Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005356-TA|BGIBMGA005356-PA|IPR001128|Cytochrome P450,
IPR002401|E-class P450, group I
(474 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 104 8e-22
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 104 8e-22
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 104 8e-22
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 103 2e-21
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 102 2e-21
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 88 5e-17
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 86 3e-16
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 84 9e-16
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 83 2e-15
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 83 3e-15
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 83 3e-15
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 83 3e-15
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 82 5e-15
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 78 6e-14
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 77 2e-13
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 77 2e-13
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 77 2e-13
AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 77 2e-13
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 77 2e-13
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 77 2e-13
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 77 2e-13
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 77 2e-13
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 77 2e-13
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 77 2e-13
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 77 2e-13
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 77 2e-13
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 77 2e-13
BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein. 73 3e-12
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 73 3e-12
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 69 5e-11
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 68 6e-11
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 68 6e-11
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 68 6e-11
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 68 6e-11
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 68 6e-11
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 68 6e-11
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 68 6e-11
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 68 6e-11
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 68 6e-11
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 68 6e-11
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 68 8e-11
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 66 3e-10
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 66 3e-10
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 66 3e-10
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 66 3e-10
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 66 3e-10
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 66 3e-10
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 66 3e-10
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 64 8e-10
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 64 8e-10
AJ431381-1|CAD24089.1| 186|Homo sapiens steroid 11-beta-hydroxy... 63 2e-09
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 62 3e-09
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 62 3e-09
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 62 3e-09
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 62 3e-09
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 62 5e-09
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 61 1e-08
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 60 1e-08
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 60 1e-08
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 60 2e-08
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 60 2e-08
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 60 2e-08
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 60 2e-08
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 60 2e-08
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 60 2e-08
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 60 2e-08
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 60 2e-08
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 60 2e-08
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 60 2e-08
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 60 2e-08
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 60 2e-08
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 60 2e-08
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 60 2e-08
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 60 2e-08
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 60 2e-08
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 60 2e-08
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 60 2e-08
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 60 2e-08
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 59 3e-08
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 58 7e-08
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 58 9e-08
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 57 2e-07
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 57 2e-07
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 57 2e-07
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 57 2e-07
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 57 2e-07
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 57 2e-07
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 57 2e-07
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 57 2e-07
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 57 2e-07
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 57 2e-07
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 56 4e-07
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 56 4e-07
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 56 4e-07
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 56 4e-07
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 56 4e-07
AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 56 4e-07
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 56 4e-07
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 56 4e-07
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 54 8e-07
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 54 8e-07
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 54 1e-06
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 54 1e-06
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 54 1e-06
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 52 6e-06
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 52 6e-06
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 50 1e-05
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 50 2e-05
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 50 2e-05
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 50 2e-05
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 50 2e-05
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 50 2e-05
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 50 2e-05
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 50 2e-05
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 49 3e-05
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 49 4e-05
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 49 4e-05
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 49 4e-05
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 49 4e-05
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 49 4e-05
BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 49 4e-05
BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 49 4e-05
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 49 4e-05
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 49 4e-05
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 49 4e-05
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 49 4e-05
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 49 4e-05
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 49 4e-05
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 49 4e-05
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 49 4e-05
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 49 4e-05
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 49 4e-05
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 49 4e-05
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 49 4e-05
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 49 4e-05
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 49 4e-05
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 49 4e-05
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 49 4e-05
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 49 4e-05
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 49 4e-05
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 49 4e-05
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 49 4e-05
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 49 4e-05
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 49 4e-05
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 49 4e-05
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 49 4e-05
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 49 4e-05
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 49 4e-05
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 49 4e-05
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 49 4e-05
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 49 4e-05
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 49 4e-05
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 49 4e-05
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 49 4e-05
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 49 4e-05
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 48 5e-05
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 48 5e-05
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 48 5e-05
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 48 5e-05
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 48 5e-05
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 48 5e-05
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 48 5e-05
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 48 5e-05
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 48 5e-05
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 48 5e-05
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 48 5e-05
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 48 5e-05
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 48 5e-05
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 48 9e-05
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 47 1e-04
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 47 1e-04
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 46 3e-04
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 46 3e-04
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 46 3e-04
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 46 3e-04
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 46 3e-04
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 46 3e-04
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 46 3e-04
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 46 3e-04
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 46 3e-04
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 46 3e-04
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 46 3e-04
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 46 3e-04
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 46 3e-04
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 46 3e-04
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 46 3e-04
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 46 3e-04
BC001776-1|AAH01776.1| 217|Homo sapiens CYP27B1 protein protein. 46 3e-04
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 46 3e-04
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 46 3e-04
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 46 3e-04
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 46 3e-04
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 46 3e-04
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 46 3e-04
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 46 3e-04
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 46 3e-04
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 45 7e-04
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 45 7e-04
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 45 7e-04
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 45 7e-04
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 45 7e-04
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 45 7e-04
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 45 7e-04
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 45 7e-04
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 45 7e-04
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 45 7e-04
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 45 7e-04
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 45 7e-04
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 45 7e-04
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 44 9e-04
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 44 9e-04
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 44 0.001
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 44 0.001
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 44 0.001
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 44 0.001
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 43 0.002
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 43 0.002
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 43 0.002
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 43 0.002
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 43 0.002
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 43 0.002
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 43 0.002
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 43 0.002
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 43 0.002
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 43 0.002
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 43 0.002
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 43 0.002
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 43 0.003
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 43 0.003
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 43 0.003
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 43 0.003
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 42 0.004
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 42 0.004
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 42 0.004
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 42 0.004
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 42 0.004
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 42 0.004
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 42 0.004
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 42 0.004
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 42 0.004
AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 42 0.004
AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 42 0.004
AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 42 0.004
AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 42 0.004
AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 42 0.004
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 42 0.004
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 42 0.004
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 42 0.004
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 42 0.005
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 42 0.005
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 42 0.005
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 42 0.005
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 42 0.005
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 42 0.005
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 42 0.006
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 42 0.006
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 42 0.006
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 42 0.006
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 42 0.006
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 41 0.011
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 41 0.011
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 41 0.011
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 41 0.011
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 41 0.011
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 41 0.011
AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, famil... 41 0.011
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 41 0.011
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 41 0.011
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 41 0.011
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 40 0.014
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 40 0.014
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 40 0.014
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 40 0.014
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 40 0.014
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 40 0.014
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 40 0.014
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 40 0.014
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 40 0.014
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 40 0.014
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 40 0.014
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 40 0.014
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 40 0.014
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 40 0.014
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 40 0.014
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 40 0.014
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 40 0.019
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 40 0.019
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 40 0.019
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 40 0.019
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 40 0.019
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 40 0.019
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 40 0.019
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 40 0.019
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 40 0.019
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 40 0.019
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 40 0.025
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 39 0.033
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 39 0.033
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 39 0.033
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 39 0.033
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 39 0.033
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 39 0.033
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 39 0.033
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 39 0.033
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 39 0.044
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 38 0.058
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 38 0.058
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 38 0.058
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 38 0.058
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 38 0.058
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 38 0.058
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 38 0.058
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 38 0.058
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 38 0.058
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 38 0.058
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 38 0.058
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 38 0.058
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 38 0.058
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 38 0.077
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 38 0.10
AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family... 38 0.10
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 37 0.13
BC128535-1|AAI28536.1| 143|Homo sapiens LOC283480 protein protein. 37 0.13
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 37 0.18
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 36 0.23
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 36 0.23
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 36 0.23
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 36 0.23
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 36 0.23
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 36 0.23
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 36 0.23
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 36 0.23
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 36 0.23
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 35 0.54
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 35 0.72
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 34 0.95
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 34 0.95
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 34 0.95
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 34 0.95
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 34 0.95
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 34 0.95
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 34 0.95
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 34 0.95
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 34 0.95
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 34 1.2
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 34 1.2
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 34 1.2
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 33 1.7
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 33 1.7
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 33 1.7
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 33 2.2
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 33 2.2
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 33 2.2
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 33 2.2
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 33 2.2
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 33 2.9
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 33 2.9
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 33 2.9
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 33 2.9
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 33 2.9
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 33 2.9
BC096259-1|AAH96259.1| 443|Homo sapiens CYP2C18 protein protein. 33 2.9
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 33 2.9
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 33 2.9
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 33 2.9
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 31 6.7
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 31 6.7
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 31 8.8
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 104 bits (249), Expect = 8e-22
Identities = 104/401 (25%), Positives = 169/401 (42%), Gaps = 54/401 (13%)
Query: 37 EQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVNPALLLPK 96
EQV R E P+R ++ +R Q + +G +G W + R +N LL P
Sbjct: 115 EQVMRQEGKYPVRNDMELWKEHRDQ-----HDLTYGPFTTEGHHWYQLRQALNQRLLKPA 169
Query: 97 LVKLYAPGIDEIAQDFVQRLSQITHDDA---YIKDNFELELTKFSLEATALVALGSRLGC 153
LY +E+ DF+ RL Q+ + A + D +L F+LEA + R+GC
Sbjct: 170 EAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQL-FYYFALEAICYILFEKRIGC 228
Query: 154 LKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSPWRYIATPAYKMVIEAYDTQWEISMMY 213
L+ S+ D ++S +F+ + P W P +K ++ ++ +
Sbjct: 229 LQRSIPEDTVT--FVRSIGLMFQNSLYATFLPK-WTRPVLPFWKRYLDGWNAIFSFG--- 282
Query: 214 INHARKKLEQRGYDIPEEEKSVLEKLIAIDEKVAVMMASEMLLAGIDTV-CGQFNHFIVF 272
KKL IDEK+ M A ++ AG D + + HF++
Sbjct: 283 -----KKL--------------------IDEKLEDMEA-QLQAAGPDGIQVSGYLHFLLA 316
Query: 273 SFMIIXXXXXXXXXXXXPAFTQVSFVT-TSLLFNLAMNQKVQDKLREEI----------R 321
S + A + T T L++L+ + ++Q+ L EE+ +
Sbjct: 317 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQ 376
Query: 322 TSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEK 381
+ + +A LKE LRL VVP N R ++ V G+ PK + + +SR
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436
Query: 382 FYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
+ +PE F P RWL S P HP ++PFG+GVR+C
Sbjct: 437 AFSEPESFQPHRWL-RNSQPATPRIQHPFGSVPFGYGVRAC 476
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 104 bits (249), Expect = 8e-22
Identities = 104/401 (25%), Positives = 169/401 (42%), Gaps = 54/401 (13%)
Query: 37 EQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVNPALLLPK 96
EQV R E P+R ++ +R Q + +G +G W + R +N LL P
Sbjct: 115 EQVMRQEGKYPVRNDMELWKEHRDQ-----HDLTYGPFTTEGHHWYQLRQALNQRLLKPA 169
Query: 97 LVKLYAPGIDEIAQDFVQRLSQITHDDA---YIKDNFELELTKFSLEATALVALGSRLGC 153
LY +E+ DF+ RL Q+ + A + D +L F+LEA + R+GC
Sbjct: 170 EAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQL-FYYFALEAICYILFEKRIGC 228
Query: 154 LKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSPWRYIATPAYKMVIEAYDTQWEISMMY 213
L+ S+ D ++S +F+ + P W P +K ++ ++ +
Sbjct: 229 LQRSIPEDTVT--FVRSIGLMFQNSLYATFLPK-WTRPVLPFWKRYLDGWNAIFSFG--- 282
Query: 214 INHARKKLEQRGYDIPEEEKSVLEKLIAIDEKVAVMMASEMLLAGIDTV-CGQFNHFIVF 272
KKL IDEK+ M A ++ AG D + + HF++
Sbjct: 283 -----KKL--------------------IDEKLEDMEA-QLQAAGPDGIQVSGYLHFLLA 316
Query: 273 SFMIIXXXXXXXXXXXXPAFTQVSFVT-TSLLFNLAMNQKVQDKLREEI----------R 321
S + A + T T L++L+ + ++Q+ L EE+ +
Sbjct: 317 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQ 376
Query: 322 TSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEK 381
+ + +A LKE LRL VVP N R ++ V G+ PK + + +SR
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436
Query: 382 FYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
+ +PE F P RWL S P HP ++PFG+GVR+C
Sbjct: 437 AFSEPESFQPHRWL-RNSQPATPRIQHPFGSVPFGYGVRAC 476
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 104 bits (249), Expect = 8e-22
Identities = 104/401 (25%), Positives = 169/401 (42%), Gaps = 54/401 (13%)
Query: 37 EQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVNPALLLPK 96
EQV R E P+R ++ +R Q + +G +G W + R +N LL P
Sbjct: 115 EQVMRQEGKYPVRNDMELWKEHRDQ-----HDLTYGPFTTEGHHWYQLRQALNQRLLKPA 169
Query: 97 LVKLYAPGIDEIAQDFVQRLSQITHDDA---YIKDNFELELTKFSLEATALVALGSRLGC 153
LY +E+ DF+ RL Q+ + A + D +L F+LEA + R+GC
Sbjct: 170 EAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQL-FYYFALEAICYILFEKRIGC 228
Query: 154 LKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSPWRYIATPAYKMVIEAYDTQWEISMMY 213
L+ S+ D ++S +F+ + P W P +K ++ ++ +
Sbjct: 229 LQRSIPEDTVT--FVRSIGLMFQNSLYATFLPK-WTRPVLPFWKRYLDGWNAIFSFG--- 282
Query: 214 INHARKKLEQRGYDIPEEEKSVLEKLIAIDEKVAVMMASEMLLAGIDTV-CGQFNHFIVF 272
KKL IDEK+ M A ++ AG D + + HF++
Sbjct: 283 -----KKL--------------------IDEKLEDMEA-QLQAAGPDGIQVSGYLHFLLA 316
Query: 273 SFMIIXXXXXXXXXXXXPAFTQVSFVT-TSLLFNLAMNQKVQDKLREEI----------R 321
S + A + T T L++L+ + ++Q+ L EE+ +
Sbjct: 317 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQ 376
Query: 322 TSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEK 381
+ + +A LKE LRL VVP N R ++ V G+ PK + + +SR
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 436
Query: 382 FYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
+ +PE F P RWL S P HP ++PFG+GVR+C
Sbjct: 437 AFSEPESFQPHRWL-RNSQPATPRIQHPFGSVPFGYGVRAC 476
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 103 bits (246), Expect = 2e-21
Identities = 104/401 (25%), Positives = 169/401 (42%), Gaps = 54/401 (13%)
Query: 37 EQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVNPALLLPK 96
EQV R E P+R ++ +R Q + +G +G W + R +N LL P
Sbjct: 114 EQVMRQEGKYPVRNDMELWKEHRDQ-----HDLTYGPFTTEGHHWYQLRQALNQRLLKPA 168
Query: 97 LVKLYAPGIDEIAQDFVQRLSQITHDDA---YIKDNFELELTKFSLEATALVALGSRLGC 153
LY +E+ DF+ RL Q+ + A + D +L F+LEA + R+GC
Sbjct: 169 ERALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQL-FYYFALEAICYILFEKRIGC 227
Query: 154 LKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSPWRYIATPAYKMVIEAYDTQWEISMMY 213
L+ S+ D ++S +F+ + P W P +K ++ ++ +
Sbjct: 228 LQRSIPEDTVT--FVRSIGLMFQNSLYATFLPK-WTRPVLPFWKRYLDGWNAIFSFG--- 281
Query: 214 INHARKKLEQRGYDIPEEEKSVLEKLIAIDEKVAVMMASEMLLAGIDTV-CGQFNHFIVF 272
KKL IDEK+ M A ++ AG D + + HF++
Sbjct: 282 -----KKL--------------------IDEKLEDMEA-QLQAAGPDGIQVSGYLHFLLA 315
Query: 273 SFMIIXXXXXXXXXXXXPAFTQVSFVT-TSLLFNLAMNQKVQDKLREEI----------R 321
S + A + T T L++L+ + ++Q+ L EE+ +
Sbjct: 316 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQ 375
Query: 322 TSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEK 381
+ + +A LKE LRL VVP N R ++ V G+ PK + + +SR
Sbjct: 376 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPT 435
Query: 382 FYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
+ +PE F P RWL S P HP ++PFG+GVR+C
Sbjct: 436 AFSEPESFQPHRWL-RNSQPATPRIQHPFGSVPFGYGVRAC 475
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 102 bits (245), Expect = 2e-21
Identities = 104/401 (25%), Positives = 168/401 (41%), Gaps = 54/401 (13%)
Query: 37 EQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVNPALLLPK 96
EQV R E P+R ++ +R Q + +G +G W + R +N LL P
Sbjct: 115 EQVMRQEGKYPVRNDMELWKEHRDQ-----HDLTYGPFTTEGHHWYQLRQALNQRLLKPA 169
Query: 97 LVKLYAPGIDEIAQDFVQRLSQITHDDA---YIKDNFELELTKFSLEATALVALGSRLGC 153
LY +E+ DF+ RL Q+ + A + D +L F+LEA + R+GC
Sbjct: 170 EAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQL-FYYFALEAICYILFEKRIGC 228
Query: 154 LKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSPWRYIATPAYKMVIEAYDTQWEISMMY 213
L+ S+ D ++S +F+ + P W P +K ++ ++ +
Sbjct: 229 LQRSIPEDTVT--FVRSIGLMFQNSLYATFLPK-WTRPVLPFWKRYLDGWNAIFSFG--- 282
Query: 214 INHARKKLEQRGYDIPEEEKSVLEKLIAIDEKVAVMMASEMLLAGIDTV-CGQFNHFIVF 272
KKL IDEK+ M A ++ AG D + + HF++
Sbjct: 283 -----KKL--------------------IDEKLEDMEA-QLQAAGPDGIQVSGYLHFLLA 316
Query: 273 SFMIIXXXXXXXXXXXXPAFTQVSFVT-TSLLFNLAMNQKVQDKLREEI----------R 321
S + A + T T L++L+ + ++Q L EE+ +
Sbjct: 317 SGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQ 376
Query: 322 TSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEK 381
+ + +A LKE LRL VVP N R ++ V G+ PK + + +SR
Sbjct: 377 HKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVSRDPT 436
Query: 382 FYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
+ +PE F P RWL S P HP ++PFG+GVR+C
Sbjct: 437 AFSEPESFQPHRWL-RNSQPATPRIQHPFGSVPFGYGVRAC 476
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 88.2 bits (209), Expect = 5e-17
Identities = 95/394 (24%), Positives = 165/394 (41%), Gaps = 42/394 (10%)
Query: 30 LFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVN 89
L P E +YR E P R + YR RK YG L+ +G +W+ R+
Sbjct: 109 LGSPCLLEALYRTESV-PQRLEIKPWKAYR-DYRKEGYG----LLILEGEDWQRVRSAFQ 162
Query: 90 PALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELELTKFSLEATALVALGS 149
L+ P V I+E+ DF+ R+ ++ + +++D + EL K+S E+ LV
Sbjct: 163 KKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYS-ELNKWSFESICLVLYEK 221
Query: 150 RLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SPWRYIATPAYKMVIEAYDTQWE 208
R G L+ + + A + + + + ++ + P + + T ++ A+DT ++
Sbjct: 222 RFGLLQKNAGDE--AVNFIMAIKTMMSTFGRMMVTPVELHKSLNTKVWQGHTLAWDTIFK 279
Query: 209 ISMMYINHARKKLEQRGYDIPEEEKSVLEKLIAIDEKVAVMMASEMLLAGIDTVCGQFNH 268
I++ +LE+ + + + +K +E+ LA ++T
Sbjct: 280 SVKACIDN---RLEKYSQQPSADFLCDIYHQNRLSKKELYAAVTELQLAAVETTAN---- 332
Query: 269 FIVFSFMIIXXXXXXXXXXXXPAFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK 328
S M I ++ V L NQ+ ++ E++R
Sbjct: 333 ----SLMWILYNLSRNPQVQQKLLKEIQSV-------LPENQRPRE---EDLRNMP---- 374
Query: 329 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y +ACLKE++RL VP R + ++G Y +PKG ++ + L SE + +
Sbjct: 375 -YLKACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQ 433
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PERWL EK +P LPFG G R C
Sbjct: 434 FRPERWLQEKE------KINPFAHLPFGVGKRMC 461
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 85.8 bits (203), Expect = 3e-16
Identities = 100/393 (25%), Positives = 178/393 (45%), Gaps = 44/393 (11%)
Query: 37 EQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVNPALLLPK 96
E V + ++ + L P +L+ + +R+ R G G+ GPEWR R ++NP +L PK
Sbjct: 95 EDVEKLQQVDSLHPCRMILEPW-VAIRQHR-GHKCGVFLLNGPEWRFNRLRLNPDVLSPK 152
Query: 97 LVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELE--LTKFSLEATALVALGSRLGCL 154
V+ + P +D +A+DF Q L + +A +++ + +++EA+ L G RLG +
Sbjct: 153 AVQRFLPMVDAVARDFSQALRKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLV 212
Query: 155 KDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SPWRYIATPAYKMVIEAYDTQWEISMMY 213
S S + + + +F+ T +L P S R+I+ +K EA W+ Y
Sbjct: 213 GHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEA----WDCIFQY 266
Query: 214 INHARKKLEQR-GYDIPEEEKSVL-EKLIAIDEKVAVMMASEM-LLAG-IDTVCGQFNHF 269
++ +K+ Q ++ P+ ++ E L+ + + + A+ M L AG +DT
Sbjct: 267 GDNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTT------- 319
Query: 270 IVFSFMIIXXXXXXXXXXXXPAFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR 329
+F ++ P Q+ SL ++++ Q K E+ + K
Sbjct: 320 ---AFPLL---MTLFELARNPDVQQI-LRKESLAAAASISEHPQ-KATTELPLLRAALKE 371
Query: 330 YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEF 389
R L L VV ++L ++ Y+IP G V L R+ +P+PE +
Sbjct: 372 TLR-LYPVGLFLERVVSSDL-------VLQNYHIPAGTLVQVFLYSLGRNAALFPRPERY 423
Query: 390 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
P+RWL + G+ L +PFGFG+R C
Sbjct: 424 NPQRWLDIR------GSGRNLHHVPFGFGMRQC 450
>X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (11 Beta). ).
Length = 503
Score = 84.2 bits (199), Expect = 9e-16
Identities = 104/419 (24%), Positives = 184/419 (43%), Gaps = 49/419 (11%)
Query: 11 KFGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGL 70
+ GP+ + D M+ + P+ E++ + + +P R + YR Q R + G
Sbjct: 74 ELGPIFRYD--LGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR-QHRGHKCGVF 130
Query: 71 HGLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNF 130
L+N GPEWR R ++NP +L P V+ + P +D +A+DF Q L + +A
Sbjct: 131 --LLN--GPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTL 186
Query: 131 ELE--LTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SP 187
+++ + +++EA+ L G RLG + S S + + + +F+ T +L P S
Sbjct: 187 DVQPSIFHYTIEASNLALFGERLGLVGHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSL 244
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQR-GYDIPEEEKSVLEKLIAIDE-- 244
R+ + +K EA W+ Y ++ +K+ Q + P++ S++ +L+ E
Sbjct: 245 SRWTSPKVWKEHFEA----WDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS 300
Query: 245 KVAVMMASEMLLAG-IDTVCGQFNHFIVFSFMIIXXXXXXXXXXXXPAFTQVSFVTTSLL 303
A+ S L AG +DT VF +++ A Q S +
Sbjct: 301 PDAIKANSMELTAGSVDTT--------VFP-LLMTLFELARNPNVQQALRQESLAAAA-- 349
Query: 304 FNLAMNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYI 363
++++ Q K E+ + K R L L VV ++L ++ Y+I
Sbjct: 350 ---SISEHPQ-KATTELPLLRAALKETLR-LYPVGLFLERVVSSDL-------VLQNYHI 397
Query: 364 PKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
P G V L R+ +P+PE + P+RWL + G+ +PFGFG+R C
Sbjct: 398 PAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 450
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 83.4 bits (197), Expect = 2e-15
Identities = 99/393 (25%), Positives = 176/393 (44%), Gaps = 44/393 (11%)
Query: 37 EQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVNPALLLPK 96
E V + ++ + L P +L+ + R+ R G G+ GPEWR R ++NP +L PK
Sbjct: 95 EDVEKLQQVDSLHPCRMILEPW-VAYRQHR-GHKCGVFLLNGPEWRFNRLRLNPDVLSPK 152
Query: 97 LVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELE--LTKFSLEATALVALGSRLGCL 154
V+ + P +D +A+DF Q L + +A +++ + +++EA+ L G RLG +
Sbjct: 153 AVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLV 212
Query: 155 KDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SPWRYIATPAYKMVIEAYDTQWEISMMY 213
S S + + + +F+ T +L P S R+I+ +K EA W+ Y
Sbjct: 213 GHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSLSRWISPKVWKEHFEA----WDCIFQY 266
Query: 214 INHARKKLEQR-GYDIPEEEKSVL-EKLIAIDEKVAVMMASEM-LLAG-IDTVCGQFNHF 269
++ +K+ Q ++ P+ ++ E L+ + + + A+ M L AG +DT
Sbjct: 267 GDNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTT------- 319
Query: 270 IVFSFMIIXXXXXXXXXXXXPAFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR 329
+F ++ P Q+ SL ++++ Q K E+ + K
Sbjct: 320 ---AFPLL---MTLFELARNPDVQQI-LRQESLAAAASISEHPQ-KATTELPLLRAALKE 371
Query: 330 YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEF 389
R L L VV ++L ++ Y+IP G V L R+ +P+PE +
Sbjct: 372 TLR-LYPVGLFLERVVSSDL-------VLQNYHIPAGTLVQVFLYSLGRNAALFPRPERY 423
Query: 390 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
P+RWL + G+ +PFGFG+R C
Sbjct: 424 NPQRWLDIR------GSGRNFHHVPFGFGMRQC 450
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 82.6 bits (195), Expect = 3e-15
Identities = 99/393 (25%), Positives = 175/393 (44%), Gaps = 44/393 (11%)
Query: 37 EQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVNPALLLPK 96
E V + ++ + L P +L+ + R+ R G G+ GPEWR R ++NP +L PK
Sbjct: 95 EDVEKLQQVDSLHPCRMILEPW-VAYRQHR-GHKCGVFLLNGPEWRFNRLRLNPDVLSPK 152
Query: 97 LVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELE--LTKFSLEATALVALGSRLGCL 154
V+ + P +D +A+DF Q L + +A +++ + +++EA+ L G RLG +
Sbjct: 153 AVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLV 212
Query: 155 KDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SPWRYIATPAYKMVIEAYDTQWEISMMY 213
S S + + + +F+ T +L P S R+I +K EA W+ Y
Sbjct: 213 GHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSLSRWIRPKVWKEHFEA----WDCIFQY 266
Query: 214 INHARKKLEQR-GYDIPEEEKSVL-EKLIAIDEKVAVMMASEM-LLAG-IDTVCGQFNHF 269
++ +K+ Q ++ P+ ++ E L+ + + + A+ M L AG +DT
Sbjct: 267 GDNCIQKIYQELAFNRPQHYTGIVAELLLKAELSLEAIKANSMELTAGSVDTT------- 319
Query: 270 IVFSFMIIXXXXXXXXXXXXPAFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR 329
+F ++ P Q+ SL ++++ Q K E+ + K
Sbjct: 320 ---AFPLL---MTLFELARNPDVQQI-LRQESLAAAASISEHPQ-KATTELPLLRAALKE 371
Query: 330 YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEF 389
R L L VV ++L ++ Y+IP G V L R+ +P+PE +
Sbjct: 372 TLR-LYPVGLFLERVVSSDL-------VLQNYHIPAGTLVQVFLYSLGRNAALFPRPERY 423
Query: 390 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
P+RWL + G+ +PFGFG+R C
Sbjct: 424 NPQRWLDIR------GSGRNFHHVPFGFGMRQC 450
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 82.6 bits (195), Expect = 3e-15
Identities = 103/419 (24%), Positives = 183/419 (43%), Gaps = 49/419 (11%)
Query: 11 KFGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGL 70
+ GP+ + D M+ + P+ E++ + + +P R + YR Q R + G
Sbjct: 74 ELGPIFRYD--LGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR-QHRGHKCGVF 130
Query: 71 HGLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNF 130
L+N GPEWR R ++NP +L P V+ + P +D +A+DF Q L + +A
Sbjct: 131 --LLN--GPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTL 186
Query: 131 ELE--LTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SP 187
+++ + +++EA+ L G RLG + S S + + + +F+ T +L P S
Sbjct: 187 DVQPSIFHYTIEASNLALFGERLGLVGHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSL 244
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQR-GYDIPEEEKSVLEKLIAIDE-- 244
R+ + +K EA W+ Y ++ +K+ Q + P++ S++ +L+ E
Sbjct: 245 SRWTSPKVWKEHFEA----WDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS 300
Query: 245 KVAVMMASEMLLAG-IDTVCGQFNHFIVFSFMIIXXXXXXXXXXXXPAFTQVSFVTTSLL 303
A+ S L AG +DT VF +++ A Q S +
Sbjct: 301 PDAIKANSMELTAGSVDTT--------VFP-LLMTLFELARNPNVQQALRQESLAAAA-- 349
Query: 304 FNLAMNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYI 363
++++ Q K E+ + K R L L V ++L ++ Y+I
Sbjct: 350 ---SISEHPQ-KATTELPLLRAALKETLR-LYPVGLFLERVASSDL-------VLQNYHI 397
Query: 364 PKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
P G V L R+ +P+PE + P+RWL + G+ +PFGFG+R C
Sbjct: 398 PAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 450
>BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 503
Score = 82.6 bits (195), Expect = 3e-15
Identities = 103/419 (24%), Positives = 183/419 (43%), Gaps = 49/419 (11%)
Query: 11 KFGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGL 70
+ GP+ + D M+ + P+ E++ + + +P R + YR Q R + G
Sbjct: 74 ELGPIFRYD--LGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR-QHRGHKCGVF 130
Query: 71 HGLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNF 130
L+N GPEWR R ++NP +L P V+ + P +D +A+DF Q L + +A
Sbjct: 131 --LLN--GPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTL 186
Query: 131 ELE--LTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SP 187
+++ + +++EA+ L G RLG + S S + + + +F+ T +L P S
Sbjct: 187 DVQPSIFHYTIEASNLALFGERLGLVGHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSL 244
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQR-GYDIPEEEKSVLEKLIAIDE-- 244
R+ + +K EA W+ Y ++ +K+ Q + P++ S++ +L+ E
Sbjct: 245 SRWTSPKVWKEHFEA----WDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS 300
Query: 245 KVAVMMASEMLLAG-IDTVCGQFNHFIVFSFMIIXXXXXXXXXXXXPAFTQVSFVTTSLL 303
A+ S L AG +DT VF +++ A Q S +
Sbjct: 301 PDAIKANSMELTAGSVDTT--------VFP-LLMTLFELARNPNVQQALRQESLAAAA-- 349
Query: 304 FNLAMNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYI 363
++++ Q K E+ + K R L L V ++L ++ Y+I
Sbjct: 350 ---SISEHPQ-KATTELPLLRAALKETLR-LYPVGLFLERVASSDL-------VLQNYHI 397
Query: 364 PKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
P G V L R+ +P+PE + P+RWL + G+ +PFGFG+R C
Sbjct: 398 PAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 450
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 81.8 bits (193), Expect = 5e-15
Identities = 103/419 (24%), Positives = 183/419 (43%), Gaps = 49/419 (11%)
Query: 11 KFGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGL 70
+ GP+ + D M+ + P+ E++ + + +P R + YR Q R + G
Sbjct: 74 ELGPIFRYD--LGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR-QHRGHKCGVF 130
Query: 71 HGLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNF 130
L+N GPEWR R ++NP +L P V+ + P +D +A+DF Q L + +A
Sbjct: 131 --LLN--GPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTL 186
Query: 131 ELE--LTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SP 187
+++ + +++EA+ L G RLG + S S + + + +F+ T +L P S
Sbjct: 187 DVQPSIFHYTIEASNLALFGERLGLVGHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSL 244
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQR-GYDIPEEEKSVLEKLIAIDE-- 244
R+ + +K EA W+ Y ++ +K+ Q + P++ S++ +L+ E
Sbjct: 245 SRWTSPKVWKEHFEA----WDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS 300
Query: 245 KVAVMMASEMLLAG-IDTVCGQFNHFIVFSFMIIXXXXXXXXXXXXPAFTQVSFVTTSLL 303
A+ S L AG +DT VF +++ A Q S +
Sbjct: 301 PDAIKANSMELTAGSMDTT--------VFP-LLMTLFELARNPNVQQALRQESLAAAA-- 349
Query: 304 FNLAMNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYI 363
++++ Q K E+ + K R L L V ++L ++ Y+I
Sbjct: 350 ---SISEHPQ-KATTELPLLRAALKETLR-LYPVGLFLERVASSDL-------VLQNYHI 397
Query: 364 PKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
P G V L R+ +P+PE + P+RWL + G+ +PFGFG+R C
Sbjct: 398 PAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFGFGMRQC 450
>BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein.
Length = 574
Score = 78.2 bits (184), Expect = 6e-14
Identities = 92/366 (25%), Positives = 159/366 (43%), Gaps = 46/366 (12%)
Query: 68 GGLHGLIN----AQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDD 123
GG+HG GPEWR R ++NP +L P V+ + P +D +A+DF Q L + +
Sbjct: 191 GGIHGAPTHSGCRNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQN 250
Query: 124 AYIKDNFELE--LTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKL 181
A +++ + +++EA+ L G RLG + S S + + + +F+ T +L
Sbjct: 251 ARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSS--ASLNFLHALEVMFKSTVQL 308
Query: 182 EIRP-SPWRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQR-GYDIPEEEKSVLEKL 239
P S R+ + +K EA W+ Y ++ +K+ Q + P++ S++ +L
Sbjct: 309 MFMPRSLSRWTSPKVWKEHFEA----WDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAEL 364
Query: 240 IAIDE--KVAVMMASEMLLAG-IDTVCGQFNHFIVFSFMIIXXXXXXXXXXXXPAFTQVS 296
+ E A+ S L AG +DT VF +++ A Q S
Sbjct: 365 LLNAELSPDAIKANSMELTAGSVDTT--------VFP-LLMTLFELARNPNVQQALRQES 415
Query: 297 FVTTSLLFNLAMNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDH 356
+ ++++ Q K E+ + K R L L V ++L
Sbjct: 416 LAAAA-----SISEHPQ-KATTELPLLRAALKETLR-LYPVGLFLERVASSDL------- 461
Query: 357 IVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFG 416
++ Y+IP G V L R+ +P+PE + P+RWL + G+ +PFG
Sbjct: 462 VLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIR------GSGRNFYHVPFG 515
Query: 417 FGVRSC 422
FG+R C
Sbjct: 516 FGMRQC 521
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 76.6 bits (180), Expect = 2e-13
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 16/131 (12%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYKR--------YFRACLKEALRLRHVVPANLRR 351
+L+NL+ N +VQ KL +EI++ E+ R Y +ACLKE++RL VP R
Sbjct: 81 ILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRT 140
Query: 352 THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLV 411
+ ++G Y +PKG ++ + L SE + +F PERWL EK +P
Sbjct: 141 LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKE------KINPFA 194
Query: 412 TLPFGFGVRSC 422
LPFG G R C
Sbjct: 195 HLPFGVGKRMC 205
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 76.6 bits (180), Expect = 2e-13
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 16/131 (12%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYKR--------YFRACLKEALRLRHVVPANLRR 351
+L+NL+ N +VQ KL +EI++ E+ R Y +ACLKE++RL VP R
Sbjct: 196 ILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRT 255
Query: 352 THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLV 411
+ ++G Y +PKG ++ + L SE + +F PERWL EK +P
Sbjct: 256 LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKE------KINPFA 309
Query: 412 TLPFGFGVRSC 422
LPFG G R C
Sbjct: 310 HLPFGVGKRMC 320
Score = 43.2 bits (97), Expect = 0.002
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 77 QGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELELTK 136
+G +W+ R+ L+ P V I+E+ DF+ R+ ++ + +++D + EL K
Sbjct: 9 EGEDWQRVRSAFQKKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYS-ELNK 67
Query: 137 FSLEATALVALGSRLGCLK 155
+S E+ LV R G L+
Sbjct: 68 WSFESICLVLYEKRFGLLQ 86
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 76.6 bits (180), Expect = 2e-13
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 16/131 (12%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYKR--------YFRACLKEALRLRHVVPANLRR 351
+L+NL+ N +VQ KL +EI++ E+ R Y +ACLKE++RL VP R
Sbjct: 338 ILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRT 397
Query: 352 THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLV 411
+ ++G Y +PKG ++ + L SE + +F PERWL EK +P
Sbjct: 398 LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKE------KINPFA 451
Query: 412 TLPFGFGVRSC 422
LPFG G R C
Sbjct: 452 HLPFGVGKRMC 462
Score = 55.6 bits (128), Expect = 4e-07
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 30 LFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVN 89
L P E +YR E A P R + YR RK YG L+ +G +W+ R+
Sbjct: 109 LGSPCLLEALYRTESAYPQRLEIKPWKAYR-DYRKEGYG----LLILEGEDWQRVRSAFQ 163
Query: 90 PALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELELTKFSLEATALVALGS 149
L+ P V I+E+ DF+ R+ ++ + +++D + EL K+S E+ LV
Sbjct: 164 KKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYS-ELNKWSFESICLVLYEK 222
Query: 150 RLGCLK 155
R G L+
Sbjct: 223 RFGLLQ 228
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 76.6 bits (180), Expect = 2e-13
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 16/131 (12%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYKR--------YFRACLKEALRLRHVVPANLRR 351
+L+NL+ N +VQ KL +EI++ E+ R Y +ACLKE++RL VP R
Sbjct: 196 ILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRT 255
Query: 352 THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLV 411
+ ++G Y +PKG ++ + L SE + +F PERWL EK +P
Sbjct: 256 LDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSSQFRPERWLQEKE------KINPFA 309
Query: 412 TLPFGFGVRSC 422
LPFG G R C
Sbjct: 310 HLPFGVGKRMC 320
Score = 43.2 bits (97), Expect = 0.002
Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 1/79 (1%)
Query: 77 QGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELELTK 136
+G +W+ R+ L+ P V I+E+ DF+ R+ ++ + +++D + EL K
Sbjct: 9 EGEDWQRVRSAFQKKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYS-ELNK 67
Query: 137 FSLEATALVALGSRLGCLK 155
+S E+ LV R G L+
Sbjct: 68 WSFESICLVLYEKRFGLLQ 86
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/261 (26%), Positives = 114/261 (43%), Gaps = 20/261 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRPSP 187
D E KF LE A V LGSRLGCL+ + D +++ +F T P
Sbjct: 185 D-VAGEFYKFGLEGIAAVLLGSRLGCLEAQVPPD--TETFIRAVGSVFVSTLLTMAMPHW 241
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPE---EEKSVLEKLIAIDE 244
R++ + + +D + + ++ + R PE E + L + +E
Sbjct: 242 LRHLVPGPWGRLCRDWDQMFAFAQRHVERREAEAAMRNGGQPEKDLESGAHLTHFLFREE 301
Query: 245 KVAVMM---ASEMLLAGIDTV 262
A + +E+LLAG+DTV
Sbjct: 302 LPAQSILGNVTELLLAGVDTV 322
Score = 72.5 bits (170), Expect = 3e-12
Identities = 41/91 (45%), Positives = 48/91 (52%), Gaps = 6/91 (6%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
+A +KE LRL VVP N R +D VG Y IPK V + SR +P+P F P
Sbjct: 371 KAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPNSFRP 430
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
RWL E P HP +LPFGFG RSC
Sbjct: 431 ARWLGEGPTP------HPFASLPFGFGKRSC 455
>BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein.
Length = 372
Score = 72.5 bits (170), Expect = 3e-12
Identities = 40/91 (43%), Positives = 52/91 (57%), Gaps = 4/91 (4%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
RA LKE LRL V+P N R T D ++GGY IPKG + + S ++ +P+ +EF P
Sbjct: 232 RALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRP 291
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
ERWL K D ++PFG GVRSC
Sbjct: 292 ERWL-RKGD---LDRVDNFGSIPFGHGVRSC 318
Score = 44.0 bits (99), Expect = 0.001
Identities = 38/183 (20%), Positives = 83/183 (45%), Gaps = 6/183 (3%)
Query: 85 RTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITH--DDAYIKDNFELELTKFSLEAT 142
R+ + +L PK V +Y+ ++++ D ++R+ + +D N K+S+E
Sbjct: 2 RSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGV 61
Query: 143 ALVALGSRLGCLKDSLDS-DHPARRLMKSTRDIFELTYKLEIRPSPWRYIATPAYKMVIE 201
A + SRLGCL++S+ ++ +F+ + P R ++
Sbjct: 62 ATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFIPKPWREFCR 121
Query: 202 AYDTQWEISMMYINHARKKLE---QRGYDIPEEEKSVLEKLIAIDEKVAVMMASEMLLAG 258
++D ++ S +++++ + ++ RG + + L A+ + +EMLLAG
Sbjct: 122 SWDGLFKFSQIHVDNKLRDIQYQMDRGRRVSGGLLTYLFLSQALTLQEIYANVTEMLLAG 181
Query: 259 IDT 261
+DT
Sbjct: 182 VDT 184
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 72.5 bits (170), Expect = 3e-12
Identities = 40/91 (43%), Positives = 52/91 (57%), Gaps = 4/91 (4%)
Query: 332 RACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIP 391
RA LKE LRL V+P N R T D ++GGY IPKG + + S ++ +P+ +EF P
Sbjct: 232 RALLKETLRLFPVLPGNGRVTQEDLVIGGYLIPKGTQLALCHYATSYQDENFPRAKEFRP 291
Query: 392 ERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
ERWL K D ++PFG GVRSC
Sbjct: 292 ERWL-RKGD---LDRVDNFGSIPFGHGVRSC 318
Score = 44.0 bits (99), Expect = 0.001
Identities = 38/183 (20%), Positives = 83/183 (45%), Gaps = 6/183 (3%)
Query: 85 RTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITH--DDAYIKDNFELELTKFSLEAT 142
R+ + +L PK V +Y+ ++++ D ++R+ + +D N K+S+E
Sbjct: 2 RSVLRQRILKPKDVAIYSGEVNQVIADLIKRIYLLRSQAEDGETVTNVNDLFFKYSMEGV 61
Query: 143 ALVALGSRLGCLKDSLDS-DHPARRLMKSTRDIFELTYKLEIRPSPWRYIATPAYKMVIE 201
A + SRLGCL++S+ ++ +F+ + P R ++
Sbjct: 62 ATILYESRLGCLENSIPQLTVEYIEALELMFSMFKTSMYAGAIPRWLRPFIPKPWREFCR 121
Query: 202 AYDTQWEISMMYINHARKKLE---QRGYDIPEEEKSVLEKLIAIDEKVAVMMASEMLLAG 258
++D ++ S +++++ + ++ RG + + L A+ + +EMLLAG
Sbjct: 122 SWDGLFKFSQIHVDNKLRDIQYQMDRGRRVSGGLLTYLFLSQALTLQEIYANVTEMLLAG 181
Query: 259 IDT 261
+DT
Sbjct: 182 VDT 184
>BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family
11, subfamily B, polypeptide 1 protein.
Length = 437
Score = 68.5 bits (160), Expect = 5e-11
Identities = 67/258 (25%), Positives = 123/258 (47%), Gaps = 20/258 (7%)
Query: 11 KFGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGL 70
+ GP+ + D M+ + P+ E++ + + +P R + YR Q R + G
Sbjct: 74 ELGPIFRYD--LGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYR-QHRGHKCGVF 130
Query: 71 HGLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNF 130
L+N GPEWR R ++NP +L P V+ + P +D +A+DF Q L + +A
Sbjct: 131 --LLN--GPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTL 186
Query: 131 ELE--LTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SP 187
+++ + +++EA+ L G RLG + S S + + + +F+ T +L P S
Sbjct: 187 DVQPSIFHYTIEASNLALFGERLGLVGHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSL 244
Query: 188 WRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQR-GYDIPEEEKSVLEKLIAIDE-- 244
R+ + +K EA W+ Y ++ +K+ Q + P++ S++ +L+ E
Sbjct: 245 SRWTSPKVWKEHFEA----WDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELS 300
Query: 245 KVAVMMASEMLLAG-IDT 261
A+ S L AG +DT
Sbjct: 301 PDAIKANSMELTAGSVDT 318
Score = 32.7 bits (71), Expect = 2.9
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 10/75 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRTSESNYKRY----------FRACLKEALRLRHVVPANLRRT 352
LF LA N VQ LR+E + ++ + RA LKE LRL V R
Sbjct: 327 LFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVA 386
Query: 353 HRDHIVGGYYIPKGI 367
D ++ Y+IP G+
Sbjct: 387 SSDLVLQNYHIPAGV 401
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 157 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 216
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 217 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 275
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 276 ----NIDPYIYTPFGSGPRNC 292
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 234 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 293
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 294 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 352
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 353 ----NIDPYIYTPFGSGPRNC 369
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 68.1 bits (159), Expect = 6e-11
Identities = 44/141 (31%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 67.7 bits (158), Expect = 8e-11
Identities = 44/137 (32%), Positives = 67/137 (48%), Gaps = 15/137 (10%)
Query: 296 SFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRLRHVV 345
S V + +++ LA + VQ KL+EEI N Y + E LRL +
Sbjct: 311 SSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA 370
Query: 346 PANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYG 405
R +D + G +IPKG+ V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 371 MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD----- 425
Query: 406 NAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 NIDPYIYTPFGSGPRNC 442
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 65.7 bits (153), Expect = 3e-10
Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 65.7 bits (153), Expect = 3e-10
Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 308 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 367
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 368 FPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 426
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 427 ----NIDPYIYTPFGSGPRNC 443
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 65.7 bits (153), Expect = 3e-10
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK----------RYFRACLKEALRL 341
+ S V + +++ LA + VQ K+++EI T N Y + E LRL
Sbjct: 307 YETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V R +D + G +IPKG+ V+ P+ L K++ +PE+F+PER+ + D
Sbjct: 367 FPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 65.7 bits (153), Expect = 3e-10
Identities = 44/141 (31%), Positives = 67/141 (47%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 308 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 367
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 368 FPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 426
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 427 ----NIDPYIYTPFGSGPRNC 443
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 65.7 bits (153), Expect = 3e-10
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK----------RYFRACLKEALRL 341
+ S V + +++ LA + VQ K+++EI T N Y + E LRL
Sbjct: 307 YETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V R +D + G +IPKG+ V+ P+ L K++ +PE+F+PER+ + D
Sbjct: 367 FPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 65.7 bits (153), Expect = 3e-10
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK----------RYFRACLKEALRL 341
+ S V + +++ LA + VQ K+++EI T N Y + E LRL
Sbjct: 307 YETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V R +D + G +IPKG+ V+ P+ L K++ +PE+F+PER+ + D
Sbjct: 367 FPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 65.7 bits (153), Expect = 3e-10
Identities = 43/141 (30%), Positives = 68/141 (48%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYK----------RYFRACLKEALRL 341
+ S V + +++ LA + VQ K+++EI T N Y + E LRL
Sbjct: 307 YETTSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V R +D + G +IPKG+ V+ P+ L K++ +PE+F+PER+ + D
Sbjct: 367 FPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P + PFG G R+C
Sbjct: 426 ----NIDPYIYTPFGSGPRNC 442
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 64.5 bits (150), Expect = 8e-10
Identities = 44/141 (31%), Positives = 66/141 (46%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 307 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 367 FPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 425
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P PFG G R+C
Sbjct: 426 ----NIDPYTYTPFGSGPRNC 442
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 64.5 bits (150), Expect = 8e-10
Identities = 44/141 (31%), Positives = 66/141 (46%), Gaps = 15/141 (10%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + +++ LA + VQ KL+EEI N Y + E LRL
Sbjct: 306 YETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRL 365
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+ R +D + G +IPKG V+ P+ L R K++ +PE+F+PER+ + D
Sbjct: 366 FPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKD- 424
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
N P PFG G R+C
Sbjct: 425 ----NIDPYTYTPFGSGPRNC 441
>AJ431381-1|CAD24089.1| 186|Homo sapiens steroid
11-beta-hydroxylase protein.
Length = 186
Score = 62.9 bits (146), Expect = 2e-09
Identities = 52/190 (27%), Positives = 95/190 (50%), Gaps = 11/190 (5%)
Query: 78 GPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELE--LT 135
GPEWR R ++NP +L P V+ + P +D +A+DF Q L + +A +++ +
Sbjct: 2 GPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIF 61
Query: 136 KFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTYKLEIRP-SPWRYIATP 194
+++EA+ L G RLG + S S + + + +F+ T +L P S R+ +
Sbjct: 62 HYTIEASNLALFGERLGLVGHSPSS--ASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPK 119
Query: 195 AYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPEEEKSVLEKLIAIDE--KVAVMMAS 252
+K EA+D ++ S N +K ++ + P++ S++ +L+ E A+ S
Sbjct: 120 VWKEHFEAWDCIFQYS---DNCIQKIYQELAFSRPQQYTSIVAELLLNAELSPDAIKANS 176
Query: 253 EMLLAG-IDT 261
L AG +DT
Sbjct: 177 MELTAGSVDT 186
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 62.5 bits (145), Expect = 3e-09
Identities = 34/94 (36%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 329 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
RY +KE LRL VP R D V GY + KG + + L R +++P PEE
Sbjct: 379 RYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEE 438
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+ E + HP +PF G R+C
Sbjct: 439 FQPERFFPENAQ-----GRHPYAYVPFSAGPRNC 467
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 62.5 bits (145), Expect = 3e-09
Identities = 34/94 (36%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 329 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
RY +KE LRL VP R D V GY + KG + + L R +++P PEE
Sbjct: 379 RYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEE 438
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+ E + HP +PF G R+C
Sbjct: 439 FQPERFFPENAQ-----GRHPYAYVPFSAGPRNC 467
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 62.5 bits (145), Expect = 3e-09
Identities = 34/94 (36%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 329 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
RY +KE LRL VP R D V GY + KG + + L R +++P PEE
Sbjct: 357 RYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEE 416
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+ E + HP +PF G R+C
Sbjct: 417 FQPERFFPENAQ-----GRHPYAYVPFSAGPRNC 445
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 62.5 bits (145), Expect = 3e-09
Identities = 34/94 (36%), Positives = 45/94 (47%), Gaps = 5/94 (5%)
Query: 329 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
RY +KE LRL VP R D V GY + KG + + L R +++P PEE
Sbjct: 379 RYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPEE 438
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+ E + HP +PF G R+C
Sbjct: 439 FQPERFFPENAQ-----GRHPYAYVPFSAGPRNC 467
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 61.7 bits (143), Expect = 5e-09
Identities = 55/262 (20%), Positives = 120/262 (45%), Gaps = 26/262 (9%)
Query: 11 KFGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLR----PGFQVLDYYRTQLRKSR 66
K+GP+ + +++ +P+ ++++E NP R P YY+ +
Sbjct: 84 KYGPIYREK--LGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPI---- 137
Query: 67 YGGLHGLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITH--DDA 124
G++ + W++ R +N ++ P+ K + P +D +++DFV L +
Sbjct: 138 -----GVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSG 192
Query: 125 YIKDNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTY-KLEI 183
+ +L +F+ E+ V G R G L++ ++ + A+R + + +F + L +
Sbjct: 193 NYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPE--AQRFIDAIYQMFHTSVPMLNL 250
Query: 184 RPSPWRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPEEEKSVLEKLIAID 243
P +R T +K + A+D + + +Y + +L Q+G + + + +L +L+ D
Sbjct: 251 PPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKG-SVHHDYRGILYRLLG-D 308
Query: 244 EKVAV----MMASEMLLAGIDT 261
K++ +EML G+DT
Sbjct: 309 SKMSFEDIKANVTEMLAGGVDT 330
Score = 54.0 bits (124), Expect = 1e-06
Identities = 43/131 (32%), Positives = 59/131 (45%), Gaps = 18/131 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLRHVVPANLRR- 351
L+ +A N KVQD LR E+ + + +A +KE LRL H + L+R
Sbjct: 339 LYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRL-HPISVTLQRY 397
Query: 352 THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLV 411
D ++ Y IP V L R F+ PE F P RWL + + Y+ N
Sbjct: 398 LVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRN----- 452
Query: 412 TLPFGFGVRSC 422
L FG+GVR C
Sbjct: 453 -LGFGWGVRQC 462
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 60.9 bits (141), Expect = 1e-08
Identities = 55/262 (20%), Positives = 120/262 (45%), Gaps = 26/262 (9%)
Query: 11 KFGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLR----PGFQVLDYYRTQLRKSR 66
K+GP+ + +++ +P+ ++++E NP R P YY+ +
Sbjct: 84 KYGPIYREK--LGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPI---- 137
Query: 67 YGGLHGLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITH--DDA 124
G++ + W++ R +N ++ P+ K + P +D +++DFV L +
Sbjct: 138 -----GVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSG 192
Query: 125 YIKDNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTY-KLEI 183
+ +L +F+ E+ V G R G L++ ++ + A+R + + +F + L +
Sbjct: 193 NYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPE--AQRFIDAIYQMFHTSVPMLNL 250
Query: 184 RPSPWRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPEEEKSVLEKLIAID 243
P +R T +K + A+D + + +Y + +L Q+G + + + +L +L+ D
Sbjct: 251 PPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKG-SVHHDYRGMLYRLLG-D 308
Query: 244 EKVAV----MMASEMLLAGIDT 261
K++ +EML G+DT
Sbjct: 309 SKMSFEDIKANVTEMLAGGVDT 330
Score = 54.0 bits (124), Expect = 1e-06
Identities = 43/131 (32%), Positives = 59/131 (45%), Gaps = 18/131 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLRHVVPANLRR- 351
L+ +A N KVQD LR E+ + + +A +KE LRL H + L+R
Sbjct: 339 LYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRL-HPISVTLQRY 397
Query: 352 THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLV 411
D ++ Y IP V L R F+ PE F P RWL + + Y+ N
Sbjct: 398 LVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRN----- 452
Query: 412 TLPFGFGVRSC 422
L FG+GVR C
Sbjct: 453 -LGFGWGVRQC 462
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 60.5 bits (140), Expect = 1e-08
Identities = 55/262 (20%), Positives = 119/262 (45%), Gaps = 26/262 (9%)
Query: 11 KFGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLR----PGFQVLDYYRTQLRKSR 66
K+GP+ + +++ +P+ ++++E NP R P YY+ +
Sbjct: 84 KYGPIYREK--LGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPI---- 137
Query: 67 YGGLHGLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRLSQITH--DDA 124
G++ + W++ R +N ++ P+ K + P +D +++DFV L +
Sbjct: 138 -----GVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSG 192
Query: 125 YIKDNFELELTKFSLEATALVALGSRLGCLKDSLDSDHPARRLMKSTRDIFELTY-KLEI 183
+ +L +F+ E+ V G R G L++ ++ + A+R + + +F + L +
Sbjct: 193 NYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPE--AQRFIDAIYQMFHTSVPMLNL 250
Query: 184 RPSPWRYIATPAYKMVIEAYDTQWEISMMYINHARKKLEQRGYDIPEEEKSVLEKLIAID 243
P +R T +K + A+D + +Y + +L Q+G + + + +L +L+ D
Sbjct: 251 PPDLFRLFRTKTWKDHVAAWDVILSKADIYTQNFYWELRQKG-SVHHDYRGILYRLLG-D 308
Query: 244 EKVAV----MMASEMLLAGIDT 261
K++ +EML G+DT
Sbjct: 309 SKMSFEDIKANVTEMLAGGVDT 330
Score = 54.0 bits (124), Expect = 1e-06
Identities = 43/131 (32%), Positives = 59/131 (45%), Gaps = 18/131 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLRHVVPANLRR- 351
L+ +A N KVQD LR E+ + + +A +KE LRL H + L+R
Sbjct: 339 LYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRL-HPISVTLQRY 397
Query: 352 THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLV 411
D ++ Y IP V L R F+ PE F P RWL + + Y+ N
Sbjct: 398 LVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRN----- 452
Query: 412 TLPFGFGVRSC 422
L FG+GVR C
Sbjct: 453 -LGFGWGVRQC 462
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 60.5 bits (140), Expect = 1e-08
Identities = 43/142 (30%), Positives = 65/142 (45%), Gaps = 15/142 (10%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI +N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER+ + D
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKD 425
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 426 SIDLYR-----YIPFGAGPRNC 442
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxylase
protein.
Length = 256
Score = 60.1 bits (139), Expect = 2e-08
Identities = 44/130 (33%), Positives = 59/130 (45%), Gaps = 16/130 (12%)
Query: 303 LFNLAMNQKVQDKLREEIRTSESNYKRY----------FRACLKEALRLRHVVPANLRRT 352
LF LA N VQ LR+E ++ + RA LKE LRL V R
Sbjct: 117 LFELARNPNVQQPLRQESLAPAASISEHPQKATTELPLLRAALKETLRLYPVGLILERVV 176
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ Y+IP G V L R+ +P+PE + P+RWL K G+
Sbjct: 177 SSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIK------GSGRNFYH 230
Query: 413 LPFGFGVRSC 422
+PFGFG+R C
Sbjct: 231 VPFGFGMRQC 240
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 60.1 bits (139), Expect = 2e-08
Identities = 52/142 (36%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI-------RT---SESNYKRYFRACLKEALRLR 342
T S V +L F L N +V+ KL EEI RT S+ N A ++E LRLR
Sbjct: 306 TTTSVVKWTLAF-LLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLR 364
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V P + + + D +G + + KG +VI L +EK + QP++F+PER+L +P
Sbjct: 365 PVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFL----NP 420
Query: 402 LYYGNAHPLVT-LPFGFGVRSC 422
P V+ LPFG G RSC
Sbjct: 421 AGTQLISPSVSYLPFGAGPRSC 442
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 59.7 bits (138), Expect = 2e-08
Identities = 44/141 (31%), Positives = 63/141 (44%), Gaps = 16/141 (11%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + L+ LA + VQ KL++EI N Y + E LRL
Sbjct: 307 YETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V R +D + G +IPKG V+ P L K++ +PEEF PER+ +K
Sbjct: 367 FPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD-- 424
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ P + PFG G R+C
Sbjct: 425 ----SIDPYIYTPFGTGPRNC 441
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/142 (30%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 196 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 255
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER+ + D
Sbjct: 256 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKD 315
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 316 SIDLYR-----YIPFGAGPRNC 332
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 59.7 bits (138), Expect = 2e-08
Identities = 44/141 (31%), Positives = 63/141 (44%), Gaps = 16/141 (11%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + L+ LA + VQ KL++EI N Y + E LRL
Sbjct: 307 YETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V R +D + G +IPKG V+ P L K++ +PEEF PER+ +K
Sbjct: 367 FPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD-- 424
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ P + PFG G R+C
Sbjct: 425 ----SIDPYIYTPFGTGPRNC 441
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/142 (30%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER+ + D
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKD 425
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 426 SIDLYR-----YIPFGAGPRNC 442
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/142 (30%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER+ + D
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKD 425
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 426 SIDLYR-----YIPFGAGPRNC 442
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/142 (30%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER+ + D
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKD 425
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 426 SIDLYR-----YIPFGAGPRNC 442
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/142 (30%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER+ + D
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKD 425
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 426 SIDLYR-----YIPFGAGPRNC 442
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 59.7 bits (138), Expect = 2e-08
Identities = 43/142 (30%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER+ + D
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKD 425
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 426 SIDLYR-----YIPFGAGPRNC 442
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 59.7 bits (138), Expect = 2e-08
Identities = 44/141 (31%), Positives = 63/141 (44%), Gaps = 16/141 (11%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + L+ LA + VQ KL++EI N Y + E LRL
Sbjct: 307 YETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V R +D + G +IPKG V+ P L K++ +PEEF PER+ +K
Sbjct: 367 FPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD-- 424
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ P + PFG G R+C
Sbjct: 425 ----SIDPYIYTPFGTGPRNC 441
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 59.3 bits (137), Expect = 3e-08
Identities = 44/141 (31%), Positives = 63/141 (44%), Gaps = 16/141 (11%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALRL 341
+ S V + L+ LA + VQ KL++EI N Y + E LRL
Sbjct: 307 YETTSSVLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRL 366
Query: 342 RHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
V R +D + G +IPKG V+ P L K++ +PEEF PER+ +K
Sbjct: 367 FPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERFSKKKD-- 424
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ P + PFG G R+C
Sbjct: 425 ----SIDPYIYTPFGTGPRNC 441
>AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 58.0 bits (134), Expect = 7e-08
Identities = 38/115 (33%), Positives = 56/115 (48%), Gaps = 11/115 (9%)
Query: 292 FTQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRL 341
F V+ T+ L L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 319 FDTVTTATSWSLMYLVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRH 378
Query: 342 RHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V + +K + P EF+PER+L
Sbjct: 379 SSFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQIDHDQKLWVNPSEFLPERFL 433
>X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein.
Length = 512
Score = 57.6 bits (133), Expect = 9e-08
Identities = 37/114 (32%), Positives = 60/114 (52%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
+VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 380 SLVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 433
>X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein.
Length = 512
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 380 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 433
>M12079-1|AAA52152.1| 191|Homo sapiens POR protein.
Length = 191
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 27 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 85
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 86 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 139
>K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein.
Length = 512
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 380 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 433
>EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 380 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 433
>BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 protein.
Length = 512
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 380 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 433
>AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1
variant protein.
Length = 484
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 293 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 351
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 352 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 405
>AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1
protein.
Length = 251
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 60 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 118
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 119 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 172
>AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1
protein.
Length = 175
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 60 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 118
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 119 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 172
>AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 1 variant protein.
Length = 512
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 380 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 433
>AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein.
Length = 512
Score = 56.8 bits (131), Expect = 2e-07
Identities = 37/114 (32%), Positives = 59/114 (51%), Gaps = 12/114 (10%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
VP + T RD + G+YIPKG V ++ +K + P EF+PER+L
Sbjct: 380 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNPSEFLPERFL 433
>BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 55.6 bits (128), Expect = 4e-07
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 30 LFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVN 89
L P E +YR E A P R + YR RK YG L+ +G +W+ R+
Sbjct: 109 LGSPCLLEALYRTESAYPQRLEIKPWKAYR-DYRKEGYG----LLILEGEDWQRVRSAFQ 163
Query: 90 PALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELELTKFSLEATALVALGS 149
L+ P V I+E+ DF+ R+ ++ + +++D + EL K+S E+ LV
Sbjct: 164 KKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYS-ELNKWSFESICLVLYEK 222
Query: 150 RLGCLK 155
R G L+
Sbjct: 223 RFGLLQ 228
Score = 48.8 bits (111), Expect = 4e-05
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 10/76 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYKR--------YFRACLKEALRLRHVVPANLRR 351
+L+NL+ N +VQ KL +EI++ E+ R Y +ACLKE++RL VP R
Sbjct: 338 ILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRT 397
Query: 352 THRDHIVGGYYIPKGI 367
+ ++G Y +PKGI
Sbjct: 398 LDKATVLGEYALPKGI 413
>BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein.
Length = 448
Score = 55.6 bits (128), Expect = 4e-07
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 30 LFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVN 89
L P E +YR E A P R + YR RK YG L+ +G +W+ R+
Sbjct: 109 LGSPCLLEALYRTESAYPQRLEIKPWKAYR-DYRKEGYG----LLILEGEDWQRVRSAFQ 163
Query: 90 PALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELELTKFSLEATALVALGS 149
L+ P V I+E+ DF+ R+ ++ + +++D + EL K+S E+ LV
Sbjct: 164 KKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYS-ELNKWSFESICLVLYEK 222
Query: 150 RLGCLK 155
R G L+
Sbjct: 223 RFGLLQ 228
Score = 48.8 bits (111), Expect = 4e-05
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 10/76 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYKR--------YFRACLKEALRLRHVVPANLRR 351
+L+NL+ N +VQ KL +EI++ E+ R Y +ACLKE++RL VP R
Sbjct: 338 ILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRT 397
Query: 352 THRDHIVGGYYIPKGI 367
+ ++G Y +PKGI
Sbjct: 398 LDKATVLGEYALPKGI 413
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 55.6 bits (128), Expect = 4e-07
Identities = 36/94 (38%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A L E LR ++VP + T D +V GY IPKG VI + EK++ PE
Sbjct: 360 YTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEV 419
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+L Y+ LV PF G R C
Sbjct: 420 FHPERFLDSSG---YFAKKEALV--PFSLGRRHC 448
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 55.6 bits (128), Expect = 4e-07
Identities = 36/94 (38%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A L E LR ++VP + T D +V GY IPKG VI + EK++ PE
Sbjct: 360 YTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEV 419
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+L Y+ LV PF G R C
Sbjct: 420 FHPERFLDSSG---YFAKKEALV--PFSLGRRHC 448
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 55.6 bits (128), Expect = 4e-07
Identities = 36/94 (38%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A L E LR ++VP + T D +V GY IPKG VI + EK++ PE
Sbjct: 360 YTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEV 419
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+L Y+ LV PF G R C
Sbjct: 420 FHPERFLDSSG---YFAKKEALV--PFSLGRRHC 448
>AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 448
Score = 55.6 bits (128), Expect = 4e-07
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Query: 30 LFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLHGLINAQGPEWREFRTKVN 89
L P E +YR E A P R + YR RK YG L+ +G +W+ R+
Sbjct: 109 LGSPCLLEALYRTESAYPQRLEIKPWKAYR-DYRKEGYG----LLILEGEDWQRVRSAFQ 163
Query: 90 PALLLPKLVKLYAPGIDEIAQDFVQRLSQITHDDAYIKDNFELELTKFSLEATALVALGS 149
L+ P V I+E+ DF+ R+ ++ + +++D + EL K+S E+ LV
Sbjct: 164 KKLMKPGEVMKLDNKINEVLADFMGRIDELCDERGHVEDLYS-ELNKWSFESICLVLYEK 222
Query: 150 RLGCLK 155
R G L+
Sbjct: 223 RFGLLQ 228
Score = 48.8 bits (111), Expect = 4e-05
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 10/76 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYKR--------YFRACLKEALRLRHVVPANLRR 351
+L+NL+ N +VQ KL +EI++ E+ R Y +ACLKE++RL VP R
Sbjct: 338 ILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKESMRLTPSVPFTTRT 397
Query: 352 THRDHIVGGYYIPKGI 367
+ ++G Y +PKGI
Sbjct: 398 LDKATVLGEYALPKGI 413
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 55.6 bits (128), Expect = 4e-07
Identities = 42/142 (29%), Positives = 63/142 (44%), Gaps = 14/142 (9%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PE +K+
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNK 425
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 426 ----DSIDLYRYIPFGAGPRNC 443
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 55.6 bits (128), Expect = 4e-07
Identities = 42/142 (29%), Positives = 63/142 (44%), Gaps = 14/142 (9%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSD 400
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PE +K+
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPESRFSKKNK 425
Query: 401 PLYYGNAHPLVTLPFGFGVRSC 422
+ +PFG G R+C
Sbjct: 426 ----DSIDLYRYIPFGAGPRNC 443
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 54.4 bits (125), Expect = 8e-07
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Query: 330 YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEF 389
Y + E LRL V R +D + G +IPKG V+ P L K++ +PEEF
Sbjct: 26 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEF 85
Query: 390 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
PER+ +K + P + PFG G R+C
Sbjct: 86 RPERFSKKKD------SIDPYIYTPFGTGPRNC 112
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 54.4 bits (125), Expect = 8e-07
Identities = 32/93 (34%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Query: 330 YFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEF 389
Y + E LRL V R +D + G +IPKG V+ P L K++ +PEEF
Sbjct: 13 YLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPEEF 72
Query: 390 IPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
PER+ +K + P + PFG G R+C
Sbjct: 73 RPERFSKKKD------SIDPYIYTPFGTGPRNC 99
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 54.0 bits (124), Expect = 1e-06
Identities = 43/131 (32%), Positives = 59/131 (45%), Gaps = 18/131 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLRHVVPANLRR- 351
L+ +A N KVQD LR E+ + + +A +KE LRL H + L+R
Sbjct: 57 LYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRL-HPISVTLQRY 115
Query: 352 THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLV 411
D ++ Y IP V L R F+ PE F P RWL + + Y+ N
Sbjct: 116 LVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRN----- 170
Query: 412 TLPFGFGVRSC 422
L FG+GVR C
Sbjct: 171 -LGFGWGVRQC 180
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 53.6 bits (123), Expect = 1e-06
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 10/113 (8%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 166 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 225
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPER 393
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER
Sbjct: 226 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 278
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 53.6 bits (123), Expect = 1e-06
Identities = 36/113 (31%), Positives = 52/113 (46%), Gaps = 10/113 (8%)
Query: 291 AFTQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----------YKRYFRACLKEALR 340
A+ S +++ LA + VQ KL+EEI N Y + E LR
Sbjct: 306 AYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLR 365
Query: 341 LRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPER 393
L VV R +D + G +IPKG+ V+ P L K++ +PE+F PER
Sbjct: 366 LFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 418
>M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein.
Length = 230
Score = 51.6 bits (118), Expect = 6e-06
Identities = 38/111 (34%), Positives = 57/111 (51%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL +L + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 36 LSWAVVFLLHHLEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLIATIAEVLRLRPVV 95
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 96 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 146
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 51.6 bits (118), Expect = 6e-06
Identities = 45/174 (25%), Positives = 77/174 (44%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + F+ P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLFLHP 481
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 50.4 bits (115), Expect = 1e-05
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK + R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + + C+KE+LRL VP R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAMWPDPEVYDPFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 50.0 bits (114), Expect = 2e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + + C+KE+LRL VP R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAMWPDPEVYDPFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + + C+KE+LRL VP R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + + C+KE+LRL VP R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + + C+KE+LRL VP R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + + C+KE+LRL VP R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 49.6 bits (113), Expect = 2e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + + C+KE+LRL VP R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 49.2 bits (112), Expect = 3e-05
Identities = 41/128 (32%), Positives = 63/128 (49%), Gaps = 12/128 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLV--EKSDPL 402
P L RT R + GY IP+G +I + E + +P EF P+R+L + S L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRAL 419
Query: 403 YYGNAHPL 410
+G P+
Sbjct: 420 AFGCGAPV 427
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 48.8 bits (111), Expect = 4e-05
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + C+KE+LRL VPA R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 464
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 270 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 329
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 330 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 380
>BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 48.8 bits (111), Expect = 4e-05
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 302 LLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA+N + Q++ REE+R + Y C+KE RL VP+ R
Sbjct: 328 ILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRD 387
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ G +P GI V+ L + + P+ F P R+ E SD HP
Sbjct: 388 LSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD-----QRHPY 442
Query: 411 VTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKVTWNGPPIKIVNKLTNTFVKPYNFTF 470
LPF G R+C F+VT P + + + +KP N +
Sbjct: 443 AYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTRPLTFPNHFILKPKNGMY 500
Query: 471 TSVK 474
+K
Sbjct: 501 LHLK 504
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 48.8 bits (111), Expect = 4e-05
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + C+KE+LRL VPA R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 48.8 bits (111), Expect = 4e-05
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 302 LLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA+N + Q++ REE+R + Y C+KE RL VP+ R
Sbjct: 328 ILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRD 387
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ G +P GI V+ L + + P+ F P R+ E SD HP
Sbjct: 388 LSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD-----QRHPY 442
Query: 411 VTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKVTWNGPPIKIVNKLTNTFVKPYNFTF 470
LPF G R+C F+VT P + + + +KP N +
Sbjct: 443 AYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTRPLTFPNHFILKPKNGMY 500
Query: 471 TSVK 474
+K
Sbjct: 501 LHLK 504
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGTHLDETVWERPHEFWPDRFL 410
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 48.8 bits (111), Expect = 4e-05
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 302 LLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA+N + Q++ REE+R + Y C+KE RL VP+ R
Sbjct: 328 ILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRD 387
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ G +P GI V+ L + + P+ F P R+ E SD HP
Sbjct: 388 LSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD-----QRHPY 442
Query: 411 VTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKVTWNGPPIKIVNKLTNTFVKPYNFTF 470
LPF G R+C F+VT P + + + +KP N +
Sbjct: 443 AYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTRPLTFPNHFILKPKNGMY 500
Query: 471 TSVK 474
+K
Sbjct: 501 LHLK 504
>AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 271 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 330
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 331 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 381
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 271 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 330
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 331 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 381
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 271 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 330
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 331 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 381
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 48.8 bits (111), Expect = 4e-05
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 302 LLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA+N + Q++ REE+R + Y C+KE RL VP+ R
Sbjct: 328 ILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRD 387
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ G +P GI V+ L + + P+ F P R+ E SD HP
Sbjct: 388 LSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD-----QRHPY 442
Query: 411 VTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKVTWNGPPIKIVNKLTNTFVKPYNFTF 470
LPF G R+C F+VT P + + + +KP N +
Sbjct: 443 AYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTRPLTFPNHFILKPKNGMY 500
Query: 471 TSVK 474
+K
Sbjct: 501 LHLK 504
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 48.8 bits (111), Expect = 4e-05
Identities = 41/138 (29%), Positives = 63/138 (45%), Gaps = 20/138 (14%)
Query: 300 TSLLFNLAMNQKVQDKLREEIRTS----ESNYK-----------RYFRACLKEALRLRHV 344
TSL+ L + V K+REE+++ +SN +Y +KE LRL
Sbjct: 241 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 300
Query: 345 VPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYY 404
VP R + + GY IPKG +VI + + EEF P+R+++ +
Sbjct: 301 VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPE---- 356
Query: 405 GNAHPLVTLPFGFGVRSC 422
+A +PFG G+RSC
Sbjct: 357 -DASRFSFIPFGGGLRSC 373
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 48.8 bits (111), Expect = 4e-05
Identities = 41/138 (29%), Positives = 63/138 (45%), Gaps = 20/138 (14%)
Query: 300 TSLLFNLAMNQKVQDKLREEIRTS----ESNYK-----------RYFRACLKEALRLRHV 344
TSL+ L + V K+REE+++ +SN +Y +KE LRL
Sbjct: 310 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 369
Query: 345 VPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYY 404
VP R + + GY IPKG +VI + + EEF P+R+++ +
Sbjct: 370 VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPE---- 425
Query: 405 GNAHPLVTLPFGFGVRSC 422
+A +PFG G+RSC
Sbjct: 426 -DASRFSFIPFGGGLRSC 442
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 48.8 bits (111), Expect = 4e-05
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 302 LLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA+N + Q++ REE+R + Y C+KE RL VP+ R
Sbjct: 327 ILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRD 386
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ G +P GI V+ L + + P+ F P R+ E SD HP
Sbjct: 387 LSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD-----QRHPY 441
Query: 411 VTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKVTWNGPPIKIVNKLTNTFVKPYNFTF 470
LPF G R+C F+VT P + + + +KP N +
Sbjct: 442 AYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTRPLTFPNHFILKPKNGMY 499
Query: 471 TSVK 474
+K
Sbjct: 500 LHLK 503
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 48.8 bits (111), Expect = 4e-05
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 302 LLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA+N + Q++ REE+R + Y C+KE RL VP+ R
Sbjct: 328 ILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRD 387
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ G +P GI V+ L + + P+ F P R+ E SD HP
Sbjct: 388 LSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD-----QRHPY 442
Query: 411 VTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKVTWNGPPIKIVNKLTNTFVKPYNFTF 470
LPF G R+C F+VT P + + + +KP N +
Sbjct: 443 AYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTRPLTFPNHFILKPKNGMY 500
Query: 471 TSVK 474
+K
Sbjct: 501 LHLK 504
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 48.8 bits (111), Expect = 4e-05
Identities = 47/184 (25%), Positives = 72/184 (39%), Gaps = 18/184 (9%)
Query: 302 LLFNLAMNQKVQDKLREEIR----------TSESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA+N + Q++ REE+R + Y C+KE RL VP+ R
Sbjct: 263 ILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRD 322
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ G +P GI V+ L + + P+ F P R+ E SD HP
Sbjct: 323 LSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD-----QRHPY 377
Query: 411 VTLPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKVTWNGPPIKIVNKLTNTFVKPYNFTF 470
LPF G R+C F+VT P + + + +KP N +
Sbjct: 378 AYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVT--PDPTRPLTFPNHFILKPKNGMY 435
Query: 471 TSVK 474
+K
Sbjct: 436 LHLK 439
>AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens
cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
Length = 465
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 271 LSWAAVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 330
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 331 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 381
>AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 403
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 209 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 268
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 269 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 319
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 48.8 bits (111), Expect = 4e-05
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + C+KE+LRL VPA R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 48.8 bits (111), Expect = 4e-05
Identities = 37/111 (33%), Positives = 56/111 (50%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 301 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 360
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 361 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 411
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 48.8 bits (111), Expect = 4e-05
Identities = 41/138 (29%), Positives = 63/138 (45%), Gaps = 20/138 (14%)
Query: 300 TSLLFNLAMNQKVQDKLREEIRTS----ESNYK-----------RYFRACLKEALRLRHV 344
TSL+ L + V K+REE+++ +SN +Y +KE LRL
Sbjct: 310 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 369
Query: 345 VPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYY 404
VP R + + GY IPKG +VI + + EEF P+R+++ +
Sbjct: 370 VPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDRFMLPHPE---- 425
Query: 405 GNAHPLVTLPFGFGVRSC 422
+A +PFG G+RSC
Sbjct: 426 -DASRFSFIPFGGGLRSC 442
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 48.8 bits (111), Expect = 4e-05
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + C+KE+LRL VPA R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 48.8 bits (111), Expect = 4e-05
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + C+KE+LRL VPA R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPKNIKERSPLAFIPFSAGPRNC 468
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 481
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 481
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 48.4 bits (110), Expect = 5e-05
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + + C+KE+LR+ VP R +D ++ G IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVISRHVTQDIVLPDGRVIPKG 417
Query: 367 IDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
I + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 418 IICLISVFGTHHNPAVWPDPEVYDPFRF-----DPENIKERSPLAFIPFSAGPRNC 468
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 481
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 234 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 293
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 294 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 344
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 345 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 397
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 481
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 234 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 293
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 294 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 344
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 345 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 397
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 481
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 48.4 bits (110), Expect = 5e-05
Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANL-RR 351
L +++N VQ+K+ EEI ++ Y A + E RL VVP +
Sbjct: 365 LLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHM 424
Query: 352 THRDHIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
T + ++ GY IPKG +I PN + + R + +PE+F P R+L ++ +
Sbjct: 425 TSENTVLQGYTIPKGT-LILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLI-----KKE 478
Query: 411 VTLPFGFGVRSC 422
+PFG G R C
Sbjct: 479 TFIPFGIGKRVC 490
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 481
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 481
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 20/174 (11%)
Query: 302 LLFNLAMNQKVQDKLREEIRT--SESNYK-------RYFRACLKEALRLRHVVPANLRRT 352
+LF +A + V++ + +EI+T E + K + + E++R + VV +R+
Sbjct: 318 MLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQPVVDLVMRKA 377
Query: 353 HRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVT 412
D ++ GY + KG ++I + R E F+P+P EF E + K+ P Y
Sbjct: 378 LEDDVIDGYPVKKGTNIILNIGRMHRLE-FFPKPNEFTLENFA--KNVPYRYFQ------ 428
Query: 413 LPFGFGVRSCXXXXXXXXXXXXXXXXXXXXFKV-TWNGPPIKIVNKLTNTFVKP 465
PFGFG R C F V T G ++ + K+ + + P
Sbjct: 429 -PFGFGPRGCAGKYIAMVMMKAILVTLLRRFHVKTLQGQCVESIQKIHDLSLHP 481
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 48.4 bits (110), Expect = 5e-05
Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANL-RR 351
L +++N VQ+K+ EEI ++ Y A + E RL VVP +
Sbjct: 365 LLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHM 424
Query: 352 THRDHIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
T + ++ GY IPKG +I PN + + R + +PE+F P R+L ++ +
Sbjct: 425 TSENTVLQGYTIPKGT-LILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLI-----KKE 478
Query: 411 VTLPFGFGVRSC 422
+PFG G R C
Sbjct: 479 TFIPFGIGKRVC 490
>AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein.
Length = 522
Score = 47.6 bits (108), Expect = 9e-05
Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 329 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
RY +KE LRL V R R + GY IPKG V+ + Y P E
Sbjct: 367 RYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPE 426
Query: 389 -FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+ + D G + L +PFG G RSC
Sbjct: 427 GFDPERFGAAREDS--RGASSRLHYIPFGGGARSC 459
>BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 47.2 bits (107), Expect = 1e-04
Identities = 29/84 (34%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A ++E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 349 YMDAVVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 408
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 409 FKPEHFLNENGKFKYSDYFKPFST 432
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 47.2 bits (107), Expect = 1e-04
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ L + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLFHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L RT R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 46.0 bits (104), Expect = 3e-04
Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + Y C+KEALRL VP R
Sbjct: 17 ILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGISRE 76
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 77 LSTPVTFPDGRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ-------HSH 129
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 130 AFLPFSGGSRNC 141
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 411 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 305 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 364
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 365 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 393
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 346 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 405
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 406 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 434
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 46.0 bits (104), Expect = 3e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 46.0 bits (104), Expect = 3e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 411 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrome
P450IIE1 (ethanol-inducible) gene, complete cds. ).
Length = 493
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 349 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 408
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 409 FKPEHFLNENGKFKYSDYFKPFST 432
>J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrome
P-450j mRNA, complete cds. ).
Length = 493
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 349 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 408
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 409 FKPEHFLNENGKFKYSDYFKPFST 432
>DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 349 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 408
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 409 FKPEHFLNENGKFKYSDYFKPFST 432
>DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1
protein.
Length = 493
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 349 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 408
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 409 FKPEHFLNENGKFKYSDYFKPFST 432
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 411 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 411 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 411 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 411 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 349 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 408
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 409 FKPEHFLNENGKFKYSDYFKPFST 432
>BC001776-1|AAH01776.1| 217|Homo sapiens CYP27B1 protein protein.
Length = 217
Score = 46.0 bits (104), Expect = 3e-04
Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 12/151 (7%)
Query: 12 FGPLVKVDGVFARGTMLFLFEPDHFEQVYRAEEANPLRPGFQVLDYYRTQLRKSRYGGLH 71
FGP+ F +++ P E++ R E P R F T+ R+ R
Sbjct: 72 FGPVWLAS--FGTVRTVYVAAPALVEELLRQEGPRPERCSFSPW----TEHRRCRQRAC- 124
Query: 72 GLINAQGPEWREFRTKVNPALLLPKLVKLYAPGIDEIAQDFVQRL----SQITHDDAYIK 127
GL+ A+G EW+ R+ + P LL P+ YA ++ + D V+RL + T A ++
Sbjct: 125 GLLTAEGEEWQRLRSLLAPLLLRPQAAARYAGTLNNVVCDLVRRLRRQRGRGTGPPALVR 184
Query: 128 DNFELELTKFSLEATALVALGSRLGCLKDSL 158
D E KF LE + G G SL
Sbjct: 185 D-VAGEFYKFGLEGESQDRAGQASGAPYQSL 214
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 46.0 bits (104), Expect = 3e-04
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 10/111 (9%)
Query: 295 VSFVTTSLLFNLAMNQKVQDKLREEIRTSESN----YKRYFR-----ACLKEALRLRHVV 345
+S+ LL + + Q++Q++L E+ S+ YK R A + E LRLR VV
Sbjct: 300 LSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVV 359
Query: 346 PANLRR-THRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWL 395
P L T R + GY IP+G +I + E + +P EF P+R+L
Sbjct: 360 PLALPHCTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFL 410
>AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family
26, subfamily C, polypeptide 1 protein.
Length = 522
Score = 46.0 bits (104), Expect = 3e-04
Identities = 33/95 (34%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
Query: 329 RYFRACLKEALRLRHVVPANLRRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
RY +KE LRL V R R + GY IPKG V+ + Y P E
Sbjct: 367 RYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPE 426
Query: 389 -FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F PER+ + D G + +PFG G RSC
Sbjct: 427 GFDPERFGAAREDS--RGASSRFHYIPFGGGARSC 459
>AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 protein.
Length = 493
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 349 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 408
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 409 FKPEHFLNENGKFKYSDYFKPFST 432
>AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P450
2E1 protein.
Length = 97
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 3 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 62
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 63 FKPEHFLNENGKFKYSDYFKPFST 86
>AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1
protein.
Length = 493
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 349 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 408
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 409 FKPEHFLNENGKFKYSDYFKPFST 432
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 46.0 bits (104), Expect = 3e-04
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L EK + + V PF G R+C
Sbjct: 411 FNPQHFLNEKGQ---FKKSDAFV--PFSIGKRNC 439
>AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1
protein.
Length = 462
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 318 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 377
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 378 FKPEHFLNENGKFKYSDYFKPFST 401
>AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 1 variant protein.
Length = 336
Score = 46.0 bits (104), Expect = 3e-04
Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R +VP+NL RD I GY IPKG V+ + + + +P PE+
Sbjct: 245 YMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEK 304
Query: 389 FIPERWLVEKSDPLYYGNAHPLVT 412
F PE +L E Y P T
Sbjct: 305 FKPEHFLNENGKFKYSDYFKPFST 328
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 44.8 bits (101), Expect = 7e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 44.8 bits (101), Expect = 7e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 44.8 bits (101), Expect = 7e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 334 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 393
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 394 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ-------HSH 446
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 447 AFLPFSGGSRNC 458
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 44.8 bits (101), Expect = 7e-04
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 310 QKVQDKLRE----EIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIP 364
Q+VQ+ L++ EI + + C+KE+LRL P R +D ++ G IP
Sbjct: 356 QEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIP 415
Query: 365 KGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
KGI + + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 416 KGITCLIDIIGVHHNPTVWPDPEVYDPFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 44.8 bits (101), Expect = 7e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 44.8 bits (101), Expect = 7e-04
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 310 QKVQDKLRE----EIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIP 364
Q+VQ+ L++ EI + + C+KE+LRL P R +D ++ G IP
Sbjct: 356 QEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIP 415
Query: 365 KGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
KGI + + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 416 KGITCLIDIIGVHHNPTVWPDPEVYDPFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 44.8 bits (101), Expect = 7e-04
Identities = 41/132 (31%), Positives = 56/132 (42%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPSRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 44.8 bits (101), Expect = 7e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 44.8 bits (101), Expect = 7e-04
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 310 QKVQDKLRE----EIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIP 364
Q+VQ+ L++ EI + + C+KE+LRL P R +D ++ G IP
Sbjct: 356 QEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIP 415
Query: 365 KGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
KGI + + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 416 KGITCLIDIIGVHHNPTVWPDPEVYDPFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 44.8 bits (101), Expect = 7e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 44.8 bits (101), Expect = 7e-04
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 310 QKVQDKLRE----EIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIP 364
Q+VQ+ L++ EI + + C+KE+LRL P R +D ++ G IP
Sbjct: 290 QEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIP 349
Query: 365 KGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
KGI + + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 350 KGITCLIDIIGVHHNPTVWPDPEVYDPFRF-----DPENSKGRSPLAFIPFSAGPRNC 402
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 44.8 bits (101), Expect = 7e-04
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 310 QKVQDKLRE----EIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIP 364
Q+VQ+ L++ EI + + C+KE+LRL P R +D ++ G IP
Sbjct: 356 QEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIP 415
Query: 365 KGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
KGI + + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 416 KGITCLIDIIGVHHNPTVWPDPEVYDPFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 44.8 bits (101), Expect = 7e-04
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 310 QKVQDKLRE----EIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIP 364
Q+VQ+ L++ EI + + C+KE+LRL P R +D ++ G IP
Sbjct: 356 QEVQELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIP 415
Query: 365 KGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
KGI + + + +P PE + P R+ DP PL +PF G R+C
Sbjct: 416 KGITCLIDIIGVHHNPTVWPDPEVYDPFRF-----DPENSKGRSPLAFIPFSAGPRNC 468
>U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 44.4 bits (100), Expect = 9e-04
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKGI+V + R +F+ P +
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGIEVFPMLGSVLRDLRFFSNPRD 410
Query: 389 FIPERWLVEK 398
F P+ +L EK
Sbjct: 411 FNPQHFLGEK 420
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 44.4 bits (100), Expect = 9e-04
Identities = 41/132 (31%), Positives = 57/132 (43%), Gaps = 18/132 (13%)
Query: 302 LLFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRR 351
+L+ LA + K Q++ REEI + + + Y C+KEALRL VP R
Sbjct: 333 ILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLFPPVPGIGRE 392
Query: 352 THRD-HIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
G +PKGI V+ L + K +P PE F P R+ + H
Sbjct: 393 LSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQ-------HSH 445
Query: 411 VTLPFGFGVRSC 422
LPF G R+C
Sbjct: 446 AFLPFSGGSRNC 457
>M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 44.0 bits (99), Expect = 0.001
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L +K + + V PF G R C
Sbjct: 411 FNPQHFLDDKGQ---FKKSDAFV--PFSIGKRYC 439
>BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 7 protein.
Length = 494
Score = 44.0 bits (99), Expect = 0.001
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 6/94 (6%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R F+ P++
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQD 410
Query: 389 FIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
F P+ +L +K + + V PF G R C
Sbjct: 411 FNPQHFLDDKGQ---FKKSDAFV--PFSIGKRYC 439
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 310 QKVQDKLRE----EIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIP 364
Q+VQ+ L++ EI + + C+KE+LRL VP R +D ++ G IP
Sbjct: 356 QEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIP 415
Query: 365 KGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
KGI + + + +P PE + P R+ E PL +PF G R+C
Sbjct: 416 KGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQEN-----IKERSPLAFIPFSAGPRNC 468
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 44.0 bits (99), Expect = 0.001
Identities = 35/118 (29%), Positives = 54/118 (45%), Gaps = 10/118 (8%)
Query: 310 QKVQDKLRE----EIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIP 364
Q+VQ+ L++ EI + + C+KE+LRL VP R +D ++ G IP
Sbjct: 356 QEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIP 415
Query: 365 KGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
KGI + + + +P PE + P R+ E PL +PF G R+C
Sbjct: 416 KGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQEN-----IKERSPLAFIPFSAGPRNC 468
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 43.2 bits (97), Expect = 0.002
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>M12078-1|AAA52154.1| 192|Homo sapiens POR protein.
Length = 192
Score = 42.7 bits (96), Expect = 0.003
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 13/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 27 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 85
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 86 SFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 145
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ L G G R C
Sbjct: 146 INKPLSEKMMML-VGMGKRRC 165
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 42.7 bits (96), Expect = 0.003
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 14/141 (9%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEIRTSESNYKR----------YFRACLKEALRLR 342
T + ++ SL++ L ++Q K+++E+ T +R Y A + E R
Sbjct: 321 TVTTAISWSLMY-LVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHS 379
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDP 401
+P + T RD + G+YIPK V ++ + + P EF PER+L
Sbjct: 380 PFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTA 439
Query: 402 LYYGNAHPLVTLPFGFGVRSC 422
+ + ++ FG G R C
Sbjct: 440 INKPLSEKMML--FGMGKRRC 458
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 42.7 bits (96), Expect = 0.003
Identities = 32/117 (27%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 308 MNQKVQDKLREEIRTSESNYKRYFRACLKEALRLRHVVPANLRRTHRDHIV-GGYYIPKG 366
+ + ++D+ +EI + + CLKE+LRL +P R +D ++ IPKG
Sbjct: 358 VQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKG 417
Query: 367 IDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRSC 422
+V N + + + +P PE + P R+ DP P+ +PF G R+C
Sbjct: 418 -NVCNINIFAIHHNPSVWPDPEVYDPFRF-----DPENAQKRSPMAFIPFSAGPRNC 468
>AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1
protein.
Length = 144
Score = 42.7 bits (96), Expect = 0.003
Identities = 31/105 (29%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 293 TQVSFVTTSLLFNLAMNQKVQDKLREEI----------RTSESNYKRYFRACLKEALRLR 342
T + ++ SL++ L MN +VQ K++EE+ R S+ ++ Y A + E R
Sbjct: 40 TVTTAISWSLMY-LVMNPRVQRKIQEELDTVIGRSRRPRLSDRSHLPYMEAFILETFRHS 98
Query: 343 HVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQP 386
VP + T RD + G+YIPKG V ++ +K + P
Sbjct: 99 SFVPFTIPHSTTRDTSLKGFYIPKGRCVFVNQWQINHDQKLWVNP 143
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 387
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 388 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 441
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 442 AFMPFSAGPRNC 453
>U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein.
Length = 494
Score = 42.3 bits (95), Expect = 0.004
Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R V+P +L RR +D +++PKG +V + R +F+ P +
Sbjct: 351 YMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDLRFFSNPRD 410
Query: 389 FIPERWLVEK 398
F P+ +L EK
Sbjct: 411 FNPQHFLGEK 420
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 387
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 388 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 441
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 442 AFMPFSAGPRNC 453
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 387
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 388 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 441
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 442 AFMPFSAGPRNC 453
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 388
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 389 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 442
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 443 AFMPFSAGPRNC 454
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 373
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 374 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 427
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 428 AFMPFSAGPRNC 439
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 388
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 389 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 442
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 443 AFMPFSAGPRNC 454
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 387
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 388 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 441
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 442 AFMPFSAGPRNC 453
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 387
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 388 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 441
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 442 AFMPFSAGPRNC 453
>AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 373
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 374 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 427
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 428 AFMPFSAGPRNC 439
>AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 388
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 389 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 442
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 443 AFMPFSAGPRNC 454
>AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 387
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 388 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 441
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 442 AFMPFSAGPRNC 453
>AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 328 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 387
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 388 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 441
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 442 AFMPFSAGPRNC 453
>AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 329 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 388
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 389 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 442
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 443 AFMPFSAGPRNC 454
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 314 LYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 373
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 374 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 427
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 428 AFMPFSAGPRNC 439
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 42.3 bits (95), Expect = 0.004
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 18/132 (13%)
Query: 303 LFNLAMNQKVQDKLREEIRT----------SESNYKRYFRACLKEALRLRHVVPANLRRT 352
L+ +A+ + Q + REE+R + Y C+KE+ RL VP R+
Sbjct: 328 LYCIALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYPPVPQVYRQL 387
Query: 353 HRD-HIVGGYYIPKGIDVIAPNEY-LSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPL 410
+ V G +P G +I+ + Y L R+ +P PE F R+ E + HP
Sbjct: 388 SKPVTFVDGRSLPAG-SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS-----KRHPF 441
Query: 411 VTLPFGFGVRSC 422
+PF G R+C
Sbjct: 442 AFMPFSAGPRNC 453
>AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol
7alpha-hydroxylase protein.
Length = 469
Score = 42.3 bits (95), Expect = 0.004
Identities = 24/81 (29%), Positives = 46/81 (56%), Gaps = 5/81 (6%)
Query: 317 REEIRTSESNYKRYF--RACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPN 373
+++I+ SE + ++ + C+ E +RL+ P + R+ + + Y IP G ++
Sbjct: 312 KDKIKVSEDDLEKLLLIKWCVLETIRLK--APGVITRKVVKPVEILNYIIPSGDLLMLSP 369
Query: 374 EYLSRSEKFYPQPEEFIPERW 394
+L R+ K++P+PE F PERW
Sbjct: 370 FWLHRNPKYFPEPELFKPERW 390
>J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein.
Length = 491
Score = 41.9 bits (94), Expect = 0.005
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 330 YFRACLKEALRLRHVVPANL-RRTHRDHIVGGYYIPKGIDVIAPNEYLSRSEKFYPQPEE 388
Y A + E R ++P NL R RD G+ IPKG DVI + + P+E
Sbjct: 348 YTDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQE 407
Query: 389 FIPERWL 395
F PE +L
Sbjct: 408 FNPEHFL 414
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 41.9 bits (94), Expect = 0.005
Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 14/121 (11%)
Query: 310 QKVQDKLREEIRTSES------NYKRYFRACLKEALRLRHVVPANLRRTHRDHIV--GGY 361
Q+ +D++RE + S + Y C+KE LRL V N+ R I G
Sbjct: 338 QRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPV-VNISRLLDKPITFPDGR 396
Query: 362 YIPKGIDVIAPNEYLSRSEKFYPQPEEFIPERWLVEKSDPLYYGNAHPLVTLPFGFGVRS 421
+P GI V L + F+ P+ F P R+ E S+ + HP +PF G+R+
Sbjct: 397 SLPAGITVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKI-----HPYAFIPFSAGLRN 451
Query: 422 C 422
C
Sbjct: 452 C 452
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.323 0.140 0.422
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 64,611,271
Number of Sequences: 224733
Number of extensions: 2586061
Number of successful extensions: 5278
Number of sequences better than 10.0: 384
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 182
Number of HSP's that attempted gapping in prelim test: 4756
Number of HSP's gapped (non-prelim): 497
length of query: 474
length of database: 73,234,838
effective HSP length: 93
effective length of query: 381
effective length of database: 52,334,669
effective search space: 19939508889
effective search space used: 19939508889
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 67 (31.1 bits)
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