Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005382-TA|BGIBMGA005382-PA|IPR002857|Zinc finger,
CXXC-type, IPR001025|Bromo adjacent region, IPR001525|C-5
cytosine-specific DNA methylase
(1314 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X63692-1|CAA45219.1| 1616|Homo sapiens DNA (cytosine-5-)-methylt... 1029 0.0
BC126227-1|AAI26228.1| 1632|Homo sapiens DNMT1 protein protein. 1029 0.0
BC092517-1|AAH92517.1| 1511|Homo sapiens DNMT1 protein protein. 1029 0.0
AF180682-1|AAF23609.1| 1280|Homo sapiens DNA (cytosine-5)-methyl... 1029 0.0
AB209413-1|BAD92650.1| 1606|Homo sapiens DNA (cytosine-5-)-methy... 1028 0.0
AC010077-1|AAD54507.1| 966|Homo sapiens MTDM_HUMAN [AA 1- 966] ... 487 e-136
BC115379-1|AAI15380.1| 559|Homo sapiens FBXL10 protein protein. 63 6e-09
BC115380-1|AAI15381.1| 706|Homo sapiens FBXL10 protein protein. 62 1e-08
AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein. 62 1e-08
AB031230-1|BAA97672.1| 827|Homo sapiens protein containing CXXC... 62 1e-08
BC064360-1|AAH64360.1| 1162|Homo sapiens F-box and leucine-rich ... 59 1e-07
BC047486-1|AAH47486.1| 782|Homo sapiens FBXL11 protein protein. 59 1e-07
BC047371-1|AAH47371.1| 856|Homo sapiens FBXL11 protein protein. 59 1e-07
AK024505-1|BAB15795.1| 757|Homo sapiens FLJ00115 protein protein. 59 1e-07
AB023221-1|BAA76848.2| 1163|Homo sapiens KIAA1004 protein protein. 59 1e-07
Z69744-1|CAA93625.1| 4005|Homo sapiens ALL-1 protein protein. 55 1e-06
L22179-1|AAC37520.1| 2311|Homo sapiens MLL-AF4 der(11) fusion pr... 55 1e-06
L04284-1|AAA58669.1| 3969|Homo sapiens HRX protein. 55 1e-06
D14540-1|BAA03407.1| 1909|Homo sapiens MLL protein. 55 1e-06
AY373585-1|AAQ63624.1| 3969|Homo sapiens myeloid/lymphoid or mix... 55 1e-06
AB209508-1|BAD92745.1| 2880|Homo sapiens myeloid/lymphoid or mix... 55 1e-06
AF272382-1|AAG31986.1| 316|Homo sapiens MLL protein protein. 53 6e-06
AF045888-1|AAC39764.1| 391|Homo sapiens putative DNA cytosine m... 51 3e-05
BC047733-1|AAH47733.1| 391|Homo sapiens tRNA aspartic acid meth... 50 4e-05
BC015733-1|AAH15733.1| 660|Homo sapiens CXXC1 protein protein. 50 4e-05
BC014940-1|AAH14940.1| 656|Homo sapiens CXXC finger 1 (PHD doma... 50 4e-05
AF149758-1|AAF37799.1| 656|Homo sapiens CpG binding protein pro... 50 4e-05
AB209883-1|BAD93120.1| 523|Homo sapiens CpG binding protein var... 50 4e-05
AB031069-1|BAA96307.1| 656|Homo sapiens protein containing CXXC... 50 4e-05
CR450316-1|CAG29312.1| 391|Homo sapiens DNMT2 protein. 50 6e-05
AL133415-5|CAB87964.1| 391|Homo sapiens DNA (cytosine-5-)-methy... 50 6e-05
AJ223333-1|CAA11272.1| 391|Homo sapiens DNA methyltransferase p... 50 6e-05
AJ007041-1|CAB45385.1| 2715|Homo sapiens trithorax homologue 2 p... 50 6e-05
AF186605-1|AAD56420.1| 2605|Homo sapiens MLL2 protein protein. 50 6e-05
AF104918-1|AAD17932.1| 1010|Homo sapiens myeloid/lymphoid leukem... 50 6e-05
AF012128-1|AAC51939.1| 391|Homo sapiens putative DNA methyltran... 50 6e-05
AB002302-1|BAA20763.3| 2415|Homo sapiens KIAA0304 protein protein. 50 6e-05
EF488685-1|ABP02056.1| 536|Homo sapiens methyl-CpG binding doma... 45 0.002
AJ564845-1|CAD92308.1| 550|Homo sapiens methyl-CpG binding doma... 45 0.002
AF120981-1|AAD50371.1| 605|Homo sapiens methyl-CpG binding prot... 45 0.002
Y10746-1|CAA71735.1| 556|Homo sapiens methyl-CpG binding protei... 42 0.015
AF078831-1|AAD51443.1| 586|Homo sapiens methyl-CpG binding prot... 42 0.015
AF078830-1|AAD51442.1| 605|Homo sapiens methyl-CpG binding prot... 42 0.015
AL713888-4|CAI15118.1| 2136|Homo sapiens leukemia-associated pro... 40 0.078
AL513534-3|CAH70220.1| 2136|Homo sapiens leukemia-associated pro... 40 0.078
AF430147-1|AAM88301.1| 2136|Homo sapiens leukemia-associated pro... 40 0.078
AL133415-4|CAI39483.1| 134|Homo sapiens DNA (cytosine-5-)-methy... 38 0.32
AF329940-1|AAK68034.1| 137|Homo sapiens DNA methyltransferase 2... 38 0.32
BC119752-1|AAI19753.1| 198|Homo sapiens CXXC finger 4 protein. 37 0.55
BC119751-1|AAI19752.1| 198|Homo sapiens CXXC finger 4 protein. 37 0.55
BC033242-1|AAH33242.1| 549|Homo sapiens methyl-CpG binding doma... 37 0.55
AF272159-1|AAG42072.1| 198|Homo sapiens Dvl-binding protein IDA... 37 0.55
AF078833-1|AAD51445.1| 503|Homo sapiens methyl-CpG binding prot... 37 0.55
AF078832-1|AAD51444.1| 549|Homo sapiens methyl-CpG binding prot... 37 0.55
AC093628-1|AAY40933.1| 198|Homo sapiens unknown protein. 37 0.55
AB209765-1|BAD93002.1| 397|Homo sapiens methyl-CpG binding doma... 35 2.2
AF072241-1|AAC68870.1| 52|Homo sapiens methyl-CpG binding prot... 33 5.1
>X63692-1|CAA45219.1| 1616|Homo sapiens DNA
(cytosine-5-)-methyltransferase protein.
Length = 1616
Score = 1029 bits (2548), Expect = 0.0
Identities = 537/1191 (45%), Positives = 720/1191 (60%), Gaps = 44/1191 (3%)
Query: 133 KCNICGQFLNNSDLIYYQGHPQDAVEEYIALTNDKL-VLSSGEDG--DIMERPQTNITGF 189
KC CGQ+L++ DL Y Q HP DAV+E LTN+KL + + E G PQ +T F
Sbjct: 352 KCIQCGQYLDDPDLKYGQ-HPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCF 410
Query: 190 TIFDEQGHLCPIDGGLVENDVRIYMSGYLKXXXXXXXXXXXXXXPVKDVGPIIEWFIHGF 249
+++ + GHLCPID GL+E ++ ++ SG K K++GPI EW+I GF
Sbjct: 411 SVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNG-KNLGPINEWWITGF 469
Query: 250 DGGDRNCITLSTEFGEYNLLKPSEAYTPLMNNLYEKIWLSKVVVEFLEEYHYLQPSYEDL 309
DGG++ I ST F EY L+ PS Y P+ + EKI++SK+VVEFL+ +YEDL
Sbjct: 470 DGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNS--DSTYEDL 527
Query: 310 LEVVRDFSIPE-LNNKKMTEEMLHKHAQFVCDQVVSLEI--EEDDEPLITLPCMRELIKL 366
+ + P LN + TE+ L +HAQFV +QV S + + D++P+ PCMR+LIKL
Sbjct: 528 INKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKL 587
Query: 367 MGIKFGKRKIRTQIQYXXXXXXXX----XXXXXXPLVRKTFESFFSNQLDKTNHE---LV 419
G+ G+R+ + + Q LV + F++FF+ Q++K + E
Sbjct: 588 AGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENA 647
Query: 420 LRRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAEDSDPDDE 479
+R+RCGVCE CQ P+CG+C AC+ M KFGG GR+K+AC R CPNMA+++A+D + D+
Sbjct: 648 FKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDD 707
Query: 480 DEYQQISEKKQDKIDDAVPVKLTGSNSKNLKWIGEPVKADATKIYYEKVEIDGAELCNGD 539
+ + S KK + K N + W+GE VK D K YY+KV ID L GD
Sbjct: 708 NIPEMPSPKKMHQ------GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGD 761
Query: 540 FVMIETSQTNIPTLVAKVVYMWKEIHNPKSGYFHGEVFIRASDTVLGEVSDPREVFLGDR 599
V + ++ P +A+V +W++ N + FH F +DTVLG SDP E+FL D
Sbjct: 762 CVSVIPDDSSKPLYLARVTALWEDSSNGQM--FHAHWFCAGTDTVLGATSDPLELFLVDE 819
Query: 600 CCHGAPLSSILRKANIERKETSADWFKLGGKEVDDEHFEDDGRTYFYSKYYDRFTSRFED 659
C LS I K + K S +W GG + + DDG+TYFY +YD+ +RFE
Sbjct: 820 C-EDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFES 878
Query: 660 LPPDPACPNALRKHRFCPSCERKTKRDARNIPKVFEKLIVKSEIVSEQNRSEWSYVKWQD 719
P P K +FC SC R + + IP+V E+L V + ++ +
Sbjct: 879 --PPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGIL---- 932
Query: 720 FDYKKGCGVFLKPGTFKLKNSMTKANTVAKPRFEKVDETIYPEYYRKNDSNTRGSNIDTG 779
Y+ G GV+L P F ++ + V +PR E VDE +YPE+YRK +GSN+D
Sbjct: 933 --YRVGDGVYLPPEAFTFNIKLS--SPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAP 988
Query: 780 EPFCVGYIAAVTAASEGPLVVPQ-DIYLKVNVLLRPENTSSKFPQ--HEDTNVLYWTTEI 836
EP+ +G I + + + DI ++VN RPENT P H D N+LYW+ E
Sbjct: 989 EPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEE 1048
Query: 837 REIPFSTVVGHCHLIYEQNVPQNISLQEWLGNDPCRFYFRMAYCKSTGEFTDLPQNAISV 896
+ F V G C + Y +++P+ + + G P RFYF AY + F D P +A S
Sbjct: 1049 AVVDFKAVQGRCTVEYGEDLPECVQVYSMGG--PNRFYFLEAYNAKSKSFEDPPNHARSP 1106
Query: 897 XXXXXXXXXXXXXXXXXXXIETVPAKVVEEKIRPLRTLDVFAGCGGLSEGLHQAGVAECK 956
+ P +E K+ LRTLDVF+GCGGLSEG HQAG+++
Sbjct: 1107 GNKGKGKGKGKGKPKSQACEPSEPE--IEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTL 1164
Query: 957 WAIENVEAASHAYSLNNKSCIVFNEDCNALLKTVMSGAKHSANGLRLPMQGEVELLCGGP 1016
WAIE + A+ A+ LNN VF EDCN LLK VM+G ++ G RLP +G+VE+LCGGP
Sbjct: 1165 WAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGP 1224
Query: 1017 PCQGFSGMNRFNSREYSNFKNSLVASYLSFCDYYRPKYFILENVRNFVAFKKGMVLKLTL 1076
PCQGFSGMNRFNSR YS FKNSLV S+LS+CDYYRP++F+LENVRNFV+FK+ MVLKLTL
Sbjct: 1225 PCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTL 1284
Query: 1077 RALLDMGYQCTFGILQAGNYGVPQTRRRLIILAAAPGYNLPFYPEPTHVFSRRACTLTTT 1136
R L+ MGYQCTFG+LQAG YGV QTRRR IILAAAPG LP +PEP HVF+ RAC L+
Sbjct: 1285 RCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVV 1344
Query: 1137 IDGKRFSTNIHWDESAPKRTCTIQDAMSDLPQICNGANKIEIEYGSMPESHFQRLVRSND 1196
+D K+F +NI S P RT T++D MSDLP++ NGA+ +EI Y P+S FQR +R
Sbjct: 1345 VDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQ 1404
Query: 1197 ENSKLRDHICKNMAPLIQARISRIPTTPGSDWRDLPNISVTLSDGTKCKVLQYRYDDKRN 1256
LRDHICK+M+ L+ AR+ IP PGSDWRDLPNI V LSDGT + L+Y + D++N
Sbjct: 1405 YQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKN 1464
Query: 1257 GRSSSGAVRGVCACA-SGRACSPLDKQENTLIPWCLPHTGNRHNHWAGLYG 1306
GRSSSGA+RGVC+C +G+AC P +Q NTLIPWCLPHTGNRHNHWAGLYG
Sbjct: 1465 GRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYG 1515
>BC126227-1|AAI26228.1| 1632|Homo sapiens DNMT1 protein protein.
Length = 1632
Score = 1029 bits (2548), Expect = 0.0
Identities = 537/1191 (45%), Positives = 720/1191 (60%), Gaps = 44/1191 (3%)
Query: 133 KCNICGQFLNNSDLIYYQGHPQDAVEEYIALTNDKL-VLSSGEDG--DIMERPQTNITGF 189
KC CGQ+L++ DL Y Q HP DAV+E LTN+KL + + E G PQ +T F
Sbjct: 368 KCIQCGQYLDDPDLKYGQ-HPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCF 426
Query: 190 TIFDEQGHLCPIDGGLVENDVRIYMSGYLKXXXXXXXXXXXXXXPVKDVGPIIEWFIHGF 249
+++ + GHLCPID GL+E ++ ++ SG K K++GPI EW+I GF
Sbjct: 427 SVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNG-KNLGPINEWWITGF 485
Query: 250 DGGDRNCITLSTEFGEYNLLKPSEAYTPLMNNLYEKIWLSKVVVEFLEEYHYLQPSYEDL 309
DGG++ I ST F EY L+ PS Y P+ + EKI++SK+VVEFL+ +YEDL
Sbjct: 486 DGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNS--DSTYEDL 543
Query: 310 LEVVRDFSIPE-LNNKKMTEEMLHKHAQFVCDQVVSLEI--EEDDEPLITLPCMRELIKL 366
+ + P LN + TE+ L +HAQFV +QV S + + D++P+ PCMR+LIKL
Sbjct: 544 INKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKL 603
Query: 367 MGIKFGKRKIRTQIQYXXXXXXXX----XXXXXXPLVRKTFESFFSNQLDKTNHE---LV 419
G+ G+R+ + + Q LV + F++FF+ Q++K + E
Sbjct: 604 AGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENA 663
Query: 420 LRRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAEDSDPDDE 479
+R+RCGVCE CQ P+CG+C AC+ M KFGG GR+K+AC R CPNMA+++A+D + D+
Sbjct: 664 FKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDD 723
Query: 480 DEYQQISEKKQDKIDDAVPVKLTGSNSKNLKWIGEPVKADATKIYYEKVEIDGAELCNGD 539
+ + S KK + K N + W+GE VK D K YY+KV ID L GD
Sbjct: 724 NIPEMPSPKKMHQ------GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGD 777
Query: 540 FVMIETSQTNIPTLVAKVVYMWKEIHNPKSGYFHGEVFIRASDTVLGEVSDPREVFLGDR 599
V + ++ P +A+V +W++ N + FH F +DTVLG SDP E+FL D
Sbjct: 778 CVSVIPDDSSKPLYLARVTALWEDSSNGQM--FHAHWFCAGTDTVLGATSDPLELFLVDE 835
Query: 600 CCHGAPLSSILRKANIERKETSADWFKLGGKEVDDEHFEDDGRTYFYSKYYDRFTSRFED 659
C LS I K + K S +W GG + + DDG+TYFY +YD+ +RFE
Sbjct: 836 C-EDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFES 894
Query: 660 LPPDPACPNALRKHRFCPSCERKTKRDARNIPKVFEKLIVKSEIVSEQNRSEWSYVKWQD 719
P P K +FC SC R + + IP+V E+L V + ++ +
Sbjct: 895 --PPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGIL---- 948
Query: 720 FDYKKGCGVFLKPGTFKLKNSMTKANTVAKPRFEKVDETIYPEYYRKNDSNTRGSNIDTG 779
Y+ G GV+L P F ++ + V +PR E VDE +YPE+YRK +GSN+D
Sbjct: 949 --YRVGDGVYLPPEAFTFNIKLS--SPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAP 1004
Query: 780 EPFCVGYIAAVTAASEGPLVVPQ-DIYLKVNVLLRPENTSSKFPQ--HEDTNVLYWTTEI 836
EP+ +G I + + + DI ++VN RPENT P H D N+LYW+ E
Sbjct: 1005 EPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEE 1064
Query: 837 REIPFSTVVGHCHLIYEQNVPQNISLQEWLGNDPCRFYFRMAYCKSTGEFTDLPQNAISV 896
+ F V G C + Y +++P+ + + G P RFYF AY + F D P +A S
Sbjct: 1065 AVVDFKAVQGRCTVEYGEDLPECVQVYSMGG--PNRFYFLEAYNAKSKSFEDPPNHARSP 1122
Query: 897 XXXXXXXXXXXXXXXXXXXIETVPAKVVEEKIRPLRTLDVFAGCGGLSEGLHQAGVAECK 956
+ P +E K+ LRTLDVF+GCGGLSEG HQAG+++
Sbjct: 1123 GNKGKGKGKGKGKPKSQACEPSEPE--IEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTL 1180
Query: 957 WAIENVEAASHAYSLNNKSCIVFNEDCNALLKTVMSGAKHSANGLRLPMQGEVELLCGGP 1016
WAIE + A+ A+ LNN VF EDCN LLK VM+G ++ G RLP +G+VE+LCGGP
Sbjct: 1181 WAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGP 1240
Query: 1017 PCQGFSGMNRFNSREYSNFKNSLVASYLSFCDYYRPKYFILENVRNFVAFKKGMVLKLTL 1076
PCQGFSGMNRFNSR YS FKNSLV S+LS+CDYYRP++F+LENVRNFV+FK+ MVLKLTL
Sbjct: 1241 PCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTL 1300
Query: 1077 RALLDMGYQCTFGILQAGNYGVPQTRRRLIILAAAPGYNLPFYPEPTHVFSRRACTLTTT 1136
R L+ MGYQCTFG+LQAG YGV QTRRR IILAAAPG LP +PEP HVF+ RAC L+
Sbjct: 1301 RCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVV 1360
Query: 1137 IDGKRFSTNIHWDESAPKRTCTIQDAMSDLPQICNGANKIEIEYGSMPESHFQRLVRSND 1196
+D K+F +NI S P RT T++D MSDLP++ NGA+ +EI Y P+S FQR +R
Sbjct: 1361 VDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQ 1420
Query: 1197 ENSKLRDHICKNMAPLIQARISRIPTTPGSDWRDLPNISVTLSDGTKCKVLQYRYDDKRN 1256
LRDHICK+M+ L+ AR+ IP PGSDWRDLPNI V LSDGT + L+Y + D++N
Sbjct: 1421 YQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKN 1480
Query: 1257 GRSSSGAVRGVCACA-SGRACSPLDKQENTLIPWCLPHTGNRHNHWAGLYG 1306
GRSSSGA+RGVC+C +G+AC P +Q NTLIPWCLPHTGNRHNHWAGLYG
Sbjct: 1481 GRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYG 1531
>BC092517-1|AAH92517.1| 1511|Homo sapiens DNMT1 protein protein.
Length = 1511
Score = 1029 bits (2548), Expect = 0.0
Identities = 537/1191 (45%), Positives = 720/1191 (60%), Gaps = 44/1191 (3%)
Query: 133 KCNICGQFLNNSDLIYYQGHPQDAVEEYIALTNDKL-VLSSGEDG--DIMERPQTNITGF 189
KC CGQ+L++ DL Y Q HP DAV+E LTN+KL + + E G PQ +T F
Sbjct: 247 KCIQCGQYLDDPDLKYGQ-HPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCF 305
Query: 190 TIFDEQGHLCPIDGGLVENDVRIYMSGYLKXXXXXXXXXXXXXXPVKDVGPIIEWFIHGF 249
+++ + GHLCPID GL+E ++ ++ SG K K++GPI EW+I GF
Sbjct: 306 SVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNG-KNLGPINEWWITGF 364
Query: 250 DGGDRNCITLSTEFGEYNLLKPSEAYTPLMNNLYEKIWLSKVVVEFLEEYHYLQPSYEDL 309
DGG++ I ST F EY L+ PS Y P+ + EKI++SK+VVEFL+ +YEDL
Sbjct: 365 DGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNS--DSTYEDL 422
Query: 310 LEVVRDFSIPE-LNNKKMTEEMLHKHAQFVCDQVVSLEI--EEDDEPLITLPCMRELIKL 366
+ + P LN + TE+ L +HAQFV +QV S + + D++P+ PCMR+LIKL
Sbjct: 423 INKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKL 482
Query: 367 MGIKFGKRKIRTQIQYXXXXXXXX----XXXXXXPLVRKTFESFFSNQLDKTNHE---LV 419
G+ G+R+ + + Q LV + F++FF+ Q++K + E
Sbjct: 483 AGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENA 542
Query: 420 LRRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAEDSDPDDE 479
+R+RCGVCE CQ P+CG+C AC+ M KFGG GR+K+AC R CPNMA+++A+D + D+
Sbjct: 543 FKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDD 602
Query: 480 DEYQQISEKKQDKIDDAVPVKLTGSNSKNLKWIGEPVKADATKIYYEKVEIDGAELCNGD 539
+ + S KK + K N + W+GE VK D K YY+KV ID L GD
Sbjct: 603 NIPEMPSPKKMHQ------GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGD 656
Query: 540 FVMIETSQTNIPTLVAKVVYMWKEIHNPKSGYFHGEVFIRASDTVLGEVSDPREVFLGDR 599
V + ++ P +A+V +W++ N + FH F +DTVLG SDP E+FL D
Sbjct: 657 CVSVIPDDSSKPLYLARVTALWEDSSNGQM--FHAHWFCAGTDTVLGATSDPLELFLVDE 714
Query: 600 CCHGAPLSSILRKANIERKETSADWFKLGGKEVDDEHFEDDGRTYFYSKYYDRFTSRFED 659
C LS I K + K S +W GG + + DDG+TYFY +YD+ +RFE
Sbjct: 715 C-EDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFES 773
Query: 660 LPPDPACPNALRKHRFCPSCERKTKRDARNIPKVFEKLIVKSEIVSEQNRSEWSYVKWQD 719
P P K +FC SC R + + IP+V E+L V + ++ +
Sbjct: 774 --PPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGIL---- 827
Query: 720 FDYKKGCGVFLKPGTFKLKNSMTKANTVAKPRFEKVDETIYPEYYRKNDSNTRGSNIDTG 779
Y+ G GV+L P F ++ + V +PR E VDE +YPE+YRK +GSN+D
Sbjct: 828 --YRVGDGVYLPPEAFTFNIKLS--SPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAP 883
Query: 780 EPFCVGYIAAVTAASEGPLVVPQ-DIYLKVNVLLRPENTSSKFPQ--HEDTNVLYWTTEI 836
EP+ +G I + + + DI ++VN RPENT P H D N+LYW+ E
Sbjct: 884 EPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEE 943
Query: 837 REIPFSTVVGHCHLIYEQNVPQNISLQEWLGNDPCRFYFRMAYCKSTGEFTDLPQNAISV 896
+ F V G C + Y +++P+ + + G P RFYF AY + F D P +A S
Sbjct: 944 AVVDFKAVQGRCTVEYGEDLPECVQVYSMGG--PNRFYFLEAYNAKSKSFEDPPNHARSP 1001
Query: 897 XXXXXXXXXXXXXXXXXXXIETVPAKVVEEKIRPLRTLDVFAGCGGLSEGLHQAGVAECK 956
+ P +E K+ LRTLDVF+GCGGLSEG HQAG+++
Sbjct: 1002 GNKGKGKGKGKGKPKSQACEPSEPE--IEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTL 1059
Query: 957 WAIENVEAASHAYSLNNKSCIVFNEDCNALLKTVMSGAKHSANGLRLPMQGEVELLCGGP 1016
WAIE + A+ A+ LNN VF EDCN LLK VM+G ++ G RLP +G+VE+LCGGP
Sbjct: 1060 WAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGP 1119
Query: 1017 PCQGFSGMNRFNSREYSNFKNSLVASYLSFCDYYRPKYFILENVRNFVAFKKGMVLKLTL 1076
PCQGFSGMNRFNSR YS FKNSLV S+LS+CDYYRP++F+LENVRNFV+FK+ MVLKLTL
Sbjct: 1120 PCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTL 1179
Query: 1077 RALLDMGYQCTFGILQAGNYGVPQTRRRLIILAAAPGYNLPFYPEPTHVFSRRACTLTTT 1136
R L+ MGYQCTFG+LQAG YGV QTRRR IILAAAPG LP +PEP HVF+ RAC L+
Sbjct: 1180 RCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVV 1239
Query: 1137 IDGKRFSTNIHWDESAPKRTCTIQDAMSDLPQICNGANKIEIEYGSMPESHFQRLVRSND 1196
+D K+F +NI S P RT T++D MSDLP++ NGA+ +EI Y P+S FQR +R
Sbjct: 1240 VDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQ 1299
Query: 1197 ENSKLRDHICKNMAPLIQARISRIPTTPGSDWRDLPNISVTLSDGTKCKVLQYRYDDKRN 1256
LRDHICK+M+ L+ AR+ IP PGSDWRDLPNI V LSDGT + L+Y + D++N
Sbjct: 1300 YQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKN 1359
Query: 1257 GRSSSGAVRGVCACA-SGRACSPLDKQENTLIPWCLPHTGNRHNHWAGLYG 1306
GRSSSGA+RGVC+C +G+AC P +Q NTLIPWCLPHTGNRHNHWAGLYG
Sbjct: 1360 GRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYG 1410
>AF180682-1|AAF23609.1| 1280|Homo sapiens DNA
(cytosine-5)-methyltransferase protein.
Length = 1280
Score = 1029 bits (2548), Expect = 0.0
Identities = 537/1191 (45%), Positives = 720/1191 (60%), Gaps = 44/1191 (3%)
Query: 133 KCNICGQFLNNSDLIYYQGHPQDAVEEYIALTNDKL-VLSSGEDG--DIMERPQTNITGF 189
KC CGQ+L++ DL Y Q HP DAV+E LTN+KL + + E G PQ +T F
Sbjct: 16 KCIQCGQYLDDPDLKYGQ-HPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCF 74
Query: 190 TIFDEQGHLCPIDGGLVENDVRIYMSGYLKXXXXXXXXXXXXXXPVKDVGPIIEWFIHGF 249
+++ + GHLCPID GL+E ++ ++ SG K K++GPI EW+I GF
Sbjct: 75 SVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNG-KNLGPINEWWITGF 133
Query: 250 DGGDRNCITLSTEFGEYNLLKPSEAYTPLMNNLYEKIWLSKVVVEFLEEYHYLQPSYEDL 309
DGG++ I ST F EY L+ PS Y P+ + EKI++SK+VVEFL+ +YEDL
Sbjct: 134 DGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNS--DSTYEDL 191
Query: 310 LEVVRDFSIPE-LNNKKMTEEMLHKHAQFVCDQVVSLEI--EEDDEPLITLPCMRELIKL 366
+ + P LN + TE+ L +HAQFV +QV S + + D++P+ PCMR+LIKL
Sbjct: 192 INKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKL 251
Query: 367 MGIKFGKRKIRTQIQYXXXXXXXX----XXXXXXPLVRKTFESFFSNQLDKTNHE---LV 419
G+ G+R+ + + Q LV + F++FF+ Q++K + E
Sbjct: 252 AGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENA 311
Query: 420 LRRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAEDSDPDDE 479
+R+RCGVCE CQ P+CG+C AC+ M KFGG GR+K+AC R CPNMA+++A+D + D+
Sbjct: 312 FKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDD 371
Query: 480 DEYQQISEKKQDKIDDAVPVKLTGSNSKNLKWIGEPVKADATKIYYEKVEIDGAELCNGD 539
+ + S KK + K N + W+GE VK D K YY+KV ID L GD
Sbjct: 372 NIPEMPSPKKMHQ------GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGD 425
Query: 540 FVMIETSQTNIPTLVAKVVYMWKEIHNPKSGYFHGEVFIRASDTVLGEVSDPREVFLGDR 599
V + ++ P +A+V +W++ N + FH F +DTVLG SDP E+FL D
Sbjct: 426 CVSVIPDDSSKPLYLARVTALWEDSSNGQM--FHAHWFCAGTDTVLGATSDPLELFLVDE 483
Query: 600 CCHGAPLSSILRKANIERKETSADWFKLGGKEVDDEHFEDDGRTYFYSKYYDRFTSRFED 659
C LS I K + K S +W GG + + DDG+TYFY +YD+ +RFE
Sbjct: 484 C-EDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFES 542
Query: 660 LPPDPACPNALRKHRFCPSCERKTKRDARNIPKVFEKLIVKSEIVSEQNRSEWSYVKWQD 719
P P K +FC SC R + + IP+V E+L V + ++ +
Sbjct: 543 --PPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGIL---- 596
Query: 720 FDYKKGCGVFLKPGTFKLKNSMTKANTVAKPRFEKVDETIYPEYYRKNDSNTRGSNIDTG 779
Y+ G GV+L P F ++ + V +PR E VDE +YPE+YRK +GSN+D
Sbjct: 597 --YRVGDGVYLPPEAFTFNIKLS--SPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAP 652
Query: 780 EPFCVGYIAAVTAASEGPLVVPQ-DIYLKVNVLLRPENTSSKFPQ--HEDTNVLYWTTEI 836
EP+ +G I + + + DI ++VN RPENT P H D N+LYW+ E
Sbjct: 653 EPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEE 712
Query: 837 REIPFSTVVGHCHLIYEQNVPQNISLQEWLGNDPCRFYFRMAYCKSTGEFTDLPQNAISV 896
+ F V G C + Y +++P+ + + G P RFYF AY + F D P +A S
Sbjct: 713 AVVDFKAVQGRCTVEYGEDLPECVQVYSMGG--PNRFYFLEAYNAKSKSFEDPPNHARSP 770
Query: 897 XXXXXXXXXXXXXXXXXXXIETVPAKVVEEKIRPLRTLDVFAGCGGLSEGLHQAGVAECK 956
+ P +E K+ LRTLDVF+GCGGLSEG HQAG+++
Sbjct: 771 GNKGKGKGKGKGKPKSQACEPSEPE--IEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTL 828
Query: 957 WAIENVEAASHAYSLNNKSCIVFNEDCNALLKTVMSGAKHSANGLRLPMQGEVELLCGGP 1016
WAIE + A+ A+ LNN VF EDCN LLK VM+G ++ G RLP +G+VE+LCGGP
Sbjct: 829 WAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGP 888
Query: 1017 PCQGFSGMNRFNSREYSNFKNSLVASYLSFCDYYRPKYFILENVRNFVAFKKGMVLKLTL 1076
PCQGFSGMNRFNSR YS FKNSLV S+LS+CDYYRP++F+LENVRNFV+FK+ MVLKLTL
Sbjct: 889 PCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTL 948
Query: 1077 RALLDMGYQCTFGILQAGNYGVPQTRRRLIILAAAPGYNLPFYPEPTHVFSRRACTLTTT 1136
R L+ MGYQCTFG+LQAG YGV QTRRR IILAAAPG LP +PEP HVF+ RAC L+
Sbjct: 949 RCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVV 1008
Query: 1137 IDGKRFSTNIHWDESAPKRTCTIQDAMSDLPQICNGANKIEIEYGSMPESHFQRLVRSND 1196
+D K+F +NI S P RT T++D MSDLP++ NGA+ +EI Y P+S FQR +R
Sbjct: 1009 VDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQ 1068
Query: 1197 ENSKLRDHICKNMAPLIQARISRIPTTPGSDWRDLPNISVTLSDGTKCKVLQYRYDDKRN 1256
LRDHICK+M+ L+ AR+ IP PGSDWRDLPNI V LSDGT + L+Y + D++N
Sbjct: 1069 YQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKN 1128
Query: 1257 GRSSSGAVRGVCACA-SGRACSPLDKQENTLIPWCLPHTGNRHNHWAGLYG 1306
GRSSSGA+RGVC+C +G+AC P +Q NTLIPWCLPHTGNRHNHWAGLYG
Sbjct: 1129 GRSSSGALRGVCSCVEAGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYG 1179
>AB209413-1|BAD92650.1| 1606|Homo sapiens DNA
(cytosine-5-)-methyltransferase 1 variant protein.
Length = 1606
Score = 1028 bits (2546), Expect = 0.0
Identities = 538/1194 (45%), Positives = 721/1194 (60%), Gaps = 47/1194 (3%)
Query: 133 KCNICGQFLNNSDLIYYQGHPQDAVEEYIALTNDKL-VLSSGEDG--DIMERPQTNITGF 189
KC CGQ+L++ DL Y Q HP DAV+E LTN+KL + + E G PQ +T F
Sbjct: 339 KCIQCGQYLDDPDLKYGQ-HPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCF 397
Query: 190 TIFDEQGHLCPIDGGLVENDVRIYMSGYLKXXXXXXXXXXXXXXPVKDVGPIIEWFIHGF 249
+++ + GHLCPID GL+E ++ ++ SG K K++GPI EW+I GF
Sbjct: 398 SVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNG-KNLGPINEWWITGF 456
Query: 250 DGGDRNCITLSTEFGEYNLLKPSEAYTPLMNNLYEKIWLSKVVVEFLEEYHYLQPSYEDL 309
DGG++ I ST F EY L+ PS Y P+ + EKI++SK+VVEFL+ +YEDL
Sbjct: 457 DGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNS--DSTYEDL 514
Query: 310 LEVVRDFSIPE-LNNKKMTEEMLHKHAQFVCDQVVSLEI--EEDDEPLITLPCMRELIKL 366
+ + P LN + TE+ L +HAQFV +QV S + + D++P+ PCMR+LIKL
Sbjct: 515 INKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKL 574
Query: 367 MGIKFGKRKIRTQIQYXXXXXXXX----XXXXXXPLVRKTFESFFSNQLDKTNHE---LV 419
G+ G+R+ + + Q LV + F++FF+ Q++K + E
Sbjct: 575 AGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENA 634
Query: 420 LRRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAEDSDPDDE 479
+R+RCGVCE CQ P+CG+C AC+ M KFGG GR+K+AC R CPNMA+++A+D + D+
Sbjct: 635 FKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDD 694
Query: 480 DEYQQISEKKQDKIDDAVPVKLTGSNSKNLKWIGEPVKADATKIYYEKVEIDGAELCNGD 539
+ + S KK + K N + W+GE VK D K YY+KV ID L GD
Sbjct: 695 NIPEMPSPKKMHQ------GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGD 748
Query: 540 FVMIETSQTNIPTLVAKVVYMWKEIHNPKSGYFHGEVFIRASDTVLGEVSDPREVFLGDR 599
V + ++ P +A+V +W++ N + FH F +DTVLG SDP E+FL D
Sbjct: 749 CVSVIPDDSSKPLYLARVTALWEDSSNGQM--FHAHWFCAGTDTVLGATSDPLELFLVDE 806
Query: 600 CCHGAPLSSILRKANIERKETSADWFKLGGKEVDDEHFEDDGRTYFYSKYYDRFTSRFED 659
C LS I K + K S +W GG + + DDG+TYFY +YD+ +RFE
Sbjct: 807 C-EDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFES 865
Query: 660 LPPDPACPNALRKHRFCPSCERKTKRDARNIPKVFEKLIVKSEIVSEQNRSEWSYVKWQD 719
P P K +FC SC R + + IP+V E+L V + ++ +
Sbjct: 866 --PPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGIL---- 919
Query: 720 FDYKKGCGVFLKPGTFKLKNSMTKANTVAKPRFEKVDETIYPEYYRKNDSNTRGSNIDTG 779
Y+ G GV+L P F ++ + V +PR E VDE +YPE+YRK +GSN+D
Sbjct: 920 --YRVGDGVYLPPEAFTFNIKLS--SPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAP 975
Query: 780 EPFCVGYIAAVTAASEGPLVVPQ-DIYLKVNVLLRPENTSSKFPQ--HEDTNVLYWTTEI 836
EP+ +G I + + + DI ++VN RPENT P H D N+LYW+ E
Sbjct: 976 EPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEE 1035
Query: 837 REIPFSTVVGHCHLIYEQNVPQNISLQEWLGNDPCRFYFRMAYCKSTGEFTDLPQNAISV 896
+ F V G C + Y +++P+ + + G P RFYF AY + F D P +A S
Sbjct: 1036 AVVDFKAVQGRCTVEYGEDLPECVQVYSMGG--PNRFYFLEAYNAKSKSFEDPPNHARSP 1093
Query: 897 XXXXXXXXXXXXXXXXXXXIETVPAKVVEEKIRPLRTLDVFAGCGGLSEGLHQAGVAECK 956
+ P +E K+ LRTLDVF+GCGGLSEG HQAG+++
Sbjct: 1094 GNKGKGKGKGKGKPKSQACEPSEPE--IEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTL 1151
Query: 957 WAIENVEAASHAYSLNNKSCIVFNEDCNALLKTVMSGAKHSANGLRLPMQGEVELLCGGP 1016
WAIE + A+ A+ LNN VF EDCN LLK VM+G ++ G RLP +G+VE+LCGGP
Sbjct: 1152 WAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGP 1211
Query: 1017 PCQGFSGMNRFNSREYSNFKNSLVASYLSFCDYYRPKYFILENVRNFVAFKKGMVLKLTL 1076
PCQGFSGMNRFNSR YS FKNSLV S+LS+CDYYRP++F+LENVRNFV+FK+ MVLKLTL
Sbjct: 1212 PCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTL 1271
Query: 1077 RALLDMGYQCTFGILQAGNYGVPQTRRRLIILAAAPGYNLPFYPEPTHVFSRRACTLTTT 1136
R L+ MGYQCTFG+LQAG YGV QTRRR IILAAAPG LP +PEP HVF+ RAC L+
Sbjct: 1272 RCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVV 1331
Query: 1137 IDGKRFSTNIHWDESAPKRTCTIQDAMSDLPQICNGANKIEIEYGSMPESHFQRLVRSND 1196
+D K+F +NI S P RT T++D MSDLP++ NGA+ +EI Y P+S FQR +R
Sbjct: 1332 VDDKKFVSNITRLSSGPFRTITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQ 1391
Query: 1197 ENSKLRDHICKNMAPLIQARISRIPTTPGSDWRDLPNISVTLSDGTKCKVLQYRYDDKRN 1256
LRDHICK+M+ L+ AR+ IP PGSDWRDLPNI V LSDGT + L+Y + D++N
Sbjct: 1392 YQPILRDHICKDMSALVAARMRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKN 1451
Query: 1257 GRSSSGAVRGVCAC----ASGRACSPLDKQENTLIPWCLPHTGNRHNHWAGLYG 1306
GRSSSGA+RGVC+C +SG+AC P +Q NTLIPWCLPHTGNRHNHWAGLYG
Sbjct: 1452 GRSSSGALRGVCSCVEGGSSGKACDPAARQFNTLIPWCLPHTGNRHNHWAGLYG 1505
>AC010077-1|AAD54507.1| 966|Homo sapiens MTDM_HUMAN [AA 1- 966]
protein.
Length = 966
Score = 487 bits (1201), Expect = e-136
Identities = 282/759 (37%), Positives = 410/759 (54%), Gaps = 41/759 (5%)
Query: 133 KCNICGQFLNNSDLIYYQGHPQDAVEEYIALTNDKL-VLSSGEDG--DIMERPQTNITGF 189
KC CGQ+L++ DL Y Q HP DAV+E LTN+KL + + E G PQ +T F
Sbjct: 231 KCIQCGQYLDDPDLKYGQ-HPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTCF 289
Query: 190 TIFDEQGHLCPIDGGLVENDVRIYMSGYLKXXXXXXXXXXXXXXPVKDVGPIIEWFIHGF 249
+++ + GHLCPID GL+E ++ ++ SG K K++GPI EW+I GF
Sbjct: 290 SVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNG-KNLGPINEWWITGF 348
Query: 250 DGGDRNCITLSTEFGEYNLLKPSEAYTPLMNNLYEKIWLSKVVVEFLEEYHYLQPSYEDL 309
DGG++ I ST F EY L+ PS Y P+ + EKI++SK+VVEFL+ +YEDL
Sbjct: 349 DGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNS--DSTYEDL 406
Query: 310 LEVVRDFSIPE-LNNKKMTEEMLHKHAQFVCDQVVSLEI--EEDDEPLITLPCMRELIKL 366
+ + P LN + TE+ L +HAQFV +QV S + + D++P+ PCMR+LIKL
Sbjct: 407 INKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKL 466
Query: 367 MGIKFGKRKIRTQIQYXXXXXXXX----XXXXXXPLVRKTFESFFSNQLDKTNHE---LV 419
G+ G+R+ + + Q LV + F++FF+ Q++K + E
Sbjct: 467 AGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDKENA 526
Query: 420 LRRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAEDSDPDDE 479
+R+RCGVCE CQ P+CG+C AC+ M KFGG GR+K+AC R CPNMA+++A+D + D+
Sbjct: 527 FKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEEVDD 586
Query: 480 DEYQQISEKKQDKIDDAVPVKLTGSNSKNLKWIGEPVKADATKIYYEKVEIDGAELCNGD 539
+ + S KK + K N + W+GE VK D K YY+KV ID L GD
Sbjct: 587 NIPEMPSPKKMHQ------GKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGD 640
Query: 540 FVMIETSQTNIPTLVAKVVYMWKEIHNPKSGYFHGEVFIRASDTVLGEVSDPREVFLGDR 599
V + ++ P +A+V +W++ N + FH F +DTVLG SDP E+FL D
Sbjct: 641 CVSVIPDDSSKPLYLARVTALWEDSSNGQ--MFHAHWFCAGTDTVLGATSDPLELFLVDE 698
Query: 600 CCHGAPLSSILRKANIERKETSADWFKLGGKEVDDEHFEDDGRTYFYSKYYDRFTSRFED 659
C LS I K + K S +W GG + + DDG+TYFY +YD+ +RFE
Sbjct: 699 -CEDMQLSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFES 757
Query: 660 LPPDPACPNALRKHRFCPSCERKTKRDARNIPKVFEKLIVKSEIVSEQNRSEWSYVKWQD 719
P P K +FC SC R + + IP+V E+L V + ++ +
Sbjct: 758 --PPKTQPTEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGIL---- 811
Query: 720 FDYKKGCGVFLKPGTFKLKNSMTKANTVAKPRFEKVDETIYPEYYRKNDSNTRGSNIDTG 779
Y+ G GV+L P F ++ ++ V +PR E VDE +YPE+YRK +GSN+D
Sbjct: 812 --YRVGDGVYLPPEAFTF--NIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAP 867
Query: 780 EPFCVGYIAAVTAASE-GPLVVPQDIYLKVNVLLRPENTSSKFP--QHEDTNVLYWTTEI 836
EP+ +G I + + DI ++VN RPENT P H D N+LYW+ E
Sbjct: 868 EPYRIGRIKEIFCPKKSNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEE 927
Query: 837 REIPFSTVVGHCHLIYEQNVPQNISLQEWLGNDPCRFYF 875
+ F V G C + Y +++P+ + + G P RFYF
Sbjct: 928 AVVDFKAVQGRCTVEYGEDLPECVQVYSMGG--PNRFYF 964
>BC115379-1|AAI15380.1| 559|Homo sapiens FBXL10 protein protein.
Length = 559
Score = 63.3 bits (147), Expect = 6e-09
Identities = 26/56 (46%), Positives = 34/56 (60%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAEDSDP 476
RR RC CEAC +CGEC+ C+ M KFGG GR K++C+ R C A+ + P
Sbjct: 492 RRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQCIATAIRSLISACP 547
>BC115380-1|AAI15381.1| 706|Homo sapiens FBXL10 protein protein.
Length = 706
Score = 62.5 bits (145), Expect = 1e-08
Identities = 24/43 (55%), Positives = 30/43 (69%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLC 463
RR RC CEAC +CGEC+ C+ M KFGG GR K++C+ R C
Sbjct: 609 RRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQC 651
>AJ459424-1|CAD30700.1| 1336|Homo sapiens JEMMA protein protein.
Length = 1336
Score = 62.5 bits (145), Expect = 1e-08
Identities = 24/43 (55%), Positives = 30/43 (69%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLC 463
RR RC CEAC +CGEC+ C+ M KFGG GR K++C+ R C
Sbjct: 609 RRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQC 651
>AB031230-1|BAA97672.1| 827|Homo sapiens protein containing CXXC
domain 2 protein.
Length = 827
Score = 62.5 bits (145), Expect = 1e-08
Identities = 24/43 (55%), Positives = 30/43 (69%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLC 463
RR RC CEAC +CGEC+ C+ M KFGG GR K++C+ R C
Sbjct: 130 RRTRCRKCEACLRTECGECHFCKDMKKFGGPGRMKQSCIMRQC 172
>BC064360-1|AAH64360.1| 1162|Homo sapiens F-box and leucine-rich
repeat protein 11 protein.
Length = 1162
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 4/72 (5%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLC--PNM--AVEQAEDSDP 476
RR RC C+AC +CG C+ CR M KFGG GR K++CV R C P + +V + +
Sbjct: 567 RRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV 626
Query: 477 DDEDEYQQISEK 488
D +E Q +K
Sbjct: 627 DQNEETQDFEKK 638
>BC047486-1|AAH47486.1| 782|Homo sapiens FBXL11 protein protein.
Length = 782
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 4/72 (5%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLC--PNM--AVEQAEDSDP 476
RR RC C+AC +CG C+ CR M KFGG GR K++CV R C P + +V + +
Sbjct: 567 RRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV 626
Query: 477 DDEDEYQQISEK 488
D +E Q +K
Sbjct: 627 DQNEETQDFEKK 638
>BC047371-1|AAH47371.1| 856|Homo sapiens FBXL11 protein protein.
Length = 856
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 4/72 (5%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLC--PNM--AVEQAEDSDP 476
RR RC C+AC +CG C+ CR M KFGG GR K++CV R C P + +V + +
Sbjct: 261 RRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV 320
Query: 477 DDEDEYQQISEK 488
D +E Q +K
Sbjct: 321 DQNEETQDFEKK 332
>AK024505-1|BAB15795.1| 757|Homo sapiens FLJ00115 protein protein.
Length = 757
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 4/72 (5%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLC--PNM--AVEQAEDSDP 476
RR RC C+AC +CG C+ CR M KFGG GR K++CV R C P + +V + +
Sbjct: 162 RRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV 221
Query: 477 DDEDEYQQISEK 488
D +E Q +K
Sbjct: 222 DQNEETQDFEKK 233
>AB023221-1|BAA76848.2| 1163|Homo sapiens KIAA1004 protein protein.
Length = 1163
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/72 (41%), Positives = 41/72 (56%), Gaps = 4/72 (5%)
Query: 421 RRKRCGVCEACQLPDCGECNACRAMAKFGGHGRTKKACVRRLC--PNM--AVEQAEDSDP 476
RR RC C+AC +CG C+ CR M KFGG GR K++CV R C P + +V + +
Sbjct: 568 RRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV 627
Query: 477 DDEDEYQQISEK 488
D +E Q +K
Sbjct: 628 DQNEETQDFEKK 639
>Z69744-1|CAA93625.1| 4005|Homo sapiens ALL-1 protein protein.
Length = 4005
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 421 RRKRCGVCEACQLP-DCGECNACRAMAKFGGHGRTKKACVRRLC------PNMAVEQAED 473
R +RCG C CQ+P DCG C C KFGG K+ C R C P+ A Q +
Sbjct: 1184 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1243
Query: 474 SDPDDEDEYQQISEKKQDKIDDAVPVKLTGSNSK 507
+++ + SEKK K + +V + S+ K
Sbjct: 1244 KAVKKKEKKSKTSEKKDSK-ESSVVKNVVDSSQK 1276
>L22179-1|AAC37520.1| 2311|Homo sapiens MLL-AF4 der(11) fusion protein
protein.
Length = 2311
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 421 RRKRCGVCEACQLP-DCGECNACRAMAKFGGHGRTKKACVRRLC------PNMAVEQAED 473
R +RCG C CQ+P DCG C C KFGG K+ C R C P+ A Q +
Sbjct: 1192 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1251
Query: 474 SDPDDEDEYQQISEKKQDKIDDAVPVKLTGSNSK 507
+++ + SEKK K + +V + S+ K
Sbjct: 1252 KAVKKKEKKSKTSEKKDSK-ESSVVKNVVDSSQK 1284
>L04284-1|AAA58669.1| 3969|Homo sapiens HRX protein.
Length = 3969
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 421 RRKRCGVCEACQLP-DCGECNACRAMAKFGGHGRTKKACVRRLC------PNMAVEQAED 473
R +RCG C CQ+P DCG C C KFGG K+ C R C P+ A Q +
Sbjct: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210
Query: 474 SDPDDEDEYQQISEKKQDKIDDAVPVKLTGSNSK 507
+++ + SEKK K + +V + S+ K
Sbjct: 1211 KAVKKKEKKSKTSEKKDSK-ESSVVKNVVDSSQK 1243
>D14540-1|BAA03407.1| 1909|Homo sapiens MLL protein.
Length = 1909
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 421 RRKRCGVCEACQLP-DCGECNACRAMAKFGGHGRTKKACVRRLC------PNMAVEQAED 473
R +RCG C CQ+P DCG C C KFGG K+ C R C P+ A Q +
Sbjct: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210
Query: 474 SDPDDEDEYQQISEKKQDKIDDAVPVKLTGSNSK 507
+++ + SEKK K + +V + S+ K
Sbjct: 1211 KAVKKKEKKSKTSEKKDSK-ESSVVKNVVDSSQK 1243
>AY373585-1|AAQ63624.1| 3969|Homo sapiens myeloid/lymphoid or
mixed-lineage leukemia (trithorax homolog, Drosophila)
protein.
Length = 3969
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 421 RRKRCGVCEACQLP-DCGECNACRAMAKFGGHGRTKKACVRRLC------PNMAVEQAED 473
R +RCG C CQ+P DCG C C KFGG K+ C R C P+ A Q +
Sbjct: 1151 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 1210
Query: 474 SDPDDEDEYQQISEKKQDKIDDAVPVKLTGSNSK 507
+++ + SEKK K + +V + S+ K
Sbjct: 1211 KAVKKKEKKSKTSEKKDSK-ESSVVKNVVDSSQK 1243
>AB209508-1|BAD92745.1| 2880|Homo sapiens myeloid/lymphoid or
mixed-lineage leukemia (trithorax homolog, Drosophila)
vari protein.
Length = 2880
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/94 (34%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 421 RRKRCGVCEACQLP-DCGECNACRAMAKFGGHGRTKKACVRRLC------PNMAVEQAED 473
R +RCG C CQ+P DCG C C KFGG K+ C R C P+ A Q +
Sbjct: 62 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQA 121
Query: 474 SDPDDEDEYQQISEKKQDKIDDAVPVKLTGSNSK 507
+++ + SEKK K + +V + S+ K
Sbjct: 122 KAVKKKEKKSKTSEKKDSK-ESSVVKNVVDSSQK 154
>AF272382-1|AAG31986.1| 316|Homo sapiens MLL protein protein.
Length = 316
Score = 53.2 bits (122), Expect = 6e-06
Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 1/47 (2%)
Query: 421 RRKRCGVCEACQLP-DCGECNACRAMAKFGGHGRTKKACVRRLCPNM 466
R +RCG C CQ+P DCG C C KFGG K+ C R C N+
Sbjct: 237 RSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNL 283
>AF045888-1|AAC39764.1| 391|Homo sapiens putative DNA cytosine
methyltransferase DNMT2 protein.
Length = 391
Score = 50.8 bits (116), Expect = 3e-05
Identities = 50/197 (25%), Positives = 83/197 (42%), Gaps = 27/197 (13%)
Query: 928 IRPLRTLDVFAGCGGLSEGLHQAGV-AECKWAIENVEAASHAYSLNNKSCIVFNEDCNAL 986
+ PLR L++++G GG+ L ++ + A+ AI+ A+ Y N L
Sbjct: 1 MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHT-------QLL 53
Query: 987 LKTVMSGAKHSANGLRLPMQGEVELLCGGPPCQGFSGMNRFNSREYSNFKNSLVASYLSF 1046
KT+ + L M + PPCQ F+ + R + +S S+L
Sbjct: 54 AKTIEGITLEEFDRLSFDM------ILMSPPCQPFTRIGR-----QGDMTDSRTNSFLHI 102
Query: 1047 CDYYR-----PKYFILENVRNFVAFKKGMVLKLTLRALLDMGYQCTFGILQAGNYGVPQT 1101
D PKY +LENV+ F + L ++ + + G+Q IL + G+P +
Sbjct: 103 LDILPRLQKLPKYILLENVKGF---EVSSTRDLLIQTIENCGFQYQEFILSPTSLGIPNS 159
Query: 1102 RRRLIILAAAPGYNLPF 1118
R R ++A LPF
Sbjct: 160 RLRYFLIAKLQSEPLPF 176
>BC047733-1|AAH47733.1| 391|Homo sapiens tRNA aspartic acid
methyltransferase 1 protein.
Length = 391
Score = 50.4 bits (115), Expect = 4e-05
Identities = 47/192 (24%), Positives = 80/192 (41%), Gaps = 17/192 (8%)
Query: 928 IRPLRTLDVFAGCGGLSEGLHQAGV-AECKWAIENVEAASHAYSLNNKSCIVFNEDCNAL 986
+ PLR L++++G GG+ L ++ + A+ AI+ A+ Y N L
Sbjct: 1 MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHT-------QLL 53
Query: 987 LKTVMSGAKHSANGLRLPMQGEVELLCGGPPCQGFSGMNRFNSREYSNFKNSLVASYLSF 1046
KT+ + L M + PPCQ F+ + R S + L +
Sbjct: 54 AKTIEGITLEEFDRLSFDM------ILMSPPCQPFTRIGRQGDMTDSRTNSFLYILDILP 107
Query: 1047 CDYYRPKYFILENVRNFVAFKKGMVLKLTLRALLDMGYQCTFGILQAGNYGVPQTRRRLI 1106
PKY +LENV+ F + L ++ + + G+Q +L + G+P +R R
Sbjct: 108 RLQKLPKYILLENVKGF---EVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYF 164
Query: 1107 ILAAAPGYNLPF 1118
++A LPF
Sbjct: 165 LIAKLQSEPLPF 176
>BC015733-1|AAH15733.1| 660|Homo sapiens CXXC1 protein protein.
Length = 660
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 423 KRCGVCEACQ-LPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVE 469
+ CG CEAC+ DCG C+ CR M KFGG + ++ C R C A E
Sbjct: 167 RMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE 214
>BC014940-1|AAH14940.1| 656|Homo sapiens CXXC finger 1 (PHD domain)
protein.
Length = 656
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 423 KRCGVCEACQ-LPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVE 469
+ CG CEAC+ DCG C+ CR M KFGG + ++ C R C A E
Sbjct: 167 RMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE 214
>AF149758-1|AAF37799.1| 656|Homo sapiens CpG binding protein
protein.
Length = 656
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 423 KRCGVCEACQ-LPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVE 469
+ CG CEAC+ DCG C+ CR M KFGG + ++ C R C A E
Sbjct: 167 RMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE 214
>AB209883-1|BAD93120.1| 523|Homo sapiens CpG binding protein
variant protein.
Length = 523
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 423 KRCGVCEACQ-LPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVE 469
+ CG CEAC+ DCG C+ CR M KFGG + ++ C R C A E
Sbjct: 34 RMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE 81
>AB031069-1|BAA96307.1| 656|Homo sapiens protein containing CXXC
domain 1 protein.
Length = 656
Score = 50.4 bits (115), Expect = 4e-05
Identities = 22/48 (45%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Query: 423 KRCGVCEACQ-LPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVE 469
+ CG CEAC+ DCG C+ CR M KFGG + ++ C R C A E
Sbjct: 167 RMCGECEACRRTEDCGHCDFCRDMKKFGGPNKIRQKCRLRQCQLRARE 214
>CR450316-1|CAG29312.1| 391|Homo sapiens DNMT2 protein.
Length = 391
Score = 50.0 bits (114), Expect = 6e-05
Identities = 49/197 (24%), Positives = 83/197 (42%), Gaps = 27/197 (13%)
Query: 928 IRPLRTLDVFAGCGGLSEGLHQAGV-AECKWAIENVEAASHAYSLNNKSCIVFNEDCNAL 986
+ PLR L++++G GG+ L ++ + A+ AI+ A+ Y N L
Sbjct: 1 MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHT-------QLL 53
Query: 987 LKTVMSGAKHSANGLRLPMQGEVELLCGGPPCQGFSGMNRFNSREYSNFKNSLVASYLSF 1046
KT+ + L M + PPCQ F+ + R + +S S+L
Sbjct: 54 AKTIEGITLEEFDRLSFDM------ILMSPPCQPFTRIGR-----QGDMTDSRTNSFLHI 102
Query: 1047 CDYYR-----PKYFILENVRNFVAFKKGMVLKLTLRALLDMGYQCTFGILQAGNYGVPQT 1101
D PKY +LENV+ F + L ++ + + G+Q +L + G+P +
Sbjct: 103 LDILPRLQKLPKYILLENVKGF---EVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNS 159
Query: 1102 RRRLIILAAAPGYNLPF 1118
R R ++A LPF
Sbjct: 160 RLRYFLIAKLQSEPLPF 176
>AL133415-5|CAB87964.1| 391|Homo sapiens DNA
(cytosine-5-)-methyltransferase 2 protein.
Length = 391
Score = 50.0 bits (114), Expect = 6e-05
Identities = 49/197 (24%), Positives = 83/197 (42%), Gaps = 27/197 (13%)
Query: 928 IRPLRTLDVFAGCGGLSEGLHQAGV-AECKWAIENVEAASHAYSLNNKSCIVFNEDCNAL 986
+ PLR L++++G GG+ L ++ + A+ AI+ A+ Y N L
Sbjct: 1 MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHT-------QLL 53
Query: 987 LKTVMSGAKHSANGLRLPMQGEVELLCGGPPCQGFSGMNRFNSREYSNFKNSLVASYLSF 1046
KT+ + L M + PPCQ F+ + R + +S S+L
Sbjct: 54 AKTIEGITLEEFDRLSFDM------ILMSPPCQPFTRIGR-----QGDMTDSRTNSFLHI 102
Query: 1047 CDYYR-----PKYFILENVRNFVAFKKGMVLKLTLRALLDMGYQCTFGILQAGNYGVPQT 1101
D PKY +LENV+ F + L ++ + + G+Q +L + G+P +
Sbjct: 103 LDILPRLQKLPKYILLENVKGF---EVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNS 159
Query: 1102 RRRLIILAAAPGYNLPF 1118
R R ++A LPF
Sbjct: 160 RLRYFLIAKLQSEPLPF 176
>AJ223333-1|CAA11272.1| 391|Homo sapiens DNA methyltransferase
protein.
Length = 391
Score = 50.0 bits (114), Expect = 6e-05
Identities = 49/197 (24%), Positives = 83/197 (42%), Gaps = 27/197 (13%)
Query: 928 IRPLRTLDVFAGCGGLSEGLHQAGV-AECKWAIENVEAASHAYSLNNKSCIVFNEDCNAL 986
+ PLR L++++G GG+ L ++ + A+ AI+ A+ Y N L
Sbjct: 1 MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHT-------QLL 53
Query: 987 LKTVMSGAKHSANGLRLPMQGEVELLCGGPPCQGFSGMNRFNSREYSNFKNSLVASYLSF 1046
KT+ + L M + PPCQ F+ + R + +S S+L
Sbjct: 54 AKTIEGITLEEFDRLSFDM------ILMSPPCQPFTRIGR-----QGDMTDSRTNSFLHI 102
Query: 1047 CDYYR-----PKYFILENVRNFVAFKKGMVLKLTLRALLDMGYQCTFGILQAGNYGVPQT 1101
D PKY +LENV+ F + L ++ + + G+Q +L + G+P +
Sbjct: 103 LDILPRLQKLPKYILLENVKGF---EVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNS 159
Query: 1102 RRRLIILAAAPGYNLPF 1118
R R ++A LPF
Sbjct: 160 RLRYFLIAKLQSEPLPF 176
>AJ007041-1|CAB45385.1| 2715|Homo sapiens trithorax homologue 2
protein.
Length = 2715
Score = 50.0 bits (114), Expect = 6e-05
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 414 TNHELVLRRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAE 472
++H +R RCG C C ++ DCG C C KFGG K+ CV R C + + E
Sbjct: 955 SHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKME 1014
>AF186605-1|AAD56420.1| 2605|Homo sapiens MLL2 protein protein.
Length = 2605
Score = 50.0 bits (114), Expect = 6e-05
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 414 TNHELVLRRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAE 472
++H +R RCG C C ++ DCG C C KFGG K+ CV R C + + E
Sbjct: 845 SHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKME 904
>AF104918-1|AAD17932.1| 1010|Homo sapiens myeloid/lymphoid leukemia
2 protein.
Length = 1010
Score = 50.0 bits (114), Expect = 6e-05
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 414 TNHELVLRRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAE 472
++H +R RCG C C ++ DCG C C KFGG K+ CV R C + + E
Sbjct: 293 SHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKME 352
>AF012128-1|AAC51939.1| 391|Homo sapiens putative DNA
methyltransferase protein.
Length = 391
Score = 50.0 bits (114), Expect = 6e-05
Identities = 49/197 (24%), Positives = 83/197 (42%), Gaps = 27/197 (13%)
Query: 928 IRPLRTLDVFAGCGGLSEGLHQAGV-AECKWAIENVEAASHAYSLNNKSCIVFNEDCNAL 986
+ PLR L++++G GG+ L ++ + A+ AI+ A+ Y N L
Sbjct: 1 MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHT-------QLL 53
Query: 987 LKTVMSGAKHSANGLRLPMQGEVELLCGGPPCQGFSGMNRFNSREYSNFKNSLVASYLSF 1046
KT+ + L M + PPCQ F+ + R + +S S+L
Sbjct: 54 AKTIEGITLEEFDRLSFDM------ILMSPPCQPFTRIGR-----QGDMTDSRTNSFLHI 102
Query: 1047 CDYYR-----PKYFILENVRNFVAFKKGMVLKLTLRALLDMGYQCTFGILQAGNYGVPQT 1101
D PKY +LENV+ F + L ++ + + G+Q +L + G+P +
Sbjct: 103 LDILPRLQKLPKYILLENVKGF---EVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNS 159
Query: 1102 RRRLIILAAAPGYNLPF 1118
R R ++A LPF
Sbjct: 160 RLRYFLIAKLQSEPLPF 176
>AB002302-1|BAA20763.3| 2415|Homo sapiens KIAA0304 protein protein.
Length = 2415
Score = 50.0 bits (114), Expect = 6e-05
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Query: 414 TNHELVLRRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQAE 472
++H +R RCG C C ++ DCG C C KFGG K+ CV R C + + E
Sbjct: 655 SHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKME 714
>EF488685-1|ABP02056.1| 536|Homo sapiens methyl-CpG binding domain
protein 1 variant 8 protein.
Length = 536
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQ 470
+ ++CG C AC + DCG C+ C KFGG + ++ C R C A+++
Sbjct: 311 QNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKR 361
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 418 LVLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+V R + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 218 IVERSRGCGVCRGCQTQEDCGRCPICLRPPRPGLRRQWK--CVQRRC 262
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 170 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
>AJ564845-1|CAD92308.1| 550|Homo sapiens methyl-CpG binding domain
protein 1, splice form 6 protein.
Length = 550
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQ 470
+ ++CG C AC + DCG C+ C KFGG + ++ C R C A+++
Sbjct: 334 QNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKR 384
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 418 LVLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+V R + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 218 IVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 262
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 170 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
>AF120981-1|AAD50371.1| 605|Homo sapiens methyl-CpG binding protein
1 protein.
Length = 605
Score = 44.8 bits (101), Expect = 0.002
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQ 470
+ ++CG C AC + DCG C+ C KFGG + ++ C R C A+++
Sbjct: 334 QNRKCGACAACLRRMDCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKR 384
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 418 LVLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+V R + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 218 IVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 262
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 170 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
>Y10746-1|CAA71735.1| 556|Homo sapiens methyl-CpG binding protein
protein.
Length = 556
Score = 41.9 bits (94), Expect = 0.015
Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQ 470
+ ++CG C AC + CG C+ C KFGG + ++ C R C A+++
Sbjct: 285 QNRKCGACAACLRRNGCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKR 335
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ + + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 170 MFKSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 213
>AF078831-1|AAD51443.1| 586|Homo sapiens methyl-CpG binding protein
splice variant 2 protein.
Length = 586
Score = 41.9 bits (94), Expect = 0.015
Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQ 470
+ ++CG C AC + CG C+ C KFGG + ++ C R C A+++
Sbjct: 311 QNRKCGACAACLRRNGCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKR 361
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 418 LVLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+V R + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 218 IVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 262
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 170 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
>AF078830-1|AAD51442.1| 605|Homo sapiens methyl-CpG binding protein
splice variant 1 protein.
Length = 605
Score = 41.9 bits (94), Expect = 0.015
Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACRAMAKFGGHGRTKKACVRRLCPNMAVEQ 470
+ ++CG C AC + CG C+ C KFGG + ++ C R C A+++
Sbjct: 334 QNRKCGACAACLRRNGCGRCDFCCDKPKFGGSNQKRQKCRWRQCLQFAMKR 384
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 418 LVLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+V R + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 218 IVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 262
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 170 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
>AL713888-4|CAI15118.1| 2136|Homo sapiens leukemia-associated
protein with a CXXC domain protein.
Length = 2136
Score = 39.5 bits (88), Expect = 0.078
Identities = 15/24 (62%), Positives = 18/24 (75%), Gaps = 1/24 (4%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACR 443
+RKRCGVCE C Q +CGEC C+
Sbjct: 587 KRKRCGVCEPCQQKTNCGECTYCK 610
>AL513534-3|CAH70220.1| 2136|Homo sapiens leukemia-associated
protein with a CXXC domain protein.
Length = 2136
Score = 39.5 bits (88), Expect = 0.078
Identities = 15/24 (62%), Positives = 18/24 (75%), Gaps = 1/24 (4%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACR 443
+RKRCGVCE C Q +CGEC C+
Sbjct: 587 KRKRCGVCEPCQQKTNCGECTYCK 610
>AF430147-1|AAM88301.1| 2136|Homo sapiens leukemia-associated
protein with a CXXC domain protein.
Length = 2136
Score = 39.5 bits (88), Expect = 0.078
Identities = 15/24 (62%), Positives = 18/24 (75%), Gaps = 1/24 (4%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACR 443
+RKRCGVCE C Q +CGEC C+
Sbjct: 587 KRKRCGVCEPCQQKTNCGECTYCK 610
>AL133415-4|CAI39483.1| 134|Homo sapiens DNA
(cytosine-5-)-methyltransferase 2 protein.
Length = 134
Score = 37.5 bits (83), Expect = 0.32
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 1052 PKYFILENVRNFVAFKKGMVLKLTLRALLDMGYQCTFGILQAGNYGVPQTRRRLIILAAA 1111
PKY +LENV+ F + L ++ + + G+Q +L + G+P +R R ++A
Sbjct: 68 PKYILLENVKGF---EVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKL 124
Query: 1112 PGYNLPF 1118
LPF
Sbjct: 125 QSEPLPF 131
>AF329940-1|AAK68034.1| 137|Homo sapiens DNA methyltransferase 2b
protein.
Length = 137
Score = 37.5 bits (83), Expect = 0.32
Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Query: 1052 PKYFILENVRNFVAFKKGMVLKLTLRALLDMGYQCTFGILQAGNYGVPQTRRRLIILAAA 1111
PKY +LENV+ F + L ++ + + G+Q +L + G+P +R R ++A
Sbjct: 71 PKYILLENVKGF---EVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKL 127
Query: 1112 PGYNLPF 1118
LPF
Sbjct: 128 QSEPLPF 134
>BC119752-1|AAI19753.1| 198|Homo sapiens CXXC finger 4 protein.
Length = 198
Score = 36.7 bits (81), Expect = 0.55
Identities = 14/24 (58%), Positives = 19/24 (79%), Gaps = 1/24 (4%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACR 443
+RKRCGVC C +L +CG C++CR
Sbjct: 135 KRKRCGVCVPCKRLINCGVCSSCR 158
>BC119751-1|AAI19752.1| 198|Homo sapiens CXXC finger 4 protein.
Length = 198
Score = 36.7 bits (81), Expect = 0.55
Identities = 14/24 (58%), Positives = 19/24 (79%), Gaps = 1/24 (4%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACR 443
+RKRCGVC C +L +CG C++CR
Sbjct: 135 KRKRCGVCVPCKRLINCGVCSSCR 158
>BC033242-1|AAH33242.1| 549|Homo sapiens methyl-CpG binding domain
protein 1 protein.
Length = 549
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 418 LVLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+V R + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 218 IVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 262
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 170 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
>AF272159-1|AAG42072.1| 198|Homo sapiens Dvl-binding protein IDAX
protein.
Length = 198
Score = 36.7 bits (81), Expect = 0.55
Identities = 14/24 (58%), Positives = 19/24 (79%), Gaps = 1/24 (4%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACR 443
+RKRCGVC C +L +CG C++CR
Sbjct: 135 KRKRCGVCVPCKRLINCGVCSSCR 158
>AF078833-1|AAD51445.1| 503|Homo sapiens methyl-CpG binding protein
splice variant 4 protein.
Length = 503
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 418 LVLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+V R + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 218 IVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 262
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 170 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
>AF078832-1|AAD51444.1| 549|Homo sapiens methyl-CpG binding protein
splice variant 3 protein.
Length = 549
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 418 LVLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+V R + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 218 IVERSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 262
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 170 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 215
>AC093628-1|AAY40933.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 36.7 bits (81), Expect = 0.55
Identities = 14/24 (58%), Positives = 19/24 (79%), Gaps = 1/24 (4%)
Query: 421 RRKRCGVCEAC-QLPDCGECNACR 443
+RKRCGVC C +L +CG C++CR
Sbjct: 135 KRKRCGVCVPCKRLINCGVCSSCR 158
>AB209765-1|BAD93002.1| 397|Homo sapiens methyl-CpG binding domain
protein 1 isoform PCM1 variant protein.
Length = 397
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 3/46 (6%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ + + CGVC CQ DCG C C + G + K CV+R C
Sbjct: 94 MFKSRGCGVCRGCQTQEDCGHCPICLRPPRPGLRRQWK--CVQRRC 137
>AF072241-1|AAC68870.1| 52|Homo sapiens methyl-CpG binding protein
MBD1 protein.
Length = 52
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 1/46 (2%)
Query: 419 VLRRKRCGVCEACQL-PDCGECNACRAMAKFGGHGRTKKACVRRLC 463
+ +R CG C ACQ+ DCG C+ C C RR C
Sbjct: 2 MFKRVGCGECAACQVTEDCGACSTCLLQLPHDVASGLFCKCERRRC 47
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.136 0.415
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 197,402,125
Number of Sequences: 224733
Number of extensions: 8571549
Number of successful extensions: 26494
Number of sequences better than 10.0: 57
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 26231
Number of HSP's gapped (non-prelim): 127
length of query: 1314
length of database: 73,234,838
effective HSP length: 99
effective length of query: 1215
effective length of database: 50,986,271
effective search space: 61948319265
effective search space used: 61948319265
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)
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