Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005351-TA|BGIBMGA005351-PA|IPR011046|WD40-like,
IPR000219|DH
(1187 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC112926-1|AAI12927.1| 1306|Homo sapiens ARHGEF10 protein protein. 361 8e-99
AB002292-1|BAA20754.2| 1405|Homo sapiens KIAA0294 protein. 361 8e-99
AF009205-1|AAB71662.1| 988|Homo sapiens unknown protein. 360 1e-98
DQ139833-1|AAZ73162.1| 1235|Homo sapiens GrinchGEF protein. 342 5e-93
AL358593-3|CAH74137.1| 1052|Homo sapiens Rho guanine nucleotide ... 338 5e-92
BC117171-1|AAI17172.1| 1240|Homo sapiens Rho guanine nucleotide ... 335 6e-91
AB046846-1|BAB13452.1| 1284|Homo sapiens KIAA1626 protein protein. 335 6e-91
AL358593-2|CAH74136.1| 1240|Homo sapiens Rho guanine nucleotide ... 332 6e-90
AL358593-1|CAH74135.1| 1279|Homo sapiens Rho guanine nucleotide ... 332 6e-90
AL139250-2|CAI22140.1| 1240|Homo sapiens Rho guanine nucleotide ... 332 6e-90
AL139250-1|CAI22139.1| 1279|Homo sapiens Rho guanine nucleotide ... 332 6e-90
BC080596-1|AAH80596.1| 886|Homo sapiens ARHGEF10L protein protein. 257 1e-67
BC036809-1|AAH36809.1| 660|Homo sapiens ARHGEF10 protein protein. 235 5e-61
BC065561-1|AAH65561.1| 832|Homo sapiens ARHGEF10L protein protein. 213 2e-54
BC040474-1|AAH40474.1| 380|Homo sapiens ARHGEF10 protein protein. 181 1e-44
AF378754-1|AAL11991.1| 2063|Homo sapiens tumor endothelial marke... 124 2e-27
AB002335-1|BAA20795.2| 1609|Homo sapiens KIAA0337 protein. 124 2e-27
AK001383-1|BAA91663.1| 596|Homo sapiens protein ( Homo sapiens ... 118 9e-26
AY850123-1|AAX47276.1| 1307|Homo sapiens sperm associated antige... 96 8e-19
AF327452-1|AAN61565.1| 1311|Homo sapiens JNK-associated leucine-... 96 8e-19
AB011088-1|BAA25442.3| 1382|Homo sapiens KIAA0516 protein protein. 96 8e-19
AL031717-1|CAM26394.1| 1336|Homo sapiens mitogen-activated prote... 94 3e-18
AL031710-1|CAM26364.1| 1336|Homo sapiens mitogen-activated prote... 94 3e-18
AB028989-1|BAA83018.2| 1346|Homo sapiens KIAA1066 protein protein. 94 3e-18
DQ847274-1|ABH10140.1| 914|Homo sapiens epithelial cell transfo... 93 4e-18
BC112086-1|AAI12087.1| 883|Homo sapiens epithelial cell transfo... 93 4e-18
AY376439-1|AAQ83675.1| 882|Homo sapiens epithelial cell transfo... 93 4e-18
AY236487-1|AAP74807.1| 766|Homo sapiens proliferation-inducing ... 93 4e-18
AK023267-1|BAB14498.1| 798|Homo sapiens protein ( Homo sapiens ... 93 4e-18
AF542172-1|AAQ11383.1| 508|Homo sapiens HLC-6 protein. 93 4e-18
AK092020-1|BAC03792.1| 633|Homo sapiens protein ( Homo sapiens ... 89 9e-17
X02596-1|CAA26441.1| 1271|Homo sapiens bcr protein. 87 3e-16
U07000-3|AAB60389.1| 889|Homo sapiens breakpoint cluster region... 87 3e-16
U07000-2|AAB60390.1| 936|Homo sapiens breakpoint cluster region... 87 3e-16
U07000-1|AAB60388.1| 1271|Homo sapiens breakpoint cluster region... 87 3e-16
M15025-1|AAA35594.1| 693|Homo sapiens protein ( Human BCR/ABL m... 87 3e-16
AB209991-1|BAE06073.1| 1287|Homo sapiens BCR variant protein pro... 87 3e-16
AE006639-4|AAK61290.1| 1342|Homo sapiens similar to sperm specif... 87 5e-16
U01147-1|AAC50063.1| 859|Homo sapiens guanine nucleotide regula... 85 2e-15
L19704-1|AAC37519.1| 822|Homo sapiens ABR protein. 85 2e-15
Y00661-1|CAA68676.1| 1227|Homo sapiens protein ( Human bcr mRNA ... 84 2e-15
AK126882-1|BAC86734.1| 362|Homo sapiens protein ( Homo sapiens ... 76 7e-13
DQ904331-1|ABI98401.1| 835|Homo sapiens lung specific F-box and... 75 2e-12
AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric ... 64 2e-09
AL031718-1|CAB72318.1| 552|Homo sapiens c371H6.1 (KIAA0516 prot... 63 5e-09
AK057294-1|BAB71413.1| 766|Homo sapiens protein ( Homo sapiens ... 60 4e-08
Z85987-1|CAI42222.1| 961|Homo sapiens FYVE, RhoGEF and PH domai... 60 6e-08
U11690-1|AAA57004.1| 961|Homo sapiens FGD1 protein. 60 6e-08
BC034530-1|AAH34530.1| 961|Homo sapiens FYVE, RhoGEF and PH dom... 60 6e-08
AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology dom... 59 1e-07
AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology dom... 59 1e-07
AL445192-1|CAI39886.1| 1659|Homo sapiens RP11-269H4.1 protein. 58 2e-07
AL133342-1|CAI23274.1| 1659|Homo sapiens RP11-269H4.1 protein. 58 2e-07
AL035106-1|CAI43186.1| 1659|Homo sapiens RP11-269H4.1 protein. 58 2e-07
AJ320261-1|CAC86401.1| 1659|Homo sapiens P-Rex1 protein protein. 58 2e-07
AB037836-1|BAA92653.2| 1621|Homo sapiens KIAA1415 protein protein. 58 2e-07
AK024429-1|BAB15719.1| 1430|Homo sapiens FLJ00018 protein protein. 57 3e-07
BC129953-1|AAI29954.1| 1219|Homo sapiens PLEKHG3 protein protein. 56 6e-07
AF249745-1|AAF79955.1| 720|Homo sapiens RhoGEF protein. 56 6e-07
AC009477-1|AAX93134.1| 547|Homo sapiens unknown protein. 56 6e-07
AB042199-1|BAB11941.1| 619|Homo sapiens APC-stimulated guanine ... 56 6e-07
AB029035-1|BAA83064.1| 694|Homo sapiens KIAA1112 protein protein. 56 6e-07
BC075858-1|AAH75858.1| 1253|Homo sapiens PLEKHG2 protein protein. 56 8e-07
AY508997-1|AAS82572.1| 979|Homo sapiens P-Rex2B protein. 56 1e-06
AY508996-1|AAS82571.1| 1606|Homo sapiens P-Rex2 protein. 56 1e-06
BC032429-1|AAH32429.1| 725|Homo sapiens FGD3 protein protein. 55 1e-06
AK000004-1|BAA92229.1| 698|Homo sapiens FLJ00004 protein protein. 55 1e-06
BC111054-1|AAI11055.1| 725|Homo sapiens FGD3 protein protein. 55 2e-06
AY211386-1|AAP20645.1| 634|Homo sapiens FGD3 protein. 55 2e-06
AL451065-1|CAI95107.1| 725|Homo sapiens FYVE, RhoGEF and PH dom... 55 2e-06
AL389924-2|CAI41118.1| 725|Homo sapiens FYVE, RhoGEF and PH dom... 55 2e-06
AJ437636-1|CAD26885.2| 1606|Homo sapiens P-Rex2 protein protein. 55 2e-06
BX538322-1|CAD98096.1| 1210|Homo sapiens hypothetical protein pr... 54 2e-06
BC125226-1|AAI25227.1| 639|Homo sapiens FGD6 protein protein. 54 2e-06
BC125225-1|AAI25226.1| 639|Homo sapiens FGD6 protein protein. 54 2e-06
AY570973-1|AAS59407.1| 205|Homo sapiens PtdIns(3,4,5)-dependent... 54 2e-06
AK128492-1|BAC87464.1| 1053|Homo sapiens protein ( Homo sapiens ... 54 2e-06
AK124904-1|BAC85990.1| 1430|Homo sapiens protein ( Homo sapiens ... 54 3e-06
D63476-1|BAA09763.2| 802|Homo sapiens KIAA0142 protein. 54 4e-06
BC060776-1|AAH60776.1| 803|Homo sapiens ARHGEF7 protein protein. 54 4e-06
BC050521-1|AAH50521.1| 764|Homo sapiens Rho guanine nucleotide ... 54 4e-06
AL834228-1|CAD38906.1| 812|Homo sapiens hypothetical protein pr... 54 4e-06
AL390754-5|CAM13628.1| 646|Homo sapiens Rho guanine nucleotide ... 54 4e-06
AL390754-4|CAI12463.1| 705|Homo sapiens Rho guanine nucleotide ... 54 4e-06
AL390754-2|CAI12461.1| 625|Homo sapiens Rho guanine nucleotide ... 54 4e-06
AL139086-4|CAM20788.1| 646|Homo sapiens Rho guanine nucleotide ... 54 4e-06
AL139086-3|CAI14672.1| 705|Homo sapiens Rho guanine nucleotide ... 54 4e-06
AL139086-2|CAI14671.1| 625|Homo sapiens Rho guanine nucleotide ... 54 4e-06
AB177849-1|BAD66827.1| 680|Homo sapiens KIAA0142 splice variant... 54 4e-06
AB177848-1|BAD66826.1| 691|Homo sapiens KIAA0142 splice variant... 54 4e-06
AB037783-1|BAA92600.1| 699|Homo sapiens KIAA1362 protein protein. 54 4e-06
BC033905-1|AAH33905.1| 753|Homo sapiens ARHGEF7 protein protein. 53 5e-06
BC057394-1|AAH57394.1| 1562|Homo sapiens Rho guanine nucleotide ... 52 9e-06
BC053655-1|AAH53655.1| 655|Homo sapiens FYVE, RhoGEF and PH dom... 52 9e-06
BC040275-1|AAH40275.1| 1181|Homo sapiens RASGRF1 protein protein. 52 9e-06
BC023645-1|AAH23645.1| 655|Homo sapiens FYVE, RhoGEF and PH dom... 52 9e-06
AL356104-3|CAH72940.1| 1522|Homo sapiens Rho guanine nucleotide ... 52 9e-06
AL356104-2|CAH72939.1| 1562|Homo sapiens Rho guanine nucleotide ... 52 9e-06
AL157713-2|CAH70127.1| 1522|Homo sapiens Rho guanine nucleotide ... 52 9e-06
AL157713-1|CAH70128.1| 1562|Homo sapiens Rho guanine nucleotide ... 52 9e-06
AB002378-1|BAA20834.2| 1539|Homo sapiens KIAA0380 protein protein. 52 9e-06
AY533677-1|AAS57923.1| 257|Homo sapiens BCR protein. 52 2e-05
AJ298916-1|CAC82654.1| 251|Homo sapiens BCR/FGFR1 chimaeric fus... 52 2e-05
AY536245-1|AAS46907.1| 144|Homo sapiens breakpoint cluster regi... 51 2e-05
L26584-1|AAA58417.1| 1275|Homo sapiens CDC25 protein. 51 3e-05
BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein. 51 3e-05
AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein. 51 3e-05
BC045552-1|AAH45552.1| 471|Homo sapiens FGD4 protein protein. 50 5e-05
AF180681-1|AAF36817.1| 1544|Homo sapiens guanine nucleotide exch... 50 5e-05
AB002380-1|BAA20836.2| 1443|Homo sapiens KIAA0382 protein protein. 50 5e-05
BC109291-1|AAI09292.1| 652|Homo sapiens spermatogenesis associa... 49 9e-05
BC109290-1|AAI09291.1| 652|Homo sapiens spermatogenesis associa... 49 9e-05
BC020208-1|AAH20208.1| 984|Homo sapiens MCF.2 cell line derived... 49 9e-05
BC011853-1|AAH11853.1| 984|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL596093-7|CAI39525.1| 984|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL596093-6|CAI94928.1| 1067|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL596093-4|CAI39524.2| 1096|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL596093-3|CAI39523.1| 1137|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL359736-2|CAH72290.2| 574|Homo sapiens spermatogenesis associa... 49 9e-05
AL359736-1|CAH72289.1| 652|Homo sapiens spermatogenesis associa... 49 9e-05
AL356740-10|CAH70245.1| 984|Homo sapiens MCF.2 cell line derive... 49 9e-05
AL356740-8|CAI94923.1| 1067|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL356740-6|CAH70244.2| 1096|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL356740-4|CAH70243.1| 1137|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL162454-4|CAI39871.1| 984|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL162454-3|CAI95103.1| 1067|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL162454-2|CAI39870.2| 1096|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL162454-1|CAI39869.1| 1137|Homo sapiens MCF.2 cell line derived... 49 9e-05
AL137002-20|CAI41392.1| 984|Homo sapiens MCF.2 cell line derive... 49 9e-05
AL137002-18|CAI95400.1| 1067|Homo sapiens MCF.2 cell line derive... 49 9e-05
AL137002-17|CAI41390.2| 1096|Homo sapiens MCF.2 cell line derive... 49 9e-05
AL137002-11|CAI41383.1| 1137|Homo sapiens MCF.2 cell line derive... 49 9e-05
AK160371-1|BAD18714.1| 527|Homo sapiens FLJ00298 protein protein. 49 9e-05
AK055770-1|BAB71009.1| 652|Homo sapiens factor. protein. 49 9e-05
AF118886-1|AAD20348.1| 753|Homo sapiens VAV-3 protein beta isof... 49 9e-05
AB116075-1|BAD08352.1| 904|Homo sapiens Ost-I protein. 49 9e-05
AB116074-1|BAD08351.1| 1067|Homo sapiens Ost-II protein. 49 9e-05
AB002360-1|BAA20817.1| 1108|Homo sapiens KIAA0362 protein. 49 9e-05
U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein. 49 1e-04
AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein. 49 1e-04
AF067817-1|AAC79695.1| 847|Homo sapiens VAV-3 protein protein. 49 1e-04
AB209754-1|BAD92991.1| 2202|Homo sapiens triple functional domai... 49 1e-04
AB115332-1|BAC79392.1| 255|Homo sapiens transforming gene produ... 49 1e-04
BC126112-1|AAI26113.1| 1237|Homo sapiens Ras protein-specific gu... 48 2e-04
AY367054-1|AAQ72372.1| 280|Homo sapiens actin-filament binding ... 48 2e-04
AL591042-2|CAI14458.1| 753|Homo sapiens vav 3 oncogene protein. 48 2e-04
AL591042-1|CAI14457.1| 847|Homo sapiens vav 3 oncogene protein. 48 2e-04
AL513206-2|CAH73196.1| 753|Homo sapiens vav 3 oncogene protein. 48 2e-04
AL513206-1|CAH73195.1| 847|Homo sapiens vav 3 oncogene protein. 48 2e-04
AL391235-1|CAH72458.1| 847|Homo sapiens vav 3 oncogene protein. 48 2e-04
AL353892-1|CAI21786.1| 847|Homo sapiens vav 3 oncogene protein. 48 2e-04
AF181250-1|AAD55268.1| 1237|Homo sapiens Ras guanine nucleotide ... 48 2e-04
AF118887-1|AAD20349.1| 847|Homo sapiens VAV-3 protein protein. 48 2e-04
AF023130-1|AAB80953.1| 1237|Homo sapiens Ras-GRF2 protein. 48 2e-04
BC117406-1|AAI17407.1| 516|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AL451106-3|CAI39552.1| 478|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AL451106-1|CAI39550.1| 516|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AL391277-3|CAI40403.1| 478|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AL391277-2|CAI40402.1| 495|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AL391277-1|CAI40401.1| 516|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AL355142-3|CAI41197.1| 478|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AL355142-2|CAI41196.1| 495|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AL355142-1|CAI41195.1| 516|Homo sapiens Cdc42 guanine nucleotid... 48 2e-04
AB007884-1|BAA24854.2| 567|Homo sapiens KIAA0424 protein. 48 2e-04
AL160264-1|CAI20471.1| 697|Homo sapiens FYVE, RhoGEF and PH dom... 47 4e-04
U02081-1|AAB08847.1| 460|Homo sapiens guanine nucleotide regula... 47 5e-04
BC053553-1|AAH53553.1| 596|Homo sapiens neuroepithelial cell tr... 47 5e-04
BC010285-1|AAH10285.1| 542|Homo sapiens neuroepithelial cell tr... 47 5e-04
AL732437-5|CAI11033.1| 596|Homo sapiens neuroepithelial cell tr... 47 5e-04
AL732437-3|CAI11031.1| 542|Homo sapiens neuroepithelial cell tr... 47 5e-04
AJ010046-1|CAA08974.1| 548|Homo sapiens guanine nucleotide-exch... 47 5e-04
AB209852-1|BAD93089.1| 624|Homo sapiens Neuroepithelial cell tr... 47 5e-04
AB067496-1|BAB67802.2| 1287|Homo sapiens KIAA1909 protein protein. 46 6e-04
BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 doma... 46 8e-04
BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein. 46 8e-04
AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isofor... 46 8e-04
AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form p... 46 0.001
AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein. 44 0.002
AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isof... 44 0.002
AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein. 44 0.002
X12556-1|CAA31069.1| 925|Homo sapiens protein ( Human mRNA for ... 44 0.003
U16296-1|AAA98443.1| 1591|Homo sapiens TIAM1 protein protein. 44 0.003
D25304-1|BAA04985.1| 773|Homo sapiens KIAA0006 protein. 44 0.003
BC043505-1|AAH43505.1| 538|Homo sapiens ARHGEF6 protein protein. 44 0.003
BC039856-1|AAH39856.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 44 0.003
AL683813-1|CAI39443.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 44 0.003
AL161777-3|CAI39715.1| 1070|Homo sapiens MCF.2 cell line derived... 44 0.003
AL135783-5|CAI42903.1| 622|Homo sapiens Rac/Cdc42 guanine nucle... 44 0.003
AL135783-1|CAI42899.1| 776|Homo sapiens Rac/Cdc42 guanine nucle... 44 0.003
AL117234-1|CAB55301.1| 985|Homo sapiens hypothetical protein pr... 44 0.003
AL033403-7|CAA21955.1| 925|Homo sapiens MCF.2 cell line derived... 44 0.003
AL033403-6|CAI42107.1| 941|Homo sapiens MCF.2 cell line derived... 44 0.003
AL033403-5|CAI42108.1| 860|Homo sapiens MCF.2 cell line derived... 44 0.003
AL033403-4|CAI42106.1| 528|Homo sapiens MCF.2 cell line derived... 44 0.003
AL033403-2|CAI42104.1| 1070|Homo sapiens MCF.2 cell line derived... 44 0.003
AB085902-1|BAC41201.1| 941|Homo sapiens DBL proto-oncogene spli... 44 0.003
AB085901-1|BAC41200.1| 860|Homo sapiens DBL proto-oncogene spli... 44 0.003
J03639-1|AAA52172.1| 478|Homo sapiens MCF2 protein. 43 0.006
BC117196-1|AAI17197.1| 1591|Homo sapiens T-cell lymphoma invasio... 43 0.006
BC117192-1|AAI17193.1| 1591|Homo sapiens T-cell lymphoma invasio... 43 0.006
BC066979-1|AAH66979.1| 626|Homo sapiens T-cell lymphoma invasio... 43 0.006
AL596202-1|CAI14404.1| 1046|Homo sapiens T-cell lymphoma invasio... 43 0.006
AL355343-1|CAH73978.1| 1046|Homo sapiens T-cell lymphoma invasio... 43 0.006
AL139101-3|CAI20508.1| 1046|Homo sapiens T-cell lymphoma invasio... 43 0.006
AL033403-3|CAI42105.1| 428|Homo sapiens MCF.2 cell line derived... 43 0.006
AF120324-1|AAF05901.1| 626|Homo sapiens T-cell lymphoma invasio... 43 0.006
AF120323-1|AAF05900.1| 1077|Homo sapiens T-cell lymphoma invasio... 43 0.006
AB209679-1|BAD92916.1| 435|Homo sapiens MCF.2 cell line derived... 43 0.006
AB209674-1|BAD92911.1| 1947|Homo sapiens T-cell lymphoma invasio... 43 0.006
AB095936-1|BAC23112.2| 1715|Homo sapiens KIAA2016 protein protein. 43 0.006
X13230-1|CAA31617.1| 567|Homo sapiens protein ( Human mRNA for ... 42 0.010
AK125979-1|BAC86373.1| 738|Homo sapiens (Hapip). protein. 42 0.010
AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein. 42 0.010
AK125459-1|BAC86170.1| 1268|Homo sapiens protein ( Homo sapiens ... 41 0.023
U02082-1|AAA18010.1| 519|Homo sapiens guanine nucleotide regula... 40 0.040
BC014555-1|AAH14555.1| 519|Homo sapiens ARHGEF5 protein protein. 40 0.040
BC011839-1|AAH11839.1| 519|Homo sapiens ARHGEF5 protein protein. 40 0.040
BC010046-1|AAH10046.1| 519|Homo sapiens ARHGEF5 protein protein. 40 0.040
AY196211-1|AAP34307.1| 1577|Homo sapiens TUBA protein. 40 0.040
AL732437-4|CAI11032.1| 160|Homo sapiens neuroepithelial cell tr... 40 0.040
AL627434-2|CAI13197.1| 1601|Homo sapiens novel protein protein. 40 0.040
AL441886-1|CAI13076.1| 1601|Homo sapiens novel protein protein. 40 0.040
AL392107-2|CAI11009.1| 1601|Homo sapiens novel protein protein. 40 0.040
AK160365-1|BAD18708.1| 1651|Homo sapiens FLJ00261 protein protein. 40 0.040
AC004534-1|AAC12958.1| 519|Homo sapiens guanine nucleotide regu... 40 0.040
AB023227-1|BAA76854.1| 1315|Homo sapiens KIAA1010 protein protein. 40 0.040
BC077721-1|AAH77721.1| 1030|Homo sapiens ARHGEF18 protein protein. 39 0.093
BC041628-1|AAH41628.1| 823|Homo sapiens DNMBP protein protein. 39 0.093
AK127045-1|BAC86801.1| 1173|Homo sapiens HO-GEF). protein. 39 0.093
AK027713-1|BAB55317.1| 359|Homo sapiens protein ( Homo sapiens ... 39 0.093
AB011093-1|BAA25447.1| 1050|Homo sapiens KIAA0521 protein protein. 39 0.093
BC082974-1|AAH82974.1| 1151|Homo sapiens PLEKHG4 protein protein. 39 0.12
BC063501-1|AAH63501.1| 1191|Homo sapiens PLEKHG4 protein protein. 39 0.12
BC054486-1|AAH54486.1| 1110|Homo sapiens PLEKHG4 protein protein. 39 0.12
AK125163-1|BAC86068.1| 320|Homo sapiens protein ( Homo sapiens ... 39 0.12
AK024475-1|BAB15765.1| 1194|Homo sapiens FLJ00068 protein protein. 39 0.12
AB197663-1|BAE07054.1| 1191|Homo sapiens puratrophin-1 protein. 39 0.12
AB018336-1|BAA34513.2| 1055|Homo sapiens KIAA0793 protein protein. 39 0.12
AY536247-1|AAS46909.1| 137|Homo sapiens breakpoint cluster regi... 38 0.16
S76992-1|AAB34377.1| 878|Homo sapiens VAV2 protein. 38 0.21
BC132967-1|AAI32968.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.21
BC132965-1|AAI32966.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.21
BC031573-1|AAH31573.1| 710|Homo sapiens neuronal guanine nucleo... 38 0.21
AL590710-7|CAI12279.1| 878|Homo sapiens vav 2 oncogene protein. 38 0.21
AL590710-6|CAI12278.1| 868|Homo sapiens vav 2 oncogene protein. 38 0.21
AL590710-5|CAI12280.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.21
AL445931-3|CAI13723.1| 868|Homo sapiens vav 2 oncogene protein. 38 0.21
AL445931-2|CAI13722.1| 878|Homo sapiens vav 2 oncogene protein. 38 0.21
AL445931-1|CAI13724.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.21
AL357934-3|CAI15781.1| 868|Homo sapiens vav 2 oncogene protein. 38 0.21
AL357934-2|CAI15783.1| 878|Homo sapiens vav 2 oncogene protein. 38 0.21
AL357934-1|CAI15782.1| 839|Homo sapiens vav 2 oncogene protein. 38 0.21
AJ238899-1|CAC00686.1| 425|Homo sapiens guanine nucleotide exch... 38 0.21
AC016692-1|AAX93288.1| 582|Homo sapiens unknown protein. 38 0.21
DQ424905-1|ABD83670.1| 630|Homo sapiens rho guanine nucleotide ... 38 0.28
AB209101-1|BAD92338.1| 1060|Homo sapiens T-cell lymphoma invasio... 37 0.37
AK023960-1|BAB14741.1| 744|Homo sapiens protein ( Homo sapiens ... 37 0.50
AK024068-1|BAB14812.1| 734|Homo sapiens protein ( Homo sapiens ... 36 0.87
AB069693-1|BAB62851.1| 140|Homo sapiens bcr/abl e8a2 fusion pro... 36 1.1
BC071592-1|AAH71592.1| 1076|Homo sapiens FARP1 protein protein. 35 1.5
BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein. 35 2.0
BC035585-1|AAH35585.1| 1627|Homo sapiens Similar to triple funct... 34 2.6
AY536248-1|AAS46910.1| 164|Homo sapiens breakpoint cluster regi... 34 2.6
BC041595-1|AAH41595.1| 1045|Homo sapiens FERM, RhoGEF (ARHGEF) a... 33 4.6
AL161896-1|CAI12946.1| 1045|Homo sapiens FERM, RhoGEF (ARHGEF) a... 33 4.6
AL137249-8|CAI39458.1| 1045|Homo sapiens FERM, RhoGEF (ARHGEF) a... 33 4.6
AL136300-3|CAI10953.1| 1045|Homo sapiens FERM, RhoGEF (ARHGEF) a... 33 4.6
AB008430-1|BAA24267.1| 1045|Homo sapiens CDEP protein. 33 4.6
BX640754-1|CAE45861.1| 801|Homo sapiens hypothetical protein pr... 33 6.1
AL445933-4|CAI14538.1| 2406|Homo sapiens human immunodeficiency ... 33 8.1
AL445933-3|CAI14537.1| 2405|Homo sapiens human immunodeficiency ... 33 8.1
AF278765-1|AAK01082.1| 2406|Homo sapiens kappa B and V(D)J recom... 33 8.1
AB046775-1|BAB13381.2| 2414|Homo sapiens KIAA1555 protein protein. 33 8.1
>BC112926-1|AAI12927.1| 1306|Homo sapiens ARHGEF10 protein protein.
Length = 1306
Score = 361 bits (888), Expect = 8e-99
Identities = 233/819 (28%), Positives = 392/819 (47%), Gaps = 61/819 (7%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RR+++ +++ SE +YV L+R++ Y+KPL E P +L+ K++T+F+R+ +ILQCH
Sbjct: 356 QVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKVLSERKLKTVFYRVKEILQCH 415
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ ALA WD E IG+VF+++FSK++VLD YS+++NNFS A+ + K K A
Sbjct: 416 SLFQIALASRVSEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPA 475
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q ++ DR + + LM+KP+QRFPQFI+ LQD+LK+T GH DR+
Sbjct: 476 FLEFLKQEQEASPDRTTLYSLMMKPIQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTEL 535
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KRDA++ + R+L+
Sbjct: 536 ETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLS----------------SGSRYLI 579
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGGD------DAERLGLKWAHPV 412
R DD+++ +N G + K K RR+ +LND+++C +V + ++R LKW+ P+
Sbjct: 580 RSDDMIETVYNDRGEIVKTKERRVFMLNDVLMCATVSSRPSHDSRVMSSQRYLLKWSVPL 639
Query: 413 QDVEVLDTGTSPTL---SRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMSTLMHDYE 469
V+ ++ G+S SR LA ++ G L ++ L+HD
Sbjct: 640 GHVDAIEYGSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPG-QLYQDLQNLLHDLN 698
Query: 470 TVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGREE- 528
+ ++ L +LK Y L + +Q+ I KK+DE+ D C +QL++ G+++
Sbjct: 699 VIGQITQLIGNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQDK 758
Query: 529 -------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAW---RVPVSHAPPHKMPLFV 578
F P + W N W +H K PL V
Sbjct: 759 SGRPTFFTAVFNTFTPAIKESWVNSLQMAKLALEEENHMGWFCVEDDGNHIKKEKHPLLV 818
Query: 579 DANNVYSSKNLT-EVRCGCFYTS---SXXXXXXXXXXXXXXLWVCAGGAALSHVAVLTHR 634
V +K ++ C + + LW+ + + +A+++ +
Sbjct: 819 GHMPVMVAKQQEFKIECAAYNPEPYLNNESQPDSFSTAHGFLWIGSCTHQMGQIAIVSFQ 878
Query: 635 AAKLKTLVTLDLPDTKVTSMEFAKGIRQ--------------VTTLCGDTVWLGTEDKKI 680
+ K + ++ ++++ M + + V T+ +GTE+ I
Sbjct: 879 NSTPKVIECFNV-ESRILCMLYVPVEEKRREPGAPPDPETPAVRASDVPTICVGTEEGSI 937
Query: 681 IIFSAVEPEKQEKLAE--VPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDDSWALQEP 738
I+ + + K+ +L P + V + +++ GL NG VA Y R D SW +
Sbjct: 938 SIYKSSQGSKKVRLQHFFTPEKSTVMSLACTSQSLYAGLVNGAVASYARAPDGSWDSEPQ 997
Query: 739 LAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTVKYLAHSGV 798
I+LG PV LL ++ L+A +VF I+ T + LE + + ++A SGV
Sbjct: 998 KVIKLGVLPVRSLLMMEDTLWAASGGQVFIISVETHAVEGQLEAHQEEGMVISHMAVSGV 1057
Query: 799 GLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLASQGLLWVG 858
G+W AF+ + + L+H ET +HLQ+I+IA V + G + V++LL GLL VG
Sbjct: 1058 GIWIAFTSGSTLRLFHTETLKHLQDINIATPVHNML---PGHQRLSVTSLLVCHGLLMVG 1114
Query: 859 TTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFLL 897
T+ GV V +P+P+L+G+P V G SYHAH PV F++
Sbjct: 1115 TSLGVLVALPVPRLQGIPKVTGRGMVSYHAHNSPVKFIV 1153
>AB002292-1|BAA20754.2| 1405|Homo sapiens KIAA0294 protein.
Length = 1405
Score = 361 bits (888), Expect = 8e-99
Identities = 233/819 (28%), Positives = 392/819 (47%), Gaps = 61/819 (7%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RR+++ +++ SE +YV L+R++ Y+KPL E P +L+ K++T+F+R+ +ILQCH
Sbjct: 455 QVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKVLSERKLKTVFYRVKEILQCH 514
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ ALA WD E IG+VF+++FSK++VLD YS+++NNFS A+ + K K A
Sbjct: 515 SLFQIALASRVSEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPA 574
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q ++ DR + + LM+KP+QRFPQFI+ LQD+LK+T GH DR+
Sbjct: 575 FLEFLKQEQEASPDRTTLYSLMMKPIQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTEL 634
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KRDA++ + R+L+
Sbjct: 635 ETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLS----------------SGSRYLI 678
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGGD------DAERLGLKWAHPV 412
R DD+++ +N G + K K RR+ +LND+++C +V + ++R LKW+ P+
Sbjct: 679 RSDDMIETVYNDRGEIVKTKERRVFMLNDVLMCATVSSRPSHDSRVMSSQRYLLKWSVPL 738
Query: 413 QDVEVLDTGTSPTL---SRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMSTLMHDYE 469
V+ ++ G+S SR LA ++ G L ++ L+HD
Sbjct: 739 GHVDAIEYGSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPG-QLYQDLQNLLHDLN 797
Query: 470 TVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGREE- 528
+ ++ L +LK Y L + +Q+ I KK+DE+ D C +QL++ G+++
Sbjct: 798 VIGQITQLIGNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQDK 857
Query: 529 -------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAW---RVPVSHAPPHKMPLFV 578
F P + W N W +H K PL V
Sbjct: 858 SGRPTFFTAVFNTFTPAIKESWVNSLQMAKLALEEENHMGWFCVEDDGNHIKKEKHPLLV 917
Query: 579 DANNVYSSKNLT-EVRCGCFYTS---SXXXXXXXXXXXXXXLWVCAGGAALSHVAVLTHR 634
V +K ++ C + + LW+ + + +A+++ +
Sbjct: 918 GHMPVMVAKQQEFKIECAAYNPEPYLNNESQPDSFSTAHGFLWIGSCTHQMGQIAIVSFQ 977
Query: 635 AAKLKTLVTLDLPDTKVTSMEFAKGIRQ--------------VTTLCGDTVWLGTEDKKI 680
+ K + ++ ++++ M + + V T+ +GTE+ I
Sbjct: 978 NSTPKVIECFNV-ESRILCMLYVPVEEKRREPGAPPDPETPAVRASDVPTICVGTEEGSI 1036
Query: 681 IIFSAVEPEKQEKLAE--VPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDDSWALQEP 738
I+ + + K+ +L P + V + +++ GL NG VA Y R D SW +
Sbjct: 1037 SIYKSSQGSKKVRLQHFFTPEKSTVMSLACTSQSLYAGLVNGAVASYARAPDGSWDSEPQ 1096
Query: 739 LAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTVKYLAHSGV 798
I+LG PV LL ++ L+A +VF I+ T + LE + + ++A SGV
Sbjct: 1097 KVIKLGVLPVRSLLMMEDTLWAASGGQVFIISVETHAVEGQLEAHQEEGMVISHMAVSGV 1156
Query: 799 GLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLASQGLLWVG 858
G+W AF+ + + L+H ET +HLQ+I+IA V + G + V++LL GLL VG
Sbjct: 1157 GIWIAFTSGSTLRLFHTETLKHLQDINIATPVHNML---PGHQRLSVTSLLVCHGLLMVG 1213
Query: 859 TTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFLL 897
T+ GV V +P+P+L+G+P V G SYHAH PV F++
Sbjct: 1214 TSLGVLVALPVPRLQGIPKVTGRGMVSYHAHNSPVKFIV 1252
>AF009205-1|AAB71662.1| 988|Homo sapiens unknown protein.
Length = 988
Score = 360 bits (886), Expect = 1e-98
Identities = 235/801 (29%), Positives = 382/801 (47%), Gaps = 54/801 (6%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RR+++ +++ SE +YV L+R++ Y+KPL E P +L+ K++T+F+R+ +ILQCH
Sbjct: 67 QVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKVLSERKLKTVFYRVKEILQCH 126
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ ALA WD E IG+VF+++FSK++VLD YS+++NNFS A+ + K K A
Sbjct: 127 SLFQIALASRVSEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPA 186
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q ++ DR + + LM+KP QRFPQFI+ LQD+LK+T GH DR+
Sbjct: 187 FLEFLKQEQEASPDRTTLYSLMMKPXQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTEL 246
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KRDA++ + R+L+
Sbjct: 247 ETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLS----------------SGSRYLI 290
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGGD------DAERLGLKWAHPV 412
R DD+++ +N G + K K RR+ +LND+++C +V + ++R LKW+ P+
Sbjct: 291 RSDDMIETVYNDRGEIVKTKERRVFMLNDVLMCATVSSRPSHDSRVMSSQRYLLKWSVPL 350
Query: 413 QDVEVLDTGTSPTL---SRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMSTLMHDYE 469
V+ ++ G+S SR LA ++ G L ++ L+HD
Sbjct: 351 GHVDAIEYGSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPG-QLYQDLQNLLHDLN 409
Query: 470 TVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGREE- 528
+ ++ L +LK Y L + +Q+ I KK+DE+ D C +QL++ G+++
Sbjct: 410 VIGQITQLIGNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQDK 469
Query: 529 -------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAW---RVPVSHAPPHKMPLFV 578
F P + W N W +H K PL V
Sbjct: 470 SGRPTFFTAVFXTFTPAIKESWVNSLQMAKLALEEENHMGWFCVEDDGNHIKKEKHPLLV 529
Query: 579 DANNVYSSKNLTEVRCGCFYTSSXXXXXXXXXXXXXXLWVCAGGAALSHVAVLTHRAAKL 638
V +K E + G + C S + + + +
Sbjct: 530 GHMPVMVAKQ-QEFKIGSCTHQMGQIAIVSFQNSTPKVIECFN--VESRILCMLYVPVEE 586
Query: 639 KTLVTLDLPDTKVTSMEFAKGIRQVTTLCGDTVWLGTEDKKIIIFSAVEPEKQEKLAE-- 696
K PD + ++ + V T+C +GTE+ I I+ + + K+ +L
Sbjct: 587 KRREPGAPPDPETPAVRAS----DVPTIC-----VGTEEGSISIYKSSQGSKKVRLQHFF 637
Query: 697 VPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDDSWALQEPLAIELGDKPVHCLLPVDG 756
P ++V + +++ GL NG VA Y R D SW + I+LG PV LL ++
Sbjct: 638 TPEKSSVMSLACTSQSLYAGLVNGAVATYARAPDGSWDSEPQKVIKLGVLPVRSLLMMED 697
Query: 757 ILYATCARRVFAINALTAEIMRILELKSDGDRTVKYLAHSGVGLWTAFSDSTFVSLYHAE 816
L+A +VF I+ T + LE + + ++A SGVG+W AF+ + + L+H E
Sbjct: 698 TLWAASGGQVFIISVETHAVEGQLEAHQEEGMVISHMAVSGVGIWIAFTSGSTLRLFHTE 757
Query: 817 TFEHLQNIDIAADVAKTIGARDGSKPAYVSALLASQGLLWVGTTAGVSVTVPLPKLEGLP 876
T +HLQ+I+IA V + G + V++LL GLL VGT+ GV V +P+P+L+G+P
Sbjct: 758 TLKHLQDINIATPVHNML---PGHQRLSVTSLLVCHGLLMVGTSLGVLVALPVPRLQGIP 814
Query: 877 LVGGHIAGSYHAHAGPVTFLL 897
V G SYHAH PV F++
Sbjct: 815 KVTGRGMVSYHAHNSPVKFIV 835
>DQ139833-1|AAZ73162.1| 1235|Homo sapiens GrinchGEF protein.
Length = 1235
Score = 342 bits (840), Expect = 5e-93
Identities = 242/821 (29%), Positives = 382/821 (46%), Gaps = 63/821 (7%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 275 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 334
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ AL+ WD EKIG++F+++FSK++VLDVYSD++NNF+ AM + K K A
Sbjct: 335 SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPA 394
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 395 FLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTEL 454
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KR A++ + +R LL
Sbjct: 455 ETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLL 499
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGG----DDAERLG----LKW-- 408
+ L + + G L K K RR+ LLND++VC ++ G LG +KW
Sbjct: 500 LCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWNT 559
Query: 409 AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMSTLMHD 467
A P VQ VEV G + VL Q ++ L E+ L D
Sbjct: 560 ALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQDLQKD 618
Query: 468 YETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGRE 527
V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L + G+
Sbjct: 619 LAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKP 678
Query: 528 E--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPPHKMPL 576
+ + F P +++ W N P W P P P+
Sbjct: 679 DKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPI 738
Query: 577 FVDANNVYSSKNLTEVRCGCFYTSS-----XXXXXXXXXXXXXXLWVCAG-GAALSHVAV 630
+SS+ L+ ++ G S LWV G A V +
Sbjct: 739 LACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEI 797
Query: 631 LTHRAAKLKTLVTLDLP------------DTKVTSMEFAKGIRQVTTLCGDTVWLGTEDK 678
+ +T+ + L + + S + + + + T+ LG +D
Sbjct: 798 FSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICLGLQDG 857
Query: 679 KIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD-SWALQ 736
I+++S+V+ Q ++ P + V +R+ + GL +G +A Y R W L+
Sbjct: 858 SILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLWDLE 917
Query: 737 E-PLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTVKYLAH 795
P+ + +G PV LL ++ ++A+C RV + A T + + E D +V ++
Sbjct: 918 SPPVCLTVGPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQDEAVSVTHMVK 977
Query: 796 SGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLASQGLL 855
+G G+W AFS T + L+H ET EHLQ I+IA +T G K V++LL QGLL
Sbjct: 978 AGSGVWMAFSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLICQGLL 1034
Query: 856 WVGTTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
WVGT GV V +P+P+LEG+P + G S + H GPV FL
Sbjct: 1035 WVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 1075
>AL358593-3|CAH74137.1| 1052|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 10-like protein.
Length = 1052
Score = 338 bits (832), Expect = 5e-92
Identities = 241/821 (29%), Positives = 381/821 (46%), Gaps = 63/821 (7%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 92 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 151
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ AL+ WD EKIG++F+++FSK++VLDVYSD++NNF+ AM + K K A
Sbjct: 152 SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPA 211
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 212 FLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTEL 271
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KR A++ + +R LL
Sbjct: 272 ETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLL 316
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGG----DDAERLG----LKW-- 408
+ L + + G L K K RR+ LLND++VC ++ G LG +KW
Sbjct: 317 LCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWNT 376
Query: 409 AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMSTLMHD 467
A P VQ VEV G + VL Q ++ L E+ L D
Sbjct: 377 ALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQDLQKD 435
Query: 468 YETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGRE 527
V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L + G+
Sbjct: 436 LAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKP 495
Query: 528 E--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPPHKMPL 576
+ + F P +++ W N P W P P P+
Sbjct: 496 DKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPI 555
Query: 577 FVDANNVYSSKNLTEVRCGCFYTSS-----XXXXXXXXXXXXXXLWVCAG-GAALSHVAV 630
+SS+ L+ ++ G S LWV G A V +
Sbjct: 556 LACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEI 614
Query: 631 LTHRAAKLKTLVTLDLP------------DTKVTSMEFAKGIRQVTTLCGDTVWLGTEDK 678
+ +T+ + L + + S + + + + T+ LG +D
Sbjct: 615 FSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICLGLQDG 674
Query: 679 KIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD-SWALQ 736
I+++S+V+ Q ++ P + V +R+ + GL +G +A Y R W L+
Sbjct: 675 SILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLWDLE 734
Query: 737 E-PLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTVKYLAH 795
P+ + +G PV LL ++ ++A+C V + A T + + E D +V ++
Sbjct: 735 SPPVCLTVGPGPVRTLLSLEDAVWASCGPWVTVLEATTLQPQQSFEAHQDEAVSVTHMVK 794
Query: 796 SGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLASQGLL 855
+G G+W AFS T + L+H ET EHLQ I+IA +T G K V++LL QGLL
Sbjct: 795 AGSGVWMAFSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLICQGLL 851
Query: 856 WVGTTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
WVGT GV V +P+P+LEG+P + G S + H GPV FL
Sbjct: 852 WVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 892
>BC117171-1|AAI17172.1| 1240|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 10-like protein.
Length = 1240
Score = 335 bits (823), Expect = 6e-91
Identities = 241/826 (29%), Positives = 382/826 (46%), Gaps = 68/826 (8%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 275 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 334
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ AL+ WD EKIG++F+++FSK++VLDVYSD++NNF+ AM + K K A
Sbjct: 335 SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPA 394
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 395 FLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTEL 454
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KR A++ + +R LL
Sbjct: 455 ETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLL 499
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVG------AGGDDAERL-------G 405
+ L + + G L K K RR+ LLND++VC ++ G + L
Sbjct: 500 LCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYV 559
Query: 406 LKW--AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMS 462
+KW A P VQ VEV G + VL Q ++ L E+
Sbjct: 560 VKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQ 618
Query: 463 TLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLR 522
L D V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L
Sbjct: 619 DLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLL 678
Query: 523 IRGREE--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPP 571
+ G+ + + F P +++ W N P W P P
Sbjct: 679 LPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAP 738
Query: 572 HKMPLFVDANNVYSSKNLTEVRCGCFYTSS-----XXXXXXXXXXXXXXLWVCAG-GAAL 625
P+ +SS+ L+ ++ G S LWV G A
Sbjct: 739 FWCPILACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAG 797
Query: 626 SHVAVLTHRAAKLKTLVTLDLP------------DTKVTSMEFAKGIRQVTTLCGDTVWL 673
V + + +T+ + L + + S + + + + T+ L
Sbjct: 798 GQVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICL 857
Query: 674 GTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD- 731
G +D I+++S+V+ Q ++ P + V +R+ + GL +G +A Y R
Sbjct: 858 GLQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGV 917
Query: 732 SWALQE-PLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTV 790
W L+ P+ + +G PV LL ++ ++A+C RV + A T + + E D +V
Sbjct: 918 LWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQDEAVSV 977
Query: 791 KYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLA 850
++ +G G+W AFS T + L+H ET EHLQ I+IA +T G K V++LL
Sbjct: 978 THMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLI 1034
Query: 851 SQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
QGLLWVGT GV V +P+P+LEG+P + G S + H GPV FL
Sbjct: 1035 CQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 1080
>AB046846-1|BAB13452.1| 1284|Homo sapiens KIAA1626 protein protein.
Length = 1284
Score = 335 bits (823), Expect = 6e-91
Identities = 241/826 (29%), Positives = 382/826 (46%), Gaps = 68/826 (8%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 319 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 378
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ AL+ WD EKIG++F+++FSK++VLDVYSD++NNF+ AM + K K A
Sbjct: 379 SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPA 438
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 439 FLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTEL 498
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KR A++ + +R LL
Sbjct: 499 ETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLL 543
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVG------AGGDDAERL-------G 405
+ L + + G L K K RR+ LLND++VC ++ G + L
Sbjct: 544 LCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYV 603
Query: 406 LKW--AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMS 462
+KW A P VQ VEV G + VL Q ++ L E+
Sbjct: 604 VKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQ 662
Query: 463 TLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLR 522
L D V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L
Sbjct: 663 DLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLL 722
Query: 523 IRGREE--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPP 571
+ G+ + + F P +++ W N P W P P
Sbjct: 723 LPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAP 782
Query: 572 HKMPLFVDANNVYSSKNLTEVRCGCFYTSS-----XXXXXXXXXXXXXXLWVCAG-GAAL 625
P+ +SS+ L+ ++ G S LWV G A
Sbjct: 783 FWCPILACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAG 841
Query: 626 SHVAVLTHRAAKLKTLVTLDLP------------DTKVTSMEFAKGIRQVTTLCGDTVWL 673
V + + +T+ + L + + S + + + + T+ L
Sbjct: 842 GQVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICL 901
Query: 674 GTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD- 731
G +D I+++S+V+ Q ++ P + V +R+ + GL +G +A Y R
Sbjct: 902 GLQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGV 961
Query: 732 SWALQE-PLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTV 790
W L+ P+ + +G PV LL ++ ++A+C RV + A T + + E D +V
Sbjct: 962 LWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQDEAVSV 1021
Query: 791 KYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLA 850
++ +G G+W AFS T + L+H ET EHLQ I+IA +T G K V++LL
Sbjct: 1022 THMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLI 1078
Query: 851 SQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
QGLLWVGT GV V +P+P+LEG+P + G S + H GPV FL
Sbjct: 1079 CQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 1124
>AL358593-2|CAH74136.1| 1240|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 10-like protein.
Length = 1240
Score = 332 bits (815), Expect = 6e-90
Identities = 240/826 (29%), Positives = 381/826 (46%), Gaps = 68/826 (8%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 275 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 334
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ AL+ WD EKIG++F+++FSK++VLDVYSD++NNF+ AM + K K A
Sbjct: 335 SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPA 394
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 395 FLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTEL 454
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KR A++ + +R LL
Sbjct: 455 ETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLL 499
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVG------AGGDDAERL-------G 405
+ L + + G L K K RR+ LLND++VC ++ G + L
Sbjct: 500 LCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYV 559
Query: 406 LKW--AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMS 462
+KW A P VQ VEV G + VL Q ++ L E+
Sbjct: 560 VKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQ 618
Query: 463 TLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLR 522
L D V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L
Sbjct: 619 DLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLL 678
Query: 523 IRGREE--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPP 571
+ G+ + + F P +++ W N P W P P
Sbjct: 679 LPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAP 738
Query: 572 HKMPLFVDANNVYSSKNLTEVRCGCFYTSS-----XXXXXXXXXXXXXXLWVCAG-GAAL 625
P+ +SS+ L+ ++ G S LWV G A
Sbjct: 739 FWCPILACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAG 797
Query: 626 SHVAVLTHRAAKLKTLVTLDLP------------DTKVTSMEFAKGIRQVTTLCGDTVWL 673
V + + +T+ + L + + S + + + + T+ L
Sbjct: 798 GQVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICL 857
Query: 674 GTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD- 731
G +D I+++S+V+ Q ++ P + V +R+ + GL +G +A Y R
Sbjct: 858 GLQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGV 917
Query: 732 SWALQE-PLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTV 790
W L+ P+ + +G PV LL ++ ++A+C V + A T + + E D +V
Sbjct: 918 LWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPWVTVLEATTLQPQQSFEAHQDEAVSV 977
Query: 791 KYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLA 850
++ +G G+W AFS T + L+H ET EHLQ I+IA +T G K V++LL
Sbjct: 978 THMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLI 1034
Query: 851 SQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
QGLLWVGT GV V +P+P+LEG+P + G S + H GPV FL
Sbjct: 1035 CQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 1080
>AL358593-1|CAH74135.1| 1279|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 10-like protein.
Length = 1279
Score = 332 bits (815), Expect = 6e-90
Identities = 240/826 (29%), Positives = 381/826 (46%), Gaps = 68/826 (8%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 314 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 373
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ AL+ WD EKIG++F+++FSK++VLDVYSD++NNF+ AM + K K A
Sbjct: 374 SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPA 433
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 434 FLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTEL 493
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KR A++ + +R LL
Sbjct: 494 ETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLL 538
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVG------AGGDDAERL-------G 405
+ L + + G L K K RR+ LLND++VC ++ G + L
Sbjct: 539 LCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYV 598
Query: 406 LKW--AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMS 462
+KW A P VQ VEV G + VL Q ++ L E+
Sbjct: 599 VKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQ 657
Query: 463 TLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLR 522
L D V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L
Sbjct: 658 DLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLL 717
Query: 523 IRGREE--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPP 571
+ G+ + + F P +++ W N P W P P
Sbjct: 718 LPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAP 777
Query: 572 HKMPLFVDANNVYSSKNLTEVRCGCFYTSS-----XXXXXXXXXXXXXXLWVCAG-GAAL 625
P+ +SS+ L+ ++ G S LWV G A
Sbjct: 778 FWCPILACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAG 836
Query: 626 SHVAVLTHRAAKLKTLVTLDLP------------DTKVTSMEFAKGIRQVTTLCGDTVWL 673
V + + +T+ + L + + S + + + + T+ L
Sbjct: 837 GQVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICL 896
Query: 674 GTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD- 731
G +D I+++S+V+ Q ++ P + V +R+ + GL +G +A Y R
Sbjct: 897 GLQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGV 956
Query: 732 SWALQE-PLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTV 790
W L+ P+ + +G PV LL ++ ++A+C V + A T + + E D +V
Sbjct: 957 LWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPWVTVLEATTLQPQQSFEAHQDEAVSV 1016
Query: 791 KYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLA 850
++ +G G+W AFS T + L+H ET EHLQ I+IA +T G K V++LL
Sbjct: 1017 THMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLI 1073
Query: 851 SQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
QGLLWVGT GV V +P+P+LEG+P + G S + H GPV FL
Sbjct: 1074 CQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 1119
>AL139250-2|CAI22140.1| 1240|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 10-like protein.
Length = 1240
Score = 332 bits (815), Expect = 6e-90
Identities = 240/826 (29%), Positives = 381/826 (46%), Gaps = 68/826 (8%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 275 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 334
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ AL+ WD EKIG++F+++FSK++VLDVYSD++NNF+ AM + K K A
Sbjct: 335 SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPA 394
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 395 FLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTEL 454
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KR A++ + +R LL
Sbjct: 455 ETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLL 499
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVG------AGGDDAERL-------G 405
+ L + + G L K K RR+ LLND++VC ++ G + L
Sbjct: 500 LCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYV 559
Query: 406 LKW--AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMS 462
+KW A P VQ VEV G + VL Q ++ L E+
Sbjct: 560 VKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQ 618
Query: 463 TLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLR 522
L D V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L
Sbjct: 619 DLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLL 678
Query: 523 IRGREE--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPP 571
+ G+ + + F P +++ W N P W P P
Sbjct: 679 LPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAP 738
Query: 572 HKMPLFVDANNVYSSKNLTEVRCGCFYTSS-----XXXXXXXXXXXXXXLWVCAG-GAAL 625
P+ +SS+ L+ ++ G S LWV G A
Sbjct: 739 FWCPILACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAG 797
Query: 626 SHVAVLTHRAAKLKTLVTLDLP------------DTKVTSMEFAKGIRQVTTLCGDTVWL 673
V + + +T+ + L + + S + + + + T+ L
Sbjct: 798 GQVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICL 857
Query: 674 GTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD- 731
G +D I+++S+V+ Q ++ P + V +R+ + GL +G +A Y R
Sbjct: 858 GLQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGV 917
Query: 732 SWALQE-PLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTV 790
W L+ P+ + +G PV LL ++ ++A+C V + A T + + E D +V
Sbjct: 918 LWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPWVTVLEATTLQPQQSFEAHQDEAVSV 977
Query: 791 KYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLA 850
++ +G G+W AFS T + L+H ET EHLQ I+IA +T G K V++LL
Sbjct: 978 THMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLI 1034
Query: 851 SQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
QGLLWVGT GV V +P+P+LEG+P + G S + H GPV FL
Sbjct: 1035 CQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 1080
>AL139250-1|CAI22139.1| 1279|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 10-like protein.
Length = 1279
Score = 332 bits (815), Expect = 6e-90
Identities = 240/826 (29%), Positives = 381/826 (46%), Gaps = 68/826 (8%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 314 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 373
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ AL+ WD EKIG++F+++FSK++VLDVYSD++NNF+ AM + K K A
Sbjct: 374 SMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPA 433
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 434 FLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTEL 493
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KR A++ + +R LL
Sbjct: 494 ETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLL 538
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVG------AGGDDAERL-------G 405
+ L + + G L K K RR+ LLND++VC ++ G + L
Sbjct: 539 LCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYV 598
Query: 406 LKW--AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMS 462
+KW A P VQ VEV G + VL Q ++ L E+
Sbjct: 599 VKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQ 657
Query: 463 TLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLR 522
L D V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L
Sbjct: 658 DLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLL 717
Query: 523 IRGREE--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPP 571
+ G+ + + F P +++ W N P W P P
Sbjct: 718 LPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAP 777
Query: 572 HKMPLFVDANNVYSSKNLTEVRCGCFYTSS-----XXXXXXXXXXXXXXLWVCAG-GAAL 625
P+ +SS+ L+ ++ G S LWV G A
Sbjct: 778 FWCPILACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAG 836
Query: 626 SHVAVLTHRAAKLKTLVTLDLP------------DTKVTSMEFAKGIRQVTTLCGDTVWL 673
V + + +T+ + L + + S + + + + T+ L
Sbjct: 837 GQVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICL 896
Query: 674 GTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD- 731
G +D I+++S+V+ Q ++ P + V +R+ + GL +G +A Y R
Sbjct: 897 GLQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGV 956
Query: 732 SWALQE-PLAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTV 790
W L+ P+ + +G PV LL ++ ++A+C V + A T + + E D +V
Sbjct: 957 LWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPWVTVLEATTLQPQQSFEAHQDEAVSV 1016
Query: 791 KYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLA 850
++ +G G+W AFS T + L+H ET EHLQ I+IA +T G K V++LL
Sbjct: 1017 THMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLI 1073
Query: 851 SQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
QGLLWVGT GV V +P+P+LEG+P + G S + H GPV FL
Sbjct: 1074 CQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 1119
>BC080596-1|AAH80596.1| 886|Homo sapiens ARHGEF10L protein protein.
Length = 886
Score = 257 bits (630), Expect = 1e-67
Identities = 209/747 (27%), Positives = 331/747 (44%), Gaps = 70/747 (9%)
Query: 199 GEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFKVKQISAHDRLSFFG 258
G++F+++FSK++VLDVYSD++NNF+ AM + K K A +F K +Q+ + DR++ +G
Sbjct: 1 GDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPAFLEFLKRRQVCSPDRVTLYG 60
Query: 259 LMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXXXXXXXXXXXXKRDAERTQXX 318
LMVKP+QRFPQFI+ LQD+LK+TP GH DR+ KR A++
Sbjct: 61 LMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELETLAEKLNEQKRLADQVAEI 120
Query: 319 XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLLRQDDLLQMEFNQSGGLSKCK 378
+ +R LL + L + + G L K K
Sbjct: 121 QQLTKSVSDRSSLNKLLT---------------SGQRQLLLCETLTETVYGDRGQLIKSK 165
Query: 379 PRRLLLLNDLVVCVSVG------AGGDDAERLG-------LKW--AHP-VQDVEVLDTGT 422
RR+ LLND++VC ++ G + L +KW A P VQ VEV G
Sbjct: 166 ERRVFLLNDMLVCANINFKPANHRGQLEISSLVPLGPKYVVKWNTALPQVQVVEVGQDGG 225
Query: 423 SPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMSTLMHDYETVSRMADLAASLK 482
+ VL Q ++ L E+ L D V ++ L ++L
Sbjct: 226 TYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQDLQKDLAVVEQITLLISTLH 284
Query: 483 TPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGREEA--------LTFRA 534
Y L + + ++Q+ ++ K++E+ + C L+L + G+ + + F
Sbjct: 285 GTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKSGRPISFMVVFIT 344
Query: 535 NEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPPHKMPLFVDANNVYSSKNLTE 591
P +++ W N P W P P P+ +SS+ L+
Sbjct: 345 PNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILACCIPAFSSRALS- 403
Query: 592 VRCGCFYTSSXX-----XXXXXXXXXXXXLWVCAGG-AALSHVAVLTHRAAKLKTLVTLD 645
++ G S LWV G A V + + +T+ +
Sbjct: 404 LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRPSPRTVKSFP 463
Query: 646 LPDTKVTSMEFAKGI------RQVTTLCGD-------TVWLGTEDKKIIIFSAVEPEKQE 692
L V ME+ + R + D T+ LG +D I+++S+V+ Q
Sbjct: 464 LA-APVLCMEYIPELEEEAESRDESPTVADPSATVHPTICLGLQDGSILLYSSVDTGTQC 522
Query: 693 KLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDDS-WALQEP-LAIELGDKPVH 749
++ P + V +R+ + GL +G +A Y R W L+ P + + +G PV
Sbjct: 523 LVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLWDLESPPVCLTVGPGPVR 582
Query: 750 CLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTVKYLAHSGVGLWTAFSDSTF 809
LL ++ ++A+C RV + A T + + E D +V ++ +G G+W AFS T
Sbjct: 583 TLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQDEAVSVTHMVKAGSGVWMAFSSGTS 642
Query: 810 VSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLASQGLLWVGTTAGVSVTVPL 869
+ L+H ET EHLQ I+IA +T G K V++LL QGLLWVGT GV V +P+
Sbjct: 643 IRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLICQGLLWVGTDQGVIVLLPV 699
Query: 870 PKLEGLPLVGGHIAGSYHAHAGPVTFL 896
P+LEG+P + G S + H GPV FL
Sbjct: 700 PRLEGIPKITGKGMVSLNGHCGPVAFL 726
>BC036809-1|AAH36809.1| 660|Homo sapiens ARHGEF10 protein protein.
Length = 660
Score = 235 bits (576), Expect = 5e-61
Identities = 131/419 (31%), Positives = 220/419 (52%), Gaps = 26/419 (6%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RR+++ +++ SE +YV L+R++ Y+KPL E P +L+ K++T+F+R+ +ILQCH
Sbjct: 132 QVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKVLSERKLKTVFYRVKEILQCH 191
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ ALA WD E IG+VF+++FSK++VLD YS+++NNFS A+ + K K A
Sbjct: 192 SLFQIALASRVSEWDSVEMIGDVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPA 251
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q ++ DR + + LM+KP+QRFPQFI+ LQD+LK+T GH DR+
Sbjct: 252 FLEFLKQEQEASPDRTTLYSLMMKPIQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTEL 311
Query: 299 XXXXXXXXXXKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLL 358
KRDA++ + R+L+
Sbjct: 312 ETLAEKLNERKRDADQRCEVKQIAKAINERYLNKLLS----------------SGSRYLI 355
Query: 359 RQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGGD------DAERLGLKWAHPV 412
R DD+++ +N G + K K RR+ +LND+++C +V + ++R LKW+ P+
Sbjct: 356 RSDDMIETVYNDRGEIVKTKERRVFMLNDVLMCATVSSRPSHDSRVMSSQRYLLKWSVPL 415
Query: 413 QDVEVLDTGTSPTL---SRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMSTLMHDYE 469
V+ ++ G+S SR LA ++ G L ++ L+HD
Sbjct: 416 GHVDAIEYGSSAGTGEHSRHLAVHPPESLAVVANAKPNKVYMGPG-QLYQDLQNLLHDLN 474
Query: 470 TVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGREE 528
+ ++ L +LK Y L + +Q+ I KK+DE+ D C +QL++ G+++
Sbjct: 475 VIGQITQLIGNLKGNYQNLNQSVAHDWTSGLQRLILKKEDEIRAADCCRIQLQLPGKQD 533
>BC065561-1|AAH65561.1| 832|Homo sapiens ARHGEF10L protein protein.
Length = 832
Score = 213 bits (521), Expect = 2e-54
Identities = 187/693 (26%), Positives = 295/693 (42%), Gaps = 65/693 (9%)
Query: 248 ISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXXXXXXXXXXX 307
+ + DR++ +GLMVKP+QRFPQFI+ LQD+LK+TP GH DR+
Sbjct: 1 VCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELETLAEKLNE 60
Query: 308 XKRDAERTQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSRADKRHLLRQDDLLQME 367
KR A++ + +R LL + L +
Sbjct: 61 QKRLADQVAEIQQLTKSVSDRSSLNKLLT---------------SGQRQLLLCETLTETV 105
Query: 368 FNQSGGLSKCKPRRLLLLNDLVVCVSVGAGGD----DAERLG----LKW--AHP-VQDVE 416
+ G L K K RR+ LLND++VC ++ G LG +KW A P VQ VE
Sbjct: 106 YGDRGQLIKSKERRVFLLNDMLVCANINFKGQLEISSLVPLGPKYVVKWNTALPQVQVVE 165
Query: 417 VLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMSTLMHDYETVSRMAD 476
V G + VL Q ++ L E+ L D V ++
Sbjct: 166 VGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQDLQKDLAVVEQITL 224
Query: 477 LAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLRIRGREEA------- 529
L ++L Y L + + ++Q+ ++ K++E+ + C L+L + G+ +
Sbjct: 225 LISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKSGRPISF 284
Query: 530 -LTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPPHKMPLFVDANNVYS 585
+ F P +++ W N P W P P P+ +S
Sbjct: 285 MVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILACCIPAFS 344
Query: 586 SKNLTEVRCGCFYTSSXX-----XXXXXXXXXXXXLWVCAGG-AALSHVAVLTHRAAKLK 639
S+ L+ ++ G S LWV G A V + + +
Sbjct: 345 SRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRPSPR 403
Query: 640 TLVTLDLPDTKVTSMEFAKGI------RQVTTLCGD-------TVWLGTEDKKIIIFSAV 686
T+ + L V ME+ + R + D T+ LG +D I+++S+V
Sbjct: 404 TVKSFPLA-APVLCMEYIPELEEEAESRDESPTVADPSATVHPTICLGLQDGSILLYSSV 462
Query: 687 EPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDDS-WALQEP-LAIEL 743
+ Q ++ P + V +R+ + GL +G +A Y R W L+ P + + +
Sbjct: 463 DTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLWDLESPPVCLTV 522
Query: 744 GDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRTVKYLAHSGVGLWTA 803
G PV LL ++ ++A+C RV + A T + + E D +V ++ +G G+W A
Sbjct: 523 GPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQDEAVSVTHMVKAGSGVWMA 582
Query: 804 FSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDGSKPAYVSALLASQGLLWVGTTAGV 863
FS T + L+H ET EHLQ I+IA +T G K V++LL QGLLWVGT GV
Sbjct: 583 FSSGTSIRLFHTETLEHLQEINIA---TRTTFLLPGQKHLCVTSLLICQGLLWVGTDQGV 639
Query: 864 SVTVPLPKLEGLPLVGGHIAGSYHAHAGPVTFL 896
V +P+P+LEG+P + G S + H GPV FL
Sbjct: 640 IVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFL 672
>BC040474-1|AAH40474.1| 380|Homo sapiens ARHGEF10 protein protein.
Length = 380
Score = 181 bits (441), Expect = 1e-44
Identities = 82/196 (41%), Positives = 127/196 (64%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RR+++ +++ SE +YV L+R++ Y+KPL E P +L+ K++T+F+R+ +ILQCH
Sbjct: 150 QVVRRYILGSVVDSEKNYVDALKRILEQYEKPLSEMEPKVLSERKLKTVFYRVKEILQCH 209
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F+ ALA WD E IG VF+++FSK++VLD YS+++NNFS A+ + K K A
Sbjct: 210 SLFQIALASRVSEWDSVEMIGVVFVASFSKSMVLDAYSEYVNNFSTAVAVLKKTCATKPA 269
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXXXXXXXXX 298
+F K +Q ++ DR + + LM+KP+QRFPQFI+ LQD+LK+T GH DR+
Sbjct: 270 FLEFLKQEQEASPDRTTLYSLMMKPIQRFPQFILLLQDMLKNTSKGHPDRLPLQMALTEL 329
Query: 299 XXXXXXXXXXKRDAER 314
KRDA++
Sbjct: 330 ETLAEKLNERKRDADQ 345
>AF378754-1|AAL11991.1| 2063|Homo sapiens tumor endothelial marker 4
protein.
Length = 2063
Score = 124 bits (299), Expect = 2e-27
Identities = 54/167 (32%), Positives = 101/167 (60%), Gaps = 1/167 (0%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAIL-NASKIQTLFHRLPDILQCHLH 180
R+HV ++ +E SYV +L+ L+ Y +PL++ ++L + S + +F ++P++L+ H
Sbjct: 1067 RKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQ 1126
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
F + C QTW +K+G + + +FSK V++++YS +I+NF A + ++ + + A
Sbjct: 1127 FLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFL 1186
Query: 241 DFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
F + ++ + LM+KPVQR P++ + ++DLLKHTP H D
Sbjct: 1187 KFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPD 1233
Score = 119 bits (287), Expect = 5e-26
Identities = 76/244 (31%), Positives = 122/244 (50%), Gaps = 11/244 (4%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRN 728
+VWLGTED + ++ + + + + + ++ A+VT I Y + +FV L NG + VY+R
Sbjct: 1740 SVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQRE 1799
Query: 729 HDDSWALQEPLAIELGDK--PVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDG 786
W Q ++ LG + P+ ++ V G L+ C RV ++ T ++ + + D
Sbjct: 1800 AGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDS 1859
Query: 787 DRTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDG----SKP 842
R V + S +G+W S V LYH +TFE L +D+ V + + D K
Sbjct: 1860 SRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKA 1919
Query: 843 A--YVSALLASQGLLWVGTTAGVSVTVPL-PKLEGLPLVGGHIAGSYHAHAGPVTFLLSL 899
A ++ALL + LLWVGT+AGV +T+P P P G H G V FL ++
Sbjct: 1920 ACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAV 1979
Query: 900 -LPE 902
LP+
Sbjct: 1980 QLPD 1983
>AB002335-1|BAA20795.2| 1609|Homo sapiens KIAA0337 protein.
Length = 1609
Score = 124 bits (299), Expect = 2e-27
Identities = 54/167 (32%), Positives = 101/167 (60%), Gaps = 1/167 (0%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAIL-NASKIQTLFHRLPDILQCHLH 180
R+HV ++ +E SYV +L+ L+ Y +PL++ ++L + S + +F ++P++L+ H
Sbjct: 613 RKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQ 672
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
F + C QTW +K+G + + +FSK V++++YS +I+NF A + ++ + + A
Sbjct: 673 FLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFL 732
Query: 241 DFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
F + ++ + LM+KPVQR P++ + ++DLLKHTP H D
Sbjct: 733 KFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPD 779
Score = 119 bits (287), Expect = 5e-26
Identities = 76/244 (31%), Positives = 122/244 (50%), Gaps = 11/244 (4%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRN 728
+VWLGTED + ++ + + + + + ++ A+VT I Y + +FV L NG + VY+R
Sbjct: 1286 SVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQRE 1345
Query: 729 HDDSWALQEPLAIELGDK--PVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDG 786
W Q ++ LG + P+ ++ V G L+ C RV ++ T ++ + + D
Sbjct: 1346 AGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDS 1405
Query: 787 DRTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIGARDG----SKP 842
R V + S +G+W S V LYH +TFE L +D+ V + + D K
Sbjct: 1406 SRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKA 1465
Query: 843 A--YVSALLASQGLLWVGTTAGVSVTVPL-PKLEGLPLVGGHIAGSYHAHAGPVTFLLSL 899
A ++ALL + LLWVGT+AGV +T+P P P G H G V FL ++
Sbjct: 1466 ACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAV 1525
Query: 900 -LPE 902
LP+
Sbjct: 1526 QLPD 1529
>AK001383-1|BAA91663.1| 596|Homo sapiens protein ( Homo sapiens
cDNA FLJ10521 fis, clone NT2RP2000841. ).
Length = 596
Score = 118 bits (285), Expect = 9e-26
Identities = 127/518 (24%), Positives = 212/518 (40%), Gaps = 47/518 (9%)
Query: 354 KRHLLRQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGGD----DAERLG---- 405
+R LL + L + + G L K K RR+ LLND++VC ++ G LG
Sbjct: 63 QRQLLLCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKGQLEISSLVPLGPKYV 122
Query: 406 LKW--AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMS 462
+KW A P VQ VEV G + VL Q ++ L E+
Sbjct: 123 VKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQ 181
Query: 463 TLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLR 522
L D V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L
Sbjct: 182 DLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLL 241
Query: 523 IRGREEA--------LTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP---VSHAPP 571
+ G+ + + F P +++ W N P W P P
Sbjct: 242 LPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAP 301
Query: 572 HKMPLFVDANNVYSSKNLTEVRCGCFYTSSXX-----XXXXXXXXXXXXLWVCAGG-AAL 625
P+ +SS+ L+ ++ G S LWV G A
Sbjct: 302 FWCPILACCIPAFSSRALS-LQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAG 360
Query: 626 SHVAVLTHRAAKLKTLVTLDLPDTKVTSMEFAKGI------RQVTTLCGD-------TVW 672
V + + +T+ + L V ME+ + R + D T+
Sbjct: 361 GQVEIFSLNRPSPRTVKSFPLA-APVLCMEYIPELEEEAESRDESPTVADPSATVHPTIC 419
Query: 673 LGTEDKKIIIFSAVEPEKQEKLA-EVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNHDD 731
LG +D I+++S+V+ Q ++ P V +R+ + GL +G +A Y R
Sbjct: 420 LGLQDGSILLYSSVDTGTQCLVSCRSPGPQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGG 479
Query: 732 S-WALQEP-LAIELGDKPVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGDRT 789
W L+ P + + +G PV LL ++ ++A+C RV + A T + + E D +
Sbjct: 480 VLWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSSEAHQDEAVS 539
Query: 790 VKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIA 827
V ++ +G G+W AFS T + L+H ET EHLQ I+IA
Sbjct: 540 VTHMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIA 577
>AY850123-1|AAX47276.1| 1307|Homo sapiens sperm associated antigen 9
transcript variant 1 protein.
Length = 1307
Score = 95.9 bits (228), Expect = 8e-19
Identities = 59/220 (26%), Positives = 111/220 (50%), Gaps = 6/220 (2%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + S+V + ++ L + ++ I + + V L +G +A++ R
Sbjct: 957 TMWLGAQNGCLYVHSSVA-QWRKCLHSIKLKDSILSIVHVKGIVLVALADGTLAIFHRGV 1015
Query: 730 DDSWALQEPLAIELGDKPVH---CLLPVDGILYATCARRVFAINALTAEIMRILELKSDG 786
D W L ++LG +P H C+ V ++ +++ + +I + +
Sbjct: 1016 DGQWDLSNYHLLDLG-RPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRK 1074
Query: 787 DRTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYV 845
+ V+ LA G G+W + + + LYHA T++HLQ++DI V+K +G + G +
Sbjct: 1075 ESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRI 1134
Query: 846 SALLASQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGS 885
+AL+ S LWVGT GV +++PL + V G+ GS
Sbjct: 1135 TALMVSCNRLWVGTGNGVIISIPLTETNKTSGVPGNRPGS 1174
>AF327452-1|AAN61565.1| 1311|Homo sapiens JNK-associated
leucine-zipper protein protein.
Length = 1311
Score = 95.9 bits (228), Expect = 8e-19
Identities = 59/220 (26%), Positives = 111/220 (50%), Gaps = 6/220 (2%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + S+V + ++ L + ++ I + + V L +G +A++ R
Sbjct: 961 TMWLGAQNGCLYVHSSVA-QWRKCLHSIKLKDSILSIVHVKGIVLVALADGTLAIFHRGV 1019
Query: 730 DDSWALQEPLAIELGDKPVH---CLLPVDGILYATCARRVFAINALTAEIMRILELKSDG 786
D W L ++LG +P H C+ V ++ +++ + +I + +
Sbjct: 1020 DGQWDLSNYHLLDLG-RPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRK 1078
Query: 787 DRTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYV 845
+ V+ LA G G+W + + + LYHA T++HLQ++DI V+K +G + G +
Sbjct: 1079 ESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRI 1138
Query: 846 SALLASQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGS 885
+AL+ S LWVGT GV +++PL + V G+ GS
Sbjct: 1139 TALMVSCNRLWVGTGNGVIISIPLTETNKTSGVPGNRPGS 1178
>AB011088-1|BAA25442.3| 1382|Homo sapiens KIAA0516 protein protein.
Length = 1382
Score = 95.9 bits (228), Expect = 8e-19
Identities = 59/220 (26%), Positives = 111/220 (50%), Gaps = 6/220 (2%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + S+V + ++ L + ++ I + + V L +G +A++ R
Sbjct: 1032 TMWLGAQNGCLYVHSSVA-QWRKCLHSIKLKDSILSIVHVKGIVLVALADGTLAIFHRGV 1090
Query: 730 DDSWALQEPLAIELGDKPVH---CLLPVDGILYATCARRVFAINALTAEIMRILELKSDG 786
D W L ++LG +P H C+ V ++ +++ + +I + +
Sbjct: 1091 DGQWDLSNYHLLDLG-RPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRK 1149
Query: 787 DRTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYV 845
+ V+ LA G G+W + + + LYHA T++HLQ++DI V+K +G + G +
Sbjct: 1150 ESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRI 1209
Query: 846 SALLASQGLLWVGTTAGVSVTVPLPKLEGLPLVGGHIAGS 885
+AL+ S LWVGT GV +++PL + V G+ GS
Sbjct: 1210 TALMVSCNRLWVGTGNGVIISIPLTETNKTSGVPGNRPGS 1249
>AL031717-1|CAM26394.1| 1336|Homo sapiens mitogen-activated protein
kinase 8 interacting protein 3 protein.
Length = 1336
Score = 93.9 bits (223), Expect = 3e-18
Identities = 58/203 (28%), Positives = 101/203 (49%), Gaps = 4/203 (1%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + SAV K+ L + +V + + + V L +G +A++ R
Sbjct: 970 TMWLGAQNGWLYVHSAVANWKK-CLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGE 1028
Query: 730 DDSWALQEPLAIELGDK--PVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGD 787
D W L ++LG + C+ V ++ +V I T +I + + +
Sbjct: 1029 DGQWDLSNYHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRE 1088
Query: 788 RTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYVS 846
V+ LA G G+W + + + LYHA T +HLQ++DI V+K +G + G ++
Sbjct: 1089 SQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRIT 1148
Query: 847 ALLASQGLLWVGTTAGVSVTVPL 869
ALL + LWVGT GV +++PL
Sbjct: 1149 ALLVAGSRLWVGTGNGVVISIPL 1171
>AL031710-1|CAM26364.1| 1336|Homo sapiens mitogen-activated protein
kinase 8 interacting protein 3 protein.
Length = 1336
Score = 93.9 bits (223), Expect = 3e-18
Identities = 58/203 (28%), Positives = 101/203 (49%), Gaps = 4/203 (1%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + SAV K+ L + +V + + + V L +G +A++ R
Sbjct: 970 TMWLGAQNGWLYVHSAVANWKK-CLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGE 1028
Query: 730 DDSWALQEPLAIELGDK--PVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGD 787
D W L ++LG + C+ V ++ +V I T +I + + +
Sbjct: 1029 DGQWDLSNYHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRE 1088
Query: 788 RTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYVS 846
V+ LA G G+W + + + LYHA T +HLQ++DI V+K +G + G ++
Sbjct: 1089 SQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRIT 1148
Query: 847 ALLASQGLLWVGTTAGVSVTVPL 869
ALL + LWVGT GV +++PL
Sbjct: 1149 ALLVAGSRLWVGTGNGVVISIPL 1171
>AB028989-1|BAA83018.2| 1346|Homo sapiens KIAA1066 protein protein.
Length = 1346
Score = 93.9 bits (223), Expect = 3e-18
Identities = 58/203 (28%), Positives = 101/203 (49%), Gaps = 4/203 (1%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + SAV K+ L + +V + + + V L +G +A++ R
Sbjct: 980 TMWLGAQNGWLYVHSAVANWKK-CLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGE 1038
Query: 730 DDSWALQEPLAIELGDK--PVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGD 787
D W L ++LG + C+ V ++ +V I T +I + + +
Sbjct: 1039 DGQWDLSNYHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRE 1098
Query: 788 RTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYVS 846
V+ LA G G+W + + + LYHA T +HLQ++DI V+K +G + G ++
Sbjct: 1099 SQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRIT 1158
Query: 847 ALLASQGLLWVGTTAGVSVTVPL 869
ALL + LWVGT GV +++PL
Sbjct: 1159 ALLVAGSRLWVGTGNGVVISIPL 1181
>DQ847274-1|ABH10140.1| 914|Homo sapiens epithelial cell
transforming sequence 2 oncogene protein splice variant
b protein.
Length = 914
Score = 93.5 bits (222), Expect = 4e-18
Identities = 56/174 (32%), Positives = 85/174 (48%), Gaps = 6/174 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPA---ILNASKIQTLFHRLPDIL 175
Q R V + +E++YV L ++ ++ PLEE IL +I+T+F +PDI
Sbjct: 450 QSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIF 509
Query: 176 QCHLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H + L D WD + IG++FL +SK +V Y F+N F ++ E K+
Sbjct: 510 DVHTKIKDDLEDLIVNWDESKSIGDIFLK-YSKDLV-KTYPPFVNFFEMSKETIIKCEKQ 567
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K F K+ Q R S L+++PVQR P + L DL KHT + D+
Sbjct: 568 KPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDK 621
>BC112086-1|AAI12087.1| 883|Homo sapiens epithelial cell
transforming sequence 2 oncogene protein.
Length = 883
Score = 93.5 bits (222), Expect = 4e-18
Identities = 56/174 (32%), Positives = 85/174 (48%), Gaps = 6/174 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPA---ILNASKIQTLFHRLPDIL 175
Q R V + +E++YV L ++ ++ PLEE IL +I+T+F +PDI
Sbjct: 419 QSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIF 478
Query: 176 QCHLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H + L D WD + IG++FL +SK +V Y F+N F ++ E K+
Sbjct: 479 DVHTKIKDDLEDLIVNWDESKSIGDIFLK-YSKDLV-KTYPPFVNFFEMSKETIIKCEKQ 536
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K F K+ Q R S L+++PVQR P + L DL KHT + D+
Sbjct: 537 KPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDK 590
>AY376439-1|AAQ83675.1| 882|Homo sapiens epithelial cell
transforming 2 protein.
Length = 882
Score = 93.5 bits (222), Expect = 4e-18
Identities = 56/174 (32%), Positives = 85/174 (48%), Gaps = 6/174 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPA---ILNASKIQTLFHRLPDIL 175
Q R V + +E++YV L ++ ++ PLEE IL +I+T+F +PDI
Sbjct: 418 QSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIF 477
Query: 176 QCHLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H + L D WD + IG++FL +SK +V Y F+N F ++ E K+
Sbjct: 478 DVHTKIKDDLEDLIVNWDESKSIGDIFLK-YSKDLV-KTYPPFVNFFEMSKETIIKCEKQ 535
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K F K+ Q R S L+++PVQR P + L DL KHT + D+
Sbjct: 536 KPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDK 589
>AY236487-1|AAP74807.1| 766|Homo sapiens proliferation-inducing
gene 6 protein.
Length = 766
Score = 93.5 bits (222), Expect = 4e-18
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 6/204 (2%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + S+V + ++ L + ++ I + + V L +G +A++ R
Sbjct: 403 TMWLGAQNGCLYVHSSVA-QWRKCLHSIKLKDSILSIVHVKGIVLVALADGTLAIFHRGV 461
Query: 730 DDSWALQEPLAIELGDKPVH---CLLPVDGILYATCARRVFAINALTAEIMRILELKSDG 786
D W L ++LG +P H C+ V ++ +++ + +I + +
Sbjct: 462 DGQWDLSNYHLLDLG-RPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRK 520
Query: 787 DRTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYV 845
+ V+ LA G G+W + + + LYHA T++HLQ++DI V+K +G + G +
Sbjct: 521 ESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRI 580
Query: 846 SALLASQGLLWVGTTAGVSVTVPL 869
+AL+ S LWVGT GV +++PL
Sbjct: 581 TALMVSCNRLWVGTGNGVIISIPL 604
>AK023267-1|BAB14498.1| 798|Homo sapiens protein ( Homo sapiens
cDNA FLJ13205 fis, clone NT2RP3004534, highly similar to
Mouse oncogene (ect2) mRNA. ).
Length = 798
Score = 93.5 bits (222), Expect = 4e-18
Identities = 56/174 (32%), Positives = 85/174 (48%), Gaps = 6/174 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPA---ILNASKIQTLFHRLPDIL 175
Q R V + +E++YV L ++ ++ PLEE IL +I+T+F +PDI
Sbjct: 419 QSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIF 478
Query: 176 QCHLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H + L D WD + IG++FL +SK +V Y F+N F ++ E K+
Sbjct: 479 DVHTKIKDDLEDLIVNWDESKSIGDIFLK-YSKDLV-KTYPPFVNFFEMSKETIIKCEKQ 536
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K F K+ Q R S L+++PVQR P + L DL KHT + D+
Sbjct: 537 KPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDK 590
>AF542172-1|AAQ11383.1| 508|Homo sapiens HLC-6 protein.
Length = 508
Score = 93.5 bits (222), Expect = 4e-18
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 6/204 (2%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + S+V + ++ L + ++ I + + V L +G +A++ R
Sbjct: 145 TMWLGAQNGCLYVHSSVA-QWRKCLHSIKLKDSILSIVHVKGIVLVALADGTLAIFHRGV 203
Query: 730 DDSWALQEPLAIELGDKPVH---CLLPVDGILYATCARRVFAINALTAEIMRILELKSDG 786
D W L ++LG +P H C+ V ++ +++ + +I + +
Sbjct: 204 DGQWDLSNYHLLDLG-RPHHSIRCMTVVHDKVWCGYRNKIYVVQPKAMKIEKSFDAHPRK 262
Query: 787 DRTVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYV 845
+ V+ LA G G+W + + + LYHA T++HLQ++DI V+K +G + G +
Sbjct: 263 ESQVRQLAWVGDGVWVSIRLDSTLRLYHAHTYQHLQDVDIEPYVSKMLGTGKLGFSFVRI 322
Query: 846 SALLASQGLLWVGTTAGVSVTVPL 869
+AL+ S LWVGT GV +++PL
Sbjct: 323 TALMVSCNRLWVGTGNGVIISIPL 346
>AK092020-1|BAC03792.1| 633|Homo sapiens protein ( Homo sapiens
cDNA FLJ34701 fis, clone MESAN2002724, weakly similar to
Rho guanine nucleotide exchange factor (GEF) 10. ).
Length = 633
Score = 89.0 bits (211), Expect = 9e-17
Identities = 38/87 (43%), Positives = 59/87 (67%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q+ RRH++ +I+ SE SYV +L+R++ DY+ PL E P L+A K Q +F R+ +IL CH
Sbjct: 92 QVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCH 151
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSA 205
F+ AL+ WD EKIG++F+++
Sbjct: 152 SMFQIALSSRVAEWDSTEKIGDLFVAS 178
Score = 53.2 bits (122), Expect = 5e-06
Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 20/231 (8%)
Query: 354 KRHLLRQDDLLQMEFNQSGGLSKCKPRRLLLLNDLVVCVSVGAGG----DDAERLG---- 405
+R LL + L + + G L K K RR+ LLND++VC ++ G LG
Sbjct: 242 QRQLLLCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKGQLEISSLVPLGPKYV 301
Query: 406 LKW--AHP-VQDVEVLDTGTSPTLSRVLAQGMXXXXXXXXXXXXXQMSTSTGDSLCGEMS 462
+KW A P VQ VEV G + VL Q ++ L E+
Sbjct: 302 VKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQNKVYLGP-PRLFQELQ 360
Query: 463 TLMHDYETVSRMADLAASLKTPYPELAPEMFKTLLQSIQQSIQKKDDEMAWVDSCCLQLR 522
L D V ++ L ++L Y L + + ++Q+ ++ K++E+ + C L+L
Sbjct: 361 DLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLL 420
Query: 523 IRGREE--------ALTFRANEPGARLGWXXXXXXXXXXXXXXNSPAWRVP 565
+ G+ + + F P +++ W N P W P
Sbjct: 421 LPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCP 471
>X02596-1|CAA26441.1| 1271|Homo sapiens bcr protein.
Length = 1271
Score = 87.4 bits (207), Expect = 3e-16
Identities = 53/175 (30%), Positives = 94/175 (53%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 499 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 558
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
F L Q W +++G++F S+ L VY F++N+ VAME+A+ + +
Sbjct: 559 EFYDGLFPRVQQWSHQQRVGDLFQKLASQ---LGVYRAFVDNYGVAMEMAEKCCQANAQF 615
Query: 240 ADFFK-VKQISAHD------RLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
A+ + ++ S D + S L+ KPV R + + L DLLKHTP H D
Sbjct: 616 AEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPD 670
>U07000-3|AAB60389.1| 889|Homo sapiens breakpoint cluster region
protein protein.
Length = 889
Score = 87.4 bits (207), Expect = 3e-16
Identities = 53/175 (30%), Positives = 94/175 (53%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 117 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 176
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
F L Q W +++G++F S+ L VY F++N+ VAME+A+ + +
Sbjct: 177 EFYDGLFPRVQQWSHQQRVGDLFQKLASQ---LGVYRAFVDNYGVAMEMAEKCCQANAQF 233
Query: 240 ADFFK-VKQISAHD------RLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
A+ + ++ S D + S L+ KPV R + + L DLLKHTP H D
Sbjct: 234 AEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPD 288
>U07000-2|AAB60390.1| 936|Homo sapiens breakpoint cluster region
protein protein.
Length = 936
Score = 87.4 bits (207), Expect = 3e-16
Identities = 53/175 (30%), Positives = 94/175 (53%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 164 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 223
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
F L Q W +++G++F S+ L VY F++N+ VAME+A+ + +
Sbjct: 224 EFYDGLFPRVQQWSHQQRVGDLFQKLASQ---LGVYRAFVDNYGVAMEMAEKCCQANAQF 280
Query: 240 ADFFK-VKQISAHD------RLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
A+ + ++ S D + S L+ KPV R + + L DLLKHTP H D
Sbjct: 281 AEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPD 335
>U07000-1|AAB60388.1| 1271|Homo sapiens breakpoint cluster region
protein protein.
Length = 1271
Score = 87.4 bits (207), Expect = 3e-16
Identities = 53/175 (30%), Positives = 94/175 (53%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 499 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 558
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
F L Q W +++G++F S+ L VY F++N+ VAME+A+ + +
Sbjct: 559 EFYDGLFPRVQQWSHQQRVGDLFQKLASQ---LGVYRAFVDNYGVAMEMAEKCCQANAQF 615
Query: 240 ADFFK-VKQISAHD------RLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
A+ + ++ S D + S L+ KPV R + + L DLLKHTP H D
Sbjct: 616 AEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPD 670
>M15025-1|AAA35594.1| 693|Homo sapiens protein ( Human BCR/ABL mRNA
(product of translocation t(22q11;9q34)), 5' end. ).
Length = 693
Score = 87.4 bits (207), Expect = 3e-16
Identities = 53/175 (30%), Positives = 94/175 (53%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 499 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 558
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
F L Q W +++G++F S+ L VY F++N+ VAME+A+ + +
Sbjct: 559 EFYDGLFPRVQQWSHQQRVGDLFQKLASQ---LGVYRAFVDNYGVAMEMAEKCCQANAQF 615
Query: 240 ADFFK-VKQISAHD------RLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
A+ + ++ S D + S L+ KPV R + + L DLLKHTP H D
Sbjct: 616 AEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPD 670
>AB209991-1|BAE06073.1| 1287|Homo sapiens BCR variant protein
protein.
Length = 1287
Score = 87.4 bits (207), Expect = 3e-16
Identities = 53/175 (30%), Positives = 94/175 (53%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 515 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 574
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
F L Q W +++G++F S+ L VY F++N+ VAME+A+ + +
Sbjct: 575 EFYDGLFPRVQQWSHQQRVGDLFQKLASQ---LGVYRAFVDNYGVAMEMAEKCCQANAQF 631
Query: 240 ADFFK-VKQISAHD------RLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
A+ + ++ S D + S L+ KPV R + + L DLLKHTP H D
Sbjct: 632 AEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPD 686
>AE006639-4|AAK61290.1| 1342|Homo sapiens similar to sperm specifc
protein protein.
Length = 1342
Score = 86.6 bits (205), Expect = 5e-16
Identities = 59/209 (28%), Positives = 101/209 (48%), Gaps = 10/209 (4%)
Query: 670 TVWLGTEDKKIIIFSAVEPEKQEKLAEVPTVAAVTQIRYHCDAMFVGLTNGRVAVYRRNH 729
T+WLG ++ + + SAV K+ L + +V + + + V L +G +A++ R
Sbjct: 970 TMWLGAQNGWLYVHSAVANWKK-CLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGE 1028
Query: 730 DDSWALQEPLAIELGDK--PVHCLLPVDGILYATCARRVFAINALTAEIMRILELKSDGD 787
D W L ++LG + C+ V ++ +V I T +I + + D
Sbjct: 1029 DGQWDLSNYHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEATMTPQKSFD 1088
Query: 788 R------TVKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGS 840
V+ LA G G+W + + + LYHA T +HLQ++DI V+K +G + G
Sbjct: 1089 AHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGF 1148
Query: 841 KPAYVSALLASQGLLWVGTTAGVSVTVPL 869
++ALL + LWVGT GV +++PL
Sbjct: 1149 SFVRITALLVAGSRLWVGTGNGVVISIPL 1177
>U01147-1|AAC50063.1| 859|Homo sapiens guanine nucleotide
regulatory protein protein.
Length = 859
Score = 84.6 bits (200), Expect = 2e-15
Identities = 53/175 (30%), Positives = 89/175 (50%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ + SE Y+ L+ L+ K K +S +L +I+T+F+++ DI + H
Sbjct: 92 RKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHK 151
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS-- 237
F L Q WD +G +F S+ L VY F++N+ VA+E A+ S+ +
Sbjct: 152 EFYDNLCPKVQQWDSQVTMGHLFQKLASQ---LGVYKAFVDNYKVALETAEKCSQSNNQF 208
Query: 238 -ALADFFKVK----QISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+++ KVK +H ++ L+ KP+ R + + L DLLKHTP H D
Sbjct: 209 QKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPD 263
>L19704-1|AAC37519.1| 822|Homo sapiens ABR protein.
Length = 822
Score = 84.6 bits (200), Expect = 2e-15
Identities = 53/175 (30%), Positives = 89/175 (50%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ + SE Y+ L+ L+ K K +S +L +I+T+F+++ DI + H
Sbjct: 55 RKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHK 114
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS-- 237
F L Q WD +G +F S+ L VY F++N+ VA+E A+ S+ +
Sbjct: 115 EFYDNLCPKVQQWDSQVTMGHLFQKLASQ---LGVYKAFVDNYKVALETAEKCSQSNNQF 171
Query: 238 -ALADFFKVK----QISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+++ KVK +H ++ L+ KP+ R + + L DLLKHTP H D
Sbjct: 172 QKISEELKVKGPKDSKDSHTSVTMEALLYKPIDRVTRSTLVLHDLLKHTPVDHPD 226
>Y00661-1|CAA68676.1| 1227|Homo sapiens protein ( Human bcr mRNA
(break point cluster gene). ).
Length = 1227
Score = 84.2 bits (199), Expect = 2e-15
Identities = 52/175 (29%), Positives = 93/175 (53%), Gaps = 12/175 (6%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 499 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 558
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
L Q W +++G++F S+ L VY F++N+ VAME+A+ + +
Sbjct: 559 ESYDGLFPRVQQWSHQQRVGDLFQKLASQ---LGVYRAFVDNYGVAMEMAEKCCQANAQF 615
Query: 240 ADFFK-VKQISAHD------RLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
A+ + ++ S D + S L+ KPV R + + L DLLKHTP H D
Sbjct: 616 AEISENLRARSNKDAKDPTTKNSLETLLYKPVDRVTRSTLVLHDLLKHTPASHPD 670
>AK126882-1|BAC86734.1| 362|Homo sapiens protein ( Homo sapiens
cDNA FLJ44934 fis, clone BRAMY3017920, highly similar
to Active breakpoint cluster region-related protein. ).
Length = 362
Score = 76.2 bits (179), Expect = 7e-13
Identities = 45/146 (30%), Positives = 74/146 (50%), Gaps = 10/146 (6%)
Query: 149 KPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADCAQTWDRDEKIGEVFLSAFSK 208
K +S +L +I+T+F+++ DI + H F L Q WD +G +F S+
Sbjct: 5 KATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ 64
Query: 209 AVVLDVYSDFINNFSVAMELAKMESKRKS---ALADFFKVK----QISAHDRLSFFGLMV 261
L VY F++N+ VA+E A+ S+ + +++ KVK +H ++ L+
Sbjct: 65 ---LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEALLY 121
Query: 262 KPVQRFPQFIMFLQDLLKHTPPGHAD 287
KP+ R + + L DLLKHTP H D
Sbjct: 122 KPIDRVTRSTLVLHDLLKHTPVDHPD 147
>DQ904331-1|ABI98401.1| 835|Homo sapiens lung specific F-box and DH
domain containing protein protein.
Length = 835
Score = 74.5 bits (175), Expect = 2e-12
Identities = 52/172 (30%), Positives = 85/172 (49%), Gaps = 7/172 (4%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLE---ESSPAILNASKIQTLFHRLPDILQC 177
+R VV ++ SE YV L+ + + Y PL+ S+ AIL+A+ IQ +F + IL
Sbjct: 497 KRARVVRELLQSERKYVQILEIVRDVYVAPLKAALSSNRAILSAANIQIIFCDILQILSL 556
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
+ F L D Q WD +GE+ S+ L+ Y++F NN+ V ++ + +
Sbjct: 557 NRQFLDNLRDRLQEWDPAHCVGEIVTKFGSQ---LNTYTNFFNNYPVILKTIEKCREMIP 613
Query: 238 ALADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
A F K + + LS L++ P +RF +++ L + HTP H DR
Sbjct: 614 AFRTFLKRHDKTIVTKMLSLPELLLYPSRRFEEYLNLLYAVRLHTPAEHVDR 665
>AM491362-1|CAM33012.1| 585|Homo sapiens bcr-abl1 e6a2 chimeric
protein protein.
Length = 585
Score = 64.5 bits (150), Expect = 2e-09
Identities = 33/111 (29%), Positives = 64/111 (57%), Gaps = 5/111 (4%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 224 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 283
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAK 230
F L Q W +++G++F S+ L VY ++N+ VAME+A+
Sbjct: 284 EFYDGLFPRVQQWSHQQRVGDLFQKLASQ---LGVYRASVDNYGVAMEMAE 331
>AL031718-1|CAB72318.1| 552|Homo sapiens c371H6.1 (KIAA0516
protein) protein.
Length = 552
Score = 63.3 bits (147), Expect = 5e-09
Identities = 32/81 (39%), Positives = 49/81 (60%), Gaps = 1/81 (1%)
Query: 790 VKYLAHSGVGLWTAFSDSTFVSLYHAETFEHLQNIDIAADVAKTIG-ARDGSKPAYVSAL 848
V+ LA G G+W + + + LYHA T +HLQ++DI V+K +G + G ++AL
Sbjct: 307 VRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKLGFSFVRITAL 366
Query: 849 LASQGLLWVGTTAGVSVTVPL 869
L + LWVGT GV +++PL
Sbjct: 367 LVAGSRLWVGTGNGVVISIPL 387
>AK057294-1|BAB71413.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ32732 fis, clone TESTI2001141, highly similar to
Rattus norvegicus actin-filament binding protein Frabin
mRNA. ).
Length = 766
Score = 60.5 bits (140), Expect = 4e-08
Identities = 50/174 (28%), Positives = 82/174 (47%), Gaps = 13/174 (7%)
Query: 121 RRRHVVA-AIIHSENSYVATLQRLVND-YKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++ H +A ++ +E +YV L L Y K LEE++ A + +F + I H
Sbjct: 205 QKLHKIANELLLTERAYVNRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFH 264
Query: 179 LHFRTA-LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR-- 235
F L Q W+ +IG++ A L +Y +++ F AMEL K ++R
Sbjct: 265 SKFLLPELEKRMQEWETTPRIGDILQKL---APFLKMYGEYVKGFDNAMELVKNMTERIP 321
Query: 236 --KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
KS + + K K + L+ M++PVQR P++ M L+D L+ PP D
Sbjct: 322 QFKSVVEEIQKQKICGS---LTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLD 372
>Z85987-1|CAI42222.1| 961|Homo sapiens FYVE, RhoGEF and PH domain
containing 1 (faciogenital dysplasia) protein.
Length = 961
Score = 59.7 bits (138), Expect = 6e-08
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 7/174 (4%)
Query: 118 VQLRRRHVVAAIIHSENSYVATLQRLVNDY-KKPLEES-SPAILNASKIQTLFHRLPDIL 175
VQ + H+ ++ +E +YV+ L L + + LEE+ + + A + +F + I
Sbjct: 370 VQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIY 429
Query: 176 QCHLHFRTA-LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESK 234
H F L + WDR +IG++ A L +Y +++ NF A+EL ++
Sbjct: 430 CFHQQFLLPELEKRMEEWDRYPRIGDILQKL---APFLKMYGEYVKNFDRAVELVNTWTE 486
Query: 235 RKSALADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
R + +V++ A L+ M++PVQR P++ + L+D L P G D
Sbjct: 487 RSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPD 540
>U11690-1|AAA57004.1| 961|Homo sapiens FGD1 protein.
Length = 961
Score = 59.7 bits (138), Expect = 6e-08
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 7/174 (4%)
Query: 118 VQLRRRHVVAAIIHSENSYVATLQRLVNDY-KKPLEES-SPAILNASKIQTLFHRLPDIL 175
VQ + H+ ++ +E +YV+ L L + + LEE+ + + A + +F + I
Sbjct: 370 VQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIY 429
Query: 176 QCHLHFRTA-LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESK 234
H F L + WDR +IG++ A L +Y +++ NF A+EL ++
Sbjct: 430 CFHQQFLLPELEKRMEEWDRYPRIGDILQKL---APFLKMYGEYVKNFDRAVELVNTWTE 486
Query: 235 RKSALADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
R + +V++ A L+ M++PVQR P++ + L+D L P G D
Sbjct: 487 RSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPD 540
>BC034530-1|AAH34530.1| 961|Homo sapiens FYVE, RhoGEF and PH domain
containing 1 (faciogenital dysplasia) protein.
Length = 961
Score = 59.7 bits (138), Expect = 6e-08
Identities = 46/174 (26%), Positives = 83/174 (47%), Gaps = 7/174 (4%)
Query: 118 VQLRRRHVVAAIIHSENSYVATLQRLVNDY-KKPLEES-SPAILNASKIQTLFHRLPDIL 175
VQ + H+ ++ +E +YV+ L L + + LEE+ + + A + +F + I
Sbjct: 370 VQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIY 429
Query: 176 QCHLHFRTA-LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESK 234
H F L + WDR +IG++ A L +Y +++ NF A+EL ++
Sbjct: 430 CFHQQFLLPELEKRMEEWDRYPRIGDILQKL---APFLKMYGEYVKNFDRAVELVNTWTE 486
Query: 235 RKSALADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
R + +V++ A L+ M++PVQR P++ + L+D L P G D
Sbjct: 487 RSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPD 540
>AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 58.8 bits (136), Expect = 1e-07
Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 9/157 (5%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
VV I+ +E +YV L+ +V DY + + + L + LF + DI HF +
Sbjct: 117 VVQEILETERTYVQDLKSIVEDYLDCIRDQTKLPLGTEERSALFGNIQDI----YHFNSE 172
Query: 185 LADCAQTWDRDE-KIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFF 243
L + + D I E F+ SK+ +Y+ + N+ ++ + E R LA FF
Sbjct: 173 LLQDLENCENDPVAIAECFV---SKSEEFHIYTQYCTNYPRSVAVL-TECMRNKILAKFF 228
Query: 244 KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
+ +Q + L ++KPVQR ++ + L ++ H
Sbjct: 229 RERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENH 265
>AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 58.8 bits (136), Expect = 1e-07
Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 9/157 (5%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
VV I+ +E +YV L+ +V DY + + + L + LF + DI HF +
Sbjct: 117 VVQEILETERTYVQDLKSIVEDYLDCIRDQTKLPLGTEERSALFGNIQDI----YHFNSE 172
Query: 185 LADCAQTWDRDE-KIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFF 243
L + + D I E F+ SK+ +Y+ + N+ ++ + E R LA FF
Sbjct: 173 LLQDLENCENDPVAIAECFV---SKSEEFHIYTQYCTNYPRSVAVL-TECMRNKILAKFF 228
Query: 244 KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
+ +Q + L ++KPVQR ++ + L ++ H
Sbjct: 229 RERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENH 265
>AL445192-1|CAI39886.1| 1659|Homo sapiens RP11-269H4.1 protein.
Length = 1659
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 9/205 (4%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDY----KKPLEESSPAILNASKIQTLFHRLPD 173
QLR R V+ I+ +E YV TL+ L + + ++ + +S L ++ LF + D
Sbjct: 46 QLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIED 105
Query: 174 ILQCHLHFRTALADCAQTWDRDE-KIGEVFLSAFSKAVVLDVY-SDFINNFSVAMELAKM 231
IL+ H F AL C + + ++G VFL K V + Y S+ + +EL K+
Sbjct: 106 ILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKI 165
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXX 291
+ R L+ + + L G ++ P+QR ++ + L++L K TP H D
Sbjct: 166 PTVRAFLLSCMLLGGRKTTDIPLE--GYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAV 223
Query: 292 XXXXXXXXXXXXXXXXXKRDAERTQ 316
KR E+ +
Sbjct: 224 QSALQAMKTVCSNINETKRQMEKLE 248
>AL133342-1|CAI23274.1| 1659|Homo sapiens RP11-269H4.1 protein.
Length = 1659
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 9/205 (4%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDY----KKPLEESSPAILNASKIQTLFHRLPD 173
QLR R V+ I+ +E YV TL+ L + + ++ + +S L ++ LF + D
Sbjct: 46 QLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIED 105
Query: 174 ILQCHLHFRTALADCAQTWDRDE-KIGEVFLSAFSKAVVLDVY-SDFINNFSVAMELAKM 231
IL+ H F AL C + + ++G VFL K V + Y S+ + +EL K+
Sbjct: 106 ILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKI 165
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXX 291
+ R L+ + + L G ++ P+QR ++ + L++L K TP H D
Sbjct: 166 PTVRAFLLSCMLLGGRKTTDIPLE--GYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAV 223
Query: 292 XXXXXXXXXXXXXXXXXKRDAERTQ 316
KR E+ +
Sbjct: 224 QSALQAMKTVCSNINETKRQMEKLE 248
>AL035106-1|CAI43186.1| 1659|Homo sapiens RP11-269H4.1 protein.
Length = 1659
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 9/205 (4%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDY----KKPLEESSPAILNASKIQTLFHRLPD 173
QLR R V+ I+ +E YV TL+ L + + ++ + +S L ++ LF + D
Sbjct: 46 QLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIED 105
Query: 174 ILQCHLHFRTALADCAQTWDRDE-KIGEVFLSAFSKAVVLDVY-SDFINNFSVAMELAKM 231
IL+ H F AL C + + ++G VFL K V + Y S+ + +EL K+
Sbjct: 106 ILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKI 165
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXX 291
+ R L+ + + L G ++ P+QR ++ + L++L K TP H D
Sbjct: 166 PTVRAFLLSCMLLGGRKTTDIPLE--GYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAV 223
Query: 292 XXXXXXXXXXXXXXXXXKRDAERTQ 316
KR E+ +
Sbjct: 224 QSALQAMKTVCSNINETKRQMEKLE 248
>AJ320261-1|CAC86401.1| 1659|Homo sapiens P-Rex1 protein protein.
Length = 1659
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 9/205 (4%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDY----KKPLEESSPAILNASKIQTLFHRLPD 173
QLR R V+ I+ +E YV TL+ L + + ++ + +S L ++ LF + D
Sbjct: 46 QLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIED 105
Query: 174 ILQCHLHFRTALADCAQTWDRDE-KIGEVFLSAFSKAVVLDVY-SDFINNFSVAMELAKM 231
IL+ H F AL C + + ++G VFL K V + Y S+ + +EL K+
Sbjct: 106 ILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKI 165
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXX 291
+ R L+ + + L G ++ P+QR ++ + L++L K TP H D
Sbjct: 166 PTVRAFLLSCMLLGGRKTTDIPLE--GYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAV 223
Query: 292 XXXXXXXXXXXXXXXXXKRDAERTQ 316
KR E+ +
Sbjct: 224 QSALQAMKTVCSNINETKRQMEKLE 248
>AB037836-1|BAA92653.2| 1621|Homo sapiens KIAA1415 protein protein.
Length = 1621
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/205 (25%), Positives = 89/205 (43%), Gaps = 9/205 (4%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDY----KKPLEESSPAILNASKIQTLFHRLPD 173
QLR R V+ I+ +E YV TL+ L + + ++ + +S L ++ LF + D
Sbjct: 8 QLRLRLCVLNEILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIED 67
Query: 174 ILQCHLHFRTALADCAQTWDRDE-KIGEVFLSAFSKAVVLDVY-SDFINNFSVAMELAKM 231
IL+ H F AL C + + ++G VFL K V + Y S+ + +EL K+
Sbjct: 68 ILEVHKDFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKI 127
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXX 291
+ R L+ + + L G ++ P+QR ++ + L++L K TP H D
Sbjct: 128 PTVRAFLLSCMLLGGRKTTDIPLE--GYLLSPIQRICKYPLLLKELAKRTPGKHPDHPAV 185
Query: 292 XXXXXXXXXXXXXXXXXKRDAERTQ 316
KR E+ +
Sbjct: 186 QSALQAMKTVCSNINETKRQMEKLE 210
>AK024429-1|BAB15719.1| 1430|Homo sapiens FLJ00018 protein protein.
Length = 1430
Score = 57.2 bits (132), Expect = 3e-07
Identities = 42/164 (25%), Positives = 75/164 (45%), Gaps = 8/164 (4%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R V I+ +E +YV L+ +V DY PL + L+ ++ TLF + DI +
Sbjct: 146 RLERVAREIVETERAYVRDLRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYE---- 201
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
F + L + + I E F+ ++ D+Y+ + N+ ++ L + E A
Sbjct: 202 FSSELLEDLENSSSAGGIAECFV---QRSEDFDIYTLYCMNYPSSLALLR-ELSLSPPAA 257
Query: 241 DFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPG 284
+ + +Q L ++KPVQR ++ + LQ+L KH G
Sbjct: 258 LWLQERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEG 301
>BC129953-1|AAI29954.1| 1219|Homo sapiens PLEKHG3 protein protein.
Length = 1219
Score = 56.4 bits (130), Expect = 6e-07
Identities = 39/156 (25%), Positives = 71/156 (45%), Gaps = 8/156 (5%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
VV I+ +E YV L+ +V DY + ++ P +L ++ LF + +I +
Sbjct: 97 VVREIVETERMYVQDLRSIVEDYLLKIIDT-PGLLKPEQVSALFGNIENIYALNSQLLRD 155
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L C + F+ ++ D+Y+ + NN+ ++ A E R A FF+
Sbjct: 156 LDSCNSD---PVAVASCFVE---RSQEFDIYTQYCNNYPNSVA-ALTECMRDKQQAKFFR 208
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
+Q L ++KPVQR ++ + LQ++ KH
Sbjct: 209 DRQELLQHSLPLGSYLLKPVQRILKYHLLLQEIAKH 244
>AF249745-1|AAF79955.1| 720|Homo sapiens RhoGEF protein.
Length = 720
Score = 56.4 bits (130), Expect = 6e-07
Identities = 39/168 (23%), Positives = 83/168 (49%), Gaps = 7/168 (4%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y + + + + + +++T+F + DI +C F
Sbjct: 252 RTNVINEILSTERDYIKHLRDICEGYVRQCRKRAD-MFSEEQLRTIFGNIEDIYRCQKAF 310
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNF-SVAMELAKMESKRKSAL 239
AL Q ++R+ + E+ +YS++ NN + +EL+++ +K +
Sbjct: 311 VKALE---QRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRL-TKLSKYV 366
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
F + + +S G ++ PVQ+ ++ + L +LLK+T P H D
Sbjct: 367 YFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRD 414
>AC009477-1|AAX93134.1| 547|Homo sapiens unknown protein.
Length = 547
Score = 56.4 bits (130), Expect = 6e-07
Identities = 39/168 (23%), Positives = 83/168 (49%), Gaps = 7/168 (4%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y + + + + + +++T+F + DI +C F
Sbjct: 142 RTNVINEILSTERDYIKHLRDICEGYVRQCRKRAD-MFSEEQLRTIFGNIEDIYRCQKAF 200
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNF-SVAMELAKMESKRKSAL 239
AL Q ++R+ + E+ +YS++ NN + +EL+++ +K +
Sbjct: 201 VKALE---QRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRL-TKLSKYV 256
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
F + + +S G ++ PVQ+ ++ + L +LLK+T P H D
Sbjct: 257 YFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRD 304
>AB042199-1|BAB11941.1| 619|Homo sapiens APC-stimulated guanine
nucleotide exchange factor protein.
Length = 619
Score = 56.4 bits (130), Expect = 6e-07
Identities = 39/168 (23%), Positives = 83/168 (49%), Gaps = 7/168 (4%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y + + + + + +++T+F + DI +C F
Sbjct: 214 RTNVINEILSTERDYIKHLRDICEGYVRQCRKRAD-MFSEEQLRTIFGNIEDIYRCQKAF 272
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNF-SVAMELAKMESKRKSAL 239
AL Q ++R+ + E+ +YS++ NN + +EL+++ +K +
Sbjct: 273 VKALE---QRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRL-TKLSKYV 328
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
F + + +S G ++ PVQ+ ++ + L +LLK+T P H D
Sbjct: 329 YFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRD 376
>AB029035-1|BAA83064.1| 694|Homo sapiens KIAA1112 protein protein.
Length = 694
Score = 56.4 bits (130), Expect = 6e-07
Identities = 39/168 (23%), Positives = 83/168 (49%), Gaps = 7/168 (4%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y + + + + + +++T+F + DI +C F
Sbjct: 309 RTNVINEILSTERDYIKHLRDICEGYVRQCRKRAD-MFSEEQLRTIFGNIEDIYRCQKAF 367
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNF-SVAMELAKMESKRKSAL 239
AL Q ++R+ + E+ +YS++ NN + +EL+++ +K +
Sbjct: 368 VKALE---QRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRL-TKLSKYV 423
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
F + + +S G ++ PVQ+ ++ + L +LLK+T P H D
Sbjct: 424 YFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRD 471
>BC075858-1|AAH75858.1| 1253|Homo sapiens PLEKHG2 protein protein.
Length = 1253
Score = 56.0 bits (129), Expect = 8e-07
Identities = 41/160 (25%), Positives = 74/160 (46%), Gaps = 8/160 (5%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V I+ +E +YV L+ +V DY PL + L+ ++ TLF + DI + F +
Sbjct: 2 VAREIVETERAYVRDLRSIVEDYLGPLLDGGVLGLSVEQVGTLFANIEDIYE----FSSE 57
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L + + I E F+ ++ D+Y+ + N+ ++ L + E A + +
Sbjct: 58 LLEDLENSSSAGGIAECFV---QRSEDFDIYTLYCMNYPSSLALLR-ELSLSPPAALWLQ 113
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPG 284
+Q L ++KPVQR ++ + LQ+L KH G
Sbjct: 114 ERQAQLRHSLPLQSFLLKPVQRILKYHLLLQELGKHWAEG 153
>AY508997-1|AAS82572.1| 979|Homo sapiens P-Rex2B protein.
Length = 979
Score = 55.6 bits (128), Expect = 1e-06
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 11/206 (5%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPD 173
QLR R V++ + +E YV TL+ LV+ + + + + + ++ + ++ LF + D
Sbjct: 20 QLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIED 79
Query: 174 ILQCHLHFRTALADCAQTW-DRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKME 232
IL H F + +C + +++G FL K +Y ++ +N A +L
Sbjct: 80 ILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDK---FRIYDEYCSNHEKAQKLLLEL 136
Query: 233 SKRKSALADFFKVKQISAHDRLS--FFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVX 290
+K ++ + + G +V P+QR ++ + L++LLK TP H+D
Sbjct: 137 NKIRTIRTFLLNCMLLGGRKNIDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAA 196
Query: 291 XXXXXXXXXXXXXXXXXXKRDAERTQ 316
KR E+ +
Sbjct: 197 VMEALQAMKAVCSNINEAKRQMEKLE 222
>AY508996-1|AAS82571.1| 1606|Homo sapiens P-Rex2 protein.
Length = 1606
Score = 55.6 bits (128), Expect = 1e-06
Identities = 45/206 (21%), Positives = 88/206 (42%), Gaps = 11/206 (5%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPD 173
QLR R V++ + +E YV TL+ LV+ + + + + + ++ + ++ LF + D
Sbjct: 20 QLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIED 79
Query: 174 ILQCHLHFRTALADCAQTW-DRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKME 232
IL H F + +C + +++G FL K +Y ++ +N A +L
Sbjct: 80 ILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDK---FRIYDEYCSNHEKAQKLLLEL 136
Query: 233 SKRKSALADFFKVKQISAHDRLS--FFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVX 290
+K ++ + + G +V P+QR ++ + L++LLK TP H+D
Sbjct: 137 NKIRTIRTFLLNCMLLGGRKNIDVPLEGYLVTPIQRICKYPLILKELLKRTPRKHSDYAA 196
Query: 291 XXXXXXXXXXXXXXXXXXKRDAERTQ 316
KR E+ +
Sbjct: 197 VMEALQAMKAVCSNINEAKRQMEKLE 222
>BC032429-1|AAH32429.1| 725|Homo sapiens FGD3 protein protein.
Length = 725
Score = 55.2 bits (127), Expect = 1e-06
Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 9/168 (5%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRT 183
H+ ++H+E +YV L L + L ++ + I +F + I + H F
Sbjct: 160 HIAQELLHTEETYVKRLHLLDQVFCTRLTDAG---IPPEVIMGIFSNISSIHRFHGQFLL 216
Query: 184 A--LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALAD 241
+ WD + ++G++ A L +Y +++ NF A+ L ++R D
Sbjct: 217 PELKTRITEEWDTNPRLGDILQKL---APFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKD 273
Query: 242 FF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
+++ L+ M++PVQR P++ + L+D LK P DR
Sbjct: 274 VIHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDR 321
>AK000004-1|BAA92229.1| 698|Homo sapiens FLJ00004 protein protein.
Length = 698
Score = 55.2 bits (127), Expect = 1e-06
Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 9/168 (5%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRT 183
H+ ++H+E +YV L L + L ++ + I +F + I + H F
Sbjct: 224 HIAQELLHTEETYVKRLHLLDQVFCTRLTDAG---IPPEVIMGIFSNISSIHRFHGQFLL 280
Query: 184 A--LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALAD 241
+ WD + ++G++ A L +Y +++ NF A+ L ++R D
Sbjct: 281 PELKTRITEEWDTNPRLGDILQKL---APFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKD 337
Query: 242 FF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
+++ L+ M++PVQR P++ + L+D LK P DR
Sbjct: 338 VIHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDR 385
>BC111054-1|AAI11055.1| 725|Homo sapiens FGD3 protein protein.
Length = 725
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 9/168 (5%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRT 183
H+ ++H+E +YV L L + L ++ + I +F + I + H F
Sbjct: 160 HIAQELLHTEETYVKRLHLLDQVFCTRLTDAG---IPPEVIMGIFSNISSIHRFHGQFLL 216
Query: 184 A--LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALAD 241
+ WD + ++G++ A L +Y +++ NF A+ L ++R D
Sbjct: 217 PELKTRITEEWDTNPRLGDILQKL---APFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKD 273
Query: 242 FF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
+++ L+ M++PVQR P++ + L+D LK P DR
Sbjct: 274 VVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDR 321
>AY211386-1|AAP20645.1| 634|Homo sapiens FGD3 protein.
Length = 634
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 9/168 (5%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRT 183
H+ ++H+E +YV L L + L ++ + I +F + I + H F
Sbjct: 160 HIAQELLHTEETYVKRLHLLDQVFCTRLTDAG---IPPEVIMGIFSNISSIHRFHGQFLL 216
Query: 184 A--LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALAD 241
+ WD + ++G++ A L +Y +++ NF A+ L ++R D
Sbjct: 217 PELKTRITEEWDTNPRLGDILQKL---APFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKD 273
Query: 242 FF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
+++ L+ M++PVQR P++ + L+D LK P DR
Sbjct: 274 VVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDR 321
>AL451065-1|CAI95107.1| 725|Homo sapiens FYVE, RhoGEF and PH domain
containing 3 protein.
Length = 725
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 9/168 (5%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRT 183
H+ ++H+E +YV L L + L ++ + I +F + I + H F
Sbjct: 160 HIAQELLHTEETYVKRLHLLDQVFCTRLTDAG---IPPEVIMGIFSNISSIHRFHGQFLL 216
Query: 184 A--LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALAD 241
+ WD + ++G++ A L +Y +++ NF A+ L ++R D
Sbjct: 217 PELKTRITEEWDTNPRLGDILQKL---APFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKD 273
Query: 242 FF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
+++ L+ M++PVQR P++ + L+D LK P DR
Sbjct: 274 VVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDR 321
>AL389924-2|CAI41118.1| 725|Homo sapiens FYVE, RhoGEF and PH domain
containing 3 protein.
Length = 725
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 9/168 (5%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRT 183
H+ ++H+E +YV L L + L ++ + I +F + I + H F
Sbjct: 160 HIAQELLHTEETYVKRLHLLDQVFCTRLTDAG---IPPEVIMGIFSNISSIHRFHGQFLL 216
Query: 184 A--LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALAD 241
+ WD + ++G++ A L +Y +++ NF A+ L ++R D
Sbjct: 217 PELKTRITEEWDTNPRLGDILQKL---APFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKD 273
Query: 242 FF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
+++ L+ M++PVQR P++ + L+D LK P DR
Sbjct: 274 VVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDR 321
>AJ437636-1|CAD26885.2| 1606|Homo sapiens P-Rex2 protein protein.
Length = 1606
Score = 54.8 bits (126), Expect = 2e-06
Identities = 49/205 (23%), Positives = 90/205 (43%), Gaps = 9/205 (4%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPD 173
QLR R V++ + +E YV TL+ LV+ + + + + + ++ + ++ LF + D
Sbjct: 20 QLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIED 79
Query: 174 ILQCHLHFRTALADCAQTW-DRDEKIGEVFLSAFSKAVVLDVY-SDFINNFSVAMELAKM 231
IL H F + +C + +++G FL K + D Y S+ + +EL K+
Sbjct: 80 ILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKI 139
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRVXX 291
+ R L + + L G +V P+QR ++ + L++LLK TP H+D
Sbjct: 140 RTIRTFLLNCMLLGGRKNTDVPLE--GYLVTPIQRICKYPLILKELLKRTPRKHSDYAAV 197
Query: 292 XXXXXXXXXXXXXXXXXKRDAERTQ 316
KR E+ +
Sbjct: 198 MEALQAMKAVCSNINEAKRQMEKLE 222
>BX538322-1|CAD98096.1| 1210|Homo sapiens hypothetical protein
protein.
Length = 1210
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
H+ I+ SE +V L+ L D++ + +S P I + Q L++ LP + + +
Sbjct: 874 HIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYY-LPQLYELN 932
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
L + W ++I ++F+ K L +YS +I F + L + K+
Sbjct: 933 RDLLKELEERMLHWTEQQRIADIFVK---KGPYLKMYSTYIKEFDKNIALLDEQCKKNPG 989
Query: 239 LADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
A + ++S L+ ++KPVQR PQ+ + L D LK+
Sbjct: 990 FAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKN 1032
>BC125226-1|AAI25227.1| 639|Homo sapiens FGD6 protein protein.
Length = 639
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
H+ I+ SE +V L+ L D++ + +S P I + Q L++ LP + + +
Sbjct: 83 HIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYY-LPQLYELN 141
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
L + W ++I ++F+ K L +YS +I F + L + K+
Sbjct: 142 RDLLKELEERMLHWTEQQRIADIFVK---KGPYLKMYSTYIKEFDKNIALLDEQCKKNPG 198
Query: 239 LADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
A + ++S L+ ++KPVQR PQ+ + L D LK+
Sbjct: 199 FAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKN 241
>BC125225-1|AAI25226.1| 639|Homo sapiens FGD6 protein protein.
Length = 639
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
H+ I+ SE +V L+ L D++ + +S P I + Q L++ LP + + +
Sbjct: 83 HIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYY-LPQLYELN 141
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
L + W ++I ++F+ K L +YS +I F + L + K+
Sbjct: 142 RDLLKELEERMLHWTEQQRIADIFVK---KGPYLKMYSTYIKEFDKNIALLDEQCKKNPG 198
Query: 239 LADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
A + ++S L+ ++KPVQR PQ+ + L D LK+
Sbjct: 199 FAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKN 241
>AY570973-1|AAS59407.1| 205|Homo sapiens PtdIns(3,4,5)-dependent
rac exchanger-2 protein.
Length = 205
Score = 54.4 bits (125), Expect = 2e-06
Identities = 46/176 (26%), Positives = 85/176 (48%), Gaps = 9/176 (5%)
Query: 119 QLRRRH-VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPD 173
QLR R V++ + +E YV TL+ LV+ + + + + + ++ + ++ LF + D
Sbjct: 11 QLRLRVCVLSELQKTERDYVGTLEFLVSAFLHRMNQCAASKVDKNVTEETVKMLFSNIED 70
Query: 174 ILQCHLHFRTALADCAQTW-DRDEKIGEVFLSAFSKAVVLDVY-SDFINNFSVAMELAKM 231
IL H F + +C + +++G FL K + D Y S+ + +EL K+
Sbjct: 71 ILAVHKEFLKVVEECLHPEPNAQQEVGTCFLHFKDKFRIYDEYCSNHEKAQKLLLELNKI 130
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ R L + + L G +V P+QR ++ + L++LLK TP H+D
Sbjct: 131 RTIRTFLLNCMLLGGRKNTDVPLE--GYLVTPIQRICKYPLILKELLKRTPRKHSD 184
>AK128492-1|BAC87464.1| 1053|Homo sapiens protein ( Homo sapiens
cDNA FLJ46642 fis, clone TRACH3003037, weakly similar
to Rho/Rac guanine nucleotide exchange factor. ).
Length = 1053
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
H+ I+ SE +V L+ L D++ + +S P I + Q L++ LP + + +
Sbjct: 497 HIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYY-LPQLYELN 555
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
L + W ++I ++F+ K L +YS +I F + L + K+
Sbjct: 556 RDLLKELEERMLHWTEQQRIADIFVK---KGPYLKMYSTYIKEFDKNIALLDEQCKKNPG 612
Query: 239 LADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
A + ++S L+ ++KPVQR PQ+ + L D LK+
Sbjct: 613 FAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKN 655
>AK124904-1|BAC85990.1| 1430|Homo sapiens protein ( Homo sapiens cDNA
FLJ42914 fis, clone BRHIP3025161, weakly similar to
Rho/Rac guanine nucleotide exchange factor. ).
Length = 1430
Score = 54.0 bits (124), Expect = 3e-06
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
H+ I+ SE +V L+ L D++ + +S P I + Q L++ LP + + +
Sbjct: 874 HIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYY-LPQLYELN 932
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
L + W ++I ++F+ K L +YS +I F + L + K+
Sbjct: 933 RDLLKELEERMLHWTEHQRIADIFVK---KGPYLKMYSTYIKEFDKNIALLDEQCKKNPG 989
Query: 239 LADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
A + ++S L+ ++KPVQR PQ+ + L D LK+
Sbjct: 990 FAAVVREFEMSPRCANLALKHYLLKPVQRIPQYRLLLTDYLKN 1032
>D63476-1|BAA09763.2| 802|Homo sapiens KIAA0142 protein.
Length = 802
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 253 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 310
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 311 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 365
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 366 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 409
>BC060776-1|AAH60776.1| 803|Homo sapiens ARHGEF7 protein protein.
Length = 803
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 275 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 332
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 333 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 387
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 388 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 431
>BC050521-1|AAH50521.1| 764|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 764
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 215 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 272
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 273 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 327
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 328 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 371
>AL834228-1|CAD38906.1| 812|Homo sapiens hypothetical protein
protein.
Length = 812
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 284 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 341
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 342 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 396
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 397 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 440
>AL390754-5|CAM13628.1| 646|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 646
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 97 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 154
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 155 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 209
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 210 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 253
>AL390754-4|CAI12463.1| 705|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 705
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 97 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 154
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 155 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 209
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 210 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 253
>AL390754-2|CAI12461.1| 625|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 625
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 97 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 154
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 155 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 209
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 210 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 253
>AL139086-4|CAM20788.1| 646|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 646
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 97 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 154
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 155 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 209
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 210 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 253
>AL139086-3|CAI14672.1| 705|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 705
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 97 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 154
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 155 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 209
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 210 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 253
>AL139086-2|CAI14671.1| 625|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 7 protein.
Length = 625
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 97 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 154
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 155 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 209
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 210 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 253
>AB177849-1|BAD66827.1| 680|Homo sapiens KIAA0142 splice variant 2
protein.
Length = 680
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 131 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 188
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 189 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 243
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 244 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 287
>AB177848-1|BAD66826.1| 691|Homo sapiens KIAA0142 splice variant 1
protein.
Length = 691
Score = 53.6 bits (123), Expect = 4e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 253 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 310
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 311 LEECTKLPEAQQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 365
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 366 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 409
>AB037783-1|BAA92600.1| 699|Homo sapiens KIAA1362 protein protein.
Length = 699
Score = 53.6 bits (123), Expect = 4e-06
Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 10/163 (6%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
H+ I+ SE +V L+ L D++ + +S P I + Q L++ LP + + +
Sbjct: 206 HIAKEIMSSEKVFVDVLKLLHIDFRDAVAHASRQLGKPVIEDRILNQILYY-LPQLYELN 264
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
L + W ++I ++F+ K L +YS +I F + L + K+
Sbjct: 265 RDLLKELEERMLHWTEQQRIADIFVK---KGPYLKMYSTYIKEFDKNIALLDEQCKKNPG 321
Query: 239 LADFFKVKQIS-AHDRLSFFGLMVKPVQRFPQFIMFLQDLLKH 280
A + ++S L+ ++KPVQR PQ+ + L D LK+
Sbjct: 322 FAAVVREFEMSPCCANLALKHYLLKPVQRIPQYRLLLTDYLKN 364
>BC033905-1|AAH33905.1| 753|Homo sapiens ARHGEF7 protein protein.
Length = 753
Score = 53.2 bits (122), Expect = 5e-06
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 7/164 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +EN Y LQ +++ Y +PL+ S L+++ I L L +I +
Sbjct: 225 VLQNILETENEYSKELQTVLSTYLRPLQTSEK--LSSANISYLMGNLEEICSFQQMLVQS 282
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C + + +++G FL+ + L Y + N A+ + S+ L +F +
Sbjct: 283 LEECTKLPEAKQRVGGCFLNLMPQMKTL--YLTYCANHPSAVNVLTEHSEE---LGEFME 337
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K S+ L + KP R ++ L++L +H H DR
Sbjct: 338 TKGASSPGILVLTTGLSKPFMRLDKYPTLLKELERHMEDYHTDR 381
>BC057394-1|AAH57394.1| 1562|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 11 protein.
Length = 1562
Score = 52.4 bits (120), Expect = 9e-06
Identities = 35/173 (20%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++ R+ V+ + +E S++ TL+ L + + +++ + ++ ++ LF LP++++ H
Sbjct: 772 EIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEN--LMPREELARLFPNLPELIEIH 829
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAF---SKAVVLDVYSDFINNFSVAMELAKMESKR 235
+ A+ + ++I ++ L+ F ++ + V + F + S+A+EL K + ++
Sbjct: 830 NSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRK 889
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+S F + + RL L++ +QR ++ + L+ ++KHT G ++
Sbjct: 890 ESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSE 942
>BC053655-1|AAH53655.1| 655|Homo sapiens FYVE, RhoGEF and PH domain
containing 2 protein.
Length = 655
Score = 52.4 bits (120), Expect = 9e-06
Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 10/172 (5%)
Query: 123 RHVVAAIIHSENSYVATLQRLVNDYKKPLEES--SPAILNASKIQTLFHRLPDILQCHLH 180
+ +V ++ +E +YVA L L + + L ++ S ++ +F + I Q H
Sbjct: 104 KKIVQELLETEQAYVARLHLLDQVFFQELLKTARSSKAFPEDVVRVIFSNISSIYQFHSQ 163
Query: 181 F-RTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
F L W + +IG+V A L +YS+++ NF A EL + +
Sbjct: 164 FFLPELQRRLDDWTANPRIGDVIQKL---APFLKMYSEYVKNFERAAELLATWTDKSPLF 220
Query: 240 ADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTP---PGHAD 287
+ +++ A L+ M++PVQR P++ + L++ ++ P P AD
Sbjct: 221 QEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQAD 272
>BC040275-1|AAH40275.1| 1181|Homo sapiens RASGRF1 protein protein.
Length = 1181
Score = 52.4 bits (120), Expect = 9e-06
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 13/174 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLE---ESSPAILNASKIQTLFHRLPDILQC 177
+R VV +++ +E YV L LVN++ +PL S + + ++F I+
Sbjct: 240 KRNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFL 299
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAV-VLDVYSDFINNFSVAME-LAKMESKR 235
H F L +W V F + +L++Y +F+ N +++ LA + R
Sbjct: 300 HQIFYQGLKARISSWPT-----LVLADLFDILLPMLNIYQEFVRNHQYSLQILAHCKQNR 354
Query: 236 K-SALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
L ++ K L F + P+ + P++I+ L +LL HTP H +R
Sbjct: 355 DFDKLLKHYEAKPDCEERTLETF--LTYPMFQIPRYILTLHELLAHTPHEHVER 406
>BC023645-1|AAH23645.1| 655|Homo sapiens FYVE, RhoGEF and PH domain
containing 2 protein.
Length = 655
Score = 52.4 bits (120), Expect = 9e-06
Identities = 41/172 (23%), Positives = 78/172 (45%), Gaps = 10/172 (5%)
Query: 123 RHVVAAIIHSENSYVATLQRLVNDYKKPLEES--SPAILNASKIQTLFHRLPDILQCHLH 180
+ +V ++ +E +YVA L L + + L ++ S ++ +F + I Q H
Sbjct: 104 KKIVQELLETEQAYVARLHLLDQVFFQELLKTARSSKAFPEDVVRVIFSNISSIYQFHSQ 163
Query: 181 F-RTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
F L W + +IG+V A L +YS+++ NF A EL + +
Sbjct: 164 FFLPELQRRLDDWTANPRIGDVIQKL---APFLKMYSEYVKNFERAAELLATWTDKSPLF 220
Query: 240 ADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTP---PGHAD 287
+ +++ A L+ M++PVQR P++ + L++ ++ P P AD
Sbjct: 221 QEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQAD 272
>AL356104-3|CAH72940.1| 1522|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 11 protein.
Length = 1522
Score = 52.4 bits (120), Expect = 9e-06
Identities = 35/173 (20%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++ R+ V+ + +E S++ TL+ L + + +++ + ++ ++ LF LP++++ H
Sbjct: 732 EIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEN--LMPREELARLFPNLPELIEIH 789
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAF---SKAVVLDVYSDFINNFSVAMELAKMESKR 235
+ A+ + ++I ++ L+ F ++ + V + F + S+A+EL K + ++
Sbjct: 790 NSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRK 849
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+S F + + RL L++ +QR ++ + L+ ++KHT G ++
Sbjct: 850 ESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSE 902
>AL356104-2|CAH72939.1| 1562|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 11 protein.
Length = 1562
Score = 52.4 bits (120), Expect = 9e-06
Identities = 35/173 (20%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++ R+ V+ + +E S++ TL+ L + + +++ + ++ ++ LF LP++++ H
Sbjct: 772 EIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEN--LMPREELARLFPNLPELIEIH 829
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAF---SKAVVLDVYSDFINNFSVAMELAKMESKR 235
+ A+ + ++I ++ L+ F ++ + V + F + S+A+EL K + ++
Sbjct: 830 NSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRK 889
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+S F + + RL L++ +QR ++ + L+ ++KHT G ++
Sbjct: 890 ESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSE 942
>AL157713-2|CAH70127.1| 1522|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 11 protein.
Length = 1522
Score = 52.4 bits (120), Expect = 9e-06
Identities = 35/173 (20%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++ R+ V+ + +E S++ TL+ L + + +++ + ++ ++ LF LP++++ H
Sbjct: 732 EIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEN--LMPREELARLFPNLPELIEIH 789
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAF---SKAVVLDVYSDFINNFSVAMELAKMESKR 235
+ A+ + ++I ++ L+ F ++ + V + F + S+A+EL K + ++
Sbjct: 790 NSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRK 849
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+S F + + RL L++ +QR ++ + L+ ++KHT G ++
Sbjct: 850 ESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSE 902
>AL157713-1|CAH70128.1| 1562|Homo sapiens Rho guanine nucleotide
exchange factor (GEF) 11 protein.
Length = 1562
Score = 52.4 bits (120), Expect = 9e-06
Identities = 35/173 (20%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++ R+ V+ + +E S++ TL+ L + + +++ + ++ ++ LF LP++++ H
Sbjct: 772 EIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEN--LMPREELARLFPNLPELIEIH 829
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAF---SKAVVLDVYSDFINNFSVAMELAKMESKR 235
+ A+ + ++I ++ L+ F ++ + V + F + S+A+EL K + ++
Sbjct: 830 NSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRK 889
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+S F + + RL L++ +QR ++ + L+ ++KHT G ++
Sbjct: 890 ESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSE 942
>AB002378-1|BAA20834.2| 1539|Homo sapiens KIAA0380 protein protein.
Length = 1539
Score = 52.4 bits (120), Expect = 9e-06
Identities = 35/173 (20%), Positives = 90/173 (52%), Gaps = 6/173 (3%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++ R+ V+ + +E S++ TL+ L + + +++ + ++ ++ LF LP++++ H
Sbjct: 749 EIDRQEVINELFVTEASHLRTLRVLDLIFYQRMKKEN--LMPREELARLFPNLPELIEIH 806
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAF---SKAVVLDVYSDFINNFSVAMELAKMESKR 235
+ A+ + ++I ++ L+ F ++ + V + F + S+A+EL K + ++
Sbjct: 807 NSWCEAMKKLREEGPIIKEISDLMLARFDGPAREELQQVAAQFCSYQSIALELIKTKQRK 866
Query: 236 KSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+S F + + RL L++ +QR ++ + L+ ++KHT G ++
Sbjct: 867 ESRFQLFMQEAESHPQCRRLQLRDLIISEMQRLTKYPLLLESIIKHTEGGTSE 919
>AY533677-1|AAS57923.1| 257|Homo sapiens BCR protein.
Length = 257
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/83 (27%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 19 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 78
Query: 180 HFRTALADCAQTWDRDEKIGEVF 202
F L Q W +++G++F
Sbjct: 79 EFYDGLFPRVQQWSHQQRVGDLF 101
Score = 35.5 bits (78), Expect = 1.1
Identities = 15/29 (51%), Positives = 18/29 (62%)
Query: 259 LMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
L+ KPV R + + L DLLKHTP H D
Sbjct: 126 LLYKPVDRVTRSTLVLHDLLKHTPASHPD 154
>AJ298916-1|CAC82654.1| 251|Homo sapiens BCR/FGFR1 chimaeric fusion
protein protein.
Length = 251
Score = 51.6 bits (118), Expect = 2e-05
Identities = 23/83 (27%), Positives = 48/83 (57%), Gaps = 2/83 (2%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 128 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHK 187
Query: 180 HFRTALADCAQTWDRDEKIGEVF 202
F L Q W +++G++F
Sbjct: 188 EFYDGLFPRVQQWSHQQRVGDLF 210
>AY536245-1|AAS46907.1| 144|Homo sapiens breakpoint cluster region
protein protein.
Length = 144
Score = 51.2 bits (117), Expect = 2e-05
Identities = 24/84 (28%), Positives = 48/84 (57%), Gaps = 2/84 (2%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCHL 179
R+ V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T F ++P++ + H
Sbjct: 19 RKWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETNFFKVPELYEIHK 78
Query: 180 HFRTALADCAQTWDRDEKIGEVFL 203
F L Q W +++G++FL
Sbjct: 79 EFYDGLFPHVQQWSHQQRVGDLFL 102
>L26584-1|AAA58417.1| 1275|Homo sapiens CDC25 protein.
Length = 1275
Score = 50.8 bits (116), Expect = 3e-05
Identities = 42/173 (24%), Positives = 76/173 (43%), Gaps = 11/173 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLE---ESSPAILNASKIQTLFHRLPDILQC 177
+R VV +++ +E YV L LVN++ +PL S + + ++F I+
Sbjct: 240 KRNQVVFSMLEAEAEYVQQLHILVNNFLRPLRMAASSKKPPITHDDVSSIFLNSETIMFL 299
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRK 236
H F L +W + L +L++Y +F+ N +++ LA + R
Sbjct: 300 HQIFYQGLKARISSWPT--LVLADLLDILLP--MLNIYQEFVRNHQYSLQILAHCKQNRD 355
Query: 237 -SALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
L ++ K L F + P+ + P++I+ L D+L HTP H +R
Sbjct: 356 FDKLLKHYEAKPDCEERTLETF--LTYPMFQIPRYILTLHDVLAHTPHEHVER 406
>BC013361-1|AAH13361.2| 790|Homo sapiens VAV1 protein protein.
Length = 790
Score = 50.8 bits (116), Expect = 3e-05
Identities = 36/153 (23%), Positives = 70/153 (45%), Gaps = 7/153 (4%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
I +E Y TL + + KPL+ L I+ +F + D+L+ H HF + +
Sbjct: 147 IQQTEEKYTDTLGSIQQHFLKPLQR----FLKPQDIEIIFINIEDLLRVHTHFLKEMKEA 202
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFKVKQI 248
T + +VF+ + +V Y + S + L ++ + R+ + Q
Sbjct: 203 LGT-PGAANLYQVFIKYKERFLVYGRYCSQVE--SASKHLDRVAAAREDVQMKLEECSQR 259
Query: 249 SAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + R + L++ P+QR ++ + LQ+L+KHT
Sbjct: 260 ANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHT 292
>AF030227-1|AAC25011.1| 845|Homo sapiens vav protein protein.
Length = 845
Score = 50.8 bits (116), Expect = 3e-05
Identities = 36/153 (23%), Positives = 70/153 (45%), Gaps = 7/153 (4%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
I +E Y TL + + KPL+ L I+ +F + D+L+ H HF + +
Sbjct: 202 IQQTEEKYTDTLGSIQQHFLKPLQR----FLKPQDIEIIFINIEDLLRVHTHFLKEMKEA 257
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFKVKQI 248
T + +VF+ + +V Y + S + L ++ + R+ + Q
Sbjct: 258 LGT-PGAANLYQVFIKYKERFLVYGRYCSQVE--SASKHLDRVAAAREDVQMKLEECSQR 314
Query: 249 SAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + R + L++ P+QR ++ + LQ+L+KHT
Sbjct: 315 ANNGRFTLRDLLMVPMQRVLKYHLLLQELVKHT 347
>BC045552-1|AAH45552.1| 471|Homo sapiens FGD4 protein protein.
Length = 471
Score = 50.0 bits (114), Expect = 5e-05
Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 11/129 (8%)
Query: 164 IQTLFHRLPDILQCHLHFRTA-LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNF 222
+ +F + I H F L Q W+ +IG++ A L +Y +++ F
Sbjct: 2 VNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKL---APFLKMYGEYVKGF 58
Query: 223 SVAMELAKMESKR----KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLL 278
AMEL K ++R KS + + K K + L+ M++PVQR P++ M L+D L
Sbjct: 59 DNAMELVKNMTERIPQFKSVVEEIQKQKICGS---LTLQHHMLEPVQRIPRYEMLLKDYL 115
Query: 279 KHTPPGHAD 287
+ PP D
Sbjct: 116 RKLPPDSLD 124
>AF180681-1|AAF36817.1| 1544|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 1544
Score = 50.0 bits (114), Expect = 5e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 8/169 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
+++R+ V+ + ++E ++V TL+ L + + + S IL+ S+++ +F L DILQ H
Sbjct: 785 EIKRQEVINELFYTERAHVRTLKVLDQVFYQRV--SREGILSPSELRKIFSNLEDILQLH 842
Query: 179 LHFRTALADCAQTWDRD--EKIGEVFLSAFS---KAVVLDVYSDFINNFSVAMELAKMES 233
+ + + + ++IGE L+ FS + + + F +N A+E+ K
Sbjct: 843 IGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQ 902
Query: 234 KRKSALADFFK-VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K+ S F + + RL ++ +QR ++ + L ++ K+T
Sbjct: 903 KKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYT 951
>AB002380-1|BAA20836.2| 1443|Homo sapiens KIAA0382 protein protein.
Length = 1443
Score = 50.0 bits (114), Expect = 5e-05
Identities = 39/169 (23%), Positives = 83/169 (49%), Gaps = 8/169 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
+++R+ V+ + ++E ++V TL+ L + + + S IL+ S+++ +F L DILQ H
Sbjct: 684 EIKRQEVINELFYTERAHVRTLKVLDQVFYQRV--SREGILSPSELRKIFSNLEDILQLH 741
Query: 179 LHFRTALADCAQTWDRD--EKIGEVFLSAFS---KAVVLDVYSDFINNFSVAMELAKMES 233
+ + + + ++IGE L+ FS + + + F +N A+E+ K
Sbjct: 742 IGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQ 801
Query: 234 KRKSALADFFK-VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K+ S F + + RL ++ +QR ++ + L ++ K+T
Sbjct: 802 KKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYT 850
>BC109291-1|AAI09292.1| 652|Homo sapiens spermatogenesis associated
13 protein.
Length = 652
Score = 49.2 bits (112), Expect = 9e-05
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 9/172 (5%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q R +V+ I+ +E Y+ L+ + Y + + + + +++ T+F + DI +
Sbjct: 238 QQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHT-GMFTVAQLATIFGNIEDIYKFQ 296
Query: 179 LHFRTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNFSVA-MELAKMESKRK 236
F L D + ++++E + E+ +YS++ NN A +ELA + + K
Sbjct: 297 RKF---LKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGK 353
Query: 237 SALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H D
Sbjct: 354 --YRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGD 403
>BC109290-1|AAI09291.1| 652|Homo sapiens spermatogenesis associated
13 protein.
Length = 652
Score = 49.2 bits (112), Expect = 9e-05
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 9/172 (5%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q R +V+ I+ +E Y+ L+ + Y + + + + +++ T+F + DI +
Sbjct: 238 QQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHT-GMFTVAQLATIFGNIEDIYKFQ 296
Query: 179 LHFRTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNFSVA-MELAKMESKRK 236
F L D + ++++E + E+ +YS++ NN A +ELA + + K
Sbjct: 297 RKF---LKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGK 353
Query: 237 SALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H D
Sbjct: 354 --YRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGD 403
>BC020208-1|AAH20208.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 600 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 657
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 658 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 709
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 710 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 753
>BC011853-1|AAH11853.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 600 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 657
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 658 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 709
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 710 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 753
>AL596093-7|CAI39525.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 600 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 657
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 658 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 709
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 710 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 753
>AL596093-6|CAI94928.1| 1067|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1067
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 606 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 663
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 664 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 715
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 716 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 759
>AL596093-4|CAI39524.2| 1096|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1096
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 635 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 692
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 693 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 744
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 745 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 788
>AL596093-3|CAI39523.1| 1137|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1137
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 632 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 689
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 690 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 741
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 742 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 785
>AL359736-2|CAH72290.2| 574|Homo sapiens spermatogenesis associated
13 protein.
Length = 574
Score = 49.2 bits (112), Expect = 9e-05
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 9/172 (5%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q R +V+ I+ +E Y+ L+ + Y + + + + +++ T+F + DI +
Sbjct: 160 QQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHT-GMFTVAQLATIFGNIEDIYKFQ 218
Query: 179 LHFRTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNFSVA-MELAKMESKRK 236
F L D + ++++E + E+ +YS++ NN A +ELA + + K
Sbjct: 219 RKF---LKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGK 275
Query: 237 SALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H D
Sbjct: 276 --YRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGD 325
>AL359736-1|CAH72289.1| 652|Homo sapiens spermatogenesis associated
13 protein.
Length = 652
Score = 49.2 bits (112), Expect = 9e-05
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 9/172 (5%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q R +V+ I+ +E Y+ L+ + Y + + + + +++ T+F + DI +
Sbjct: 238 QQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHT-GMFTVAQLATIFGNIEDIYKFQ 296
Query: 179 LHFRTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNFSVA-MELAKMESKRK 236
F L D + ++++E + E+ +YS++ NN A +ELA + + K
Sbjct: 297 RKF---LKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGK 353
Query: 237 SALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H D
Sbjct: 354 --YRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGD 403
>AL356740-10|CAH70245.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 600 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 657
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 658 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 709
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 710 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 753
>AL356740-8|CAI94923.1| 1067|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1067
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 606 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 663
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 664 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 715
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 716 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 759
>AL356740-6|CAH70244.2| 1096|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1096
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 635 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 692
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 693 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 744
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 745 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 788
>AL356740-4|CAH70243.1| 1137|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1137
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 632 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 689
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 690 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 741
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 742 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 785
>AL162454-4|CAI39871.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 600 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 657
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 658 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 709
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 710 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 753
>AL162454-3|CAI95103.1| 1067|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1067
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 606 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 663
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 664 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 715
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 716 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 759
>AL162454-2|CAI39870.2| 1096|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1096
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 635 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 692
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 693 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 744
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 745 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 788
>AL162454-1|CAI39869.1| 1137|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1137
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 632 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 689
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 690 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 741
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 742 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 785
>AL137002-20|CAI41392.1| 984|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 984
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 600 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 657
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 658 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 709
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 710 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 753
>AL137002-18|CAI95400.1| 1067|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1067
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 606 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 663
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 664 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 715
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 716 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 759
>AL137002-17|CAI41390.2| 1096|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1096
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 635 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 692
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 693 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 744
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 745 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 788
>AL137002-11|CAI41383.1| 1137|Homo sapiens MCF.2 cell line derived
transforming sequence-like protein.
Length = 1137
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 632 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 689
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 690 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 741
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 742 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 785
>AK160371-1|BAD18714.1| 527|Homo sapiens FLJ00298 protein protein.
Length = 527
Score = 49.2 bits (112), Expect = 9e-05
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 9/172 (5%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q R +V+ I+ +E Y+ L+ + Y + + + + +++ T+F + DI +
Sbjct: 113 QQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHT-GMFTVAQLATIFGNIEDIYKFQ 171
Query: 179 LHFRTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNFSVA-MELAKMESKRK 236
F L D + ++++E + E+ +YS++ NN A +ELA + + K
Sbjct: 172 RKF---LKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGK 228
Query: 237 SALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H D
Sbjct: 229 --YRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGD 278
>AK055770-1|BAB71009.1| 652|Homo sapiens factor. protein.
Length = 652
Score = 49.2 bits (112), Expect = 9e-05
Identities = 39/172 (22%), Positives = 82/172 (47%), Gaps = 9/172 (5%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
Q R +V+ I+ +E Y+ L+ + Y + + + + +++ T+F + DI +
Sbjct: 238 QQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHT-GMFTVAQLATIFGNIEDIYKFQ 296
Query: 179 LHFRTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINNFSVA-MELAKMESKRK 236
F L D + ++++E + E+ +YS++ NN A +ELA + + K
Sbjct: 297 RKF---LKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGK 353
Query: 237 SALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H D
Sbjct: 354 --YRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGD 403
>AF118886-1|AAD20348.1| 753|Homo sapiens VAV-3 protein beta isoform
protein.
Length = 753
Score = 49.2 bits (112), Expect = 9e-05
Identities = 34/157 (21%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 103 LAEIKQTEEKYTETLESIEKHFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 158
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRKSALADFFK 244
D D+ + +VF++ + V+ Y + + +++ ++K + K L + K
Sbjct: 159 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSK 217
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 218 RAN---NGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 251
>AB116075-1|BAD08352.1| 904|Homo sapiens Ost-I protein.
Length = 904
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 443 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 500
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 501 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 552
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 553 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 596
>AB116074-1|BAD08351.1| 1067|Homo sapiens Ost-II protein.
Length = 1067
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 606 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 663
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 664 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 715
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 716 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 759
>AB002360-1|BAA20817.1| 1108|Homo sapiens KIAA0362 protein.
Length = 1108
Score = 49.2 bits (112), Expect = 9e-05
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 14/164 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNAS----KIQTLFHRLPDILQC 177
RRHV++ ++ +E +YV L ++ Y ++ A L ++ K LF + +I
Sbjct: 647 RRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIY-- 704
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
H H R L + D E +G FL +Y + N + L R+
Sbjct: 705 HFHNRIFLRELENYTDCPELVGRCFLERMED---FQIYEKYCQNKPRSESLW-----RQC 756
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q +LS ++KPVQR ++ + L+++LK++
Sbjct: 757 SDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYS 800
>U42390-1|AAC34245.1| 2861|Homo sapiens Trio protein.
Length = 2861
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 120 LRRRH-VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
L+RRH V+ ++ +E YV L +V Y ++E K + +F + I H
Sbjct: 1908 LKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWH 1967
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F L + + + EK+G +F+ + L +Y + N K E
Sbjct: 1968 RDF--FLGELEKCLEDPEKLGSLFVKHERR---LHMYIAYCQN------KPKSEHIVSEY 2016
Query: 239 LADFFK-VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ FF+ +KQ H RL L++KPVQR ++ + L+D LK++ D
Sbjct: 2017 IDTFFEDLKQRLGH-RLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLD 2065
Score = 34.3 bits (75), Expect = 2.6
Identities = 37/162 (22%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDY----KKPLEESSPAILNASKIQTLFHRLPDILQ 176
R+ ++A +I +E +YV L+ ++ Y +EE P I+N I +F + +I +
Sbjct: 1233 RKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELI--IFGNMQEIYE 1290
Query: 177 CHLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRK 236
H + L + + E +G F++ K +Y + N + +L +
Sbjct: 1291 FHNNI--FLKELEKYEQLPEDVGHCFVTWADK---FQMYVTYCKNKPDSTQLIL-----E 1340
Query: 237 SALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLL 278
A + F +++Q S ++KPVQR ++ + L++LL
Sbjct: 1341 HAGSYFDEIQQRHGLAN-SISSYLIKPVQRITKYQLLLKELL 1381
>AF091395-1|AAC43042.1| 3038|Homo sapiens Trio isoform protein.
Length = 3038
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 120 LRRRH-VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
L+RRH V+ ++ +E YV L +V Y ++E K + +F + I H
Sbjct: 1908 LKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWH 1967
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F L + + + EK+G +F+ + L +Y + N K E
Sbjct: 1968 RDF--FLGELEKCLEDPEKLGSLFVKHERR---LHMYIAYCQN------KPKSEHIVSEY 2016
Query: 239 LADFFK-VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ FF+ +KQ H RL L++KPVQR ++ + L+D LK++ D
Sbjct: 2017 IDTFFEDLKQRLGH-RLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLD 2065
Score = 34.3 bits (75), Expect = 2.6
Identities = 37/162 (22%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDY----KKPLEESSPAILNASKIQTLFHRLPDILQ 176
R+ ++A +I +E +YV L+ ++ Y +EE P I+N I +F + +I +
Sbjct: 1233 RKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELI--IFGNMQEIYE 1290
Query: 177 CHLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRK 236
H + L + + E +G F++ K +Y + N + +L +
Sbjct: 1291 FHNNI--FLKELEKYEQLPEDVGHCFVTWADK---FQMYVTYCKNKPDSTQLIL-----E 1340
Query: 237 SALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLL 278
A + F +++Q S ++KPVQR ++ + L++LL
Sbjct: 1341 HAGSYFDEIQQRHGLAN-SISSYLIKPVQRITKYQLLLKELL 1381
>AF067817-1|AAC79695.1| 847|Homo sapiens VAV-3 protein protein.
Length = 847
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/156 (20%), Positives = 73/156 (46%), Gaps = 7/156 (4%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 197 LAEIKQTEEKYTETLESIEKYFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 252
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFKV 245
D D+ + +VF++ + V+ Y + S L + ++ +
Sbjct: 253 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVE--SAISSLDYISKSKEDVKLKLEEC 309
Query: 246 KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 310 SKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 345
>AB209754-1|BAD92991.1| 2202|Homo sapiens triple functional domain
(PTPRF interacting) variant protein.
Length = 2202
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 120 LRRRH-VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
L+RRH V+ ++ +E YV L +V Y ++E K + +F + I H
Sbjct: 1606 LKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWH 1665
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F L + + + EK+G +F+ + L +Y + N K E
Sbjct: 1666 RDF--FLGELEKCLEDPEKLGSLFVKHERR---LHMYIAYCQN------KPKSEHIVSEY 1714
Query: 239 LADFFK-VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ FF+ +KQ H RL L++KPVQR ++ + L+D LK++ D
Sbjct: 1715 IDTFFEDLKQRLGH-RLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLD 1763
Score = 34.3 bits (75), Expect = 2.6
Identities = 37/162 (22%), Positives = 74/162 (45%), Gaps = 17/162 (10%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDY----KKPLEESSPAILNASKIQTLFHRLPDILQ 176
R+ ++A +I +E +YV L+ ++ Y +EE P I+N I +F + +I +
Sbjct: 931 RKEFIMAELIQTEKAYVRDLRECMDTYLWEMTSGVEEIPPGIVNKELI--IFGNMQEIYE 988
Query: 177 CHLHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRK 236
H + L + + E +G F++ K +Y + N + +L +
Sbjct: 989 FHNNI--FLKELEKYEQLPEDVGHCFVTWADK---FQMYVTYCKNKPDSTQLIL-----E 1038
Query: 237 SALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLL 278
A + F +++Q S ++KPVQR ++ + L++LL
Sbjct: 1039 HAGSYFDEIQQRHGLAN-SISSYLIKPVQRITKYQLLLKELL 1079
>AB115332-1|BAC79392.1| 255|Homo sapiens transforming gene product
TGAT protein.
Length = 255
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/170 (26%), Positives = 76/170 (44%), Gaps = 14/170 (8%)
Query: 120 LRRRH-VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
L+RRH V+ ++ +E YV L +V Y ++E K + +F + I H
Sbjct: 47 LKRRHYVLQELVETERDYVRDLGYVVEGYMALMKEDGVPDDMKGKDKIVFGNIHQIYDWH 106
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
F L + + + EK+G +F+ + L +Y + N K E
Sbjct: 107 RDF--FLGELEKCLEDPEKLGSLFVKHERR---LHMYIAYCQN------KPKSEHIVSEY 155
Query: 239 LADFFK-VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ FF+ +KQ H RL L++KPVQR ++ + L+D LK++ D
Sbjct: 156 IDTFFEDLKQRLGH-RLQLTDLLIKPVQRIMKYQLLLKDFLKYSKKASLD 204
>BC126112-1|AAI26113.1| 1237|Homo sapiens Ras protein-specific
guanine nucleotide-releasing factor 2 protein.
Length = 1237
Score = 48.4 bits (110), Expect = 2e-04
Identities = 40/174 (22%), Positives = 75/174 (43%), Gaps = 13/174 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLE---ESSPAILNASKIQTLFHRLPDILQC 177
+R +V ++ +E+ YV L LVN + +PL S ++ + ++F I+
Sbjct: 243 KRNQIVFTMVEAESEYVHQLYILVNGFLRPLRMAASSKKPPISHDDVSSIFLNSETIMFL 302
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAV-VLDVYSDFINNFSVAME-LAKMESKR 235
H F L W + F + +L++Y +F+ N +++ LA + R
Sbjct: 303 HEIFHQGLKARIANWPT-----LILADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNR 357
Query: 236 K-SALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
L ++ L F + P+ + P++I+ L +LL HTP H +R
Sbjct: 358 DFDKLLKQYEANPACEGRMLETF--LTYPMFQIPRYIITLHELLAHTPHEHVER 409
>AY367054-1|AAQ72372.1| 280|Homo sapiens actin-filament binding
protein frabin protein.
Length = 280
Score = 48.4 bits (110), Expect = 2e-04
Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 11/129 (8%)
Query: 164 IQTLFHRLPDILQCHLHFRTA-LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNF 222
+ +F + I H F L Q W+ +IG++ A L +Y ++ F
Sbjct: 2 VNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKL---APFLKMYGEYAKGF 58
Query: 223 SVAMELAKMESKR----KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLL 278
AMEL K ++R KS + + K K + L+ M++PVQR P++ M L+D L
Sbjct: 59 DNAMELVKNMTERIPQFKSVVEEIQKQKICGS---LTLQHHMLEPVQRIPRYEMLLKDYL 115
Query: 279 KHTPPGHAD 287
+ PP D
Sbjct: 116 RKLPPDSLD 124
>AL591042-2|CAI14458.1| 753|Homo sapiens vav 3 oncogene protein.
Length = 753
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/157 (21%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 103 LAEIKQTEEKYTETLESIEKYFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 158
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRKSALADFFK 244
D D+ + +VF++ + V+ Y + + +++ ++K + K L + K
Sbjct: 159 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSK 217
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 218 RAN---NGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 251
>AL591042-1|CAI14457.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/157 (21%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 197 LAEIKQTEEKYTETLESIEKYFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 252
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRKSALADFFK 244
D D+ + +VF++ + V+ Y + + +++ ++K + K L + K
Sbjct: 253 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSK 311
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 312 RAN---NGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 345
>AL513206-2|CAH73196.1| 753|Homo sapiens vav 3 oncogene protein.
Length = 753
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/157 (21%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 103 LAEIKQTEEKYTETLESIEKYFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 158
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRKSALADFFK 244
D D+ + +VF++ + V+ Y + + +++ ++K + K L + K
Sbjct: 159 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSK 217
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 218 RAN---NGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 251
>AL513206-1|CAH73195.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/157 (21%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 197 LAEIKQTEEKYTETLESIEKYFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 252
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRKSALADFFK 244
D D+ + +VF++ + V+ Y + + +++ ++K + K L + K
Sbjct: 253 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSK 311
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 312 RAN---NGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 345
>AL391235-1|CAH72458.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/157 (21%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 197 LAEIKQTEEKYTETLESIEKYFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 252
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRKSALADFFK 244
D D+ + +VF++ + V+ Y + + +++ ++K + K L + K
Sbjct: 253 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSK 311
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 312 RAN---NGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 345
>AL353892-1|CAI21786.1| 847|Homo sapiens vav 3 oncogene protein.
Length = 847
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/157 (21%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 197 LAEIKQTEEKYTETLESIEKYFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 252
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRKSALADFFK 244
D D+ + +VF++ + V+ Y + + +++ ++K + K L + K
Sbjct: 253 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSK 311
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 312 RAN---NGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 345
>AF181250-1|AAD55268.1| 1237|Homo sapiens Ras guanine nucleotide
exchange factor 2 protein.
Length = 1237
Score = 48.4 bits (110), Expect = 2e-04
Identities = 40/174 (22%), Positives = 75/174 (43%), Gaps = 13/174 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLE---ESSPAILNASKIQTLFHRLPDILQC 177
+R +V ++ +E+ YV L LVN + +PL S ++ + ++F I+
Sbjct: 243 KRNQIVFTMVEAESEYVHQLYILVNGFLRPLRMAASSKKPPISHDDVSSIFLNSETIMFL 302
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAV-VLDVYSDFINNFSVAME-LAKMESKR 235
H F L W + F + +L++Y +F+ N +++ LA + R
Sbjct: 303 HEIFHQGLKARIANWPT-----LILADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNR 357
Query: 236 K-SALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
L ++ L F + P+ + P++I+ L +LL HTP H +R
Sbjct: 358 DFDKLLKQYEANPACEGRMLETF--LTYPMFQIPRYIITLHELLAHTPHEHVER 409
>AF118887-1|AAD20349.1| 847|Homo sapiens VAV-3 protein protein.
Length = 847
Score = 48.4 bits (110), Expect = 2e-04
Identities = 34/157 (21%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTAL 185
+A I +E Y TL+ + + PL+ L A++ ++F +P++++ H + +
Sbjct: 197 LAEIKQTEEKYTETLESIEKYFMAPLKR----FLTAAEFDSVFINIPELVKLHRNLMQEI 252
Query: 186 ADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME-LAKMESKRKSALADFFK 244
D D+ + +VF++ + V+ Y + + +++ ++K + K L + K
Sbjct: 253 HDSIVN-KNDQNLYQVFINYKERLVIYGQYCSGVESAISSLDYISKTKEDVKLKLEECSK 311
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ + + L+V P+QR ++ + LQ+L+KHT
Sbjct: 312 RAN---NGKFTLRDLLVVPMQRVLKYHLLLQELVKHT 345
>AF023130-1|AAB80953.1| 1237|Homo sapiens Ras-GRF2 protein.
Length = 1237
Score = 48.4 bits (110), Expect = 2e-04
Identities = 40/174 (22%), Positives = 75/174 (43%), Gaps = 13/174 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLE---ESSPAILNASKIQTLFHRLPDILQC 177
+R +V ++ +E+ YV L LVN + +PL S ++ + ++F I+
Sbjct: 243 KRNQIVFTMVEAESEYVHQLYILVNGFLRPLRMAASSKKPPISHDDVSSIFLNSETIMFL 302
Query: 178 HLHFRTALADCAQTWDRDEKIGEVFLSAFSKAV-VLDVYSDFINNFSVAME-LAKMESKR 235
H F L W + F + +L++Y +F+ N +++ LA + R
Sbjct: 303 HEIFHQGLKARIANWPT-----LILADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNR 357
Query: 236 K-SALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
L ++ L F + P+ + P++I+ L +LL HTP H +R
Sbjct: 358 DFDKLLKQYEANPACEGRMLETF--LTYPMFQIPRYIITLHELLAHTPHEHVER 409
>BC117406-1|AAI17407.1| 516|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 516
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 104 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 162
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 163 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 217
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 218 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 266
>AL451106-3|CAI39552.1| 478|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 478
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 102 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 160
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 161 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 215
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 216 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 264
>AL451106-1|CAI39550.1| 516|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 516
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 104 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 162
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 163 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 217
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 218 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 266
>AL391277-3|CAI40403.1| 478|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 478
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 102 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 160
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 161 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 215
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 216 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 264
>AL391277-2|CAI40402.1| 495|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 495
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 83 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 141
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 142 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 196
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 197 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 245
>AL391277-1|CAI40401.1| 516|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 516
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 104 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 162
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 163 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 217
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 218 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 266
>AL355142-3|CAI41197.1| 478|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 478
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 102 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 160
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 161 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 215
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 216 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 264
>AL355142-2|CAI41196.1| 495|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 495
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 83 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 141
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 142 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 196
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 197 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 245
>AL355142-1|CAI41195.1| 516|Homo sapiens Cdc42 guanine nucleotide
exchange factor (GEF) 9 protein.
Length = 516
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 104 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 162
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 163 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 217
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 218 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 266
>AB007884-1|BAA24854.2| 567|Homo sapiens KIAA0424 protein.
Length = 567
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/169 (21%), Positives = 81/169 (47%), Gaps = 9/169 (5%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R +V+ I+ +E Y+ L+ + Y K + + + +++ +F + DI + + F
Sbjct: 155 RANVINEIMSTERHYIKHLKDICEGYLKQCRKRRD-MFSDEQLKVIFGNIEDIYRFQMGF 213
Query: 182 RTALADCAQTWDRDEK-IGEVFLSAFSKAVVLDVYSDFINN-FSVAMELAKMESKRKSAL 239
+ D + ++ D+ + E+ +YS++ NN MEL+K+ + S
Sbjct: 214 ---VRDLEKQYNNDDPHLSEIGPCFLEHQDGFWIYSEYCNNHLDACMELSKL--MKDSRY 268
Query: 240 ADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
FF+ + + ++ G ++ PVQ+ ++ + L +LLK+T H+D
Sbjct: 269 QHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTAQDHSD 317
>AL160264-1|CAI20471.1| 697|Homo sapiens FYVE, RhoGEF and PH domain
containing 2 protein.
Length = 697
Score = 47.2 bits (107), Expect = 4e-04
Identities = 42/182 (23%), Positives = 81/182 (44%), Gaps = 20/182 (10%)
Query: 123 RHVVAAIIHSENSYVATLQRL---VNDYKKPLEESSPAILNASK---------IQTLFHR 170
+ +V ++ +E +YVA L L ++D L+ +L ++ ++ +F
Sbjct: 104 KKIVQELLETEQAYVARLHLLDQAMSDLSWRLQVFFQELLKTARSSKAFPEDVVRVIFSN 163
Query: 171 LPDILQCHLHF-RTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELA 229
+ I Q H F L W + +IG+V A L +YS+++ NF A EL
Sbjct: 164 ISSIYQFHSQFFLPELQRRLDDWTANPRIGDVIQKL---APFLKMYSEYVKNFERAAELL 220
Query: 230 KMESKRKSALADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTP---PGH 285
+ + + +++ A L+ M++PVQR P++ + L++ ++ P P
Sbjct: 221 ATWTDKSPLFQEVLTRIQSSEASGSLTLQHHMLEPVQRIPRYELLLKEYIQKLPAQAPDQ 280
Query: 286 AD 287
AD
Sbjct: 281 AD 282
>U02081-1|AAB08847.1| 460|Homo sapiens guanine nucleotide
regulatory protein protein.
Length = 460
Score = 46.8 bits (106), Expect = 5e-04
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 7/170 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++RR+ + + E + L+ Y P+ + S I++ ++ +F L + H
Sbjct: 30 EIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLS--IMSEEELTHIFGDLDSYIPLH 87
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
T + + + E+IG + +S + L+ Y + +N A L + K+
Sbjct: 88 EDLLTRIGEATKPDGTVEQIGHILVSWLPR---LNAYRGYCSNQLAAKALLD-QKKQDPR 143
Query: 239 LADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ DF + S R L + + P R ++ + L+++LKHTP H D
Sbjct: 144 VQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPD 193
>BC053553-1|AAH53553.1| 596|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 596
Score = 46.8 bits (106), Expect = 5e-04
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 7/170 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++RR+ + + E + L+ Y P+ + S I++ ++ +F L + H
Sbjct: 172 EIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLS--IMSEEELTHIFGDLDSYIPLH 229
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
T + + + E+IG + +S + L+ Y + +N A L + K+
Sbjct: 230 EDLLTRIGEATKPDGTVEQIGHILVSWLPR---LNAYRGYCSNQLAAKALLD-QKKQDPR 285
Query: 239 LADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ DF + S R L + + P R ++ + L+++LKHTP H D
Sbjct: 286 VQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPD 335
>BC010285-1|AAH10285.1| 542|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 542
Score = 46.8 bits (106), Expect = 5e-04
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 7/170 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++RR+ + + E + L+ Y P+ + S I++ ++ +F L + H
Sbjct: 118 EIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLS--IMSEEELTHIFGDLDSYIPLH 175
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
T + + + E+IG + +S + L+ Y + +N A L + K+
Sbjct: 176 EDLLTRIGEATKPDGTVEQIGHILVSWLPR---LNAYRGYCSNQLAAKALLD-QKKQDPR 231
Query: 239 LADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ DF + S R L + + P R ++ + L+++LKHTP H D
Sbjct: 232 VQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPD 281
>AL732437-5|CAI11033.1| 596|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 596
Score = 46.8 bits (106), Expect = 5e-04
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 7/170 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++RR+ + + E + L+ Y P+ + S I++ ++ +F L + H
Sbjct: 172 EIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLS--IMSEEELTHIFGDLDSYIPLH 229
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
T + + + E+IG + +S + L+ Y + +N A L + K+
Sbjct: 230 EDLLTRIGEATKPDGTVEQIGHILVSWLPR---LNAYRGYCSNQLAAKALLD-QKKQDPR 285
Query: 239 LADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ DF + S R L + + P R ++ + L+++LKHTP H D
Sbjct: 286 VQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPD 335
>AL732437-3|CAI11031.1| 542|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 542
Score = 46.8 bits (106), Expect = 5e-04
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 7/170 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++RR+ + + E + L+ Y P+ + S I++ ++ +F L + H
Sbjct: 118 EIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLS--IMSEEELTHIFGDLDSYIPLH 175
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
T + + + E+IG + +S + L+ Y + +N A L + K+
Sbjct: 176 EDLLTRIGEATKPDGTVEQIGHILVSWLPR---LNAYRGYCSNQLAAKALLD-QKKQDPR 231
Query: 239 LADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ DF + S R L + + P R ++ + L+++LKHTP H D
Sbjct: 232 VQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPD 281
>AJ010046-1|CAA08974.1| 548|Homo sapiens guanine
nucleotide-exchange factor protein.
Length = 548
Score = 46.8 bits (106), Expect = 5e-04
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 7/170 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++RR+ + + E + L+ Y P+ + S I++ ++ +F L + H
Sbjct: 118 EIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLS--IMSEEELTHIFGDLDSYIPLH 175
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
T + + + E+IG + +S + L+ Y + +N A L + K+
Sbjct: 176 EDLLTRIGEATKPDGTVEQIGHILVSWLPR---LNAYRGYCSNQLAAKALLD-QKKQDPR 231
Query: 239 LADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ DF + S R L + + P R ++ + L+++LKHTP H D
Sbjct: 232 VQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPD 281
>AB209852-1|BAD93089.1| 624|Homo sapiens Neuroepithelial cell
transforming gene 1 protein variant protein.
Length = 624
Score = 46.8 bits (106), Expect = 5e-04
Identities = 37/170 (21%), Positives = 74/170 (43%), Gaps = 7/170 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
++RR+ + + E + L+ Y P+ + S I++ ++ +F L + H
Sbjct: 201 EIRRQEAIYEMSRGEQDLIEDLKLARKAYHDPMLKLS--IMSEEELTHIFGDLDSYIPLH 258
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSA 238
T + + + E+IG + +S + L+ Y + +N A L + K+
Sbjct: 259 EDLLTRIGEATKPDGTVEQIGHILVSWLPR---LNAYRGYCSNQLAAKALLD-QKKQDPR 314
Query: 239 LADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ DF + S R L + + P R ++ + L+++LKHTP H D
Sbjct: 315 VQDFLQRCLESPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPD 364
>AB067496-1|BAB67802.2| 1287|Homo sapiens KIAA1909 protein protein.
Length = 1287
Score = 46.4 bits (105), Expect = 6e-04
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHL- 179
R RH++A +I +E Y+ L ++++Y +E K +F L + H
Sbjct: 821 RLRHIMAEMIATEREYIRCLGYVIDNYFPEMERMDLPQGLRGKHHVIFGNLEKLHDFHQQ 880
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
HF L C +G FL + + +YS + A + S +
Sbjct: 881 HFLRELERCQHC---PLAVGRSFLRHEEQFGMYVIYSK-----NKPQSDALLSSHGNA-- 930
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHA 286
FFK KQ D++ +++PVQR ++ + LQDLLK G A
Sbjct: 931 --FFKDKQRELGDKMDLASYLLRPVQRVAKYALLLQDLLKEASCGLA 975
>BC116186-1|AAI16187.1| 1721|Homo sapiens intersectin 1 (SH3 domain
protein) protein.
Length = 1721
Score = 46.0 bits (104), Expect = 8e-04
Identities = 38/171 (22%), Positives = 81/171 (47%), Gaps = 9/171 (5%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R+ + +I +E +YV LQ + ++KPL ES +L ++ +F +++ C++
Sbjct: 1237 KRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESE--LLTEKEVAMIFVNWKELIMCNIK 1294
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
AL + EK+ + A L +I S + A + ++
Sbjct: 1295 LLKALR--VRKKMSGEKMPVKMIGDILSAQ-LPHMQPYIRFCSRQLNGAALIQQKTDEAP 1351
Query: 241 DFFK-VKQISAHDR---LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
DF + VK+++ R + ++KP+QR ++ + ++++L++TP H D
Sbjct: 1352 DFKEFVKRLAMDPRCRGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPD 1402
>BC116185-1|AAI16186.1| 1716|Homo sapiens ITSN1 protein protein.
Length = 1716
Score = 46.0 bits (104), Expect = 8e-04
Identities = 38/171 (22%), Positives = 81/171 (47%), Gaps = 9/171 (5%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R+ + +I +E +YV LQ + ++KPL ES +L ++ +F +++ C++
Sbjct: 1232 KRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESE--LLTEKEVAMIFVNWKELIMCNIK 1289
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
AL + EK+ + A L +I S + A + ++
Sbjct: 1290 LLKALR--VRKKMSGEKMPVKMIGDILSAQ-LPHMQPYIRFCSRQLNGAALIQQKTDEAP 1346
Query: 241 DFFK-VKQISAHDR---LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
DF + VK+++ R + ++KP+QR ++ + ++++L++TP H D
Sbjct: 1347 DFKEFVKRLAMDPRCRGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPD 1397
>AF114487-1|AAD29952.1| 1721|Homo sapiens intersectin long isoform
protein.
Length = 1721
Score = 46.0 bits (104), Expect = 8e-04
Identities = 38/171 (22%), Positives = 81/171 (47%), Gaps = 9/171 (5%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R+ + +I +E +YV LQ + ++KPL ES +L ++ +F +++ C++
Sbjct: 1237 KRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESE--LLTEKEVAMIFVNWKELIMCNIK 1294
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
AL + EK+ + A L +I S + A + ++
Sbjct: 1295 LLKALR--VRKKMSGEKMPVKMIGDILSAQ-LPHMQPYIRFCSRQLNGAALIQQKTDEAP 1351
Query: 241 DFFK-VKQISAHDR---LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
DF + VK+++ R + ++KP+QR ++ + ++++L++TP H D
Sbjct: 1352 DFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPD 1402
>AF064244-1|AAC78611.1| 1721|Homo sapiens intersectin long form
protein.
Length = 1721
Score = 45.6 bits (103), Expect = 0.001
Identities = 38/171 (22%), Positives = 80/171 (46%), Gaps = 9/171 (5%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R+ + +I +E +YV LQ + ++KPL ES +L ++ +F +++ C++
Sbjct: 1237 KRQGYIHELIVTEENYVNDLQLVTEIFQKPLMESE--LLTEKEVAMIFVNWKELIMCNIK 1294
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
AL + EK+ + A L +I S + A + ++
Sbjct: 1295 LLKALR--VRKKMSGEKMPVKMIGDILSAQ-LPHMQPYIRFCSRQLNGAALIQQKTDEAP 1351
Query: 241 DFFK-VKQISAHDR---LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
DF + VK++ R + ++KP+QR ++ + ++++L++TP H D
Sbjct: 1352 DFKEFVKRLEMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPD 1402
>AF248540-1|AAF63600.1| 1681|Homo sapiens intersectin 2 protein.
Length = 1681
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/176 (19%), Positives = 83/176 (47%), Gaps = 13/176 (7%)
Query: 118 VQLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQC 177
++ +R+ + +I +E Y+A LQ +V ++K + ES L ++ +F +++
Sbjct: 1190 IERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESG--FLTEGEMALIFVNWKELIMS 1247
Query: 178 HLHFRTALADCAQTWDRD---EKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESK 234
+ AL +T + IG++ + S + Y F + L + ++
Sbjct: 1248 NTKLLKALRVRKKTGGEKMPVQMIGDILAAELSH---MQAYIRFCSCQLNGAALLQQKTD 1304
Query: 235 RKSALADFFKVKQISAHDR---LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ +F +K++++ R + ++KP+QR ++ + ++ +L++TP HAD
Sbjct: 1305 EDTDFKEF--LKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHAD 1358
>AF182198-1|AAF59903.1| 1696|Homo sapiens intersectin 2 long isoform
protein.
Length = 1696
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/176 (19%), Positives = 83/176 (47%), Gaps = 13/176 (7%)
Query: 118 VQLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQC 177
++ +R+ + +I +E Y+A LQ +V ++K + ES L ++ +F +++
Sbjct: 1205 IERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESG--FLTEGEMALIFVNWKELIMS 1262
Query: 178 HLHFRTALADCAQTWDRD---EKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESK 234
+ AL +T + IG++ + S + Y F + L + ++
Sbjct: 1263 NTKLLKALRVRKKTGGEKMPVQMIGDILAAELSH---MQAYIRFCSCQLNGAALLQQKTD 1319
Query: 235 RKSALADFFKVKQISAHDR---LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ +F +K++++ R + ++KP+QR ++ + ++ +L++TP HAD
Sbjct: 1320 EDTDFKEF--LKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHAD 1373
>AB033082-1|BAA86570.1| 1676|Homo sapiens KIAA1256 protein protein.
Length = 1676
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/176 (19%), Positives = 83/176 (47%), Gaps = 13/176 (7%)
Query: 118 VQLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQC 177
++ +R+ + +I +E Y+A LQ +V ++K + ES L ++ +F +++
Sbjct: 1185 IERKRQGYIHELIQTEERYMADLQLVVEVFQKRMAESG--FLTEGEMALIFVNWKELIMS 1242
Query: 178 HLHFRTALADCAQTWDRD---EKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESK 234
+ AL +T + IG++ + S + Y F + L + ++
Sbjct: 1243 NTKLLKALRVRKKTGGEKMPVQMIGDILAAELSH---MQAYIRFCSCQLNGAALLQQKTD 1299
Query: 235 RKSALADFFKVKQISAHDR---LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ +F +K++++ R + ++KP+QR ++ + ++ +L++TP HAD
Sbjct: 1300 EDTDFKEF--LKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPESHAD 1353
>X12556-1|CAA31069.1| 925|Homo sapiens protein ( Human mRNA for dbl
proto-oncogene. ).
Length = 925
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 496 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 554
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 555 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 603
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 604 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 649
>U16296-1|AAA98443.1| 1591|Homo sapiens TIAM1 protein protein.
Length = 1591
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/168 (21%), Positives = 75/168 (44%), Gaps = 11/168 (6%)
Query: 123 RHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFR 182
R V+ ++ +E +YV L L+ Y KPL++ + L ++ LF L ++++ + F
Sbjct: 1042 RKVICELLETERTYVKDLNCLMERYLKPLQKET--FLTQDELDVLFGNLTEMVEFQVEFL 1099
Query: 183 TALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS----VAMELAK--MES 233
L D ++ EK+ + FS Y+D +S + ++ K +++
Sbjct: 1100 KTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCAIHTKVPKVLVKA 1159
Query: 234 KRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K +A F + + ++KP+QR ++ + L++L T
Sbjct: 1160 KTDTAFKAFLDAQNPKQQHSSTLESYLIKPIQRILKYPLLLRELFALT 1207
>D25304-1|BAA04985.1| 773|Homo sapiens KIAA0006 protein.
Length = 773
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/163 (22%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +E Y LQ L+ Y +PL+ ++ L+ ++ +L ++ A
Sbjct: 242 VLQNILDTEKEYAKELQSLLVTYLRPLQSNNN--LSTVEVTSLLGNFEEVCTFQQTLCQA 299
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C++ + K+G LS +Y + N A+ + S L F +
Sbjct: 300 LEECSKFPENQHKVGGCLLSLMPH--FKSMYLAYCANHPSAVNVLTQHSDE---LEQFME 354
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ S+ L + KP R +++ LQ+L +H H D
Sbjct: 355 NQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPD 397
>BC043505-1|AAH43505.1| 538|Homo sapiens ARHGEF6 protein protein.
Length = 538
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/163 (22%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +E Y LQ L+ Y +PL+ ++ L+ ++ +L ++ A
Sbjct: 91 VLQNILDTEKEYAKELQSLLVTYLRPLQSNNN--LSTVEVTSLLGNFEEVCTFQQTLCQA 148
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C++ + K+G LS +Y + N A+ + S L F +
Sbjct: 149 LEECSKFPENQHKVGGCLLSLMPH--FKSMYLAYCANHPSAVNVLTQHSDE---LEQFME 203
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ S+ L + KP R +++ LQ+L +H H D
Sbjct: 204 NQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPD 246
>BC039856-1|AAH39856.1| 776|Homo sapiens Rac/Cdc42 guanine
nucleotide exchange factor (GEF) 6 protein.
Length = 776
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/163 (22%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +E Y LQ L+ Y +PL+ ++ L+ ++ +L ++ A
Sbjct: 245 VLQNILDTEKEYAKELQSLLVTYLRPLQSNNN--LSTVEVTSLLGNFEEVCTFQQTLCQA 302
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C++ + K+G LS +Y + N A+ + S L F +
Sbjct: 303 LEECSKFPENQHKVGGCLLSLMPH--FKSMYLAYCANHPSAVNVLTQHSDE---LEQFME 357
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ S+ L + KP R +++ LQ+L +H H D
Sbjct: 358 NQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPD 400
>AL683813-1|CAI39443.1| 776|Homo sapiens Rac/Cdc42 guanine
nucleotide exchange factor (GEF) 6 protein.
Length = 776
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/163 (22%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +E Y LQ L+ Y +PL+ ++ L+ ++ +L ++ A
Sbjct: 245 VLQNILDTEKEYAKELQSLLVTYLRPLQSNNN--LSTVEVTSLLGNFEEVCTFQQTLCQA 302
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C++ + K+G LS +Y + N A+ + S L F +
Sbjct: 303 LEECSKFPENQHKVGGCLLSLMPH--FKSMYLAYCANHPSAVNVLTQHSDE---LEQFME 357
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ S+ L + KP R +++ LQ+L +H H D
Sbjct: 358 NQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPD 400
>AL161777-3|CAI39715.1| 1070|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 1070
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 641 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 699
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 700 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 748
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 749 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 794
>AL135783-5|CAI42903.1| 622|Homo sapiens Rac/Cdc42 guanine
nucleotide exchange factor (GEF) 6 protein.
Length = 622
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/163 (22%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +E Y LQ L+ Y +PL+ ++ L+ ++ +L ++ A
Sbjct: 91 VLQNILDTEKEYAKELQSLLVTYLRPLQSNNN--LSTVEVTSLLGNFEEVCTFQQTLCQA 148
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C++ + K+G LS +Y + N A+ + S L F +
Sbjct: 149 LEECSKFPENQHKVGGCLLSLMPH--FKSMYLAYCANHPSAVNVLTQHSDE---LEQFME 203
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ S+ L + KP R +++ LQ+L +H H D
Sbjct: 204 NQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPD 246
>AL135783-1|CAI42899.1| 776|Homo sapiens Rac/Cdc42 guanine
nucleotide exchange factor (GEF) 6 protein.
Length = 776
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/163 (22%), Positives = 68/163 (41%), Gaps = 7/163 (4%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTA 184
V+ I+ +E Y LQ L+ Y +PL+ ++ L+ ++ +L ++ A
Sbjct: 245 VLQNILDTEKEYAKELQSLLVTYLRPLQSNNN--LSTVEVTSLLGNFEEVCTFQQTLCQA 302
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L +C++ + K+G LS +Y + N A+ + S L F +
Sbjct: 303 LEECSKFPENQHKVGGCLLSLMPH--FKSMYLAYCANHPSAVNVLTQHSDE---LEQFME 357
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
+ S+ L + KP R +++ LQ+L +H H D
Sbjct: 358 NQGASSPGILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPD 400
>AL117234-1|CAB55301.1| 985|Homo sapiens hypothetical protein
protein.
Length = 985
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 556 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 614
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 615 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 663
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 664 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 709
>AL033403-7|CAA21955.1| 925|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 925
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 496 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 554
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 555 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 603
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 604 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 649
>AL033403-6|CAI42107.1| 941|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 941
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 512 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 570
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 571 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 619
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 620 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 665
>AL033403-5|CAI42108.1| 860|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 860
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 496 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 554
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 555 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 603
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 604 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 649
>AL033403-4|CAI42106.1| 528|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 528
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 99 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 157
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 158 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 206
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 207 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 252
>AL033403-2|CAI42104.1| 1070|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 1070
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 641 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 699
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 700 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 748
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 749 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 794
>AB085902-1|BAC41201.1| 941|Homo sapiens DBL proto-oncogene
splicing variant 2 protein.
Length = 941
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 512 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 570
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 571 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 619
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 620 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 665
>AB085901-1|BAC41200.1| 860|Homo sapiens DBL proto-oncogene
splicing variant 1 protein.
Length = 860
Score = 44.0 bits (99), Expect = 0.003
Identities = 41/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 496 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 554
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 555 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 603
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 604 KYSECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 649
>J03639-1|AAA52172.1| 478|Homo sapiens MCF2 protein.
Length = 478
Score = 43.2 bits (97), Expect = 0.006
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I + H
Sbjct: 51 HVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYEFH 109
Query: 179 LH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
F ++L +CA E++G FL +Y+ + N + + RK
Sbjct: 110 NDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----RKY 158
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 159 SECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 202
>BC117196-1|AAI17197.1| 1591|Homo sapiens T-cell lymphoma invasion and
metastasis 1 protein.
Length = 1591
Score = 43.2 bits (97), Expect = 0.006
Identities = 35/168 (20%), Positives = 72/168 (42%), Gaps = 11/168 (6%)
Query: 123 RHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFR 182
R V+ ++ +E +YV L L+ Y KPL++ + L ++ LF L ++++ + F
Sbjct: 1042 RKVICELLETERTYVKDLNCLMERYLKPLQKET--FLTQDELDVLFGNLTEMVEFQVEFL 1099
Query: 183 TALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKMES 233
L D ++ EK+ + FS Y+D +S + +++
Sbjct: 1100 KTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKA 1159
Query: 234 KRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K +A F + + ++KP+QR ++ + L++L T
Sbjct: 1160 KTDTAFKAFLDAQNPKQQHSSTLESYLIKPIQRILKYPLLLRELFALT 1207
>BC117192-1|AAI17193.1| 1591|Homo sapiens T-cell lymphoma invasion and
metastasis 1 protein.
Length = 1591
Score = 43.2 bits (97), Expect = 0.006
Identities = 35/168 (20%), Positives = 72/168 (42%), Gaps = 11/168 (6%)
Query: 123 RHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFR 182
R V+ ++ +E +YV L L+ Y KPL++ + L ++ LF L ++++ + F
Sbjct: 1042 RKVICELLETERTYVKDLNCLMERYLKPLQKET--FLTQDELDVLFGNLTEMVEFQVEFL 1099
Query: 183 TALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKMES 233
L D ++ EK+ + FS Y+D +S + +++
Sbjct: 1100 KTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKA 1159
Query: 234 KRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K +A F + + ++KP+QR ++ + L++L T
Sbjct: 1160 KTDTAFKAFLDAQNPKQQHSSTLESYLIKPIQRILKYPLLLRELFALT 1207
>BC066979-1|AAH66979.1| 626|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 626
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 24 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFRKV 81
Query: 181 FRTALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKM 231
F L D + ++ E + FS Y+D +S + ++
Sbjct: 82 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLE 141
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 142 RAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 191
>AL596202-1|CAI14404.1| 1046|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 1046
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 444 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFQKV 501
Query: 181 FRTALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKM 231
F L D + ++ E + FS Y+D +S + ++
Sbjct: 502 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLE 561
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 562 RAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 611
>AL355343-1|CAH73978.1| 1046|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 1046
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 444 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFQKV 501
Query: 181 FRTALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKM 231
F L D + ++ E + FS Y+D +S + ++
Sbjct: 502 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLE 561
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 562 RAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 611
>AL139101-3|CAI20508.1| 1046|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 1046
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 444 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFQKV 501
Query: 181 FRTALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKM 231
F L D + ++ E + FS Y+D +S + ++
Sbjct: 502 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLE 561
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 562 RAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 611
>AL033403-3|CAI42105.1| 428|Homo sapiens MCF.2 cell line derived
transforming sequence protein.
Length = 428
Score = 43.2 bits (97), Expect = 0.006
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I + H
Sbjct: 1 HVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYEFH 59
Query: 179 LH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
F ++L +CA E++G FL +Y+ + N + + RK
Sbjct: 60 NDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----RKY 108
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 109 SECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 152
>AF120324-1|AAF05901.1| 626|Homo sapiens T-cell lymphoma invasion
and metastasis 2 short protein.
Length = 626
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 24 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFQKV 81
Query: 181 FRTALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKM 231
F L D + ++ E + FS Y+D +S + ++
Sbjct: 82 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLE 141
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 142 RAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 191
>AF120323-1|AAF05900.1| 1077|Homo sapiens T-cell lymphoma invasion
and metastasis 2 protein.
Length = 1077
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 475 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFQKV 532
Query: 181 FRTALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKM 231
F L D + ++ E + FS Y+D +S + ++
Sbjct: 533 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLE 592
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 593 RAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 642
>AB209679-1|BAD92916.1| 435|Homo sapiens MCF.2 cell line derived
transforming sequence variant protein.
Length = 435
Score = 43.2 bits (97), Expect = 0.006
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Query: 124 HVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQCH 178
HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I + H
Sbjct: 8 HVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYEFH 66
Query: 179 LH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKS 237
F ++L +CA E++G FL +Y+ + N + + RK
Sbjct: 67 NDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----RKY 115
Query: 238 ALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+ FF+ Q RL ++KPVQR ++ + L++LLK++
Sbjct: 116 SECAFFQECQRKLKHRLRLDSYLLKPVQRITKYQLLLKELLKYS 159
>AB209674-1|BAD92911.1| 1947|Homo sapiens T-cell lymphoma invasion and
metastasis 2 variant protein.
Length = 1947
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 1345 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFQKV 1402
Query: 181 FRTALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKM 231
F L D + ++ E + FS Y+D +S + ++
Sbjct: 1403 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLE 1462
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 1463 RAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 1512
>AB095936-1|BAC23112.2| 1715|Homo sapiens KIAA2016 protein protein.
Length = 1715
Score = 43.2 bits (97), Expect = 0.006
Identities = 38/170 (22%), Positives = 73/170 (42%), Gaps = 11/170 (6%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 1113 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFQKV 1170
Query: 181 FRTALAD---CAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFS------VAMELAKM 231
F L D + ++ E + FS Y+D +S + ++
Sbjct: 1171 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYADHFKLYSGFCANHIKVQKVLE 1230
Query: 232 ESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 1231 RAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 1280
>X13230-1|CAA31617.1| 567|Homo sapiens protein ( Human mRNA for
MCF.2 protein 3'-end. ).
Length = 567
Score = 42.3 bits (95), Expect = 0.010
Identities = 40/166 (24%), Positives = 75/166 (45%), Gaps = 18/166 (10%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-----PAILNASKIQTLFHRLPDILQ 176
+ HV+ +I +E YV L ++ Y+ ++ P +L K LF + +I +
Sbjct: 138 KNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDLMPPLLRNKK-DILFGNMAEIYE 196
Query: 177 CHLH-FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKR 235
H F ++L +CA E++G FL +Y+ + N + + R
Sbjct: 197 FHNDIFLSSLENCAHA---PERVGPCFLERKDD---FQMYAKYCQNKPRSETIW-----R 245
Query: 236 KSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
K + FF+ Q RL ++KPVQ+ ++ + L++LLK++
Sbjct: 246 KYSECAFFQECQRKLKHRLRLDSYLLKPVQQITKYQLLLKELLKYS 291
>AK125979-1|BAC86373.1| 738|Homo sapiens (Hapip). protein.
Length = 738
Score = 42.3 bits (95), Expect = 0.010
Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 14/161 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R V+ ++ +E YV L +V + K +EE K + +F + I H F
Sbjct: 271 RMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKDKIVFGNIHQIYDWHKDF 330
Query: 182 RTA-LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
A L C Q DR + ++F+ K L +Y + N E E A
Sbjct: 331 FLAELEKCIQEQDR---LAQLFIKHERK---LHIYVWYCQN-KPRSEYIVAEYD-----A 378
Query: 241 DFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
F +VKQ + RL+ ++KP+QR ++ + L+D L+++
Sbjct: 379 YFEEVKQ-EINQRLTLSDFLIKPIQRITKYQLLLKDFLRYS 418
>AB011422-1|BAA76314.1| 1289|Homo sapiens Trad protein.
Length = 1289
Score = 42.3 bits (95), Expect = 0.010
Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 14/161 (8%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHF 181
R V+ ++ +E YV L +V + K +EE K + +F + I H F
Sbjct: 233 RMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKGVPEDMRGKDKIVFGNIHQIYDWHKDF 292
Query: 182 RTA-LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALA 240
A L C Q DR + ++F+ K L +Y + N E E A
Sbjct: 293 FLAELEKCIQEQDR---LAQLFIKHERK---LHIYVWYCQN-KPRSEYIVAEYD-----A 340
Query: 241 DFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
F +VKQ + RL+ ++KP+QR ++ + L+D L+++
Sbjct: 341 YFEEVKQ-EINQRLTLSDFLIKPIQRITKYQLLLKDFLRYS 380
>AK125459-1|BAC86170.1| 1268|Homo sapiens protein ( Homo sapiens
cDNA FLJ43470 fis, clone OCBBF2037547, highly similar
to Homo sapiens T-cell lymphoma invasion and metastasis
2 (TIAM2). ).
Length = 1268
Score = 41.1 bits (92), Expect = 0.023
Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 13/171 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
R R V+ ++ +E SYV L L Y +PL+ + L ++++LF LP++L+
Sbjct: 637 RLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNET--FLTQDEMESLFGSLPEMLEFQKV 694
Query: 181 FRTALADCA------QTWDRDEKIGEVFL----SAFSKAVVLDVYSDFINNFSVAMELAK 230
F L D T + + ++ S A +YS F N + ++
Sbjct: 695 FLETLEDGISASSDFNTLETPSQFRKLLFPLGGSFLYYADHFKLYSGFCAN-HIKVQKVL 753
Query: 231 MESKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
+K A F + + + ++KPVQR ++ + L++L+ T
Sbjct: 754 ERAKTDKAFKAFLDARNPTKQHSSTLESYLIKPVQRVLKYPLLLKELVSLT 804
>U02082-1|AAA18010.1| 519|Homo sapiens guanine nucleotide
regulatory protein protein.
Length = 519
Score = 40.3 bits (90), Expect = 0.040
Identities = 39/160 (24%), Positives = 70/160 (43%), Gaps = 5/160 (3%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
+I SE SY+ +L V+ ++ L S A L+ + Q LF RL D+ F + L +
Sbjct: 104 LIVSEASYLRSLNIAVDHFQ--LSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEEN 161
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFF-KVKQ 247
+ ++ +V L+ VY ++ N + + S + K++
Sbjct: 162 FENNIFSFQVCDVVLNHAPD--FRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLES 219
Query: 248 ISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
RLS ++ P QR + + LQ++LK T PG ++
Sbjct: 220 DPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSE 259
>BC014555-1|AAH14555.1| 519|Homo sapiens ARHGEF5 protein protein.
Length = 519
Score = 40.3 bits (90), Expect = 0.040
Identities = 39/160 (24%), Positives = 70/160 (43%), Gaps = 5/160 (3%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
+I SE SY+ +L V+ ++ L S A L+ + Q LF RL D+ F + L +
Sbjct: 104 LIVSEASYLRSLNIAVDHFQ--LSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEEN 161
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFF-KVKQ 247
+ ++ +V L+ VY ++ N + + S + K++
Sbjct: 162 FENNIFSFQVCDVVLNHAPD--FRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLES 219
Query: 248 ISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
RLS ++ P QR + + LQ++LK T PG ++
Sbjct: 220 DPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSE 259
>BC011839-1|AAH11839.1| 519|Homo sapiens ARHGEF5 protein protein.
Length = 519
Score = 40.3 bits (90), Expect = 0.040
Identities = 39/160 (24%), Positives = 70/160 (43%), Gaps = 5/160 (3%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
+I SE SY+ +L V+ ++ L S A L+ + Q LF RL D+ F + L +
Sbjct: 104 LIVSEASYLRSLNIAVDHFQ--LSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEEN 161
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFF-KVKQ 247
+ ++ +V L+ VY ++ N + + S + K++
Sbjct: 162 FENNIFSFQVCDVVLNHAPD--FRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLES 219
Query: 248 ISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
RLS ++ P QR + + LQ++LK T PG ++
Sbjct: 220 DPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSE 259
>BC010046-1|AAH10046.1| 519|Homo sapiens ARHGEF5 protein protein.
Length = 519
Score = 40.3 bits (90), Expect = 0.040
Identities = 39/160 (24%), Positives = 70/160 (43%), Gaps = 5/160 (3%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
+I SE SY+ +L V+ ++ L S A L+ + Q LF RL D+ F + L +
Sbjct: 104 LIVSEASYLRSLNIAVDHFQ--LSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEEN 161
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFF-KVKQ 247
+ ++ +V L+ VY ++ N + + S + K++
Sbjct: 162 FENNIFSFQVCDVVLNHAPD--FRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLES 219
Query: 248 ISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
RLS ++ P QR + + LQ++LK T PG ++
Sbjct: 220 DPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSE 259
>AY196211-1|AAP34307.1| 1577|Homo sapiens TUBA protein.
Length = 1577
Score = 40.3 bits (90), Expect = 0.040
Identities = 35/177 (19%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R V+ ++ +E Y+ L+ + P++++ ++ + LF + +++
Sbjct: 784 KRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNID---FEGLFGNMQMVIKVSKQ 840
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELA-------KMES 233
AL + + +G VFL + + Y + N A+ L K++
Sbjct: 841 LLAAL-------EISDAVGPVFLG--HRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQK 891
Query: 234 KRKSALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRV 289
+ +LAD + + + ++ ++KPVQR ++ + L +LL TP H D+V
Sbjct: 892 HLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKV 948
>AL732437-4|CAI11032.1| 160|Homo sapiens neuroepithelial cell
transforming gene 1 protein.
Length = 160
Score = 40.3 bits (90), Expect = 0.040
Identities = 33/160 (20%), Positives = 69/160 (43%), Gaps = 9/160 (5%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
+ H E + ++R + + L+ ++ + ++ +F L + H T + +
Sbjct: 2 VAHDETGGLLPIKRTI----RVLDVNNQSFREQEELTHIFGDLDSYIPLHEDLLTRIGEA 57
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFKVKQI 248
+ E+IG + +S + L+ Y + +N A L + K+ + DF +
Sbjct: 58 TKPDGTVEQIGHILVSWLPR---LNAYRGYCSNQLAAKALLD-QKKQDPRVQDFLQRCLE 113
Query: 249 SAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
S R L + + P R ++ + L+++LKHTP H D
Sbjct: 114 SPFSRKLDLWSFLDIPRSRLVKYPLLLKEILKHTPKEHPD 153
>AL627434-2|CAI13197.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 40.3 bits (90), Expect = 0.040
Identities = 35/177 (19%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R V+ ++ +E Y+ L+ + P++++ ++ + LF + +++
Sbjct: 784 KRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNID---FEGLFGNMQMVIKVSKQ 840
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELA-------KMES 233
AL + + +G VFL + + Y + N A+ L K++
Sbjct: 841 LLAAL-------EISDAVGPVFLG--HRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQK 891
Query: 234 KRKSALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRV 289
+ +LAD + + + ++ ++KPVQR ++ + L +LL TP H D+V
Sbjct: 892 HLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKV 948
>AL441886-1|CAI13076.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 40.3 bits (90), Expect = 0.040
Identities = 35/177 (19%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R V+ ++ +E Y+ L+ + P++++ ++ + LF + +++
Sbjct: 784 KRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNID---FEGLFGNMQMVIKVSKQ 840
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELA-------KMES 233
AL + + +G VFL + + Y + N A+ L K++
Sbjct: 841 LLAAL-------EISDAVGPVFLG--HRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQK 891
Query: 234 KRKSALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRV 289
+ +LAD + + + ++ ++KPVQR ++ + L +LL TP H D+V
Sbjct: 892 HLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKV 948
>AL392107-2|CAI11009.1| 1601|Homo sapiens novel protein protein.
Length = 1601
Score = 40.3 bits (90), Expect = 0.040
Identities = 35/177 (19%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R V+ ++ +E Y+ L+ + P++++ ++ + LF + +++
Sbjct: 784 KRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNID---FEGLFGNMQMVIKVSKQ 840
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELA-------KMES 233
AL + + +G VFL + + Y + N A+ L K++
Sbjct: 841 LLAAL-------EISDAVGPVFLG--HRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQK 891
Query: 234 KRKSALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRV 289
+ +LAD + + + ++ ++KPVQR ++ + L +LL TP H D+V
Sbjct: 892 HLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKV 948
>AK160365-1|BAD18708.1| 1651|Homo sapiens FLJ00261 protein protein.
Length = 1651
Score = 40.3 bits (90), Expect = 0.040
Identities = 39/160 (24%), Positives = 70/160 (43%), Gaps = 5/160 (3%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
+I SE SY+ +L V+ ++ L S A L+ + Q LF RL D+ F + L +
Sbjct: 1236 LIVSEASYLRSLNIAVDHFQ--LSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEEN 1293
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFF-KVKQ 247
+ ++ +V L+ VY ++ N + + S + K++
Sbjct: 1294 FENNIFSFQVCDVVLNHAPD--FRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLES 1351
Query: 248 ISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
RLS ++ P QR + + LQ++LK T PG ++
Sbjct: 1352 DPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSE 1391
>AC004534-1|AAC12958.1| 519|Homo sapiens guanine nucleotide
regulatory protein protein.
Length = 519
Score = 40.3 bits (90), Expect = 0.040
Identities = 39/160 (24%), Positives = 70/160 (43%), Gaps = 5/160 (3%)
Query: 129 IIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLHFRTALADC 188
+I SE SY+ +L V+ ++ L S A L+ + Q LF RL D+ F + L +
Sbjct: 104 LIVSEASYLRSLNIAVDHFQ--LSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEEN 161
Query: 189 AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFF-KVKQ 247
+ ++ +V L+ VY ++ N + + S + K++
Sbjct: 162 FENNIFSFQVCDVVLNHAPD--FRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLES 219
Query: 248 ISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
RLS ++ P QR + + LQ++LK T PG ++
Sbjct: 220 DPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSE 259
>AB023227-1|BAA76854.1| 1315|Homo sapiens KIAA1010 protein protein.
Length = 1315
Score = 40.3 bits (90), Expect = 0.040
Identities = 35/177 (19%), Positives = 77/177 (43%), Gaps = 20/177 (11%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R V+ ++ +E Y+ L+ + P++++ ++ + LF + +++
Sbjct: 522 KRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNID---FEGLFGNMQMVIKVSKQ 578
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELA-------KMES 233
AL + + +G VFL + + Y + N A+ L K++
Sbjct: 579 LLAAL-------EISDAVGPVFLG--HRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQK 629
Query: 234 KRKSALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRV 289
+ +LAD + + + ++ ++KPVQR ++ + L +LL TP H D+V
Sbjct: 630 HLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKV 686
>BC077721-1|AAH77721.1| 1030|Homo sapiens ARHGEF18 protein protein.
Length = 1030
Score = 39.1 bits (87), Expect = 0.093
Identities = 39/180 (21%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 120 LRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHL 179
++R+ V+ ++ +E +V TL+ ++ Y + L+E ++ I LF D+L+ H
Sbjct: 100 VKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEELQ--FSSKAIGRLFPCADDLLETHS 157
Query: 180 HFRTALADCAQT-----WDRD---EKIGEVFLSAFS---KAVVLDVYSDFINNFSVAMEL 228
HF L + Q DR+ +KIG++ + FS + + Y F + + A+
Sbjct: 158 HFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKEKYGVFCSGHNEAVSH 217
Query: 229 AKMESKRKSALADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
K+ ++ + K+ S RL ++ QR ++ + ++ ++++T G D
Sbjct: 218 YKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTED 277
>BC041628-1|AAH41628.1| 823|Homo sapiens DNMBP protein protein.
Length = 823
Score = 39.1 bits (87), Expect = 0.093
Identities = 35/177 (19%), Positives = 76/177 (42%), Gaps = 20/177 (11%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R V+ ++ +E Y+ L+ + P++++ ++ + LF +++
Sbjct: 30 KRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNID---FEGLFGNTQMVIKVSKQ 86
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELA-------KMES 233
AL + + +G VFL + + Y + N A+ L K++
Sbjct: 87 LLAAL-------EISDAVGPVFLG--HRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQK 137
Query: 234 KRKSALADFFKV-KQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADRV 289
+ +LAD + + + ++ ++KPVQR ++ + L +LL TP H D+V
Sbjct: 138 HLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKV 194
>AK127045-1|BAC86801.1| 1173|Homo sapiens HO-GEF). protein.
Length = 1173
Score = 39.1 bits (87), Expect = 0.093
Identities = 39/180 (21%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 120 LRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHL 179
++R+ V+ ++ +E +V TL+ ++ Y + L+E ++ I LF D+L+ H
Sbjct: 258 VKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEELQ--FSSKAIGRLFPCADDLLETHS 315
Query: 180 HFRTALADCAQT-----WDRD---EKIGEVFLSAFS---KAVVLDVYSDFINNFSVAMEL 228
HF L + Q DR+ +KIG++ + FS + + Y F + + A+
Sbjct: 316 HFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKEKYGVFCSGHNEAVSH 375
Query: 229 AKMESKRKSALADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
K+ ++ + K+ S RL ++ QR ++ + ++ ++++T G D
Sbjct: 376 YKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTED 435
>AK027713-1|BAB55317.1| 359|Homo sapiens protein ( Homo sapiens
cDNA FLJ14807 fis, clone NT2RP4001760, weakly similar to
PUTATIVE RHO/RAC GUANINE NUCLEOTIDE EXCHANGE FACTOR. ).
Length = 359
Score = 39.1 bits (87), Expect = 0.093
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 234 KRKSALADFFKVKQISAH-DRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHADR 288
K+K F K+ Q R S L+++PVQR P + L DL KHT + D+
Sbjct: 11 KQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDK 66
>AB011093-1|BAA25447.1| 1050|Homo sapiens KIAA0521 protein protein.
Length = 1050
Score = 39.1 bits (87), Expect = 0.093
Identities = 39/180 (21%), Positives = 83/180 (46%), Gaps = 14/180 (7%)
Query: 120 LRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHL 179
++R+ V+ ++ +E +V TL+ ++ Y + L+E ++ I LF D+L+ H
Sbjct: 135 VKRQDVLYELMQTEVHHVRTLKIMLKVYSRALQEELQ--FSSKAIGRLFPCADDLLETHS 192
Query: 180 HFRTALADCAQT-----WDRD---EKIGEVFLSAFS---KAVVLDVYSDFINNFSVAMEL 228
HF L + Q DR+ +KIG++ + FS + + Y F + + A+
Sbjct: 193 HFLARLKERRQESLEEGSDRNYVIQKIGDLLVQQFSGENGERMKEKYGVFCSGHNEAVSH 252
Query: 229 AKMESKRKSALADFF-KVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
K+ ++ + K+ S RL ++ QR ++ + ++ ++++T G D
Sbjct: 253 YKLLLQQNKKFQNLIKKIGNFSIVRRLGVQECILLVTQRITKYPVLVERIIQNTEAGTED 312
>BC082974-1|AAH82974.1| 1151|Homo sapiens PLEKHG4 protein protein.
Length = 1151
Score = 38.7 bits (86), Expect = 0.12
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 13/160 (8%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-PAILNASKIQTLFHRLPDILQCHL 179
R + V+A ++ +E YV L+ + +Y L+ P L + LF L + H
Sbjct: 692 RLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAH-LFGNLEKLRDFHC 750
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
HF L + ++ FL V +Y+ + N + ++ S
Sbjct: 751 HF--FLRELEACTRHPPRVAYAFLR---HRVQFGMYALYSKN------KPRSDALMSSYG 799
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLK 279
FFK KQ + D L ++KP+QR ++ + LQ+L +
Sbjct: 800 HTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELAR 839
>BC063501-1|AAH63501.1| 1191|Homo sapiens PLEKHG4 protein protein.
Length = 1191
Score = 38.7 bits (86), Expect = 0.12
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 13/160 (8%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-PAILNASKIQTLFHRLPDILQCHL 179
R + V+A ++ +E YV L+ + +Y L+ P L + LF L + H
Sbjct: 732 RLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAH-LFGNLEKLRDFHC 790
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
HF L + ++ FL V +Y+ + N + ++ S
Sbjct: 791 HF--FLRELEACTRHPPRVAYAFLR---HRVQFGMYALYSKN------KPRSDALMSSYG 839
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLK 279
FFK KQ + D L ++KP+QR ++ + LQ+L +
Sbjct: 840 HTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELAR 879
>BC054486-1|AAH54486.1| 1110|Homo sapiens PLEKHG4 protein protein.
Length = 1110
Score = 38.7 bits (86), Expect = 0.12
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 13/160 (8%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-PAILNASKIQTLFHRLPDILQCHL 179
R + V+A ++ +E YV L+ + +Y L+ P L + LF L + H
Sbjct: 651 RLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAH-LFGNLEKLRDFHC 709
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
HF L + ++ FL V +Y+ + N + ++ S
Sbjct: 710 HF--FLRELEACTRHPPRVAYAFLR---HRVQFGMYALYSKN------KPRSDALMSSYG 758
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLK 279
FFK KQ + D L ++KP+QR ++ + LQ+L +
Sbjct: 759 HTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELAR 798
>AK125163-1|BAC86068.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ43173 fis, clone FCBBF3007540, weakly similar
to GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS. ).
Length = 320
Score = 38.7 bits (86), Expect = 0.12
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 13/162 (8%)
Query: 126 VAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHL-HFRTA 184
+A +I +E Y+ L ++++Y +E K +F L + H HF
Sbjct: 1 MAEMIATEREYIRCLGYVIDNYFPEMERMDLPQGLRGKHHVIFGNLEKLHDFHQQHFLRE 60
Query: 185 LADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSALADFFK 244
L C +G FL + + +YS + A + S + FFK
Sbjct: 61 LERCQHC---PLAVGRSFLRHEEQFGMYVIYSK-----NKPQSDALLSSHGNA----FFK 108
Query: 245 VKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHA 286
KQ D++ +++PVQR ++ + LQDLLK G A
Sbjct: 109 DKQRELGDKMDLASYLLRPVQRVAKYALLLQDLLKEASCGLA 150
>AK024475-1|BAB15765.1| 1194|Homo sapiens FLJ00068 protein protein.
Length = 1194
Score = 38.7 bits (86), Expect = 0.12
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 13/160 (8%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-PAILNASKIQTLFHRLPDILQCHL 179
R + V+A ++ +E YV L+ + +Y L+ P L + LF L + H
Sbjct: 735 RLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAH-LFGNLEKLRDFHC 793
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
HF L + ++ FL V +Y+ + N + ++ S
Sbjct: 794 HF--FLRELEACTRHPPRVAYAFLR---HRVQFGMYALYSKN------KPRSDALMSSYG 842
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLK 279
FFK KQ + D L ++KP+QR ++ + LQ+L +
Sbjct: 843 HTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELAR 882
>AB197663-1|BAE07054.1| 1191|Homo sapiens puratrophin-1 protein.
Length = 1191
Score = 38.7 bits (86), Expect = 0.12
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 13/160 (8%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESS-PAILNASKIQTLFHRLPDILQCHL 179
R + V+A ++ +E YV L+ + +Y L+ P L + LF L + H
Sbjct: 732 RLQLVLAEMVATEREYVRALEYTMENYFPELDRPDVPQGLRGQRAH-LFGNLEKLRDFHC 790
Query: 180 HFRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMESKRKSAL 239
HF L + ++ FL V +Y+ + N + ++ S
Sbjct: 791 HF--FLRELEACTRHPPRVAYAFLR---HRVQFGMYALYSKN------KPRSDALMSSYG 839
Query: 240 ADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLK 279
FFK KQ + D L ++KP+QR ++ + LQ+L +
Sbjct: 840 HTFFKDKQQALGDHLDLASYLLKPIQRMGKYALLLQELAR 879
>AB018336-1|BAA34513.2| 1055|Homo sapiens KIAA0793 protein protein.
Length = 1055
Score = 38.7 bits (86), Expect = 0.12
Identities = 44/174 (25%), Positives = 76/174 (43%), Gaps = 18/174 (10%)
Query: 125 VVAAIIHSENSYVATLQRLVNDYKKPL--EESSPAILNASKIQTLFHRLPDILQCHLHF- 181
+V I+ +E +Y+ L+ + ++ + E++ PA L + LF + I + H F
Sbjct: 540 IVKEILATERTYLKDLEVITVWFRSAVVKEDAMPATL----MTLLFSNIDPIYEFHRGFL 595
Query: 182 -----RTALADC---AQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAMELAKMES 233
R AL + A T ++IG++ L + Y F + V EL K +
Sbjct: 596 REVEQRLALWEGPSKAHTKGSHQRIGDILLRNMRQLKEFTSY--FQRHDEVLTELEKA-T 652
Query: 234 KRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHTPPGHAD 287
KR L +K ++ L ++KP+QR + + L+ L H PGH D
Sbjct: 653 KRCKKLEAVYKEFELQKVCYLPLNTFLLKPIQRLLHYRLLLRRLCGHYSPGHHD 706
>AY536247-1|AAS46909.1| 137|Homo sapiens breakpoint cluster region
protein protein.
Length = 137
Score = 38.3 bits (85), Expect = 0.16
Identities = 18/59 (30%), Positives = 37/59 (62%), Gaps = 2/59 (3%)
Query: 122 RRHVVAAIIHSENSYVATLQRLVNDYK--KPLEESSPAILNASKIQTLFHRLPDILQCH 178
RR V++ I+ SE +Y++ L+ L+ K K +S +L + +I+T+F ++P++ + H
Sbjct: 19 RRWVLSGILASEETYLSHLEALLLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIH 77
>S76992-1|AAB34377.1| 878|Homo sapiens VAV2 protein.
Length = 878
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 198 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 253
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 254 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 311
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 312 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 350
>BC132967-1|AAI32968.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 193 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 248
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 249 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 306
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 307 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 345
>BC132965-1|AAI32966.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 193 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 248
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 249 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 306
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 307 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 345
>BC031573-1|AAH31573.1| 710|Homo sapiens neuronal guanine
nucleotide exchange factor protein.
Length = 710
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 71/163 (43%), Gaps = 7/163 (4%)
Query: 119 QLRRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCH 178
+++ + + ++ SE SY +L LV+ + + E IL+ S+ LF + D+L
Sbjct: 271 EIKLQEAMFELVTSEASYYKSLNLLVSHFME--NERIRKILHPSEAHILFSNVLDVLAVS 328
Query: 179 LHFRTALADCAQTWDRDEKIGEVFLSAFSKAVV-LDVYSDFINNFSVAMELAKMESKRKS 237
F L + + + I +V + A VY +++N + K + K+
Sbjct: 329 ERF---LLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKA 385
Query: 238 ALADFFKVKQISAHDR-LSFFGLMVKPVQRFPQFIMFLQDLLK 279
A + ++ R L F ++ P QR + + +Q++LK
Sbjct: 386 AFRELIAQLELDPKCRGLPFSSFLILPFQRITRLKLLVQNILK 428
>AL590710-7|CAI12279.1| 878|Homo sapiens vav 2 oncogene protein.
Length = 878
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 198 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 253
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 254 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 311
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 312 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 350
>AL590710-6|CAI12278.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 193 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 248
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 249 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 306
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 307 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 345
>AL590710-5|CAI12280.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 193 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 248
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 249 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 306
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 307 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 345
>AL445931-3|CAI13723.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 193 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 248
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 249 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 306
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 307 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 345
>AL445931-2|CAI13722.1| 878|Homo sapiens vav 2 oncogene protein.
Length = 878
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 198 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 253
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 254 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 311
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 312 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 350
>AL445931-1|CAI13724.1| 839|Homo sapiens vav 2 oncogene protein.
Length = 839
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 193 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 248
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 249 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 306
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 307 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 345
>AL357934-3|CAI15781.1| 868|Homo sapiens vav 2 oncogene protein.
Length = 868
Score = 37.9 bits (84), Expect = 0.21
Identities = 35/163 (21%), Positives = 69/163 (42%), Gaps = 12/163 (7%)
Query: 121 RRRHVVAAIIHSENSYVATLQRLVNDYKKPLEESSPAILNASKIQTLFHRLPDILQCHLH 180
+R + I +E Y TL+ + +Y PL +L+ + + +F L D+++ H
Sbjct: 193 KRNCCLLEIQETEAKYYRTLEDIEKNYMSPLR----LVLSPADMAAVFINLEDLIKVHHS 248
Query: 181 FRTALADCAQTWDRDEKIGEVFLSAFSKAVVLDVYSDFINNFSVAME--LAKMESKRKSA 238
F A+ + +VFL + ++ Y + + + LA E R+
Sbjct: 249 FLRAIDVSVMVGG--STLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKV 306
Query: 239 LADFFKVKQISAHDRLSFFGLMVKPVQRFPQFIMFLQDLLKHT 281
KV+ + L+V P+QR ++ + L++LL H+
Sbjct: 307 EECTLKVQD----GKFKLQDLLVVPMQRVLKYHLLLKELLSHS 345
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.134 0.403
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 140,770,397
Number of Sequences: 224733
Number of extensions: 5120709
Number of successful extensions: 10754
Number of sequences better than 10.0: 273
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 194
Number of HSP's that attempted gapping in prelim test: 10406
Number of HSP's gapped (non-prelim): 373
length of query: 1187
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1089
effective length of database: 51,211,004
effective search space: 55768783356
effective search space used: 55768783356
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 71 (32.7 bits)
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