
Query: 454 KHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ K +E + + + C++ E E + K + +
Sbjct: 970 EAKLKKLE--------EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKL 1021
Query: 514 LNERRSELTKAEDKIYK-ACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQL 572
N+ + +T E+++ + Q + T K L D+ LQ+ I + K QL
Sbjct: 1022 KNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQ---IAELKMQL 1078
Query: 573 KDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL--QRASAKKDEILSMK 630
E + ++ ++ EDL +RAS K E +
Sbjct: 1079 AKKE--EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAE-KQKR 1135
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMP 690
L E++ LK TE+ ++++ E I +E E K T QI
Sbjct: 1136 DLGEELEALK-TELEDTLDSTA-AQQELRSKREQEVNILKKTLEEEAK-THEAQI---QE 1189
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAKQVDFKQKISTLRNRVKTTQKK 749
M ++ Q ++ + ++ E K +++ ++ TL+ + + + + + + +KK
Sbjct: 1190 MRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKK 1249
Query: 750 LNAHNKKLQTLYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXA 808
+ A ++LQ + + + + EL + K+Q ++ N+ Q S
Sbjct: 1250 VEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQ 1309
Query: 809 ITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ-HKK-KNV 866
+ + L+E+ K + + + + + +++ ++E +L+ +I H + ++
Sbjct: 1310 LQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADM 1369
Query: 867 PREMEKIQEANDKLMEKQKQIMTDRQVLTKKID---TLKDEIAKQEV-YKRDLDDNLC-- 920
++ME + E ++++ D + L+++ + D++ K + +++LDD L
Sbjct: 1370 KKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Query: 921 --LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLII----KQTK---LFQQKAECT 971
R++ ++ QK+ D+L + I+ + E++ K+TK L + E
Sbjct: 1430 DHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 1489
Query: 972 GALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIREYAVALDK 1026
+EL++ K FR E+E +S + + ++EL +K A+++ + E L++
Sbjct: 1490 EQKAELERLNKQFRTEMEDLMSS--KDDVGKSVHELEKSKRALEQQVEEMKTQLEE 1543
Score = 44.4 bits (100), Expect = 0.002
Identities = 139/872 (15%), Positives = 338/872 (38%), Gaps = 73/872 (8%)
Query: 70 AKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTK 129
A+ N + + + +++ +I ++ LE R+ + A +K+ + L++ + +++ T
Sbjct: 1097 AQKNMALKKIRELESQISELQE-DLESERASRNKAEKQKRDLGEELEALKTELED---TL 1152
Query: 130 DVSSRCADLDILMHEELGVSKAILNSVVFCHQED-SSWPLDEGKKVKERFDEIFDADKYS 188
D ++ +L +E+ + K L H+ + V+E +++ +
Sbjct: 1153 DSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVK 1212
Query: 189 DCLDRLKKI----RKDYAQNLKLLENYATTVKAKQKELEDSYKK-NTSFNKEEE---KIA 240
L++ K+ R + A +K+L + K+K++E ++ FN+ E ++A
Sbjct: 1213 ANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELA 1272
Query: 241 NEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENAT-KTI 299
++ + ++E + L SQ+ K K + +A +++++ E+ E + + T
Sbjct: 1273 DKVTKLQVELDNVTGLLSQSDSKSSKLTKDF--SALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 300 LEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXD 359
L++VE K+ + Q +EEE+ + + H Q
Sbjct: 1331 LKQVEDEKNSFR---EQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVK 1387
Query: 360 ITSANQSXXXXXXXXXXXXXXXXXHK-QAENELNIEECQQEINEDEKAVEQYEQEMDELS 418
K + + +++ +++ ++ E++ +
Sbjct: 1388 RKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFD 1447
Query: 419 QKITKLQKQTAKL-KEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINK 477
Q + + + +AK +E++ E + KE + + L AL E + E + +NK
Sbjct: 1448 QLLAEEKTISAKYAEERDRAEAEAREKETKALSLAR----ALEEAMEQKAELE---RLNK 1500
Query: 478 FECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-P 536
+ R E+ LE ++ + + + E +++L + ED++ +
Sbjct: 1501 ---QFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLR 1557
Query: 537 YDVTLSKYTTTVEK-LQ--DEQNVLQSSMFI--INKYKGQLKDN----SCCPLCNRGFEN 587
+V L E+ LQ DEQ+ + + + + + +L+D S + E
Sbjct: 1558 LEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEM 1617
Query: 588 ESEXXXXXXXXXXXXMN--------VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTL 639
+ + + + +++ +L A ++EIL+ NEK
Sbjct: 1618 DLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKS 1677
Query: 640 KDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI 699
+ E+ QL++ + + + + +E+ + K A + + L+ I ++
Sbjct: 1678 MEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALE---EKRRLEARIAQL 1734
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT 759
+ E ++E+ G ++E+ D + Q + L QK NA + +
Sbjct: 1735 E------EELEEEQG--NTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQ 1786
Query: 760 LYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
E K K +E + K + I LE QL+ + E LK+
Sbjct: 1787 NKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKD 1846
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
+ + + RRN + Y + + A ++K L ++++ ++ E ++ +
Sbjct: 1847 -VLLQVDDERRNAE------QYKDQADKASTRLKQLKRQLEEAEE-----EAQRANASRR 1894
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
KL + + + +++ +LK+++ + ++
Sbjct: 1895 KLQRELEDATETADAMNREVSSLKNKLRRGDL 1926
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 61.3 bits (142), Expect = 2e-08
Identities = 186/963 (19%), Positives = 385/963 (39%), Gaps = 105/963 (10%)
Query: 101 KVTALAKKKTKF-QTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFC 159
KV L K KTK Q +D ++++ K + DL+ + G K S +
Sbjct: 1019 KVNILTKAKTKLEQQVDDLEGSLEQEKKLR------MDLERAKRKLEGDLKLAQESTM-- 1070
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQ 219
E+ LDE K K+ F+ K D +++K + +E ++A++
Sbjct: 1071 DMENDKQQLDE-KLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAER 1129
Query: 220 KELEDSYKKNTSFNKEEEKI------ANEKSSNEIEYNKFILLESQ----NQEKIDKRNE 269
+ K+ + ++E E+I A +S ++E NK E Q + E+ ++E
Sbjct: 1130 ASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHE 1189
Query: 270 QIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQK---SQADEEEKKAQG 326
+V + +++ E+ E+ +N + + +K+E KS+ K++ S E KA+G
Sbjct: 1190 AMVAALRKKHADSMAEL--GEQIDNLQR-VKQKLEKEKSELKMETDDLSSNAEAISKAKG 1246
Query: 327 FVDE-CRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXX--XX 383
+++ CRS Q ++
Sbjct: 1247 NLEKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSR 1306
Query: 384 HKQAENELNIEECQQEINEDEKAV------------------EQYEQEMD---ELSQKIT 422
KQA + IEE + ++ E+ KA EQYE+E + EL + ++
Sbjct: 1307 SKQASTQ-QIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1365
Query: 423 KLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDF-AVTINKFECE 481
K + A+ + K + +T+E L K K L E +V + ++ K +
Sbjct: 1366 KANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQR 1423
Query: 482 VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE--RRSELTKAEDKIYKACGTQPYDV 539
++NEV L+ ++++ + L+E ++ E T+AE + + ++
Sbjct: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQK-ESRSLST 1482
Query: 540 TLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXX 599
L K E+ D+ L+ + + L + G + E
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA-----EGGKQIHELEKIKKQVE 1537
Query: 600 XXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD 655
+ LE+ L+ K + E+ +KS ++ KD EI QL++ V
Sbjct: 1538 QEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRV- 1596
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCG 714
++T+ T++ S + K++ GD+ ++ + + + + G
Sbjct: 1597 --VETMQSTLDAEIRSR---NDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQG 1651
Query: 715 DV-DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLN 773
+ ++++ LD A Q D K++++ + R Q ++ L+ + A++ELL+
Sbjct: 1652 ILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLD 1711
Query: 774 TQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRR 829
++VQ + +L +KK+L++D ++ L+ ++E I+ +
Sbjct: 1712 ASERVQLLHTQNTSLINTKKKLEND--------------VSQLQSEVEEVIQESRNAEEK 1757
Query: 830 NRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLME-KQKQIM 888
+ I +A +A+ K + A +++ KKN+ + ++ +Q D+ + K
Sbjct: 1758 AKKAI-TDAAMMAE---ELKKEQDTSAHLER-MKKNLEQTVKDLQHRLDEAEQLALKGGK 1812
Query: 889 TDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE 948
Q L ++ L+ E+ ++ KR+ + LRK + + Q +E ++ N + +
Sbjct: 1813 KQIQKLEARVRELEGEVENEQ--KRNAEAVKGLRKHERRVKELTYQTEE--DRKNVLRLQ 1868
Query: 949 ELNEKESLIIKQTKLFQQKAE--CTGALSELKKSLKGFRNELEKS-LSKDIEKKFREKMY 1005
+L +K +K K ++AE LS+ +K E++ +++ K R K
Sbjct: 1869 DLVDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERAHIAESQVNKLRVKSR 1928
Query: 1006 ELH 1008
E+H
Sbjct: 1929 EVH 1931
Score = 53.2 bits (122), Expect = 5e-06
Identities = 114/700 (16%), Positives = 281/700 (40%), Gaps = 44/700 (6%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIE-ENLKT 443
K AE E + ++E + + + + E + EL +K+ L K+ L+ + E ++L
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903
Query: 444 KEK---QLIVLKNKHKTALMELLGNVPEKD-FAVTINKFECEVRNEVXXXXXXXXXXXXX 499
E+ QLI K + + + E+ E++ + + ++ +E
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E+ + E+ ++ I K ++ + T++ LQ E++ +
Sbjct: 964 LAKVEKEKHATENKVKNLTEEMAGLDETIAKL--SKEKKALQETHQQTLDDLQAEEDKVN 1021
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
I+ K K +L+ E E + ++ T D++
Sbjct: 1022 ----ILTKAKTKLEQQ--VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMEND 1075
Query: 620 SAKKDEILSMKS--LNEKITTLKDTEIP--QLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
+ DE L K ++ I+ ++D + QL+K+I ++ +I+ L E +E S +
Sbjct: 1076 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 1135
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK 735
E++ + + ++ + ++E T + ++ ++ D+ A + +
Sbjct: 1136 EKQRS---DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA-TLQHEAM 1191
Query: 736 ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEESKKQLQSD 794
++ LR + + +L LQ + +K K K EL + T + + ++K L+
Sbjct: 1192 VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKM 1251
Query: 795 CXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSL 854
C ++ L+ +E+ ++ + L Y +++ + +L
Sbjct: 1252 C-------RSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLD----EKDAL 1300
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
+++ + K+ + +++E+++ ++ + + + Q D L+++ +++ K +
Sbjct: 1301 VSQLSRSKQAST-QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAE 1359
Query: 915 LDDNLCLRKAQTDITNWQ-KQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA 973
L L KA +++ W+ K + + ++ EEL E + + ++ + ++ E A
Sbjct: 1360 L--QRALSKANSEVAQWRTKYETDAIQR-----TEELEEAKKKLAQRLQEAEEHVEAVNA 1412
Query: 974 -LSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ L+K+ + +NE+E L D+E+ + DK + E+ ++ E
Sbjct: 1413 KCASLEKTKQRLQNEVE-DLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELE 1471
Query: 1033 REKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESE 1072
+ E+ ++ K +D +E N ++ E
Sbjct: 1472 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQE 1511
Score = 50.0 bits (114), Expect = 5e-05
Identities = 41/164 (25%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDI-TNWQKQ 934
K+ K T++++ T K KDE+AK E +++L++ + L K + D+ Q +
Sbjct: 838 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 897
Query: 935 DDEL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
D L E+ + K ++ + E+ I + T+ +++ E L+ K+ L+ +EL+K
Sbjct: 898 ADSLADAEERCEQLIKNKI-QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKD 956
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + E H T+ K++ E LD+ + + +EK
Sbjct: 957 ID-DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEK 999
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 61.3 bits (142), Expect = 2e-08
Identities = 125/639 (19%), Positives = 262/639 (41%), Gaps = 50/639 (7%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEM-IEENLKTKEKQLIVL 451
+E E E + ++E+ +L + I KL+ + ++K++ I E LK +E++ L
Sbjct: 2092 LEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSL 2151
Query: 452 KNKHKTALMELLGNVPEKDFAVTI---NKFECE-VRNEVXXXXXXXXXXXXXXXXLEAER 507
K+K + EL + ++ + +K E E ++ ++ L +E+
Sbjct: 2152 KDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK 2211
Query: 508 KHIRESLNERRSELTKAEDKI--YKACGTQPYDVTLS---KYTTTVEKLQDEQNVLQSSM 562
+++ + + E++ +L++ + + +K+ + + + T VE LQ++ L ++
Sbjct: 2212 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2271
Query: 563 FIINKYKGQLK--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS 620
+ + +K + S P + + L+++ E A
Sbjct: 2272 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD 2331
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMT 680
K + +++ E T ++ + E +++TL +E +T SL E +
Sbjct: 2332 LLKGRVENLERELEIARTNQEHAALEAENS----KGEVETLKAKIEGMTQSLRGLELDVV 2387
Query: 681 TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLR 740
T I + L +Q+ + + E + ++ L ++V K+K ST
Sbjct: 2388 T---IRSEKENLTNELQKEQERISELEIINSSFENI-----LQEKEQEKVQMKEKSSTAM 2439
Query: 741 NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXX 800
++T K+LN L E KAKE+ L++Q + LE K QL
Sbjct: 2440 EMLQTQLKELNERVAALHNDQEA-CKAKEQNLSSQVEC-----LELEKAQLLQGLDEAKN 2493
Query: 801 XXXXXXXAITPLEVAL---KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
++ L + K+K+E K E + R ++ I+ E +K+ ++ E
Sbjct: 2494 NYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQ-------DQEQLVSKLSQVEGE 2546
Query: 858 IQQHKKKNVP-REME-KIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
Q K++N+ R + ++++ L K + +VL L++E+ ++ K
Sbjct: 2547 HQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSF 2606
Query: 916 DDNLCLRKA-----QTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ-QKAE 969
+ + A Q ++ ++ EL E+L+G K L + L++++ K + Q E
Sbjct: 2607 VEKVNKMTAKETELQREMHEMAQKTAELQEELSG-EKNRLAGELQLLLEEIKSSKDQLKE 2665
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
T SELKKSL + + K + ++ E LH
Sbjct: 2666 LTLENSELKKSLDCMHKDQVEKEGK-VREEIAEYQLRLH 2703
Score = 55.6 bits (128), Expect = 1e-06
Identities = 140/764 (18%), Positives = 312/764 (40%), Gaps = 89/764 (11%)
Query: 181 IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIA 240
I DA+ ++ LK ++ A++LK+ E T++++++ L ++ E +K+
Sbjct: 2173 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLL 2232
Query: 241 NE-KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK-IAEIENITEVQTNEEAENATKT 298
+ KS E + I ++ +++ ++ Q+ E + +A + E+ + E +
Sbjct: 2233 SSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIM--KATEQSLDP 2290
Query: 299 ILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXX 358
+E+ L++ + +++ + +EKK + + +
Sbjct: 2291 PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL------ 2344
Query: 359 DITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELS 418
+I NQ K IE Q + E V E + L+
Sbjct: 2345 EIARTNQEHAALEAENSKGEVETLKAK-------IEGMTQSLRGLELDVVTIRSEKENLT 2397
Query: 419 QKITKLQKQTAKLKEKEMIEEN-LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINK 477
++ K Q++ ++L+ EN L+ KE++ + +K K TA+ L + E +N+
Sbjct: 2398 NELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKE------LNE 2451
Query: 478 FECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPY 537
+ N+ LE E+ + + L+E ++ Y
Sbjct: 2452 RVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNN----------------Y 2495
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
V S +++++D + L+ I++ K Q++D L ++ + E E
Sbjct: 2496 IVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQE--QLVSKLSQVEGEHQLWKEQ 2553
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEIL-----SMKSLNEKITTLKDTEIPQLEKRIV 652
N+ +LE+ + LQ +A + L S K+L ++ K ++ +EK +
Sbjct: 2554 NLELR-NLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VN 2611
Query: 653 DVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
+ + L + E+ E +++++ K ++ G++ +L ++EIK+ + + +
Sbjct: 2612 KMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLL---LEEIKSSKDQLKELTL 2668
Query: 712 QCGDVDSEMTLDVATAKQVD----FKQKISTLRNRVKTTQKKLNA----HNKKLQT---L 760
+ ++ + +LD QV+ +++I+ + R+ +KK A NK+ +
Sbjct: 2669 ENSEL--KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQT 2726
Query: 761 YEKKTKAKEELLNTQKKVQDIVN----------------LEESKKQLQSDCXXXXXXXXX 804
Y +K +KEE L++QK D++ LEE KK +
Sbjct: 2727 YREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKE 2786
Query: 805 XXXAITPLEVALK--EKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK 862
A +++ +K +++E + E++++ ++A V KV L EI++ K
Sbjct: 2787 NERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELK 2846
Query: 863 KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
+ EK +EA D+ ++K ++ + L K + L+ ++A
Sbjct: 2847 E----TLEEKTKEA-DEYLDKYCSLLISHEKLEKAKEMLETQVA 2885
Score = 54.0 bits (124), Expect = 3e-06
Identities = 116/632 (18%), Positives = 264/632 (41%), Gaps = 47/632 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK--QTAKLKEKEMIEENLK 442
+QA+N N+ Q E+++ +Q E ++E QK+ + ++ Q +++KE E+ +++
Sbjct: 426 QQAKNMHNV--LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL-RRSME 482
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
+K+ +LK+ + E+ E K+ +N+ + N
Sbjct: 483 EMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ----NFAEEMKAKNTSQETMLR 538
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGT---QPYDVTLSKYTTTVEKLQDEQNVL 558
L+ + SL + +L A+ + + C + + + + + K + E L
Sbjct: 539 DLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Query: 559 QSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
S++ + K + +LK+ C + ENE N+ K+ + L+
Sbjct: 599 LSALEL-KKKEYELKEEKTLFSCWKS-ENEK----LLTQMESEKENLQSKINHLETCLKT 652
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
K E NE++ TL + + L I ++ + + + VE ++ +E +QK
Sbjct: 653 QQIKSHEY------NERVRTL-EMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQK 705
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q H ++ + +T + E ++ + + +E+ +D Q D + +
Sbjct: 706 AEFSDQKH--QKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI-MDKDRCYQ-DLHAEYES 761
Query: 739 LRNRVKTTQKKL--NAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCX 796
LR+ +K+ L N +++ ++++ N + Q + E S+ +L++D
Sbjct: 762 LRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGE-QGSMPSERSECRLEAD-- 818
Query: 797 XXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDA 856
+ LE +L+ + + +++ ++ +L++ + A +S A
Sbjct: 819 QSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVA 878
Query: 857 EIQQHKKK---NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
E Q K + + E L K+K++ Q+L K++T + EI + +
Sbjct: 879 ETSQRISKLQEDTSAHQNVVAETLSALENKEKEL----QLLNDKVETEQAEIQELKKSNH 934
Query: 914 DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAECTG 972
L+D+L + ++ + +K++ LN EEL ++ + + L Q+K
Sbjct: 935 LLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN--- 991
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
L + +S + +E EKS+S+ ++ +EK+
Sbjct: 992 -LIQKSESFANYIDEREKSISELSDQYKQEKL 1022
Score = 49.6 bits (113), Expect = 7e-05
Identities = 92/463 (19%), Positives = 215/463 (46%), Gaps = 59/463 (12%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTL-KDTEIP-----QLEKRIVDVDTQIKT 660
++++ TE LQ S+ E+L K+ L EK+ +L KD++ +LE +I ++ + +
Sbjct: 2007 EVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKEL 2066
Query: 661 LNETVEEITMSLIEPE-QKMTTAKQIH------GDMPM-LDRYIQEIKTVTKKFEAVKEQ 712
L + E + L E + +K+ +K + G+ + L +E+ + + E ++ +
Sbjct: 2067 LVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVR 2126
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL--NAHNKKLQTLYEKKTKAKEE 770
+ D + L +A K + +++ +L+++V+ +++L + N++L L + +KA+ E
Sbjct: 2127 I-EADEKKQLHIAE-KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVE 2184
Query: 771 LLNTQKKVQ---------DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE 821
L TQ + D+V L K+ L ++ + L+EK +
Sbjct: 2185 TLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQ 2244
Query: 822 AKTEVVRRN-----------RDLIEAGSAYIAKVEVAFNKVKSLDAEI-QQHKKKNVPRE 869
A+ ++ + ++L EA +A E+ +SLD I ++H+ +N +
Sbjct: 2245 AEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2304
Query: 870 MEKIQEANDK----LMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD-NLCLRKA 924
+ EA++K ++++ K+ +L +++ L+ E+ E+ + + + L +
Sbjct: 2305 LRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL---EIARTNQEHAALEAENS 2361
Query: 925 QTDITNWQKQDDELNEKLNGINKEEL---NEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ ++ + + + + + L G+ + + +EKE+L T Q++ E +SEL+
Sbjct: 2362 KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENL----TNELQKEQE---RISELEIIN 2414
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVAL 1024
F N L++ + ++ K + + + + K++ E AL
Sbjct: 2415 SSFENILQEKEQEKVQMK-EKSSTAMEMLQTQLKELNERVAAL 2456
Score = 46.4 bits (105), Expect = 6e-04
Identities = 98/470 (20%), Positives = 197/470 (41%), Gaps = 46/470 (9%)
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K + ++ ++ ++ QLEK V++ + K LN+ +E+ + + +Q T + +
Sbjct: 306 KEMKGQVNKFQELQL-QLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKL 364
Query: 690 PMLDRYI----QEIKTVTKKFE-AVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK 744
L + Q ++ E +KE+ + E++ + + +D ++ I +
Sbjct: 365 KKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLD-QECIQMKARLTQ 423
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q+ N HN LQ +K T K++L N NLEE K++L
Sbjct: 424 ELQQAKNMHN-VLQAELDKLTSVKQQLEN---------NLEEFKQKLCRAEQAFQASQIK 473
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
+E KE K+ ++ R++ A + ++ N+ ++ E+ K K
Sbjct: 474 ENELRRSMEEMKKENNLLKSHSEQKAREVCHL-EAELKNIKQCLNQSQNFAEEM---KAK 529
Query: 865 NVPRE------MEKI-QEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD 917
N +E EKI Q+ N +EK K + D L K+ D +D + K+E + L+D
Sbjct: 530 NTSQETMLRDLQEKINQQENSLTLEKLKLAVAD---LEKQRDCSQDLLKKREHHIEQLND 586
Query: 918 NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSEL 977
L + +K+ L L + K+E KE + + + T SE
Sbjct: 587 KL---------SKTEKESKALLSALE-LKKKEYELKEEKTLFSCWKSENEKLLTQMESE- 635
Query: 978 KKSLKGFRNELEKSLSKDIEK--KFREKMYELHVTKA-IDKDIREYAVALDKCLMEFHRE 1034
K++L+ N LE L K ++ E++ L + + + +IR LD +E +
Sbjct: 636 KENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEVETQ 695
Query: 1035 KMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQSK 1084
K+ + + + + +I+ + +KT LT + E ++ +++ ++
Sbjct: 696 KLAYMELQQKAEFSDQKHQKEIENMCLKT-SQLTGQVEDLEHKLQLLSNE 744
Score = 44.0 bits (99), Expect = 0.003
Identities = 59/296 (19%), Positives = 119/296 (40%), Gaps = 26/296 (8%)
Query: 722 LDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
LD A+ + + KI+ L R++ +K++ K Q L + KAK EL+
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELI--------- 330
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
K+++ + C + AL++K++ TE + R A SA
Sbjct: 331 -----EKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ--NAESARC 383
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ + K K E+ + ++ + E IQ +L ++ +Q VL ++D L
Sbjct: 384 SLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQ-MKARLTQELQQAKNMHNVLQAELDKL 442
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
+ E + LC +A+ Q +++EL + + KE K K
Sbjct: 443 TSVKQQLENNLEEFKQKLC--RAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAR 500
Query: 962 KLFQQKAE------CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK 1011
++ +AE C + +K +N ++++ +D+++K ++ L + K
Sbjct: 501 EVCHLEAELKNIKQCLNQSQNFAEEMKA-KNTSQETMLRDLQEKINQQENSLTLEK 555
>BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 61.3 bits (142), Expect = 2e-08
Identities = 125/632 (19%), Positives = 262/632 (41%), Gaps = 54/632 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+ + + +I ++E VE+++++ +L ++ +LQ KE M E + K +++ ++
Sbjct: 560 VGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQ------KELSMCEMEREKKGRKVTEME 613
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
+ K +L ++P + F + EV + + ++ + E
Sbjct: 614 GQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKREL-E 672
Query: 513 SLNERRSELTKAED-KIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQ 571
++ + ++ K E+ + K+ Q K T K Q Q ++ +++ NK +
Sbjct: 673 NVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE-KVYLDNKLLKE 731
Query: 572 LKDNSCCPLCNRGFE-NESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDE-ILSM 629
N + N SE +N KL VT+ + ++ +L
Sbjct: 732 QAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLN--RKLLDVTQKYTEKKLEMEKLLLEN 789
Query: 630 KSLNEKITTLKDTEIP--QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM--TTAKQI 685
SL++ ++ L+ +P + EK I+ + + I L + + E+ E ++K+ T++
Sbjct: 790 DSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENT 849
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ M ++Y+ K E VK D TL + +D K+K +
Sbjct: 850 NLKKMMSNQYVP-----VKTHEEVKMTLND-----TLAKTNRELLDVKKKFEDINQEFVK 899
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+ K + L+ + + K E ++ + + +L +S +++Q
Sbjct: 900 IKDKNEILKRNLE---NTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKG 956
Query: 806 XXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI-----QQ 860
I V L +I+A+ + + ++ I+ A I E K K+ + E+ +Q
Sbjct: 957 QEEI----VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQ 1012
Query: 861 HKKKNV-PREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL 919
+K +V E++K ++ NDKL +K+I T ++ L K ++ + R D+
Sbjct: 1013 TQKYSVSEEEVKKNKQENDKL---KKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDE-- 1067
Query: 920 CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKK 979
L K D++ + + EKL EE ++ S I+ L Q++ + LKK
Sbjct: 1068 -LNKQLKDLSQKYTEVKNVKEKL----VEENAKQTSEILAVQNLLQKQHVPLEQVEALKK 1122
Query: 980 SLKGFRNELE---KSLSKDIEKKFREKMYELH 1008
SL G L+ KS+ + EK+ ++ + +LH
Sbjct: 1123 SLNGTIENLKEELKSMQRCYEKE-QQTVTKLH 1153
Score = 56.4 bits (130), Expect = 6e-07
Identities = 122/689 (17%), Positives = 284/689 (41%), Gaps = 52/689 (7%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+NE K + + E+E ++ +I +L+++ +K K + +++K +E + + K+
Sbjct: 642 EVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAK--LAQHVKPEEHEQV------KSR 693
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L + G + +K +T+ + E +E + ++ ++E
Sbjct: 694 LEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSE-- 751
Query: 519 SELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCC 578
++ K+ D I + DVT KYT +KL+ E+ +L++ ++K +L+
Sbjct: 752 -DMKKSHDAIIDDLNRKLLDVT-QKYTE--KKLEMEKLLLENDS--LSKDVSRLETVFVP 805
Query: 579 PLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSL--NEKI 636
P ++E E + +K ED ++ A E ++K + N+ +
Sbjct: 806 P-----EKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYV 860
Query: 637 TTLKDTEIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ-IHGDMPMLDR 694
E+ L + + ++ + + E+I ++ + K K+ + +
Sbjct: 861 PVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKA 920
Query: 695 YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+ K ++ + V +A ++ +++I TL +K +K+L+
Sbjct: 921 EYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRK--GQEEIVTLHAEIKAQKKELDTIQ 978
Query: 755 KKLQTLYEKKTKAKE---ELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
+ ++ Y +E + T+K+++D ++ E+++K S+ +
Sbjct: 979 ECIKVKYAPIVSFEECERKFKATEKELKDQLS-EQTQKYSVSE--EEVKKNKQENDKLKK 1035
Query: 812 LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREME 871
L++ + KT ++ ++ ++ A S ++ + E++ K+K V +
Sbjct: 1036 EIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK 1095
Query: 872 KIQE--ANDKLMEKQ----KQIMTDRQVLTKKIDTLKDEI-AKQEVYKRDLDDNLCLRKA 924
+ E A L++KQ +Q+ ++ L I+ LK+E+ + Q Y++ + + K
Sbjct: 1096 QTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEK---EQQTVTKL 1152
Query: 925 QTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
+ N + L E L +E EKE IIK L +++ E + E+ K
Sbjct: 1153 HQLLENQKNSSVPLAEHL---QIKEAFEKEVGIIK-ASLREKEEESQNKMEEVSKLQSEV 1208
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIR 1044
+N K K +E + ++ +L KA D+ +L++ L +R+ E ++
Sbjct: 1209 QN--TKQALKKLETR---EVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLH 1263
Query: 1045 ELWRKIYRGNDIDYIEIKTEGNLTVESER 1073
++I ++ + + E + + ER
Sbjct: 1264 AKKKEISAKDEKELLHFSIEQEIKDQKER 1292
Score = 46.8 bits (106), Expect = 5e-04
Identities = 110/591 (18%), Positives = 227/591 (38%), Gaps = 48/591 (8%)
Query: 195 KKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFI 254
K+I K Y N KLL+ A + + K K + K + I ++ + ++ +
Sbjct: 717 KEIEKVYLDN-KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKY 775
Query: 255 LLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQK 314
+ EK+ N+ + + ++ +E + E+ E + + LK K
Sbjct: 776 TEKKLEMEKLLLENDSL--SKDVSRLETV--FVPPEKHEKEIIALKSNIVELKKQLSELK 831
Query: 315 SQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXX 374
+ E+++K E + + + N+
Sbjct: 832 KKCGEDQEKIHALTSE-NTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKF 890
Query: 375 XXXXXXXXXHKQAENEL---NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL 431
K +NE+ N+E Q +I + ++ ++E +M LSQ + K+Q A+
Sbjct: 891 EDINQEFVKIKD-KNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAE- 948
Query: 432 KEKEMIEENLKTKEKQLIVLKNKHKTALMEL--LGNVPEKDFAVTINKFECEVRNEVXXX 489
I N + +++++ L + K EL + + +A ++ ECE + +
Sbjct: 949 -----ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEK 1003
Query: 490 XXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTV 548
E +K+ S++E + K E DK+ K T D L T +
Sbjct: 1004 ELKDQLS-------EQTQKY---SVSEEEVKKNKQENDKLKKEIFTLQKD--LRDKTVLI 1051
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
EK + + L +NK QLKD S + + + V
Sbjct: 1052 EKSHEMERALSRKTDELNK---QLKDLS--QKYTEVKNVKEKLVEENAKQTSEILAVQNL 1106
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
L+K L++ A K KSLN I LK+ E+ +++ + L++ +E
Sbjct: 1107 LQKQHVPLEQVEALK------KSLNGTIENLKE-ELKSMQRCYEKEQQTVTKLHQLLENQ 1159
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDV-DSEMTLDVAT 726
S + + + + ++ ++ ++E + ++ K E V + +V +++ L
Sbjct: 1160 KNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLE 1219
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
++V K ++ ++T ++++ N+KL L K + EE+L+ +KK
Sbjct: 1220 TREVVDLSKYKATKSDLET---QISSLNEKLANLNRKYEEVCEEVLHAKKK 1267
Score = 40.3 bits (90), Expect = 0.041
Identities = 79/417 (18%), Positives = 180/417 (43%), Gaps = 42/417 (10%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIEENLKTKEKQLI 449
++ EEC+++ EK + + ++ E +QK + +++ K K E + +++ + T +K L
Sbjct: 989 VSFEECERKFKATEK---ELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDL- 1044
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+ KT L+E + +++ E+ ++ + K
Sbjct: 1045 ----RDKTVLIE-----KSHEMERALSRKTDELNKQLKDLSQKYTEVK------NVKEKL 1089
Query: 510 IRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDE----QNVLQSSMFI 564
+ E+ + SE+ ++ + K + + T+E L++E Q +
Sbjct: 1090 VEENAKQT-SEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQT 1148
Query: 565 INKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
+ K L++ NS PL E+ ++ K E+ ++ S
Sbjct: 1149 VTKLHQLLENQKNSSVPLA----EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKL 1204
Query: 623 KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTA 682
+ E+ + K +K+ T + ++ + + D++TQI +LNE + + E +++ A
Sbjct: 1205 QSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHA 1264
Query: 683 KQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCG---DVDSEMTLDV-ATAKQVDFK-QKIS 737
K+ ++ D ++ ++ + KE+C +E+ + +AKQ++ K KI+
Sbjct: 1265 KK--KEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKIT 1322
Query: 738 TLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT-QKKVQDI-VNLEESKKQLQ 792
L N V+ ++ LN ++ T TK + +L++T Q +V+ + L ++ +Q Q
Sbjct: 1323 ELLNDVERLKQALNGLSQLTYT-SGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQ 1378
Score = 35.1 bits (77), Expect = 1.5
Identities = 49/269 (18%), Positives = 126/269 (46%), Gaps = 25/269 (9%)
Query: 72 VNRSTEVLGQVKLKIVNAKD---KQLEVTRSM---KVTALAKKKTKFQTLDSFLSTVDES 125
V + E + Q +KI + + + LE T++ + +LA+ + K +L + V +S
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 126 GKTKDVSSRCADLDIL-MHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERF------ 178
+ R +I+ +H E+ K L+++ C + + P+ ++ + +F
Sbjct: 946 NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA-PIVSFEECERKFKATEKE 1004
Query: 179 --DEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKE 235
D++ + KYS + +KK +++ + K + ++ K +E S++ + +++
Sbjct: 1005 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 1064
Query: 236 EEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQ--TNEEAE 293
+++ + +Y + +EK+ + N + +T++I ++N+ + Q E+ E
Sbjct: 1065 TDELNKQLKDLSQKYTEV----KNVKEKLVEENAK--QTSEILAVQNLLQKQHVPLEQVE 1118
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEK 322
K++ +E+LK + K + ++E++
Sbjct: 1119 ALKKSLNGTIENLKEELKSMQRCYEKEQQ 1147
Score = 34.7 bits (76), Expect = 2.0
Identities = 27/152 (17%), Positives = 72/152 (47%), Gaps = 18/152 (11%)
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
+ ++ H++++ + ++ ++ N+ L E+ ++I ++++L K++ L+ ++ ++ + D
Sbjct: 283 EVNVKSHQREH--QNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADD 340
Query: 915 LDDNLCLRKAQTDITNWQKQDDE-------LNEKLNGINKEEL-------NEKESLIIKQ 960
L+ K ++ + +KQ +E L + + L N KE +++KQ
Sbjct: 341 LESER--EKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQ 398
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
+++ ++CT + LE SL
Sbjct: 399 GQMYMADSQCTSPGIPAHMQSRSMLRPLELSL 430
>BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 61.3 bits (142), Expect = 2e-08
Identities = 125/632 (19%), Positives = 262/632 (41%), Gaps = 54/632 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+ + + +I ++E VE+++++ +L ++ +LQ KE M E + K +++ ++
Sbjct: 560 VGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQ------KELSMCEMEREKKGRKVTEME 613
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
+ K +L ++P + F + EV + + ++ + E
Sbjct: 614 GQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKREL-E 672
Query: 513 SLNERRSELTKAED-KIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQ 571
++ + ++ K E+ + K+ Q K T K Q Q ++ +++ NK +
Sbjct: 673 NVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE-KVYLDNKLLKE 731
Query: 572 LKDNSCCPLCNRGFE-NESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDE-ILSM 629
N + N SE +N KL VT+ + ++ +L
Sbjct: 732 QAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLN--RKLLDVTQKYTEKKLEMEKLLLEN 789
Query: 630 KSLNEKITTLKDTEIP--QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM--TTAKQI 685
SL++ ++ L+ +P + EK I+ + + I L + + E+ E ++K+ T++
Sbjct: 790 DSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENT 849
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ M ++Y+ K E VK D TL + +D K+K +
Sbjct: 850 NLKKMMSNQYVP-----VKTHEEVKMTLND-----TLAKTNRELLDVKKKFEDINQEFVK 899
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+ K + L+ + + K E ++ + + +L +S +++Q
Sbjct: 900 IKDKNEILKRNLE---NTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKG 956
Query: 806 XXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI-----QQ 860
I V L +I+A+ + + ++ I+ A I E K K+ + E+ +Q
Sbjct: 957 QEEI----VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQ 1012
Query: 861 HKKKNV-PREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL 919
+K +V E++K ++ NDKL +K+I T ++ L K ++ + R D+
Sbjct: 1013 TQKYSVSEEEVKKNKQENDKL---KKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDE-- 1067
Query: 920 CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKK 979
L K D++ + + EKL EE ++ S I+ L Q++ + LKK
Sbjct: 1068 -LNKQLKDLSQKYTEVKNVKEKL----VEENAKQTSEILAVQNLLQKQHVPLEQVEALKK 1122
Query: 980 SLKGFRNELE---KSLSKDIEKKFREKMYELH 1008
SL G L+ KS+ + EK+ ++ + +LH
Sbjct: 1123 SLNGTIENLKEELKSMQRCYEKE-QQTVTKLH 1153
Score = 56.4 bits (130), Expect = 6e-07
Identities = 122/689 (17%), Positives = 284/689 (41%), Gaps = 52/689 (7%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+NE K + + E+E ++ +I +L+++ +K K + +++K +E + + K+
Sbjct: 642 EVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAK--LAQHVKPEEHEQV------KSR 693
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L + G + +K +T+ + E +E + ++ ++E
Sbjct: 694 LEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSE-- 751
Query: 519 SELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCC 578
++ K+ D I + DVT KYT +KL+ E+ +L++ ++K +L+
Sbjct: 752 -DMKKSHDAIIDDLNRKLLDVT-QKYTE--KKLEMEKLLLENDS--LSKDVSRLETVFVP 805
Query: 579 PLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSL--NEKI 636
P ++E E + +K ED ++ A E ++K + N+ +
Sbjct: 806 P-----EKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYV 860
Query: 637 TTLKDTEIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ-IHGDMPMLDR 694
E+ L + + ++ + + E+I ++ + K K+ + +
Sbjct: 861 PVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKA 920
Query: 695 YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+ K ++ + V +A ++ +++I TL +K +K+L+
Sbjct: 921 EYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRK--GQEEIVTLHAEIKAQKKELDTIQ 978
Query: 755 KKLQTLYEKKTKAKE---ELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
+ ++ Y +E + T+K+++D ++ E+++K S+ +
Sbjct: 979 ECIKVKYAPIVSFEECERKFKATEKELKDQLS-EQTQKYSVSE--EEVKKNKQENDKLKK 1035
Query: 812 LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREME 871
L++ + KT ++ ++ ++ A S ++ + E++ K+K V +
Sbjct: 1036 EIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK 1095
Query: 872 KIQE--ANDKLMEKQ----KQIMTDRQVLTKKIDTLKDEI-AKQEVYKRDLDDNLCLRKA 924
+ E A L++KQ +Q+ ++ L I+ LK+E+ + Q Y++ + + K
Sbjct: 1096 QTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEK---EQQTVTKL 1152
Query: 925 QTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
+ N + L E L +E EKE IIK L +++ E + E+ K
Sbjct: 1153 HQLLENQKNSSVPLAEHL---QIKEAFEKEVGIIK-ASLREKEEESQNKMEEVSKLQSEV 1208
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIR 1044
+N K K +E + ++ +L KA D+ +L++ L +R+ E ++
Sbjct: 1209 QN--TKQALKKLETR---EVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLH 1263
Query: 1045 ELWRKIYRGNDIDYIEIKTEGNLTVESER 1073
++I ++ + + E + + ER
Sbjct: 1264 AKKKEISAKDEKELLHFSIEQEIKDQKER 1292
Score = 46.8 bits (106), Expect = 5e-04
Identities = 110/591 (18%), Positives = 227/591 (38%), Gaps = 48/591 (8%)
Query: 195 KKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFI 254
K+I K Y N KLL+ A + + K K + K + I ++ + ++ +
Sbjct: 717 KEIEKVYLDN-KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKY 775
Query: 255 LLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQK 314
+ EK+ N+ + + ++ +E + E+ E + + LK K
Sbjct: 776 TEKKLEMEKLLLENDSL--SKDVSRLETV--FVPPEKHEKEIIALKSNIVELKKQLSELK 831
Query: 315 SQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXX 374
+ E+++K E + + + N+
Sbjct: 832 KKCGEDQEKIHALTSE-NTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKF 890
Query: 375 XXXXXXXXXHKQAENEL---NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL 431
K +NE+ N+E Q +I + ++ ++E +M LSQ + K+Q A+
Sbjct: 891 EDINQEFVKIKD-KNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAE- 948
Query: 432 KEKEMIEENLKTKEKQLIVLKNKHKTALMEL--LGNVPEKDFAVTINKFECEVRNEVXXX 489
I N + +++++ L + K EL + + +A ++ ECE + +
Sbjct: 949 -----ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEK 1003
Query: 490 XXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTV 548
E +K+ S++E + K E DK+ K T D L T +
Sbjct: 1004 ELKDQLS-------EQTQKY---SVSEEEVKKNKQENDKLKKEIFTLQKD--LRDKTVLI 1051
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
EK + + L +NK QLKD S + + + V
Sbjct: 1052 EKSHEMERALSRKTDELNK---QLKDLS--QKYTEVKNVKEKLVEENAKQTSEILAVQNL 1106
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
L+K L++ A K KSLN I LK+ E+ +++ + L++ +E
Sbjct: 1107 LQKQHVPLEQVEALK------KSLNGTIENLKE-ELKSMQRCYEKEQQTVTKLHQLLENQ 1159
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDV-DSEMTLDVAT 726
S + + + + ++ ++ ++E + ++ K E V + +V +++ L
Sbjct: 1160 KNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLE 1219
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
++V K ++ ++T ++++ N+KL L K + EE+L+ +KK
Sbjct: 1220 TREVVDLSKYKATKSDLET---QISSLNEKLANLNRKYEEVCEEVLHAKKK 1267
Score = 40.3 bits (90), Expect = 0.041
Identities = 79/417 (18%), Positives = 180/417 (43%), Gaps = 42/417 (10%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIEENLKTKEKQLI 449
++ EEC+++ EK + + ++ E +QK + +++ K K E + +++ + T +K L
Sbjct: 989 VSFEECERKFKATEK---ELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDL- 1044
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+ KT L+E + +++ E+ ++ + K
Sbjct: 1045 ----RDKTVLIE-----KSHEMERALSRKTDELNKQLKDLSQKYTEVK------NVKEKL 1089
Query: 510 IRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDE----QNVLQSSMFI 564
+ E+ + SE+ ++ + K + + T+E L++E Q +
Sbjct: 1090 VEENAKQT-SEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQT 1148
Query: 565 INKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
+ K L++ NS PL E+ ++ K E+ ++ S
Sbjct: 1149 VTKLHQLLENQKNSSVPLA----EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKL 1204
Query: 623 KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTA 682
+ E+ + K +K+ T + ++ + + D++TQI +LNE + + E +++ A
Sbjct: 1205 QSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHA 1264
Query: 683 KQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCG---DVDSEMTLDV-ATAKQVDFK-QKIS 737
K+ ++ D ++ ++ + KE+C +E+ + +AKQ++ K KI+
Sbjct: 1265 KK--KEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKIT 1322
Query: 738 TLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT-QKKVQDI-VNLEESKKQLQ 792
L N V+ ++ LN ++ T TK + +L++T Q +V+ + L ++ +Q Q
Sbjct: 1323 ELLNDVERLKQALNGLSQLTYT-SGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQ 1378
Score = 35.1 bits (77), Expect = 1.5
Identities = 49/269 (18%), Positives = 126/269 (46%), Gaps = 25/269 (9%)
Query: 72 VNRSTEVLGQVKLKIVNAKD---KQLEVTRSM---KVTALAKKKTKFQTLDSFLSTVDES 125
V + E + Q +KI + + + LE T++ + +LA+ + K +L + V +S
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 126 GKTKDVSSRCADLDIL-MHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERF------ 178
+ R +I+ +H E+ K L+++ C + + P+ ++ + +F
Sbjct: 946 NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA-PIVSFEECERKFKATEKE 1004
Query: 179 --DEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKE 235
D++ + KYS + +KK +++ + K + ++ K +E S++ + +++
Sbjct: 1005 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 1064
Query: 236 EEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQ--TNEEAE 293
+++ + +Y + +EK+ + N + +T++I ++N+ + Q E+ E
Sbjct: 1065 TDELNKQLKDLSQKYTEV----KNVKEKLVEENAK--QTSEILAVQNLLQKQHVPLEQVE 1118
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEK 322
K++ +E+LK + K + ++E++
Sbjct: 1119 ALKKSLNGTIENLKEELKSMQRCYEKEQQ 1147
Score = 34.7 bits (76), Expect = 2.0
Identities = 27/152 (17%), Positives = 72/152 (47%), Gaps = 18/152 (11%)
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
+ ++ H++++ + ++ ++ N+ L E+ ++I ++++L K++ L+ ++ ++ + D
Sbjct: 283 EVNVKSHQREH--QNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADD 340
Query: 915 LDDNLCLRKAQTDITNWQKQDDE-------LNEKLNGINKEEL-------NEKESLIIKQ 960
L+ K ++ + +KQ +E L + + L N KE +++KQ
Sbjct: 341 LESER--EKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQ 398
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
+++ ++CT + LE SL
Sbjct: 399 GQMYMADSQCTSPGIPAHMQSRSMLRPLELSL 430
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 61.3 bits (142), Expect = 2e-08
Identities = 125/639 (19%), Positives = 262/639 (41%), Gaps = 50/639 (7%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEM-IEENLKTKEKQLIVL 451
+E E E + ++E+ +L + I KL+ + ++K++ I E LK +E++ L
Sbjct: 2093 LEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSL 2152
Query: 452 KNKHKTALMELLGNVPEKDFAVTI---NKFECE-VRNEVXXXXXXXXXXXXXXXXLEAER 507
K+K + EL + ++ + +K E E ++ ++ L +E+
Sbjct: 2153 KDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK 2212
Query: 508 KHIRESLNERRSELTKAEDKI--YKACGTQPYDVTLS---KYTTTVEKLQDEQNVLQSSM 562
+++ + + E++ +L++ + + +K+ + + + T VE LQ++ L ++
Sbjct: 2213 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2272
Query: 563 FIINKYKGQLK--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS 620
+ + +K + S P + + L+++ E A
Sbjct: 2273 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD 2332
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMT 680
K + +++ E T ++ + E +++TL +E +T SL E +
Sbjct: 2333 LLKGRVENLERELEIARTNQEHAALEAENS----KGEVETLKAKIEGMTQSLRGLELDVV 2388
Query: 681 TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLR 740
T I + L +Q+ + + E + ++ L ++V K+K ST
Sbjct: 2389 T---IRSEKENLTNELQKEQERISELEIINSSFENI-----LQEKEQEKVQMKEKSSTAM 2440
Query: 741 NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXX 800
++T K+LN L E KAKE+ L++Q + LE K QL
Sbjct: 2441 EMLQTQLKELNERVAALHNDQEA-CKAKEQNLSSQVEC-----LELEKAQLLQGLDEAKN 2494
Query: 801 XXXXXXXAITPLEVAL---KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
++ L + K+K+E K E + R ++ I+ E +K+ ++ E
Sbjct: 2495 NYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQ-------DQEQLVSKLSQVEGE 2547
Query: 858 IQQHKKKNVP-REME-KIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
Q K++N+ R + ++++ L K + +VL L++E+ ++ K
Sbjct: 2548 HQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSF 2607
Query: 916 DDNLCLRKA-----QTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ-QKAE 969
+ + A Q ++ ++ EL E+L+G K L + L++++ K + Q E
Sbjct: 2608 VEKVNKMTAKETELQREMHEMAQKTAELQEELSG-EKNRLAGELQLLLEEIKSSKDQLKE 2666
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
T SELKKSL + + K + ++ E LH
Sbjct: 2667 LTLENSELKKSLDCMHKDQVEKEGK-VREEIAEYQLRLH 2704
Score = 56.4 bits (130), Expect = 6e-07
Identities = 116/632 (18%), Positives = 263/632 (41%), Gaps = 46/632 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK--QTAKLKEKEMIEENLK 442
+QA+N N+ Q E+++ +Q E ++E QK+ + ++ Q +++KE E+ +++
Sbjct: 426 QQAKNMHNV--LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL-RRSME 482
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
+K+ +LK+ + E+ E K+ +N+ + N
Sbjct: 483 EMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ----NFAEEMKAKNTSQETMLR 538
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGT---QPYDVTLSKYTTTVEKLQDEQNVL 558
L+ + SL + +L A+ + + C + + + + + K + E L
Sbjct: 539 DLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Query: 559 QSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
S++ + K +LK+ C + ENE N+ K+ + L+
Sbjct: 599 LSALELKKKEYEELKEEKTLFSCWKS-ENEK----LLTQMESEKENLQSKINHLETCLKT 653
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
K E NE++ TL + + L I ++ + + + VE ++ +E +QK
Sbjct: 654 QQIKSHEY------NERVRTL-EMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQK 706
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q H ++ + +T + E ++ + + +E+ +D Q D + +
Sbjct: 707 AEFSDQKH--QKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI-MDKDRCYQ-DLHAEYES 762
Query: 739 LRNRVKTTQKKL--NAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCX 796
LR+ +K+ L N +++ ++++ N + Q + E S+ +L++D
Sbjct: 763 LRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGE-QGSMPSERSECRLEAD-- 819
Query: 797 XXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDA 856
+ LE +L+ + + +++ ++ +L++ + A +S A
Sbjct: 820 QSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVA 879
Query: 857 EIQQHKKK---NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
E Q K + + E L K+K++ Q+L K++T + EI + +
Sbjct: 880 ETSQRISKLQEDTSAHQNVVAETLSALENKEKEL----QLLNDKVETEQAEIQELKKSNH 935
Query: 914 DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAECTG 972
L+D+L + ++ + +K++ LN EEL ++ + + L Q+K
Sbjct: 936 LLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN--- 992
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
L + +S + +E EKS+S+ ++ +EK+
Sbjct: 993 -LIQKSESFANYIDEREKSISELSDQYKQEKL 1023
Score = 55.6 bits (128), Expect = 1e-06
Identities = 140/764 (18%), Positives = 312/764 (40%), Gaps = 89/764 (11%)
Query: 181 IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIA 240
I DA+ ++ LK ++ A++LK+ E T++++++ L ++ E +K+
Sbjct: 2174 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLL 2233
Query: 241 NE-KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK-IAEIENITEVQTNEEAENATKT 298
+ KS E + I ++ +++ ++ Q+ E + +A + E+ + E +
Sbjct: 2234 SSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIM--KATEQSLDP 2291
Query: 299 ILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXX 358
+E+ L++ + +++ + +EKK + + +
Sbjct: 2292 PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL------ 2345
Query: 359 DITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELS 418
+I NQ K IE Q + E V E + L+
Sbjct: 2346 EIARTNQEHAALEAENSKGEVETLKAK-------IEGMTQSLRGLELDVVTIRSEKENLT 2398
Query: 419 QKITKLQKQTAKLKEKEMIEEN-LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINK 477
++ K Q++ ++L+ EN L+ KE++ + +K K TA+ L + E +N+
Sbjct: 2399 NELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKE------LNE 2452
Query: 478 FECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPY 537
+ N+ LE E+ + + L+E ++ Y
Sbjct: 2453 RVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNN----------------Y 2496
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
V S +++++D + L+ I++ K Q++D L ++ + E E
Sbjct: 2497 IVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQE--QLVSKLSQVEGEHQLWKEQ 2554
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEIL-----SMKSLNEKITTLKDTEIPQLEKRIV 652
N+ +LE+ + LQ +A + L S K+L ++ K ++ +EK +
Sbjct: 2555 NLELR-NLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VN 2612
Query: 653 DVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
+ + L + E+ E +++++ K ++ G++ +L ++EIK+ + + +
Sbjct: 2613 KMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLL---LEEIKSSKDQLKELTL 2669
Query: 712 QCGDVDSEMTLDVATAKQVD----FKQKISTLRNRVKTTQKKLNA----HNKKLQT---L 760
+ ++ + +LD QV+ +++I+ + R+ +KK A NK+ +
Sbjct: 2670 ENSEL--KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQT 2727
Query: 761 YEKKTKAKEELLNTQKKVQDIVN----------------LEESKKQLQSDCXXXXXXXXX 804
Y +K +KEE L++QK D++ LEE KK +
Sbjct: 2728 YREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKE 2787
Query: 805 XXXAITPLEVALK--EKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK 862
A +++ +K +++E + E++++ ++A V KV L EI++ K
Sbjct: 2788 NERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELK 2847
Query: 863 KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
+ EK +EA D+ ++K ++ + L K + L+ ++A
Sbjct: 2848 E----TLEEKTKEA-DEYLDKYCSLLISHEKLEKAKEMLETQVA 2886
Score = 49.6 bits (113), Expect = 7e-05
Identities = 92/463 (19%), Positives = 215/463 (46%), Gaps = 59/463 (12%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTL-KDTEIP-----QLEKRIVDVDTQIKT 660
++++ TE LQ S+ E+L K+ L EK+ +L KD++ +LE +I ++ + +
Sbjct: 2008 EVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKEL 2067
Query: 661 LNETVEEITMSLIEPE-QKMTTAKQIH------GDMPM-LDRYIQEIKTVTKKFEAVKEQ 712
L + E + L E + +K+ +K + G+ + L +E+ + + E ++ +
Sbjct: 2068 LVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVR 2127
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL--NAHNKKLQTLYEKKTKAKEE 770
+ D + L +A K + +++ +L+++V+ +++L + N++L L + +KA+ E
Sbjct: 2128 I-EADEKKQLHIAE-KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVE 2185
Query: 771 LLNTQKKVQ---------DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE 821
L TQ + D+V L K+ L ++ + L+EK +
Sbjct: 2186 TLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQ 2245
Query: 822 AKTEVVRRN-----------RDLIEAGSAYIAKVEVAFNKVKSLDAEI-QQHKKKNVPRE 869
A+ ++ + ++L EA +A E+ +SLD I ++H+ +N +
Sbjct: 2246 AEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2305
Query: 870 MEKIQEANDK----LMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD-NLCLRKA 924
+ EA++K ++++ K+ +L +++ L+ E+ E+ + + + L +
Sbjct: 2306 LRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL---EIARTNQEHAALEAENS 2362
Query: 925 QTDITNWQKQDDELNEKLNGINKEEL---NEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ ++ + + + + + L G+ + + +EKE+L T Q++ E +SEL+
Sbjct: 2363 KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENL----TNELQKEQE---RISELEIIN 2415
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVAL 1024
F N L++ + ++ K + + + + K++ E AL
Sbjct: 2416 SSFENILQEKEQEKVQMK-EKSSTAMEMLQTQLKELNERVAAL 2457
Score = 46.0 bits (104), Expect = 8e-04
Identities = 102/475 (21%), Positives = 203/475 (42%), Gaps = 55/475 (11%)
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K + ++ ++ ++ QLEK V++ + K LN+ +E+ + + +Q T + +
Sbjct: 306 KEMKGQVNKFQELQL-QLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKL 364
Query: 690 PMLDRYI----QEIKTVTKKFE-AVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK 744
L + Q ++ E +KE+ + E++ + + +D ++ I +
Sbjct: 365 KKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLD-QECIQMKARLTQ 423
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q+ N HN LQ +K T K++L N NLEE K++L
Sbjct: 424 ELQQAKNMHN-VLQAELDKLTSVKQQLEN---------NLEEFKQKLCRAEQAFQASQIK 473
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
+E KE K+ ++ R++ A + ++ N+ ++ E+ K K
Sbjct: 474 ENELRRSMEEMKKENNLLKSHSEQKAREVCHL-EAELKNIKQCLNQSQNFAEEM---KAK 529
Query: 865 NVPRE------MEKI-QEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD 917
N +E EKI Q+ N +EK K + D L K+ D +D + K+E + L+D
Sbjct: 530 NTSQETMLRDLQEKINQQENSLTLEKLKLAVAD---LEKQRDCSQDLLKKREHHIEQLND 586
Query: 918 NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK-LFQ-QKAECTGALS 975
L K + E L+ + EL +KE +K+ K LF K+E L+
Sbjct: 587 KL------------SKTEKESKALLSAL---ELKKKEYEELKEEKTLFSCWKSENEKLLT 631
Query: 976 EL---KKSLKGFRNELEKSLSKDIEK--KFREKMYELHVTKA-IDKDIREYAVALDKCLM 1029
++ K++L+ N LE L K ++ E++ L + + + +IR LD +
Sbjct: 632 QMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSV 691
Query: 1030 EFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQSK 1084
E +K+ + + + + +I+ + +KT LT + E ++ +++ ++
Sbjct: 692 EVETQKLAYMELQQKAEFSDQKHQKEIENMCLKT-SQLTGQVEDLEHKLQLLSNE 745
Score = 44.8 bits (101), Expect = 0.002
Identities = 76/428 (17%), Positives = 171/428 (39%), Gaps = 32/428 (7%)
Query: 722 LDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
LD A+ + + KI+ L R++ +K++ K Q L + KAK EL+
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELI--------- 330
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
K+++ + C + AL++K++ TE + R A SA
Sbjct: 331 -----EKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ--NAESARC 383
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ + K K E+ + ++ + E IQ +L ++ +Q VL ++D L
Sbjct: 384 SLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQ-MKARLTQELQQAKNMHNVLQAELDKL 442
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
+ E + LC +A+ Q +++EL + + KE K K
Sbjct: 443 TSVKQQLENNLEEFKQKLC--RAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAR 500
Query: 962 KLFQQKAE------CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
++ +AE C + +K +N ++++ +D+++K ++ L + K +
Sbjct: 501 EVCHLEAELKNIKQCLNQSQNFAEEMKA-KNTSQETMLRDLQEKINQQENSLTLEK-LKL 558
Query: 1016 DIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGND-IDYIEIKTEGNLTVESERR 1074
+ + D C + +++ +I + +L + + +E+K + ++ E+
Sbjct: 559 AVADLEKQRD-CSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKT 617
Query: 1075 KYD-YRVVQSK--NGVEIDMRGRCSAGQKVLACLIIRLALAETFSSRFGILALDEPTTNL 1131
+ ++ K +E + S + CL + + ++ R L +D ++
Sbjct: 618 LFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSV 677
Query: 1132 DQENIHSL 1139
+ N+H++
Sbjct: 678 EIRNLHNV 685
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 61.3 bits (142), Expect = 2e-08
Identities = 125/639 (19%), Positives = 262/639 (41%), Gaps = 50/639 (7%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEM-IEENLKTKEKQLIVL 451
+E E E + ++E+ +L + I KL+ + ++K++ I E LK +E++ L
Sbjct: 2093 LEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSL 2152
Query: 452 KNKHKTALMELLGNVPEKDFAVTI---NKFECE-VRNEVXXXXXXXXXXXXXXXXLEAER 507
K+K + EL + ++ + +K E E ++ ++ L +E+
Sbjct: 2153 KDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK 2212
Query: 508 KHIRESLNERRSELTKAEDKI--YKACGTQPYDVTLS---KYTTTVEKLQDEQNVLQSSM 562
+++ + + E++ +L++ + + +K+ + + + T VE LQ++ L ++
Sbjct: 2213 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2272
Query: 563 FIINKYKGQLK--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS 620
+ + +K + S P + + L+++ E A
Sbjct: 2273 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD 2332
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMT 680
K + +++ E T ++ + E +++TL +E +T SL E +
Sbjct: 2333 LLKGRVENLERELEIARTNQEHAALEAENS----KGEVETLKAKIEGMTQSLRGLELDVV 2388
Query: 681 TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLR 740
T I + L +Q+ + + E + ++ L ++V K+K ST
Sbjct: 2389 T---IRSEKENLTNELQKEQERISELEIINSSFENI-----LQEKEQEKVQMKEKSSTAM 2440
Query: 741 NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXX 800
++T K+LN L E KAKE+ L++Q + LE K QL
Sbjct: 2441 EMLQTQLKELNERVAALHNDQEA-CKAKEQNLSSQVEC-----LELEKAQLLQGLDEAKN 2494
Query: 801 XXXXXXXAITPLEVAL---KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
++ L + K+K+E K E + R ++ I+ E +K+ ++ E
Sbjct: 2495 NYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQ-------DQEQLVSKLSQVEGE 2547
Query: 858 IQQHKKKNVP-REME-KIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
Q K++N+ R + ++++ L K + +VL L++E+ ++ K
Sbjct: 2548 HQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSF 2607
Query: 916 DDNLCLRKA-----QTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ-QKAE 969
+ + A Q ++ ++ EL E+L+G K L + L++++ K + Q E
Sbjct: 2608 VEKVNKMTAKETELQREMHEMAQKTAELQEELSG-EKNRLAGELQLLLEEIKSSKDQLKE 2666
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
T SELKKSL + + K + ++ E LH
Sbjct: 2667 LTLENSELKKSLDCMHKDQVEKEGK-VREEIAEYQLRLH 2704
Score = 56.4 bits (130), Expect = 6e-07
Identities = 116/632 (18%), Positives = 263/632 (41%), Gaps = 46/632 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK--QTAKLKEKEMIEENLK 442
+QA+N N+ Q E+++ +Q E ++E QK+ + ++ Q +++KE E+ +++
Sbjct: 426 QQAKNMHNV--LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL-RRSME 482
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
+K+ +LK+ + E+ E K+ +N+ + N
Sbjct: 483 EMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ----NFAEEMKAKNTSQETMLR 538
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGT---QPYDVTLSKYTTTVEKLQDEQNVL 558
L+ + SL + +L A+ + + C + + + + + K + E L
Sbjct: 539 DLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Query: 559 QSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
S++ + K +LK+ C + ENE N+ K+ + L+
Sbjct: 599 LSALELKKKEYEELKEEKTLFSCWKS-ENEK----LLTQMESEKENLQSKINHLETCLKT 653
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
K E NE++ TL + + L I ++ + + + VE ++ +E +QK
Sbjct: 654 QQIKSHEY------NERVRTL-EMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQK 706
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q H ++ + +T + E ++ + + +E+ +D Q D + +
Sbjct: 707 AEFSDQKH--QKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI-MDKDRCYQ-DLHAEYES 762
Query: 739 LRNRVKTTQKKL--NAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCX 796
LR+ +K+ L N +++ ++++ N + Q + E S+ +L++D
Sbjct: 763 LRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGE-QGSMPSERSECRLEAD-- 819
Query: 797 XXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDA 856
+ LE +L+ + + +++ ++ +L++ + A +S A
Sbjct: 820 QSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVA 879
Query: 857 EIQQHKKK---NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
E Q K + + E L K+K++ Q+L K++T + EI + +
Sbjct: 880 ETSQRISKLQEDTSAHQNVVAETLSALENKEKEL----QLLNDKVETEQAEIQELKKSNH 935
Query: 914 DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAECTG 972
L+D+L + ++ + +K++ LN EEL ++ + + L Q+K
Sbjct: 936 LLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN--- 992
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
L + +S + +E EKS+S+ ++ +EK+
Sbjct: 993 -LIQKSESFANYIDEREKSISELSDQYKQEKL 1023
Score = 55.6 bits (128), Expect = 1e-06
Identities = 140/764 (18%), Positives = 312/764 (40%), Gaps = 89/764 (11%)
Query: 181 IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIA 240
I DA+ ++ LK ++ A++LK+ E T++++++ L ++ E +K+
Sbjct: 2174 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLL 2233
Query: 241 NE-KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK-IAEIENITEVQTNEEAENATKT 298
+ KS E + I ++ +++ ++ Q+ E + +A + E+ + E +
Sbjct: 2234 SSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIM--KATEQSLDP 2291
Query: 299 ILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXX 358
+E+ L++ + +++ + +EKK + + +
Sbjct: 2292 PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL------ 2345
Query: 359 DITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELS 418
+I NQ K IE Q + E V E + L+
Sbjct: 2346 EIARTNQEHAALEAENSKGEVETLKAK-------IEGMTQSLRGLELDVVTIRSEKENLT 2398
Query: 419 QKITKLQKQTAKLKEKEMIEEN-LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINK 477
++ K Q++ ++L+ EN L+ KE++ + +K K TA+ L + E +N+
Sbjct: 2399 NELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKE------LNE 2452
Query: 478 FECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPY 537
+ N+ LE E+ + + L+E ++ Y
Sbjct: 2453 RVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNN----------------Y 2496
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
V S +++++D + L+ I++ K Q++D L ++ + E E
Sbjct: 2497 IVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQE--QLVSKLSQVEGEHQLWKEQ 2554
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEIL-----SMKSLNEKITTLKDTEIPQLEKRIV 652
N+ +LE+ + LQ +A + L S K+L ++ K ++ +EK +
Sbjct: 2555 NLELR-NLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VN 2612
Query: 653 DVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
+ + L + E+ E +++++ K ++ G++ +L ++EIK+ + + +
Sbjct: 2613 KMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLL---LEEIKSSKDQLKELTL 2669
Query: 712 QCGDVDSEMTLDVATAKQVD----FKQKISTLRNRVKTTQKKLNA----HNKKLQT---L 760
+ ++ + +LD QV+ +++I+ + R+ +KK A NK+ +
Sbjct: 2670 ENSEL--KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQT 2727
Query: 761 YEKKTKAKEELLNTQKKVQDIVN----------------LEESKKQLQSDCXXXXXXXXX 804
Y +K +KEE L++QK D++ LEE KK +
Sbjct: 2728 YREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKE 2787
Query: 805 XXXAITPLEVALK--EKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK 862
A +++ +K +++E + E++++ ++A V KV L EI++ K
Sbjct: 2788 NERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELK 2847
Query: 863 KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
+ EK +EA D+ ++K ++ + L K + L+ ++A
Sbjct: 2848 E----TLEEKTKEA-DEYLDKYCSLLISHEKLEKAKEMLETQVA 2886
Score = 49.6 bits (113), Expect = 7e-05
Identities = 92/463 (19%), Positives = 215/463 (46%), Gaps = 59/463 (12%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTL-KDTEIP-----QLEKRIVDVDTQIKT 660
++++ TE LQ S+ E+L K+ L EK+ +L KD++ +LE +I ++ + +
Sbjct: 2008 EVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKEL 2067
Query: 661 LNETVEEITMSLIEPE-QKMTTAKQIH------GDMPM-LDRYIQEIKTVTKKFEAVKEQ 712
L + E + L E + +K+ +K + G+ + L +E+ + + E ++ +
Sbjct: 2068 LVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVR 2127
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL--NAHNKKLQTLYEKKTKAKEE 770
+ D + L +A K + +++ +L+++V+ +++L + N++L L + +KA+ E
Sbjct: 2128 I-EADEKKQLHIAE-KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVE 2185
Query: 771 LLNTQKKVQ---------DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE 821
L TQ + D+V L K+ L ++ + L+EK +
Sbjct: 2186 TLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQ 2245
Query: 822 AKTEVVRRN-----------RDLIEAGSAYIAKVEVAFNKVKSLDAEI-QQHKKKNVPRE 869
A+ ++ + ++L EA +A E+ +SLD I ++H+ +N +
Sbjct: 2246 AEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2305
Query: 870 MEKIQEANDK----LMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD-NLCLRKA 924
+ EA++K ++++ K+ +L +++ L+ E+ E+ + + + L +
Sbjct: 2306 LRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL---EIARTNQEHAALEAENS 2362
Query: 925 QTDITNWQKQDDELNEKLNGINKEEL---NEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ ++ + + + + + L G+ + + +EKE+L T Q++ E +SEL+
Sbjct: 2363 KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENL----TNELQKEQE---RISELEIIN 2415
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVAL 1024
F N L++ + ++ K + + + + K++ E AL
Sbjct: 2416 SSFENILQEKEQEKVQMK-EKSSTAMEMLQTQLKELNERVAAL 2457
Score = 46.0 bits (104), Expect = 8e-04
Identities = 102/475 (21%), Positives = 203/475 (42%), Gaps = 55/475 (11%)
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K + ++ ++ ++ QLEK V++ + K LN+ +E+ + + +Q T + +
Sbjct: 306 KEMKGQVNKFQELQL-QLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKL 364
Query: 690 PMLDRYI----QEIKTVTKKFE-AVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK 744
L + Q ++ E +KE+ + E++ + + +D ++ I +
Sbjct: 365 KKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLD-QECIQMKARLTQ 423
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q+ N HN LQ +K T K++L N NLEE K++L
Sbjct: 424 ELQQAKNMHN-VLQAELDKLTSVKQQLEN---------NLEEFKQKLCRAEQAFQASQIK 473
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
+E KE K+ ++ R++ A + ++ N+ ++ E+ K K
Sbjct: 474 ENELRRSMEEMKKENNLLKSHSEQKAREVCHL-EAELKNIKQCLNQSQNFAEEM---KAK 529
Query: 865 NVPRE------MEKI-QEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD 917
N +E EKI Q+ N +EK K + D L K+ D +D + K+E + L+D
Sbjct: 530 NTSQETMLRDLQEKINQQENSLTLEKLKLAVAD---LEKQRDCSQDLLKKREHHIEQLND 586
Query: 918 NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK-LFQ-QKAECTGALS 975
L K + E L+ + EL +KE +K+ K LF K+E L+
Sbjct: 587 KL------------SKTEKESKALLSAL---ELKKKEYEELKEEKTLFSCWKSENEKLLT 631
Query: 976 EL---KKSLKGFRNELEKSLSKDIEK--KFREKMYELHVTKA-IDKDIREYAVALDKCLM 1029
++ K++L+ N LE L K ++ E++ L + + + +IR LD +
Sbjct: 632 QMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSV 691
Query: 1030 EFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQSK 1084
E +K+ + + + + +I+ + +KT LT + E ++ +++ ++
Sbjct: 692 EVETQKLAYMELQQKAEFSDQKHQKEIENMCLKT-SQLTGQVEDLEHKLQLLSNE 745
Score = 44.8 bits (101), Expect = 0.002
Identities = 76/428 (17%), Positives = 171/428 (39%), Gaps = 32/428 (7%)
Query: 722 LDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI 781
LD A+ + + KI+ L R++ +K++ K Q L + KAK EL+
Sbjct: 280 LDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELI--------- 330
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
K+++ + C + AL++K++ TE + R A SA
Sbjct: 331 -----EKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ--NAESARC 383
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ + K K E+ + ++ + E IQ +L ++ +Q VL ++D L
Sbjct: 384 SLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQ-MKARLTQELQQAKNMHNVLQAELDKL 442
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
+ E + LC +A+ Q +++EL + + KE K K
Sbjct: 443 TSVKQQLENNLEEFKQKLC--RAEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAR 500
Query: 962 KLFQQKAE------CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
++ +AE C + +K +N ++++ +D+++K ++ L + K +
Sbjct: 501 EVCHLEAELKNIKQCLNQSQNFAEEMKA-KNTSQETMLRDLQEKINQQENSLTLEK-LKL 558
Query: 1016 DIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGND-IDYIEIKTEGNLTVESERR 1074
+ + D C + +++ +I + +L + + +E+K + ++ E+
Sbjct: 559 AVADLEKQRD-CSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKT 617
Query: 1075 KYD-YRVVQSK--NGVEIDMRGRCSAGQKVLACLIIRLALAETFSSRFGILALDEPTTNL 1131
+ ++ K +E + S + CL + + ++ R L +D ++
Sbjct: 618 LFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSV 677
Query: 1132 DQENIHSL 1139
+ N+H++
Sbjct: 678 EIRNLHNV 685
>AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein.
Length = 1416
Score = 61.3 bits (142), Expect = 2e-08
Identities = 125/632 (19%), Positives = 262/632 (41%), Gaps = 54/632 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+ + + +I ++E VE+++++ +L ++ +LQ KE M E + K +++ ++
Sbjct: 560 VGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQ------KELSMCEMEREKKGRKVTEME 613
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
+ K +L ++P + F + EV + + ++ + E
Sbjct: 614 GQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKREL-E 672
Query: 513 SLNERRSELTKAED-KIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQ 571
++ + ++ K E+ + K+ Q K T K Q Q ++ +++ NK +
Sbjct: 673 NVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE-KVYLDNKLLKE 731
Query: 572 LKDNSCCPLCNRGFE-NESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDE-ILSM 629
N + N SE +N KL VT+ + ++ +L
Sbjct: 732 QAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLN--RKLLDVTQKYTEKKLEMEKLLLEN 789
Query: 630 KSLNEKITTLKDTEIP--QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM--TTAKQI 685
SL++ ++ L+ +P + EK I+ + + I L + + E+ E ++K+ T++
Sbjct: 790 DSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENT 849
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ M ++Y+ K E VK D TL + +D K+K +
Sbjct: 850 NLKKMMSNQYVP-----VKTHEEVKMTLND-----TLAKTNRELLDVKKKFEDINQEFVK 899
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+ K + L+ + + K E ++ + + +L +S +++Q
Sbjct: 900 IKDKNEILKRNLE---NTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKG 956
Query: 806 XXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI-----QQ 860
I V L +I+A+ + + ++ I+ A I E K K+ + E+ +Q
Sbjct: 957 QEEI----VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQ 1012
Query: 861 HKKKNV-PREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL 919
+K +V E++K ++ NDKL +K+I T ++ L K ++ + R D+
Sbjct: 1013 TQKYSVSEEEVKKNKQENDKL---KKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDE-- 1067
Query: 920 CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKK 979
L K D++ + + EKL EE ++ S I+ L Q++ + LKK
Sbjct: 1068 -LNKQLKDLSQKYTEVKNVKEKL----VEENAKQTSEILAVQNLLQKQHVPLEQVEALKK 1122
Query: 980 SLKGFRNELE---KSLSKDIEKKFREKMYELH 1008
SL G L+ KS+ + EK+ ++ + +LH
Sbjct: 1123 SLNGTIENLKEELKSMQRCYEKE-QQTVTKLH 1153
Score = 56.4 bits (130), Expect = 6e-07
Identities = 122/689 (17%), Positives = 284/689 (41%), Gaps = 52/689 (7%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+NE K + + E+E ++ +I +L+++ +K K + +++K +E + + K+
Sbjct: 642 EVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAK--LAQHVKPEEHEQV------KSR 693
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L + G + +K +T+ + E +E + ++ ++E
Sbjct: 694 LEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSE-- 751
Query: 519 SELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCC 578
++ K+ D I + DVT KYT +KL+ E+ +L++ ++K +L+
Sbjct: 752 -DMKKSHDAIIDDLNRKLLDVT-QKYTE--KKLEMEKLLLENDS--LSKDVSRLETVFVP 805
Query: 579 PLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSL--NEKI 636
P ++E E + +K ED ++ A E ++K + N+ +
Sbjct: 806 P-----EKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYV 860
Query: 637 TTLKDTEIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ-IHGDMPMLDR 694
E+ L + + ++ + + E+I ++ + K K+ + +
Sbjct: 861 PVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKA 920
Query: 695 YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+ K ++ + V +A ++ +++I TL +K +K+L+
Sbjct: 921 EYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRK--GQEEIVTLHAEIKAQKKELDTIQ 978
Query: 755 KKLQTLYEKKTKAKE---ELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
+ ++ Y +E + T+K+++D ++ E+++K S+ +
Sbjct: 979 ECIKVKYAPIVSFEECERKFKATEKELKDQLS-EQTQKYSVSE--EEVKKNKQENDKLKK 1035
Query: 812 LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREME 871
L++ + KT ++ ++ ++ A S ++ + E++ K+K V +
Sbjct: 1036 EIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK 1095
Query: 872 KIQE--ANDKLMEKQ----KQIMTDRQVLTKKIDTLKDEI-AKQEVYKRDLDDNLCLRKA 924
+ E A L++KQ +Q+ ++ L I+ LK+E+ + Q Y++ + + K
Sbjct: 1096 QTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEK---EQQTVTKL 1152
Query: 925 QTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
+ N + L E L +E EKE IIK L +++ E + E+ K
Sbjct: 1153 HQLLENQKNSSVPLAEHL---QIKEAFEKEVGIIK-ASLREKEEESQNKMEEVSKLQSEV 1208
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIR 1044
+N K K +E + ++ +L KA D+ +L++ L +R+ E ++
Sbjct: 1209 QN--TKQALKKLETR---EVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLH 1263
Query: 1045 ELWRKIYRGNDIDYIEIKTEGNLTVESER 1073
++I ++ + + E + + ER
Sbjct: 1264 AKKKEISAKDEKELLHFSIEQEIKDQKER 1292
Score = 46.8 bits (106), Expect = 5e-04
Identities = 110/591 (18%), Positives = 227/591 (38%), Gaps = 48/591 (8%)
Query: 195 KKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFI 254
K+I K Y N KLL+ A + + K K + K + I ++ + ++ +
Sbjct: 717 KEIEKVYLDN-KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKY 775
Query: 255 LLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQK 314
+ EK+ N+ + + ++ +E + E+ E + + LK K
Sbjct: 776 TEKKLEMEKLLLENDSL--SKDVSRLETV--FVPPEKHEKEIIALKSNIVELKKQLSELK 831
Query: 315 SQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXX 374
+ E+++K E + + + N+
Sbjct: 832 KKCGEDQEKIHALTSE-NTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKF 890
Query: 375 XXXXXXXXXHKQAENEL---NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL 431
K +NE+ N+E Q +I + ++ ++E +M LSQ + K+Q A+
Sbjct: 891 EDINQEFVKIKD-KNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAE- 948
Query: 432 KEKEMIEENLKTKEKQLIVLKNKHKTALMEL--LGNVPEKDFAVTINKFECEVRNEVXXX 489
I N + +++++ L + K EL + + +A ++ ECE + +
Sbjct: 949 -----ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEK 1003
Query: 490 XXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTV 548
E +K+ S++E + K E DK+ K T D L T +
Sbjct: 1004 ELKDQLS-------EQTQKY---SVSEEEVKKNKQENDKLKKEIFTLQKD--LRDKTVLI 1051
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
EK + + L +NK QLKD S + + + V
Sbjct: 1052 EKSHEMERALSRKTDELNK---QLKDLS--QKYTEVKNVKEKLVEENAKQTSEILAVQNL 1106
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
L+K L++ A K KSLN I LK+ E+ +++ + L++ +E
Sbjct: 1107 LQKQHVPLEQVEALK------KSLNGTIENLKE-ELKSMQRCYEKEQQTVTKLHQLLENQ 1159
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDV-DSEMTLDVAT 726
S + + + + ++ ++ ++E + ++ K E V + +V +++ L
Sbjct: 1160 KNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLE 1219
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
++V K ++ ++T ++++ N+KL L K + EE+L+ +KK
Sbjct: 1220 TREVVDLSKYKATKSDLET---QISSLNEKLANLNRKYEEVCEEVLHAKKK 1267
Score = 40.3 bits (90), Expect = 0.041
Identities = 79/417 (18%), Positives = 180/417 (43%), Gaps = 42/417 (10%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIEENLKTKEKQLI 449
++ EEC+++ EK + + ++ E +QK + +++ K K E + +++ + T +K L
Sbjct: 989 VSFEECERKFKATEK---ELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDL- 1044
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+ KT L+E + +++ E+ ++ + K
Sbjct: 1045 ----RDKTVLIE-----KSHEMERALSRKTDELNKQLKDLSQKYTEVK------NVKEKL 1089
Query: 510 IRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDE----QNVLQSSMFI 564
+ E+ + SE+ ++ + K + + T+E L++E Q +
Sbjct: 1090 VEENAKQT-SEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQT 1148
Query: 565 INKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
+ K L++ NS PL E+ ++ K E+ ++ S
Sbjct: 1149 VTKLHQLLENQKNSSVPLA----EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKL 1204
Query: 623 KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTA 682
+ E+ + K +K+ T + ++ + + D++TQI +LNE + + E +++ A
Sbjct: 1205 QSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHA 1264
Query: 683 KQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCG---DVDSEMTLDV-ATAKQVDFK-QKIS 737
K+ ++ D ++ ++ + KE+C +E+ + +AKQ++ K KI+
Sbjct: 1265 KK--KEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKIT 1322
Query: 738 TLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT-QKKVQDI-VNLEESKKQLQ 792
L N V+ ++ LN ++ T TK + +L++T Q +V+ + L ++ +Q Q
Sbjct: 1323 ELLNDVERLKQALNGLSQLTYT-SGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQ 1378
Score = 35.1 bits (77), Expect = 1.5
Identities = 49/269 (18%), Positives = 126/269 (46%), Gaps = 25/269 (9%)
Query: 72 VNRSTEVLGQVKLKIVNAKD---KQLEVTRSM---KVTALAKKKTKFQTLDSFLSTVDES 125
V + E + Q +KI + + + LE T++ + +LA+ + K +L + V +S
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 126 GKTKDVSSRCADLDIL-MHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERF------ 178
+ R +I+ +H E+ K L+++ C + + P+ ++ + +F
Sbjct: 946 NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA-PIVSFEECERKFKATEKE 1004
Query: 179 --DEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKE 235
D++ + KYS + +KK +++ + K + ++ K +E S++ + +++
Sbjct: 1005 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 1064
Query: 236 EEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQ--TNEEAE 293
+++ + +Y + +EK+ + N + +T++I ++N+ + Q E+ E
Sbjct: 1065 TDELNKQLKDLSQKYTEV----KNVKEKLVEENAK--QTSEILAVQNLLQKQHVPLEQVE 1118
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEK 322
K++ +E+LK + K + ++E++
Sbjct: 1119 ALKKSLNGTIENLKEELKSMQRCYEKEQQ 1147
Score = 34.7 bits (76), Expect = 2.0
Identities = 27/152 (17%), Positives = 72/152 (47%), Gaps = 18/152 (11%)
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
+ ++ H++++ + ++ ++ N+ L E+ ++I ++++L K++ L+ ++ ++ + D
Sbjct: 283 EVNVKSHQREH--QNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADD 340
Query: 915 LDDNLCLRKAQTDITNWQKQDDE-------LNEKLNGINKEEL-------NEKESLIIKQ 960
L+ K ++ + +KQ +E L + + L N KE +++KQ
Sbjct: 341 LESER--EKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQ 398
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
+++ ++CT + LE SL
Sbjct: 399 GQMYMADSQCTSPGIPAHMQSRSMLRPLELSL 430
>AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein.
Length = 1416
Score = 61.3 bits (142), Expect = 2e-08
Identities = 125/632 (19%), Positives = 262/632 (41%), Gaps = 54/632 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+ + + +I ++E VE+++++ +L ++ +LQ KE M E + K +++ ++
Sbjct: 560 VGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQ------KELSMCEMEREKKGRKVTEME 613
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
+ K +L ++P + F + EV + + ++ + E
Sbjct: 614 GQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIRQLKREL-E 672
Query: 513 SLNERRSELTKAED-KIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQ 571
++ + ++ K E+ + K+ Q K T K Q Q ++ +++ NK +
Sbjct: 673 NVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIE-KVYLDNKLLKE 731
Query: 572 LKDNSCCPLCNRGFE-NESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDE-ILSM 629
N + N SE +N KL VT+ + ++ +L
Sbjct: 732 QAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLN--RKLLDVTQKYTEKKLEMEKLLLEN 789
Query: 630 KSLNEKITTLKDTEIP--QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM--TTAKQI 685
SL++ ++ L+ +P + EK I+ + + I L + + E+ E ++K+ T++
Sbjct: 790 DSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENT 849
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ M ++Y+ K E VK D TL + +D K+K +
Sbjct: 850 NLKKMMSNQYVP-----VKTHEEVKMTLND-----TLAKTNRELLDVKKKFEDINQEFVK 899
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+ K + L+ + + K E ++ + + +L +S +++Q
Sbjct: 900 IKDKNEILKRNLE---NTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKG 956
Query: 806 XXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI-----QQ 860
I V L +I+A+ + + ++ I+ A I E K K+ + E+ +Q
Sbjct: 957 QEEI----VTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQ 1012
Query: 861 HKKKNV-PREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL 919
+K +V E++K ++ NDKL +K+I T ++ L K ++ + R D+
Sbjct: 1013 TQKYSVSEEEVKKNKQENDKL---KKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDE-- 1067
Query: 920 CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKK 979
L K D++ + + EKL EE ++ S I+ L Q++ + LKK
Sbjct: 1068 -LNKQLKDLSQKYTEVKNVKEKL----VEENAKQTSEILAVQNLLQKQHVPLEQVEALKK 1122
Query: 980 SLKGFRNELE---KSLSKDIEKKFREKMYELH 1008
SL G L+ KS+ + EK+ ++ + +LH
Sbjct: 1123 SLNGTIENLKEELKSMQRCYEKE-QQTVTKLH 1153
Score = 56.4 bits (130), Expect = 6e-07
Identities = 122/689 (17%), Positives = 284/689 (41%), Gaps = 52/689 (7%)
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
E+NE K + + E+E ++ +I +L+++ +K K + +++K +E + + K+
Sbjct: 642 EVNEKAKKLVEMEREHEKSLSEIRQLKRELENVKAK--LAQHVKPEEHEQV------KSR 693
Query: 459 LMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERR 518
L + G + +K +T+ + E +E + ++ ++E
Sbjct: 694 LEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSE-- 751
Query: 519 SELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCC 578
++ K+ D I + DVT KYT +KL+ E+ +L++ ++K +L+
Sbjct: 752 -DMKKSHDAIIDDLNRKLLDVT-QKYTE--KKLEMEKLLLENDS--LSKDVSRLETVFVP 805
Query: 579 PLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSL--NEKI 636
P ++E E + +K ED ++ A E ++K + N+ +
Sbjct: 806 P-----EKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYV 860
Query: 637 TTLKDTEIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ-IHGDMPMLDR 694
E+ L + + ++ + + E+I ++ + K K+ + +
Sbjct: 861 PVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKA 920
Query: 695 YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+ K ++ + V +A ++ +++I TL +K +K+L+
Sbjct: 921 EYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRK--GQEEIVTLHAEIKAQKKELDTIQ 978
Query: 755 KKLQTLYEKKTKAKE---ELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
+ ++ Y +E + T+K+++D ++ E+++K S+ +
Sbjct: 979 ECIKVKYAPIVSFEECERKFKATEKELKDQLS-EQTQKYSVSE--EEVKKNKQENDKLKK 1035
Query: 812 LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREME 871
L++ + KT ++ ++ ++ A S ++ + E++ K+K V +
Sbjct: 1036 EIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTEVKNVKEKLVEENAK 1095
Query: 872 KIQE--ANDKLMEKQ----KQIMTDRQVLTKKIDTLKDEI-AKQEVYKRDLDDNLCLRKA 924
+ E A L++KQ +Q+ ++ L I+ LK+E+ + Q Y++ + + K
Sbjct: 1096 QTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEK---EQQTVTKL 1152
Query: 925 QTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
+ N + L E L +E EKE IIK L +++ E + E+ K
Sbjct: 1153 HQLLENQKNSSVPLAEHL---QIKEAFEKEVGIIK-ASLREKEEESQNKMEEVSKLQSEV 1208
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIR 1044
+N K K +E + ++ +L KA D+ +L++ L +R+ E ++
Sbjct: 1209 QN--TKQALKKLETR---EVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLH 1263
Query: 1045 ELWRKIYRGNDIDYIEIKTEGNLTVESER 1073
++I ++ + + E + + ER
Sbjct: 1264 AKKKEISAKDEKELLHFSIEQEIKDQKER 1292
Score = 46.8 bits (106), Expect = 5e-04
Identities = 110/591 (18%), Positives = 227/591 (38%), Gaps = 48/591 (8%)
Query: 195 KKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFI 254
K+I K Y N KLL+ A + + K K + K + I ++ + ++ +
Sbjct: 717 KEIEKVYLDN-KLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKY 775
Query: 255 LLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQK 314
+ EK+ N+ + + ++ +E + E+ E + + LK K
Sbjct: 776 TEKKLEMEKLLLENDSL--SKDVSRLETV--FVPPEKHEKEIIALKSNIVELKKQLSELK 831
Query: 315 SQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXX 374
+ E+++K E + + + N+
Sbjct: 832 KKCGEDQEKIHALTSE-NTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKF 890
Query: 375 XXXXXXXXXHKQAENEL---NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKL 431
K +NE+ N+E Q +I + ++ ++E +M LSQ + K+Q A+
Sbjct: 891 EDINQEFVKIKD-KNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAE- 948
Query: 432 KEKEMIEENLKTKEKQLIVLKNKHKTALMEL--LGNVPEKDFAVTINKFECEVRNEVXXX 489
I N + +++++ L + K EL + + +A ++ ECE + +
Sbjct: 949 -----ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEK 1003
Query: 490 XXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTV 548
E +K+ S++E + K E DK+ K T D L T +
Sbjct: 1004 ELKDQLS-------EQTQKY---SVSEEEVKKNKQENDKLKKEIFTLQKD--LRDKTVLI 1051
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
EK + + L +NK QLKD S + + + V
Sbjct: 1052 EKSHEMERALSRKTDELNK---QLKDLS--QKYTEVKNVKEKLVEENAKQTSEILAVQNL 1106
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
L+K L++ A K KSLN I LK+ E+ +++ + L++ +E
Sbjct: 1107 LQKQHVPLEQVEALK------KSLNGTIENLKE-ELKSMQRCYEKEQQTVTKLHQLLENQ 1159
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTK-KFEAVKEQCGDV-DSEMTLDVAT 726
S + + + + ++ ++ ++E + ++ K E V + +V +++ L
Sbjct: 1160 KNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKLQSEVQNTKQALKKLE 1219
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
++V K ++ ++T ++++ N+KL L K + EE+L+ +KK
Sbjct: 1220 TREVVDLSKYKATKSDLET---QISSLNEKLANLNRKYEEVCEEVLHAKKK 1267
Score = 40.3 bits (90), Expect = 0.041
Identities = 79/417 (18%), Positives = 180/417 (43%), Gaps = 42/417 (10%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIEENLKTKEKQLI 449
++ EEC+++ EK + + ++ E +QK + +++ K K E + +++ + T +K L
Sbjct: 989 VSFEECERKFKATEK---ELKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDL- 1044
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+ KT L+E + +++ E+ ++ + K
Sbjct: 1045 ----RDKTVLIE-----KSHEMERALSRKTDELNKQLKDLSQKYTEVK------NVKEKL 1089
Query: 510 IRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDE----QNVLQSSMFI 564
+ E+ + SE+ ++ + K + + T+E L++E Q +
Sbjct: 1090 VEENAKQT-SEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQT 1148
Query: 565 INKYKGQLKD--NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
+ K L++ NS PL E+ ++ K E+ ++ S
Sbjct: 1149 VTKLHQLLENQKNSSVPLA----EHLQIKEAFEKEVGIIKASLREKEEESQNKMEEVSKL 1204
Query: 623 KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTA 682
+ E+ + K +K+ T + ++ + + D++TQI +LNE + + E +++ A
Sbjct: 1205 QSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHA 1264
Query: 683 KQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCG---DVDSEMTLDV-ATAKQVDFK-QKIS 737
K+ ++ D ++ ++ + KE+C +E+ + +AKQ++ K KI+
Sbjct: 1265 KK--KEISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKIT 1322
Query: 738 TLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT-QKKVQDI-VNLEESKKQLQ 792
L N V+ ++ LN ++ T TK + +L++T Q +V+ + L ++ +Q Q
Sbjct: 1323 ELLNDVERLKQALNGLSQLTYT-SGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQ 1378
Score = 35.1 bits (77), Expect = 1.5
Identities = 49/269 (18%), Positives = 126/269 (46%), Gaps = 25/269 (9%)
Query: 72 VNRSTEVLGQVKLKIVNAKD---KQLEVTRSM---KVTALAKKKTKFQTLDSFLSTVDES 125
V + E + Q +KI + + + LE T++ + +LA+ + K +L + V +S
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 126 GKTKDVSSRCADLDIL-MHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERF------ 178
+ R +I+ +H E+ K L+++ C + + P+ ++ + +F
Sbjct: 946 NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA-PIVSFEECERKFKATEKE 1004
Query: 179 --DEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKE 235
D++ + KYS + +KK +++ + K + ++ K +E S++ + +++
Sbjct: 1005 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 1064
Query: 236 EEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQ--TNEEAE 293
+++ + +Y + +EK+ + N + +T++I ++N+ + Q E+ E
Sbjct: 1065 TDELNKQLKDLSQKYTEV----KNVKEKLVEENAK--QTSEILAVQNLLQKQHVPLEQVE 1118
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEK 322
K++ +E+LK + K + ++E++
Sbjct: 1119 ALKKSLNGTIENLKEELKSMQRCYEKEQQ 1147
Score = 34.7 bits (76), Expect = 2.0
Identities = 27/152 (17%), Positives = 72/152 (47%), Gaps = 18/152 (11%)
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
+ ++ H++++ + ++ ++ N+ L E+ ++I ++++L K++ L+ ++ ++ + D
Sbjct: 283 EVNVKSHQREH--QNIQDLEIENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADD 340
Query: 915 LDDNLCLRKAQTDITNWQKQDDE-------LNEKLNGINKEEL-------NEKESLIIKQ 960
L+ K ++ + +KQ +E L + + L N KE +++KQ
Sbjct: 341 LESER--EKLKSLLAAKEKQHEESLRTIEALKNRFKYFESDHLGSGSHFSNRKEDMLLKQ 398
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
+++ ++CT + LE SL
Sbjct: 399 GQMYMADSQCTSPGIPAHMQSRSMLRPLELSL 430
>Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated
microtubule-binding protein protein.
Length = 1979
Score = 60.9 bits (141), Expect = 3e-08
Identities = 196/1014 (19%), Positives = 410/1014 (40%), Gaps = 94/1014 (9%)
Query: 71 KVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKD 130
K+N EV+ + ++ D +L +++ AK++ Q++ + + E +
Sbjct: 447 KLNNEYEVIKSTATRDISL-DSELH---DLRLNLEAKEQELNQSISEKETLIAEIEELDR 502
Query: 131 VSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC 190
+ IL+ ++L + +S++ ++D + DE K+V + D+ D K D
Sbjct: 503 QNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLN---DEKKRVHQLEDDKMDITKELD- 558
Query: 191 LDRLKKIRKDYAQN-LKLL-ENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEI 248
+ + K I+ + A N L L + V+ +L S + N S KE ++ NE
Sbjct: 559 VQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEE 618
Query: 249 EYNKFI--LLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E ++ L++S NQ+ + +++ + AE+ N+ + + E N E ++ +
Sbjct: 619 ELSRIRNELMQSLNQDSNSNFKDTLLKERE-AEVRNLKQNLSELEQLN------ENLKKV 671
Query: 307 KSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQS 366
D K++ + + + ++EC +G+ Q ++ A +
Sbjct: 672 AFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKR 731
Query: 367 XXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK 426
A N LN Q E K ++ + E+ EL + I Q
Sbjct: 732 LLEEANKYEKTIEELS---NARN-LNTSALQLEHEHLIKLNQKKDMEIAELKKNIE--QM 785
Query: 427 QTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVR-NE 485
T + K+++ +L+ ++KQL L NK K +E L K ++K+ +R NE
Sbjct: 786 DTDHKETKDVLSSSLE-EQKQLTQLINK-KEIFIEKLKERSSK-LQEELDKYSQALRKNE 842
Query: 486 VXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK----AEDKIYKACGTQPYDVTL 541
+ ++ E H++E L R E ++ A+ K + +V
Sbjct: 843 ILRQTIEEKDRSLGS--MKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEV-- 898
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX 601
S+ T E L++E Q + N+ K QL + E +
Sbjct: 899 SQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSL----------QEQKKEMDEFRYQHE 948
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDV--DTQIK 659
MN Q K +EI S++ E+I T E ++ D+ +T+++
Sbjct: 949 QMNAT--------HTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQ 1000
Query: 660 TLN--ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAV-KEQCGDV 716
+LN E+ +S E E+ + K+ ++ +L+ ++ ++TK+ + + K++ G +
Sbjct: 1001 SLNIENGSEKHDLSKAETERLVKGIKERELEIKLLN---EKNISLTKQIDQLSKDEVGKL 1057
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAH---NKKLQTLYEKKTKAKEELLN 773
+ + + + ++ V Q++L A+ +K+ + +KT+ L
Sbjct: 1058 TQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKT 1117
Query: 774 TQKKVQDIVNLEESKK-QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
K+ DIV +E+ +LQ + + +E I+ + ++R
Sbjct: 1118 EYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDM------FRETIQNLSRIIREKDI 1171
Query: 833 LIEAGSAYIAKVEVAFNKVKSLDAE---IQQHKKKNVPREMEKIQEANDKLMEKQKQIMT 889
I+A S + +A + S E + H+ + + +E +K+++ K+ E ++Q+MT
Sbjct: 1172 EIDALSQKCQTL-LAVLQTSSTGNEAGGVNSHQFEELLQERDKLKQQVKKMEEWKQQVMT 1230
Query: 890 DRQVLTKKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE 948
Q + + L++E+ + Q D D+N K Q D T + ++ KL +E
Sbjct: 1231 TVQNMQHESAQLQEELHQLQAQVLVDSDNN---SKLQVDYTGLIQSYEQNETKLKNFGQE 1287
Query: 949 ---------EL-NEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+L N K+ L+ K + Q + + + + L+ ++E+ S+ +++
Sbjct: 1288 LAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQ 1347
Query: 999 KFREKMYELHVTKAIDKDIREYAVALDKCL---MEFHREKMENINMIIRELWRK 1049
+ E L A + ++E L + E R++ E + I++L K
Sbjct: 1348 ELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEK 1401
Score = 49.6 bits (113), Expect = 7e-05
Identities = 82/449 (18%), Positives = 204/449 (45%), Gaps = 46/449 (10%)
Query: 642 TEIPQLEKRIVDV-DTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGD-MPMLDRYIQEI 699
+EI +L+ I ++ + + +++ E+++ +QK+T + H + + + I+E+
Sbjct: 209 SEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEEL 268
Query: 700 KTVTKKFEA--VKEQCGDV-DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK 756
+ + ++ + ++ + + + T+ V ++V+ +K+ L +++K KKL++
Sbjct: 269 ENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAEND 328
Query: 757 LQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVAL 816
L + ++E LN +K+ + E + L+ +C +T E L
Sbjct: 329 RDIL-----RREQEQLNVEKR-----QIMEECENLKLECSKLQPSAVKQSDTMTEKERIL 378
Query: 817 KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEA 876
+ + EV R + L +A + I ++ + N+ SL + + K + +E +++
Sbjct: 379 AQSASVE-EVFRLQQALSDAENE-IMRLS-SLNQDNSLAEDNLKLKMR-----IEVLEKE 430
Query: 877 NDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD 936
L ++++++ L + + +K + +L D LR N + ++
Sbjct: 431 KSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHD---LR------LNLEAKEQ 481
Query: 937 ELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
ELN+ ++ EKE+LI + +L +Q E T + +K L +NE + +SK +
Sbjct: 482 ELNQSIS--------EKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISK-L 532
Query: 997 EKKFREKMYELHVTKAIDKDI-REYAVALDKCLMEFHREKMENINMIIRELWRKIYRGND 1055
++ ++ +H + DI +E V +K + + ++++ ++L K+ N
Sbjct: 533 KQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQS--EVALNDLHLTKQKLEDKV--ENL 588
Query: 1056 IDYIEIKTEGNLTVESERRKYDYRVVQSK 1084
+D + E N++++ E + + Q++
Sbjct: 589 VDQLNKSQESNVSIQKENLELKEHIRQNE 617
Score = 35.5 bits (78), Expect = 1.2
Identities = 64/334 (19%), Positives = 141/334 (42%), Gaps = 30/334 (8%)
Query: 730 VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESK 788
+ +Q+I+ L N V + ++ QT + T ++ + K+Q+I+ L++++
Sbjct: 168 ISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQ--SEICKLQNIIKELKQNR 225
Query: 789 KQ-LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
Q + +T + +E++ E + +L++ G + + +E
Sbjct: 226 SQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGV--IETD 283
Query: 848 FNKVKSLDAEIQ--QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
+K+ + IQ Q +K ++ME++++ + +K DR +L ++ + L +
Sbjct: 284 LSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQL--NV 341
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK----LNGINKEE-------LNEKE 954
K+++ + + L K Q KQ D + EK + EE L++ E
Sbjct: 342 EKRQIMEECENLKLECSKLQPSAV---KQSDTMTEKERILAQSASVEEVFRLQQALSDAE 398
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
+ I++ + L Q + A LK ++ E EKSL +++ + + +L+ +
Sbjct: 399 NEIMRLSSLNQDNSL---AEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVI 455
Query: 1015 KDIREYAVALDKCLMEFH---REKMENINMIIRE 1045
K ++LD L + K + +N I E
Sbjct: 456 KSTATRDISLDSELHDLRLNLEAKEQELNQSISE 489
Score = 33.1 bits (72), Expect = 6.2
Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 11/107 (10%)
Query: 218 KQKELEDSYKKNTSFNKEEEKIANE--KSSNEIEYNKFILLESQN---QEKIDKRNEQIV 272
KQK++E NT+ E +++ ++ +S+ E+E + LLES++ +E + + +
Sbjct: 1554 KQKQME-----NTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAK 1608
Query: 273 ETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADE 319
K+ +E V ++ ENA+ +VESL+ V Q DE
Sbjct: 1609 LRKKVTVLEEKL-VSSSNAMENASHQASVQVESLQEQLNVVSKQRDE 1654
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 60.9 bits (141), Expect = 3e-08
Identities = 125/639 (19%), Positives = 262/639 (41%), Gaps = 50/639 (7%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEM-IEENLKTKEKQLIVL 451
+E E E + ++E+ +L + I KL+ + ++K++ I E LK +E++ L
Sbjct: 2189 LEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSL 2248
Query: 452 KNKHKTALMELLGNVPEKDFAVTI---NKFECE-VRNEVXXXXXXXXXXXXXXXXLEAER 507
K+K + EL + ++ + +K E E ++ ++ L +E+
Sbjct: 2249 KDKVENLERELQMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEK 2308
Query: 508 KHIRESLNERRSELTKAEDKI--YKACGTQPYDVTLS---KYTTTVEKLQDEQNVLQSSM 562
+++ + + E++ +L++ + + +K+ + + + T VE LQ++ L ++
Sbjct: 2309 ENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2368
Query: 563 FIINKYKGQLK--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS 620
+ + +K + S P + + L+++ E A
Sbjct: 2369 AALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHAD 2428
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMT 680
K + +++ E T ++ + E +++TL +E +T SL E +
Sbjct: 2429 LLKGRVENLERELEIARTNQEHAALEAENS----KGEVETLKAKIEGMTQSLRGLELDVV 2484
Query: 681 TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLR 740
T + D L +Q+ + + E + ++ L ++V K+K ST
Sbjct: 2485 TIRSEKED---LTNELQKEQERISELEIINSSFENI-----LQEKEQEKVQMKEKSSTAM 2536
Query: 741 NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXX 800
++T K+LN L E KAKE+ L++Q + LE K QL
Sbjct: 2537 EMLQTQLKELNERVAALHNDQEA-CKAKEQNLSSQVEC-----LELEKAQLLQGLDEAKN 2590
Query: 801 XXXXXXXAITPLEVAL---KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
++ L + K+K+E K E + R ++ I+ E +K+ ++ E
Sbjct: 2591 NYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQ-------DQEQLVSKLSQVEGE 2643
Query: 858 IQQHKKKNVP-REME-KIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
Q K++N+ R + ++++ L K + +VL L++E+ ++ K
Sbjct: 2644 HQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSF 2703
Query: 916 DDNLCLRKA-----QTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ-QKAE 969
+ + A Q ++ ++ EL E+L+G K L + L++++ K + Q E
Sbjct: 2704 VEKVNKMTAKETELQREMHEMAQKTAELQEELSG-EKNRLAGELQLLLEEIKSSKDQLKE 2762
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
T SELKKSL + + K + ++ E LH
Sbjct: 2763 LTLENSELKKSLDCMHKDQVEKEGK-VREEIAEYQLRLH 2800
Score = 56.4 bits (130), Expect = 6e-07
Identities = 116/632 (18%), Positives = 263/632 (41%), Gaps = 46/632 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK--QTAKLKEKEMIEENLK 442
+QA+N N+ Q E+++ +Q E ++E QK+ + ++ Q +++KE E+ +++
Sbjct: 426 QQAKNMHNV--LQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENEL-RRSME 482
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRNEVXXXXXXXXXXXXXXX 501
+K+ +LK+ + E+ E K+ +N+ + N
Sbjct: 483 EMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQ----NFAEEMKAKNTSQETMLR 538
Query: 502 XLEAERKHIRESLNERRSELTKAEDKIYKACGT---QPYDVTLSKYTTTVEKLQDEQNVL 558
L+ + SL + +L A+ + + C + + + + + K + E L
Sbjct: 539 DLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKAL 598
Query: 559 QSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
S++ + K +LK+ C + ENE N+ K+ + L+
Sbjct: 599 LSALELKKKEYEELKEEKTLFSCWKS-ENEK----LLTQMESEKENLQSKINHLETCLKT 653
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
K E NE++ TL + + L I ++ + + + VE ++ +E +QK
Sbjct: 654 QQIKSHEY------NERVRTL-EMDRENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQK 706
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q H ++ + +T + E ++ + + +E+ +D Q D + +
Sbjct: 707 AEFSDQKH--QKEIENMCLKTSQLTGQVEDLEHKLQLLSNEI-MDKDRCYQ-DLHAEYES 762
Query: 739 LRNRVKTTQKKL--NAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCX 796
LR+ +K+ L N +++ ++++ N + Q + E S+ +L++D
Sbjct: 763 LRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANIIGE-QGSMPSERSECRLEAD-- 819
Query: 797 XXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDA 856
+ LE +L+ + + +++ ++ +L++ + A +S A
Sbjct: 820 QSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVA 879
Query: 857 EIQQHKKK---NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
E Q K + + E L K+K++ Q+L K++T + EI + +
Sbjct: 880 ETSQRISKLQEDTSAHQNVVAETLSALENKEKEL----QLLNDKVETEQAEIQELKKSNH 935
Query: 914 DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAECTG 972
L+D+L + ++ + +K++ LN EEL ++ + + L Q+K
Sbjct: 936 LLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMN--- 992
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
L + +S + +E EKS+S+ ++ +EK+
Sbjct: 993 -LIQKSESFANYIDEREKSISELSDQYKQEKL 1023
Score = 56.4 bits (130), Expect = 6e-07
Identities = 140/764 (18%), Positives = 313/764 (40%), Gaps = 89/764 (11%)
Query: 181 IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIA 240
I DA+ ++ LK ++ A++LK+ E T++++++ L ++ E +K+
Sbjct: 2270 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLL 2329
Query: 241 NE-KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK-IAEIENITEVQTNEEAENATKT 298
+ KS E + I ++ +++ ++ Q+ E + +A + E+ + E +
Sbjct: 2330 SSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIM--KATEQSLDP 2387
Query: 299 ILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXX 358
+E+ L++ + +++ + +EKK + + +
Sbjct: 2388 PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL------ 2441
Query: 359 DITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELS 418
+I NQ K IE Q + E V E ++L+
Sbjct: 2442 EIARTNQEHAALEAENSKGEVETLKAK-------IEGMTQSLRGLELDVVTIRSEKEDLT 2494
Query: 419 QKITKLQKQTAKLKEKEMIEEN-LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINK 477
++ K Q++ ++L+ EN L+ KE++ + +K K TA+ L + E +N+
Sbjct: 2495 NELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKE------LNE 2548
Query: 478 FECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPY 537
+ N+ LE E+ + + L+E ++ Y
Sbjct: 2549 RVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLDEAKNN----------------Y 2592
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
V S +++++D + L+ I++ K Q++D L ++ + E E
Sbjct: 2593 IVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQE--QLVSKLSQVEGEHQLWKEQ 2650
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEIL-----SMKSLNEKITTLKDTEIPQLEKRIV 652
N+ +LE+ + LQ +A + L S K+L ++ K ++ +EK +
Sbjct: 2651 NLELR-NLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VN 2708
Query: 653 DVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
+ + L + E+ E +++++ K ++ G++ +L ++EIK+ + + +
Sbjct: 2709 KMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLL---LEEIKSSKDQLKELTL 2765
Query: 712 QCGDVDSEMTLDVATAKQVD----FKQKISTLRNRVKTTQKKLNA----HNKKLQT---L 760
+ ++ + +LD QV+ +++I+ + R+ +KK A NK+ +
Sbjct: 2766 ENSEL--KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQT 2823
Query: 761 YEKKTKAKEELLNTQKKVQDIVN----------------LEESKKQLQSDCXXXXXXXXX 804
Y +K +KEE L++QK D++ LEE KK +
Sbjct: 2824 YREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKE 2883
Query: 805 XXXAITPLEVALK--EKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK 862
A +++ +K +++E + E++++ ++A V KV L EI++ K
Sbjct: 2884 NERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELK 2943
Query: 863 KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
+ EK +EA D+ ++K ++ + L K + L+ ++A
Sbjct: 2944 E----TLEEKTKEA-DEYLDKYCSLLISHEKLEKAKEMLETQVA 2982
Score = 49.2 bits (112), Expect = 9e-05
Identities = 92/463 (19%), Positives = 214/463 (46%), Gaps = 59/463 (12%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTL-KDTEIP-----QLEKRIVDVDTQIKT 660
++++ TE LQ S+ E+L K+ L EK+ +L KD++ +LE +I ++ + +
Sbjct: 2104 EVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQIAQLNKEKEL 2163
Query: 661 LNETVEEITMSLIEPE-QKMTTAKQIH------GDMPM-LDRYIQEIKTVTKKFEAVKEQ 712
L + E + L E + +K+ +K + G+ + L +E+ + + E ++ +
Sbjct: 2164 LVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVR 2223
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL--NAHNKKLQTLYEKKTKAKEE 770
+ D + L +A K + +++ +L+++V+ +++L + N++L L + +KA+ E
Sbjct: 2224 I-EADEKKQLHIAE-KLKERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVE 2281
Query: 771 LLNTQKKVQ---------DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE 821
L TQ + D+V L K+ L ++ + L+EK +
Sbjct: 2282 TLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQ 2341
Query: 822 AKTEVVRRN-----------RDLIEAGSAYIAKVEVAFNKVKSLDAEI-QQHKKKNVPRE 869
A+ ++ + ++L EA +A E+ +SLD I ++H+ +N +
Sbjct: 2342 AEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRNSIEK 2401
Query: 870 MEKIQEANDK----LMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD-NLCLRKA 924
+ EA++K ++++ K+ +L +++ L+ E+ E+ + + + L +
Sbjct: 2402 LRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL---EIARTNQEHAALEAENS 2458
Query: 925 QTDITNWQKQDDELNEKLNGINKEEL---NEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ ++ + + + + + L G+ + + +EKE L T Q++ E +SEL+
Sbjct: 2459 KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDL----TNELQKEQE---RISELEIIN 2511
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVAL 1024
F N L++ + ++ K + + + + K++ E AL
Sbjct: 2512 SSFENILQEKEQEKVQMK-EKSSTAMEMLQTQLKELNERVAAL 2553
Score = 46.8 bits (106), Expect = 5e-04
Identities = 78/436 (17%), Positives = 174/436 (39%), Gaps = 32/436 (7%)
Query: 714 GDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLN 773
G+ S LD A+ + + KI+ L R++ +K++ K Q L + KAK EL+
Sbjct: 272 GNSSSPHLLDQLKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELI- 330
Query: 774 TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
K+++ + C + AL++K++ TE + R
Sbjct: 331 -------------EKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQ- 376
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQV 893
A SA + + K K E+ + ++ + E IQ +L ++ +Q V
Sbjct: 377 -NAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQ-MKARLTQELQQAKNMHNV 434
Query: 894 LTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEK 953
L ++D L + E + LC +A+ Q +++EL + + KE K
Sbjct: 435 LQAELDKLTSVKQQLENNLEEFKQKLC--RAEQAFQASQIKENELRRSMEEMKKENNLLK 492
Query: 954 ESLIIKQTKLFQQKAE------CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYEL 1007
K ++ +AE C + +K +N ++++ +D+++K ++ L
Sbjct: 493 SHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKA-KNTSQETMLRDLQEKINQQENSL 551
Query: 1008 HVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGND-IDYIEIKTEGN 1066
+ K + + + D C + +++ +I + +L + + +E+K +
Sbjct: 552 TLEK-LKLAVADLEKQRD-CSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEY 609
Query: 1067 LTVESERRKYD-YRVVQSK--NGVEIDMRGRCSAGQKVLACLIIRLALAETFSSRFGILA 1123
++ E+ + ++ K +E + S + CL + + ++ R L
Sbjct: 610 EELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLE 669
Query: 1124 LDEPTTNLDQENIHSL 1139
+D +++ N+H++
Sbjct: 670 MDRENLSVEIRNLHNV 685
Score = 46.0 bits (104), Expect = 8e-04
Identities = 102/475 (21%), Positives = 203/475 (42%), Gaps = 55/475 (11%)
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K + ++ ++ ++ QLEK V++ + K LN+ +E+ + + +Q T + +
Sbjct: 306 KEMKGQVNKFQELQL-QLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKL 364
Query: 690 PMLDRYI----QEIKTVTKKFE-AVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK 744
L + Q ++ E +KE+ + E++ + + +D ++ I +
Sbjct: 365 KKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLD-QECIQMKARLTQ 423
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q+ N HN LQ +K T K++L N NLEE K++L
Sbjct: 424 ELQQAKNMHN-VLQAELDKLTSVKQQLEN---------NLEEFKQKLCRAEQAFQASQIK 473
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
+E KE K+ ++ R++ A + ++ N+ ++ E+ K K
Sbjct: 474 ENELRRSMEEMKKENNLLKSHSEQKAREVCHL-EAELKNIKQCLNQSQNFAEEM---KAK 529
Query: 865 NVPRE------MEKI-QEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD 917
N +E EKI Q+ N +EK K + D L K+ D +D + K+E + L+D
Sbjct: 530 NTSQETMLRDLQEKINQQENSLTLEKLKLAVAD---LEKQRDCSQDLLKKREHHIEQLND 586
Query: 918 NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTK-LFQ-QKAECTGALS 975
L K + E L+ + EL +KE +K+ K LF K+E L+
Sbjct: 587 KL------------SKTEKESKALLSAL---ELKKKEYEELKEEKTLFSCWKSENEKLLT 631
Query: 976 EL---KKSLKGFRNELEKSLSKDIEK--KFREKMYELHVTKA-IDKDIREYAVALDKCLM 1029
++ K++L+ N LE L K ++ E++ L + + + +IR LD +
Sbjct: 632 QMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSV 691
Query: 1030 EFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQSK 1084
E +K+ + + + + +I+ + +KT LT + E ++ +++ ++
Sbjct: 692 EVETQKLAYMELQQKAEFSDQKHQKEIENMCLKT-SQLTGQVEDLEHKLQLLSNE 745
>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
Length = 1843
Score = 60.9 bits (141), Expect = 3e-08
Identities = 177/909 (19%), Positives = 340/909 (37%), Gaps = 61/909 (6%)
Query: 170 EGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKN 229
E + KER + D + Y ++ LK+ + + +LE+ +A+ +L + K+N
Sbjct: 328 EVSRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN 384
Query: 230 TSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIA-EIENITEVQT 288
+ K+ + + +++ K L +N + + + E+ + E+E I+ +T
Sbjct: 385 LQL---KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS--RT 439
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXX 348
+E +E K++ +V L S ++ ++ K V+E R+
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKT---VEELRTTVDSVEGNASKILKM 496
Query: 349 XXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEKAV 407
N+ K+ A+ E IE ++ K +
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
EQ + +++ + + + +A+ + K++ +EN E + + K + +E
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHES---IKETSSKLSKIEFEKRQI 613
Query: 468 EKDFAVTINKFEC--EVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE 525
+K+ K E E+ NE+ L+ + I E+L + SEL +
Sbjct: 614 KKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI-EALEQENSELEREN 672
Query: 526 DKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSC----CPLC 581
K+ K + T +E L+ E + L + + LK S L
Sbjct: 673 RKLKKTLD------SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE 726
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTE--DLQRASAKKDEILSMKSLNEKITTL 639
N+ E+E E +LE + D++ +K S K + + + L
Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Query: 640 KDTEIPQ--LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ 697
+D E+ L+K + ++ K L + +E E Q KQ+ + L R
Sbjct: 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL-RQQA 845
Query: 698 EIKTVTKKFEAVKEQCGDVDSE-MTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK 756
EIK T + VK G+++ E TL + ++ L K K+ K
Sbjct: 846 EIKDTTLEENNVK--IGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Query: 757 LQTLYE----KKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPL 812
L TL E +K K ++ + +K ++ + +K++L D + L
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD--EQSTDDSRYKLLESKL 961
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK 872
E LK+ +E K E + +E + Y ++ VK ++Q + + +
Sbjct: 962 ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP 1021
Query: 873 IQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE------IAKQEVYKRDLDD-NLCLRKAQ 925
D E++ Q T R++L K ++ E A+++ K L Q
Sbjct: 1022 PISGEDNKWERESQ-ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1080
Query: 926 TDITNWQKQD---DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
I Q+Q E N L N + E +L + T L Q A+ S L+ +
Sbjct: 1081 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE 1140
Query: 983 GFRNELE--KSLSKDIEKKFREKMYELHVTKAIDKD--IREYAV--ALDKCLMEFHREKM 1036
E E KSL + K EK+ LH +A + + I ++ + K L HR+
Sbjct: 1141 SVIKEREDLKSLYDSLIKD-HEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE 1199
Query: 1037 ENINMIIRE 1045
+ N ++++
Sbjct: 1200 DRYNQLLKQ 1208
>BC114620-1|AAI14621.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 60.9 bits (141), Expect = 3e-08
Identities = 86/439 (19%), Positives = 200/439 (45%), Gaps = 31/439 (7%)
Query: 661 LNETVEEITMSLIEPEQKMTTAK---QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
+ E +E+ +PE + + +I +++R EI + K+ +A+K+ V
Sbjct: 1228 VKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQ 1287
Query: 718 SEMTLDVATAKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
++ + Q D K+++++LR ++ QKK ++ + E+ + +EEL +
Sbjct: 1288 TKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVK 1347
Query: 776 KKV--QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE------KIEAKTEVV 827
++V Q++V EE + L+++ I L L+ ++E + E +
Sbjct: 1348 ERVVQQEVVRYEE-EPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEEL 1406
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ---HKKKNVPREMEKIQEANDKLMEKQ 884
R R + +++ ++ +AE ++ H +K V ++ + + L +
Sbjct: 1407 ERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQL 1466
Query: 885 KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN-EKLN 943
++ RQ+L +++TL+ ++A E K ++ + + L ++ +K D E ++L
Sbjct: 1467 EEEQHRRQLLEGELETLRRKLAALE--KAEVKEKVVL----SESVQVEKGDTEQEIQRLK 1520
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEK-SLSKD-IEKKFR 1001
+EE K L ++ ++L + +E S+ K L R E K L ++ ++ + R
Sbjct: 1521 SSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERENLQLETR 1580
Query: 1002 EKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEI 1061
E+++ +D+R VA D H ++ ++ + +L +++ + D++ E+
Sbjct: 1581 RLQSEINMAATETRDLRNMTVA-DSGTN--HDSRLWSLERELDDL-KRLSKDKDLEIDEL 1636
Query: 1062 -KTEGNLTVESERRKYDYR 1079
K G++ V+ E+R+ R
Sbjct: 1637 QKRLGSVAVKREQRENHLR 1655
Score = 41.5 bits (93), Expect = 0.018
Identities = 96/559 (17%), Positives = 229/559 (40%), Gaps = 32/559 (5%)
Query: 397 QQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHK 456
Q+++ E E Q + +++ Q++ + ++ +L+EK+ EE L + +L L+ +
Sbjct: 1049 QEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQ--EEELSFLQDKLKRLEKER- 1105
Query: 457 TALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE 516
A+ E G + K+ + + K + EV + E+ + +
Sbjct: 1106 -AMAE--GKITVKE-VLKVEK-DAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWA 1160
Query: 517 RRSELTKA--EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD 574
E K ++K+ + +P S+ +L +++ + + + Y+ +L+
Sbjct: 1161 LEEENAKVVVQEKVREI--VRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELE- 1217
Query: 575 NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI-LSMKSLN 633
L RG + E + + +L+++ E++ + + L + L
Sbjct: 1218 ----ALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLK 1273
Query: 634 EKITTLKDTEIPQLE-KRIVDVDTQIKTLNETVEEIT---MSLIEPEQKMTTAKQIHGDM 689
++I LKDT+ PQ++ K +V Q + +T EE+ L E ++K ++
Sbjct: 1274 KEIQALKDTK-PQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQ 1332
Query: 690 -PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV---ATAKQVDFK-QKISTLRNRVK 744
+ R +E+ V K V+++ + E L A A+ +D + ++I LR ++
Sbjct: 1333 EEQIARKEEELSRV--KERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELR 1390
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q++ ++L+ L ++ +E Q+ Q + LE+ + + +
Sbjct: 1391 RLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQ 1450
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
L+ ++E + + +E +A +E A K K + +E Q +K
Sbjct: 1451 QDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG 1510
Query: 865 NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKA 924
+ +E+++++ + ++ ++++ + L ++ L+ +K L + K
Sbjct: 1511 DTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREE--NHKL 1568
Query: 925 QTDITNWQKQDDELNEKLN 943
Q + N Q + L ++N
Sbjct: 1569 QLERENLQLETRRLQSEIN 1587
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 60.9 bits (141), Expect = 3e-08
Identities = 177/909 (19%), Positives = 340/909 (37%), Gaps = 61/909 (6%)
Query: 170 EGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKN 229
E + KER + D + Y ++ LK+ + + +LE+ +A+ +L + K+N
Sbjct: 328 EVSRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN 384
Query: 230 TSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIA-EIENITEVQT 288
+ K+ + + +++ K L +N + + + E+ + E+E I+ +T
Sbjct: 385 LQL---KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS--RT 439
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXX 348
+E +E K++ +V L S ++ ++ K V+E R+
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKT---VEELRTTVDSVEGNASKILKM 496
Query: 349 XXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEKAV 407
N+ K+ A+ E IE ++ K +
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
EQ + +++ + + + +A+ + K++ +EN E + + K + +E
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHES---IKETSSKLSKIEFEKRQI 613
Query: 468 EKDFAVTINKFEC--EVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE 525
+K+ K E E+ NE+ L+ + I E+L + SEL +
Sbjct: 614 KKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI-EALEQENSELEREN 672
Query: 526 DKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSC----CPLC 581
K+ K + T +E L+ E + L + + LK S L
Sbjct: 673 RKLKKTLD------SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE 726
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTE--DLQRASAKKDEILSMKSLNEKITTL 639
N+ E+E E +LE + D++ +K S K + + + L
Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Query: 640 KDTEIPQ--LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ 697
+D E+ L+K + ++ K L + +E E Q KQ+ + L R
Sbjct: 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL-RQQA 845
Query: 698 EIKTVTKKFEAVKEQCGDVDSE-MTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK 756
EIK T + VK G+++ E TL + ++ L K K+ K
Sbjct: 846 EIKDTTLEENNVK--IGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKT 903
Query: 757 LQTLYE----KKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPL 812
L TL E +K K ++ + +K ++ + +K++L D + L
Sbjct: 904 LVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHD--EQSTDDSRYKLLESKL 961
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK 872
E LK+ +E K E + +E + Y ++ VK ++Q + + +
Sbjct: 962 ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP 1021
Query: 873 IQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE------IAKQEVYKRDLDD-NLCLRKAQ 925
D E++ Q T R++L K ++ E A+++ K L Q
Sbjct: 1022 PISGEDNKWERESQ-ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1080
Query: 926 TDITNWQKQD---DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
I Q+Q E N L N + E +L + T L Q A+ S L+ +
Sbjct: 1081 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE 1140
Query: 983 GFRNELE--KSLSKDIEKKFREKMYELHVTKAIDKD--IREYAV--ALDKCLMEFHREKM 1036
E E KSL + K EK+ LH +A + + I ++ + K L HR+
Sbjct: 1141 SVIKEREDLKSLYDSLIKD-HEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE 1199
Query: 1037 ENINMIIRE 1045
+ N ++++
Sbjct: 1200 DRYNQLLKQ 1208
>AB011140-1|BAA25494.1| 1426|Homo sapiens KIAA0568 protein protein.
Length = 1426
Score = 60.9 bits (141), Expect = 3e-08
Identities = 86/439 (19%), Positives = 200/439 (45%), Gaps = 31/439 (7%)
Query: 661 LNETVEEITMSLIEPEQKMTTAK---QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
+ E +E+ +PE + + +I +++R EI + K+ +A+K+ V
Sbjct: 898 VKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQ 957
Query: 718 SEMTLDVATAKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
++ + Q D K+++++LR ++ QKK ++ + E+ + +EEL +
Sbjct: 958 TKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVK 1017
Query: 776 KKV--QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE------KIEAKTEVV 827
++V Q++V EE + L+++ I L L+ ++E + E +
Sbjct: 1018 ERVVQQEVVRYEE-EPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEEL 1076
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ---HKKKNVPREMEKIQEANDKLMEKQ 884
R R + +++ ++ +AE ++ H +K V ++ + + L +
Sbjct: 1077 ERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQL 1136
Query: 885 KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN-EKLN 943
++ RQ+L +++TL+ ++A E K ++ + + L ++ +K D E ++L
Sbjct: 1137 EEEQHRRQLLEGELETLRRKLAALE--KAEVKEKVVL----SESVQVEKGDTEQEIQRLK 1190
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEK-SLSKD-IEKKFR 1001
+EE K L ++ ++L + +E S+ K L R E K L ++ ++ + R
Sbjct: 1191 SSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERENLQLETR 1250
Query: 1002 EKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEI 1061
E+++ +D+R VA D H ++ ++ + +L +++ + D++ E+
Sbjct: 1251 RLQSEINMAATETRDLRNMTVA-DSGTN--HDSRLWSLERELDDL-KRLSKDKDLEIDEL 1306
Query: 1062 -KTEGNLTVESERRKYDYR 1079
K G++ V+ E+R+ R
Sbjct: 1307 QKRLGSVAVKREQRENHLR 1325
Score = 41.5 bits (93), Expect = 0.018
Identities = 96/559 (17%), Positives = 229/559 (40%), Gaps = 32/559 (5%)
Query: 397 QQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHK 456
Q+++ E E Q + +++ Q++ + ++ +L+EK+ EE L + +L L+ +
Sbjct: 719 QEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQ--EEELSFLQDKLKRLEKER- 775
Query: 457 TALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE 516
A+ E G + K+ + + K + EV + E+ + +
Sbjct: 776 -AMAE--GKITVKE-VLKVEK-DAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWA 830
Query: 517 RRSELTKA--EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD 574
E K ++K+ + +P S+ +L +++ + + + Y+ +L+
Sbjct: 831 LEEENAKVVVQEKVREI--VRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELE- 887
Query: 575 NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI-LSMKSLN 633
L RG + E + + +L+++ E++ + + L + L
Sbjct: 888 ----ALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLK 943
Query: 634 EKITTLKDTEIPQLE-KRIVDVDTQIKTLNETVEEIT---MSLIEPEQKMTTAKQIHGDM 689
++I LKDT+ PQ++ K +V Q + +T EE+ L E ++K ++
Sbjct: 944 KEIQALKDTK-PQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQ 1002
Query: 690 -PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV---ATAKQVDFK-QKISTLRNRVK 744
+ R +E+ V K V+++ + E L A A+ +D + ++I LR ++
Sbjct: 1003 EEQIARKEEELSRV--KERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELR 1060
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q++ ++L+ L ++ +E Q+ Q + LE+ + + +
Sbjct: 1061 RLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQ 1120
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
L+ ++E + + +E +A +E A K K + +E Q +K
Sbjct: 1121 QDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG 1180
Query: 865 NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKA 924
+ +E+++++ + ++ ++++ + L ++ L+ +K L + K
Sbjct: 1181 DTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREE--NHKL 1238
Query: 925 QTDITNWQKQDDELNEKLN 943
Q + N Q + L ++N
Sbjct: 1239 QLERENLQLETRRLQSEIN 1257
>AF041004-1|AAD17459.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 60.5 bits (140), Expect = 4e-08
Identities = 86/439 (19%), Positives = 200/439 (45%), Gaps = 31/439 (7%)
Query: 661 LNETVEEITMSLIEPEQKMTTAK---QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
+ E +E+ +PE + + +I +++R EI + K+ +A+K+ V
Sbjct: 1228 VKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQ 1287
Query: 718 SEMTLDVATAKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
++ + Q D K+++++LR ++ QKK ++ + E+ + +EEL +
Sbjct: 1288 TKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVK 1347
Query: 776 KKV--QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE------KIEAKTEVV 827
++V Q++V EE + L+++ I L L+ ++E + E +
Sbjct: 1348 ERVVQQEVVRYEE-EPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEEL 1406
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ---HKKKNVPREMEKIQEANDKLMEKQ 884
R R + +++ ++ +AE ++ H +K V ++ + + L +
Sbjct: 1407 ERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQL 1466
Query: 885 KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN-EKLN 943
++ RQ+L +++TL+ ++A E K ++ + + L ++ +K D E ++L
Sbjct: 1467 EEEQHRRQLLEGELETLRRKLAALE--KAEVKEKVVL----SESVQVEKGDTEQEIQRLK 1520
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEK-SLSK-DIEKKFR 1001
+EE K L ++ ++L + +E S+ K L R E K L + +++ + R
Sbjct: 1521 SSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETR 1580
Query: 1002 EKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEI 1061
E+++ +D+R VA D H ++ ++ + +L +++ + D++ E+
Sbjct: 1581 RLQSEINMAATETRDLRNMTVA-DSGTN--HDSRLWSLERELDDL-KRLSKDKDLEIDEL 1636
Query: 1062 -KTEGNLTVESERRKYDYR 1079
K G++ V+ E+R+ R
Sbjct: 1637 QKRLGSVAVKREQRENHLR 1655
Score = 41.5 bits (93), Expect = 0.018
Identities = 96/559 (17%), Positives = 229/559 (40%), Gaps = 32/559 (5%)
Query: 397 QQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHK 456
Q+++ E E Q + +++ Q++ + ++ +L+EK+ EE L + +L L+ +
Sbjct: 1049 QEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQ--EEELSFLQDKLKRLEKER- 1105
Query: 457 TALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE 516
A+ E G + K+ + + K + EV + E+ + +
Sbjct: 1106 -AMAE--GKITVKE-VLKVEK-DAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWA 1160
Query: 517 RRSELTKA--EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD 574
E K ++K+ + +P S+ +L +++ + + + Y+ +L+
Sbjct: 1161 LEEENAKVVVQEKVREI--VRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELE- 1217
Query: 575 NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI-LSMKSLN 633
L RG + E + + +L+++ E++ + + L + L
Sbjct: 1218 ----ALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLK 1273
Query: 634 EKITTLKDTEIPQLE-KRIVDVDTQIKTLNETVEEIT---MSLIEPEQKMTTAKQIHGDM 689
++I LKDT+ PQ++ K +V Q + +T EE+ L E ++K ++
Sbjct: 1274 KEIQALKDTK-PQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQ 1332
Query: 690 -PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV---ATAKQVDFK-QKISTLRNRVK 744
+ R +E+ V K V+++ + E L A A+ +D + ++I LR ++
Sbjct: 1333 EEQIARKEEELSRV--KERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELR 1390
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q++ ++L+ L ++ +E Q+ Q + LE+ + + +
Sbjct: 1391 RLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQ 1450
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
L+ ++E + + +E +A +E A K K + +E Q +K
Sbjct: 1451 QDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG 1510
Query: 865 NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKA 924
+ +E+++++ + ++ ++++ + L ++ L+ +K L + K
Sbjct: 1511 DTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREE--NHKL 1568
Query: 925 QTDITNWQKQDDELNEKLN 943
Q + N Q + L ++N
Sbjct: 1569 QLERQNLQLETRRLQSEIN 1587
>AF013717-1|AAC39668.1| 1756|Homo sapiens periplakin protein.
Length = 1756
Score = 60.5 bits (140), Expect = 4e-08
Identities = 86/439 (19%), Positives = 200/439 (45%), Gaps = 31/439 (7%)
Query: 661 LNETVEEITMSLIEPEQKMTTAK---QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
+ E +E+ +PE + + +I +++R EI + K+ +A+K+ V
Sbjct: 1228 VKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQ 1287
Query: 718 SEMTLDVATAKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
++ + Q D K+++++LR ++ QKK ++ + E+ + +EEL +
Sbjct: 1288 TKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVK 1347
Query: 776 KKV--QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE------KIEAKTEVV 827
++V Q++V EE + L+++ I L L+ ++E + E +
Sbjct: 1348 ERVVQQEVVRYEE-EPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEEL 1406
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ---HKKKNVPREMEKIQEANDKLMEKQ 884
R R + +++ ++ +AE ++ H +K V ++ + + L +
Sbjct: 1407 ERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQL 1466
Query: 885 KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN-EKLN 943
++ RQ+L +++TL+ ++A E K ++ + + L ++ +K D E ++L
Sbjct: 1467 EEEQHRRQLLEGELETLRRKLAALE--KAEVKEKVVL----SESVQVEKGDTEQEIQRLK 1520
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEK-SLSK-DIEKKFR 1001
+EE K L ++ ++L + +E S+ K L R E K L + +++ + R
Sbjct: 1521 SSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETR 1580
Query: 1002 EKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEI 1061
E+++ +D+R VA D H ++ ++ + +L +++ + D++ E+
Sbjct: 1581 RLQSEINMAATETRDLRNMTVA-DSGTN--HDSRLWSLERELDDL-KRLSKDKDLEIDEL 1636
Query: 1062 -KTEGNLTVESERRKYDYR 1079
K G++ V+ E+R+ R
Sbjct: 1637 QKRLGSVAVKREQRENHLR 1655
Score = 41.5 bits (93), Expect = 0.018
Identities = 96/559 (17%), Positives = 229/559 (40%), Gaps = 32/559 (5%)
Query: 397 QQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHK 456
Q+++ E E Q + +++ Q++ + ++ +L+EK+ EE L + +L L+ +
Sbjct: 1049 QEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQ--EEELSFLQDKLKRLEKER- 1105
Query: 457 TALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE 516
A+ E G + K+ + + K + EV + E+ + +
Sbjct: 1106 -AMAE--GKITVKE-VLKVEK-DAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWA 1160
Query: 517 RRSELTKA--EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD 574
E K ++K+ + +P S+ +L +++ + + + Y+ +L+
Sbjct: 1161 LEEENAKVVVQEKVREI--VRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELE- 1217
Query: 575 NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI-LSMKSLN 633
L RG + E + + +L+++ E++ + + L + L
Sbjct: 1218 ----ALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLK 1273
Query: 634 EKITTLKDTEIPQLE-KRIVDVDTQIKTLNETVEEIT---MSLIEPEQKMTTAKQIHGDM 689
++I LKDT+ PQ++ K +V Q + +T EE+ L E ++K ++
Sbjct: 1274 KEIQALKDTK-PQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQ 1332
Query: 690 -PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV---ATAKQVDFK-QKISTLRNRVK 744
+ R +E+ V K V+++ + E L A A+ +D + ++I LR ++
Sbjct: 1333 EEQIARKEEELSRV--KERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELR 1390
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q++ ++L+ L ++ +E Q+ Q + LE+ + + +
Sbjct: 1391 RLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQ 1450
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
L+ ++E + + +E +A +E A K K + +E Q +K
Sbjct: 1451 QDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG 1510
Query: 865 NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKA 924
+ +E+++++ + ++ ++++ + L ++ L+ +K L + K
Sbjct: 1511 DTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREE--NHKL 1568
Query: 925 QTDITNWQKQDDELNEKLN 943
Q + N Q + L ++N
Sbjct: 1569 QLERQNLQLETRRLQSEIN 1587
>AF001691-1|AAC17738.1| 1756|Homo sapiens 195 kDa cornified envelope
precursor protein.
Length = 1756
Score = 60.5 bits (140), Expect = 4e-08
Identities = 86/439 (19%), Positives = 200/439 (45%), Gaps = 31/439 (7%)
Query: 661 LNETVEEITMSLIEPEQKMTTAK---QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD 717
+ E +E+ +PE + + +I +++R EI + K+ +A+K+ V
Sbjct: 1228 VKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLKKEIQALKDTKPQVQ 1287
Query: 718 SEMTLDVATAKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
++ + Q D K+++++LR ++ QKK ++ + E+ + +EEL +
Sbjct: 1288 TKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQEEQIARKEEELSRVK 1347
Query: 776 KKV--QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE------KIEAKTEVV 827
++V Q++V EE + L+++ I L L+ ++E + E +
Sbjct: 1348 ERVVQQEVVRYEE-EPGLRAEASAFAESIDVELRQIDKLRAELRRLQRRRTELERQLEEL 1406
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ---HKKKNVPREMEKIQEANDKLMEKQ 884
R R + +++ ++ +AE ++ H +K V ++ + + L +
Sbjct: 1407 ERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQQDPQQAREHALLRLQL 1466
Query: 885 KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELN-EKLN 943
++ RQ+L +++TL+ ++A E K ++ + + L ++ +K D E ++L
Sbjct: 1467 EEEQHRRQLLEGELETLRRKLAALE--KAEVKEKVVL----SESVQVEKGDTEQEIQRLK 1520
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEK-SLSK-DIEKKFR 1001
+EE K L ++ ++L + +E S+ K L R E K L + +++ + R
Sbjct: 1521 SSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREENHKLQLERQNLQLETR 1580
Query: 1002 EKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEI 1061
E+++ +D+R VA D H ++ ++ + +L +++ + D++ E+
Sbjct: 1581 RLQSEINMAATETRDLRNMTVA-DSGTN--HDSRLWSLERELDDL-KRLSKDKDLEIDEL 1636
Query: 1062 -KTEGNLTVESERRKYDYR 1079
K G++ V+ E+R+ R
Sbjct: 1637 QKRLGSVAVKREQRENHLR 1655
Score = 41.5 bits (93), Expect = 0.018
Identities = 96/559 (17%), Positives = 229/559 (40%), Gaps = 32/559 (5%)
Query: 397 QQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHK 456
Q+++ E E Q + +++ Q++ + ++ +L+EK+ EE L + +L L+ +
Sbjct: 1049 QEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQ--EEELSFLQDKLKRLEKER- 1105
Query: 457 TALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE 516
A+ E G + K+ + + K + EV + E+ + +
Sbjct: 1106 -AMAE--GKITVKE-VLKVEK-DAATEREVSDLTRQYEDEAAKARASQREKTELLRKIWA 1160
Query: 517 RRSELTKA--EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD 574
E K ++K+ + +P S+ +L +++ + + + Y+ +L+
Sbjct: 1161 LEEENAKVVVQEKVREI--VRPDPKAESEVANLRLELVEQERKYRGAEEQLRSYQSELE- 1217
Query: 575 NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI-LSMKSLN 633
L RG + E + + +L+++ E++ + + L + L
Sbjct: 1218 ----ALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLIERCDLEIYQLK 1273
Query: 634 EKITTLKDTEIPQLE-KRIVDVDTQIKTLNETVEEIT---MSLIEPEQKMTTAKQIHGDM 689
++I LKDT+ PQ++ K +V Q + +T EE+ L E ++K ++
Sbjct: 1274 KEIQALKDTK-PQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQKKQVDLERERASQ 1332
Query: 690 -PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV---ATAKQVDFK-QKISTLRNRVK 744
+ R +E+ V K V+++ + E L A A+ +D + ++I LR ++
Sbjct: 1333 EEQIARKEEELSRV--KERVVQQEVVRYEEEPGLRAEASAFAESIDVELRQIDKLRAELR 1390
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
Q++ ++L+ L ++ +E Q+ Q + LE+ + + +
Sbjct: 1391 RLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREKVTHTQKVVLQ 1450
Query: 805 XXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
L+ ++E + + +E +A +E A K K + +E Q +K
Sbjct: 1451 QDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVVLSESVQVEKG 1510
Query: 865 NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKA 924
+ +E+++++ + ++ ++++ + L ++ L+ +K L + K
Sbjct: 1511 DTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDFLREE--NHKL 1568
Query: 925 QTDITNWQKQDDELNEKLN 943
Q + N Q + L ++N
Sbjct: 1569 QLERQNLQLETRRLQSEIN 1587
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 60.5 bits (140), Expect = 4e-08
Identities = 176/909 (19%), Positives = 341/909 (37%), Gaps = 62/909 (6%)
Query: 170 EGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKN 229
E + KER + D + Y ++ LK+ + + +LE+ +A+ +L + K+N
Sbjct: 328 EVSRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN 384
Query: 230 TSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIA-EIENITEVQT 288
+ K+ + + +++ K L +N + + + E+ + E+E I+ +T
Sbjct: 385 LQL---KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS--RT 439
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXX 348
+E +E K++ +V L S ++ ++ K V+E R+
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKT---VEELRTTVDSVEGNASKILKM 496
Query: 349 XXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEKAV 407
N+ K+ A+ E IE ++ K +
Sbjct: 497 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
EQ + +++ + + + +A+ + K++ +EN E + + K + +E
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHES---IKETSSKLSKIEFEKRQI 613
Query: 468 EKDFAVTINKFEC--EVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE 525
+K+ K E E+ NE+ L+ + I E+L + SEL +
Sbjct: 614 KKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI-EALEQENSELEREN 672
Query: 526 DKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSC----CPLC 581
K+ K + T +E L+ E + L + + LK S L
Sbjct: 673 RKLKKTLD------SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLE 726
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTE--DLQRASAKKDEILSMKSLNEKITTL 639
N+ E+E E +LE + D++ +K S K + + + L
Sbjct: 727 NKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESEL 786
Query: 640 KDTEIPQ--LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ 697
+D E+ L+K + ++ K L + +E E Q KQ+ + L R
Sbjct: 787 QDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRL-RQQA 845
Query: 698 EIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD-FKQKISTLRNRVKTTQKKLNAHNKK 756
EIK T + VK G+++ E + +K++ +K+ L+ K ++ +
Sbjct: 846 EIKDTTLEENNVK--IGNLEKE---NKTLSKEIGIYKESCVRLKELEKENKELVKRATID 900
Query: 757 LQTLYEKKTKAKEELLNTQKKVQDIVNL--EESKKQLQSDCXXXXXXXXXXXXAI--TPL 812
++TL + E L TQ+ D+ L E K L + + + L
Sbjct: 901 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKL 960
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK 872
E LK+ +E K E + +E + Y ++ VK ++Q + + +
Sbjct: 961 ESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSP 1020
Query: 873 IQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE------IAKQEVYKRDLDD-NLCLRKAQ 925
D E++ Q T R++L K ++ E A+++ K L Q
Sbjct: 1021 PISGEDNKWERESQ-ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1079
Query: 926 TDITNWQKQD---DELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
I Q+Q E N L N + E +L + T L Q A+ S L+ +
Sbjct: 1080 AQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENE 1139
Query: 983 GFRNELE--KSLSKDIEKKFREKMYELHVTKAIDKD--IREYAV--ALDKCLMEFHREKM 1036
E E KSL + K EK+ LH +A + + I ++ + K L HR+
Sbjct: 1140 SVIKEREDLKSLYDSLIKD-HEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLE 1198
Query: 1037 ENINMIIRE 1045
+ N ++++
Sbjct: 1199 DRYNQLLKQ 1207
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 60.1 bits (139), Expect = 5e-08
Identities = 160/861 (18%), Positives = 340/861 (39%), Gaps = 84/861 (9%)
Query: 188 SDCLDRLKKIRKDYAQNL-KLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S ++L+ R D+ + + L E++ + QKE++ Y +KE E + ++
Sbjct: 553 SSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHA 612
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E + I L E ++Q +E K++ + + +T E AE KT +EK+ L
Sbjct: 613 NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL-GTETAEFAE--LKTQIEKMR-L 668
Query: 307 KSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQS 366
H+++ Q ++ + R+ H + + A +S
Sbjct: 669 DYQHEIENLQNQQDSE---------RAAHAK----EMEALRAKLMKVIKEKENSLEAIRS 715
Query: 367 XXXXXXXXXXXXXXXXXHKQAENELNIEE---CQQEINEDEKAVEQYEQEMDELSQK--- 420
+K E E+ ++E Q + NE K ++ + ++ +K
Sbjct: 716 KLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLD 775
Query: 421 ITKLQKQTAKLK-EKEMIEENLKTKEKQ---LIVLKNKHKTALMELLGNVPEKDFAVT-I 475
+ L+K +++ K E + + + L+ EKQ L + KN + + + ++ +T +
Sbjct: 776 LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNL 835
Query: 476 NKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKAC--- 532
+ EV E ++ S+ E ++L + E++
Sbjct: 836 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 895
Query: 533 -----GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKG----QL-KDNSCCPLCN 582
+ + E+L + L++ + I K G QL K N L
Sbjct: 896 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKE 955
Query: 583 RGFEN-ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLK- 640
R E + + ++ K + Q A+ K +E K L K++ L+
Sbjct: 956 RDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE--EKKELERKLSDLEK 1013
Query: 641 -----DTEIPQLEKRIVDVDTQIKTLNETV-EEITMSLIEPEQKMTTAKQIHGDMPMLDR 694
+ +L+ R ++ KT +E + + + +L++ E K+ A++ + +
Sbjct: 1014 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGL----- 1068
Query: 695 YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+QE++ + K+ E K D+ ++ T K+K TL + T Q N
Sbjct: 1069 -LQELEELRKQAEKAKAAQTAEDAMQIMEQMT------KEKTETLASLEDTKQTNAKLQN 1121
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDIVN--LEESKKQLQSDCXXXXXXXXXXXXAITPL 812
+L TL E K EE LN K++ + N +EE +K++++ A+
Sbjct: 1122 -ELDTLKENNLKNVEE-LNKSKELLTVENQKMEEFRKEIET-LKQAAAQKSQQLSALQEE 1178
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSA---YIAKVEVAFNK-VKSLDAEIQQHKKKNVPR 868
V L E++ + V ++ L E S + +++ +K +K D E + +K++
Sbjct: 1179 NVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEE-KASLQKSISI 1237
Query: 869 EMEKIQEANDKLMEKQKQIMTDR------QVLTKKIDTLKDEIAKQEVYKRDLDDNLCLR 922
+ E + +L + + ++ R + L + TL+ + K E+ ++L+ L L+
Sbjct: 1238 TSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLE--LQLK 1295
Query: 923 KAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
+ + +++ D ++ + +++ S+I+ + Q +SE +L
Sbjct: 1296 ENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSE--AALN 1353
Query: 983 GFRNELEKSLSKDIEKKFREK 1003
G ++L S D EK+ ++K
Sbjct: 1354 GNGDDLNNYDSDDQEKQSKKK 1374
Score = 59.3 bits (137), Expect = 8e-08
Identities = 163/842 (19%), Positives = 335/842 (39%), Gaps = 75/842 (8%)
Query: 81 QVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKD-VSSRCADLD 139
Q KL++ D Q E+T S+K A+++T + + + + ++ K + + S+ +
Sbjct: 556 QEKLEVTRT-DHQREIT-SLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHAN 613
Query: 140 ILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRK 199
+ + + K+ L + + HQ+ E KV + ++++ +++K+R
Sbjct: 614 KENSDVIALWKSKLETAIASHQQAM-----EELKVSFSKGLGTETAEFAELKTQIEKMRL 668
Query: 200 DYAQNLKLLENYATTVKAKQ-KELEDSYKKNTSFNKEEEKI--ANEKSSNEIEYNKFILL 256
DY ++ L+N + +A KE+E K KE+E A ++ E + +
Sbjct: 669 DYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEM 728
Query: 257 E---SQNQEKIDKRNEQIVETAKIAE----IENITEVQTNEEAENATKTILEKVESL-KS 308
E ++ QE K E V AK E I+N T E + L K S KS
Sbjct: 729 EDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKS 788
Query: 309 DHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXX 368
+ K + Q + EK+ + E ++ + +++ +Q
Sbjct: 789 EMKKLRQQLEAAEKQIKHLEIE-KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 847
Query: 369 XXXXXXXXXXXXXXXHKQAENELNIEECQQE-INEDEKAVEQYEQEMDELSQKITKLQKQ 427
+ +E ++++ QE +N+ + EQ+ +L + L
Sbjct: 848 TLEKELQILKEKFA--EASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADM 905
Query: 428 TAKLKEKEMIEENL-KTKEK------QLIVLKNKHKTALMELLGNVPEKDFAVTINKFEC 480
AK +EK+ EE L K KEK +++ + + + L ++ + K+ V + +
Sbjct: 906 EAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKL 965
Query: 481 EVRNE---VXXXXXXXXXXXXXXXXLEAERKHIRE--SLNERRSELTKAEDKIYKACGTQ 535
NE EA +KH E L + S+L K + + C Q
Sbjct: 966 TKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQC--Q 1023
Query: 536 PYDVTLSKYTTTVEKLQDE--QNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXX 593
+ T+ + +E QN+ ++ + +K KG ++NS ++E
Sbjct: 1024 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAK 1083
Query: 594 XXXXXXXXXMNVPGKLEKVT------EDLQRASAK-KDEILSMKSLN----EKITTLKD- 641
+ ++ T ED ++ +AK ++E+ ++K N E++ K+
Sbjct: 1084 AAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKEL 1143
Query: 642 ------------TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
EI L++ Q+ L E ++ L ++T+ +++ +
Sbjct: 1144 LTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER 1203
Query: 690 PMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLRNRVKTTQK 748
+L+ + E+K KF +K+ + S + ++ + +A + ++ LRN V T +
Sbjct: 1204 SVLNNQLLEMKKRESKF--IKDADEEKASLQKSISITSALLTEKDAELEKLRNEV-TVLR 1260
Query: 749 KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXX 807
NA K L ++ + K +L + KV+++ + L+E+K+QL S
Sbjct: 1261 GENASAKSLHSVVQTLESDKVKL---ELKVKNLELQLKENKRQLSSSSGNTDTQADEDER 1317
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDL-IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNV 866
A L I ++ R+N+DL ++ A + + + + D++ Q+ + K
Sbjct: 1318 AQESQIDFLNSVI---VDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKK 1374
Query: 867 PR 868
PR
Sbjct: 1375 PR 1376
Score = 58.8 bits (136), Expect = 1e-07
Identities = 116/608 (19%), Positives = 233/608 (38%), Gaps = 51/608 (8%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
E I+ + E N + +E+ K+T LQ+ L E ++E L EK+L
Sbjct: 801 EKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN---LSEVSQVKETL---EKELQ 854
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+LK K A E + ++ T+NK + + +EA+
Sbjct: 855 ILKEKFAEASEEAVS--VQRSMQETVNKLH-QKEEQFNMLSSDLEKLRENLADMEAK--- 908
Query: 510 IRESLNERRSELTKAEDK-------IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
RE +ER +L KA++K I K G P +T K + + + LQ +
Sbjct: 909 FREK-DEREEQLIKAKEKLENDIAEIMKMSGDNPSQLT--KMNDELRLKERDVEELQLKL 965
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
N+ L+ + + + + E + KL + + ++ + +
Sbjct: 966 TKANENASFLQKS----IEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQ 1021
Query: 623 KDEILSMKSLNEKITTLKDTEIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIE---PEQK 678
E+ + T K EI Q L+K ++D + ++K E + L E +K
Sbjct: 1022 CQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEK 1081
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM-TLDVATAKQVDF----- 732
A+ M ++++ +E E K+ + +E+ TL K V+
Sbjct: 1082 AKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSK 1141
Query: 733 ------KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
QK+ R ++T ++ +++L L E+ K EEL ++ +V LEE
Sbjct: 1142 ELLTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEE 1201
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ L + + +L++ I + ++ +E + +
Sbjct: 1202 ERSVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRG 1261
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
KSL + +Q + V E+ K++ +L E ++Q+ + + DT DE
Sbjct: 1262 ENASAKSLHSVVQTLESDKVKLEL-KVKNLELQLKENKRQLSSS----SGNTDTQADEDE 1316
Query: 907 KQEVYKRDLDDNLC--LRKAQTDITNWQKQDDE--LNEKLNGINKEELNEKESLIIKQTK 962
+ + + D +++ L++ D+ + E LN + +N + +++E K+ +
Sbjct: 1317 RAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPR 1376
Query: 963 LFQQKAEC 970
LF +C
Sbjct: 1377 LFCDICDC 1384
Score = 46.8 bits (106), Expect = 5e-04
Identities = 86/396 (21%), Positives = 175/396 (44%), Gaps = 53/396 (13%)
Query: 637 TTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI 696
T L+ I +LE+ ++ T+ L +E+ ++ + + ++ ++ D+ + +
Sbjct: 470 TKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIM---ELEKDLALR---V 523
Query: 697 QEIKTVTKKFEAVKEQCGDVDSEMTL--DVATAKQ------VDFKQKISTLRN----RVK 744
QE+ + ++ E+ K GDVD ++L ++++ ++ D +++I++L+ R +
Sbjct: 524 QEVAELRRRLESNKP-AGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREE 582
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
T QK++ A + L ++ K +L + K+ D++ L +SK L++
Sbjct: 583 THQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSK--LETAIASHQQAMEE 640
Query: 805 XXXAITP-LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK 863
+ + L E E KT++ + D Y ++E N D+E H K
Sbjct: 641 LKVSFSKGLGTETAEFAELKTQIEKMRLD-------YQHEIE---NLQNQQDSERAAHAK 690
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL-CLR 922
EME ++ KLM+ K+ + + K+D +D+ + +++D L L+
Sbjct: 691 -----EMEALRA---KLMKVIKEKENSLEAIRSKLDKAEDQ------HLVEMEDTLNKLQ 736
Query: 923 KAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
+A+ + K+ + L K N K N L + KL A A SE K +K
Sbjct: 737 EAEIKV----KELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDA-LRKASSEGKSEMK 791
Query: 983 GFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR 1018
R +LE + K I+ EK E +I ++++
Sbjct: 792 KLRQQLE-AAEKQIKHLEIEKNAESSKASSITRELQ 826
Score = 42.7 bits (96), Expect = 0.008
Identities = 81/472 (17%), Positives = 184/472 (38%), Gaps = 34/472 (7%)
Query: 64 ECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVD 123
E V AK N T+V+ ++ ++K L++ K A ++ K++ + L L +
Sbjct: 744 ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRK--ASSEGKSEMKKLRQQLEAAE 801
Query: 124 ESGKTKDV--SSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEI 181
+ K ++ ++ + + E G + N QE+ L E +VKE ++
Sbjct: 802 KQIKHLEIEKNAESSKASSITRELQGRELKLTNL-----QEN----LSEVSQVKETLEKE 852
Query: 182 FDA--DKYSDCLDRLKKIRKDYAQNLKLLEN-------YATTVKAKQKELEDSYKKNTSF 232
+K+++ + +++ + + L ++ ++ ++ L D K
Sbjct: 853 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREK 912
Query: 233 NKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEA 292
++ EE++ K E + + + + N ++ K N+++ + E + + NE A
Sbjct: 913 DEREEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTKANENA 972
Query: 293 ENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXX 352
K+I + ++K++ Q++ EE+K + ++ S +
Sbjct: 973 SFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKE--LERKLSDLEKKMETSHNQCQELKAR 1028
Query: 353 XXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA-VEQYE 411
+ + ++ + EN ++E ++ + EKA Q
Sbjct: 1029 YERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTA 1088
Query: 412 QEMDELSQKITKLQKQT-AKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKD 470
++ ++ +++TK + +T A L++ + L + +L LK + + EL N ++
Sbjct: 1089 EDAMQIMEQMTKEKTETLASLEDTKQTNAKL---QNELDTLKENNLKNVEEL--NKSKEL 1143
Query: 471 FAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V K E E R E+ L+ E + E L R E+T
Sbjct: 1144 LTVENQKME-EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVT 1194
Score = 40.7 bits (91), Expect = 0.031
Identities = 81/417 (19%), Positives = 173/417 (41%), Gaps = 37/417 (8%)
Query: 618 RASAKKDEILSMKSLNEKITTLKDTEIPQLE---KRIVDVDTQIKTLNETVEEITMSLIE 674
R + EI ++ + EK++ ++ +LE K DV K+ ET +E
Sbjct: 580 REETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAME 639
Query: 675 PEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFE-AVKEQCGDVDSEMTLDVATAKQVDFK 733
E K++ +K + + +I+ + ++ ++ DSE A AK+++
Sbjct: 640 -ELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERA---AHAKEMEAL 695
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLN----TQKKVQDIVNLEESKK 789
+ + L +K + L A KL ++ E+ LN + KV+++ L+
Sbjct: 696 R--AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCN 753
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
+ + L+ K E K+E+ ++ R +EA I +E+ N
Sbjct: 754 EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEM-KKLRQQLEAAEKQIKHLEIEKN 812
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQE 909
S K ++ RE++ + L E ++ ++ L K++ LK++ A+
Sbjct: 813 AESS--------KASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEAS 864
Query: 910 VYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
++ + ++++ + N Q + E+ N ++ + +E+L + K F++K E
Sbjct: 865 ------EEAVSVQRSMQETVNKLHQKE---EQFNMLSSDLEKLRENLADMEAK-FREKDE 914
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
L + K+ L+ E+ K +S D + + EL + ++D+ E + L K
Sbjct: 915 REEQLIKAKEKLENDIAEIMK-MSGDNPSQLTKMNDELRLK---ERDVEELQLKLTK 967
Score = 33.5 bits (73), Expect = 4.7
Identities = 52/268 (19%), Positives = 113/268 (42%), Gaps = 17/268 (6%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK-VTALAKKKTKFQTLDSFLSTVDESG 126
H+ + + L + K+ A+++ + + ++ + A+K QT + + +++
Sbjct: 1040 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDAMQIMEQM- 1098
Query: 127 KTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFD-EIFDAD 185
TK+ + A L E+ + A L + + +E++ ++E K KE E +
Sbjct: 1099 -TKEKTETLASL-----EDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKME 1152
Query: 186 KYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
++ ++ LK+ +Q L L+ + + D + +E + N+
Sbjct: 1153 EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLE 1212
Query: 246 NEIEYNKFILLESQNQEKIDKRNE--QIVETAKIAEIENITEVQTNEEAENAT-KTILEK 302
+ +KFI + + + K + T K AE+E + T ENA+ K++
Sbjct: 1213 MKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1272
Query: 303 VESLKSDH-----KVQKSQADEEEKKAQ 325
V++L+SD KV+ + +E K Q
Sbjct: 1273 VQTLESDKVKLELKVKNLELQLKENKRQ 1300
>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
AKAP350 protein.
Length = 3595
Score = 60.1 bits (139), Expect = 5e-08
Identities = 95/393 (24%), Positives = 171/393 (43%), Gaps = 34/393 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
Q EK D+ Q+K L VEE IE EQ+ T D+ ++ +++ +K
Sbjct: 1699 QAEKDRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELM---DLRQQNQALEKQLEKMRK 1755
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
F + EQ +D E DV F+Q+I L ++K + Q + E +T
Sbjct: 1756 F--LDEQA--IDREHERDV-------FQQEIQKLEQQLKVV--------PRFQPISEHQT 1796
Query: 766 KAKEELLN-TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
+ E+L N ++K L SK+QLQ D + LE AL +
Sbjct: 1797 REVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQ 1856
Query: 825 EVV-RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+V R++ +EA +V++ + DA ++ K+ N+ ++E+ +E + E
Sbjct: 1857 KVEDRKHFGAVEAKPELSLEVQLQAER----DAIDRKEKEITNLEEQLEQFREELENKNE 1912
Query: 883 KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL 942
+ +Q+ ++ K+ T E+ ++ +D + L L ++D + Q Q L K
Sbjct: 1913 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ-HVLFGKF 1971
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTG--ALSELKKSLKGFRNELEKSLS-KDIEKK 999
I +E+ E + L + TKL QQ T + E + ++ ++E +S ++ K+
Sbjct: 1972 AQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKR 2031
Query: 1000 FREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
RE+ E + + I+K +E A K M H
Sbjct: 2032 NREEEIE-QLNEVIEKLQQELANIGQKTSMNAH 2063
Score = 54.0 bits (124), Expect = 3e-06
Identities = 135/682 (19%), Positives = 293/682 (42%), Gaps = 61/682 (8%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKN 453
E+ ++ N +++ +++ E ++EL+ KI + +K+T +LK+K + L + ++ IV KN
Sbjct: 1 EQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKN 60
Query: 454 KHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ + L N +K+ + E ++ E + E
Sbjct: 61 QEIKNMKLELTNSKQKE------RQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQ 114
Query: 514 LNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTVEKLQ-----DEQNVLQS-SMFIIN 566
+R+ E +AE D++Y Q + ++ +E+++ + +N L+S S +N
Sbjct: 115 ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVN 174
Query: 567 KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL-QRASAKKDE 625
+ + +L + + L N ++ + + L++ EDL + S +++
Sbjct: 175 EDQIKLMNVAINEL-NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQ 233
Query: 626 I-LSMKSLNEKITTLKD-----TEIPQLEKRIVDVDTQIKTL------NETVEEITMSLI 673
I + +++ E+ + L + + + L+ IV K L T +I + ++
Sbjct: 234 IQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEML 293
Query: 674 EPEQKMTTAKQIHGDMPMLDRY-IQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ--- 729
E E+ + L+R Q + + ++ +KE D++ E +++ K
Sbjct: 294 EKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKE---DLEIEHRINIEKLKDNLG 350
Query: 730 VDFKQKISTLRN----RVKTTQ-KKLNAHNKKLQTLYE-KKTKAKEELLNTQKKVQDIVN 783
+ +KQ+I L+N +++T Q +K N K+ Q + E K K ++ L K + +
Sbjct: 351 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 410
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
+ E +K+++ E+ LK ++ K ++ + DL E + A+
Sbjct: 411 INELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEK-QMKEKENDLQEKFAQLEAE 466
Query: 844 VEVAFNKVKSLDAEIQQHKKKNVPRE---MEKIQ-EANDKLMEKQKQIM-TDRQVLTKKI 898
+ ++ K+L+ ++ H + ++ I+ ++ D + EK+ +I+ + + L ++
Sbjct: 467 NSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQC 526
Query: 899 DTLKDEIAKQEVYKRDLDDN--LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
L +EI KQ + N + ++ Q + K D+L + NK+EL K L
Sbjct: 527 IQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSK---NKQELEYKSKL 583
Query: 957 IIKQTKLFQQKAECTGALSELKKSL----KGFRNELEKSLSKDIEKKFREKMYELHVTKA 1012
+L Q+ T ++K S+ K F E + + +EK E M +L VTK
Sbjct: 584 KALNEELHLQRINPTTV--KMKSSVFDEDKTFVAE-TLEMGEVVEKDTTELMEKLEVTKR 640
Query: 1013 IDKDIREYAVALDKCLMEFHRE 1034
++ + L + L + H E
Sbjct: 641 EKLELSQRLSDLSEQLKQKHGE 662
Score = 46.8 bits (106), Expect = 5e-04
Identities = 112/648 (17%), Positives = 266/648 (41%), Gaps = 71/648 (10%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDEL-SQKITKLQKQTAKLKEKEMIEENLK 442
HK ++ E +I + ++ E ++ +EQ E+DE+ Q+I +++++ + +M E +
Sbjct: 99 HKDSQFETDIVQRMEQ--ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 156
Query: 443 TKEKQLIVLKNKHKTALME---LLGNVPEKDFAVTI---NKFECEVRNEVXXXXXXXXXX 496
K + L++ + E L NV + + + N + +++ E+
Sbjct: 157 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 216
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQN 556
L E RE + R + + E K+ +A + L + + + E
Sbjct: 217 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE 276
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + K K ++ + + +R ES+ + +L K+ EDL
Sbjct: 277 LKHEAEVTNYKIKLEMLEKEKNAVLDR--MAESQEAELERLRTQLLFSHEEELSKLKEDL 334
Query: 617 Q---RASAKK----------DEILSMKS-LNEKITTL---KDTEIPQLEKRIVDV----D 655
+ R + +K +I +++ +++KI T+ KD I + + I+++ D
Sbjct: 335 EIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKD 394
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEA------- 708
Q +N EE+T+ + E ++++ +Q + L++ +QE++ T+ E
Sbjct: 395 LQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 454
Query: 709 -VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK--------TTQKKLNAHNKKLQT 759
++E+ +++E ++ K ++ KI T ++ + ++ K + K+++
Sbjct: 455 DLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEI 514
Query: 760 LYEKKTKAKEELLNTQKKVQD--------IVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
L E+ K++ + ++++ N E + ++LQ + +
Sbjct: 515 LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNK 574
Query: 812 LEVALKEKIEAKTE----------VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
E+ K K++A E V+ + + ++A+ + +V D
Sbjct: 575 QELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAET-LEMGEVVEKDTTELME 633
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
K + RE ++ + L E+ KQ + L +++ +LK E + + R+L+ +
Sbjct: 634 KLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINH 693
Query: 922 RKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
+A+ N Q D +++ L+G+ E + K K F ++++
Sbjct: 694 NRAE----NVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESK 737
Score = 44.8 bits (101), Expect = 0.002
Identities = 42/192 (21%), Positives = 89/192 (46%), Gaps = 15/192 (7%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
+ ++ + +R + + L L I+ L I +LE ++V++ T + E VE
Sbjct: 2263 QTISSEPERTNIQNLNQLREDELGSDISALT-LRISELESQVVEMHTSLILEKEQVEIAE 2321
Query: 670 MSLIEPEQKM---------TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ--CGDVDS 718
+++E E+K+ KQ + + ++ +KT T+ F + +E ++++
Sbjct: 2322 KNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEA 2381
Query: 719 EMTLDVAT-AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
VAT A+ +K+K L+ + + + + K L + + +AKE+L +K
Sbjct: 2382 LRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEK- 2440
Query: 778 VQDIVNLEESKK 789
+D ++ESKK
Sbjct: 2441 -EDETEVQESKK 2451
Score = 44.0 bits (99), Expect = 0.003
Identities = 173/905 (19%), Positives = 357/905 (39%), Gaps = 117/905 (12%)
Query: 172 KKVKERFDEIFDADKYSDCLDR-LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K +KE+ + A+K D L + +K + D + + + + K EL D ++N
Sbjct: 1688 KLMKEKLEVQCQAEKDRDDLQKQVKALEIDVEEQVS---RFIELEQEKNTELMDLRQQNQ 1744
Query: 231 SFNKEEEKIAN--EKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQT 288
+ K+ EK+ ++ + + E+ + + Q++I K +Q+ + + I+E QT
Sbjct: 1745 ALEKQLEKMRKFLDEQAIDREHERDVF-----QQEIQKLEQQL---KVVPRFQPISEHQT 1796
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXX 348
E E + EK + S+ + K Q + ++ +++ +
Sbjct: 1797 RE-VEQLANHLKEKTDKC-SELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADT 1854
Query: 349 XXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAEN-ELNIEECQQEINEDEKAV 407
A K+ N E +E+ ++E+ + V
Sbjct: 1855 FQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEV 1914
Query: 408 EQYEQEMD-ELSQKITKLQK--QTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLG 464
+Q +++ + + T+LQ+ Q KL + +M + L KE + +++H L G
Sbjct: 1915 QQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHV-----LFG 1969
Query: 465 NVPEKDFAVTINKFECEVR--NEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
FA I + E E+ NE +E + + IR+ E + E
Sbjct: 1970 K-----FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDL--ETQIECL 2022
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-QNVLQSSMF---IINKYKGQLKDNSCC 578
++ + C + + + + +EKLQ E N+ Q + +++ LK
Sbjct: 2023 MSDQE----CVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDV 2078
Query: 579 PLCNR-GFENESEXXXXXXXXXXXXMNVPG-KLEKVTEDL-----QRASAKKDEILSMKS 631
+ + E + E + K+ ++T++L +R S +K + + S
Sbjct: 2079 VIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENS 2138
Query: 632 LNEKITTLKDTEIPQLEKRIVDVDTQIKTL-NETV-----EEITMSLIEPEQKMTTAKQI 685
+N I L + P+LE +V + +K+L N+T E S+I E ++ Q+
Sbjct: 2139 VNVAIDHLSKDK-PELE--VVLTEDALKSLENQTYFKSFEENGKGSIINLETRLL---QL 2192
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ D E+ K+ + ++EQ G ++EM Q ++K++
Sbjct: 2193 ESTVSAKDL---ELTQCYKQIKDMQEQ-GQFETEMLQKKIVNLQKIVEEKVAA----ALV 2244
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+Q +L A + + + +T + E + +Q++ L E +L SD
Sbjct: 2245 SQIQLEAVQEYAKFCQDNQTISSEP---ERTNIQNLNQLRED--ELGSDISALTLRISEL 2299
Query: 806 XXAITPLEVAL---KEKIE-AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
+ + +L KE++E A+ V+ + + L+E + K+ + N+ K + E
Sbjct: 2300 ESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLE-----LQKL-LEGNEKKQREKE---- 2349
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQ-IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC 920
KK P+++E ++ + ++ + + L + K E+A + L + L
Sbjct: 2350 -KKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELL 2408
Query: 921 LRKA-----QTDITNWQKQDDELNEKLNGINKEELNEK---------ESLIIKQTKLFQQ 966
+++ Q D++ + E EKL+ + KE+ E E L IK +K
Sbjct: 2409 VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIAS 2468
Query: 967 KAECTGALSELKKSLK------GFRNELEKSLSKD----IEKKFREK---MYELHVTKAI 1013
+ + T +S ++ + G + L+ S + I +F EK M ELH + +
Sbjct: 2469 QTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEIL 2528
Query: 1014 DKDIR 1018
D + R
Sbjct: 2529 DMESR 2533
Score = 40.7 bits (91), Expect = 0.031
Identities = 74/388 (19%), Positives = 157/388 (40%), Gaps = 26/388 (6%)
Query: 614 EDLQRA-SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT-------LNETV 665
EDL+ + ++K L + L E+ L + ++E + + D Q+ L +
Sbjct: 2931 EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLL 2990
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
E + + E + +++H + D Q + + + +KE ++ + + V
Sbjct: 2991 ESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSE-DLLKELQKQLEEKHSRIVE 3049
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLE 785
+ + K K+ +L+ R + +K H K LQT E T+ ++++ Q KV+D+
Sbjct: 3050 LLNETE-KYKLDSLQTR-QQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQL 3107
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVE 845
E K+Q E+ +EK E++ ++ +N + + + +
Sbjct: 3108 EEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESR-RILYQN---LNEPTTWSLTSD 3163
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N V L +I+ K++ ++ ++ + + I Q + K+ L +
Sbjct: 3164 RTRNWV--LQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKA 3221
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE---LNEKESLIIKQTK 962
+++ ++ D++ + D Q Q KL G EE ++ S +
Sbjct: 3222 SERLQFETADDEDFIWVQENIDEIILQLQ------KLTGQQGEEPSLVSPSTSCGSLTER 3275
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEK 990
L +Q AE TG +S+L + RN + K
Sbjct: 3276 LLRQNAELTGHISQLTEEKNDLRNMVMK 3303
Score = 34.3 bits (75), Expect = 2.7
Identities = 30/151 (19%), Positives = 76/151 (50%), Gaps = 7/151 (4%)
Query: 180 EIFDADKYSDCLDRLKKIRKDYAQNLK--LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
E+ + +K + LDR+ + ++ + L+ LL ++ + +++LE ++ N K+
Sbjct: 291 EMLEKEKNA-VLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNL 349
Query: 238 KIANEKSSNEIEYNKFILLESQNQEK---IDKRNEQIVETAKIAEIENITEVQTNEEAEN 294
I ++ + ++ +E+ EK I K+N+ I+E +K+ +++ +EE
Sbjct: 350 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 409
Query: 295 ATKTILEKVESLKSDHKVQKSQADEEEKKAQ 325
+ +++E L+ + K +K ++E ++ Q
Sbjct: 410 QINELQKEIEILRQEEK-EKGTLEQEVQELQ 439
>BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/CAST
family member 2 protein.
Length = 957
Score = 59.7 bits (138), Expect = 6e-08
Identities = 72/363 (19%), Positives = 163/363 (44%), Gaps = 26/363 (7%)
Query: 610 EKVTEDLQRASAKKD-EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+K T + + S KK E+L K L K +L+D + +R+ + ++Q+ L +++
Sbjct: 294 QKQTLNARDESIKKLLEMLQSKGLPSK--SLEDDN--ERTRRMAEAESQVSHLEVILDQK 349
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
I +++ Q+ + P + +Q I+ K +++ D++ E+ + A
Sbjct: 350 EKENIHLREELHRRSQLQPE-PAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANG 408
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
++ + + ++ +++ + K+ L ++ +K + ELL Q K++ + N
Sbjct: 409 V-LNTEDREEEIK-QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSD 466
Query: 788 KKQ----LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
KQ L+ + L + L+EK + ++ +DL E +
Sbjct: 467 CKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE 526
Query: 844 VEVAFN--KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ + +VK + Q K +N+ ++ + L ++ K + TD + TL
Sbjct: 527 IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATL 586
Query: 902 KDEIAKQEVY------KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
++ ++++E +R+ DD R+ +I +++K++ +L EK+N + + EL EKES
Sbjct: 587 EEALSEKERIIERLKEQRERDD----RERLEEIESFRKENKDLKEKVNAL-QAELTEKES 641
Query: 956 LII 958
+I
Sbjct: 642 SLI 644
Score = 58.8 bits (136), Expect = 1e-07
Identities = 148/726 (20%), Positives = 275/726 (37%), Gaps = 83/726 (11%)
Query: 214 TVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVE 273
T++A Q EL N +E E + E+ F L++++ D++ +++
Sbjct: 224 TIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEH----DRQAKELFL 279
Query: 274 TAKIAEIENITEVQTNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECR 332
K E E ++T ++ NA ++K+ E L+S KS D+ E+ + E +
Sbjct: 280 LRKTLE-EMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQ 338
Query: 333 SGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN 392
H + + K A E N
Sbjct: 339 VSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDT-----KIASLERN 393
Query: 393 IEECQQEINE-DEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEKQLIV 450
I + + EI V E +E+ Q I + + +K K + +++ L KE +L+
Sbjct: 394 IRDLEDEIQMLKANGVLNTEDREEEIKQ-IEVYKSHSKFMKTKIDQLKQELSKKESELLA 452
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
L+ K +E L N +C+ EV E + +
Sbjct: 453 LQTK-----LETLSN----------QNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRL 497
Query: 511 RESLNERRSEL---TKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINK 567
R L E+ S L TK + + GT ++ K +E + + NVLQ I
Sbjct: 498 R--LEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMK--DMLEVKERKINVLQKK---IEN 550
Query: 568 YKGQL--KDNSCCPLCNR--GFENESEXXXXXXXXXXXXMNVPGKL-EKVTEDLQRASAK 622
+ QL KD L +R + +S ++ ++ E++ E +R +
Sbjct: 551 LQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRE 610
Query: 623 K-DEILSM----KSLNEKITTLKDTEIPQLEKRIVDV--------------DTQIKTLNE 663
+ +EI S K L EK+ L+ E+ + E ++D+ D+++K+L
Sbjct: 611 RLEEIESFRKENKDLKEKVNALQ-AELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEI 669
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
+E+ + E ++ A I D M + +IK + K+ +++CG +E+
Sbjct: 670 AIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRL 729
Query: 724 VATAKQVDFKQ--KISTLRNRVKTTQKKLNAHNKKLQTL-----YEKKTKAK--EELLNT 774
+ K+V+ ++ K + T + + NKK+ L EKK A+ EE+
Sbjct: 730 LEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRR 789
Query: 775 QKKVQD---IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
+ + D + +EE L+ A T +A KE A + RR +
Sbjct: 790 EDSMADNSQHLQIEELMNALEK--TRQELDATKARLASTQQSLAEKEAHLANLRIERRKQ 847
Query: 832 --DLIE-AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+++E A +A + + L E+ KKK E+ ++ D+L+ + KQ
Sbjct: 848 LEEILEMKQEALLAAISEKDANIALL--ELSASKKKKTQEEVMALKREKDRLVHQLKQQT 905
Query: 889 TDRQVL 894
+R L
Sbjct: 906 QNRMKL 911
Score = 57.6 bits (133), Expect = 3e-07
Identities = 105/522 (20%), Positives = 211/522 (40%), Gaps = 42/522 (8%)
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQNVLQSS 561
E E H+RE L+ RRS+L K KA T + D ++ + L+DE +L+++
Sbjct: 350 EKENIHLREELH-RRSQLQPEPAKT-KALQTVIEMKDTKIASLERNIRDLEDEIQMLKAN 407
Query: 562 MFIINKYKGQ-LKDNSCCPLCNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
+ + + + +K ++ + + + + + KLE ++
Sbjct: 408 GVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDC 467
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ + + E+ + TE+ L R+ + ++ + + ++++T E+K
Sbjct: 468 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT------EEKG 521
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT--LDVATAKQVDFKQK-- 735
T A +I ML+ ++I + KK E ++EQ D D ++T D + Q D
Sbjct: 522 TLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT 581
Query: 736 -ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL--------EE 786
++TL + ++ + ++ + ++ + E K +++ VN E
Sbjct: 582 ALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKES 641
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE--AKTEVVRRNRDLIEAGSAYIAKV 844
S L+ + LE+A+++K E +K E + IE S
Sbjct: 642 SLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRM--NP 699
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD- 903
E A +++K LD E ++ E K Q D+L+E K++ ++ KKI L+
Sbjct: 700 EFA-DQIKQLDKEASYYRD-----ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESL 753
Query: 904 ---EIAKQEVYKRDLDDNLCLRKAQTD--ITNWQKQDDELNEKLNGINKEEL-NEKESLI 957
+ Q +L N L K + + ++++D + + + EEL N E
Sbjct: 754 TLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTR 813
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ + A +L+E + L R E K L + +E K
Sbjct: 814 QELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMK 855
Score = 47.2 bits (107), Expect = 4e-04
Identities = 81/386 (20%), Positives = 165/386 (42%), Gaps = 33/386 (8%)
Query: 647 LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKF 706
LE+ + ++TQ +TLN E I L + K +K + D R + E ++
Sbjct: 284 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRR-MAEAESQVSHL 342
Query: 707 EAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTK 766
E + +D + ++ +++ + ++ + K Q + + K+ +L
Sbjct: 343 EVI------LDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRD 396
Query: 767 AKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV 826
++E+ K ++N E+ +++++ I L+ L +K +
Sbjct: 397 LEDEI--QMLKANGVLNTEDREEEIKQ-IEVYKSHSKFMKTKIDQLKQELSKKESELLAL 453
Query: 827 VRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK--KKNVPREMEKIQEANDKLMEKQ 884
+ L S +EV +SL A+ Q+ + V +++E L +K
Sbjct: 454 QTKLETLSNQNSDCKQHIEVL---KESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKT 510
Query: 885 KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNG 944
KQ+ Q LT++ TL EI RD+ D L +++ + ++ QK+ + L E+L
Sbjct: 511 KQL----QDLTEEKGTLAGEI-------RDMKDMLEVKERKINVL--QKKIENLQEQLRD 557
Query: 945 INKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
+K+ N K+ + QT + AL+ L+++L +E+ L + E+ RE++
Sbjct: 558 KDKQLTNLKDRVKSLQT----DSSNTDTALATLEEALSEKERIIER-LKEQRERDDRERL 612
Query: 1005 YELHVTKAIDKDIREYAVALDKCLME 1030
E+ + +KD++E AL L E
Sbjct: 613 EEIESFRKENKDLKEKVNALQAELTE 638
Score = 39.5 bits (88), Expect = 0.071
Identities = 67/284 (23%), Positives = 120/284 (42%), Gaps = 27/284 (9%)
Query: 748 KKLNAHNKKLQTLYEKKTKAKEELLNTQ-KKVQDIVNLEESK----KQLQSDCXXXXXXX 802
K+L K L+ + E + + +++ LN + + ++ ++ + +SK K L+ D
Sbjct: 275 KELFLLRKTLEEM-ELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDD-NERTRRM 332
Query: 803 XXXXXAITPLEVAL----KEKIEAKTEVVRRNRDLIEAGS--AYIAKVEVAFNKVKSLDA 856
++ LEV L KE I + E+ RR++ E A +E+ K+ SL+
Sbjct: 333 AEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLER 392
Query: 857 EIQQHKKKNVPREMEKIQEANDKLME-KQKQIMTDRQVLTK-KIDTLKDEIAKQEVYKRD 914
I+ + + + + D+ E KQ ++ K KID LK E++K+E
Sbjct: 393 NIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLA 452
Query: 915 LDDNL-CLRKAQTDITNW---QKQDDELNEKLNGINKEE-------LNEKESLIIKQTKL 963
L L L +D K+ E+ I + E L EKES + K+TK
Sbjct: 453 LQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Query: 964 FQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYEL 1007
Q E G L+ + +K E+ ++ ++KK +L
Sbjct: 513 LQDLTEEKGTLAGEIRDMKDMLEVKERKINV-LQKKIENLQEQL 555
>BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein.
Length = 957
Score = 59.7 bits (138), Expect = 6e-08
Identities = 72/363 (19%), Positives = 163/363 (44%), Gaps = 26/363 (7%)
Query: 610 EKVTEDLQRASAKKD-EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+K T + + S KK E+L K L K +L+D + +R+ + ++Q+ L +++
Sbjct: 294 QKQTLNARDESIKKLLEMLQSKGLPSK--SLEDDN--ERTRRMAEAESQVSHLEVILDQK 349
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
I +++ Q+ + P + +Q I+ K +++ D++ E+ + A
Sbjct: 350 EKENIHLREELHRRSQLQPE-PAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANG 408
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
++ + + ++ +++ + K+ L ++ +K + ELL Q K++ + N
Sbjct: 409 V-LNTEDREEEIK-QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSD 466
Query: 788 KKQ----LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
KQ L+ + L + L+EK + ++ +DL E +
Sbjct: 467 CKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE 526
Query: 844 VEVAFN--KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ + +VK + Q K +N+ ++ + L ++ K + TD + TL
Sbjct: 527 IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATL 586
Query: 902 KDEIAKQEVY------KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
++ ++++E +R+ DD R+ +I +++K++ +L EK+N + + EL EKES
Sbjct: 587 EEALSEKERIIERLKEQRERDD----RERLEEIESFRKENKDLKEKVNAL-QAELTEKES 641
Query: 956 LII 958
+I
Sbjct: 642 SLI 644
Score = 58.8 bits (136), Expect = 1e-07
Identities = 148/726 (20%), Positives = 275/726 (37%), Gaps = 83/726 (11%)
Query: 214 TVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVE 273
T++A Q EL N +E E + E+ F L++++ D++ +++
Sbjct: 224 TIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEH----DRQAKELFL 279
Query: 274 TAKIAEIENITEVQTNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECR 332
K E E ++T ++ NA ++K+ E L+S KS D+ E+ + E +
Sbjct: 280 LRKTLE-EMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQ 338
Query: 333 SGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN 392
H + + K A E N
Sbjct: 339 VSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDT-----KIASLERN 393
Query: 393 IEECQQEINE-DEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEKQLIV 450
I + + EI V E +E+ Q I + + +K K + +++ L KE +L+
Sbjct: 394 IRDLEDEIQMLKANGVLNTEDREEEIKQ-IEVYKSHSKFMKTKIDQLKQELSKKESELLA 452
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
L+ K +E L N +C+ EV E + +
Sbjct: 453 LQTK-----LETLSN----------QNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRL 497
Query: 511 RESLNERRSEL---TKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINK 567
R L E+ S L TK + + GT ++ K +E + + NVLQ I
Sbjct: 498 R--LEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMK--DMLEVKERKINVLQKK---IEN 550
Query: 568 YKGQL--KDNSCCPLCNR--GFENESEXXXXXXXXXXXXMNVPGKL-EKVTEDLQRASAK 622
+ QL KD L +R + +S ++ ++ E++ E +R +
Sbjct: 551 LQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRE 610
Query: 623 K-DEILSM----KSLNEKITTLKDTEIPQLEKRIVDV--------------DTQIKTLNE 663
+ +EI S K L EK+ L+ E+ + E ++D+ D+++K+L
Sbjct: 611 RLEEIESFRKENKDLKEKVNALQ-AELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEI 669
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
+E+ + E ++ A I D M + +IK + K+ +++CG +E+
Sbjct: 670 AIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRL 729
Query: 724 VATAKQVDFKQ--KISTLRNRVKTTQKKLNAHNKKLQTL-----YEKKTKAK--EELLNT 774
+ K+V+ ++ K + T + + NKK+ L EKK A+ EE+
Sbjct: 730 LEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRR 789
Query: 775 QKKVQD---IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
+ + D + +EE L+ A T +A KE A + RR +
Sbjct: 790 EDSMADNSQHLQIEELMNALEK--TRQELDATKARLASTQQSLAEKEAHLANLRIERRKQ 847
Query: 832 --DLIE-AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+++E A +A + + L E+ KKK E+ ++ D+L+ + KQ
Sbjct: 848 LEEILEMKQEALLAAISEKDANIALL--ELSASKKKKTQEEVMALKREKDRLVHQLKQQT 905
Query: 889 TDRQVL 894
+R L
Sbjct: 906 QNRMKL 911
Score = 57.6 bits (133), Expect = 3e-07
Identities = 105/522 (20%), Positives = 211/522 (40%), Gaps = 42/522 (8%)
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQNVLQSS 561
E E H+RE L+ RRS+L K KA T + D ++ + L+DE +L+++
Sbjct: 350 EKENIHLREELH-RRSQLQPEPAKT-KALQTVIEMKDTKIASLERNIRDLEDEIQMLKAN 407
Query: 562 MFIINKYKGQ-LKDNSCCPLCNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
+ + + + +K ++ + + + + + KLE ++
Sbjct: 408 GVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDC 467
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ + + E+ + TE+ L R+ + ++ + + ++++T E+K
Sbjct: 468 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT------EEKG 521
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT--LDVATAKQVDFKQK-- 735
T A +I ML+ ++I + KK E ++EQ D D ++T D + Q D
Sbjct: 522 TLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT 581
Query: 736 -ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL--------EE 786
++TL + ++ + ++ + ++ + E K +++ VN E
Sbjct: 582 ALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKES 641
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE--AKTEVVRRNRDLIEAGSAYIAKV 844
S L+ + LE+A+++K E +K E + IE S
Sbjct: 642 SLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRM--NP 699
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD- 903
E A +++K LD E ++ E K Q D+L+E K++ ++ KKI L+
Sbjct: 700 EFA-DQIKQLDKEASYYRD-----ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESL 753
Query: 904 ---EIAKQEVYKRDLDDNLCLRKAQTD--ITNWQKQDDELNEKLNGINKEEL-NEKESLI 957
+ Q +L N L K + + ++++D + + + EEL N E
Sbjct: 754 TLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTR 813
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ + A +L+E + L R E K L + +E K
Sbjct: 814 QELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMK 855
Score = 47.2 bits (107), Expect = 4e-04
Identities = 81/386 (20%), Positives = 165/386 (42%), Gaps = 33/386 (8%)
Query: 647 LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKF 706
LE+ + ++TQ +TLN E I L + K +K + D R + E ++
Sbjct: 284 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRR-MAEAESQVSHL 342
Query: 707 EAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTK 766
E + +D + ++ +++ + ++ + K Q + + K+ +L
Sbjct: 343 EVI------LDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRD 396
Query: 767 AKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV 826
++E+ K ++N E+ +++++ I L+ L +K +
Sbjct: 397 LEDEI--QMLKANGVLNTEDREEEIKQ-IEVYKSHSKFMKTKIDQLKQELSKKESELLAL 453
Query: 827 VRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK--KKNVPREMEKIQEANDKLMEKQ 884
+ L S +EV +SL A+ Q+ + V +++E L +K
Sbjct: 454 QTKLETLSNQNSDCKQHIEVL---KESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKT 510
Query: 885 KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNG 944
KQ+ Q LT++ TL EI RD+ D L +++ + ++ QK+ + L E+L
Sbjct: 511 KQL----QDLTEEKGTLAGEI-------RDMKDMLEVKERKINVL--QKKIENLQEQLRD 557
Query: 945 INKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
+K+ N K+ + QT + AL+ L+++L +E+ L + E+ RE++
Sbjct: 558 KDKQLTNLKDRVKSLQT----DSSNTDTALATLEEALSEKERIIER-LKEQRERDDRERL 612
Query: 1005 YELHVTKAIDKDIREYAVALDKCLME 1030
E+ + +KD++E AL L E
Sbjct: 613 EEIESFRKENKDLKEKVNALQAELTE 638
Score = 39.5 bits (88), Expect = 0.071
Identities = 67/284 (23%), Positives = 120/284 (42%), Gaps = 27/284 (9%)
Query: 748 KKLNAHNKKLQTLYEKKTKAKEELLNTQ-KKVQDIVNLEESK----KQLQSDCXXXXXXX 802
K+L K L+ + E + + +++ LN + + ++ ++ + +SK K L+ D
Sbjct: 275 KELFLLRKTLEEM-ELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDD-NERTRRM 332
Query: 803 XXXXXAITPLEVAL----KEKIEAKTEVVRRNRDLIEAGS--AYIAKVEVAFNKVKSLDA 856
++ LEV L KE I + E+ RR++ E A +E+ K+ SL+
Sbjct: 333 AEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLER 392
Query: 857 EIQQHKKKNVPREMEKIQEANDKLME-KQKQIMTDRQVLTK-KIDTLKDEIAKQEVYKRD 914
I+ + + + + D+ E KQ ++ K KID LK E++K+E
Sbjct: 393 NIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLA 452
Query: 915 LDDNL-CLRKAQTDITNW---QKQDDELNEKLNGINKEE-------LNEKESLIIKQTKL 963
L L L +D K+ E+ I + E L EKES + K+TK
Sbjct: 453 LQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 512
Query: 964 FQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYEL 1007
Q E G L+ + +K E+ ++ ++KK +L
Sbjct: 513 LQDLTEEKGTLAGEIRDMKDMLEVKERKINV-LQKKIENLQEQL 555
>AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A
protein.
Length = 1016
Score = 59.7 bits (138), Expect = 6e-08
Identities = 95/393 (24%), Positives = 171/393 (43%), Gaps = 34/393 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
Q EK D+ Q+K L VEE IE EQ+ T D+ ++ +++ +K
Sbjct: 368 QAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELM---DLRQQNQALEKQLEKMRK 424
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
F + EQ +D E DV F+Q+I L ++K + Q + E +T
Sbjct: 425 F--LDEQA--IDREHERDV-------FQQEIQKLEQQLKVV--------PRFQPISEHQT 465
Query: 766 KAKEELLN-TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
+ E+L N ++K L SK+QLQ D + LE AL +
Sbjct: 466 REVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQ 525
Query: 825 EVV-RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+V R++ +EA +V++ + DA ++ K+ N+ ++E+ +E + E
Sbjct: 526 KVEDRKHFGAVEAKPELSLEVQLQAER----DAIDRKEKEITNLEEQLEQFREELENKNE 581
Query: 883 KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL 942
+ +Q+ ++ K+ T E+ ++ +D + L L ++D + Q Q L K
Sbjct: 582 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ-HVLFGKF 640
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTG--ALSELKKSLKGFRNELEKSLS-KDIEKK 999
I +E+ E + L + TKL QQ T + E + ++ ++E +S ++ K+
Sbjct: 641 AQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKR 700
Query: 1000 FREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
RE+ E + + I+K +E A K M H
Sbjct: 701 NREEEIE-QLNEVIEKLQQELANIGQKTSMNAH 732
Score = 41.5 bits (93), Expect = 0.018
Identities = 50/279 (17%), Positives = 116/279 (41%), Gaps = 15/279 (5%)
Query: 175 KERFDEIFDADKYSDCLDR-LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFN 233
+E+ E+ D + + L++ L+K+RK + E+ + + ++LE K F
Sbjct: 399 QEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQ 458
Query: 234 -------KEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETA-KIAEIEN--I 283
+E E++AN + ++ +L + Q Q I +RNE+I + ++ E+E +
Sbjct: 459 PISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALL 518
Query: 284 TEVQTNEEAENATK--TILEKVE-SLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXX 340
T ++ E+ + K E SL+ + ++ D +EK+ ++ +
Sbjct: 519 VSADTFQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELEN 578
Query: 341 XXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEI 400
T + K+++ ++ ++
Sbjct: 579 KNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESD-AMSTQDQHVLF 637
Query: 401 NEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEE 439
+ + +++ E E+D+L++++TKLQ+Q + ++IEE
Sbjct: 638 GKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEE 676
Score = 35.5 bits (78), Expect = 1.2
Identities = 22/116 (18%), Positives = 57/116 (49%), Gaps = 4/116 (3%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVET 274
++ + K +D +K KE + ++ + + + KF + + + +ID+ NEQ+ +
Sbjct: 604 LEQENKLFKDDMEKLGLAIKESDAMSTQ--DQHVLFGKFAQIIQEKEVEIDQLNEQVTKL 661
Query: 275 AKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+ +++ T+ + EE + + ++E L SD + K +EE ++ +++
Sbjct: 662 QQ--QLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEK 715
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 59.7 bits (138), Expect = 6e-08
Identities = 95/393 (24%), Positives = 171/393 (43%), Gaps = 34/393 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
Q EK D+ Q+K L VEE IE EQ+ T D+ ++ +++ +K
Sbjct: 2012 QAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELM---DLRQQNQALEKQLEKMRK 2068
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
F + EQ +D E DV F+Q+I L ++K + Q + E +T
Sbjct: 2069 F--LDEQA--IDREHERDV-------FQQEIQKLEQQLKVV--------PRFQPISEHQT 2109
Query: 766 KAKEELLN-TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
+ E+L N ++K L SK+QLQ D + LE AL +
Sbjct: 2110 REVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQ 2169
Query: 825 EVV-RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+V R++ +EA +V++ + DA ++ K+ N+ ++E+ +E + E
Sbjct: 2170 KVEDRKHFGAVEAKPELSLEVQLQAER----DAIDRKEKEITNLEEQLEQFREELENKNE 2225
Query: 883 KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL 942
+ +Q+ ++ K+ T E+ ++ +D + L L ++D + Q Q L K
Sbjct: 2226 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ-HVLFGKF 2284
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTG--ALSELKKSLKGFRNELEKSLS-KDIEKK 999
I +E+ E + L + TKL QQ T + E + ++ ++E +S ++ K+
Sbjct: 2285 AQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKR 2344
Query: 1000 FREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
RE+ E + + I+K +E A K M H
Sbjct: 2345 NREEEIE-QLNEVIEKLQQELANIGQKTSMNAH 2376
Score = 52.0 bits (119), Expect = 1e-05
Identities = 131/660 (19%), Positives = 285/660 (43%), Gaps = 61/660 (9%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+E+ ++ N +++ +++ E ++EL+ KI + +K+T +LK+K + L + ++ IV K
Sbjct: 310 MEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK 369
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
N+ + L N +K+ + E ++ E + E
Sbjct: 370 NQEIKNMKLELTNSKQKE------RQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
Query: 513 SLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTVEKLQ-----DEQNVLQS-SMFII 565
+R+ E +AE D++Y Q + ++ +E+++ + +N L+S S +
Sbjct: 424 QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITV 483
Query: 566 NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL-QRASAKKD 624
N+ + +L + + L N ++ + + L++ EDL + S ++
Sbjct: 484 NEDQIKLMNVAINEL-NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 542
Query: 625 EI-LSMKSLNEKITTLKD-----TEIPQLEKRIVDVDTQIKTL------NETVEEITMSL 672
+I + +++ E+ + L + + + L+ IV K L T +I + +
Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 602
Query: 673 IEPEQKMTTAKQIHGDMPMLDRY-IQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ-- 729
+E E+ + L+R Q + + ++ +KE D++ E +++ K
Sbjct: 603 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKE---DLEIEHRINIEKLKDNL 659
Query: 730 -VDFKQKISTLRN----RVKTTQ-KKLNAHNKKLQTLYE-KKTKAKEELLNTQKKVQDIV 782
+ +KQ+I L+N +++T Q +K N K+ Q + E K K ++ L K + +
Sbjct: 660 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 719
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
+ E +K+++ E+ LK ++ K ++ + DL E + A
Sbjct: 720 QINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEK-QMKEKENDLQEKFAQLEA 775
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPRE---MEKIQ-EANDKLMEKQKQIM-TDRQVLTKK 897
+ + ++ K+L+ ++ H + ++ I+ ++ D + EK+ +I+ + + L ++
Sbjct: 776 ENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQ 835
Query: 898 IDTLKDEIAKQEVYKRDLDDN--LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L +EI KQ + N + ++ Q + K D+L + NK+EL K
Sbjct: 836 CIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSK---NKQELEYKSK 892
Query: 956 LIIKQTKLFQQKAECTGALSELKKSL----KGFRNELEKSLSKDIEKKFREKMYELHVTK 1011
L +L Q+ T ++K S+ K F E + + +EK E M +L VTK
Sbjct: 893 LKALNEELHLQRINPTTV--KMKSSVFDEDKTFVAE-TLEMGEVVEKDTTELMEKLEVTK 949
Score = 50.4 bits (115), Expect = 4e-05
Identities = 84/434 (19%), Positives = 190/434 (43%), Gaps = 34/434 (7%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE--KRIVDVDTQIKTLNETVEE 667
+K+ +LQ +K++ +K++ ++T K E E K+++ +++ N +
Sbjct: 356 DKLLGELQEQIVQKNQ--EIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQ 413
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+++ ++ T K + + Y Q+I V K E +++ ++ T
Sbjct: 414 FETDIVQRMEQETQRKLEQLRAELDEMYGQQI--VQMKQELIRQHMAQMEEMKTRHKGEM 471
Query: 728 KQ-VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-------LNTQKKVQ 779
+ + I+ +++K +N N KLQ +K K KEEL Q++++
Sbjct: 472 ENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLE 531
Query: 780 DIV-NLEESKKQLQ------SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
D+V L S++Q+Q ++ + L+ + E++ E+ ++
Sbjct: 532 DLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEA 591
Query: 833 LIEAGSAYIAKVEVAFNKV-----KSLDAEIQQHKKKNVPREMEKIQEANDKL-MEKQKQ 886
+ + +E N V +S +AE+++ + + + E++ + + L +E +
Sbjct: 592 EVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRIN 651
Query: 887 IMTDRQVL----TKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL 942
I + L ++ID L++E++++ + DNL ++ Q I K D L + L
Sbjct: 652 IEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQL-ILEISKLKD-LQQSL 709
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
EE+ + + + K+ ++ +Q+ + G L + + L+ + EL + K+ E +E
Sbjct: 710 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQ-LKTELLEKQMKEKENDLQE 768
Query: 1003 KMYELHVTKAIDKD 1016
K +L +I KD
Sbjct: 769 KFAQLEAENSILKD 782
Score = 44.8 bits (101), Expect = 0.002
Identities = 173/905 (19%), Positives = 357/905 (39%), Gaps = 117/905 (12%)
Query: 172 KKVKERFDEIFDADKYSDCLDR-LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K +KE+ + A+K D L + +K + D + + + + K EL D ++N
Sbjct: 2001 KLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVS---RFIELEQEKNTELMDLRQQNQ 2057
Query: 231 SFNKEEEKIAN--EKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQT 288
+ K+ EK+ ++ + + E+ + + Q++I K +Q+ + + I+E QT
Sbjct: 2058 ALEKQLEKMRKFLDEQAIDREHERDVF-----QQEIQKLEQQL---KVVPRFQPISEHQT 2109
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXX 348
E E + EK + S+ + K Q + ++ +++ +
Sbjct: 2110 RE-VEQLANHLKEKTDKC-SELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADT 2167
Query: 349 XXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAEN-ELNIEECQQEINEDEKAV 407
A K+ N E +E+ ++E+ + V
Sbjct: 2168 FQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEV 2227
Query: 408 EQYEQEMD-ELSQKITKLQK--QTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLG 464
+Q +++ + + T+LQ+ Q KL + +M + L KE + +++H L G
Sbjct: 2228 QQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHV-----LFG 2282
Query: 465 NVPEKDFAVTINKFECEVR--NEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
FA I + E E+ NE +E + + IR+ E + E
Sbjct: 2283 K-----FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDL--ETQIECL 2335
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-QNVLQSSMF---IINKYKGQLKDNSCC 578
++ + C + + + + +EKLQ E N+ Q + +++ LK
Sbjct: 2336 MSDQE----CVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDV 2391
Query: 579 PLCNR-GFENESEXXXXXXXXXXXXMNVPG-KLEKVTEDL-----QRASAKKDEILSMKS 631
+ + E + E + K+ ++T++L +R S +K + + S
Sbjct: 2392 VIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENS 2451
Query: 632 LNEKITTLKDTEIPQLEKRIVDVDTQIKTL-NETV-----EEITMSLIEPEQKMTTAKQI 685
+N I L + P+LE +V + +K+L N+T E S+I E ++ Q+
Sbjct: 2452 VNVAIDHLSKDK-PELE--VVLTEDALKSLENQTYFKSFEENGKGSIINLETRLL---QL 2505
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ D E+ K+ + ++EQ G ++EM Q ++K++
Sbjct: 2506 ESTVSAKDL---ELTQCYKQIKDMQEQ-GQFETEMLQKKIVNLQKIVEEKVAA----ALV 2557
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+Q +L A + + + +T + E + +Q++ L E +L SD
Sbjct: 2558 SQIQLEAVQEYAKFCQDNQTISSEP---ERTNIQNLNQLRED--ELGSDISALTLRISEL 2612
Query: 806 XXAITPLEVAL---KEKIE-AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
+ + +L KE++E A+ V+ + + L+E + K+ + N+ K + E
Sbjct: 2613 ESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLE-----LQKL-LEGNEKKQREKE---- 2662
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQ-IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC 920
KK P+++E ++ + ++ + + L + K E+A + L + L
Sbjct: 2663 -KKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELL 2721
Query: 921 LRKA-----QTDITNWQKQDDELNEKLNGINKEELNEK---------ESLIIKQTKLFQQ 966
+++ Q D++ + E EKL+ + KE+ E E L IK +K
Sbjct: 2722 VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIAS 2781
Query: 967 KAECTGALSELKKSLK------GFRNELEKSLSKD----IEKKFREK---MYELHVTKAI 1013
+ + T +S ++ + G + L+ S + I +F EK M ELH + +
Sbjct: 2782 QTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEIL 2841
Query: 1014 DKDIR 1018
D + R
Sbjct: 2842 DMESR 2846
Score = 43.6 bits (98), Expect = 0.004
Identities = 82/436 (18%), Positives = 187/436 (42%), Gaps = 39/436 (8%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDEL-SQKITKLQKQTAKLKEKEMIEENLK 442
HK ++ E +I + ++ E ++ +EQ E+DE+ Q+I +++++ + +M E +
Sbjct: 409 HKDSQFETDIVQRMEQ--ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 466
Query: 443 TKEKQLIVLKNKHKTALME---LLGNVPEKDFAVTI---NKFECEVRNEVXXXXXXXXXX 496
K + L++ + E L NV + + + N + +++ E+
Sbjct: 467 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 526
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQN 556
L E RE + R + + E K+ +A + L + + + E
Sbjct: 527 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE 586
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + K K ++ + + +R ES+ + +L K+ EDL
Sbjct: 587 LKHEAEVTNYKIKLEMLEKEKNAVLDR--MAESQEAELERLRTQLLFSHEEELSKLKEDL 644
Query: 617 Q---RASAKK----------DEILSMKS-LNEKITTL---KDTEIPQLEKRIVDV----D 655
+ R + +K +I +++ +++KI T+ KD I + + I+++ D
Sbjct: 645 EIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKD 704
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFE-AVKEQCG 714
Q +N EE+T+ + E ++++ +Q + L++ +QE++ T+ E +KE+
Sbjct: 705 LQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 764
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D+ + A+ K + TL + +K + ++L L K+K+K+ +
Sbjct: 765 DLQEKFA--QLEAENSILKDEKKTLEDMLKIHTPV--SQEERLIFLDSIKSKSKDSV--W 818
Query: 775 QKKVQDIVNLEESKKQ 790
+K+++ ++ E KQ
Sbjct: 819 EKEIEILIEENEDLKQ 834
Score = 40.7 bits (91), Expect = 0.031
Identities = 74/388 (19%), Positives = 157/388 (40%), Gaps = 26/388 (6%)
Query: 614 EDLQRA-SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT-------LNETV 665
EDL+ + ++K L + L E+ L + ++E + + D Q+ L +
Sbjct: 3244 EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLL 3303
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
E + + E + +++H + D Q + + + +KE ++ + + V
Sbjct: 3304 ESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSE-DLLKELQKQLEEKHSRIVE 3362
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLE 785
+ + K K+ +L+ R + +K H K LQT E T+ ++++ Q KV+D+
Sbjct: 3363 LLNETE-KYKLDSLQTR-QQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQL 3420
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVE 845
E K+Q E+ +EK E++ ++ +N + + + +
Sbjct: 3421 EEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESR-RILYQN---LNEPTTWSLTSD 3476
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N V L +I+ K++ ++ ++ + + I Q + K+ L +
Sbjct: 3477 RTRNWV--LQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKA 3534
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE---LNEKESLIIKQTK 962
+++ ++ D++ + D Q Q KL G EE ++ S +
Sbjct: 3535 SERLQFETADDEDFIWVQENIDEIILQLQ------KLTGQQGEEPSLVSPSTSCGSLTER 3588
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEK 990
L +Q AE TG +S+L + RN + K
Sbjct: 3589 LLRQNAELTGHISQLTEEKNDLRNMVMK 3616
Score = 40.3 bits (90), Expect = 0.041
Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVY 911
+ L + QQ + R A D L KQ QI+T +Q L ++ L+D K+E
Sbjct: 236 QKLQIQFQQLQASETLRNSTHSSTAADLLQAKQ-QILTHQQQLEEQDHLLEDYQKKKE-- 292
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAEC 970
D + + Q I ++ + D+ K+ NKEE+ EKE++I + TK+ +++ +
Sbjct: 293 ----DFTMQISFLQEKIKVYEMEQDK---KVENSNKEEIQEKETIIEELNTKIIEEEKKT 345
Query: 971 TGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
ELK L L + + ++K K +L +T + K+
Sbjct: 346 L----ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE 387
Score = 34.3 bits (75), Expect = 2.7
Identities = 30/151 (19%), Positives = 76/151 (50%), Gaps = 7/151 (4%)
Query: 180 EIFDADKYSDCLDRLKKIRKDYAQNLK--LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
E+ + +K + LDR+ + ++ + L+ LL ++ + +++LE ++ N K+
Sbjct: 601 EMLEKEKNA-VLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNL 659
Query: 238 KIANEKSSNEIEYNKFILLESQNQEK---IDKRNEQIVETAKIAEIENITEVQTNEEAEN 294
I ++ + ++ +E+ EK I K+N+ I+E +K+ +++ +EE
Sbjct: 660 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 719
Query: 295 ATKTILEKVESLKSDHKVQKSQADEEEKKAQ 325
+ +++E L+ + K +K ++E ++ Q
Sbjct: 720 QINELQKEIEILRQEEK-EKGTLEQEVQELQ 749
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 59.7 bits (138), Expect = 6e-08
Identities = 95/393 (24%), Positives = 171/393 (43%), Gaps = 34/393 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
Q EK D+ Q+K L VEE IE EQ+ T D+ ++ +++ +K
Sbjct: 2023 QAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELM---DLRQQNQALEKQLEKMRK 2079
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
F + EQ +D E DV F+Q+I L ++K + Q + E +T
Sbjct: 2080 F--LDEQA--IDREHERDV-------FQQEIQKLEQQLKVV--------PRFQPISEHQT 2120
Query: 766 KAKEELLN-TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
+ E+L N ++K L SK+QLQ D + LE AL +
Sbjct: 2121 REVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQ 2180
Query: 825 EVV-RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+V R++ +EA +V++ + DA ++ K+ N+ ++E+ +E + E
Sbjct: 2181 KVEDRKHFGAVEAKPELSLEVQLQAER----DAIDRKEKEITNLEEQLEQFREELENKNE 2236
Query: 883 KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL 942
+ +Q+ ++ K+ T E+ ++ +D + L L ++D + Q Q L K
Sbjct: 2237 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ-HVLFGKF 2295
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTG--ALSELKKSLKGFRNELEKSLS-KDIEKK 999
I +E+ E + L + TKL QQ T + E + ++ ++E +S ++ K+
Sbjct: 2296 AQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKR 2355
Query: 1000 FREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
RE+ E + + I+K +E A K M H
Sbjct: 2356 NREEEIE-QLNEVIEKLQQELANIGQKTSMNAH 2387
Score = 54.4 bits (125), Expect = 2e-06
Identities = 135/683 (19%), Positives = 294/683 (43%), Gaps = 61/683 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+E+ ++ N +++ +++ E ++EL+ KI + +K+T +LK+K + L + ++ IV K
Sbjct: 322 MEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK 381
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
N+ + L N +K+ + E ++ E + E
Sbjct: 382 NQEIKNMKLELTNSKQKE------RQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 435
Query: 513 SLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTVEKLQ-----DEQNVLQS-SMFII 565
+R+ E +AE D++Y Q + ++ +E+++ + +N L+S S +
Sbjct: 436 QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITV 495
Query: 566 NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL-QRASAKKD 624
N+ + +L + + L N ++ + + L++ EDL + S ++
Sbjct: 496 NEDQIKLMNVAINEL-NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 554
Query: 625 EI-LSMKSLNEKITTLKD-----TEIPQLEKRIVDVDTQIKTL------NETVEEITMSL 672
+I + +++ E+ + L + + + L+ IV K L T +I + +
Sbjct: 555 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 614
Query: 673 IEPEQKMTTAKQIHGDMPMLDRY-IQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ-- 729
+E E+ + L+R Q + + ++ +KE D++ E +++ K
Sbjct: 615 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKE---DLEIEHRINIEKLKDNL 671
Query: 730 -VDFKQKISTLRN----RVKTTQ-KKLNAHNKKLQTLYE-KKTKAKEELLNTQKKVQDIV 782
+ +KQ+I L+N +++T Q +K N K+ Q + E K K ++ L K + +
Sbjct: 672 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 731
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
+ E +K+++ E+ LK ++ K ++ + DL E + A
Sbjct: 732 QINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEK-QMKEKENDLQEKFAQLEA 787
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPRE---MEKIQ-EANDKLMEKQKQIM-TDRQVLTKK 897
+ + ++ K+L+ ++ H + ++ I+ ++ D + EK+ +I+ + + L ++
Sbjct: 788 ENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQ 847
Query: 898 IDTLKDEIAKQEVYKRDLDDN--LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L +EI KQ + N + ++ Q + K D+L + NK+EL K
Sbjct: 848 CIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSK---NKQELEYKSK 904
Query: 956 LIIKQTKLFQQKAECTGALSELKKSL----KGFRNELEKSLSKDIEKKFREKMYELHVTK 1011
L +L Q+ T ++K S+ K F E + + +EK E M +L VTK
Sbjct: 905 LKALNEELHLQRINPTTV--KMKSSVFDEDKTFVAE-TLEMGEVVEKDTTELMEKLEVTK 961
Query: 1012 AIDKDIREYAVALDKCLMEFHRE 1034
++ + L + L + H E
Sbjct: 962 REKLELSQRLSDLSEQLKQKHGE 984
Score = 46.8 bits (106), Expect = 5e-04
Identities = 112/648 (17%), Positives = 266/648 (41%), Gaps = 71/648 (10%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDEL-SQKITKLQKQTAKLKEKEMIEENLK 442
HK ++ E +I + ++ E ++ +EQ E+DE+ Q+I +++++ + +M E +
Sbjct: 421 HKDSQFETDIVQRMEQ--ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 478
Query: 443 TKEKQLIVLKNKHKTALME---LLGNVPEKDFAVTI---NKFECEVRNEVXXXXXXXXXX 496
K + L++ + E L NV + + + N + +++ E+
Sbjct: 479 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 538
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQN 556
L E RE + R + + E K+ +A + L + + + E
Sbjct: 539 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE 598
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + K K ++ + + +R ES+ + +L K+ EDL
Sbjct: 599 LKHEAEVTNYKIKLEMLEKEKNAVLDR--MAESQEAELERLRTQLLFSHEEELSKLKEDL 656
Query: 617 Q---RASAKK----------DEILSMKS-LNEKITTL---KDTEIPQLEKRIVDV----D 655
+ R + +K +I +++ +++KI T+ KD I + + I+++ D
Sbjct: 657 EIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKD 716
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEA------- 708
Q +N EE+T+ + E ++++ +Q + L++ +QE++ T+ E
Sbjct: 717 LQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 776
Query: 709 -VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK--------TTQKKLNAHNKKLQT 759
++E+ +++E ++ K ++ KI T ++ + ++ K + K+++
Sbjct: 777 DLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEI 836
Query: 760 LYEKKTKAKEELLNTQKKVQD--------IVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
L E+ K++ + ++++ N E + ++LQ + +
Sbjct: 837 LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNK 896
Query: 812 LEVALKEKIEAKTE----------VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
E+ K K++A E V+ + + ++A+ + +V D
Sbjct: 897 QELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAET-LEMGEVVEKDTTELME 955
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
K + RE ++ + L E+ KQ + L +++ +LK E + + R+L+ +
Sbjct: 956 KLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINH 1015
Query: 922 RKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
+A+ N Q D +++ L+G+ E + K K F ++++
Sbjct: 1016 NRAE----NVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESK 1059
Score = 44.8 bits (101), Expect = 0.002
Identities = 173/905 (19%), Positives = 357/905 (39%), Gaps = 117/905 (12%)
Query: 172 KKVKERFDEIFDADKYSDCLDR-LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K +KE+ + A+K D L + +K + D + + + + K EL D ++N
Sbjct: 2012 KLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVS---RFIELEQEKNTELMDLRQQNQ 2068
Query: 231 SFNKEEEKIAN--EKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQT 288
+ K+ EK+ ++ + + E+ + + Q++I K +Q+ + + I+E QT
Sbjct: 2069 ALEKQLEKMRKFLDEQAIDREHERDVF-----QQEIQKLEQQL---KVVPRFQPISEHQT 2120
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXX 348
E E + EK + S+ + K Q + ++ +++ +
Sbjct: 2121 RE-VEQLANHLKEKTDKC-SELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADT 2178
Query: 349 XXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAEN-ELNIEECQQEINEDEKAV 407
A K+ N E +E+ ++E+ + V
Sbjct: 2179 FQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEV 2238
Query: 408 EQYEQEMD-ELSQKITKLQK--QTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLG 464
+Q +++ + + T+LQ+ Q KL + +M + L KE + +++H L G
Sbjct: 2239 QQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHV-----LFG 2293
Query: 465 NVPEKDFAVTINKFECEVR--NEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
FA I + E E+ NE +E + + IR+ E + E
Sbjct: 2294 K-----FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDL--ETQIECL 2346
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-QNVLQSSMF---IINKYKGQLKDNSCC 578
++ + C + + + + +EKLQ E N+ Q + +++ LK
Sbjct: 2347 MSDQE----CVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDV 2402
Query: 579 PLCNR-GFENESEXXXXXXXXXXXXMNVPG-KLEKVTEDL-----QRASAKKDEILSMKS 631
+ + E + E + K+ ++T++L +R S +K + + S
Sbjct: 2403 VIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENS 2462
Query: 632 LNEKITTLKDTEIPQLEKRIVDVDTQIKTL-NETV-----EEITMSLIEPEQKMTTAKQI 685
+N I L + P+LE +V + +K+L N+T E S+I E ++ Q+
Sbjct: 2463 VNVAIDHLSKDK-PELE--VVLTEDALKSLENQTYFKSFEENGKGSIINLETRLL---QL 2516
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ D E+ K+ + ++EQ G ++EM Q ++K++
Sbjct: 2517 ESTVSAKDL---ELTQCYKQIKDMQEQ-GQFETEMLQKKIVNLQKIVEEKVAA----ALV 2568
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+Q +L A + + + +T + E + +Q++ L E +L SD
Sbjct: 2569 SQIQLEAVQEYAKFCQDNQTISSEP---ERTNIQNLNQLRED--ELGSDISALTLRISEL 2623
Query: 806 XXAITPLEVAL---KEKIE-AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
+ + +L KE++E A+ V+ + + L+E + K+ + N+ K + E
Sbjct: 2624 ESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLE-----LQKL-LEGNEKKQREKE---- 2673
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQ-IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC 920
KK P+++E ++ + ++ + + L + K E+A + L + L
Sbjct: 2674 -KKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELL 2732
Query: 921 LRKA-----QTDITNWQKQDDELNEKLNGINKEELNEK---------ESLIIKQTKLFQQ 966
+++ Q D++ + E EKL+ + KE+ E E L IK +K
Sbjct: 2733 VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIAS 2792
Query: 967 KAECTGALSELKKSLK------GFRNELEKSLSKD----IEKKFREK---MYELHVTKAI 1013
+ + T +S ++ + G + L+ S + I +F EK M ELH + +
Sbjct: 2793 QTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEIL 2852
Query: 1014 DKDIR 1018
D + R
Sbjct: 2853 DMESR 2857
Score = 40.7 bits (91), Expect = 0.031
Identities = 74/388 (19%), Positives = 157/388 (40%), Gaps = 26/388 (6%)
Query: 614 EDLQRA-SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT-------LNETV 665
EDL+ + ++K L + L E+ L + ++E + + D Q+ L +
Sbjct: 3247 EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLL 3306
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
E + + E + +++H + D Q + + + +KE ++ + + V
Sbjct: 3307 ESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSE-DLLKELQKQLEEKHSRIVE 3365
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLE 785
+ + K K+ +L+ R + +K H K LQT E T+ ++++ Q KV+D+
Sbjct: 3366 LLNETE-KYKLDSLQTR-QQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQL 3423
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVE 845
E K+Q E+ +EK E++ ++ +N + + + +
Sbjct: 3424 EEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESR-RILYQN---LNEPTTWSLTSD 3479
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N V L +I+ K++ ++ ++ + + I Q + K+ L +
Sbjct: 3480 RTRNWV--LQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKA 3537
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE---LNEKESLIIKQTK 962
+++ ++ D++ + D Q Q KL G EE ++ S +
Sbjct: 3538 SERLQFETADDEDFIWVQENIDEIILQLQ------KLTGQQGEEPSLVSPSTSCGSLTER 3591
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEK 990
L +Q AE TG +S+L + RN + K
Sbjct: 3592 LLRQNAELTGHISQLTEEKNDLRNMVMK 3619
Score = 40.3 bits (90), Expect = 0.041
Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVY 911
+ L + QQ + R A D L KQ QI+T +Q L ++ L+D K+E
Sbjct: 248 QKLQIQFQQLQASETLRNSTHSSTAADLLQAKQ-QILTHQQQLEEQDHLLEDYQKKKE-- 304
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAEC 970
D + + Q I ++ + D+ K+ NKEE+ EKE++I + TK+ +++ +
Sbjct: 305 ----DFTMQISFLQEKIKVYEMEQDK---KVENSNKEEIQEKETIIEELNTKIIEEEKKT 357
Query: 971 TGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
ELK L L + + ++K K +L +T + K+
Sbjct: 358 L----ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE 399
Score = 34.3 bits (75), Expect = 2.7
Identities = 30/151 (19%), Positives = 76/151 (50%), Gaps = 7/151 (4%)
Query: 180 EIFDADKYSDCLDRLKKIRKDYAQNLK--LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
E+ + +K + LDR+ + ++ + L+ LL ++ + +++LE ++ N K+
Sbjct: 613 EMLEKEKNA-VLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNL 671
Query: 238 KIANEKSSNEIEYNKFILLESQNQEK---IDKRNEQIVETAKIAEIENITEVQTNEEAEN 294
I ++ + ++ +E+ EK I K+N+ I+E +K+ +++ +EE
Sbjct: 672 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 731
Query: 295 ATKTILEKVESLKSDHKVQKSQADEEEKKAQ 325
+ +++E L+ + K +K ++E ++ Q
Sbjct: 732 QINELQKEIEILRQEEK-EKGTLEQEVQELQ 761
>AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein.
Length = 742
Score = 59.7 bits (138), Expect = 6e-08
Identities = 102/552 (18%), Positives = 236/552 (42%), Gaps = 71/552 (12%)
Query: 390 ELNIEECQQE---INEDEKAVEQYEQEMDELSQK---ITKLQKQTAKLKEK--------- 434
E+ ++ QQE + D ++ Y E+D L +K + KL+ + ++ KE+
Sbjct: 210 EIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKA 269
Query: 435 ---EMIEENLKTKEKQLIVLKNKHKT-ALMELLGNVPEKDFAVTINKFECEVRNEVXXXX 490
E+ E+N E + ++ T A + L + +++ + + E+ ++
Sbjct: 270 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK 329
Query: 491 XXXXXXXXXXXXLEAERKHIRESLN-----ERRSELTKAEDKIYKACGTQPYDVTLSKY- 544
+ A+++ + ESL+ E+ S ++ + K+ G + ++T S+
Sbjct: 330 IEELMEENMTLEM-AQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL 388
Query: 545 ---------TTTVEKLQDEQNVLQSSMF-IINKYKGQLKDNSCCPLCNRGFENESEXXXX 594
T TVE+L+ + ++ + I+ K + + + E +
Sbjct: 389 KLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN 448
Query: 595 XXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKS--LNEKITTLKDTEIPQLEKRIV 652
M +LEK E L+ S ++ +IL ++ LN+ +++L+ E R+
Sbjct: 449 CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVK 508
Query: 653 DVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
D++ + K L+E+++E + L +I + + + ++ K ++ E ++ +
Sbjct: 509 DIEKENKILHESIKETSSKL----------SKIEFEKRQIKKELEHYKEKGERAEELENE 558
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
++ E L ++KI+ L K T +K+ A ++ L + K K+ L
Sbjct: 559 LHHLEKENEL---------LQKKITNL----KITCEKIEALEQENSELERENRKLKKTLD 605
Query: 773 NTQKKVQDIVNLEESKKQL-QSDCXXXXXXXXXXXXAITPLEVALKEK-IEAKTEVVRRN 830
+ + + +LE+ QL + + ++ ++ L+ K +E++ E +++
Sbjct: 606 SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 665
Query: 831 RDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
+L++A ++EV++ + LD E Q +K + +KIQ+ +L + + +
Sbjct: 666 LELLKASFKKTERLEVSY---QGLDIE-NQRLQKTLENSNKKIQQLESELQD----LEME 717
Query: 891 RQVLTKKIDTLK 902
Q L K ++ LK
Sbjct: 718 NQTLQKNLEELK 729
Score = 41.5 bits (93), Expect = 0.018
Identities = 84/480 (17%), Positives = 210/480 (43%), Gaps = 34/480 (7%)
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD---TQIKTLNETVEEI--T 669
D + A +DE+ +++ ++ L ++E+ + ++R+ D++ +++ L E + + T
Sbjct: 226 DARSARMYRDELDALREKAVRVDKL-ESEVSRYKERLHDIEFYKARVEELKEDNQVLLET 284
Query: 670 MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGD-----VDSEMTLDV 724
+++E + + T A+ + L++ ++K E ++ ++ MTL++
Sbjct: 285 KTMLEDQLEGTRARS--DKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEM 342
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKA---KEELLNTQ--KKVQ 779
A + +D + ++ T + A K L + T + K E+ N K V+
Sbjct: 343 AQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 402
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSA 839
++ +S + S + LE + ++ ++ ++DL++ A
Sbjct: 403 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKE-KA 461
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ-KQIMTDRQVLTKKI 898
+ K + +I + + +++ + + +++ + E + K I + ++L + I
Sbjct: 462 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 521
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLII 958
+++K E KR + L K + + + + EK N + ++++ +
Sbjct: 522 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 581
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYEL--HVTKAI 1013
K L Q+ +E +LKK+L F+N +LE SL K+ + E+ EL +V
Sbjct: 582 KIEALEQENSELERENRKLKKTLDSFKNLTFQLE-SLEKE-NSQLDEENLELRRNVESLK 639
Query: 1014 DKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESER 1073
++ + L+ +E +E+++ +++ ++K R +E+ +G L +E++R
Sbjct: 640 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTER------LEVSYQG-LDIENQR 692
Score = 39.1 bits (87), Expect = 0.094
Identities = 92/512 (17%), Positives = 196/512 (38%), Gaps = 31/512 (6%)
Query: 170 EGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKN 229
E + KER + D + Y ++ LK+ + + +LE+ +A+ +L + K+N
Sbjct: 253 EVSRYKER---LHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKEN 309
Query: 230 TSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIA-EIENITEVQT 288
+ K+ + + +++ K L +N + + + E+ + E+E I+ +T
Sbjct: 310 LQL---KAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS--RT 364
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXX 348
+E +E K++ +V L S ++ ++ K V+E R+
Sbjct: 365 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKT---VEELRTTVDSVEGNASKILKM 421
Query: 349 XXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEKAV 407
N+ K+ A+ E IE ++ K +
Sbjct: 422 EKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 481
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
EQ + +++ + + + +A+ + K++ +EN E + + K + +E
Sbjct: 482 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHES---IKETSSKLSKIEFEKRQI 538
Query: 468 EKDFAVTINKFEC--EVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE 525
+K+ K E E+ NE+ L+ + I E+L + SEL +
Sbjct: 539 KKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKI-EALEQENSELEREN 597
Query: 526 DKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGF 585
K+ K + T +E L+ E + L + + LK C +
Sbjct: 598 RKLKKTLD------SFKNLTFQLESLEKENSQLDEENLELRRNVESLK---CASMKMAQL 648
Query: 586 ENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIP 645
+ E++ + + K TE L+ S + +I + + +K + +I
Sbjct: 649 QLENKELESEKEQLKKGLELLKASFKKTERLE-VSYQGLDIENQRL--QKTLENSNKKIQ 705
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQ 677
QLE + D++ + +TL + +EE+ +S EQ
Sbjct: 706 QLESELQDLEMENQTLQKNLEELKISSKRLEQ 737
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 59.7 bits (138), Expect = 6e-08
Identities = 159/892 (17%), Positives = 336/892 (37%), Gaps = 66/892 (7%)
Query: 101 KVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCH 160
KV L K KTK + D G + C DL+ + G K S +
Sbjct: 1020 KVNTLTKAKTKLEQ-----QVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTM--D 1072
Query: 161 QEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQK 220
E+ L+E K KE F+ K D +++K + +E ++A++
Sbjct: 1073 TENDKQQLNEKLKKKE-FEMSNLQGKIEDEQALAMQLQKKIKELQARIEELEEEIEAERA 1131
Query: 221 ELEDSYKKNTSFNKEEEKI------ANEKSSNEIEYNKFILLESQNQEK-IDKRNEQIVE 273
+ K+ + ++E E+I A +S +IE NK E Q + +++ Q
Sbjct: 1132 SRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKKREAEFQKMRRDLEESTLQHEA 1191
Query: 274 TAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQ----KSQADEEEKKAQGFVD 329
TA ++ V + ++ + + +K+E KS+ K++ S + K F
Sbjct: 1192 TAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEK 1251
Query: 330 ECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXH--KQA 387
CR+ Q +S KQA
Sbjct: 1252 MCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQA 1311
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE-KEMIEENLKTKEK 446
+ IEE ++++ E+ KA + L++Q + +E K ++ +
Sbjct: 1312 FTQ-QIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANS 1370
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAE 506
++ + K++T ++ + E + + E E E E
Sbjct: 1371 EVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVE 1430
Query: 507 RKHIR-ESLNERRSELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQNVLQSSMF 563
I E N L K + K Q Y+ T ++ +E Q E L + +F
Sbjct: 1431 DLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAE----LEASQKESRSLSTELF 1486
Query: 564 II-NKYKGQLKDNSCCPLCNRGFENE----SEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
+ N Y+ L N+ + E +E V +L+ +LQ
Sbjct: 1487 KVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQT 1546
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNET---VEEITMSLIE 674
+ + + L + L+ ++ +++++I + D ++ L V E S ++
Sbjct: 1547 SLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLD 1606
Query: 675 PEQK-----MTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDV-DSEMTLDVATA 727
E + + K++ GD+ ++ + + + ++ G + D+++ LD A
Sbjct: 1607 AEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIR 1666
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VN 783
Q D K++++ + R Q ++ L+ + A++ELL+ ++VQ + +
Sbjct: 1667 GQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTS 1726
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKI---EAKTEVVRRNRDLIEAGSAY 840
L +KK+L++D E K+ I E +++ +D SA+
Sbjct: 1727 LINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDT----SAH 1782
Query: 841 IAKVEVAFNK-VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKID 899
+ +++ + VK L + + ++ + ++IQ+ ++ E + ++ ++++ + +
Sbjct: 1783 LERMKKNMEQTVKDLQLRLGEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAVK 1842
Query: 900 TLK--DEIAKQEVYKRDLDDNLCLR------KAQTDITNWQKQDDELNEKLN 943
L+ + K+ Y+ + D LR K QT + +++Q +E E+ N
Sbjct: 1843 GLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSN 1894
Score = 50.4 bits (115), Expect = 4e-05
Identities = 126/685 (18%), Positives = 273/685 (39%), Gaps = 69/685 (10%)
Query: 395 ECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNK 454
+ Q ++ + A+ E+ D+L + TK+Q + AK+KE E+ + +L K K
Sbjct: 890 DLQLQVQAEADALADAEERCDQLIK--TKIQLE-AKIKEVTERAEDEEEINAELTAKKRK 946
Query: 455 HKTALMELLGNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRES 513
+ EL ++ + + + + K + N+V L E+K ++E+
Sbjct: 947 LEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEA 1006
Query: 514 LNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLK 573
+ +L EDK+ TL+K T +E+ D+ +G L+
Sbjct: 1007 HQQTLDDLQMEEDKVN----------TLTKAKTKLEQQVDD-------------LEGSLE 1043
Query: 574 DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN 633
LC + + M+ +++ E L KK E M +L
Sbjct: 1044 QEK--KLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKL-----KKKEF-EMSNLQ 1095
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
KI + + QL+K+I ++ +I+ L E +E S + E++ + L
Sbjct: 1096 GKIEDEQALAM-QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSD----------LS 1144
Query: 694 RYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAH 753
R ++EI E ++E G +++ L+ ++ +F++ L + A
Sbjct: 1145 RELEEIS------ERLEEAGGATSAQIELN--KKREAEFQKMRRDLEESTLQHEATAAAL 1196
Query: 754 NKKLQTLYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPL 812
KK + K + L ++K++ + L+ L S+ L
Sbjct: 1197 RKKHADSVAELGKQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTL 1256
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK-VKSLDAEIQQ--HKKKNVPRE 869
E L E I+ K E +R + + A A + F++ + DA + Q K+ ++
Sbjct: 1257 EDQLSE-IKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQ 1315
Query: 870 MEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+E+++ ++ + + + Q D L+++ +++ K +L + KA +++
Sbjct: 1316 IEELKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRG--MSKANSEVA 1373
Query: 930 NWQ-KQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA-LSELKKSLKGFRNE 987
W+ K + + ++ EEL E + + ++ + ++ E + + L+K+ + +NE
Sbjct: 1374 QWRTKYETDAIQR-----TEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNE 1428
Query: 988 LEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELW 1047
+E L D+E+ + + DK + E+ ++ E + E+ ++
Sbjct: 1429 VE-DLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFK 1487
Query: 1048 RKIYRGNDIDYIEIKTEGNLTVESE 1072
K +D++E N ++ E
Sbjct: 1488 VKNAYEESLDHLETLKRENKNLQQE 1512
Score = 48.4 bits (110), Expect = 2e-04
Identities = 121/677 (17%), Positives = 263/677 (38%), Gaps = 67/677 (9%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQKI------TKLQKQTAKL 431
K E + IEE ++EI + EK +E++E+S+++ T Q + K
Sbjct: 1111 KIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIELNKK 1170
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE+ E L+ KH ++ EL + + + K + E++
Sbjct: 1171 REAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGKQIDSLQRVKQKLEKEKSELKM 1230
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ E + + + L+E + TK E++ L
Sbjct: 1231 EINDLASNMETVSKAKANFEKMCRTLEDQLSEIK---TKEEEQQRLINELSAQKARLHTE 1287
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
+ + DE++ + S + +G+ R E E++ +
Sbjct: 1288 SGEFSRQLDEKDAMVSQL-----SRGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARH 1342
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
L + E+ Q A A+ M N ++ + K D + + L E
Sbjct: 1343 DCDLLREQYEEEQEAKAELQR--GMSKANSEVAQWR-------TKYETDAIQRTEELEEA 1393
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV 724
+++ L + E+ + + ++ L++ Q ++ V++ DV+ +
Sbjct: 1394 KKKLAQRLQDAEEHV---EAVNSKCASLEKTKQRLQ------NEVEDLMIDVERSNAACI 1444
Query: 725 A-TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
A KQ +F + ++ + + + TQ +L A K+ ++L + K K ++ + +
Sbjct: 1445 ALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAY---EESLDHLET 1501
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALK----EKIEAKTEVVRRNRDLIEAGSA 839
L+ K LQ + I LE K EK E +T + L E
Sbjct: 1502 LKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASL-EHEEG 1560
Query: 840 YIAKVEVAFNKVKS-LDAEIQQHKKK--NVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
I ++++ N+VKS +D +I + ++ + R ++ E+ ++ + + D + K
Sbjct: 1561 KILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKK 1620
Query: 897 KI--DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKE 954
K+ D + EI ++ + LR Q + + Q L++ + G +++L E+
Sbjct: 1621 KMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQL---HLDDAIRG--QDDLKEQL 1675
Query: 955 SLIIKQTKLFQQKA-ECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAI 1013
+++ ++ L Q + E +L ++ K EL S+ ++ + ++ K +
Sbjct: 1676 AMVERRANLMQAEVEELRASLERTERGRKMAEQEL-LDASERVQLLHTQNTSLINTKKKL 1734
Query: 1014 DKDIREYAVALDKCLME 1030
+ DI + ++ + E
Sbjct: 1735 ETDISQIQGEMEDIVQE 1751
>AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein.
Length = 2058
Score = 59.7 bits (138), Expect = 6e-08
Identities = 95/393 (24%), Positives = 171/393 (43%), Gaps = 34/393 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
Q EK D+ Q+K L VEE IE EQ+ T D+ ++ +++ +K
Sbjct: 221 QAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELM---DLRQQNQALEKQLEKMRK 277
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
F + EQ +D E DV F+Q+I L ++K + Q + E +T
Sbjct: 278 F--LDEQA--IDREHERDV-------FQQEIQKLEQQLKVV--------PRFQPISEHQT 318
Query: 766 KAKEELLN-TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
+ E+L N ++K L SK+QLQ D + LE AL +
Sbjct: 319 REVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADTFQ 378
Query: 825 EVV-RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+V R++ +EA +V++ + DA ++ K+ N+ ++E+ +E + E
Sbjct: 379 KVEDRKHFGAVEAKPELSLEVQLQAER----DAIDRKEKEITNLEEQLEQFREELENKNE 434
Query: 883 KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL 942
+ +Q+ ++ K+ T E+ ++ +D + L L ++D + Q Q L K
Sbjct: 435 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ-HVLFGKF 493
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTG--ALSELKKSLKGFRNELEKSLS-KDIEKK 999
I +E+ E + L + TKL QQ T + E + ++ ++E +S ++ K+
Sbjct: 494 AQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKR 553
Query: 1000 FREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
RE+ E + + I+K +E A K M H
Sbjct: 554 NREEEIE-QLNEVIEKLQQELANIGQKTSMNAH 585
Score = 44.8 bits (101), Expect = 0.002
Identities = 173/905 (19%), Positives = 357/905 (39%), Gaps = 117/905 (12%)
Query: 172 KKVKERFDEIFDADKYSDCLDR-LKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K +KE+ + A+K D L + +K + D + + + + K EL D ++N
Sbjct: 210 KLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVS---RFIELEQEKNTELMDLRQQNQ 266
Query: 231 SFNKEEEKIAN--EKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQT 288
+ K+ EK+ ++ + + E+ + + Q++I K +Q+ + + I+E QT
Sbjct: 267 ALEKQLEKMRKFLDEQAIDREHERDVF-----QQEIQKLEQQL---KVVPRFQPISEHQT 318
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXX 348
E E + EK + S+ + K Q + ++ +++ +
Sbjct: 319 RE-VEQLANHLKEKTDKC-SELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSADT 376
Query: 349 XXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAEN-ELNIEECQQEINEDEKAV 407
A K+ N E +E+ ++E+ + V
Sbjct: 377 FQKVEDRKHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEV 436
Query: 408 EQYEQEMD-ELSQKITKLQK--QTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLG 464
+Q +++ + + T+LQ+ Q KL + +M + L KE + +++H L G
Sbjct: 437 QQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHV-----LFG 491
Query: 465 NVPEKDFAVTINKFECEVR--NEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
FA I + E E+ NE +E + + IR+ E + E
Sbjct: 492 K-----FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDL--ETQIECL 544
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-QNVLQSSMF---IINKYKGQLKDNSCC 578
++ + C + + + + +EKLQ E N+ Q + +++ LK
Sbjct: 545 MSDQE----CVKRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDV 600
Query: 579 PLCNR-GFENESEXXXXXXXXXXXXMNVPG-KLEKVTEDL-----QRASAKKDEILSMKS 631
+ + E + E + K+ ++T++L +R S +K + + S
Sbjct: 601 VIAEKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRERESVEKIQSIPENS 660
Query: 632 LNEKITTLKDTEIPQLEKRIVDVDTQIKTL-NETV-----EEITMSLIEPEQKMTTAKQI 685
+N I L + P+LE +V + +K+L N+T E S+I E ++ Q+
Sbjct: 661 VNVAIDHLSKDK-PELE--VVLTEDALKSLENQTYFKSFEENGKGSIINLETRLL---QL 714
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKT 745
+ D E+ K+ + ++EQ G ++EM Q ++K++
Sbjct: 715 ESTVSAKDL---ELTQCYKQIKDMQEQ-GQFETEMLQKKIVNLQKIVEEKVAA----ALV 766
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXX 805
+Q +L A + + + +T + E + +Q++ L E +L SD
Sbjct: 767 SQIQLEAVQEYAKFCQDNQTISSEP---ERTNIQNLNQLRED--ELGSDISALTLRISEL 821
Query: 806 XXAITPLEVAL---KEKIE-AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
+ + +L KE++E A+ V+ + + L+E + K+ + N+ K + E
Sbjct: 822 ESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLE-----LQKL-LEGNEKKQREKE---- 871
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQ-IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC 920
KK P+++E ++ + ++ + + L + K E+A + L + L
Sbjct: 872 -KKRSPQDVEVLKTTTELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELL 930
Query: 921 LRKA-----QTDITNWQKQDDELNEKLNGINKEELNEK---------ESLIIKQTKLFQQ 966
+++ Q D++ + E EKL+ + KE+ E E L IK +K
Sbjct: 931 VKETNMTSLQKDLSQVRDHLAEAKEKLSILEKEDETEVQESKKACMFEPLPIKLSKSIAS 990
Query: 967 KAECTGALSELKKSLK------GFRNELEKSLSKD----IEKKFREK---MYELHVTKAI 1013
+ + T +S ++ + G + L+ S + I +F EK M ELH + +
Sbjct: 991 QTDGTLKISSSNQTPQILVKNAGIQINLQSECSSEEVTEIISQFTEKIEKMQELHAAEIL 1050
Query: 1014 DKDIR 1018
D + R
Sbjct: 1051 DMESR 1055
Score = 40.7 bits (91), Expect = 0.031
Identities = 74/388 (19%), Positives = 157/388 (40%), Gaps = 26/388 (6%)
Query: 614 EDLQRA-SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKT-------LNETV 665
EDL+ + ++K L + L E+ L + ++E + + D Q+ L +
Sbjct: 1453 EDLKFSLESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLL 1512
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
E + + E + +++H + D Q + + + +KE ++ + + V
Sbjct: 1513 ESEKVRIREMSSTLDRERELHAQLQSSDGTGQSRPPLPSE-DLLKELQKQLEEKHSRIVE 1571
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLE 785
+ + K K+ +L+ R + +K H K LQT E T+ ++++ Q KV+D+
Sbjct: 1572 LLNETE-KYKLDSLQTR-QQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQL 1629
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVE 845
E K+Q E+ +EK E++ ++ +N + + + +
Sbjct: 1630 EEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESR-RILYQN---LNEPTTWSLTSD 1685
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N V L +I+ K++ ++ ++ + + I Q + K+ L +
Sbjct: 1686 RTRNWV--LQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKA 1743
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE---LNEKESLIIKQTK 962
+++ ++ D++ + D Q Q KL G EE ++ S +
Sbjct: 1744 SERLQFETADDEDFIWVQENIDEIILQLQ------KLTGQQGEEPSLVSPSTSCGSLTER 1797
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEK 990
L +Q AE TG +S+L + RN + K
Sbjct: 1798 LLRQNAELTGHISQLTEEKNDLRNMVMK 1825
>AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein.
Length = 970
Score = 59.7 bits (138), Expect = 6e-08
Identities = 72/363 (19%), Positives = 163/363 (44%), Gaps = 26/363 (7%)
Query: 610 EKVTEDLQRASAKKD-EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+K T + + S KK E+L K L K +L+D + +R+ + ++Q+ L +++
Sbjct: 307 QKQTLNARDESIKKLLEMLQSKGLPSK--SLEDDN--ERTRRMAEAESQVSHLEVILDQK 362
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
I +++ Q+ + P + +Q I+ K +++ D++ E+ + A
Sbjct: 363 EKENIHLREELHRRSQLQPE-PAKTKALQTVIEMKDTKIASLERNIRDLEDEIQMLKANG 421
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
++ + + ++ +++ + K+ L ++ +K + ELL Q K++ + N
Sbjct: 422 V-LNTEDREEEIK-QIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSD 479
Query: 788 KKQ----LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
KQ L+ + L + L+EK + ++ +DL E +
Sbjct: 480 CKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGE 539
Query: 844 VEVAFN--KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ + +VK + Q K +N+ ++ + L ++ K + TD + TL
Sbjct: 540 IRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATL 599
Query: 902 KDEIAKQEVY------KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
++ ++++E +R+ DD R+ +I +++K++ +L EK+N + + EL EKES
Sbjct: 600 EEALSEKERIIERLKEQRERDD----RERLEEIESFRKENKDLKEKVNAL-QAELTEKES 654
Query: 956 LII 958
+I
Sbjct: 655 SLI 657
Score = 58.8 bits (136), Expect = 1e-07
Identities = 148/726 (20%), Positives = 275/726 (37%), Gaps = 83/726 (11%)
Query: 214 TVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVE 273
T++A Q EL N +E E + E+ F L++++ D++ +++
Sbjct: 237 TIQALQDELRTQRDLNHLLQQESGNRGAEHFTIELTEENFRRLQAEH----DRQAKELFL 292
Query: 274 TAKIAEIENITEVQTNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECR 332
K E E ++T ++ NA ++K+ E L+S KS D+ E+ + E +
Sbjct: 293 LRKTLE-EMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRRMAEAESQ 351
Query: 333 SGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN 392
H + + K A E N
Sbjct: 352 VSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDT-----KIASLERN 406
Query: 393 IEECQQEINE-DEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEKQLIV 450
I + + EI V E +E+ Q I + + +K K + +++ L KE +L+
Sbjct: 407 IRDLEDEIQMLKANGVLNTEDREEEIKQ-IEVYKSHSKFMKTKIDQLKQELSKKESELLA 465
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
L+ K +E L N +C+ EV E + +
Sbjct: 466 LQTK-----LETLSN----------QNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRL 510
Query: 511 RESLNERRSEL---TKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINK 567
R L E+ S L TK + + GT ++ K +E + + NVLQ I
Sbjct: 511 R--LEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMK--DMLEVKERKINVLQKK---IEN 563
Query: 568 YKGQL--KDNSCCPLCNR--GFENESEXXXXXXXXXXXXMNVPGKL-EKVTEDLQRASAK 622
+ QL KD L +R + +S ++ ++ E++ E +R +
Sbjct: 564 LQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRE 623
Query: 623 K-DEILSM----KSLNEKITTLKDTEIPQLEKRIVDV--------------DTQIKTLNE 663
+ +EI S K L EK+ L+ E+ + E ++D+ D+++K+L
Sbjct: 624 RLEEIESFRKENKDLKEKVNALQ-AELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEI 682
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
+E+ + E ++ A I D M + +IK + K+ +++CG +E+
Sbjct: 683 AIEQKKEECSKLEAQLKKAHNIEDDSRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRL 742
Query: 724 VATAKQVDFKQ--KISTLRNRVKTTQKKLNAHNKKLQTL-----YEKKTKAK--EELLNT 774
+ K+V+ ++ K + T + + NKK+ L EKK A+ EE+
Sbjct: 743 LEILKEVENEKNDKDKKIAELESLTLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRR 802
Query: 775 QKKVQD---IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
+ + D + +EE L+ A T +A KE A + RR +
Sbjct: 803 EDSMADNSQHLQIEELMNALEK--TRQELDATKARLASTQQSLAEKEAHLANLRIERRKQ 860
Query: 832 --DLIE-AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+++E A +A + + L E+ KKK E+ ++ D+L+ + KQ
Sbjct: 861 LEEILEMKQEALLAAISEKDANIALL--ELSASKKKKTQEEVMALKREKDRLVHQLKQQT 918
Query: 889 TDRQVL 894
+R L
Sbjct: 919 QNRMKL 924
Score = 57.6 bits (133), Expect = 3e-07
Identities = 105/522 (20%), Positives = 211/522 (40%), Gaps = 42/522 (8%)
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGT--QPYDVTLSKYTTTVEKLQDEQNVLQSS 561
E E H+RE L+ RRS+L K KA T + D ++ + L+DE +L+++
Sbjct: 363 EKENIHLREELH-RRSQLQPEPAKT-KALQTVIEMKDTKIASLERNIRDLEDEIQMLKAN 420
Query: 562 MFIINKYKGQ-LKDNSCCPLCNRGFENE-SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
+ + + + +K ++ + + + + + KLE ++
Sbjct: 421 GVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLALQTKLETLSNQNSDC 480
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
+ + + E+ + TE+ L R+ + ++ + + ++++T E+K
Sbjct: 481 KQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLT------EEKG 534
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT--LDVATAKQVDFKQK-- 735
T A +I ML+ ++I + KK E ++EQ D D ++T D + Q D
Sbjct: 535 TLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDT 594
Query: 736 -ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL--------EE 786
++TL + ++ + ++ + ++ + E K +++ VN E
Sbjct: 595 ALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKES 654
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE--AKTEVVRRNRDLIEAGSAYIAKV 844
S L+ + LE+A+++K E +K E + IE S
Sbjct: 655 SLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLKKAHNIEDDSRM--NP 712
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD- 903
E A +++K LD E ++ E K Q D+L+E K++ ++ KKI L+
Sbjct: 713 EFA-DQIKQLDKEASYYRD-----ECGKAQAEVDRLLEILKEVENEKNDKDKKIAELESL 766
Query: 904 ---EIAKQEVYKRDLDDNLCLRKAQTD--ITNWQKQDDELNEKLNGINKEEL-NEKESLI 957
+ Q +L N L K + + ++++D + + + EEL N E
Sbjct: 767 TLRHMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTR 826
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ + A +L+E + L R E K L + +E K
Sbjct: 827 QELDATKARLASTQQSLAEKEAHLANLRIERRKQLEEILEMK 868
Score = 47.2 bits (107), Expect = 4e-04
Identities = 81/386 (20%), Positives = 165/386 (42%), Gaps = 33/386 (8%)
Query: 647 LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKF 706
LE+ + ++TQ +TLN E I L + K +K + D R + E ++
Sbjct: 297 LEEMELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDDNERTRR-MAEAESQVSHL 355
Query: 707 EAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTK 766
E + +D + ++ +++ + ++ + K Q + + K+ +L
Sbjct: 356 EVI------LDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLERNIRD 409
Query: 767 AKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV 826
++E+ K ++N E+ +++++ I L+ L +K +
Sbjct: 410 LEDEI--QMLKANGVLNTEDREEEIKQ-IEVYKSHSKFMKTKIDQLKQELSKKESELLAL 466
Query: 827 VRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK--KKNVPREMEKIQEANDKLMEKQ 884
+ L S +EV +SL A+ Q+ + V +++E L +K
Sbjct: 467 QTKLETLSNQNSDCKQHIEVL---KESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKT 523
Query: 885 KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNG 944
KQ+ Q LT++ TL EI RD+ D L +++ + ++ QK+ + L E+L
Sbjct: 524 KQL----QDLTEEKGTLAGEI-------RDMKDMLEVKERKINVL--QKKIENLQEQLRD 570
Query: 945 INKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
+K+ N K+ + QT + AL+ L+++L +E+ L + E+ RE++
Sbjct: 571 KDKQLTNLKDRVKSLQT----DSSNTDTALATLEEALSEKERIIER-LKEQRERDDRERL 625
Query: 1005 YELHVTKAIDKDIREYAVALDKCLME 1030
E+ + +KD++E AL L E
Sbjct: 626 EEIESFRKENKDLKEKVNALQAELTE 651
Score = 39.5 bits (88), Expect = 0.071
Identities = 67/284 (23%), Positives = 120/284 (42%), Gaps = 27/284 (9%)
Query: 748 KKLNAHNKKLQTLYEKKTKAKEELLNTQ-KKVQDIVNLEESK----KQLQSDCXXXXXXX 802
K+L K L+ + E + + +++ LN + + ++ ++ + +SK K L+ D
Sbjct: 288 KELFLLRKTLEEM-ELRIETQKQTLNARDESIKKLLEMLQSKGLPSKSLEDD-NERTRRM 345
Query: 803 XXXXXAITPLEVAL----KEKIEAKTEVVRRNRDLIEAGS--AYIAKVEVAFNKVKSLDA 856
++ LEV L KE I + E+ RR++ E A +E+ K+ SL+
Sbjct: 346 AEAESQVSHLEVILDQKEKENIHLREELHRRSQLQPEPAKTKALQTVIEMKDTKIASLER 405
Query: 857 EIQQHKKKNVPREMEKIQEANDKLME-KQKQIMTDRQVLTK-KIDTLKDEIAKQEVYKRD 914
I+ + + + + D+ E KQ ++ K KID LK E++K+E
Sbjct: 406 NIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQLKQELSKKESELLA 465
Query: 915 LDDNL-CLRKAQTDITNW---QKQDDELNEKLNGINKEE-------LNEKESLIIKQTKL 963
L L L +D K+ E+ I + E L EKES + K+TK
Sbjct: 466 LQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQ 525
Query: 964 FQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYEL 1007
Q E G L+ + +K E+ ++ ++KK +L
Sbjct: 526 LQDLTEEKGTLAGEIRDMKDMLEVKERKINV-LQKKIENLQEQL 568
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain (1437
AA) protein.
Length = 1437
Score = 59.3 bits (137), Expect = 8e-08
Identities = 166/901 (18%), Positives = 366/901 (40%), Gaps = 81/901 (8%)
Query: 142 MHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKE---RFDEI---FDADKYSDCLDRLK 195
+ E+L + +++++ +++ + + KK+KE R +E+ +A++ S + +
Sbjct: 578 LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRA--KAE 635
Query: 196 KIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK-----EEEKIANEKSSNEIE 249
K R D ++ L+ + E A ++E + K+ F K EE + +E +
Sbjct: 636 KQRSDLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALR 695
Query: 250 YNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLK 307
K ++ E+ID +R +Q +E K ++ +N EA + K LEK
Sbjct: 696 -KKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRS 754
Query: 308 SDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSX 367
+ +V + + EEE+ Q +++ + + ++ ++S
Sbjct: 755 LEDQVSELKTKEEEQ--QRLINDLTAQRARLQTEAGEYSRQLDEKDAL----VSQLSRSK 808
Query: 368 XXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMD---ELSQKITKL 424
+A+N L Q ++ + EQYE+E + EL + ++K
Sbjct: 809 QASTQQIEELKHQLEEETKAKNAL-AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKA 867
Query: 425 QKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDF-AVTINKFECEVR 483
+ A+ + + +T+E L K K L E +V + ++ K + ++
Sbjct: 868 NSEVAQWRTNTETDAIQRTEE--LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQ 925
Query: 484 NEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE--RRSELTKAEDKIYKACGTQPYDVTL 541
NEV L+ ++++ + L+E ++ E T+AE + + ++ L
Sbjct: 926 NEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEASQK-ESRSLSTEL 984
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX 601
K E+ D+ L+ + + L + G + E
Sbjct: 985 FKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA-----EGGKQIHELEKIKKQVEQE 1039
Query: 602 XMNVPGKLEKVTEDLQRASAK----KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQ 657
+ LE+ L+ K + E+ +KS ++ KD EI QL++ V
Sbjct: 1040 KCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRV--- 1096
Query: 658 IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEI-KTVTKKFEAVKEQCGDV 716
++T+ T++ S + K++ GD+ ++ + + + + G +
Sbjct: 1097 VETMQSTLDAEIRSR---NDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGIL 1153
Query: 717 -DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
++++ LD A Q D K++++ + R Q ++ L+ + A++ELL+
Sbjct: 1154 KETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDAS 1213
Query: 776 KKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
++VQ + +L +KK+L++D ++ L+ ++E I+ + +
Sbjct: 1214 ERVQLLHTQNTSLINTKKKLEND--------------VSQLQSEVEEVIQESRNAEEKAK 1259
Query: 832 DLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLME-KQKQIMTD 890
I +A +A+ K + A +++ KKN+ + ++ +Q D+ + K
Sbjct: 1260 KAI-TDAAMMAE---ELKKEQDTSAHLER-MKKNLEQTVKDLQHRLDEAEQLALKGGKKQ 1314
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
Q L ++ L+ E+ ++ KR+ + LRK + + Q +E ++ N + ++L
Sbjct: 1315 IQKLEARVRELEGEVENEQ--KRNAEAVKGLRKHERRVKELTYQTEE--DRKNVLRLQDL 1370
Query: 951 NEKESLIIKQTKLFQQKAE--CTGALSELKKSLKGFRNELEKS-LSKDIEKKFREKMYEL 1007
+K +K K ++AE LS+ +K E++ +++ K R K E+
Sbjct: 1371 VDKLQAKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREV 1430
Query: 1008 H 1008
H
Sbjct: 1431 H 1431
Score = 54.0 bits (124), Expect = 3e-06
Identities = 121/674 (17%), Positives = 256/674 (37%), Gaps = 60/674 (8%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQKI------TKLQKQTAKL 431
K E + IEE +EI + EK +E++E+S+++ T Q + K
Sbjct: 609 KIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQVELNKK 668
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E + L+ KH ++ EL + + + K + E++
Sbjct: 669 REAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKM 728
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E LE K SL ++ SEL E++ + D+T +
Sbjct: 729 ETDDLSSNAEAISKAKGNLE---KDGGRSLEDQVSELKTKEEEQQRLIN----DLTAQRA 781
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
E + + + + + + + E E++ +
Sbjct: 782 RLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNALAHALQSSRH 841
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
L + E+ Q A+ LS K+ +E +TE D + + L E
Sbjct: 842 DCDLLREQYEEEQEGKAELQRALS-KANSEVAQWRTNTE--------TDAIQRTEELEEA 892
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ-EIKTVTKKFEAVKEQCGDVDSEMTLD 723
+++ L E E+ + + + +Q E++ + E C +D
Sbjct: 893 KKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDK----- 947
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
KQ +F + +S + + + TQ +L A K+ ++L + K K ++ + +
Sbjct: 948 ----KQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVY---EESLDQLET 1000
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGSAY 840
L K LQ + I LE K+ + K E+ + +E
Sbjct: 1001 LRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGK 1060
Query: 841 IAKVEVAFNKVKS-LDAEIQQHKKK--NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
I ++++ N+VKS +D +I + ++ + R ++ E ++ + + D + KK
Sbjct: 1061 ILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKK 1120
Query: 898 IDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
++ +E+ Q + L LR + ++ L++ L G +E+L E+ +++
Sbjct: 1121 MEGDLNEMEIQLNHANRLAAE-SLRNYRNTQGILKETQLHLDDALRG--QEDLKEQLAIV 1177
Query: 958 IKQTKLFQQK-AECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
++ L Q + E L + ++S K EL S+ ++ + ++ K ++ D
Sbjct: 1178 ERRANLLQAEIEELWATLEQTERSRKIAEQEL-LDASERVQLLHTQNTSLINTKKKLEND 1236
Query: 1017 IREYAVALDKCLME 1030
+ + +++ + E
Sbjct: 1237 VSQLQSEVEEVIQE 1250
Score = 53.2 bits (122), Expect = 5e-06
Identities = 115/700 (16%), Positives = 280/700 (40%), Gaps = 43/700 (6%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIE-ENLKT 443
K AE E + ++E + + + + E + EL +K+ L K+ L+ + E ++L
Sbjct: 343 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 402
Query: 444 KEK---QLIVLKNKHKTALMELLGNVPEKD-FAVTINKFECEVRNEVXXXXXXXXXXXXX 499
E+ QLI K + + + E+ E++ + + ++ +E
Sbjct: 403 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 462
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E+ + E+ ++ I K ++ + T++ LQ E++ +
Sbjct: 463 LAKVEKEKHATENKVKNLTEEMAGLDETIAKL--SKEKKALQETHQQTLDDLQAEEDKVN 520
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
I+ K K +L+ E E + ++ T D +
Sbjct: 521 ----ILTKAKTKLEQQ--VDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNEND 574
Query: 620 SAKKDEILSMKS--LNEKITTLKDTEIP--QLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
+ DE L K ++ I+ ++D + QL+K+I ++ +I+ L E +E S +
Sbjct: 575 KQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKA 634
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK 735
E++ + + ++ + ++E T + ++ ++ D+ A + +
Sbjct: 635 EKQRS---DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEA-TLQHEAM 690
Query: 736 ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEESKKQLQSD 794
++ LR + + +L LQ + +K K K EL + T + + ++K L+ D
Sbjct: 691 VAALRKKHADSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKD 750
Query: 795 CXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSL 854
++ L+ +E+ ++ + L Y +++ + +L
Sbjct: 751 ------GGRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLD----EKDAL 800
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
+++ + K+ + +++E+++ ++ + + + Q D L+++ +++ K +
Sbjct: 801 VSQLSRSKQAST-QQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAE 859
Query: 915 LDDNLCLRKAQTDITNWQKQDDELNEKLNGINK-EELNEKESLIIKQTKLFQQKAECTGA 973
L L KA +++ W+ N + + I + EEL E + + ++ + ++ E A
Sbjct: 860 L--QRALSKANSEVAQWR-----TNTETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNA 912
Query: 974 -LSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ L+K+ + +NE+E L D+E+ + DK + E+ ++ E
Sbjct: 913 KCASLEKTKQRLQNEVE-DLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELE 971
Query: 1033 REKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESE 1072
+ E+ ++ K +D +E N ++ E
Sbjct: 972 ASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQE 1011
Score = 50.0 bits (114), Expect = 5e-05
Identities = 41/164 (25%), Positives = 82/164 (50%), Gaps = 9/164 (5%)
Query: 879 KLMEKQKQIMTDRQVLTKK--IDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDI-TNWQKQ 934
K+ K T++++ T K KDE+AK E +++L++ + L K + D+ Q +
Sbjct: 337 KIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSE 396
Query: 935 DDEL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
D L E+ + K ++ + E+ I + T+ +++ E L+ K+ L+ +EL+K
Sbjct: 397 ADSLADAEERCEQLIKNKI-QLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKD 455
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
+ D+E + E H T+ K++ E LD+ + + +EK
Sbjct: 456 ID-DLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEK 498
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 59.3 bits (137), Expect = 8e-08
Identities = 137/667 (20%), Positives = 273/667 (40%), Gaps = 88/667 (13%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK-------QTAKL-KEKEM 436
K A+ L++EE ++ E+E A ++ + E KI KL+ Q KL KE+++
Sbjct: 61 KMAQQMLDLEE---QLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKL 117
Query: 437 IEENL----------KTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEV 486
+EE + + K K L LKNKH++ + EL + +++ K E+
Sbjct: 118 LEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEE------KSRQELEKLK 171
Query: 487 XXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTT 546
L+A+ ++ L ++ EL A ++ + + L K
Sbjct: 172 RKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQK--NNALKKIRE 229
Query: 547 TVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP 606
+ D Q L S NK + Q +D G E E+ +
Sbjct: 230 LEGHISDLQEDLDSERAARNKAEKQKRD--------LGEELEA-----------LKTELE 270
Query: 607 GKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
L+ + + ++ E+ +K ++ T + ++ ++ ++ ++ L E +E
Sbjct: 271 DTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQA---VEELTEQLE 327
Query: 667 EITMSLIE-PEQKMTTAKQ---IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
+ + + K T K+ + G++ +L + QE++ KK EA Q ++ S+ +
Sbjct: 328 QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEA---QVQELQSKCS- 383
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
D A+ + K+ L+N V++ LN K L + +L +TQ+ +Q
Sbjct: 384 DGERAR-AELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQ--- 439
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE++++L L+ L E++EAK + R L S
Sbjct: 440 --EETRQKLN-----VSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 492
Query: 843 KVEVAFNKVKSLDAEIQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
K++ + V++L+ ++ +K +N+ ++ E+ A DKL + + ++ + L +D
Sbjct: 493 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 552
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
+ ++ E +R D L K +I++ K DE + + E EKE+ +
Sbjct: 553 QRQLVSNLEKKQRKFDQLLAEEK---NISS--KYADERDRA-----EAEAREKETKALSL 602
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK-AIDKDIRE 1019
+ ++ E L K LK +L S D+ K ++EL +K A++ + E
Sbjct: 603 ARALEEALEAKEELERTNKMLKAEMEDLVSS-KDDVGK----NVHELEKSKRALETQMEE 657
Query: 1020 YAVALDK 1026
L++
Sbjct: 658 MKTQLEE 664
Score = 58.0 bits (134), Expect = 2e-07
Identities = 170/933 (18%), Positives = 378/933 (40%), Gaps = 80/933 (8%)
Query: 173 KVKERFDEIFDADKYSDCLDRLKKIRK----DYAQNLKLLENYATTV-KAKQK------E 221
K+K+ DEI D ++ L + +K+ + D NL E A + K K K E
Sbjct: 93 KIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISE 152
Query: 222 LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFIL-LESQNQE---KIDKRNEQIVETAKI 277
LE KK +E EK+ + + ++++ I L++Q E ++ K+ E++ A +
Sbjct: 153 LEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL--QAAL 210
Query: 278 AEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
A +++ E+ A + + + L+ D +++ ++ EK+ + +E + T+
Sbjct: 211 ARLDD--EIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTE 268
Query: 338 XXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN--IEE 395
H QA EL +E+
Sbjct: 269 LEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQ 328
Query: 396 CQQEINEDEKAVEQYEQEMDELSQKITKL----QKQTAKLKEKEMIEENLKTK----EKQ 447
++ +K + E+E +L+ ++ L Q+ K K+ E + L++K E+
Sbjct: 329 FKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERA 388
Query: 448 LIVLKNK-HK--TALMELLGNVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L +K HK + + G + E + A+ + K + +++ +
Sbjct: 389 RAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNV 448
Query: 504 EAERKHIRE---SLNERRSELTKAEDKIYKACGTQPYDVTLSK-----YTTTVEKLQDEQ 555
+ + + E SL ++ E +A+ + + T ++ SK + +TVE L++ +
Sbjct: 449 STKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGK 508
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
Q I Q ++ + ++ + + ++ +
Sbjct: 509 KRFQKE---IENLTQQYEEKAAA------YDKLEKTKNRLQQELDDLVVDLDNQRQLVSN 559
Query: 616 LQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVEEIT-- 669
L++ K D++L+ K+++ K +D E + E + + + ++ E EE+
Sbjct: 560 LEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERT 619
Query: 670 --MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
M E E +++ + ++ L++ + ++T ++ + E+ D + + + D
Sbjct: 620 NKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQASEDAKLR 678
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDIVNLEE 786
+V+ + ++ ++ ++LQ L+E +T+ ++E LE
Sbjct: 679 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLEG 738
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
K L+ + L+ +K+ + + E R +RD I A + K
Sbjct: 739 DLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELEDARASRDEIFATAKENEK--- 794
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKIDTLKDE 904
K KSL+A++ Q ++ E + Q +K L E+ ++ R L + L+
Sbjct: 795 ---KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEAR 851
Query: 905 IAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESLIIKQT 961
IA+ E +L++ +A +D + +Q ++L NE + + NE + +Q
Sbjct: 852 IAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQN 908
Query: 962 KLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
K + K E GA+ S+ K ++ ++ + L + +E++ REK K DK ++E
Sbjct: 909 KELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKDKKLKE 967
Query: 1020 YAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
+ + ++ + E ++E+ E N +++L R++
Sbjct: 968 ILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 1000
Score = 50.4 bits (115), Expect = 4e-05
Identities = 139/825 (16%), Positives = 321/825 (38%), Gaps = 68/825 (8%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKA 151
+ L+ R+ + A +K+ + L++ + +++ T D ++ +L +E+ V K
Sbjct: 239 EDLDSERAARNKAEKQKRDLGEELEALKTELED---TLDSTATQQELRAKREQEVTVLKK 295
Query: 152 ILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC-LDR----LKKIRKDYAQNLK 206
L+ H+ + + E E + K + LD+ L+K D A L+
Sbjct: 296 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 355
Query: 207 LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE------KSSNEIEYNKFILLESQN 260
+L V+ K+K+LE ++ S + E+ E K NE+E +L E++
Sbjct: 356 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 415
Query: 261 QEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEE 320
+ I + ++++ + + + + +T ++ +TK + L+ + + Q DEE
Sbjct: 416 KA-IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK-----LRQLEEERNSLQDQLDEE 469
Query: 321 EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXX 380
+ Q + + Q +
Sbjct: 470 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 529
Query: 381 XXXHKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIE 438
K + +++ +++ + V E++ + Q + + + ++K E++ E
Sbjct: 530 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 589
Query: 439 ENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXX 497
+ KE + + L AL E L E + + K E E + +
Sbjct: 590 AEAREKETKALSLAR----ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 645
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAED-KIYKACGTQPYDVTLSK-YTTTVEKLQDEQ 555
LE + + ++ L E EL +ED K+ Q + E+ ++++
Sbjct: 646 KSKRALETQMEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 705
Query: 556 NVLQSSMFIINKYKGQLKDN----SCCPLCNRGFENESEXXXXXXXXXXX----XMNVPG 607
LQ + ++Y+ +L+D + + E + + +
Sbjct: 706 RQLQRQL---HEYETELEDERNERALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 762
Query: 608 KLEKVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNE 663
KL+ +D QR A A +DEI + NEK + ++ QL++ + + K +
Sbjct: 763 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL 822
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTL 722
EE+ L A + G + D + + + E ++E+ G++++ +
Sbjct: 823 EKEELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRV 873
Query: 723 DVATAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKV 778
AT + +++T R+ + ++ +++L NK+L++ L+E + K + +T
Sbjct: 874 RKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST---- 929
Query: 779 QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIE 835
I LE QL+ ++ + LKE ++E + ++ + ++ E
Sbjct: 930 --IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAE 987
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
G+A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 988 KGNARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 1031
>AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1007
Score = 59.3 bits (137), Expect = 8e-08
Identities = 148/825 (17%), Positives = 310/825 (37%), Gaps = 48/825 (5%)
Query: 192 DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
+ L++ ++ A NL + +++A K+LE K KE KI K S+
Sbjct: 160 EELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSD----- 214
Query: 252 KFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHK 311
F L S+ +EK+ + +++ + ++AE +Q +E+E + ++E LKS
Sbjct: 215 -FQCL-SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVT 272
Query: 312 VQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXX 371
Q+ + +++ +E H N
Sbjct: 273 SQQQEMAVLDRQLGHKKEEL---HLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKS 329
Query: 372 XXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQK 426
+ Q +E + + +QEI ++E+ + Q + EL + LQ
Sbjct: 330 LLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQL 389
Query: 427 QTAKLKE-KEMIEENLKTKEK-QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRN 484
+ +L+ K ++ + EK Q+ VL+ K + ++ + + + E + R
Sbjct: 390 ENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKR- 448
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ L E++ ++E + +L A+ K A + + S
Sbjct: 449 EIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKL--AQTKRVLAAAEENSKMEQS-- 504
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
+EKL+ LQ + +N+ K L ++ + + E N
Sbjct: 505 --NLEKLELNVRKLQQELDQLNRDKLSLHND-----ISAMQQQLQEKREAVNSLQEELAN 557
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
V L +DL + +D +LS ++ +K + +K Q++ L
Sbjct: 558 VQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNE 617
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV 724
+EE + L++ E ++ +R +E K T K +KEQ ++ E+T
Sbjct: 618 IEENKLKLVQQEMMFQRLQK--------ERESEESKLETSKV-TLKEQQHQLEKELTDQK 668
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ QV K+ RV+T Q++ +TL + K + E +K +++ L
Sbjct: 669 SKLDQV--LSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLAL 726
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
++ +++D +LKE ++ + + +N + ++ I K
Sbjct: 727 QKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQK- 785
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
E+A ++ + D + + +M+ K M QK + + ++ + TLK E
Sbjct: 786 EMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSE 845
Query: 905 IAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE---ELNE---KESLII 958
+ K E+ + N L + D+ ++++ L +L + + +NE +E L
Sbjct: 846 V-KDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNF 904
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
Q + + +L+ + +L +SK E + K
Sbjct: 905 SQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGK 949
Score = 57.6 bits (133), Expect = 3e-07
Identities = 125/682 (18%), Positives = 291/682 (42%), Gaps = 64/682 (9%)
Query: 388 ENELNIEECQQEINE---DEKAVEQYEQEMDELSQKITKL--QKQT---AKLKEKEMIEE 439
E +N+ + Q++ D K +EQ++ + +E+ ++I K+ K + K+KE + E
Sbjct: 168 ETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTE 227
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
L+ +K + + + L L K+ V + R E+
Sbjct: 228 ELQKLQKDIEMAERNEDHHLQVL------KESEVLLQA----KRAELEKLKSQVTSQQQE 277
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS-KYTTTVEKLQDEQNVL 558
L+ + H +E L+ + + +A+ + +A +VT + V+ L +E +
Sbjct: 278 MAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQ 337
Query: 559 QSSMFI-INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQ 617
+ + + I++ K QL L + E E E +L+ + + LQ
Sbjct: 338 KGELNVQISERKTQLT------LIKQEIEKEEENLQVVLRQMSKHKT---ELKNILDMLQ 388
Query: 618 RASAKKDEILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
+ E+ +K +++++ L+ T++ LE+++ +++ L + ++ + +
Sbjct: 389 ---LENHELQGLKLQHDQRVSELEKTQVAVLEEKL-----ELENLQQISQQQKGEIEWQK 440
Query: 677 QKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEM--TLDVATAKQVDFK 733
Q + K+ M R +Q ++ ++K+ E ++E+C + ++ T V A + + K
Sbjct: 441 QLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSK 500
Query: 734 QKISTLRN---RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV----QDIVNLEE 786
+ S L V+ Q++L+ N+ +L+ + +++L ++ V +++ N+++
Sbjct: 501 MEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD 560
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ D T L+ + E + E ++ + + + + E+
Sbjct: 561 HLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN-RFEDCQKEEETKQQ-QLQVLQNEI 618
Query: 847 AFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
NK+K + E+ Q +K E K++ + L E+Q Q+ + K+D + ++
Sbjct: 619 EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 678
Query: 906 AKQEVYKRDL--DDNLC------LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
E R L ++ C L + + ++ ++Q E + +L + KE + +
Sbjct: 679 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 738
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK--MYELHVTKAIDK 1015
+ + + ++ + ++ LK++LK R++LEK+L +E+K E+ + + +
Sbjct: 739 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNL---LEQKQENSCIQKEMATIELVAQ 795
Query: 1016 DIREYAVALDKCLMEFHREKME 1037
D E A L K L + E E
Sbjct: 796 DNHERARRLMKELNQMQYEYTE 817
Score = 36.7 bits (81), Expect = 0.50
Identities = 66/376 (17%), Positives = 149/376 (39%), Gaps = 14/376 (3%)
Query: 605 VPGKLEKVTEDLQRASAKK--DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+ G +E + +L+ + K ++I+ EK + +E+ + ++ + + ++++
Sbjct: 63 IDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTK 122
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E V + + + ++ L + + + + ++ + D ++
Sbjct: 123 EKVCLLVVWGVSSVWTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRS 182
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ--- 779
A AK ++ + KI +K K + A + Q L +KK K EEL QK ++
Sbjct: 183 LQADAKDLE-QHKIKQ-EEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 240
Query: 780 -----DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLI 834
+ L+ES+ LQ+ + V ++ K E+ ++
Sbjct: 241 RNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMV 300
Query: 835 EAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVL 894
+A + + + +V I++ K +K E N ++ E++ Q+ +Q +
Sbjct: 301 QAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK-GELNVQISERKTQLTLIKQEI 359
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEK 953
K+ + L+ + + +K +L + L L+ ++ + Q D+ +L L EK
Sbjct: 360 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 419
Query: 954 ESLIIKQTKLFQQKAE 969
L Q QQK E
Sbjct: 420 LELENLQQISQQQKGE 435
>AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1773
Score = 59.3 bits (137), Expect = 8e-08
Identities = 148/825 (17%), Positives = 310/825 (37%), Gaps = 48/825 (5%)
Query: 192 DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
+ L++ ++ A NL + +++A K+LE K KE KI K S+
Sbjct: 926 EELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSD----- 980
Query: 252 KFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHK 311
F L S+ +EK+ + +++ + ++AE +Q +E+E + ++E LKS
Sbjct: 981 -FQCL-SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVT 1038
Query: 312 VQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXX 371
Q+ + +++ +E H N
Sbjct: 1039 SQQQEMAVLDRQLGHKKEEL---HLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKS 1095
Query: 372 XXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQK 426
+ Q +E + + +QEI ++E+ + Q + EL + LQ
Sbjct: 1096 LLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQL 1155
Query: 427 QTAKLKE-KEMIEENLKTKEK-QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRN 484
+ +L+ K ++ + EK Q+ VL+ K + ++ + + + E + R
Sbjct: 1156 ENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKR- 1214
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ L E++ ++E + +L A+ K A + + S
Sbjct: 1215 EIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKL--AQTKRVLAAAEENSKMEQS-- 1270
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
+EKL+ LQ + +N+ K L ++ + + E N
Sbjct: 1271 --NLEKLELNVRKLQQELDQLNRDKLSLHND-----ISAMQQQLQEKREAVNSLQEELAN 1323
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
V L +DL + +D +LS ++ +K + +K Q++ L
Sbjct: 1324 VQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNE 1383
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV 724
+EE + L++ E ++ +R +E K T K +KEQ ++ E+T
Sbjct: 1384 IEENKLKLVQQEMMFQRLQK--------ERESEESKLETSKV-TLKEQQHQLEKELTDQK 1434
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ QV K+ RV+T Q++ +TL + K + E +K +++ L
Sbjct: 1435 SKLDQV--LSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLAL 1492
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
++ +++D +LKE ++ + + +N + ++ I K
Sbjct: 1493 QKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQK- 1551
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
E+A ++ + D + + +M+ K M QK + + ++ + TLK E
Sbjct: 1552 EMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSE 1611
Query: 905 IAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE---ELNE---KESLII 958
+ K E+ + N L + D+ ++++ L +L + + +NE +E L
Sbjct: 1612 V-KDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNF 1670
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
Q + + +L+ + +L +SK E + K
Sbjct: 1671 SQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGK 1715
Score = 57.6 bits (133), Expect = 3e-07
Identities = 125/682 (18%), Positives = 291/682 (42%), Gaps = 64/682 (9%)
Query: 388 ENELNIEECQQEINE---DEKAVEQYEQEMDELSQKITKL--QKQT---AKLKEKEMIEE 439
E +N+ + Q++ D K +EQ++ + +E+ ++I K+ K + K+KE + E
Sbjct: 934 ETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTE 993
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
L+ +K + + + L L K+ V + R E+
Sbjct: 994 ELQKLQKDIEMAERNEDHHLQVL------KESEVLLQA----KRAELEKLKSQVTSQQQE 1043
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS-KYTTTVEKLQDEQNVL 558
L+ + H +E L+ + + +A+ + +A +VT + V+ L +E +
Sbjct: 1044 MAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQ 1103
Query: 559 QSSMFI-INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQ 617
+ + + I++ K QL L + E E E +L+ + + LQ
Sbjct: 1104 KGELNVQISERKTQLT------LIKQEIEKEEENLQVVLRQMSKHKT---ELKNILDMLQ 1154
Query: 618 RASAKKDEILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
+ E+ +K +++++ L+ T++ LE+++ +++ L + ++ + +
Sbjct: 1155 ---LENHELQGLKLQHDQRVSELEKTQVAVLEEKL-----ELENLQQISQQQKGEIEWQK 1206
Query: 677 QKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEM--TLDVATAKQVDFK 733
Q + K+ M R +Q ++ ++K+ E ++E+C + ++ T V A + + K
Sbjct: 1207 QLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSK 1266
Query: 734 QKISTLRN---RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV----QDIVNLEE 786
+ S L V+ Q++L+ N+ +L+ + +++L ++ V +++ N+++
Sbjct: 1267 MEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD 1326
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ D T L+ + E + E ++ + + + + E+
Sbjct: 1327 HLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN-RFEDCQKEEETKQQ-QLQVLQNEI 1384
Query: 847 AFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
NK+K + E+ Q +K E K++ + L E+Q Q+ + K+D + ++
Sbjct: 1385 EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1444
Query: 906 AKQEVYKRDL--DDNLC------LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
E R L ++ C L + + ++ ++Q E + +L + KE + +
Sbjct: 1445 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 1504
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK--MYELHVTKAIDK 1015
+ + + ++ + ++ LK++LK R++LEK+L +E+K E+ + + +
Sbjct: 1505 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNL---LEQKQENSCIQKEMATIELVAQ 1561
Query: 1016 DIREYAVALDKCLMEFHREKME 1037
D E A L K L + E E
Sbjct: 1562 DNHERARRLMKELNQMQYEYTE 1583
Score = 38.7 bits (86), Expect = 0.12
Identities = 72/376 (19%), Positives = 150/376 (39%), Gaps = 27/376 (7%)
Query: 605 VPGKLEKVTEDLQRASAKK--DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+ G +E + +L+ + K ++I+ EK + +E+ + ++ + + ++++
Sbjct: 842 IDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTK 901
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E + + ++ + Q D L+R QE T +A D ++
Sbjct: 902 EKTKNAVEKFTDAKRSLL---QTESDAEELERRAQE--TAVNLVKA--------DQQLRS 948
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ--- 779
A AK ++ + KI +K K + A + Q L +KK K EEL QK ++
Sbjct: 949 LQADAKDLE-QHKIKQ-EEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 1006
Query: 780 -----DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLI 834
+ L+ES+ LQ+ + V ++ K E+ ++
Sbjct: 1007 RNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMV 1066
Query: 835 EAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVL 894
+A + + + +V I++ K +K E N ++ E++ Q+ +Q +
Sbjct: 1067 QAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK-GELNVQISERKTQLTLIKQEI 1125
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEK 953
K+ + L+ + + +K +L + L L+ ++ + Q D+ +L L EK
Sbjct: 1126 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1185
Query: 954 ESLIIKQTKLFQQKAE 969
L Q QQK E
Sbjct: 1186 LELENLQQISQQQKGE 1201
>AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110kDa
protein.
Length = 2325
Score = 59.3 bits (137), Expect = 8e-08
Identities = 148/825 (17%), Positives = 310/825 (37%), Gaps = 48/825 (5%)
Query: 192 DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
+ L++ ++ A NL + +++A K+LE K KE KI K S+
Sbjct: 1478 EELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSD----- 1532
Query: 252 KFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHK 311
F L S+ +EK+ + +++ + ++AE +Q +E+E + ++E LKS
Sbjct: 1533 -FQCL-SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVT 1590
Query: 312 VQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXX 371
Q+ + +++ +E H N
Sbjct: 1591 SQQQEMAVLDRQLGHKKEEL---HLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKS 1647
Query: 372 XXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQK 426
+ Q +E + + +QEI ++E+ + Q + EL + LQ
Sbjct: 1648 LLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQL 1707
Query: 427 QTAKLKE-KEMIEENLKTKEK-QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRN 484
+ +L+ K ++ + EK Q+ VL+ K + ++ + + + E + R
Sbjct: 1708 ENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKR- 1766
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ L E++ ++E + +L A+ K A + + S
Sbjct: 1767 EIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKL--AQTKRVLAAAEENSKMEQS-- 1822
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
+EKL+ LQ + +N+ K L ++ + + E N
Sbjct: 1823 --NLEKLELNVRKLQQELDQLNRDKLSLHND-----ISAMQQQLQEKREAVNSLQEELAN 1875
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
V L +DL + +D +LS ++ +K + +K Q++ L
Sbjct: 1876 VQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNE 1935
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV 724
+EE + L++ E ++ +R +E K T K +KEQ ++ E+T
Sbjct: 1936 IEENKLKLVQQEMMFQRLQK--------ERESEESKLETSKV-TLKEQQHQLEKELTDQK 1986
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ QV K+ RV+T Q++ +TL + K + E +K +++ L
Sbjct: 1987 SKLDQV--LSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLAL 2044
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
++ +++D +LKE ++ + + +N + ++ I K
Sbjct: 2045 QKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQK- 2103
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
E+A ++ + D + + +M+ K M QK + + ++ + TLK E
Sbjct: 2104 EMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSE 2163
Query: 905 IAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE---ELNE---KESLII 958
+ K E+ + N L + D+ ++++ L +L + + +NE +E L
Sbjct: 2164 V-KDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNF 2222
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
Q + + +L+ + +L +SK E + K
Sbjct: 2223 SQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGK 2267
Score = 57.6 bits (133), Expect = 3e-07
Identities = 125/682 (18%), Positives = 291/682 (42%), Gaps = 64/682 (9%)
Query: 388 ENELNIEECQQEINE---DEKAVEQYEQEMDELSQKITKL--QKQT---AKLKEKEMIEE 439
E +N+ + Q++ D K +EQ++ + +E+ ++I K+ K + K+KE + E
Sbjct: 1486 ETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTE 1545
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
L+ +K + + + L L K+ V + R E+
Sbjct: 1546 ELQKLQKDIEMAERNEDHHLQVL------KESEVLLQA----KRAELEKLKSQVTSQQQE 1595
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS-KYTTTVEKLQDEQNVL 558
L+ + H +E L+ + + +A+ + +A +VT + V+ L +E +
Sbjct: 1596 MAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQ 1655
Query: 559 QSSMFI-INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQ 617
+ + + I++ K QL L + E E E +L+ + + LQ
Sbjct: 1656 KGELNVQISERKTQLT------LIKQEIEKEEENLQVVLRQMSKHKT---ELKNILDMLQ 1706
Query: 618 RASAKKDEILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
+ E+ +K +++++ L+ T++ LE+++ +++ L + ++ + +
Sbjct: 1707 ---LENHELQGLKLQHDQRVSELEKTQVAVLEEKL-----ELENLQQISQQQKGEIEWQK 1758
Query: 677 QKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEM--TLDVATAKQVDFK 733
Q + K+ M R +Q ++ ++K+ E ++E+C + ++ T V A + + K
Sbjct: 1759 QLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSK 1818
Query: 734 QKISTLRN---RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV----QDIVNLEE 786
+ S L V+ Q++L+ N+ +L+ + +++L ++ V +++ N+++
Sbjct: 1819 MEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD 1878
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ D T L+ + E + E ++ + + + + E+
Sbjct: 1879 HLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN-RFEDCQKEEETKQQ-QLQVLQNEI 1936
Query: 847 AFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
NK+K + E+ Q +K E K++ + L E+Q Q+ + K+D + ++
Sbjct: 1937 EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1996
Query: 906 AKQEVYKRDL--DDNLC------LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
E R L ++ C L + + ++ ++Q E + +L + KE + +
Sbjct: 1997 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 2056
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK--MYELHVTKAIDK 1015
+ + + ++ + ++ LK++LK R++LEK+L +E+K E+ + + +
Sbjct: 2057 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNL---LEQKQENSCIQKEMATIELVAQ 2113
Query: 1016 DIREYAVALDKCLMEFHREKME 1037
D E A L K L + E E
Sbjct: 2114 DNHERARRLMKELNQMQYEYTE 2135
Score = 50.0 bits (114), Expect = 5e-05
Identities = 80/394 (20%), Positives = 181/394 (45%), Gaps = 33/394 (8%)
Query: 616 LQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
+Q + DE L +N + T DT++ EK+I T++ L++ +E+ ++
Sbjct: 411 VQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRA 470
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK 735
++ KQ+ + L + + K + K + + Q + + LD+ + KQ+
Sbjct: 471 TEEF---KQLE-EAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQ-KQE 525
Query: 736 ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDC 795
I+ + +K Q +++ L + K + K + ++++ DI+N + +QL+S
Sbjct: 526 IAGKQKEIKDLQIAIDS----LDSKDPKHSHMKAQKSGKEQQL-DIMN--KQYQQLESRL 578
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG-SAYIAKVEVAFNKVKSL 854
I LE L E A E ++++ + + +G Y+ ++ + ++
Sbjct: 579 DEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNE 638
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
+++ K+ + R + ++++ D+L + + D + + K++ L+ + +Q
Sbjct: 639 CRKLRDEKETLLQR-LTEVEQERDQL----EIVAMDAENMRKELAELESALQEQH----- 688
Query: 915 LDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGAL 974
+ N L++ Q D++ ++ EL +LN + E N+ + + K T+L Q E +
Sbjct: 689 -EVNASLQQTQGDLSAYEA---ELEARLN-LRDAEANQLKEELEKVTRLTQ--LEQSALQ 741
Query: 975 SELKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
+EL+K + +N L K ++ E+K +E ELH
Sbjct: 742 AELEKERQALKNALGK--AQFSEEKEQENS-ELH 772
Score = 38.7 bits (86), Expect = 0.12
Identities = 72/376 (19%), Positives = 150/376 (39%), Gaps = 27/376 (7%)
Query: 605 VPGKLEKVTEDLQRASAKK--DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+ G +E + +L+ + K ++I+ EK + +E+ + ++ + + ++++
Sbjct: 1394 IDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTK 1453
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E + + ++ + Q D L+R QE T +A D ++
Sbjct: 1454 EKTKNAVEKFTDAKRSLL---QTESDAEELERRAQE--TAVNLVKA--------DQQLRS 1500
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ--- 779
A AK ++ + KI +K K + A + Q L +KK K EEL QK ++
Sbjct: 1501 LQADAKDLE-QHKIKQ-EEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 1558
Query: 780 -----DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLI 834
+ L+ES+ LQ+ + V ++ K E+ ++
Sbjct: 1559 RNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMV 1618
Query: 835 EAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVL 894
+A + + + +V I++ K +K E N ++ E++ Q+ +Q +
Sbjct: 1619 QAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK-GELNVQISERKTQLTLIKQEI 1677
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEK 953
K+ + L+ + + +K +L + L L+ ++ + Q D+ +L L EK
Sbjct: 1678 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1737
Query: 954 ESLIIKQTKLFQQKAE 969
L Q QQK E
Sbjct: 1738 LELENLQQISQQQKGE 1753
Score = 37.1 bits (82), Expect = 0.38
Identities = 37/161 (22%), Positives = 80/161 (49%), Gaps = 12/161 (7%)
Query: 172 KKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKL-LENYATTVKAKQKELEDSYKKNT 230
KK+ E ++ + S L + K+R++ A +L+L +E + KQKE++D
Sbjct: 484 KKISEAGKDLL-YKQLSGRLQLVNKLRQE-ALDLELQMEKQKQEIAGKQKEIKDLQIAID 541
Query: 231 SFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIV-----ETAKIAEI-ENIT 284
S + ++ K ++ K+ + + ++ Q Q+ ++ R ++I+ ET +I ++ E +T
Sbjct: 542 SLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQ-LESRLDEILSRIAKETEEIKDLEEQLT 600
Query: 285 E--VQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKK 323
E + NE + + ++ ++ K Q +QA E +K
Sbjct: 601 EGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRK 641
>AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein.
Length = 1793
Score = 59.3 bits (137), Expect = 8e-08
Identities = 148/825 (17%), Positives = 310/825 (37%), Gaps = 48/825 (5%)
Query: 192 DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
+ L++ ++ A NL + +++A K+LE K KE KI K S+
Sbjct: 946 EELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSD----- 1000
Query: 252 KFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHK 311
F L S+ +EK+ + +++ + ++AE +Q +E+E + ++E LKS
Sbjct: 1001 -FQCL-SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVT 1058
Query: 312 VQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXX 371
Q+ + +++ +E H N
Sbjct: 1059 SQQQEMAVLDRQLGHKKEEL---HLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKS 1115
Query: 372 XXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQK 426
+ Q +E + + +QEI ++E+ + Q + EL + LQ
Sbjct: 1116 LLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQL 1175
Query: 427 QTAKLKE-KEMIEENLKTKEK-QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRN 484
+ +L+ K ++ + EK Q+ VL+ K + ++ + + + E + R
Sbjct: 1176 ENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKR- 1234
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ L E++ ++E + +L A+ K A + + S
Sbjct: 1235 EIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKL--AQTKRVLAAAEENSKMEQS-- 1290
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
+EKL+ LQ + +N+ K L ++ + + E N
Sbjct: 1291 --NLEKLELNVRKLQQELDQLNRDKLSLHND-----ISAMQQQLQEKREAVNSLQEELAN 1343
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
V L +DL + +D +LS ++ +K + +K Q++ L
Sbjct: 1344 VQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNE 1403
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV 724
+EE + L++ E ++ +R +E K T K +KEQ ++ E+T
Sbjct: 1404 IEENKLKLVQQEMMFQRLQK--------ERESEESKLETSKV-TLKEQQHQLEKELTDQK 1454
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ QV K+ RV+T Q++ +TL + K + E +K +++ L
Sbjct: 1455 SKLDQV--LSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLAL 1512
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
++ +++D +LKE ++ + + +N + ++ I K
Sbjct: 1513 QKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQK- 1571
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
E+A ++ + D + + +M+ K M QK + + ++ + TLK E
Sbjct: 1572 EMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSE 1631
Query: 905 IAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE---ELNE---KESLII 958
+ K E+ + N L + D+ ++++ L +L + + +NE +E L
Sbjct: 1632 V-KDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNF 1690
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
Q + + +L+ + +L +SK E + K
Sbjct: 1691 SQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGK 1735
Score = 57.6 bits (133), Expect = 3e-07
Identities = 125/682 (18%), Positives = 291/682 (42%), Gaps = 64/682 (9%)
Query: 388 ENELNIEECQQEINE---DEKAVEQYEQEMDELSQKITKL--QKQT---AKLKEKEMIEE 439
E +N+ + Q++ D K +EQ++ + +E+ ++I K+ K + K+KE + E
Sbjct: 954 ETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTE 1013
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
L+ +K + + + L L K+ V + R E+
Sbjct: 1014 ELQKLQKDIEMAERNEDHHLQVL------KESEVLLQA----KRAELEKLKSQVTSQQQE 1063
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS-KYTTTVEKLQDEQNVL 558
L+ + H +E L+ + + +A+ + +A +VT + V+ L +E +
Sbjct: 1064 MAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQ 1123
Query: 559 QSSMFI-INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQ 617
+ + + I++ K QL L + E E E +L+ + + LQ
Sbjct: 1124 KGELNVQISERKTQLT------LIKQEIEKEEENLQVVLRQMSKHKT---ELKNILDMLQ 1174
Query: 618 RASAKKDEILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
+ E+ +K +++++ L+ T++ LE+++ +++ L + ++ + +
Sbjct: 1175 ---LENHELQGLKLQHDQRVSELEKTQVAVLEEKL-----ELENLQQISQQQKGEIEWQK 1226
Query: 677 QKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEM--TLDVATAKQVDFK 733
Q + K+ M R +Q ++ ++K+ E ++E+C + ++ T V A + + K
Sbjct: 1227 QLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSK 1286
Query: 734 QKISTLRN---RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV----QDIVNLEE 786
+ S L V+ Q++L+ N+ +L+ + +++L ++ V +++ N+++
Sbjct: 1287 MEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD 1346
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ D T L+ + E + E ++ + + + + E+
Sbjct: 1347 HLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN-RFEDCQKEEETKQQ-QLQVLQNEI 1404
Query: 847 AFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
NK+K + E+ Q +K E K++ + L E+Q Q+ + K+D + ++
Sbjct: 1405 EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1464
Query: 906 AKQEVYKRDL--DDNLC------LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
E R L ++ C L + + ++ ++Q E + +L + KE + +
Sbjct: 1465 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 1524
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK--MYELHVTKAIDK 1015
+ + + ++ + ++ LK++LK R++LEK+L +E+K E+ + + +
Sbjct: 1525 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNL---LEQKQENSCIQKEMATIELVAQ 1581
Query: 1016 DIREYAVALDKCLMEFHREKME 1037
D E A L K L + E E
Sbjct: 1582 DNHERARRLMKELNQMQYEYTE 1603
Score = 38.7 bits (86), Expect = 0.12
Identities = 72/376 (19%), Positives = 150/376 (39%), Gaps = 27/376 (7%)
Query: 605 VPGKLEKVTEDLQRASAKK--DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+ G +E + +L+ + K ++I+ EK + +E+ + ++ + + ++++
Sbjct: 862 IDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTK 921
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E + + ++ + Q D L+R QE T +A D ++
Sbjct: 922 EKTKNAVEKFTDAKRSLL---QTESDAEELERRAQE--TAVNLVKA--------DQQLRS 968
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ--- 779
A AK ++ + KI +K K + A + Q L +KK K EEL QK ++
Sbjct: 969 LQADAKDLE-QHKIKQ-EEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 1026
Query: 780 -----DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLI 834
+ L+ES+ LQ+ + V ++ K E+ ++
Sbjct: 1027 RNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMV 1086
Query: 835 EAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVL 894
+A + + + +V I++ K +K E N ++ E++ Q+ +Q +
Sbjct: 1087 QAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK-GELNVQISERKTQLTLIKQEI 1145
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEK 953
K+ + L+ + + +K +L + L L+ ++ + Q D+ +L L EK
Sbjct: 1146 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1205
Query: 954 ESLIIKQTKLFQQKAE 969
L Q QQK E
Sbjct: 1206 LELENLQQISQQQKGE 1221
>AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein.
Length = 2325
Score = 59.3 bits (137), Expect = 8e-08
Identities = 148/825 (17%), Positives = 310/825 (37%), Gaps = 48/825 (5%)
Query: 192 DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
+ L++ ++ A NL + +++A K+LE K KE KI K S+
Sbjct: 1478 EELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSD----- 1532
Query: 252 KFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHK 311
F L S+ +EK+ + +++ + ++AE +Q +E+E + ++E LKS
Sbjct: 1533 -FQCL-SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVT 1590
Query: 312 VQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXX 371
Q+ + +++ +E H N
Sbjct: 1591 SQQQEMAVLDRQLGHKKEEL---HLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKS 1647
Query: 372 XXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQK 426
+ Q +E + + +QEI ++E+ + Q + EL + LQ
Sbjct: 1648 LLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQL 1707
Query: 427 QTAKLKE-KEMIEENLKTKEK-QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRN 484
+ +L+ K ++ + EK Q+ VL+ K + ++ + + + E + R
Sbjct: 1708 ENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKR- 1766
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ L E++ ++E + +L A+ K A + + S
Sbjct: 1767 EIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKL--AQTKRVLAAAEENSKMEQS-- 1822
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
+EKL+ LQ + +N+ K L ++ + + E N
Sbjct: 1823 --NLEKLELNVRKLQQELDQLNRDKLSLHND-----ISAMQQQLQEKREAVNSLQEELAN 1875
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
V L +DL + +D +LS ++ +K + +K Q++ L
Sbjct: 1876 VQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNE 1935
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV 724
+EE + L++ E ++ +R +E K T K +KEQ ++ E+T
Sbjct: 1936 IEENKLKLVQQEMMFQRLQK--------ERESEESKLETSKV-TLKEQQHQLEKELTDQK 1986
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ QV K+ RV+T Q++ +TL + K + E +K +++ L
Sbjct: 1987 SKLDQV--LSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLAL 2044
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
++ +++D +LKE ++ + + +N + ++ I K
Sbjct: 2045 QKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQK- 2103
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
E+A ++ + D + + +M+ K M QK + + ++ + TLK E
Sbjct: 2104 EMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSE 2163
Query: 905 IAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE---ELNE---KESLII 958
+ K E+ + N L + D+ ++++ L +L + + +NE +E L
Sbjct: 2164 V-KDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNF 2222
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
Q + + +L+ + +L +SK E + K
Sbjct: 2223 SQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGK 2267
Score = 57.6 bits (133), Expect = 3e-07
Identities = 125/682 (18%), Positives = 291/682 (42%), Gaps = 64/682 (9%)
Query: 388 ENELNIEECQQEINE---DEKAVEQYEQEMDELSQKITKL--QKQT---AKLKEKEMIEE 439
E +N+ + Q++ D K +EQ++ + +E+ ++I K+ K + K+KE + E
Sbjct: 1486 ETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTE 1545
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
L+ +K + + + L L K+ V + R E+
Sbjct: 1546 ELQKLQKDIEMAERNEDHHLQVL------KESEVLLQA----KRAELEKLKSQVTSQQQE 1595
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS-KYTTTVEKLQDEQNVL 558
L+ + H +E L+ + + +A+ + +A +VT + V+ L +E +
Sbjct: 1596 MAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQ 1655
Query: 559 QSSMFI-INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQ 617
+ + + I++ K QL L + E E E +L+ + + LQ
Sbjct: 1656 KGELNVQISERKTQLT------LIKQEIEKEEENLQVVLRQMSKHKT---ELKNILDMLQ 1706
Query: 618 RASAKKDEILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
+ E+ +K +++++ L+ T++ LE+++ +++ L + ++ + +
Sbjct: 1707 ---LENHELQGLKLQHDQRVSELEKTQVAVLEEKL-----ELENLQQISQQQKGEIEWQK 1758
Query: 677 QKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEM--TLDVATAKQVDFK 733
Q + K+ M R +Q ++ ++K+ E ++E+C + ++ T V A + + K
Sbjct: 1759 QLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSK 1818
Query: 734 QKISTLRN---RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV----QDIVNLEE 786
+ S L V+ Q++L+ N+ +L+ + +++L ++ V +++ N+++
Sbjct: 1819 MEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD 1878
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ D T L+ + E + E ++ + + + + E+
Sbjct: 1879 HLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN-RFEDCQKEEETKQQ-QLQVLQNEI 1936
Query: 847 AFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
NK+K + E+ Q +K E K++ + L E+Q Q+ + K+D + ++
Sbjct: 1937 EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 1996
Query: 906 AKQEVYKRDL--DDNLC------LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
E R L ++ C L + + ++ ++Q E + +L + KE + +
Sbjct: 1997 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 2056
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK--MYELHVTKAIDK 1015
+ + + ++ + ++ LK++LK R++LEK+L +E+K E+ + + +
Sbjct: 2057 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNL---LEQKQENSCIQKEMATIELVAQ 2113
Query: 1016 DIREYAVALDKCLMEFHREKME 1037
D E A L K L + E E
Sbjct: 2114 DNHERARRLMKELNQMQYEYTE 2135
Score = 50.0 bits (114), Expect = 5e-05
Identities = 80/394 (20%), Positives = 181/394 (45%), Gaps = 33/394 (8%)
Query: 616 LQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
+Q + DE L +N + T DT++ EK+I T++ L++ +E+ ++
Sbjct: 411 VQIKKMEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRA 470
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK 735
++ KQ+ + L + + K + K + + Q + + LD+ + KQ+
Sbjct: 471 TEEF---KQLE-EAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQ-KQE 525
Query: 736 ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDC 795
I+ + +K Q +++ L + K + K + ++++ DI+N + +QL+S
Sbjct: 526 IAGKQKEIKDLQIAIDS----LDSKDPKHSHMKAQKSGKEQQL-DIMN--KQYQQLESRL 578
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG-SAYIAKVEVAFNKVKSL 854
I LE L E A E ++++ + + +G Y+ ++ + ++
Sbjct: 579 DEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNE 638
Query: 855 DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRD 914
+++ K+ + R + ++++ D+L + + D + + K++ L+ + +Q
Sbjct: 639 CRKLRDEKETLLQR-LTEVEQERDQL----EIVAMDAENMRKELAELESALQEQH----- 688
Query: 915 LDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGAL 974
+ N L++ Q D++ ++ EL +LN + E N+ + + K T+L Q E +
Sbjct: 689 -EVNASLQQTQGDLSAYEA---ELEARLN-LRDAEANQLKEELEKVTRLTQ--LEQSALQ 741
Query: 975 SELKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
+EL+K + +N L K ++ E+K +E ELH
Sbjct: 742 AELEKERQALKNALGK--AQFSEEKEQENS-ELH 772
Score = 38.7 bits (86), Expect = 0.12
Identities = 72/376 (19%), Positives = 150/376 (39%), Gaps = 27/376 (7%)
Query: 605 VPGKLEKVTEDLQRASAKK--DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+ G +E + +L+ + K ++I+ EK + +E+ + ++ + + ++++
Sbjct: 1394 IDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTK 1453
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E + + ++ + Q D L+R QE T +A D ++
Sbjct: 1454 EKTKNAVEKFTDAKRSLL---QTESDAEELERRAQE--TAVNLVKA--------DQQLRS 1500
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ--- 779
A AK ++ + KI +K K + A + Q L +KK K EEL QK ++
Sbjct: 1501 LQADAKDLE-QHKIKQ-EEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 1558
Query: 780 -----DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLI 834
+ L+ES+ LQ+ + V ++ K E+ ++
Sbjct: 1559 RNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMV 1618
Query: 835 EAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVL 894
+A + + + +V I++ K +K E N ++ E++ Q+ +Q +
Sbjct: 1619 QAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK-GELNVQISERKTQLTLIKQEI 1677
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEK 953
K+ + L+ + + +K +L + L L+ ++ + Q D+ +L L EK
Sbjct: 1678 EKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1737
Query: 954 ESLIIKQTKLFQQKAE 969
L Q QQK E
Sbjct: 1738 LELENLQQISQQQKGE 1753
Score = 37.1 bits (82), Expect = 0.38
Identities = 37/161 (22%), Positives = 80/161 (49%), Gaps = 12/161 (7%)
Query: 172 KKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKL-LENYATTVKAKQKELEDSYKKNT 230
KK+ E ++ + S L + K+R++ A +L+L +E + KQKE++D
Sbjct: 484 KKISEAGKDLL-YKQLSGRLQLVNKLRQE-ALDLELQMEKQKQEIAGKQKEIKDLQIAID 541
Query: 231 SFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIV-----ETAKIAEI-ENIT 284
S + ++ K ++ K+ + + ++ Q Q+ ++ R ++I+ ET +I ++ E +T
Sbjct: 542 SLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQ-LESRLDEILSRIAKETEEIKDLEEQLT 600
Query: 285 E--VQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKK 323
E + NE + + ++ ++ K Q +QA E +K
Sbjct: 601 EGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRK 641
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 58.8 bits (136), Expect = 1e-07
Identities = 159/861 (18%), Positives = 340/861 (39%), Gaps = 84/861 (9%)
Query: 188 SDCLDRLKKIRKDYAQNL-KLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S ++L+ R D+ + + L E++ + QKE++ Y +KE E + ++
Sbjct: 542 SSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHA 601
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E + I L E ++Q +E K++ + + +T E AE KT +EK+ L
Sbjct: 602 NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL-GTETAEFAE--LKTQIEKMR-L 657
Query: 307 KSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQS 366
H+++ Q ++ + R+ H + + A +S
Sbjct: 658 DYQHEIENLQNQQDSE---------RAAHAK----EMEALRAKLMKVIKEKENSLEAIRS 704
Query: 367 XXXXXXXXXXXXXXXXXHKQAENELNIEE---CQQEINEDEKAVEQYEQEMDELSQK--- 420
+K E E+ ++E Q + NE K ++ + ++ +K
Sbjct: 705 KLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLD 764
Query: 421 ITKLQKQTAKLK-EKEMIEENLKTKEKQ---LIVLKNKHKTALMELLGNVPEKDFAVT-I 475
+ L+K +++ K E + + + L+ EKQ L + KN + + + ++ +T +
Sbjct: 765 LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNL 824
Query: 476 NKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKAC--- 532
+ EV E ++ S+ E ++L + E++
Sbjct: 825 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 884
Query: 533 -----GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKG----QL-KDNSCCPLCN 582
+ + E+L + L++ + I K G QL K N L
Sbjct: 885 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE 944
Query: 583 RGFEN-ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLK- 640
R E + + ++ K + Q A+ K +E K L K++ L+
Sbjct: 945 RDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE--EKKELERKLSDLEK 1002
Query: 641 -----DTEIPQLEKRIVDVDTQIKTLNETV-EEITMSLIEPEQKMTTAKQIHGDMPMLDR 694
+ +L+ R ++ KT +E + + + +L++ E K+ A++ + +
Sbjct: 1003 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGL----- 1057
Query: 695 YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+QE++ + K+ + K D+ ++ T K+K TL + T Q N
Sbjct: 1058 -LQELEELRKQADKAKAAQTAEDAMQIMEQMT------KEKTETLASLEDTKQTNAKLQN 1110
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDIVN--LEESKKQLQSDCXXXXXXXXXXXXAITPL 812
+L TL E K EE LN K++ + N +EE +K++++ A+
Sbjct: 1111 -ELDTLKENNLKNVEE-LNKSKELLTVENQKMEEFRKEIET-LKQAAAQKSQQLSALQEE 1167
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSA---YIAKVEVAFNK-VKSLDAEIQQHKKKNVPR 868
V L E++ + V ++ L E S + +++ +K +K D E + +K++
Sbjct: 1168 NVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEE-KASLQKSISI 1226
Query: 869 EMEKIQEANDKLMEKQKQIMTDR------QVLTKKIDTLKDEIAKQEVYKRDLDDNLCLR 922
+ E + +L + + ++ R + L + TL+ + K E+ ++L+ L L+
Sbjct: 1227 TSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLE--LQLK 1284
Query: 923 KAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
+ + +++ D ++ + +++ S+I+ + Q +SE +L
Sbjct: 1285 ENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSE--AALN 1342
Query: 983 GFRNELEKSLSKDIEKKFREK 1003
G ++L S D EK+ ++K
Sbjct: 1343 GNGDDLNNYDSDDQEKQSKKK 1363
Score = 58.4 bits (135), Expect = 1e-07
Identities = 162/842 (19%), Positives = 335/842 (39%), Gaps = 75/842 (8%)
Query: 81 QVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKD-VSSRCADLD 139
Q KL++ D Q E+T S+K A+++T + + + + ++ K + + S+ +
Sbjct: 545 QEKLEVTRT-DHQREIT-SLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHAN 602
Query: 140 ILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRK 199
+ + + K+ L + + HQ+ E KV + ++++ +++K+R
Sbjct: 603 KENSDVIALWKSKLETAIASHQQAM-----EELKVSFSKGLGTETAEFAELKTQIEKMRL 657
Query: 200 DYAQNLKLLENYATTVKAKQ-KELEDSYKKNTSFNKEEEKI--ANEKSSNEIEYNKFILL 256
DY ++ L+N + +A KE+E K KE+E A ++ E + +
Sbjct: 658 DYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEM 717
Query: 257 E---SQNQEKIDKRNEQIVETAKIAE----IENITEVQTNEEAENATKTILEKVESL-KS 308
E ++ QE K E V AK E I+N T E + L K S KS
Sbjct: 718 EDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKS 777
Query: 309 DHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXX 368
+ K + Q + EK+ + E ++ + +++ +Q
Sbjct: 778 EMKKLRQQLEAAEKQIKHLEIE-KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 836
Query: 369 XXXXXXXXXXXXXXXHKQAENELNIEECQQE-INEDEKAVEQYEQEMDELSQKITKLQKQ 427
+ +E ++++ QE +N+ + EQ+ +L + L
Sbjct: 837 TLEKELQILKEKFA--EASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADM 894
Query: 428 TAKLKEKEMIEENL-KTKEK------QLIVLKNKHKTALMELLGNVPEKDFAVTINKFEC 480
AK +EK+ EE L K KEK +++ + + + L ++ + K+ V + +
Sbjct: 895 EAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKL 954
Query: 481 EVRNE---VXXXXXXXXXXXXXXXXLEAERKHIRE--SLNERRSELTKAEDKIYKACGTQ 535
NE EA +KH E L + S+L K + + C Q
Sbjct: 955 TKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQC--Q 1012
Query: 536 PYDVTLSKYTTTVEKLQDE--QNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXX 593
+ T+ + +E QN+ ++ + +K KG ++NS +++
Sbjct: 1013 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAK 1072
Query: 594 XXXXXXXXXMNVPGKLEKVT------EDLQRASAK-KDEILSMKSLN----EKITTLKD- 641
+ ++ T ED ++ +AK ++E+ ++K N E++ K+
Sbjct: 1073 AAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKEL 1132
Query: 642 ------------TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
EI L++ Q+ L E ++ L ++T+ +++ +
Sbjct: 1133 LTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER 1192
Query: 690 PMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLRNRVKTTQK 748
+L+ + E+K KF +K+ + S + ++ + +A + ++ LRN V T +
Sbjct: 1193 SVLNNQLLEMKKRESKF--IKDADEEKASLQKSISITSALLTEKDAELEKLRNEV-TVLR 1249
Query: 749 KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXX 807
NA K L ++ + K +L + KV+++ + L+E+K+QL S
Sbjct: 1250 GENASAKSLHSVVQTLESDKVKL---ELKVKNLELQLKENKRQLSSSSGNTDTQADEDER 1306
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDL-IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNV 866
A L I ++ R+N+DL ++ A + + + + D++ Q+ + K
Sbjct: 1307 AQESQIDFLNSVI---VDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKK 1363
Query: 867 PR 868
PR
Sbjct: 1364 PR 1365
Score = 57.6 bits (133), Expect = 3e-07
Identities = 116/606 (19%), Positives = 237/606 (39%), Gaps = 47/606 (7%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
E I+ + E N + +E+ K+T LQ+ L E ++E L EK+L
Sbjct: 790 EKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN---LSEVSQVKETL---EKELQ 843
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+LK K A E + ++ T+NK + + +EA+
Sbjct: 844 ILKEKFAEASEEAVS--VQRSMQETVNKLH-QKEEQFNMLSSDLEKLRENLADMEAK--- 897
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
RE +ER +L KA++K+ ++ + K+ DE + + + +
Sbjct: 898 FREK-DEREEQLIKAKEKLENDIAE--IMKMSGDNSSQLTKMNDELRLKERDVEELQLKL 954
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK-LEKVTEDLQRA-SAKKDEIL 627
+ +N+ + E+ + K LE+ DL++ ++
Sbjct: 955 TKANENAS--FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 1012
Query: 628 SMKSLNEKITT---LKDTEIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK 683
+K+ E+ T+ K EI Q L+K ++D + ++K E + L E ++ AK
Sbjct: 1013 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAK 1072
Query: 684 --QIHGD-MPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM-TLDVATAKQVDF------- 732
Q D M ++++ +E E K+ + +E+ TL K V+
Sbjct: 1073 AAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKEL 1132
Query: 733 ----KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESK 788
QK+ R ++T ++ +++L L E+ K EEL ++ +V LEE +
Sbjct: 1133 LTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER 1192
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
L + + +L++ I + ++ +E + +
Sbjct: 1193 SVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGEN 1252
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
KSL + +Q + V E+ K++ +L E ++Q+ + + DT DE +
Sbjct: 1253 ASAKSLHSVVQTLESDKVKLEL-KVKNLELQLKENKRQLSSS----SGNTDTQADEDERA 1307
Query: 909 EVYKRDLDDNLC--LRKAQTDITNWQKQDDE--LNEKLNGINKEELNEKESLIIKQTKLF 964
+ + D +++ L++ D+ + E LN + +N + +++E K+ +LF
Sbjct: 1308 QESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLF 1367
Query: 965 QQKAEC 970
+C
Sbjct: 1368 CDICDC 1373
Score = 48.0 bits (109), Expect = 2e-04
Identities = 93/423 (21%), Positives = 188/423 (44%), Gaps = 56/423 (13%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
++ EDLQ ++E ++ L E T L+ I +LE+ ++ T+ L +E+
Sbjct: 435 KRKVEDLQ--FRVEEESITKGDL-ETQTKLEHARIKELEQSLLFEKTKADKLQRELEDTR 491
Query: 670 MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL--DVATA 727
++ + + ++ ++ D+ + +QE+ + ++ E+ K GDVD ++L ++++
Sbjct: 492 VATVSEKSRIM---ELEKDLALR---VQEVAELRRRLESNKP-AGDVDMSLSLLQEISSL 544
Query: 728 KQ------VDFKQKISTLRN----RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
++ D +++I++L+ R +T QK++ A + L ++ K +L + K+
Sbjct: 545 QEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKE 604
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITP-LEVALKEKIEAKTEVVRRNRDLIEA 836
D++ L +SK L++ + + L E E KT++ + D
Sbjct: 605 NSDVIALWKSK--LETAIASHQQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLD---- 658
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
Y ++E N D+E H K EME ++ KLM+ K+ + +
Sbjct: 659 ---YQHEIE---NLQNQQDSERAAHAK-----EMEALRA---KLMKVIKEKENSLEAIRS 704
Query: 897 KIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
K+D +D+ + +++D L L++A+ + K+ + L K N K N
Sbjct: 705 KLDKAEDQ------HLVEMEDTLNKLQEAEIKV----KELEVLQAKCNEQTKVIDNFTSQ 754
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L + KL A A SE K +K R +LE + K I+ EK E +I +
Sbjct: 755 LKATEEKLLDLDA-LRKASSEGKSEMKKLRQQLE-AAEKQIKHLEIEKNAESSKASSITR 812
Query: 1016 DIR 1018
+++
Sbjct: 813 ELQ 815
Score = 41.9 bits (94), Expect = 0.013
Identities = 80/472 (16%), Positives = 184/472 (38%), Gaps = 34/472 (7%)
Query: 64 ECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVD 123
E V AK N T+V+ ++ ++K L++ K A ++ K++ + L L +
Sbjct: 733 ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRK--ASSEGKSEMKKLRQQLEAAE 790
Query: 124 ESGKTKDV--SSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEI 181
+ K ++ ++ + + E G + N QE+ L E +VKE ++
Sbjct: 791 KQIKHLEIEKNAESSKASSITRELQGRELKLTNL-----QEN----LSEVSQVKETLEKE 841
Query: 182 FDA--DKYSDCLDRLKKIRKDYAQNLKLLEN-------YATTVKAKQKELEDSYKKNTSF 232
+K+++ + +++ + + L ++ ++ ++ L D K
Sbjct: 842 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREK 901
Query: 233 NKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEA 292
++ EE++ K E + + + + N ++ K N+++ + E + + NE A
Sbjct: 902 DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENA 961
Query: 293 ENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXX 352
K+I + ++K++ Q++ EE+K + ++ S +
Sbjct: 962 SFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKE--LERKLSDLEKKMETSHNQCQELKAR 1017
Query: 353 XXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA-VEQYE 411
+ + ++ + EN ++E ++ + +KA Q
Sbjct: 1018 YERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTA 1077
Query: 412 QEMDELSQKITKLQKQT-AKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKD 470
++ ++ +++TK + +T A L++ + L + +L LK + + EL N ++
Sbjct: 1078 EDAMQIMEQMTKEKTETLASLEDTKQTNAKL---QNELDTLKENNLKNVEEL--NKSKEL 1132
Query: 471 FAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V K E E R E+ L+ E + E L R E+T
Sbjct: 1133 LTVENQKME-EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVT 1183
Score = 41.1 bits (92), Expect = 0.023
Identities = 81/417 (19%), Positives = 173/417 (41%), Gaps = 37/417 (8%)
Query: 618 RASAKKDEILSMKSLNEKITTLKDTEIPQLE---KRIVDVDTQIKTLNETVEEITMSLIE 674
R + EI ++ + EK++ ++ +LE K DV K+ ET +E
Sbjct: 569 REETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAME 628
Query: 675 PEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFE-AVKEQCGDVDSEMTLDVATAKQVDFK 733
E K++ +K + + +I+ + ++ ++ DSE A AK+++
Sbjct: 629 -ELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERA---AHAKEMEAL 684
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLN----TQKKVQDIVNLEESKK 789
+ + L +K + L A KL ++ E+ LN + KV+++ L+
Sbjct: 685 R--AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCN 742
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
+ + L+ K E K+E+ ++ R +EA I +E+ N
Sbjct: 743 EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEM-KKLRQQLEAAEKQIKHLEIEKN 801
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQE 909
S K ++ RE++ + L E ++ ++ L K++ LK++ A+
Sbjct: 802 AESS--------KASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEAS 853
Query: 910 VYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
++ + ++++ + N Q + E+ N ++ + +E+L + K F++K E
Sbjct: 854 ------EEAVSVQRSMQETVNKLHQKE---EQFNMLSSDLEKLRENLADMEAK-FREKDE 903
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
L + K+ L+ E+ K +S D + + EL + ++D+ E + L K
Sbjct: 904 REEQLIKAKEKLENDIAEIMK-MSGDNSSQLTKMNDELRLK---ERDVEELQLKLTK 956
Score = 32.7 bits (71), Expect = 8.2
Identities = 52/268 (19%), Positives = 112/268 (41%), Gaps = 17/268 (6%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK-VTALAKKKTKFQTLDSFLSTVDESG 126
H+ + + L + K+ A+++ + + ++ + A K QT + + +++
Sbjct: 1029 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQM- 1087
Query: 127 KTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFD-EIFDAD 185
TK+ + A L E+ + A L + + +E++ ++E K KE E +
Sbjct: 1088 -TKEKTETLASL-----EDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKME 1141
Query: 186 KYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
++ ++ LK+ +Q L L+ + + D + +E + N+
Sbjct: 1142 EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLE 1201
Query: 246 NEIEYNKFILLESQNQEKIDKRNE--QIVETAKIAEIENITEVQTNEEAENAT-KTILEK 302
+ +KFI + + + K + T K AE+E + T ENA+ K++
Sbjct: 1202 MKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1261
Query: 303 VESLKSDH-----KVQKSQADEEEKKAQ 325
V++L+SD KV+ + +E K Q
Sbjct: 1262 VQTLESDKVKLELKVKNLELQLKENKRQ 1289
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 58.8 bits (136), Expect = 1e-07
Identities = 159/861 (18%), Positives = 340/861 (39%), Gaps = 84/861 (9%)
Query: 188 SDCLDRLKKIRKDYAQNL-KLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
S ++L+ R D+ + + L E++ + QKE++ Y +KE E + ++
Sbjct: 553 SSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHA 612
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E + I L E ++Q +E K++ + + +T E AE KT +EK+ L
Sbjct: 613 NKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL-GTETAEFAE--LKTQIEKMR-L 668
Query: 307 KSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQS 366
H+++ Q ++ + R+ H + + A +S
Sbjct: 669 DYQHEIENLQNQQDSE---------RAAHAK----EMEALRAKLMKVIKEKENSLEAIRS 715
Query: 367 XXXXXXXXXXXXXXXXXHKQAENELNIEE---CQQEINEDEKAVEQYEQEMDELSQK--- 420
+K E E+ ++E Q + NE K ++ + ++ +K
Sbjct: 716 KLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLD 775
Query: 421 ITKLQKQTAKLK-EKEMIEENLKTKEKQ---LIVLKNKHKTALMELLGNVPEKDFAVT-I 475
+ L+K +++ K E + + + L+ EKQ L + KN + + + ++ +T +
Sbjct: 776 LDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQGRELKLTNL 835
Query: 476 NKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKAC--- 532
+ EV E ++ S+ E ++L + E++
Sbjct: 836 QENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 895
Query: 533 -----GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKG----QL-KDNSCCPLCN 582
+ + E+L + L++ + I K G QL K N L
Sbjct: 896 EKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE 955
Query: 583 RGFEN-ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLK- 640
R E + + ++ K + Q A+ K +E K L K++ L+
Sbjct: 956 RDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE--EKKELERKLSDLEK 1013
Query: 641 -----DTEIPQLEKRIVDVDTQIKTLNETV-EEITMSLIEPEQKMTTAKQIHGDMPMLDR 694
+ +L+ R ++ KT +E + + + +L++ E K+ A++ + +
Sbjct: 1014 KMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGL----- 1068
Query: 695 YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+QE++ + K+ + K D+ ++ T K+K TL + T Q N
Sbjct: 1069 -LQELEELRKQADKAKAAQTAEDAMQIMEQMT------KEKTETLASLEDTKQTNAKLQN 1121
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQDIVN--LEESKKQLQSDCXXXXXXXXXXXXAITPL 812
+L TL E K EE LN K++ + N +EE +K++++ A+
Sbjct: 1122 -ELDTLKENNLKNVEE-LNKSKELLTVENQKMEEFRKEIET-LKQAAAQKSQQLSALQEE 1178
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSA---YIAKVEVAFNK-VKSLDAEIQQHKKKNVPR 868
V L E++ + V ++ L E S + +++ +K +K D E + +K++
Sbjct: 1179 NVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEE-KASLQKSISI 1237
Query: 869 EMEKIQEANDKLMEKQKQIMTDR------QVLTKKIDTLKDEIAKQEVYKRDLDDNLCLR 922
+ E + +L + + ++ R + L + TL+ + K E+ ++L+ L L+
Sbjct: 1238 TSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLE--LQLK 1295
Query: 923 KAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
+ + +++ D ++ + +++ S+I+ + Q +SE +L
Sbjct: 1296 ENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSE--AALN 1353
Query: 983 GFRNELEKSLSKDIEKKFREK 1003
G ++L S D EK+ ++K
Sbjct: 1354 GNGDDLNNYDSDDQEKQSKKK 1374
Score = 58.4 bits (135), Expect = 1e-07
Identities = 162/842 (19%), Positives = 335/842 (39%), Gaps = 75/842 (8%)
Query: 81 QVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKD-VSSRCADLD 139
Q KL++ D Q E+T S+K A+++T + + + + ++ K + + S+ +
Sbjct: 556 QEKLEVTRT-DHQREIT-SLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHAN 613
Query: 140 ILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRK 199
+ + + K+ L + + HQ+ E KV + ++++ +++K+R
Sbjct: 614 KENSDVIALWKSKLETAIASHQQAM-----EELKVSFSKGLGTETAEFAELKTQIEKMRL 668
Query: 200 DYAQNLKLLENYATTVKAKQ-KELEDSYKKNTSFNKEEEKI--ANEKSSNEIEYNKFILL 256
DY ++ L+N + +A KE+E K KE+E A ++ E + +
Sbjct: 669 DYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEM 728
Query: 257 E---SQNQEKIDKRNEQIVETAKIAE----IENITEVQTNEEAENATKTILEKVESL-KS 308
E ++ QE K E V AK E I+N T E + L K S KS
Sbjct: 729 EDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKS 788
Query: 309 DHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXX 368
+ K + Q + EK+ + E ++ + +++ +Q
Sbjct: 789 EMKKLRQQLEAAEKQIKHLEIE-KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKE 847
Query: 369 XXXXXXXXXXXXXXXHKQAENELNIEECQQE-INEDEKAVEQYEQEMDELSQKITKLQKQ 427
+ +E ++++ QE +N+ + EQ+ +L + L
Sbjct: 848 TLEKELQILKEKFA--EASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADM 905
Query: 428 TAKLKEKEMIEENL-KTKEK------QLIVLKNKHKTALMELLGNVPEKDFAVTINKFEC 480
AK +EK+ EE L K KEK +++ + + + L ++ + K+ V + +
Sbjct: 906 EAKFREKDEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKL 965
Query: 481 EVRNE---VXXXXXXXXXXXXXXXXLEAERKHIRE--SLNERRSELTKAEDKIYKACGTQ 535
NE EA +KH E L + S+L K + + C Q
Sbjct: 966 TKANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQC--Q 1023
Query: 536 PYDVTLSKYTTTVEKLQDE--QNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXX 593
+ T+ + +E QN+ ++ + +K KG ++NS +++
Sbjct: 1024 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAK 1083
Query: 594 XXXXXXXXXMNVPGKLEKVT------EDLQRASAK-KDEILSMKSLN----EKITTLKD- 641
+ ++ T ED ++ +AK ++E+ ++K N E++ K+
Sbjct: 1084 AAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKEL 1143
Query: 642 ------------TEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
EI L++ Q+ L E ++ L ++T+ +++ +
Sbjct: 1144 LTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER 1203
Query: 690 PMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLRNRVKTTQK 748
+L+ + E+K KF +K+ + S + ++ + +A + ++ LRN V T +
Sbjct: 1204 SVLNNQLLEMKKRESKF--IKDADEEKASLQKSISITSALLTEKDAELEKLRNEV-TVLR 1260
Query: 749 KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXXXXXXXXXXXX 807
NA K L ++ + K +L + KV+++ + L+E+K+QL S
Sbjct: 1261 GENASAKSLHSVVQTLESDKVKL---ELKVKNLELQLKENKRQLSSSSGNTDTQADEDER 1317
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDL-IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNV 866
A L I ++ R+N+DL ++ A + + + + D++ Q+ + K
Sbjct: 1318 AQESQIDFLNSVI---VDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKK 1374
Query: 867 PR 868
PR
Sbjct: 1375 PR 1376
Score = 57.6 bits (133), Expect = 3e-07
Identities = 116/606 (19%), Positives = 237/606 (39%), Gaps = 47/606 (7%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
E I+ + E N + +E+ K+T LQ+ L E ++E L EK+L
Sbjct: 801 EKQIKHLEIEKNAESSKASSITRELQGRELKLTNLQEN---LSEVSQVKETL---EKELQ 854
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+LK K A E + ++ T+NK + + +EA+
Sbjct: 855 ILKEKFAEASEEAVS--VQRSMQETVNKLH-QKEEQFNMLSSDLEKLRENLADMEAK--- 908
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
RE +ER +L KA++K+ ++ + K+ DE + + + +
Sbjct: 909 FREK-DEREEQLIKAKEKLENDIAE--IMKMSGDNSSQLTKMNDELRLKERDVEELQLKL 965
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK-LEKVTEDLQRA-SAKKDEIL 627
+ +N+ + E+ + K LE+ DL++ ++
Sbjct: 966 TKANENAS--FLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQ 1023
Query: 628 SMKSLNEKITT---LKDTEIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK 683
+K+ E+ T+ K EI Q L+K ++D + ++K E + L E ++ AK
Sbjct: 1024 ELKARYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAK 1083
Query: 684 --QIHGD-MPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM-TLDVATAKQVDF------- 732
Q D M ++++ +E E K+ + +E+ TL K V+
Sbjct: 1084 AAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKEL 1143
Query: 733 ----KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESK 788
QK+ R ++T ++ +++L L E+ K EEL ++ +V LEE +
Sbjct: 1144 LTVENQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEER 1203
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
L + + +L++ I + ++ +E + +
Sbjct: 1204 SVLNNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGEN 1263
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
KSL + +Q + V E+ K++ +L E ++Q+ + + DT DE +
Sbjct: 1264 ASAKSLHSVVQTLESDKVKLEL-KVKNLELQLKENKRQLSSS----SGNTDTQADEDERA 1318
Query: 909 EVYKRDLDDNLC--LRKAQTDITNWQKQDDE--LNEKLNGINKEELNEKESLIIKQTKLF 964
+ + D +++ L++ D+ + E LN + +N + +++E K+ +LF
Sbjct: 1319 QESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLF 1378
Query: 965 QQKAEC 970
+C
Sbjct: 1379 CDICDC 1384
Score = 46.8 bits (106), Expect = 5e-04
Identities = 86/396 (21%), Positives = 175/396 (44%), Gaps = 53/396 (13%)
Query: 637 TTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI 696
T L+ I +LE+ ++ T+ L +E+ ++ + + ++ ++ D+ + +
Sbjct: 470 TKLEHARIKELEQSLLFEKTKADKLQRELEDTRVATVSEKSRIM---ELEKDLALR---V 523
Query: 697 QEIKTVTKKFEAVKEQCGDVDSEMTL--DVATAKQ------VDFKQKISTLRN----RVK 744
QE+ + ++ E+ K GDVD ++L ++++ ++ D +++I++L+ R +
Sbjct: 524 QEVAELRRRLESNKP-AGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREE 582
Query: 745 TTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXX 804
T QK++ A + L ++ K +L + K+ D++ L +SK L++
Sbjct: 583 THQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSK--LETAIASHQQAMEE 640
Query: 805 XXXAITP-LEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK 863
+ + L E E KT++ + D Y ++E N D+E H K
Sbjct: 641 LKVSFSKGLGTETAEFAELKTQIEKMRLD-------YQHEIE---NLQNQQDSERAAHAK 690
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL-CLR 922
EME ++ KLM+ K+ + + K+D +D+ + +++D L L+
Sbjct: 691 -----EMEALRA---KLMKVIKEKENSLEAIRSKLDKAEDQ------HLVEMEDTLNKLQ 736
Query: 923 KAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
+A+ + K+ + L K N K N L + KL A A SE K +K
Sbjct: 737 EAEIKV----KELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDA-LRKASSEGKSEMK 791
Query: 983 GFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR 1018
R +LE + K I+ EK E +I ++++
Sbjct: 792 KLRQQLE-AAEKQIKHLEIEKNAESSKASSITRELQ 826
Score = 41.9 bits (94), Expect = 0.013
Identities = 80/472 (16%), Positives = 184/472 (38%), Gaps = 34/472 (7%)
Query: 64 ECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVD 123
E V AK N T+V+ ++ ++K L++ K A ++ K++ + L L +
Sbjct: 744 ELEVLQAKCNEQTKVIDNFTSQLKATEEKLLDLDALRK--ASSEGKSEMKKLRQQLEAAE 801
Query: 124 ESGKTKDV--SSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEI 181
+ K ++ ++ + + E G + N QE+ L E +VKE ++
Sbjct: 802 KQIKHLEIEKNAESSKASSITRELQGRELKLTNL-----QEN----LSEVSQVKETLEKE 852
Query: 182 FDA--DKYSDCLDRLKKIRKDYAQNLKLLEN-------YATTVKAKQKELEDSYKKNTSF 232
+K+++ + +++ + + L ++ ++ ++ L D K
Sbjct: 853 LQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREK 912
Query: 233 NKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEA 292
++ EE++ K E + + + + N ++ K N+++ + E + + NE A
Sbjct: 913 DEREEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENA 972
Query: 293 ENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXX 352
K+I + ++K++ Q++ EE+K + ++ S +
Sbjct: 973 SFLQKSIEDM--TVKAEQSQQEAAKKHEEEKKE--LERKLSDLEKKMETSHNQCQELKAR 1028
Query: 353 XXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA-VEQYE 411
+ + ++ + EN ++E ++ + +KA Q
Sbjct: 1029 YERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTA 1088
Query: 412 QEMDELSQKITKLQKQT-AKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKD 470
++ ++ +++TK + +T A L++ + L + +L LK + + EL N ++
Sbjct: 1089 EDAMQIMEQMTKEKTETLASLEDTKQTNAKL---QNELDTLKENNLKNVEEL--NKSKEL 1143
Query: 471 FAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V K E E R E+ L+ E + E L R E+T
Sbjct: 1144 LTVENQKME-EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVT 1194
Score = 41.1 bits (92), Expect = 0.023
Identities = 81/417 (19%), Positives = 173/417 (41%), Gaps = 37/417 (8%)
Query: 618 RASAKKDEILSMKSLNEKITTLKDTEIPQLE---KRIVDVDTQIKTLNETVEEITMSLIE 674
R + EI ++ + EK++ ++ +LE K DV K+ ET +E
Sbjct: 580 REETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAME 639
Query: 675 PEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFE-AVKEQCGDVDSEMTLDVATAKQVDFK 733
E K++ +K + + +I+ + ++ ++ DSE A AK+++
Sbjct: 640 -ELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERA---AHAKEMEAL 695
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLN----TQKKVQDIVNLEESKK 789
+ + L +K + L A KL ++ E+ LN + KV+++ L+
Sbjct: 696 R--AKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCN 753
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
+ + L+ K E K+E+ ++ R +EA I +E+ N
Sbjct: 754 EQTKVIDNFTSQLKATEEKLLDLDALRKASSEGKSEM-KKLRQQLEAAEKQIKHLEIEKN 812
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQE 909
S K ++ RE++ + L E ++ ++ L K++ LK++ A+
Sbjct: 813 AESS--------KASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEAS 864
Query: 910 VYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
++ + ++++ + N Q + E+ N ++ + +E+L + K F++K E
Sbjct: 865 ------EEAVSVQRSMQETVNKLHQKE---EQFNMLSSDLEKLRENLADMEAK-FREKDE 914
Query: 970 CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
L + K+ L+ E+ K +S D + + EL + ++D+ E + L K
Sbjct: 915 REEQLIKAKEKLENDIAEIMK-MSGDNSSQLTKMNDELRLK---ERDVEELQLKLTK 967
Score = 32.7 bits (71), Expect = 8.2
Identities = 52/268 (19%), Positives = 112/268 (41%), Gaps = 17/268 (6%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK-VTALAKKKTKFQTLDSFLSTVDESG 126
H+ + + L + K+ A+++ + + ++ + A K QT + + +++
Sbjct: 1040 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQM- 1098
Query: 127 KTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFD-EIFDAD 185
TK+ + A L E+ + A L + + +E++ ++E K KE E +
Sbjct: 1099 -TKEKTETLASL-----EDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKME 1152
Query: 186 KYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
++ ++ LK+ +Q L L+ + + D + +E + N+
Sbjct: 1153 EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLE 1212
Query: 246 NEIEYNKFILLESQNQEKIDKRNE--QIVETAKIAEIENITEVQTNEEAENAT-KTILEK 302
+ +KFI + + + K + T K AE+E + T ENA+ K++
Sbjct: 1213 MKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1272
Query: 303 VESLKSDH-----KVQKSQADEEEKKAQ 325
V++L+SD KV+ + +E K Q
Sbjct: 1273 VQTLESDKVKLELKVKNLELQLKENKRQ 1300
>BC125087-1|AAI25088.1| 568|Homo sapiens CCDC41 protein protein.
Length = 568
Score = 58.4 bits (135), Expect = 1e-07
Identities = 78/399 (19%), Positives = 168/399 (42%), Gaps = 24/399 (6%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIEENLKT 443
++ + EL + ++ +D K VEQ +E L QK+ L+ + A+LK EKE E ++
Sbjct: 155 EEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVEN 214
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
++ + + + + L ++ + + E E+++ +
Sbjct: 215 AQRIQVRQLAEMQATVRSL--EAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREI 272
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMF 563
++E + + E+T + K+ A + +K + ++ LQ + +L+++
Sbjct: 273 NTLSSKVKELKHSNKLEIT--DIKLETARAKSELERERNKIQSELDGLQSDNEILKAA-- 328
Query: 564 IINKYKGQL--KDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLE--KVTEDLQRA 619
+ +K L KD E + N LE KV D+ R
Sbjct: 329 -VEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQ 387
Query: 620 SAKK--DEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
S K +E L + E+IT + + +L+++IV ++ K NE ++ + +
Sbjct: 388 SEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNEN-SDLKQQISSLQ 446
Query: 677 QKMTTAKQIHGDM----PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDF 732
++T+ Q D+ ML ++ +K + F + E+ +++E TL+ KQ+ +
Sbjct: 447 IQVTSLAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEK-AQLEAEKTLE---EKQIQW 502
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL 771
++ L R+ ++K N +KLQ + K +++L
Sbjct: 503 LEEKHKLHERITDREEKYNQAKEKLQRAAIAQKKLEQDL 541
Score = 32.7 bits (71), Expect = 8.2
Identities = 70/397 (17%), Positives = 165/397 (41%), Gaps = 41/397 (10%)
Query: 640 KDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM--PMLDRY-- 695
K T+ +L+ + ++ ++ + +EE+ + ++ P++ QI ++ PM +R+
Sbjct: 44 KQTQQEKLQLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELETPMRERFRN 103
Query: 696 ----IQEIKTVTKK-----------FEAVKEQCGDV--DSEMTLDVATAKQVDFKQKIST 738
+++ + V K FE KE+ + + ++ + A+ + K++
Sbjct: 104 LDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEE--- 160
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEESKKQLQSDCXX 797
LRN++ L +K+++ L +K ++L + +V ++ E S+ Q+++
Sbjct: 161 LRNQLLNVD--LTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENAQRI 218
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA----KVEVAFNKVKS 853
+ LE A K+ + E + + + ++ K E N + S
Sbjct: 219 QVRQLAEMQATVRSLE-AEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSS 277
Query: 854 LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
E++ K + + A +L ++ +I ++ L + LK + +V
Sbjct: 278 KVKELKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLV 337
Query: 914 DLDDNLCLRKAQTDITNWQK----QDD--ELNEKLNGINKEELNEKESLIIKQTKLFQQK 967
+ D L + +QK QD+ EL +L + K ++ E + + +++K
Sbjct: 338 EKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKV-EHDVWRQSEKDQYEEK 396
Query: 968 AECTGALSEL-KKSLKGFRNELEKSLSKDIEKKFREK 1003
+ E+ +K L+ R +L++ + IE +EK
Sbjct: 397 LRASQMAEEITRKELQSVRLKLQQQI-VTIENAEKEK 432
>AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated protein
CEP110 protein.
Length = 994
Score = 58.4 bits (135), Expect = 1e-07
Identities = 148/825 (17%), Positives = 309/825 (37%), Gaps = 48/825 (5%)
Query: 192 DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
+ L++ ++ A NL + +++A K+LE K KE KI K S+
Sbjct: 147 EELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSD----- 201
Query: 252 KFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHK 311
F L S+ +EK+ + +++ + ++AE +Q +E+E + ++E LKS
Sbjct: 202 -FQCL-SKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVT 259
Query: 312 VQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXX 371
Q+ + +++ +E H N
Sbjct: 260 SQQQEMAVLDRQLGHKKEEL---HLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKS 316
Query: 372 XXXXXXXXXXXXHKQ-AENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQK 426
+ Q +E + + +QEI ++E+ + Q + EL + LQ
Sbjct: 317 LLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELQNILDMLQL 376
Query: 427 QTAKLKE-KEMIEENLKTKEK-QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRN 484
+ +L+ K ++ + EK Q+ VL+ K + ++ + + + E + R
Sbjct: 377 ENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKR- 435
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ L E++ ++E + +L A+ K A + + S
Sbjct: 436 EIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKL--AQTKRVLAAAEENSKMEQS-- 491
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
+EKL LQ + +N+ K L ++ + + E N
Sbjct: 492 --NLEKLDLNVRKLQQELDQLNRDKLSLHND-----ISAMQQQLQEKREAVNSLQEELAN 544
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
V L +DL + +D +LS ++ +K + +K Q++ L
Sbjct: 545 VQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNE 604
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDV 724
+EE + L++ E ++ +R +E K T K +KEQ ++ E+T
Sbjct: 605 IEENKLKLVQQEMMFQRLQK--------ERESEESKLETSKV-TLKEQQHQLEKELTDQK 655
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ QV K+ RV+T Q++ +TL + K + E +K +++ L
Sbjct: 656 SKLDQV--LSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLAL 713
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
++ +++D +LKE ++ + + +N + ++ I K
Sbjct: 714 QKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQK- 772
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
E+A ++ + D + + +M+ K M QK + + ++ + TLK E
Sbjct: 773 EMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSE 832
Query: 905 IAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE---ELNE---KESLII 958
+ K E+ + N L + D+ ++++ L +L + + +NE +E L
Sbjct: 833 V-KDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNF 891
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
Q + + +L+ + +L +SK E + K
Sbjct: 892 SQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGK 936
Score = 58.0 bits (134), Expect = 2e-07
Identities = 125/682 (18%), Positives = 291/682 (42%), Gaps = 64/682 (9%)
Query: 388 ENELNIEECQQEINE---DEKAVEQYEQEMDELSQKITKL--QKQT---AKLKEKEMIEE 439
E +N+ + Q++ D K +EQ++ + +E+ ++I K+ K + K+KE + E
Sbjct: 155 ETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTE 214
Query: 440 NLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXX 499
L+ +K + + + L L K+ V + R E+
Sbjct: 215 ELQKLQKDIEMAERNEDHHLQVL------KESEVLLQA----KRAELEKLKSQVTSQQQE 264
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLS-KYTTTVEKLQDEQNVL 558
L+ + H +E L+ + + +A+ + +A +VT + V+ L +E +
Sbjct: 265 MAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQ 324
Query: 559 QSSMFI-INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQ 617
+ + + I++ K QL L + E E E +L+ + + LQ
Sbjct: 325 KGELNVQISERKTQLT------LIKQEIEKEEENLQVVLRQMSKHKT---ELQNILDMLQ 375
Query: 618 RASAKKDEILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPE 676
+ E+ +K +++++ L+ T++ LE+++ +++ L + ++ + +
Sbjct: 376 ---LENHELQGLKLQHDQRVSELEKTQVAVLEEKL-----ELENLQQISQQQKGEIEWQK 427
Query: 677 QKMTTAKQIHGDMPMLDRYIQE-IKTVTKKFEAVKEQCGDVDSEM--TLDVATAKQVDFK 733
Q + K+ M R +Q ++ ++K+ E ++E+C + ++ T V A + + K
Sbjct: 428 QLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSK 487
Query: 734 QKISTLRN---RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV----QDIVNLEE 786
+ S L V+ Q++L+ N+ +L+ + +++L ++ V +++ N+++
Sbjct: 488 MEQSNLEKLDLNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQD 547
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ D T L+ + E + E ++ + + + + E+
Sbjct: 548 HLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWAN-RFEDCQKEEETKQQ-QLQVLQNEI 605
Query: 847 AFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
NK+K + E+ Q +K E K++ + L E+Q Q+ + K+D + ++
Sbjct: 606 EENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKV 665
Query: 906 AKQEVYKRDL--DDNLC------LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
E R L ++ C L + + ++ ++Q E + +L + KE + +
Sbjct: 666 LAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFS 725
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK--MYELHVTKAIDK 1015
+ + + ++ + ++ LK++LK R++LEK+L +E+K E+ + + +
Sbjct: 726 LLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNL---LEQKQENSCIQKEMATIELVAQ 782
Query: 1016 DIREYAVALDKCLMEFHREKME 1037
D E A L K L + E E
Sbjct: 783 DNHERARRLMKELNQMQYEYTE 804
Score = 39.1 bits (87), Expect = 0.094
Identities = 72/376 (19%), Positives = 150/376 (39%), Gaps = 27/376 (7%)
Query: 605 VPGKLEKVTEDLQRASAKK--DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+ G +E + +L+ + K ++I+ EK + +E+ + ++ + + ++++
Sbjct: 63 IDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTK 122
Query: 663 ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E + + ++ + Q D L+R QE T +A D ++
Sbjct: 123 EKTKNAVEKFTDAKRSLL---QTESDAEELERRAQE--TAVNLVKA--------DQQLRS 169
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ--- 779
A AK ++ + KI +K K + A + Q L +KK K EEL QK ++
Sbjct: 170 LQADAKDLE-QHKIKQ-EEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAE 227
Query: 780 -----DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLI 834
+ L+ES+ LQ+ + V ++ K E+ ++
Sbjct: 228 RNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMV 287
Query: 835 EAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVL 894
+A + + + +V I++ K +K E N ++ E++ Q+ +Q +
Sbjct: 288 QAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQK-GELNVQISERKTQLTLIKQEI 346
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEKLNGINKEELNEK 953
K+ + L+ + + +K +L + L L+ ++ + Q D+ +L L EK
Sbjct: 347 EKEEENLQVVLRQMSKHKTELQNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 406
Query: 954 ESLIIKQTKLFQQKAE 969
L Q QQK E
Sbjct: 407 LELENLQQISQQQKGE 422
>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
Golgi-localized PKN-associated protein (CG-NAP) protein.
Length = 3899
Score = 58.4 bits (135), Expect = 1e-07
Identities = 95/392 (24%), Positives = 172/392 (43%), Gaps = 40/392 (10%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
Q EK D+ Q+K L VEE IE EQ+ T D+ ++ +++ +K
Sbjct: 2011 QAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELM---DLRQQNQALEKQLEKMRK 2067
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
F + EQ +D E DV F+Q+I L ++K + Q + E +T
Sbjct: 2068 F--LDEQA--IDREHERDV-------FQQEIQKLEQQLKVV--------PRFQPISEHQT 2108
Query: 766 KAKEELLN-TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
+ E+L N ++K L SK+QLQ D I LE ++E ++A
Sbjct: 2109 REVEQLANHLKEKTDKCSELLLSKEQLQRD-------IQERNEEIEKLEFRVRELVQALL 2161
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLMEK 883
R++ +EA +V++ + DA ++ K+ N+ ++E+ +E + E+
Sbjct: 2162 VEDRKHFGAVEAKPELSLEVQLQAER----DAIDRKEKEITNLEEQLEQFREELENKNEE 2217
Query: 884 QKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLN 943
+Q+ ++ K+ T E+ ++ +D + L L ++D + Q Q L K
Sbjct: 2218 VQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQ-HVLFGKFA 2276
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTG--ALSELKKSLKGFRNELEKSLS-KDIEKKF 1000
I +E+ E + L + TKL QQ T + E + ++ ++E +S ++ K+
Sbjct: 2277 QIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRN 2336
Query: 1001 REKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
RE+ E + + I+K +E A K M H
Sbjct: 2337 REEEIE-QLNEVIEKLQQELANIGQKTSMNAH 2367
Score = 51.6 bits (118), Expect = 2e-05
Identities = 135/683 (19%), Positives = 291/683 (42%), Gaps = 61/683 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+E+ ++ N +++ +++ E ++EL+ KI + +K+T +LK+K + L + ++ IV K
Sbjct: 310 MEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK 369
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
N+ + L N +K+ + E ++ E + E
Sbjct: 370 NQEIKNMKLELTNSKQKE------RQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
Query: 513 SLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTVEKLQ-----DEQNVLQS-SMFII 565
+R+ E +AE D++Y Q + ++ +E+++ + +N L+S S +
Sbjct: 424 QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEIKTRHKGEMENALRSYSNITV 483
Query: 566 NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL-QRASAKKD 624
N+ + +L + + L N ++ + + L++ EDL + S +
Sbjct: 484 NEDQIKLMNVAINEL-NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRG 542
Query: 625 EI-LSMKSLNEKITTLKD-----TEIPQLEKRIVDVDTQIKTL------NETVEEITMSL 672
+I + +++ E+ + L + + + L+ IV K L T +I + +
Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 602
Query: 673 IEPEQKMTTAKQIHGDMPMLDRY-IQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ-- 729
+E E+ + L+R Q + + ++ +KE D++ E + + K
Sbjct: 603 LEKEKNAVLDRMAESQEAELERLSTQLLFSHEEELSKLKE---DLEIEHRISIEKLKDNL 659
Query: 730 -VDFKQKISTLRN----RVKTTQ-KKLNAHNKKLQTLYE-KKTKAKEELLNTQKKVQDIV 782
+ +KQ+I L+N +++T Q +K N K+ Q + E K K ++ L K + +
Sbjct: 660 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 719
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
+ E +K+++ E+ LK ++ K ++ + DL E + A
Sbjct: 720 QINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEK-QMKEKENDLQEKFAQLEA 775
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPRE---MEKIQ-EANDKLMEKQKQIM-TDRQVLTKK 897
+ + ++ K+L+ ++ H + ++ I+ ++ D + EK+ +I+ + + L ++
Sbjct: 776 ENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQ 835
Query: 898 IDTLKDEIAKQEVYKRDLDDN--LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L +EI KQ + N + ++ Q + K D+L + NK+EL K
Sbjct: 836 CIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSK---NKQELEYKSK 892
Query: 956 LIIKQTKLFQQKAECTGALSELKKSL----KGFRNELEKSLSKDIEKKFREKMYELHVTK 1011
L +L Q+ T ++K S+ K F E + + +EK E M L VTK
Sbjct: 893 LKALNEELNLQRINPTTV--KMKSSVFDEDKTFVAE-TLEMGEVVEKDTTELMENLEVTK 949
Query: 1012 AIDKDIREYAVALDKCLMEFHRE 1034
++ + L + L + H E
Sbjct: 950 REKLELSQRLSDLSEQLKQKHGE 972
Score = 44.8 bits (101), Expect = 0.002
Identities = 42/192 (21%), Positives = 89/192 (46%), Gaps = 15/192 (7%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
+ ++ + +R + + L L I+ L I +LE ++V++ T + E VE
Sbjct: 2567 QTISSEPERTNIQNLNQLREDELGSDISALT-LRISELESQVVEMHTSLILEKEQVEIAE 2625
Query: 670 MSLIEPEQKM---------TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ--CGDVDS 718
+++E E+K+ KQ + + ++ +KT T+ F + +E ++++
Sbjct: 2626 KNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTTELFHSNEESGFFNELEA 2685
Query: 719 EMTLDVAT-AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
VAT A+ +K+K L+ + + + + K L + + +AKE+L +K
Sbjct: 2686 LRAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEK- 2744
Query: 778 VQDIVNLEESKK 789
+D ++ESKK
Sbjct: 2745 -EDETEVQESKK 2755
Score = 44.0 bits (99), Expect = 0.003
Identities = 140/691 (20%), Positives = 288/691 (41%), Gaps = 95/691 (13%)
Query: 386 QAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKL------QKQTAKLKEKEMIEE 439
QAE + I+ ++EI E+ +EQ+ +E++ ++++ +L QK+ + + +E+ +E
Sbjct: 2184 QAERDA-IDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQE 2242
Query: 440 NLKTKEK-QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVR--NEVXXXXXXXXXX 496
N K+ + + L K A+ +V FA I + E E+ NE
Sbjct: 2243 NKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKI 2302
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDE-Q 555
+E + + IR+ E + E ++ + C + + + + +EKLQ E
Sbjct: 2303 TTDNKVIEEKNELIRDL--ETQIECLMSDQE----CVKRNREEEIEQLNEVIEKLQQELA 2356
Query: 556 NVLQSSMF---IINKYKGQLKDNSCCPLCNR-GFENESEXXXXXXXXXXXXMNVPG-KLE 610
N+ Q + +++ LK + + E + E + K+
Sbjct: 2357 NIGQKTSMNAHSLSEEADSLKHQLDVVIAEKLALEQQVETANEEMTFMKNVLKETNFKMN 2416
Query: 611 KVTEDL-----QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTL-NET 664
++T++L +R S +K + + S+N I L + P+LE +V + +K+L N+T
Sbjct: 2417 QLTQELFSLKRERESVEKIQSIPENSVNVAIDHLSKDK-PELE--VVLTEDALKSLENQT 2473
Query: 665 V-----EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSE 719
E S+I E ++ +Q+ + D E+ K+ + ++EQ G ++E
Sbjct: 2474 YFKSFEENGKGSIINLETRL---RQLESTVSAKDL---ELTQCYKQIKDMQEQ-GQFETE 2526
Query: 720 MTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ 779
M Q ++K++ +Q +L A + + + +T + E + +Q
Sbjct: 2527 MLQKKIVNLQKIVEEKVAA----ALVSQIQLEAVQEYAKFCQDNQTISSEP---ERTNIQ 2579
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVAL---KEKIE-AKTEVVRRNRDLIE 835
++ L E +L SD + + +L KE++E A+ V+ + + L+E
Sbjct: 2580 NLNQLRED--ELGSDISALTLRISELESQVVEMHTSLILEKEQVEIAEKNVLEKEKKLLE 2637
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQ-IMTDRQVL 894
+ K+ + N+ K + E KK P+++E ++ + ++ + + L
Sbjct: 2638 -----LQKL-LEGNEKKQREKE-----KKRSPQDVEVLKTTTELFHSNEESGFFNELEAL 2686
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNLCLRKA-----QTDITNWQKQDDELNEKLNGINKEE 949
+ K E+A + L + L +++ Q D++ + E EKL+ + KE+
Sbjct: 2687 RAESVATKAELASYKEKAEKLQEELLVKETNMTSLQKDLSQVRDHLAEAKEKLSILEKED 2746
Query: 950 LNEK---------ESLIIKQTKLFQQKAECTGALSELKKSLK------GFRNELEKSLSK 994
E E L IK +K + + T +S ++ + G + L+ S
Sbjct: 2747 ETEVQESKKACMFEPLPIKLSKSIASQTDGTLKISSSNQTPQILVKNAGIQINLQSECSS 2806
Query: 995 D----IEKKFREK---MYELHVTKAIDKDIR 1018
+ I +F EK M ELH + +D + R
Sbjct: 2807 EEVTEIISQFTEKIEKMQELHAAEILDMESR 2837
Score = 43.6 bits (98), Expect = 0.004
Identities = 112/648 (17%), Positives = 267/648 (41%), Gaps = 71/648 (10%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDEL-SQKITKLQKQTAKLKEKEMIEENLK 442
HK ++ E +I + ++ E ++ +EQ E+DE+ Q+I +++++ + +M E +
Sbjct: 409 HKDSQFETDIVQRMEQ--ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEIKTR 466
Query: 443 TKEKQLIVLKNKHKTALME---LLGNVPEKDFAVTI---NKFECEVRNEVXXXXXXXXXX 496
K + L++ + E L NV + + + N + +++ E+
Sbjct: 467 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 526
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQN 556
L E R + R + + E K+ +A + L + + + E
Sbjct: 527 QRQLEDLVEELSFSRGQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE 586
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + K K ++ + + +R ES+ + +L K+ EDL
Sbjct: 587 LKHEAEVTNYKIKLEMLEKEKNAVLDR--MAESQEAELERLSTQLLFSHEEELSKLKEDL 644
Query: 617 Q---RASAKK----------DEILSMKS-LNEKITTL---KDTEIPQLEKRIVDV----D 655
+ R S +K +I +++ +++KI T+ KD I + + I+++ D
Sbjct: 645 EIEHRISIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKD 704
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEA------- 708
Q +N EE+T+ + E ++++ +Q + L++ +QE++ T+ E
Sbjct: 705 LQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 764
Query: 709 -VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK--------TTQKKLNAHNKKLQT 759
++E+ +++E ++ K ++ KI T ++ + ++ K + K+++
Sbjct: 765 DLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEI 824
Query: 760 LYEKKTKAKEELLNTQKKVQD--------IVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
L E+ K++ + ++++ N E + ++LQ + +
Sbjct: 825 LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNK 884
Query: 812 LEVALKEKIEAKTE----------VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
E+ K K++A E V+ + + ++A+ V+ E+ ++
Sbjct: 885 QELEYKSKLKALNEELNLQRINPTTVKMKSSVFDEDKTFVAETLEMGEVVEKDTTELMEN 944
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
+ ++E Q +D L E+ KQ + L +++ +LK E + + R+L+ +
Sbjct: 945 LEVTKREKLELSQRLSD-LSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINH 1003
Query: 922 RKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
+A+ D+ + Q+ L L+G+ E + K K F ++++
Sbjct: 1004 NRAE-DVQSCDTQESSL---LDGVVTMTSRGAEGSVSKVNKSFGEESK 1047
Score = 40.3 bits (90), Expect = 0.041
Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVY 911
+ L + QQ + R A D L KQ QI+T +Q L ++ L+D K+E
Sbjct: 236 QKLQIQFQQLQASETLRNSTHSSTAADLLQAKQ-QILTHQQQLEEQDHLLEDYQKKKE-- 292
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAEC 970
D + + Q I ++ + D +K+ NKEE+ EKE++I + TK+ +++ +
Sbjct: 293 ----DFTMQISFLQEKIKVYEMEQD---KKVENSNKEEIQEKETIIEELNTKIIEEEKKT 345
Query: 971 TGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
ELK L L + + ++K K +L +T + K+
Sbjct: 346 L----ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE 387
Score = 39.9 bits (89), Expect = 0.054
Identities = 54/261 (20%), Positives = 107/261 (40%), Gaps = 16/261 (6%)
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQ 792
K K+ +L+ R + +K H K LQT E T+ ++++ Q KV+D+ E K+Q
Sbjct: 3360 KYKLDSLQTR-QQMEKDRQVHRKTLQTEQEANTEGQKKMHELQSKVEDLQRQLEEKRQQV 3418
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
E+ +EK E++ ++ +N + + + + N V
Sbjct: 3419 YKLDLEGQRLQGIMQEFQKQELEREEKRESR-RILYQN---LNEPTTWSLTSDRTRNWV- 3473
Query: 853 SLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYK 912
L +I+ K++ ++ ++ + + I Q + K+ L + +++ ++
Sbjct: 3474 -LQQKIEGETKESNYAKLIEMNGGGTGCNHELEMIRQKLQCVASKLQVLPQKASERLQFE 3532
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE---LNEKESLIIKQTKLFQQKAE 969
D++ + D Q Q KL G EE ++ S +L +Q AE
Sbjct: 3533 TADDEDFIWVQENIDEIILQLQ------KLTGQQGEEPSLVSPSTSCGSLTERLLRQNAE 3586
Query: 970 CTGALSELKKSLKGFRNELEK 990
TG +S+L + RN + K
Sbjct: 3587 LTGHISQLTEEKNDLRNMVMK 3607
Score = 35.5 bits (78), Expect = 1.2
Identities = 22/116 (18%), Positives = 57/116 (49%), Gaps = 4/116 (3%)
Query: 215 VKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVET 274
++ + K +D +K KE + ++ + + + KF + + + +ID+ NEQ+ +
Sbjct: 2239 LEQENKLFKDDMEKLGLAIKESDAMSTQ--DQHVLFGKFAQIIQEKEVEIDQLNEQVTKL 2296
Query: 275 AKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+ +++ T+ + EE + + ++E L SD + K +EE ++ +++
Sbjct: 2297 QQ--QLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEK 2350
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 58.0 bits (134), Expect = 2e-07
Identities = 148/828 (17%), Positives = 311/828 (37%), Gaps = 58/828 (7%)
Query: 172 KKVKERFDEIFDADKYSDCL-DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT 230
K++K + K ++ L +L+ K+ + + L ++ T A ++ + K
Sbjct: 540 KEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELK--V 597
Query: 231 SFNKEEEKIANEKSSNEIEYNKFILLESQNQEKI-DKRNEQIVETAKIAEIENITEVQTN 289
SF+K E + + + K L E + +++N + AK E ++
Sbjct: 598 SFSKGLGAETAEFAELKTQIEKMRLDYQHEIENLQNQQNSERAAHAKEMEALRAKLMKVI 657
Query: 290 EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECR--SGHTQXXXXXXXXXX 347
+E EN+ + I K++ + H V+ + ++A+ V E
Sbjct: 658 KEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFT 717
Query: 348 XXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAV 407
D+ + ++ ++ L IE+ N +
Sbjct: 718 SQPKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQIKHLEIEK-----NAESSKA 772
Query: 408 EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
+E+ K+T LQ+ L E ++E L EK+L +LK K A E +
Sbjct: 773 SSITRELQGRELKLTNLQEN---LSEVSQVKETL---EKELQILKEKFAEASEEAVS--V 824
Query: 468 EKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDK 527
++ T+NK + + +EA+ RE +ER +L KA++K
Sbjct: 825 QRSMQETVNKLH-QKEEQFNMLSSDLEKLRENLADMEAK---FREK-DEREEQLIKAKEK 879
Query: 528 IYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFEN 587
+ ++ + K+ DE + + + + + +N+ + E+
Sbjct: 880 LENDIAE--IMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENAS--FLQKSIED 935
Query: 588 ESEXXXXXXXXXXXXMNVPGK-LEKVTEDLQRA-SAKKDEILSMKSLNEKITT---LKDT 642
+ K LE+ DL++ ++ +K+ E+ T+ K
Sbjct: 936 MTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHE 995
Query: 643 EIPQ-LEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK--QIHGD-MPMLDRYIQE 698
EI Q L+K ++D + ++K E + L E ++ AK Q D M ++++ +E
Sbjct: 996 EILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKE 1055
Query: 699 IKTVTKKFEAVKEQCGDVDSEM-TLDVATAKQVDF-----------KQKISTLRNRVKTT 746
E K+ + +E+ TL K V+ QK+ R ++T
Sbjct: 1056 KTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETL 1115
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXX 806
++ +++L L E+ K EEL ++ +V LEE + L +
Sbjct: 1116 KQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFI 1175
Query: 807 XAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNV 866
+ +L++ I + ++ +E + + KSL + +Q + V
Sbjct: 1176 KDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKV 1235
Query: 867 PREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC--LRKA 924
E+ K++ +L E ++Q+ + + DT DE + + + D +++ L++
Sbjct: 1236 KLEL-KVKNLELQLKENKRQLSSS----SGNTDTQADEDERAQESQIDFLNSVIVDLQRK 1290
Query: 925 QTDITNWQKQDDE--LNEKLNGINKEELNEKESLIIKQTKLFQQKAEC 970
D+ + E LN + +N + +++E K+ +LF +C
Sbjct: 1291 NQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLFCDICDC 1338
Score = 57.2 bits (132), Expect = 3e-07
Identities = 179/990 (18%), Positives = 396/990 (40%), Gaps = 93/990 (9%)
Query: 70 AKVNRSTEVLGQVKLKIVNAKDKQ----LEVTRSMKVTALAKKKTKFQTLDSFLSTVDES 125
A+V ++T +G+++ ++ A+D LE+ M + + ++ +E
Sbjct: 376 AEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEK 435
Query: 126 GKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDE---IF 182
K +D+ R + + + +L V+ S + ++D + + E +++ R +
Sbjct: 436 RKVEDLQFRVEE-ESITKGDLEVATVSEKSRIMELEKDLALRVQEVAELRRRLESNKPAG 494
Query: 183 DAD-------KYSDCLDRLKKIRKDYAQNL-KLLENYATTVKAKQKELEDSYKKNTSFNK 234
D D + S ++L+ R D+ + + L E++ + QKE++ Y +K
Sbjct: 495 DVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREETHQKEIKALYTATEKLSK 554
Query: 235 EEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAEN 294
E E + ++ E + I L E ++Q +E K++ + + +T E AE
Sbjct: 555 ENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGL-GAETAEFAE- 612
Query: 295 ATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXX 354
KT +EK+ L H+++ Q + + R+ H +
Sbjct: 613 -LKTQIEKMR-LDYQHEIENLQNQQNSE---------RAAHAK----EMEALRAKLMKVI 657
Query: 355 XXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEE---CQQEINEDEKAVEQYE 411
+ A +S +K E E+ ++E Q + NE K ++ +
Sbjct: 658 KEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNEQTKVIDNFT 717
Query: 412 QEMDELSQK---ITKLQKQTAKLK-EKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVP 467
+ +K + L+K +++ K E + + + L+ EKQ+ KH +E+ N
Sbjct: 718 SQPKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQI-----KH----LEIEKNA- 767
Query: 468 EKDFAVTINKFECEVRN-EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAED 526
E A +I + E + R ++ LE E + ++E E E +
Sbjct: 768 ESSKASSITR-ELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSVQR 826
Query: 527 KIYKACG-TQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQL------KDNSCCP 579
+ + + + ++ +EKL++ +++ ++ + QL +N
Sbjct: 827 SMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAE 886
Query: 580 LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS--AKKDEILSMKSLNEKIT 637
+ +N S+ +V K+T+ + AS K E +++K+ +
Sbjct: 887 IMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQE 946
Query: 638 TLK--DTEIPQLEKRIVDVDTQIKTLNETVEEI----TMSLIEPEQK-----MTTAKQIH 686
K + E +LE+++ D++ +++T + +E+ + E + K K +
Sbjct: 947 AAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLL 1006
Query: 687 GDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL-DVATAKQVDFKQKISTLRNRVKT 745
L +E + ++ E +++Q + T D + K+K TL + T
Sbjct: 1007 DTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDT 1066
Query: 746 TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN--LEESKKQLQSDCXXXXXXXX 803
Q N +L TL E K EE LN K++ + N +EE +K++++
Sbjct: 1067 KQTNAKLQN-ELDTLKENNLKNVEE-LNKSKELLTVENQKMEEFRKEIET-LKQAAAQKS 1123
Query: 804 XXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSA---YIAKVEVAFNK-VKSLDAEIQ 859
A+ V L E++ + V ++ L E S + +++ +K +K D E +
Sbjct: 1124 QQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLEMKKRESKFIKDADEE-K 1182
Query: 860 QHKKKNVPREMEKIQEANDKLMEKQKQIMTDR------QVLTKKIDTLKDEIAKQEVYKR 913
+K++ + E + +L + + ++ R + L + TL+ + K E+ +
Sbjct: 1183 ASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVK 1242
Query: 914 DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGA 973
+L+ L L++ + +++ D ++ + +++ S+I+ + Q
Sbjct: 1243 NLE--LQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEM 1300
Query: 974 LSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
+SE +L G ++L S D EK+ ++K
Sbjct: 1301 MSE--AALNGNGDDLNNYDSDDQEKQSKKK 1328
Score = 45.6 bits (103), Expect = 0.001
Identities = 93/459 (20%), Positives = 206/459 (44%), Gaps = 50/459 (10%)
Query: 621 AKKDEILSMKSL--NEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
AK D++ +M EK+ L E EKR V+ D Q + E++ + + + +K
Sbjct: 408 AKMDQLRTMVEAADREKVELLNQLEE---EKRKVE-DLQFRVEEESITKGDLEVATVSEK 463
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL--DVATAKQ------V 730
+ ++ D+ + +QE+ + ++ E+ K GDVD ++L ++++ ++
Sbjct: 464 -SRIMELEKDLALR---VQEVAELRRRLESNKP-AGDVDMSLSLLQEISSLQEKLEVTRT 518
Query: 731 DFKQKISTLRN----RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
D +++I++L+ R +T QK++ A + L ++ K +L + K+ D++ L +
Sbjct: 519 DHQREITSLKEHFGAREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWK 578
Query: 787 SKKQL-----QSDCXXXXXXXXXXXXAITPLEVALKEKIEA-----KTEVVRRNRDLIEA 836
SK + Q A T LK +IE + E+
Sbjct: 579 SKLETAIASHQQAMEELKVSFSKGLGAETAEFAELKTQIEKMRLDYQHEIENLQNQQNSE 638
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+A+ ++E K+ + E +++ + + +++K ++ + ME + + ++ K
Sbjct: 639 RAAHAKEMEALRAKLMKVIKE-KENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVK 697
Query: 897 KIDTLKDEIAKQ-EVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE-ELNEKE 954
+++ L+ + +Q +V + D+ +K E ++ + ++ E EK+
Sbjct: 698 ELEVLQAKCNEQTKVIDNFTSQPKATEEKLLDLDALRKASSEGKSEMKKLRQQLEAAEKQ 757
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFR---NELEKSLSKDIE-KKFREKMYELHVT 1010
IK ++ ++ AE + A S + + L+G L+++LS+ + K+ EK EL +
Sbjct: 758 ---IKHLEI-EKNAESSKA-SSITRELQGRELKLTNLQENLSEVSQVKETLEK--ELQIL 810
Query: 1011 KAIDKDIREYAVALDKCLMEF---HREKMENINMIIREL 1046
K + E AV++ + + E +K E NM+ +L
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDL 849
Score = 32.7 bits (71), Expect = 8.2
Identities = 52/268 (19%), Positives = 112/268 (41%), Gaps = 17/268 (6%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMK-VTALAKKKTKFQTLDSFLSTVDESG 126
H+ + + L + K+ A+++ + + ++ + A K QT + + +++
Sbjct: 994 HEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDAMQIMEQM- 1052
Query: 127 KTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFD-EIFDAD 185
TK+ + A L E+ + A L + + +E++ ++E K KE E +
Sbjct: 1053 -TKEKTETLASL-----EDTKQTNAKLQNELDTLKENNLKNVEELNKSKELLTVENQKME 1106
Query: 186 KYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSS 245
++ ++ LK+ +Q L L+ + + D + +E + N+
Sbjct: 1107 EFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSVLNNQLLE 1166
Query: 246 NEIEYNKFILLESQNQEKIDKRNE--QIVETAKIAEIENITEVQTNEEAENAT-KTILEK 302
+ +KFI + + + K + T K AE+E + T ENA+ K++
Sbjct: 1167 MKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASAKSLHSV 1226
Query: 303 VESLKSDH-----KVQKSQADEEEKKAQ 325
V++L+SD KV+ + +E K Q
Sbjct: 1227 VQTLESDKVKLELKVKNLELQLKENKRQ 1254
>AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein
protein.
Length = 1177
Score = 58.0 bits (134), Expect = 2e-07
Identities = 79/440 (17%), Positives = 186/440 (42%), Gaps = 24/440 (5%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LE++ ++LQ+A + E+ + E + E+ L KR+++++ + + + +T +
Sbjct: 344 ELEEINKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQ 403
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ +++ +K++ ++ L + + E++ + + F K +C + + +
Sbjct: 404 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLT 463
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDIVNL 784
K D ++ +++RVK + + K +L + TK K L++ +K + + +
Sbjct: 464 K--DLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 521
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
EE K + L K+ ++ K+E+ + +L I K+
Sbjct: 522 EERK--VDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKL 579
Query: 845 EVAFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQV--LTKKIDTL 901
+ K L + KK+ + E+E+ + D ++ LT +I+ L
Sbjct: 580 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 639
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
K + + EV + D L K + + +++ +K N ++ ++L E + I K
Sbjct: 640 KKRLQQLEVVEGD------LMKTEDEYDQLEQKFRTEQDKANFLS-QQLEEIKHQIAKNK 692
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ +K E +EL+ R LE++ S+D++ + + ++H + + +
Sbjct: 693 AI--EKGEVVSQEAELR-----HRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQ 745
Query: 1022 VALDKCLMEFHREKMENINM 1041
V F E+ +N NM
Sbjct: 746 VDYSVLQQRFMEEENKNKNM 765
Score = 40.3 bits (90), Expect = 0.041
Identities = 104/587 (17%), Positives = 237/587 (40%), Gaps = 50/587 (8%)
Query: 385 KQAENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN 440
K+ EN + + + E+ + + V++ + +++L + K+Q T KL+E+E +
Sbjct: 225 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKA 284
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXX 500
+ +K K+ ++ K +E+ F+ + ++ N+
Sbjct: 285 ITSKSKE-----DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLT 339
Query: 501 XXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E + I ++L + EL + DKI K CG S VE L+ + VL+
Sbjct: 340 QRIE-ELEEINKNLQKAEEELQELRDKIAKGECGN-------SSLMAEVENLR--KRVLE 389
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
K + K S C + + E +LEK+ E ++
Sbjct: 390 ME----GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKS 445
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ ++ + +T E+ ++ R+ +++ L + E+++ + K
Sbjct: 446 KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA--ELSLKDDLTKLKS 503
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T + M+++ QE + V + K + G V +DV T K ++ +K+ L
Sbjct: 504 FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-----MDV-TEKLIEESKKLLKL 557
Query: 740 RNRVKTTQKKLNAHNKKL-QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
++ ++ L +L L ++ K+ E + + + +EE ++++
Sbjct: 558 KSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREI------T 611
Query: 799 XXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI 858
P + +KE + + E +++ +E + K E +++++
Sbjct: 612 RGRSRKGSELTCPEDNKIKE-LTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRT 669
Query: 859 QQHKKKNVPREMEKI--QEANDKLMEKQKQIMTDRQVLTK-KIDTLKDEIAKQEV--YKR 913
+Q K + +++E+I Q A +K +EK + + + ++ + +++ K K EV K
Sbjct: 670 EQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKE 729
Query: 914 DLDDNL----CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
+ + + L + Q D + Q++ E K + +E LN + L
Sbjct: 730 KIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKEL 776
Score = 35.9 bits (79), Expect = 0.88
Identities = 83/424 (19%), Positives = 175/424 (41%), Gaps = 27/424 (6%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
HK + EE ++ E Q ++ L+Q+I +L++ L++ E + L+
Sbjct: 305 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEEINKNLQKAEEELQELRD 364
Query: 444 KEKQLIVLKNKHKTALMELLGNVPE---KDFAVTINKFEC-EVRNEVXXXXXXXXXXXXX 499
K + + + L V E KD +T + +C E+R ++
Sbjct: 365 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 424
Query: 500 XXXLE---AERKHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQ 555
L+ +E + + E+ ++ +SE T+ + K T+ L + V++L+ +
Sbjct: 425 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 484
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRG--FENESEXXXXXXXXXXXXMNVPGKLEKVT 613
+ L+ + + +LK + + R E + GK+ VT
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 544
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E L S K +L +KS + EK+ L E +L ++ + + L+ +V+ + L
Sbjct: 545 EKLIEESKK---LLKLKSEMEEKVYNL-TRERDELIGKLKSEEEKSSELSCSVDLLKKRL 600
Query: 673 --IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
IE ++ T + + +IK +T + E +K++ L+V +
Sbjct: 601 DGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL------QQLEVVEGDLM 654
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK--KTKA--KEELLNTQKKVQDIVNLEE 786
+ + L + +T Q K N +++L+ + + K KA K E+++ + +++ LEE
Sbjct: 655 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEE 714
Query: 787 SKKQ 790
+K +
Sbjct: 715 AKSR 718
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 57.6 bits (133), Expect = 3e-07
Identities = 101/521 (19%), Positives = 215/521 (41%), Gaps = 37/521 (7%)
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMF 563
E E ++E + L K+E + K + + K ++ ++ N+ +
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEAR-RKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER 904
Query: 564 IINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKK 623
K +++ + N E+E E + +L++ +DL+ AK
Sbjct: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKV 964
Query: 624 DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT-- 681
++ + K+ L + E+ L++ I + + K L E ++ L E K+ T
Sbjct: 965 EK--EKHATENKVKNLTE-EMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLT 1021
Query: 682 -AK-QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
AK ++ + L+ +++ K V E K + E L + +D + L
Sbjct: 1022 KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL-----EGDLKLTQESIMDLENDKQQL 1076
Query: 740 RNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKK-------QLQ 792
R+K +LNA N +++ ++ +++L Q +++++ ES++ +L+
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLR 1136
Query: 793 SDCX---XXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
SD T +++ + +K EA+ + +R RDL EA + A
Sbjct: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR--RDLEEATLQHEATAAALRK 1194
Query: 850 K----VKSLDAEIQ--QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD 903
K V L +I Q K+ + +E + + D + +QI+ + L K TL+D
Sbjct: 1195 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 904 EI----AKQEVYKRDLDDNLCLR-KAQTDITNWQKQDDELNEKLNGINKEELNEKESLII 958
++ +K E +R ++D R K QT+ +Q DE ++ + + +L + L
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ +L +++ + AL+ +S + + L + ++ E K
Sbjct: 1315 LKRQL-EEEVKAKNALAHALQSARHDCDLLREQYEEETEAK 1354
Score = 52.0 bits (119), Expect = 1e-05
Identities = 160/850 (18%), Positives = 349/850 (41%), Gaps = 82/850 (9%)
Query: 172 KKVKERFDEIFDA-DKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKN 229
K+++ R +E+ + + +++K+R D ++ L+ + E A ++E + K+
Sbjct: 1109 KELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168
Query: 230 TSFNK-----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIEN 282
F K EE + +E ++ + K ++ E+ID +R +Q +E K
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 283 ITEVQTNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXX 341
+ +V +N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 342 XXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEIN 401
+T Q +A+N L Q +
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARH 1338
Query: 402 EDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
+ + EQYE+E + EL + ++K + A+ + K + +T+E L K K
Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQR 1396
Query: 459 LMELLGNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNER 517
L E V + + + K + ++NE+ L+ ++++ + L E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 518 RSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--N 575
+ + +++ ++ + Q +LS T + KL+ N + S+ + +K + K+
Sbjct: 1457 KQKYEESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQE 1507
Query: 576 SCCPLCNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILS 628
L + G ++ E M + LE+ L+ K + E
Sbjct: 1508 EISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQ 1567
Query: 629 MKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGD 688
+K+ E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD
Sbjct: 1568 IKAEIERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGD 1621
Query: 689 MPMLDRYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTT 746
+ ++ + + + + + + D+++ LD A D K+ I+ + R
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXX 802
Q +L ++ + A++EL+ T ++VQ + +L KK++ +D
Sbjct: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ--- 1738
Query: 803 XXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK 862
T +E A++E A+ + + D +A +A+ K + A +++
Sbjct: 1739 -------TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-M 1782
Query: 863 KKNVPREMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
KKN+ + ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +
Sbjct: 1783 KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGM 1840
Query: 922 RKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSL 981
RK++ I Q +E ++ N + ++L +K L +K K ++AE A + L K
Sbjct: 1841 RKSERRIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFR 1897
Query: 982 KGFRNELEKS 991
K ++EL+++
Sbjct: 1898 K-VQHELDEA 1906
Score = 41.5 bits (93), Expect = 0.018
Identities = 34/162 (20%), Positives = 82/162 (50%), Gaps = 11/162 (6%)
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC-LRKAQTDIT-NWQKQDD 936
K E++K++ + ++ T+ LK+ + K E +++L++ + L + + D+ Q + D
Sbjct: 841 KSAEREKEMASMKEEFTR----LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 937 EL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLS 993
L E+ + + K ++ + E+ + + + + + E L+ K+ L+ +EL++ +
Sbjct: 897 NLADAEERCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDID 955
Query: 994 KDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
D+E + E H T+ K++ E LD+ + + +EK
Sbjct: 956 -DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEK 996
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 57.6 bits (133), Expect = 3e-07
Identities = 101/521 (19%), Positives = 215/521 (41%), Gaps = 37/521 (7%)
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMF 563
E E ++E + L K+E + K + + K ++ ++ N+ +
Sbjct: 846 EKEMASMKEEFTRLKEALEKSEAR-RKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEER 904
Query: 564 IINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKK 623
K +++ + N E+E E + +L++ +DL+ AK
Sbjct: 905 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKV 964
Query: 624 DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT-- 681
++ + K+ L + E+ L++ I + + K L E ++ L E K+ T
Sbjct: 965 EK--EKHATENKVKNLTE-EMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNTLT 1021
Query: 682 -AK-QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
AK ++ + L+ +++ K V E K + E L + +D + L
Sbjct: 1022 KAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL-----EGDLKLTQESIMDLENDKQQL 1076
Query: 740 RNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKK-------QLQ 792
R+K +LNA N +++ ++ +++L Q +++++ ES++ +L+
Sbjct: 1077 DERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELESERTARAKVEKLR 1136
Query: 793 SDCX---XXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
SD T +++ + +K EA+ + +R RDL EA + A
Sbjct: 1137 SDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR--RDLEEATLQHEATAAALRK 1194
Query: 850 K----VKSLDAEIQ--QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKD 903
K V L +I Q K+ + +E + + D + +QI+ + L K TL+D
Sbjct: 1195 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 904 EI----AKQEVYKRDLDDNLCLR-KAQTDITNWQKQDDELNEKLNGINKEELNEKESLII 958
++ +K E +R ++D R K QT+ +Q DE ++ + + +L + L
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ +L +++ + AL+ +S + + L + ++ E K
Sbjct: 1315 LKRQL-EEEVKAKNALAHALQSARHDCDLLREQYEEETEAK 1354
Score = 52.0 bits (119), Expect = 1e-05
Identities = 160/850 (18%), Positives = 349/850 (41%), Gaps = 82/850 (9%)
Query: 172 KKVKERFDEIFDA-DKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKN 229
K+++ R +E+ + + +++K+R D ++ L+ + E A ++E + K+
Sbjct: 1109 KELQARIEELEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1168
Query: 230 TSFNK-----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIEN 282
F K EE + +E ++ + K ++ E+ID +R +Q +E K
Sbjct: 1169 AEFQKMRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLE 1227
Query: 283 ITEVQTNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXX 341
+ +V +N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 1228 LDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGEL 1287
Query: 342 XXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEIN 401
+T Q +A+N L Q +
Sbjct: 1288 SRQLDEKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARH 1338
Query: 402 EDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTA 458
+ + EQYE+E + EL + ++K + A+ + K + +T+E L K K
Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQR 1396
Query: 459 LMELLGNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNER 517
L E V + + + K + ++NE+ L+ ++++ + L E
Sbjct: 1397 LQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEW 1456
Query: 518 RSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--N 575
+ + +++ ++ + Q +LS T + KL+ N + S+ + +K + K+
Sbjct: 1457 KQKYEESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQE 1507
Query: 576 SCCPLCNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILS 628
L + G ++ E M + LE+ L+ K + E
Sbjct: 1508 EISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQ 1567
Query: 629 MKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGD 688
+K+ E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD
Sbjct: 1568 IKAEIERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGD 1621
Query: 689 MPMLDRYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTT 746
+ ++ + + + + + + D+++ LD A D K+ I+ + R
Sbjct: 1622 LNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLL 1681
Query: 747 QKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXX 802
Q +L ++ + A++EL+ T ++VQ + +L KK++ +D
Sbjct: 1682 QAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ--- 1738
Query: 803 XXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK 862
T +E A++E A+ + + D +A +A+ K + A +++
Sbjct: 1739 -------TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-M 1782
Query: 863 KKNVPREMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
KKN+ + ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +
Sbjct: 1783 KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGM 1840
Query: 922 RKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSL 981
RK++ I Q +E ++ N + ++L +K L +K K ++AE A + L K
Sbjct: 1841 RKSERRIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFR 1897
Query: 982 KGFRNELEKS 991
K ++EL+++
Sbjct: 1898 K-VQHELDEA 1906
Score = 41.5 bits (93), Expect = 0.018
Identities = 34/162 (20%), Positives = 82/162 (50%), Gaps = 11/162 (6%)
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC-LRKAQTDIT-NWQKQDD 936
K E++K++ + ++ T+ LK+ + K E +++L++ + L + + D+ Q + D
Sbjct: 841 KSAEREKEMASMKEEFTR----LKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD 896
Query: 937 EL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLS 993
L E+ + + K ++ + E+ + + + + + E L+ K+ L+ +EL++ +
Sbjct: 897 NLADAEERCDQLIKNKI-QLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDID 955
Query: 994 KDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
D+E + E H T+ K++ E LD+ + + +EK
Sbjct: 956 -DLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEK 996
>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
Length = 1726
Score = 57.6 bits (133), Expect = 3e-07
Identities = 161/820 (19%), Positives = 319/820 (38%), Gaps = 60/820 (7%)
Query: 187 YSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
Y ++L++ + Y + +++ + +++ + EL + K N + +E A + S
Sbjct: 825 YEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELR-TVKSNLNQVVQERNDAQRQLSR 883
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E N +L + + K+ E I K EN + ++ + + E++ L
Sbjct: 884 E--QNARMLQDGILTNHLSKQKE-IEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAML 940
Query: 307 KSDHKVQKSQADEEEKKA---QGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSA 363
+ + K+Q E+EKK V E + +T+
Sbjct: 941 RLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAE 1000
Query: 364 NQSXXXXXXXXXXXXXXXXXHKQAENE---LNIEECQQEINEDEKAVEQYEQEMDELSQK 420
N ++ + I + Q + +++ DE S+
Sbjct: 1001 NAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRL 1060
Query: 421 ITKLQKQTAKLKEK-EMIEENLKTKEKQLIVLKNK-HKT--ALME-LLG-NVPEKDFAVT 474
K+ + LK+ E++ + L E +L L+ + H T AL E LG +KD + T
Sbjct: 1061 QDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQT 1120
Query: 475 ---INKFECEVRNE---VXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI 528
+ + E + +NE V L++E +R+ L++ + KA++K
Sbjct: 1121 QCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHN---KADNKE 1177
Query: 529 YKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENE 588
Q ++ V+KLQ E + S+ + + K + + C L R ++ E
Sbjct: 1178 KTVINIQ------DQFHAIVQKLQAESE--KQSLLLEERNKELISE--CNHLKERQYQYE 1227
Query: 589 SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN-EKITTLKDTEIPQL 647
+E + L+K + + AS E+ S +N E T ++ Q+
Sbjct: 1228 NEKAEREVVVRQLQQELADTLKK--QSMSEASL---EVTSRYRINLEDETQDLKKKLGQI 1282
Query: 648 EKRIVDVD---TQIKTLNETVEEITMSLIEPEQKM-TTAKQIHGDMPMLDRYIQEIKTVT 703
++ + T+ E +++ L + K+ T K+ + L + +
Sbjct: 1283 RNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSE 1342
Query: 704 KKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAH-NKKLQTLY 761
+ E +K+ S E LD K V+ +++I+ +N +K T+KKLN + N +
Sbjct: 1343 DEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHG 1402
Query: 762 EKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE 821
+ KT E + K I +L + S C + ++ K+ +
Sbjct: 1403 DLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEK 1462
Query: 822 AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLM 881
+ + +++I S +I + V +VK EI++ ++ + EK++E N L
Sbjct: 1463 LQKNKKKLEQEVINLRS-HIERNMVELGQVKQYKQEIEERARQEI---AEKLKEVNLFLQ 1518
Query: 882 EKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK 941
+ Q ++K ++ E+ +DL+ L K +T ++ K EL EK
Sbjct: 1519 AQAASQENLEQFRENNFASMKSQM---ELRIKDLESE--LSKIKTSQEDFNK--TEL-EK 1570
Query: 942 LNGINKEELNEKESLIIKQTKLFQQKAEC-TGALSELKKS 980
+ EEL ++SL K TK ++ AE T L E ++S
Sbjct: 1571 YKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQS 1610
Score = 37.9 bits (84), Expect = 0.22
Identities = 84/500 (16%), Positives = 209/500 (41%), Gaps = 48/500 (9%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
+E E N ++ QYE E E + +LQ++ A LK++ M E +L+ + I L+
Sbjct: 1210 KELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLE 1269
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
++ + L + LG + N+ + E ++ LE + ++
Sbjct: 1270 DETQD-LKKKLGQIR--------NQLQ-EAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKV 1319
Query: 513 SLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQ-DEQNVLQSSMFI---INKY 568
++ ++ ++ + + + A ++ L K + L+ + ++ ++ + I +
Sbjct: 1320 TVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGF 1379
Query: 569 KGQLK--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK---- 622
K LK N F + + K++ +T +L+ A +K
Sbjct: 1380 KNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHL 1439
Query: 623 -------KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
++E+LSMK++ +K L+ + +LE+ ++++ + I+ + ++ E
Sbjct: 1440 DTKNQILQEELLSMKTVQKKCEKLQKNK-KKLEQEVINLRSHIERNMVELGQVKQYKQEI 1498
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ-CGDVDSEMTLDVATAKQVDFKQ 734
E++ ++I + ++ ++Q + E +E + S+M L + D +
Sbjct: 1499 EER--ARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIK-----DLES 1551
Query: 735 KISTLRNRVKTTQKKLNAHN-KKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQS 793
++S ++KT+Q+ N +K + LY ++ K ++ L + K + + +K ++
Sbjct: 1552 ELS----KIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEK 1607
Query: 794 DCXXXXXXXXXXXXAITPLEVA-LKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
+ P V L ++ +++ R +I + + N ++
Sbjct: 1608 QQSRSLFTTLTTRPVMEPPCVGNLNNSLDLNRKLIPRENLVISTSNPRASN-----NSME 1662
Query: 853 SLDAEIQQHKKKNVPREMEK 872
+ +++QQ +KN+ RE+++
Sbjct: 1663 NYLSKMQQELEKNITRELKE 1682
Score = 35.9 bits (79), Expect = 0.88
Identities = 57/291 (19%), Positives = 132/291 (45%), Gaps = 33/291 (11%)
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
++V++++++ +LR + ++K + TLYEK +E+L +++ + V E
Sbjct: 796 QKVEWERELCSLRFSLNQEEEK----RRNADTLYEK---IREQLRRKEEQYRKEV---EV 845
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR-RNRDLIEAGSAYIAKVEV 846
K+QL+ + L ++E+ +A+ ++ R +N +++ G +
Sbjct: 846 KQQLELSLQTLEMELRTVK---SNLNQVVQERNDAQRQLSREQNARMLQDG--------I 894
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
N + S EI+ +KK +E D L K + + +L +IDT+K++
Sbjct: 895 LTNHL-SKQKEIEMAQKKMNSENSHSHEEEKD-LSHKNSMLQEEIAMLRLEIDTIKNQ-- 950
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDE-LNEKLNGINKEELNEKESLIIKQTKLFQ 965
QE K+ +D +++ D+ KQ++E L + ++ + N + S++ + +
Sbjct: 951 NQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTIS-----QYNGRLSVLTAENAMLN 1005
Query: 966 QKAECTGALSE-LKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
K E E L+ ++ + + L ++ + + ++ EL +A D+
Sbjct: 1006 SKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDE 1056
>BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1107
Score = 57.6 bits (133), Expect = 3e-07
Identities = 105/504 (20%), Positives = 219/504 (43%), Gaps = 41/504 (8%)
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
+KLQ + ++++ ++ K K+ L ++ E ESE ++ K
Sbjct: 291 QKLQTALAIAENNVQVLQKQLDDAKEGEMA-LLSKHKEVESELAAARERLQQQASDLVLK 349
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+ + +A+ E+ ++K L + + + + + QLE+ + ++ ++L+E E
Sbjct: 350 ASHI--GMLQATQMTQEV-TIKDLESEKSRVNE-RLSQLEEERAFLRSKTQSLDE---EQ 402
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK 728
++E E+K+ AK+ + Y +E+K + + E Q + S+ ++A
Sbjct: 403 KQQILELEKKVNEAKRTQQEY-----YERELKNLQSRLEEEVTQLNEAHSKTLEELAWKH 457
Query: 729 QVDFKQKIST-LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ + S +R++ K HNK L E K + ++EL N ++ ++D +N
Sbjct: 458 HMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQ 517
Query: 788 K-KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ LQ I L+ + +E+++ + ++ + + L E A +
Sbjct: 518 EIGHLQDMVRKSEQGLGSAEGLIASLQDS-QERLQNELDLTKDS--LKETKDALL----- 569
Query: 847 AFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N L+ E QQH++ +E EK++ DK+ + T+ L ++ L++E+
Sbjct: 570 --NVEGELEQERQQHEETIAAMKEEEKLKV--DKMAHDLEIKWTEN--LRQECSKLREEL 623
Query: 906 AKQ--EVYKRDLDDNLCLRKAQTDIT--NWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
Q E K + L L+ + + +WQK+ ++L LN I+ + N + L QT
Sbjct: 624 RLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDL---LNQISLLKQNLEIQLSQSQT 680
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELE---KSLSKDIEKKFREKMYELH-VTKAIDKDI 1017
L Q +A+ T L + L+ + + KSL + F+ E +A++ +
Sbjct: 681 SLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 740
Query: 1018 REYAVALDKCLMEFHREKMENINM 1041
++ A + L + HRE ME +
Sbjct: 741 QQKHSAELQSLKDAHRESMEGFRI 764
Score = 42.3 bits (95), Expect = 0.010
Identities = 74/400 (18%), Positives = 173/400 (43%), Gaps = 32/400 (8%)
Query: 617 QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD-TQIKTLNETVEEITMSLIEP 675
+R S ++E ++S + + + +I +LEK++ + TQ + ++ + L
Sbjct: 379 ERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRL--- 435
Query: 676 EQKMTTAKQIHGDM--PMLDRYIQEIKTV-TKKFEAVKEQCGDVDSEMTLDVATAKQVDF 732
E+++T + H + ++ I+ V + K+ D++ + D ++ D
Sbjct: 436 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEE-DK 494
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQ 792
Q L N + + KLN N+++ L + K+++ L + + I +L++S+++LQ
Sbjct: 495 NQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGL---IASLQDSQERLQ 551
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
++ A+ +E L+++ + E + ++ + +A ++ +
Sbjct: 552 NELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAH-DLEIKWTE 610
Query: 853 SLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA--KQE 909
+L E + +++ + E +K + L K ++ R KK++ L ++I+ KQ
Sbjct: 611 NLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQN 670
Query: 910 VYKRDLDDNLCLRKAQTDITNWQK----QDDELNEKLNGINK-------------EELNE 952
+ + L++ Q T ++ + +EL E+ +K EE E
Sbjct: 671 LEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKE 730
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
KE ++ + AE ++S++GFR E+E+ L
Sbjct: 731 KEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 770
Score = 33.1 bits (72), Expect = 6.2
Identities = 29/154 (18%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 189 DCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN-- 246
D +RL+ +LK ++ V+ + ++ +++ + KEEEK+ +K ++
Sbjct: 545 DSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDL 604
Query: 247 EIEYNKFILLE-SQNQEKIDKRNEQIVETA--KIAEIENITEVQTNEEAENATKTILEKV 303
EI++ + + E S+ +E++ ++E+ ++A ++ ++++ + + + + +L ++
Sbjct: 605 EIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQI 664
Query: 304 ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
LK + ++Q SQ+ ++ Q + R TQ
Sbjct: 665 SLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQ 698
>AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 57.6 bits (133), Expect = 3e-07
Identities = 105/504 (20%), Positives = 219/504 (43%), Gaps = 41/504 (8%)
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
+KLQ + ++++ ++ K K+ L ++ E ESE ++ K
Sbjct: 324 QKLQTALAIAENNVQVLQKQLDDAKEGEMA-LLSKHKEVESELAAARERLQQQASDLVLK 382
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+ + +A+ E+ ++K L + + + + + QLE+ + ++ ++L+E E
Sbjct: 383 ASHI--GMLQATQMTQEV-TIKDLESEKSRVNE-RLSQLEEERAFLRSKTQSLDE---EQ 435
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK 728
++E E+K+ AK+ + Y +E+K + + E Q + S+ ++A
Sbjct: 436 KQQILELEKKVNEAKRTQQEY-----YERELKNLQSRLEEEVTQLNEAHSKTLEELAWKH 490
Query: 729 QVDFKQKIST-LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ + S +R++ K HNK L E K + ++EL N ++ ++D +N
Sbjct: 491 HMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQ 550
Query: 788 K-KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ LQ I L+ + +E+++ + ++ + + L E A +
Sbjct: 551 EIGHLQDMVRKSEQGLGSAEGLIASLQDS-QERLQNELDLTKDS--LKETKDALL----- 602
Query: 847 AFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N L+ E QQH++ +E EK++ DK+ + T+ L ++ L++E+
Sbjct: 603 --NVEGELEQERQQHEETIAAMKEEEKLKV--DKMAHDLEIKWTEN--LRQECSKLREEL 656
Query: 906 AKQ--EVYKRDLDDNLCLRKAQTDIT--NWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
Q E K + L L+ + + +WQK+ ++L LN I+ + N + L QT
Sbjct: 657 RLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDL---LNQISLLKQNLEIQLSQSQT 713
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELE---KSLSKDIEKKFREKMYELH-VTKAIDKDI 1017
L Q +A+ T L + L+ + + KSL + F+ E +A++ +
Sbjct: 714 SLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 773
Query: 1018 REYAVALDKCLMEFHREKMENINM 1041
++ A + L + HRE ME +
Sbjct: 774 QQKHSAELQSLKDAHRESMEGFRI 797
Score = 42.3 bits (95), Expect = 0.010
Identities = 74/400 (18%), Positives = 173/400 (43%), Gaps = 32/400 (8%)
Query: 617 QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD-TQIKTLNETVEEITMSLIEP 675
+R S ++E ++S + + + +I +LEK++ + TQ + ++ + L
Sbjct: 412 ERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRL--- 468
Query: 676 EQKMTTAKQIHGDM--PMLDRYIQEIKTV-TKKFEAVKEQCGDVDSEMTLDVATAKQVDF 732
E+++T + H + ++ I+ V + K+ D++ + D ++ D
Sbjct: 469 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEE-DK 527
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQ 792
Q L N + + KLN N+++ L + K+++ L + + I +L++S+++LQ
Sbjct: 528 NQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGL---IASLQDSQERLQ 584
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
++ A+ +E L+++ + E + ++ + +A ++ +
Sbjct: 585 NELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAH-DLEIKWTE 643
Query: 853 SLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA--KQE 909
+L E + +++ + E +K + L K ++ R KK++ L ++I+ KQ
Sbjct: 644 NLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQN 703
Query: 910 VYKRDLDDNLCLRKAQTDITNWQK----QDDELNEKLNGINK-------------EELNE 952
+ + L++ Q T ++ + +EL E+ +K EE E
Sbjct: 704 LEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKE 763
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
KE ++ + AE ++S++GFR E+E+ L
Sbjct: 764 KEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 803
Score = 33.1 bits (72), Expect = 6.2
Identities = 29/154 (18%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 189 DCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN-- 246
D +RL+ +LK ++ V+ + ++ +++ + KEEEK+ +K ++
Sbjct: 578 DSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDL 637
Query: 247 EIEYNKFILLE-SQNQEKIDKRNEQIVETA--KIAEIENITEVQTNEEAENATKTILEKV 303
EI++ + + E S+ +E++ ++E+ ++A ++ ++++ + + + + +L ++
Sbjct: 638 EIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQI 697
Query: 304 ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
LK + ++Q SQ+ ++ Q + R TQ
Sbjct: 698 SLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQ 731
>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
Length = 1710
Score = 57.6 bits (133), Expect = 3e-07
Identities = 161/820 (19%), Positives = 319/820 (38%), Gaps = 60/820 (7%)
Query: 187 YSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
Y ++L++ + Y + +++ + +++ + EL + K N + +E A + S
Sbjct: 809 YEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELR-TVKSNLNQVVQERNDAQRQLSR 867
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E N +L + + K+ E I K EN + ++ + + E++ L
Sbjct: 868 E--QNARMLQDGILTNHLSKQKE-IEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAML 924
Query: 307 KSDHKVQKSQADEEEKKA---QGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSA 363
+ + K+Q E+EKK V E + +T+
Sbjct: 925 RLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAE 984
Query: 364 NQSXXXXXXXXXXXXXXXXXHKQAENE---LNIEECQQEINEDEKAVEQYEQEMDELSQK 420
N ++ + I + Q + +++ DE S+
Sbjct: 985 NAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRL 1044
Query: 421 ITKLQKQTAKLKEK-EMIEENLKTKEKQLIVLKNK-HKT--ALME-LLG-NVPEKDFAVT 474
K+ + LK+ E++ + L E +L L+ + H T AL E LG +KD + T
Sbjct: 1045 QDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQT 1104
Query: 475 ---INKFECEVRNE---VXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI 528
+ + E + +NE V L++E +R+ L++ + KA++K
Sbjct: 1105 QCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHN---KADNKE 1161
Query: 529 YKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENE 588
Q ++ V+KLQ E + S+ + + K + + C L R ++ E
Sbjct: 1162 KTVINIQ------DQFHAIVQKLQAESE--KQSLLLEERNKELISE--CNHLKERQYQYE 1211
Query: 589 SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN-EKITTLKDTEIPQL 647
+E + L+K + + AS E+ S +N E T ++ Q+
Sbjct: 1212 NEKAEREVVVRQLQQELADTLKK--QSMSEASL---EVTSRYRINLEDETQDLKKKLGQI 1266
Query: 648 EKRIVDVD---TQIKTLNETVEEITMSLIEPEQKM-TTAKQIHGDMPMLDRYIQEIKTVT 703
++ + T+ E +++ L + K+ T K+ + L + +
Sbjct: 1267 RNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSE 1326
Query: 704 KKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAH-NKKLQTLY 761
+ E +K+ S E LD K V+ +++I+ +N +K T+KKLN + N +
Sbjct: 1327 DEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHG 1386
Query: 762 EKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE 821
+ KT E + K I +L + S C + ++ K+ +
Sbjct: 1387 DLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEK 1446
Query: 822 AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLM 881
+ + +++I S +I + V +VK EI++ ++ + EK++E N L
Sbjct: 1447 LQKNKKKLEQEVINLRS-HIERNMVELGQVKQYKQEIEERARQEI---AEKLKEVNLFLQ 1502
Query: 882 EKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK 941
+ Q ++K ++ E+ +DL+ L K +T ++ K EL EK
Sbjct: 1503 AQAASQENLEQFRENNFASMKSQM---ELRIKDLESE--LSKIKTSQEDFNK--TEL-EK 1554
Query: 942 LNGINKEELNEKESLIIKQTKLFQQKAEC-TGALSELKKS 980
+ EEL ++SL K TK ++ AE T L E ++S
Sbjct: 1555 YKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQS 1594
Score = 37.9 bits (84), Expect = 0.22
Identities = 84/500 (16%), Positives = 209/500 (41%), Gaps = 48/500 (9%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
+E E N ++ QYE E E + +LQ++ A LK++ M E +L+ + I L+
Sbjct: 1194 KELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLE 1253
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
++ + L + LG + N+ + E ++ LE + ++
Sbjct: 1254 DETQD-LKKKLGQIR--------NQLQ-EAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKV 1303
Query: 513 SLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQ-DEQNVLQSSMFI---INKY 568
++ ++ ++ + + + A ++ L K + L+ + ++ ++ + I +
Sbjct: 1304 TVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGF 1363
Query: 569 KGQLK--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK---- 622
K LK N F + + K++ +T +L+ A +K
Sbjct: 1364 KNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHL 1423
Query: 623 -------KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
++E+LSMK++ +K L+ + +LE+ ++++ + I+ + ++ E
Sbjct: 1424 DTKNQILQEELLSMKTVQKKCEKLQKNK-KKLEQEVINLRSHIERNMVELGQVKQYKQEI 1482
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ-CGDVDSEMTLDVATAKQVDFKQ 734
E++ ++I + ++ ++Q + E +E + S+M L + D +
Sbjct: 1483 EER--ARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIK-----DLES 1535
Query: 735 KISTLRNRVKTTQKKLNAHN-KKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQS 793
++S ++KT+Q+ N +K + LY ++ K ++ L + K + + +K ++
Sbjct: 1536 ELS----KIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEK 1591
Query: 794 DCXXXXXXXXXXXXAITPLEVA-LKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
+ P V L ++ +++ R +I + + N ++
Sbjct: 1592 QQSRSLFTTLTTRPVMEPPCVGNLNNSLDLNRKLIPRENLVISTSNPRASN-----NSME 1646
Query: 853 SLDAEIQQHKKKNVPREMEK 872
+ +++QQ +KN+ RE+++
Sbjct: 1647 NYLSKMQQELEKNITRELKE 1666
Score = 35.9 bits (79), Expect = 0.88
Identities = 57/291 (19%), Positives = 132/291 (45%), Gaps = 33/291 (11%)
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
++V++++++ +LR + ++K + TLYEK +E+L +++ + V E
Sbjct: 780 QKVEWERELCSLRFSLNQEEEK----RRNADTLYEK---IREQLRRKEEQYRKEV---EV 829
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR-RNRDLIEAGSAYIAKVEV 846
K+QL+ + L ++E+ +A+ ++ R +N +++ G +
Sbjct: 830 KQQLELSLQTLEMELRTVK---SNLNQVVQERNDAQRQLSREQNARMLQDG--------I 878
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
N + S EI+ +KK +E D L K + + +L +IDT+K++
Sbjct: 879 LTNHL-SKQKEIEMAQKKMNSENSHSHEEEKD-LSHKNSMLQEEIAMLRLEIDTIKNQ-- 934
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDE-LNEKLNGINKEELNEKESLIIKQTKLFQ 965
QE K+ +D +++ D+ KQ++E L + ++ + N + S++ + +
Sbjct: 935 NQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTIS-----QYNGRLSVLTAENAMLN 989
Query: 966 QKAECTGALSE-LKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
K E E L+ ++ + + L ++ + + ++ EL +A D+
Sbjct: 990 SKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDE 1040
>AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 57.6 bits (133), Expect = 3e-07
Identities = 105/504 (20%), Positives = 219/504 (43%), Gaps = 41/504 (8%)
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
+KLQ + ++++ ++ K K+ L ++ E ESE ++ K
Sbjct: 324 QKLQTALAIAENNVQVLQKQLDDAKEGEMA-LLSKHKEVESELAAARERLQQQASDLVLK 382
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+ + +A+ E+ ++K L + + + + + QLE+ + ++ ++L+E E
Sbjct: 383 ASHI--GMLQATQMTQEV-TIKDLESEKSRVNE-RLSQLEEERAFLRSKTQSLDE---EQ 435
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK 728
++E E+K+ AK+ + Y +E+K + + E Q + S+ ++A
Sbjct: 436 KQQILELEKKVNEAKRTQQEY-----YERELKNLQSRLEEEVTQLNEAHSKTLEELAWKH 490
Query: 729 QVDFKQKIST-LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ + S +R++ K HNK L E K + ++EL N ++ ++D +N
Sbjct: 491 HMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQ 550
Query: 788 K-KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ LQ I L+ + +E+++ + ++ + + L E A +
Sbjct: 551 EIGHLQDMVRKSEQGLGSAEGLIASLQDS-QERLQNELDLTKDS--LKETKDALL----- 602
Query: 847 AFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N L+ E QQH++ +E EK++ DK+ + T+ L ++ L++E+
Sbjct: 603 --NVEGELEQERQQHEETIAAMKEEEKLKV--DKMAHDLEIKWTEN--LRQECSKLREEL 656
Query: 906 AKQ--EVYKRDLDDNLCLRKAQTDIT--NWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
Q E K + L L+ + + +WQK+ ++L LN I+ + N + L QT
Sbjct: 657 RLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDL---LNQISLLKQNLEIQLSQSQT 713
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELE---KSLSKDIEKKFREKMYELH-VTKAIDKDI 1017
L Q +A+ T L + L+ + + KSL + F+ E +A++ +
Sbjct: 714 SLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 773
Query: 1018 REYAVALDKCLMEFHREKMENINM 1041
++ A + L + HRE ME +
Sbjct: 774 QQKHSAELQSLKDAHRESMEGFRI 797
Score = 42.3 bits (95), Expect = 0.010
Identities = 74/400 (18%), Positives = 173/400 (43%), Gaps = 32/400 (8%)
Query: 617 QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD-TQIKTLNETVEEITMSLIEP 675
+R S ++E ++S + + + +I +LEK++ + TQ + ++ + L
Sbjct: 412 ERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRL--- 468
Query: 676 EQKMTTAKQIHGDM--PMLDRYIQEIKTV-TKKFEAVKEQCGDVDSEMTLDVATAKQVDF 732
E+++T + H + ++ I+ V + K+ D++ + D ++ D
Sbjct: 469 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEE-DK 527
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQ 792
Q L N + + KLN N+++ L + K+++ L + + I +L++S+++LQ
Sbjct: 528 NQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGL---IASLQDSQERLQ 584
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
++ A+ +E L+++ + E + ++ + +A ++ +
Sbjct: 585 NELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAH-DLEIKWTE 643
Query: 853 SLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA--KQE 909
+L E + +++ + E +K + L K ++ R KK++ L ++I+ KQ
Sbjct: 644 NLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQN 703
Query: 910 VYKRDLDDNLCLRKAQTDITNWQK----QDDELNEKLNGINK-------------EELNE 952
+ + L++ Q T ++ + +EL E+ +K EE E
Sbjct: 704 LEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKE 763
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
KE ++ + AE ++S++GFR E+E+ L
Sbjct: 764 KEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 803
Score = 33.1 bits (72), Expect = 6.2
Identities = 29/154 (18%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 189 DCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN-- 246
D +RL+ +LK ++ V+ + ++ +++ + KEEEK+ +K ++
Sbjct: 578 DSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDL 637
Query: 247 EIEYNKFILLE-SQNQEKIDKRNEQIVETA--KIAEIENITEVQTNEEAENATKTILEKV 303
EI++ + + E S+ +E++ ++E+ ++A ++ ++++ + + + + +L ++
Sbjct: 638 EIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQI 697
Query: 304 ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
LK + ++Q SQ+ ++ Q + R TQ
Sbjct: 698 SLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQ 731
>AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open reading
frame 60 protein.
Length = 1140
Score = 57.6 bits (133), Expect = 3e-07
Identities = 105/504 (20%), Positives = 219/504 (43%), Gaps = 41/504 (8%)
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
+KLQ + ++++ ++ K K+ L ++ E ESE ++ K
Sbjct: 324 QKLQTALAIAENNVQVLQKQLDDAKEGEMA-LLSKHKEVESELAAARERLQQQASDLVLK 382
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+ + +A+ E+ ++K L + + + + + QLE+ + ++ ++L+E E
Sbjct: 383 ASHI--GMLQATQMTQEV-TIKDLESEKSRVNE-RLSQLEEERAFLRSKTQSLDE---EQ 435
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK 728
++E E+K+ AK+ + Y +E+K + + E Q + S+ ++A
Sbjct: 436 KQQILELEKKVNEAKRTQQEY-----YERELKNLQSRLEEEVTQLNEAHSKTLEELAWKH 490
Query: 729 QVDFKQKIST-LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ + S +R++ K HNK L E K + ++EL N ++ ++D +N
Sbjct: 491 HMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQ 550
Query: 788 K-KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ LQ I L+ + +E+++ + ++ + + L E A +
Sbjct: 551 EIGHLQDMVRKSEQGLGSAEGLIASLQDS-QERLQNELDLTKDS--LKETKDALL----- 602
Query: 847 AFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N L+ E QQH++ +E EK++ DK+ + T+ L ++ L++E+
Sbjct: 603 --NVEGELEQERQQHEETIAAMKEEEKLKV--DKMAHDLEIKWTEN--LRQECSKLREEL 656
Query: 906 AKQ--EVYKRDLDDNLCLRKAQTDIT--NWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
Q E K + L L+ + + +WQK+ ++L LN I+ + N + L QT
Sbjct: 657 RLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDL---LNQISLLKQNLEIQLSQSQT 713
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELE---KSLSKDIEKKFREKMYELH-VTKAIDKDI 1017
L Q +A+ T L + L+ + + KSL + F+ E +A++ +
Sbjct: 714 SLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 773
Query: 1018 REYAVALDKCLMEFHREKMENINM 1041
++ A + L + HRE ME +
Sbjct: 774 QQKHSAELQSLKDAHRESMEGFRI 797
Score = 42.3 bits (95), Expect = 0.010
Identities = 74/400 (18%), Positives = 173/400 (43%), Gaps = 32/400 (8%)
Query: 617 QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD-TQIKTLNETVEEITMSLIEP 675
+R S ++E ++S + + + +I +LEK++ + TQ + ++ + L
Sbjct: 412 ERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRL--- 468
Query: 676 EQKMTTAKQIHGDM--PMLDRYIQEIKTV-TKKFEAVKEQCGDVDSEMTLDVATAKQVDF 732
E+++T + H + ++ I+ V + K+ D++ + D ++ D
Sbjct: 469 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEE-DK 527
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQ 792
Q L N + + KLN N+++ L + K+++ L + + I +L++S+++LQ
Sbjct: 528 NQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGL---IASLQDSQERLQ 584
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
++ A+ +E L+++ + E + ++ + +A ++ +
Sbjct: 585 NELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAH-DLEIKWTE 643
Query: 853 SLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA--KQE 909
+L E + +++ + E +K + L K ++ R KK++ L ++I+ KQ
Sbjct: 644 NLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQN 703
Query: 910 VYKRDLDDNLCLRKAQTDITNWQK----QDDELNEKLNGINK-------------EELNE 952
+ + L++ Q T ++ + +EL E+ +K EE E
Sbjct: 704 LEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKE 763
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
KE ++ + AE ++S++GFR E+E+ L
Sbjct: 764 KEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 803
Score = 33.1 bits (72), Expect = 6.2
Identities = 29/154 (18%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 189 DCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN-- 246
D +RL+ +LK ++ V+ + ++ +++ + KEEEK+ +K ++
Sbjct: 578 DSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDL 637
Query: 247 EIEYNKFILLE-SQNQEKIDKRNEQIVETA--KIAEIENITEVQTNEEAENATKTILEKV 303
EI++ + + E S+ +E++ ++E+ ++A ++ ++++ + + + + +L ++
Sbjct: 638 EIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQI 697
Query: 304 ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
LK + ++Q SQ+ ++ Q + R TQ
Sbjct: 698 SLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQ 731
>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
Length = 1715
Score = 57.6 bits (133), Expect = 3e-07
Identities = 161/820 (19%), Positives = 319/820 (38%), Gaps = 60/820 (7%)
Query: 187 YSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
Y ++L++ + Y + +++ + +++ + EL + K N + +E A + S
Sbjct: 814 YEKIREQLRRKEEQYRKEVEVKQQLELSLQTLEMELR-TVKSNLNQVVQERNDAQRQLSR 872
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E N +L + + K+ E I K EN + ++ + + E++ L
Sbjct: 873 E--QNARMLQDGILTNHLSKQKE-IEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAML 929
Query: 307 KSDHKVQKSQADEEEKKA---QGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSA 363
+ + K+Q E+EKK V E + +T+
Sbjct: 930 RLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAE 989
Query: 364 NQSXXXXXXXXXXXXXXXXXHKQAENE---LNIEECQQEINEDEKAVEQYEQEMDELSQK 420
N ++ + I + Q + +++ DE S+
Sbjct: 990 NAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRL 1049
Query: 421 ITKLQKQTAKLKEK-EMIEENLKTKEKQLIVLKNK-HKT--ALME-LLG-NVPEKDFAVT 474
K+ + LK+ E++ + L E +L L+ + H T AL E LG +KD + T
Sbjct: 1050 QDKMNFDVSNLKDNNEILSQQLFKTESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQT 1109
Query: 475 ---INKFECEVRNE---VXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKI 528
+ + E + +NE V L++E +R+ L++ + KA++K
Sbjct: 1110 QCQMKEMEQKYQNEQVKVNKYIGKQESVEERLSQLQSENMLLRQQLDDAHN---KADNKE 1166
Query: 529 YKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENE 588
Q ++ V+KLQ E + S+ + + K + + C L R ++ E
Sbjct: 1167 KTVINIQ------DQFHAIVQKLQAESE--KQSLLLEERNKELISE--CNHLKERQYQYE 1216
Query: 589 SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLN-EKITTLKDTEIPQL 647
+E + L+K + + AS E+ S +N E T ++ Q+
Sbjct: 1217 NEKAEREVVVRQLQQELADTLKK--QSMSEASL---EVTSRYRINLEDETQDLKKKLGQI 1271
Query: 648 EKRIVDVD---TQIKTLNETVEEITMSLIEPEQKM-TTAKQIHGDMPMLDRYIQEIKTVT 703
++ + T+ E +++ L + K+ T K+ + L + +
Sbjct: 1272 RNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQKNLLNANLSE 1331
Query: 704 KKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAH-NKKLQTLY 761
+ E +K+ S E LD K V+ +++I+ +N +K T+KKLN + N +
Sbjct: 1332 DEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEYENGEFSFHG 1391
Query: 762 EKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIE 821
+ KT E + K I +L + S C + ++ K+ +
Sbjct: 1392 DLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQEELLSMKTVQKKCEK 1451
Query: 822 AKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLM 881
+ + +++I S +I + V +VK EI++ ++ + EK++E N L
Sbjct: 1452 LQKNKKKLEQEVINLRS-HIERNMVELGQVKQYKQEIEERARQEI---AEKLKEVNLFLQ 1507
Query: 882 EKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK 941
+ Q ++K ++ E+ +DL+ L K +T ++ K EL EK
Sbjct: 1508 AQAASQENLEQFRENNFASMKSQM---ELRIKDLESE--LSKIKTSQEDFNK--TEL-EK 1559
Query: 942 LNGINKEELNEKESLIIKQTKLFQQKAEC-TGALSELKKS 980
+ EEL ++SL K TK ++ AE T L E ++S
Sbjct: 1560 YKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEKQQS 1599
Score = 37.9 bits (84), Expect = 0.22
Identities = 84/500 (16%), Positives = 209/500 (41%), Gaps = 48/500 (9%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
+E E N ++ QYE E E + +LQ++ A LK++ M E +L+ + I L+
Sbjct: 1199 KELISECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLE 1258
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
++ + L + LG + N+ + E ++ LE + ++
Sbjct: 1259 DETQD-LKKKLGQIR--------NQLQ-EAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKV 1308
Query: 513 SLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQ-DEQNVLQSSMFI---INKY 568
++ ++ ++ + + + A ++ L K + L+ + ++ ++ + I +
Sbjct: 1309 TVKKQMDKIEELQKNLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGF 1368
Query: 569 KGQLK--DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK---- 622
K LK N F + + K++ +T +L+ A +K
Sbjct: 1369 KNLLKMTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHL 1428
Query: 623 -------KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
++E+LSMK++ +K L+ + +LE+ ++++ + I+ + ++ E
Sbjct: 1429 DTKNQILQEELLSMKTVQKKCEKLQKNK-KKLEQEVINLRSHIERNMVELGQVKQYKQEI 1487
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ-CGDVDSEMTLDVATAKQVDFKQ 734
E++ ++I + ++ ++Q + E +E + S+M L + D +
Sbjct: 1488 EER--ARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIK-----DLES 1540
Query: 735 KISTLRNRVKTTQKKLNAHN-KKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQS 793
++S ++KT+Q+ N +K + LY ++ K ++ L + K + + +K ++
Sbjct: 1541 ELS----KIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKLLVEK 1596
Query: 794 DCXXXXXXXXXXXXAITPLEVA-LKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
+ P V L ++ +++ R +I + + N ++
Sbjct: 1597 QQSRSLFTTLTTRPVMEPPCVGNLNNSLDLNRKLIPRENLVISTSNPRASN-----NSME 1651
Query: 853 SLDAEIQQHKKKNVPREMEK 872
+ +++QQ +KN+ RE+++
Sbjct: 1652 NYLSKMQQELEKNITRELKE 1671
Score = 35.9 bits (79), Expect = 0.88
Identities = 57/291 (19%), Positives = 132/291 (45%), Gaps = 33/291 (11%)
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
++V++++++ +LR + ++K + TLYEK +E+L +++ + V E
Sbjct: 785 QKVEWERELCSLRFSLNQEEEK----RRNADTLYEK---IREQLRRKEEQYRKEV---EV 834
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR-RNRDLIEAGSAYIAKVEV 846
K+QL+ + L ++E+ +A+ ++ R +N +++ G +
Sbjct: 835 KQQLELSLQTLEMELRTVK---SNLNQVVQERNDAQRQLSREQNARMLQDG--------I 883
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
N + S EI+ +KK +E D L K + + +L +IDT+K++
Sbjct: 884 LTNHL-SKQKEIEMAQKKMNSENSHSHEEEKD-LSHKNSMLQEEIAMLRLEIDTIKNQ-- 939
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDE-LNEKLNGINKEELNEKESLIIKQTKLFQ 965
QE K+ +D +++ D+ KQ++E L + ++ + N + S++ + +
Sbjct: 940 NQEKEKKCFEDLKIVKEKNEDLQKTIKQNEETLTQTIS-----QYNGRLSVLTAENAMLN 994
Query: 966 QKAECTGALSE-LKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
K E E L+ ++ + + L ++ + + ++ EL +A D+
Sbjct: 995 SKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDE 1045
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 57.2 bits (132), Expect = 3e-07
Identities = 86/462 (18%), Positives = 203/462 (43%), Gaps = 38/462 (8%)
Query: 611 KVTEDLQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVE 666
++ +L++ K D++L+ K+++ K +D E + E + + + ++ E E
Sbjct: 350 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 409
Query: 667 EIT----MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E+ M E E +++ + ++ L++ + ++T ++ + E+ D + + T
Sbjct: 410 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATE 468
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
D +V+ + ++ ++ ++LQ L+E +T+ ++E
Sbjct: 469 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK 528
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
LE K L+ + L+ +K+ + + E R +RD I A +
Sbjct: 529 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKD-FQRELEDARASRDEIFATAKEN 587
Query: 842 AKVEVAFNKVKSLDAEIQQ---------HKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ 892
K K KSL+A++ Q +K E E++ E + + + +++
Sbjct: 588 EK------KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR 641
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
L +I L++E+ +++ + D + RKA ++ +EL + + K E +
Sbjct: 642 RLEARIAQLEEELEEEQGNMEAMSDRV--RKATQQA---EQLSNELATERSTAQKNESSR 696
Query: 953 KESLIIKQTKLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVT 1010
++ + +Q K + K E GA+ S+ K ++ ++ + L + +E++ REK
Sbjct: 697 QQ--LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSL 753
Query: 1011 KAIDKDIREYAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
K DK ++E + + ++ + E ++E+ E N +++L R++
Sbjct: 754 KQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 795
Score = 50.4 bits (115), Expect = 4e-05
Identities = 137/822 (16%), Positives = 317/822 (38%), Gaps = 62/822 (7%)
Query: 92 KQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKA 151
+ L+ R+ + A +K+ + L++ + +++ T D ++ +L +E+ V K
Sbjct: 34 EDLDSERAARNKAEKQKRDLGEELEALKTELED---TLDSTATQQELRAKREQEVTVLKK 90
Query: 152 ILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC-LDR----LKKIRKDYAQNLK 206
L+ H+ + + E E + K + LD+ L+K D A L+
Sbjct: 91 ALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 150
Query: 207 LLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE------KSSNEIEYNKFILLESQN 260
+L V+ K+K+LE ++ S + E+ E K NE+E +L E++
Sbjct: 151 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEG 210
Query: 261 QEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEE 320
+ I + ++++ + + + + +T ++ +TK + L+ + + Q DEE
Sbjct: 211 KA-IKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK-----LRQLEEERNSLQDQLDEE 264
Query: 321 EKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXX 380
+ Q + + Q +
Sbjct: 265 MEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAY 324
Query: 381 XXXHKQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLK-EKEMIE 438
K + +++ +++ + V E++ + Q + + + ++K E++ E
Sbjct: 325 DKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAE 384
Query: 439 ENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXX 497
+ KE + + L AL E L E + + K E E + +
Sbjct: 385 AEAREKETKALSLAR----ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELE 440
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAED-KIYKACGTQPYDVTLSK-YTTTVEKLQDEQ 555
LE + + ++ L E EL ED K+ Q + E+ ++++
Sbjct: 441 KSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKR 500
Query: 556 NVLQSSMFIIN-KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX----XMNVPGKLE 610
LQ + + + + K + + E + + + KL+
Sbjct: 501 RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQ 560
Query: 611 KVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+D QR A A +DEI + NEK + ++ QL++ + + K + E
Sbjct: 561 AQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKE 620
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVA 725
E+ L A + G + D + + + E ++E+ G++++ + A
Sbjct: 621 ELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 671
Query: 726 TAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
T + +++T R+ + ++++++L NK+L++ L+E + K + +T I
Sbjct: 672 TQQAEQLSNELATERSTAQKNESSRQQLERQNKELRSKLHEMEGAVKSKFKST------I 725
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGS 838
LE QL+ ++ + LKE ++E + ++ + ++ E G+
Sbjct: 726 AALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGN 785
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 786 ARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 826
Score = 42.7 bits (96), Expect = 0.008
Identities = 71/439 (16%), Positives = 180/439 (41%), Gaps = 25/439 (5%)
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+E++TE L++ K + K EK E+ L + +V+ + K L V+E+
Sbjct: 114 VEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQEL 173
Query: 669 TMSLIEPEQKMTTAK----QIHGDMPMLDRYIQEIK-TVTKKFEAVKEQCGDV-DSEMTL 722
+ E+ ++ ++ + + E + K + V + D++ L
Sbjct: 174 QSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELL 233
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
T ++++ K+ L + Q +L+ + Q L + +L +++KK+QD
Sbjct: 234 QEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFA 293
Query: 783 N----LEESKKQLQSDCXXXXXXXXXXXXAITPLEVA---LKEKIEAKTEVVRRNRDLIE 835
+ LEE KK+ Q + A LE L+++++ + R L+
Sbjct: 294 STVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVS 353
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK------IQEANDKLMEKQKQIMT 889
K + + K++ ++ + + EK + A ++ +E ++++
Sbjct: 354 NLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELER 413
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
++L +++ L +K +V K + R +T + + Q +EL ++L +
Sbjct: 414 TNKMLKAEMEDLVS--SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAK 471
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
L + ++ + + F++ + +E K+ + + +L + ++E + +++
Sbjct: 472 LRLEVNMQALKGQ-FERDLQARDEQNEEKR--RQLQRQLHE-YETELEDERKQRALAAAA 527
Query: 1010 TKAIDKDIREYAVALDKCL 1028
K ++ D+++ + D +
Sbjct: 528 KKKLEGDLKDLELQADSAI 546
>L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein.
Length = 1300
Score = 57.2 bits (132), Expect = 3e-07
Identities = 113/543 (20%), Positives = 235/543 (43%), Gaps = 65/543 (11%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKL--QKQTAKLKEKEMIEEN--LKT 443
ENE ++ ++ + + +Q EQ + +L + K ++++ +++ ++++E+N LK
Sbjct: 526 ENE--VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 583
Query: 444 KEKQL---IVLKNKHKTALMELLGNVPEKDFAV--TINKFECEVRNEVXXXXXXXXXXXX 498
+ +Q I + EL + EKD + T + E R+ +
Sbjct: 584 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE-RDRLTSKEEELKDIQN 642
Query: 499 XXXXLEAERKHIRESLNERRS---ELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQ 555
L+AE + ++ NE+ + EL K + +Y V K E+LQ E
Sbjct: 643 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVY---------VKDDKIRLLEEQLQHEI 693
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
+ I+N LK + L + +E KL+ V E
Sbjct: 694 SNKMEEFKILNDQNKALK-SEVQKL--QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEEL 750
Query: 616 LQ----RASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS 671
L+ + + K++E+ ++++ N +T E+ L+ + D Q+ + VEE+
Sbjct: 751 LETGLIQVATKEEELNAIRTENSSLTK----EVQDLKAKQND---QV-SFASLVEELKKV 802
Query: 672 LIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
+ E + K+ + +++ ++ + + ++ + ++ +A+KE+ G+V E A+Q+
Sbjct: 803 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK------AQQL 856
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
K+ L+N +K ++++N ++ + E+K K +L NT K +QD+ ES K
Sbjct: 857 SITSKVQELQNLLKGKEEQMNT----MKAVLEEKEK---DLANTGKWLQDLQEENESLKA 909
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV---A 847
+ LE+ LKEK + E+ R L E S +K ++
Sbjct: 910 HVQEVAQHNLKEASSASQFEELEIVLKEK---ENELKRLEAMLKERESDLSSKTQLLQDV 966
Query: 848 FNKVKSLDAEIQQHKKKNVPR--EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
++ K ++I+Q K++N + +E + E++K+I L ++D+LKD +
Sbjct: 967 QDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEI----SGLWNELDSLKDAV 1022
Query: 906 AKQ 908
Q
Sbjct: 1023 EHQ 1025
Score = 50.0 bits (114), Expect = 5e-05
Identities = 116/677 (17%), Positives = 277/677 (40%), Gaps = 60/677 (8%)
Query: 388 ENELNIEECQQEIN--EDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKE 445
E E N+ + + ++ E ++ +++Q +++ +I L+++ L++ N + +
Sbjct: 384 EKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTN-QLES 442
Query: 446 KQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEA 505
KQ L NK + L+ + EK K + E EV EA
Sbjct: 443 KQSAEL-NKLRQDYARLVNELTEKT-----GKLQQE---EVQKKNAEQAATQLKVQLQEA 493
Query: 506 ERK--HIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMF 563
ER+ ++ + +R +E A+ + + +V S ++ + L +Q + Q M
Sbjct: 494 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQ-SLHSKLTDTLVSKQQLEQRLMQ 552
Query: 564 IINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKK 623
++ + ++ + + ++E + + E+L + A+K
Sbjct: 553 LMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEK 612
Query: 624 DEIL-----SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
D+ + S+ S +++T+ K+ E+ ++ + +++ L E + E E K
Sbjct: 613 DKQIKQTEDSLASERDRLTS-KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELE-K 670
Query: 679 MTTAKQIHGD-MPMLDRYIQ-EIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI 736
M + + D + +L+ +Q EI ++F+ + +Q + SE+ + K +
Sbjct: 671 MQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVV 730
Query: 737 STLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKE------ELLNTQKKVQDIVNLEESKK 789
+ ++ +KL + L+T L + TK +E E + K+VQD+ + +
Sbjct: 731 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQV 790
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
S I +E L+ K+ K + V+ + I+A I V++
Sbjct: 791 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQL 850
Query: 847 AFNKVKSLDAEIQQHK-----KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ S+ +++Q+ + K+ M+ + E +K + + + D Q + +
Sbjct: 851 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 910
Query: 902 KDEIAKQ--------------EVYKRDLDDNL-----CLRKAQTDITNWQKQDDELNEKL 942
E+A+ E+ ++ ++ L L++ ++D+++ + ++ ++
Sbjct: 911 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDE- 969
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
N + K ++ + + +Q F E +SE +K + G NEL+ SL +E + ++
Sbjct: 970 NKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELD-SLKDAVEHQRKK 1028
Query: 1003 KMYELHVTKAIDKDIRE 1019
+A++ + +E
Sbjct: 1029 NNERQQQVEAVELEAKE 1045
>D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein.
Length = 2067
Score = 57.2 bits (132), Expect = 3e-07
Identities = 101/479 (21%), Positives = 210/479 (43%), Gaps = 56/479 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILS-MKSLNEKITT-LKDTEIP---------QLEKRIVDVDT 656
+LE+ DLQ S + L +K +++T L+DT++ +LEK+ D+
Sbjct: 1419 QLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1478
Query: 657 QIKTLNETV--EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
++ +E E++ ++ E+ M A+ L+ +I T+K +++ +
Sbjct: 1479 ELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ-QLEEKDMDIAGFTQKVVSLEAELQ 1537
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D+ S+ + D A+ +V K+++ L +VK +++L+ +Q L + K + + E+
Sbjct: 1538 DISSQESKDEASLAKV--KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERM 1595
Query: 775 -QKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
Q +++ + +E ++ + C + +EV L+E+ E K +V+R R+L
Sbjct: 1596 RQTHSKEMESRDEEVEEARQSCQKK----------LKQMEVQLEEEYEDKQKVLREKREL 1645
Query: 834 IEAGSAYIA------------KVEVAFNKVKSLDAEIQ---QHKKKNVPREMEKIQEAND 878
E A ++ ++ + K+L A+ Q H K + P + E I + +
Sbjct: 1646 -EGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKN 1703
Query: 879 KLMEKQ---KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC-LRKAQTDITNWQKQ 934
+L E + + R+ + +I+ L +I K L++ L L++ + +I N ++
Sbjct: 1704 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1763
Query: 935 DDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE----- 989
D E +L +K + + + + L Q E EL++ L+ ++++E
Sbjct: 1764 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1823
Query: 990 ---KSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
KSL E K RE L + K + A L + + + E+ + I RE
Sbjct: 1824 MVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE 1882
Score = 38.7 bits (86), Expect = 0.12
Identities = 72/410 (17%), Positives = 172/410 (41%), Gaps = 35/410 (8%)
Query: 402 EDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEM-IEENLKTKEKQLIVLKNKHKTAL 459
E E+ + + +EM+ +++ + ++ K LK+ E+ +EE + K+K L K + + L
Sbjct: 1591 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE-KRELEGKL 1649
Query: 460 MELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRS 519
L V +DF + E +R ++ L+ RE + + ++
Sbjct: 1650 ATLSDQVNRRDF-----ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKN 1703
Query: 520 ELTKAEDKIYKAC-GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN--S 576
+L ++E A + +V + ++ + + L+ + + + K ++++
Sbjct: 1704 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1763
Query: 577 CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD------EILSMK 630
N + ++ +LE+ ++ Q K E L
Sbjct: 1764 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1823
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMP 690
+++ + + ++ +I +LE R+ TQ+K L E + L E +K+T + +
Sbjct: 1824 MVDKSLVSRQEAKIRELETRLEFERTQVKRL----ESLASRLKENMEKLTEERDQR--IA 1877
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
+R ++ K + ++ KE+ G++ + A+ K+ + + + +L ++ Q L
Sbjct: 1878 AENREKEQNKRLQRQLRDTKEEMGELARKEA--EASRKKHELEMDLESLEAANQSLQADL 1935
Query: 751 NAHNKKLQTLY-----EKKTKAKEELLNTQKKVQDIV-NLEESKKQLQSD 794
K++ L E ++ E+L+N+ +QD+V ++ K +L+ D
Sbjct: 1936 KLAFKRIGDLQAAIEDEMESDENEDLINS---LQDMVTKYQKRKNKLEGD 1982
>D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein.
Length = 1307
Score = 57.2 bits (132), Expect = 3e-07
Identities = 113/543 (20%), Positives = 235/543 (43%), Gaps = 65/543 (11%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKL--QKQTAKLKEKEMIEEN--LKT 443
ENE ++ ++ + + +Q EQ + +L + K ++++ +++ ++++E+N LK
Sbjct: 533 ENE--VQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQNEALKA 590
Query: 444 KEKQL---IVLKNKHKTALMELLGNVPEKDFAV--TINKFECEVRNEVXXXXXXXXXXXX 498
+ +Q I + EL + EKD + T + E R+ +
Sbjct: 591 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASE-RDRLTSKEEELKDIQN 649
Query: 499 XXXXLEAERKHIRESLNERRS---ELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQ 555
L+AE + ++ NE+ + EL K + +Y V K E+LQ E
Sbjct: 650 MNFLLKAEVQKLQALANEQAAAAHELEKMQQSVY---------VKDDKIRLLEEQLQHEI 700
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
+ I+N LK + L + +E KL+ V E
Sbjct: 701 SNKMEEFKILNDQNKALK-SEVQKL--QTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEEL 757
Query: 616 LQ----RASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS 671
L+ + + K++E+ ++++ N +T E+ L+ + D Q+ + VEE+
Sbjct: 758 LETGLIQVATKEEELNAIRTENSSLTK----EVQDLKAKQND---QV-SFASLVEELKKV 809
Query: 672 LIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
+ E + K+ + +++ ++ + + ++ + ++ +A+KE+ G+V E A+Q+
Sbjct: 810 IHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEK------AQQL 863
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
K+ L+N +K ++++N ++ + E+K K +L NT K +QD+ ES K
Sbjct: 864 SITSKVQELQNLLKGKEEQMNT----MKAVLEEKEK---DLANTGKWLQDLQEENESLKA 916
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV---A 847
+ LE+ LKEK + E+ R L E S +K ++
Sbjct: 917 HVQEVAQHNLKEASSASQFEELEIVLKEK---ENELKRLEAMLKERESDLSSKTQLLQDV 973
Query: 848 FNKVKSLDAEIQQHKKKNVPR--EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
++ K ++I+Q K++N + +E + E++K+I L ++D+LKD +
Sbjct: 974 QDENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEI----SGLWNELDSLKDAV 1029
Query: 906 AKQ 908
Q
Sbjct: 1030 EHQ 1032
Score = 50.0 bits (114), Expect = 5e-05
Identities = 116/677 (17%), Positives = 277/677 (40%), Gaps = 60/677 (8%)
Query: 388 ENELNIEECQQEIN--EDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKE 445
E E N+ + + ++ E ++ +++Q +++ +I L+++ L++ N + +
Sbjct: 391 EKEHNVFQNKIHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTN-QLES 449
Query: 446 KQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEA 505
KQ L NK + L+ + EK K + E EV EA
Sbjct: 450 KQSAEL-NKLRQDYARLVNELTEKT-----GKLQQE---EVQKKNAEQAATQLKVQLQEA 500
Query: 506 ERK--HIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMF 563
ER+ ++ + +R +E A+ + + +V S ++ + L +Q + Q M
Sbjct: 501 ERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQ-SLHSKLTDTLVSKQQLEQRLMQ 559
Query: 564 IINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKK 623
++ + ++ + + ++E + + E+L + A+K
Sbjct: 560 LMESEQKRVNKEESLQMQVQDILEQNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEK 619
Query: 624 DEIL-----SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
D+ + S+ S +++T+ K+ E+ ++ + +++ L E + E E K
Sbjct: 620 DKQIKQTEDSLASERDRLTS-KEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELE-K 677
Query: 679 MTTAKQIHGD-MPMLDRYIQ-EIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI 736
M + + D + +L+ +Q EI ++F+ + +Q + SE+ + K +
Sbjct: 678 MQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVV 737
Query: 737 STLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKE------ELLNTQKKVQDIVNLEESKK 789
+ ++ +KL + L+T L + TK +E E + K+VQD+ + +
Sbjct: 738 EQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQV 797
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
S I +E L+ K+ K + V+ + I+A I V++
Sbjct: 798 SFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQL 857
Query: 847 AFNKVKSLDAEIQQHK-----KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ S+ +++Q+ + K+ M+ + E +K + + + D Q + +
Sbjct: 858 EKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAH 917
Query: 902 KDEIAKQ--------------EVYKRDLDDNL-----CLRKAQTDITNWQKQDDELNEKL 942
E+A+ E+ ++ ++ L L++ ++D+++ + ++ ++
Sbjct: 918 VQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDE- 976
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
N + K ++ + + +Q F E +SE +K + G NEL+ SL +E + ++
Sbjct: 977 NKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELD-SLKDAVEHQRKK 1035
Query: 1003 KMYELHVTKAIDKDIRE 1019
+A++ + +E
Sbjct: 1036 NNERQQQVEAVELEAKE 1052
>AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit
SP-R210 alphaS protein.
Length = 1581
Score = 57.2 bits (132), Expect = 3e-07
Identities = 101/479 (21%), Positives = 210/479 (43%), Gaps = 56/479 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILS-MKSLNEKITT-LKDTEIP---------QLEKRIVDVDT 656
+LE+ DLQ S + L +K +++T L+DT++ +LEK+ D+
Sbjct: 948 QLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1007
Query: 657 QIKTLNETV--EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
++ +E E++ ++ E+ M A+ L+ +I T+K +++ +
Sbjct: 1008 ELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ-QLEEKDMDIAGFTQKVVSLEAELQ 1066
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D+ S+ + D A+ +V K+++ L +VK +++L+ +Q L + K + + E+
Sbjct: 1067 DISSQESKDEASLAKV--KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERM 1124
Query: 775 -QKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
Q +++ + +E ++ + C + +EV L+E+ E K +V+R R+L
Sbjct: 1125 RQTHSKEMESRDEEVEEARQSCQKK----------LKQMEVQLEEEYEDKQKVLREKREL 1174
Query: 834 IEAGSAYIA------------KVEVAFNKVKSLDAEIQ---QHKKKNVPREMEKIQEAND 878
E A ++ ++ + K+L A+ Q H K + P + E I + +
Sbjct: 1175 -EGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKN 1232
Query: 879 KLMEKQ---KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC-LRKAQTDITNWQKQ 934
+L E + + R+ + +I+ L +I K L++ L L++ + +I N ++
Sbjct: 1233 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1292
Query: 935 DDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE----- 989
D E +L +K + + + + L Q E EL++ L+ ++++E
Sbjct: 1293 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1352
Query: 990 ---KSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
KSL E K RE L + K + A L + + + E+ + I RE
Sbjct: 1353 MVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE 1411
Score = 41.5 bits (93), Expect = 0.018
Identities = 63/324 (19%), Positives = 136/324 (41%), Gaps = 22/324 (6%)
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQ 219
H E E +K + RFD ++L++ + +++ L E ++ + ++
Sbjct: 987 HLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEE 1046
Query: 220 KELEDS--YKKNTSFNKEEEKIANEKSSNEIEYNKFIL----LESQ---NQEKIDKR--N 268
K+++ + +K S E + I++++S +E K LE++ +E++D++
Sbjct: 1047 KDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGT 1106
Query: 269 EQIVETAKIA-EIENITEVQTN-EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQG 326
Q++E AK+ E+E QT+ +E E+ + + E +S + K + Q +EE + Q
Sbjct: 1107 IQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQK 1166
Query: 327 FVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHK- 385
+ E R + D+ +
Sbjct: 1167 VLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE 1226
Query: 386 --QAENELNIEE--CQQEINED---EKAVEQYEQEMDELSQKITKLQKQTAKL-KEKEMI 437
Q +N+L E C + E +E ++D++++ T L++Q ++L +EK I
Sbjct: 1227 IAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEI 1286
Query: 438 EENLKTKEKQLIVLKNKHKTALME 461
+ L+ ++ + L KHK A+ +
Sbjct: 1287 QNRLEEDQEDMNELMKKHKAAVAQ 1310
Score = 35.5 bits (78), Expect = 1.2
Identities = 66/390 (16%), Positives = 161/390 (41%), Gaps = 31/390 (7%)
Query: 402 EDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEM-IEENLKTKEKQLIVLKNKHKTAL 459
E E+ + + +EM+ +++ + ++ K LK+ E+ +EE + K+K L K + + L
Sbjct: 1120 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE-KRELEGKL 1178
Query: 460 MELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRS 519
L V +DF + E +R ++ L+ RE + + ++
Sbjct: 1179 ATLSDQVNRRDF-----ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKN 1232
Query: 520 ELTKAEDKIYKAC-GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN--S 576
+L ++E A + +V + ++ + + L+ + + + K ++++
Sbjct: 1233 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1292
Query: 577 CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD------EILSMK 630
N + ++ +LE+ ++ Q K E L
Sbjct: 1293 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1352
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMP 690
+++ + + ++ +I +LE R+ TQ+K L E + L E +K+T + +
Sbjct: 1353 MVDKSLVSRQEAKIRELETRLEFERTQVKRL----ESLASRLKENMEKLTEERDQR--IA 1406
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
+R ++ K + ++ KE+ G++ + A+ K+ + + + +L ++ Q L
Sbjct: 1407 AENREKEQNKRLQRQLRDTKEEMGELARKEA--EASRKKHELEMDLESLEAANQSLQADL 1464
Query: 751 NAHNKKLQTLY-----EKKTKAKEELLNTQ 775
K++ L E ++ E+L+N++
Sbjct: 1465 KLAFKRIGDLQAAIEDEMESDENEDLINSE 1494
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 57.2 bits (132), Expect = 3e-07
Identities = 132/723 (18%), Positives = 303/723 (41%), Gaps = 56/723 (7%)
Query: 386 QAENEL---NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLK 442
QAE E+ N+ C++E ++ Y+ E++ L +K+ +L+++ KEK I +
Sbjct: 267 QAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRI---MA 323
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
K +++ + + ++++L + KD + +KF N
Sbjct: 324 VKNSEVMAQLTESRQSILKLESELENKD-EILRDKFSLMNENRELKVRVAAQNERLDLCQ 382
Query: 503 LEAERKHIR-ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNV--LQ 559
E E + SL + S+L + G + Y LSKY + ++++ + +
Sbjct: 383 QEIESSRVELRSLEKIISQLPLKRELF----GFKSY---LSKYQMSSFSNKEDRCIGCCE 435
Query: 560 SSMFIIN--KYKGQLKDNSCCPL-CNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
++ +I+ + K +K+ L N S+ + E V
Sbjct: 436 ANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGG 495
Query: 617 QRASAKKDEIL-SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT--MSLI 673
+ + KD+ +M EK T I +L +++ ++ + L + T LI
Sbjct: 496 HQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLI 555
Query: 674 EPE--QKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD 731
+ E +K + + ++ +M + ++ T+ K+ E + + AK +
Sbjct: 556 QEELLEKASNSSKLESEM---TKKCSQLLTLEKQLE---------EKIVAYSSIAAKNAE 603
Query: 732 FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAK-EELLNTQKKVQDI-VNLEESKK 789
+Q++ ++++ + +N ++K+ +EK K E+ +K+++ + LE+ +
Sbjct: 604 LEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQ 663
Query: 790 QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
Q + LE + E+K E+ + N EA A +V
Sbjct: 664 QFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETI 723
Query: 850 KVKSLDAEIQQHKKKNV--PREMEKIQEANDK-LMEKQKQIMTDRQVLTKKIDTLKDEIA 906
KV+ LD+ ++ K++ V ++E +E +K L +K +++ ++ L K +L++
Sbjct: 724 KVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSE 783
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDE--LNEKLNGINKEELNEKESLIIKQTKLF 964
+ + + L + + +T I N + +D + L ++++ + +E ++ES K K+
Sbjct: 784 QNVILQHTLQQQQQMLQQET-IRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKM- 841
Query: 965 QQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVAL 1024
++K E ++LK R ++ + + K Y+ ++K ++K+I +
Sbjct: 842 EEKCESAAHEADLK------RQKVIELTGTARQVKIEMDQYKEELSK-MEKEIMH--LKR 892
Query: 1025 DKCLMEFHREKMENI-NMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQS 1083
D H +++ I + EL +K +++ ++ TE LT ++R+ +Q+
Sbjct: 893 DGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQN 952
Query: 1084 KNG 1086
+G
Sbjct: 953 AHG 955
Score = 49.6 bits (113), Expect = 7e-05
Identities = 116/634 (18%), Positives = 261/634 (41%), Gaps = 50/634 (7%)
Query: 385 KQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
KQ E E +E+ Q+ E EK + +Q++ + L + + K EM +EN+K
Sbjct: 649 KQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKG-EMKKENMK- 706
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
K++ L L+N+ + E V + D A+ I K E + +
Sbjct: 707 KDEALKALQNQ----VSEETIKVRQLDSALEICKEELVLH--LNQLEGNKEKFEKQLKKK 760
Query: 504 EAERKHIRESLNERRSELTK-AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
E +++ L + L + +E + Q L + T +L+D Q L+ +
Sbjct: 761 SEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQV 820
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXM-NVPGKLEKVTEDL----Q 617
+ + + +++S L R E + E + + G +V ++ +
Sbjct: 821 SKLEQELQKQRESSAEKL--RKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKE 878
Query: 618 RASAKKDEILSMKSLNE-------KITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITM 670
S + EI+ +K E ++ + D +LEK+ V K + T E+T
Sbjct: 879 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTE 938
Query: 671 SLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ- 729
+L + E T + HG++ R +QE++ V +K + E+ ++T ++ K
Sbjct: 939 ALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKME 998
Query: 730 -VDFKQKISTLRNRVKTTQKKLNAHNKKL----QTLYEKKTKAKEELLNTQKKVQ-DIVN 783
D KQ++ + +K +L ++ T+ E + + +++++ + ++ +
Sbjct: 999 IEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELE 1058
Query: 784 LEESKKQLQS--DCXXXXXXXXXXXXAI---TPLEVA-LKEKIEAKTEVVRRNRDLIEAG 837
L+E KQ++S D I E++ LK++IE + ++ +++
Sbjct: 1059 LKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQ 1118
Query: 838 SAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
YIA + + L E++ ++ V ++ EA + ++ Q++I + L+ +
Sbjct: 1119 EQYIA---TQYKEAIDLGQELRL-TREQVQNSHTELAEARHQQVQAQREI----ERLSSE 1170
Query: 898 IDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
++ +K +++ + L + L K + + + ++ ++ E + KE+
Sbjct: 1171 LEDMKQLSKEKDAHGNHLAEELGASKVRE-----AHLEARMQAEIKKLSAEVESLKEAYH 1225
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
++ + A+ + K S++ +LEK+
Sbjct: 1226 MEMISHQENHAKWKISADSQKSSVQQLNEQLEKA 1259
Score = 47.2 bits (107), Expect = 4e-04
Identities = 116/693 (16%), Positives = 275/693 (39%), Gaps = 43/693 (6%)
Query: 105 LAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDS 164
L +K K ++L++ ++T E K + + + H+E+ K I ++D
Sbjct: 608 LMEKNEKIRSLETNINTEHE--KICLAFEKAKKIHLEQHKEM--EKQIERLEAQLEKKDQ 663
Query: 165 SWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELED 224
+ E K + +I + + LDRL K + + ++ A +KA Q ++ +
Sbjct: 664 QFKEQE-KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEA--LKALQNQVSE 720
Query: 225 SYKKNTSFNKEEEKIANEK--SSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIEN 282
K + E E N++E NK + ++++ K++E++ K +I+N
Sbjct: 721 ETIKVRQLDSALEICKEELVLHLNQLEGNK-----EKFEKQLKKKSEEVYCLQKELKIKN 775
Query: 283 ITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXX 342
+ +T+E+ T+ ++ + L+ + ++ + ++ + K + V + +
Sbjct: 776 HSLQETSEQNVILQHTLQQQQQMLQQE-TIRNGELEDTQTKLEKQVSKLEQELQKQRESS 834
Query: 343 XXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINE 402
+ Q +K+ +++ E + +
Sbjct: 835 AEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDG 894
Query: 403 DEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMEL 462
+ KA+ + +M L Q T+L+K+T +KE E ++ + +T+ + + + +T L
Sbjct: 895 ENKAMHLSQLDMI-LDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNA 953
Query: 463 LGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
G + T+ + + E+R+ + L AE + + + +++ EL
Sbjct: 954 HGELKS-----TLRQLQ-ELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELL 1007
Query: 523 KAEDKIYK---ACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD-NSCC 578
+ + + + + VT T + + EQ +++ + K + +LK+ N
Sbjct: 1008 EMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLE-GTLEKSELELKECNKQI 1066
Query: 579 PLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITT 638
N +N E + ++ ++ ++++R + E+ S+ E+
Sbjct: 1067 ESLNDKLQNAKE---QLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIA 1123
Query: 639 LKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDR---- 694
+ E L + + Q++ + + E ++ ++++ DM L +
Sbjct: 1124 TQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDA 1183
Query: 695 ---YIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
++ E +K EA E + +++ +V + K+ + IS N K K+
Sbjct: 1184 HGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKW---KI 1240
Query: 751 NAHNKK--LQTLYEKKTKAKEELLNTQKKVQDI 781
+A ++K +Q L E+ KAK EL Q V ++
Sbjct: 1241 SADSQKSSVQQLNEQLEKAKLELEEAQDTVSNL 1273
>AK091682-1|BAC03719.1| 936|Homo sapiens protein ( Homo sapiens cDNA
FLJ34363 fis, clone FEBRA2015042. ).
Length = 936
Score = 57.2 bits (132), Expect = 3e-07
Identities = 105/504 (20%), Positives = 218/504 (43%), Gaps = 41/504 (8%)
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
+KLQ + ++++ ++ K K+ L ++ E ESE ++ K
Sbjct: 204 QKLQTALAIAENNVQVLQKQLDDAKEGEMA-LLSKHKEVESELAAARERLQQQASDLVLK 262
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+ + +A+ E+ ++K L + + + + + QLE+ + ++ ++L+E E
Sbjct: 263 ASHI--GMLQATQMTQEV-TIKDLESEKSRVNE-RLSQLEEERAFLRSKTQSLDE---EQ 315
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK 728
++E E+K+ AK+ + Y +E+K + + E Q + S+ ++A
Sbjct: 316 KQQILELEKKVNEAKRTQQEY-----YERELKNLQSRLEEEVTQLNEAHSKTLEELAWKH 370
Query: 729 QVDFKQKIST-LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ + S +R++ K HNK L E K + ++EL N ++ ++D +N
Sbjct: 371 HMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQ 430
Query: 788 K-KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ LQ I L+ + +E+++ + ++ + + L E A +
Sbjct: 431 EIGHLQDMVRKSEQGLGSAEGLIASLQDS-QERLQNELDLTKDS--LKETKDALL----- 482
Query: 847 AFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N L+ E QQH++ +E EK++ DK+ + T+ L ++ L++E+
Sbjct: 483 --NVEGELEQERQQHEETIAAMKEEEKLKV--DKMAHDLEIKWTEN--LRQECSKLREEL 536
Query: 906 AKQ--EVYKRDLDDNLCLRKAQTDIT--NWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
Q E K + L L+ + + +WQK+ ++L LN I+ + N + L QT
Sbjct: 537 RLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDL---LNQISLLKQNLEIQLSQSQT 593
Query: 962 KLFQQKAECTGALSELKKSLKGF---RNELEKSLSKDIEKKFREKMYELH-VTKAIDKDI 1017
L Q +A+ T L + L+ + KSL + F+ E +A++ +
Sbjct: 594 SLQQLQAQFTQERQRLTQELEELEERHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 653
Query: 1018 REYAVALDKCLMEFHREKMENINM 1041
++ A + L + HRE ME +
Sbjct: 654 QQKHSAELQSLKDAHRESMEGFRI 677
Score = 42.7 bits (96), Expect = 0.008
Identities = 74/400 (18%), Positives = 173/400 (43%), Gaps = 32/400 (8%)
Query: 617 QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD-TQIKTLNETVEEITMSLIEP 675
+R S ++E ++S + + + +I +LEK++ + TQ + ++ + L
Sbjct: 292 ERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRL--- 348
Query: 676 EQKMTTAKQIHGDM--PMLDRYIQEIKTV-TKKFEAVKEQCGDVDSEMTLDVATAKQVDF 732
E+++T + H + ++ I+ V + K+ D++ + D ++ D
Sbjct: 349 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEE-DK 407
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQ 792
Q L N + + KLN N+++ L + K+++ L + + I +L++S+++LQ
Sbjct: 408 NQLQQELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAEGL---IASLQDSQERLQ 464
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
++ A+ +E L+++ + E + ++ + +A ++ +
Sbjct: 465 NELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAH-DLEIKWTE 523
Query: 853 SLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA--KQE 909
+L E + +++ + E +K + L K ++ R KK++ L ++I+ KQ
Sbjct: 524 NLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQN 583
Query: 910 VYKRDLDDNLCLRKAQTDITNWQK----QDDELNEKLNGINK-------------EELNE 952
+ + L++ Q T ++ + +EL E+ +K EE E
Sbjct: 584 LEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEERHQQRHKSLKEAHVLAFQTMEEEKE 643
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
KE ++ + AE ++S++GFR E+E+ L
Sbjct: 644 KEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQEL 683
Score = 33.1 bits (72), Expect = 6.2
Identities = 29/154 (18%), Positives = 79/154 (51%), Gaps = 5/154 (3%)
Query: 189 DCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN-- 246
D +RL+ +LK ++ V+ + ++ +++ + KEEEK+ +K ++
Sbjct: 458 DSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDL 517
Query: 247 EIEYNKFILLE-SQNQEKIDKRNEQIVETA--KIAEIENITEVQTNEEAENATKTILEKV 303
EI++ + + E S+ +E++ ++E+ ++A ++ ++++ + + + + +L ++
Sbjct: 518 EIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQI 577
Query: 304 ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQ 337
LK + ++Q SQ+ ++ Q + R TQ
Sbjct: 578 SLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQ 611
>AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant 2
protein.
Length = 1715
Score = 57.2 bits (132), Expect = 3e-07
Identities = 101/479 (21%), Positives = 210/479 (43%), Gaps = 56/479 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILS-MKSLNEKITT-LKDTEIP---------QLEKRIVDVDT 656
+LE+ DLQ S + L +K +++T L+DT++ +LEK+ D+
Sbjct: 1082 QLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1141
Query: 657 QIKTLNETV--EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
++ +E E++ ++ E+ M A+ L+ +I T+K +++ +
Sbjct: 1142 ELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ-QLEEKDMDIAGFTQKVVSLEAELQ 1200
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D+ S+ + D A+ +V K+++ L +VK +++L+ +Q L + K + + E+
Sbjct: 1201 DISSQESKDEASLAKV--KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERM 1258
Query: 775 -QKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
Q +++ + +E ++ + C + +EV L+E+ E K +V+R R+L
Sbjct: 1259 RQTHSKEMESRDEEVEEARQSCQKK----------LKQMEVQLEEEYEDKQKVLREKREL 1308
Query: 834 IEAGSAYIA------------KVEVAFNKVKSLDAEIQ---QHKKKNVPREMEKIQEAND 878
E A ++ ++ + K+L A+ Q H K + P + E I + +
Sbjct: 1309 -EGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKN 1366
Query: 879 KLMEKQ---KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC-LRKAQTDITNWQKQ 934
+L E + + R+ + +I+ L +I K L++ L L++ + +I N ++
Sbjct: 1367 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1426
Query: 935 DDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE----- 989
D E +L +K + + + + L Q E EL++ L+ ++++E
Sbjct: 1427 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1486
Query: 990 ---KSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
KSL E K RE L + K + A L + + + E+ + I RE
Sbjct: 1487 MVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE 1545
Score = 41.5 bits (93), Expect = 0.018
Identities = 63/324 (19%), Positives = 136/324 (41%), Gaps = 22/324 (6%)
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQ 219
H E E +K + RFD ++L++ + +++ L E ++ + ++
Sbjct: 1121 HLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEE 1180
Query: 220 KELEDS--YKKNTSFNKEEEKIANEKSSNEIEYNKFIL----LESQ---NQEKIDKR--N 268
K+++ + +K S E + I++++S +E K LE++ +E++D++
Sbjct: 1181 KDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGT 1240
Query: 269 EQIVETAKIA-EIENITEVQTN-EEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQG 326
Q++E AK+ E+E QT+ +E E+ + + E +S + K + Q +EE + Q
Sbjct: 1241 IQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQK 1300
Query: 327 FVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHK- 385
+ E R + D+ +
Sbjct: 1301 VLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE 1360
Query: 386 --QAENELNIEE--CQQEINED---EKAVEQYEQEMDELSQKITKLQKQTAKL-KEKEMI 437
Q +N+L E C + E +E ++D++++ T L++Q ++L +EK I
Sbjct: 1361 IAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEI 1420
Query: 438 EENLKTKEKQLIVLKNKHKTALME 461
+ L+ ++ + L KHK A+ +
Sbjct: 1421 QNRLEEDQEDMNELMKKHKAAVAQ 1444
Score = 35.5 bits (78), Expect = 1.2
Identities = 66/390 (16%), Positives = 161/390 (41%), Gaps = 31/390 (7%)
Query: 402 EDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEM-IEENLKTKEKQLIVLKNKHKTAL 459
E E+ + + +EM+ +++ + ++ K LK+ E+ +EE + K+K L K + + L
Sbjct: 1254 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE-KRELEGKL 1312
Query: 460 MELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRS 519
L V +DF + E +R ++ L+ RE + + ++
Sbjct: 1313 ATLSDQVNRRDF-----ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKN 1366
Query: 520 ELTKAEDKIYKAC-GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN--S 576
+L ++E A + +V + ++ + + L+ + + + K ++++
Sbjct: 1367 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1426
Query: 577 CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD------EILSMK 630
N + ++ +LE+ ++ Q K E L
Sbjct: 1427 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1486
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMP 690
+++ + + ++ +I +LE R+ TQ+K L E + L E +K+T + +
Sbjct: 1487 MVDKSLVSRQEAKIRELETRLEFERTQVKRL----ESLASRLKENMEKLTEERDQR--IA 1540
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
+R ++ K + ++ KE+ G++ + A+ K+ + + + +L ++ Q L
Sbjct: 1541 AENREKEQNKRLQRQLRDTKEEMGELARKEA--EASRKKHELEMDLESLEAANQSLQADL 1598
Query: 751 NAHNKKLQTLY-----EKKTKAKEELLNTQ 775
K++ L E ++ E+L+N++
Sbjct: 1599 KLAFKRIGDLQAAIEDEMESDENEDLINSE 1628
>AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant 1
protein.
Length = 2046
Score = 57.2 bits (132), Expect = 3e-07
Identities = 101/479 (21%), Positives = 210/479 (43%), Gaps = 56/479 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILS-MKSLNEKITT-LKDTEIP---------QLEKRIVDVDT 656
+LE+ DLQ S + L +K +++T L+DT++ +LEK+ D+
Sbjct: 1398 QLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1457
Query: 657 QIKTLNETV--EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCG 714
++ +E E++ ++ E+ M A+ L+ +I T+K +++ +
Sbjct: 1458 ELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ-QLEEKDMDIAGFTQKVVSLEAELQ 1516
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D+ S+ + D A+ +V K+++ L +VK +++L+ +Q L + K + + E+
Sbjct: 1517 DISSQESKDEASLAKV--KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERM 1574
Query: 775 -QKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDL 833
Q +++ + +E ++ + C + +EV L+E+ E K +V+R R+L
Sbjct: 1575 RQTHSKEMESRDEEVEEARQSCQKK----------LKQMEVQLEEEYEDKQKVLREKREL 1624
Query: 834 IEAGSAYIA------------KVEVAFNKVKSLDAEIQ---QHKKKNVPREMEKIQEAND 878
E A ++ ++ + K+L A+ Q H K + P + E I + +
Sbjct: 1625 -EGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKN 1682
Query: 879 KLMEKQ---KQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC-LRKAQTDITNWQKQ 934
+L E + + R+ + +I+ L +I K L++ L L++ + +I N ++
Sbjct: 1683 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1742
Query: 935 DDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE----- 989
D E +L +K + + + + L Q E EL++ L+ ++++E
Sbjct: 1743 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1802
Query: 990 ---KSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRE 1045
KSL E K RE L + K + A L + + + E+ + I RE
Sbjct: 1803 MVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE 1861
Score = 38.7 bits (86), Expect = 0.12
Identities = 72/410 (17%), Positives = 172/410 (41%), Gaps = 35/410 (8%)
Query: 402 EDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEM-IEENLKTKEKQLIVLKNKHKTAL 459
E E+ + + +EM+ +++ + ++ K LK+ E+ +EE + K+K L K + + L
Sbjct: 1570 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE-KRELEGKL 1628
Query: 460 MELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRS 519
L V +DF + E +R ++ L+ RE + + ++
Sbjct: 1629 ATLSDQVNRRDF-----ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKRE-IAQLKN 1682
Query: 520 ELTKAEDKIYKAC-GTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDN--S 576
+L ++E A + +V + ++ + + L+ + + + K ++++
Sbjct: 1683 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1742
Query: 577 CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD------EILSMK 630
N + ++ +LE+ ++ Q K E L
Sbjct: 1743 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1802
Query: 631 SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMP 690
+++ + + ++ +I +LE R+ TQ+K L E + L E +K+T + +
Sbjct: 1803 MVDKSLVSRQEAKIRELETRLEFERTQVKRL----ESLASRLKENMEKLTEERDQR--IA 1856
Query: 691 MLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
+R ++ K + ++ KE+ G++ + A+ K+ + + + +L ++ Q L
Sbjct: 1857 AENREKEQNKRLQRQLRDTKEEMGELARKEA--EASRKKHELEMDLESLEAANQSLQADL 1914
Query: 751 NAHNKKLQTLY-----EKKTKAKEELLNTQKKVQDIV-NLEESKKQLQSD 794
K++ L E ++ E+L+N+ +QD+V ++ K +L+ D
Sbjct: 1915 KLAFKRIGDLQAAIEDEMESDENEDLINS---LQDMVTKYQKRKNKLEGD 1961
>AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 56.8 bits (131), Expect = 4e-07
Identities = 79/440 (17%), Positives = 185/440 (42%), Gaps = 24/440 (5%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LE+ ++LQ+A + E+ + E + E+ L KR+++++ + + + +T +
Sbjct: 344 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQ 403
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ +++ +K++ ++ L + + E++ + + F K +C + + +
Sbjct: 404 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLT 463
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDIVNL 784
K D ++ +++RVK + + K +L + TK K L++ +K + + +
Sbjct: 464 K--DLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 521
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
EE K + L K+ ++ K+E+ + +L I K+
Sbjct: 522 EERK--VDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKL 579
Query: 845 EVAFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQV--LTKKIDTL 901
+ K L + KK+ + E+E+ + D ++ LT +I+ L
Sbjct: 580 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 639
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
K + + EV + D L K + + +++ +K N ++ ++L E + I K
Sbjct: 640 KKRLQQLEVVEGD------LMKTEDEYDQLEQKFRTEQDKANFLS-QQLEEIKHQIAKNK 692
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ +K E +EL+ R LE++ S+D++ + + ++H + + +
Sbjct: 693 AI--EKGEVVSQEAELR-----HRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQ 745
Query: 1022 VALDKCLMEFHREKMENINM 1041
V F E+ +N NM
Sbjct: 746 VDYSVLQQRFMEEENKNKNM 765
Score = 38.3 bits (85), Expect = 0.16
Identities = 103/587 (17%), Positives = 236/587 (40%), Gaps = 50/587 (8%)
Query: 385 KQAENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN 440
K+ EN + + + E+ + + V++ + +++L + K+Q T KL+E+E +
Sbjct: 225 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKA 284
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXX 500
+ +K K+ ++ K +E+ F+ + ++ N+
Sbjct: 285 ITSKSKE-----DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLT 339
Query: 501 XXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E + ++L + EL + DKI K CG S VE L+ + VL+
Sbjct: 340 QRIE-ELEETNKNLQKAEEELQELRDKIAKGECGN-------SSLMAEVENLR--KRVLE 389
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
K + K S C + + E +LEK+ E ++
Sbjct: 390 ME----GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKS 445
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ ++ + +T E+ ++ R+ +++ L + E+++ + K
Sbjct: 446 KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA--ELSLKDDLTKLKS 503
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T + M+++ QE + V + K + G V +DV T K ++ +K+ L
Sbjct: 504 FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-----MDV-TEKLIEESKKLLKL 557
Query: 740 RNRVKTTQKKLNAHNKKL-QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
++ ++ L +L L ++ K+ E + + + +EE ++++
Sbjct: 558 KSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREI------T 611
Query: 799 XXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI 858
P + +KE + + E +++ +E + K E +++++
Sbjct: 612 RGRSRKGSELTCPEDNKIKE-LTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRT 669
Query: 859 QQHKKKNVPREMEKI--QEANDKLMEKQKQIMTDRQVLTK-KIDTLKDEIAKQEV--YKR 913
+Q K + +++E+I Q A +K +EK + + + ++ + +++ K K EV K
Sbjct: 670 EQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKE 729
Query: 914 DLDDNL----CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
+ + + L + Q D + Q++ E K + +E LN + L
Sbjct: 730 KIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKEL 776
Score = 36.7 bits (81), Expect = 0.50
Identities = 83/424 (19%), Positives = 175/424 (41%), Gaps = 27/424 (6%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
HK + EE ++ E Q ++ L+Q+I +L++ L++ E + L+
Sbjct: 305 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRD 364
Query: 444 KEKQLIVLKNKHKTALMELLGNVPE---KDFAVTINKFEC-EVRNEVXXXXXXXXXXXXX 499
K + + + L V E KD +T + +C E+R ++
Sbjct: 365 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 424
Query: 500 XXXLE---AERKHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQ 555
L+ +E + + E+ ++ +SE T+ + K T+ L + V++L+ +
Sbjct: 425 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 484
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRG--FENESEXXXXXXXXXXXXMNVPGKLEKVT 613
+ L+ + + +LK + + R E + GK+ VT
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 544
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E L S K +L +KS + EK+ L E +L ++ + + L+ +V+ + L
Sbjct: 545 EKLIEESKK---LLKLKSEMEEKVYNL-TRERDELIGKLKSEEEKSSELSCSVDLLKKRL 600
Query: 673 --IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
IE ++ T + + +IK +T + E +K++ L+V +
Sbjct: 601 DGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL------QQLEVVEGDLM 654
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK--KTKA--KEELLNTQKKVQDIVNLEE 786
+ + L + +T Q K N +++L+ + + K KA K E+++ + +++ LEE
Sbjct: 655 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEE 714
Query: 787 SKKQ 790
+K +
Sbjct: 715 AKSR 718
>AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 56.8 bits (131), Expect = 4e-07
Identities = 79/440 (17%), Positives = 185/440 (42%), Gaps = 24/440 (5%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LE+ ++LQ+A + E+ + E + E+ L KR+++++ + + + +T +
Sbjct: 245 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQ 304
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ +++ +K++ ++ L + + E++ + + F K +C + + +
Sbjct: 305 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLT 364
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDIVNL 784
K D ++ +++RVK + + K +L + TK K L++ +K + + +
Sbjct: 365 K--DLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 422
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
EE K + L K+ ++ K+E+ + +L I K+
Sbjct: 423 EERK--VDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKL 480
Query: 845 EVAFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQV--LTKKIDTL 901
+ K L + KK+ + E+E+ + D ++ LT +I+ L
Sbjct: 481 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 540
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
K + + EV + D L K + + +++ +K N ++ ++L E + I K
Sbjct: 541 KKRLQQLEVVEGD------LMKTEDEYDQLEQKFRTEQDKANFLS-QQLEEIKHQIAKNK 593
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ +K E +EL+ R LE++ S+D++ + + ++H + + +
Sbjct: 594 AI--EKGEVVSQEAELR-----HRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQ 646
Query: 1022 VALDKCLMEFHREKMENINM 1041
V F E+ +N NM
Sbjct: 647 VDYSVLQQRFMEEENKNKNM 666
Score = 38.3 bits (85), Expect = 0.16
Identities = 103/587 (17%), Positives = 236/587 (40%), Gaps = 50/587 (8%)
Query: 385 KQAENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN 440
K+ EN + + + E+ + + V++ + +++L + K+Q T KL+E+E +
Sbjct: 126 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKA 185
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXX 500
+ +K K+ ++ K +E+ F+ + ++ N+
Sbjct: 186 ITSKSKE-----DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLT 240
Query: 501 XXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E + ++L + EL + DKI K CG S VE L+ + VL+
Sbjct: 241 QRIE-ELEETNKNLQKAEEELQELRDKIAKGECGN-------SSLMAEVENLR--KRVLE 290
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
K + K S C + + E +LEK+ E ++
Sbjct: 291 ME----GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKS 346
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ ++ + +T E+ ++ R+ +++ L + E+++ + K
Sbjct: 347 KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA--ELSLKDDLTKLKS 404
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T + M+++ QE + V + K + G V +DV T K ++ +K+ L
Sbjct: 405 FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-----MDV-TEKLIEESKKLLKL 458
Query: 740 RNRVKTTQKKLNAHNKKL-QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
++ ++ L +L L ++ K+ E + + + +EE ++++
Sbjct: 459 KSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREI------T 512
Query: 799 XXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI 858
P + +KE + + E +++ +E + K E +++++
Sbjct: 513 RGRSRKGSELTCPEDNKIKE-LTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRT 570
Query: 859 QQHKKKNVPREMEKI--QEANDKLMEKQKQIMTDRQVLTK-KIDTLKDEIAKQEV--YKR 913
+Q K + +++E+I Q A +K +EK + + + ++ + +++ K K EV K
Sbjct: 571 EQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKE 630
Query: 914 DLDDNL----CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
+ + + L + Q D + Q++ E K + +E LN + L
Sbjct: 631 KIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKEL 677
Score = 36.7 bits (81), Expect = 0.50
Identities = 83/424 (19%), Positives = 175/424 (41%), Gaps = 27/424 (6%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
HK + EE ++ E Q ++ L+Q+I +L++ L++ E + L+
Sbjct: 206 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRD 265
Query: 444 KEKQLIVLKNKHKTALMELLGNVPE---KDFAVTINKFEC-EVRNEVXXXXXXXXXXXXX 499
K + + + L V E KD +T + +C E+R ++
Sbjct: 266 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 325
Query: 500 XXXLE---AERKHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQ 555
L+ +E + + E+ ++ +SE T+ + K T+ L + V++L+ +
Sbjct: 326 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 385
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRG--FENESEXXXXXXXXXXXXMNVPGKLEKVT 613
+ L+ + + +LK + + R E + GK+ VT
Sbjct: 386 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 445
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E L S K +L +KS + EK+ L E +L ++ + + L+ +V+ + L
Sbjct: 446 EKLIEESKK---LLKLKSEMEEKVYNL-TRERDELIGKLKSEEEKSSELSCSVDLLKKRL 501
Query: 673 --IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
IE ++ T + + +IK +T + E +K++ L+V +
Sbjct: 502 DGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL------QQLEVVEGDLM 555
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK--KTKA--KEELLNTQKKVQDIVNLEE 786
+ + L + +T Q K N +++L+ + + K KA K E+++ + +++ LEE
Sbjct: 556 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEE 615
Query: 787 SKKQ 790
+K +
Sbjct: 616 AKSR 619
>AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 56.8 bits (131), Expect = 4e-07
Identities = 79/440 (17%), Positives = 185/440 (42%), Gaps = 24/440 (5%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LE+ ++LQ+A + E+ + E + E+ L KR+++++ + + + +T +
Sbjct: 344 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQ 403
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ +++ +K++ ++ L + + E++ + + F K +C + + +
Sbjct: 404 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLT 463
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDIVNL 784
K D ++ +++RVK + + K +L + TK K L++ +K + + +
Sbjct: 464 K--DLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 521
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
EE K + L K+ ++ K+E+ + +L I K+
Sbjct: 522 EERK--VDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKL 579
Query: 845 EVAFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQV--LTKKIDTL 901
+ K L + KK+ + E+E+ + D ++ LT +I+ L
Sbjct: 580 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 639
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
K + + EV + D L K + + +++ +K N ++ ++L E + I K
Sbjct: 640 KKRLQQLEVVEGD------LMKTEDEYDQLEQKFRTEQDKANFLS-QQLEEIKHQIAKNK 692
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ +K E +EL+ R LE++ S+D++ + + ++H + + +
Sbjct: 693 AI--EKGEVVSQEAELR-----HRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQ 745
Query: 1022 VALDKCLMEFHREKMENINM 1041
V F E+ +N NM
Sbjct: 746 VDYSVLQQRFMEEENKNKNM 765
Score = 38.3 bits (85), Expect = 0.16
Identities = 103/587 (17%), Positives = 236/587 (40%), Gaps = 50/587 (8%)
Query: 385 KQAENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN 440
K+ EN + + + E+ + + V++ + +++L + K+Q T KL+E+E +
Sbjct: 225 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKA 284
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXX 500
+ +K K+ ++ K +E+ F+ + ++ N+
Sbjct: 285 ITSKSKE-----DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLT 339
Query: 501 XXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E + ++L + EL + DKI K CG S VE L+ + VL+
Sbjct: 340 QRIE-ELEETNKNLQKAEEELQELRDKIAKGECGN-------SSLMAEVENLR--KRVLE 389
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
K + K S C + + E +LEK+ E ++
Sbjct: 390 ME----GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKS 445
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ ++ + +T E+ ++ R+ +++ L + E+++ + K
Sbjct: 446 KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA--ELSLKDDLTKLKS 503
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T + M+++ QE + V + K + G V +DV T K ++ +K+ L
Sbjct: 504 FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-----MDV-TEKLIEESKKLLKL 557
Query: 740 RNRVKTTQKKLNAHNKKL-QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
++ ++ L +L L ++ K+ E + + + +EE ++++
Sbjct: 558 KSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREI------T 611
Query: 799 XXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI 858
P + +KE + + E +++ +E + K E +++++
Sbjct: 612 RGRSRKGSELTCPEDNKIKE-LTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRT 669
Query: 859 QQHKKKNVPREMEKI--QEANDKLMEKQKQIMTDRQVLTK-KIDTLKDEIAKQEV--YKR 913
+Q K + +++E+I Q A +K +EK + + + ++ + +++ K K EV K
Sbjct: 670 EQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKE 729
Query: 914 DLDDNL----CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
+ + + L + Q D + Q++ E K + +E LN + L
Sbjct: 730 KIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKEL 776
Score = 36.7 bits (81), Expect = 0.50
Identities = 83/424 (19%), Positives = 175/424 (41%), Gaps = 27/424 (6%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
HK + EE ++ E Q ++ L+Q+I +L++ L++ E + L+
Sbjct: 305 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRD 364
Query: 444 KEKQLIVLKNKHKTALMELLGNVPE---KDFAVTINKFEC-EVRNEVXXXXXXXXXXXXX 499
K + + + L V E KD +T + +C E+R ++
Sbjct: 365 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 424
Query: 500 XXXLE---AERKHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQ 555
L+ +E + + E+ ++ +SE T+ + K T+ L + V++L+ +
Sbjct: 425 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 484
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRG--FENESEXXXXXXXXXXXXMNVPGKLEKVT 613
+ L+ + + +LK + + R E + GK+ VT
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 544
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E L S K +L +KS + EK+ L E +L ++ + + L+ +V+ + L
Sbjct: 545 EKLIEESKK---LLKLKSEMEEKVYNL-TRERDELIGKLKSEEEKSSELSCSVDLLKKRL 600
Query: 673 --IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
IE ++ T + + +IK +T + E +K++ L+V +
Sbjct: 601 DGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL------QQLEVVEGDLM 654
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK--KTKA--KEELLNTQKKVQDIVNLEE 786
+ + L + +T Q K N +++L+ + + K KA K E+++ + +++ LEE
Sbjct: 655 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEE 714
Query: 787 SKKQ 790
+K +
Sbjct: 715 AKSR 718
>AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 56.8 bits (131), Expect = 4e-07
Identities = 79/440 (17%), Positives = 185/440 (42%), Gaps = 24/440 (5%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LE+ ++LQ+A + E+ + E + E+ L KR+++++ + + + +T +
Sbjct: 245 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQ 304
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ +++ +K++ ++ L + + E++ + + F K +C + + +
Sbjct: 305 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLT 364
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDIVNL 784
K D ++ +++RVK + + K +L + TK K L++ +K + + +
Sbjct: 365 K--DLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 422
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
EE K + L K+ ++ K+E+ + +L I K+
Sbjct: 423 EERK--VDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKL 480
Query: 845 EVAFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQV--LTKKIDTL 901
+ K L + KK+ + E+E+ + D ++ LT +I+ L
Sbjct: 481 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 540
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
K + + EV + D L K + + +++ +K N ++ ++L E + I K
Sbjct: 541 KKRLQQLEVVEGD------LMKTEDEYDQLEQKFRTEQDKANFLS-QQLEEIKHQIAKNK 593
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ +K E +EL+ R LE++ S+D++ + + ++H + + +
Sbjct: 594 AI--EKGEVVSQEAELR-----HRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQ 646
Query: 1022 VALDKCLMEFHREKMENINM 1041
V F E+ +N NM
Sbjct: 647 VDYSVLQQRFMEEENKNKNM 666
Score = 38.3 bits (85), Expect = 0.16
Identities = 103/587 (17%), Positives = 236/587 (40%), Gaps = 50/587 (8%)
Query: 385 KQAENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN 440
K+ EN + + + E+ + + V++ + +++L + K+Q T KL+E+E +
Sbjct: 126 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKA 185
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXX 500
+ +K K+ ++ K +E+ F+ + ++ N+
Sbjct: 186 ITSKSKE-----DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLT 240
Query: 501 XXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E + ++L + EL + DKI K CG S VE L+ + VL+
Sbjct: 241 QRIE-ELEETNKNLQKAEEELQELRDKIAKGECGN-------SSLMAEVENLR--KRVLE 290
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
K + K S C + + E +LEK+ E ++
Sbjct: 291 ME----GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKS 346
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ ++ + +T E+ ++ R+ +++ L + E+++ + K
Sbjct: 347 KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA--ELSLKDDLTKLKS 404
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T + M+++ QE + V + K + G V +DV T K ++ +K+ L
Sbjct: 405 FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-----MDV-TEKLIEESKKLLKL 458
Query: 740 RNRVKTTQKKLNAHNKKL-QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
++ ++ L +L L ++ K+ E + + + +EE ++++
Sbjct: 459 KSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREI------T 512
Query: 799 XXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI 858
P + +KE + + E +++ +E + K E +++++
Sbjct: 513 RGRSRKGSELTCPEDNKIKE-LTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRT 570
Query: 859 QQHKKKNVPREMEKI--QEANDKLMEKQKQIMTDRQVLTK-KIDTLKDEIAKQEV--YKR 913
+Q K + +++E+I Q A +K +EK + + + ++ + +++ K K EV K
Sbjct: 571 EQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKE 630
Query: 914 DLDDNL----CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
+ + + L + Q D + Q++ E K + +E LN + L
Sbjct: 631 KIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKEL 677
Score = 36.7 bits (81), Expect = 0.50
Identities = 83/424 (19%), Positives = 175/424 (41%), Gaps = 27/424 (6%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
HK + EE ++ E Q ++ L+Q+I +L++ L++ E + L+
Sbjct: 206 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRD 265
Query: 444 KEKQLIVLKNKHKTALMELLGNVPE---KDFAVTINKFEC-EVRNEVXXXXXXXXXXXXX 499
K + + + L V E KD +T + +C E+R ++
Sbjct: 266 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 325
Query: 500 XXXLE---AERKHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQ 555
L+ +E + + E+ ++ +SE T+ + K T+ L + V++L+ +
Sbjct: 326 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 385
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRG--FENESEXXXXXXXXXXXXMNVPGKLEKVT 613
+ L+ + + +LK + + R E + GK+ VT
Sbjct: 386 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 445
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E L S K +L +KS + EK+ L E +L ++ + + L+ +V+ + L
Sbjct: 446 EKLIEESKK---LLKLKSEMEEKVYNL-TRERDELIGKLKSEEEKSSELSCSVDLLKKRL 501
Query: 673 --IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
IE ++ T + + +IK +T + E +K++ L+V +
Sbjct: 502 DGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL------QQLEVVEGDLM 555
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK--KTKA--KEELLNTQKKVQDIVNLEE 786
+ + L + +T Q K N +++L+ + + K KA K E+++ + +++ LEE
Sbjct: 556 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEE 615
Query: 787 SKKQ 790
+K +
Sbjct: 616 AKSR 619
>AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin heavy
chain SM1 protein.
Length = 622
Score = 56.8 bits (131), Expect = 4e-07
Identities = 90/458 (19%), Positives = 202/458 (44%), Gaps = 30/458 (6%)
Query: 611 KVTEDLQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVE 666
++ +L++ K D++L+ K+++ K +D E + E + + + ++ E E
Sbjct: 91 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 150
Query: 667 EIT----MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E+ M E E +++ + ++ L++ + ++T ++ + E+ D + + T
Sbjct: 151 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATE 209
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
D +V+ + ++ ++ ++LQ L+E +T+ ++E
Sbjct: 210 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK 269
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
LE K L+ + L+ +K+ + + E R +RD I A +
Sbjct: 270 KKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKD-FQRELEDARASRDEIFATAKEN 328
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKID 899
K K KSL+A++ Q ++ E + Q +K L E+ ++ R L +
Sbjct: 329 EK------KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR 382
Query: 900 TLKDEIAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESL 956
L+ IA+ E +L++ +A +D + +Q ++L NE + + NE
Sbjct: 383 RLEARIAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 439
Query: 957 IIKQTKLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
+ +Q K + K E GA+ S+ K ++ ++ + L + +E++ REK K D
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKD 498
Query: 1015 KDIREYAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
K ++E + + ++ + E ++E+ E N +++L R++
Sbjct: 499 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 536
Score = 52.0 bits (119), Expect = 1e-05
Identities = 76/305 (24%), Positives = 140/305 (45%), Gaps = 33/305 (10%)
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT----QKKVQDIV 782
AKQ + ++ ISTL ++ ++KKL ++ L E K + ++E+ N ++K
Sbjct: 8 AKQ-NLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 66
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLE--------VALKEKIEAKTEVVRRNRDLI 834
LE++K +LQ + ++ LE + +EK + R+R
Sbjct: 67 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 126
Query: 835 EAGSAYIAKVEVAFNKVKSLDA-EIQQHKKKNVPREMEKIQEANDKL------MEKQKQI 887
EA + +A ++L+A E + K + EME + + D + +EK K+
Sbjct: 127 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 186
Query: 888 M-TDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGIN 946
+ T + + +++ L+DE+ E K L+ N+ K Q + + Q +D++ EK +
Sbjct: 187 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE-RDLQARDEQNEEKRRQLQ 245
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYE 1006
+ +L+E E+ + + K Q+A A KK L+G +LE L D K RE+ +
Sbjct: 246 R-QLHEYETELEDERK---QRALAAAA----KKKLEGDLKDLE--LQADSAIKGREEAIK 295
Query: 1007 LHVTK 1011
HV K
Sbjct: 296 -HVRK 299
Score = 46.4 bits (105), Expect = 6e-04
Identities = 95/535 (17%), Positives = 221/535 (41%), Gaps = 55/535 (10%)
Query: 385 KQAEN-ELNIEECQQEINEDEKAVEQYEQEMDEL-------SQKITKLQKQTAKLKEKEM 436
K+ EN EE ++ EK + +QE+D+L Q ++ L+K+ K +
Sbjct: 49 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 108
Query: 437 IEENLKTK---EKQLIVLKNKHK-TALMELLGNVPEK-DFAVTINKFECEVRNEVXXXXX 491
E+N+ +K E+ + + K T + L + E + + + ++ E+
Sbjct: 109 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 168
Query: 492 XXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-PYDVTLSKYTTTVEK 550
LE ++ + + E +++L + ED++ + +V + E+
Sbjct: 169 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 228
Query: 551 ---LQDEQNVLQSSMFI--INKYKGQLKDN----SCCPLCNRGFENESEXXXXXXXXXXX 601
+DEQN + +++Y+ +L+D + + E + +
Sbjct: 229 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 288
Query: 602 ----XMNVPGKLEKVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVD 653
+ KL+ +D QR A A +DEI + NEK + ++ QL++ +
Sbjct: 289 GREEAIKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 348
Query: 654 VDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQC 713
+ K + EE+ L A + G + D + + + E ++E+
Sbjct: 349 AERARKQADLEKEELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 399
Query: 714 GDVDS-EMTLDVATAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAK 768
G++++ + AT + +++T R+ + ++ +++L NK+L++ L+E + K
Sbjct: 400 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 459
Query: 769 EELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTE 825
+ +T I LE QL+ ++ + LKE ++E + +
Sbjct: 460 SKFKST------IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 513
Query: 826 VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
+ + ++ E G+A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 514 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 567
Score = 40.3 bits (90), Expect = 0.041
Identities = 66/378 (17%), Positives = 158/378 (41%), Gaps = 17/378 (4%)
Query: 624 DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK 683
+E+ + ++L I+TL + ++ +K++ D + ++ L E + + Q+
Sbjct: 4 EEMEAKQNLERHISTL-NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 62
Query: 684 QIHGDMPML-DRYIQEIKTVTKKFEAVKEQCGDVDSEMT-LDVATAKQVDFKQKISTLRN 741
+ + +R QE+ + + ++ +++ + D A++ + K + R+
Sbjct: 63 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 122
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXX 800
R + ++ L E+ +AKEEL T K ++ ++ +L SK + +
Sbjct: 123 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 182
Query: 801 XXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ 860
+ ++ L E++E + + + +E + ++ F + L A +Q
Sbjct: 183 SKRALETQMEEMKTQL-EELEDELQATEDAKLRLEVN---MQALKGQFE--RDLQARDEQ 236
Query: 861 HKKKNVPREMEK-IQEANDKLMEKQKQIMTDRQVLTKKIDTLKD-EIAKQEVYKRDLDDN 918
+++K R++++ + E +L +++KQ K LKD E+ K +
Sbjct: 237 NEEKR--RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI 294
Query: 919 LCLRKAQTDITNWQKQDDEL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
+RK Q + ++Q++ ++ +++ KE + +SL +L + A A
Sbjct: 295 KHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 354
Query: 976 ELKKSLKGFRNELEKSLS 993
+ + EL SLS
Sbjct: 355 QADLEKEELAEELASSLS 372
>AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin heavy
chain SM2 protein.
Length = 588
Score = 56.8 bits (131), Expect = 4e-07
Identities = 90/458 (19%), Positives = 202/458 (44%), Gaps = 30/458 (6%)
Query: 611 KVTEDLQRASAKKDEILSM-KSLNEKITTLKD---TEIPQLEKRIVDVDTQIKTLNETVE 666
++ +L++ K D++L+ K+++ K +D E + E + + + ++ E E
Sbjct: 91 QLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE 150
Query: 667 EIT----MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTL 722
E+ M E E +++ + ++ L++ + ++T ++ + E+ D + + T
Sbjct: 151 ELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELED-ELQATE 209
Query: 723 DVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDI 781
D +V+ + ++ ++ ++LQ L+E +T+ ++E
Sbjct: 210 DAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK 269
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
LE K L+ + L+ +K+ + + E R +RD I A +
Sbjct: 270 KKLEGDLKDLELQADSAIKGREEAIKHVRKLQAQMKD-FQRELEDARASRDEIFATAKEN 328
Query: 842 AKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK--LMEKQKQIMTDRQVLTKKID 899
K K KSL+A++ Q ++ E + Q +K L E+ ++ R L +
Sbjct: 329 EK------KAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR 382
Query: 900 TLKDEIAKQEVYKRDLDDNLCLRKAQTD-ITNWQKQDDEL-NEKLNGINKEELNEK-ESL 956
L+ IA+ E +L++ +A +D + +Q ++L NE + + NE
Sbjct: 383 RLEARIAQLE---EELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQ 439
Query: 957 IIKQTKLFQQKA-ECTGAL-SELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAID 1014
+ +Q K + K E GA+ S+ K ++ ++ + L + +E++ REK K D
Sbjct: 440 LERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ-LEEQVEQEAREKQAATKSLKQKD 498
Query: 1015 KDIREYAVAL--DKCLMEFHREKMENINMIIRELWRKI 1050
K ++E + + ++ + E ++E+ E N +++L R++
Sbjct: 499 KKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQL 536
Score = 52.0 bits (119), Expect = 1e-05
Identities = 76/305 (24%), Positives = 140/305 (45%), Gaps = 33/305 (10%)
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT----QKKVQDIV 782
AKQ + ++ ISTL ++ ++KKL ++ L E K + ++E+ N ++K
Sbjct: 8 AKQ-NLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYD 66
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLE--------VALKEKIEAKTEVVRRNRDLI 834
LE++K +LQ + ++ LE + +EK + R+R
Sbjct: 67 KLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEA 126
Query: 835 EAGSAYIAKVEVAFNKVKSLDA-EIQQHKKKNVPREMEKIQEANDKL------MEKQKQI 887
EA + +A ++L+A E + K + EME + + D + +EK K+
Sbjct: 127 EAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRA 186
Query: 888 M-TDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGIN 946
+ T + + +++ L+DE+ E K L+ N+ K Q + + Q +D++ EK +
Sbjct: 187 LETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFE-RDLQARDEQNEEKRRQLQ 245
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYE 1006
+ +L+E E+ + + K Q+A A KK L+G +LE L D K RE+ +
Sbjct: 246 R-QLHEYETELEDERK---QRALAAAA----KKKLEGDLKDLE--LQADSAIKGREEAIK 295
Query: 1007 LHVTK 1011
HV K
Sbjct: 296 -HVRK 299
Score = 46.4 bits (105), Expect = 6e-04
Identities = 95/535 (17%), Positives = 221/535 (41%), Gaps = 55/535 (10%)
Query: 385 KQAEN-ELNIEECQQEINEDEKAVEQYEQEMDEL-------SQKITKLQKQTAKLKEKEM 436
K+ EN EE ++ EK + +QE+D+L Q ++ L+K+ K +
Sbjct: 49 KEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 108
Query: 437 IEENLKTK---EKQLIVLKNKHK-TALMELLGNVPEK-DFAVTINKFECEVRNEVXXXXX 491
E+N+ +K E+ + + K T + L + E + + + ++ E+
Sbjct: 109 EEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVS 168
Query: 492 XXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQ-PYDVTLSKYTTTVEK 550
LE ++ + + E +++L + ED++ + +V + E+
Sbjct: 169 SKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFER 228
Query: 551 ---LQDEQNVLQSSMFI--INKYKGQLKDN----SCCPLCNRGFENESEXXXXXXXXXXX 601
+DEQN + +++Y+ +L+D + + E + +
Sbjct: 229 DLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIK 288
Query: 602 ----XMNVPGKLEKVTEDLQR----ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVD 653
+ KL+ +D QR A A +DEI + NEK + ++ QL++ +
Sbjct: 289 GREEAIKHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAA 348
Query: 654 VDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQC 713
+ K + EE+ L A + G + D + + + E ++E+
Sbjct: 349 AERARKQADLEKEELAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQ 399
Query: 714 GDVDS-EMTLDVATAKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAK 768
G++++ + AT + +++T R+ + ++ +++L NK+L++ L+E + K
Sbjct: 400 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVK 459
Query: 769 EELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTE 825
+ +T I LE QL+ ++ + LKE ++E + +
Sbjct: 460 SKFKST------IAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERK 513
Query: 826 VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
+ + ++ E G+A + +++ + + I +++K + RE+++ E+N+ +
Sbjct: 514 MAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 567
Score = 40.3 bits (90), Expect = 0.041
Identities = 66/378 (17%), Positives = 158/378 (41%), Gaps = 17/378 (4%)
Query: 624 DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK 683
+E+ + ++L I+TL + ++ +K++ D + ++ L E + + Q+
Sbjct: 4 EEMEAKQNLERHISTL-NIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKA 62
Query: 684 QIHGDMPML-DRYIQEIKTVTKKFEAVKEQCGDVDSEMT-LDVATAKQVDFKQKISTLRN 741
+ + +R QE+ + + ++ +++ + D A++ + K + R+
Sbjct: 63 AAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERD 122
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ-DIVNLEESKKQLQSDCXXXXX 800
R + ++ L E+ +AKEEL T K ++ ++ +L SK + +
Sbjct: 123 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 182
Query: 801 XXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ 860
+ ++ L E++E + + + +E + ++ F + L A +Q
Sbjct: 183 SKRALETQMEEMKTQL-EELEDELQATEDAKLRLEVN---MQALKGQFE--RDLQARDEQ 236
Query: 861 HKKKNVPREMEK-IQEANDKLMEKQKQIMTDRQVLTKKIDTLKD-EIAKQEVYKRDLDDN 918
+++K R++++ + E +L +++KQ K LKD E+ K +
Sbjct: 237 NEEKR--RQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAI 294
Query: 919 LCLRKAQTDITNWQKQDDEL---NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
+RK Q + ++Q++ ++ +++ KE + +SL +L + A A
Sbjct: 295 KHVRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 354
Query: 976 ELKKSLKGFRNELEKSLS 993
+ + EL SLS
Sbjct: 355 QADLEKEELAEELASSLS 372
>AB086011-1|BAC77067.1| 1213|Homo sapiens L-FILIP protein.
Length = 1213
Score = 56.8 bits (131), Expect = 4e-07
Identities = 79/440 (17%), Positives = 185/440 (42%), Gaps = 24/440 (5%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LE+ ++LQ+A + E+ + E + E+ L KR+++++ + + + +T +
Sbjct: 344 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQ 403
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ +++ +K++ ++ L + + E++ + + F K +C + + +
Sbjct: 404 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLT 463
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDIVNL 784
K D ++ +++RVK + + K +L + TK K L++ +K + + +
Sbjct: 464 K--DLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 521
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
EE K + L K+ ++ K+E+ + +L I K+
Sbjct: 522 EERK--VDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKL 579
Query: 845 EVAFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQV--LTKKIDTL 901
+ K L + KK+ + E+E+ + D ++ LT +I+ L
Sbjct: 580 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 639
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
K + + EV + D L K + + +++ +K N ++ ++L E + I K
Sbjct: 640 KKRLQQLEVVEGD------LMKTEDEYDQLEQKFRTEQDKANFLS-QQLEEIKHQIAKNK 692
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ +K E +EL+ R LE++ S+D++ + + ++H + + +
Sbjct: 693 AI--EKGEVVSQEAELR-----HRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQ 745
Query: 1022 VALDKCLMEFHREKMENINM 1041
V F E+ +N NM
Sbjct: 746 VDYSVLQQRFMEEENKNKNM 765
Score = 38.3 bits (85), Expect = 0.16
Identities = 103/587 (17%), Positives = 236/587 (40%), Gaps = 50/587 (8%)
Query: 385 KQAENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN 440
K+ EN + + + E+ + + V++ + +++L + K+Q T KL+E+E +
Sbjct: 225 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKA 284
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXX 500
+ +K K+ ++ K +E+ F+ + ++ N+
Sbjct: 285 ITSKSKE-----DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLT 339
Query: 501 XXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E + ++L + EL + DKI K CG S VE L+ + VL+
Sbjct: 340 QRIE-ELEETNKNLQKAEEELQELRDKIAKGECGN-------SSLMAEVENLR--KRVLE 389
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
K + K S C + + E +LEK+ E ++
Sbjct: 390 ME----GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKS 445
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ ++ + +T E+ ++ R+ +++ L + E+++ + K
Sbjct: 446 KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA--ELSLKDDLTKLKS 503
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T + M+++ QE + V + K + G V +DV T K ++ +K+ L
Sbjct: 504 FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-----MDV-TEKLIEESKKLLKL 557
Query: 740 RNRVKTTQKKLNAHNKKL-QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
++ ++ L +L L ++ K+ E + + + +EE ++++
Sbjct: 558 KSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREI------T 611
Query: 799 XXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI 858
P + +KE + + E +++ +E + K E +++++
Sbjct: 612 RGRSRKGSELTCPEDNKIKE-LTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRT 669
Query: 859 QQHKKKNVPREMEKI--QEANDKLMEKQKQIMTDRQVLTK-KIDTLKDEIAKQEV--YKR 913
+Q K + +++E+I Q A +K +EK + + + ++ + +++ K K EV K
Sbjct: 670 EQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKE 729
Query: 914 DLDDNL----CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
+ + + L + Q D + Q++ E K + +E LN + L
Sbjct: 730 KIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKEL 776
Score = 36.7 bits (81), Expect = 0.50
Identities = 83/424 (19%), Positives = 175/424 (41%), Gaps = 27/424 (6%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
HK + EE ++ E Q ++ L+Q+I +L++ L++ E + L+
Sbjct: 305 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRD 364
Query: 444 KEKQLIVLKNKHKTALMELLGNVPE---KDFAVTINKFEC-EVRNEVXXXXXXXXXXXXX 499
K + + + L V E KD +T + +C E+R ++
Sbjct: 365 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 424
Query: 500 XXXLE---AERKHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQ 555
L+ +E + + E+ ++ +SE T+ + K T+ L + V++L+ +
Sbjct: 425 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 484
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRG--FENESEXXXXXXXXXXXXMNVPGKLEKVT 613
+ L+ + + +LK + + R E + GK+ VT
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 544
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E L S K +L +KS + EK+ L E +L ++ + + L+ +V+ + L
Sbjct: 545 EKLIEESKK---LLKLKSEMEEKVYNL-TRERDELIGKLKSEEEKSSELSCSVDLLKKRL 600
Query: 673 --IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
IE ++ T + + +IK +T + E +K++ L+V +
Sbjct: 601 DGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL------QQLEVVEGDLM 654
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK--KTKA--KEELLNTQKKVQDIVNLEE 786
+ + L + +T Q K N +++L+ + + K KA K E+++ + +++ LEE
Sbjct: 655 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEE 714
Query: 787 SKKQ 790
+K +
Sbjct: 715 AKSR 718
>AB033101-1|BAA86589.1| 1140|Homo sapiens KIAA1275 protein protein.
Length = 1140
Score = 56.8 bits (131), Expect = 4e-07
Identities = 79/440 (17%), Positives = 185/440 (42%), Gaps = 24/440 (5%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LE+ ++LQ+A + E+ + E + E+ L KR+++++ + + + +T +
Sbjct: 271 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQ 330
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ +++ +K++ ++ L + + E++ + + F K +C + + +
Sbjct: 331 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLT 390
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDIVNL 784
K D ++ +++RVK + + K +L + TK K L++ +K + + +
Sbjct: 391 K--DLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 448
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
EE K + L K+ ++ K+E+ + +L I K+
Sbjct: 449 EERK--VDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKL 506
Query: 845 EVAFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQV--LTKKIDTL 901
+ K L + KK+ + E+E+ + D ++ LT +I+ L
Sbjct: 507 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 566
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
K + + EV + D L K + + +++ +K N ++ ++L E + I K
Sbjct: 567 KKRLQQLEVVEGD------LMKTEDEYDQLEQKFRTEQDKANFLS-QQLEEIKHQIAKNK 619
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ +K E +EL+ R LE++ S+D++ + + ++H + + +
Sbjct: 620 AI--EKGEVVSQEAELR-----HRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQ 672
Query: 1022 VALDKCLMEFHREKMENINM 1041
V F E+ +N NM
Sbjct: 673 VDYSVLQQRFMEEENKNKNM 692
Score = 38.3 bits (85), Expect = 0.16
Identities = 103/587 (17%), Positives = 236/587 (40%), Gaps = 50/587 (8%)
Query: 385 KQAENELNIEECQQEINEDEK----AVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEEN 440
K+ EN + + + E+ + + V++ + +++L + K+Q T KL+E+E +
Sbjct: 152 KEKENAKRLNKLRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKA 211
Query: 441 LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXX 500
+ +K K+ ++ K +E+ F+ + ++ N+
Sbjct: 212 ITSKSKE-----DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLT 266
Query: 501 XXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
+E E + ++L + EL + DKI K CG S VE L+ + VL+
Sbjct: 267 QRIE-ELEETNKNLQKAEEELQELRDKIAKGECGN-------SSLMAEVENLR--KRVLE 316
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
K + K S C + + E +LEK+ E ++
Sbjct: 317 ME----GKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKS 372
Query: 620 SAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM 679
++ ++ + +T E+ ++ R+ +++ L + E+++ + K
Sbjct: 373 KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKA--ELSLKDDLTKLKS 430
Query: 680 TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
T + M+++ QE + V + K + G V +DV T K ++ +K+ L
Sbjct: 431 FTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV-----MDV-TEKLIEESKKLLKL 484
Query: 740 RNRVKTTQKKLNAHNKKL-QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
++ ++ L +L L ++ K+ E + + + +EE ++++
Sbjct: 485 KSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREI------T 538
Query: 799 XXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI 858
P + +KE + + E +++ +E + K E +++++
Sbjct: 539 RGRSRKGSELTCPEDNKIKE-LTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRT 596
Query: 859 QQHKKKNVPREMEKI--QEANDKLMEKQKQIMTDRQVLTK-KIDTLKDEIAKQEV--YKR 913
+Q K + +++E+I Q A +K +EK + + + ++ + +++ K K EV K
Sbjct: 597 EQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAEVQALKE 656
Query: 914 DLDDNL----CLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESL 956
+ + + L + Q D + Q++ E K + +E LN + L
Sbjct: 657 KIHELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKEL 703
Score = 36.7 bits (81), Expect = 0.50
Identities = 83/424 (19%), Positives = 175/424 (41%), Gaps = 27/424 (6%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
HK + EE ++ E Q ++ L+Q+I +L++ L++ E + L+
Sbjct: 232 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRD 291
Query: 444 KEKQLIVLKNKHKTALMELLGNVPE---KDFAVTINKFEC-EVRNEVXXXXXXXXXXXXX 499
K + + + L V E KD +T + +C E+R ++
Sbjct: 292 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 351
Query: 500 XXXLE---AERKHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQ 555
L+ +E + + E+ ++ +SE T+ + K T+ L + V++L+ +
Sbjct: 352 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 411
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRG--FENESEXXXXXXXXXXXXMNVPGKLEKVT 613
+ L+ + + +LK + + R E + GK+ VT
Sbjct: 412 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 471
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E L S K +L +KS + EK+ L E +L ++ + + L+ +V+ + L
Sbjct: 472 EKLIEESKK---LLKLKSEMEEKVYNL-TRERDELIGKLKSEEEKSSELSCSVDLLKKRL 527
Query: 673 --IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
IE ++ T + + +IK +T + E +K++ L+V +
Sbjct: 528 DGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL------QQLEVVEGDLM 581
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK--KTKA--KEELLNTQKKVQDIVNLEE 786
+ + L + +T Q K N +++L+ + + K KA K E+++ + +++ LEE
Sbjct: 582 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEE 641
Query: 787 SKKQ 790
+K +
Sbjct: 642 AKSR 645
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 56.4 bits (130), Expect = 6e-07
Identities = 142/803 (17%), Positives = 320/803 (39%), Gaps = 63/803 (7%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ S + +K+R D ++ L+ + E V A ++E + K+ F K
Sbjct: 57 EELEEEIEAERTSRA--KAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKKREAEFQK 114
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K I ++
Sbjct: 115 MRRDLEEATLQHEATAATLR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLA 173
Query: 288 TNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXX 347
+N E + K LEK+ D Q S+ +E++ Q +++ + +
Sbjct: 174 SNMETVSKAKGNLEKMCRALED---QLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSR 230
Query: 348 XXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAV 407
T ++ +A++ L Q ++ +
Sbjct: 231 QLDEKDTLE----TQLSRGKQAFTQQIEELKRQLEEEIKAKSAL-AHALQSSRHDCDLLR 285
Query: 408 EQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLG 464
EQYE+E + EL + ++K + A+ + K + +T+E L K K L +
Sbjct: 286 EQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQDAEE 343
Query: 465 NVPEKDF-AVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE--RRSEL 521
+V + ++ K + ++NEV L+ ++ + + L E ++ E
Sbjct: 344 HVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQTNFDKILAEWKQKCEE 403
Query: 522 TKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLC 581
T A + ++ ++ L K E+ D+ L+ + + L +
Sbjct: 404 THAVLESFQK-ESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA---- 458
Query: 582 NRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLNEKIT 637
G + E + LE+ L+ K + E+ +KS ++
Sbjct: 459 -EGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLEVNQVKSEVDRKI 517
Query: 638 TLKDTEIPQLEKRIVDVDTQIK-TLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI 696
KD EI Q+++ + ++ ++ TLN + ++ ++ ++ + +R
Sbjct: 518 AEKDEEIDQMKRNHIRIEESMQSTLNAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 577
Query: 697 QEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK 756
E + +A+ + D+++ LD A Q D K++++ + R Q ++
Sbjct: 578 AEDLRNYQNTQAILK-----DTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRAT 632
Query: 757 LQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPL 812
L+ + A++ELL+ ++VQ + +L +KK+L++D
Sbjct: 633 LEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIKEARNA 692
Query: 813 EVALKEKI---EAKTEVVRRNRDLIEAGSAYIAKVEVAFNK-VKSLDAEIQQHKKKNVPR 868
E K+ I E +++ +D SA++ +++ + VK L + + ++ +
Sbjct: 693 EEKAKKAITDAAMMAEELKKEQDT----SAHLERMKKNLEQTVKDLQHRLDEAEQLALKG 748
Query: 869 EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL--KDEIAKQEVYKRDLDDNLCLR---- 922
++IQ+ K+ E + ++ ++++ + + L + K+ Y+ + D LR
Sbjct: 749 GKKQIQKLEAKVRELEGEVESEQKRNVEAVKGLHKHERKVKELTYQTEEDRKNILRLQDL 808
Query: 923 --KAQTDITNWQKQDDELNEKLN 943
K Q + ++++Q +E E+ N
Sbjct: 809 VDKLQAKVKSYKRQAEEAEEQSN 831
Score = 52.0 bits (119), Expect = 1e-05
Identities = 123/679 (18%), Positives = 258/679 (37%), Gaps = 71/679 (10%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQKI------TKLQKQTAKL 431
K E + IEE ++EI + EK +E++E+S+++ T Q + K
Sbjct: 48 KIKELQARIEELEEEIEAERTSRAKAEKLRSDLSRELEEISERLEEAVGATSTQIEMNKK 107
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E L+ KH ++ EL + + + K + E++
Sbjct: 108 REAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKM 167
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + L+E + TK E++ L +
Sbjct: 168 EIDDLASNMETVSKAKGNLEKMCRALEDQLSEIK---TKEEEQQRLINDLTAQRARLQQN 224
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
+ DE++ L++ + +G+ R E E + +
Sbjct: 225 QVEYSRQLDEKDTLETQL-----SRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRH 279
Query: 605 VPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET 664
L + E+ Q A A+ +M N ++ + K D + + L E
Sbjct: 280 DCDLLREQYEEEQEAKAELQR--AMSKANSEVAQWR-------TKYETDAIQRTEELEEA 330
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ-EIKTVTKKFEAVKEQCGDVDSEMTLD 723
+++ L + E+ + + + +Q E++ + E C +D
Sbjct: 331 KKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDK----- 385
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
KQ +F + ++ + + + T L + K+ ++L + K K ++ + +
Sbjct: 386 ----KQTNFDKILAEWKQKCEETHAVLESFQKESRSLSTELFKIKNAY---EESLDQLET 438
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
L+ K LQ + I LE K+ + K+E+ + +E A +
Sbjct: 439 LKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSEL----QAALEEAEASLEH 494
Query: 844 VEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQ-VLTKKIDTLK 902
E K+ + E+ Q K V R++ + E D++ +I Q L +I +
Sbjct: 495 EE---GKILRIQLEVNQ-VKSEVDRKIAEKDEEIDQMKRNHIRIEESMQSTLNAEIRSRN 550
Query: 903 DEIAKQEVYKRDLDD-----NLCLRKAQTDITNWQK-----QDDELNEKLNGINKEELNE 952
D I ++ + DL++ N R A D+ N+Q +D +L+ ++E+L E
Sbjct: 551 DAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILKDTQLHLDDALRSQEDLKE 610
Query: 953 KESLIIKQTKLFQQK-AECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTK 1011
+ +++ ++ L Q + E L + ++S K EL S+ ++ + ++ K
Sbjct: 611 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQEL-LDASERVQLLHTQNTSLINTKK 669
Query: 1012 AIDKDIREYAVALDKCLME 1030
++ DI + ++ + E
Sbjct: 670 KLETDISQIQGEMEDIIKE 688
Score = 43.2 bits (97), Expect = 0.006
Identities = 74/396 (18%), Positives = 179/396 (45%), Gaps = 39/396 (9%)
Query: 612 VTEDLQRASAK-KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITM 670
+ D Q+ K K + M L KI + + QL+K+I ++ +I+ L E +E
Sbjct: 10 IENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGM-QLQKKIKELQARIEELEEEIEAERT 68
Query: 671 SLIEPEQ-KMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ 729
S + E+ + ++++ + +R + + + + E K++ + +M D+ A
Sbjct: 69 SRAKAEKLRSDLSRELE---EISERLEEAVGATSTQIEMNKKREAEF-QKMRRDLEEA-T 123
Query: 730 VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEESK 788
+ + +TLR + + +L LQ + +K K K E+ + ++ + ++K
Sbjct: 124 LQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAK 183
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
L+ C LE L E I+ K E +R + + A A + + +V +
Sbjct: 184 GNLEKMCRA--------------LEDQLSE-IKTKEEEQQRLINDLTAQRARLQQNQVEY 228
Query: 849 NK----VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
++ +L+ ++ + K+ +++E+++ ++ ++ + + Q D L+++
Sbjct: 229 SRQLDEKDTLETQLSRGKQA-FTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQ 287
Query: 905 IAKQEVYKRDLDDNLCLRKAQTDITNWQ-KQDDELNEKLNGINKEELNEKESLIIKQTKL 963
+++ K +L + KA +++ W+ K + + ++ EEL E + + ++ +
Sbjct: 288 YEEEQEAKAEL--QRAMSKANSEVAQWRTKYETDAIQR-----TEELEEAKKKLAQRLQD 340
Query: 964 FQQKAECTGA-LSELKKSLKGFRNELEKSLSKDIEK 998
++ E A + L+K+ + +NE+E L D+E+
Sbjct: 341 AEEHVEAVNAKCASLEKTKQRLQNEVE-DLMIDVER 375
>BX538186-1|CAD98058.1| 971|Homo sapiens hypothetical protein
protein.
Length = 971
Score = 56.4 bits (130), Expect = 6e-07
Identities = 104/504 (20%), Positives = 220/504 (43%), Gaps = 41/504 (8%)
Query: 549 EKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGK 608
+KLQ + ++++ ++ K K+ L ++ E ESE ++ K
Sbjct: 204 QKLQTALAIAENNVQVLQKQLDDAKEGEMA-LLSKHKEVESELAAARERLQQQASDLVLK 262
Query: 609 LEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+ + +A+ E+ ++K L + + + + + QLE+ + ++ ++L+E E
Sbjct: 263 ASHI--GMLQATQMTQEV-TIKDLESEKSRVNE-RLSQLEEERAFLRSKTQSLDE---EQ 315
Query: 669 TMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAK 728
++E E+K+ AK+ + Y +E+K + + E Q + S+ ++A
Sbjct: 316 KQQILELEKKVNEAKRTQQEY-----YERELKNLQSRLEEEVTQLNEAHSKTLEELAWKH 370
Query: 729 QVDFKQKIST-LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
+ + S +R++ K HNK L E K + ++EL N ++ ++D ++
Sbjct: 371 HMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLDTANQ 430
Query: 788 K-KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
+ LQ I L+ + +E+++ + ++ + + L E A +
Sbjct: 431 EIGHLQDMVRKSEQGLGSAEGLIASLQDS-QERLQNELDLTKDS--LKETKDALL----- 482
Query: 847 AFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
N L+ E QQH++ +E EK++ DK+ + T+ L ++ L++E+
Sbjct: 483 --NVEGELEQERQQHEETIAAMKEEEKLKV--DKMAHDLEIKWTEN--LRQECSKLREEL 536
Query: 906 AKQ--EVYKRDLDDNLCLRKAQTDIT--NWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
Q E K + L L+ + + +WQK+ ++L LN I+ + N + L QT
Sbjct: 537 RLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDL---LNQISLLKQNLEIQLSQSQT 593
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELE---KSLSKDIEKKFREKMYELH-VTKAIDKDI 1017
L Q +A+ T L + L+ + + KSL + F+ E +A++ +
Sbjct: 594 SLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKEKEQRALENHL 653
Query: 1018 REYAVALDKCLMEFHREKMENINM 1041
++ A + L + HRE ME + +
Sbjct: 654 QQKHSAELQSLKDAHRESMEGLRI 677
Score = 39.5 bits (88), Expect = 0.071
Identities = 159/850 (18%), Positives = 321/850 (37%), Gaps = 77/850 (9%)
Query: 182 FDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNT-SFNKEEEKIA 240
F+ DK D R++ + LK ++++ +V Q++ E+ ++ S NK E++
Sbjct: 59 FEKDKRLALEDLQAAHRREIQELLKSQQDHSASVNKGQEKAEELHRMEVESLNKMLEELR 118
Query: 241 NEKSSNEIEYN-KFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTI 299
E+ +Y K +S + ++D + TA+ + E +E + +
Sbjct: 119 LERKKLIEDYEGKLNKAQSFYERELDTLKRSQLFTAESLQASKEKEADLRKEFQGQEAIL 178
Query: 300 LEKVESLKSDHKVQKSQADEEEKKAQGFVDECR--SGHTQXXXXXXXXXXXXXXXXXXXX 357
+ + LK++ ++ + +A K Q + Q
Sbjct: 179 RKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAIAENNVQVLQKQLDDAKEGEMALLSKH 238
Query: 358 XDITSANQSXXXXXXXXXXXXXXXXXH------KQAENELNIEECQ---QEIN------E 402
++ S + H Q E+ I++ + +N E
Sbjct: 239 KEVESELAAARERLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEKSRVNERLSQLE 298
Query: 403 DEKA-VEQYEQEMD-ELSQKITKLQKQT--AKLKEKEMIEENLKT----KEKQLIVLKNK 454
+E+A + Q +D E Q+I +L+K+ AK ++E E LK E+++ L
Sbjct: 299 EERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEA 358
Query: 455 HKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESL 514
H L EL AV N +R++ LE ++ +++ L
Sbjct: 359 HSKTLEELAWKHHMAIEAVHSN----AIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQEL 414
Query: 515 NERRSELTKAEDKIYKACG-----TQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ L D + G + + L + LQD Q LQ+ + +
Sbjct: 415 ENLKEVLEDKLDTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSL 474
Query: 570 GQLKD---NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLE-KVTEDLQRASAKKDE 625
+ KD N L ++E + LE K TE+L++ +K E
Sbjct: 475 KETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEIKWTENLRQECSKLRE 534
Query: 626 ILSM------KSLNEKITTLKDTE----IPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
L + KS ++ LKD E +K++ D+ QI L + +E I+
Sbjct: 535 ELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQNLE------IQL 588
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK 735
Q T+ +Q+ ++ QE + +T++ E ++EQ + A Q ++K
Sbjct: 589 SQSQTSLQQLQA------QFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEK 642
Query: 736 ISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDI-VNLEESKKQLQS 793
R Q+K H+ +LQ+L + ++ E L + ++++Q + LE+ K + +
Sbjct: 643 EKEQRALENHLQQK---HSAELQSLKDAHRESMEGLRIEMEQELQTLRFELEDEGKAMLA 699
Query: 794 DCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGS-AYIAKVEVAFNKVK 852
AI L +++ A + R+ D+ S +I ++ +++
Sbjct: 700 --SLRSELNHQHAAAIDLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQEELR 757
Query: 853 SLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYK 912
+ I + K V E I +L K K+I+ R ++I +E+ ++ + +
Sbjct: 758 HREHRISE-LDKEVQHLHENISALTKELEFKGKEILRIRSESNQQIRL--EEMEEKYLMR 814
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
+++ + T++ + D++ +KL NK E + K+F + G
Sbjct: 815 ESKPEDI---QMITELKAMLTERDQIIKKLIEDNKFYQLELVNRETNFNKVF-NSSPTVG 870
Query: 973 ALSELKKSLK 982
++ L K K
Sbjct: 871 VINPLAKQKK 880
Score = 37.9 bits (84), Expect = 0.22
Identities = 72/400 (18%), Positives = 172/400 (43%), Gaps = 32/400 (8%)
Query: 617 QRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD-TQIKTLNETVEEITMSLIEP 675
+R S ++E ++S + + + +I +LEK++ + TQ + ++ + L
Sbjct: 292 ERLSQLEEERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRL--- 348
Query: 676 EQKMTTAKQIHGDM--PMLDRYIQEIKTV-TKKFEAVKEQCGDVDSEMTLDVATAKQVDF 732
E+++T + H + ++ I+ V + K+ D++ + D ++ D
Sbjct: 349 EEEVTQLNEAHSKTLEELAWKHHMAIEAVHSNAIRDKKKLQMDLEEQHNKDKLNLEE-DK 407
Query: 733 KQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQ 792
Q L N + + KL+ N+++ L + K+++ L + + I +L++S+++LQ
Sbjct: 408 NQLQQELENLKEVLEDKLDTANQEIGHLQDMVRKSEQGLGSAEGL---IASLQDSQERLQ 464
Query: 793 SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK 852
++ A+ +E L+++ + E + ++ + +A ++ +
Sbjct: 465 NELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAH-DLEIKWTE 523
Query: 853 SLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA--KQE 909
+L E + +++ + E +K + L K ++ R KK++ L ++I+ KQ
Sbjct: 524 NLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAARDSWQKKVEDLLNQISLLKQN 583
Query: 910 VYKRDLDDNLCLRKAQTDITNWQK----QDDELNEKLNGINK-------------EELNE 952
+ + L++ Q T ++ + +EL E+ +K EE E
Sbjct: 584 LEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQRHKSLKEAHVLAFQTMEEEKE 643
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL 992
KE ++ + AE ++S++G R E+E+ L
Sbjct: 644 KEQRALENHLQQKHSAELQSLKDAHRESMEGLRIEMEQEL 683
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 56.4 bits (130), Expect = 6e-07
Identities = 134/725 (18%), Positives = 304/725 (41%), Gaps = 59/725 (8%)
Query: 386 QAENEL---NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLK 442
QAE E+ N+ C++E ++ Y+ E++ L +K+ +L+++ KEK I +
Sbjct: 12 QAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRI---MA 68
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
K +++ + + ++++L + KD + +KF N
Sbjct: 69 VKNSEVMAQLTESRQSILKLESELENKD-EILRDKFSLMNENRELKVRVAAQNERLDLCQ 127
Query: 503 LEAERKHIR-ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNV--LQ 559
E E + SL + S+L + G + Y LSKY + ++++ + +
Sbjct: 128 QEIESSRVELRSLEKIISQLPLKRELF----GFKSY---LSKYQMSSFSNKEDRCIGCCE 180
Query: 560 SSMFIIN--KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL- 616
++ +I+ + K +K+ L N+ + LE L
Sbjct: 181 ANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKL-SSLETEPVKLG 239
Query: 617 --QRASAKKDEIL-SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT--MS 671
Q A + KD+ +M EK T I +L +++ ++ + L + T
Sbjct: 240 GHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQ 299
Query: 672 LIEPE--QKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ 729
LI+ E +K + + ++ +M + ++ T+ K+ E + + AK
Sbjct: 300 LIQEELLEKASNSSKLESEM---TKKCSQLLTLEKQLE---------EKIVAYSSIAAKN 347
Query: 730 VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAK-EELLNTQKKVQDI-VNLEES 787
+ +Q++ ++++ + +N ++K+ +EK K E+ +K+++ + LE+
Sbjct: 348 AELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKK 407
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+Q + LE + E+K E+ + N EA A +V
Sbjct: 408 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEE 467
Query: 848 FNKVKSLDAEIQQHKKKNV--PREMEKIQEANDK-LMEKQKQIMTDRQVLTKKIDTLKDE 904
KV+ LD+ ++ K++ V ++E +E +K L +K +++ ++ L K +L++
Sbjct: 468 TIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQET 527
Query: 905 IAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDE--LNEKLNGINKEELNEKESLIIKQTK 962
+ + + L + + +T I N + +D + L ++++ + +E ++ES K K
Sbjct: 528 SEQNVILQHTLQQQQQMLQQET-IRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRK 586
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAV 1022
+ ++K E ++LK R ++ + + K Y+ ++K ++K+I +
Sbjct: 587 M-EEKCESAAHEADLK------RQKVIELTGTARQVKIEMDQYKEELSK-MEKEIMH--L 636
Query: 1023 ALDKCLMEFHREKMENI-NMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVV 1081
D H +++ I + EL +K +++ ++ TE LT ++R+ +
Sbjct: 637 KRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETEL 696
Query: 1082 QSKNG 1086
Q+ +G
Sbjct: 697 QNAHG 701
Score = 49.6 bits (113), Expect = 7e-05
Identities = 116/634 (18%), Positives = 261/634 (41%), Gaps = 50/634 (7%)
Query: 385 KQAEN-ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
KQ E E +E+ Q+ E EK + +Q++ + L + + K EM +EN+K
Sbjct: 395 KQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKG-EMKKENMK- 452
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
K++ L L+N+ + E V + D A+ I K E + +
Sbjct: 453 KDEALKALQNQ----VSEETIKVRQLDSALEICKEELVLH--LNQLEGNKEKFEKQLKKK 506
Query: 504 EAERKHIRESLNERRSELTK-AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
E +++ L + L + +E + Q L + T +L+D Q L+ +
Sbjct: 507 SEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQV 566
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXM-NVPGKLEKVTEDL----Q 617
+ + + +++S L R E + E + + G +V ++ +
Sbjct: 567 SKLEQELQKQRESSAEKL--RKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKE 624
Query: 618 RASAKKDEILSMKSLNE-------KITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITM 670
S + EI+ +K E ++ + D +LEK+ V K + T E+T
Sbjct: 625 ELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTE 684
Query: 671 SLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ- 729
+L + E T + HG++ R +QE++ V +K + E+ ++T ++ K
Sbjct: 685 ALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKME 744
Query: 730 -VDFKQKISTLRNRVKTTQKKLNAHNKKL----QTLYEKKTKAKEELLNTQKKVQ-DIVN 783
D KQ++ + +K +L ++ T+ E + + +++++ + ++ +
Sbjct: 745 IEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELE 804
Query: 784 LEESKKQLQS--DCXXXXXXXXXXXXAI---TPLEVA-LKEKIEAKTEVVRRNRDLIEAG 837
L+E KQ++S D I E++ LK++IE + ++ +++
Sbjct: 805 LKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQ 864
Query: 838 SAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK 897
YIA + + L E++ ++ V ++ EA + ++ Q++I + L+ +
Sbjct: 865 EQYIA---TQYKEAIDLGQELRL-TREQVQNSHTELAEARHQQVQAQREI----ERLSSE 916
Query: 898 IDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLI 957
++ +K +++ + L + L K + + + ++ ++ E + KE+
Sbjct: 917 LEDMKQLSKEKDAHGNHLAEELGASKVRE-----AHLEARMQAEIKKLSAEVESLKEAYH 971
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
++ + A+ + K S++ +LEK+
Sbjct: 972 MEMISHQENHAKWKISADSQKSSVQQLNEQLEKA 1005
Score = 47.2 bits (107), Expect = 4e-04
Identities = 116/693 (16%), Positives = 275/693 (39%), Gaps = 43/693 (6%)
Query: 105 LAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDS 164
L +K K ++L++ ++T E K + + + H+E+ K I ++D
Sbjct: 354 LMEKNEKIRSLETNINTEHE--KICLAFEKAKKIHLEQHKEM--EKQIERLEAQLEKKDQ 409
Query: 165 SWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELED 224
+ E K + +I + + LDRL K + + ++ A +KA Q ++ +
Sbjct: 410 QFKEQE-KTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEA--LKALQNQVSE 466
Query: 225 SYKKNTSFNKEEEKIANEK--SSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIEN 282
K + E E N++E NK + ++++ K++E++ K +I+N
Sbjct: 467 ETIKVRQLDSALEICKEELVLHLNQLEGNK-----EKFEKQLKKKSEEVYCLQKELKIKN 521
Query: 283 ITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXX 342
+ +T+E+ T+ ++ + L+ + ++ + ++ + K + V + +
Sbjct: 522 HSLQETSEQNVILQHTLQQQQQMLQQE-TIRNGELEDTQTKLEKQVSKLEQELQKQRESS 580
Query: 343 XXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINE 402
+ Q +K+ +++ E + +
Sbjct: 581 AEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDG 640
Query: 403 DEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMEL 462
+ KA+ + +M L Q T+L+K+T +KE E ++ + +T+ + + + +T L
Sbjct: 641 ENKAMHLSQLDMI-LDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNA 699
Query: 463 LGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
G + T+ + + E+R+ + L AE + + + +++ EL
Sbjct: 700 HGELKS-----TLRQLQ-ELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELL 753
Query: 523 KAEDKIYK---ACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD-NSCC 578
+ + + + + VT T + + EQ +++ + K + +LK+ N
Sbjct: 754 EMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLE-GTLEKSELELKECNKQI 812
Query: 579 PLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITT 638
N +N E + ++ ++ ++++R + E+ S+ E+
Sbjct: 813 ESLNDKLQNAKE---QLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIA 869
Query: 639 LKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDR---- 694
+ E L + + Q++ + + E ++ ++++ DM L +
Sbjct: 870 TQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDA 929
Query: 695 ---YIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
++ E +K EA E + +++ +V + K+ + IS N K K+
Sbjct: 930 HGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKW---KI 986
Query: 751 NAHNKK--LQTLYEKKTKAKEELLNTQKKVQDI 781
+A ++K +Q L E+ KAK EL Q V ++
Sbjct: 987 SADSQKSSVQQLNEQLEKAKLELEEAQDTVSNL 1019
>AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-1
protein.
Length = 795
Score = 56.4 bits (130), Expect = 6e-07
Identities = 93/406 (22%), Positives = 184/406 (45%), Gaps = 50/406 (12%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+L+ +T +LQ+ S++ +E+ K+T K+ E+ +L+K + + +T + N+ E+
Sbjct: 404 QLKILTMELQKKSSELEEMT-------KLTNNKEVELEELKKVLGEKETLLYE-NKQFEK 455
Query: 668 ITMSLIEPEQKM-----TTAKQIHGDMPMLDR-------YIQEIKTVTKKFEAVKEQCGD 715
I L EQ++ K++H L Y +E+K + K E E+ +
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL--KTELENEKLKN 513
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
+ + + + + Q+ S + +K Q+ +N +NKK + E+ K E L T+
Sbjct: 514 TELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN-NNKKQE---ERMLKQIENLQETE 569
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
++++ LE +++L+ L ++ K + E+ + N+ L +
Sbjct: 570 TQLRN--ELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKK 627
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREME--KIQEAN-DKLMEKQKQ 886
G+A ++ V KV L+ E++ K+K +E+E KI E N + +EK K
Sbjct: 628 KGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKV 687
Query: 887 IMTDRQVLTKKID-----TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD----- 936
I + L K+ID + + +A E +K D + R ++ + ++Q+
Sbjct: 688 IADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRA 747
Query: 937 ELNEKLNGINKEELNEKESLII---KQTKLFQQKAECTGALSELKK 979
L +L+ + E L+ K+ L I ++ KL ++ E T L E KK
Sbjct: 748 SLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKK 793
Score = 39.9 bits (89), Expect = 0.054
Identities = 53/231 (22%), Positives = 106/231 (45%), Gaps = 20/231 (8%)
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK-SLDAEIQQH----KKKNVP 867
+V+ + ++ K ++ NR +IEA I +++ KV L+ IQ++ K+ N
Sbjct: 120 KVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNAT 179
Query: 868 REM-EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
R + ++E + EK K+ +R+ + L + I K +L + ++
Sbjct: 180 RHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEEL--RVQAENSRL 237
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKES----LIIKQTKLFQQKAECTGALSELKKSLK 982
++ K+D E + L K+E+N+KE L+I+ T+ + + T L E + +
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV- 296
Query: 983 GFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR---EYAVALDKCLME 1030
N+LE+ E + + H+TK ++ DI+ + +V+ K L E
Sbjct: 297 ---NQLEEKTKLQSENLKQSIEKQHHLTKELE-DIKVSLQRSVSTQKALEE 343
Score = 39.9 bits (89), Expect = 0.054
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 211 YATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQ 270
Y+ VK + ELE+ KNT K++ E E + + LE +NQ++ D N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD-MTLELKNQQE-DINNNK 552
Query: 271 IVETAKIAEIENI--TEVQTNEEAENATKTILEKVESLKSDHKVQKSQ 316
E + +IEN+ TE Q E E + + +K + +K K+ KS+
Sbjct: 553 KQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKC--KLDKSE 598
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 56.0 bits (129), Expect = 8e-07
Identities = 91/419 (21%), Positives = 188/419 (44%), Gaps = 50/419 (11%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 915 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 974
Query: 656 TQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
++K L E + +EI L + ++ + A Q D + ++ T++K +++Q
Sbjct: 975 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLSKSKVKLEQQ 1032
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKK-LNAHNKKLQTLYEKKTKAKEEL 771
D++ +L+ ++D ++ L +K TQ+ ++ N KLQ E+K K KE
Sbjct: 1033 VDDLEG--SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQ--LEEKLKKKEFD 1088
Query: 772 LNTQ-KKVQD--IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+N Q K++D ++ L+ KK ++ +V K + + E+
Sbjct: 1089 INQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVE-KLRSDLSRELEE 1147
Query: 829 RNRDLIEAGSAYIAKVEV------AFNKV-KSLDAEIQQH-------KKKN------VPR 868
+ L EAG A ++E+ F K+ + L+ QH +KK+ +
Sbjct: 1148 ISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGE 1207
Query: 869 EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD-----NLCLRK 923
+++ +Q KL +++ + + +T ++ + A E R L+D + L +
Sbjct: 1208 QIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEE 1267
Query: 924 AQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
AQ + ++ Q +L + NG +L EKE+LI ++L + K T + +LK+ L+
Sbjct: 1268 AQRSLNDFTTQRAKLQTE-NGELSRQLEEKEALI---SQLTRGKLSYTQQMEDLKRQLE 1322
Score = 53.2 bits (122), Expect = 5e-06
Identities = 132/727 (18%), Positives = 290/727 (39%), Gaps = 76/727 (10%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQKI------TKLQKQTAKL 431
K EN+ IEE ++E+ + EK +E++E+S+++ T +Q + K
Sbjct: 1109 KLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKK 1168
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E L+ KH ++ EL + + + K + E +
Sbjct: 1169 REAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 1228
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + NE R +L +A+ + D T +
Sbjct: 1229 ELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSL--------NDFTTQRA 1280
Query: 545 TTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMN 604
E + + + + I +G+L R E E + +
Sbjct: 1281 KLQTENGELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARH 1340
Query: 605 ----VPGKLEKVTE---DLQRASAK-KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDT 656
+ + E+ TE +LQR +K E+ ++ E + E+ + +K++
Sbjct: 1341 DCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELEEAKKKLAQ--- 1397
Query: 657 QIKTLNETVEEITMSLIEPEQ-KMTTAKQIHGDMPMLDRYIQEIKTVTKK---FEAVKEQ 712
+++ E VE + E+ K +I M ++R + KK F+ + +
Sbjct: 1398 RLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1457
Query: 713 CGD--VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
+S+ L+ + + ++ L+N + + + L ++ + L E+ + E+
Sbjct: 1458 WKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQ 1517
Query: 771 LLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE-KIEAKTE 825
L K V ++ LE K +LQS I ++ + K E + +
Sbjct: 1518 LGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1577
Query: 826 VVRRNRDLIEAGSAY---IAKVEVAFNKVKSLDAEIQQHKKK--NVPREME-KIQEANDK 879
+ ++ ++ +A + + ++ + + E+ + KKK EME ++ AN
Sbjct: 1578 LAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRM 1637
Query: 880 LMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL---DDNLCLRKAQTDITNWQKQDD 936
E QKQ+ + + +L L D + + K ++ + L +A+ + +
Sbjct: 1638 AAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQT 1697
Query: 937 ELNEKLNGINKEELNEKESLIIKQ-TKLFQQK----AECTGALSELKKSLKGFRNELEKS 991
E + KL E +E+ L+ Q T L QK A+ + SE++++++ RN EK+
Sbjct: 1698 ERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQECRNAEEKA 1757
Query: 992 ---------LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKC---LMEFHREKMENI 1039
++++++K+ + + K +++ I++ LD+ ++ +++++ +
Sbjct: 1758 KKAITHAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKL 1817
Query: 1040 NMIIREL 1046
+REL
Sbjct: 1818 EARVREL 1824
Score = 52.0 bits (119), Expect = 1e-05
Identities = 155/853 (18%), Positives = 338/853 (39%), Gaps = 83/853 (9%)
Query: 168 LDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSY 226
L E + E +E +A++ + +++K+R D ++ L+ + E A ++E +
Sbjct: 1110 LKENQARIEELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNK 1167
Query: 227 KKNTSFNK-----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAE 279
K+ F K EE + +E ++ + K ++ E+ID +R +Q +E K
Sbjct: 1168 KREAEFQKMRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEF 1226
Query: 280 IENITEVQTNEEAENATKTILEKVE-SLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQX 338
+ +V +N E K LEKV +L+ + + +E ++ F + T+
Sbjct: 1227 KLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTEN 1286
Query: 339 XXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQ 398
++ Q +A+N L Q
Sbjct: 1287 GELSRQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEG--------KAKNAL-AHALQS 1337
Query: 399 EINEDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKH 455
++ + EQYE+E + EL + ++K + A+ + K + +T+E + +
Sbjct: 1338 ARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQRTEELE------EA 1391
Query: 456 KTALMELLGNVPEKDFAV-----TINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
K L + L + E AV ++ K + ++NE+ L+ ++++
Sbjct: 1392 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1451
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQD--EQNVLQSSMFIINKY 568
+ L E + + +++ ++ + Q +LS T + KL++ E+++ F
Sbjct: 1452 DKILAEWKQKYEESQSELESS---QKEARSLS---TELFKLKNAYEESLEHLETFKRENK 1505
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KD 624
Q + + G +N E + + LE+ L+ K +
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMT-TAK 683
E +K+ E+ KD E+ Q ++ V ++T + ++ ++KM
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 684 QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRV 743
++ + +R E + K +++ + D+++ LD A D K+ I+ + R
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLK-----DTQIQLDDAVRANDDLKENIAIVERRN 1680
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXX 799
Q +L ++ + A EL+ T ++VQ + +L KK++ +D
Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLINQKKKMDADLS--- 1737
Query: 800 XXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQ 859
L+ ++E + R + + + A + K + A ++
Sbjct: 1738 ---------------QLQSEVEEAVQECRNAEEKAKKAITHAAMMAEELKKEQDTSAHLE 1782
Query: 860 QHKKKNVPREMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDN 918
+ KKN+ + ++ +Q D+ + K Q L ++ L+ E+ ++ KR+ +
Sbjct: 1783 R-MKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQ--KRNAESV 1839
Query: 919 LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELK 978
+RK++ I Q +E +K N + ++L +K L +K K ++AE A + L
Sbjct: 1840 KGMRKSERRIKELTYQTEE--DKKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLS 1896
Query: 979 KSLKGFRNELEKS 991
K K ++EL+++
Sbjct: 1897 KFRK-VQHELDEA 1908
Score = 41.9 bits (94), Expect = 0.013
Identities = 66/360 (18%), Positives = 149/360 (41%), Gaps = 30/360 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
+ EK + + + + ET+E+ E E+KM + Q D+ +
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDL---------------Q 890
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQK---KLNAHNKKLQTLYE 762
+ EQ D+E D ++ + K+ + R++ ++ +L A +KL+
Sbjct: 891 LQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECS 950
Query: 763 KKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEA 822
+ K ++L T KV+ + E+K + + +T + AL+E +
Sbjct: 951 ELKKDIDDLELTLAKVEKEKHATENKVK---NLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 823 KTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQ-EANDKL- 880
+ ++ D + S K+E +V L+ ++Q KK + E K + E + KL
Sbjct: 1008 ALDDLQAEEDKVNTLSKSKVKLE---QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1064
Query: 881 MEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE 940
E + D+ L +K+ + +I +Q + D+ + + Q + Q + +EL E
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQN--SKIEDEQVLALQLQKKLKENQARIEELEE 1122
Query: 941 KLNG--INKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+L + ++ + S + ++ + ++ E G + ++ + R + + +D+E+
Sbjct: 1123 ELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1182
Score = 33.9 bits (74), Expect = 3.5
Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 6/162 (3%)
Query: 170 EGKKVKERFDEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKK 228
E K ++E + D D ++ L K + Q + LE K + +LE + +K
Sbjct: 997 EKKALQEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRK 1056
Query: 229 -NTSFNKEEEKIA---NEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENIT 284
+E I N+K E + K +Q KI+ ++ K + EN
Sbjct: 1057 LEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLK-ENQA 1115
Query: 285 EVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQG 326
++ EE A +T KVE L+SD + + E ++A G
Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 1157
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 56.0 bits (129), Expect = 8e-07
Identities = 93/526 (17%), Positives = 216/526 (41%), Gaps = 40/526 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
+N++ I++ Q+ + + +K +E E E +L ++ + + L E I EN ++
Sbjct: 426 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTE-ISENSSDLSQK 484
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAV----TINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L ++K++ A+ E+L + + +++ + V
Sbjct: 485 LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALE 544
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL----Q 559
E+ER +E + E +L + E + Y+ S Y + +E + E+ L Q
Sbjct: 545 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQ 602
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT----ED 615
+ I K K LK + E+ E ++ +L K ED
Sbjct: 603 EAQEEIMKLKDTLKSQMTQEASDEA-EDMKEAMNRMIDELNKQVSELSQLYKEAQAELED 661
Query: 616 LQRASAKKDEILSM--KSLNEKITTLKD----------TEIPQLEKRIVDVDTQIKTLNE 663
++ + +D K+ +EK+ L + +E+ ++++ TQ+K L +
Sbjct: 662 YRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVD 721
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
+E ++S+ E Q +TT + +M ++E +K+ E K + ++ + +
Sbjct: 722 AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKE-HLASKEVEVAKLEKQLLEEKAAMT 780
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
A + +++ S+L + V KL K+ + ++ + + + E+ +++ ++I
Sbjct: 781 DAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQT 840
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD-LIEAGSAYIA 842
L +SK+Q ++ E+A ++ + + ++D I S +
Sbjct: 841 LLKSKEQEVNELLQKFQQAQE--------ELAEMKRYSESSSKLEEDKDKKINEMSKEVT 892
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPRE--MEKIQEANDKLMEKQKQ 886
K++ A N + L K+++ E +++++ ++L E +KQ
Sbjct: 893 KLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQ 938
Score = 54.4 bits (125), Expect = 2e-06
Identities = 90/470 (19%), Positives = 209/470 (44%), Gaps = 55/470 (11%)
Query: 608 KLEKVTEDLQR----ASAKKDEI-LSMKSLNEKITTLKDTEIPQ----LEKRIVDVDTQ- 657
+L+++ +DLQ+ + A++ ++ + ++S ++ L +TEI + L +++ + ++
Sbjct: 433 QLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKY 492
Query: 658 ---IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI----QEIKTVTKKFEAVK 710
+K + +++ + L+ PE M H ++ + + I Q+++ ++ E K
Sbjct: 493 EEAMKEVLSVQKQMKLGLVSPES-MDNYSHFH-ELRVTEEEINVLKQDLQNALEESERNK 550
Query: 711 EQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
E+ +++ ++ V K K + + + NK+ L+EK +A+EE
Sbjct: 551 EKVRELEEKL---VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEE 607
Query: 771 LLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
++ + ++ + +E+ + + ++ L KE +A+ E R+
Sbjct: 608 IMKLKDTLKSQMT-QEASDEAEDMKEAMNRMIDELNKQVSELSQLYKE-AQAELEDYRKR 665
Query: 831 RDLIEAGSAYIAKVE-------VAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+ L + + YI K E ++ K+ DA + + V E+ ++++ D E
Sbjct: 666 KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKE 725
Query: 883 KQKQIMTDRQVLT----------KKIDTLKDEIAKQEVYKRDLDDNLCLRK-AQTDI--- 928
I QV+T +KI LK+ +A +EV L+ L K A TD
Sbjct: 726 NSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVP 785
Query: 929 -TNWQKQDDELNEKLNGIN---KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
++++K L +++ + KE + EKE + +++ Q ++E + E K++++
Sbjct: 786 RSSYEKLQSSLESEVSVLASKLKESVKEKEKV---HSEVVQIRSEVSQVKRE-KENIQTL 841
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
E+ ++ ++ +KF++ EL K + + DK + E +E
Sbjct: 842 LKSKEQEVN-ELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKE 890
Score = 33.5 bits (73), Expect = 4.7
Identities = 42/202 (20%), Positives = 90/202 (44%), Gaps = 9/202 (4%)
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKI 898
++ ++ V ++ L ++Q +++ R EK++E +KL+E++K + V ++
Sbjct: 520 SHFHELRVTEEEINVLKQDLQNALEES-ERNKEKVRELEEKLVEREKGTVIKPPV--EEY 576
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE-KESLI 957
+ +K + + + K Q K D L ++ +E + KE++
Sbjct: 577 EEMKSSYC-SVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMN 635
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGF--RNELEKSLSKDIEKKFREKMYEL-HVTKAID 1014
+L +Q +E + E + L+ + R LE ++ I K EK+ +L +V++A
Sbjct: 636 RMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKA 695
Query: 1015 KD-IREYAVALDKCLMEFHREK 1035
+D + E K L E + K
Sbjct: 696 EDALSEMKSQYSKVLNELTQLK 717
Score = 32.7 bits (71), Expect = 8.2
Identities = 17/76 (22%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 385 KQAENELNIEECQ-QEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
+ +E+ +EE + ++INE K V + ++ ++ LSQ + ++ E +++ +K
Sbjct: 868 RYSESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQ 927
Query: 444 KEKQLIVLKNKHKTAL 459
+ QL K +H+ +
Sbjct: 928 LQNQLAECKKQHQEVI 943
>BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosophila)
protein.
Length = 728
Score = 56.0 bits (129), Expect = 8e-07
Identities = 93/417 (22%), Positives = 192/417 (46%), Gaps = 50/417 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILS-MKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+L++ E+LQ A A+K+E+ + L+ ++TTL+D EK + + ++ +NE ++
Sbjct: 179 QLKRALEELQEALAEKEELRQRCEELDMQVTTLQD------EKNSLVSENEM--MNEKLD 230
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++ S +P + K H + +++++ + EA K+ D + +
Sbjct: 231 QLDGSFDDP-NTVVAKKYFHAQL-----QLEQLQEENFRLEAAKD-----DYRVHCEELE 279
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
+ ++F+ + L + + T + L L+ +K K + + ++K+QD+ +L +
Sbjct: 280 KQLIEFQHRNDELTSLAEET-RALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRK 338
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGSAYIAK 843
K LQ LE LK+ A+T++ R+ +DL S+ +
Sbjct: 339 QVKTLQE-------TNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKR 391
Query: 844 VEVAFNKVKSLDA--EIQQHKKKNVPREMEKIQEANDKLMEKQKQ----IMTDRQVLTKK 897
+ ++K L+ E +K+ + + + ++E N++L Q Q TD TK
Sbjct: 392 ADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASA-TKS 450
Query: 898 IDTLKDEIAK---QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKE 954
+ L EI +EV+ R +N LR Q N ++ +EL E+L ++ ++NE E
Sbjct: 451 YENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSEN--ERIEELQEQLEQKHR-KMNELE 507
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFR---EKMYELH 1008
+ +Q ++ E + +L+KSL+ ++ E S +++K EK+ E+H
Sbjct: 508 T---EQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVH 561
Score = 42.3 bits (95), Expect = 0.010
Identities = 60/313 (19%), Positives = 135/313 (43%), Gaps = 18/313 (5%)
Query: 614 EDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS-- 671
E+L++A+A + ++ + K + + +E KR + ++K L E E +
Sbjct: 359 EELKKANAARTQLETYKRQVQDLHVKLSSE----SKRADTLAFEMKRLEEKHEALLKEKE 414
Query: 672 -LIEPEQKMT-TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAK 728
LIE + T +++ D Q + TK +E + + V+ E+ + +
Sbjct: 415 RLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHEN 474
Query: 729 QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEES 787
++ Q+ + R++ Q++L ++K+ L ++ +KE + Q++++D+ +L+E
Sbjct: 475 KMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQ 534
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+ + + A + E+++ K E++ + I I ++E A
Sbjct: 535 GSKSEGE---SSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAA 591
Query: 848 FNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK---IDTLKDE 904
K +++ K + + I+ + KL +IM R+ L +K I+ L+ E
Sbjct: 592 LQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESE 651
Query: 905 --IAKQEVYKRDL 915
+AK Y+ L
Sbjct: 652 CKVAKFRDYEEKL 664
Score = 39.5 bits (88), Expect = 0.071
Identities = 78/425 (18%), Positives = 174/425 (40%), Gaps = 41/425 (9%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ Q+E E A + Y +EL +++ + Q + +L + EE K++ +
Sbjct: 251 QLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDEL--TSLAEETRALKDEIDV 308
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+ K +E + + +N ++R +V LE E K
Sbjct: 309 LRATSDKANKLESTVEIYRQKLQ-DLN----DLRKQVKTLQETNMMYMHNTVSLEEELKK 363
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ + + + +D K TL+ +++L+++ L + + +
Sbjct: 364 ANAARTQLETYKRQVQDLHVKLSSESKRADTLA---FEMKRLEEKHEALLKEKERLIEQR 420
Query: 570 GQLKDNS---CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI 626
LK+ + C + N+++ +P + +V LQ + K +
Sbjct: 421 DTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHEN-KMLRL 479
Query: 627 LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQ-------IKTLNETVEEITMSLIEPEQKM 679
S NE+I L++ ++ Q +++ +++T+ I+ L + +E++ SL E K
Sbjct: 480 QQEGSENERIEELQE-QLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKS 538
Query: 680 ---TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM----TLDVATAKQVD- 731
+++K +++ + + + KK E +++ D++ + L+ A K+ +
Sbjct: 539 EGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDED 598
Query: 732 -------FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDI 781
+K + RN +KT KLN + ++ L K+ KE E+L ++ KV
Sbjct: 599 MKAMEERYKMYLEKARNVIKTLDPKLNPASAEIM-LLRKQLAEKERRIEILESECKVAKF 657
Query: 782 VNLEE 786
+ EE
Sbjct: 658 RDYEE 662
Score = 36.3 bits (80), Expect = 0.66
Identities = 26/83 (31%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
+ENE IEE Q+++ + + + + E E ++I +LQ+Q L +K + E+ K++ +
Sbjct: 484 SENE-RIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDL-QKSLQEQGSKSEGE 541
Query: 447 QLIVLKNKHKTALMELLGNVPEK 469
LK K + A ME L V E+
Sbjct: 542 SSSKLKQKLE-AHMEKLTEVHEE 563
Score = 33.9 bits (74), Expect = 3.5
Identities = 46/253 (18%), Positives = 108/253 (42%), Gaps = 14/253 (5%)
Query: 86 IVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEE 145
++ K++ +E ++K T + ++ Q L+ D S TK + A++ + + E
Sbjct: 409 LLKEKERLIEQRDTLKETNEELRCSQVQ--QDHLNQTDASA-TKSYENLAAEIMPVEYRE 465
Query: 146 LGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNL 205
+ + N ++ QE S E ++++E +++ + + L+ +++ K+ + L
Sbjct: 466 VFIRLQHENKMLRLQQEGS-----ENERIEELQEQLEQKHRKMNELETEQRLSKERIREL 520
Query: 206 KL-LENYATTVKAK--QKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQE 262
+ +E+ +++ + + E E S K EK+ + + L+ +
Sbjct: 521 QQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQ 580
Query: 263 KIDKRNEQIVETAKIAEIENITEVQTN---EEAENATKTILEKVESLKSDHKVQKSQADE 319
+ K NE K E E + E+A N KT+ K+ ++ + + Q E
Sbjct: 581 NVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAE 640
Query: 320 EEKKAQGFVDECR 332
+E++ + EC+
Sbjct: 641 KERRIEILESECK 653
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 56.0 bits (129), Expect = 8e-07
Identities = 92/525 (17%), Positives = 213/525 (40%), Gaps = 38/525 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
+N++ I++ Q+ + + +K +E E E +L ++ + + L E I EN ++
Sbjct: 429 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTE-ISENSSDLSQK 487
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAV----TINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L ++K++ A+ E+L + + +++ + V
Sbjct: 488 LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALE 547
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL----Q 559
E+ER +E + E +L + E + Y+ S Y + +E + E+ L Q
Sbjct: 548 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQ 605
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT----ED 615
+ I K K LK + E+ E ++ +L K ED
Sbjct: 606 EAQEEIMKLKDTLKSQMTQEASDEA-EDMKEAMNRMIDELNKQVSELSQLYKEAQAELED 664
Query: 616 LQRASAKKDEILSM--KSLNEKITTLKD----------TEIPQLEKRIVDVDTQIKTLNE 663
++ + +D K+ +EK+ L + +E+ ++++ TQ+K L +
Sbjct: 665 YRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVD 724
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
+E ++S+ E Q +TT + +M ++E +K+ E K + ++ + +
Sbjct: 725 AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKE-HLASKEVEVAKLEKQLLEEKAAMT 783
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
A + +++ S+L + V KL K+ + ++ + + + E+ +++ ++I
Sbjct: 784 DAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQT 843
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
L +SK+Q ++ +K E+ +++ I S + K
Sbjct: 844 LLKSKEQEVNELLQKFQQAQEEL-------AEMKRYAESSSKLEEDKDKKINEMSKEVTK 896
Query: 844 VEVAFNKVKSLDAEIQQHKKKNVPRE--MEKIQEANDKLMEKQKQ 886
++ A N + L K+++ E +++++ ++L E +KQ
Sbjct: 897 LKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQ 941
Score = 53.6 bits (123), Expect = 4e-06
Identities = 90/470 (19%), Positives = 209/470 (44%), Gaps = 55/470 (11%)
Query: 608 KLEKVTEDLQR----ASAKKDEI-LSMKSLNEKITTLKDTEIPQ----LEKRIVDVDTQ- 657
+L+++ +DLQ+ + A++ ++ + ++S ++ L +TEI + L +++ + ++
Sbjct: 436 QLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKY 495
Query: 658 ---IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI----QEIKTVTKKFEAVK 710
+K + +++ + L+ PE M H ++ + + I Q+++ ++ E K
Sbjct: 496 EEAMKEVLSVQKQMKLGLVSPES-MDNYSHFH-ELRVTEEEINVLKQDLQNALEESERNK 553
Query: 711 EQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
E+ +++ ++ V K K + + + NK+ L+EK +A+EE
Sbjct: 554 EKVRELEEKL---VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEE 610
Query: 771 LLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
++ + ++ + +E+ + + ++ L KE +A+ E R+
Sbjct: 611 IMKLKDTLKSQMT-QEASDEAEDMKEAMNRMIDELNKQVSELSQLYKE-AQAELEDYRKR 668
Query: 831 RDLIEAGSAYIAKVE-------VAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+ L + + YI K E ++ K+ DA + + V E+ ++++ D E
Sbjct: 669 KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKE 728
Query: 883 KQKQIMTDRQVLT----------KKIDTLKDEIAKQEVYKRDLDDNLCLRK-AQTDI--- 928
I QV+T +KI LK+ +A +EV L+ L K A TD
Sbjct: 729 NSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVP 788
Query: 929 -TNWQKQDDELNEKLNGIN---KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
++++K L +++ + KE + EKE + +++ Q ++E + E K++++
Sbjct: 789 RSSYEKLQSSLESEVSVLASKLKESVKEKEKV---HSEVVQIRSEVSQVKRE-KENIQTL 844
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
E+ ++ ++ +KF++ EL K + + DK + E +E
Sbjct: 845 LKSKEQEVN-ELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 893
Score = 33.9 bits (74), Expect = 3.5
Identities = 18/76 (23%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 385 KQAENELNIEECQ-QEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
+ AE+ +EE + ++INE K V + ++ ++ LSQ + ++ E +++ +K
Sbjct: 871 RYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQ 930
Query: 444 KEKQLIVLKNKHKTAL 459
+ QL K +H+ +
Sbjct: 931 LQNQLAECKKQHQEVI 946
Score = 33.5 bits (73), Expect = 4.7
Identities = 42/202 (20%), Positives = 90/202 (44%), Gaps = 9/202 (4%)
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKI 898
++ ++ V ++ L ++Q +++ R EK++E +KL+E++K + V ++
Sbjct: 523 SHFHELRVTEEEINVLKQDLQNALEES-ERNKEKVRELEEKLVEREKGTVIKPPV--EEY 579
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE-KESLI 957
+ +K + + + K Q K D L ++ +E + KE++
Sbjct: 580 EEMKSSYC-SVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMN 638
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGF--RNELEKSLSKDIEKKFREKMYEL-HVTKAID 1014
+L +Q +E + E + L+ + R LE ++ I K EK+ +L +V++A
Sbjct: 639 RMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKA 698
Query: 1015 KD-IREYAVALDKCLMEFHREK 1035
+D + E K L E + K
Sbjct: 699 EDALSEMKSQYSKVLNELTQLK 720
>AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosophila)
protein.
Length = 728
Score = 56.0 bits (129), Expect = 8e-07
Identities = 93/417 (22%), Positives = 192/417 (46%), Gaps = 50/417 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILS-MKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+L++ E+LQ A A+K+E+ + L+ ++TTL+D EK + + ++ +NE ++
Sbjct: 179 QLKRALEELQEALAEKEELRQRCEELDMQVTTLQD------EKNSLVSENEM--MNEKLD 230
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++ S +P + K H + +++++ + EA K+ D + +
Sbjct: 231 QLDGSFDDP-NTVVAKKYFHAQL-----QLEQLQEENFRLEAAKD-----DYRVHCEELE 279
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
+ ++F+ + L + + T + L L+ +K K + + ++K+QD+ +L +
Sbjct: 280 KQLIEFQHRNDELTSLAEET-RALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRK 338
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGSAYIAK 843
K LQ LE LK+ A+T++ R+ +DL S+ +
Sbjct: 339 QVKTLQE-------TNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKR 391
Query: 844 VEVAFNKVKSLDA--EIQQHKKKNVPREMEKIQEANDKLMEKQKQ----IMTDRQVLTKK 897
+ ++K L+ E +K+ + + + ++E N++L Q Q TD TK
Sbjct: 392 ADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASA-TKS 450
Query: 898 IDTLKDEIAK---QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKE 954
+ L EI +EV+ R +N LR Q N ++ +EL E+L ++ ++NE E
Sbjct: 451 YENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSEN--ERIEELQEQLEQKHR-KMNELE 507
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFR---EKMYELH 1008
+ +Q ++ E + +L+KSL+ ++ E S +++K EK+ E+H
Sbjct: 508 T---EQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVH 561
Score = 42.3 bits (95), Expect = 0.010
Identities = 60/313 (19%), Positives = 135/313 (43%), Gaps = 18/313 (5%)
Query: 614 EDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS-- 671
E+L++A+A + ++ + K + + +E KR + ++K L E E +
Sbjct: 359 EELKKANAARTQLETYKRQVQDLHVKLSSE----SKRADTLAFEMKRLEEKHEALLKEKE 414
Query: 672 -LIEPEQKMT-TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAK 728
LIE + T +++ D Q + TK +E + + V+ E+ + +
Sbjct: 415 RLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHEN 474
Query: 729 QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEES 787
++ Q+ + R++ Q++L ++K+ L ++ +KE + Q++++D+ +L+E
Sbjct: 475 KMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQ 534
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+ + + A + E+++ K E++ + I I ++E A
Sbjct: 535 GSKSEGE---SSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAA 591
Query: 848 FNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK---IDTLKDE 904
K +++ K + + I+ + KL +IM R+ L +K I+ L+ E
Sbjct: 592 LQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESE 651
Query: 905 --IAKQEVYKRDL 915
+AK Y+ L
Sbjct: 652 CKVAKFRDYEEKL 664
Score = 39.5 bits (88), Expect = 0.071
Identities = 78/425 (18%), Positives = 174/425 (40%), Gaps = 41/425 (9%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ Q+E E A + Y +EL +++ + Q + +L + EE K++ +
Sbjct: 251 QLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDEL--TSLAEETRALKDEIDV 308
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+ K +E + + +N ++R +V LE E K
Sbjct: 309 LRATSDKANKLESTVEIYRQKLQ-DLN----DLRKQVKTLQETNMMYMHNTVSLEEELKK 363
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ + + + +D K TL+ +++L+++ L + + +
Sbjct: 364 ANAARTQLETYKRQVQDLHVKLSSESKRADTLA---FEMKRLEEKHEALLKEKERLIEQR 420
Query: 570 GQLKDNS---CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI 626
LK+ + C + N+++ +P + +V LQ + K +
Sbjct: 421 DTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHEN-KMLRL 479
Query: 627 LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQ-------IKTLNETVEEITMSLIEPEQKM 679
S NE+I L++ ++ Q +++ +++T+ I+ L + +E++ SL E K
Sbjct: 480 QQEGSENERIEELQE-QLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKS 538
Query: 680 ---TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM----TLDVATAKQVD- 731
+++K +++ + + + KK E +++ D++ + L+ A K+ +
Sbjct: 539 EGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDED 598
Query: 732 -------FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDI 781
+K + RN +KT KLN + ++ L K+ KE E+L ++ KV
Sbjct: 599 MKAMEERYKMYLEKARNVIKTLDPKLNPASAEIM-LLRKQLAEKERRIEILESECKVAKF 657
Query: 782 VNLEE 786
+ EE
Sbjct: 658 RDYEE 662
Score = 36.3 bits (80), Expect = 0.66
Identities = 26/83 (31%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
+ENE IEE Q+++ + + + + E E ++I +LQ+Q L +K + E+ K++ +
Sbjct: 484 SENE-RIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDL-QKSLQEQGSKSEGE 541
Query: 447 QLIVLKNKHKTALMELLGNVPEK 469
LK K + A ME L V E+
Sbjct: 542 SSSKLKQKLE-AHMEKLTEVHEE 563
Score = 33.9 bits (74), Expect = 3.5
Identities = 46/253 (18%), Positives = 108/253 (42%), Gaps = 14/253 (5%)
Query: 86 IVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEE 145
++ K++ +E ++K T + ++ Q L+ D S TK + A++ + + E
Sbjct: 409 LLKEKERLIEQRDTLKETNEELRCSQVQ--QDHLNQTDASA-TKSYENLAAEIMPVEYRE 465
Query: 146 LGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNL 205
+ + N ++ QE S E ++++E +++ + + L+ +++ K+ + L
Sbjct: 466 VFIRLQHENKMLRLQQEGS-----ENERIEELQEQLEQKHRKMNELETEQRLSKERIREL 520
Query: 206 KL-LENYATTVKAK--QKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQE 262
+ +E+ +++ + + E E S K EK+ + + L+ +
Sbjct: 521 QQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQ 580
Query: 263 KIDKRNEQIVETAKIAEIENITEVQTN---EEAENATKTILEKVESLKSDHKVQKSQADE 319
+ K NE K E E + E+A N KT+ K+ ++ + + Q E
Sbjct: 581 NVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAE 640
Query: 320 EEKKAQGFVDECR 332
+E++ + EC+
Sbjct: 641 KERRIEILESECK 653
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 56.0 bits (129), Expect = 8e-07
Identities = 92/525 (17%), Positives = 213/525 (40%), Gaps = 38/525 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
+N++ I++ Q+ + + +K +E E E +L ++ + + L E I EN ++
Sbjct: 426 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTE-ISENSSDLSQK 484
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAV----TINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L ++K++ A+ E+L + + +++ + V
Sbjct: 485 LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALE 544
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL----Q 559
E+ER +E + E +L + E + Y+ S Y + +E + E+ L Q
Sbjct: 545 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQ 602
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT----ED 615
+ I K K LK + E+ E ++ +L K ED
Sbjct: 603 EAQEEIMKLKDTLKSQMTQEASDEA-EDMKEAMNRMIDELNKQVSELSQLYKEAQAELED 661
Query: 616 LQRASAKKDEILSM--KSLNEKITTLKD----------TEIPQLEKRIVDVDTQIKTLNE 663
++ + +D K+ +EK+ L + +E+ ++++ TQ+K L +
Sbjct: 662 YRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVD 721
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
+E ++S+ E Q +TT + +M ++E +K+ E K + ++ + +
Sbjct: 722 AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKE-HLASKEVEVAKLEKQLLEEKAAMT 780
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
A + +++ S+L + V KL K+ + ++ + + + E+ +++ ++I
Sbjct: 781 DAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQT 840
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAK 843
L +SK+Q ++ +K E+ +++ I S + K
Sbjct: 841 LLKSKEQEVNELLQKFQQAQEEL-------AEMKRYAESSSKLEEDKDKKINEMSKEVTK 893
Query: 844 VEVAFNKVKSLDAEIQQHKKKNVPRE--MEKIQEANDKLMEKQKQ 886
++ A N + L K+++ E +++++ ++L E +KQ
Sbjct: 894 LKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQ 938
Score = 53.6 bits (123), Expect = 4e-06
Identities = 90/470 (19%), Positives = 209/470 (44%), Gaps = 55/470 (11%)
Query: 608 KLEKVTEDLQR----ASAKKDEI-LSMKSLNEKITTLKDTEIPQ----LEKRIVDVDTQ- 657
+L+++ +DLQ+ + A++ ++ + ++S ++ L +TEI + L +++ + ++
Sbjct: 433 QLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKY 492
Query: 658 ---IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI----QEIKTVTKKFEAVK 710
+K + +++ + L+ PE M H ++ + + I Q+++ ++ E K
Sbjct: 493 EEAMKEVLSVQKQMKLGLVSPES-MDNYSHFH-ELRVTEEEINVLKQDLQNALEESERNK 550
Query: 711 EQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
E+ +++ ++ V K K + + + NK+ L+EK +A+EE
Sbjct: 551 EKVRELEEKL---VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEE 607
Query: 771 LLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
++ + ++ + +E+ + + ++ L KE +A+ E R+
Sbjct: 608 IMKLKDTLKSQMT-QEASDEAEDMKEAMNRMIDELNKQVSELSQLYKE-AQAELEDYRKR 665
Query: 831 RDLIEAGSAYIAKVE-------VAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+ L + + YI K E ++ K+ DA + + V E+ ++++ D E
Sbjct: 666 KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKE 725
Query: 883 KQKQIMTDRQVLT----------KKIDTLKDEIAKQEVYKRDLDDNLCLRK-AQTDI--- 928
I QV+T +KI LK+ +A +EV L+ L K A TD
Sbjct: 726 NSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVP 785
Query: 929 -TNWQKQDDELNEKLNGIN---KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
++++K L +++ + KE + EKE + +++ Q ++E + E K++++
Sbjct: 786 RSSYEKLQSSLESEVSVLASKLKESVKEKEKV---HSEVVQIRSEVSQVKRE-KENIQTL 841
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
E+ ++ ++ +KF++ EL K + + DK + E +E
Sbjct: 842 LKSKEQEVN-ELLQKFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKE 890
Score = 33.9 bits (74), Expect = 3.5
Identities = 18/76 (23%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 385 KQAENELNIEECQ-QEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
+ AE+ +EE + ++INE K V + ++ ++ LSQ + ++ E +++ +K
Sbjct: 868 RYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQ 927
Query: 444 KEKQLIVLKNKHKTAL 459
+ QL K +H+ +
Sbjct: 928 LQNQLAECKKQHQEVI 943
Score = 33.5 bits (73), Expect = 4.7
Identities = 42/202 (20%), Positives = 90/202 (44%), Gaps = 9/202 (4%)
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKI 898
++ ++ V ++ L ++Q +++ R EK++E +KL+E++K + V ++
Sbjct: 520 SHFHELRVTEEEINVLKQDLQNALEES-ERNKEKVRELEEKLVEREKGTVIKPPV--EEY 576
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE-KESLI 957
+ +K + + + K Q K D L ++ +E + KE++
Sbjct: 577 EEMKSSYC-SVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMN 635
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGF--RNELEKSLSKDIEKKFREKMYEL-HVTKAID 1014
+L +Q +E + E + L+ + R LE ++ I K EK+ +L +V++A
Sbjct: 636 RMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKA 695
Query: 1015 KD-IREYAVALDKCLMEFHREK 1035
+D + E K L E + K
Sbjct: 696 EDALSEMKSQYSKVLNELTQLK 717
>AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein.
Length = 728
Score = 56.0 bits (129), Expect = 8e-07
Identities = 93/417 (22%), Positives = 192/417 (46%), Gaps = 50/417 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILS-MKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+L++ E+LQ A A+K+E+ + L+ ++TTL+D EK + + ++ +NE ++
Sbjct: 179 QLKRALEELQEALAEKEELRQRCEELDMQVTTLQD------EKNSLVSENEM--MNEKLD 230
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++ S +P + K H + +++++ + EA K+ D + +
Sbjct: 231 QLDGSFDDP-NTVVAKKYFHAQL-----QLEQLQEENFRLEAAKD-----DYRVHCEELE 279
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
+ ++F+ + L + + T + L L+ +K K + + ++K+QD+ +L +
Sbjct: 280 KQLIEFQHRNDELTSLAEET-RALKDEIDVLRATSDKANKLESTVEIYRQKLQDLNDLRK 338
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV---VRRNRDLIEAGSAYIAK 843
K LQ LE LK+ A+T++ R+ +DL S+ +
Sbjct: 339 QVKTLQE-------TNMMYMHNTVSLEEELKKANAARTQLETYKRQVQDLHVKLSSESKR 391
Query: 844 VEVAFNKVKSLDA--EIQQHKKKNVPREMEKIQEANDKLMEKQKQ----IMTDRQVLTKK 897
+ ++K L+ E +K+ + + + ++E N++L Q Q TD TK
Sbjct: 392 ADTLAFEMKRLEEKHEALLKEKERLIEQRDTLKETNEELRCSQVQQDHLNQTDASA-TKS 450
Query: 898 IDTLKDEIAK---QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKE 954
+ L EI +EV+ R +N LR Q N ++ +EL E+L ++ ++NE E
Sbjct: 451 YENLAAEIMPVEYREVFIRLQHENKMLRLQQEGSEN--ERIEELQEQLEQKHR-KMNELE 507
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFR---EKMYELH 1008
+ +Q ++ E + +L+KSL+ ++ E S +++K EK+ E+H
Sbjct: 508 T---EQRLSKERIRELQQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVH 561
Score = 42.3 bits (95), Expect = 0.010
Identities = 60/313 (19%), Positives = 135/313 (43%), Gaps = 18/313 (5%)
Query: 614 EDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS-- 671
E+L++A+A + ++ + K + + +E KR + ++K L E E +
Sbjct: 359 EELKKANAARTQLETYKRQVQDLHVKLSSE----SKRADTLAFEMKRLEEKHEALLKEKE 414
Query: 672 -LIEPEQKMT-TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVD-SEMTLDVATAK 728
LIE + T +++ D Q + TK +E + + V+ E+ + +
Sbjct: 415 RLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHEN 474
Query: 729 QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI-VNLEES 787
++ Q+ + R++ Q++L ++K+ L ++ +KE + Q++++D+ +L+E
Sbjct: 475 KMLRLQQEGSENERIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQ 534
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+ + + A + E+++ K E++ + I I ++E A
Sbjct: 535 GSKSEGE---SSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAA 591
Query: 848 FNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKK---IDTLKDE 904
K +++ K + + I+ + KL +IM R+ L +K I+ L+ E
Sbjct: 592 LQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKERRIEILESE 651
Query: 905 --IAKQEVYKRDL 915
+AK Y+ L
Sbjct: 652 CKVAKFRDYEEKL 664
Score = 39.5 bits (88), Expect = 0.071
Identities = 78/425 (18%), Positives = 174/425 (40%), Gaps = 41/425 (9%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLI 449
+L +E+ Q+E E A + Y +EL +++ + Q + +L + EE K++ +
Sbjct: 251 QLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDEL--TSLAEETRALKDEIDV 308
Query: 450 VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH 509
+ K +E + + +N ++R +V LE E K
Sbjct: 309 LRATSDKANKLESTVEIYRQKLQ-DLN----DLRKQVKTLQETNMMYMHNTVSLEEELKK 363
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
+ + + + +D K TL+ +++L+++ L + + +
Sbjct: 364 ANAARTQLETYKRQVQDLHVKLSSESKRADTLA---FEMKRLEEKHEALLKEKERLIEQR 420
Query: 570 GQLKDNS---CCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEI 626
LK+ + C + N+++ +P + +V LQ + K +
Sbjct: 421 DTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQHEN-KMLRL 479
Query: 627 LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQ-------IKTLNETVEEITMSLIEPEQKM 679
S NE+I L++ ++ Q +++ +++T+ I+ L + +E++ SL E K
Sbjct: 480 QQEGSENERIEELQE-QLEQKHRKMNELETEQRLSKERIRELQQQIEDLQKSLQEQGSKS 538
Query: 680 ---TTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM----TLDVATAKQVD- 731
+++K +++ + + + KK E +++ D++ + L+ A K+ +
Sbjct: 539 EGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQKINELEAALQKKDED 598
Query: 732 -------FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDI 781
+K + RN +KT KLN + ++ L K+ KE E+L ++ KV
Sbjct: 599 MKAMEERYKMYLEKARNVIKTLDPKLNPASAEIM-LLRKQLAEKERRIEILESECKVAKF 657
Query: 782 VNLEE 786
+ EE
Sbjct: 658 RDYEE 662
Score = 36.3 bits (80), Expect = 0.66
Identities = 26/83 (31%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
+ENE IEE Q+++ + + + + E E ++I +LQ+Q L +K + E+ K++ +
Sbjct: 484 SENE-RIEELQEQLEQKHRKMNELETEQRLSKERIRELQQQIEDL-QKSLQEQGSKSEGE 541
Query: 447 QLIVLKNKHKTALMELLGNVPEK 469
LK K + A ME L V E+
Sbjct: 542 SSSKLKQKLE-AHMEKLTEVHEE 563
Score = 33.9 bits (74), Expect = 3.5
Identities = 46/253 (18%), Positives = 108/253 (42%), Gaps = 14/253 (5%)
Query: 86 IVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEE 145
++ K++ +E ++K T + ++ Q L+ D S TK + A++ + + E
Sbjct: 409 LLKEKERLIEQRDTLKETNEELRCSQVQ--QDHLNQTDASA-TKSYENLAAEIMPVEYRE 465
Query: 146 LGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNL 205
+ + N ++ QE S E ++++E +++ + + L+ +++ K+ + L
Sbjct: 466 VFIRLQHENKMLRLQQEGS-----ENERIEELQEQLEQKHRKMNELETEQRLSKERIREL 520
Query: 206 KL-LENYATTVKAK--QKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQE 262
+ +E+ +++ + + E E S K EK+ + + L+ +
Sbjct: 521 QQQIEDLQKSLQEQGSKSEGESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQ 580
Query: 263 KIDKRNEQIVETAKIAEIENITEVQTN---EEAENATKTILEKVESLKSDHKVQKSQADE 319
+ K NE K E E + E+A N KT+ K+ ++ + + Q E
Sbjct: 581 NVQKINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAE 640
Query: 320 EEKKAQGFVDECR 332
+E++ + EC+
Sbjct: 641 KERRIEILESECK 653
>AB046785-1|BAB13391.2| 1313|Homo sapiens KIAA1565 protein protein.
Length = 1313
Score = 56.0 bits (129), Expect = 8e-07
Identities = 103/565 (18%), Positives = 224/565 (39%), Gaps = 22/565 (3%)
Query: 388 ENELNIEECQQEINE-DEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKE- 445
E ++ ++ Q+ + + E E+++ +L +I +LQ Q A LKE E + +E
Sbjct: 680 ETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEAHH-EATCRHEEE 738
Query: 446 -KQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLE 504
KQL V + KT L E L E + + + + E +
Sbjct: 739 KKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQ 798
Query: 505 AERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFI 564
+ +E L + T ++++ K + + L + EKLQ E ++L++ +
Sbjct: 799 ELEQFHQEQLTSLVEKHTLEKEELRKEL-LEKHQRELQEGRYESEKLQQENSILRNEITT 857
Query: 565 INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD 624
+N+ + + + L G + E + + L+K +L+ + + D
Sbjct: 858 LNE-EDSISNLKLGTL--NGSQEEMQKTETVKQENAAVQKMVENLKKQISELKIKNQQLD 914
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDV--DTQIKTLNETVEEITMSLIEPEQKMTTA 682
L L++K + ++ +L +R+ ++ + + N +EE ++++
Sbjct: 915 --LENTELSQK-NSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERC 971
Query: 683 K-QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRN 741
K Q + L+ + E+K T + D +M DF+QKIS++ +
Sbjct: 972 KVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLS 1031
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAK--EELLNTQKKVQDIVNLEESKKQLQSDCXXXX 799
+ K+ A +++L + +K K+ E + T K+ Q + E L+S
Sbjct: 1032 YNEKLLKEKEALSEELNSCVDKLAKSSLLEHRIATMKQEQK--SWEHQSASLKSQLVASQ 1089
Query: 800 XXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQ 859
+ + + + ++++ V ++ ++ ++ + K ++ KS EI
Sbjct: 1090 EKVQNLEDTVQNVNLQM-SRMKSDLRVTQQEKEALKQEVMSLHK-QLQNAGGKSWAPEIA 1147
Query: 860 QHKKKNVPREMEKIQEANDKLMEKQKQIM-TDRQVLTKKIDTLKDEIAKQEVYKRDLDDN 918
H ++ + D LM +++Q++ + + L + K E+ R L+ N
Sbjct: 1148 THPSGLHNQQKRLSWDKLDHLMNEEQQLLWQENERLQTMVQNTKAELTHSREKVRQLESN 1207
Query: 919 LCLRKAQTDITNWQKQDDELNEKLN 943
L L K Q + + EKL+
Sbjct: 1208 L-LPKHQKHLNPSGTMNPTEQEKLS 1231
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 56.0 bits (129), Expect = 8e-07
Identities = 93/526 (17%), Positives = 216/526 (41%), Gaps = 40/526 (7%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
+N++ I++ Q+ + + +K +E E E +L ++ + + L E I EN ++
Sbjct: 435 DNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTE-ISENSSDLSQK 493
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAV----TINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
L ++K++ A+ E+L + + +++ + V
Sbjct: 494 LKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQNALE 553
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVL----Q 559
E+ER +E + E +L + E + Y+ S Y + +E + E+ L Q
Sbjct: 554 ESERN--KEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQ 611
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVT----ED 615
+ I K K LK + E+ E ++ +L K ED
Sbjct: 612 EAQEEIMKLKDTLKSQMTQEASDEA-EDMKEAMNRMIDELNKQVSELSQLYKEAQAELED 670
Query: 616 LQRASAKKDEILSM--KSLNEKITTLKD----------TEIPQLEKRIVDVDTQIKTLNE 663
++ + +D K+ +EK+ L + +E+ ++++ TQ+K L +
Sbjct: 671 YRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVD 730
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
+E ++S+ E Q +TT + +M ++E +K+ E K + ++ + +
Sbjct: 731 AQKENSVSITEHLQVITTLRTAAKEMEEKISNLKE-HLASKEVEVAKLEKQLLEEKAAMT 789
Query: 724 VATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
A + +++ S+L + V KL K+ + ++ + + + E+ +++ ++I
Sbjct: 790 DAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQT 849
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD-LIEAGSAYIA 842
L +SK+Q ++ E+A ++ + + ++D I S +
Sbjct: 850 LLKSKEQEVNELLQKFQQAQE--------ELAEMKRYSESSSKLEEDKDKKINEMSKEVT 901
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPRE--MEKIQEANDKLMEKQKQ 886
K++ A N + L K+++ E +++++ ++L E +KQ
Sbjct: 902 KLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQ 947
Score = 54.4 bits (125), Expect = 2e-06
Identities = 90/470 (19%), Positives = 209/470 (44%), Gaps = 55/470 (11%)
Query: 608 KLEKVTEDLQR----ASAKKDEI-LSMKSLNEKITTLKDTEIPQ----LEKRIVDVDTQ- 657
+L+++ +DLQ+ + A++ ++ + ++S ++ L +TEI + L +++ + ++
Sbjct: 442 QLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKY 501
Query: 658 ---IKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI----QEIKTVTKKFEAVK 710
+K + +++ + L+ PE M H ++ + + I Q+++ ++ E K
Sbjct: 502 EEAMKEVLSVQKQMKLGLVSPES-MDNYSHFH-ELRVTEEEINVLKQDLQNALEESERNK 559
Query: 711 EQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
E+ +++ ++ V K K + + + NK+ L+EK +A+EE
Sbjct: 560 EKVRELEEKL---VEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEE 616
Query: 771 LLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
++ + ++ + +E+ + + ++ L KE +A+ E R+
Sbjct: 617 IMKLKDTLKSQMT-QEASDEAEDMKEAMNRMIDELNKQVSELSQLYKE-AQAELEDYRKR 674
Query: 831 RDLIEAGSAYIAKVE-------VAFNKVKSLDAEIQQHKK-KNVPREMEKIQEANDKLME 882
+ L + + YI K E ++ K+ DA + + V E+ ++++ D E
Sbjct: 675 KSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKE 734
Query: 883 KQKQIMTDRQVLT----------KKIDTLKDEIAKQEVYKRDLDDNLCLRK-AQTDI--- 928
I QV+T +KI LK+ +A +EV L+ L K A TD
Sbjct: 735 NSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAAMTDAMVP 794
Query: 929 -TNWQKQDDELNEKLNGIN---KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGF 984
++++K L +++ + KE + EKE + +++ Q ++E + E K++++
Sbjct: 795 RSSYEKLQSSLESEVSVLASKLKESVKEKEKV---HSEVVQIRSEVSQVKRE-KENIQTL 850
Query: 985 RNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
E+ ++ ++ +KF++ EL K + + DK + E +E
Sbjct: 851 LKSKEQEVN-ELLQKFQQAQEELAEMKRYSESSSKLEEDKDKKINEMSKE 899
Score = 33.5 bits (73), Expect = 4.7
Identities = 42/202 (20%), Positives = 90/202 (44%), Gaps = 9/202 (4%)
Query: 839 AYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKI 898
++ ++ V ++ L ++Q +++ R EK++E +KL+E++K + V ++
Sbjct: 529 SHFHELRVTEEEINVLKQDLQNALEES-ERNKEKVRELEEKLVEREKGTVIKPPV--EEY 585
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE-KESLI 957
+ +K + + + K Q K D L ++ +E + KE++
Sbjct: 586 EEMKSSYC-SVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMN 644
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGF--RNELEKSLSKDIEKKFREKMYEL-HVTKAID 1014
+L +Q +E + E + L+ + R LE ++ I K EK+ +L +V++A
Sbjct: 645 RMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKA 704
Query: 1015 KD-IREYAVALDKCLMEFHREK 1035
+D + E K L E + K
Sbjct: 705 EDALSEMKSQYSKVLNELTQLK 726
Score = 32.7 bits (71), Expect = 8.2
Identities = 17/76 (22%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Query: 385 KQAENELNIEECQ-QEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
+ +E+ +EE + ++INE K V + ++ ++ LSQ + ++ E +++ +K
Sbjct: 877 RYSESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQ 936
Query: 444 KEKQLIVLKNKHKTAL 459
+ QL K +H+ +
Sbjct: 937 LQNQLAECKKQHQEVI 952
>X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa protein.
Length = 976
Score = 55.6 bits (128), Expect = 1e-06
Identities = 103/451 (22%), Positives = 199/451 (44%), Gaps = 54/451 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+L+ +T +LQ+ S++ +E+ K+T K+ E+ +L+K + + +T + N+ E+
Sbjct: 404 QLKILTMELQKKSSELEEMT-------KLTNNKEVELEELKKVLGEKETLLYE-NKQFEK 455
Query: 668 ITMSLIEPEQKM-----TTAKQIHGDMPMLDR-------YIQEIKTVTKKFEAVKEQCGD 715
I L EQ++ K++H L Y +E+K + K E E+ +
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL--KTELENEKLKN 513
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
+ + + + + Q+ S + +K Q+ +N +NKK + E+ K E L T+
Sbjct: 514 TELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN-NNKKQE---ERMLKQIENLQETE 569
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
++++ LE +++L+ L ++ K + E+ + N+ L +
Sbjct: 570 TQLRN--ELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKK 627
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREME--KIQEAN-DKLMEKQKQ 886
G+A ++ V KV L+ E++ K+K +E+E KI E N + +EK K
Sbjct: 628 KGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKV 687
Query: 887 IMTDRQVLTKKID-----TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD----- 936
I + L K+ID + + +A E +K D + R ++ + ++Q+
Sbjct: 688 IADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRA 747
Query: 937 ELNEKLNGINKEELNEKESLII---KQTKLFQQKAECTGALSELK-KSLKGFRNELEKSL 992
L +L+ + E L+ K+ L I ++ KL ++ E T L E K K + F E +
Sbjct: 748 SLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIY 807
Query: 993 SKDIEKKFREKMYELHVTK---AIDKDIREY 1020
K K + + T I KD R+Y
Sbjct: 808 WKLDSKAVPSQTVSRNFTSVDHGISKDKRDY 838
Score = 39.9 bits (89), Expect = 0.054
Identities = 53/231 (22%), Positives = 106/231 (45%), Gaps = 20/231 (8%)
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK-SLDAEIQQH----KKKNVP 867
+V+ + ++ K ++ NR +IEA I +++ KV L+ IQ++ K+ N
Sbjct: 120 KVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNAT 179
Query: 868 REM-EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
R + ++E + EK K+ +R+ + L + I K +L + ++
Sbjct: 180 RHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAHGEL--RVQAENSRL 237
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKES----LIIKQTKLFQQKAECTGALSELKKSLK 982
++ K+D E + L K+E+N+KE L+I+ T+ + + T L E + +
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV- 296
Query: 983 GFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR---EYAVALDKCLME 1030
N+LE+ E + + H+TK ++ DI+ + +V+ K L E
Sbjct: 297 ---NQLEEKTKLQSENLKQSIEKQHHLTKELE-DIKVSLQRSVSTQKALEE 343
Score = 39.9 bits (89), Expect = 0.054
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 211 YATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQ 270
Y+ VK + ELE+ KNT K++ E E + + LE +NQ++ D N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD-MTLELKNQQE-DINNNK 552
Query: 271 IVETAKIAEIENI--TEVQTNEEAENATKTILEKVESLKSDHKVQKSQ 316
E + +IEN+ TE Q E E + + +K + +K K+ KS+
Sbjct: 553 KQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKC--KLDKSE 598
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 55.6 bits (128), Expect = 1e-06
Identities = 105/610 (17%), Positives = 245/610 (40%), Gaps = 62/610 (10%)
Query: 385 KQAENEL--NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLK 442
+Q + EL + + E EK +++ EQEM+E+ +K+ K AK K+++++E
Sbjct: 1640 RQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF----AKSKQQKILE---- 1691
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
+ +N A + G+ K+ T+ ++ E+
Sbjct: 1692 ------LEEENDRLRAEVHPAGDT-AKECMETLLSSNASMKEELERVKMEYETLSKKFQS 1744
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSM 562
L +E+ + E + + + ++ ED + K + EK ++ NV +
Sbjct: 1745 LMSEKDSLSEEVQDLKHQI---EDNVSKQANLE-----------ATEKHDNQTNVTEEGT 1790
Query: 563 FII--NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS 620
I + S P C+ + + L+++ + +R +
Sbjct: 1791 QSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIA 1850
Query: 621 AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITM--SLIEPEQK 678
++E K ++ + K+T + Q+ + D ++K L E V ++ + I+ E
Sbjct: 1851 GLEEEKQKNKEFSQTLENEKNTLLSQISTK----DGELKMLQEEVTKMNLLNQQIQEELS 1906
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDV-DSEMTLDVATAKQVDFKQKIS 737
T + + D + + + + ++ C DV D+++ ++ ++ + K+ +S
Sbjct: 1907 RVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVS 1966
Query: 738 TLRNRVKTTQKKLNAHNKKLQTLY-EKKTKAKEELLNTQ--KKVQDIVNLEESK-KQLQS 793
L + K+ +++ Y EK A++E N K++Q+++ ++ + KQLQ
Sbjct: 1967 ELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2026
Query: 794 DCXXXXXXXXXXXXAITPLEVALKEK---IEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK 850
DC + LE E +E E + + + + A +A +V +
Sbjct: 2027 DCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDD 2086
Query: 851 VKS-----------LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKID 899
+S L E+Q +K+ + +K ++ +L + +++ + +++ + +K+D
Sbjct: 2087 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLD 2146
Query: 900 TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--EELNEKESLI 957
L+ E K + + + + L K ++ Q+ D +L K L + +
Sbjct: 2147 ALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRV 2204
Query: 958 IKQTKLFQQK 967
I + K +++K
Sbjct: 2205 IDEAKKWERK 2214
Score = 54.8 bits (126), Expect = 2e-06
Identities = 97/433 (22%), Positives = 192/433 (44%), Gaps = 45/433 (10%)
Query: 611 KVTEDLQRASAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
++ L+ A+K E+ L + S ++T K E+ QL+++I +I++L E
Sbjct: 1306 QIKAQLKEIEAEKVELELKVSSTTSELTK-KSEEVFQLQEQINKQGLEIESLKTVSHEAE 1364
Query: 670 MSLIEPEQKMTTAK-QIHG--DMPMLDRYIQEI-KTVTKKFEAVKEQCGDV-DSEMTLDV 724
+ +QK+ +++ QI G + L + E+ K ++KK E V G + + E L
Sbjct: 1365 VHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTK 1424
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ ++ + I L +++ K+ + K+LQ EL ++K ++I
Sbjct: 1425 IQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQV----------ELCEMKQKPEEIGEE 1474
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
+K+Q+Q A+ + ALKE ++ E + R IE + +A V
Sbjct: 1475 SRAKQQIQ----------RKLQAALISRKEALKEN-KSLQEELSLARGTIERLTKSLADV 1523
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
E ++V + Q +K V + +QE DKL+ + + + + Q L+ ++LK
Sbjct: 1524 E---SQVSA-----QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLA 1575
Query: 905 IAKQEVYKRDLDDNLCLRKAQ--TDITNWQKQDDELNEKLNGI--NKEEL-NEKESLIIK 959
+ K L + K+ + T WQ++ EL ++ + + E + NE E +
Sbjct: 1576 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHV 1635
Query: 960 QTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
+ Q+K E G L + + K +L+++ +++E + +EKM + K+ + I E
Sbjct: 1636 VEAVRQEKQELYGKLRSTEANKKETEKQLQEA-EQEME-EMKEKMRKF--AKSKQQKILE 1691
Query: 1020 YAVALDKCLMEFH 1032
D+ E H
Sbjct: 1692 LEEENDRLRAEVH 1704
Score = 54.8 bits (126), Expect = 2e-06
Identities = 117/637 (18%), Positives = 252/637 (39%), Gaps = 60/637 (9%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQ-KQTAKLKEKEMIEENLK 442
H + EL ++E QQE+ + +K +Y++++ L + + L+ QT K+ E+ +ENL
Sbjct: 2006 HAKELQEL-LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLA 2064
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPEKDFAVTIN-----KFECEVRNEVXXXXXXXXXXX 497
+ K + + A ++L + + + A + K E + E
Sbjct: 2065 QAVEHR--KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDED 2122
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNV 557
+AE KH++E N + +K++ VTL+K V++LQ+ +
Sbjct: 2123 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2182
Query: 558 LQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQ 617
+ + K L+D+ +R + + + K E++
Sbjct: 2183 TVTQLAAFTKSMSSLQDDR-----DRVIDEAKKWERKFSDA------IQSKEEEIRLKED 2231
Query: 618 RASAKKDEI----LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLI 673
S KD++ + M+ L I+ L+ + K +V Q K + E L
Sbjct: 2232 NCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLS 2291
Query: 674 EPEQKMTTAKQIHGDMPMLDRYIQEIK----TVTKKFEAVKEQCGDVDS---EMTLDVAT 726
+ E+ ++ L+ ++ +K ++ E KEQ G+++ + D+
Sbjct: 2292 QLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQN 2351
Query: 727 AK--QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+K + + R +++N +K+ +L K +A + + ++ D +
Sbjct: 2352 SKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD-KEI 2410
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
+E + L + A+ ++ K E +++ L +++ +
Sbjct: 2411 KELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL----DSFVKSM 2466
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
N + + QQ +++++ +EK Q + E K + + + L +D L E
Sbjct: 2467 SSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNK-LKEEIRGLRSHMDDLNSE 2525
Query: 905 IAKQEV----YKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
AK + Y+ DL+ + ++ +Q QKQ + + +L + + L K
Sbjct: 2526 NAKLDAELIQYREDLNQVITIKDSQ------QKQ----------LLEVQLQQNKELENKY 2569
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE 997
KL ++ E A +L++S + E ++ LSK+IE
Sbjct: 2570 AKLEEKLKESEEANEDLRRSFNALQEE-KQDLSKEIE 2605
Score = 50.0 bits (114), Expect = 5e-05
Identities = 113/648 (17%), Positives = 258/648 (39%), Gaps = 46/648 (7%)
Query: 388 ENELNIEECQQEINEDEKAV------EQYEQEMDELSQKITKLQKQTAKLKEKEMIEENL 441
E E++ E QQ++ + + + + ++DEL + I+K ++ + L + +E
Sbjct: 1362 EAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAA 1421
Query: 442 KTK-EKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFE-CEVRNEVXXXXXXXXXXXXX 499
TK + ++I ++ K +L E D + + E CE++ +
Sbjct: 1422 LTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRAKQQI 1481
Query: 500 XXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQ 559
L+A +E+L E +S ++++ A GT L+K VE QN +
Sbjct: 1482 QRKLQAALISRKEALKENKS----LQEELSLARGTIE---RLTKSLADVESQVSAQNKEK 1534
Query: 560 SSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRA 619
++ + +D + EN+S K EK+ ++++
Sbjct: 1535 DTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDK-EKLVKEIE-- 1591
Query: 620 SAKKDEILSMKSLNEKITTL-KDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
S K +I EK L K+ EI L + +V + + + VE + E K
Sbjct: 1592 SLKSSKIAESTEWQEKHKELQKEYEI--LLQSYENVSNEAERIQHVVEAVRQEKQELYGK 1649
Query: 679 MTTA----KQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ----CGDVDSEMTLDVA----T 726
+ + K+ + ++ ++E+K +KF K+Q + + + +V T
Sbjct: 1650 LRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGDT 1709
Query: 727 AKQV--DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
AK+ ++++ ++ + + +KK Q+L +K EE+ + + +++D N+
Sbjct: 1710 AKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIED--NV 1767
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTE-VVRRNRDLIEAGSAYIAK 843
+ ++ P E ++ + T + ++ + ++K
Sbjct: 1768 SKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSK 1827
Query: 844 VEVAFNKVKSLDAEIQQHKKK--NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL 901
+ +++ + +I Q K++ + E +K +E + L ++ +++ ++ L
Sbjct: 1828 DFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKML 1887
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDE---LNE--KLNGINKEELNEKESL 956
++E+ K + + + + L + +K D E +N+ +LNG +
Sbjct: 1888 QEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDA 1947
Query: 957 IIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKM 1004
IK L + +SEL++ + E K + +I K++ EK+
Sbjct: 1948 QIKNELLESEMKNLKKCVSELEEEKQQLVKEKTK-VESEIRKEYLEKI 1994
Score = 47.2 bits (107), Expect = 4e-04
Identities = 97/462 (20%), Positives = 191/462 (41%), Gaps = 35/462 (7%)
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E ++S + +E + MK L EK + + + + Q+ + E + L
Sbjct: 173 EQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRL 232
Query: 673 IEPEQ-KMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD 731
E E ++ T + +M Q+++ + +K E +E V +D+ +
Sbjct: 233 HEDELLQLVTQADVETEMQ------QKLRVLQRKLEEHEESL--VGRAQVVDLLQQELTA 284
Query: 732 FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEESKKQ 790
+Q+ L +++ + + N ++T E+ E++ L ++ NL+E
Sbjct: 285 AEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHH 344
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK 850
L + LE K ++E KT + L + G +++ A +
Sbjct: 345 LLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHIL---SLQKTGQ----ELQSACDA 397
Query: 851 VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
+K ++++ Q K + + + IQ+ D+L +K K+I Q L ++ + E A Q
Sbjct: 398 LKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI---SQFL-NRLPLQQHETASQTS 453
Query: 911 YKRDLDDNLCLRKAQTDITNWQKQDDEL-NEK----LNGINKEEL---NEKESLIIKQTK 962
+ D+ + + +I + QK+ EL NEK L+ I EEL NEK S I +
Sbjct: 454 FP-DVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLE 512
Query: 963 LFQQKAECTGALSELK-KSLKGFRNELEKSLSKDI-EKKFREKMYELHVTKAIDKDIREY 1020
+ E +SE+ + R+ + +D+ E F +K EL V K+ +E
Sbjct: 513 AQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQE- 571
Query: 1021 AVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIK 1062
+A K ++ R + E + ++ + K G I I++K
Sbjct: 572 EIAFLKLQLQGKRAE-EADHEVLDQKEMKQMEGEGIAPIKMK 612
Score = 44.8 bits (101), Expect = 0.002
Identities = 82/417 (19%), Positives = 185/417 (44%), Gaps = 41/417 (9%)
Query: 589 SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE 648
SE N ++ + E ++ S+K +E+ S E T D + LE
Sbjct: 827 SEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLL--LE 884
Query: 649 KRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEA 708
K+ DV+T +T+ E +++T +KM + + + + ++E + + E
Sbjct: 885 KKR-DVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEE 943
Query: 709 VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAK 768
K++ + D+E V++ + ++ + + + Q + + K+ + ++K K +
Sbjct: 944 AKKEQVEEDNE----VSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENE---QRKRKLQ 996
Query: 769 EELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
L+N ++ +Q + LEE L+ + + E+ L E + E +
Sbjct: 997 AALINRKELLQRVSRLEEELANLKDE---------------SKKEIPLSETERGEVEEDK 1041
Query: 829 RNRDLIE-AGSAYIAKVEVAFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQ 886
N++ E ++ ++E+ + S + E++ QH +K++ ++ +E L+++ Q
Sbjct: 1042 ENKEYSEKCVTSKCQEIEIYLKQTIS-EKEVELQHIRKDLEEKL-AAEEQFQALVKQMNQ 1099
Query: 887 IMTDRQVLTKKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGI 945
+ D+ T +ID L+ EI++ Q + ++ + N + D K+ ++ G
Sbjct: 1100 TLQDK---TNQIDLLQAEISENQAIIQKLITSN--TDASDGDSVALVKETVVISPPCTGS 1154
Query: 946 N---KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ K EL EK + K+ + Q+K + AL+ K LK E E+ L ++++++
Sbjct: 1155 SEHWKPELEEKILALEKEKEQLQKKLQ--EALTSRKAILKK-AQEKERHLREELKQQ 1208
Score = 41.1 bits (92), Expect = 0.023
Identities = 121/702 (17%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKE--MIEENLKTKEK- 446
E I E Q +N+ +K V+Q ++ +D ++ K + L++ +I+E K + K
Sbjct: 2156 EETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKF 2215
Query: 447 --------QLIVLKNKHKTALMELLG--NVPEKDFAVTINKFECEVRNEVXXXXXXXXXX 496
+ I LK + + L + L ++ ++ + I++ E + +
Sbjct: 2216 SDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQ 2275
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQ 555
L+ E K + L E R +++++ K + L+ + ++EK ++++
Sbjct: 2276 QKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQK 2335
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
L+ II + + ++++ E + + +N+ K +K+
Sbjct: 2336 GNLEG---IIRQQEADIQNSK---FSYEQLETDLQASRELTSRLHEEINM--KEQKIISL 2387
Query: 616 LQ-RASAKKDEILSMKSLNEK-ITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI-TMSL 672
L + A + I ++ ++K I L++ + E+ IV + K +++T + + T+
Sbjct: 2388 LSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKT 2447
Query: 673 IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQV 730
I+ E A Q+ + + + + ++ ++E+ + + + + A A+
Sbjct: 2448 IKKENIQQKA-QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENN 2506
Query: 731 DFKQKISTLRNRV---KTTQKKLNA----HNKKLQTLYEKKTKAKEELLNTQ-KKVQDIV 782
K++I LR+ + + KL+A + + L + K +++LL Q ++ +++
Sbjct: 2507 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELE 2566
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAK----TEVVRRNRDLIEAGS 838
N ++ + A+ + L ++IE+ +++ R+ L E G+
Sbjct: 2567 NKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGT 2626
Query: 839 A--YIAKVEVAFNKVKSLDAEIQQHKKKNVPREME----------KIQEANDKLMEKQKQ 886
Y A+++V +V L A +K+ E E K+ E DKL ++ K
Sbjct: 2627 LGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKH 2686
Query: 887 IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL----RKAQT--------DITNWQKQ 934
+ D ++ + +T ++ +A+ +++ L + K T +++ Q
Sbjct: 2687 LHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNS 2746
Query: 935 DDELNEKLNGI-NKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLS 993
D NE+L+ + K + + KE +K+ L ++ + LSE S+ L
Sbjct: 2747 RDHANEELDELKRKYDASLKELAQLKEQGLLNRERD--ALLSETAFSMNSTEENSLSHLE 2804
Query: 994 KDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
K ++ + LH++ ++ D + K + E+
Sbjct: 2805 KLNQQLLSKDEQLLHLSSQLE-DSYNQVQSFSKAMASLQNER 2845
Score = 37.9 bits (84), Expect = 0.22
Identities = 96/470 (20%), Positives = 191/470 (40%), Gaps = 40/470 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMK-SLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNET-- 664
+LE+V + + S K ++S K SL+E++ LK + K+ +++ K N+T
Sbjct: 1727 ELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEDNVSKQ-ANLEATEKHDNQTNV 1785
Query: 665 VEEITMSLI-EPEQK----MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS- 718
EE T S+ E E++ M+T +P + + + +D
Sbjct: 1786 TEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQL 1845
Query: 719 -EMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK 777
E + KQ + K+ TL N T +++ + +L+ L E+ TK Q++
Sbjct: 1846 KERIAGLEEEKQKN-KEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEE 1904
Query: 778 VQDIVNLEESKKQLQSDCXXXXXXXXXXXXA--------ITPLEVALKEKIEAKTEVVRR 829
+ + L+E+ ++ + D +T ++ E +E++ + +++
Sbjct: 1905 LSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIK-NELLESEMKNLKK 1963
Query: 830 NRDLIEAGSAYIAKVEVAF-NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ---K 885
+E + K + ++++ E Q +K P +E + L EKQ K
Sbjct: 1964 CVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKE-PGNKSHAKELQELLKEKQQEVK 2022
Query: 886 QIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD--ITNWQKQDDELNEKLN 943
Q+ D +KI L+ + E + + +L + K + + +K EL
Sbjct: 2023 QLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAEL-ASFK 2081
Query: 944 GINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREK 1003
+ + +E ++ KL K E +K +K +LE+ L + EK +EK
Sbjct: 2082 VLLDDTQSEAARVLADNLKL---KKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEK 2138
Query: 1004 --MYE----LHVTKA-IDKDIREYAVALDKCLMEFHREKMENINMIIREL 1046
M E L K +++ I E V L+K E ++ EN++ + +L
Sbjct: 2139 KNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEV-QQLQENLDSTVTQL 2187
Score = 37.1 bits (82), Expect = 0.38
Identities = 26/100 (26%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Query: 219 QKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIA 278
Q E + + + N +E+KI + S E E + + E + Q DK +++
Sbjct: 2364 QASRELTSRLHEEINMKEQKIISLLSGKE-EAIQVAIAELRQQH--DKEIKELENLLSQE 2420
Query: 279 EIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQAD 318
E ENI + N++A + T ++E ++++K ++ QK+Q D
Sbjct: 2421 EEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLD 2460
Score = 33.9 bits (74), Expect = 3.5
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
Query: 192 DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
D+L++ K+ +Q L L A Q D Y + T EE + +K E+E
Sbjct: 425 DQLQQKSKEISQFLNRLPLQQHET-ASQTSFPDVYNEGTQAVTEENIASLQKRVVELENE 483
Query: 252 K-FILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVES 305
K +LL S E++ NE++ + E +N T E +E + I K S
Sbjct: 484 KGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSS 538
>BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex protein
1 protein.
Length = 976
Score = 55.6 bits (128), Expect = 1e-06
Identities = 103/451 (22%), Positives = 199/451 (44%), Gaps = 54/451 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+L+ +T +LQ+ S++ +E+ K+T K+ E+ +L+K + + +T + N+ E+
Sbjct: 404 QLKILTMELQKKSSELEEMT-------KLTNNKEVELEELKKVLGEKETLLYE-NKQFEK 455
Query: 668 ITMSLIEPEQKM-----TTAKQIHGDMPMLDR-------YIQEIKTVTKKFEAVKEQCGD 715
I L EQ++ K++H L Y +E+K + K E E+ +
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL--KTELENEKLKN 513
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
+ + + + + Q+ S + +K Q+ +N +NKK + E+ K E L T+
Sbjct: 514 TELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN-NNKKQE---ERMLKQIENLQETE 569
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
++++ LE +++L+ L ++ K + E+ + N+ L +
Sbjct: 570 TQLRN--ELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKK 627
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREME--KIQEAN-DKLMEKQKQ 886
G+A ++ V KV L+ E++ K+K +E+E KI E N + +EK K
Sbjct: 628 KGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKV 687
Query: 887 IMTDRQVLTKKID-----TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD----- 936
I + L K+ID + + +A E +K D + R ++ + ++Q+
Sbjct: 688 IADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRA 747
Query: 937 ELNEKLNGINKEELNEKESLII---KQTKLFQQKAECTGALSELK-KSLKGFRNELEKSL 992
L +L+ + E L+ K+ L I ++ KL ++ E T L E K K + F E +
Sbjct: 748 SLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIY 807
Query: 993 SKDIEKKFREKMYELHVTK---AIDKDIREY 1020
K K + + T I KD R+Y
Sbjct: 808 WKLDSKAVPSQTVSRNFTSVDHGISKDKRDY 838
Score = 39.9 bits (89), Expect = 0.054
Identities = 53/231 (22%), Positives = 106/231 (45%), Gaps = 20/231 (8%)
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK-SLDAEIQQH----KKKNVP 867
+V+ + ++ K ++ NR +IEA I +++ KV L+ IQ++ K+ N
Sbjct: 120 KVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNAT 179
Query: 868 REM-EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
R + ++E + EK K+ +R+ + L + I K +L + ++
Sbjct: 180 RHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEEL--RVQAENSRL 237
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKES----LIIKQTKLFQQKAECTGALSELKKSLK 982
++ K+D E + L K+E+N+KE L+I+ T+ + + T L E + +
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV- 296
Query: 983 GFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR---EYAVALDKCLME 1030
N+LE+ E + + H+TK ++ DI+ + +V+ K L E
Sbjct: 297 ---NQLEEKTKLQSENLKQSIEKQHHLTKELE-DIKVSLQRSVSTQKALEE 343
Score = 39.9 bits (89), Expect = 0.054
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 211 YATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQ 270
Y+ VK + ELE+ KNT K++ E E + + LE +NQ++ D N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD-MTLELKNQQE-DINNNK 552
Query: 271 IVETAKIAEIENI--TEVQTNEEAENATKTILEKVESLKSDHKVQKSQ 316
E + +IEN+ TE Q E E + + +K + +K K+ KS+
Sbjct: 553 KQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKC--KLDKSE 598
>AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex protein
1 protein.
Length = 976
Score = 55.6 bits (128), Expect = 1e-06
Identities = 103/451 (22%), Positives = 199/451 (44%), Gaps = 54/451 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+L+ +T +LQ+ S++ +E+ K+T K+ E+ +L+K + + +T + N+ E+
Sbjct: 404 QLKILTMELQKKSSELEEMT-------KLTNNKEVELEELKKVLGEKETLLYE-NKQFEK 455
Query: 668 ITMSLIEPEQKM-----TTAKQIHGDMPMLDR-------YIQEIKTVTKKFEAVKEQCGD 715
I L EQ++ K++H L Y +E+K + K E E+ +
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL--KTELENEKLKN 513
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
+ + + + + Q+ S + +K Q+ +N +NKK + E+ K E L T+
Sbjct: 514 TELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN-NNKKQE---ERMLKQIENLQETE 569
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
++++ LE +++L+ L ++ K + E+ + N+ L +
Sbjct: 570 TQLRN--ELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKK 627
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREME--KIQEAN-DKLMEKQKQ 886
G+A ++ V KV L+ E++ K+K +E+E KI E N + +EK K
Sbjct: 628 KGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKV 687
Query: 887 IMTDRQVLTKKID-----TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD----- 936
I + L K+ID + + +A E +K D + R ++ + ++Q+
Sbjct: 688 IADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRA 747
Query: 937 ELNEKLNGINKEELNEKESLII---KQTKLFQQKAECTGALSELK-KSLKGFRNELEKSL 992
L +L+ + E L+ K+ L I ++ KL ++ E T L E K K + F E +
Sbjct: 748 SLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIY 807
Query: 993 SKDIEKKFREKMYELHVTK---AIDKDIREY 1020
K K + + T I KD R+Y
Sbjct: 808 WKLDSKAVPSQTVSRNFTSVDHGISKDKRDY 838
Score = 39.9 bits (89), Expect = 0.054
Identities = 53/231 (22%), Positives = 106/231 (45%), Gaps = 20/231 (8%)
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK-SLDAEIQQH----KKKNVP 867
+V+ + ++ K ++ NR +IEA I +++ KV L+ IQ++ K+ N
Sbjct: 120 KVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNAT 179
Query: 868 REM-EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
R + ++E + EK K+ +R+ + L + I K +L + ++
Sbjct: 180 RHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEEL--RVQAENSRL 237
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKES----LIIKQTKLFQQKAECTGALSELKKSLK 982
++ K+D E + L K+E+N+KE L+I+ T+ + + T L E + +
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV- 296
Query: 983 GFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR---EYAVALDKCLME 1030
N+LE+ E + + H+TK ++ DI+ + +V+ K L E
Sbjct: 297 ---NQLEEKTKLQSENLKQSIEKQHHLTKELE-DIKVSLQRSVSTQKALEE 343
Score = 39.9 bits (89), Expect = 0.054
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 211 YATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQ 270
Y+ VK + ELE+ KNT K++ E E + + LE +NQ++ D N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD-MTLELKNQQE-DINNNK 552
Query: 271 IVETAKIAEIENI--TEVQTNEEAENATKTILEKVESLKSDHKVQKSQ 316
E + +IEN+ TE Q E E + + +K + +K K+ KS+
Sbjct: 553 KQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKC--KLDKSE 598
>AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex protein
1 protein.
Length = 976
Score = 55.6 bits (128), Expect = 1e-06
Identities = 103/451 (22%), Positives = 199/451 (44%), Gaps = 54/451 (11%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+L+ +T +LQ+ S++ +E+ K+T K+ E+ +L+K + + +T + N+ E+
Sbjct: 404 QLKILTMELQKKSSELEEMT-------KLTNNKEVELEELKKVLGEKETLLYE-NKQFEK 455
Query: 668 ITMSLIEPEQKM-----TTAKQIHGDMPMLDR-------YIQEIKTVTKKFEAVKEQCGD 715
I L EQ++ K++H L Y +E+K + K E E+ +
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL--KTELENEKLKN 513
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
+ + + + + Q+ S + +K Q+ +N +NKK + E+ K E L T+
Sbjct: 514 TELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN-NNKKQE---ERMLKQIENLQETE 569
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
++++ LE +++L+ L ++ K + E+ + N+ L +
Sbjct: 570 TQLRN--ELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKK 627
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREME--KIQEAN-DKLMEKQKQ 886
G+A ++ V KV L+ E++ K+K +E+E KI E N + +EK K
Sbjct: 628 KGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKV 687
Query: 887 IMTDRQVLTKKID-----TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD----- 936
I + L K+ID + + +A E +K D + R ++ + ++Q+
Sbjct: 688 IADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRA 747
Query: 937 ELNEKLNGINKEELNEKESLII---KQTKLFQQKAECTGALSELK-KSLKGFRNELEKSL 992
L +L+ + E L+ K+ L I ++ KL ++ E T L E K K + F E +
Sbjct: 748 SLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIY 807
Query: 993 SKDIEKKFREKMYELHVTK---AIDKDIREY 1020
K K + + T I KD R+Y
Sbjct: 808 WKLDSKAVPSQTVSRNFTSVDHGISKDKRDY 838
Score = 39.9 bits (89), Expect = 0.054
Identities = 53/231 (22%), Positives = 106/231 (45%), Gaps = 20/231 (8%)
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK-SLDAEIQQH----KKKNVP 867
+V+ + ++ K ++ NR +IEA I +++ KV L+ IQ++ K+ N
Sbjct: 120 KVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNAT 179
Query: 868 REM-EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
R + ++E + EK K+ +R+ + L + I K +L + ++
Sbjct: 180 RHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEEL--RVQAENSRL 237
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKES----LIIKQTKLFQQKAECTGALSELKKSLK 982
++ K+D E + L K+E+N+KE L+I+ T+ + + T L E + +
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV- 296
Query: 983 GFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR---EYAVALDKCLME 1030
N+LE+ E + + H+TK ++ DI+ + +V+ K L E
Sbjct: 297 ---NQLEEKTKLQSENLKQSIEKQHHLTKELE-DIKVSLQRSVSTQKALEE 343
Score = 39.9 bits (89), Expect = 0.054
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 211 YATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQ 270
Y+ VK + ELE+ KNT K++ E E + + LE +NQ++ D N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD-MTLELKNQQE-DINNNK 552
Query: 271 IVETAKIAEIENI--TEVQTNEEAENATKTILEKVESLKSDHKVQKSQ 316
E + +IEN+ TE Q E E + + +K + +K K+ KS+
Sbjct: 553 KQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKC--KLDKSE 598
>AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens cDNA
FLJ14799 fis, clone NT2RP4001351, weakly similar to Human
ovarian cancer downregulated myosin heavy chain homolog
).
Length = 965
Score = 55.6 bits (128), Expect = 1e-06
Identities = 79/440 (17%), Positives = 184/440 (41%), Gaps = 24/440 (5%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+LE+ ++LQ+A + E+ + E + E+ L KR+++++ + + + +T +
Sbjct: 96 ELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQ 155
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ +++ +K++ ++ L + + E++ + + F K +C + + +
Sbjct: 156 CRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLT 215
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKE---ELLNTQKKVQDIVNL 784
K D ++ +++RVK + + K +L + TK K L++ +K + + +
Sbjct: 216 K--DLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQ 273
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
EE K + L K+ ++ K+E+ + +L I K+
Sbjct: 274 EERK--VDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKL 331
Query: 845 EVAFNKVKSLDAEIQQHKKK-NVPREMEKIQEANDKLMEKQKQIMTDRQV--LTKKIDTL 901
+ K L + KK+ + E+E+ + D ++ LT +I+ L
Sbjct: 332 KSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERL 391
Query: 902 KDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQT 961
K + + EV + D L K + + +++ +K N ++ ++L E + I K
Sbjct: 392 KKRLQQLEVVEGD------LMKTEDEYDQLEQKFRTEQDKANFLS-QQLEEIKHQIAKNK 444
Query: 962 KLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYA 1021
+ +K E +EL+ R LE++ S+D++ + ++H + + +
Sbjct: 445 AI--EKGEVVSQEAELR-----HRFRLEEAKSRDLKAGVQALKEKIHELMNKEDQLSQLQ 497
Query: 1022 VALDKCLMEFHREKMENINM 1041
V F E+ +N NM
Sbjct: 498 VDYSVLQQRFMEEENKNKNM 517
Score = 45.2 bits (102), Expect = 0.001
Identities = 97/535 (18%), Positives = 211/535 (39%), Gaps = 28/535 (5%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+++ Q++ E+E+ ++ + E QK+ KL+ + K +E+ + K L +
Sbjct: 20 VQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVD-FEHKASRFSQEHEEMNAK-LANQE 77
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
+ ++ ++L+G + NK + E+ L AE +++R+
Sbjct: 78 SHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRK 137
Query: 513 SLNE---RRSELTKAEDKIYKACGTQPYDVTLSK-YTTTVEKLQDEQNVLQSSMFIINKY 568
+ E + E+TK E + + + SK VEKLQ + L+ +K
Sbjct: 138 RVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKS 197
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRAS-AKKDEIL 627
K + C + E E + +LE L++A + KD++
Sbjct: 198 KSE------CTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLT 251
Query: 628 SMKSLNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK- 683
+KS + + +I Q E+++ ++ K V ++T LIE +K+ K
Sbjct: 252 KLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS 311
Query: 684 QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI--STLRN 741
++ + L R E+ K ++ +E+ ++ + L K++D +++ R
Sbjct: 312 EMEEKVYNLTRERDEL---IGKLKSEEEKSSELSCSVDL---LKKRLDGIEEVEREITRG 365
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXX 801
R + + + K++ L + + K+ L + D++ E+ QL+
Sbjct: 366 RSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQLEQKFRTEQDK 425
Query: 802 XXXXXXAITPLEVAL-KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ 860
+ ++ + K K K EVV + +L AK V++L +I
Sbjct: 426 ANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEEAKSRDLKAGVQALKEKI-- 483
Query: 861 HKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
H+ N ++ ++Q L ++ + + + +++ L E+ + Y R L
Sbjct: 484 HELMNKEDQLSQLQVDYSVLQQRFMEEENKNKNMGQEVLNLTKELELSKRYSRAL 538
Score = 36.7 bits (81), Expect = 0.50
Identities = 83/424 (19%), Positives = 175/424 (41%), Gaps = 27/424 (6%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
HK + EE ++ E Q ++ L+Q+I +L++ L++ E + L+
Sbjct: 57 HKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRD 116
Query: 444 KEKQLIVLKNKHKTALMELLGNVPE---KDFAVTINKFEC-EVRNEVXXXXXXXXXXXXX 499
K + + + L V E KD +T + +C E+R ++
Sbjct: 117 KIAKGECGNSSLMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLE 176
Query: 500 XXXLE---AERKHIRESLNERRSELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQ 555
L+ +E + + E+ ++ +SE T+ + K T+ L + V++L+ +
Sbjct: 177 VEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 236
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRG--FENESEXXXXXXXXXXXXMNVPGKLEKVT 613
+ L+ + + +LK + + R E + GK+ VT
Sbjct: 237 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 296
Query: 614 EDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSL 672
E L S K +L +KS + EK+ L E +L ++ + + L+ +V+ + L
Sbjct: 297 EKLIEESKK---LLKLKSEMEEKVYNL-TRERDELIGKLKSEEEKSSELSCSVDLLKKRL 352
Query: 673 --IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
IE ++ T + + +IK +T + E +K++ L+V +
Sbjct: 353 DGIEEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRL------QQLEVVEGDLM 406
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK--KTKA--KEELLNTQKKVQDIVNLEE 786
+ + L + +T Q K N +++L+ + + K KA K E+++ + +++ LEE
Sbjct: 407 KTEDEYDQLEQKFRTEQDKANFLSQQLEEIKHQIAKNKAIEKGEVVSQEAELRHRFRLEE 466
Query: 787 SKKQ 790
+K +
Sbjct: 467 AKSR 470
Score = 35.5 bits (78), Expect = 1.2
Identities = 101/595 (16%), Positives = 232/595 (38%), Gaps = 52/595 (8%)
Query: 407 VEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNV 466
V++ + +++L + K+Q T KL+E+E + + +K K+ ++ K +E+
Sbjct: 3 VDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKSKE-----DRQKLLKLEVDFEH 57
Query: 467 PEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAED 526
F+ + ++ N+ +E E + ++L + EL + D
Sbjct: 58 KASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIE-ELEETNKNLQKAEEELQELRD 116
Query: 527 KIYKA-CGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGF 585
KI K CG S VE L+ + VL+ K + K S C +
Sbjct: 117 KIAKGECGN-------SSLMAEVENLR--KRVLEME----GKDEEITKTESQCRELRKKL 163
Query: 586 ENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIP 645
+ E +LEK+ E ++ ++ ++ + +T E+
Sbjct: 164 QEEEHHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELE 223
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
++ R+ +++ L + E+++ + K T + M+++ QE + V
Sbjct: 224 VVKSRVKELECSESRLEKA--ELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGL 281
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKL-QTLYEKK 764
+ K + G V +DV T K ++ +K+ L++ ++ L +L L ++
Sbjct: 282 NKNFKVEQGKV-----MDV-TEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEE 335
Query: 765 TKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT 824
K+ E + + + +EE ++++ P + +KE + +
Sbjct: 336 EKSSELSCSVDLLKKRLDGIEEVEREI------TRGRSRKGSELTCPEDNKIKE-LTLEI 388
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKI--QEANDKLME 882
E +++ +E + K E +++++ +Q K + +++E+I Q A +K +E
Sbjct: 389 ERLKKRLQQLEVVEGDLMKTEDEYDQLEQ-KFRTEQDKANFLSQQLEEIKHQIAKNKAIE 447
Query: 883 KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNL-CLRKAQTDITNWQKQDDELNEK 941
K + + + + L+ +E RDL + L++ ++ N + Q +L
Sbjct: 448 KGEVVSQEAE--------LRHRFRLEEAKSRDLKAGVQALKEKIHELMNKEDQLSQLQVD 499
Query: 942 LNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
+ + + + E+ K + Q+ T L K+ + R + D+
Sbjct: 500 YSVLQQRFMEEEN----KNKNMGQEVLNLTKELELSKRYSRALRPSVNGKRMVDV 550
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 55.2 bits (127), Expect = 1e-06
Identities = 108/610 (17%), Positives = 256/610 (41%), Gaps = 62/610 (10%)
Query: 385 KQAENEL--NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLK 442
+Q + EL + + E EK +++ EQEM+E+ +K+ K AK K+++++E
Sbjct: 1606 RQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF----AKSKQQKILE---- 1657
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXX 502
+ +N A + G+ K+ T+ ++ E+
Sbjct: 1658 ------LEEENDRLRAEVHPAGDT-AKECMETLLSSNASMKEELERVKMEYETLSKKFQS 1710
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGTQPYD----VTLSKYTTTVEKLQDEQNVL 558
L +E+ + E + + + ++ K T+ +D VT + + +++ ++
Sbjct: 1711 LMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLS 1770
Query: 559 QSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR 618
S+ ++ K S P ++ F + E + G E+ ++ +
Sbjct: 1771 MSTRPTCSESVPSAK--SANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEF 1828
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
+ ++E +L +I+T KD E+ L++ + T++ LN+ ++E L +
Sbjct: 1829 SQTLENE---KNTLLSQIST-KDGELKMLQEEV----TKMNLLNQQIQE---ELSRVTKL 1877
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDV-DSEMTLDVATAKQVDFKQKIS 737
TA++ D+ +R + ++ + ++ C DV D+++ ++ ++ + K+ +S
Sbjct: 1878 KETAEEEKDDLE--ERLMNQLAELN---GSIGNYCQDVTDAQIKNELLESEMKNLKKCVS 1932
Query: 738 TLRNRVKTTQKKLNAHNKKLQTLY-EKKTKAKEELLNTQ--KKVQDIVNLEESK-KQLQS 793
L + K+ +++ Y EK A++E N K++Q+++ ++ + KQLQ
Sbjct: 1933 ELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 1992
Query: 794 DCXXXXXXXXXXXXAITPLEVALKEK---IEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK 850
DC + LE E +E E + + + + A +A +V +
Sbjct: 1993 DCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDD 2052
Query: 851 VKS-----------LDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKID 899
+S L E+Q +K+ + +K ++ +L + +++ + +++ + +K+D
Sbjct: 2053 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLD 2112
Query: 900 TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--EELNEKESLI 957
L+ E K + + + + L K ++ Q+ D +L K L + +
Sbjct: 2113 ALRRE--KVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRV 2170
Query: 958 IKQTKLFQQK 967
I + K +++K
Sbjct: 2171 IDEAKKWERK 2180
Score = 54.8 bits (126), Expect = 2e-06
Identities = 97/433 (22%), Positives = 192/433 (44%), Gaps = 45/433 (10%)
Query: 611 KVTEDLQRASAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
++ L+ A+K E+ L + S ++T K E+ QL+++I +I++L E
Sbjct: 1272 QIKAQLKEIEAEKVELELKVSSTTSELTK-KSEEVFQLQEQINKQGLEIESLKTVSHEAE 1330
Query: 670 MSLIEPEQKMTTAK-QIHG--DMPMLDRYIQEI-KTVTKKFEAVKEQCGDV-DSEMTLDV 724
+ +QK+ +++ QI G + L + E+ K ++KK E V G + + E L
Sbjct: 1331 VHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTK 1390
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+ ++ + I L +++ K+ + K+LQ EL ++K ++I
Sbjct: 1391 IQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQV----------ELCEMKQKPEEIGEE 1440
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
+K+Q+Q A+ + ALKE ++ E + R IE + +A V
Sbjct: 1441 SRAKQQIQ----------RKLQAALISRKEALKEN-KSLQEELSLARGTIERLTKSLADV 1489
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
E ++V + Q +K V + +QE DKL+ + + + + Q L+ ++LK
Sbjct: 1490 E---SQVSA-----QNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLA 1541
Query: 905 IAKQEVYKRDLDDNLCLRKAQ--TDITNWQKQDDELNEKLNGI--NKEEL-NEKESLIIK 959
+ K L + K+ + T WQ++ EL ++ + + E + NE E +
Sbjct: 1542 LEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHV 1601
Query: 960 QTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
+ Q+K E G L + + K +L+++ +++E + +EKM + K+ + I E
Sbjct: 1602 VEAVRQEKQELYGKLRSTEANKKETEKQLQEA-EQEME-EMKEKMRKF--AKSKQQKILE 1657
Query: 1020 YAVALDKCLMEFH 1032
D+ E H
Sbjct: 1658 LEEENDRLRAEVH 1670
Score = 54.8 bits (126), Expect = 2e-06
Identities = 117/637 (18%), Positives = 252/637 (39%), Gaps = 60/637 (9%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQ-KQTAKLKEKEMIEENLK 442
H + EL ++E QQE+ + +K +Y++++ L + + L+ QT K+ E+ +ENL
Sbjct: 1972 HAKELQEL-LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLA 2030
Query: 443 TKEKQLIVLKNKHKTALMELLGNVPEKDFAVTIN-----KFECEVRNEVXXXXXXXXXXX 497
+ K + + A ++L + + + A + K E + E
Sbjct: 2031 QAVEHR--KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDED 2088
Query: 498 XXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNV 557
+AE KH++E N + +K++ VTL+K V++LQ+ +
Sbjct: 2089 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDS 2148
Query: 558 LQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQ 617
+ + K L+D+ +R + + + K E++
Sbjct: 2149 TVTQLAAFTKSMSSLQDDR-----DRVIDEAKKWERKFSDA------IQSKEEEIRLKED 2197
Query: 618 RASAKKDEI----LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLI 673
S KD++ + M+ L I+ L+ + K +V Q K + E L
Sbjct: 2198 NCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLS 2257
Query: 674 EPEQKMTTAKQIHGDMPMLDRYIQEIK----TVTKKFEAVKEQCGDVDS---EMTLDVAT 726
+ E+ ++ L+ ++ +K ++ E KEQ G+++ + D+
Sbjct: 2258 QLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQN 2317
Query: 727 AK--QVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
+K + + R +++N +K+ +L K +A + + ++ D +
Sbjct: 2318 SKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHD-KEI 2376
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV 844
+E + L + A+ ++ K E +++ L +++ +
Sbjct: 2377 KELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL----DSFVKSM 2432
Query: 845 EVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
N + + QQ +++++ +EK Q + E K + + + L +D L E
Sbjct: 2433 SSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNK-LKEEIRGLRSHMDDLNSE 2491
Query: 905 IAKQEV----YKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQ 960
AK + Y+ DL+ + ++ +Q QKQ + + +L + + L K
Sbjct: 2492 NAKLDAELIQYREDLNQVITIKDSQ------QKQ----------LLEVQLQQNKELENKY 2535
Query: 961 TKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE 997
KL ++ E A +L++S + E ++ LSK+IE
Sbjct: 2536 AKLEEKLKESEEANEDLRRSFNALQEE-KQDLSKEIE 2571
Score = 54.4 bits (125), Expect = 2e-06
Identities = 70/358 (19%), Positives = 166/358 (46%), Gaps = 44/358 (12%)
Query: 610 EKVTEDLQRAS-AKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI 668
+++ LQ A ++K+ + KSL E+++ + T I +L K + DV++Q+ N+ + +
Sbjct: 1445 QQIQRKLQAALISRKEALKENKSLQEELSLARGT-IERLTKSLADVESQVSAQNKEKDTV 1503
Query: 669 T--MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++L++ E+ + +DR + E ++++ E++K + L+ T
Sbjct: 1504 LGRLALLQEERDKLITE--------MDRSLLENQSLSSSCESLK---------LALEGLT 1546
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LE 785
+ ++I +L++ + +K+LQ YE ++ E + N +++Q +V +
Sbjct: 1547 EDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVR 1606
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVE 845
+ K++L E L+E + E+ + R ++ I ++E
Sbjct: 1607 QEKQELYGKLRSTEANKKET-------EKQLQEAEQEMEEMKEKMRKFAKSKQQKILELE 1659
Query: 846 VAFNKVKSLDAEIQQHKKKNVPRE-MEKIQEANDKLMEKQKQIMTDRQVLTKKIDTL--- 901
++++ AE+ H + +E ME + +N + E+ +++ + + L+KK +L
Sbjct: 1660 EENDRLR---AEV--HPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSE 1714
Query: 902 KDEIAKQ-EVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--EELNEKESL 956
KD ++++ + K ++ N+ Q ++ +K D++ N G E E++SL
Sbjct: 1715 KDSLSEEVQDLKHQIEGNV---SKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSL 1769
Score = 48.4 bits (110), Expect = 2e-04
Identities = 159/878 (18%), Positives = 356/878 (40%), Gaps = 76/878 (8%)
Query: 85 KIVNAKDKQLEVTRSM--KVTALAKKKTKFQ-TLDSFLSTVDESGKTKDVSSRCADLDIL 141
++ A++K L+ ++M K+ AL ++K + T+ T+++ K K+V +LD
Sbjct: 2092 RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK--KDKEVQQLQENLDST 2149
Query: 142 MHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDY 201
+ + +K+ ++S+ Q+D +DE KK + +F DA + + RLK+
Sbjct: 2150 VTQLAAFTKS-MSSL----QDDRDRVIDEAKKWERKFS---DAIQSKEEEIRLKE----- 2196
Query: 202 AQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFIL--LESQ 259
N +L++ + +EL K N S + +++I K+ E++ + + L+ +
Sbjct: 2197 -DNCSVLKDQLRQMSIHMEEL----KINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGE 2251
Query: 260 NQEKIDKRNE--QIVETAK--IAEIENITEVQTNEEAENATKTILEKVESLKSDHK--VQ 313
N+E + + E + +++ +A++E+ E+++ ++ LEK + K + + ++
Sbjct: 2252 NKELLSQLEETRHLYHSSQNELAKLES--ELKSLKDQLTDLSNSLEKCKEQKGNLEGIIR 2309
Query: 314 KSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXX 373
+ +AD + K F E Q + S +
Sbjct: 2310 QQEADIQNSK---FSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIA 2366
Query: 374 XXXXXXXXXXHKQAENELNIEECQQEINEDE--KAVEQYEQEMDELSQKITKLQKQTAKL 431
K+ EN L+ EE + + E+E KAV++ Q M+ L + +Q A+L
Sbjct: 2367 ELRQQHDKEI-KELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL 2425
Query: 432 KEKEMIEENLKTKEKQLI----VLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVX 487
+L+ +++ L+ +H + ++E + E A NK + E+R
Sbjct: 2426 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEA--AAENNKLKEEIRG--- 2480
Query: 488 XXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTT 547
L+AE RE LN+ + + ++ + Q ++ +KY
Sbjct: 2481 -LRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELE-NKYAKL 2538
Query: 548 VEKLQDEQNV---LQSSMFIINKYKGQL-KDNSCCPLCNRGFENESEXXXXXXXXXXXXM 603
EKL++ + L+ S + + K L K+ + +
Sbjct: 2539 EEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHA 2598
Query: 604 NVPGKLEKV-------TEDLQRASAKKDEILSM-KSLNEKITTLKDT---EIPQLEKRIV 652
+ K E+V + +R + ++E++ + K +K+ ++D E+ L
Sbjct: 2599 QLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAG 2658
Query: 653 DVDTQIKTLNETVEEITMSLIEPEQK-MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
+ + +T E V E+ L+E EQK + K+ G + + + + ++ + E
Sbjct: 2659 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRDHANE 2718
Query: 712 QCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL 771
+ ++ + D + + K++ R R + + N + K ++L
Sbjct: 2719 ELDEL--KRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQL 2776
Query: 772 LNTQKKVQDIVN-LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
L+ +++ + + LE+S Q+QS L EK E +R+
Sbjct: 2777 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL-----EKFRKSEEGKQRS 2831
Query: 831 RDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD 890
A + ++ A + +++ D + + KN+ ++ +I + +L + Q+ +
Sbjct: 2832 AAQPSTSPAEVQSLKKAMSSLQN-DRDRLLKELKNLQQQYLQINQEITELHPLKAQLQ-E 2889
Query: 891 RQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDI 928
Q TK +++E+ ++ + + D L + K+ +I
Sbjct: 2890 YQDKTKAFQIMQEELRQENLSWQHELDQLRMEKSSWEI 2927
Score = 48.0 bits (109), Expect = 2e-04
Identities = 95/462 (20%), Positives = 193/462 (41%), Gaps = 30/462 (6%)
Query: 614 EDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLI 673
E ++S + +E + MK ++ T QL + + Q+ ++ + V E +
Sbjct: 134 EQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKD-ARF 192
Query: 674 EPEQKMTTAK--QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD 731
E + ++ + Q+ + Q+++ + +K E +E V +D+ +
Sbjct: 193 ETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESL--VGRAQVVDLLQQELTA 250
Query: 732 FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-LNTQKKVQDIVNLEESKKQ 790
+Q+ L +++ + + N ++T E+ E++ L ++ NL+E
Sbjct: 251 AEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHH 310
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK 850
L + LE K ++E KT + L + G +++ A +
Sbjct: 311 LLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHIL---SLQKTGQ----ELQSACDA 363
Query: 851 VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
+K ++++ Q K + + + IQ+ D+L +K K+I Q L ++ + E A Q
Sbjct: 364 LKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI---SQFL-NRLPLQQHETASQTS 419
Query: 911 YKRDLDDNLCLRKAQTDITNWQKQDDEL-NEK----LNGINKEEL---NEKESLIIKQTK 962
+ D+ + + +I + QK+ EL NEK L+ I EEL NEK S I +
Sbjct: 420 FP-DVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLE 478
Query: 963 LFQQKAECTGALSELK-KSLKGFRNELEKSLSKDI-EKKFREKMYELHVTKAIDKDIREY 1020
+ E +SE+ + R+ + +D+ E F +K EL V K+ +E
Sbjct: 479 AQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQE- 537
Query: 1021 AVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIK 1062
+A K ++ R + E + ++ + K G I I++K
Sbjct: 538 EIAFLKLQLQGKRAE-EADHEVLDQKEMKQMEGEGIAPIKMK 578
Score = 44.8 bits (101), Expect = 0.002
Identities = 82/417 (19%), Positives = 185/417 (44%), Gaps = 41/417 (9%)
Query: 589 SEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE 648
SE N ++ + E ++ S+K +E+ S E T D + LE
Sbjct: 793 SEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLL--LE 850
Query: 649 KRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEA 708
K+ DV+T +T+ E +++T +KM + + + + ++E + + E
Sbjct: 851 KKR-DVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEE 909
Query: 709 VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAK 768
K++ + D+E V++ + ++ + + + Q + + K+ + ++K K +
Sbjct: 910 AKKEQVEEDNE----VSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENE---QRKRKLQ 962
Query: 769 EELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
L+N ++ +Q + LEE L+ + + E+ L E + E +
Sbjct: 963 AALINRKELLQRVSRLEEELANLKDE---------------SKKEIPLSETERGEVEEDK 1007
Query: 829 RNRDLIE-AGSAYIAKVEVAFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQ 886
N++ E ++ ++E+ + S + E++ QH +K++ ++ +E L+++ Q
Sbjct: 1008 ENKEYSEKCVTSKCQEIEIYLKQTIS-EKEVELQHIRKDLEEKL-AAEEQFQALVKQMNQ 1065
Query: 887 IMTDRQVLTKKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGI 945
+ D+ T +ID L+ EI++ Q + ++ + N + D K+ ++ G
Sbjct: 1066 TLQDK---TNQIDLLQAEISENQAIIQKLITSN--TDASDGDSVALVKETVVISPPCTGS 1120
Query: 946 N---KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKK 999
+ K EL EK + K+ + Q+K + AL+ K LK E E+ L ++++++
Sbjct: 1121 SEHWKPELEEKILALEKEKEQLQKKLQ--EALTSRKAILKK-AQEKERHLREELKQQ 1174
Score = 41.1 bits (92), Expect = 0.023
Identities = 121/702 (17%), Positives = 287/702 (40%), Gaps = 68/702 (9%)
Query: 390 ELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKE--MIEENLKTKEK- 446
E I E Q +N+ +K V+Q ++ +D ++ K + L++ +I+E K + K
Sbjct: 2122 EETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKF 2181
Query: 447 --------QLIVLKNKHKTALMELLG--NVPEKDFAVTINKFECEVRNEVXXXXXXXXXX 496
+ I LK + + L + L ++ ++ + I++ E + +
Sbjct: 2182 SDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQ 2241
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKA-CGTQPYDVTLSKYTTTVEKLQDEQ 555
L+ E K + L E R +++++ K + L+ + ++EK ++++
Sbjct: 2242 QKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQK 2301
Query: 556 NVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED 615
L+ II + + ++++ E + + +N+ K +K+
Sbjct: 2302 GNLEG---IIRQQEADIQNSK---FSYEQLETDLQASRELTSRLHEEINM--KEQKIISL 2353
Query: 616 LQ-RASAKKDEILSMKSLNEK-ITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEI-TMSL 672
L + A + I ++ ++K I L++ + E+ IV + K +++T + + T+
Sbjct: 2354 LSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKT 2413
Query: 673 IEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQV 730
I+ E A Q+ + + + + ++ ++E+ + + + + A A+
Sbjct: 2414 IKKENIQQKA-QLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQLIQEAAAENN 2472
Query: 731 DFKQKISTLRNRV---KTTQKKLNA----HNKKLQTLYEKKTKAKEELLNTQ-KKVQDIV 782
K++I LR+ + + KL+A + + L + K +++LL Q ++ +++
Sbjct: 2473 KLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELE 2532
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAK----TEVVRRNRDLIEAGS 838
N ++ + A+ + L ++IE+ +++ R+ L E G+
Sbjct: 2533 NKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGT 2592
Query: 839 A--YIAKVEVAFNKVKSLDAEIQQHKKKNVPREME----------KIQEANDKLMEKQKQ 886
Y A+++V +V L A +K+ E E K+ E DKL ++ K
Sbjct: 2593 LGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKH 2652
Query: 887 IMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL----RKAQT--------DITNWQKQ 934
+ D ++ + +T ++ +A+ +++ L + K T +++ Q
Sbjct: 2653 LHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNS 2712
Query: 935 DDELNEKLNGI-NKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLS 993
D NE+L+ + K + + KE +K+ L ++ + LSE S+ L
Sbjct: 2713 RDHANEELDELKRKYDASLKELAQLKEQGLLNRERD--ALLSETAFSMNSTEENSLSHLE 2770
Query: 994 KDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
K ++ + LH++ ++ D + K + E+
Sbjct: 2771 KLNQQLLSKDEQLLHLSSQLE-DSYNQVQSFSKAMASLQNER 2811
Score = 37.5 bits (83), Expect = 0.29
Identities = 81/375 (21%), Positives = 163/375 (43%), Gaps = 42/375 (11%)
Query: 692 LDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQK--- 748
++ Y+Q+I + ++ ++E+ + E + + K Q IST +K Q+
Sbjct: 1801 INNYLQQIDQLKERIAGLEEE-KQKNKEFSQTLENEKNTLLSQ-ISTKDGELKMLQEEVT 1858
Query: 749 KLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD-----IVNLEESKKQLQSDCXXXXXXXX 803
K+N N+++Q + TK KE + +++ + L S D
Sbjct: 1859 KMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNE 1918
Query: 804 XXXXAITPLEVALKEKIEAKTEVVRRNRDL-IEAGSAYIAKVEVAFNKV--KSLDAEIQQ 860
+ L+ + E E K ++V+ + E Y+ K++ A + KS E+Q+
Sbjct: 1919 LLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQE 1978
Query: 861 HKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ-EVYKRDLDDNL 919
K+ +E++++Q+ D + ++K +R V K ++ ++ E K E+ K +L +
Sbjct: 1979 LLKEK-QQEVKQLQK--DCIRYQEKISALERTV--KALEFVQTESQKDLEITKENLAQAV 2033
Query: 920 CLRK-AQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELK 978
RK AQ ++ +++ D+ + + + L K+ L Q E +K
Sbjct: 2034 EHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKEL--------QSNKE------SVK 2079
Query: 979 KSLKGFRNELEKSLSKDIEKKFREK--MYE----LHVTKA-IDKDIREYAVALDKCLMEF 1031
+K +LE+ L + EK +EK M E L K +++ I E V L+K E
Sbjct: 2080 SQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEV 2139
Query: 1032 HREKMENINMIIREL 1046
++ EN++ + +L
Sbjct: 2140 -QQLQENLDSTVTQL 2153
Score = 33.9 bits (74), Expect = 3.5
Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
Query: 192 DRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYN 251
D+L++ K+ +Q L L A Q D Y + T EE + +K E+E
Sbjct: 391 DQLQQKSKEISQFLNRLPLQQHET-ASQTSFPDVYNEGTQAVTEENIASLQKRVVELENE 449
Query: 252 K-FILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVES 305
K +LL S E++ NE++ + E +N T E +E + I K S
Sbjct: 450 KGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSS 504
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 55.2 bits (127), Expect = 1e-06
Identities = 89/416 (21%), Positives = 183/416 (43%), Gaps = 44/416 (10%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 915 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 974
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGD 715
++K L E + + + + ++ ++ H + D ++E K + VK +
Sbjct: 975 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAH-QQALDDLQVEEDKVNSLSKSKVKLEQQV 1033
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKK-LNAHNKKLQTLYEKKTKAKEELLNT 774
D E +L+ ++D ++ L +K TQ+ ++ N KLQ E+K K KE +N
Sbjct: 1034 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQ--LEEKLKKKEFDINQ 1091
Query: 775 Q-KKVQD--IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNR 831
Q K++D ++ L+ KK ++ +V K + + E+ +
Sbjct: 1092 QNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVE-KLRSDLSRELEEISE 1150
Query: 832 DLIEAGSAYIAKVEV------AFNKV-KSLDAEIQQH-------KKKN------VPREME 871
L EAG A ++E+ F K+ + L+ QH +KK+ + +++
Sbjct: 1151 RLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 872 KIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD-----NLCLRKAQT 926
+Q KL +++ + + +T ++ + A E R L+D + L +AQ
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
+ ++ Q +L + NG +L EKE+LI ++L + K T + +LK+ L+
Sbjct: 1271 SLNDFTTQRAKLQTE-NGELARQLEEKEALI---SQLTRGKLSYTQQMEDLKRQLE 1322
Score = 54.0 bits (124), Expect = 3e-06
Identities = 158/853 (18%), Positives = 346/853 (40%), Gaps = 83/853 (9%)
Query: 168 LDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSY 226
L E + E +E +A++ + +++K+R D ++ L+ + E A ++E +
Sbjct: 1110 LKENQARIEELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNK 1167
Query: 227 KKNTSFNK-----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAE 279
K+ F K EE + +E ++ + K ++ E+ID +R +Q +E K
Sbjct: 1168 KREAEFQKMRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEF 1226
Query: 280 IENITEVQTNEEAENATKTILEKVE-SLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQX 338
+ +V +N E K LEKV +L+ + + +E ++ F + T+
Sbjct: 1227 KLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTEN 1286
Query: 339 XXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQ 398
++ Q +A+N L Q
Sbjct: 1287 GELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEG--------KAKNAL-AHALQS 1337
Query: 399 EINEDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKH 455
++ + EQYE+E + EL + ++K + A+ + K + +T+E + +
Sbjct: 1338 ARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE------EA 1391
Query: 456 KTALMELLGNVPEKDFAV-----TINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
K L + L + E AV ++ K + ++NE+ L+ ++++
Sbjct: 1392 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1451
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQD--EQNVLQSSMFIINKY 568
+ L E + + +++ ++ + Q +LS T + KL++ E+++ F
Sbjct: 1452 DKILAEWKQKYEESQSELESS---QKEARSLS---TELFKLKNAYEESLEHLETFKRENK 1505
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KD 624
Q + + G +N E + + LE+ L+ K +
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMT-TAK 683
E +K+ E+ KD E+ Q ++ V ++T + ++ ++KM
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 684 QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRV 743
++ + +R E + K +++ + D+++ LD A D K+ I+ + R
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLK-----DTQIQLDDAVRANDDLKENIAIVERRN 1680
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXX 799
Q +L ++ + A++EL+ T ++VQ + +L KK+++SD
Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESD----- 1735
Query: 800 XXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQ 859
+T L+ ++E ++ + + I +A +A+ K + A ++
Sbjct: 1736 ---------LTQLQSEVEEAVQECRNAEEKAKKAI-TDAAMMAE---ELKKEQDTSAHLE 1782
Query: 860 QHKKKNVPREMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDN 918
+ KKN+ + ++ +Q D+ + K Q L ++ L+ E+ ++ KR+ +
Sbjct: 1783 R-MKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQ--KRNAESV 1839
Query: 919 LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELK 978
+RK++ I Q +E +K N + ++L +K L +K K ++AE A + L
Sbjct: 1840 KGMRKSERRIKELTYQTEE--DKKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLS 1896
Query: 979 KSLKGFRNELEKS 991
K K ++EL+++
Sbjct: 1897 KFRK-VQHELDEA 1908
Score = 53.2 bits (122), Expect = 5e-06
Identities = 137/732 (18%), Positives = 293/732 (40%), Gaps = 86/732 (11%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQKI------TKLQKQTAKL 431
K EN+ IEE ++E+ + EK +E++E+S+++ T +Q + K
Sbjct: 1109 KLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKK 1168
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E L+ KH ++ EL + + + K + E +
Sbjct: 1169 REAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 1228
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + NE R +L +A+ +L+ +
Sbjct: 1229 ELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR-------------SLNDF 1275
Query: 545 TTTVEKLQDEQNVL-----QSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXX 599
TT KLQ E L + I +G+L R E E +
Sbjct: 1276 TTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHAL 1335
Query: 600 XXXMN----VPGKLEKVTE---DLQRASAK-KDEILSMKSLNEKITTLKDTEIPQLEKRI 651
+ + + E+ TE +LQR +K E+ ++ E + E+ + +K++
Sbjct: 1336 QSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1395
Query: 652 VDVDTQIKTLNETVEEITMSLIEPEQ-KMTTAKQIHGDMPMLDRYIQEIKTVTKK---FE 707
+++ E VE + E+ K +I M ++R + KK F+
Sbjct: 1396 AQ---RLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1452
Query: 708 AVKEQCGD--VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
+ + +S+ L+ + + ++ L+N + + + L ++ + L E+ +
Sbjct: 1453 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1512
Query: 766 KAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE-KI 820
E+L K V ++ LE K +LQS I ++ + K
Sbjct: 1513 DLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1572
Query: 821 EAKTEVVRRNRDLIEAGSAY---IAKVEVAFNKVKSLDAEIQQHKKK--NVPREME-KIQ 874
E + ++ ++ ++ +A + + ++ + + E+ + KKK EME ++
Sbjct: 1573 EIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLS 1632
Query: 875 EANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL---DDNLCLRKAQTDITNW 931
AN E QKQ+ + + +L L D + + K ++ + L +A+ +
Sbjct: 1633 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1692
Query: 932 QKQDDELNEKLNGINKEELNEKESLIIKQ-TKLFQQK----AECTGALSELKKSLKGFRN 986
+ E + KL E +E+ L+ Q T L QK ++ T SE++++++ RN
Sbjct: 1693 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRN 1752
Query: 987 ELEKS---------LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKC---LMEFHRE 1034
EK+ ++++++K+ + + K +++ I++ LD+ ++ ++
Sbjct: 1753 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1812
Query: 1035 KMENINMIIREL 1046
+++ + +REL
Sbjct: 1813 QLQKLEARVREL 1824
Score = 41.5 bits (93), Expect = 0.018
Identities = 66/360 (18%), Positives = 150/360 (41%), Gaps = 30/360 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
+ EK + + + + ET+E+ E E+KM + Q D+ +
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDL---------------Q 890
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQK---KLNAHNKKLQTLYE 762
+ EQ D+E D ++ + K+ + R++ ++ +L A +KL+
Sbjct: 891 LQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECS 950
Query: 763 KKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEA 822
+ K ++L T KV+ + E+K + + +T + AL+E +
Sbjct: 951 ELKKDIDDLELTLAKVEKEKHATENKVK---NLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 823 KTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQ-EANDKL- 880
+ ++ D + + S K+E +V L+ ++Q KK + E K + E + KL
Sbjct: 1008 ALDDLQVEEDKVNSLSKSKVKLE---QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1064
Query: 881 MEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE 940
E + D+ L +K+ + +I +Q + D+ + + Q + Q + +EL E
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQN--SKIEDEQVLALQLQKKLKENQARIEELEE 1122
Query: 941 KLNG--INKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+L + ++ + S + ++ + ++ E G + ++ + R + + +D+E+
Sbjct: 1123 ELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1182
Score = 33.5 bits (73), Expect = 4.7
Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 6/162 (3%)
Query: 170 EGKKVKERFDEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKK 228
E K ++E + D D ++ L K + Q + LE K + +LE + +K
Sbjct: 997 EKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRK 1056
Query: 229 -NTSFNKEEEKIA---NEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENIT 284
+E I N+K E + K +Q KI+ ++ K + EN
Sbjct: 1057 LEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLK-ENQA 1115
Query: 285 EVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQG 326
++ EE A +T KVE L+SD + + E ++A G
Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 1157
>AF273042-1|AAG34902.1| 685|Homo sapiens CTCL tumor antigen se1-1
protein.
Length = 685
Score = 55.2 bits (127), Expect = 1e-06
Identities = 94/446 (21%), Positives = 191/446 (42%), Gaps = 51/446 (11%)
Query: 625 EILSMKSLNEK-ITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAK 683
E+ S+K ++K I+ L +T + EK + + +I+ L E E + E ++ + +
Sbjct: 170 EVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQ---EKQEAILNYE 226
Query: 684 QIHGDMPMLDRYIQEIK-TVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNR 742
+ M +L + E ++++FE++K+Q E+ + TA F +K + L
Sbjct: 227 SLREIMEILQTELGESAGKISQEFESMKQQQASDVHELQQKLRTA----FTEKDALLE-- 280
Query: 743 VKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD-IVNLEESKKQLQSDCXXXXXX 801
T +L N+KL + E + + + N Q+K +++L + L+
Sbjct: 281 ---TVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSL 337
Query: 802 XXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
I L+ + +E + R R ++E G KVE L+ ++ +
Sbjct: 338 TEEKDDFINKLKNSHEEMDNFHKKCEREERLILELGK----KVEQTIQYNSELEQKVNEL 393
Query: 862 KK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE----IAKQEVYKRDL 915
+ +E ++ + +KLM + K + D++VL+ ++ +L +E + K++ RDL
Sbjct: 394 TGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEETINSVQKKKQLSRDL 453
Query: 916 DDNLCLRK---AQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLF-------- 964
+ L ++ + IT +K+ + E+ + +NK NE+ + +T+L+
Sbjct: 454 EVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKEMGS 513
Query: 965 ---------------QQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
Q E ++E K +L R+E L K+I+ E + +
Sbjct: 514 EVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEE 573
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREK 1035
K++ +D + V L K L E EK
Sbjct: 574 LKSLLRDYEQEKVLLRKELEEIQSEK 599
Score = 34.7 bits (76), Expect = 2.0
Identities = 43/217 (19%), Positives = 96/217 (44%), Gaps = 12/217 (5%)
Query: 102 VTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHEELGVSKAILNSVV---F 158
+ ++ KKK + L+ FLS ++ + ++ L +++ E+ ++K + N V F
Sbjct: 440 INSVQKKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLF 499
Query: 159 CHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKD-----YAQNLKLLENYAT 213
+ + + G +V E +E + + L KI ++ + ++ K+LE
Sbjct: 500 VKTQLYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINEEKCNLAFQRDEKVLE-LEK 558
Query: 214 TVKAKQKE--LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQI 271
+K Q+E ++ K+ + E+EK+ K EI+ K L + K ++
Sbjct: 559 EIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRL 618
Query: 272 VETAKIAEIENITEVQTNEEAEN-ATKTILEKVESLK 307
+ ++E +++ + E N K +++ E+LK
Sbjct: 619 ENQNLLIQVEEVSQTCSKSEIHNEKEKCFIKEHENLK 655
Score = 33.5 bits (73), Expect = 4.7
Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 395 ECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKE-KEMIEENLKTKEKQLIVLKN 453
E +Q++NE +E+ +E D+ QK+ KL Q L E KE++ +K+ ++ I
Sbjct: 385 ELEQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEETINSVQ 444
Query: 454 KHKTALMEL 462
K K +L
Sbjct: 445 KKKQLSRDL 453
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 54.8 bits (126), Expect = 2e-06
Identities = 89/415 (21%), Positives = 182/415 (43%), Gaps = 42/415 (10%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 915 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATE 974
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGD 715
++K L E + + + + ++ ++ H + D ++E K + VK +
Sbjct: 975 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAH-QQALDDLQVEEDKVNSLSKSKVKLEQQV 1033
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKK-LNAHNKKLQTLYEKKTKAKEELLNT 774
D E +L+ ++D ++ L +K TQ+ ++ N KLQ E+K K KE +N
Sbjct: 1034 DDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQ--LEEKLKKKEFDINQ 1091
Query: 775 Q-KKVQDIVNLE-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
Q K++D L + +K+L+ + T K + + E+ +
Sbjct: 1092 QNSKIEDEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISER 1151
Query: 833 LIEAGSAYIAKVEV------AFNKV-KSLDAEIQQH-------KKKN------VPREMEK 872
L EAG A ++E+ F K+ + L+ QH +KK+ + +++
Sbjct: 1152 LEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDN 1211
Query: 873 IQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD-----NLCLRKAQTD 927
+Q KL +++ + + +T ++ + A E R L+D + L +AQ
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 928 ITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLK 982
+ ++ Q +L + NG +L EKE+LI ++L + K T + +LK+ L+
Sbjct: 1272 LNDFTTQRAKLQTE-NGELARQLEEKEALI---SQLTRGKLSYTQQMEDLKRQLE 1322
Score = 54.0 bits (124), Expect = 3e-06
Identities = 158/853 (18%), Positives = 346/853 (40%), Gaps = 83/853 (9%)
Query: 168 LDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSY 226
L E + E +E +A++ + +++K+R D ++ L+ + E A ++E +
Sbjct: 1110 LKENQARIEELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNK 1167
Query: 227 KKNTSFNK-----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAE 279
K+ F K EE + +E ++ + K ++ E+ID +R +Q +E K
Sbjct: 1168 KREAEFQKMRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEF 1226
Query: 280 IENITEVQTNEEAENATKTILEKVE-SLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQX 338
+ +V +N E K LEKV +L+ + + +E ++ F + T+
Sbjct: 1227 KLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTEN 1286
Query: 339 XXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQ 398
++ Q +A+N L Q
Sbjct: 1287 GELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEG--------KAKNAL-AHALQS 1337
Query: 399 EINEDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKH 455
++ + EQYE+E + EL + ++K + A+ + K + +T+E + +
Sbjct: 1338 ARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELE------EA 1391
Query: 456 KTALMELLGNVPEKDFAV-----TINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
K L + L + E AV ++ K + ++NE+ L+ ++++
Sbjct: 1392 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1451
Query: 511 RESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQD--EQNVLQSSMFIINKY 568
+ L E + + +++ ++ + Q +LS T + KL++ E+++ F
Sbjct: 1452 DKILAEWKQKYEESQSELESS---QKEARSLS---TELFKLKNAYEESLEHLETFKRENK 1505
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KD 624
Q + + G +N E + + LE+ L+ K +
Sbjct: 1506 NLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQL 1565
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMT-TAK 683
E +K+ E+ KD E+ Q ++ V ++T + ++ ++KM
Sbjct: 1566 EFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLN 1625
Query: 684 QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRV 743
++ + +R E + K +++ + D+++ LD A D K+ I+ + R
Sbjct: 1626 EMEIQLSHANRMAAEAQKQVKSLQSLLK-----DTQIQLDDAVRANDDLKENIAIVERRN 1680
Query: 744 KTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXX 799
Q +L ++ + A++EL+ T ++VQ + +L KK+++SD
Sbjct: 1681 NLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESD----- 1735
Query: 800 XXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQ 859
+T L+ ++E ++ + + I +A +A+ K + A ++
Sbjct: 1736 ---------LTQLQSEVEEAVQECRNAEEKAKKAI-TDAAMMAE---ELKKEQDTSAHLE 1782
Query: 860 QHKKKNVPREMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDN 918
+ KKN+ + ++ +Q D+ + K Q L ++ L+ E+ ++ KR+ +
Sbjct: 1783 R-MKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQ--KRNAESV 1839
Query: 919 LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELK 978
+RK++ I Q +E +K N + ++L +K L +K K ++AE A + L
Sbjct: 1840 KGMRKSERRIKELTYQTEE--DKKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLS 1896
Query: 979 KSLKGFRNELEKS 991
K K ++EL+++
Sbjct: 1897 KFRK-VQHELDEA 1908
Score = 53.2 bits (122), Expect = 5e-06
Identities = 137/732 (18%), Positives = 293/732 (40%), Gaps = 86/732 (11%)
Query: 385 KQAENELNIEECQQEINED-------EKAVEQYEQEMDELSQKI------TKLQKQTAKL 431
K EN+ IEE ++E+ + EK +E++E+S+++ T +Q + K
Sbjct: 1109 KLKENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKK 1168
Query: 432 KEKEM------IEENLKTKEKQLIVLKNKHKTALMELLGNVPE-KDFAVTINKFECEVRN 484
+E E +EE E L+ KH ++ EL + + + K + E +
Sbjct: 1169 REAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKL 1228
Query: 485 EVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKY 544
E+ LE + + + NE R +L +A+ +L+ +
Sbjct: 1229 ELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR-------------SLNDF 1275
Query: 545 TTTVEKLQDEQNVL-----QSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXX 599
TT KLQ E L + I +G+L R E E +
Sbjct: 1276 TTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHAL 1335
Query: 600 XXXMN----VPGKLEKVTE---DLQRASAK-KDEILSMKSLNEKITTLKDTEIPQLEKRI 651
+ + + E+ TE +LQR +K E+ ++ E + E+ + +K++
Sbjct: 1336 QSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKL 1395
Query: 652 VDVDTQIKTLNETVEEITMSLIEPEQ-KMTTAKQIHGDMPMLDRYIQEIKTVTKK---FE 707
+++ E VE + E+ K +I M ++R + KK F+
Sbjct: 1396 AQ---RLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFD 1452
Query: 708 AVKEQCGD--VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKT 765
+ + +S+ L+ + + ++ L+N + + + L ++ + L E+ +
Sbjct: 1453 KILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEIS 1512
Query: 766 KAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE-KI 820
E+L K V ++ LE K +LQS I ++ + K
Sbjct: 1513 DLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKA 1572
Query: 821 EAKTEVVRRNRDLIEAGSAY---IAKVEVAFNKVKSLDAEIQQHKKK--NVPREME-KIQ 874
E + ++ ++ ++ +A + + ++ + + E+ + KKK EME ++
Sbjct: 1573 EIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLS 1632
Query: 875 EANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL---DDNLCLRKAQTDITNW 931
AN E QKQ+ + + +L L D + + K ++ + L +A+ +
Sbjct: 1633 HANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRA 1692
Query: 932 QKQDDELNEKLNGINKEELNEKESLIIKQ-TKLFQQK----AECTGALSELKKSLKGFRN 986
+ E + KL E +E+ L+ Q T L QK ++ T SE++++++ RN
Sbjct: 1693 VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRN 1752
Query: 987 ELEKS---------LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKC---LMEFHRE 1034
EK+ ++++++K+ + + K +++ I++ LD+ ++ ++
Sbjct: 1753 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKK 1812
Query: 1035 KMENINMIIREL 1046
+++ + +REL
Sbjct: 1813 QLQKLEARVREL 1824
Score = 40.7 bits (91), Expect = 0.031
Identities = 66/360 (18%), Positives = 149/360 (41%), Gaps = 30/360 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKK 705
+ EK + + + + ET+E+ E E+KM + Q D+ +
Sbjct: 846 ETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDL---------------Q 890
Query: 706 FEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQK---KLNAHNKKLQTLYE 762
+ EQ D+E D ++ + K+ + R++ ++ +L A +KL+
Sbjct: 891 LQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECS 950
Query: 763 KKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEA 822
+ K ++L T KV+ + E+K + + +T + AL+E +
Sbjct: 951 ELKKDIDDLELTLAKVEKEKHATENKVK---NLTEEMAGLDEIIAKLTKEKKALQEAHQQ 1007
Query: 823 KTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQ-EANDKL- 880
+ ++ D + + S K+E +V L+ ++Q KK + E K + E + KL
Sbjct: 1008 ALDDLQVEEDKVNSLSKSKVKLE---QQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLT 1064
Query: 881 MEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE 940
E + D+ L +K+ + +I +Q + D+ + Q + Q + +EL E
Sbjct: 1065 QESIMDLENDKLQLEEKLKKKEFDINQQN--SKIEDEQALALQLQKKLKENQARIEELEE 1122
Query: 941 KLNG--INKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+L + ++ + S + ++ + ++ E G + ++ + R + + +D+E+
Sbjct: 1123 ELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1182
Score = 33.9 bits (74), Expect = 3.5
Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 6/162 (3%)
Query: 170 EGKKVKERFDEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKK 228
E K ++E + D D ++ L K + Q + LE K + +LE + +K
Sbjct: 997 EKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRK 1056
Query: 229 -NTSFNKEEEKIA---NEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENIT 284
+E I N+K E + K +Q KI+ ++ K + EN
Sbjct: 1057 LEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLK-ENQA 1115
Query: 285 EVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQG 326
++ EE A +T KVE L+SD + + E ++A G
Sbjct: 1116 RIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGG 1157
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 54.4 bits (125), Expect = 2e-06
Identities = 74/360 (20%), Positives = 151/360 (41%), Gaps = 25/360 (6%)
Query: 662 NETVEEITMSLIEPEQKMT--TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSE 719
N T SL E QK +Q+H +M + D Q+ +T K + + ++ + ++
Sbjct: 414 NRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQ 473
Query: 720 MTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ 779
+T Q++ K+K+ L++R+ Q+K N+K + + + + K++L + +K Q
Sbjct: 474 RRNLESTVSQIE-KEKM-LLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQ 531
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSA 839
+ E QLQ L + E ++ +++ NR+L E
Sbjct: 532 NSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQE---- 587
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKID 899
+ + N D + Q E E+ +D M Q L +++
Sbjct: 588 ---RNRILENSKSQTDKDYYQ---LQAILEAERRDRGHDSEMIGDLQARITS--LQEEVK 639
Query: 900 TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGIN---KEELNEKESL 956
LK + K E +++ D L ++ + N + +LN KL + ++E+NE +
Sbjct: 640 HLKHNLEKVEGERKEAQD--MLNHSEKEKNN---LEIDLNYKLKSLQQRLEQEVNEHKVT 694
Query: 957 IIKQTKLFQQKAECTG-ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+ T Q E A+ E++K LK R EK+ ++ ++ + + M ++ + ++ K
Sbjct: 695 KARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQK 754
Score = 52.8 bits (121), Expect = 7e-06
Identities = 132/642 (20%), Positives = 269/642 (41%), Gaps = 67/642 (10%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK- 452
E Q+ I + E+ + Q DE+ QK + K+ KE+ EE + + + V +
Sbjct: 426 ESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIM-KELDEEGNQRRNLESTVSQI 484
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLE-AERK--H 509
K K L + K A N+ V NEV + A K
Sbjct: 485 EKEKMLLQHRINEYQRK--AEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQ 542
Query: 510 IRESLNERRSEL-TKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKY 568
+++ L E L T+++ + ++S+ + +LQ+ +L++S +K
Sbjct: 543 LQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKD 602
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS 628
QL+ +RG ++E ++ +++ + +L++ ++ E
Sbjct: 603 YYQLQAILEAERRDRGHDSEM-----IGDLQARITSLQEEVKHLKHNLEKVEGERKEAQD 657
Query: 629 MKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE------ITMS-LIEPEQKMTT 681
M + +EK E LE +D++ ++K+L + +E+ +T + L + Q +
Sbjct: 658 MLNHSEK-------EKNNLE---IDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEE 707
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFE----AVKEQCGDVDSEMTLDVATAKQVDFKQKIS 737
AK + M +++ ++E + +K E +++QC +D ++ + + ++
Sbjct: 708 AKSVA--MCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKE-- 763
Query: 738 TLRNRVKTTQKKLNAH-NKKLQTLYEKKTKAKE--ELLNTQKKV-QDIVNLEESKKQLQS 793
+ + VK +L NK+L E KT+A E L +K++ Q+I L E+K+ L+
Sbjct: 764 RMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEF 823
Query: 794 DCXXXXXXXXXXXXAITPLEVALKEK----IEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
+ + L+ L+ + KT+V ++ E + K++ N
Sbjct: 824 ELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQN 883
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA-KQ 908
+ ++L ++ + K E E++ L+E+Q +T Q K + EI K
Sbjct: 884 EKETLATQLDLAETK---AESEQLARG---LLEEQYFELT--QESKKAASRNRQEITDKD 935
Query: 909 EVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ-- 966
R + N L K DI +++++EL EK+ +E EKE I F++
Sbjct: 936 HTVSRLEEANSMLTK---DIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNI 992
Query: 967 ------KAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
K + L+E+ + K F+ + +K+ ++D+ KK +E
Sbjct: 993 NTERTLKTQAVNKLAEI-MNRKDFKIDRKKANTQDLRKKEKE 1033
Score = 37.1 bits (82), Expect = 0.38
Identities = 42/163 (25%), Positives = 74/163 (45%), Gaps = 12/163 (7%)
Query: 170 EGKKVKERF-DEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKK 228
E KK R EI D D + RL++ +++++L + K K+ E+ YK
Sbjct: 919 ESKKAASRNRQEITDKDH---TVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKL 975
Query: 229 NTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQT 288
++EE+I+N K++ E N L++Q K+ + + + KI + T+
Sbjct: 976 -----EKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNR--KDFKIDRKKANTQDLR 1028
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDEC 331
+E EN + E K + V K Q + + +AQ V+EC
Sbjct: 1029 KKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQ-LVEEC 1070
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 54.4 bits (125), Expect = 2e-06
Identities = 135/683 (19%), Positives = 294/683 (43%), Gaps = 61/683 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+E+ ++ N +++ +++ E ++EL+ KI + +K+T +LK+K + L + ++ IV K
Sbjct: 310 MEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK 369
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
N+ + L N +K+ + E ++ E + E
Sbjct: 370 NQEIKNMKLELTNSKQKE------RQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 423
Query: 513 SLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTVEKLQ-----DEQNVLQS-SMFII 565
+R+ E +AE D++Y Q + ++ +E+++ + +N L+S S +
Sbjct: 424 QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITV 483
Query: 566 NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL-QRASAKKD 624
N+ + +L + + L N ++ + + L++ EDL + S ++
Sbjct: 484 NEDQIKLMNVAINEL-NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 542
Query: 625 EI-LSMKSLNEKITTLKD-----TEIPQLEKRIVDVDTQIKTL------NETVEEITMSL 672
+I + +++ E+ + L + + + L+ IV K L T +I + +
Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 602
Query: 673 IEPEQKMTTAKQIHGDMPMLDRY-IQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ-- 729
+E E+ + L+R Q + + ++ +KE D++ E +++ K
Sbjct: 603 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKE---DLEIEHRINIEKLKDNL 659
Query: 730 -VDFKQKISTLRN----RVKTTQ-KKLNAHNKKLQTLYE-KKTKAKEELLNTQKKVQDIV 782
+ +KQ+I L+N +++T Q +K N K+ Q + E K K ++ L K + +
Sbjct: 660 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 719
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
+ E +K+++ E+ LK ++ K ++ + DL E + A
Sbjct: 720 QINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEK-QMKEKENDLQEKFAQLEA 775
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPRE---MEKIQ-EANDKLMEKQKQIM-TDRQVLTKK 897
+ + ++ K+L+ ++ H + ++ I+ ++ D + EK+ +I+ + + L ++
Sbjct: 776 ENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQ 835
Query: 898 IDTLKDEIAKQEVYKRDLDDN--LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L +EI KQ + N + ++ Q + K D+L + NK+EL K
Sbjct: 836 CIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSK---NKQELEYKSK 892
Query: 956 LIIKQTKLFQQKAECTGALSELKKSL----KGFRNELEKSLSKDIEKKFREKMYELHVTK 1011
L +L Q+ T ++K S+ K F E + + +EK E M +L VTK
Sbjct: 893 LKALNEELHLQRINPTTV--KMKSSVFDEDKTFVAE-TLEMGEVVEKDTTELMEKLEVTK 949
Query: 1012 AIDKDIREYAVALDKCLMEFHRE 1034
++ + L + L + H E
Sbjct: 950 REKLELSQRLSDLSEQLKQKHGE 972
Score = 46.8 bits (106), Expect = 5e-04
Identities = 112/648 (17%), Positives = 266/648 (41%), Gaps = 71/648 (10%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDEL-SQKITKLQKQTAKLKEKEMIEENLK 442
HK ++ E +I + ++ E ++ +EQ E+DE+ Q+I +++++ + +M E +
Sbjct: 409 HKDSQFETDIVQRMEQ--ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 466
Query: 443 TKEKQLIVLKNKHKTALME---LLGNVPEKDFAVTI---NKFECEVRNEVXXXXXXXXXX 496
K + L++ + E L NV + + + N + +++ E+
Sbjct: 467 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 526
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQN 556
L E RE + R + + E K+ +A + L + + + E
Sbjct: 527 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE 586
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + K K ++ + + +R ES+ + +L K+ EDL
Sbjct: 587 LKHEAEVTNYKIKLEMLEKEKNAVLDR--MAESQEAELERLRTQLLFSHEEELSKLKEDL 644
Query: 617 Q---RASAKK----------DEILSMKS-LNEKITTL---KDTEIPQLEKRIVDV----D 655
+ R + +K +I +++ +++KI T+ KD I + + I+++ D
Sbjct: 645 EIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKD 704
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEA------- 708
Q +N EE+T+ + E ++++ +Q + L++ +QE++ T+ E
Sbjct: 705 LQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 764
Query: 709 -VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK--------TTQKKLNAHNKKLQT 759
++E+ +++E ++ K ++ KI T ++ + ++ K + K+++
Sbjct: 765 DLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEI 824
Query: 760 LYEKKTKAKEELLNTQKKVQD--------IVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
L E+ K++ + ++++ N E + ++LQ + +
Sbjct: 825 LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNK 884
Query: 812 LEVALKEKIEAKTE----------VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
E+ K K++A E V+ + + ++A+ + +V D
Sbjct: 885 QELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAET-LEMGEVVEKDTTELME 943
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
K + RE ++ + L E+ KQ + L +++ +LK E + + R+L+ +
Sbjct: 944 KLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINH 1003
Query: 922 RKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
+A+ N Q D +++ L+G+ E + K K F ++++
Sbjct: 1004 NRAE----NVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESK 1047
Score = 40.3 bits (90), Expect = 0.041
Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVY 911
+ L + QQ + R A D L KQ QI+T +Q L ++ L+D K+E
Sbjct: 236 QKLQIQFQQLQASETLRNSTHSSTAADLLQAKQ-QILTHQQQLEEQDHLLEDYQKKKE-- 292
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAEC 970
D + + Q I ++ + D+ K+ NKEE+ EKE++I + TK+ +++ +
Sbjct: 293 ----DFTMQISFLQEKIKVYEMEQDK---KVENSNKEEIQEKETIIEELNTKIIEEEKKT 345
Query: 971 TGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
ELK L L + + ++K K +L +T + K+
Sbjct: 346 L----ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE 387
Score = 34.3 bits (75), Expect = 2.7
Identities = 30/151 (19%), Positives = 76/151 (50%), Gaps = 7/151 (4%)
Query: 180 EIFDADKYSDCLDRLKKIRKDYAQNLK--LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
E+ + +K + LDR+ + ++ + L+ LL ++ + +++LE ++ N K+
Sbjct: 601 EMLEKEKNA-VLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNL 659
Query: 238 KIANEKSSNEIEYNKFILLESQNQEK---IDKRNEQIVETAKIAEIENITEVQTNEEAEN 294
I ++ + ++ +E+ EK I K+N+ I+E +K+ +++ +EE
Sbjct: 660 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 719
Query: 295 ATKTILEKVESLKSDHKVQKSQADEEEKKAQ 325
+ +++E L+ + K +K ++E ++ Q
Sbjct: 720 QINELQKEIEILRQEEK-EKGTLEQEVQELQ 749
>AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 792
Score = 54.4 bits (125), Expect = 2e-06
Identities = 92/405 (22%), Positives = 183/405 (45%), Gaps = 50/405 (12%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+L+ +T +LQ+ S++ +E+ K+T K+ E+ +L+K + + +T + N+ E+
Sbjct: 404 QLKILTMELQKKSSELEEMT-------KLTNNKEVELEELKKVLGEKETLLYE-NKQFEK 455
Query: 668 ITMSLIEPEQKM-----TTAKQIHGDMPMLDR-------YIQEIKTVTKKFEAVKEQCGD 715
I L EQ++ K++H L Y +E+K + K E E+ +
Sbjct: 456 IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL--KTELENEKLKN 513
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ 775
+ + + + + Q+ S + +K Q+ +N +NKK + E+ K E L T+
Sbjct: 514 TELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN-NNKKQE---ERMLKQIENLQETE 569
Query: 776 KKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIE 835
++++ LE +++L+ L ++ K + E+ + N+ L +
Sbjct: 570 TQLRN--ELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKK 627
Query: 836 AGSAYIAKVEVAFNKVKSLDAEIQQHKKK------NVPREME--KIQEAN-DKLMEKQKQ 886
G+A ++ V KV L+ E++ K+K +E+E KI E N + +EK K
Sbjct: 628 KGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENLLEEVEKAKV 687
Query: 887 IMTDRQVLTKKID-----TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD----- 936
I + L K+ID + + +A E +K D + R ++ + ++Q+
Sbjct: 688 IADEAVKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRA 747
Query: 937 ELNEKLNGINKEELNEKESLII---KQTKLFQQKAECTGALSELK 978
L +L+ + E L+ K+ L I ++ KL ++ E T L E K
Sbjct: 748 SLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKENTATLKEKK 792
Score = 39.9 bits (89), Expect = 0.054
Identities = 53/231 (22%), Positives = 106/231 (45%), Gaps = 20/231 (8%)
Query: 813 EVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVK-SLDAEIQQH----KKKNVP 867
+V+ + ++ K ++ NR +IEA I +++ KV L+ IQ++ K+ N
Sbjct: 120 KVSTEAELRQKESKLQENRKIIEAQRKAIQELQFGNEKVSLKLEEGIQENKDLIKENNAT 179
Query: 868 REM-EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
R + ++E + EK K+ +R+ + L + I K +L + ++
Sbjct: 180 RHLCNLLKETCARSAEKTKKYEYEREETRQVYMDLNNNIEKMITAFEEL--RVQAENSRL 237
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKES----LIIKQTKLFQQKAECTGALSELKKSLK 982
++ K+D E + L K+E+N+KE L+I+ T+ + + T L E + +
Sbjct: 238 EMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKV- 296
Query: 983 GFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIR---EYAVALDKCLME 1030
N+LE+ E + + H+TK ++ DI+ + +V+ K L E
Sbjct: 297 ---NQLEEKTKLQSENLKQSIEKQHHLTKELE-DIKVSLQRSVSTQKALEE 343
Score = 39.9 bits (89), Expect = 0.054
Identities = 32/108 (29%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Query: 211 YATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQ 270
Y+ VK + ELE+ KNT K++ E E + + LE +NQ++ D N +
Sbjct: 495 YSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSD-MTLELKNQQE-DINNNK 552
Query: 271 IVETAKIAEIENI--TEVQTNEEAENATKTILEKVESLKSDHKVQKSQ 316
E + +IEN+ TE Q E E + + +K + +K K+ KS+
Sbjct: 553 KQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKC--KLDKSE 598
>AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 54.4 bits (125), Expect = 2e-06
Identities = 119/663 (17%), Positives = 271/663 (40%), Gaps = 56/663 (8%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQE-----MDELSQKIT--KLQKQTAKLKEKEMI 437
+ E +L E+ + + E++ + E+ +++L +K+ K +K T + K +E +
Sbjct: 546 QNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEV 605
Query: 438 EENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKF-ECEVRNEVXXXXXXXXXX 496
+ Q + E+L E+ A+ + +C+ R E
Sbjct: 606 TQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICATKVE 665
Query: 497 XXXXXX-LEAERKHIRESLNERRSELTKAEDKIYKACGT-----QPYDVTLSKYTTTVEK 550
LE + I+ L + + EL K ++++ K Q + + K T ++
Sbjct: 666 TEEATACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQR 725
Query: 551 LQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP-GKL 609
+++ N++ IN+++ CN + S + VP
Sbjct: 726 IKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSS-LIINNKLICNETVEVPKDSK 784
Query: 610 EKVTEDLQRASA---KKDEILSMK-SLNEKITTLKDTE-IPQLEKRIVDVDTQIKTLNET 664
K+ + +R + ++DE + K S++ +D + ++ I +++ I+ L E
Sbjct: 785 SKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIE-DIRVLQEN 843
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDM-PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
E + L+ E ++ K+ ++ + + QE+ KK + ++ + S +
Sbjct: 844 NEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIA 903
Query: 724 VAT-----AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
+A +K + ++KI L N ++T + + + +++ ++ K + + +Q
Sbjct: 904 IAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISN 963
Query: 779 QDIVNL--------EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
D++NL E++ Q D E + + E +
Sbjct: 964 IDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEE 1023
Query: 831 -RDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT 889
+++++A S ++E +++ L AE++ +K +N + ++ + +D L EK+ I
Sbjct: 1024 CKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQ 1083
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
++ L +K TL +I Q V ++ L + +T ++ + EL E + K E
Sbjct: 1084 LKEELQEKNVTLDVQI--QHV----VEGKRALSELTQGVTCYKAKIKEL-ETILETQKVE 1136
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL--SKDI---EKKFREKM 1004
+ KL Q E + +L+++LK F+ L+ S+ +KD+ E K +E++
Sbjct: 1137 CSH-------SAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEI 1189
Query: 1005 YEL 1007
+L
Sbjct: 1190 TQL 1192
Score = 51.2 bits (117), Expect = 2e-05
Identities = 91/431 (21%), Positives = 185/431 (42%), Gaps = 36/431 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++E++ + +++ A E+ K N + LK+ E + + + +T I+ L E ++E
Sbjct: 1037 QIEELEQQIEKLQA---EVKGYKDENNR---LKEKEHKNQDDLLKEKETLIQQLKEELQE 1090
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++L Q + K+ ++ + Y +IK + E K +C +++ D+
Sbjct: 1091 KNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSH-SAKLEQDILE 1149
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL-- 784
+ + K L +K Q+ L K + L K+ K KEE+ +QD+ +L
Sbjct: 1150 KESIILK-----LERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQ 1204
Query: 785 --EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE ++ + + L+ L+ K E ++ + D +
Sbjct: 1205 LKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQK 1264
Query: 843 KVEVAFNKVKSLDAEIQQ-HKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+V V ++ K L +I + KKKN +E++ Q +L E+ + + + +
Sbjct: 1265 EVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVE-EAIQQYERA 1323
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--EELNE-KESLI 957
KD K+++ + D+ L + QT + +QD L KL + + EL + KE
Sbjct: 1324 CKDLNVKEKIIE-DMRMTL-EEQEQTQV----EQDQVLEAKLEEVERLATELEKWKEKCN 1377
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK---DIEKKFREKMYELHVTKAID 1014
+TK Q+ + +++ L ++EL++S K D +K EKM + K +
Sbjct: 1378 DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAE 1437
Query: 1015 ----KDIREYA 1021
K++++YA
Sbjct: 1438 NIRNKEMKKYA 1448
Score = 50.4 bits (115), Expect = 4e-05
Identities = 119/655 (18%), Positives = 257/655 (39%), Gaps = 30/655 (4%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIV 450
+N E QQ+ +K + E +K +++ A++++ +++EN + L+
Sbjct: 794 VNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLT 853
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
++N+ K E E + + + E + + + H+
Sbjct: 854 IENELKNEKEEKA----ELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHV 909
Query: 511 RESLNERRSE-LTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++S N+ + E + K ++I A + +V+ K T K+ DE L S I N
Sbjct: 910 QKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHT--KI-DELRTLDSVSQISNIDL 966
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
L+D L N E+ ++ K ++ E + S
Sbjct: 967 LNLRD-----LSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIW 1021
Query: 630 KSLNE--KITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG 687
+ E K ++ K +I +LE++I + ++K + E + E + + K+
Sbjct: 1022 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKD--ENNRLKEKEHKNQDDLLKEKET 1079
Query: 688 DMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQ 747
+ L +QE K VT + V+ + L T +K KI L + TQ
Sbjct: 1080 LIQQLKEELQE-KNVTLDVQIQHV----VEGKRALSELTQGVTCYKAKIKELET-ILETQ 1133
Query: 748 KKLNAHNKKL-QTLYEKKT---KAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXX 803
K +H+ KL Q + EK++ K + L Q+ +QD V + +
Sbjct: 1134 KVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLT 1193
Query: 804 XXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK 863
+ L +E+ E + + ++ + A SA ++ + + A++++ K
Sbjct: 1194 NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE-KL 1252
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
+ ++++++Q+ + ++ K + L KK + E+ ++ + L + L +K
Sbjct: 1253 TDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQK 1312
Query: 924 AQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ I +++ +LN EK+ + L E+E ++Q ++ + K E L+ +
Sbjct: 1313 VEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKW 1372
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM 1036
K N+LE ++ K+ L + +++E + ++ EKM
Sbjct: 1373 KEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKM 1427
>AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 54.4 bits (125), Expect = 2e-06
Identities = 119/663 (17%), Positives = 271/663 (40%), Gaps = 56/663 (8%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQE-----MDELSQKIT--KLQKQTAKLKEKEMI 437
+ E +L E+ + + E++ + E+ +++L +K+ K +K T + K +E +
Sbjct: 546 QNVETKLLDEDLDKTLEENKAFISHEEKRKLLDLIEDLKKKLINEKKEKLTLEFKIREEV 605
Query: 438 EENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKF-ECEVRNEVXXXXXXXXXX 496
+ Q + E+L E+ A+ + +C+ R E
Sbjct: 606 TQEFTQYWAQREADFKETLLQEREILEENAERRLAIFKDLVGKCDTREEAAKDICATKVE 665
Query: 497 XXXXXX-LEAERKHIRESLNERRSELTKAEDKIYKACGT-----QPYDVTLSKYTTTVEK 550
LE + I+ L + + EL K ++++ K Q + + K T ++
Sbjct: 666 TEEATACLELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSNKKIITQNQR 725
Query: 551 LQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP-GKL 609
+++ N++ IN+++ CN + S + VP
Sbjct: 726 IKELINIIDQKEDTINEFQNLKSHMENTFKCNDKADTSS-LIINNKLICNETVEVPKDSK 784
Query: 610 EKVTEDLQRASA---KKDEILSMK-SLNEKITTLKDTE-IPQLEKRIVDVDTQIKTLNET 664
K+ + +R + ++DE + K S++ +D + ++ I +++ I+ L E
Sbjct: 785 SKICSERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIE-DIRVLQEN 843
Query: 665 VEEITMSLIEPEQKMTTAKQIHGDM-PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLD 723
E + L+ E ++ K+ ++ + + QE+ KK + ++ + S +
Sbjct: 844 NEGLRAFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIA 903
Query: 724 VAT-----AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
+A +K + ++KI L N ++T + + + +++ ++ K + + +Q
Sbjct: 904 IAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISN 963
Query: 779 QDIVNL--------EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
D++NL E++ Q D E + + E +
Sbjct: 964 IDLLNLRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEE 1023
Query: 831 -RDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT 889
+++++A S ++E +++ L AE++ +K +N + ++ + +D L EK+ I
Sbjct: 1024 CKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQ 1083
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
++ L +K TL +I Q V ++ L + +T ++ + EL E + K E
Sbjct: 1084 LKEELQEKNVTLDVQI--QHV----VEGKRALSELTQGVTCYKAKIKEL-ETILETQKVE 1136
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSL--SKDI---EKKFREKM 1004
+ KL Q E + +L+++LK F+ L+ S+ +KD+ E K +E++
Sbjct: 1137 CSH-------SAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEI 1189
Query: 1005 YEL 1007
+L
Sbjct: 1190 TQL 1192
Score = 51.2 bits (117), Expect = 2e-05
Identities = 91/431 (21%), Positives = 185/431 (42%), Gaps = 36/431 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++E++ + +++ A E+ K N + LK+ E + + + +T I+ L E ++E
Sbjct: 1037 QIEELEQQIEKLQA---EVKGYKDENNR---LKEKEHKNQDDLLKEKETLIQQLKEELQE 1090
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++L Q + K+ ++ + Y +IK + E K +C +++ D+
Sbjct: 1091 KNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVECSH-SAKLEQDILE 1149
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL-- 784
+ + K L +K Q+ L K + L K+ K KEE+ +QD+ +L
Sbjct: 1150 KESIILK-----LERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQ 1204
Query: 785 --EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE ++ + + L+ L+ K E ++ + D +
Sbjct: 1205 LKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQK 1264
Query: 843 KVEVAFNKVKSLDAEIQQ-HKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+V V ++ K L +I + KKKN +E++ Q +L E+ + + + +
Sbjct: 1265 EVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVE-EAIQQYERA 1323
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--EELNE-KESLI 957
KD K+++ + D+ L + QT + +QD L KL + + EL + KE
Sbjct: 1324 CKDLNVKEKIIE-DMRMTL-EEQEQTQV----EQDQVLEAKLEEVERLATELEKWKEKCN 1377
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK---DIEKKFREKMYELHVTKAID 1014
+TK Q+ + +++ L ++EL++S K D +K EKM + K +
Sbjct: 1378 DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAE 1437
Query: 1015 ----KDIREYA 1021
K++++YA
Sbjct: 1438 NIRNKEMKKYA 1448
Score = 50.4 bits (115), Expect = 4e-05
Identities = 119/655 (18%), Positives = 257/655 (39%), Gaps = 30/655 (4%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIV 450
+N E QQ+ +K + E +K +++ A++++ +++EN + L+
Sbjct: 794 VNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLT 853
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
++N+ K E E + + + E + + + H+
Sbjct: 854 IENELKNEKEEKA----ELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHV 909
Query: 511 RESLNERRSE-LTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++S N+ + E + K ++I A + +V+ K T K+ DE L S I N
Sbjct: 910 QKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHT--KI-DELRTLDSVSQISNIDL 966
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
L+D L N E+ ++ K ++ E + S
Sbjct: 967 LNLRD-----LSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIW 1021
Query: 630 KSLNE--KITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG 687
+ E K ++ K +I +LE++I + ++K + E + E + + K+
Sbjct: 1022 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKD--ENNRLKEKEHKNQDDLLKEKET 1079
Query: 688 DMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQ 747
+ L +QE K VT + V+ + L T +K KI L + TQ
Sbjct: 1080 LIQQLKEELQE-KNVTLDVQIQHV----VEGKRALSELTQGVTCYKAKIKELET-ILETQ 1133
Query: 748 KKLNAHNKKL-QTLYEKKT---KAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXX 803
K +H+ KL Q + EK++ K + L Q+ +QD V + +
Sbjct: 1134 KVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLT 1193
Query: 804 XXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK 863
+ L +E+ E + + ++ + A SA ++ + + A++++ K
Sbjct: 1194 NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE-KL 1252
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
+ ++++++Q+ + ++ K + L KK + E+ ++ + L + L +K
Sbjct: 1253 TDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQK 1312
Query: 924 AQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ I +++ +LN EK+ + L E+E ++Q ++ + K E L+ +
Sbjct: 1313 VEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKW 1372
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM 1036
K N+LE ++ K+ L + +++E + ++ EKM
Sbjct: 1373 KEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKM 1427
>AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.
Length = 1620
Score = 54.4 bits (125), Expect = 2e-06
Identities = 135/683 (19%), Positives = 294/683 (43%), Gaps = 61/683 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+E+ ++ N +++ +++ E ++EL+ KI + +K+T +LK+K + L + ++ IV K
Sbjct: 291 MEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK 350
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
N+ + L N +K+ + E ++ E + E
Sbjct: 351 NQEIKNMKLELTNSKQKE------RQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 404
Query: 513 SLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTVEKLQ-----DEQNVLQS-SMFII 565
+R+ E +AE D++Y Q + ++ +E+++ + +N L+S S +
Sbjct: 405 QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITV 464
Query: 566 NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL-QRASAKKD 624
N+ + +L + + L N ++ + + L++ EDL + S ++
Sbjct: 465 NEDQIKLMNVAINEL-NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 523
Query: 625 EI-LSMKSLNEKITTLKD-----TEIPQLEKRIVDVDTQIKTL------NETVEEITMSL 672
+I + +++ E+ + L + + + L+ IV K L T +I + +
Sbjct: 524 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 583
Query: 673 IEPEQKMTTAKQIHGDMPMLDRY-IQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ-- 729
+E E+ + L+R Q + + ++ +KE D++ E +++ K
Sbjct: 584 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKE---DLEIEHRINIEKLKDNL 640
Query: 730 -VDFKQKISTLRN----RVKTTQ-KKLNAHNKKLQTLYE-KKTKAKEELLNTQKKVQDIV 782
+ +KQ+I L+N +++T Q +K N K+ Q + E K K ++ L K + +
Sbjct: 641 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 700
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
+ E +K+++ E+ LK ++ K ++ + DL E + A
Sbjct: 701 QINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEK-QMKEKENDLQEKFAQLEA 756
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPRE---MEKIQ-EANDKLMEKQKQIM-TDRQVLTKK 897
+ + ++ K+L+ ++ H + ++ I+ ++ D + EK+ +I+ + + L ++
Sbjct: 757 ENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQ 816
Query: 898 IDTLKDEIAKQEVYKRDLDDN--LCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L +EI KQ + N + ++ Q + K D+L + NK+EL K
Sbjct: 817 CIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSK---NKQELEYKSK 873
Query: 956 LIIKQTKLFQQKAECTGALSELKKSL----KGFRNELEKSLSKDIEKKFREKMYELHVTK 1011
L +L Q+ T ++K S+ K F E + + +EK E M +L VTK
Sbjct: 874 LKALNEELHLQRINPTTV--KMKSSVFDEDKTFVAE-TLEMGEVVEKDTTELMEKLEVTK 930
Query: 1012 AIDKDIREYAVALDKCLMEFHRE 1034
++ + L + L + H E
Sbjct: 931 REKLELSQRLSDLSEQLKQKHGE 953
Score = 46.8 bits (106), Expect = 5e-04
Identities = 112/648 (17%), Positives = 266/648 (41%), Gaps = 71/648 (10%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDEL-SQKITKLQKQTAKLKEKEMIEENLK 442
HK ++ E +I + ++ E ++ +EQ E+DE+ Q+I +++++ + +M E +
Sbjct: 390 HKDSQFETDIVQRMEQ--ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 447
Query: 443 TKEKQLIVLKNKHKTALME---LLGNVPEKDFAVTI---NKFECEVRNEVXXXXXXXXXX 496
K + L++ + E L NV + + + N + +++ E+
Sbjct: 448 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 507
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQN 556
L E RE + R + + E K+ +A + L + + + E
Sbjct: 508 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE 567
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + K K ++ + + +R ES+ + +L K+ EDL
Sbjct: 568 LKHEAEVTNYKIKLEMLEKEKNAVLDR--MAESQEAELERLRTQLLFSHEEELSKLKEDL 625
Query: 617 Q---RASAKK----------DEILSMKS-LNEKITTL---KDTEIPQLEKRIVDV----D 655
+ R + +K +I +++ +++KI T+ KD I + + I+++ D
Sbjct: 626 EIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKD 685
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEA------- 708
Q +N EE+T+ + E ++++ +Q + L++ +QE++ T+ E
Sbjct: 686 LQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 745
Query: 709 -VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVK--------TTQKKLNAHNKKLQT 759
++E+ +++E ++ K ++ KI T ++ + ++ K + K+++
Sbjct: 746 DLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEI 805
Query: 760 LYEKKTKAKEELLNTQKKVQD--------IVNLEESKKQLQSDCXXXXXXXXXXXXAITP 811
L E+ K++ + ++++ N E + ++LQ + +
Sbjct: 806 LIEENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNK 865
Query: 812 LEVALKEKIEAKTE----------VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQH 861
E+ K K++A E V+ + + ++A+ + +V D
Sbjct: 866 QELEYKSKLKALNEELHLQRINPTTVKMKSSVFDEDKTFVAET-LEMGEVVEKDTTELME 924
Query: 862 KKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
K + RE ++ + L E+ KQ + L +++ +LK E + + R+L+ +
Sbjct: 925 KLEVTKREKLELSQRLSDLSEQLKQKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINH 984
Query: 922 RKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAE 969
+A+ N Q D +++ L+G+ E + K K F ++++
Sbjct: 985 NRAE----NVQSCDTQVSSLLDGVVTMTSRGAEGSVSKVNKSFGEESK 1028
Score = 40.3 bits (90), Expect = 0.041
Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVY 911
+ L + QQ + R A D L KQ QI+T +Q L ++ L+D K+E
Sbjct: 217 QKLQIQFQQLQASETLRNSTHSSTAADLLQAKQ-QILTHQQQLEEQDHLLEDYQKKKE-- 273
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAEC 970
D + + Q I ++ + D+ K+ NKEE+ EKE++I + TK+ +++ +
Sbjct: 274 ----DFTMQISFLQEKIKVYEMEQDK---KVENSNKEEIQEKETIIEELNTKIIEEEKKT 326
Query: 971 TGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
ELK L L + + ++K K +L +T + K+
Sbjct: 327 L----ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE 368
Score = 34.3 bits (75), Expect = 2.7
Identities = 30/151 (19%), Positives = 76/151 (50%), Gaps = 7/151 (4%)
Query: 180 EIFDADKYSDCLDRLKKIRKDYAQNLK--LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
E+ + +K + LDR+ + ++ + L+ LL ++ + +++LE ++ N K+
Sbjct: 582 EMLEKEKNA-VLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNL 640
Query: 238 KIANEKSSNEIEYNKFILLESQNQEK---IDKRNEQIVETAKIAEIENITEVQTNEEAEN 294
I ++ + ++ +E+ EK I K+N+ I+E +K+ +++ +EE
Sbjct: 641 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 700
Query: 295 ATKTILEKVESLKSDHKVQKSQADEEEKKAQ 325
+ +++E L+ + K +K ++E ++ Q
Sbjct: 701 QINELQKEIEILRQEEK-EKGTLEQEVQELQ 730
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-coil
containing protein kinase 1 variant protein.
Length = 705
Score = 54.4 bits (125), Expect = 2e-06
Identities = 74/360 (20%), Positives = 151/360 (41%), Gaps = 25/360 (6%)
Query: 662 NETVEEITMSLIEPEQKMT--TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSE 719
N T SL E QK +Q+H +M + D Q+ +T K + + ++ + ++
Sbjct: 92 NRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQ 151
Query: 720 MTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ 779
+T Q++ K+K+ L++R+ Q+K N+K + + + + K++L + +K Q
Sbjct: 152 RRNLESTVSQIE-KEKM-LLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQ 209
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSA 839
+ E QLQ L + E ++ +++ NR+L E
Sbjct: 210 NSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQE---- 265
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKID 899
+ + N D + Q E E+ +D M Q L +++
Sbjct: 266 ---RNRILENSKSQTDKDYYQ---LQAILEAERRDRGHDSEMIGDLQARITS--LQEEVK 317
Query: 900 TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGIN---KEELNEKESL 956
LK + K E +++ D L ++ + N + +LN KL + ++E+NE +
Sbjct: 318 HLKHNLEKVEGERKEAQD--MLNHSEKEKNN---LEIDLNYKLKSLQQRLEQEVNEHKVT 372
Query: 957 IIKQTKLFQQKAECTG-ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+ T Q E A+ E++K LK R EK+ ++ ++ + + M ++ + ++ K
Sbjct: 373 KARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQK 432
Score = 47.2 bits (107), Expect = 4e-04
Identities = 129/636 (20%), Positives = 265/636 (41%), Gaps = 67/636 (10%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK- 452
E Q+ I + E+ + Q DE+ QK + K+ KE+ EE + + + V +
Sbjct: 104 ESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIM-KELDEEGNQRRNLESTVSQI 162
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLE-AERK--H 509
K K L + K A N+ V NEV + A K
Sbjct: 163 EKEKMLLQHRINEYQRK--AEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQ 220
Query: 510 IRESLNERRSEL-TKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKY 568
+++ L E L T+++ + ++S+ + +LQ+ +L++S +K
Sbjct: 221 LQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKD 280
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS 628
QL+ +RG ++E ++ +++ + +L++ ++ E
Sbjct: 281 YYQLQAILEAERRDRGHDSEM-----IGDLQARITSLQEEVKHLKHNLEKVEGERKEAQD 335
Query: 629 MKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE------ITMS-LIEPEQKMTT 681
M + +EK E LE +D++ ++K+L + +E+ +T + L + Q +
Sbjct: 336 MLNHSEK-------EKNNLE---IDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEE 385
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFE----AVKEQCGDVDSEMTLDVATAKQVDFKQKIS 737
AK + M +++ ++E + +K E +++QC +D ++ + + ++
Sbjct: 386 AKSVA--MCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKE-- 441
Query: 738 TLRNRVKTTQKKLNAH-NKKLQTLYEKKTKAKE--ELLNTQKKV-QDIVNLEESKKQLQS 793
+ + VK +L NK+L E KT+A E L +K++ Q+I L E+K+ L+
Sbjct: 442 RMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEF 501
Query: 794 DCXXXXXXXXXXXXAITPLEVALKEK----IEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
+ + L+ L+ + KT+V ++ E + K++ N
Sbjct: 502 ELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQN 561
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA-KQ 908
+ ++L ++ + K E E++ L+E+Q +T Q K + EI K
Sbjct: 562 EKETLATQLDLAETK---AESEQLARG---LLEEQYFELT--QESKKAASRNRQEITDKD 613
Query: 909 EVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ-- 966
R + N L K DI +++++EL EK+ +E EKE I F++
Sbjct: 614 HTVSRLEEANSMLTK---DIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNI 670
Query: 967 ------KAECTGALSELKKSLKGFRNELEKSLSKDI 996
K + L+E+ + K F+ + +K+ ++D+
Sbjct: 671 NTERTLKTQAVNKLAEI-MNRKDFKIDRKKANTQDL 705
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 54.0 bits (124), Expect = 3e-06
Identities = 120/622 (19%), Positives = 259/622 (41%), Gaps = 52/622 (8%)
Query: 411 EQEMDELSQKITKLQKQTAKLKEKEM-IEENLKTKEKQLIVLKNKHKTALMELLGNVPEK 469
++E+ +L + I KL+ + ++K++ I E LK ++ + LK+K + EL + +
Sbjct: 14 QEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQMSEENQ 73
Query: 470 DFAVTI---NKFECE-VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAE 525
+ + +K E E ++ ++ L +E++++ + + E++ +L++
Sbjct: 74 ELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSEL- 132
Query: 526 DKIYKACGTQ-----PYDVTLSKYT-TTVEKLQDEQNVLQSSMFIINKYKGQLK--DNSC 577
DK+ + +Q ++ + + + T VE LQ++ L ++ + + +K + S
Sbjct: 133 DKLLSSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSL 192
Query: 578 CPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKIT 637
P + + L+++ E A K + +++ E
Sbjct: 193 DPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIAR 252
Query: 638 TLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQ 697
T ++ + E +++TL +E +T SL E + T + D L +Q
Sbjct: 253 TNQEHAALEAENS----KGEVETLKAKIEGMTQSLRGLELDVVTIRSEKED---LTNELQ 305
Query: 698 EIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKL 757
+ + + E + ++ L ++V K+K ST ++T Q K + +
Sbjct: 306 KEQERISELEIINSSFENI-----LQEKEQEKVQMKEKSSTAMEMLQT-QLKSSMREWQP 359
Query: 758 QTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVAL- 816
+ +K AKE+ L++Q + LE K QL ++ L +
Sbjct: 360 CIMTKKPVSAKEQNLSSQVEC-----LELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVE 414
Query: 817 --KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP-REME-K 872
K+K+E K E + R ++ I+ E +K+ ++ E Q K++N+ R + +
Sbjct: 415 DGKQKLEKKDEEISRLKNQIQ-------DQEQLVSKLSQVEGEHQLWKEQNLELRNLTVE 467
Query: 873 IQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKA-----QTD 927
+++ L K + +VL L++E+ ++ K + + A Q +
Sbjct: 468 LEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQRE 527
Query: 928 ITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ-QKAECTGALSELKKSLKGFRN 986
+ ++ EL E+L+G K L + L++++ K + Q E T SELKKSL
Sbjct: 528 MHEMAQKTAELQEELSG-EKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHK 586
Query: 987 ELEKSLSKDIEKKFREKMYELH 1008
+ + K + ++ E LH
Sbjct: 587 DQVEKEGK-VREEIAEYQLRLH 607
Score = 51.2 bits (117), Expect = 2e-05
Identities = 139/764 (18%), Positives = 315/764 (41%), Gaps = 89/764 (11%)
Query: 181 IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIA 240
I DA+ ++ LK ++ A++LK+ E T++++++ L ++ E +K+
Sbjct: 77 ILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLL 136
Query: 241 NE-KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK-IAEIENITEVQTNEEAENATKT 298
+ KS E + I ++ +++ ++ Q+ E + +A + E+ + E +
Sbjct: 137 SSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIM--KATEQSLDP 194
Query: 299 ILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXX 358
+E+ L++ + +++ + +EKK + + +
Sbjct: 195 PIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL------ 248
Query: 359 DITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELS 418
+I NQ K IE Q + E V E ++L+
Sbjct: 249 EIARTNQEHAALEAENSKGEVETLKAK-------IEGMTQSLRGLELDVVTIRSEKEDLT 301
Query: 419 QKITKLQKQTAKLKEKEMIEEN-LKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINK 477
++ K Q++ ++L+ EN L+ KE++ + +K K TA ME+L + ++ +
Sbjct: 302 NELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTA-MEML----QTQLKSSMRE 356
Query: 478 FECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPY 537
++ + + LE E+ + + L+E ++ Y
Sbjct: 357 WQPCIMTK-KPVSAKEQNLSSQVECLELEKAQLLQGLDEAKNN----------------Y 399
Query: 538 DVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXX 597
V S +++++D + L+ I++ K Q++D L ++ + E E
Sbjct: 400 IVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQE--QLVSKLSQVEGEHQLWKEQ 457
Query: 598 XXXXXMNVPGKLEKVTEDLQRASAKKDEIL-----SMKSLNEKITTLKDTEIPQLEKRIV 652
N+ +LE+ + LQ +A + L S K+L ++ K ++ +EK +
Sbjct: 458 NLELR-NLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK-VN 515
Query: 653 DVDTQIKTLNETVEEITMSLIEPEQKMTTAK-QIHGDMPMLDRYIQEIKTVTKKFEAVKE 711
+ + L + E+ E +++++ K ++ G++ +L ++EIK+ + + +
Sbjct: 516 KMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLL---LEEIKSSKDQLKELTL 572
Query: 712 QCGDVDSEMTLDVATAKQVD----FKQKISTLRNRVKTTQKKLNA----HNKKLQT---L 760
+ ++ + +LD QV+ +++I+ + R+ +KK A NK+ +
Sbjct: 573 ENSEL--KKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQT 630
Query: 761 YEKKTKAKEELLNTQKKVQDIVN----------------LEESKKQLQSDCXXXXXXXXX 804
Y +K +KEE L++QK D++ LEE KK +
Sbjct: 631 YREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKE 690
Query: 805 XXXAITPLEVALK--EKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHK 862
A +++ +K +++E + E++++ ++A V KV L EI++ K
Sbjct: 691 NERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELK 750
Query: 863 KKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
+ EK +EA D+ ++K ++ + L K + L+ ++A
Sbjct: 751 E----TLEEKTKEA-DEYLDKYCSLLISHEKLEKAKEMLETQVA 789
Score = 39.5 bits (88), Expect = 0.071
Identities = 38/167 (22%), Positives = 77/167 (46%), Gaps = 4/167 (2%)
Query: 860 QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA--KQEVYKRDLDD 917
Q + + R +EK++ + +KQ I + + D+LKD++ ++E+ + +
Sbjct: 14 QEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERDGENDSLKDKVENLERELQMSEENQ 73
Query: 918 NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSEL 977
L + A+ + ++ E + EL + +L ++ L +Q E G LSEL
Sbjct: 74 ELVILDAENSKAEVETLKTQIEEMARSLKVFEL-DLVTLRSEKENLTKQIQEKQGQLSEL 132
Query: 978 KKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVAL 1024
K L F+++LE+ +I+ K E + + + K++ E AL
Sbjct: 133 DKLLSSFKSQLEEKEQAEIQIK-EESKTAVEMLQNQLKELNEAVAAL 178
Score = 35.9 bits (79), Expect = 0.88
Identities = 65/355 (18%), Positives = 158/355 (44%), Gaps = 43/355 (12%)
Query: 697 QEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL--NAHN 754
+E+ + + E ++ + + D + L +A K + + +L+++V+ +++L + N
Sbjct: 15 EEVHQLRRGIEKLRVRI-EADEKKQLHIAE-KLKERDGENDSLKDKVENLERELQMSEEN 72
Query: 755 KKLQTLYEKKTKAKEELLNTQKKVQ---------DIVNLEESKKQLQSDCXXXXXXXXXX 805
++L L + +KA+ E L TQ + D+V L K+ L
Sbjct: 73 QELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSEL 132
Query: 806 XXAITPLEVALKEKIEAKTEVVRRN-----------RDLIEAGSAYIAKVEVAFNKVKSL 854
++ + L+EK +A+ ++ + ++L EA +A E+ +SL
Sbjct: 133 DKLLSSFKSQLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSL 192
Query: 855 DAEI-QQHKKKNVPREMEKIQEANDK----LMEKQKQIMTDRQVLTKKIDTLKDEIAKQE 909
D I ++H+ +N ++ EA++K ++++ K+ +L +++ L+ E+ E
Sbjct: 193 DPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL---E 249
Query: 910 VYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEEL---NEKESLIIKQTKLFQ 965
+ + + + L ++ ++ + + + + + L G+ + + +EKE L T Q
Sbjct: 250 IARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDL----TNELQ 305
Query: 966 QKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREY 1020
++ E +SEL+ F N L++ + ++ K + + + +RE+
Sbjct: 306 KEQE---RISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKSSMREW 357
>BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein.
Length = 863
Score = 54.0 bits (124), Expect = 3e-06
Identities = 100/507 (19%), Positives = 210/507 (41%), Gaps = 45/507 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK--EMIEENLKTKEKQLIV 450
+++ EIN+ + E+ +Q+M + + + ++ K++E+ + EN K++ V
Sbjct: 334 LDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEV 393
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVR-NEVXXXXXXXXXXXXXXXXLEAERKH 509
L+ AL EL N +K + E + R NE + E
Sbjct: 394 LQ-----ALEELAVNYDQKS-----QEVEDKTRANE--QLTDELAQKTTTLTTTQRELSQ 441
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++E N ++ T+ + + K G ++ T V+ L D V++ + Y
Sbjct: 442 LQELSNHQKKRATEILNLLLKDLG----EIGGIIGTNDVKTLADVNGVIEEEFTMARLYI 497
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNV----------PGKLEKVTEDLQRA 619
++K + L NR + ES + K++ +T+ +Q
Sbjct: 498 SKMK-SEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 556
Query: 620 SAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
K+ ++ S SL+E++ L+ E E D + + T + EE+ +L EQ+
Sbjct: 557 EQKRRQLEESQDSLSEELAKLRAQE-KMHEVSFQDKEKEHLTRLQDAEEMKKAL---EQQ 612
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE--QCGDVDSEMTLDVATAKQVDFKQKI 736
M + ++ H L R EI+ K + +++ Q ++ E +++ +++
Sbjct: 613 MESHREAH--QKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQERE 670
Query: 737 STLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK-VQDIVNLEESKKQLQSDC 795
L + K+ A + L+ L E ++ + L N +K VQD+ + +L +D
Sbjct: 671 MKLEKLLLLNDKREQA-REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDND- 728
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
I+ LE L++ + ++VR N DL ++ +VK+L+
Sbjct: 729 --DGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALE 786
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLME 882
+ +++ K+N R+ ++ Q+ D++ E
Sbjct: 787 SALKE-AKENAMRDRKRYQQEVDRIKE 812
Score = 38.7 bits (86), Expect = 0.12
Identities = 83/429 (19%), Positives = 179/429 (41%), Gaps = 41/429 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+N K ++V ED RA+ + + L+ K+ T + +++ +L T+I LN
Sbjct: 402 VNYDQKSQEV-EDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEI--LN 458
Query: 663 ETVEEI-TMSLIEPEQKMTTAKQIHG----DMPMLDRYIQEIKTVTKKFEAVKEQC--GD 715
++++ + I + T ++G + M YI ++K+ K +Q
Sbjct: 459 LLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQ 518
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL--LN 773
+DS ++ + + + IS ++K+ + +K + L E + EEL L
Sbjct: 519 MDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLR 578
Query: 774 TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEV------ALKEKIEAKTEVV 827
Q+K+ ++ ++ K+ L + E L+++IE K +++
Sbjct: 579 AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKII 638
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQI 887
RDL + K+ +NK+K D E + ++EK+ NDK + ++ +
Sbjct: 639 DEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREM--------KLEKLLLLNDKREQAREDL 690
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL-NEKLNGIN 946
+ +++++ TL + ++++ +DL + K ++ N +K++ +
Sbjct: 691 KGLEETVSRELQTLHN---LRKLFVQDLTTRV---KKSVELDNDDGGGSAAQKQKISFLE 744
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNE---LEKSLSKDIEKKFRE- 1002
N E L +L + A+ L +L+K L+ LE +L + E R+
Sbjct: 745 ----NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDR 800
Query: 1003 KMYELHVTK 1011
K Y+ V +
Sbjct: 801 KRYQQEVDR 809
Score = 37.5 bits (83), Expect = 0.29
Identities = 77/415 (18%), Positives = 166/415 (40%), Gaps = 22/415 (5%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
E +N ++ QE+ + +A EQ DEL+QK T L +L + + + + K + +
Sbjct: 399 ELAVNYDQKSQEVEDKTRANEQLT---DELAQKTTTLTTTQRELSQLQELSNHQKKRATE 455
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
++ L K L E+ G + D T+ + E L
Sbjct: 456 ILNLLLKD---LGEIGGIIGTND-VKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRS 511
Query: 508 KHIRESLNERRSELTKAEDKIYKACG--TQPYDVTLSKYTTTVEKLQDEQNVLQSSMFII 565
K + + + ++ +E ++ AC ++ + T ++ ++ ++ L+ S +
Sbjct: 512 KQLESAQMDSNRKMNASEREL-AACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSL 570
Query: 566 NKYKGQLKDNSCCPLCNRGFEN-ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR-ASAKK 623
++ +L+ + F++ E E + ++E E Q+ S +
Sbjct: 571 SEELAKLRAQE--KMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLR 628
Query: 624 DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS--LIEPEQKMTT 681
DEI + + ++I L + QLE+ + D + + E+ + L+ +++
Sbjct: 629 DEIEEKQKIIDEIRDL--NQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA 686
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT-AKQVDFKQKISTLR 740
+ + G + R +Q + + K F V++ V + LD KQKIS L
Sbjct: 687 REDLKGLEETVSRELQTLHNLRKLF--VQDLTTRVKKSVELDNDDGGGSAAQKQKISFLE 744
Query: 741 NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSD 794
N ++ K + L + K ++ L T ++V+ + + L+E+K+ D
Sbjct: 745 NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRD 799
Score = 33.1 bits (72), Expect = 6.2
Identities = 55/270 (20%), Positives = 116/270 (42%), Gaps = 15/270 (5%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEV---TRSMK--VTALAKKKTKFQTLDSFLSTV 122
++A + EVL ++ VN K EV TR+ + LA+K T T LS +
Sbjct: 383 NEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQL 442
Query: 123 DESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIF 182
E + R ++ L+ ++LG I+ + D + ++E + +
Sbjct: 443 QELSNHQ--KKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKM 500
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE 242
++ S ++R K++ + + + + A Q + K S + + E
Sbjct: 501 KSEVKS-LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM--E 557
Query: 243 KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEK 302
+ ++E ++ L E + + ++ ++ K E E++T +Q +AE K + ++
Sbjct: 558 QKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDK--EKEHLTRLQ---DAEEMKKALEQQ 612
Query: 303 VESLKSDHKVQKSQADEEEKKAQGFVDECR 332
+ES + H+ Q S+ +E ++ Q +DE R
Sbjct: 613 MESHREAHQKQLSRLRDEIEEKQKIIDEIR 642
>BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein.
Length = 725
Score = 54.0 bits (124), Expect = 3e-06
Identities = 100/507 (19%), Positives = 210/507 (41%), Gaps = 45/507 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK--EMIEENLKTKEKQLIV 450
+++ EIN+ + E+ +Q+M + + + ++ K++E+ + EN K++ V
Sbjct: 196 LDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEV 255
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVR-NEVXXXXXXXXXXXXXXXXLEAERKH 509
L+ AL EL N +K + E + R NE + E
Sbjct: 256 LQ-----ALEELAVNYDQKS-----QEVEDKTRANE--QLTDELAQKTTTLTTTQRELSQ 303
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++E N ++ T+ + + K G ++ T V+ L D V++ + Y
Sbjct: 304 LQELSNHQKKRATEILNLLLKDLG----EIGGIIGTNDVKTLADVNGVIEEEFTMARLYI 359
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNV----------PGKLEKVTEDLQRA 619
++K + L NR + ES + K++ +T+ +Q
Sbjct: 360 SKMK-SEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 418
Query: 620 SAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
K+ ++ S SL+E++ L+ E E D + + T + EE+ +L EQ+
Sbjct: 419 EQKRRQLEESQDSLSEELAKLRAQE-KMHEVSFQDKEKEHLTRLQDAEEMKKAL---EQQ 474
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE--QCGDVDSEMTLDVATAKQVDFKQKI 736
M + ++ H L R EI+ K + +++ Q ++ E +++ +++
Sbjct: 475 MESHREAH--QKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQERE 532
Query: 737 STLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK-VQDIVNLEESKKQLQSDC 795
L + K+ A + L+ L E ++ + L N +K VQD+ + +L +D
Sbjct: 533 MKLEKLLLLNDKREQA-REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDND- 590
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
I+ LE L++ + ++VR N DL ++ +VK+L+
Sbjct: 591 --DGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALE 648
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLME 882
+ +++ K+N R+ ++ Q+ D++ E
Sbjct: 649 SALKE-AKENAMRDRKRYQQEVDRIKE 674
Score = 38.7 bits (86), Expect = 0.12
Identities = 83/429 (19%), Positives = 179/429 (41%), Gaps = 41/429 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+N K ++V ED RA+ + + L+ K+ T + +++ +L T+I LN
Sbjct: 264 VNYDQKSQEV-EDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEI--LN 320
Query: 663 ETVEEI-TMSLIEPEQKMTTAKQIHG----DMPMLDRYIQEIKTVTKKFEAVKEQC--GD 715
++++ + I + T ++G + M YI ++K+ K +Q
Sbjct: 321 LLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQ 380
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL--LN 773
+DS ++ + + + IS ++K+ + +K + L E + EEL L
Sbjct: 381 MDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLR 440
Query: 774 TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEV------ALKEKIEAKTEVV 827
Q+K+ ++ ++ K+ L + E L+++IE K +++
Sbjct: 441 AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKII 500
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQI 887
RDL + K+ +NK+K D E + ++EK+ NDK + ++ +
Sbjct: 501 DEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREM--------KLEKLLLLNDKREQAREDL 552
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL-NEKLNGIN 946
+ +++++ TL + ++++ +DL + K ++ N +K++ +
Sbjct: 553 KGLEETVSRELQTLHN---LRKLFVQDLTTRV---KKSVELDNDDGGGSAAQKQKISFLE 606
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNE---LEKSLSKDIEKKFRE- 1002
N E L +L + A+ L +L+K L+ LE +L + E R+
Sbjct: 607 ----NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDR 662
Query: 1003 KMYELHVTK 1011
K Y+ V +
Sbjct: 663 KRYQQEVDR 671
Score = 37.5 bits (83), Expect = 0.29
Identities = 77/415 (18%), Positives = 166/415 (40%), Gaps = 22/415 (5%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
E +N ++ QE+ + +A EQ DEL+QK T L +L + + + + K + +
Sbjct: 261 ELAVNYDQKSQEVEDKTRANEQLT---DELAQKTTTLTTTQRELSQLQELSNHQKKRATE 317
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
++ L K L E+ G + D T+ + E L
Sbjct: 318 ILNLLLKD---LGEIGGIIGTND-VKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRS 373
Query: 508 KHIRESLNERRSELTKAEDKIYKACG--TQPYDVTLSKYTTTVEKLQDEQNVLQSSMFII 565
K + + + ++ +E ++ AC ++ + T ++ ++ ++ L+ S +
Sbjct: 374 KQLESAQMDSNRKMNASEREL-AACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSL 432
Query: 566 NKYKGQLKDNSCCPLCNRGFEN-ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR-ASAKK 623
++ +L+ + F++ E E + ++E E Q+ S +
Sbjct: 433 SEELAKLRAQE--KMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLR 490
Query: 624 DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS--LIEPEQKMTT 681
DEI + + ++I L + QLE+ + D + + E+ + L+ +++
Sbjct: 491 DEIEEKQKIIDEIRDL--NQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA 548
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT-AKQVDFKQKISTLR 740
+ + G + R +Q + + K F V++ V + LD KQKIS L
Sbjct: 549 REDLKGLEETVSRELQTLHNLRKLF--VQDLTTRVKKSVELDNDDGGGSAAQKQKISFLE 606
Query: 741 NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSD 794
N ++ K + L + K ++ L T ++V+ + + L+E+K+ D
Sbjct: 607 NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRD 661
Score = 33.1 bits (72), Expect = 6.2
Identities = 55/270 (20%), Positives = 116/270 (42%), Gaps = 15/270 (5%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEV---TRSMK--VTALAKKKTKFQTLDSFLSTV 122
++A + EVL ++ VN K EV TR+ + LA+K T T LS +
Sbjct: 245 NEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQL 304
Query: 123 DESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIF 182
E + R ++ L+ ++LG I+ + D + ++E + +
Sbjct: 305 QELSNHQ--KKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKM 362
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE 242
++ S ++R K++ + + + + A Q + K S + + E
Sbjct: 363 KSEVKS-LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM--E 419
Query: 243 KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEK 302
+ ++E ++ L E + + ++ ++ K E E++T +Q +AE K + ++
Sbjct: 420 QKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDK--EKEHLTRLQ---DAEEMKKALEQQ 474
Query: 303 VESLKSDHKVQKSQADEEEKKAQGFVDECR 332
+ES + H+ Q S+ +E ++ Q +DE R
Sbjct: 475 MESHREAHQKQLSRLRDEIEEKQKIIDEIR 504
>AL138742-1|CAI22698.1| 1325|Homo sapiens KIAA1009 protein.
Length = 1325
Score = 54.0 bits (124), Expect = 3e-06
Identities = 129/697 (18%), Positives = 281/697 (40%), Gaps = 68/697 (9%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+++ Q+EI E E ++ Y+QE + L ++ LQ+Q K E+ M +EN + + +
Sbjct: 625 LKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKK-NEERMFKENQSLFSEVASLKE 683
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
HK+ L V E D T N+ ++ E+ L+ +++ +
Sbjct: 684 QMHKS---RFLSQVVE-DSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEV 739
Query: 513 SLNERRSELTKAEDKIYKACGTQPYDVTLSKYT--TTVEKLQDEQNVLQSSMFIINKYKG 570
+ + E +A+D+I G + Y++ + + T + +LQ + +++K
Sbjct: 740 DFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDAL 799
Query: 571 QLKD-NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L++ N E + K +DL+R + + IL
Sbjct: 800 RLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKR 859
Query: 630 K---SLNEKI-------TTLKDTEIPQLEKRIVDVDTQI--------KTLNETVEEITMS 671
+ SL I T+ + +EKRI ++ + K+L ++
Sbjct: 860 RYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKM 919
Query: 672 LIEPEQKMTTAKQI------HGDMP---MLDRYIQEIK--------TVTKKFEAVKEQCG 714
I+ EQ++ +Q+ D P L++ + +IK + + + +K Q
Sbjct: 920 KIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNA 979
Query: 715 DVD-SEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL---YEKKTKAKEE 770
++D + D + ++F+ + + + ++ ++L A +++Q L E+ K +
Sbjct: 980 ELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRM 1039
Query: 771 LLNTQ-KKVQDIVNLEESKKQ-LQSDCXXXXXXXXXXXXAI--------TPLEVALKEKI 820
+L+ Q K ++ ++ + +KK L S + + + L+E
Sbjct: 1040 MLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENY 1099
Query: 821 EAKTE---VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
K E ++ +L A + + E + +VK A K + RE+EK+ N
Sbjct: 1100 RLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQN 1159
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDE 937
K +R++ T+++ L Q + ++L + + + +I QK+ +
Sbjct: 1160 AVENSSSKVAELNRKIATQEV--LIRHFQSQVNELQSKQESLVVSEVREEIL--QKEITK 1215
Query: 938 LNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE 997
L E+L + E + + + K+ Q + EL++ ++ +E +K++E
Sbjct: 1216 LLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVE 1275
Query: 998 KKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
K +++ +L + ++K E LD L E HR+
Sbjct: 1276 K--WKRLAQLK-NRELEKFRTELDSILD-VLRELHRQ 1308
Score = 33.5 bits (73), Expect = 4.7
Identities = 43/224 (19%), Positives = 94/224 (41%), Gaps = 7/224 (3%)
Query: 817 KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN-KVKSLDAEIQQHKKKNVPREMEKIQE 875
KEK + V+ D A I +++ F+ K K L+ ++++ KK+ +E+ K+ +
Sbjct: 531 KEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQ-EKELFKLNQ 589
Query: 876 ANDKLMEKQKQIM-TDRQVLTKKIDTLKDEIAKQ---EVYKRDLDDNLCLRKAQTDITNW 931
N L K T+++ D + + ++ K + L+ Q +
Sbjct: 590 DNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERL 649
Query: 932 QKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
Q +L E+ N N+E + ++ + + +++ + LS++ + + RN+
Sbjct: 650 YNQVKDLQEQ-NKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTD 708
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
L ++ +EK L K + +D + V +K E + K
Sbjct: 709 LLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAK 752
>AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens cDNA
FLJ10128 fis, clone HEMBA1002997, weakly similar to
CENTROMERIC PROTEIN E. ).
Length = 535
Score = 54.0 bits (124), Expect = 3e-06
Identities = 101/433 (23%), Positives = 196/433 (45%), Gaps = 62/433 (14%)
Query: 611 KVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIP-QLEKRIVDVDTQIKTLNETVEEIT 669
KV+ED++++ + L+ K L+ T K TE ++EK +++ D+ L++ V +
Sbjct: 96 KVSEDMKKSHDAIIDDLNRKLLD---VTQKYTEKKLEMEKLLLENDS----LSKDVSRLE 148
Query: 670 MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ 729
+ PE+ K+I L I E+K K+ +K++CG+ D E + T++
Sbjct: 149 TVFVPPEKH---EKEIIA----LKSNIVELK---KQLSELKKKCGE-DQEK-IHALTSEN 196
Query: 730 VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLE 785
+ K+ +S VKT H + TL + K ELL+ +KK +DI V ++
Sbjct: 197 TNLKKMMSNQYVPVKT-------HEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIK 249
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLI---EAGSAYIA 842
+ + L+ + ++ E + ++ +V N +++ G I
Sbjct: 250 DKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIV 309
Query: 843 KVEVAFN-KVKSLDAEIQQHKKKNVP----REMEKIQEANDKLMEKQKQIMTDRQVLTK- 896
+ + K LD + K K P E E+ +A +K ++ Q T + +++
Sbjct: 310 TLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEE 369
Query: 897 --KIDTLKDEIAKQEVY--KRDL-DDNLCLRKAQTDITNWQKQDDELNEKLNGINK---E 948
K + +++ K+E++ ++DL D + + K+ ++ DELN++L +++ E
Sbjct: 370 EVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQLKDLSQKYTE 429
Query: 949 ELNEKESLI---IKQT-------KLFQQKAECTGALSELKKSLKGFRNELE---KSLSKD 995
N KE L+ KQT L Q++ + LKKSL G L+ KS+ +
Sbjct: 430 VKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRC 489
Query: 996 IEKKFREKMYELH 1008
EK+ ++ + +LH
Sbjct: 490 YEKE-QQTVTKLH 501
Score = 35.1 bits (77), Expect = 1.5
Identities = 49/269 (18%), Positives = 126/269 (46%), Gaps = 25/269 (9%)
Query: 72 VNRSTEVLGQVKLKIVNAKD---KQLEVTRSM---KVTALAKKKTKFQTLDSFLSTVDES 125
V + E + Q +KI + + + LE T++ + +LA+ + K +L + V +S
Sbjct: 234 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 293
Query: 126 GKTKDVSSRCADLDIL-MHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERF------ 178
+ R +I+ +H E+ K L+++ C + + P+ ++ + +F
Sbjct: 294 NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYA-PIVSFEECERKFKATEKE 352
Query: 179 --DEIFD-ADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKE 235
D++ + KYS + +KK +++ + K + ++ K +E S++ + +++
Sbjct: 353 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 412
Query: 236 EEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQ--TNEEAE 293
+++ + +Y + +EK+ + N + +T++I ++N+ + Q E+ E
Sbjct: 413 TDELNKQLKDLSQKYTEV----KNVKEKLVEENAK--QTSEILAVQNLLQKQHVPLEQVE 466
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEK 322
K++ +E+LK + K + ++E++
Sbjct: 467 ALKKSLNGTIENLKEELKSMQRCYEKEQQ 495
>AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein.
Length = 684
Score = 54.0 bits (124), Expect = 3e-06
Identities = 100/507 (19%), Positives = 210/507 (41%), Gaps = 45/507 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK--EMIEENLKTKEKQLIV 450
+++ EIN+ + E+ +Q+M + + + ++ K++E+ + EN K++ V
Sbjct: 155 LDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEV 214
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVR-NEVXXXXXXXXXXXXXXXXLEAERKH 509
L+ AL EL N +K + E + R NE + E
Sbjct: 215 LQ-----ALEELAVNYDQKS-----QEVEDKTRANE--QLTDELAQKTTTLTTTQRELSQ 262
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++E N ++ T+ + + K G ++ T V+ L D V++ + Y
Sbjct: 263 LQELSNHQKKRATEILNLLLKDLG----EIGGIIGTNDVKTLADVNGVIEEEFTMARLYI 318
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNV----------PGKLEKVTEDLQRA 619
++K + L NR + ES + K++ +T+ +Q
Sbjct: 319 SKMK-SEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 377
Query: 620 SAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
K+ ++ S SL+E++ L+ E E D + + T + EE+ +L EQ+
Sbjct: 378 EQKRRQLEESQDSLSEELAKLRAQE-KMHEVSFQDKEKEHLTRLQDAEEMKKAL---EQQ 433
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE--QCGDVDSEMTLDVATAKQVDFKQKI 736
M + ++ H L R EI+ K + +++ Q ++ E +++ +++
Sbjct: 434 MESHREAH--QKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQERE 491
Query: 737 STLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK-VQDIVNLEESKKQLQSDC 795
L + K+ A + L+ L E ++ + L N +K VQD+ + +L +D
Sbjct: 492 MKLEKLLLLNDKREQA-REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDND- 549
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
I+ LE L++ + ++VR N DL ++ +VK+L+
Sbjct: 550 --DGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALE 607
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLME 882
+ +++ K+N R+ ++ Q+ D++ E
Sbjct: 608 SALKE-AKENAMRDRKRYQQEVDRIKE 633
Score = 38.7 bits (86), Expect = 0.12
Identities = 83/429 (19%), Positives = 179/429 (41%), Gaps = 41/429 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+N K ++V ED RA+ + + L+ K+ T + +++ +L T+I LN
Sbjct: 223 VNYDQKSQEV-EDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEI--LN 279
Query: 663 ETVEEI-TMSLIEPEQKMTTAKQIHG----DMPMLDRYIQEIKTVTKKFEAVKEQC--GD 715
++++ + I + T ++G + M YI ++K+ K +Q
Sbjct: 280 LLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQ 339
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL--LN 773
+DS ++ + + + IS ++K+ + +K + L E + EEL L
Sbjct: 340 MDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLR 399
Query: 774 TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEV------ALKEKIEAKTEVV 827
Q+K+ ++ ++ K+ L + E L+++IE K +++
Sbjct: 400 AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKII 459
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQI 887
RDL + K+ +NK+K D E + ++EK+ NDK + ++ +
Sbjct: 460 DEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREM--------KLEKLLLLNDKREQAREDL 511
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL-NEKLNGIN 946
+ +++++ TL + ++++ +DL + K ++ N +K++ +
Sbjct: 512 KGLEETVSRELQTLHN---LRKLFVQDLTTRV---KKSVELDNDDGGGSAAQKQKISFLE 565
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNE---LEKSLSKDIEKKFRE- 1002
N E L +L + A+ L +L+K L+ LE +L + E R+
Sbjct: 566 ----NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDR 621
Query: 1003 KMYELHVTK 1011
K Y+ V +
Sbjct: 622 KRYQQEVDR 630
Score = 37.5 bits (83), Expect = 0.29
Identities = 77/415 (18%), Positives = 166/415 (40%), Gaps = 22/415 (5%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
E +N ++ QE+ + +A EQ DEL+QK T L +L + + + + K + +
Sbjct: 220 ELAVNYDQKSQEVEDKTRANEQLT---DELAQKTTTLTTTQRELSQLQELSNHQKKRATE 276
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
++ L K L E+ G + D T+ + E L
Sbjct: 277 ILNLLLKD---LGEIGGIIGTND-VKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRS 332
Query: 508 KHIRESLNERRSELTKAEDKIYKACG--TQPYDVTLSKYTTTVEKLQDEQNVLQSSMFII 565
K + + + ++ +E ++ AC ++ + T ++ ++ ++ L+ S +
Sbjct: 333 KQLESAQMDSNRKMNASEREL-AACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSL 391
Query: 566 NKYKGQLKDNSCCPLCNRGFEN-ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR-ASAKK 623
++ +L+ + F++ E E + ++E E Q+ S +
Sbjct: 392 SEELAKLRAQE--KMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLR 449
Query: 624 DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS--LIEPEQKMTT 681
DEI + + ++I L + QLE+ + D + + E+ + L+ +++
Sbjct: 450 DEIEEKQKIIDEIRDL--NQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA 507
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT-AKQVDFKQKISTLR 740
+ + G + R +Q + + K F V++ V + LD KQKIS L
Sbjct: 508 REDLKGLEETVSRELQTLHNLRKLF--VQDLTTRVKKSVELDNDDGGGSAAQKQKISFLE 565
Query: 741 NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSD 794
N ++ K + L + K ++ L T ++V+ + + L+E+K+ D
Sbjct: 566 NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRD 620
Score = 33.1 bits (72), Expect = 6.2
Identities = 55/270 (20%), Positives = 116/270 (42%), Gaps = 15/270 (5%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEV---TRSMK--VTALAKKKTKFQTLDSFLSTV 122
++A + EVL ++ VN K EV TR+ + LA+K T T LS +
Sbjct: 204 NEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQL 263
Query: 123 DESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIF 182
E + R ++ L+ ++LG I+ + D + ++E + +
Sbjct: 264 QELSNHQ--KKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKM 321
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE 242
++ S ++R K++ + + + + A Q + K S + + E
Sbjct: 322 KSEVKS-LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM--E 378
Query: 243 KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEK 302
+ ++E ++ L E + + ++ ++ K E E++T +Q +AE K + ++
Sbjct: 379 QKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDK--EKEHLTRLQ---DAEEMKKALEQQ 433
Query: 303 VESLKSDHKVQKSQADEEEKKAQGFVDECR 332
+ES + H+ Q S+ +E ++ Q +DE R
Sbjct: 434 MESHREAHQKQLSRLRDEIEEKQKIIDEIR 463
>AB040945-1|BAA96036.2| 2010|Homo sapiens KIAA1512 protein protein.
Length = 2010
Score = 54.0 bits (124), Expect = 3e-06
Identities = 109/525 (20%), Positives = 217/525 (41%), Gaps = 48/525 (9%)
Query: 603 MNVPGKLEKVTEDLQ-RASAKKDEILSMKSLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + GK+++++E L+ D + L ++ T LK D E+ + EK +
Sbjct: 989 VQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATE 1048
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGD-MPMLDRYIQEIKTVTKKFEAVKEQCG 714
++K L E + + S+ ++ ++ H + L + +TK +++Q
Sbjct: 1049 NKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVE 1108
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D+ E +L+ ++D ++ L +K TQ+ + + Q L EK K EL
Sbjct: 1109 DL--ECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1166
Query: 775 QKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
+V+D +++ K+LQ+ A +E K++ EA E+ +
Sbjct: 1167 SLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVE---KQRAEAARELEELS 1223
Query: 831 RDLIEAGSAYIA------KVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
L EAG A K E +++ E + V K E +L E+
Sbjct: 1224 ERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQV 1283
Query: 885 KQIMTDRQVLTKKIDTLKDEI----AKQEVYKR--DLDDNLCLRKAQTDITNWQKQDDEL 938
+ RQ L K+ L+ E+ A E R + LC R + ++ + + +EL
Sbjct: 1284 DSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLC-RTYEDQLSEAKIKVEEL 1342
Query: 939 NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+L + + ++ + ++L ++K EC +S+L + K + + L + +E+
Sbjct: 1343 QRQLADASTQR-GRLQTESGELSRLLEEK-EC--LISQLSRG-KALAAQSLEELRRQLEE 1397
Query: 999 KFREKMYELHVTKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGND 1055
+ + K H +A+ D +RE + E R + N + + WR Y +
Sbjct: 1398 ESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQR-LLSKANAEVAQ-WRSKYEADA 1455
Query: 1056 IDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQK 1100
I +TE +E ++K R+ +++ GVE +CS+ +K
Sbjct: 1456 IQ----RTE---ELEEAKKKLALRLQEAEEGVEA-ANAKCSSLEK 1492
Score = 43.6 bits (98), Expect = 0.004
Identities = 84/425 (19%), Positives = 169/425 (39%), Gaps = 27/425 (6%)
Query: 617 QRASAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
Q+ +K E+ + + L + TL + EK + Q+ VEE+ L +
Sbjct: 1291 QKLEKEKSELRMEVDDLAANVETLTRAKA-SAEKLCRTYEDQLSEAKIKVEELQRQLADA 1349
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT--LDVATAKQVDFK 733
+ + G+ L R ++E + + + K E+ L+ + +
Sbjct: 1350 STQRGRLQTESGE---LSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALA 1406
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK-----VQDIVNLEESK 788
+ LR+ +++ + L +KA E+ + K +Q LEE+K
Sbjct: 1407 HAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAK 1466
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
K+L + LE K K+ +TE +L A SA A +
Sbjct: 1467 KKLALRLQEAEEGVEAANAKCSSLE---KAKLRLQTESEDVTLELERATSAAAALDKKQR 1523
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
+ ++L E ++ +++ + RE+E Q + L + ++ + + ++TLK E
Sbjct: 1524 HLERAL--EERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNL 1581
Query: 909 EVYKRDLDDNLCLR-KAQTDITNWQKQDDELNEKLNGINKE-----ELNEKESLIIKQTK 962
+ DL D + L K+ ++ +K + ++ +E EL E ++L I Q +
Sbjct: 1582 QEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRI-QLE 1640
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEK---SLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
L Q KAE L+E + R ++ SL ++ + R + L + K ++ D+ +
Sbjct: 1641 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1700
Query: 1020 YAVAL 1024
+ L
Sbjct: 1701 LELQL 1705
Score = 37.5 bits (83), Expect = 0.29
Identities = 75/392 (19%), Positives = 156/392 (39%), Gaps = 29/392 (7%)
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K+L E+I+ L D ++ K I +++ K L EI +L E E + +
Sbjct: 1579 KNLQEEISDLTD-QVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEET---KT 1634
Query: 690 PMLDRYIQEIKT-VTKKFEAVKEQCGDVDSEMTLDVATAK-QVDFKQKISTLRNRVKTTQ 747
+ + ++K V +K E+C ++ V + + +D + + RN +
Sbjct: 1635 LRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRA---RNEALRLK 1691
Query: 748 KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXX 807
KK+ L+ T+ E + +Q + E++ + +
Sbjct: 1692 KKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALE 1751
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK--- 864
L A E++ A E R+R L E + + N + S + + KKK
Sbjct: 1752 RRASLLAAELEELRAALEQGERSRRLAEQE---LLEATERLNLLHSQNTGLLNQKKKLEA 1808
Query: 865 ---NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
+ E+E+ + + EK K+ +TD ++ +++ +D A E K+ L+ +
Sbjct: 1809 DLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRE 1868
Query: 922 RKA------QTDITNWQKQDDELNEKLNGINKE--ELNEKESLIIKQTKLFQQKA-ECTG 972
+A Q + +KQ +L K+ + E +K + +K + +++ E
Sbjct: 1869 LQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAY 1928
Query: 973 ALSELKKSLKGFRNELEK--SLSKDIEKKFRE 1002
E +K+L ++ ++K S K +++F E
Sbjct: 1929 QAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1960
Score = 33.9 bits (74), Expect = 3.5
Identities = 62/311 (19%), Positives = 132/311 (42%), Gaps = 29/311 (9%)
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDL---IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
A+ E +E E + + DL ++A +A E + + +++ K K
Sbjct: 938 ALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEG-KVK 996
Query: 865 NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD---NLCL 921
+ +E +E N L +++++ + L K ID L+ +AK E K+ ++ NL
Sbjct: 997 ELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTE 1056
Query: 922 RKAQTD--ITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKK 979
A D + K+ L E +++ L + ++ + + L + K + +L+
Sbjct: 1057 EMAALDESVARLTKEKKALQE----AHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLEC 1112
Query: 980 SLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE----- 1034
SL E EK L D E+ R+ +L +T+ D + L++ L + E
Sbjct: 1113 SL-----EQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLS 1167
Query: 1035 -KMENINMIIRELWRKI----YRGNDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEI 1089
++E+ ++ ++ +KI R +++ E++ E E+++ + + +
Sbjct: 1168 LRVEDEQLLGAQMQKKIKELQARAEELEE-ELEAERAARARVEKQRAEAARELEELSERL 1226
Query: 1090 DMRGRCSAGQK 1100
+ G SAGQ+
Sbjct: 1227 EEAGGASAGQR 1237
>AB023226-1|BAA76853.2| 1345|Homo sapiens KIAA1009 protein protein.
Length = 1345
Score = 54.0 bits (124), Expect = 3e-06
Identities = 129/697 (18%), Positives = 281/697 (40%), Gaps = 68/697 (9%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+++ Q+EI E E ++ Y+QE + L ++ LQ+Q K E+ M +EN + + +
Sbjct: 645 LKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKK-NEERMFKENQSLFSEVASLKE 703
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
HK+ L V E D T N+ ++ E+ L+ +++ +
Sbjct: 704 QMHKS---RFLSQVVE-DSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEV 759
Query: 513 SLNERRSELTKAEDKIYKACGTQPYDVTLSKYT--TTVEKLQDEQNVLQSSMFIINKYKG 570
+ + E +A+D+I G + Y++ + + T + +LQ + +++K
Sbjct: 760 DFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDAL 819
Query: 571 QLKD-NSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
+L++ N E + K +DL+R + + IL
Sbjct: 820 RLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKR 879
Query: 630 K---SLNEKI-------TTLKDTEIPQLEKRIVDVDTQI--------KTLNETVEEITMS 671
+ SL I T+ + +EKRI ++ + K+L ++
Sbjct: 880 RYPNSLPALILAASAAGDTVDKNTVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKM 939
Query: 672 LIEPEQKMTTAKQI------HGDMP---MLDRYIQEIK--------TVTKKFEAVKEQCG 714
I+ EQ++ +Q+ D P L++ + +IK + + + +K Q
Sbjct: 940 KIQYEQRLEQQEQLLACKLNQHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNA 999
Query: 715 DVD-SEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTL---YEKKTKAKEE 770
++D + D + ++F+ + + + ++ ++L A +++Q L E+ K +
Sbjct: 1000 ELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRM 1059
Query: 771 LLNTQ-KKVQDIVNLEESKKQ-LQSDCXXXXXXXXXXXXAI--------TPLEVALKEKI 820
+L+ Q K ++ ++ + +KK L S + + + L+E
Sbjct: 1060 MLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENY 1119
Query: 821 EAKTE---VVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAN 877
K E ++ +L A + + E + +VK A K + RE+EK+ N
Sbjct: 1120 RLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQN 1179
Query: 878 DKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDE 937
K +R++ T+++ L Q + ++L + + + +I QK+ +
Sbjct: 1180 AVENSSSKVAELNRKIATQEV--LIRHFQSQVNELQSKQESLVVSEVREEIL--QKEITK 1235
Query: 938 LNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE 997
L E+L + E + + + K+ Q + EL++ ++ +E +K++E
Sbjct: 1236 LLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVE 1295
Query: 998 KKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
K +++ +L + ++K E LD L E HR+
Sbjct: 1296 K--WKRLAQLK-NRELEKFRTELDSILD-VLRELHRQ 1328
Score = 33.5 bits (73), Expect = 4.7
Identities = 43/224 (19%), Positives = 94/224 (41%), Gaps = 7/224 (3%)
Query: 817 KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFN-KVKSLDAEIQQHKKKNVPREMEKIQE 875
KEK + V+ D A I +++ F+ K K L+ ++++ KK+ +E+ K+ +
Sbjct: 551 KEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQ-EKELFKLNQ 609
Query: 876 ANDKLMEKQKQIM-TDRQVLTKKIDTLKDEIAKQ---EVYKRDLDDNLCLRKAQTDITNW 931
N L K T+++ D + + ++ K + L+ Q +
Sbjct: 610 DNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERL 669
Query: 932 QKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKS 991
Q +L E+ N N+E + ++ + + +++ + LS++ + + RN+
Sbjct: 670 YNQVKDLQEQ-NKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTD 728
Query: 992 LSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREK 1035
L ++ +EK L K + +D + V +K E + K
Sbjct: 729 LLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAK 772
>AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein.
Length = 999
Score = 54.0 bits (124), Expect = 3e-06
Identities = 100/507 (19%), Positives = 210/507 (41%), Gaps = 45/507 (8%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK--EMIEENLKTKEKQLIV 450
+++ EIN+ + E+ +Q+M + + + ++ K++E+ + EN K++ V
Sbjct: 470 LDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEV 529
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVR-NEVXXXXXXXXXXXXXXXXLEAERKH 509
L+ AL EL N +K + E + R NE + E
Sbjct: 530 LQ-----ALEELAVNYDQKS-----QEVEDKTRANE--QLTDELAQKTTTLTTTQRELSQ 577
Query: 510 IRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++E N ++ T+ + + K G ++ T V+ L D V++ + Y
Sbjct: 578 LQELSNHQKKRATEILNLLLKDLG----EIGGIIGTNDVKTLADVNGVIEEEFTMARLYI 633
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNV----------PGKLEKVTEDLQRA 619
++K + L NR + ES + K++ +T+ +Q
Sbjct: 634 SKMK-SEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM 692
Query: 620 SAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
K+ ++ S SL+E++ L+ E E D + + T + EE+ +L EQ+
Sbjct: 693 EQKRRQLEESQDSLSEELAKLRAQE-KMHEVSFQDKEKEHLTRLQDAEEMKKAL---EQQ 748
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKE--QCGDVDSEMTLDVATAKQVDFKQKI 736
M + ++ H L R EI+ K + +++ Q ++ E +++ +++
Sbjct: 749 MESHREAH--QKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQERE 806
Query: 737 STLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK-VQDIVNLEESKKQLQSDC 795
L + K+ A + L+ L E ++ + L N +K VQD+ + +L +D
Sbjct: 807 MKLEKLLLLNDKREQA-REDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDND- 864
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLD 855
I+ LE L++ + ++VR N DL ++ +VK+L+
Sbjct: 865 --DGGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALE 922
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLME 882
+ +++ K+N R+ ++ Q+ D++ E
Sbjct: 923 SALKE-AKENAMRDRKRYQQEVDRIKE 948
Score = 38.7 bits (86), Expect = 0.12
Identities = 83/429 (19%), Positives = 179/429 (41%), Gaps = 41/429 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLN 662
+N K ++V ED RA+ + + L+ K+ T + +++ +L T+I LN
Sbjct: 538 VNYDQKSQEV-EDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEI--LN 594
Query: 663 ETVEEI-TMSLIEPEQKMTTAKQIHG----DMPMLDRYIQEIKTVTKKFEAVKEQC--GD 715
++++ + I + T ++G + M YI ++K+ K +Q
Sbjct: 595 LLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQ 654
Query: 716 VDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL--LN 773
+DS ++ + + + IS ++K+ + +K + L E + EEL L
Sbjct: 655 MDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSLSEELAKLR 714
Query: 774 TQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEV------ALKEKIEAKTEVV 827
Q+K+ ++ ++ K+ L + E L+++IE K +++
Sbjct: 715 AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDEIEEKQKII 774
Query: 828 RRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQI 887
RDL + K+ +NK+K D E + ++EK+ NDK + ++ +
Sbjct: 775 DEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREM--------KLEKLLLLNDKREQAREDL 826
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL-NEKLNGIN 946
+ +++++ TL + ++++ +DL + K ++ N +K++ +
Sbjct: 827 KGLEETVSRELQTLHN---LRKLFVQDLTTRV---KKSVELDNDDGGGSAAQKQKISFLE 880
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNE---LEKSLSKDIEKKFRE- 1002
N E L +L + A+ L +L+K L+ LE +L + E R+
Sbjct: 881 ----NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDR 936
Query: 1003 KMYELHVTK 1011
K Y+ V +
Sbjct: 937 KRYQQEVDR 945
Score = 37.5 bits (83), Expect = 0.29
Identities = 77/415 (18%), Positives = 166/415 (40%), Gaps = 22/415 (5%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQ 447
E +N ++ QE+ + +A EQ DEL+QK T L +L + + + + K + +
Sbjct: 535 ELAVNYDQKSQEVEDKTRANEQLT---DELAQKTTTLTTTQRELSQLQELSNHQKKRATE 591
Query: 448 LIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAER 507
++ L K L E+ G + D T+ + E L
Sbjct: 592 ILNLLLKD---LGEIGGIIGTND-VKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRS 647
Query: 508 KHIRESLNERRSELTKAEDKIYKACG--TQPYDVTLSKYTTTVEKLQDEQNVLQSSMFII 565
K + + + ++ +E ++ AC ++ + T ++ ++ ++ L+ S +
Sbjct: 648 KQLESAQMDSNRKMNASEREL-AACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSL 706
Query: 566 NKYKGQLKDNSCCPLCNRGFEN-ESEXXXXXXXXXXXXMNVPGKLEKVTEDLQR-ASAKK 623
++ +L+ + F++ E E + ++E E Q+ S +
Sbjct: 707 SEELAKLRAQE--KMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLR 764
Query: 624 DEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMS--LIEPEQKMTT 681
DEI + + ++I L + QLE+ + D + + E+ + L+ +++
Sbjct: 765 DEIEEKQKIIDEIRDL--NQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQA 822
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT-AKQVDFKQKISTLR 740
+ + G + R +Q + + K F V++ V + LD KQKIS L
Sbjct: 823 REDLKGLEETVSRELQTLHNLRKLF--VQDLTTRVKKSVELDNDDGGGSAAQKQKISFLE 880
Query: 741 NRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSD 794
N ++ K + L + K ++ L T ++V+ + + L+E+K+ D
Sbjct: 881 NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRD 935
Score = 33.1 bits (72), Expect = 6.2
Identities = 55/270 (20%), Positives = 116/270 (42%), Gaps = 15/270 (5%)
Query: 68 HDAKVNRSTEVLGQVKLKIVNAKDKQLEV---TRSMK--VTALAKKKTKFQTLDSFLSTV 122
++A + EVL ++ VN K EV TR+ + LA+K T T LS +
Sbjct: 519 NEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQL 578
Query: 123 DESGKTKDVSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIF 182
E + R ++ L+ ++LG I+ + D + ++E + +
Sbjct: 579 QELSNHQ--KKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKM 636
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANE 242
++ S ++R K++ + + + + A Q + K S + + E
Sbjct: 637 KSEVKS-LVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNM--E 693
Query: 243 KSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEK 302
+ ++E ++ L E + + ++ ++ K E E++T +Q +AE K + ++
Sbjct: 694 QKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDK--EKEHLTRLQ---DAEEMKKALEQQ 748
Query: 303 VESLKSDHKVQKSQADEEEKKAQGFVDECR 332
+ES + H+ Q S+ +E ++ Q +DE R
Sbjct: 749 MESHREAHQKQLSRLRDEIEEKQKIIDEIR 778
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (1151
AA) protein.
Length = 1151
Score = 53.6 bits (123), Expect = 4e-06
Identities = 113/562 (20%), Positives = 243/562 (43%), Gaps = 54/562 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 129 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 188
Query: 656 TQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
++K L E + +EI L + ++ + A Q D + ++ T+TK +++Q
Sbjct: 189 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLTKAKVKLEQQ 246
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D++ +L+ ++D ++ L +K TQ+ + Q L E+ K EL
Sbjct: 247 VDDLEG--SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLEERLKKKDFELN 304
Query: 773 NTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+++D L++ K+LQ+ A +E K + + E+
Sbjct: 305 ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE---KLRSDLSRELEE 361
Query: 829 RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+ L EAG A V++ NK + +AE Q+ ++++ + + L +K +
Sbjct: 362 ISERLEEAGGA--TSVQIEMNKKR--EAEFQK-MRRDLEEATLQHEATAAALRKKHADSV 416
Query: 889 TDRQVLTKKIDTLKDEIAKQE-VYKRDLDD---NL-CLRKAQTDITNW-QKQDDELNEKL 942
+ + +K ++ K++ +K +LDD N+ + KA+ ++ + +D++NE
Sbjct: 417 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR 476
Query: 943 NGINKEE------LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
+ + + +++ L + +L +Q E +S+L + + +LE L + +
Sbjct: 477 SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE-DLKRQL 535
Query: 997 EKKFREKMYELHVTKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRG 1053
E++ + K H ++ D +RE + E R + N + + WR Y
Sbjct: 536 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR-VLSKANSEVAQ-WRTKY-- 591
Query: 1054 NDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACL--IIRLAL 1111
+ D I+ +TE +E ++K R+ +++ VE + +CS+ +K L I +
Sbjct: 592 -ETDAIQ-RTE---ELEEAKKKLAQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLM 645
Query: 1112 AETFSSRFGILALDEPTTNLDQ 1133
+ S ALD+ N D+
Sbjct: 646 VDVERSNAAAAALDKKQRNFDK 667
Score = 52.8 bits (121), Expect = 7e-06
Identities = 161/845 (19%), Positives = 346/845 (40%), Gaps = 83/845 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ + +++K+R D ++ L+ + E A ++E + K+ F K
Sbjct: 332 EELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 389
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K + +V
Sbjct: 390 MRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 448
Query: 288 TNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXX 346
+N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 449 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLD 508
Query: 347 XXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA 406
+T Q +A+N L Q ++ +
Sbjct: 509 EKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARHDCDLL 559
Query: 407 VEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E L K K L E
Sbjct: 560 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAE 617
Query: 464 GNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V + + + K + ++NE+ L+ ++++ + L E + +
Sbjct: 618 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 677
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPL 580
+++ ++ + Q +LS T + KL+ N + S+ + +K + K+ L
Sbjct: 678 ESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQEEISDL 728
Query: 581 CNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLN 633
+ G ++ E M + LE+ L+ K + E +K+
Sbjct: 729 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 788
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD+ ++
Sbjct: 789 ERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGDLNEME 842
Query: 694 RYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + + + D+++ LD A D K+ I+ + R Q +L
Sbjct: 843 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 902
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
++ + A EEL+ T ++VQ + +L KK++ +D
Sbjct: 903 ELRAVVEQTERSRKLADEELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ-------- 954
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP 867
T +E A++E A+ + + D +A +A+ K + A +++ KKN+
Sbjct: 955 --TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-MKKNME 1003
Query: 868 REMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
+ ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +RK++
Sbjct: 1004 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGMRKSER 1061
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
I Q +E ++ N + ++L +K L +K K ++AE A + L K K ++
Sbjct: 1062 RIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFRK-VQH 1117
Query: 987 ELEKS 991
EL+++
Sbjct: 1118 ELDEA 1122
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase 1 protein.
Length = 1354
Score = 53.6 bits (123), Expect = 4e-06
Identities = 74/360 (20%), Positives = 150/360 (41%), Gaps = 25/360 (6%)
Query: 662 NETVEEITMSLIEPEQKMT--TAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSE 719
N T SL E QK +Q+H +M + D Q+ +T K + + ++ + ++
Sbjct: 414 NRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQ 473
Query: 720 MTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQ 779
+T Q++ K+K+ L++R+ Q+K N+K + + + + K +L + +K Q
Sbjct: 474 RRNLESTVSQIE-KEKM-LLQHRINEYQRKAEQENEKRRNVENEVSTLKNQLEDLKKVSQ 531
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSA 839
+ E QLQ L + E ++ +++ NR+L E
Sbjct: 532 NSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQE---- 587
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKID 899
+ + N D + Q E E+ +D M Q L +++
Sbjct: 588 ---RNRILENSKSQTDKDYYQ---LQAILEAERRDRGHDSEMIGDLQARITS--LQEEVK 639
Query: 900 TLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGIN---KEELNEKESL 956
LK + K E +++ D L ++ + N + +LN KL + ++E+NE +
Sbjct: 640 HLKHNLEKVEGERKEAQD--MLNHSEKEKNN---LEIDLNYKLKSLQQRLEQEVNEHKVT 694
Query: 957 IIKQTKLFQQKAECTG-ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
+ T Q E A+ E++K LK R EK+ ++ ++ + + M ++ + ++ K
Sbjct: 695 KARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQK 754
Score = 51.6 bits (118), Expect = 2e-05
Identities = 131/642 (20%), Positives = 269/642 (41%), Gaps = 67/642 (10%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK- 452
E Q+ I + E+ + Q DE+ QK + K+ KE+ EE + + + V +
Sbjct: 426 ESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIM-KELDEEGNQRRNLESTVSQI 484
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLE-AERK--H 509
K K L + K A N+ V NEV + A K
Sbjct: 485 EKEKMLLQHRINEYQRK--AEQENEKRRNVENEVSTLKNQLEDLKKVSQNSQLANEKLSQ 542
Query: 510 IRESLNERRSEL-TKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKY 568
+++ L E L T+++ + ++S+ + +LQ+ +L++S +K
Sbjct: 543 LQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKD 602
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS 628
QL+ +RG ++E ++ +++ + +L++ ++ E
Sbjct: 603 YYQLQAILEAERRDRGHDSEM-----IGDLQARITSLQEEVKHLKHNLEKVEGERKEAQD 657
Query: 629 MKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE------ITMS-LIEPEQKMTT 681
M + +EK E LE +D++ ++K+L + +E+ +T + L + Q +
Sbjct: 658 MLNHSEK-------EKNNLE---IDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEE 707
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFE----AVKEQCGDVDSEMTLDVATAKQVDFKQKIS 737
AK + M +++ ++E + +K E +++QC +D ++ + + ++
Sbjct: 708 AKSVA--MCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKE-- 763
Query: 738 TLRNRVKTTQKKLNAH-NKKLQTLYEKKTKAKE--ELLNTQKKV-QDIVNLEESKKQLQS 793
+ + VK +L NK+L E KT+A E L +K++ Q+I L E+K+ L+
Sbjct: 764 RMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEF 823
Query: 794 DCXXXXXXXXXXXXAITPLEVALKEK----IEAKTEVVRRNRDLIEAGSAYIAKVEVAFN 849
+ + L+ L+ + KT+V ++ E + K++ N
Sbjct: 824 ELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQN 883
Query: 850 KVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA-KQ 908
+ ++L ++ + K E E++ L+E+Q +T Q K + EI K
Sbjct: 884 EKETLATQLDLAETK---AESEQLARG---LLEEQYFELT--QESKKAASRNRQEITDKD 935
Query: 909 EVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ-- 966
R + N L K DI +++++EL E++ +E EKE I F++
Sbjct: 936 HTVSRLEEANSMLTK---DIEILRRENEELTERMKKAEEEYKLEKEEEISNLKAAFEKNI 992
Query: 967 ------KAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
K + L+E+ + K F+ + +K+ ++D+ KK +E
Sbjct: 993 NTERTLKTQAVNKLAEI-MNRKDFKIDRKKANTQDLRKKEKE 1033
Score = 51.2 bits (117), Expect = 2e-05
Identities = 116/596 (19%), Positives = 243/596 (40%), Gaps = 50/596 (8%)
Query: 397 QQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHK 456
Q INE ++ EQ ++ + +++ L+ Q LK+ + +N + ++L L+ + +
Sbjct: 492 QHRINEYQRKAEQENEKRRNVENEVSTLKNQLEDLKK---VSQNSQLANEKLSQLQKQLE 548
Query: 457 TALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE 516
A +LL E D AV + K E+ + LE + + +
Sbjct: 549 EA-NDLLRT--ESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQ 605
Query: 517 RRSEL-TKAEDKIYKA--CGTQPYDVT-----LSKYTTTVEKLQDEQNVLQSSMFIINKY 568
++ L + D+ + + G +T + +EK++ E+ Q + K
Sbjct: 606 LQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKE 665
Query: 569 KGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS 628
K L+ + L + E E + K + + E A + ++ L
Sbjct: 666 KNNLEIDLNYKLKSLQQRLEQEVNEHKVTKA----RLTDKHQSIEEAKSVAMCEMEKKLK 721
Query: 629 M-KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT--MSLIEPEQKMTTAKQI 685
+ EK + + Q+EK+ +D +K + +E +T +E E K T Q+
Sbjct: 722 EEREAREKA----ENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTL-QL 776
Query: 686 HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNR--- 742
+ E+KT + + +K + E+ + + ++F+ T + R
Sbjct: 777 EQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNE 836
Query: 743 --VKTTQKKLNAHNKKLQTLYEKKTKA-KEELLNTQKK-VQDIVNLEESKKQLQSDCXXX 798
++ Q +L A + TLY+ + K KEE+ ++ ++ I L+ K+ L +
Sbjct: 837 GQMRELQDQLEAE-QYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLA 895
Query: 799 XXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEI 858
A LE E + + RNR I ++++E A N + + D EI
Sbjct: 896 ETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEA-NSMLTKDIEI 954
Query: 859 QQHKKKNVPREMEKIQEANDKLMEKQ---------KQIMTDRQVLTKKIDTLKDEIAKQE 909
+ + + + M+K +E E++ K I T+R + T+ ++ L EI ++
Sbjct: 955 LRRENEELTERMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLA-EIMNRK 1013
Query: 910 VYK--RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGI---NKEELNEKESLIIKQ 960
+K R + LRK + + Q + ++ EK N + +++ELN+ ++ ++++
Sbjct: 1014 DFKIDRKKANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEE 1069
Score = 35.9 bits (79), Expect = 0.88
Identities = 41/163 (25%), Positives = 74/163 (45%), Gaps = 12/163 (7%)
Query: 170 EGKKVKERF-DEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKK 228
E KK R EI D D + RL++ +++++L + + K+ E+ YK
Sbjct: 919 ESKKAASRNRQEITDKDH---TVSRLEEANSMLTKDIEILRRENEELTERMKKAEEEYKL 975
Query: 229 NTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIENITEVQT 288
++EE+I+N K++ E N L++Q K+ + + + KI + T+
Sbjct: 976 -----EKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNR--KDFKIDRKKANTQDLR 1028
Query: 289 NEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDEC 331
+E EN + E K + V K Q + + +AQ V+EC
Sbjct: 1029 KKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQ-LVEEC 1070
>AL133324-2|CAI19310.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 53.6 bits (123), Expect = 4e-06
Identities = 111/514 (21%), Positives = 216/514 (42%), Gaps = 50/514 (9%)
Query: 610 EKVTEDLQRASAK-KDEILSMKS-LNE-KITTLK-DTEIPQLEKRIVDVDTQIKTLNETV 665
E+V DL K +DE +K +++ K+T K + E E ++ ++ ++ L+E+V
Sbjct: 979 EEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESV 1038
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
+T E + +Q GD+ + + +TK +++Q D+ E +L+
Sbjct: 1039 ARLTK---EKKALQEAHQQALGDLQAEE---DRVSALTKAKLRLEQQVEDL--ECSLEQE 1090
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI---- 781
++D ++ L +K TQ+ + + Q L EK K EL +V+D
Sbjct: 1091 KKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLG 1150
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
+++ K+LQ+ A +E K++ EA E+ + L EAG A
Sbjct: 1151 AQMQKKIKELQARAEELEEELEAERAARARVE---KQRAEAARELEELSERLEEAGGASA 1207
Query: 842 A------KVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLT 895
K E +++ E + V K E +L E+ + RQ L
Sbjct: 1208 GQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLE 1267
Query: 896 KKIDTLKDEI----AKQEVYKR--DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
K+ L+ E+ A E R + LC R + ++ + + +EL +L + +
Sbjct: 1268 KEKSELRMEVDDLAANVETLTRAKASAEKLC-RTYEDQLSEAKIKVEELQRQLADASTQR 1326
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
++ + ++L ++K EC +S+L + K + + L + +E++ + K H
Sbjct: 1327 -GRLQTESGELSRLLEEK-EC--LISQLSRG-KALAAQSLEELRRQLEEESKAKSALAHA 1381
Query: 1010 TKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGN 1066
+A+ D +RE + E R + N + + WR Y + I +TE
Sbjct: 1382 VQALRHDCDLLREQHEEEAEAQAELQR-LLSKANAEVAQ-WRSKYEADAIQ----RTE-- 1433
Query: 1067 LTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQK 1100
+E ++K R+ +++ GVE +CS+ +K
Sbjct: 1434 -ELEEAKKKLALRLQEAEEGVEA-ANAKCSSLEK 1465
Score = 43.6 bits (98), Expect = 0.004
Identities = 84/425 (19%), Positives = 169/425 (39%), Gaps = 27/425 (6%)
Query: 617 QRASAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
Q+ +K E+ + + L + TL + EK + Q+ VEE+ L +
Sbjct: 1264 QKLEKEKSELRMEVDDLAANVETLTRAKA-SAEKLCRTYEDQLSEAKIKVEELQRQLADA 1322
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT--LDVATAKQVDFK 733
+ + G+ L R ++E + + + K E+ L+ + +
Sbjct: 1323 STQRGRLQTESGE---LSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALA 1379
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK-----VQDIVNLEESK 788
+ LR+ +++ + L +KA E+ + K +Q LEE+K
Sbjct: 1380 HAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAK 1439
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
K+L + LE K K+ +TE +L A SA A +
Sbjct: 1440 KKLALRLQEAEEGVEAANAKCSSLE---KAKLRLQTESEDVTLELERATSAAAALDKKQR 1496
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
+ ++L E ++ +++ + RE+E Q + L + ++ + + ++TLK E
Sbjct: 1497 HLERAL--EERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNL 1554
Query: 909 EVYKRDLDDNLCLR-KAQTDITNWQKQDDELNEKLNGINKE-----ELNEKESLIIKQTK 962
+ DL D + L K+ ++ +K + ++ +E EL E ++L I Q +
Sbjct: 1555 QEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRI-QLE 1613
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEK---SLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
L Q KAE L+E + R ++ SL ++ + R + L + K ++ D+ +
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1673
Query: 1020 YAVAL 1024
+ L
Sbjct: 1674 LELQL 1678
Score = 37.5 bits (83), Expect = 0.29
Identities = 75/392 (19%), Positives = 156/392 (39%), Gaps = 29/392 (7%)
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K+L E+I+ L D ++ K I +++ K L EI +L E E + +
Sbjct: 1552 KNLQEEISDLTD-QVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEET---KT 1607
Query: 690 PMLDRYIQEIKT-VTKKFEAVKEQCGDVDSEMTLDVATAK-QVDFKQKISTLRNRVKTTQ 747
+ + ++K V +K E+C ++ V + + +D + + RN +
Sbjct: 1608 LRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRA---RNEALRLK 1664
Query: 748 KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXX 807
KK+ L+ T+ E + +Q + E++ + +
Sbjct: 1665 KKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALE 1724
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK--- 864
L A E++ A E R+R L E + + N + S + + KKK
Sbjct: 1725 RRASLLAAELEELRAALEQGERSRRLAEQE---LLEATERLNLLHSQNTGLLNQKKKLEA 1781
Query: 865 ---NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
+ E+E+ + + EK K+ +TD ++ +++ +D A E K+ L+ +
Sbjct: 1782 DLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRE 1841
Query: 922 RKA------QTDITNWQKQDDELNEKLNGINKE--ELNEKESLIIKQTKLFQQKA-ECTG 972
+A Q + +KQ +L K+ + E +K + +K + +++ E
Sbjct: 1842 LQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAY 1901
Query: 973 ALSELKKSLKGFRNELEK--SLSKDIEKKFRE 1002
E +K+L ++ ++K S K +++F E
Sbjct: 1902 QAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1933
Score = 35.5 bits (78), Expect = 1.2
Identities = 63/311 (20%), Positives = 132/311 (42%), Gaps = 29/311 (9%)
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDL---IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
A+ E +E E + + DL ++A +A E + + +++ K K
Sbjct: 911 ALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEG-KVK 969
Query: 865 NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD---NLCL 921
+ +E +E N L +++++ + L K ID LK +AK E K+ ++ NL
Sbjct: 970 ELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTE 1029
Query: 922 RKAQTD--ITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKK 979
A D + K+ L E +++ L + ++ + + L + K + +L+
Sbjct: 1030 EMAALDESVARLTKEKKALQE----AHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLEC 1085
Query: 980 SLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE----- 1034
SL E EK L D E+ R+ +L +T+ D + L++ L + E
Sbjct: 1086 SL-----EQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLS 1140
Query: 1035 -KMENINMIIRELWRKI----YRGNDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEI 1089
++E+ ++ ++ +KI R +++ E++ E E+++ + + +
Sbjct: 1141 LRVEDEQLLGAQMQKKIKELQARAEELEE-ELEAERAARARVEKQRAEAARELEELSERL 1199
Query: 1090 DMRGRCSAGQK 1100
+ G SAGQ+
Sbjct: 1200 EEAGGASAGQR 1210
>AL132825-6|CAI43047.2| 1983|Homo sapiens myosin, heavy chain 7B,
cardiac muscle, beta protein.
Length = 1983
Score = 53.6 bits (123), Expect = 4e-06
Identities = 111/514 (21%), Positives = 216/514 (42%), Gaps = 50/514 (9%)
Query: 610 EKVTEDLQRASAK-KDEILSMKS-LNE-KITTLK-DTEIPQLEKRIVDVDTQIKTLNETV 665
E+V DL K +DE +K +++ K+T K + E E ++ ++ ++ L+E+V
Sbjct: 979 EEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESV 1038
Query: 666 EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVA 725
+T E + +Q GD+ + + +TK +++Q D+ E +L+
Sbjct: 1039 ARLTK---EKKALQEAHQQALGDLQAEE---DRVSALTKAKLRLEQQVEDL--ECSLEQE 1090
Query: 726 TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDI---- 781
++D ++ L +K TQ+ + + Q L EK K EL +V+D
Sbjct: 1091 KKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLG 1150
Query: 782 VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYI 841
+++ K+LQ+ A +E K++ EA E+ + L EAG A
Sbjct: 1151 AQMQKKIKELQARAEELEEELEAERAARARVE---KQRAEAARELEELSERLEEAGGASA 1207
Query: 842 A------KVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLT 895
K E +++ E + V K E +L E+ + RQ L
Sbjct: 1208 GQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLE 1267
Query: 896 KKIDTLKDEI----AKQEVYKR--DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEE 949
K+ L+ E+ A E R + LC R + ++ + + +EL +L + +
Sbjct: 1268 KEKSELRMEVDDLAANVETLTRAKASAEKLC-RTYEDQLSEAKIKVEELQRQLADASTQR 1326
Query: 950 LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHV 1009
++ + ++L ++K EC +S+L + K + + L + +E++ + K H
Sbjct: 1327 -GRLQTESGELSRLLEEK-EC--LISQLSRG-KALAAQSLEELRRQLEEESKAKSALAHA 1381
Query: 1010 TKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGN 1066
+A+ D +RE + E R + N + + WR Y + I +TE
Sbjct: 1382 VQALRHDCDLLREQHEEEAEAQAELQR-LLSKANAEVAQ-WRSKYEADAIQ----RTE-- 1433
Query: 1067 LTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQK 1100
+E ++K R+ +++ GVE +CS+ +K
Sbjct: 1434 -ELEEAKKKLALRLQEAEEGVEA-ANAKCSSLEK 1465
Score = 43.6 bits (98), Expect = 0.004
Identities = 84/425 (19%), Positives = 169/425 (39%), Gaps = 27/425 (6%)
Query: 617 QRASAKKDEI-LSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
Q+ +K E+ + + L + TL + EK + Q+ VEE+ L +
Sbjct: 1264 QKLEKEKSELRMEVDDLAANVETLTRAKA-SAEKLCRTYEDQLSEAKIKVEELQRQLADA 1322
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT--LDVATAKQVDFK 733
+ + G+ L R ++E + + + K E+ L+ + +
Sbjct: 1323 STQRGRLQTESGE---LSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALA 1379
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKK-----VQDIVNLEESK 788
+ LR+ +++ + L +KA E+ + K +Q LEE+K
Sbjct: 1380 HAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAK 1439
Query: 789 KQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAF 848
K+L + LE K K+ +TE +L A SA A +
Sbjct: 1440 KKLALRLQEAEEGVEAANAKCSSLE---KAKLRLQTESEDVTLELERATSAAAALDKKQR 1496
Query: 849 NKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQ 908
+ ++L E ++ +++ + RE+E Q + L + ++ + + ++TLK E
Sbjct: 1497 HLERAL--EERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNL 1554
Query: 909 EVYKRDLDDNLCLR-KAQTDITNWQKQDDELNEKLNGINKE-----ELNEKESLIIKQTK 962
+ DL D + L K+ ++ +K + ++ +E EL E ++L I Q +
Sbjct: 1555 QEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRI-QLE 1613
Query: 963 LFQQKAECTGALSELKKSLKGFRNELEK---SLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
L Q KAE L+E + R ++ SL ++ + R + L + K ++ D+ +
Sbjct: 1614 LSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLND 1673
Query: 1020 YAVAL 1024
+ L
Sbjct: 1674 LELQL 1678
Score = 37.5 bits (83), Expect = 0.29
Identities = 75/392 (19%), Positives = 156/392 (39%), Gaps = 29/392 (7%)
Query: 630 KSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDM 689
K+L E+I+ L D ++ K I +++ K L EI +L E E + +
Sbjct: 1552 KNLQEEISDLTD-QVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEET---KT 1607
Query: 690 PMLDRYIQEIKT-VTKKFEAVKEQCGDVDSEMTLDVATAK-QVDFKQKISTLRNRVKTTQ 747
+ + ++K V +K E+C ++ V + + +D + + RN +
Sbjct: 1608 LRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRA---RNEALRLK 1664
Query: 748 KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXX 807
KK+ L+ T+ E + +Q + E++ + +
Sbjct: 1665 KKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALE 1724
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK--- 864
L A E++ A E R+R L E + + N + S + + KKK
Sbjct: 1725 RRASLLAAELEELRAALEQGERSRRLAEQE---LLEATERLNLLHSQNTGLLNQKKKLEA 1781
Query: 865 ---NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCL 921
+ E+E+ + + EK K+ +TD ++ +++ +D A E K+ L+ +
Sbjct: 1782 DLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRE 1841
Query: 922 RKA------QTDITNWQKQDDELNEKLNGINKE--ELNEKESLIIKQTKLFQQKA-ECTG 972
+A Q + +KQ +L K+ + E +K + +K + +++ E
Sbjct: 1842 LQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAY 1901
Query: 973 ALSELKKSLKGFRNELEK--SLSKDIEKKFRE 1002
E +K+L ++ ++K S K +++F E
Sbjct: 1902 QAEEDRKNLARMQDLVDKLQSKVKSYKRQFEE 1933
Score = 35.5 bits (78), Expect = 1.2
Identities = 63/311 (20%), Positives = 132/311 (42%), Gaps = 29/311 (9%)
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDL---IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKK 864
A+ E +E E + + DL ++A +A E + + +++ K K
Sbjct: 911 ALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEG-KVK 969
Query: 865 NVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD---NLCL 921
+ +E +E N L +++++ + L K ID LK +AK E K+ ++ NL
Sbjct: 970 ELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQATENKVKNLTE 1029
Query: 922 RKAQTD--ITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKK 979
A D + K+ L E +++ L + ++ + + L + K + +L+
Sbjct: 1030 EMAALDESVARLTKEKKALQE----AHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLEC 1085
Query: 980 SLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHRE----- 1034
SL E EK L D E+ R+ +L +T+ D + L++ L + E
Sbjct: 1086 SL-----EQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLS 1140
Query: 1035 -KMENINMIIRELWRKI----YRGNDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEI 1089
++E+ ++ ++ +KI R +++ E++ E E+++ + + +
Sbjct: 1141 LRVEDEQLLGAQMQKKIKELQARAEELEE-ELEAERAARARVEKQRAEAARELEELSERL 1199
Query: 1090 DMRGRCSAGQK 1100
+ G SAGQ+
Sbjct: 1200 EEAGGASAGQR 1210
>AK027863-1|BAB55415.1| 612|Homo sapiens protein ( Homo sapiens cDNA
FLJ14957 fis, clone PLACE4000009, weakly similar to
MYOSIN HEAVY CHAIN, NONMUSCLE TYPE B. ).
Length = 612
Score = 53.6 bits (123), Expect = 4e-06
Identities = 61/274 (22%), Positives = 128/274 (46%), Gaps = 25/274 (9%)
Query: 740 RNRVKTTQKKLNAHNKKLQTLYEKKTKAK----EELLNTQKKVQDIVNLEESKKQLQSDC 795
+ ++ Q +L+ + +L + + + K EELL ++ +QD++ +E ++ L
Sbjct: 7 QTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDL---- 62
Query: 796 XXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAG-SAYIAKVEVAFNKVKSL 854
+T L+ ALKE++ + + + + ++ +A A VE A V+ L
Sbjct: 63 ------LRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVL 116
Query: 855 DAEIQQHKKKNVPREM--EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLK-DEIAKQEVY 911
+ ++ EM + +QE N+KL + +++ L ++I+ LK DE +E
Sbjct: 117 ASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETL 176
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECT 971
K+ + +R+ + + + +K++ E + + EL + + + T+ +Q +E
Sbjct: 177 KKYEGE---IRQLEEALVHVRKEEKEAVSARRAL-ENELEAAQGNLSQTTQEQKQLSEKL 232
Query: 972 GALSELKKSLKGFRNELEKS---LSKDIEKKFRE 1002
SE K+ L+ +NE+E L K IEK +E
Sbjct: 233 KEESEQKEQLRRLKNEMENERWHLGKTIEKLQKE 266
Score = 44.8 bits (101), Expect = 0.002
Identities = 80/400 (20%), Positives = 174/400 (43%), Gaps = 32/400 (8%)
Query: 614 EDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLI 673
EDL R ++ E+ ++K ++ + D E+ +L+++ D +++ L E+VEE T ++
Sbjct: 60 EDLLRK--RERELTALKGALKEEVSSHDQEMDKLKEQY---DAELQALRESVEEATKNVE 114
Query: 674 EPEQKMTTAKQIHGDMPMLDRYIQE----IKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ 729
+ T++Q M + +QE ++ +++ E Q ++ D A AK+
Sbjct: 115 VLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKE 174
Query: 730 V--DFKQKISTLRN---RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL 784
++ +I L V+ +K+ + + L+ E + QK++ + +
Sbjct: 175 TLKKYEGEIRQLEEALVHVRKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKE 234
Query: 785 E-ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEA-KTEVVRRNRDL---IEAGSA 839
E E K+QL+ I L+ + + +EA +T + L E
Sbjct: 235 ESEQKEQLRRLKNEMENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRR 294
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKID 899
+A+++ K K+L+AE + + M ++E Q + +T RQ+L + +
Sbjct: 295 ELAEMQRQL-KEKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRAQDEALTKRQLLEQTLK 353
Query: 900 TLKDEIAKQEVYKRD-------LDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
L+ E+ + K D ++D + + + ++ + D L E+++ ++E++ +
Sbjct: 354 DLEYELEAKSHLKDDRSRLVKQMEDK--VSQLEMELEEERNNSDLLTERISR-SREQMEQ 410
Query: 953 KESLIIKQTKLFQQKAECTG-ALSELKKSLKGFRNELEKS 991
+ ++ Q + +Q EC +L K LK LE S
Sbjct: 411 LRNELL-QERAARQDLECDKISLERQNKDLKSRIIHLEGS 449
Score = 38.7 bits (86), Expect = 0.12
Identities = 83/477 (17%), Positives = 193/477 (40%), Gaps = 33/477 (6%)
Query: 392 NIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEK-EMIEENLKTKEKQLIV 450
++EE + + EQ+ ++ LQ++ KL+ + E +E + ++Q+
Sbjct: 105 SVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQEENEKLQGRSEELERRVAQLQRQIED 164
Query: 451 LKN---KHKTALMELLGNVPEKDFA-VTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAE 506
LK K K L + G + + + A V + K E E + E
Sbjct: 165 LKGDEAKAKETLKKYEGEIRQLEEALVHVRKEEKEAVSARRALENELEAAQGNLSQTTQE 224
Query: 507 RKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQ-NVLQSSMFII 565
+K + E L E SE + ++ + + L K T+EKLQ E +++++S
Sbjct: 225 QKQLSEKLKEE-SEQKEQLRRLKNEMENERWH--LGK---TIEKLQKEMADIVEASRTST 278
Query: 566 NKYKGQL---KDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
+ + QL K+ + L + + E M + + + E+L+
Sbjct: 279 LELQNQLDEYKEKNRRELAEMQRQLK-EKTLEAEKSRLTAMKMQDGMRLMEEELRDYQRA 337
Query: 623 KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTA 682
+DE L+ + L E+ TLKD E +LE + D + + + + ++++ +E E++ +
Sbjct: 338 QDEALTKRQLLEQ--TLKDLEY-ELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNS 394
Query: 683 KQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNR 742
+ + +++++ E ++E+ D E ++ +++ L++R
Sbjct: 395 DLLTERISRSREQMEQLRN-----ELLQERAARQDLE-------CDKISLERQNKDLKSR 442
Query: 743 VKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXX 802
+ + + + L E + E+ L ++++ D NL+ S ++L+
Sbjct: 443 IIHLEGSYRSSKEGLVVQMEARIAELEDRLESEER--DRANLQLSNRRLERKVKELVMQV 500
Query: 803 XXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQ 859
++T + L +++A V + I+ + K++ + ++ +Q
Sbjct: 501 DDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQ 557
Score = 35.1 bits (77), Expect = 1.5
Identities = 64/305 (20%), Positives = 112/305 (36%), Gaps = 21/305 (6%)
Query: 160 HQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQ 219
H E S E ++ +E+ A + L K+ R+D L+ E T +K
Sbjct: 21 HDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEGREDL---LRKRERELTALKGAL 77
Query: 220 KELEDSYKKNTSFNKEE---EKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
KE S+ + KE+ E A +S E N +L N + D+ ++ K
Sbjct: 78 KEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEM--RVK 135
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHT 336
+ + EN +EE E + ++E LK D +++A E KK +G + +
Sbjct: 136 LLQEENEKLQGRSEELERRVAQLQRQIEDLKGD----EAKAKETLKKYEGEIRQLEEALV 191
Query: 337 QXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEEC 396
+ +Q+ +Q N E
Sbjct: 192 HVRKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKN--EM 249
Query: 397 QQEINEDEKAVEQYEQEMDELSQ----KITKLQKQTAKLKEK---EMIEENLKTKEKQLI 449
+ E K +E+ ++EM ++ + +LQ Q + KEK E+ E + KEK L
Sbjct: 250 ENERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRRELAEMQRQLKEKTLE 309
Query: 450 VLKNK 454
K++
Sbjct: 310 AEKSR 314
>AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein.
Length = 1978
Score = 53.6 bits (123), Expect = 4e-06
Identities = 194/1014 (19%), Positives = 408/1014 (40%), Gaps = 94/1014 (9%)
Query: 71 KVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKD 130
K+N EV+ + ++ D +L +++ AK++ Q++ + + E +
Sbjct: 447 KLNNEYEVIKSTATRDISL-DSELH---DLRLNLEAKEQELNQSISEKETLIAEIEELDR 502
Query: 131 VSSRCADLDILMHEELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDC 190
+ IL+ +L + +S++ ++D + DE K+V + D+ D K D
Sbjct: 503 QNQEATKHMILIKAQLSKQQNEGDSIISKLKQDLN---DEKKRVHQLEDDKMDITKELD- 558
Query: 191 LDRLKKIRKDYAQN-LKLL-ENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEI 248
+ + I+ + A N L L + V+ +L S + N S KE ++ NE
Sbjct: 559 VQFVLLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEE 618
Query: 249 EYNKFI--LLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESL 306
E ++ L++S NQ+ + +++ + AE+ N+ + + E N E ++ +
Sbjct: 619 ELSRIRNELMQSLNQDSNSNFKDTLLKERE-AEVRNLKQNLSELEQLN------ENLKKV 671
Query: 307 KSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQS 366
D K++ + + + ++EC +G+ Q ++ A +
Sbjct: 672 AFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKR 731
Query: 367 XXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQK 426
A N LN Q E K ++ + E+ EL + I Q
Sbjct: 732 LLEEANKYEKTIEELS---NARN-LNTSALQLEHEHLIKLNQKKDMEIAELKKNIE--QM 785
Query: 427 QTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVR-NE 485
T + K+++ +L+ ++KQL L NK K +E L K ++K+ +R NE
Sbjct: 786 DTDHKETKDVLSSSLE-EQKQLTQLINK-KEIFIEKLKERSSK-LQEELDKYSQALRKNE 842
Query: 486 VXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELTK----AEDKIYKACGTQPYDVTL 541
+ ++ E H++E L R E ++ A+ K + +V
Sbjct: 843 ILRQTIEEKDRSLGS--MKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEV-- 898
Query: 542 SKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXX 601
S+ T E L++E Q + N+ K QL + E +
Sbjct: 899 SQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSL----------QEQKKEMDEFRYQHE 948
Query: 602 XMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDV--DTQIK 659
MN Q K +EI S++ E+I T E ++ D+ +T+++
Sbjct: 949 QMNAT--------HTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQ 1000
Query: 660 TLN--ETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAV-KEQCGDV 716
+LN E+ +S E E+ + K+ ++ +L+ ++ ++TK+ + + K++ G +
Sbjct: 1001 SLNIENGSEKHDLSKAETERLVKGIKERELEIKLLN---EKNISLTKQIDQLSKDEVGKL 1057
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAH---NKKLQTLYEKKTKAKEELLN 773
+ + + + ++ V Q++L A+ +K+ + +KT+ L
Sbjct: 1058 TQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKT 1117
Query: 774 TQKKVQDIVNLEESKK-QLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
K+ DIV +E+ +LQ + + +E I+ + ++R
Sbjct: 1118 EYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDM------FRETIQNLSRIIREKDI 1171
Query: 833 LIEAGSAYIAKVEVAFNKVKSLDAE---IQQHKKKNVPREMEKIQEANDKLMEKQKQIMT 889
I+A S + +A + S E + ++ + + +E +K+++ K+ E ++Q+MT
Sbjct: 1172 EIDALSQKCQTL-LAVLQTSSTGNEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMT 1230
Query: 890 DRQVLTKKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKE 948
Q + + L++E+ + Q D D+N K Q D T + ++ KL +E
Sbjct: 1231 TVQNMQHESAQLQEELHQLQAQVLVDSDNN---SKLQVDYTGLIQSYEQNETKLKNFGQE 1287
Query: 949 ---------EL-NEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+L N K+ L+ K + Q + + + + L+ ++E+ S+ +++
Sbjct: 1288 LAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQ 1347
Query: 999 KFREKMYELHVTKAIDKDIREYAVALDKCL---MEFHREKMENINMIIRELWRK 1049
+ E L A + ++E L + E R++ E + I++L K
Sbjct: 1348 ELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEK 1401
Score = 50.8 bits (116), Expect = 3e-05
Identities = 78/391 (19%), Positives = 175/391 (44%), Gaps = 30/391 (7%)
Query: 607 GKLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
G +E+V Q S ++EI+ + SLN+ + +D +L+ RI ++ + L++ E
Sbjct: 382 GSVEEVFRLRQALSDAENEIMRLSSLNQDNSLAEDN--LKLKMRIEVLEKEKSLLSQEKE 439
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
E+ MSL++ + K LD + +++ EA +++ SE +A
Sbjct: 440 ELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRL---NLEAKEQELNQSISEKETLIAE 496
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
+++D + + +T + + +L+ + ++ +K K++L + +K+V LE+
Sbjct: 497 IEELDRQNQEAT--KHMILIKAQLSKQQNEGDSII---SKLKQDLNDEKKRVH---QLED 548
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
K + + A+ L + K+K+E K E + + + + I K +
Sbjct: 549 DKMDITKELDVQFVLLIQSEVALNDLHLT-KQKLEDKVENLVDQLNKSQESNVSIQKENL 607
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDK---LMEKQKQIMTDRQVLTKKIDTLKD 903
+ + E + + + + + +N K L E++ ++ +Q L+ +++ L +
Sbjct: 608 ELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLS-ELEQLNE 666
Query: 904 EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKL 963
+ K + ++ L L A D+ + +L E L G N +L+ +++ I++ K+
Sbjct: 667 NLKKVAFDVKMENEKLVL--ACEDVRH------QLEECLAGNN--QLSLEKNTIVETLKM 716
Query: 964 FQQKAECTGALSELKKSLKGFRNELEKSLSK 994
+K E L KK L N+ EK++ +
Sbjct: 717 --EKGEIEAELCWAKKRLLEEANKYEKTIEE 745
Score = 46.8 bits (106), Expect = 5e-04
Identities = 79/448 (17%), Positives = 199/448 (44%), Gaps = 44/448 (9%)
Query: 642 TEIPQLEKRIVDV-DTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGD-MPMLDRYIQEI 699
+EI +L+ I ++ + + +++ E+++ +QK+T + H + + + I+E+
Sbjct: 209 SEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEEL 268
Query: 700 KTVTKKFEA--VKEQCGDV-DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK 756
+ + ++ + ++ + + + T+ V ++V+ +K+ L +++K KKL++
Sbjct: 269 ENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAEND 328
Query: 757 LQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVAL 816
L + ++E LN +K+ + E + L+ +C +T E L
Sbjct: 329 RDIL-----RREQEQLNVEKR-----QIMEECENLKLECSKLQPSAVKQSDTMTEKERIL 378
Query: 817 KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEA 876
+ E V R R + I ++ + N+ SL + + K + +E +++
Sbjct: 379 AQS--GSVEEVFRLRQALSDAENEIMRLS-SLNQDNSLAEDNLKLKMR-----IEVLEKE 430
Query: 877 NDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDD 936
L ++++++ L + + +K + +L D LR N + ++
Sbjct: 431 KSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHD---LR------LNLEAKEQ 481
Query: 937 ELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
ELN+ ++ EKE+LI + +L +Q E T + +K L +NE + +SK +
Sbjct: 482 ELNQSIS--------EKETLIAEIEELDRQNQEATKHMILIKAQLSKQQNEGDSIISK-L 532
Query: 997 EKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDI 1056
++ ++ +H + DI + + + L+ + ++++ ++L K+ N +
Sbjct: 533 KQDLNDEKKRVHQLEDDKMDITK-ELDVQFVLLIQSEVALNDLHLTKQKLEDKV--ENLV 589
Query: 1057 DYIEIKTEGNLTVESERRKYDYRVVQSK 1084
D + E N++++ E + + Q++
Sbjct: 590 DQLNKSQESNVSIQKENLELKEHIRQNE 617
Score = 35.9 bits (79), Expect = 0.88
Identities = 61/331 (18%), Positives = 141/331 (42%), Gaps = 24/331 (7%)
Query: 730 VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESK 788
+ +Q+I+ L N V + ++ QT + T ++ + K+Q+I+ L++++
Sbjct: 168 ISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQ--SEICKLQNIIKELKQNR 225
Query: 789 KQ-LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
Q + +T + +E++ E + +L++ G + + +E
Sbjct: 226 SQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGV--IETD 283
Query: 848 FNKVKSLDAEIQ--QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEI 905
+K+ + IQ Q +K ++ME++++ + +K DR +L ++ + L +
Sbjct: 284 LSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQL--NV 341
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEK-----LNGINKEELNEKESLIIKQ 960
K+++ + + L K Q KQ D + EK +G +E +++L +
Sbjct: 342 EKRQIMEECENLKLECSKLQPSAV---KQSDTMTEKERILAQSGSVEEVFRLRQALSDAE 398
Query: 961 TKLFQ-QKAECTGALSE--LKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDI 1017
++ + +L+E LK ++ E EKSL +++ + + +L+ + K
Sbjct: 399 NEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKST 458
Query: 1018 REYAVALDKCLMEFH---REKMENINMIIRE 1045
++LD L + K + +N I E
Sbjct: 459 ATRDISLDSELHDLRLNLEAKEQELNQSISE 489
Score = 33.5 bits (73), Expect = 4.7
Identities = 51/251 (20%), Positives = 102/251 (40%), Gaps = 27/251 (10%)
Query: 218 KQKELEDSYKKNTSFNKEEEKIANE--KSSNEIEYNKFILLESQN---QEKIDKRNEQIV 272
KQK++E NT+ E +++ ++ +S+ E+E + LLES++ +E + + +
Sbjct: 1554 KQKQME-----NTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAK 1608
Query: 273 ETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDECR 332
K+ +E V ++ ENA+ +VESL+ V Q DE + C
Sbjct: 1609 LRKKVTVLEEKL-VSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALRF------CL 1661
Query: 333 SGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELN 392
SG + + SA K ++
Sbjct: 1662 SGTVKQYRLSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGK----VIS 1717
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
++EC E N + + +++D ++I +L++Q E+ +E L +K+L+ L
Sbjct: 1718 LQECLDEANAALDSASRLTEQLDVKEEQIEELKRQ------NELRQEMLDDVQKKLMSLA 1771
Query: 453 NKHKTALMELL 463
N + + ++L
Sbjct: 1772 NSSEGKVDKVL 1782
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 53.2 bits (122), Expect = 5e-06
Identities = 113/562 (20%), Positives = 243/562 (43%), Gaps = 54/562 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 913 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 656 TQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
++K L E + +EI L + ++ + A Q D + ++ T+TK +++Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLTKAKVKLEQQ 1030
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D++ +L+ ++D ++ L +K TQ+ + Q L E+ K EL
Sbjct: 1031 VDDLEG--SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN 1088
Query: 773 NTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+++D L++ K+LQ+ A +E K + + E+
Sbjct: 1089 ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE---KLRSDLSRELEE 1145
Query: 829 RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+ L EAG A V++ NK + +AE Q+ ++++ + + L +K +
Sbjct: 1146 ISERLEEAGGA--TSVQIEMNKKR--EAEFQK-MRRDLEEATLQHEATAAALRKKHADSV 1200
Query: 889 TDRQVLTKKIDTLKDEIAKQE-VYKRDLDD---NL-CLRKAQTDITNW-QKQDDELNEKL 942
+ + +K ++ K++ +K +LDD N+ + KA+ ++ + +D++NE
Sbjct: 1201 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR 1260
Query: 943 NGINKEE------LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
+ + + +++ L + +L +Q E +S+L + + +LE L + +
Sbjct: 1261 SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE-DLKRQL 1319
Query: 997 EKKFREKMYELHVTKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRG 1053
E++ + K H ++ D +RE + E R + N + + WR Y
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR-VLSKANSEVAQ-WRTKY-- 1375
Query: 1054 NDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACL--IIRLAL 1111
+ D I+ +TE +E ++K R+ +++ VE + +CS+ +K L I +
Sbjct: 1376 -ETDAIQ-RTE---ELEEAKKKLAQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLM 1429
Query: 1112 AETFSSRFGILALDEPTTNLDQ 1133
+ S ALD+ N D+
Sbjct: 1430 VDVERSNAAAAALDKKQRNFDK 1451
Score = 52.4 bits (120), Expect = 9e-06
Identities = 160/845 (18%), Positives = 347/845 (41%), Gaps = 83/845 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ + +++K+R D ++ L+ + E A ++E + K+ F K
Sbjct: 1116 EELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1173
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K + +V
Sbjct: 1174 MRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232
Query: 288 TNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXX 346
+N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 1233 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLD 1292
Query: 347 XXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA 406
+T Q +A+N L Q ++ +
Sbjct: 1293 EKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARHDCDLL 1343
Query: 407 VEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E L K K L E
Sbjct: 1344 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAE 1401
Query: 464 GNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V + + + K + ++NE+ L+ ++++ + L E + +
Sbjct: 1402 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 1461
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPL 580
+++ ++ + Q +LS T + KL+ N + S+ + +K + K+ L
Sbjct: 1462 ESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 581 CNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLN 633
+ G ++ E M + LE+ L+ K + E +K+
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD+ ++
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGDLNEME 1626
Query: 694 RYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + + + D+++ LD A D K+ I+ + R Q +L
Sbjct: 1627 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1686
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
++ + A++EL+ T ++VQ + +L KK++ +D
Sbjct: 1687 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ-------- 1738
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP 867
T +E A++E A+ + + D +A +A+ K + A +++ KKN+
Sbjct: 1739 --TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-MKKNME 1787
Query: 868 REMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
+ ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +RK++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGMRKSER 1845
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
I Q +E ++ N + ++L +K L +K K ++AE A + L K K ++
Sbjct: 1846 RIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFRK-VQH 1901
Query: 987 ELEKS 991
EL+++
Sbjct: 1902 ELDEA 1906
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 53.2 bits (122), Expect = 5e-06
Identities = 113/562 (20%), Positives = 243/562 (43%), Gaps = 54/562 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 913 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 656 TQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
++K L E + +EI L + ++ + A Q D + ++ T+TK +++Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLTKAKVKLEQQ 1030
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D++ +L+ ++D ++ L +K TQ+ + Q L E+ K EL
Sbjct: 1031 VDDLEG--SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN 1088
Query: 773 NTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+++D L++ K+LQ+ A +E K + + E+
Sbjct: 1089 ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE---KLRSDLSRELEE 1145
Query: 829 RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+ L EAG A V++ NK + +AE Q+ ++++ + + L +K +
Sbjct: 1146 ISERLEEAGGA--TSVQIEMNKKR--EAEFQK-MRRDLEEATLQHEATAAALRKKHADSV 1200
Query: 889 TDRQVLTKKIDTLKDEIAKQE-VYKRDLDD---NL-CLRKAQTDITNW-QKQDDELNEKL 942
+ + +K ++ K++ +K +LDD N+ + KA+ ++ + +D++NE
Sbjct: 1201 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR 1260
Query: 943 NGINKEE------LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
+ + + +++ L + +L +Q E +S+L + + +LE L + +
Sbjct: 1261 SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE-DLKRQL 1319
Query: 997 EKKFREKMYELHVTKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRG 1053
E++ + K H ++ D +RE + E R + N + + WR Y
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR-VLSKANSEVAQ-WRTKY-- 1375
Query: 1054 NDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACL--IIRLAL 1111
+ D I+ +TE +E ++K R+ +++ VE + +CS+ +K L I +
Sbjct: 1376 -ETDAIQ-RTE---ELEEAKKKLAQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLM 1429
Query: 1112 AETFSSRFGILALDEPTTNLDQ 1133
+ S ALD+ N D+
Sbjct: 1430 VDVERSNAAAAALDKKQRNFDK 1451
Score = 52.4 bits (120), Expect = 9e-06
Identities = 160/845 (18%), Positives = 347/845 (41%), Gaps = 83/845 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ + +++K+R D ++ L+ + E A ++E + K+ F K
Sbjct: 1116 EELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1173
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K + +V
Sbjct: 1174 MRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232
Query: 288 TNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXX 346
+N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 1233 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLD 1292
Query: 347 XXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA 406
+T Q +A+N L Q ++ +
Sbjct: 1293 EKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARHDCDLL 1343
Query: 407 VEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E L K K L E
Sbjct: 1344 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAE 1401
Query: 464 GNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V + + + K + ++NE+ L+ ++++ + L E + +
Sbjct: 1402 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 1461
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPL 580
+++ ++ + Q +LS T + KL+ N + S+ + +K + K+ L
Sbjct: 1462 ESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 581 CNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLN 633
+ G ++ E M + LE+ L+ K + E +K+
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD+ ++
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGDLNEME 1626
Query: 694 RYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + + + D+++ LD A D K+ I+ + R Q +L
Sbjct: 1627 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1686
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
++ + A++EL+ T ++VQ + +L KK++ +D
Sbjct: 1687 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ-------- 1738
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP 867
T +E A++E A+ + + D +A +A+ K + A +++ KKN+
Sbjct: 1739 --TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-MKKNME 1787
Query: 868 REMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
+ ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +RK++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGMRKSER 1845
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
I Q +E ++ N + ++L +K L +K K ++AE A + L K K ++
Sbjct: 1846 RIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFRK-VQH 1901
Query: 987 ELEKS 991
EL+++
Sbjct: 1902 ELDEA 1906
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 53.2 bits (122), Expect = 5e-06
Identities = 113/562 (20%), Positives = 243/562 (43%), Gaps = 54/562 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 913 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 656 TQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
++K L E + +EI L + ++ + A Q D + ++ T+TK +++Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLTKAKVKLEQQ 1030
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D++ +L+ ++D ++ L +K TQ+ + Q L E+ K EL
Sbjct: 1031 VDDLEG--SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN 1088
Query: 773 NTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+++D L++ K+LQ+ A +E K + + E+
Sbjct: 1089 ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE---KLRSDLSRELEE 1145
Query: 829 RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+ L EAG A V++ NK + +AE Q+ ++++ + + L +K +
Sbjct: 1146 ISERLEEAGGA--TSVQIEMNKKR--EAEFQK-MRRDLEEATLQHEATAAALRKKHADSV 1200
Query: 889 TDRQVLTKKIDTLKDEIAKQE-VYKRDLDD---NL-CLRKAQTDITNW-QKQDDELNEKL 942
+ + +K ++ K++ +K +LDD N+ + KA+ ++ + +D++NE
Sbjct: 1201 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR 1260
Query: 943 NGINKEE------LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
+ + + +++ L + +L +Q E +S+L + + +LE L + +
Sbjct: 1261 SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE-DLKRQL 1319
Query: 997 EKKFREKMYELHVTKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRG 1053
E++ + K H ++ D +RE + E R + N + + WR Y
Sbjct: 1320 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR-VLSKANSEVAQ-WRTKY-- 1375
Query: 1054 NDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACL--IIRLAL 1111
+ D I+ +TE +E ++K R+ +++ VE + +CS+ +K L I +
Sbjct: 1376 -ETDAIQ-RTE---ELEEAKKKLAQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLM 1429
Query: 1112 AETFSSRFGILALDEPTTNLDQ 1133
+ S ALD+ N D+
Sbjct: 1430 VDVERSNAAAAALDKKQRNFDK 1451
Score = 52.4 bits (120), Expect = 9e-06
Identities = 160/845 (18%), Positives = 347/845 (41%), Gaps = 83/845 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ + +++K+R D ++ L+ + E A ++E + K+ F K
Sbjct: 1116 EELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 1173
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K + +V
Sbjct: 1174 MRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232
Query: 288 TNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXX 346
+N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 1233 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLD 1292
Query: 347 XXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA 406
+T Q +A+N L Q ++ +
Sbjct: 1293 EKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARHDCDLL 1343
Query: 407 VEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E L K K L E
Sbjct: 1344 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAE 1401
Query: 464 GNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V + + + K + ++NE+ L+ ++++ + L E + +
Sbjct: 1402 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 1461
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPL 580
+++ ++ + Q +LS T + KL+ N + S+ + +K + K+ L
Sbjct: 1462 ESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 581 CNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLN 633
+ G ++ E M + LE+ L+ K + E +K+
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD+ ++
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGDLNEME 1626
Query: 694 RYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + + + D+++ LD A D K+ I+ + R Q +L
Sbjct: 1627 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1686
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
++ + A++EL+ T ++VQ + +L KK++ +D
Sbjct: 1687 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ-------- 1738
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP 867
T +E A++E A+ + + D +A +A+ K + A +++ KKN+
Sbjct: 1739 --TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-MKKNME 1787
Query: 868 REMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
+ ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +RK++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGMRKSER 1845
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
I Q +E ++ N + ++L +K L +K K ++AE A + L K K ++
Sbjct: 1846 RIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFRK-VQH 1901
Query: 987 ELEKS 991
EL+++
Sbjct: 1902 ELDEA 1906
>BC090932-1|AAH90932.1| 1377|Homo sapiens NIN protein protein.
Length = 1377
Score = 53.2 bits (122), Expect = 5e-06
Identities = 103/565 (18%), Positives = 220/565 (38%), Gaps = 21/565 (3%)
Query: 388 ENELNIEECQQEINE-DEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKE- 445
E ++ ++ Q+ + + E E+++ +L +I +LQ Q A LKE E + +E
Sbjct: 642 ETVVSCKKAQENMKQRHENETHTLEKQISDLKNEIAELQGQAAVLKEAHH-EATCRHEEE 700
Query: 446 -KQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLE 504
KQL V + KT L E L E + + + + E +
Sbjct: 701 KKQLQVKLEEEKTHLQEKLRLQHEMELKARLTQAQASFEREREGLQSSAWTEEKVRGLTQ 760
Query: 505 AERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFI 564
+ +E L + T ++++ K + + L + EKLQ E ++L++ +
Sbjct: 761 ELEQFHQEQLTSLVEKHTLEKEELRKEL-LEKHQRELQEGRYESEKLQQENSILRNEITT 819
Query: 565 INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD 624
+N+ N N E + + L+K +L+ + + D
Sbjct: 820 LNEEDS--ISNLKLGTLNGSQEEMWQKTETVKQENAAVQKMVENLKKQISELKIKNQQLD 877
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDV--DTQIKTLNETVEEITMSLIEPEQKMTTA 682
L L++K + ++ +L +R+ ++ + + N +EE ++++
Sbjct: 878 --LENTELSQK-NSQNQEKLQELNQRLTEMLCQKEKEPGNSALEEREQEKFNLKEELERC 934
Query: 683 K-QIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRN 741
K Q + L+ + E+K T + D +M DF+QKIS++ +
Sbjct: 935 KVQSSTLVSSLEAELSEVKIQTHIVQQENHLLKDELEKMKQLHRCPDLSDFQQKISSVLS 994
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAK--EELLNTQKKVQDIVNLEESKKQLQSDCXXXX 799
+ K+ A +++L + +K K+ E + T K+ Q + E L+S
Sbjct: 995 YNEKLLKEKEALSEELNSCVDKLAKSSLLEHRIATMKQEQK--SWEHQSASLKSQLVASQ 1052
Query: 800 XXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQ 859
+ + + + ++++ V ++ ++ ++ + K ++ KS EI
Sbjct: 1053 EKVQNLEDTVQNVNLQM-SRMKSDLRVTQQEKEALKQEVMSLHK-QLQNAGGKSWAPEIA 1110
Query: 860 QHKKKNVPREMEKIQEANDKLMEKQKQIM-TDRQVLTKKIDTLKDEIAKQEVYKRDLDDN 918
H ++ + D LM +++Q++ + + L + K E+ R L+ N
Sbjct: 1111 THPSGLHNQQKRLSWDKLDHLMNEEQQLLWQENERLQTMVQNTKAELTHSREKVRQLESN 1170
Query: 919 LCLRKAQTDITNWQKQDDELNEKLN 943
L L K Q + + EKL+
Sbjct: 1171 L-LPKHQKHLNPSGTMNPTEQEKLS 1194
>AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1116
Score = 53.2 bits (122), Expect = 5e-06
Identities = 87/488 (17%), Positives = 206/488 (42%), Gaps = 35/488 (7%)
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGT-----QPYDVTLSKYTTTVEKLQDEQNV 557
LE + I+ L + + EL K ++++ K Q + ++ K T +++++ N+
Sbjct: 9 LELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELETSIKKIITQNQRIKELINI 68
Query: 558 LQSSMFIINKYKG--QLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP-GKLEKVTE 614
+ IN+++ L +N+ CN + S + VP K+
Sbjct: 69 IDQKEDTINEFQNLKSLMENTF--KCNDKADTSS-LIINNKLICNETVEVPKDSKSKICS 125
Query: 615 DLQRASA---KKDEILSMK-SLNEKITTLKDTE-IPQLEKRIVDVDTQIKTLNETVEEIT 669
+ +R + ++DE + K S++ +D + ++ I +++ I+ L E E +
Sbjct: 126 ERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIE-DIRVLQENNEGLR 184
Query: 670 MSLIEPEQKMTTAKQIHGDM-PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT-- 726
L+ E ++ K+ ++ + + QE+ KK + ++ + S + +A
Sbjct: 185 AFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELH 244
Query: 727 ---AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
+K + ++KI L N ++T + + + +++ ++ K + + +Q D++N
Sbjct: 245 VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLN 304
Query: 784 L--------EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN-RDLI 834
L E++ Q D E + + E + ++++
Sbjct: 305 LRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIV 364
Query: 835 EAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVL 894
+A S ++E +++ L AE++ +K +N + ++ + +D L EK+ I ++ L
Sbjct: 365 KASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEEL 424
Query: 895 TKKIDTLKDEIAKQEVYKR---DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELN 951
+K TL +I KR +L + KA+ + ++ + ++++
Sbjct: 425 QEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDIL 484
Query: 952 EKESLIIK 959
EKES+I+K
Sbjct: 485 EKESIILK 492
Score = 51.6 bits (118), Expect = 2e-05
Identities = 119/655 (18%), Positives = 257/655 (39%), Gaps = 30/655 (4%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIV 450
+N E QQ+ +K + E +K +++ A++++ +++EN + L+
Sbjct: 130 VNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLT 189
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
++N+ K E E + + + E + + + H+
Sbjct: 190 IENELKNEKEEKA----ELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHV 245
Query: 511 RESLNERRSE-LTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++S N+ + E + K ++I A + +V+ K T K+ DE L S I N
Sbjct: 246 QKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHT--KI-DELRTLDSVSQISNIDL 302
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
L+D L N E+ ++ K ++ E + S
Sbjct: 303 LNLRD-----LSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIW 357
Query: 630 KSLNE--KITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG 687
+ E K ++ K +I +LE++I + ++K + E + E + + K+
Sbjct: 358 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKD--ENNRLKEKEHKNQDDLLKEKET 415
Query: 688 DMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQ 747
+ L +QE K VT + V+ + L T +K KI L + TQ
Sbjct: 416 LIQQLKEELQE-KNVTLDVQIQHV----VEGKRALSELTQGVTCYKAKIKELET-ILETQ 469
Query: 748 KKLNAHNKKL-QTLYEKKT---KAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXX 803
K +H+ KL Q + EK++ K + L Q+ +QD V + +
Sbjct: 470 KVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLT 529
Query: 804 XXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK 863
+ L +E+ E + + ++ + A SA ++ + + A++++ K
Sbjct: 530 NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE-KL 588
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
+ ++++++Q+ + ++ K + L KK + E+ ++ + L + L +K
Sbjct: 589 TDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQK 648
Query: 924 AQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ I +++ +LN EK+ + L E+E ++Q ++ + K E L+ +
Sbjct: 649 VEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKW 708
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM 1036
K N+LE ++ K+ L + +++E + ++ EKM
Sbjct: 709 KEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKM 763
Score = 46.4 bits (105), Expect = 6e-04
Identities = 90/431 (20%), Positives = 184/431 (42%), Gaps = 36/431 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++E++ + +++ A E+ K N + LK+ E + + + +T I+ L E ++E
Sbjct: 373 QIEELEQQIEKLQA---EVKGYKDENNR---LKEKEHKNQDDLLKEKETLIQQLKEELQE 426
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++L Q + K+ ++ + Y +IK + E K + +++ D+
Sbjct: 427 KNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSH-SAKLEQDILE 485
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL-- 784
+ + K L +K Q+ L K + L K+ K KEE+ +QD+ +L
Sbjct: 486 KESIILK-----LERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQ 540
Query: 785 --EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE ++ + + L+ L+ K E ++ + D +
Sbjct: 541 LKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQK 600
Query: 843 KVEVAFNKVKSLDAEIQQ-HKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+V V ++ K L +I + KKKN +E++ Q +L E+ + + + +
Sbjct: 601 EVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVE-EAIQQYERA 659
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--EELNE-KESLI 957
KD K+++ + D+ L + QT + +QD L KL + + EL + KE
Sbjct: 660 CKDLNVKEKIIE-DMRMTL-EEQEQTQV----EQDQVLEAKLEEVERLATELEKWKEKCN 713
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK---DIEKKFREKMYELHVTKAID 1014
+TK Q+ + +++ L ++EL++S K D +K EKM + K +
Sbjct: 714 DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAE 773
Query: 1015 ----KDIREYA 1021
K++++YA
Sbjct: 774 NIRNKEMKKYA 784
>AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens cDNA:
FLJ21306 fis, clone COL02125. ).
Length = 696
Score = 53.2 bits (122), Expect = 5e-06
Identities = 119/655 (18%), Positives = 258/655 (39%), Gaps = 30/655 (4%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIV 450
+N E QQ+ +K + E +K +++ A++++ +++EN + L+
Sbjct: 45 VNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPSIAEIEDIRVLQENNEGLRAFLLT 104
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
++N+ K E E + + ++ E + + + H+
Sbjct: 105 IENELKNEKEEKA----ELNKQIVHSQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHV 160
Query: 511 RESLNERRSE-LTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++S N+ + E + K ++I A + +V+ K T K+ DE L S I N
Sbjct: 161 QKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHT--KI-DELRTLDSVSQISNIDL 217
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
L+D L N E+ ++ K ++ E + S
Sbjct: 218 LNLRD-----LSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIW 272
Query: 630 KSLNE--KITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG 687
+ E K ++ K +I +LE++I + ++K + E + E + + K+
Sbjct: 273 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKD--ENNRLKEREHKNQDDLLKEKET 330
Query: 688 DMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQ 747
+ L +QE K VT + V+ + L T +K KI L + TQ
Sbjct: 331 LIQQLKEELQE-KNVTLDVQIQHV----VEGKRALSELTQGVTCYKAKIKELET-ILETQ 384
Query: 748 KKLNAHNKKL-QTLYEKKT---KAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXX 803
K +H+ KL Q + EK++ K + L Q+ +QD V + +
Sbjct: 385 KVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLT 444
Query: 804 XXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK 863
+ L +E+ E + + ++ + A SA ++ + + A++++ K
Sbjct: 445 NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE-KL 503
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
+ ++++++Q+ + ++ K + L KK + E+ ++ + L + L +K
Sbjct: 504 TDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQK 563
Query: 924 AQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ I +++ +LN EK+ + L E+E ++Q ++ + K E L+ +
Sbjct: 564 VEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKW 623
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM 1036
K N+LE ++ K+ L + +++E + ++ EKM
Sbjct: 624 KEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKM 678
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 53.2 bits (122), Expect = 5e-06
Identities = 113/562 (20%), Positives = 243/562 (43%), Gaps = 54/562 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 552 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 611
Query: 656 TQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
++K L E + +EI L + ++ + A Q D + ++ T+TK +++Q
Sbjct: 612 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLTKAKVKLEQQ 669
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D++ +L+ ++D ++ L +K TQ+ + Q L E+ K EL
Sbjct: 670 VDDLEG--SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN 727
Query: 773 NTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+++D L++ K+LQ+ A +E K + + E+
Sbjct: 728 ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE---KLRSDLSRELEE 784
Query: 829 RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+ L EAG A V++ NK + +AE Q+ ++++ + + L +K +
Sbjct: 785 ISERLEEAGGA--TSVQIEMNKKR--EAEFQK-MRRDLEEATLQHEATAAALRKKHADSV 839
Query: 889 TDRQVLTKKIDTLKDEIAKQE-VYKRDLDD---NL-CLRKAQTDITNW-QKQDDELNEKL 942
+ + +K ++ K++ +K +LDD N+ + KA+ ++ + +D++NE
Sbjct: 840 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR 899
Query: 943 NGINKEE------LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
+ + + +++ L + +L +Q E +S+L + + +LE L + +
Sbjct: 900 SKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE-DLKRQL 958
Query: 997 EKKFREKMYELHVTKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRG 1053
E++ + K H ++ D +RE + E R + N + + WR Y
Sbjct: 959 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR-VLSKANSEVAQ-WRTKY-- 1014
Query: 1054 NDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACL--IIRLAL 1111
+ D I+ +TE +E ++K R+ +++ VE + +CS+ +K L I +
Sbjct: 1015 -ETDAIQ-RTE---ELEEAKKKLAQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLM 1068
Query: 1112 AETFSSRFGILALDEPTTNLDQ 1133
+ S ALD+ N D+
Sbjct: 1069 VDVERSNAAAAALDKKQRNFDK 1090
Score = 52.4 bits (120), Expect = 9e-06
Identities = 160/845 (18%), Positives = 347/845 (41%), Gaps = 83/845 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ + +++K+R D ++ L+ + E A ++E + K+ F K
Sbjct: 755 EELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 812
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K + +V
Sbjct: 813 MRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 871
Query: 288 TNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXX 346
+N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 872 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLD 931
Query: 347 XXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA 406
+T Q +A+N L Q ++ +
Sbjct: 932 EKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARHDCDLL 982
Query: 407 VEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E L K K L E
Sbjct: 983 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAE 1040
Query: 464 GNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V + + + K + ++NE+ L+ ++++ + L E + +
Sbjct: 1041 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 1100
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPL 580
+++ ++ + Q +LS T + KL+ N + S+ + +K + K+ L
Sbjct: 1101 ESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQEEISDL 1151
Query: 581 CNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLN 633
+ G ++ E M + LE+ L+ K + E +K+
Sbjct: 1152 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1211
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD+ ++
Sbjct: 1212 ERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGDLNEME 1265
Query: 694 RYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + + + D+++ LD A D K+ I+ + R Q +L
Sbjct: 1266 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1325
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
++ + A++EL+ T ++VQ + +L KK++ +D
Sbjct: 1326 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ-------- 1377
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP 867
T +E A++E A+ + + D +A +A+ K + A +++ KKN+
Sbjct: 1378 --TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-MKKNME 1426
Query: 868 REMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
+ ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +RK++
Sbjct: 1427 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGMRKSER 1484
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
I Q +E ++ N + ++L +K L +K K ++AE A + L K K ++
Sbjct: 1485 RIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFRK-VQH 1540
Query: 987 ELEKS 991
EL+++
Sbjct: 1541 ELDEA 1545
>BX537759-1|CAD97828.1| 1763|Homo sapiens hypothetical protein
protein.
Length = 1763
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + ++++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFQERFQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D K+E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQKRERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 37.1 bits (82), Expect = 0.38
Identities = 68/324 (20%), Positives = 129/324 (39%), Gaps = 25/324 (7%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKV-----EV 846
A P E +E A+ E + E A + E+
Sbjct: 248 ACPDENVSSGELRGLCA-APREEKERETEAAQMEHQKERNSFQERFQALEEDLREKEREI 306
Query: 847 AFNKVKSL--DAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDE 904
A K SL D IQ +E +K++E N ++ + R+ L K E
Sbjct: 307 ATEKKNSLKRDKAIQGLTMALKSKE-KKVEELNSEIEKLSAAFAKAREALQK---AQTQE 362
Query: 905 IAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKESLI---I 958
E Y+ L L A ++ ++ L + I +E +L +K + +
Sbjct: 363 FQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQKRERLEKDL 422
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
++ + K +CT + +L+ ++ RN E EK++ + E +LH + + K
Sbjct: 423 EEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHNQEQVIK 480
Query: 1016 DIREYAVALDKCLMEFHREKMENI 1039
+ E D L +F+ + +E I
Sbjct: 481 HLTESTNQKDVLLQKFNEKDLEVI 504
Score = 32.7 bits (71), Expect = 8.2
Identities = 44/212 (20%), Positives = 91/212 (42%), Gaps = 8/212 (3%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E+ +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFQERFQALEEDLRE 301
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 52.8 bits (121), Expect = 7e-06
Identities = 113/562 (20%), Positives = 243/562 (43%), Gaps = 54/562 (9%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 157 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 216
Query: 656 TQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
++K L E + +EI L + ++ + A Q D + ++ T+TK +++Q
Sbjct: 217 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLTKAKVKLEQQ 274
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D++ +L+ ++D ++ L +K TQ+ + Q L E+ K EL
Sbjct: 275 VDDLEG--SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN 332
Query: 773 NTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+++D L++ K+LQ+ A +E K + + E+
Sbjct: 333 ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVE---KLRSDLSRELEE 389
Query: 829 RNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIM 888
+ L EAG A V++ NK + +AE Q+ ++++ + + L +K +
Sbjct: 390 ISERLEEAGGA--TSVQIEMNKKR--EAEFQK-MRRDLEEATLQHEATAAALRKKHADSV 444
Query: 889 TDRQVLTKKIDTLKDEIAKQE-VYKRDLDD---NL-CLRKAQTDITNW-QKQDDELNEKL 942
+ + +K ++ K++ +K +LDD N+ + KA+ ++ + +D++NE
Sbjct: 445 AELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHR 504
Query: 943 NGINKEE------LNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDI 996
+ + + +++ L + +L +Q E +S+L + + +LE L + +
Sbjct: 505 SKAEETQRSVNDLTSQQAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE-DLKRQL 563
Query: 997 EKKFREKMYELHVTKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRG 1053
E++ + K H ++ D +RE + E R + N + + WR Y
Sbjct: 564 EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR-VLSKANSEVAQ-WRTKY-- 619
Query: 1054 NDIDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACL--IIRLAL 1111
+ D I+ +TE +E ++K R+ +++ VE + +CS+ +K L I +
Sbjct: 620 -ETDAIQ-RTE---ELEEAKKKLAQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLM 673
Query: 1112 AETFSSRFGILALDEPTTNLDQ 1133
+ S ALD+ N D+
Sbjct: 674 VDVERSNAAAAALDKKQRNFDK 695
Score = 52.4 bits (120), Expect = 9e-06
Identities = 160/845 (18%), Positives = 347/845 (41%), Gaps = 83/845 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ + +++K+R D ++ L+ + E A ++E + K+ F K
Sbjct: 360 EELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQK 417
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K + +V
Sbjct: 418 MRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 476
Query: 288 TNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXX 346
+N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 477 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQQAKLQTENGELSRQLD 536
Query: 347 XXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA 406
+T Q +A+N L Q ++ +
Sbjct: 537 EKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARHDCDLL 587
Query: 407 VEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E L K K L E
Sbjct: 588 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAE 645
Query: 464 GNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V + + + K + ++NE+ L+ ++++ + L E + +
Sbjct: 646 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 705
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPL 580
+++ ++ + Q +LS T + KL+ N + S+ + +K + K+ L
Sbjct: 706 ESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQEEISDL 756
Query: 581 CNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLN 633
+ G ++ E M + LE+ L+ K + E +K+
Sbjct: 757 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 816
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD+ ++
Sbjct: 817 ERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGDLNEME 870
Query: 694 RYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + + + D+++ LD A D K+ I+ + R Q +L
Sbjct: 871 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 930
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
++ + A++EL+ T ++VQ + +L KK++ +D
Sbjct: 931 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ-------- 982
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP 867
T +E A++E A+ + + D +A +A+ K + A +++ KKN+
Sbjct: 983 --TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-MKKNME 1031
Query: 868 REMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
+ ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +RK++
Sbjct: 1032 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGMRKSER 1089
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
I Q +E ++ N + ++L +K L +K K ++AE A + L K K ++
Sbjct: 1090 RIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFRK-VQH 1145
Query: 987 ELEKS 991
EL+++
Sbjct: 1146 ELDEA 1150
>AL590642-2|CAH70770.1| 862|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 862
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>AL590642-1|CAH70769.1| 1893|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1893
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>AL391870-2|CAI40925.1| 1893|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1893
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>AL391870-1|CAI40926.1| 862|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 862
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>AL353736-2|CAI40654.1| 862|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 862
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>AL353736-1|CAI40653.1| 1893|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1893
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>AL138836-2|CAI16963.1| 1893|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 1893
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>AL138836-1|CAI16964.1| 862|Homo sapiens CDK5 regulatory subunit
associated protein 2 protein.
Length = 862
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 52.8 bits (121), Expect = 7e-06
Identities = 109/560 (19%), Positives = 233/560 (41%), Gaps = 50/560 (8%)
Query: 603 MNVPGKLEKVTEDLQRASAKKDEILSMK-SLNEKITTLK----DTEIP--QLEKRIVDVD 655
+ + K++++ E L+ E+ + K L ++ + LK D E+ ++EK +
Sbjct: 913 IQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATE 972
Query: 656 TQIKTLNETV---EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
++K L E + +EI L + ++ + A Q D + ++ T+TK +++Q
Sbjct: 973 NKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE--DKVNTLTKAKVKLEQQ 1030
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
D++ +L+ ++D ++ L +K TQ+ + Q L E+ K EL
Sbjct: 1031 VDDLEG--SLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQQLDERLKKKDFELN 1088
Query: 773 NTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVR 828
+++D L++ K+LQ+ A +E + E+
Sbjct: 1089 ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISE 1148
Query: 829 RNRDLIEAGSAYI---AKVEVAFNKV-KSLDAEIQQHK------KKNVPREMEKIQEAND 878
R + A S I K E F K+ + L+ QH+ +K + ++ E D
Sbjct: 1149 RLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQID 1208
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL 938
L ++++ ++ ++D + + + K +L + +C R + + + + +E
Sbjct: 1209 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANL-EKMC-RTLEDQMNEHRSKAEET 1266
Query: 939 NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+N + +++ L + +L +Q E +S+L + + +LE L + +E+
Sbjct: 1267 QRSVNDLT----SQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLE-DLKRQLEE 1321
Query: 999 KFREKMYELHVTKAIDKD---IREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGND 1055
+ + K H ++ D +RE + E R + N + + WR Y +
Sbjct: 1322 EVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQR-VLSKANSEVAQ-WRTKY---E 1376
Query: 1056 IDYIEIKTEGNLTVESERRKYDYRVVQSKNGVEIDMRGRCSAGQKVLACL--IIRLALAE 1113
D I+ +TE +E ++K R+ +++ VE + +CS+ +K L I + +
Sbjct: 1377 TDAIQ-RTE---ELEEAKKKLAQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLMVD 1431
Query: 1114 TFSSRFGILALDEPTTNLDQ 1133
S ALD+ N D+
Sbjct: 1432 VERSNAAAAALDKKQRNFDK 1451
Score = 52.0 bits (119), Expect = 1e-05
Identities = 160/845 (18%), Positives = 347/845 (41%), Gaps = 83/845 (9%)
Query: 176 ERFDEIFDADKYSDCLDRLKKIRKDYAQNLK-LLENYATTVKAKQKELEDSYKKNTSFNK 234
E +E +A++ + +++K+R D ++ L+ + E A ++E + K+ F K
Sbjct: 1116 EELEEELEAERTARA--KVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQK 1173
Query: 235 -----EEEKIANEKSSNEIEYNKFILLESQNQEKID--KRNEQIVETAKIAEIENITEVQ 287
EE + +E ++ + K ++ E+ID +R +Q +E K + +V
Sbjct: 1174 MRRDLEEATLQHEATAAALR-KKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVT 1232
Query: 288 TNEEAENATKTILEKV-ESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXX 346
+N E K LEK+ +L+ +S+A+E ++ + T+
Sbjct: 1233 SNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLD 1292
Query: 347 XXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIEECQQEINEDEKA 406
+T Q +A+N L Q ++ +
Sbjct: 1293 EKEALISQLTRGKLTYTQQ--------LEDLKRQLEEEVKAKNAL-AHALQSARHDCDLL 1343
Query: 407 VEQYEQEMD---ELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELL 463
EQYE+E + EL + ++K + A+ + K + +T+E L K K L E
Sbjct: 1344 REQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEE--LEEAKKKLAQRLQEAE 1401
Query: 464 GNVPEKDFAVT-INKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRSELT 522
V + + + K + ++NE+ L+ ++++ + L E + +
Sbjct: 1402 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYE 1461
Query: 523 KAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKD--NSCCPL 580
+++ ++ + Q +LS T + KL+ N + S+ + +K + K+ L
Sbjct: 1462 ESQSELESS---QKEARSLS---TELFKLK---NAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 581 CNR-GFENES--EXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK----KDEILSMKSLN 633
+ G ++ E M + LE+ L+ K + E +K+
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
Query: 634 EKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLD 693
E+ KD E+ Q ++ + V + +L +++ T S E + K++ GD+ ++
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRV---VDSLQTSLDAETRSRNEA---LRVKKKMEGDLNEME 1626
Query: 694 RYIQEIKTVTKKFEAVKEQCGDV--DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ + + + + + D+++ LD A D K+ I+ + R Q +L
Sbjct: 1627 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1686
Query: 752 AHNKKLQTLYEKKTKAKEELLNTQKKVQDI----VNLEESKKQLQSDCXXXXXXXXXXXX 807
++ + A++EL+ T ++VQ + +L KK++ +D
Sbjct: 1687 ELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ-------- 1738
Query: 808 AITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVP 867
T +E A++E A+ + + D +A +A+ K + A +++ KKN+
Sbjct: 1739 --TEVEEAVQECRNAEEKAKKAITD-----AAMMAE---ELKKEQDTSAHLER-MKKNME 1787
Query: 868 REMEKIQEANDKLME-KQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQT 926
+ ++ +Q D+ + K Q L ++ L++E+ ++ KR+ + +RK++
Sbjct: 1788 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQ--KRNAESVKGMRKSER 1845
Query: 927 DITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRN 986
I Q +E ++ N + ++L +K L +K K ++AE A + L K K ++
Sbjct: 1846 RIKELTYQTEE--DRKNLLRLQDLVDKLQLKVKAYKRQAEEAE-EQANTNLSKFRK-VQH 1901
Query: 987 ELEKS 991
EL+++
Sbjct: 1902 ELDEA 1906
>AF448860-1|AAP41926.1| 1893|Homo sapiens hypothetical protein
protein.
Length = 1893
Score = 52.8 bits (121), Expect = 7e-06
Identities = 92/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + +E++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFEERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFEERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/213 (21%), Positives = 94/213 (44%), Gaps = 10/213 (4%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSL-SKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E + +E + +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFEERI-QALEEDLRE 301
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 52.4 bits (120), Expect = 9e-06
Identities = 143/829 (17%), Positives = 313/829 (37%), Gaps = 55/829 (6%)
Query: 264 IDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKK 323
I ++++++ + A+ + QT ++ E A++ + +VE L S K ++ Q E +K
Sbjct: 514 IQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEK 573
Query: 324 AQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXX 383
+ R H Q + + +
Sbjct: 574 QEA----TRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANE 629
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
+ + + ++ + Q+E E + VE+ + ++ Q+ + Q Q A+L E ++ E K
Sbjct: 630 ARDSA-QTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL-ELQLRSEQQKA 687
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
EK+ + + K L E L + E VT E E R L
Sbjct: 688 TEKERVA---QEKDQLQEQLQALKE-SLKVTKGSLEEEKRR----AADALEEQQRCISEL 739
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSK-YTTTVEKLQDEQNVLQSSM 562
+AE + + E R EL E++ G + L + + E L+ E ++
Sbjct: 740 KAETRSLVEQHKRERKEL---EEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQ 796
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
QL R +++ E M + + EK ++LQ A
Sbjct: 797 HTAESECEQLV-KEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEA--- 852
Query: 623 KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM-TT 681
K+++ ++S +E + + E+ +L + Q++ +++ L ++KM T
Sbjct: 853 KEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAAT 912
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRN 741
+K++ ++ + ++ +T +++ + GD E L+ +Q F + L+
Sbjct: 913 SKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEW-LEEQQGRQ--FCSTQAALQA 969
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXX 801
+ ++ N + L E + + +EE ++ +++ L + + + Q+D
Sbjct: 970 MEREAEQMGNELERLRAALMESQGQQQEE---RGQQEREVARLTQERGRAQAD------- 1019
Query: 802 XXXXXXAITPLEVALKEKI-EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ 860
A LE+ L+ + E + E L A + K + K++ L+A
Sbjct: 1020 LALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGK-DQELAKLRGLEAA--- 1075
Query: 861 HKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC 920
+ K + + +++ ++L +K+K+ + ++ + K E + ++
Sbjct: 1076 -QIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVS---- 1130
Query: 921 LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG----ALSE 976
K + Q+Q D L L +L Q +L ++KA+ G AL+
Sbjct: 1131 --KLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQL-EEKAQELGHSQSALAS 1187
Query: 977 LKKSLKGFRNELEKSLSKDIEKKFR--EKMYELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
++ L FR +++ + E K + E ++ + E L++ ++E E
Sbjct: 1188 AQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGE 1247
Query: 1035 KMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQS 1083
E +++ E + + ++ +T N +ER VQS
Sbjct: 1248 SKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQS 1296
Score = 46.4 bits (105), Expect = 6e-04
Identities = 50/227 (22%), Positives = 94/227 (41%), Gaps = 7/227 (3%)
Query: 693 DRYIQEIKTVTKKFEA--VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
++Y+QE+ V E + Q + L+V TAK K K+ R R + ++KL
Sbjct: 1474 EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKL 1533
Query: 751 NAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESK-KQLQSDCXXXXXXXXXXXXAI 809
A ++L+ ++TK EEL +++ K K +Q+ +
Sbjct: 1534 TAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQL 1593
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSL-DAEIQQHKKKNVPR 868
L+ L +K +A + +A + Y AK + + L E Q + K +
Sbjct: 1594 NELQAQLSQKEQAAEHY---KLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRA 1650
Query: 869 EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
E E++ + K K+ + LT ++ +L+ ++A + RDL
Sbjct: 1651 EAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1697
Score = 44.4 bits (100), Expect = 0.002
Identities = 70/369 (18%), Positives = 151/369 (40%), Gaps = 33/369 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI--QEIKTVT 703
QLEK + K L E E + L + E+ ++ Q+ + P + ++ T
Sbjct: 361 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLS---QLQDNPPQEKGEVLGDVLQLET 417
Query: 704 KKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK 763
K EA + + +++ ++ + K+ R + +++L++ LQ+
Sbjct: 418 LKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISN 477
Query: 764 KTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAK 823
++AKEEL Q L L S+ + L+ KEK
Sbjct: 478 LSQAKEEL--EQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQL 535
Query: 824 TEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEK 883
+ +++ +A +VE + +K + ++++ +K + Q+ E+
Sbjct: 536 AQTLQQQE---QASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEER 592
Query: 884 QKQIMTDRQVLTKKIDTL-KDEIAKQEVYKRDLD-DNLCLRKAQTDITNWQKQDDELNEK 941
+ + +R K+++ L K++ AK E+ ++ L N AQT +T Q++ EL+ K
Sbjct: 593 EASLR-ERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRK 651
Query: 942 LNGIN------KEELNEKESLIIK--------------QTKLFQQKAECTGALSELKKSL 981
+ + ++E +E ++ + + + ++ Q+K + L LK+SL
Sbjct: 652 VEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESL 711
Query: 982 KGFRNELEK 990
K + LE+
Sbjct: 712 KVTKGSLEE 720
Score = 42.3 bits (95), Expect = 0.010
Identities = 86/519 (16%), Positives = 209/519 (40%), Gaps = 36/519 (6%)
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
A+ N +E + E+ E+ K + + + ++ + Q+I +L A L EK+ + K
Sbjct: 224 ADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL----ALLNEKQAASP---LEPK 276
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAE 506
+L L++K+++ M L + + + + ++ ++ +
Sbjct: 277 ELEELRDKNESLTMRLHETLKQ---CQDLKTEKSQMDRKINQLSEENGDLSFKLREFASH 333
Query: 507 RKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIIN 566
+ ++++LNE E +KA + + + LS + L+++ +LQ + +
Sbjct: 334 LQQLQDALNELTEEHSKATQEWLEK--QAQLEKELSAALQDKKCLEEKNEILQGKLSQLE 391
Query: 567 KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPG-KLEKVTEDLQRASAKKDE 625
++ QL+DN P +G + +L+ E L+ +++
Sbjct: 392 EHLSQLQDN---PPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEA 448
Query: 626 ILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT-AKQ 684
K L E+ + E QL I D+ + I L++ EE+ + ++T
Sbjct: 449 ----KLLAERGHF--EEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVAS 502
Query: 685 IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD--FKQKISTLRNR 742
+ ++ L+ IQ+ ++ +K+Q + +++ + +Q + ++ L +
Sbjct: 503 LTSELTTLNATIQQ---QDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSS 559
Query: 743 VKTTQKKLNAHNKKLQTLYEKK-----TKAKEELLNTQKKVQDIVNLEESKKQLQSDCXX 797
+K +++L +K + + T A+E + +++ + LE +K+ +
Sbjct: 560 LKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEI 619
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
A + ++ + K E+ R+ +L A+ E + + + E
Sbjct: 620 LQQQLQVANEARDSAQTSVTQAQREKAELSRKVEEL--QACVETARQEQHEAQAQVAELE 677
Query: 858 IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+Q ++ E E++ + D+L E Q Q + + +TK
Sbjct: 678 LQLRSEQQKATEKERVAQEKDQLQE-QLQALKESLKVTK 715
Score = 40.7 bits (91), Expect = 0.031
Identities = 82/444 (18%), Positives = 187/444 (42%), Gaps = 39/444 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++ ++ + L + +DE+ + N K+ T KD +I +++RI ++ LNE
Sbjct: 215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRI----DRLALLNEKQAA 270
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ E E+ + + + + Q++KT + + Q + + +++
Sbjct: 271 SPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSF----- 325
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
K +F + L++ + ++ H+K Q EK+ + ++EL +QD LEE
Sbjct: 326 KLREFASHLQQLQDALNELTEE---HSKATQEWLEKQAQLEKEL---SAALQDKKCLEEK 379
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+ LQ L + K EV+ D+++ + +A
Sbjct: 380 NEILQGKLSQLEEH----------LSQLQDNPPQEKGEVL---GDVLQLETLKQEAATLA 426
Query: 848 FNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQK--QIMTDRQVLTKKIDTLKDEI 905
N + L A ++ + + +E + + E EKQ+ ++TD Q + K+E+
Sbjct: 427 ANNTQ-LQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEEL 485
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ 965
+Q + +++T + +++L G+ K++ EK++ + + + +
Sbjct: 486 -EQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL-KQQAKEKQAQLAQTLQQQE 543
Query: 966 QKAE-CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD--IREYAV 1022
Q ++ + +L SLK +L++ K ++ R+ + T A +++ +RE
Sbjct: 544 QASQGLRHQVEQLSSSLKQKEQQLKEVAEK--QEATRQDHAQQLATAAEEREASLRERDA 601
Query: 1023 ALDKCLMEFHREKMENINMIIREL 1046
AL K L +EK + ++ ++L
Sbjct: 602 AL-KQLEALEKEKAAKLEILQQQL 624
Score = 33.1 bits (72), Expect = 6.2
Identities = 35/217 (16%), Positives = 84/217 (38%), Gaps = 7/217 (3%)
Query: 242 EKSSNEIEYNKFILLESQNQEKIDKRNE---QIVETAKIAEIENITEVQTNEEAENATKT 298
EK + E K LE+ +++++ + Q+ E E E+ + EA T+
Sbjct: 1058 EKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEP 1117
Query: 299 ILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXX 358
K+E+L+++ + Q +++++A ++
Sbjct: 1118 TGPKLEALRAEVSKLEQQCQKQQEQADS-LERSLEAERASRAERDSALETLQGQLEEKAQ 1176
Query: 359 DITSANQSXXXXXXXXXXXXXXXXXHKQAENE--LNIEECQQEINEDEKAVEQYEQEMDE 416
++ + + H +AE+E + +QE + E+E+
Sbjct: 1177 ELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSI 1236
Query: 417 LSQKITKLQKQTAKLKEKEMIEENLKTK-EKQLIVLK 452
L++++ + + ++ +LK M E K E++L +L+
Sbjct: 1237 LNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQ 1273
>AF254756-1|AAK13079.1| 698|Homo sapiens predicted testis protein
protein.
Length = 698
Score = 52.4 bits (120), Expect = 9e-06
Identities = 75/401 (18%), Positives = 172/401 (42%), Gaps = 34/401 (8%)
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDT---EIPQLEKRIVDVDTQIKTLN-ETVEEITM 670
DL+R + ++D SL E++ ++T E LE+RI +++ + L+ E +E+++
Sbjct: 111 DLRRMTTERD------SLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSN 164
Query: 671 SLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
+ E T K+ M L R K + + E +++ + + +
Sbjct: 165 MTLMKETISTVEKE----MKSLAR-----KAMDTESELGRQKAENNSLRLLYENTEKDLS 215
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
D ++ ++ + ++ TQ+K+ ++K+ + +EE+ + D L + K+
Sbjct: 216 DTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLND---LAKEKEC 272
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK 850
LQ+ ++ E + E+ + +R EA V +
Sbjct: 273 LQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRRQ 332
Query: 851 VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
+ + E+ Q + RE + + ND L E+ + + Q L+KK++ +E+ ++
Sbjct: 333 LDETNDELAQ-----IARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNEL--NDI 385
Query: 911 YKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAEC 970
++ D NL + K + + + + ++ ++ E+L N++ N + + K E
Sbjct: 386 KQKVQDTNLEVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLEL 445
Query: 971 TGALSE---LKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
A +E LK+ + E+E+ L + E+ ++ ++ LH
Sbjct: 446 ITAEAEGNRLKEKVDSLNREVEQHL--NAERSYKSQISTLH 484
Score = 40.7 bits (91), Expect = 0.031
Identities = 50/295 (16%), Positives = 124/295 (42%), Gaps = 10/295 (3%)
Query: 608 KLEKVTEDLQRASAKKDEIL-SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+L++ ++L + + ++D + +L E+ K E L K++ D ++ + + V+
Sbjct: 332 QLDETNDELAQIARERDILAHDNDNLQEQFAKAKQ-ENQALSKKLNDTHNELNDIKQKVQ 390
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ + E + K + + +++ + +E Q ++ + L++ T
Sbjct: 391 DTNL---EVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELIT 447
Query: 727 AKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ-KKVQDIVN 783
A+ K+K+ +L V+ ++ ++ TL++ K +EEL Q +KV + +
Sbjct: 448 AEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALAD 507
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV-VRRNRDLIEAGSAYIA 842
L +++ +E+ E A +E+ + R++ E S
Sbjct: 508 LSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNL 567
Query: 843 KVEVAFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+ + N+ K ++I Q K+ + E + A +K+ + + + R V+T+
Sbjct: 568 EALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQ 622
>AC019097-1|AAY14820.1| 698|Homo sapiens unknown protein.
Length = 698
Score = 52.4 bits (120), Expect = 9e-06
Identities = 75/401 (18%), Positives = 172/401 (42%), Gaps = 34/401 (8%)
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDT---EIPQLEKRIVDVDTQIKTLN-ETVEEITM 670
DL+R + ++D SL E++ ++T E LE+RI +++ + L+ E +E+++
Sbjct: 111 DLRRMTTERD------SLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSN 164
Query: 671 SLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
+ E T K+ M L R K + + E +++ + + +
Sbjct: 165 MTLMKETISTVEKE----MKSLAR-----KAMDTESELGRQKAENNSLRLLYENTEKDLS 215
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
D ++ ++ + ++ TQ+K+ ++K+ + +EE+ + D L + K+
Sbjct: 216 DTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLND---LAKEKEC 272
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK 850
LQ+ ++ E + E+ + +R EA V +
Sbjct: 273 LQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRRQ 332
Query: 851 VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
+ + E+ Q + RE + + ND L E+ + + Q L+KK++ +E+ ++
Sbjct: 333 LDETNDELAQ-----IARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNEL--NDI 385
Query: 911 YKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAEC 970
++ D NL + K + + + + ++ ++ E+L N++ N + + K E
Sbjct: 386 KQKVQDTNLEVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLEL 445
Query: 971 TGALSE---LKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
A +E LK+ + E+E+ L + E+ ++ ++ LH
Sbjct: 446 ITAEAEGNRLKEKVDSLNREVEQHL--NAERSYKSQISTLH 484
Score = 40.7 bits (91), Expect = 0.031
Identities = 50/295 (16%), Positives = 124/295 (42%), Gaps = 10/295 (3%)
Query: 608 KLEKVTEDLQRASAKKDEIL-SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+L++ ++L + + ++D + +L E+ K E L K++ D ++ + + V+
Sbjct: 332 QLDETNDELAQIARERDILAHDNDNLQEQFAKAKQ-ENQALSKKLNDTHNELNDIKQKVQ 390
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ + E + K + + +++ + +E Q ++ + L++ T
Sbjct: 391 DTNL---EVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELIT 447
Query: 727 AKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ-KKVQDIVN 783
A+ K+K+ +L V+ ++ ++ TL++ K +EEL Q +KV + +
Sbjct: 448 AEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALAD 507
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV-VRRNRDLIEAGSAYIA 842
L +++ +E+ E A +E+ + R++ E S
Sbjct: 508 LSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNL 567
Query: 843 KVEVAFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+ + N+ K ++I Q K+ + E + A +K+ + + + R V+T+
Sbjct: 568 EALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQ 622
>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
protein.
Length = 2121
Score = 52.4 bits (120), Expect = 9e-06
Identities = 143/829 (17%), Positives = 313/829 (37%), Gaps = 55/829 (6%)
Query: 264 IDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKK 323
I ++++++ + A+ + QT ++ E A++ + +VE L S K ++ Q E +K
Sbjct: 520 IQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEK 579
Query: 324 AQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXX 383
+ R H Q + + +
Sbjct: 580 QEA----TRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANE 635
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKT 443
+ + + ++ + Q+E E + VE+ + ++ Q+ + Q Q A+L E ++ E K
Sbjct: 636 ARDSA-QTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL-ELQLRSEQQKA 693
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXL 503
EK+ + + K L E L + E VT E E R L
Sbjct: 694 TEKERVA---QEKDQLQEQLQALKE-SLKVTKGSLEEEKRR----AADALEEQQRCISEL 745
Query: 504 EAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSK-YTTTVEKLQDEQNVLQSSM 562
+AE + + E R EL E++ G + L + + E L+ E ++
Sbjct: 746 KAETRSLVEQHKRERKEL---EEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQ 802
Query: 563 FIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK 622
QL R +++ E M + + EK ++LQ A
Sbjct: 803 HTAESECEQLV-KEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEA--- 858
Query: 623 KDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM-TT 681
K+++ ++S +E + + E+ +L + Q++ +++ L ++KM T
Sbjct: 859 KEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAAT 918
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRN 741
+K++ ++ + ++ +T +++ + GD E L+ +Q F + L+
Sbjct: 919 SKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEW-LEEQQGRQ--FCSTQAALQA 975
Query: 742 RVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXX 801
+ ++ N + L E + + +EE ++ +++ L + + + Q+D
Sbjct: 976 MEREAEQMGNELERLRAALMESQGQQQEE---RGQQEREVARLTQERGRAQAD------- 1025
Query: 802 XXXXXXAITPLEVALKEKI-EAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ 860
A LE+ L+ + E + E L A + K + K++ L+A
Sbjct: 1026 LALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGK-DQELAKLRGLEAA--- 1081
Query: 861 HKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLC 920
+ K + + +++ ++L +K+K+ + ++ + K E + ++
Sbjct: 1082 -QIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVS---- 1136
Query: 921 LRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG----ALSE 976
K + Q+Q D L L +L Q +L ++KA+ G AL+
Sbjct: 1137 --KLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQL-EEKAQELGHSQSALAS 1193
Query: 977 LKKSLKGFRNELEKSLSKDIEKKFR--EKMYELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
++ L FR +++ + E K + E ++ + E L++ ++E E
Sbjct: 1194 AQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGE 1253
Query: 1035 KMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERRKYDYRVVQS 1083
E +++ E + + ++ +T N +ER VQS
Sbjct: 1254 SKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQS 1302
Score = 46.4 bits (105), Expect = 6e-04
Identities = 50/227 (22%), Positives = 94/227 (41%), Gaps = 7/227 (3%)
Query: 693 DRYIQEIKTVTKKFEA--VKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKL 750
++Y+QE+ V E + Q + L+V TAK K K+ R R + ++KL
Sbjct: 1480 EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKL 1539
Query: 751 NAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESK-KQLQSDCXXXXXXXXXXXXAI 809
A ++L+ ++TK EEL +++ K K +Q+ +
Sbjct: 1540 TAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQL 1599
Query: 810 TPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSL-DAEIQQHKKKNVPR 868
L+ L +K +A + +A + Y AK + + L E Q + K +
Sbjct: 1600 NELQAQLSQKEQAAEHY---KLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRA 1656
Query: 869 EMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
E E++ + K K+ + LT ++ +L+ ++A + RDL
Sbjct: 1657 EAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1703
Score = 44.4 bits (100), Expect = 0.002
Identities = 70/369 (18%), Positives = 151/369 (40%), Gaps = 33/369 (8%)
Query: 646 QLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYI--QEIKTVT 703
QLEK + K L E E + L + E+ ++ Q+ + P + ++ T
Sbjct: 367 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLS---QLQDNPPQEKGEVLGDVLQLET 423
Query: 704 KKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEK 763
K EA + + +++ ++ + K+ R + +++L++ LQ+
Sbjct: 424 LKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISN 483
Query: 764 KTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAK 823
++AKEEL Q L L S+ + L+ KEK
Sbjct: 484 LSQAKEEL--EQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQL 541
Query: 824 TEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEK 883
+ +++ +A +VE + +K + ++++ +K + Q+ E+
Sbjct: 542 AQTLQQQE---QASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEER 598
Query: 884 QKQIMTDRQVLTKKIDTL-KDEIAKQEVYKRDLD-DNLCLRKAQTDITNWQKQDDELNEK 941
+ + +R K+++ L K++ AK E+ ++ L N AQT +T Q++ EL+ K
Sbjct: 599 EASLR-ERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRK 657
Query: 942 LNGIN------KEELNEKESLIIK--------------QTKLFQQKAECTGALSELKKSL 981
+ + ++E +E ++ + + + ++ Q+K + L LK+SL
Sbjct: 658 VEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESL 717
Query: 982 KGFRNELEK 990
K + LE+
Sbjct: 718 KVTKGSLEE 726
Score = 42.3 bits (95), Expect = 0.010
Identities = 86/519 (16%), Positives = 209/519 (40%), Gaps = 36/519 (6%)
Query: 387 AENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEK 446
A+ N +E + E+ E+ K + + + ++ + Q+I +L A L EK+ + K
Sbjct: 230 ADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL----ALLNEKQAASP---LEPK 282
Query: 447 QLIVLKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAE 506
+L L++K+++ M L + + + + ++ ++ +
Sbjct: 283 ELEELRDKNESLTMRLHETLKQ---CQDLKTEKSQMDRKINQLSEENGDLSFKLREFASH 339
Query: 507 RKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIIN 566
+ ++++LNE E +KA + + + LS + L+++ +LQ + +
Sbjct: 340 LQQLQDALNELTEEHSKATQEWLEK--QAQLEKELSAALQDKKCLEEKNEILQGKLSQLE 397
Query: 567 KYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPG-KLEKVTEDLQRASAKKDE 625
++ QL+DN P +G + +L+ E L+ +++
Sbjct: 398 EHLSQLQDN---PPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEA 454
Query: 626 ILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTT-AKQ 684
K L E+ + E QL I D+ + I L++ EE+ + ++T
Sbjct: 455 ----KLLAERGHF--EEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVAS 508
Query: 685 IHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVD--FKQKISTLRNR 742
+ ++ L+ IQ+ ++ +K+Q + +++ + +Q + ++ L +
Sbjct: 509 LTSELTTLNATIQQ---QDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSS 565
Query: 743 VKTTQKKLNAHNKKLQTLYEKK-----TKAKEELLNTQKKVQDIVNLEESKKQLQSDCXX 797
+K +++L +K + + T A+E + +++ + LE +K+ +
Sbjct: 566 LKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEI 625
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
A + ++ + K E+ R+ +L A+ E + + + E
Sbjct: 626 LQQQLQVANEARDSAQTSVTQAQREKAELSRKVEEL--QACVETARQEQHEAQAQVAELE 683
Query: 858 IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+Q ++ E E++ + D+L E Q Q + + +TK
Sbjct: 684 LQLRSEQQKATEKERVAQEKDQLQE-QLQALKESLKVTK 721
Score = 40.7 bits (91), Expect = 0.031
Identities = 82/444 (18%), Positives = 187/444 (42%), Gaps = 39/444 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++ ++ + L + +DE+ + N K+ T KD +I +++RI ++ LNE
Sbjct: 221 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRI----DRLALLNEKQAA 276
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ E E+ + + + + Q++KT + + Q + + +++
Sbjct: 277 SPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSF----- 331
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
K +F + L++ + ++ H+K Q EK+ + ++EL +QD LEE
Sbjct: 332 KLREFASHLQQLQDALNELTEE---HSKATQEWLEKQAQLEKEL---SAALQDKKCLEEK 385
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+ LQ L + K EV+ D+++ + +A
Sbjct: 386 NEILQGKLSQLEEH----------LSQLQDNPPQEKGEVL---GDVLQLETLKQEAATLA 432
Query: 848 FNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQK--QIMTDRQVLTKKIDTLKDEI 905
N + L A ++ + + +E + + E EKQ+ ++TD Q + K+E+
Sbjct: 433 ANNTQ-LQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEEL 491
Query: 906 AKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQ 965
+Q + +++T + +++L G+ K++ EK++ + + + +
Sbjct: 492 -EQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL-KQQAKEKQAQLAQTLQQQE 549
Query: 966 QKAE-CTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD--IREYAV 1022
Q ++ + +L SLK +L++ K ++ R+ + T A +++ +RE
Sbjct: 550 QASQGLRHQVEQLSSSLKQKEQQLKEVAEK--QEATRQDHAQQLATAAEEREASLRERDA 607
Query: 1023 ALDKCLMEFHREKMENINMIIREL 1046
AL K L +EK + ++ ++L
Sbjct: 608 AL-KQLEALEKEKAAKLEILQQQL 630
Score = 33.1 bits (72), Expect = 6.2
Identities = 35/217 (16%), Positives = 84/217 (38%), Gaps = 7/217 (3%)
Query: 242 EKSSNEIEYNKFILLESQNQEKIDKRNE---QIVETAKIAEIENITEVQTNEEAENATKT 298
EK + E K LE+ +++++ + Q+ E E E+ + EA T+
Sbjct: 1064 EKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEP 1123
Query: 299 ILEKVESLKSDHKVQKSQADEEEKKAQGFVDECRSGHTQXXXXXXXXXXXXXXXXXXXXX 358
K+E+L+++ + Q +++++A ++
Sbjct: 1124 TGPKLEALRAEVSKLEQQCQKQQEQADS-LERSLEAERASRAERDSALETLQGQLEEKAQ 1182
Query: 359 DITSANQSXXXXXXXXXXXXXXXXXHKQAENE--LNIEECQQEINEDEKAVEQYEQEMDE 416
++ + + H +AE+E + +QE + E+E+
Sbjct: 1183 ELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSI 1242
Query: 417 LSQKITKLQKQTAKLKEKEMIEENLKTK-EKQLIVLK 452
L++++ + + ++ +LK M E K E++L +L+
Sbjct: 1243 LNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQ 1279
>BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein.
Length = 1022
Score = 52.0 bits (119), Expect = 1e-05
Identities = 86/437 (19%), Positives = 179/437 (40%), Gaps = 22/437 (5%)
Query: 616 LQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEP 675
LQ + E + +K KD + +LEK++ V + + +E+ E
Sbjct: 382 LQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATEL 441
Query: 676 EQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ-VDFKQ 734
E + AKQ E++ + E K+Q + + A+Q K+
Sbjct: 442 EMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQ-----ERLAGEAPAAQQAAQCKE 496
Query: 735 KISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSD 794
+ + ++ TQ+KL +K L ++K +EL + +Q ++ E K+ S+
Sbjct: 497 EAALAGCHLEDTQRKL----QKGLLLDKQKADTIQELQRELQMLQKESSMAE--KEQTSN 550
Query: 795 CXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSL 854
A+ LE + KEK + + V ++ + + + + L
Sbjct: 551 RKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKL 610
Query: 855 DAEIQQHKK-KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKR 913
+ ++Q+ K RE K + ++KLME + + + RQ KK TLK+ K E
Sbjct: 611 EEDLQEATKLLEDKREQLKKSKEHEKLMEGELEAL--RQEFKKKDKTLKENSRKLEEENE 668
Query: 914 DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ-KAECTG 972
+L L+ T + + + + + + +NKE +KESL+ Q +L + + E
Sbjct: 669 NLRAE--LQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHY 726
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDI---REYAVALDKCLM 1029
+ + K + + D+ + + + TK++ + + +E L++ ++
Sbjct: 727 LQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEII 786
Query: 1030 EFHREKMENINMIIREL 1046
+ E+M+ +N +R+L
Sbjct: 787 AY-EERMKKLNTELRKL 802
Score = 49.2 bits (112), Expect = 9e-05
Identities = 79/425 (18%), Positives = 181/425 (42%), Gaps = 46/425 (10%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLK--DTEIPQLEKRIVDVDTQIKTLNETV 665
K + E Q ++ K+ E LS++ L+E + L+ D E QL+K + + D ++ + + +
Sbjct: 538 KESSMAEKEQTSNRKRVEELSLE-LSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRI 596
Query: 666 -----EEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEM 720
E+ ++ E K + L + + K + + EA++++ D +
Sbjct: 597 KHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTL 656
Query: 721 TLDVATAKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKV 778
+ ++ + + ++ +++++ K N + +Q L ++ KE L++ Q ++
Sbjct: 657 KENSRKLEEENENLRAELQCCSTQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQL 716
Query: 779 QDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE--KIEAKTEVVRRNRDLIEA 836
+ E+ Q L AL++ + ++T+ ++++ +
Sbjct: 717 DKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQE 776
Query: 837 GSAYIAKVEVAFN-KVKSLDAEIQQHKKKNVPREME------KIQEANDKLMEKQKQIMT 889
A + + +A+ ++K L+ E+++ + + E+E K++E + ++++ QKQ
Sbjct: 777 KKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQN 836
Query: 890 DRQVLTKKIDTLKDEIAKQEVYKRDL--DDN--LCLRK----------------AQTDIT 929
D ++L K + L++ + K +L DD CL + T++
Sbjct: 837 DLKMLAAKEEQLREFQEEMAALKENLLEDDKEPCCLPQWSVPKDTCRLYRGNDQIMTNLE 896
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELE 989
W KQ NEKL +L E+ I KL +K + L++ K + E+E
Sbjct: 897 QWAKQQKVANEKLG----NQLREQVKYI---AKLSGEKDHLHSVMVHLQQENKKLKKEIE 949
Query: 990 KSLSK 994
+ K
Sbjct: 950 EKKMK 954
Score = 43.2 bits (97), Expect = 0.006
Identities = 81/407 (19%), Positives = 164/407 (40%), Gaps = 28/407 (6%)
Query: 397 QQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHK 456
++E + K VE+ E+ E +K+ K+ +L +K + E+++K + L +K++H+
Sbjct: 544 EKEQTSNRKRVEELSLELSEALRKLENSDKEKRQL-QKTVAEQDMKMND-MLDRIKHQHR 601
Query: 457 TALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNE 516
+ E+D E + R ++ L E K ++L E
Sbjct: 602 E--QGSIKCKLEEDLQEATKLLE-DKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKE 658
Query: 517 RRSELTKAEDKI---YKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLK 573
+L + + + + C TQ + +L+KY T+ + +QD + + + QL
Sbjct: 659 NSRKLEEENENLRAELQCCSTQ-LESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQL- 716
Query: 574 DNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILS-MKSL 632
++ + E + K +DL +A K + + S KSL
Sbjct: 717 --------DKALQKEKHYLQTTITKEAYDA-LSRKSAACQDDLTQALEKLNHVTSETKSL 767
Query: 633 NEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKM-TTAKQIHGDMPM 691
+ +T ++ + QLE+ I+ + ++K LN + ++ E E ++ K++
Sbjct: 768 QQSLTQTQEKK-AQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQ 826
Query: 692 LDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN 751
+ ++ ++ + K A +EQ + EM + D K+ + V +L
Sbjct: 827 VLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLE-DDKEPCCLPQWSVPKDTCRLY 885
Query: 752 AHNKKLQTLYE---KKTKAKEELLNTQ--KKVQDIVNLEESKKQLQS 793
N ++ T E K+ K E L Q ++V+ I L K L S
Sbjct: 886 RGNDQIMTNLEQWAKQQKVANEKLGNQLREQVKYIAKLSGEKDHLHS 932
Score = 41.5 bits (93), Expect = 0.018
Identities = 55/295 (18%), Positives = 117/295 (39%), Gaps = 13/295 (4%)
Query: 168 LDEGKKVKERFDE-IFDAD-KYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDS 225
L+ K K + + + + D K +D LDR+K ++ LE ++ K LED
Sbjct: 568 LENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEE---DLQEATKLLEDK 624
Query: 226 YKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAKIAEIE---N 282
++ + E+ + E + E+ K +N K+++ NE + + + +
Sbjct: 625 REQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESS 684
Query: 283 ITEVQTNEEA-ENATKTILEKVESLKS-DHKVQKSQADEEEKKAQGFVDECRSGHTQXXX 340
+ + T+++ ++ K I + ESL S ++ K+ E+ E ++
Sbjct: 685 LNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSA 744
Query: 341 XXXXXXXXXXXXXXXXXXDITSANQSXXXXXXXXXXXXXXXXXHKQAENELNIE--ECQQ 398
+ S QS +++ +LN E + +
Sbjct: 745 ACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRG 804
Query: 399 EINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E E V ++++++E+S ++ + QKQ LK EE L+ ++++ LK
Sbjct: 805 FHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALK 859
Score = 37.1 bits (82), Expect = 0.38
Identities = 61/294 (20%), Positives = 125/294 (42%), Gaps = 27/294 (9%)
Query: 60 GSRNECFVHDAKVNRSTEVLGQVKLKIVNAKDKQLEVTRSMKVTA-----LAKKKTKFQT 114
G R E H + ++ +L Q +L+ + QLE T + K+T L +K Q
Sbjct: 359 GLREETSAHIERKDKDITIL-QCRLQ-----ELQLEFTETQKLTLKKDKFLQEKDEMLQE 412
Query: 115 LDSFLSTVDES--GKTKDVSSR---CADLDILMHE-ELGVSKAILNSVVFCHQEDSSWPL 168
L+ L+ V S K K++ + +L++ + E + SK + + L
Sbjct: 413 LEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAKQDKSKEAECKALQAEVQKLKNSL 472
Query: 169 DEGKKVKERFDEIFDADKYSDCLDR-------LKKIRKDYAQNLKLLENYATTVKAKQKE 221
+E K+ + E A + + C + L+ ++ + L L + A T++ Q+E
Sbjct: 473 EEAKQQERLAGEAPAAQQAAQCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRE 532
Query: 222 LEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFI-LLESQNQEKIDKRNEQIVETAKIAEI 280
L+ K+++ KE+ +E ++ + LE+ ++EK + + K+ ++
Sbjct: 533 LQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDM 592
Query: 281 ENITEVQTNEEAENATK--TILEKVESLKSDHKVQKSQADEEEKKAQGFVDECR 332
+ + Q E+ K L++ L D + Q ++ E EK +G ++ R
Sbjct: 593 LDRIKHQHREQGSIKCKLEEDLQEATKLLEDKREQLKKSKEHEKLMEGELEALR 646
>AY014284-1|AAK27309.1| 699|Homo sapiens nucleoporin NYD-SP7 protein.
Length = 699
Score = 52.0 bits (119), Expect = 1e-05
Identities = 75/401 (18%), Positives = 172/401 (42%), Gaps = 34/401 (8%)
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDT---EIPQLEKRIVDVDTQIKTLN-ETVEEITM 670
DL+R + ++D SL E++ ++T E LE+RI +++ + L+ E +E+++
Sbjct: 112 DLRRMTTERD------SLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSN 165
Query: 671 SLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
+ E T K+ M L R K + + E +++ + + +
Sbjct: 166 MTLMKETISTVEKE----MKSLAR-----KAMDTESELGRQKAENNSLRLLYENTEKDLS 216
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
D ++ ++ + ++ TQ+K+ ++K+ + +EE+ + D L + K+
Sbjct: 217 DTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLND---LAKEKEC 273
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK 850
LQ+ ++ E + E+ + +R EA V +
Sbjct: 274 LQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRRQ 333
Query: 851 VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
+ + E+ Q + RE + + ND L E+ + + Q L+KK++ +E+ ++
Sbjct: 334 LDETNDELAQ-----IARERDILAHDNDNLQEQFAKANQENQALSKKLNDTHNEL--NDI 386
Query: 911 YKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAEC 970
++ D NL + K + + + + ++ ++ E+L N++ N + + K E
Sbjct: 387 KQKVQDTNLEVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLEL 446
Query: 971 TGALSE---LKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
A +E LK+ + E+E+ L + E+ ++ ++ LH
Sbjct: 447 ITAEAEGNRLKEKVDSLNREVEQHL--NAERSYKSQISTLH 485
Score = 39.1 bits (87), Expect = 0.094
Identities = 47/294 (15%), Positives = 122/294 (41%), Gaps = 8/294 (2%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+L++ ++L + + ++D + ++ + E L K++ D ++ + + V++
Sbjct: 333 QLDETNDELAQIARERDILAHDNDNLQEQFAKANQENQALSKKLNDTHNELNDIKQKVQD 392
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ E + K + + +++ + +E Q ++ + L++ TA
Sbjct: 393 TNL---EVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELITA 449
Query: 728 KQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ-KKVQDIVNL 784
+ K+K+ +L V+ ++ ++ TL++ K +EEL Q +KV + +L
Sbjct: 450 EAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADL 509
Query: 785 EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV-VRRNRDLIEAGSAYIAK 843
+++ +E+ E A +E+ + R++ E S +
Sbjct: 510 SSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNLE 569
Query: 844 VEVAFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+ N+ K ++I Q K+ + E + A +K+ + + + R V+T+
Sbjct: 570 ALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQ 623
>AL139095-7|CAI16451.1| 847|Homo sapiens cancer antigen 1 protein.
Length = 847
Score = 52.0 bits (119), Expect = 1e-05
Identities = 94/455 (20%), Positives = 188/455 (41%), Gaps = 52/455 (11%)
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIE 674
D ++++ + +LNE + LK T Q E RI ++ L + V+E+ M +
Sbjct: 318 DWEQSAESLQPVQEDMALNEVLQKLKHTNRKQ-EVRIQELQCSNLYLEKRVKELQMKI-- 374
Query: 675 PEQKMTTAKQIHGDM-PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFK 733
T +Q+ D+ L ++E+ + K++ + E+ + L+ A
Sbjct: 375 ------TKQQVFIDVINKLKENVEEL--IEDKYKIILEKNDTKKTLQNLEEVLANTQKHL 426
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLY----EKKTKAKEELLNTQK----KVQDIVNLE 785
Q+ + ++ KK+ A+ LQ Y ++K K+ + L K K +++ L+
Sbjct: 427 QESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQ 486
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVE 845
+ KK+L+ A ++L+E+ + + ++ +E +++E
Sbjct: 487 QLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQ------KLEKENLEERQKLKSRLE 540
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT--LKD 903
+V++L + + KN+ + + + N+ KQ+ ++ Q K +T LKD
Sbjct: 541 KLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKD 600
Query: 904 EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKL 963
++ +EV K D+ + +T +N E+LN + + ++ S + L
Sbjct: 601 QL--EEVLKSDI-----TKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLAL 653
Query: 964 FQQKAECTGALSELKKSLKGFRNELEKSLS-KDIEKKFR-----EKMYELHVTKAID--- 1014
C ++ + K E EK L KD FR EK ++ H K ID
Sbjct: 654 MVGLLTCQDIINSDAEHFK----ESEKLLKHKDRITTFRELIAKEKAFQDHAIKVIDCDS 709
Query: 1015 ---KDIREYAVALDKCLMEFHREKMENINMIIREL 1046
K IR+ L L ++H E ++ +I +L
Sbjct: 710 DEAKSIRDVPTLLGAKLDKYH-SLNEELDFLITKL 743
>AL139095-5|CAI16449.1| 545|Homo sapiens cancer antigen 1 protein.
Length = 545
Score = 52.0 bits (119), Expect = 1e-05
Identities = 94/455 (20%), Positives = 188/455 (41%), Gaps = 52/455 (11%)
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIE 674
D ++++ + +LNE + LK T Q E RI ++ L + V+E+ M +
Sbjct: 16 DWEQSAESLQPVQEDMALNEVLQKLKHTNRKQ-EVRIQELQCSNLYLEKRVKELQMKI-- 72
Query: 675 PEQKMTTAKQIHGDM-PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFK 733
T +Q+ D+ L ++E+ + K++ + E+ + L+ A
Sbjct: 73 ------TKQQVFIDVINKLKENVEEL--IEDKYKIILEKNDTKKTLQNLEEVLANTQKHL 124
Query: 734 QKISTLRNRVKTTQKKLNAHNKKLQTLY----EKKTKAKEELLNTQK----KVQDIVNLE 785
Q+ + ++ KK+ A+ LQ Y ++K K+ + L K K +++ L+
Sbjct: 125 QESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQ 184
Query: 786 ESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVE 845
+ KK+L+ A ++L+E+ + + ++ +E +++E
Sbjct: 185 QLKKELEKATASALDLLKREKEAQEQEFLSLQEEFQ------KLEKENLEERQKLKSRLE 238
Query: 846 VAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT--LKD 903
+V++L + + KN+ + + + N+ KQ+ ++ Q K +T LKD
Sbjct: 239 KLLTQVRNLQFMSENERTKNIKLQQQINEVKNENAKLKQQVARSEEQNYVPKFETAQLKD 298
Query: 904 EIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKL 963
++ +EV K D+ + +T +N E+LN + + ++ S + L
Sbjct: 299 QL--EEVLKSDI-----TKDTKTTHSNLLPDCSPCEERLNPADIKRASQLASKMHSLLAL 351
Query: 964 FQQKAECTGALSELKKSLKGFRNELEKSLS-KDIEKKFR-----EKMYELHVTKAID--- 1014
C ++ + K E EK L KD FR EK ++ H K ID
Sbjct: 352 MVGLLTCQDIINSDAEHFK----ESEKLLKHKDRITTFRELIAKEKAFQDHAIKVIDCDS 407
Query: 1015 ---KDIREYAVALDKCLMEFHREKMENINMIIREL 1046
K IR+ L L ++H E ++ +I +L
Sbjct: 408 DEAKSIRDVPTLLGAKLDKYH-SLNEELDFLITKL 441
>AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FHA)
phosphopeptide binding domain 1 protein.
Length = 692
Score = 52.0 bits (119), Expect = 1e-05
Identities = 86/404 (21%), Positives = 160/404 (39%), Gaps = 19/404 (4%)
Query: 610 EKVTEDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIK-TLNETVEE 667
EK+ E L +E L + L KI L + E LE+ I + K TL E +
Sbjct: 7 EKLREHLAEKEKLNEERLEQEEKLKAKIRQLTE-EKAALEEYITQERNRAKETLEEERKR 65
Query: 668 IT-MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDV-DSEMTLDVA 725
+ + + +QK AK I + + ++E +T ++ E + ++ +S + +
Sbjct: 66 MQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQKEISESNIAYEKR 125
Query: 726 TAKQV--DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK-KVQDIV 782
AK+ K+K+ L NR+ +++L +K L K + A + TQK K + +
Sbjct: 126 KAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESL 185
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
E +L L + K + E + E Y
Sbjct: 186 KAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEYKE 245
Query: 843 KVEVAFNKVKSLDAEIQ---QHKKKNVPREMEKIQEANDKLMEKQKQI-----MTDRQVL 894
+++ + SL+ ++Q QH KK + E+ +++ + E++ Q MT+
Sbjct: 246 QIKQHAQTIVSLEEKLQKVTQHHKK-IEGEIATLKDNDPAPKEERPQDPLVAPMTESSAK 304
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKE 954
+ L D++ + K L + K + D+T + +L +LN K EL +
Sbjct: 305 DMAYEHLIDDLLAAQ--KEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNV 362
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
L+ +Q+K E +S L + LE++L EK
Sbjct: 363 VLVQQQSKELSVLKEKMAQMSSLVEKKDRELKALEEALRASQEK 406
Score = 35.1 bits (77), Expect = 1.5
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 5/141 (3%)
Query: 193 RLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK 252
R++++ + A+ ++ E+ K K KE + KK E ++ +K E++ K
Sbjct: 101 RVQELEERLARQKEISESNIAYEKRKAKEAMEKEKKKVQ--DLENRLTKQKEELELKEQK 158
Query: 253 FILLESQNQEKIDKRNE-QIVETAKIAEIENITEVQTNEEAE-NATKTILEKVES-LKSD 309
+L ++ + + E Q + + + E++ AE TKT + VE L
Sbjct: 159 EDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLILQ 218
Query: 310 HKVQKSQADEEEKKAQGFVDE 330
K+ K+ DE+E + GF +E
Sbjct: 219 QKMVKALQDEQESQRHGFEEE 239
>AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related
protein protein.
Length = 1820
Score = 52.0 bits (119), Expect = 1e-05
Identities = 87/488 (17%), Positives = 205/488 (42%), Gaps = 35/488 (7%)
Query: 503 LEAERKHIRESLNERRSELTKAEDKIYKACGT-----QPYDVTLSKYTTTVEKLQDEQNV 557
LE + I+ L + + EL K ++++ K Q ++ K T +++++ N+
Sbjct: 713 LELKFNQIKAELAKTKGELIKTKEELKKRENESDSLIQELKTSIKKIITQNQRIKELINI 772
Query: 558 LQSSMFIINKYKG--QLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVP-GKLEKVTE 614
+ IN+++ L +N+ CN + S + VP K+
Sbjct: 773 IDQKEDTINEFQNLKSLMENTF--KCNDKADTSS-LIINNKLICNETVEVPKDSKSKICS 829
Query: 615 DLQRASA---KKDEILSMK-SLNEKITTLKDTE-IPQLEKRIVDVDTQIKTLNETVEEIT 669
+ +R + ++DE + K S++ +D + ++ I +++ I+ L E E +
Sbjct: 830 ERKRVNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIE-DIRVLQENNEGLR 888
Query: 670 MSLIEPEQKMTTAKQIHGDM-PMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT-- 726
L+ E ++ K+ ++ + + QE+ KK + ++ + S + +A
Sbjct: 889 AFLLTIENELKNEKEEKAELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELH 948
Query: 727 ---AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN 783
+K + ++KI L N ++T + + + +++ ++ K + + +Q D++N
Sbjct: 949 VQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTKIDELRTLDSVSQISNIDLLN 1008
Query: 784 L--------EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN-RDLI 834
L E++ Q D E + + E + ++++
Sbjct: 1009 LRDLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIWEECKEIV 1068
Query: 835 EAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVL 894
+A S ++E +++ L AE++ +K +N + ++ + +D L EK+ I ++ L
Sbjct: 1069 KASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEEL 1128
Query: 895 TKKIDTLKDEIAKQEVYKR---DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELN 951
+K TL +I KR +L + KA+ + ++ + ++++
Sbjct: 1129 QEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDIL 1188
Query: 952 EKESLIIK 959
EKES+I+K
Sbjct: 1189 EKESIILK 1196
Score = 51.6 bits (118), Expect = 2e-05
Identities = 119/655 (18%), Positives = 257/655 (39%), Gaps = 30/655 (4%)
Query: 391 LNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIV 450
+N E QQ+ +K + E +K +++ A++++ +++EN + L+
Sbjct: 834 VNENELQQDEPPAKKGSIHVSSAITEDQKKSEEVRPNIAEIEDIRVLQENNEGLRAFLLT 893
Query: 451 LKNKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHI 510
++N+ K E E + + + E + + + H+
Sbjct: 894 IENELKNEKEEKA----ELNKQIVHFQQELSLSEKKNLTLSKEVQQIQSNYDIAIAELHV 949
Query: 511 RESLNERRSE-LTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYK 569
++S N+ + E + K ++I A + +V+ K T K+ DE L S I N
Sbjct: 950 QKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHT--KI-DELRTLDSVSQISNIDL 1006
Query: 570 GQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSM 629
L+D L N E+ ++ K ++ E + S
Sbjct: 1007 LNLRD-----LSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQEPNRENSFHSSIEAIW 1061
Query: 630 KSLNE--KITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHG 687
+ E K ++ K +I +LE++I + ++K + E + E + + K+
Sbjct: 1062 EECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKD--ENNRLKEKEHKNQDDLLKEKET 1119
Query: 688 DMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQ 747
+ L +QE K VT + V+ + L T +K KI L + TQ
Sbjct: 1120 LIQQLKEELQE-KNVTLDVQIQHV----VEGKRALSELTQGVTCYKAKIKELET-ILETQ 1173
Query: 748 KKLNAHNKKL-QTLYEKKT---KAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXX 803
K +H+ KL Q + EK++ K + L Q+ +QD V + +
Sbjct: 1174 KVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLT 1233
Query: 804 XXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKK 863
+ L +E+ E + + ++ + A SA ++ + + A++++ K
Sbjct: 1234 NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE-KL 1292
Query: 864 KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRK 923
+ ++++++Q+ + ++ K + L KK + E+ ++ + L + L +K
Sbjct: 1293 TDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQK 1352
Query: 924 AQTDITNWQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSL 981
+ I +++ +LN EK+ + L E+E ++Q ++ + K E L+ +
Sbjct: 1353 VEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKW 1412
Query: 982 KGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM 1036
K N+LE ++ K+ L + +++E + ++ EKM
Sbjct: 1413 KEKCNDLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKM 1467
Score = 46.4 bits (105), Expect = 6e-04
Identities = 90/431 (20%), Positives = 184/431 (42%), Gaps = 36/431 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++E++ + +++ A E+ K N + LK+ E + + + +T I+ L E ++E
Sbjct: 1077 QIEELEQQIEKLQA---EVKGYKDENNR---LKEKEHKNQDDLLKEKETLIQQLKEELQE 1130
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++L Q + K+ ++ + Y +IK + E K + +++ D+
Sbjct: 1131 KNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSH-SAKLEQDILE 1189
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL-- 784
+ + K L +K Q+ L K + L K+ K KEE+ +QD+ +L
Sbjct: 1190 KESIILK-----LERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQ 1244
Query: 785 --EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE ++ + + L+ L+ K E ++ + D +
Sbjct: 1245 LKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQK 1304
Query: 843 KVEVAFNKVKSLDAEIQQ-HKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+V V ++ K L +I + KKKN +E++ Q +L E+ + + + +
Sbjct: 1305 EVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVE-EAIQQYERA 1363
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--EELNE-KESLI 957
KD K+++ + D+ L + QT + +QD L KL + + EL + KE
Sbjct: 1364 CKDLNVKEKIIE-DMRMTL-EEQEQTQV----EQDQVLEAKLEEVERLATELEKWKEKCN 1417
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK---DIEKKFREKMYELHVTKAID 1014
+TK Q+ + +++ L ++EL++S K D +K EKM + K +
Sbjct: 1418 DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAE 1477
Query: 1015 ----KDIREYA 1021
K++++YA
Sbjct: 1478 NIRNKEMKKYA 1488
>BX537708-1|CAD97819.1| 1605|Homo sapiens hypothetical protein
protein.
Length = 1605
Score = 51.6 bits (118), Expect = 2e-05
Identities = 91/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + ++++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFQERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFQERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 33.1 bits (72), Expect = 6.2
Identities = 44/212 (20%), Positives = 91/212 (42%), Gaps = 8/212 (3%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E+ +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFQERIQALEEDLRE 301
>BX537421-1|CAD97663.1| 1204|Homo sapiens hypothetical protein
protein.
Length = 1204
Score = 51.6 bits (118), Expect = 2e-05
Identities = 91/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 126 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 183
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 184 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 243
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + ++++ +A EE + ++
Sbjct: 244 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFQERIQALEE--DLRE 301
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 302 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 343
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 344 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 403
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 404 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 463
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 464 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 516
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 517 ELRSEGLITEKC 528
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 188 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 247
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 248 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFQERIQALEEDL 299
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 300 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 357
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 358 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 416
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 417 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 474
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 475 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 504
Score = 33.1 bits (72), Expect = 6.2
Identities = 44/212 (20%), Positives = 91/212 (42%), Gaps = 8/212 (3%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 95 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 153
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 154 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 213
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 214 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 269
Query: 988 LEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E+ +A+++D+RE
Sbjct: 270 KERETEAAQMEHQKERNSFQERIQALEEDLRE 301
>BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein.
Length = 498
Score = 51.6 bits (118), Expect = 2e-05
Identities = 83/424 (19%), Positives = 184/424 (43%), Gaps = 26/424 (6%)
Query: 641 DTEIPQLEKRIVDVDTQIKTLNETVEEIT----MSLIEPEQKMTTAKQIHGDMPMLDRYI 696
+ E + E + + + ++ E EE+ M E E +++ + ++ L++
Sbjct: 1 EAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSK 60
Query: 697 QEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKK 756
+ ++T ++ + E+ D + + T D +V+ + ++ ++ ++
Sbjct: 61 RALETQMEEMKTQLEELED-ELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQ 119
Query: 757 LQT-LYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVA 815
LQ L+E +T+ ++E LE K L+ + L+
Sbjct: 120 LQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ 179
Query: 816 LKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQE 875
+K+ + + E R +RD I A + K K KSL+A++ Q ++ E + Q
Sbjct: 180 MKD-FQRELEDARASRDEIFATAKENEK------KAKSLEADLMQLQEDLAAAERARKQA 232
Query: 876 ANDK--LMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTD-ITNWQ 932
+K L E+ ++ R L + L+ IA+ E +L++ +A +D +
Sbjct: 233 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLE---EELEEEQGNMEAMSDRVRKAT 289
Query: 933 KQDDEL-NEKLNGINKEELNEK-ESLIIKQTKLFQQKA-ECTGAL-SELKKSLKGFRNEL 988
+Q ++L NE + + NE + +Q K + K E GA+ S+ K ++ ++
Sbjct: 290 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI 349
Query: 989 EKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVAL--DKCLMEFHREKMENINMIIREL 1046
+ L + +E++ REK K DK ++E + + ++ + E ++E+ E N +++L
Sbjct: 350 AQ-LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQL 408
Query: 1047 WRKI 1050
R++
Sbjct: 409 KRQL 412
Score = 45.6 bits (103), Expect = 0.001
Identities = 51/281 (18%), Positives = 127/281 (45%), Gaps = 24/281 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
+++ +L+ A A +DEI + NEK + ++ QL++ + + K + EE
Sbjct: 179 QMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEE 238
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVAT 726
+ L A + G + D + + + E ++E+ G++++ + AT
Sbjct: 239 LAEEL---------ASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKAT 289
Query: 727 AKQVDFKQKISTLRN---RVKTTQKKLNAHNKKLQT-LYEKKTKAKEELLNTQKKVQDIV 782
+ +++T R+ + ++ +++L NK+L++ L+E + K + +T I
Sbjct: 290 QQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKST------IA 343
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE---KIEAKTEVVRRNRDLIEAGSA 839
LE QL+ ++ + LKE ++E + ++ + ++ E G+A
Sbjct: 344 ALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNA 403
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKL 880
+ +++ + + I +++K + RE+++ E+N+ +
Sbjct: 404 RVKQLKRQLEEAEEESQRINANRRK-LQRELDEATESNEAM 443
>BC028366-1|AAH28366.1| 698|Homo sapiens testis specific, 10 protein.
Length = 698
Score = 51.6 bits (118), Expect = 2e-05
Identities = 74/401 (18%), Positives = 172/401 (42%), Gaps = 34/401 (8%)
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDT---EIPQLEKRIVDVDTQIKTLN-ETVEEITM 670
DL+R + ++D SL E++ ++T E LE+RI +++ + L+ E +E+++
Sbjct: 111 DLRRMTTERD------SLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSN 164
Query: 671 SLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQV 730
+ E T K+ M L R K + + E +++ + + +
Sbjct: 165 MTLMKETISTVEKE----MKSLAR-----KAMDTESELGRQKAENNSLRLLYENTEKDLS 215
Query: 731 DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQ 790
D ++ ++ + ++ TQ+K+ ++K+ + +EE+ + D L + K+
Sbjct: 216 DTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLND---LAKEKEC 272
Query: 791 LQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNK 850
+Q+ ++ E + E+ + +R EA V +
Sbjct: 273 MQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVSRMRRQ 332
Query: 851 VKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV 910
+ + E+ Q + RE + + ND L E+ + + Q L+KK++ +E+ ++
Sbjct: 333 LDETNDELAQ-----IARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNEL--NDI 385
Query: 911 YKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAEC 970
++ D NL + K + + + + ++ ++ E+L N++ N + + K E
Sbjct: 386 KQKVQDTNLEVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLEL 445
Query: 971 TGALSE---LKKSLKGFRNELEKSLSKDIEKKFREKMYELH 1008
A +E LK+ + E+E+ L + E+ ++ ++ LH
Sbjct: 446 ITAEAEGNRLKEKVDSLNREVEQHL--NAERSYKSQISTLH 484
Score = 40.7 bits (91), Expect = 0.031
Identities = 50/295 (16%), Positives = 124/295 (42%), Gaps = 10/295 (3%)
Query: 608 KLEKVTEDLQRASAKKDEIL-SMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVE 666
+L++ ++L + + ++D + +L E+ K E L K++ D ++ + + V+
Sbjct: 332 QLDETNDELAQIARERDILAHDNDNLQEQFAKAKQ-ENQALSKKLNDTHNELNDIKQKVQ 390
Query: 667 EITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ + E + K + + +++ + +E Q ++ + L++ T
Sbjct: 391 DTNL---EVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKLELIT 447
Query: 727 AKQVD--FKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQ-KKVQDIVN 783
A+ K+K+ +L V+ ++ ++ TL++ K +EEL Q +KV + +
Sbjct: 448 AEAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALAD 507
Query: 784 LEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEV-VRRNRDLIEAGSAYIA 842
L +++ +E+ E A +E+ + R++ E S
Sbjct: 508 LSSTRELCIKLDSSKELLNRQLVAKDQEIEMRENELDSAHSEIELLRSQMANERISMQNL 567
Query: 843 KVEVAFNKVKSLDAEIQ-QHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
+ + N+ K ++I Q K+ + E + A +K+ + + + R V+T+
Sbjct: 568 EALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQFRNVVTQ 622
>AM177178-1|CAJ45482.1| 725|Homo sapiens kinesin-like protein
KIF3Abeta protein.
Length = 725
Score = 51.6 bits (118), Expect = 2e-05
Identities = 50/198 (25%), Positives = 91/198 (45%), Gaps = 14/198 (7%)
Query: 858 IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDD 917
I++ K +P + K + + DK++E Q +I +R+ L K+D ++E K
Sbjct: 423 IEKPLDKFLPNQAGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAE------ 476
Query: 918 NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSEL 977
L K + D+ Q++ L EKL+ + K+ + L+ K + + E L E
Sbjct: 477 ---LEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLEESNMELEER 533
Query: 978 KKSLKGFRNELEKSLSK--DIEKKFREKMYELH-VTKAIDKDIREYAVALDKC--LMEFH 1032
+K + R ELE+ + DIE+K+ E TK + K A + L + H
Sbjct: 534 RKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEH 593
Query: 1033 REKMENINMIIRELWRKI 1050
+ ++E + IR+L R++
Sbjct: 594 QREIEGLLENIRQLSREL 611
Score = 37.5 bits (83), Expect = 0.29
Identities = 19/80 (23%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Query: 388 ENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQT-AKLKEKEMIEENLKTKEK 446
E+ + +EE ++ + + +E+ EQE ++ +K T LQ++ K K+ + + L +
Sbjct: 525 ESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKS 584
Query: 447 QLIVLKNKHKTALMELLGNV 466
++ L+ +H+ + LL N+
Sbjct: 585 EMADLQQEHQREIEGLLENI 604
>AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein.
Length = 1642
Score = 51.6 bits (118), Expect = 2e-05
Identities = 118/604 (19%), Positives = 266/604 (44%), Gaps = 62/604 (10%)
Query: 393 IEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
+E+ ++ N +++ +++ E ++EL+ KI + +K+T +LK+K + L + ++ IV K
Sbjct: 322 MEQDKKVENSNKEEIQEKETIIEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQK 381
Query: 453 NKHKTALMELLGNVPEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIRE 512
N+ + L N +K+ + E ++ E + E
Sbjct: 382 NQEIKNMKLELTNSKQKE------RQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRME 435
Query: 513 SLNERRSELTKAE-DKIYKACGTQPYDVTLSKYTTTVEKLQ-----DEQNVLQS-SMFII 565
+R+ E +AE D++Y Q + ++ +E+++ + +N L+S S +
Sbjct: 436 QETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITV 495
Query: 566 NKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL-QRASAKKD 624
N+ + +L + + L N ++ + + L++ EDL + S ++
Sbjct: 496 NEDQIKLMNVAINEL-NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 554
Query: 625 EI-LSMKSLNEKITTLKD-----TEIPQLEKRIVDVDTQIKTL------NETVEEITMSL 672
+I + +++ E+ + L + + + L+ IV K L T +I + +
Sbjct: 555 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 614
Query: 673 IEPEQKMTTAKQIHGDMPMLDRY-IQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQ-- 729
+E E+ + L+R Q + + ++ +KE D++ E +++ K
Sbjct: 615 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKE---DLEIEHRINIEKLKDNL 671
Query: 730 -VDFKQKISTLRN----RVKTTQ-KKLNAHNKKLQTLYE-KKTKAKEELLNTQKKVQDIV 782
+ +KQ+I L+N +++T Q +K N K+ Q + E K K ++ L K + +
Sbjct: 672 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 731
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
+ E +K+++ E+ LK ++ K ++ + DL E + A
Sbjct: 732 QINELQKEIE---ILRQEEKEKGTLEQEVQELQLKTELLEK-QMKEKENDLQEKFAQLEA 787
Query: 843 KVEVAFNKVKSLDAEIQQHKKKNVPRE---MEKIQ-EANDKLMEKQKQIM-TDRQVLTKK 897
+ + ++ K+L+ ++ H + ++ I+ ++ D + EK+ +I+ + + L ++
Sbjct: 788 ENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQ 847
Query: 898 IDTLKDEIAKQ-----------EVYKRDL-DDNLCLRKAQTDITNWQ-KQDDELNEKLNG 944
L +EI KQ EV ++L ++ CL K + D+ + + KQ+ E KL
Sbjct: 848 CIQLNEEIEKQRNTFSFAEKNFEVNYQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKA 907
Query: 945 INKE 948
+N+E
Sbjct: 908 LNEE 911
Score = 50.4 bits (115), Expect = 4e-05
Identities = 84/434 (19%), Positives = 190/434 (43%), Gaps = 34/434 (7%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE--KRIVDVDTQIKTLNETVEE 667
+K+ +LQ +K++ +K++ ++T K E E K+++ +++ N +
Sbjct: 368 DKLLGELQEQIVQKNQ--EIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQ 425
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+++ ++ T K + + Y Q+I V K E +++ ++ T
Sbjct: 426 FETDIVQRMEQETQRKLEQLRAELDEMYGQQI--VQMKQELIRQHMAQMEEMKTRHKGEM 483
Query: 728 KQ-VDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEEL-------LNTQKKVQ 779
+ + I+ +++K +N N KLQ +K K KEEL Q++++
Sbjct: 484 ENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLE 543
Query: 780 DIV-NLEESKKQLQ------SDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRD 832
D+V L S++Q+Q ++ + L+ + E++ E+ ++
Sbjct: 544 DLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEA 603
Query: 833 LIEAGSAYIAKVEVAFNKV-----KSLDAEIQQHKKKNVPREMEKIQEANDKL-MEKQKQ 886
+ + +E N V +S +AE+++ + + + E++ + + L +E +
Sbjct: 604 EVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRIN 663
Query: 887 IMTDRQVL----TKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKL 942
I + L ++ID L++E++++ + DNL ++ Q I K D L + L
Sbjct: 664 IEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQL-ILEISKLKD-LQQSL 721
Query: 943 NGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
EE+ + + + K+ ++ +Q+ + G L + + L+ + EL + K+ E +E
Sbjct: 722 VNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQ-LKTELLEKQMKEKENDLQE 780
Query: 1003 KMYELHVTKAIDKD 1016
K +L +I KD
Sbjct: 781 KFAQLEAENSILKD 794
Score = 43.6 bits (98), Expect = 0.004
Identities = 82/436 (18%), Positives = 187/436 (42%), Gaps = 39/436 (8%)
Query: 384 HKQAENELNIEECQQEINEDEKAVEQYEQEMDEL-SQKITKLQKQTAKLKEKEMIEENLK 442
HK ++ E +I + ++ E ++ +EQ E+DE+ Q+I +++++ + +M E +
Sbjct: 421 HKDSQFETDIVQRMEQ--ETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTR 478
Query: 443 TKEKQLIVLKNKHKTALME---LLGNVPEKDFAVTI---NKFECEVRNEVXXXXXXXXXX 496
K + L++ + E L NV + + + N + +++ E+
Sbjct: 479 HKGEMENALRSYSNITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCAL 538
Query: 497 XXXXXXLEAERKHIRESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQN 556
L E RE + R + + E K+ +A + L + + + E
Sbjct: 539 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELE 598
Query: 557 VLQSSMFIINKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDL 616
+ + K K ++ + + +R ES+ + +L K+ EDL
Sbjct: 599 LKHEAEVTNYKIKLEMLEKEKNAVLDR--MAESQEAELERLRTQLLFSHEEELSKLKEDL 656
Query: 617 Q---RASAKK----------DEILSMKS-LNEKITTL---KDTEIPQLEKRIVDV----D 655
+ R + +K +I +++ +++KI T+ KD I + + I+++ D
Sbjct: 657 EIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKD 716
Query: 656 TQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFE-AVKEQCG 714
Q +N EE+T+ + E ++++ +Q + L++ +QE++ T+ E +KE+
Sbjct: 717 LQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKEN 776
Query: 715 DVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNT 774
D+ + A+ K + TL + +K + ++L L K+K+K+ +
Sbjct: 777 DLQEKFA--QLEAENSILKDEKKTLEDMLKIHTPV--SQEERLIFLDSIKSKSKDSV--W 830
Query: 775 QKKVQDIVNLEESKKQ 790
+K+++ ++ E KQ
Sbjct: 831 EKEIEILIEENEDLKQ 846
Score = 40.3 bits (90), Expect = 0.041
Identities = 43/166 (25%), Positives = 76/166 (45%), Gaps = 15/166 (9%)
Query: 852 KSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVY 911
+ L + QQ + R A D L KQ QI+T +Q L ++ L+D K+E
Sbjct: 248 QKLQIQFQQLQASETLRNSTHSSTAADLLQAKQ-QILTHQQQLEEQDHLLEDYQKKKE-- 304
Query: 912 KRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK-QTKLFQQKAEC 970
D + + Q I ++ + D+ K+ NKEE+ EKE++I + TK+ +++ +
Sbjct: 305 ----DFTMQISFLQEKIKVYEMEQDK---KVENSNKEEIQEKETIIEELNTKIIEEEKKT 357
Query: 971 TGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKD 1016
ELK L L + + ++K K +L +T + K+
Sbjct: 358 L----ELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKE 399
Score = 34.3 bits (75), Expect = 2.7
Identities = 30/151 (19%), Positives = 76/151 (50%), Gaps = 7/151 (4%)
Query: 180 EIFDADKYSDCLDRLKKIRKDYAQNLK--LLENYATTVKAKQKELEDSYKKNTSFNKEEE 237
E+ + +K + LDR+ + ++ + L+ LL ++ + +++LE ++ N K+
Sbjct: 613 EMLEKEKNA-VLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNL 671
Query: 238 KIANEKSSNEIEYNKFILLESQNQEK---IDKRNEQIVETAKIAEIENITEVQTNEEAEN 294
I ++ + ++ +E+ EK I K+N+ I+E +K+ +++ +EE
Sbjct: 672 GIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTL 731
Query: 295 ATKTILEKVESLKSDHKVQKSQADEEEKKAQ 325
+ +++E L+ + K +K ++E ++ Q
Sbjct: 732 QINELQKEIEILRQEEK-EKGTLEQEVQELQ 761
>AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein.
Length = 704
Score = 51.6 bits (118), Expect = 2e-05
Identities = 86/404 (21%), Positives = 160/404 (39%), Gaps = 19/404 (4%)
Query: 610 EKVTEDLQRASAKKDEILSMKS-LNEKITTLKDTEIPQLEKRIVDVDTQIK-TLNETVEE 667
EK+ E L +E L + L KI L + E LE+ I + K TL E +
Sbjct: 19 EKLREHLAEKEKLNEERLEQEEKLKAKIRQLTE-EKAALEEYITQERNRAKETLEEERKR 77
Query: 668 IT-MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDV-DSEMTLDVA 725
+ + + +QK AK I + + ++E +T ++ E + ++ +S + +
Sbjct: 78 MQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQKEISESNIAYEKR 137
Query: 726 TAKQV--DFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK-KVQDIV 782
AK+ K+K+ L NR+ +++L +K L K + A + TQK K + +
Sbjct: 138 KAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESL 197
Query: 783 NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
E +L L + K + E + E Y
Sbjct: 198 KAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFGEEIMEYKE 257
Query: 843 KVEVAFNKVKSLDAEIQ---QHKKKNVPREMEKIQEANDKLMEKQKQI-----MTDRQVL 894
+++ + SL+ ++Q QH KK + E+ +++ + E++ Q MT+
Sbjct: 258 QIKQHAQTIVSLEEKLQKVTQHHKK-IEGEIATLKDNDPAPKEERPQDPLVAPMTESSAK 316
Query: 895 TKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKE 954
+ L D++ + K L + K + D+T + +L +LN K EL +
Sbjct: 317 DMAYEHLIDDLLAAQ--KEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNV 374
Query: 955 SLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
L+ +Q+K E +S L + LE++L EK
Sbjct: 375 VLVQQQSKELSVLKEKMAQMSSLVEKKDRELKALEEALRASQEK 418
Score = 34.7 bits (76), Expect = 2.0
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 5/141 (3%)
Query: 193 RLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNK 252
R++++ + A+ ++ E+ K K KE + KK E ++ +K E++ K
Sbjct: 113 RVQELEERLARQKEISESNIAYEKRKAKEAMEKEKKKVQ--DLENRLTKQKEELELKEQK 170
Query: 253 FILLESQNQEKIDKRNE-QIVETAKIAEIENITEVQTNEEAE-NATKTILEKVES-LKSD 309
+L ++ + + E Q + + + E++ AE TKT + VE L
Sbjct: 171 EDVLNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLILQ 230
Query: 310 HKVQKSQADEEEKKAQGFVDE 330
K+ K+ DE+E + GF +E
Sbjct: 231 QKMVKALQDEQESQRHGFGEE 251
>AB046853-1|BAB13459.2| 1852|Homo sapiens KIAA1633 protein protein.
Length = 1852
Score = 51.6 bits (118), Expect = 2e-05
Identities = 91/432 (21%), Positives = 174/432 (40%), Gaps = 41/432 (9%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKS-LNEKITTLKDT---EIPQLEKRIVDVDTQIKTLNE 663
K K E L A A EI +K +K+ ++D I LEK + +++
Sbjct: 164 KASKAVESL--AEAGGSEIQRVKEDARKKVQQVEDLLTKRILLLEKDVTAAQAELEKAFA 221
Query: 664 TVEEITMSLIEPEQKMTTAKQIH-GDMPML------DRYIQEIKTVTKKFEAVKEQCGDV 716
E + E K++ K++H GD+ M DR I+E+K K EA+ + +
Sbjct: 222 GTETEKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEE 281
Query: 717 DSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQK 776
S+M + + + R + + ++K + ++++ +A EE + ++
Sbjct: 282 KSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKERNSFQERIQALEE--DLRE 339
Query: 777 KVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEA 836
K ++I E K L+ D AI L +ALK K E K E + IE
Sbjct: 340 KEREIAT--EKKNSLKRD------------KAIQGLTMALKSK-EKKVEELNSE---IEK 381
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTK 896
SA AK A K ++ + + + + + + + + K + R+ + K
Sbjct: 382 LSAAFAKAREALQKAQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKK 441
Query: 897 KIDTLKDEIAKQEVYKRDLDD-NLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKES 955
L D ++E ++DL++ + K I + + + ++L ++N K N +S
Sbjct: 442 ITQELSDLQQERERLEKDLEEAHREKSKGDCTIRDLRNEVEKLRNEVNEREKAMENRYKS 501
Query: 956 LIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDK 1015
L+ + K + ++ K L N+ + L K EK ++ A D
Sbjct: 502 LLSESNKKLHNQ-------EQVIKHLTESTNQKDVLLQKFNEKDLEVIQQNCYLMAAEDL 554
Query: 1016 DIREYAVALDKC 1027
++R + +KC
Sbjct: 555 ELRSEGLITEKC 566
Score = 35.5 bits (78), Expect = 1.2
Identities = 61/330 (18%), Positives = 135/330 (40%), Gaps = 37/330 (11%)
Query: 734 QKISTLRNRVKTTQ-KKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQL 791
+K LR K ++ KK++ + + + ++K + EEL + K + ++ L+E K Q+
Sbjct: 226 EKALRLRLESKLSEMKKMHEGDLAMALVLDEKDRLIEELKLSLKSKEALIQCLKEEKSQM 285
Query: 792 QSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKV 851
+ L A +E+ E +TE + + +++ +++ +
Sbjct: 286 ACP------DENVSSGELRGLCAAPREEKERETEAAQMEHQ--KERNSFQERIQALEEDL 337
Query: 852 KSLDAEIQQHKKKNVPREM-------------EKIQEANDKLMEKQKQIMTDRQVLTKKI 898
+ + EI KK ++ R+ +K++E N ++ + R+ L K
Sbjct: 338 REKEREIATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSEIEKLSAAFAKAREALQK-- 395
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKA-QTDITNWQKQDDELNEKLNGINKE--ELNEKES 955
E E Y+ L L A ++ ++ L + I +E +L ++
Sbjct: 396 -AQTQEFQGSEDYETALSGKEALSAALRSQNLTKSTENHRLRRSIKKITQELSDLQQERE 454
Query: 956 LI---IKQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYELHV 1009
+ +++ + K +CT + +L+ ++ RN E EK++ + E +LH
Sbjct: 455 RLEKDLEEAHREKSKGDCT--IRDLRNEVEKLRNEVNEREKAMENRYKSLLSESNKKLHN 512
Query: 1010 TKAIDKDIREYAVALDKCLMEFHREKMENI 1039
+ + K + E D L +F+ + +E I
Sbjct: 513 QEQVIKHLTESTNQKDVLLQKFNEKDLEVI 542
Score = 33.1 bits (72), Expect = 6.2
Identities = 44/212 (20%), Positives = 91/212 (42%), Gaps = 8/212 (3%)
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
P E K IE K EV R+L E I + + ++ +EIQ+ K++ +++
Sbjct: 133 PTEHIYKTNIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQR-VKEDARKKV 191
Query: 871 EKIQE-ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDIT 929
+++++ +++ +K + + L K + E A + + L + + + +
Sbjct: 192 QQVEDLLTKRILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHEGDLAMA 251
Query: 930 NWQKQDDELNEKLNGINKEELNEKESLI--IKQTKLFQQKAECTGALSELKKSLKGFRNE 987
+ D L E+L K L KE+LI +K+ K + + EL+ R E
Sbjct: 252 LVLDEKDRLIEEL----KLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREE 307
Query: 988 LEKSLSKDIEKKFREKMYELHVTKAIDKDIRE 1019
E+ + +E+ +A+++D+RE
Sbjct: 308 KERETEAAQMEHQKERNSFQERIQALEEDLRE 339
>Z97054-3|CAI42646.1| 1233|Homo sapiens structural maintenance of
chromosomes 1A protein.
Length = 1233
Score = 51.2 bits (117), Expect = 2e-05
Identities = 77/367 (20%), Positives = 151/367 (41%), Gaps = 27/367 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKT 443
K NE+ IE+ +E+ K +E+ ++ MD++ ++ + +K+ K ++E++ IE+ +K
Sbjct: 227 KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE 286
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXX 502
K+ +L N+ + ++ N K + K + +
Sbjct: 287 KDSEL----NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 503 LEAERKHIRESLNERRS----ELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQNV 557
+E R+ E + E +LT E+++ K + + +EK +Q
Sbjct: 343 VEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKA 402
Query: 558 LQSSMFIINKYKGQLKDNSCCPLCNRGFENES--EXXXXXXXXXXXXMNVPGKLE-KVTE 614
Q + + + K + + L EN+ E + KLE ++TE
Sbjct: 403 DQDRLDLEERKKVETEAKIKQKL-REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTE 461
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE----KRIVDVDTQIKTLNE-TVEEIT 669
+++ A + DEI K LN+ + L D I + E +R ++ IK L +V
Sbjct: 462 EVEMAKRRIDEI--NKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRL 519
Query: 670 MSLIEPEQK---MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ L +P QK + K + +M + + KT + +KEQ G+ ++ + LD
Sbjct: 520 IDLCQPTQKKYQIAVTKVLGKNMDAI--IVDSEKTGRDCIQYIKEQRGEPETFLPLDYLE 577
Query: 727 AKQVDFK 733
K D K
Sbjct: 578 VKPTDEK 584
Score = 48.0 bits (109), Expect = 2e-04
Identities = 56/301 (18%), Positives = 127/301 (42%), Gaps = 17/301 (5%)
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN-AHNKKLQ 758
K V K E + ++ +M A+ + + L+ R+K +Q L + L
Sbjct: 669 KAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLA 728
Query: 759 TLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
++K+K + EL N ++ DI + +S+++ D E+ ++
Sbjct: 729 LNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRN 788
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
E + E V+R + IAK + F K+ +K + + +K+
Sbjct: 789 IREFEEEKVKRQNE--------IAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQ 840
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL 938
+ + + +I ++ + + + + +A+ + DL + +K++ + N + + E+
Sbjct: 841 TVKKDENEIEKLKKEEQRHMKIIDETMAQLQ----DLKNQHLAKKSEVNDKNHEME--EI 894
Query: 939 NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+KL G NKE + ++ + +TKL Q++++ L K ++ + L K DI +
Sbjct: 895 RKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACK--MQDIKLPLSKGTMDDISQ 952
Query: 999 K 999
+
Sbjct: 953 E 953
Score = 47.6 bits (108), Expect = 3e-04
Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 21/221 (9%)
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
A++Q K E+E I++ N +L K K+I D+ K++D ++DE+ ++ K++L
Sbjct: 219 AQVQLQLFKLYHNEVE-IEKLNKELASKNKEIEKDK----KRMDKVEDELKEK---KKEL 270
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
+R+ Q +++D ELN+K + + KE+ K KL K A
Sbjct: 271 --GKMMREQQQIEKEIKEKDSELNQK----RPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Query: 976 ELKKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHR 1033
KK KG +ELEK + + ++F E+M E ++ D + E V K
Sbjct: 325 HYKKR-KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQV---KKYHRLKE 380
Query: 1034 EKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERR 1074
E + + +EL K R D + E VE+E +
Sbjct: 381 EASKRAATLAQEL-EKFNRDQKADQDRLDLEERKKVETEAK 420
Score = 41.9 bits (94), Expect = 0.013
Identities = 86/420 (20%), Positives = 175/420 (41%), Gaps = 43/420 (10%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++ K ED Q +K I + + ++ D +L+ +V Q++ E
Sbjct: 174 EMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + + E K+I D +D+ E+K K+ + + ++ E+ +
Sbjct: 233 VEIEKLNKELASKN-KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
Q Q I N KKL A K LQ + K K ++ +K +++++E++
Sbjct: 292 NQKR-PQYIKAKENTSHKI-KKLEAAKKSLQNAQKHYKKRKGDMDELEK---EMLSVEKA 346
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+++ + +T E +K+ K E +R +A +A+
Sbjct: 347 RQEFEERMEEESQSQGRD---LTLEENQVKKYHRLKEEASKR--------AATLAQELEK 395
Query: 848 FNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
FN+ + D + + ++K V E KI++ ++ E QK+I + L + I T K +
Sbjct: 396 FNRDQKADQDRLDLEERKKVETEA-KIKQKLREIEENQKRI----EKLEEYITTSKQSLE 450
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ 966
+Q+ + +L + + + K + D N ELN+ + + ++ +ES +Q Q+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEIN-----KELNQVMEQLGDARIDRQES--SRQ----QR 499
Query: 967 KAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
KAE + +K+ G L + +KK Y++ VTK + K++ V +K
Sbjct: 500 KAE---IMESIKRLYPGSVYGRLIDLCQPTQKK-----YQIAVTKVLGKNMDAIIVDSEK 551
Score = 39.9 bits (89), Expect = 0.054
Identities = 57/247 (23%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 85 KIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHE 144
K + KD +L R + A K + L++ ++ + K R D+D L E
Sbjct: 282 KEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNA--QKHYKKRKGDMDELEKE 339
Query: 145 ELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQN 204
L V KA +E S +G+ + +++ KY + K AQ
Sbjct: 340 MLSVEKARQEFEERMEEESQS----QGRDLTLEENQV---KKYHRLKEEASKRAATLAQE 392
Query: 205 LKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKI 264
L E + KA Q L+ +K + E KI ++ EIE +NQ++I
Sbjct: 393 L---EKFNRDQKADQDRLDLEERKKV---ETEAKI--KQKLREIE---------ENQKRI 435
Query: 265 DKRNEQIVETAKIAEIENITEVQTNEEAENATKTI------LEKVESLKSDHKVQKSQAD 318
+K E I + + E + E + EE E A + I L +V D ++ + ++
Sbjct: 436 EKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESS 495
Query: 319 EEEKKAQ 325
+++KA+
Sbjct: 496 RQQRKAE 502
Score = 37.9 bits (84), Expect = 0.22
Identities = 48/223 (21%), Positives = 107/223 (47%), Gaps = 17/223 (7%)
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
E+ +N++ IE + KVE +++K E+ + ++ E E I+E + +L +K+
Sbjct: 241 ELASKNKE-IEKDKKRMDKVE---DELKEKKKELGKMMREQQQIEKE-IKEKDSELNQKR 295
Query: 885 KQIMTDRQVLT---KKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE 940
Q + ++ + KK++ K + Q+ YK+ D L K + +++ +E E
Sbjct: 296 PQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Query: 941 KLNGINKEELNEKESLIIKQTKLFQQKAECTGALS-ELKKSLKGF-----RNELEKSLSK 994
+ + +L +E+ + K +L ++ ++ L+ EL+K + R +LE+
Sbjct: 356 EESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKV 415
Query: 995 DIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKME 1037
+ E K ++K+ E+ + + + EY + L E ++K+E
Sbjct: 416 ETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEE--QKKLE 456
Score = 33.9 bits (74), Expect = 3.5
Identities = 65/363 (17%), Positives = 142/363 (39%), Gaps = 33/363 (9%)
Query: 395 ECQQEINEDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEK----EMIEENLKTKEKQ 447
E QE ++ +K + + E++ + I +K+ + KE+ + +++ + + Q
Sbjct: 163 ELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQ 222
Query: 448 LIVLKNKHKTALMELLGN-VPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXXLEA 505
L + K H +E L + K+ + +K + V +E+ +E
Sbjct: 223 LQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEK 282
Query: 506 ERKHIRESLNERRSELTKA-EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFI 564
E K LN++R + KA E+ +K + +L +K + + + L+ M
Sbjct: 283 EIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 565 INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD 624
+ K + + ++ E ES+ N K ++ E+ + +A
Sbjct: 343 VEKARQEFEER---------MEEESQSQGRDLTLEE---NQVKKYHRLKEEASKRAATLA 390
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ 684
+ L + ++K + E++ V+ + +IK +EE + + E+ +TT+KQ
Sbjct: 391 QELEKFNRDQKAD---QDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQ 447
Query: 685 IHGDMPMLDRYIQE--------IKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI 736
+ L+ + E I + K+ V EQ GD + ++ + + I
Sbjct: 448 SLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESI 507
Query: 737 STL 739
L
Sbjct: 508 KRL 510
>U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1
protein.
Length = 753
Score = 51.2 bits (117), Expect = 2e-05
Identities = 77/408 (18%), Positives = 169/408 (41%), Gaps = 15/408 (3%)
Query: 635 KITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDR 694
K ++ K +I +LE++I + ++K + E + E + + K+ + L
Sbjct: 2 KASSKKSHQIEELEQQIEKLQAEVKGYKD--ENNRLKEKEHKNQDDLLKEKETLIQQLKE 59
Query: 695 YIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHN 754
+QE K VT + V+ + L T +K KI L + TQK +H+
Sbjct: 60 ELQE-KNVTLDVQIQHV----VEGKRALSELTQGVTCYKAKIKELET-ILETQKVERSHS 113
Query: 755 KKL-QTLYEKKT---KAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAIT 810
KL Q + EK++ K + L Q+ +QD V + + +
Sbjct: 114 AKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMK 173
Query: 811 PLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREM 870
L +E+ E + + ++ + A SA ++ + + A++++ K + +++
Sbjct: 174 HLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKE-KLTDAKKQI 232
Query: 871 EKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITN 930
+++Q+ + ++ K + L KK + E+ ++ + L + L +K + I
Sbjct: 233 KQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQ 292
Query: 931 WQKQDDELN--EKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNEL 988
+++ +LN EK+ + L E+E ++Q ++ + K E L+ + K N+L
Sbjct: 293 YERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDL 352
Query: 989 EKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKM 1036
E ++ K+ L + +++E + ++ EKM
Sbjct: 353 ETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKM 400
Score = 46.4 bits (105), Expect = 6e-04
Identities = 90/431 (20%), Positives = 184/431 (42%), Gaps = 36/431 (8%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++E++ + +++ A E+ K N + LK+ E + + + +T I+ L E ++E
Sbjct: 10 QIEELEQQIEKLQA---EVKGYKDENNR---LKEKEHKNQDDLLKEKETLIQQLKEELQE 63
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPM-LDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
++L Q + K+ ++ + Y +IK + E K + +++ D+
Sbjct: 64 KNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSH-SAKLEQDILE 122
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNL-- 784
+ + K L +K Q+ L K + L K+ K KEE+ +QD+ +L
Sbjct: 123 KESIILK-----LERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQ 177
Query: 785 --EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIA 842
EE ++ + + L+ L+ K E ++ + D +
Sbjct: 178 LKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQK 237
Query: 843 KVEVAFNKVKSLDAEIQQ-HKKKN-VPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+V V ++ K L +I + KKKN +E++ Q +L E+ + + + +
Sbjct: 238 EVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVE-EAIQQYERA 296
Query: 901 LKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINK--EELNE-KESLI 957
KD K+++ + D+ L + QT + +QD L KL + + EL + KE
Sbjct: 297 CKDLNVKEKIIE-DMRMTL-EEQEQTQV----EQDQVLEAKLEEVERLATELEKWKEKCN 350
Query: 958 IKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSK---DIEKKFREKMYELHVTKAID 1014
+TK Q+ + +++ L ++EL++S K D +K EKM + K +
Sbjct: 351 DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAE 410
Query: 1015 ----KDIREYA 1021
K++++YA
Sbjct: 411 NIRNKEMKKYA 421
Score = 46.4 bits (105), Expect = 6e-04
Identities = 125/634 (19%), Positives = 258/634 (40%), Gaps = 80/634 (12%)
Query: 407 VEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALMELLGNV 466
+E+ EQ++++L ++ + + +LKEKE ++ KEK+ ++ + K + + +V
Sbjct: 11 IEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDV 70
Query: 467 PEKDFAVTINKFECEVRNEVXXXXXXXXXXXXXXXXLEAERKH---IRESLNERRSELTK 523
+ V + E+ V + ER H + + + E+ S + K
Sbjct: 71 -QIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDILEKESIILK 129
Query: 524 AEDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIIN-KYKGQLKDNSCCPLCN 582
E + K D + V++L+ ++ + Q + + + K+ QLK+ N
Sbjct: 130 LERNL-KEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQLKEEE--EETN 186
Query: 583 RGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAK-KDEILSMKSLNEKITTLKD 641
R + + N+ L++ ED K D +K + ++++ ++D
Sbjct: 187 R--QETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRD 244
Query: 642 TE------IPQLEKR----IVDVDTQIKTL--------NETVEEITMSLIEPEQKMTTAK 683
+ I +LEK+ ++D + +T+ N+ VEE + + +
Sbjct: 245 EDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKE 304
Query: 684 QIHGDMPM---------------LDRYIQEIKTVTKKFEAVKEQCGDVDSE--MTLDVAT 726
+I DM M L+ ++E++ + + E KE+C D++++ +
Sbjct: 305 KIIEDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNKEH 364
Query: 727 AKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEE 786
D K++ L++ ++ +++K NA KK L EK +L TQ K + + +E
Sbjct: 365 ENNTDVLGKLTNLQDELQESEQKYNADRKK--WLEEKM------MLITQAKEAENIRNKE 416
Query: 787 SKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEV 846
KK + + L L EK ++ + R RD + A K +
Sbjct: 417 MKKYAED-----RERFFKQQNEMEILTAQLTEK-DSDLQKWREERDQLVAALEIQLKALI 470
Query: 847 AFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
+ N K D EI+Q K+ + E KI+ + K+ ++ T+ + T EI+
Sbjct: 471 SSNVQK--DNEIEQLKR--IISETSKIETQIMDIKPKRISSADPDKLQTEPLST-SFEIS 525
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ 966
+ ++ D ++ L + N++ K EL E + ++ K+ +
Sbjct: 526 RNKIE----DGSVVLDSCEVSTE---------NDQSTRFPKPEL-EIQFTPLQPNKMAVK 571
Query: 967 KAECTGALS-ELKKSLKGFRNELEKSLSKDIEKK 999
CT ++ ++ K+ K NE+E+ L K KK
Sbjct: 572 HPGCTTPVTVKIPKARKRKSNEMEEDLVKCENKK 605
Score = 35.5 bits (78), Expect = 1.2
Identities = 29/129 (22%), Positives = 63/129 (48%), Gaps = 3/129 (2%)
Query: 834 IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQV 893
++A S ++E +++ L AE++ +K +N + ++ + +D L EK+ I ++
Sbjct: 1 VKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEE 60
Query: 894 LTKKIDTLKDEIAKQEVYKR---DLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEEL 950
L +K TL +I KR +L + KA+ + ++ + ++++
Sbjct: 61 LQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKVERSHSAKLEQDI 120
Query: 951 NEKESLIIK 959
EKES+I+K
Sbjct: 121 LEKESIILK 129
>U63610-1|AAB05428.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 51.2 bits (117), Expect = 2e-05
Identities = 80/439 (18%), Positives = 181/439 (41%), Gaps = 25/439 (5%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
E+ +L+R K +E L ++ E++ K + EK+ + + + + + E+
Sbjct: 1652 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1711
Query: 670 MSLIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-----LD 723
EQ++ +Q+ G QE+ + + E ++Q ++ E+
Sbjct: 1712 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1771
Query: 724 VATAKQVDFKQKISTLRNRVKT-TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
AT K+ + + +++ +R ++ K A + T + K + + E ++ ++
Sbjct: 1772 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1831
Query: 783 NL----EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT--EVVRRNRDLIEA 836
L EE+K+Q Q + A+ E KT E+ + ++
Sbjct: 1832 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1891
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD----RQ 892
+A+ E AF + + L+ + QH K ++ + ++++A+D +E+QK ++ D R+
Sbjct: 1892 RLRRLAEDE-AFQR-RRLEEQAAQH-KADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1948
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL----NEKLNGINKE 948
+ ++I LK K K +L+ L ++ + T K+ EL +L +
Sbjct: 1949 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2008
Query: 949 ELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE-KMYEL 1007
E E + K ++ A A E + LK E + + ++ R+ ++ +
Sbjct: 2009 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQE 2068
Query: 1008 HVTKAIDKDIREYAVALDK 1026
K + + + +A A+ +
Sbjct: 2069 AAQKRLQAEEKAHAFAVQQ 2087
Score = 47.6 bits (108), Expect = 3e-04
Identities = 72/433 (16%), Positives = 166/433 (38%), Gaps = 13/433 (3%)
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
A +K + + ++L +K + E+ L ++ + D Q L+E ++ + E ++
Sbjct: 2192 AEMEKHKKFAEQTLRQKAQV--EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2249
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q+ ++ + ++E+ + + EA D + T + KQ
Sbjct: 2250 RS---QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2306
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
Q+ + L +++ A++ L + VQ+ L+ + LQ
Sbjct: 2307 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2366
Query: 799 XXXXXXXXXAITPLEVALKEKIEA--KTEVVRRNRDLIEAGSAYIAKVEVA-FNKVKSLD 855
+ L E+ + +T R R L + A K+ VA ++ ++
Sbjct: 2367 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2426
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT---DRQVLTKKIDTLKDEIAKQEVYK 912
E Q +K EK+ EK + T RQ + L++ IA+ E K
Sbjct: 2427 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREK 2486
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
L L + +++ +Q+ L E + + L+EK+SL+ ++ + Q+KA+
Sbjct: 2487 EKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2545
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ + R E ++ + +E++ + + + + + E + L +
Sbjct: 2546 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 1033 REKMENINMIIRE 1045
+++ + ++ E
Sbjct: 2605 QQRRQQEELLAEE 2617
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 9/174 (5%)
Query: 161 QEDSSWPLDEGKKVKERFDE----IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVK 216
++ + PL + + V+E+ + + + +++ + ++ ++ K Y +K E T K
Sbjct: 1258 EQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYK 1317
Query: 217 AKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
A+ + + KK E + E Y++ L SQ + I + ++ E +
Sbjct: 1318 AQLEPVASPAKK-PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1376
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+AE + E + E E A LEK L H K+QA+ E K+ Q + E
Sbjct: 1377 LAEQQRAEERERLAEVEAA----LEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1426
Score = 41.1 bits (92), Expect = 0.023
Identities = 91/632 (14%), Positives = 243/632 (38%), Gaps = 24/632 (3%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E +QE+ + + E Q+ Q++ +L+ +T + ++++++EE L +++
Sbjct: 1715 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1774
Query: 453 NKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIR 511
K + EL E + + + E E R+ L E +R
Sbjct: 1775 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1834
Query: 512 ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE--KLQDEQNVLQSSMFIINKYK 569
E + + AE+ + + V K E +L+ E + N+
Sbjct: 1835 ALAEEAKRQRQLAEEDAARQ-RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1893
Query: 570 GQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED-LQRASAKKDE 625
+L ++ L + +++++ + + + + ED L++ ++E
Sbjct: 1894 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1953
Query: 626 ILSMKSLNEKITTLK---DTEIPQLEKRIVD-VDTQIKTLNETVEEITMSLIEPEQKMTT 681
IL++K+ EK K + E+ ++ D + ++ + E + ++ E ++
Sbjct: 1954 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 2013
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLR 740
+++ + + ++ K ++ E +K + + +A+Q+ Q+ + R
Sbjct: 2014 EERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKR 2073
Query: 741 NRVKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSDCXX 797
+ + K+ LQ +++ ++L + + EE++ Q + +
Sbjct: 2074 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2133
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
E + + +A+ + ++ + + + A + ++ DAE
Sbjct: 2134 ARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2193
Query: 858 IQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
+++HKK + R+ ++++ L + ++ + +L +++ LK E + + +
Sbjct: 2194 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2253
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
++ L + Q + K + + + + + + + ++ + +Q AE LS
Sbjct: 2254 EEELFSVRVQME--ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2311
Query: 976 ELKKSLKGFRNELEKSLSKD---IEKKFREKM 1004
+ R E+ L++ EK +EKM
Sbjct: 2312 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2343
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKE--LEDSYKKNTSFNKEEEKIA 240
DA++ + + L++ ++ Q KLL+ + ++ Q+E L+++ SF E++ +
Sbjct: 2471 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2530
Query: 241 NEKSSNEIEYNKFILL------ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAE 293
+ E E K L ++Q + +R +Q +E + + ++ E + + EAE
Sbjct: 2531 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2590
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ E+++ L+ + Q+ EE ++
Sbjct: 2591 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2620
>U53204-1|AAB05427.1| 4574|Homo sapiens plectin protein.
Length = 4574
Score = 51.2 bits (117), Expect = 2e-05
Identities = 80/439 (18%), Positives = 181/439 (41%), Gaps = 25/439 (5%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
E+ +L+R K +E L ++ E++ K + EK+ + + + + + E+
Sbjct: 1652 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1711
Query: 670 MSLIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-----LD 723
EQ++ +Q+ G QE+ + + E ++Q ++ E+
Sbjct: 1712 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1771
Query: 724 VATAKQVDFKQKISTLRNRVKT-TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
AT K+ + + +++ +R ++ K A + T + K + + E ++ ++
Sbjct: 1772 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1831
Query: 783 NL----EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT--EVVRRNRDLIEA 836
L EE+K+Q Q + A+ E KT E+ + ++
Sbjct: 1832 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1891
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD----RQ 892
+A+ E AF + + L+ + QH K ++ + ++++A+D +E+QK ++ D R+
Sbjct: 1892 RLRRLAEDE-AFQR-RRLEEQAAQH-KADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1948
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL----NEKLNGINKE 948
+ ++I LK K K +L+ L ++ + T K+ EL +L +
Sbjct: 1949 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEER 2008
Query: 949 ELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE-KMYEL 1007
E E + K ++ A A E + LK E + + ++ R+ ++ +
Sbjct: 2009 RRREAEERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQE 2068
Query: 1008 HVTKAIDKDIREYAVALDK 1026
K + + + +A A+ +
Sbjct: 2069 AAQKRLQAEEKAHAFAVQQ 2087
Score = 47.6 bits (108), Expect = 3e-04
Identities = 72/433 (16%), Positives = 166/433 (38%), Gaps = 13/433 (3%)
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
A +K + + ++L +K + E+ L ++ + D Q L+E ++ + E ++
Sbjct: 2192 AEMEKHKKFAEQTLRQKAQV--EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2249
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q+ ++ + ++E+ + + EA D + T + KQ
Sbjct: 2250 RS---QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2306
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
Q+ + L +++ A++ L + VQ+ L+ + LQ
Sbjct: 2307 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2366
Query: 799 XXXXXXXXXAITPLEVALKEKIEA--KTEVVRRNRDLIEAGSAYIAKVEVA-FNKVKSLD 855
+ L E+ + +T R R L + A K+ VA ++ ++
Sbjct: 2367 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2426
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT---DRQVLTKKIDTLKDEIAKQEVYK 912
E Q +K EK+ EK + T RQ + L++ IA+ E K
Sbjct: 2427 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREK 2486
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
L L + +++ +Q+ L E + + L+EK+SL+ ++ + Q+KA+
Sbjct: 2487 EKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2545
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ + R E ++ + +E++ + + + + + E + L +
Sbjct: 2546 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2604
Query: 1033 REKMENINMIIRE 1045
+++ + ++ E
Sbjct: 2605 QQRRQQEELLAEE 2617
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 9/174 (5%)
Query: 161 QEDSSWPLDEGKKVKERFDE----IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVK 216
++ + PL + + V+E+ + + + +++ + ++ ++ K Y +K E T K
Sbjct: 1258 EQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYK 1317
Query: 217 AKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
A+ + + KK E + E Y++ L SQ + I + ++ E +
Sbjct: 1318 AQLEPVASPAKK-PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1376
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+AE + E + E E A LEK L H K+QA+ E K+ Q + E
Sbjct: 1377 LAEQQRAEERERLAEVEAA----LEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1426
Score = 41.1 bits (92), Expect = 0.023
Identities = 91/632 (14%), Positives = 243/632 (38%), Gaps = 24/632 (3%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E +QE+ + + E Q+ Q++ +L+ +T + ++++++EE L +++
Sbjct: 1715 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1774
Query: 453 NKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIR 511
K + EL E + + + E E R+ L E +R
Sbjct: 1775 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1834
Query: 512 ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE--KLQDEQNVLQSSMFIINKYK 569
E + + AE+ + + V K E +L+ E + N+
Sbjct: 1835 ALAEEAKRQRQLAEEDAARQ-RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1893
Query: 570 GQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED-LQRASAKKDE 625
+L ++ L + +++++ + + + + ED L++ ++E
Sbjct: 1894 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1953
Query: 626 ILSMKSLNEKITTLK---DTEIPQLEKRIVD-VDTQIKTLNETVEEITMSLIEPEQKMTT 681
IL++K+ EK K + E+ ++ D + ++ + E + ++ E ++
Sbjct: 1954 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 2013
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLR 740
+++ + + ++ K ++ E +K + + +A+Q+ Q+ + R
Sbjct: 2014 EERVQKSLAAEEEAARQRKAALEEVERLKANVEEARRLRERAEQESARQLQLAQEAAQKR 2073
Query: 741 NRVKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSDCXX 797
+ + K+ LQ +++ ++L + + EE++ Q + +
Sbjct: 2074 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2133
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
E + + +A+ + ++ + + + A + ++ DAE
Sbjct: 2134 ARRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2193
Query: 858 IQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
+++HKK + R+ ++++ L + ++ + +L +++ LK E + + +
Sbjct: 2194 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2253
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
++ L + Q + K + + + + + + + ++ + +Q AE LS
Sbjct: 2254 EEELFSVRVQME--ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2311
Query: 976 ELKKSLKGFRNELEKSLSKD---IEKKFREKM 1004
+ R E+ L++ EK +EKM
Sbjct: 2312 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2343
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKE--LEDSYKKNTSFNKEEEKIA 240
DA++ + + L++ ++ Q KLL+ + ++ Q+E L+++ SF E++ +
Sbjct: 2471 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2530
Query: 241 NEKSSNEIEYNKFILL------ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAE 293
+ E E K L ++Q + +R +Q +E + + ++ E + + EAE
Sbjct: 2531 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2590
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ E+++ L+ + Q+ EE ++
Sbjct: 2591 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2620
>S78271-1|AAB34405.1| 1233|Homo sapiens SB1.8/DXS423E protein.
Length = 1233
Score = 51.2 bits (117), Expect = 2e-05
Identities = 77/367 (20%), Positives = 151/367 (41%), Gaps = 27/367 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKT 443
K NE+ IE+ +E+ K +E+ ++ MD++ ++ + +K+ K ++E++ IE+ +K
Sbjct: 227 KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE 286
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXX 502
K+ +L N+ + ++ N K + K + +
Sbjct: 287 KDSEL----NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 503 LEAERKHIRESLNERRS----ELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQNV 557
+E R+ E + E +LT E+++ K + + +EK +Q
Sbjct: 343 VEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKA 402
Query: 558 LQSSMFIINKYKGQLKDNSCCPLCNRGFENES--EXXXXXXXXXXXXMNVPGKLE-KVTE 614
Q + + + K + + L EN+ E + KLE ++TE
Sbjct: 403 DQDRLDLEERKKVETEAKIKQKL-REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTE 461
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE----KRIVDVDTQIKTLNE-TVEEIT 669
+++ A + DEI K LN+ + L D I + E +R ++ IK L +V
Sbjct: 462 EVEMAKRRIDEI--NKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRL 519
Query: 670 MSLIEPEQK---MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ L +P QK + K + +M + + KT + +KEQ G+ ++ + LD
Sbjct: 520 IDLCQPTQKKYQIAVTKVLGKNMDAI--IVDSEKTGRDCIQYIKEQRGEPETFLPLDYLE 577
Query: 727 AKQVDFK 733
K D K
Sbjct: 578 VKPTDEK 584
Score = 48.0 bits (109), Expect = 2e-04
Identities = 56/301 (18%), Positives = 127/301 (42%), Gaps = 17/301 (5%)
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN-AHNKKLQ 758
K V K E + ++ +M A+ + + L+ R+K +Q L + L
Sbjct: 669 KAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLA 728
Query: 759 TLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
++K+K + EL N ++ DI + +S+++ D E+ ++
Sbjct: 729 LNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRN 788
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
E + E V+R + IAK + F K+ +K + + +K+
Sbjct: 789 IREFEEEKVKRQNE--------IAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQ 840
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL 938
+ + + +I ++ + + + + +A+ + DL + +K++ + N + + E+
Sbjct: 841 TVKKDENEIEKLKKEEQRHMKIIDETMAQLQ----DLKNQHLAKKSEVNDKNHEME--EI 894
Query: 939 NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+KL G NKE + ++ + +TKL Q++++ L K ++ + L K DI +
Sbjct: 895 RKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACK--MQDIKLPLSKGTMDDISQ 952
Query: 999 K 999
+
Sbjct: 953 E 953
Score = 47.6 bits (108), Expect = 3e-04
Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 21/221 (9%)
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
A++Q K E+E I++ N +L K K+I D+ K++D ++DE+ ++ K++L
Sbjct: 219 AQVQLQLFKLYHNEVE-IEKLNKELASKNKEIEKDK----KRMDKVEDELKEK---KKEL 270
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
+R+ Q +++D ELN+K + + KE+ K KL K A
Sbjct: 271 --GKMMREQQQIEKEIKEKDSELNQK----RPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Query: 976 ELKKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHR 1033
KK KG +ELEK + + ++F E+M E ++ D + E V K
Sbjct: 325 HYKKR-KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQV---KKYHRLKE 380
Query: 1034 EKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERR 1074
E + + +EL K R D + E VE+E +
Sbjct: 381 EASKRAATLAQEL-EKFNRDQKADQDRLDLEERKKVETEAK 420
Score = 41.9 bits (94), Expect = 0.013
Identities = 86/420 (20%), Positives = 175/420 (41%), Gaps = 43/420 (10%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++ K ED Q +K I + + ++ D +L+ +V Q++ E
Sbjct: 174 EMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + + E K+I D +D+ E+K K+ + + ++ E+ +
Sbjct: 233 VEIEKLNKELASKN-KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
Q Q I N KKL A K LQ + K K ++ +K +++++E++
Sbjct: 292 NQKR-PQYIKAKENTSHKI-KKLEAAKKSLQNAQKHYKKRKGDMDELEK---EMLSVEKA 346
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+++ + +T E +K+ K E +R +A +A+
Sbjct: 347 RQEFEERMEEESQSQGRD---LTLEENQVKKYHRLKEEASKR--------AATLAQELEK 395
Query: 848 FNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
FN+ + D + + ++K V E KI++ ++ E QK+I + L + I T K +
Sbjct: 396 FNRDQKADQDRLDLEERKKVETEA-KIKQKLREIEENQKRI----EKLEEYITTSKQSLE 450
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ 966
+Q+ + +L + + + K + D N ELN+ + + ++ +ES +Q Q+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEIN-----KELNQVMEQLGDARIDRQES--SRQ----QR 499
Query: 967 KAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
KAE + +K+ G L + +KK Y++ VTK + K++ V +K
Sbjct: 500 KAE---IMESIKRLYPGSVYGRLIDLCQPTQKK-----YQIAVTKVLGKNMDAIIVDSEK 551
Score = 39.9 bits (89), Expect = 0.054
Identities = 57/247 (23%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 85 KIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHE 144
K + KD +L R + A K + L++ ++ + K R D+D L E
Sbjct: 282 KEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNA--QKHYKKRKGDMDELEKE 339
Query: 145 ELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQN 204
L V KA +E S +G+ + +++ KY + K AQ
Sbjct: 340 MLSVEKARQEFEERMEEESQS----QGRDLTLEENQV---KKYHRLKEEASKRAATLAQE 392
Query: 205 LKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKI 264
L E + KA Q L+ +K + E KI ++ EIE +NQ++I
Sbjct: 393 L---EKFNRDQKADQDRLDLEERKKV---ETEAKI--KQKLREIE---------ENQKRI 435
Query: 265 DKRNEQIVETAKIAEIENITEVQTNEEAENATKTI------LEKVESLKSDHKVQKSQAD 318
+K E I + + E + E + EE E A + I L +V D ++ + ++
Sbjct: 436 EKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESS 495
Query: 319 EEEKKAQ 325
+++KA+
Sbjct: 496 RQQRKAE 502
Score = 37.9 bits (84), Expect = 0.22
Identities = 48/223 (21%), Positives = 107/223 (47%), Gaps = 17/223 (7%)
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
E+ +N++ IE + KVE +++K E+ + ++ E E I+E + +L +K+
Sbjct: 241 ELASKNKE-IEKDKKRMDKVE---DELKEKKKELGKMMREQQQIEKE-IKEKDSELNQKR 295
Query: 885 KQIMTDRQVLT---KKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE 940
Q + ++ + KK++ K + Q+ YK+ D L K + +++ +E E
Sbjct: 296 PQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Query: 941 KLNGINKEELNEKESLIIKQTKLFQQKAECTGALS-ELKKSLKGF-----RNELEKSLSK 994
+ + +L +E+ + K +L ++ ++ L+ EL+K + R +LE+
Sbjct: 356 EESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKV 415
Query: 995 DIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKME 1037
+ E K ++K+ E+ + + + EY + L E ++K+E
Sbjct: 416 ETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEE--QKKLE 456
Score = 33.5 bits (73), Expect = 4.7
Identities = 61/349 (17%), Positives = 135/349 (38%), Gaps = 28/349 (8%)
Query: 402 EDEKAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLKNKHKTALME 461
E++ + ++ +K K +K+ A ++ +++ + + QL + K H +E
Sbjct: 179 EEDTQFNYHRKKNIAAERKEAKQEKEEADRYQR--LKDEVVRAQVQLQLFKLYHNEVEIE 236
Query: 462 LLGN-VPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXXLEAERKHIRESLNERRS 519
L + K+ + +K + V +E+ +E E K LN++R
Sbjct: 237 KLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSELNQKRP 296
Query: 520 ELTKA-EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFIINKYKGQLKDNSCC 578
+ KA E+ +K + +L +K + + + L+ M + K + + ++
Sbjct: 297 QYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEER--- 353
Query: 579 PLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKSLNEKITT 638
E ES+ N K ++ E+ + +A + L + ++K
Sbjct: 354 ------MEEESQSQGRDLTLEE---NQVKKYHRLKEEASKRAATLAQELEKFNRDQKAD- 403
Query: 639 LKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQE 698
+ E++ V+ + +IK +EE + + E+ +TT+KQ + L+ + E
Sbjct: 404 --QDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTE 461
Query: 699 --------IKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTL 739
I + K+ V EQ GD + ++ + + I L
Sbjct: 462 EVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRL 510
>D80000-1|BAA11495.2| 1233|Homo sapiens KIAA0178 protein.
Length = 1233
Score = 51.2 bits (117), Expect = 2e-05
Identities = 77/367 (20%), Positives = 151/367 (41%), Gaps = 27/367 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKT 443
K NE+ IE+ +E+ K +E+ ++ MD++ ++ + +K+ K ++E++ IE+ +K
Sbjct: 227 KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE 286
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXX 502
K+ +L N+ + ++ N K + K + +
Sbjct: 287 KDSEL----NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 503 LEAERKHIRESLNERRS----ELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQNV 557
+E R+ E + E +LT E+++ K + + +EK +Q
Sbjct: 343 VEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKA 402
Query: 558 LQSSMFIINKYKGQLKDNSCCPLCNRGFENES--EXXXXXXXXXXXXMNVPGKLE-KVTE 614
Q + + + K + + L EN+ E + KLE ++TE
Sbjct: 403 DQDRLDLEERKKVETEAKIKQKL-REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTE 461
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE----KRIVDVDTQIKTLNE-TVEEIT 669
+++ A + DEI K LN+ + L D I + E +R ++ IK L +V
Sbjct: 462 EVEMAKRRIDEI--NKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRL 519
Query: 670 MSLIEPEQK---MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ L +P QK + K + +M + + KT + +KEQ G+ ++ + LD
Sbjct: 520 IDLCQPTQKKYQIAVTKVLGKNMDAI--IVDSEKTGRDCIQYIKEQRGEPETFLPLDYLE 577
Query: 727 AKQVDFK 733
K D K
Sbjct: 578 VKPTDEK 584
Score = 48.0 bits (109), Expect = 2e-04
Identities = 56/301 (18%), Positives = 127/301 (42%), Gaps = 17/301 (5%)
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN-AHNKKLQ 758
K V K E + ++ +M A+ + + L+ R+K +Q L + L
Sbjct: 669 KAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLA 728
Query: 759 TLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
++K+K + EL N ++ DI + +S+++ D E+ ++
Sbjct: 729 LNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRN 788
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
E + E V+R + IAK + F K+ +K + + +K+
Sbjct: 789 IREFEEEKVKRQNE--------IAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQ 840
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL 938
+ + + +I ++ + + + + +A+ + DL + +K++ + N + + E+
Sbjct: 841 TVKKDENEIEKLKKEEQRHMKIIDETMAQLQ----DLKNQHLAKKSEVNDKNHEME--EI 894
Query: 939 NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+KL G NKE + ++ + +TKL Q++++ L K ++ + L K DI +
Sbjct: 895 RKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACK--MQDIKLPLSKGTMDDISQ 952
Query: 999 K 999
+
Sbjct: 953 E 953
Score = 47.6 bits (108), Expect = 3e-04
Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 21/221 (9%)
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
A++Q K E+E I++ N +L K K+I D+ K++D ++DE+ ++ K++L
Sbjct: 219 AQVQLQLFKLYHNEVE-IEKLNKELASKNKEIEKDK----KRMDKVEDELKEK---KKEL 270
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
+R+ Q +++D ELN+K + + KE+ K KL K A
Sbjct: 271 --GKMMREQQQIEKEIKEKDSELNQK----RPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Query: 976 ELKKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHR 1033
KK KG +ELEK + + ++F E+M E ++ D + E V K
Sbjct: 325 HYKKR-KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQV---KKYHRLKE 380
Query: 1034 EKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERR 1074
E + + +EL K R D + E VE+E +
Sbjct: 381 EASKRAATLAQEL-EKFNRDQKADQDRLDLEERKKVETEAK 420
Score = 41.9 bits (94), Expect = 0.013
Identities = 86/420 (20%), Positives = 175/420 (41%), Gaps = 43/420 (10%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++ K ED Q +K I + + ++ D +L+ +V Q++ E
Sbjct: 174 EMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + + E K+I D +D+ E+K K+ + + ++ E+ +
Sbjct: 233 VEIEKLNKELASKN-KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
Q Q I N KKL A K LQ + K K ++ +K +++++E++
Sbjct: 292 NQKR-PQYIKAKENTSHKI-KKLEAAKKSLQNAQKHYKKRKGDMDELEK---EMLSVEKA 346
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+++ + +T E +K+ K E +R +A +A+
Sbjct: 347 RQEFEERMEEESQSQGRD---LTLEENQVKKYHRLKEEASKR--------AATLAQELEK 395
Query: 848 FNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
FN+ + D + + ++K V E KI++ ++ E QK+I + L + I T K +
Sbjct: 396 FNRDQKADQDRLDLEERKKVETEA-KIKQKLREIEENQKRI----EKLEEYITTSKQSLE 450
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ 966
+Q+ + +L + + + K + D N ELN+ + + ++ +ES +Q Q+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEIN-----KELNQVMEQLGDARIDRQES--SRQ----QR 499
Query: 967 KAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
KAE + +K+ G L + +KK Y++ VTK + K++ V +K
Sbjct: 500 KAE---IMESIKRLYPGSVYGRLIDLCQPTQKK-----YQIAVTKVLGKNMDAIIVDSEK 551
Score = 39.9 bits (89), Expect = 0.054
Identities = 57/247 (23%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 85 KIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHE 144
K + KD +L R + A K + L++ ++ + K R D+D L E
Sbjct: 282 KEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNA--QKHYKKRKGDMDELEKE 339
Query: 145 ELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQN 204
L V KA +E S +G+ + +++ KY + K AQ
Sbjct: 340 MLSVEKARQEFEERMEEESQS----QGRDLTLEENQV---KKYHRLKEEASKRAATLAQE 392
Query: 205 LKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKI 264
L E + KA Q L+ +K + E KI ++ EIE +NQ++I
Sbjct: 393 L---EKFNRDQKADQDRLDLEERKKV---ETEAKI--KQKLREIE---------ENQKRI 435
Query: 265 DKRNEQIVETAKIAEIENITEVQTNEEAENATKTI------LEKVESLKSDHKVQKSQAD 318
+K E I + + E + E + EE E A + I L +V D ++ + ++
Sbjct: 436 EKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESS 495
Query: 319 EEEKKAQ 325
+++KA+
Sbjct: 496 RQQRKAE 502
Score = 37.9 bits (84), Expect = 0.22
Identities = 48/223 (21%), Positives = 107/223 (47%), Gaps = 17/223 (7%)
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
E+ +N++ IE + KVE +++K E+ + ++ E E I+E + +L +K+
Sbjct: 241 ELASKNKE-IEKDKKRMDKVE---DELKEKKKELGKMMREQQQIEKE-IKEKDSELNQKR 295
Query: 885 KQIMTDRQVLT---KKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE 940
Q + ++ + KK++ K + Q+ YK+ D L K + +++ +E E
Sbjct: 296 PQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Query: 941 KLNGINKEELNEKESLIIKQTKLFQQKAECTGALS-ELKKSLKGF-----RNELEKSLSK 994
+ + +L +E+ + K +L ++ ++ L+ EL+K + R +LE+
Sbjct: 356 EESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKV 415
Query: 995 DIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKME 1037
+ E K ++K+ E+ + + + EY + L E ++K+E
Sbjct: 416 ETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEE--QKKLE 456
Score = 33.9 bits (74), Expect = 3.5
Identities = 65/363 (17%), Positives = 142/363 (39%), Gaps = 33/363 (9%)
Query: 395 ECQQEINEDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEK----EMIEENLKTKEKQ 447
E QE ++ +K + + E++ + I +K+ + KE+ + +++ + + Q
Sbjct: 163 ELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQ 222
Query: 448 LIVLKNKHKTALMELLGN-VPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXXLEA 505
L + K H +E L + K+ + +K + V +E+ +E
Sbjct: 223 LQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEK 282
Query: 506 ERKHIRESLNERRSELTKA-EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFI 564
E K LN++R + KA E+ +K + +L +K + + + L+ M
Sbjct: 283 EIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 565 INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD 624
+ K + + ++ E ES+ N K ++ E+ + +A
Sbjct: 343 VEKARQEFEER---------MEEESQSQGRDLTLEE---NQVKKYHRLKEEASKRAATLA 390
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ 684
+ L + ++K + E++ V+ + +IK +EE + + E+ +TT+KQ
Sbjct: 391 QELEKFNRDQKAD---QDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQ 447
Query: 685 IHGDMPMLDRYIQE--------IKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI 736
+ L+ + E I + K+ V EQ GD + ++ + + I
Sbjct: 448 SLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESI 507
Query: 737 STL 739
L
Sbjct: 508 KRL 510
>D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein.
Length = 709
Score = 51.2 bits (117), Expect = 2e-05
Identities = 94/523 (17%), Positives = 222/523 (42%), Gaps = 68/523 (13%)
Query: 390 ELNIEECQQE---INEDEKAVEQYEQEMDELSQK---ITKLQKQTAKLKEK--------- 434
E+ ++ QQE + D ++ Y E+D L +K + KL+ + ++ KE+
Sbjct: 210 EIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKA 269
Query: 435 ---EMIEENLKTKEKQLIVLKNKHKT-ALMELLGNVPEKDFAVTINKFECEVRNEVXXXX 490
E+ E+N E + ++ T A + L + +++ + + E+ ++
Sbjct: 270 RVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK 329
Query: 491 XXXXXXXXXXXXLEAERKHIRESLN-----ERRSELTKAEDKIYKACGTQPYDVTLSKY- 544
+ A+++ + ESL+ E+ S ++ + K+ G + ++T S+
Sbjct: 330 IEELMEENMTLEM-AQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLL 388
Query: 545 ---------TTTVEKLQDEQNVLQSSMF-IINKYKGQLKDNSCCPLCNRGFENESEXXXX 594
T TVE+L+ + ++ + I+ K + + + E +
Sbjct: 389 KLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQN 448
Query: 595 XXXXXXXXMNVPGKLEKVTEDLQRASAKKDEILSMKS--LNEKITTLKDTEIPQLEKRIV 652
M +LEK E L+ S ++ +IL ++ LN+ +++L+ E R+
Sbjct: 449 CQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVK 508
Query: 653 DVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQ 712
D++ + K L+E+++E + L +I + + + ++ K ++ E ++ +
Sbjct: 509 DIEKENKILHESIKETSSKL----------SKIEFEKRQIKKELEHYKEKGERAEELENE 558
Query: 713 CGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELL 772
++ E L ++KI+ L K T +K+ A ++ L + K K+ L
Sbjct: 559 LHHLEKENEL---------LQKKITNL----KITCEKIEALEQENSELERENRKLKKTLD 605
Query: 773 NTQKKVQDIVNLEESKKQL-QSDCXXXXXXXXXXXXAITPLEVALKEK-IEAKTEVVRRN 830
+ + + +LE+ QL + + ++ ++ L+ K +E++ E +++
Sbjct: 606 SFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKG 665
Query: 831 RDLIEAGSAYIAKVEVAFNKVKSLDAEIQQ-----HKKKNVPR 868
+L++A ++EV++ + + +Q+ +KKK PR
Sbjct: 666 LELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKKKRPR 708
Score = 41.5 bits (93), Expect = 0.018
Identities = 84/480 (17%), Positives = 210/480 (43%), Gaps = 34/480 (7%)
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVD---TQIKTLNETVEEI--T 669
D + A +DE+ +++ ++ L ++E+ + ++R+ D++ +++ L E + + T
Sbjct: 226 DARSARMYRDELDALREKAVRVDKL-ESEVSRYKERLHDIEFYKARVEELKEDNQVLLET 284
Query: 670 MSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGD-----VDSEMTLDV 724
+++E + + T A+ + L++ ++K E ++ ++ MTL++
Sbjct: 285 KTMLEDQLEGTRARS--DKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEM 342
Query: 725 ATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKA---KEELLNTQ--KKVQ 779
A + +D + ++ T + A K L + T + K E+ N K V+
Sbjct: 343 AQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVE 402
Query: 780 DIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSA 839
++ +S + S + LE + ++ ++ ++DL++ A
Sbjct: 403 ELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKE-KA 461
Query: 840 YIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ-KQIMTDRQVLTKKI 898
+ K + +I + + +++ + + +++ + E + K I + ++L + I
Sbjct: 462 QLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESI 521
Query: 899 DTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLII 958
+++K E KR + L K + + + + EK N + ++++ +
Sbjct: 522 KETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCE 581
Query: 959 KQTKLFQQKAECTGALSELKKSLKGFRN---ELEKSLSKDIEKKFREKMYEL--HVTKAI 1013
K L Q+ +E +LKK+L F+N +LE SL K+ + E+ EL +V
Sbjct: 582 KIEALEQENSELERENRKLKKTLDSFKNLTFQLE-SLEKE-NSQLDEENLELRRNVESLK 639
Query: 1014 DKDIREYAVALDKCLMEFHREKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESER 1073
++ + L+ +E +E+++ +++ ++K R +E+ +G L +E++R
Sbjct: 640 CASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTER------LEVSYQG-LDIENQR 692
>BX537985-1|CAD97945.1| 1202|Homo sapiens hypothetical protein
protein.
Length = 1202
Score = 51.2 bits (117), Expect = 2e-05
Identities = 84/410 (20%), Positives = 176/410 (42%), Gaps = 28/410 (6%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRI---VDVDTQIKTLN-E 663
+LEK + L++ + KD L N KI L + E L K I + ++K L E
Sbjct: 8 QLEKENKRLRQQAEIKDTTLEEN--NVKIGNL-EKENKTLSKEIGIYKESCVRLKELEKE 64
Query: 664 TVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAV---KEQCGDVDSEM 720
E + + I+ + +T + + + + +++ +T + E + KE+ + E
Sbjct: 65 NKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERL--LHDEQ 122
Query: 721 TLDVATAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQD 780
+ D + K ++ K + STL+ ++ ++K+ A +L+ + ++EL +K +
Sbjct: 123 STDDSRYKLLESKLE-STLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEA 181
Query: 781 IVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAY 840
+ ++ ++ +QS + LK K + EV R N L A
Sbjct: 182 LKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVK-DRLIEVERNNATLQAEKQAL 240
Query: 841 IAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDT 900
+++ + +L +I +++ V +QE N L + ++ + L + +
Sbjct: 241 KTQLKQLETQNNNLQTQILALQRQTV-----SLQEQNTTLQTQNAKLQVENSTLNSQSTS 295
Query: 901 LKDEIAKQEVYKRDLD-DNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIK 959
L ++ A+ + + L+ +N + K + D+ + + +EKL +++ + +E ESLI K
Sbjct: 296 LMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISK 355
Query: 960 -------QTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFRE 1002
L + + ++L K KG +LEK L + EK E
Sbjct: 356 HGTLKSAHKNLEVEHRDLEDRYNQLLKQ-KGQLEDLEKMLKVEQEKMLLE 404
Score = 37.5 bits (83), Expect = 0.29
Identities = 30/139 (21%), Positives = 64/139 (46%), Gaps = 5/139 (3%)
Query: 187 YSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSN 246
Y + RLK++ K+ + +K T+ +++L K N + EK+ +E
Sbjct: 51 YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 110
Query: 247 EIEYNKFILLESQNQEKIDKRNEQIVETA--KIAEI--ENITEVQTN-EEAENATKTILE 301
+ + + E + K E +E+ K EI E I ++ EE+ N + + +
Sbjct: 111 GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQ 170
Query: 302 KVESLKSDHKVQKSQADEE 320
+++++K +++ K + DEE
Sbjct: 171 ELKTVKKNYEALKQRQDEE 189
>BC112127-1|AAI12128.1| 1233|Homo sapiens SMC1 structural
maintenance of chromosomes 1-like 1 protein.
Length = 1233
Score = 51.2 bits (117), Expect = 2e-05
Identities = 77/367 (20%), Positives = 151/367 (41%), Gaps = 27/367 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKT 443
K NE+ IE+ +E+ K +E+ ++ MD++ ++ + +K+ K ++E++ IE+ +K
Sbjct: 227 KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE 286
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXX 502
K+ +L N+ + ++ N K + K + +
Sbjct: 287 KDSEL----NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 503 LEAERKHIRESLNERRS----ELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQNV 557
+E R+ E + E +LT E+++ K + + +EK +Q
Sbjct: 343 VEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKA 402
Query: 558 LQSSMFIINKYKGQLKDNSCCPLCNRGFENES--EXXXXXXXXXXXXMNVPGKLE-KVTE 614
Q + + + K + + L EN+ E + KLE ++TE
Sbjct: 403 DQDRLDLEERKKVETEAKIKQKL-REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTE 461
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE----KRIVDVDTQIKTLNE-TVEEIT 669
+++ A + DEI K LN+ + L D I + E +R ++ IK L +V
Sbjct: 462 EVEMAKRRIDEI--NKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRL 519
Query: 670 MSLIEPEQK---MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ L +P QK + K + +M + + KT + +KEQ G+ ++ + LD
Sbjct: 520 IDLCQPTQKKYQIAVTKVLGKNMDAI--IVDSEKTGRDCIQYIKEQRGEPETFLPLDYLE 577
Query: 727 AKQVDFK 733
K D K
Sbjct: 578 VKPTDEK 584
Score = 48.0 bits (109), Expect = 2e-04
Identities = 56/301 (18%), Positives = 127/301 (42%), Gaps = 17/301 (5%)
Query: 700 KTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKISTLRNRVKTTQKKLN-AHNKKLQ 758
K V K E + ++ +M A+ + + L+ R+K +Q L + L
Sbjct: 669 KAVDKLKEKKERLTEELKEQMKAKRKEAELRQVQSQAHGLQMRLKYSQSDLEQTKTRHLA 728
Query: 759 TLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKE 818
++K+K + EL N ++ DI + +S+++ D E+ ++
Sbjct: 729 LNLQEKSKLESELANFGPRINDIKRIIQSREREMKDLKEKMNQVEDEVFEEFCREIGVRN 788
Query: 819 KIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEAND 878
E + E V+R + IAK + F K+ +K + + +K+
Sbjct: 789 IREFEEEKVKRQNE--------IAKKRLEFENQKTRLGIQLDFEKNQLKEDQDKVHMWEQ 840
Query: 879 KLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDEL 938
+ + + +I ++ + + + + +A+ + DL + +K++ + N + + E+
Sbjct: 841 TVKKDENEIEKLKKEEQRHMKIIDETMAQLQ----DLKNQHLAKKSEVNDKNHEME--EI 894
Query: 939 NEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEK 998
+KL G NKE + ++ + +TKL Q++++ L K ++ + L K DI +
Sbjct: 895 RKKLGGANKEMTHLQKEVTAIETKLEQKRSDRHNLLQACK--MQDIKLPLSKGTMDDISQ 952
Query: 999 K 999
+
Sbjct: 953 E 953
Score = 47.6 bits (108), Expect = 3e-04
Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 21/221 (9%)
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
A++Q K E+E I++ N +L K K+I D+ K++D ++DE+ ++ K++L
Sbjct: 219 AQVQLQLFKLYHNEVE-IEKLNKELASKNKEIEKDK----KRMDKVEDELKEK---KKEL 270
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
+R+ Q +++D ELN+K + + KE+ K KL K A
Sbjct: 271 --GKMMREQQQIEKEIKEKDSELNQK----RPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Query: 976 ELKKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHR 1033
KK KG +ELEK + + ++F E+M E ++ D + E V K
Sbjct: 325 HYKKR-KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQV---KKYHRLKE 380
Query: 1034 EKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERR 1074
E + + +EL K R D + E VE+E +
Sbjct: 381 EASKRAATLAQEL-EKFNRDQKADQDRLDLEERKKVETEAK 420
Score = 41.9 bits (94), Expect = 0.013
Identities = 86/420 (20%), Positives = 175/420 (41%), Gaps = 43/420 (10%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++ K ED Q +K I + + ++ D +L+ +V Q++ E
Sbjct: 174 EMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + + E K+I D +D+ E+K K+ + + ++ E+ +
Sbjct: 233 VEIEKLNKELASKN-KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
Q Q I N KKL A K LQ + K K ++ +K +++++E++
Sbjct: 292 NQKR-PQYIKAKENTSHKI-KKLEAAKKSLQNAQKHYKKRKGDMDELEK---EMLSVEKA 346
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+++ + +T E +K+ K E +R +A +A+
Sbjct: 347 RQEFEERMEEESQSQGRD---LTLEENQVKKYHRLKEEASKR--------AATLAQELEK 395
Query: 848 FNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
FN+ + D + + ++K V E KI++ ++ E QK+I + L + I T K +
Sbjct: 396 FNRDQKADQDRLDLEERKKVETEA-KIKQKLREIEENQKRI----EKLEEYITTSKQSLE 450
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ 966
+Q+ + +L + + + K + D N ELN+ + + ++ +ES +Q Q+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEIN-----KELNQVMEQLGDARIDRQES--SRQ----QR 499
Query: 967 KAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
KAE + +K+ G L + +KK Y++ VTK + K++ V +K
Sbjct: 500 KAE---IMESIKRLYPGSVYGRLIDLCQPTQKK-----YQIAVTKVLGKNMDAIIVDSEK 551
Score = 39.9 bits (89), Expect = 0.054
Identities = 57/247 (23%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 85 KIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHE 144
K + KD +L R + A K + L++ ++ + K R D+D L E
Sbjct: 282 KEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNA--QKHYKKRKGDMDELEKE 339
Query: 145 ELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQN 204
L V KA +E S +G+ + +++ KY + K AQ
Sbjct: 340 MLSVEKARQEFEERMEEESQS----QGRDLTLEENQV---KKYHRLKEEASKRAATLAQE 392
Query: 205 LKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKI 264
L E + KA Q L+ +K + E KI ++ EIE +NQ++I
Sbjct: 393 L---EKFNRDQKADQDRLDLEERKKV---ETEAKI--KQKLREIE---------ENQKRI 435
Query: 265 DKRNEQIVETAKIAEIENITEVQTNEEAENATKTI------LEKVESLKSDHKVQKSQAD 318
+K E I + + E + E + EE E A + I L +V D ++ + ++
Sbjct: 436 EKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESS 495
Query: 319 EEEKKAQ 325
+++KA+
Sbjct: 496 RQQRKAE 502
Score = 37.9 bits (84), Expect = 0.22
Identities = 48/223 (21%), Positives = 107/223 (47%), Gaps = 17/223 (7%)
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
E+ +N++ IE + KVE +++K E+ + ++ E E I+E + +L +K+
Sbjct: 241 ELASKNKE-IEKDKKRMDKVE---DELKEKKKELGKMMREQQQIEKE-IKEKDSELNQKR 295
Query: 885 KQIMTDRQVLT---KKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE 940
Q + ++ + KK++ K + Q+ YK+ D L K + +++ +E E
Sbjct: 296 PQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Query: 941 KLNGINKEELNEKESLIIKQTKLFQQKAECTGALS-ELKKSLKGF-----RNELEKSLSK 994
+ + +L +E+ + K +L ++ ++ L+ EL+K + R +LE+
Sbjct: 356 EESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKV 415
Query: 995 DIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKME 1037
+ E K ++K+ E+ + + + EY + L E ++K+E
Sbjct: 416 ETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEE--QKKLE 456
Score = 33.9 bits (74), Expect = 3.5
Identities = 65/363 (17%), Positives = 142/363 (39%), Gaps = 33/363 (9%)
Query: 395 ECQQEINEDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEK----EMIEENLKTKEKQ 447
E QE ++ +K + + E++ + I +K+ + KE+ + +++ + + Q
Sbjct: 163 ELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQ 222
Query: 448 LIVLKNKHKTALMELLGN-VPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXXLEA 505
L + K H +E L + K+ + +K + V +E+ +E
Sbjct: 223 LQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEK 282
Query: 506 ERKHIRESLNERRSELTKA-EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFI 564
E K LN++R + KA E+ +K + +L +K + + + L+ M
Sbjct: 283 EIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 565 INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD 624
+ K + + ++ E ES+ N K ++ E+ + +A
Sbjct: 343 VEKARQEFEER---------MEEESQSQGRDLTLEE---NQVKKYHRLKEEASKRAATLA 390
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ 684
+ L + ++K + E++ V+ + +IK +EE + + E+ +TT+KQ
Sbjct: 391 QELEKFNRDQKAD---QDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQ 447
Query: 685 IHGDMPMLDRYIQE--------IKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI 736
+ L+ + E I + K+ V EQ GD + ++ + + I
Sbjct: 448 SLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESI 507
Query: 737 STL 739
L
Sbjct: 508 KRL 510
>BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 51.2 bits (117), Expect = 2e-05
Identities = 71/329 (21%), Positives = 143/329 (43%), Gaps = 33/329 (10%)
Query: 712 QCGDVDSEMTLDVA-TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
+C ++++E+ ++ A A + Q T + + +K++ K + + Y+K+ KAKE
Sbjct: 63 KCRELNAEIVVNSAKVATALKLSQDDQTT---IASLKKEIEKAWKMVDSAYDKEQKAKET 119
Query: 771 LLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
+L ++++ ++ L E L D +T KE+ + +EVV+
Sbjct: 120 ILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVT------KERDQLLSEVVKLR 173
Query: 831 RDL---IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQI 887
L E E A + + EIQQ ++ RE K +KL ++ KQI
Sbjct: 174 ESLAQTTEQQQETERSKEEAEHAISQFQQEIQQ-RQNEASREFRK----KEKLEKELKQI 228
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE-KLNGIN 946
D +I L+ + K + + L+ L +K I N ++ EL + ++
Sbjct: 229 QADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQK----ILN-ERAAKELEQFQMRNAK 283
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMY- 1005
++ NE+ SL+ +Q L Q+ + L ++ + R ++ K K RE+++
Sbjct: 284 LQQENEQHSLVCEQ--LSQENQQKALELKAKEEEVHQMRLDIGKL------NKIREQIHK 335
Query: 1006 ELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
+LH T+ ++ ++ L ++ RE
Sbjct: 336 KLHHTEDQKAEVEQHKETLKNQIVGLERE 364
Score = 40.7 bits (91), Expect = 0.031
Identities = 83/407 (20%), Positives = 181/407 (44%), Gaps = 36/407 (8%)
Query: 641 DTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIK 700
+ E+ Q++ + T+IK L + V++ L + EQ++ K ++ + +++ +
Sbjct: 222 EKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILN---ERAAKELEQFQ 278
Query: 701 TVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK---ISTLRNRVKTTQKKLNAHNKKL 757
K + EQ V +++ + K ++ K K + +R + K +KKL
Sbjct: 279 MRNAKLQQENEQHSLVCEQLSQE-NQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKL 337
Query: 758 QTLYEKKTKAKEELLNTQKKVQDIV-NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVAL 816
++K + ++ + ++ + +E SKKQ + D + ++
Sbjct: 338 HHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELD-------RKAMDELLRERDILN 390
Query: 817 KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK-IQE 875
K ++A ++ DL++ +E K +A+ Q+ ++ +E ++ I +
Sbjct: 391 KNMLKA-VNATQKQTDLVKLHEQAKRNLEGEIQNYKD-EAQKQRKIIFHLEKERDRYINQ 448
Query: 876 ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV---YKRDL------DDNLC---LRK 923
A+D L +K M D +V +I + +IA+ E+ +++L D NL L +
Sbjct: 449 ASD-LTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVE 507
Query: 924 AQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKG 983
AQ +IT+ +++ + +++ + KE+++ KES ++K L QQ+ E LK L+
Sbjct: 508 AQDEITDMKRKLKIMIHQVDEL-KEDISAKESALVK-LHLEQQRIE--KEKETLKAELQK 563
Query: 984 FRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLME 1030
R + ++ IEK+ E+ L + D + LD+ + E
Sbjct: 564 LRQQALET-KHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISE 609
Score = 36.3 bits (80), Expect = 0.66
Identities = 41/268 (15%), Positives = 113/268 (42%), Gaps = 18/268 (6%)
Query: 195 KKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKE--EEKIANEKSSNEIEYNK 252
+K+ K+ Q +++ T +KA Q+ ++ S ++ ++ E+KI NE+++ E+E +
Sbjct: 219 EKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELE--Q 276
Query: 253 FILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKV 312
F + ++ Q++ ++++ + E + E++ EE + + + K+ ++
Sbjct: 277 FQMRNAKLQQE-NEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHK 335
Query: 313 QKSQADEEEKKAQGFVDECRS---GHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXX 369
+ ++++ + + + ++ G + + N++
Sbjct: 336 KLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLK 395
Query: 370 XXXXXXXXXXXXXXHKQAENEL--NIEECQQEINEDEKAVEQYEQEMD-------ELSQK 420
H+QA+ L I+ + E + K + E+E D +L+QK
Sbjct: 396 AVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQK 455
Query: 421 ITKLQKQTAKLKEKEMIEENLKTKEKQL 448
+ + + K++E ++ + K E ++
Sbjct: 456 VL-MNMEDIKVRETQIFDYRKKIAESEI 482
Score = 33.1 bits (72), Expect = 6.2
Identities = 21/66 (31%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Query: 394 EECQQEINEDE-KAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
EE + +N + +E + EL QKI LQK+ K +E++E+ L +EK+ + ++
Sbjct: 702 EELENPLNVHRWRKLEASDPNAYELIQKIHTLQKRLIS-KTEEVVEKELLLQEKEKLYME 760
Query: 453 NKHKTA 458
KH A
Sbjct: 761 LKHVLA 766
>BC064368-1|AAH64368.1| 847|Homo sapiens SMC1A protein protein.
Length = 847
Score = 51.2 bits (117), Expect = 2e-05
Identities = 77/367 (20%), Positives = 151/367 (41%), Gaps = 27/367 (7%)
Query: 385 KQAENELNIEECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKT 443
K NE+ IE+ +E+ K +E+ ++ MD++ ++ + +K+ K ++E++ IE+ +K
Sbjct: 227 KLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKE 286
Query: 444 KEKQLIVLKNKHKTALMELLGNVPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXX 502
K+ +L N+ + ++ N K + K + +
Sbjct: 287 KDSEL----NQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 503 LEAERKHIRESLNERRS----ELTKAEDKIYKACG-TQPYDVTLSKYTTTVEKLQDEQNV 557
+E R+ E + E +LT E+++ K + + +EK +Q
Sbjct: 343 VEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKA 402
Query: 558 LQSSMFIINKYKGQLKDNSCCPLCNRGFENES--EXXXXXXXXXXXXMNVPGKLE-KVTE 614
Q + + + K + + L EN+ E + KLE ++TE
Sbjct: 403 DQDRLDLEERKKVETEAKIKQKL-REIEENQKRIEKLEEYITTSKQSLEEQKKLEGELTE 461
Query: 615 DLQRASAKKDEILSMKSLNEKITTLKDTEIPQLE----KRIVDVDTQIKTLNE-TVEEIT 669
+++ A + DEI K LN+ + L D I + E +R ++ IK L +V
Sbjct: 462 EVEMAKRRIDEI--NKELNQVMEQLGDARIDRQESSRQQRKAEIMESIKRLYPGSVYGRL 519
Query: 670 MSLIEPEQK---MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVAT 726
+ L +P QK + K + +M + + KT + +KEQ G+ ++ + LD
Sbjct: 520 IDLCQPTQKKYQIAVTKVLGKNMDAI--IVDSEKTGRDCIQYIKEQRGEPETFLPLDYLE 577
Query: 727 AKQVDFK 733
K D K
Sbjct: 578 VKPTDEK 584
Score = 47.6 bits (108), Expect = 3e-04
Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 21/221 (9%)
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
A++Q K E+E I++ N +L K K+I D+ K++D ++DE+ ++ K++L
Sbjct: 219 AQVQLQLFKLYHNEVE-IEKLNKELASKNKEIEKDK----KRMDKVEDELKEK---KKEL 270
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
+R+ Q +++D ELN+K + + KE+ K KL K A
Sbjct: 271 --GKMMREQQQIEKEIKEKDSELNQK----RPQYIKAKENTSHKIKKLEAAKKSLQNAQK 324
Query: 976 ELKKSLKGFRNELEKSL--SKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHR 1033
KK KG +ELEK + + ++F E+M E ++ D + E V K
Sbjct: 325 HYKKR-KGDMDELEKEMLSVEKARQEFEERMEEESQSQGRDLTLEENQV---KKYHRLKE 380
Query: 1034 EKMENINMIIRELWRKIYRGNDIDYIEIKTEGNLTVESERR 1074
E + + +EL K R D + E VE+E +
Sbjct: 381 EASKRAATLAQEL-EKFNRDQKADQDRLDLEERKKVETEAK 420
Score = 41.9 bits (94), Expect = 0.013
Identities = 86/420 (20%), Positives = 175/420 (41%), Gaps = 43/420 (10%)
Query: 608 KLEKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEE 667
++ K ED Q +K I + + ++ D +L+ +V Q++ E
Sbjct: 174 EMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEAD-RYQRLKDEVVRAQVQLQLFKLYHNE 232
Query: 668 ITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATA 727
+ + + E K+I D +D+ E+K K+ + + ++ E+ +
Sbjct: 233 VEIEKLNKELASKN-KEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEKEIKEKDSEL 291
Query: 728 KQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEES 787
Q Q I N KKL A K LQ + K K ++ +K +++++E++
Sbjct: 292 NQKR-PQYIKAKENTSHKI-KKLEAAKKSLQNAQKHYKKRKGDMDELEK---EMLSVEKA 346
Query: 788 KKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVA 847
+++ + +T E +K+ K E +R +A +A+
Sbjct: 347 RQEFEERMEEESQSQGRD---LTLEENQVKKYHRLKEEASKR--------AATLAQELEK 395
Query: 848 FNKVKSLDAE-IQQHKKKNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIA 906
FN+ + D + + ++K V E KI++ ++ E QK+I + L + I T K +
Sbjct: 396 FNRDQKADQDRLDLEERKKVETEA-KIKQKLREIEENQKRI----EKLEEYITTSKQSLE 450
Query: 907 KQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQ 966
+Q+ + +L + + + K + D N ELN+ + + ++ +ES +Q Q+
Sbjct: 451 EQKKLEGELTEEVEMAKRRIDEIN-----KELNQVMEQLGDARIDRQES--SRQ----QR 499
Query: 967 KAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDK 1026
KAE + +K+ G L + +KK Y++ VTK + K++ V +K
Sbjct: 500 KAE---IMESIKRLYPGSVYGRLIDLCQPTQKK-----YQIAVTKVLGKNMDAIIVDSEK 551
Score = 39.9 bits (89), Expect = 0.054
Identities = 57/247 (23%), Positives = 100/247 (40%), Gaps = 32/247 (12%)
Query: 85 KIVNAKDKQLEVTRSMKVTALAKKKTKFQTLDSFLSTVDESGKTKDVSSRCADLDILMHE 144
K + KD +L R + A K + L++ ++ + K R D+D L E
Sbjct: 282 KEIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNA--QKHYKKRKGDMDELEKE 339
Query: 145 ELGVSKAILNSVVFCHQEDSSWPLDEGKKVKERFDEIFDADKYSDCLDRLKKIRKDYAQN 204
L V KA +E S +G+ + +++ KY + K AQ
Sbjct: 340 MLSVEKARQEFEERMEEESQS----QGRDLTLEENQV---KKYHRLKEEASKRAATLAQE 392
Query: 205 LKLLENYATTVKAKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKI 264
L E + KA Q L+ +K + E KI ++ EIE +NQ++I
Sbjct: 393 L---EKFNRDQKADQDRLDLEERKKV---ETEAKI--KQKLREIE---------ENQKRI 435
Query: 265 DKRNEQIVETAKIAEIENITEVQTNEEAENATKTI------LEKVESLKSDHKVQKSQAD 318
+K E I + + E + E + EE E A + I L +V D ++ + ++
Sbjct: 436 EKLEEYITTSKQSLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESS 495
Query: 319 EEEKKAQ 325
+++KA+
Sbjct: 496 RQQRKAE 502
Score = 37.9 bits (84), Expect = 0.22
Identities = 48/223 (21%), Positives = 107/223 (47%), Gaps = 17/223 (7%)
Query: 825 EVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQ 884
E+ +N++ IE + KVE +++K E+ + ++ E E I+E + +L +K+
Sbjct: 241 ELASKNKE-IEKDKKRMDKVE---DELKEKKKELGKMMREQQQIEKE-IKEKDSELNQKR 295
Query: 885 KQIMTDRQVLT---KKIDTLKDEIAK-QEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE 940
Q + ++ + KK++ K + Q+ YK+ D L K + +++ +E E
Sbjct: 296 PQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLSVEKARQEFEERME 355
Query: 941 KLNGINKEELNEKESLIIKQTKLFQQKAECTGALS-ELKKSLKGF-----RNELEKSLSK 994
+ + +L +E+ + K +L ++ ++ L+ EL+K + R +LE+
Sbjct: 356 EESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKV 415
Query: 995 DIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFHREKME 1037
+ E K ++K+ E+ + + + EY + L E ++K+E
Sbjct: 416 ETEAKIKQKLREIEENQKRIEKLEEYITTSKQSLEE--QKKLE 456
Score = 33.9 bits (74), Expect = 3.5
Identities = 65/363 (17%), Positives = 142/363 (39%), Gaps = 33/363 (9%)
Query: 395 ECQQEINEDEKAVEQYEQEMD---ELSQKITKLQKQTAKLKEK----EMIEENLKTKEKQ 447
E QE ++ +K + + E++ + I +K+ + KE+ + +++ + + Q
Sbjct: 163 ELAQEYDKRKKEMVKAEEDTQFNYHRKKNIAAERKEAKQEKEEADRYQRLKDEVVRAQVQ 222
Query: 448 LIVLKNKHKTALMELLGN-VPEKDFAVTINKFECE-VRNEVXXXXXXXXXXXXXXXXLEA 505
L + K H +E L + K+ + +K + V +E+ +E
Sbjct: 223 LQLFKLYHNEVEIEKLNKELASKNKEIEKDKKRMDKVEDELKEKKKELGKMMREQQQIEK 282
Query: 506 ERKHIRESLNERRSELTKA-EDKIYKACGTQPYDVTLSKYTTTVEKLQDEQNVLQSSMFI 564
E K LN++R + KA E+ +K + +L +K + + + L+ M
Sbjct: 283 EIKEKDSELNQKRPQYIKAKENTSHKIKKLEAAKKSLQNAQKHYKKRKGDMDELEKEMLS 342
Query: 565 INKYKGQLKDNSCCPLCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTEDLQRASAKKD 624
+ K + + ++ E ES+ N K ++ E+ + +A
Sbjct: 343 VEKARQEFEER---------MEEESQSQGRDLTLEE---NQVKKYHRLKEEASKRAATLA 390
Query: 625 EILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQ 684
+ L + ++K + E++ V+ + +IK +EE + + E+ +TT+KQ
Sbjct: 391 QELEKFNRDQKAD---QDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQ 447
Query: 685 IHGDMPMLDRYIQE--------IKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKI 736
+ L+ + E I + K+ V EQ GD + ++ + + I
Sbjct: 448 SLEEQKKLEGELTEEVEMAKRRIDEINKELNQVMEQLGDARIDRQESSRQQRKAEIMESI 507
Query: 737 STL 739
L
Sbjct: 508 KRL 510
>BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open reading
frame 80 protein.
Length = 872
Score = 51.2 bits (117), Expect = 2e-05
Identities = 71/329 (21%), Positives = 143/329 (43%), Gaps = 33/329 (10%)
Query: 712 QCGDVDSEMTLDVA-TAKQVDFKQKISTLRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEE 770
+C ++++E+ ++ A A + Q T + + +K++ K + + Y+K+ KAKE
Sbjct: 63 KCRELNAEIVVNSAKVATALKLSQDDQTT---IASLKKEIEKAWKMVDSAYDKEQKAKET 119
Query: 771 LLNTQKKVQDIVNLEESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKTEVVRRN 830
+L ++++ ++ L E L D +T KE+ + +EVV+
Sbjct: 120 ILALKEEIVNLTKLVEQGSGLSMDQHSNIRDLLRFKEEVT------KERDQLLSEVVKLR 173
Query: 831 RDL---IEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQI 887
L E E A + + EIQQ ++ RE K +KL ++ KQI
Sbjct: 174 ESLAQTTEQQQETERSKEEAEHAISQFQQEIQQ-RQNEASREFRK----KEKLEKELKQI 228
Query: 888 MTDRQVLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNE-KLNGIN 946
D +I L+ + K + + L+ L +K I N ++ EL + ++
Sbjct: 229 QADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQK----ILN-ERAAKELEQFQMRNAK 283
Query: 947 KEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIEKKFREKMY- 1005
++ NE+ SL+ +Q L Q+ + L ++ + R ++ K K RE+++
Sbjct: 284 LQQENEQHSLVCEQ--LSQENQQKALELKAKEEEVHQMRLDIGKL------NKIREQIHK 335
Query: 1006 ELHVTKAIDKDIREYAVALDKCLMEFHRE 1034
+LH T+ ++ ++ L ++ RE
Sbjct: 336 KLHHTEDQKAEVEQHKETLKNQIVGLERE 364
Score = 40.7 bits (91), Expect = 0.031
Identities = 83/407 (20%), Positives = 181/407 (44%), Gaps = 36/407 (8%)
Query: 641 DTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQKMTTAKQIHGDMPMLDRYIQEIK 700
+ E+ Q++ + T+IK L + V++ L + EQ++ K ++ + +++ +
Sbjct: 222 EKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILN---ERAAKELEQFQ 278
Query: 701 TVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQK---ISTLRNRVKTTQKKLNAHNKKL 757
K + EQ V +++ + K ++ K K + +R + K +KKL
Sbjct: 279 MRNAKLQQENEQHSLVCEQLSQE-NQQKALELKAKEEEVHQMRLDIGKLNKIREQIHKKL 337
Query: 758 QTLYEKKTKAKEELLNTQKKVQDIV-NLEESKKQLQSDCXXXXXXXXXXXXAITPLEVAL 816
++K + ++ + ++ + +E SKKQ + D + ++
Sbjct: 338 HHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELD-------RKAMDELLRERDILN 390
Query: 817 KEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEK-IQE 875
K ++A ++ DL++ +E K +A+ Q+ ++ +E ++ I +
Sbjct: 391 KNMLKA-VNATQKQTDLVKLHEQAKRNLEGEIQNYKD-EAQKQRKIIFHLEKERDRYINQ 448
Query: 876 ANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEV---YKRDL------DDNLC---LRK 923
A+D L +K M D +V +I + +IA+ E+ +++L D NL L +
Sbjct: 449 ASD-LTQKVLMNMEDIKVRETQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVE 507
Query: 924 AQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALSELKKSLKG 983
AQ +IT+ +++ + +++ + KE+++ KES ++K L QQ+ E LK L+
Sbjct: 508 AQDEITDMKRKLKIMIHQVDEL-KEDISAKESALVK-LHLEQQRIE--KEKETLKAELQK 563
Query: 984 FRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLME 1030
R + ++ IEK+ E+ L + D + LD+ + E
Sbjct: 564 LRQQALET-KHFIEKQEAEERKLLRIIAEADGERLRQKKELDQVISE 609
Score = 36.3 bits (80), Expect = 0.66
Identities = 41/268 (15%), Positives = 113/268 (42%), Gaps = 18/268 (6%)
Query: 195 KKIRKDYAQNLKLLENYATTVKAKQKELEDSYKKNTSFNKE--EEKIANEKSSNEIEYNK 252
+K+ K+ Q +++ T +KA Q+ ++ S ++ ++ E+KI NE+++ E+E +
Sbjct: 219 EKLEKELKQIQADMDSRQTEIKALQQYVQKSKEELQKLEQQLKEQKILNERAAKELE--Q 276
Query: 253 FILLESQNQEKIDKRNEQIVETAKIAEIENITEVQTNEEAENATKTILEKVESLKSDHKV 312
F + ++ Q++ ++++ + E + E++ EE + + + K+ ++
Sbjct: 277 FQMRNAKLQQE-NEQHSLVCEQLSQENQQKALELKAKEEEVHQMRLDIGKLNKIREQIHK 335
Query: 313 QKSQADEEEKKAQGFVDECRS---GHTQXXXXXXXXXXXXXXXXXXXXXDITSANQSXXX 369
+ ++++ + + + ++ G + + N++
Sbjct: 336 KLHHTEDQKAEVEQHKETLKNQIVGLEREVEASKKQAELDRKAMDELLRERDILNKNMLK 395
Query: 370 XXXXXXXXXXXXXXHKQAENEL--NIEECQQEINEDEKAVEQYEQEMD-------ELSQK 420
H+QA+ L I+ + E + K + E+E D +L+QK
Sbjct: 396 AVNATQKQTDLVKLHEQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQK 455
Query: 421 ITKLQKQTAKLKEKEMIEENLKTKEKQL 448
+ + + K++E ++ + K E ++
Sbjct: 456 VL-MNMEDIKVRETQIFDYRKKIAESEI 482
Score = 33.1 bits (72), Expect = 6.2
Identities = 21/66 (31%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Query: 394 EECQQEINEDE-KAVEQYEQEMDELSQKITKLQKQTAKLKEKEMIEENLKTKEKQLIVLK 452
EE + +N + +E + EL QKI LQK+ K +E++E+ L +EK+ + ++
Sbjct: 702 EELENPLNVHRWRKLEASDPNAYELIQKIHTLQKRLIS-KTEEVVEKELLLQEKEKLYME 760
Query: 453 NKHKTA 458
KH A
Sbjct: 761 LKHVLA 766
>AY480051-1|AAR95684.1| 4547|Homo sapiens plectin 11 protein.
Length = 4547
Score = 51.2 bits (117), Expect = 2e-05
Identities = 79/412 (19%), Positives = 174/412 (42%), Gaps = 27/412 (6%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
E+ +L+R K +E L ++ E++ K + EK+ + + + + + E+
Sbjct: 1625 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1684
Query: 670 MSLIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-----LD 723
EQ++ +Q+ G QE+ + + E ++Q ++ E+
Sbjct: 1685 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1744
Query: 724 VATAKQVDFKQKISTLRNRVKT-TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
AT K+ + + +++ +R ++ K A + T + K + + E ++ ++
Sbjct: 1745 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804
Query: 783 NL----EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT--EVVRRNRDLIEA 836
L EE+K+Q Q + A+ E KT E+ + ++
Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1864
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD----RQ 892
+A+ E AF + + L+ + QH K ++ + ++++A+D +E+QK ++ D R+
Sbjct: 1865 RLRRLAEDE-AFQR-RRLEEQAAQH-KADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1921
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
+ ++I LK K K +L+ L ++ + T K+ E L + +L
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEAARQRQLAA 1977
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE-KKFREK 1003
+E ++ + QK+ A E + K E+E+ +K E ++ RE+
Sbjct: 1978 EEERRRREAEERVQKS--LAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2027
Score = 47.6 bits (108), Expect = 3e-04
Identities = 72/433 (16%), Positives = 166/433 (38%), Gaps = 13/433 (3%)
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
A +K + + ++L +K + E+ L ++ + D Q L+E ++ + E ++
Sbjct: 2165 AEMEKHKKFAEQTLRQKAQV--EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2222
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q+ ++ + ++E+ + + EA D + T + KQ
Sbjct: 2223 RS---QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2279
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
Q+ + L +++ A++ L + VQ+ L+ + LQ
Sbjct: 2280 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2339
Query: 799 XXXXXXXXXAITPLEVALKEKIEA--KTEVVRRNRDLIEAGSAYIAKVEVA-FNKVKSLD 855
+ L E+ + +T R R L + A K+ VA ++ ++
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2399
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT---DRQVLTKKIDTLKDEIAKQEVYK 912
E Q +K EK+ EK + T RQ + L++ IA+ E K
Sbjct: 2400 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREK 2459
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
L L + +++ +Q+ L E + + L+EK+SL+ ++ + Q+KA+
Sbjct: 2460 EKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2518
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ + R E ++ + +E++ + + + + + E + L +
Sbjct: 2519 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 1033 REKMENINMIIRE 1045
+++ + ++ E
Sbjct: 2578 QQRRQQEELLAEE 2590
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 9/174 (5%)
Query: 161 QEDSSWPLDEGKKVKERFDE----IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVK 216
++ + PL + + V+E+ + + + +++ + ++ ++ K Y +K E T K
Sbjct: 1231 EQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYK 1290
Query: 217 AKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
A+ + + KK E + E Y++ L SQ + I + ++ E +
Sbjct: 1291 AQLEPVASPAKK-PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1349
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+AE + E + E E A LEK L H K+QA+ E K+ Q + E
Sbjct: 1350 LAEQQRAEERERLAEVEAA----LEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1399
Score = 41.5 bits (93), Expect = 0.018
Identities = 91/632 (14%), Positives = 244/632 (38%), Gaps = 24/632 (3%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E +QE+ + + E Q+ Q++ +L+ +T + ++++++EE L +++
Sbjct: 1688 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1747
Query: 453 NKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIR 511
K + EL E + + + E E R+ L E +R
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807
Query: 512 ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE--KLQDEQNVLQSSMFIINKYK 569
E + + AE+ + + V K E +L+ E + N+
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQ-RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1866
Query: 570 GQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED-LQRASAKKDE 625
+L ++ L + +++++ + + + + ED L++ ++E
Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1926
Query: 626 ILSMKSLNEKITTLK---DTEIPQLEKRIVD-VDTQIKTLNETVEEITMSLIEPEQKMTT 681
IL++K+ EK K + E+ ++ D + ++ + E + ++ E ++
Sbjct: 1927 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1986
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLR 740
+++ + + ++ K ++ E +K + + + +A+Q+ Q+ + R
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 741 NRVKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSDCXX 797
+ + K+ LQ +++ ++L + + EE++ Q + +
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
E + + +A+ + ++ + + + A + ++ DAE
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2166
Query: 858 IQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
+++HKK + R+ ++++ L + ++ + +L +++ LK E + + +
Sbjct: 2167 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2226
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
++ L + Q + K + + + + + + + ++ + +Q AE LS
Sbjct: 2227 EEELFSVRVQME--ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2284
Query: 976 ELKKSLKGFRNELEKSLSKD---IEKKFREKM 1004
+ R E+ L++ EK +EKM
Sbjct: 2285 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2316
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKE--LEDSYKKNTSFNKEEEKIA 240
DA++ + + L++ ++ Q KLL+ + ++ Q+E L+++ SF E++ +
Sbjct: 2444 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2503
Query: 241 NEKSSNEIEYNKFILL------ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAE 293
+ E E K L ++Q + +R +Q +E + + ++ E + + EAE
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ E+++ L+ + Q+ EE ++
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
>AY480050-1|AAR95683.1| 4551|Homo sapiens plectin 10 protein.
Length = 4551
Score = 51.2 bits (117), Expect = 2e-05
Identities = 79/412 (19%), Positives = 174/412 (42%), Gaps = 27/412 (6%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
E+ +L+R K +E L ++ E++ K + EK+ + + + + + E+
Sbjct: 1629 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1688
Query: 670 MSLIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-----LD 723
EQ++ +Q+ G QE+ + + E ++Q ++ E+
Sbjct: 1689 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1748
Query: 724 VATAKQVDFKQKISTLRNRVKT-TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
AT K+ + + +++ +R ++ K A + T + K + + E ++ ++
Sbjct: 1749 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1808
Query: 783 NL----EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT--EVVRRNRDLIEA 836
L EE+K+Q Q + A+ E KT E+ + ++
Sbjct: 1809 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1868
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD----RQ 892
+A+ E AF + + L+ + QH K ++ + ++++A+D +E+QK ++ D R+
Sbjct: 1869 RLRRLAEDE-AFQR-RRLEEQAAQH-KADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1925
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
+ ++I LK K K +L+ L ++ + T K+ E L + +L
Sbjct: 1926 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEAARQRQLAA 1981
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE-KKFREK 1003
+E ++ + QK+ A E + K E+E+ +K E ++ RE+
Sbjct: 1982 EEERRRREAEERVQKS--LAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2031
Score = 47.6 bits (108), Expect = 3e-04
Identities = 72/433 (16%), Positives = 166/433 (38%), Gaps = 13/433 (3%)
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
A +K + + ++L +K + E+ L ++ + D Q L+E ++ + E ++
Sbjct: 2169 AEMEKHKKFAEQTLRQKAQV--EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2226
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q+ ++ + ++E+ + + EA D + T + KQ
Sbjct: 2227 RS---QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2283
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
Q+ + L +++ A++ L + VQ+ L+ + LQ
Sbjct: 2284 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2343
Query: 799 XXXXXXXXXAITPLEVALKEKIEA--KTEVVRRNRDLIEAGSAYIAKVEVA-FNKVKSLD 855
+ L E+ + +T R R L + A K+ VA ++ ++
Sbjct: 2344 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2403
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT---DRQVLTKKIDTLKDEIAKQEVYK 912
E Q +K EK+ EK + T RQ + L++ IA+ E K
Sbjct: 2404 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREK 2463
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
L L + +++ +Q+ L E + + L+EK+SL+ ++ + Q+KA+
Sbjct: 2464 EKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2522
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ + R E ++ + +E++ + + + + + E + L +
Sbjct: 2523 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2581
Query: 1033 REKMENINMIIRE 1045
+++ + ++ E
Sbjct: 2582 QQRRQQEELLAEE 2594
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 9/174 (5%)
Query: 161 QEDSSWPLDEGKKVKERFDE----IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVK 216
++ + PL + + V+E+ + + + +++ + ++ ++ K Y +K E T K
Sbjct: 1235 EQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYK 1294
Query: 217 AKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
A+ + + KK E + E Y++ L SQ + I + ++ E +
Sbjct: 1295 AQLEPVASPAKK-PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1353
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+AE + E + E E A LEK L H K+QA+ E K+ Q + E
Sbjct: 1354 LAEQQRAEERERLAEVEAA----LEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1403
Score = 41.5 bits (93), Expect = 0.018
Identities = 91/632 (14%), Positives = 244/632 (38%), Gaps = 24/632 (3%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E +QE+ + + E Q+ Q++ +L+ +T + ++++++EE L +++
Sbjct: 1692 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1751
Query: 453 NKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIR 511
K + EL E + + + E E R+ L E +R
Sbjct: 1752 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1811
Query: 512 ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE--KLQDEQNVLQSSMFIINKYK 569
E + + AE+ + + V K E +L+ E + N+
Sbjct: 1812 ALAEEAKRQRQLAEEDAARQ-RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1870
Query: 570 GQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED-LQRASAKKDE 625
+L ++ L + +++++ + + + + ED L++ ++E
Sbjct: 1871 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1930
Query: 626 ILSMKSLNEKITTLK---DTEIPQLEKRIVD-VDTQIKTLNETVEEITMSLIEPEQKMTT 681
IL++K+ EK K + E+ ++ D + ++ + E + ++ E ++
Sbjct: 1931 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1990
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLR 740
+++ + + ++ K ++ E +K + + + +A+Q+ Q+ + R
Sbjct: 1991 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2050
Query: 741 NRVKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSDCXX 797
+ + K+ LQ +++ ++L + + EE++ Q + +
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2110
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
E + + +A+ + ++ + + + A + ++ DAE
Sbjct: 2111 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2170
Query: 858 IQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
+++HKK + R+ ++++ L + ++ + +L +++ LK E + + +
Sbjct: 2171 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2230
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
++ L + Q + K + + + + + + + ++ + +Q AE LS
Sbjct: 2231 EEELFSVRVQME--ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2288
Query: 976 ELKKSLKGFRNELEKSLSKD---IEKKFREKM 1004
+ R E+ L++ EK +EKM
Sbjct: 2289 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2320
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKE--LEDSYKKNTSFNKEEEKIA 240
DA++ + + L++ ++ Q KLL+ + ++ Q+E L+++ SF E++ +
Sbjct: 2448 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2507
Query: 241 NEKSSNEIEYNKFILL------ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAE 293
+ E E K L ++Q + +R +Q +E + + ++ E + + EAE
Sbjct: 2508 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2567
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ E+++ L+ + Q+ EE ++
Sbjct: 2568 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2597
>AY480049-1|AAR95682.1| 4547|Homo sapiens plectin 8 protein.
Length = 4547
Score = 51.2 bits (117), Expect = 2e-05
Identities = 79/412 (19%), Positives = 174/412 (42%), Gaps = 27/412 (6%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
E+ +L+R K +E L ++ E++ K + EK+ + + + + + E+
Sbjct: 1625 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1684
Query: 670 MSLIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-----LD 723
EQ++ +Q+ G QE+ + + E ++Q ++ E+
Sbjct: 1685 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1744
Query: 724 VATAKQVDFKQKISTLRNRVKT-TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
AT K+ + + +++ +R ++ K A + T + K + + E ++ ++
Sbjct: 1745 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804
Query: 783 NL----EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT--EVVRRNRDLIEA 836
L EE+K+Q Q + A+ E KT E+ + ++
Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1864
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD----RQ 892
+A+ E AF + + L+ + QH K ++ + ++++A+D +E+QK ++ D R+
Sbjct: 1865 RLRRLAEDE-AFQR-RRLEEQAAQH-KADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1921
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
+ ++I LK K K +L+ L ++ + T K+ E L + +L
Sbjct: 1922 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEAARQRQLAA 1977
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE-KKFREK 1003
+E ++ + QK+ A E + K E+E+ +K E ++ RE+
Sbjct: 1978 EEERRRREAEERVQKS--LAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2027
Score = 47.6 bits (108), Expect = 3e-04
Identities = 72/433 (16%), Positives = 166/433 (38%), Gaps = 13/433 (3%)
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
A +K + + ++L +K + E+ L ++ + D Q L+E ++ + E ++
Sbjct: 2165 AEMEKHKKFAEQTLRQKAQV--EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2222
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q+ ++ + ++E+ + + EA D + T + KQ
Sbjct: 2223 RS---QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2279
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
Q+ + L +++ A++ L + VQ+ L+ + LQ
Sbjct: 2280 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2339
Query: 799 XXXXXXXXXAITPLEVALKEKIEA--KTEVVRRNRDLIEAGSAYIAKVEVA-FNKVKSLD 855
+ L E+ + +T R R L + A K+ VA ++ ++
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2399
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT---DRQVLTKKIDTLKDEIAKQEVYK 912
E Q +K EK+ EK + T RQ + L++ IA+ E K
Sbjct: 2400 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREK 2459
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
L L + +++ +Q+ L E + + L+EK+SL+ ++ + Q+KA+
Sbjct: 2460 EKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2518
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ + R E ++ + +E++ + + + + + E + L +
Sbjct: 2519 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2577
Query: 1033 REKMENINMIIRE 1045
+++ + ++ E
Sbjct: 2578 QQRRQQEELLAEE 2590
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 9/174 (5%)
Query: 161 QEDSSWPLDEGKKVKERFDE----IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVK 216
++ + PL + + V+E+ + + + +++ + ++ ++ K Y +K E T K
Sbjct: 1231 EQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYK 1290
Query: 217 AKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
A+ + + KK E + E Y++ L SQ + I + ++ E +
Sbjct: 1291 AQLEPVASPAKK-PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1349
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+AE + E + E E A LEK L H K+QA+ E K+ Q + E
Sbjct: 1350 LAEQQRAEERERLAEVEAA----LEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1399
Score = 41.5 bits (93), Expect = 0.018
Identities = 91/632 (14%), Positives = 244/632 (38%), Gaps = 24/632 (3%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E +QE+ + + E Q+ Q++ +L+ +T + ++++++EE L +++
Sbjct: 1688 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1747
Query: 453 NKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIR 511
K + EL E + + + E E R+ L E +R
Sbjct: 1748 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1807
Query: 512 ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE--KLQDEQNVLQSSMFIINKYK 569
E + + AE+ + + V K E +L+ E + N+
Sbjct: 1808 ALAEEAKRQRQLAEEDAARQ-RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1866
Query: 570 GQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED-LQRASAKKDE 625
+L ++ L + +++++ + + + + ED L++ ++E
Sbjct: 1867 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1926
Query: 626 ILSMKSLNEKITTLK---DTEIPQLEKRIVD-VDTQIKTLNETVEEITMSLIEPEQKMTT 681
IL++K+ EK K + E+ ++ D + ++ + E + ++ E ++
Sbjct: 1927 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1986
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLR 740
+++ + + ++ K ++ E +K + + + +A+Q+ Q+ + R
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 741 NRVKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSDCXX 797
+ + K+ LQ +++ ++L + + EE++ Q + +
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
E + + +A+ + ++ + + + A + ++ DAE
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2166
Query: 858 IQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
+++HKK + R+ ++++ L + ++ + +L +++ LK E + + +
Sbjct: 2167 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2226
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
++ L + Q + K + + + + + + + ++ + +Q AE LS
Sbjct: 2227 EEELFSVRVQME--ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2284
Query: 976 ELKKSLKGFRNELEKSLSKD---IEKKFREKM 1004
+ R E+ L++ EK +EKM
Sbjct: 2285 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2316
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKE--LEDSYKKNTSFNKEEEKIA 240
DA++ + + L++ ++ Q KLL+ + ++ Q+E L+++ SF E++ +
Sbjct: 2444 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2503
Query: 241 NEKSSNEIEYNKFILL------ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAE 293
+ E E K L ++Q + +R +Q +E + + ++ E + + EAE
Sbjct: 2504 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2563
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ E+++ L+ + Q+ EE ++
Sbjct: 2564 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2593
>AY480048-1|AAR95681.1| 4515|Homo sapiens plectin 7 protein.
Length = 4515
Score = 51.2 bits (117), Expect = 2e-05
Identities = 79/412 (19%), Positives = 174/412 (42%), Gaps = 27/412 (6%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
E+ +L+R K +E L ++ E++ K + EK+ + + + + + E+
Sbjct: 1593 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1652
Query: 670 MSLIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-----LD 723
EQ++ +Q+ G QE+ + + E ++Q ++ E+
Sbjct: 1653 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1712
Query: 724 VATAKQVDFKQKISTLRNRVKT-TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
AT K+ + + +++ +R ++ K A + T + K + + E ++ ++
Sbjct: 1713 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1772
Query: 783 NL----EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT--EVVRRNRDLIEA 836
L EE+K+Q Q + A+ E KT E+ + ++
Sbjct: 1773 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1832
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD----RQ 892
+A+ E AF + + L+ + QH K ++ + ++++A+D +E+QK ++ D R+
Sbjct: 1833 RLRRLAEDE-AFQR-RRLEEQAAQH-KADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1889
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
+ ++I LK K K +L+ L ++ + T K+ E L + +L
Sbjct: 1890 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEAARQRQLAA 1945
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE-KKFREK 1003
+E ++ + QK+ A E + K E+E+ +K E ++ RE+
Sbjct: 1946 EEERRRREAEERVQKS--LAAEEEAARQRKAALEEVERLKAKVEEARRLRER 1995
Score = 47.6 bits (108), Expect = 3e-04
Identities = 72/433 (16%), Positives = 166/433 (38%), Gaps = 13/433 (3%)
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
A +K + + ++L +K + E+ L ++ + D Q L+E ++ + E ++
Sbjct: 2133 AEMEKHKKFAEQTLRQKAQV--EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2190
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q+ ++ + ++E+ + + EA D + T + KQ
Sbjct: 2191 RS---QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2247
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
Q+ + L +++ A++ L + VQ+ L+ + LQ
Sbjct: 2248 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2307
Query: 799 XXXXXXXXXAITPLEVALKEKIEA--KTEVVRRNRDLIEAGSAYIAKVEVA-FNKVKSLD 855
+ L E+ + +T R R L + A K+ VA ++ ++
Sbjct: 2308 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2367
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT---DRQVLTKKIDTLKDEIAKQEVYK 912
E Q +K EK+ EK + T RQ + L++ IA+ E K
Sbjct: 2368 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREK 2427
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
L L + +++ +Q+ L E + + L+EK+SL+ ++ + Q+KA+
Sbjct: 2428 EKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2486
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ + R E ++ + +E++ + + + + + E + L +
Sbjct: 2487 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2545
Query: 1033 REKMENINMIIRE 1045
+++ + ++ E
Sbjct: 2546 QQRRQQEELLAEE 2558
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 9/174 (5%)
Query: 161 QEDSSWPLDEGKKVKERFDE----IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVK 216
++ + PL + + V+E+ + + + +++ + ++ ++ K Y +K E T K
Sbjct: 1199 EQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYK 1258
Query: 217 AKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
A+ + + KK E + E Y++ L SQ + I + ++ E +
Sbjct: 1259 AQLEPVASPAKK-PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1317
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+AE + E + E E A LEK L H K+QA+ E K+ Q + E
Sbjct: 1318 LAEQQRAEERERLAEVEAA----LEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1367
Score = 41.5 bits (93), Expect = 0.018
Identities = 91/632 (14%), Positives = 244/632 (38%), Gaps = 24/632 (3%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E +QE+ + + E Q+ Q++ +L+ +T + ++++++EE L +++
Sbjct: 1656 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1715
Query: 453 NKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIR 511
K + EL E + + + E E R+ L E +R
Sbjct: 1716 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1775
Query: 512 ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE--KLQDEQNVLQSSMFIINKYK 569
E + + AE+ + + V K E +L+ E + N+
Sbjct: 1776 ALAEEAKRQRQLAEEDAARQ-RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1834
Query: 570 GQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED-LQRASAKKDE 625
+L ++ L + +++++ + + + + ED L++ ++E
Sbjct: 1835 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1894
Query: 626 ILSMKSLNEKITTLK---DTEIPQLEKRIVD-VDTQIKTLNETVEEITMSLIEPEQKMTT 681
IL++K+ EK K + E+ ++ D + ++ + E + ++ E ++
Sbjct: 1895 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1954
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLR 740
+++ + + ++ K ++ E +K + + + +A+Q+ Q+ + R
Sbjct: 1955 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2014
Query: 741 NRVKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSDCXX 797
+ + K+ LQ +++ ++L + + EE++ Q + +
Sbjct: 2015 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2074
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
E + + +A+ + ++ + + + A + ++ DAE
Sbjct: 2075 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2134
Query: 858 IQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
+++HKK + R+ ++++ L + ++ + +L +++ LK E + + +
Sbjct: 2135 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2194
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
++ L + Q + K + + + + + + + ++ + +Q AE LS
Sbjct: 2195 EEELFSVRVQME--ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2252
Query: 976 ELKKSLKGFRNELEKSLSKD---IEKKFREKM 1004
+ R E+ L++ EK +EKM
Sbjct: 2253 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2284
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKE--LEDSYKKNTSFNKEEEKIA 240
DA++ + + L++ ++ Q KLL+ + ++ Q+E L+++ SF E++ +
Sbjct: 2412 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2471
Query: 241 NEKSSNEIEYNKFILL------ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAE 293
+ E E K L ++Q + +R +Q +E + + ++ E + + EAE
Sbjct: 2472 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2531
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ E+++ L+ + Q+ EE ++
Sbjct: 2532 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2561
>AY480047-1|AAR95680.1| 4684|Homo sapiens plectin 6 protein.
Length = 4684
Score = 51.2 bits (117), Expect = 2e-05
Identities = 79/412 (19%), Positives = 174/412 (42%), Gaps = 27/412 (6%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
E+ +L+R K +E L ++ E++ K + EK+ + + + + + E+
Sbjct: 1762 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1821
Query: 670 MSLIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-----LD 723
EQ++ +Q+ G QE+ + + E ++Q ++ E+
Sbjct: 1822 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1881
Query: 724 VATAKQVDFKQKISTLRNRVKT-TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
AT K+ + + +++ +R ++ K A + T + K + + E ++ ++
Sbjct: 1882 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1941
Query: 783 NL----EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT--EVVRRNRDLIEA 836
L EE+K+Q Q + A+ E KT E+ + ++
Sbjct: 1942 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 2001
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD----RQ 892
+A+ E AF + + L+ + QH K ++ + ++++A+D +E+QK ++ D R+
Sbjct: 2002 RLRRLAEDE-AFQR-RRLEEQAAQH-KADIEERLAQLRKASDSELERQKGLVEDTLRQRR 2058
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
+ ++I LK K K +L+ L ++ + T K+ E L + +L
Sbjct: 2059 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEAARQRQLAA 2114
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE-KKFREK 1003
+E ++ + QK+ A E + K E+E+ +K E ++ RE+
Sbjct: 2115 EEERRRREAEERVQKS--LAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2164
Score = 47.6 bits (108), Expect = 3e-04
Identities = 72/433 (16%), Positives = 166/433 (38%), Gaps = 13/433 (3%)
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
A +K + + ++L +K + E+ L ++ + D Q L+E ++ + E ++
Sbjct: 2302 AEMEKHKKFAEQTLRQKAQV--EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2359
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q+ ++ + ++E+ + + EA D + T + KQ
Sbjct: 2360 RS---QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2416
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
Q+ + L +++ A++ L + VQ+ L+ + LQ
Sbjct: 2417 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2476
Query: 799 XXXXXXXXXAITPLEVALKEKIEA--KTEVVRRNRDLIEAGSAYIAKVEVA-FNKVKSLD 855
+ L E+ + +T R R L + A K+ VA ++ ++
Sbjct: 2477 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2536
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT---DRQVLTKKIDTLKDEIAKQEVYK 912
E Q +K EK+ EK + T RQ + L++ IA+ E K
Sbjct: 2537 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREK 2596
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
L L + +++ +Q+ L E + + L+EK+SL+ ++ + Q+KA+
Sbjct: 2597 EKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2655
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ + R E ++ + +E++ + + + + + E + L +
Sbjct: 2656 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2714
Query: 1033 REKMENINMIIRE 1045
+++ + ++ E
Sbjct: 2715 QQRRQQEELLAEE 2727
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 9/174 (5%)
Query: 161 QEDSSWPLDEGKKVKERFDE----IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVK 216
++ + PL + + V+E+ + + + +++ + ++ ++ K Y +K E T K
Sbjct: 1368 EQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYK 1427
Query: 217 AKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
A+ + + KK E + E Y++ L SQ + I + ++ E +
Sbjct: 1428 AQLEPVASPAKK-PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1486
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+AE + E + E E A LEK L H K+QA+ E K+ Q + E
Sbjct: 1487 LAEQQRAEERERLAEVEAA----LEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1536
Score = 41.5 bits (93), Expect = 0.018
Identities = 91/632 (14%), Positives = 244/632 (38%), Gaps = 24/632 (3%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E +QE+ + + E Q+ Q++ +L+ +T + ++++++EE L +++
Sbjct: 1825 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1884
Query: 453 NKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIR 511
K + EL E + + + E E R+ L E +R
Sbjct: 1885 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1944
Query: 512 ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE--KLQDEQNVLQSSMFIINKYK 569
E + + AE+ + + V K E +L+ E + N+
Sbjct: 1945 ALAEEAKRQRQLAEEDAARQ-RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 2003
Query: 570 GQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED-LQRASAKKDE 625
+L ++ L + +++++ + + + + ED L++ ++E
Sbjct: 2004 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 2063
Query: 626 ILSMKSLNEKITTLK---DTEIPQLEKRIVD-VDTQIKTLNETVEEITMSLIEPEQKMTT 681
IL++K+ EK K + E+ ++ D + ++ + E + ++ E ++
Sbjct: 2064 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 2123
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLR 740
+++ + + ++ K ++ E +K + + + +A+Q+ Q+ + R
Sbjct: 2124 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2183
Query: 741 NRVKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSDCXX 797
+ + K+ LQ +++ ++L + + EE++ Q + +
Sbjct: 2184 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2243
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
E + + +A+ + ++ + + + A + ++ DAE
Sbjct: 2244 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2303
Query: 858 IQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
+++HKK + R+ ++++ L + ++ + +L +++ LK E + + +
Sbjct: 2304 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2363
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
++ L + Q + K + + + + + + + ++ + +Q AE LS
Sbjct: 2364 EEELFSVRVQME--ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2421
Query: 976 ELKKSLKGFRNELEKSLSKD---IEKKFREKM 1004
+ R E+ L++ EK +EKM
Sbjct: 2422 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2453
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKE--LEDSYKKNTSFNKEEEKIA 240
DA++ + + L++ ++ Q KLL+ + ++ Q+E L+++ SF E++ +
Sbjct: 2581 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2640
Query: 241 NEKSSNEIEYNKFILL------ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAE 293
+ E E K L ++Q + +R +Q +E + + ++ E + + EAE
Sbjct: 2641 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2700
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ E+++ L+ + Q+ EE ++
Sbjct: 2701 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2730
>AY480046-1|AAR95679.1| 4525|Homo sapiens plectin 3 protein.
Length = 4525
Score = 51.2 bits (117), Expect = 2e-05
Identities = 79/412 (19%), Positives = 174/412 (42%), Gaps = 27/412 (6%)
Query: 610 EKVTEDLQRASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEIT 669
E+ +L+R K +E L ++ E++ K + EK+ + + + + + E+
Sbjct: 1603 EEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1662
Query: 670 MSLIEPEQKMTTAKQI-HGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMT-----LD 723
EQ++ +Q+ G QE+ + + E ++Q ++ E+
Sbjct: 1663 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1722
Query: 724 VATAKQVDFKQKISTLRNRVKT-TQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIV 782
AT K+ + + +++ +R ++ K A + T + K + + E ++ ++
Sbjct: 1723 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1782
Query: 783 NL----EESKKQLQSDCXXXXXXXXXXXXAITPLEVALKEKIEAKT--EVVRRNRDLIEA 836
L EE+K+Q Q + A+ E KT E+ + ++
Sbjct: 1783 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1842
Query: 837 GSAYIAKVEVAFNKVKSLDAEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMTD----RQ 892
+A+ E AF + + L+ + QH K ++ + ++++A+D +E+QK ++ D R+
Sbjct: 1843 RLRRLAEDE-AFQR-RRLEEQAAQH-KADIEERLAQLRKASDSELERQKGLVEDTLRQRR 1899
Query: 893 VLTKKIDTLKDEIAKQEVYKRDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNE 952
+ ++I LK K K +L+ L ++ + T K+ E L + +L
Sbjct: 1900 QVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAE----LEAARQRQLAA 1955
Query: 953 KESLIIKQTKLFQQKAECTGALSELKKSLKGFRNELEKSLSKDIE-KKFREK 1003
+E ++ + QK+ A E + K E+E+ +K E ++ RE+
Sbjct: 1956 EEERRRREAEERVQKS--LAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2005
Score = 47.6 bits (108), Expect = 3e-04
Identities = 72/433 (16%), Positives = 166/433 (38%), Gaps = 13/433 (3%)
Query: 619 ASAKKDEILSMKSLNEKITTLKDTEIPQLEKRIVDVDTQIKTLNETVEEITMSLIEPEQK 678
A +K + + ++L +K + E+ L ++ + D Q L+E ++ + E ++
Sbjct: 2143 AEMEKHKKFAEQTLRQKAQV--EQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQ 2200
Query: 679 MTTAKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDSEMTLDVATAKQVDFKQKIST 738
+ Q+ ++ + ++E+ + + EA D + T + KQ
Sbjct: 2201 RS---QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEE 2257
Query: 739 LRNRVKTTQKKLNAHNKKLQTLYEKKTKAKEELLNTQKKVQDIVNLEESKKQLQSDCXXX 798
Q+ + L +++ A++ L + VQ+ L+ + LQ
Sbjct: 2258 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2317
Query: 799 XXXXXXXXXAITPLEVALKEKIEA--KTEVVRRNRDLIEAGSAYIAKVEVA-FNKVKSLD 855
+ L E+ + +T R R L + A K+ VA ++ ++
Sbjct: 2318 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA 2377
Query: 856 AEIQQHKKKNVPREMEKIQEANDKLMEKQKQIMT---DRQVLTKKIDTLKDEIAKQEVYK 912
E Q +K EK+ EK + T RQ + L++ IA+ E K
Sbjct: 2378 EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREK 2437
Query: 913 RDLDDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTG 972
L L + +++ +Q+ L E + + L+EK+SL+ ++ + Q+KA+
Sbjct: 2438 EKLQQEAKLLQLKSEEMQTVQQEQLLQET-QALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2496
Query: 973 ALSELKKSLKGFRNELEKSLSKDIEKKFREKMYELHVTKAIDKDIREYAVALDKCLMEFH 1032
+ + R E ++ + +E++ + + + + + E + L +
Sbjct: 2497 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLE 2555
Query: 1033 REKMENINMIIRE 1045
+++ + ++ E
Sbjct: 2556 QQRRQQEELLAEE 2568
Score = 46.0 bits (104), Expect = 8e-04
Identities = 39/174 (22%), Positives = 76/174 (43%), Gaps = 9/174 (5%)
Query: 161 QEDSSWPLDEGKKVKERFDE----IFDADKYSDCLDRLKKIRKDYAQNLKLLENYATTVK 216
++ + PL + + V+E+ + + + +++ + ++ ++ K Y +K E T K
Sbjct: 1209 EQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYK 1268
Query: 217 AKQKELEDSYKKNTSFNKEEEKIANEKSSNEIEYNKFILLESQNQEKIDKRNEQIVETAK 276
A+ + + KK E + E Y++ L SQ + I + ++ E +
Sbjct: 1269 AQLEPVASPAKK-PKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1327
Query: 277 IAEIENITEVQTNEEAENATKTILEKVESLKSDHKVQKSQADEEEKKAQGFVDE 330
+AE + E + E E A LEK L H K+QA+ E K+ Q + E
Sbjct: 1328 LAEQQRAEERERLAEVEAA----LEKQRQLAEAHAQAKAQAEREAKELQQRMQE 1377
Score = 41.5 bits (93), Expect = 0.018
Identities = 91/632 (14%), Positives = 244/632 (38%), Gaps = 24/632 (3%)
Query: 394 EECQQEINEDEKAVEQYEQEMDELSQKITKLQKQTAK-LKEKEMIEENLKTKEKQLIVLK 452
E +QE+ + + E Q+ Q++ +L+ +T + ++++++EE L +++
Sbjct: 1666 ELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAAT 1725
Query: 453 NKHKTALMELLGNVPEKDFAVTIN-KFECEVRNEVXXXXXXXXXXXXXXXXLEAERKHIR 511
K + EL E + + + E E R+ L E +R
Sbjct: 1726 QKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLR 1785
Query: 512 ESLNERRSELTKAEDKIYKACGTQPYDVTLSKYTTTVE--KLQDEQNVLQSSMFIINKYK 569
E + + AE+ + + V K E +L+ E + N+
Sbjct: 1786 ALAEEAKRQRQLAEEDAARQ-RAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERL 1844
Query: 570 GQLKDNSCCP---LCNRGFENESEXXXXXXXXXXXXMNVPGKLEKVTED-LQRASAKKDE 625
+L ++ L + +++++ + + + + ED L++ ++E
Sbjct: 1845 RRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEE 1904
Query: 626 ILSMKSLNEKITTLK---DTEIPQLEKRIVD-VDTQIKTLNETVEEITMSLIEPEQKMTT 681
IL++K+ EK K + E+ ++ D + ++ + E + ++ E ++
Sbjct: 1905 ILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1964
Query: 682 AKQIHGDMPMLDRYIQEIKTVTKKFEAVKEQCGDVDS-EMTLDVATAKQVDFKQKISTLR 740
+++ + + ++ K ++ E +K + + + +A+Q+ Q+ + R
Sbjct: 1965 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2024
Query: 741 NRVKTTQKKLNAHNKK--LQTLYEKKTKAKEELLNTQKKVQDIVN-LEESKKQLQSDCXX 797
+ + K+ LQ +++ ++L + + EE++ Q + +
Sbjct: 2025 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2084
Query: 798 XXXXXXXXXXAITPLEVALKEKIEAKTEVVRRNRDLIEAGSAYIAKVEVAFNKVKSLDAE 857
E + + +A+ + ++ + + + A + ++ DAE
Sbjct: 2085 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2144
Query: 858 IQQHKK--KNVPREMEKIQEANDKLMEKQKQIMTDRQVLTKKIDTLKDEIAKQEVYKRDL 915
+++HKK + R+ ++++ L + ++ + +L +++ LK E + + +
Sbjct: 2145 MEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQV 2204
Query: 916 DDNLCLRKAQTDITNWQKQDDELNEKLNGINKEELNEKESLIIKQTKLFQQKAECTGALS 975
++ L + Q + K + + + + + + + ++ + +Q AE LS
Sbjct: 2205 EEELFSVRVQME--ELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2262
Query: 976 ELKKSLKGFRNELEKSLSKD---IEKKFREKM 1004
+ R E+ L++ EK +EKM
Sbjct: 2263 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKM 2294
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/150 (20%), Positives = 71/150 (47%), Gaps = 9/150 (6%)
Query: 183 DADKYSDCLDRLKKIRKDYAQNLKLLENYATTVKAKQKE--LEDSYKKNTSFNKEEEKIA 240
DA++ + + L++ ++ Q KLL+ + ++ Q+E L+++ SF E++ +
Sbjct: 2422 DAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLL 2481
Query: 241 NEKSSNEIEYNKFILL------ESQNQEKIDKRNEQIVETAKIAEIENITEVQTNE-EAE 293
+ E E K L ++Q + +R +Q +E + + ++ E + + EAE
Sbjct: 2482 QRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAE 2541
Query: 294 NATKTILEKVESLKSDHKVQKSQADEEEKK 323
+ E+++ L+ + Q+ EE ++
Sbjct: 2542 EGVRRKQEELQQLEQQRRQQEELLAEENQR 2571
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.311 0.128 0.342
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 134,694,476
Number of Sequences: 224733
Number of extensions: 5293096
Number of successful extensions: 47323
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 1503
Number of HSP's that attempted gapping in prelim test: 35521
Number of HSP's gapped (non-prelim): 11856
length of query: 1199
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1101
effective length of database: 51,211,004
effective search space: 56383315404
effective search space used: 56383315404
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.8 bits)
S2: 71 (32.7 bits)
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