GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA005346-TA|BGIBMGA005346-PA|IPR001128|Cytochrome P450
         (254 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

J04813-1|AAA02993.1|  502|Homo sapiens cytochrome P450 PCN3 prot...   180   6e-45
BC033862-1|AAH33862.1|  502|Homo sapiens cytochrome P450, family...   180   6e-45
AK223008-1|BAD96728.1|  502|Homo sapiens cytochrome P450, family...   180   6e-45
AC005020-1|AAS02016.1|  502|Homo sapiens unknown protein.             180   6e-45
D00408-1|BAA00310.1|  503|Homo sapiens cytochrome P-450 HFLa pro...   174   2e-43
BC067436-1|AAH67436.1|  503|Homo sapiens cytochrome P450, family...   174   2e-43
AF315325-1|AAG48618.1|  535|Homo sapiens cytochrome P450 variant...   174   2e-43
AF280107-3|AAG32289.1|  503|Homo sapiens cytochrome P450 polypep...   174   2e-43
M18907-1|AAA35745.1|  503|Homo sapiens protein ( Human P450 mRNA...   174   3e-43
DQ924960-1|ABI96208.1|  503|Homo sapiens cytochrome P450 family ...   174   3e-43
DQ005611-1|AAY16980.1|  503|Homo sapiens cytochrome P450, family...   174   3e-43
BC101631-1|AAI01632.1|  503|Homo sapiens cytochrome P450, subfam...   174   3e-43
BC069418-1|AAH69418.1|  503|Homo sapiens cytochrome P450, family...   174   3e-43
AJ563377-1|CAD91345.1|  353|Homo sapiens cytochrome P450 protein.     174   3e-43
AJ563376-2|CAD91645.1|  430|Homo sapiens cytochrome P450 protein.     174   3e-43
AJ563375-1|CAD91343.1|  503|Homo sapiens cytochrome P450 protein.     174   3e-43
AF280107-2|AAG32290.1|  503|Homo sapiens cytochrome P450 polypep...   174   3e-43
AF209389-1|AAF21034.1|  503|Homo sapiens cytochrome P450 IIIA4 p...   174   3e-43
M13785-1|AAA35742.1|  504|Homo sapiens protein ( Human liver glu...   173   4e-43
D00003-1|BAA00001.1|  504|Homo sapiens cytochrome P-450 protein.      173   4e-43
BC100981-1|AAI00982.1|  393|Homo sapiens CYP3A43 protein protein.     172   9e-43
AY390425-1|AAQ92353.1|  503|Homo sapiens cytochrome P450 CYP3A43...   172   9e-43
AY390424-1|AAQ92352.1|  503|Homo sapiens cytochrome P450 CYP3A43...   172   9e-43
AF337813-1|AAK38841.1|  503|Homo sapiens cytochrome P450 subfami...   172   9e-43
AF319634-1|AAK00325.1|  503|Homo sapiens cytochrome P450 CYP3A43...   172   9e-43
AF280108-1|AAG33009.1|  503|Homo sapiens cytochrome P450 subfami...   172   9e-43
AC011904-4|AAS07395.1|  503|Homo sapiens unknown protein.             172   9e-43
X12387-1|CAA30944.1|  503|Homo sapiens protein ( Human mRNA for ...   172   1e-42
M14096-1|AAA35744.1|  503|Homo sapiens protein ( Human cytochrom...   171   3e-42
J04449-1|AAA35747.1|  502|Homo sapiens cytochrome P450 nifedipin...   171   3e-42
AF182273-1|AAF13598.1|  503|Homo sapiens cytochrome P450-3A4 pro...   170   4e-42
AF280109-1|AAG33010.1|  504|Homo sapiens cytochrome P450 subfami...   168   2e-41
AC011904-5|AAS07394.1|  504|Homo sapiens unknown protein.             168   2e-41
AF233621-1|AAF99275.1|  534|Homo sapiens thromboxane synthase pr...   137   4e-32
AF233623-1|AAF99277.1|  534|Homo sapiens thromboxane synthase pr...   136   5e-32
AF233625-1|AAF99279.1|  534|Homo sapiens thromboxane synthase pr...   136   7e-32
AF233624-1|AAF99278.1|  534|Homo sapiens thromboxane synthase pr...   136   7e-32
M80647-1|AAA60618.1|  534|Homo sapiens thromboxane synthase prot...   136   9e-32
BC093896-1|AAH93896.1|  531|Homo sapiens cytochrome P450, family...   136   9e-32
BC093894-1|AAH93894.1|  531|Homo sapiens cytochrome P450, family...   136   9e-32
BC069351-1|AAH69351.1|  531|Homo sapiens cytochrome P450, family...   136   9e-32
BC041157-1|AAH41157.1|  534|Homo sapiens thromboxane A synthase ...   136   9e-32
BC014117-1|AAH14117.1|  466|Homo sapiens TBXAS1 protein protein.      136   9e-32
AK223466-1|BAD97186.1|  534|Homo sapiens thromboxane A synthase ...   136   9e-32
AK096820-1|BAC04868.1|  531|Homo sapiens protein ( Homo sapiens ...   136   9e-32
AF233622-1|AAF99276.1|  534|Homo sapiens thromboxane synthase pr...   136   9e-32
AF233620-1|AAF99274.1|  534|Homo sapiens thromboxane synthase pr...   136   9e-32
AF233619-1|AAF99273.1|  534|Homo sapiens thromboxane synthase pr...   136   9e-32
AF233618-1|AAF99272.1|  534|Homo sapiens thromboxane synthase pr...   136   9e-32
AF233617-1|AAF99271.1|  534|Homo sapiens thromboxane synthase pr...   136   9e-32
AF233616-1|AAF99270.1|  534|Homo sapiens thromboxane synthase pr...   136   9e-32
AF233615-1|AAF99269.1|  534|Homo sapiens thromboxane synthase pr...   136   9e-32
AF236085-1|AAG15889.1|  524|Homo sapiens CYP4F11 protein.             135   1e-31
BC016853-1|AAH16853.1|  524|Homo sapiens CYP4F11 protein protein.     134   2e-31
D34625-1|BAA07011.1|  533|Homo sapiens thromboxane synthase prot...   134   4e-31
BC035350-1|AAH35350.1|  524|Homo sapiens cytochrome P450, family...   134   4e-31
AC004523-1|AAC11543.1|  458|Homo sapiens F22329_1 protein.            134   4e-31
AF133298-1|AAD49566.1|  520|Homo sapiens cytochrome P450 protein.     133   7e-31
AY792513-1|AAV40834.1|  520|Homo sapiens cytochrome P450, family...   132   1e-30
AY358977-1|AAQ89336.1|  524|Homo sapiens CYP4F12 protein.             132   1e-30
AY008841-1|AAG33247.1|  524|Homo sapiens cytochrome P450 isoform...   132   1e-30
AB035131-1|BAB18270.1|  524|Homo sapiens cytochrome P450 protein.     132   1e-30
AB035130-1|BAB18269.1|  524|Homo sapiens cytochrome P450 protein.     132   1e-30
AF054821-1|AAC08589.1|  520|Homo sapiens cytochrome P-450 protein.    131   2e-30
D12620-1|BAA02144.1|  520|Homo sapiens cytochrome P-450LTBV prot...   131   3e-30
AB002461-1|BAA25991.1|  520|Homo sapiens leukotriene B4 omega-hy...   131   3e-30
AB002454-1|BAA25990.1|  520|Homo sapiens leukotriene B4 omega-hy...   131   3e-30
U02388-1|AAC50052.2|  520|Homo sapiens cytochrome P450 4F2 protein.   129   1e-29
AJ563378-3|CAD91347.1|  173|Homo sapiens hypothetical protein pr...   128   1e-29
AJ563378-2|CAD91647.1|  160|Homo sapiens cytochrome P450 protein.     128   1e-29
D26480-1|BAA05490.1|  520|Homo sapiens leukotriene B4 omega-hydr...   126   6e-29
BC067439-1|AAH67439.1|  520|Homo sapiens cytochrome P450, family...   126   6e-29
BC067437-1|AAH67437.1|  520|Homo sapiens cytochrome P450, family...   126   6e-29
AF467894-1|AAL67578.1|  520|Homo sapiens cytochrome P450, subfam...   126   6e-29
AC005336-1|AAC27730.1|  520|Homo sapiens CYP4F2 protein.              126   6e-29
BC067440-1|AAH67440.1|  520|Homo sapiens cytochrome P450, family...   126   1e-28
AB015306-1|BAA75823.1|  520|Homo sapiens Leukotriene B4 omega-hy...   126   1e-28
AY358631-1|AAQ88994.1|  505|Homo sapiens EPSW3060 protein.            119   1e-26
AY262056-1|AAO89257.1|  505|Homo sapiens cytochrome P450 protein.     119   1e-26
AL450996-2|CAH71036.1|  505|Homo sapiens cytochrome P450, family...   119   1e-26
AL135960-6|CAI19734.1|  505|Homo sapiens cytochrome P450, family...   119   1e-26
BC028102-1|AAH28102.1|  509|Homo sapiens cytochrome P450, family...   118   2e-26
AY358537-1|AAQ88901.1|  509|Homo sapiens EFSW1929 protein.            118   2e-26
AM040940-1|CAJ13826.1|  509|Homo sapiens cytochrome P450 protein.     118   2e-26
AL450996-1|CAH71035.1|  509|Homo sapiens cytochrome P450, family...   118   2e-26
AK131355-1|BAD18508.1|  508|Homo sapiens protein ( Homo sapiens ...   118   2e-26
AK098065-1|BAC05226.1|  509|Homo sapiens protein ( Homo sapiens ...   118   2e-26
AK091806-1|BAC03751.1|  444|Homo sapiens protein ( Homo sapiens ...   118   2e-26
BC060857-1|AAH60857.1|  525|Homo sapiens cytochrome P450, family...   114   2e-25
AY422002-1|AAR31180.1|  525|Homo sapiens cytochrome P450 4V2 pro...   114   2e-25
AK126473-1|BAC86562.1|  503|Homo sapiens protein ( Homo sapiens ...   114   2e-25
AK122600-1|BAC85487.1|  525|Homo sapiens protein ( Homo sapiens ...   114   2e-25
S67580-1|AAB29502.1|  519|Homo sapiens fatty acid omega-hydroxyl...   112   1e-24
AY280371-1|AAQ21367.1|  519|Homo sapiens cytochrome P450 4A22K p...   111   2e-24
AY280372-1|AAQ21368.1|  519|Homo sapiens cytochrome P450 4A22 pr...   111   2e-24
AL135960-10|CAI19737.1|  519|Homo sapiens cytochrome P450, famil...   111   2e-24
AF208532-1|AAF76722.1|  519|Homo sapiens fatty acid omega-hydrox...   111   2e-24
L04751-1|AAA58436.1|  519|Homo sapiens cytochrome P450 protein.       111   3e-24
D26481-1|BAA05491.1|  519|Homo sapiens fatty acids omega-hydroxy...   111   3e-24
AY369778-1|AAQ56847.1|  519|Homo sapiens cytochrome P450, family...   111   3e-24
AL731892-3|CAH72778.1|  519|Homo sapiens cytochrome P450, family...   111   3e-24
X16699-1|CAA34672.1|  511|Homo sapiens protein ( Human mRNA for ...   110   5e-24
J02871-1|AAA35712.1|  511|Homo sapiens protein ( Human lung cyto...   110   5e-24
DQ518907-1|ABF47106.1|  511|Homo sapiens cytochrome P450, family...   110   5e-24
BC017758-1|AAH17758.1|  512|Homo sapiens cytochrome P450, family...   110   5e-24
AY151049-1|AAN72312.1|  497|Homo sapiens pulmonary cytochrome P4...   110   5e-24
AY151048-1|AAN72311.1|  512|Homo sapiens pulmonary cytochrome P4...   110   5e-24
AY064485-1|AAL57720.1|  511|Homo sapiens cytochrome P450 protein.     110   5e-24
AL593856-7|CAI16983.1|  497|Homo sapiens cytochrome P450, family...   110   5e-24
AL593856-6|CAI16982.1|  512|Homo sapiens cytochrome P450, family...   110   5e-24
AL593856-5|CAI16981.1|  511|Homo sapiens cytochrome P450, family...   110   5e-24
AL356793-4|CAI22559.1|  511|Homo sapiens cytochrome P450, family...   110   5e-24
AL356793-3|CAI22557.1|  512|Homo sapiens cytochrome P450, family...   110   5e-24
AL356793-2|CAI22558.1|  497|Homo sapiens cytochrome P450, family...   110   5e-24
AF491285-1|AAM09532.1|  511|Homo sapiens cytochrome P450 protein.     110   5e-24
AF525488-1|AAO16078.1|  519|Homo sapiens cytochrome P450, subfam...   109   9e-24
AY064486-1|AAL57721.1|  511|Homo sapiens cytochrome P450 protein.     109   1e-23
D13705-1|BAA02864.1|  521|Homo sapiens fatty acid omega-hydroxyl...   108   2e-23
AF280110-1|AAG33011.1|  420|Homo sapiens cytochrome P450 subfami...   108   2e-23
S67581-1|AAB29503.1|  591|Homo sapiens fatty acid omega-hydroxyl...   107   4e-23
BC100982-1|AAI00983.1|  280|Homo sapiens CYP3A43 protein protein.     107   4e-23
BC022539-1|AAH22539.1|  500|Homo sapiens cytochrome P450, family...    96   9e-20
AF094480-1|AAD41244.1|  500|Homo sapiens cholesterol 24-hydroxyl...    96   9e-20
BC039307-1|AAH39307.1|  372|Homo sapiens FLJ16008 protein protein.     91   3e-18
BC032322-1|AAH32322.1|  509|Homo sapiens cytochrome P450, family...    90   6e-18
AK131190-1|BAD18388.1|  372|Homo sapiens .-.-).  protein.              90   6e-18
U23942-1|AAB39951.1|  509|Homo sapiens lanosterol 14-demethylase...    90   8e-18
D55653-1|BAA09512.1|  509|Homo sapiens lanosterol 14-demethylase...    90   8e-18
AC000120-2|AAB46356.1|  509|Homo sapiens unknown protein.              90   8e-18
X71480-1|CAA50586.1|  141|Homo sapiens cytochrome P450 protein.        89   1e-17
AK090886-1|BAC03539.1|  337|Homo sapiens protein ( Homo sapiens ...    89   1e-17
U51692-1|AAC50951.1|  503|Homo sapiens lanosterol 14-alpha demet...    87   4e-17
AL135960-11|CAI19738.1|  455|Homo sapiens cytochrome P450, famil...    86   1e-16
AL135960-9|CAI19736.1|  421|Homo sapiens cytochrome P450, family...    86   1e-16
BC041158-1|AAH41158.1|  455|Homo sapiens CYP4A11 protein protein.      86   1e-16
AL731892-4|CAH72779.1|  455|Homo sapiens cytochrome P450, family...    86   1e-16
AL358613-3|CAH72804.1|  428|Homo sapiens cytochrome P450, family...    83   1e-15
AL358613-2|CAH72803.1|  497|Homo sapiens cytochrome P450, family...    83   1e-15
AF005418-1|AAB88881.1|  497|Homo sapiens retinoic acid hydroxyla...    83   1e-15
M80646-1|AAA60617.1|  460|Homo sapiens thromboxane synthase prot...    82   2e-15
BC132767-1|AAI32768.1|  544|Homo sapiens cytochrome P450, family...    80   9e-15
AY343323-1|AAQ21380.1|  544|Homo sapiens cytochrome P450 protein.      80   9e-15
AY288916-1|AAP31972.1|  508|Homo sapiens cytochrome P450, family...    79   1e-14
AF256213-1|AAG00416.1|  508|Homo sapiens 25- hydroxyvitamin D-1-...    79   1e-14
AF246895-1|AAF64299.1|  508|Homo sapiens 25-hydroxyvitamin D-1-a...    79   1e-14
AF027152-1|AAC51854.1|  508|Homo sapiens P450 25-hydroxyvitamin ...    79   1e-14
AF020192-1|AAC51853.1|  508|Homo sapiens 25-hydroxyvitamin D-1-a...    79   1e-14
AB006987-1|BAA23418.1|  508|Homo sapiens 25-hydroxyvitamin D3 1-...    79   1e-14
AB005990-1|BAA22657.1|  508|Homo sapiens 25-hydroxyvitamin D3 1a...    79   1e-14
AB005989-1|BAA22656.1|  508|Homo sapiens 25-hydroxyvitamin D3 1a...    79   1e-14
AB005038-1|BAA23416.1|  508|Homo sapiens 25-hydroxyvitamin D3 1-...    79   1e-14
Y07508-1|CAA68807.1|  503|Homo sapiens protein ( Human mRNA for ...    78   3e-14
X13589-1|CAA31929.1|  503|Homo sapiens protein ( Human mRNA for ...    78   3e-14
M30804-1|AAA35728.1|  503|Homo sapiens protein ( Human aromatase...    78   3e-14
M22246-1|AAA35557.1|  503|Homo sapiens protein ( Human aromatase...    78   3e-14
M18856-1|AAA35556.1|  419|Homo sapiens protein ( Human aromatase...    78   3e-14
DQ118405-1|AAZ23558.1|  503|Homo sapiens cytochrome P450 subfami...    78   3e-14
BC107785-1|AAI07786.1|  503|Homo sapiens cytochrome P450, family...    78   3e-14
BC035959-1|AAH35959.1|  503|Homo sapiens cytochrome P450, family...    78   3e-14
AY957953-1|AAX44046.1|  503|Homo sapiens cytochrome P450, family...    78   3e-14
S67623-1|AAB29308.1|  257|Homo sapiens 25-hydroxyvitamin D 24-hy...    78   3e-14
L13286-1|AAA62379.1|  513|Homo sapiens 1,25-dihydroxyvitamin D3 ...    78   3e-14
AY858838-1|AAW50795.1|  372|Homo sapiens vitamin D 24-hydroxylas...    78   3e-14
AL138805-3|CAB91829.1|  514|Homo sapiens cytochrome P450, family...    78   3e-14
AL138805-1|CAM27342.1|  372|Homo sapiens cytochrome P450, family...    78   3e-14
X54741-1|CAA38539.1|  503|Homo sapiens aldosterone  synthase (P-...    77   5e-14
D13752-1|BAA02899.1|  503|Homo sapiens steroid 18-hydroxylase pr...    77   5e-14
M32881-1|AAA35741.1|  503|Homo sapiens protein ( Human steroid 1...    77   6e-14
M28420-1|AAA52141.1|  419|Homo sapiens cytochrome P-450 aromatas...    77   8e-14
J04127-1|AAA52132.1|  503|Homo sapiens CYP19 protein.                  77   8e-14
AM183950-1|CAJ75804.1|  494|Homo sapiens steroid 21-hydroxylase,...    77   8e-14
X59812-1|CAA42481.1|  530|Homo sapiens Vitamin D3 25-hydroxylase...    76   1e-13
M62401-1|AAA52142.1|  531|Homo sapiens sterol 27-hydroxylase pro...    76   1e-13
M26856-1|AAA52064.1|  495|Homo sapiens protein ( Human 21-hydrox...    76   1e-13
M13936-1|AAA59695.1|  494|Homo sapiens CYP21P protein.                 76   1e-13
BX679671-8|CAM26071.1|  464|Homo sapiens cytochrome P450, family...    76   1e-13
BX679671-7|CAM26070.1|  494|Homo sapiens cytochrome P450, family...    76   1e-13
BC125182-1|AAI25183.1|  494|Homo sapiens cytochrome P450, family...    76   1e-13
BC125181-1|AAI25182.1|  495|Homo sapiens cytochrome P450, family...    76   1e-13
BC051851-1|AAH51851.1|  531|Homo sapiens cytochrome P450, family...    76   1e-13
BC040430-1|AAH40430.1|  531|Homo sapiens cytochrome P450, family...    76   1e-13
AM183951-1|CAJ75805.1|  494|Homo sapiens steroid 21-hydroxylase,...    76   1e-13
AM183947-1|CAJ75801.1|  494|Homo sapiens steroid 21-hydroxylase,...    76   1e-13
AM183946-1|CAJ75800.1|  494|Homo sapiens steroid 21-hydroxylase,...    76   1e-13
AM183945-1|CAJ75799.1|  494|Homo sapiens steroid 21-hydroxylase,...    76   1e-13
AM086565-1|CAJ31104.1|  494|Homo sapiens steroid 21-hydroxylase,...    76   1e-13
AM086564-1|CAJ31103.1|  494|Homo sapiens steroid 21-hydroxylase,...    76   1e-13
AL929593-2|CAI41778.1|  465|Homo sapiens cytochrome P450, family...    76   1e-13
AL929593-1|CAI41779.1|  495|Homo sapiens cytochrome P450, family...    76   1e-13
AL662849-19|CAI17480.1|  465|Homo sapiens cytochrome P450, famil...    76   1e-13
AL662849-18|CAI17479.1|  495|Homo sapiens cytochrome P450, famil...    76   1e-13
AL645922-24|CAI41754.1|  495|Homo sapiens cytochrome P450, famil...    76   1e-13
AL645922-23|CAI41755.1|  465|Homo sapiens cytochrome P450, famil...    76   1e-13
AL049547-7|CAB89301.1|  495|Homo sapiens dJ34F7.3 (cytochrome P4...    76   1e-13
AF077974-1|AAD45405.1|  403|Homo sapiens cytochrome P450 21-hydr...    76   1e-13
AF019413-2|AAB67982.1|  495|Homo sapiens cytochrome P450 21-hydr...    76   1e-13
X58906-1|CAA41709.1|  495|Homo sapiens steroid 21-monooxygenase ...    76   1e-13
M28548-1|AAA52065.1|  495|Homo sapiens protein ( Human mutant 21...    76   1e-13
M21550-1|AAA52063.1|  495|Homo sapiens CYP21 protein.                  76   1e-13
AM183949-1|CAJ75803.1|  494|Homo sapiens steroid 21-hydroxylase,...    76   1e-13
AK054616-1|BAB70774.1|  465|Homo sapiens protein ( Homo sapiens ...    75   2e-13
AY178622-1|AAO21126.1|  531|Homo sapiens steroid hydroxylase pro...    75   2e-13
AM183948-1|CAJ75802.1|  494|Homo sapiens steroid 21-hydroxylase ...    74   4e-13
M32879-1|AAA52149.1|  503|Homo sapiens CYP11B1 protein.                74   6e-13
BC096287-1|AAH96287.1|  503|Homo sapiens cytochrome P450, family...    74   6e-13
BC096285-1|AAH96285.1|  574|Homo sapiens CYP11B1 protein protein.      74   6e-13
AF478474-1|AAL84813.1|  503|Homo sapiens mutated cytochrome P-45...    74   6e-13
X55764-1|CAA39290.1|  503|Homo sapiens protein ( Human mRNA for ...    73   7e-13
M12792-1|AAB59440.1|  494|Homo sapiens steroid 21-hydroxylase pr...    73   7e-13
BC067433-1|AAH67433.1|  493|Homo sapiens cytochrome P450, family...    72   2e-12
J02843-1|AAA52155.1|  493|Homo sapiens protein ( Human cytochrom...    72   2e-12
J02625-1|AAA35743.1|  493|Homo sapiens protein ( Human cytochrom...    72   2e-12
DQ515958-1|ABF47105.1|  493|Homo sapiens cytochrome P450, family...    72   2e-12
DQ149222-1|AAZ77710.1|  493|Homo sapiens cytochrome P450 2E1 pro...    72   2e-12
AL161645-2|CAH70047.1|  493|Homo sapiens cytochrome P450, family...    72   2e-12
AF182276-1|AAF13601.1|  493|Homo sapiens cytochrome P450-2E1 pro...    72   2e-12
AF084225-1|AAD13753.1|  462|Homo sapiens cytochrome P450 2E1 pro...    72   2e-12
BC104909-1|AAI04910.1|  501|Homo sapiens cytochrome P450, family...    71   4e-12
BC104907-1|AAI04908.1|  501|Homo sapiens cytochrome P450, family...    71   4e-12
BC067435-1|AAH67435.1|  493|Homo sapiens cytochrome P450, family...    71   4e-12
AY323817-1|AAQ23114.1|  501|Homo sapiens cytochrome P450 2R1 pro...    71   4e-12
AJ563379-2|CAD91649.1|   84|Homo sapiens cytochrome P450 protein.      70   9e-12
X65962-1|CAA46778.1|  356|Homo sapiens cytochrome P-450 II C pro...    69   1e-11
M17252-1|AAA59985.1|  230|Homo sapiens CYP21 protein.                  69   1e-11
U37143-1|AAC50370.2|  502|Homo sapiens cytochrome P450 monooxyge...    69   2e-11
BC032594-1|AAH32594.1|  502|Homo sapiens cytochrome P450, family...    69   2e-11
AY426985-1|AAQ93356.1|  502|Homo sapiens cytochrome P450, family...    69   2e-11
AF272142-1|AAM44456.1|  502|Homo sapiens cytochrome P450 protein.      69   2e-11
BC109205-1|AAI09206.1|  512|Homo sapiens cytochrome P450, family...    68   3e-11
BC069443-1|AAH69443.1|  512|Homo sapiens cytochrome P450, family...    68   3e-11
AF252297-1|AAF76003.1|  512|Homo sapiens cytochrome P450 retinoi...    68   3e-11
AC007002-1|AAY14690.1|  512|Homo sapiens unknown protein.              68   3e-11
M24667-1|AAA52148.1|  256|Homo sapiens steroid 11-beta-hydroxyla...    68   4e-11
L36085-1|AAC01761.1|  441|Homo sapiens thromboxane A2 synthase p...    68   4e-11
BC067429-1|AAH67429.1|  516|Homo sapiens cytochrome P450, family...    67   5e-11
AB080265-1|BAB85489.1|  502|Homo sapiens cytochrome P450 2J2 pro...    67   6e-11
L07093-1|AAA36660.1|  468|Homo sapiens cytochrome P450 protein.        65   2e-10
BC096256-1|AAH96256.1|  494|Homo sapiens cytochrome P450, family...    65   2e-10
AY796203-1|AAV41877.1|  490|Homo sapiens cytochrome P450, family...    65   2e-10
AL583836-2|CAH74068.1|  490|Homo sapiens cytochrome P450, family...    65   2e-10
AL133513-2|CAH73444.1|  490|Homo sapiens cytochrome P450, family...    65   2e-10
Z00036-1|CAA77335.1|  515|Homo sapiens protein ( Human mRNA for ...    65   3e-10
M61854-1|AAB59426.1|  490|Homo sapiens cytochrome protein.             65   3e-10
M55053-1|AAA52146.1|  515|Homo sapiens cytochrome P3-450 protein.      65   3e-10
M31667-1|AAA52163.1|  515|Homo sapiens CYP1A2 protein.                 65   3e-10
L00389-1|AAA35738.1|  516|Homo sapiens protein ( Human cytochrom...    65   3e-10
DQ022432-1|AAY26399.1|  516|Homo sapiens cytochrome P450, family...    65   3e-10
BC117165-1|AAI17166.1|  494|Homo sapiens cytochrome P450, family...    65   3e-10
BC067428-1|AAH67428.1|  516|Homo sapiens cytochrome P450, family...    65   3e-10
BC067427-1|AAH67427.1|  516|Homo sapiens cytochrome P450, family...    65   3e-10
BC067426-1|AAH67426.1|  516|Homo sapiens cytochrome P450, family...    65   3e-10
BC067425-1|AAH67425.1|  516|Homo sapiens cytochrome P450, family...    65   3e-10
BC067424-1|AAH67424.1|  516|Homo sapiens cytochrome P450, family...    65   3e-10
AF253322-2|AAK25728.1|  516|Homo sapiens cytochrome P450 protein.      65   3e-10
AF182274-1|AAF13599.1|  516|Homo sapiens cytochrome P450-1A2 pro...    65   3e-10
AF182275-1|AAF13600.1|  494|Homo sapiens cytochrome P450-2A6 pro...    64   3e-10
X13930-1|CAA32118.1|  494|Homo sapiens protein ( Human CYP2A4 mR...    64   5e-10
X13929-1|CAA32117.1|  448|Homo sapiens P-450 IIA3 protein (1 is ...    64   5e-10
X13897-1|CAA32097.1|  489|Homo sapiens protein ( Human mRNA for ...    64   5e-10
M33318-1|AAA52067.1|  494|Homo sapiens CYP2A protein.                  64   5e-10
BC096255-1|AAH96255.1|  494|Homo sapiens cytochrome P450, family...    64   5e-10
BC096254-1|AAH96254.1|  494|Homo sapiens cytochrome P450, family...    64   5e-10
BC096253-1|AAH96253.3|  494|Homo sapiens cytochrome P450, family...    64   5e-10
M33317-1|AAA52138.1|  494|Homo sapiens CYP2A protein.                  64   6e-10
M63871-1|AAA59984.1|  508|Homo sapiens CYP17 protein.                  63   1e-09
M31153-1|AAA52140.1|  508|Homo sapiens CYP17 protein.                  63   1e-09
M19489-1|AAA36405.1|  508|Homo sapiens CYP17 protein.                  63   1e-09
M14564-1|AAA52151.1|  508|Homo sapiens CYP17 protein.                  63   1e-09
DQ530598-1|ABF50972.1|  508|Homo sapiens cytochrome P450, family...    63   1e-09
BT020000-1|AAV38803.1|  508|Homo sapiens cytochrome P450, family...    63   1e-09
BC063388-1|AAH63388.1|  508|Homo sapiens cytochrome P450, family...    63   1e-09
BC062997-1|AAH62997.1|  508|Homo sapiens cytochrome P450, family...    63   1e-09
AY513609-1|AAR90940.1|  494|Homo sapiens cytochrome P450 2A13 va...    63   1e-09
AL358790-3|CAI52498.1|  508|Homo sapiens cytochrome P450, family...    63   1e-09
L39102-1|AAL31348.1|  217|Homo sapiens S-mephenytoin 4-hydroxyla...    62   1e-09
DQ680079-1|ABG25922.1|  347|Homo sapiens truncated cytochrome P4...    62   2e-09
M61858-1|AAA52145.1|  370|Homo sapiens CYP2C17 protein.                62   2e-09
AY513608-1|AAR90939.1|  494|Homo sapiens cytochrome P450 2A13 va...    62   2e-09
AY513606-1|AAR90937.1|  494|Homo sapiens cytochrome P450 2A13 va...    62   2e-09
AY513605-1|AAR90936.1|  494|Homo sapiens cytochrome P450 2A13 va...    62   2e-09
AY513604-1|AAR90935.1|  494|Homo sapiens cytochrome P450 2A13 va...    62   2e-09
AF209774-1|AAG35775.1|  494|Homo sapiens cytochrome P450 2A13 pr...    62   2e-09
X05367-1|CAA28965.1|  521|Homo sapiens desmolase protein.              61   3e-09
M28253-1|AAA36404.1|  239|Homo sapiens cytochrome P-450-scc prot...    61   3e-09
M21939-1|AAA52158.1|  485|Homo sapiens CYP2C protein.                  61   3e-09
M15331-1|AAA52157.1|  485|Homo sapiens CYP2C protein.                  61   3e-09
M14565-1|AAA52162.1|  521|Homo sapiens CYP11A protein.                 61   3e-09
BC032329-1|AAH32329.1|  521|Homo sapiens cytochrome P450, family...    61   3e-09
S46963-1|AAB23864.2|  477|Homo sapiens cytochrome P-450 protein.       61   4e-09
M21940-1|AAA52159.1|  383|Homo sapiens CYP2C protein.                  61   4e-09
M12078-1|AAA52154.1|  192|Homo sapiens POR protein.                    61   4e-09
D00173-1|BAA00123.1|  487|Homo sapiens cytochrome P-450 protein.       61   4e-09
BC125054-1|AAI25055.1|  490|Homo sapiens cytochrome P450, family...    61   4e-09
AY702706-1|AAT94065.1|  490|Homo sapiens cytochrome P450, family...    61   4e-09
AY341248-1|AAP88931.1|  490|Homo sapiens cytochrome P450, family...    61   4e-09
AL359672-1|CAH71303.1|  490|Homo sapiens cytochrome P450, family...    61   4e-09
DQ282153-1|ABB77901.1|  497|Homo sapiens cytochrome P450 2D6 pro...    60   6e-09
K03192-1|AAA52147.1|  331|Homo sapiens CYP1A1 protein.                 60   7e-09
BC106758-1|AAI06759.1|  497|Homo sapiens cytochrome P450, family...    60   7e-09
DQ211353-1|ABB01370.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   1e-08
M33388-1|AAA53500.1|  497|Homo sapiens cytochrome P450 IID6 prot...    59   2e-08
M33189-1|AAA35737.1|  500|Homo sapiens protein ( Human debrisoqu...    59   2e-08
M24499-1|AAA36403.1|  373|Homo sapiens cytochrome P450db1 protein.     59   2e-08
DQ282162-1|ABB77909.1|  500|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282160-1|ABB77908.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282159-1|ABB77907.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282158-1|ABB77906.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282157-1|ABB77905.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282156-1|ABB77904.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282155-1|ABB77903.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282154-1|ABB77902.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282152-1|ABB77900.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282151-1|ABB77899.1|  496|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282147-1|ABB77898.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282146-1|ABB77897.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282145-1|ABB77896.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ282144-1|ABB77895.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ211354-2|ABB01372.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
DQ211353-2|ABB01371.1|  497|Homo sapiens cytochrome P450 2D6 pro...    59   2e-08
CR456430-1|CAG30316.1|  446|Homo sapiens CYP2D6 protein.               59   2e-08
BC126858-1|AAI26859.1|  497|Homo sapiens cytochrome P450, family...    59   2e-08
BC106757-1|AAI06758.1|  446|Homo sapiens cytochrome P450, family...    59   2e-08
BC075024-1|AAH75024.1|  497|Homo sapiens cytochrome P450, family...    59   2e-08
BC075023-1|AAH75023.1|  497|Homo sapiens cytochrome P450, family...    59   2e-08
BC067432-1|AAH67432.1|  497|Homo sapiens cytochrome P450, family...    59   2e-08
BC066877-1|AAH66877.1|  446|Homo sapiens CYP2D6 protein protein.       59   2e-08
AY545216-1|AAS55001.1|  497|Homo sapiens cytochrome P4502D6 prot...    59   2e-08
AK223510-1|BAD97230.1|  490|Homo sapiens cytochrome P450, family...    59   2e-08
AB209492-1|BAD92729.1|  566|Homo sapiens Debrisoquine 4-hydroxyl...    59   2e-08
M61856-1|AAB59356.1|  490|Homo sapiens cytochrome protein.             58   2e-08
BX538127-1|CAD98029.1|  310|Homo sapiens hypothetical protein pr...    58   2e-08
BC096260-1|AAH96260.1|  431|Homo sapiens CYP2C18 protein protein.      58   2e-08
BC096258-1|AAH96258.1|  490|Homo sapiens cytochrome P450, family...    58   2e-08
BC096257-1|AAH96257.1|  490|Homo sapiens cytochrome P450, family...    58   2e-08
BC069666-1|AAH69666.1|  490|Homo sapiens cytochrome P450, family...    58   2e-08
BC033691-1|AAH33691.1|  504|Homo sapiens cytochrome P450, family...    58   2e-08
AY358603-1|AAQ88966.1|  504|Homo sapiens Cytochrome p450 protein.      58   2e-08
AL583836-1|CAH74067.1|  490|Homo sapiens cytochrome P450, family...    58   2e-08
AK027605-1|BAB55227.1|  564|Homo sapiens protein ( Homo sapiens ...    58   2e-08
AF335278-1|AAK13498.1|  504|Homo sapiens cytochrome P450 2S1 pro...    58   2e-08
AB209700-1|BAD92937.1|  336|Homo sapiens cytochrome P450, family...    58   3e-08
X08006-1|CAA30807.1|  497|Homo sapiens cytochrome P450 db1 protein.    58   4e-08
U22028-1|AAB40519.1|  494|Homo sapiens cytochrome P450 protein.        58   4e-08
M20403-1|AAA52153.1|  497|Homo sapiens CYP2D protein.                  58   4e-08
X04300-1|CAA27843.1|  512|Homo sapiens P-450 c protein.                57   5e-08
X02612-1|CAA26458.1|  512|Homo sapiens cytochrome P(1)-450 protein.    57   5e-08
U22029-1|AAB40520.1|  494|Homo sapiens cytochrome P450 protein.        57   5e-08
J02906-1|AAA52156.1|  491|Homo sapiens CYP2F1 protein.                 57   5e-08
EF094025-1|ABK41999.1|  512|Homo sapiens cytochrome P450, family...    57   5e-08
BC023019-1|AAH23019.1|  512|Homo sapiens cytochrome P450, family...    57   5e-08
AY310359-1|AAQ76692.1|  484|Homo sapiens cytochrome P450 1A1 var...    57   5e-08
AM236047-1|CAJ84704.1|  251|Homo sapiens cytochrome P450 1A1 pro...    57   5e-08
AK223113-1|BAD96833.1|  512|Homo sapiens cytochrome P450, family...    57   5e-08
AF253322-1|AAK25727.1|  512|Homo sapiens cytochrome P450 protein.      57   5e-08
Y00498-1|CAA68550.1|  490|Homo sapiens IIC2 protein.                   57   7e-08
M21942-1|AAA52161.1|  462|Homo sapiens CYP2C protein.                  57   7e-08
M17397-1|AAA35739.1|  490|Homo sapiens protein ( Human cytochrom...    57   7e-08
M12079-1|AAA52152.1|  191|Homo sapiens POR protein.                    57   7e-08
K03191-1|AAA52139.1|  512|Homo sapiens CYP1A1 protein.                 57   7e-08
BC020596-1|AAH20596.1|  490|Homo sapiens cytochrome P450, family...    57   7e-08
AY514490-1|AAR89907.1|  490|Homo sapiens cytochrome P450, family...    57   7e-08
AL359672-5|CAH71307.1|  490|Homo sapiens cytochrome P450, family...    57   7e-08
U22027-1|AAB40518.1|  494|Homo sapiens cytochrome P450 protein.        56   9e-08
M21941-1|AAA52160.1|  480|Homo sapiens CYP2C protein.                  56   1e-07
L16876-1|AAA02630.1|  490|Homo sapiens cytochrome P-4502C18 prot...    56   1e-07
AF372573-1|AAL69652.1|  495|Homo sapiens cytochrome P450 2F1 pro...    56   1e-07
AK223108-1|BAD96828.1|  512|Homo sapiens cytochrome P450, family...    55   2e-07
AL358613-1|CAH72802.2|  522|Homo sapiens cytochrome P450, family...    55   3e-07
AY356349-1|AAQ55485.1|  522|Homo sapiens cytochrome P450 protein.      54   4e-07
X51535-1|CAA35915.1|  210|Homo sapiens cytochrome P-450 HPH (120...    54   6e-07
BC025761-1|AAH25761.2|  490|Homo sapiens cytochrome P450, family...    53   1e-06
D12621-1|BAA02145.1|  389|Homo sapiens cytochrome P-450LTBV prot...    52   1e-06
AF176805-1|AAK11850.1|  506|Homo sapiens oxysterol 7alpha-hydrox...    51   3e-06
AF127090-1|AAD20021.1|  506|Homo sapiens oxysterol 7alpha-hydrox...    51   3e-06
AF029403-1|AAC95426.1|  506|Homo sapiens oxysterol 7alpha-hydrox...    51   3e-06
M29874-1|AAA52144.1|  491|Homo sapiens CYP2B protein.                  50   1e-05
DQ298753-1|ABB84469.1|  491|Homo sapiens cytochrome P450, family...    50   1e-05
BC067431-1|AAH67431.1|  491|Homo sapiens cytochrome P450, family...    50   1e-05
BC067430-1|AAH67430.1|  491|Homo sapiens cytochrome P450, family...    50   1e-05
AF182277-1|AAF13602.1|  491|Homo sapiens cytochrome P450-2B6 pro...    50   1e-05
AC023172-1|AAF32444.1|  491|Homo sapiens CYP2B6 protein.               50   1e-05
AY359068-1|AAQ89427.1|  462|Homo sapiens P450-like protein protein.    49   2e-05
BC029155-1|AAH29155.1|  489|Homo sapiens Unknown (protein for IM...    48   2e-05
BC093022-1|AAH93022.1|  416|Homo sapiens CYP20A1 protein protein.      48   3e-05
BC033752-1|AAH33752.1|  462|Homo sapiens cytochrome P450, family...    48   3e-05
BC020616-1|AAH20616.1|  462|Homo sapiens cytochrome P450, family...    48   3e-05
M93133-1|AAA58435.1|  504|Homo sapiens cholesterol 7-alpha hydro...    48   4e-05
BC128535-1|AAI28536.1|  143|Homo sapiens LOC283480 protein protein.    48   4e-05
BC112184-1|AAI12185.1|  504|Homo sapiens cytochrome P450, family...    48   4e-05
BC101777-1|AAI01778.1|  504|Homo sapiens cytochrome P450, family...    48   4e-05
AC004914-2|AAP21887.1|  311|Homo sapiens unknown protein.              47   7e-05
AC004914-1|AAD21788.1|  348|Homo sapiens unknown protein.              47   7e-05
L16883-1|AAD13467.1|  169|Homo sapiens cytochrome P-450 2C protein.    46   1e-04
AY220845-1|AAO49806.1|  516|Homo sapiens cytochrome P450 protein.      46   1e-04
U03688-1|AAA19567.1|  543|Homo sapiens cytochrome P450 protein.        46   1e-04
BT020001-1|AAV38804.1|  543|Homo sapiens cytochrome P450, family...    46   1e-04
BC012049-1|AAH12049.1|  543|Homo sapiens cytochrome P450, family...    46   1e-04
AF183412-1|AAG09681.1|  435|Homo sapiens cytochrome P450 monooxy...    46   1e-04
AC009229-2|AAY15039.1|  543|Homo sapiens unknown protein.              46   1e-04
U56438-1|AAC50809.1|  543|Homo sapiens dioxin-inducible cytochro...    46   2e-04
BT019979-1|AAV38782.1|  543|Homo sapiens cytochrome P450, family...    46   2e-04
BC067444-1|AAH67444.1|  501|Homo sapiens cytochrome P450, family...    46   2e-04
BC067442-1|AAH67442.1|  501|Homo sapiens cytochrome P450, family...    46   2e-04
AY393998-1|AAQ87875.1|  543|Homo sapiens cytochrome P450, family...    46   2e-04
AF450132-1|AAM50512.1|  543|Homo sapiens cytochrome P450 CYP1B1 ...    46   2e-04
AF237982-1|AAF63329.1|  469|Homo sapiens oxysterol 7alpha-hydrox...    46   2e-04
AF090320-1|AAD19877.1|  501|Homo sapiens sterol 12-alpha-hydroxy...    46   2e-04
AF090318-1|AAC63037.1|  462|Homo sapiens sterol 12-alpha hydroxy...    46   2e-04
AL591242-1|CAH73899.1|  469|Homo sapiens cytochrome P450, family...    45   2e-04
AL035670-1|CAI20276.1|  469|Homo sapiens cytochrome P450, family...    45   2e-04
BC067441-1|AAH67441.1|  501|Homo sapiens cytochrome P450, family...    45   3e-04
BC067434-1|AAH67434.1|  501|Homo sapiens cytochrome P450, family...    45   3e-04
AK127151-1|BAC86855.1|  146|Homo sapiens protein ( Homo sapiens ...    45   3e-04
X56088-1|CAA39568.1|  504|Homo sapiens cholesterol  7-alpha-hydr...    44   4e-04
BC010358-1|AAH10358.1|  469|Homo sapiens cytochrome P450, family...    44   4e-04
BC096259-1|AAH96259.1|  443|Homo sapiens CYP2C18 protein protein.      44   5e-04
AF297052-1|AAG31785.1|  500|Homo sapiens prostacyclin synthase p...    44   5e-04
D84124-1|BAA28219.1|  509|Homo sapiens prostacyclin synthase pro...    44   7e-04
D83402-1|BAA11910.1|  500|Homo sapiens prostacyclin synthase pro...    44   7e-04
D38145-1|BAA07343.1|  500|Homo sapiens prostacyclin synthase pro...    44   7e-04
BC101811-1|AAI01812.1|  500|Homo sapiens prostaglandin I2 (prost...    44   7e-04
BC101809-1|AAI01810.1|  500|Homo sapiens prostaglandin I2 (prost...    44   7e-04
AL118525-1|CAC14162.1|  500|Homo sapiens prostaglandin I2 (prost...    44   7e-04
AF297051-1|AAG31784.1|  500|Homo sapiens prostacyclin synthase p...    44   7e-04
AF297050-1|AAG31783.1|  500|Homo sapiens prostacyclin synthase p...    44   7e-04
AF297049-1|AAG31782.1|  500|Homo sapiens prostacyclin synthase p...    44   7e-04
AF297048-1|AAG31781.1|  500|Homo sapiens prostacyclin synthase p...    44   7e-04
AJ877238-1|CAI47002.1|   97|Homo sapiens putative cytochrome P45...    42   0.002
AM233517-1|CAJ80720.1|  175|Homo sapiens cytochrome P450 1A1 pro...    42   0.002
AC005336-2|AAC27731.1|   93|Homo sapiens F20191_1, partial CDS p...    42   0.002
BC096286-1|AAH96286.1|  437|Homo sapiens cytochrome P450, family...    41   0.004
AK000366-1|BAA91114.1|  408|Homo sapiens protein ( Homo sapiens ...    40   0.006
S77409-1|AAB34643.1|  228|Homo sapiens steroid 18-hydroxylase pr...    40   0.011
X58904-1|CAA41707.1|  371|Homo sapiens steroid 21-monooxygenase ...    39   0.020
X58902-1|CAA41706.1|  372|Homo sapiens steroid 21-monooxygenase ...    39   0.020
X58900-1|CAA41704.1|  372|Homo sapiens steroid 21-monooxygenase ...    39   0.020
X58899-1|CAA41703.1|  368|Homo sapiens steroid 21-monooxygenase ...    39   0.020
X58898-1|CAA41702.1|  371|Homo sapiens steroid 21-monooxygenase ...    39   0.020
AK127234-1|BAC86895.1|  130|Homo sapiens ).  protein.                  38   0.045
AF144566-1|AAD30164.1|  339|Homo sapiens cytochrome P450 epoxyge...    38   0.045
DQ016495-1|AAY34975.1|  195|Homo sapiens cytochrome P450 1B1 pro...    36   0.10 
AK094090-1|BAC04283.1|  153|Homo sapiens protein ( Homo sapiens ...    34   0.42 
AY871801-1|AAX62803.1|  483|Homo sapiens cytochrome P450 family ...    33   0.97 
AM233518-1|CAJ80721.1|  157|Homo sapiens cytochrome P450 1A1 pro...    33   1.3  
AF040259-1|AAD10199.1|  144|Homo sapiens cytochrome P450 1A1 pro...    33   1.3  
AK131339-1|BAD18496.1|  300|Homo sapiens protein ( Homo sapiens ...    30   6.8  
D50111-1|BAA08796.1|   46|Homo sapiens CYP2EI protein.                 30   9.1  
BC021259-1|AAH21259.2|  517|Homo sapiens tripartite motif-contai...    30   9.1  

>J04813-1|AAA02993.1|  502|Homo sapiens cytochrome P450 PCN3
           protein.
          Length = 502

 Score =  180 bits (437), Expect = 6e-45
 Identities = 93/249 (37%), Positives = 150/249 (60%), Gaps = 12/249 (4%)

Query: 6   KAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSST 65
           K+     +  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S+
Sbjct: 258 KSRLNDKQKHRLDFLQLMIDSQNSKETESHKA-----LSDLELAAQSIIFIFAGYETTSS 312

Query: 66  LLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVAR 124
           +LSF ++ LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R
Sbjct: 313 VLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIR 372

Query: 125 VDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR-PS 183
           ++R C K   I G  V +  G  V IP Y LH D   + E  EF+PERF   +KKD    
Sbjct: 373 LERTCKKDVEING--VFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF--SKKKDSIDP 428

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKG 243
           ++Y PFG GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+  D +  LL+  K 
Sbjct: 429 YIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG-LLQPEKP 487

Query: 244 LWVRIELID 252
           + ++++  D
Sbjct: 488 IVLKVDSRD 496


>BC033862-1|AAH33862.1|  502|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 5 protein.
          Length = 502

 Score =  180 bits (437), Expect = 6e-45
 Identities = 93/249 (37%), Positives = 150/249 (60%), Gaps = 12/249 (4%)

Query: 6   KAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSST 65
           K+     +  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S+
Sbjct: 258 KSRLNDKQKHRLDFLQLMIDSQNSKETESHKA-----LSDLELAAQSIIFIFAGYETTSS 312

Query: 66  LLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVAR 124
           +LSF ++ LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R
Sbjct: 313 VLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIR 372

Query: 125 VDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR-PS 183
           ++R C K   I G  V +  G  V IP Y LH D   + E  EF+PERF   +KKD    
Sbjct: 373 LERTCKKDVEING--VFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF--SKKKDSIDP 428

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKG 243
           ++Y PFG GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+  D +  LL+  K 
Sbjct: 429 YIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG-LLQPEKP 487

Query: 244 LWVRIELID 252
           + ++++  D
Sbjct: 488 IVLKVDSRD 496


>AK223008-1|BAD96728.1|  502|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 5 variant protein.
          Length = 502

 Score =  180 bits (437), Expect = 6e-45
 Identities = 93/249 (37%), Positives = 150/249 (60%), Gaps = 12/249 (4%)

Query: 6   KAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSST 65
           K+     +  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S+
Sbjct: 258 KSRLNDKQKHRLDFLQLMIDSQNSKETESHKA-----LSDLELAAQSIIFIFAGYETTSS 312

Query: 66  LLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVAR 124
           +LSF ++ LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R
Sbjct: 313 VLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIR 372

Query: 125 VDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR-PS 183
           ++R C K   I G  V +  G  V IP Y LH D   + E  EF+PERF   +KKD    
Sbjct: 373 LERTCMKDVEING--VFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF--SKKKDSIDP 428

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKG 243
           ++Y PFG GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+  D +  LL+  K 
Sbjct: 429 YIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG-LLQPEKP 487

Query: 244 LWVRIELID 252
           + ++++  D
Sbjct: 488 IVLKVDSRD 496


>AC005020-1|AAS02016.1|  502|Homo sapiens unknown protein.
          Length = 502

 Score =  180 bits (437), Expect = 6e-45
 Identities = 93/249 (37%), Positives = 150/249 (60%), Gaps = 12/249 (4%)

Query: 6   KAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSST 65
           K+     +  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S+
Sbjct: 258 KSRLNDKQKHRLDFLQLMIDSQNSKETESHKA-----LSDLELAAQSIIFIFAGYETTSS 312

Query: 66  LLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVAR 124
           +LSF ++ LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R
Sbjct: 313 VLSFTLYELATHPDVQQKLQKEIDAVLPNKAPPTYDAVVQMEYLDMVVNETLRLFPVAIR 372

Query: 125 VDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR-PS 183
           ++R C K   I G  V +  G  V IP Y LH D   + E  EF+PERF   +KKD    
Sbjct: 373 LERTCKKDVEING--VFIPKGSMVVIPTYALHHDPKYWTEPEEFRPERF--SKKKDSIDP 428

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKG 243
           ++Y PFG GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+  D +  LL+  K 
Sbjct: 429 YIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG-LLQPEKP 487

Query: 244 LWVRIELID 252
           + ++++  D
Sbjct: 488 IVLKVDSRD 496


>D00408-1|BAA00310.1|  503|Homo sapiens cytochrome P-450 HFLa
           protein.
          Length = 503

 Score =  174 bits (424), Expect = 2e-43
 Identities = 88/237 (37%), Positives = 145/237 (61%), Gaps = 8/237 (3%)

Query: 3   QAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYET 62
           Q  +   + ++  + DFLQ++ID  ++ +  ++T K    L D  + AQS++F+ AGYET
Sbjct: 255 QIKEGRLKETQKHRVDFLQLMID--SQNSKDSETHKA---LSDLELMAQSIIFIFAGYET 309

Query: 63  SSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPP 121
           +S++LSF I+ LAT PD+Q+ ++  +  +   K   +Y+ + Q++YL+  + ETLR++P 
Sbjct: 310 TSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPV 369

Query: 122 VARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
             R++R+C K   I G  +  GV   V IP Y LH D   + E  +F PERF    K + 
Sbjct: 370 AMRLERVCKKDVEINGMFIPKGV--VVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNI 427

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
             ++Y PFG+GPRNCIG+RFA+++ K+A+V +++NF F  C +T  P+      +LL
Sbjct: 428 DPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFGGLLL 484


>BC067436-1|AAH67436.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 7 protein.
          Length = 503

 Score =  174 bits (424), Expect = 2e-43
 Identities = 88/237 (37%), Positives = 145/237 (61%), Gaps = 8/237 (3%)

Query: 3   QAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYET 62
           Q  +   + ++  + DFLQ++ID  ++ +  ++T K    L D  + AQS++F+ AGYET
Sbjct: 255 QIKEGRLKETQKHRVDFLQLMID--SQNSKDSETHKA---LSDLELMAQSIIFIFAGYET 309

Query: 63  SSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPP 121
           +S++LSF I+ LAT PD+Q+ ++  +  +   K   +Y+ + Q++YL+  + ETLR++P 
Sbjct: 310 TSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPV 369

Query: 122 VARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
             R++R+C K   I G  +  GV   V IP Y LH D   + E  +F PERF    K + 
Sbjct: 370 AMRLERVCKKDVEINGMFIPKGV--VVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNI 427

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
             ++Y PFG+GPRNCIG+RFA+++ K+A+V +++NF F  C +T  P+      +LL
Sbjct: 428 DPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFGGLLL 484


>AF315325-1|AAG48618.1|  535|Homo sapiens cytochrome P450 variant
           3A7 protein.
          Length = 535

 Score =  174 bits (424), Expect = 2e-43
 Identities = 88/237 (37%), Positives = 145/237 (61%), Gaps = 8/237 (3%)

Query: 3   QAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYET 62
           Q  +   + ++  + DFLQ++ID  ++ +  ++T K    L D  + AQS++F+ AGYET
Sbjct: 255 QIKEGRLKETQKHRVDFLQLMID--SQNSKDSETHKA---LSDLELMAQSIIFIFAGYET 309

Query: 63  SSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPP 121
           +S++LSF I+ LAT PD+Q+ ++  +  +   K   +Y+ + Q++YL+  + ETLR++P 
Sbjct: 310 TSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPV 369

Query: 122 VARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
             R++R+C K   I G  +  GV   V IP Y LH D   + E  +F PERF    K + 
Sbjct: 370 AMRLERVCKKDVEINGMFIPKGV--VVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNI 427

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
             ++Y PFG+GPRNCIG+RFA+++ K+A+V +++NF F  C +T  P+      +LL
Sbjct: 428 DPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFGGLLL 484


>AF280107-3|AAG32289.1|  503|Homo sapiens cytochrome P450
           polypeptide 7 protein.
          Length = 503

 Score =  174 bits (424), Expect = 2e-43
 Identities = 88/237 (37%), Positives = 145/237 (61%), Gaps = 8/237 (3%)

Query: 3   QAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYET 62
           Q  +   + ++  + DFLQ++ID  ++ +  ++T K    L D  + AQS++F+ AGYET
Sbjct: 255 QIKEGRLKETQKHRVDFLQLMID--SQNSKDSETHKA---LSDLELMAQSIIFIFAGYET 309

Query: 63  SSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPP 121
           +S++LSF I+ LAT PD+Q+ ++  +  +   K   +Y+ + Q++YL+  + ETLR++P 
Sbjct: 310 TSSVLSFIIYELATHPDVQQKVQKEIDTVLPNKAPPTYDTVLQLEYLDMVVNETLRLFPV 369

Query: 122 VARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
             R++R+C K   I G  +  GV   V IP Y LH D   + E  +F PERF    K + 
Sbjct: 370 AMRLERVCKKDVEINGMFIPKGV--VVMIPSYVLHHDPKYWTEPEKFLPERFSKKNKDNI 427

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
             ++Y PFG+GPRNCIG+RFA+++ K+A+V +++NF F  C +T  P+      +LL
Sbjct: 428 DPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKPCKETQIPLKLRFGGLLL 484


>M18907-1|AAA35745.1|  503|Homo sapiens protein ( Human P450 mRNA
           encoding nifedipine oxidase, complete cds. ).
          Length = 503

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>DQ924960-1|ABI96208.1|  503|Homo sapiens cytochrome P450 family 3
           subfamily A polypeptide 4 protein.
          Length = 503

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>DQ005611-1|AAY16980.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 4 protein.
          Length = 503

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>BC101631-1|AAI01632.1|  503|Homo sapiens cytochrome P450, subfamily
           IIIA, polypeptide 4 protein.
          Length = 503

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>BC069418-1|AAH69418.1|  503|Homo sapiens cytochrome P450, family 3,
           subfamily A, polypeptide 4 protein.
          Length = 503

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>AJ563377-1|CAD91345.1|  353|Homo sapiens cytochrome P450 protein.
          Length = 353

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 114 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 168

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 169 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 228

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 229 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 286

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 287 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 345

Query: 251 ID 252
            D
Sbjct: 346 RD 347


>AJ563376-2|CAD91645.1|  430|Homo sapiens cytochrome P450 protein.
          Length = 430

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 191 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 245

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 246 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 305

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 306 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 363

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 364 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 422

Query: 251 ID 252
            D
Sbjct: 423 RD 424


>AJ563375-1|CAD91343.1|  503|Homo sapiens cytochrome P450 protein.
          Length = 503

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>AF280107-2|AAG32290.1|  503|Homo sapiens cytochrome P450
           polypeptide 4 protein.
          Length = 503

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>AF209389-1|AAF21034.1|  503|Homo sapiens cytochrome P450 IIIA4
           protein.
          Length = 503

 Score =  174 bits (423), Expect = 3e-43
 Identities = 89/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>M13785-1|AAA35742.1|  504|Homo sapiens protein ( Human liver
           glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
           complete cds. ).
          Length = 504

 Score =  173 bits (422), Expect = 4e-43
 Identities = 89/242 (36%), Positives = 149/242 (61%), Gaps = 8/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID + K + + ++ K    L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMID-SHKNSKETESHKA---LSDLELVAQSIIFIFAGYETTSSVLSFIM 319

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 320 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 379

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  + +  G  V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 380 KDVEING--MFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 437

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 438 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 496

Query: 251 ID 252
            D
Sbjct: 497 RD 498


>D00003-1|BAA00001.1|  504|Homo sapiens cytochrome P-450 protein.
          Length = 504

 Score =  173 bits (422), Expect = 4e-43
 Identities = 89/242 (36%), Positives = 149/242 (61%), Gaps = 8/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID + K + + ++ K    L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMID-SHKNSKETESHKA---LSDLELVAQSIIFIFAGYETTSSVLSFIM 319

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 320 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 379

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  + +  G  V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 380 KDVEING--MFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 437

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 438 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 496

Query: 251 ID 252
            D
Sbjct: 497 RD 498


>BC100981-1|AAI00982.1|  393|Homo sapiens CYP3A43 protein protein.
          Length = 393

 Score =  172 bits (419), Expect = 9e-43
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 12/254 (4%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 143 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 196

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 197 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 256

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQK 178
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PERF    K
Sbjct: 257 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPERFSKKNK 314

Query: 179 KDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
                + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + L
Sbjct: 315 DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI-L 373

Query: 239 KSAKGLWVRIELID 252
           +  K + +++ L D
Sbjct: 374 QPEKPIVLKVHLRD 387


>AY390425-1|AAQ92353.1|  503|Homo sapiens cytochrome P450 CYP3A43.1
           protein.
          Length = 503

 Score =  172 bits (419), Expect = 9e-43
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 12/254 (4%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQK 178
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PERF    K
Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPERFSKKNK 424

Query: 179 KDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
                + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + L
Sbjct: 425 DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI-L 483

Query: 239 KSAKGLWVRIELID 252
           +  K + +++ L D
Sbjct: 484 QPEKPIVLKVHLRD 497


>AY390424-1|AAQ92352.1|  503|Homo sapiens cytochrome P450 CYP3A43.3
           protein.
          Length = 503

 Score =  172 bits (419), Expect = 9e-43
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 12/254 (4%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLANKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQK 178
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PERF    K
Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPERFSKKNK 424

Query: 179 KDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
                + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + L
Sbjct: 425 DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI-L 483

Query: 239 KSAKGLWVRIELID 252
           +  K + +++ L D
Sbjct: 484 QPEKPIVLKVHLRD 497


>AF337813-1|AAK38841.1|  503|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 503

 Score =  172 bits (419), Expect = 9e-43
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 12/254 (4%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQK 178
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PERF    K
Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPERFSKKNK 424

Query: 179 KDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
                + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + L
Sbjct: 425 DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI-L 483

Query: 239 KSAKGLWVRIELID 252
           +  K + +++ L D
Sbjct: 484 QPEKPIVLKVHLRD 497


>AF319634-1|AAK00325.1|  503|Homo sapiens cytochrome P450 CYP3A43
           protein.
          Length = 503

 Score =  172 bits (419), Expect = 9e-43
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 12/254 (4%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQK 178
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PERF    K
Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPERFSKKNK 424

Query: 179 KDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
                + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + L
Sbjct: 425 DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI-L 483

Query: 239 KSAKGLWVRIELID 252
           +  K + +++ L D
Sbjct: 484 QPEKPIVLKVHLRD 497


>AF280108-1|AAG33009.1|  503|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 503

 Score =  172 bits (419), Expect = 9e-43
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 12/254 (4%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQK 178
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PERF    K
Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPERFSKKNK 424

Query: 179 KDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
                + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + L
Sbjct: 425 DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI-L 483

Query: 239 KSAKGLWVRIELID 252
           +  K + +++ L D
Sbjct: 484 QPEKPIVLKVHLRD 497


>AC011904-4|AAS07395.1|  503|Homo sapiens unknown protein.
          Length = 503

 Score =  172 bits (419), Expect = 9e-43
 Identities = 94/254 (37%), Positives = 147/254 (57%), Gaps = 12/254 (4%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQK 178
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PERF    K
Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPERFSKKNK 424

Query: 179 KDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLL 238
                + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + L
Sbjct: 425 DSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI-L 483

Query: 239 KSAKGLWVRIELID 252
           +  K + +++ L D
Sbjct: 484 QPEKPIVLKVHLRD 497


>X12387-1|CAA30944.1|  503|Homo sapiens protein ( Human mRNA for
           cytochrome P-450 (cyp3 locus). ).
          Length = 503

 Score =  172 bits (418), Expect = 1e-42
 Identities = 88/242 (36%), Positives = 146/242 (60%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  + +  G  V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEING--MFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>M14096-1|AAA35744.1|  503|Homo sapiens protein ( Human cytochrome
           P-450 nifedipine oxidase mRNA, complet cds. ).
          Length = 503

 Score =  171 bits (415), Expect = 3e-42
 Identities = 88/242 (36%), Positives = 145/242 (59%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  + +  G  V IP Y LH D   + E  +F PERF    K +   + Y PFG
Sbjct: 379 KDVEING--MFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>J04449-1|AAA35747.1|  502|Homo sapiens cytochrome P450 nifedipine
           oxidase protein.
          Length = 502

 Score =  171 bits (415), Expect = 3e-42
 Identities = 88/242 (36%), Positives = 145/242 (59%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AGYET+S++LSF +
Sbjct: 263 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGYETTSSVLSFIM 317

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 318 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 377

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  + +  G  V IP Y LH D   + E  +F PERF    K +   + Y PFG
Sbjct: 378 KDVEING--MFIPKGWVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYTYTPFG 435

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 436 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 494

Query: 251 ID 252
            D
Sbjct: 495 RD 496


>AF182273-1|AAF13598.1|  503|Homo sapiens cytochrome P450-3A4
           protein.
          Length = 503

 Score =  170 bits (414), Expect = 4e-42
 Identities = 88/242 (36%), Positives = 145/242 (59%), Gaps = 9/242 (3%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++  + DFLQ++ID    +  ++  A     L D  + AQS++F+ AG ET+S++LSF +
Sbjct: 264 TQKHRVDFLQLMIDSQNSKETESHKA-----LSDLELVAQSIIFIFAGCETTSSVLSFIM 318

Query: 72  HVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYPPVARVDRICT 130
           + LAT PD+Q+ L+  +  +   K   +Y+ + QM+YL+  + ETLR++P   R++R+C 
Sbjct: 319 YELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCK 378

Query: 131 KPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFG 190
           K   I G  +  GV   V IP Y LH D   + E  +F PERF    K +   ++Y PFG
Sbjct: 379 KDVEINGMFIPKGV--VVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFG 436

Query: 191 AGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIEL 250
           +GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+       LL+  K + +++E 
Sbjct: 437 SGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGG-LLQPEKPVVLKVES 495

Query: 251 ID 252
            D
Sbjct: 496 RD 497


>AF280109-1|AAG33010.1|  504|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 504

 Score =  168 bits (408), Expect = 2e-41
 Identities = 94/255 (36%), Positives = 147/255 (57%), Gaps = 13/255 (5%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPE-RFMDDQ 177
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PE RF    
Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPESRFSKKN 424

Query: 178 KKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVL 237
           K     + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + 
Sbjct: 425 KDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI- 483

Query: 238 LKSAKGLWVRIELID 252
           L+  K + +++ L D
Sbjct: 484 LQPEKPIVLKVHLRD 498


>AC011904-5|AAS07394.1|  504|Homo sapiens unknown protein.
          Length = 504

 Score =  168 bits (408), Expect = 2e-41
 Identities = 94/255 (36%), Positives = 147/255 (57%), Gaps = 13/255 (5%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPE-RFMDDQ 177
           +P V+RV R+C K   I G  +  G+  AV +P+Y LH D   + E  +F PE RF    
Sbjct: 367 FPVVSRVTRVCKKDIEINGVFIPKGL--AVMVPIYALHHDPKYWTEPEKFCPESRFSKKN 424

Query: 178 KKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVL 237
           K     + Y+PFGAGPRNCIG+RFA+ + K+A++  ++NF F  C +T  P+  D   + 
Sbjct: 425 KDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPI- 483

Query: 238 LKSAKGLWVRIELID 252
           L+  K + +++ L D
Sbjct: 484 LQPEKPIVLKVHLRD 498


>AF233621-1|AAF99275.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  137 bits (331), Expect = 4e-32
 Identities = 72/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA +VLAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYVLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233623-1|AAF99277.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (330), Expect = 5e-32
 Identities = 71/206 (34%), Positives = 115/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P  + F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPKTFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233625-1|AAF99279.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (329), Expect = 7e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233624-1|AAF99278.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (329), Expect = 7e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPENFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>M80647-1|AAA60618.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>BC093896-1|AAH93896.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score =  136 bits (328), Expect = 9e-32
 Identities = 77/250 (30%), Positives = 138/250 (55%), Gaps = 16/250 (6%)

Query: 3   QAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYET 62
           Q A+A  ++ + K  DF+ +L+       A+++  K    L D+ I A++  F+  G++T
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLL------LARDEDGKE---LSDEDIRAEADTFMFEGHDT 339

Query: 63  SSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMS---YELLAQMDYLEAFLQETLRIY 119
           +S+ +S+ +  LA  P+ QE  R  +QE+ KG+E+    ++ L Q+ +    ++E+LR Y
Sbjct: 340 TSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQY 399

Query: 120 PPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PPV  V R CT+   +P   + +  G    + +YG H +  ++P+++ + P RF  D  +
Sbjct: 400 PPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQ 458

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    Y+PF AGPRNCIG  FAM   ++ +   +  F+ SV  +T       K  ++L+
Sbjct: 459 QRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSV-DRTRKV--RRKPELILR 515

Query: 240 SAKGLWVRIE 249
           +  GLW+++E
Sbjct: 516 TENGLWLKVE 525


>BC093894-1|AAH93894.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score =  136 bits (328), Expect = 9e-32
 Identities = 77/250 (30%), Positives = 138/250 (55%), Gaps = 16/250 (6%)

Query: 3   QAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYET 62
           Q A+A  ++ + K  DF+ +L+       A+++  K    L D+ I A++  F+  G++T
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLL------LARDEDGKE---LSDEDIRAEADTFMFEGHDT 339

Query: 63  SSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMS---YELLAQMDYLEAFLQETLRIY 119
           +S+ +S+ +  LA  P+ QE  R  +QE+ KG+E+    ++ L Q+ +    ++E+LR Y
Sbjct: 340 TSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQY 399

Query: 120 PPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PPV  V R CT+   +P   + +  G    + +YG H +  ++P+++ + P RF  D  +
Sbjct: 400 PPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQ 458

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    Y+PF AGPRNCIG  FAM   ++ +   +  F+ SV  +T       K  ++L+
Sbjct: 459 QRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSV-DRTRKV--RRKPELILR 515

Query: 240 SAKGLWVRIE 249
           +  GLW+++E
Sbjct: 516 TENGLWLKVE 525


>BC069351-1|AAH69351.1|  531|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 2 homolog protein.
          Length = 531

 Score =  136 bits (328), Expect = 9e-32
 Identities = 77/250 (30%), Positives = 138/250 (55%), Gaps = 16/250 (6%)

Query: 3   QAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYET 62
           Q A+A  ++ + K  DF+ +L+       A+++  K    L D+ I A++  F+  G++T
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLL------LARDEDGKE---LSDEDIRAEADTFMFEGHDT 339

Query: 63  SSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMS---YELLAQMDYLEAFLQETLRIY 119
           +S+ +S+ +  LA  P+ QE  R  +QE+ KG+E+    ++ L Q+ +    ++E+LR Y
Sbjct: 340 TSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQY 399

Query: 120 PPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PPV  V R CT+   +P   + +  G    + +YG H +  ++P+++ + P RF  D  +
Sbjct: 400 PPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQ 458

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    Y+PF AGPRNCIG  FAM   ++ +   +  F+ SV  +T       K  ++L+
Sbjct: 459 QRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSV-DRTRKV--RRKPELILR 515

Query: 240 SAKGLWVRIE 249
           +  GLW+++E
Sbjct: 516 TENGLWLKVE 525


>BC041157-1|AAH41157.1|  534|Homo sapiens thromboxane A synthase 1
           (platelet, cytochrome P450, family 5, subfamily A)
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>BC014117-1|AAH14117.1|  466|Homo sapiens TBXAS1 protein protein.
          Length = 466

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 262 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 320

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 321 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 378

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 379 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 438

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 439 PETQVPLQLESKSA-LGPKNGVYIKI 463


>AK223466-1|BAD97186.1|  534|Homo sapiens thromboxane A synthase 1
           (platelet, cytochrome P450, family 5, subfamily A) iso
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AK096820-1|BAC04868.1|  531|Homo sapiens protein ( Homo sapiens
           cDNA FLJ39501 fis, clone PROST2016980, moderately
           similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
          Length = 531

 Score =  136 bits (328), Expect = 9e-32
 Identities = 77/250 (30%), Positives = 138/250 (55%), Gaps = 16/250 (6%)

Query: 3   QAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYET 62
           Q A+A  ++ + K  DF+ +L+       A+++  K    L D+ I A++  F+  G++T
Sbjct: 289 QGAEAWLKAKQGKTLDFIDVLL------LARDEDGKE---LSDEDIRAEADTFMFEGHDT 339

Query: 63  SSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMS---YELLAQMDYLEAFLQETLRIY 119
           +S+ +S+ +  LA  P+ QE  R  +QE+ KG+E+    ++ L Q+ +    ++E+LR Y
Sbjct: 340 TSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELEWDDLTQLPFTTMCIKESLRQY 399

Query: 120 PPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PPV  V R CT+   +P   + +  G    + +YG H +  ++P+++ + P RF  D  +
Sbjct: 400 PPVTLVSRQCTEDIKLPDGRI-IPKGIICLVSIYGTHHNPTVWPDSKVYNPYRFDPDNPQ 458

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    Y+PF AGPRNCIG  FAM   ++ +   +  F+ SV  +T       K  ++L+
Sbjct: 459 QRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSV-DRTRKV--RRKPELILR 515

Query: 240 SAKGLWVRIE 249
           +  GLW+++E
Sbjct: 516 TENGLWLKVE 525


>AF233622-1|AAF99276.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAEDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233620-1|AAF99274.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233619-1|AAF99273.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233618-1|AAF99272.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233617-1|AAF99271.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233616-1|AAF99270.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF233615-1|AAF99269.1|  534|Homo sapiens thromboxane synthase
           protein.
          Length = 534

 Score =  136 bits (328), Expect = 9e-32
 Identities = 71/206 (34%), Positives = 114/206 (55%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+R  ++  K+ ++ ++  F+F  C
Sbjct: 447 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQAC 506

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 507 PETQVPLQLESKSA-LGPKNGVYIKI 531


>AF236085-1|AAG15889.1|  524|Homo sapiens CYP4F11 protein.
          Length = 524

 Score =  135 bits (327), Expect = 1e-31
 Identities = 74/244 (30%), Positives = 140/244 (57%), Gaps = 17/244 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           +  ++SK  DF+ +L+       ++++  K    L D+ I A++  F+  G++T+++ LS
Sbjct: 288 KNKAKSKTLDFIDVLL------LSKDEDGKE---LSDEDIRAEADTFMFEGHDTTASGLS 338

Query: 69  FAIHVLATKPDLQETLRAHVQEMTKGKE---MSYELLAQMDYLEAFLQETLRIYPPVARV 125
           + ++ LA  P+ QE  R  VQE+ K +E   + ++ LAQ+ +L   ++E+LR++PPV  +
Sbjct: 339 WVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVI 398

Query: 126 DRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHL 185
            R CT+ +++P   V +  G    I + G+H +  ++P+   + P RF  +  K+R    
Sbjct: 399 SRCCTQDFVLPDGRV-IPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLA 457

Query: 186 YLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLW 245
           ++PF AGPRNCIG  FAM   K+ +   + +F+  +    ++P    K  ++L++  GLW
Sbjct: 458 FIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFR--ILPTHIEP--RRKPELILRAEGGLW 513

Query: 246 VRIE 249
           +R+E
Sbjct: 514 LRVE 517


>BC016853-1|AAH16853.1|  524|Homo sapiens CYP4F11 protein protein.
          Length = 524

 Score =  134 bits (325), Expect = 2e-31
 Identities = 74/244 (30%), Positives = 139/244 (56%), Gaps = 17/244 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           +  ++SK  DF+ +L+       ++++  K    L D+ I A++  F+  G++T+++ LS
Sbjct: 288 KNKAKSKTLDFIDVLL------LSKDEDGKE---LSDEDIRAEADTFMFEGHDTTASGLS 338

Query: 69  FAIHVLATKPDLQETLRAHVQEMTKGKE---MSYELLAQMDYLEAFLQETLRIYPPVARV 125
           + ++ LA  P+ QE  R  VQE+ K +E   + ++ LAQ+ +L   ++E+LR++PPV  +
Sbjct: 339 WVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVI 398

Query: 126 DRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHL 185
            R CT+ +++P   V +  G    I + G+H +  ++P+   + P RF  +  K+R    
Sbjct: 399 SRCCTQDFVLPDGRV-IPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLA 457

Query: 186 YLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLW 245
           ++PF AGPRNCIG  FAM   K+ +   + +F+  +     +P    K  ++L++  GLW
Sbjct: 458 FIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFR--ILPTHTEP--RRKPELILRAEGGLW 513

Query: 246 VRIE 249
           +R+E
Sbjct: 514 LRVE 517


>D34625-1|BAA07011.1|  533|Homo sapiens thromboxane synthase
           protein.
          Length = 533

 Score =  134 bits (323), Expect = 4e-31
 Identities = 70/206 (33%), Positives = 113/206 (54%), Gaps = 7/206 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQ- 104
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E  +  
Sbjct: 329 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 387

Query: 105 --MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 388 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 445

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVC 222
           P    F PERF  + ++      YLPFGAGPR+C+G+   ++  K+ ++ ++  F+F  C
Sbjct: 446 PSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHKFRFQAC 505

Query: 223 SKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +T  P+  + ++  L    G++++I
Sbjct: 506 PETQVPLQLESKSA-LGPKNGVYIKI 530


>BC035350-1|AAH35350.1|  524|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 12 protein.
          Length = 524

 Score =  134 bits (323), Expect = 4e-31
 Identities = 69/215 (32%), Positives = 125/215 (58%), Gaps = 8/215 (3%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKG---KEMSY 99
           L D+ I A++  F+  G++T+++ LS+ ++ LA  P+ QE  R  VQE+ K    KE+ +
Sbjct: 313 LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEW 372

Query: 100 ELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDE 159
           + LAQ+ +L   ++E+LR++PP   + R CT+  ++P   V +  G    I + G+H + 
Sbjct: 373 DDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRV-IPKGITCLIDIIGVHHNP 431

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P+   + P RF  +  K R    ++PF AGPRNCIG  FAM   K+ +  ++ +F+F
Sbjct: 432 TVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRIELIDLS 254
                  +P    K  +++++  GLW+R+E +++S
Sbjct: 492 --LPDHTEP--RRKLELIMRAEGGLWLRVEPLNVS 522


>AC004523-1|AAC11543.1|  458|Homo sapiens F22329_1 protein.
          Length = 458

 Score =  134 bits (323), Expect = 4e-31
 Identities = 69/215 (32%), Positives = 125/215 (58%), Gaps = 8/215 (3%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKG---KEMSY 99
           L D+ I A++  F+  G++T+++ LS+ ++ LA  P+ QE  R  VQE+ K    KE+ +
Sbjct: 247 LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEW 306

Query: 100 ELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDE 159
           + LAQ+ +L   ++E+LR++PP   + R CT+  ++P   V +  G    I + G+H + 
Sbjct: 307 DDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRV-IPKGITCLIDIIGVHHNP 365

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P+   + P RF  +  K R    ++PF AGPRNCIG  FAM   K+ +  ++ +F+F
Sbjct: 366 TVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 425

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRIELIDLS 254
                  +P    K  +++++  GLW+R+E +++S
Sbjct: 426 --LPDHTEP--RRKLELIMRAEGGLWLRVEPLNVS 456


>AF133298-1|AAD49566.1|  520|Homo sapiens cytochrome P450 protein.
          Length = 520

 Score =  133 bits (321), Expect = 7e-31
 Identities = 78/252 (30%), Positives = 139/252 (55%), Gaps = 17/252 (6%)

Query: 8   ERRSSESKKG--DFLQI-----LIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           ERR + + +G  DFLQ       +DF        D   +E  L D+ I A++  F+  G+
Sbjct: 273 ERRRTLTSQGVDDFLQAKAKSKTLDFIDVLLLSEDKNGKE--LSDEDIRAEADTFMFGGH 330

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLR 117
           +T+++ LS+ ++ LA  P+ QE  R  VQE+ K    KE+ ++ LAQ+ +L   L+E+LR
Sbjct: 331 DTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLR 390

Query: 118 IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQ 177
           ++PP+    R CT+  ++P + V +  G+   I ++ +H +  ++P+   + P RF  + 
Sbjct: 391 LHPPIPTFARGCTQDVVLPDSRV-IPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPEN 449

Query: 178 KKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVL 237
            + R    ++PF AGPRNCIG +FAM   K+ +   +   +F +     +P    +  ++
Sbjct: 450 AQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTL--LRFRILPDHREPRRTPE--IV 505

Query: 238 LKSAKGLWVRIE 249
           L++  GLW+R+E
Sbjct: 506 LRAEDGLWLRVE 517


>AY792513-1|AAV40834.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 3 protein.
          Length = 520

 Score =  132 bits (319), Expect = 1e-30
 Identities = 78/241 (32%), Positives = 136/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LAQ+ +L   ++E+LR++PPV  V R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRC 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
           CT+  ++P   V +  G    I V+G H +  ++P+   + P RF     K+R    ++P
Sbjct: 402 CTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQAFAMAEMKVVLGLTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>AY358977-1|AAQ89336.1|  524|Homo sapiens CYP4F12 protein.
          Length = 524

 Score =  132 bits (319), Expect = 1e-30
 Identities = 68/214 (31%), Positives = 124/214 (57%), Gaps = 8/214 (3%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKG---KEMSY 99
           L D+ I A++  F+  G++T+++ LS+ ++ LA  P+ QE  R  VQE+ K    KE+ +
Sbjct: 313 LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEW 372

Query: 100 ELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDE 159
           + LAQ+ +L   ++E+LR++PP   + R CT+  ++P   V +  G    I + G+H + 
Sbjct: 373 DDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRV-IPKGITCLIDIIGVHHNP 431

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P+   + P RF  +  K R    ++PF AGPRNCIG  FAM   K+ +  ++ +F+F
Sbjct: 432 TVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRIELIDL 253
                  +P    K  +++++  GLW+R+E +++
Sbjct: 492 --LPDHTEP--RRKLELIMRAEGGLWLRVEPLNV 521


>AY008841-1|AAG33247.1|  524|Homo sapiens cytochrome P450 isoform
           4F12 protein.
          Length = 524

 Score =  132 bits (319), Expect = 1e-30
 Identities = 68/214 (31%), Positives = 124/214 (57%), Gaps = 8/214 (3%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKG---KEMSY 99
           L D+ I A++  F+  G++T+++ LS+ ++ LA  P+ QE  R  VQE+ K    KE+ +
Sbjct: 313 LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEW 372

Query: 100 ELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDE 159
           + LAQ+ +L   ++E+LR++PP   + R CT+  ++P   V +  G    I + G+H + 
Sbjct: 373 DDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRV-IPKGITCLIDIIGVHHNP 431

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P+   + P RF  +  K R    ++PF AGPRNCIG  FAM   K+ +  ++ +F+F
Sbjct: 432 TVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRIELIDL 253
                  +P    K  +++++  GLW+R+E +++
Sbjct: 492 --LPDHTEP--RRKLELIMRAEGGLWLRVEPLNV 521


>AB035131-1|BAB18270.1|  524|Homo sapiens cytochrome P450 protein.
          Length = 524

 Score =  132 bits (319), Expect = 1e-30
 Identities = 68/214 (31%), Positives = 124/214 (57%), Gaps = 8/214 (3%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKG---KEMSY 99
           L D+ I A++  F+  G++T+++ LS+ ++ LA  P+ QE  R  VQE+ K    KE+ +
Sbjct: 313 LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEW 372

Query: 100 ELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDE 159
           + LAQ+ +L   ++E+LR++PP   + R CT+  ++P   V +  G    I + G+H + 
Sbjct: 373 DDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRV-IPKGITCLIDIIGVHHNP 431

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P+   + P RF  +  K R    ++PF AGPRNCIG  FAM   K+ +  ++ +F+F
Sbjct: 432 TVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRIELIDL 253
                  +P    K  +++++  GLW+R+E +++
Sbjct: 492 --LPDHTEP--RRKLELIMRAEGGLWLRVEPLNV 521


>AB035130-1|BAB18269.1|  524|Homo sapiens cytochrome P450 protein.
          Length = 524

 Score =  132 bits (319), Expect = 1e-30
 Identities = 68/214 (31%), Positives = 124/214 (57%), Gaps = 8/214 (3%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKG---KEMSY 99
           L D+ I A++  F+  G++T+++ LS+ ++ LA  P+ QE  R  VQE+ K    KE+ +
Sbjct: 313 LSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEW 372

Query: 100 ELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDE 159
           + LAQ+ +L   ++E+LR++PP   + R CT+  ++P   V +  G    I + G+H + 
Sbjct: 373 DDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRV-IPKGITCLIDIIGVHHNP 431

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P+   + P RF  +  K R    ++PF AGPRNCIG  FAM   K+ +  ++ +F+F
Sbjct: 432 TVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRF 491

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRIELIDL 253
                  +P    K  +++++  GLW+R+E +++
Sbjct: 492 --LPDHTEP--RRKLELIMRAEGGLWLRVEPLNV 521


>AF054821-1|AAC08589.1|  520|Homo sapiens cytochrome P-450 protein.
          Length = 520

 Score =  131 bits (317), Expect = 2e-30
 Identities = 77/241 (31%), Positives = 136/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LAQ+ +L   ++E+LR++PPV  V R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRC 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
           CT+  ++P   V +  G    I V+G H +  ++P+   + P RF     K+R    ++P
Sbjct: 402 CTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  G+W+R+
Sbjct: 461 FSAGPRNCIGQAFAMAEMKVVLGLTL--LRFRVLPDHTEP--RRKPELVLRAEGGIWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>D12620-1|BAA02144.1|  520|Homo sapiens cytochrome P-450LTBV
           protein.
          Length = 520

 Score =  131 bits (316), Expect = 3e-30
 Identities = 78/241 (32%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LAQ+ +L   ++E+LR++PPV  V R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRC 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
           CT+  ++P   V +  G    I V+G H +  ++P+   + P RF     K+R    ++P
Sbjct: 402 CTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +    F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQAFAMAEMKVVLGLTL--LAFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>AB002461-1|BAA25991.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score =  131 bits (316), Expect = 3e-30
 Identities = 78/241 (32%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LAQ+ +L   ++E+LR++PPV  V R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRC 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
           CT+  ++P   V +  G    I V+G H +  ++P+   + P RF     K+R    ++P
Sbjct: 402 CTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +    F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQAFAMAEMKVVLGLTL--LAFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>AB002454-1|BAA25990.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score =  131 bits (316), Expect = 3e-30
 Identities = 78/241 (32%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LAQ+ +L   ++E+LR++PPV  V R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRC 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
           CT+  ++P   V +  G    I V+G H +  ++P+   + P RF     K+R    ++P
Sbjct: 402 CTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +    F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQAFAMAEMKVVLGLTL--LAFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>U02388-1|AAC50052.2|  520|Homo sapiens cytochrome P450 4F2 protein.
          Length = 520

 Score =  129 bits (311), Expect = 1e-29
 Identities = 75/241 (31%), Positives = 136/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T++++LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASVLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LA + +L   ++E+LR++PPV  + R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRVHPPVPVISRH 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
            T+  ++P   V +  G    I V+G H +  ++P+   + P RF  +  K+R    ++P
Sbjct: 402 VTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQTFAMAEMKVVLALTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>AJ563378-3|CAD91347.1|  173|Homo sapiens hypothetical protein
           protein.
          Length = 173

 Score =  128 bits (310), Expect = 1e-29
 Identities = 62/156 (39%), Positives = 97/156 (62%), Gaps = 6/156 (3%)

Query: 98  SYELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHM 157
           +Y+ + QM+YL+  + ETLR++P   R++R C K   I G  V +  G  V IP Y LH 
Sbjct: 17  TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEING--VFIPKGSMVVIPTYALHH 74

Query: 158 DEDIYPEAREFKPERFMDDQKKDR-PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKN 216
           D   + E  EF+PERF   +KKD    ++Y PFG GPRNCIG+RFA+++ K+A++ +++N
Sbjct: 75  DPKYWTEPEEFRPERF--SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQN 132

Query: 217 FKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIELID 252
           F F  C +T  P+  D +  LL+  K + ++++  D
Sbjct: 133 FSFKPCKETQIPLKLDTQG-LLQPEKPIVLKVDSRD 167


>AJ563378-2|CAD91647.1|  160|Homo sapiens cytochrome P450 protein.
          Length = 160

 Score =  128 bits (310), Expect = 1e-29
 Identities = 62/156 (39%), Positives = 97/156 (62%), Gaps = 6/156 (3%)

Query: 98  SYELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHM 157
           +Y+ + QM+YL+  + ETLR++P   R++R C K   I G  V +  G  V IP Y LH 
Sbjct: 4   TYDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEING--VFIPKGSMVVIPTYALHH 61

Query: 158 DEDIYPEAREFKPERFMDDQKKDR-PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKN 216
           D   + E  EF+PERF   +KKD    ++Y PFG GPRNCIG+RFA+++ K+A++ +++N
Sbjct: 62  DPKYWTEPEEFRPERF--SKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQN 119

Query: 217 FKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIELID 252
           F F  C +T  P+  D +  LL+  K + ++++  D
Sbjct: 120 FSFKPCKETQIPLKLDTQG-LLQPEKPIVLKVDSRD 154


>D26480-1|BAA05490.1|  520|Homo sapiens leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score =  126 bits (305), Expect = 6e-29
 Identities = 75/241 (31%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LA + +L   ++E+LR++PPV  + R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRH 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
            T+  ++P   V +  G    I V+G H +  ++P+   + P RF  +  K+R    ++P
Sbjct: 402 VTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQTFAMAEMKVVLALTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>BC067439-1|AAH67439.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score =  126 bits (305), Expect = 6e-29
 Identities = 75/241 (31%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LA + +L   ++E+LR++PPV  + R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRH 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
            T+  ++P   V +  G    I V+G H +  ++P+   + P RF  +  K+R    ++P
Sbjct: 402 VTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQTFAMAEMKVVLALTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>BC067437-1|AAH67437.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score =  126 bits (305), Expect = 6e-29
 Identities = 75/241 (31%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LA + +L   ++E+LR++PPV  + R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRH 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
            T+  ++P   V +  G    I V+G H +  ++P+   + P RF  +  K+R    ++P
Sbjct: 402 VTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQTFAMAEMKVVLALTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>AF467894-1|AAL67578.1|  520|Homo sapiens cytochrome P450, subfamily
           IVF, polypeptide 2 protein.
          Length = 520

 Score =  126 bits (305), Expect = 6e-29
 Identities = 75/241 (31%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LA + +L   ++E+LR++PPV  + R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRH 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
            T+  ++P   V +  G    I V+G H +  ++P+   + P RF  +  K+R    ++P
Sbjct: 402 VTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQTFAMAEMKVVLALTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>AC005336-1|AAC27730.1|  520|Homo sapiens CYP4F2 protein.
          Length = 520

 Score =  126 bits (305), Expect = 6e-29
 Identities = 75/241 (31%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LA + +L   ++E+LR++PPV  + R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRH 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
            T+  ++P   V +  G    I V+G H +  ++P+   + P RF  +  K+R    ++P
Sbjct: 402 VTQDIVLPDGRV-IPKGIICLISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQTFAMAEMKVVLALTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>BC067440-1|AAH67440.1|  520|Homo sapiens cytochrome P450, family 4,
           subfamily F, polypeptide 2 protein.
          Length = 520

 Score =  126 bits (303), Expect = 1e-28
 Identities = 75/241 (31%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LA + +L   ++E+LR++PPV  + R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRH 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
            T+  ++P   V +  G    I V+G H +  ++P+   + P RF  +  K+R    ++P
Sbjct: 402 VTQDIVLPDGRV-IPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQTFAMAEMKVVLALTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>AB015306-1|BAA75823.1|  520|Homo sapiens Leukotriene B4
           omega-hydroxylase protein.
          Length = 520

 Score =  126 bits (303), Expect = 1e-28
 Identities = 75/241 (31%), Positives = 135/241 (56%), Gaps = 17/241 (7%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           ++SK  DF+ +L+       ++++  K+   L D+ I A++  F+  G++T+++ LS+ +
Sbjct: 291 AKSKTLDFIDVLL------LSKDEDGKK---LSDEDIRAEADTFMFEGHDTTASGLSWVL 341

Query: 72  HVLATKPDLQETLRAHVQEMTKG---KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRI 128
           + LA  P+ QE  R  VQE+ K    KE+ ++ LA + +L   ++E+LR++PPV  + R 
Sbjct: 342 YHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRH 401

Query: 129 CTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLP 188
            T+  ++P   V +  G    I V+G H +  ++P+   + P RF  +  K+R    ++P
Sbjct: 402 VTQDIVLPDGRV-IPKGIICLISVFGTHHNPAMWPDPEVYDPFRFDPENIKERSPLAFIP 460

Query: 189 FGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           F AGPRNCIG  FAM   K+ +   +   +F V     +P    K  ++L++  GLW+R+
Sbjct: 461 FSAGPRNCIGQTFAMAEMKVVLALTL--LRFRVLPDHTEP--RRKPELVLRAEGGLWLRV 516

Query: 249 E 249
           E
Sbjct: 517 E 517


>AY358631-1|AAQ88994.1|  505|Homo sapiens EPSW3060 protein.
          Length = 505

 Score =  119 bits (286), Expect = 1e-26
 Identities = 73/244 (29%), Positives = 133/244 (54%), Gaps = 18/244 (7%)

Query: 6   KAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSST 65
           K ++ +++ ++ DFL IL+  +AK     D ++ ++        A+   F+ AG++T+S+
Sbjct: 271 KLKQDTTQKRRWDFLDILL--SAKSENTKDFSEADL-------QAEVKTFMFAGHDTTSS 321

Query: 66  LLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPVAR 124
            +S+ ++ LA  P+ Q+  R  ++E+   G  +++E L+QM Y    ++E LR+Y PV  
Sbjct: 322 AISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVN 381

Query: 125 VDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
           + R+  KP   P G ++  G+   V I ++ LH +   + + + F P RF  +  +    
Sbjct: 382 ISRLLDKPITFPDGRSLPAGI--TVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHP 439

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV-CSKTMDPIDFDKRAVLLKSAK 242
           + ++PF AG RNCIG  FA+I  K+A+   +  FK +   S+   P+    R V+LKS  
Sbjct: 440 YAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPV----RQVVLKSKN 495

Query: 243 GLWV 246
           G+ V
Sbjct: 496 GIHV 499


>AY262056-1|AAO89257.1|  505|Homo sapiens cytochrome P450 protein.
          Length = 505

 Score =  119 bits (286), Expect = 1e-26
 Identities = 73/244 (29%), Positives = 133/244 (54%), Gaps = 18/244 (7%)

Query: 6   KAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSST 65
           K ++ +++ ++ DFL IL+  +AK     D ++ ++        A+   F+ AG++T+S+
Sbjct: 271 KLKQDTTQKRRWDFLDILL--SAKSENTKDFSEADL-------QAEVKTFMFAGHDTTSS 321

Query: 66  LLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPVAR 124
            +S+ ++ LA  P+ Q+  R  ++E+   G  +++E L+QM Y    ++E LR+Y PV  
Sbjct: 322 AISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVN 381

Query: 125 VDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
           + R+  KP   P G ++  G+   V I ++ LH +   + + + F P RF  +  +    
Sbjct: 382 ISRLLDKPITFPDGRSLPAGI--TVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHP 439

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV-CSKTMDPIDFDKRAVLLKSAK 242
           + ++PF AG RNCIG  FA+I  K+A+   +  FK +   S+   P+    R V+LKS  
Sbjct: 440 YAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPV----RQVVLKSKN 495

Query: 243 GLWV 246
           G+ V
Sbjct: 496 GIHV 499


>AL450996-2|CAH71036.1|  505|Homo sapiens cytochrome P450, family 4,
           subfamily Z, polypeptide 1 protein.
          Length = 505

 Score =  119 bits (286), Expect = 1e-26
 Identities = 73/244 (29%), Positives = 133/244 (54%), Gaps = 18/244 (7%)

Query: 6   KAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSST 65
           K ++ +++ ++ DFL IL+  +AK     D ++ ++        A+   F+ AG++T+S+
Sbjct: 271 KLKQDTTQKRRWDFLDILL--SAKSENTKDFSEADL-------QAEVKTFMFAGHDTTSS 321

Query: 66  LLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPVAR 124
            +S+ ++ LA  P+ Q+  R  ++E+   G  +++E L+QM Y    ++E LR+Y PV  
Sbjct: 322 AISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVN 381

Query: 125 VDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
           + R+  KP   P G ++  G+   V I ++ LH +   + + + F P RF  +  +    
Sbjct: 382 ISRLLDKPITFPDGRSLPAGI--TVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHP 439

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV-CSKTMDPIDFDKRAVLLKSAK 242
           + ++PF AG RNCIG  FA+I  K+A+   +  FK +   S+   P+    R V+LKS  
Sbjct: 440 YAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPV----RQVVLKSKN 495

Query: 243 GLWV 246
           G+ V
Sbjct: 496 GIHV 499


>AL135960-6|CAI19734.1|  505|Homo sapiens cytochrome P450, family 4,
           subfamily Z, polypeptide 1 protein.
          Length = 505

 Score =  119 bits (286), Expect = 1e-26
 Identities = 73/244 (29%), Positives = 133/244 (54%), Gaps = 18/244 (7%)

Query: 6   KAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSST 65
           K ++ +++ ++ DFL IL+  +AK     D ++ ++        A+   F+ AG++T+S+
Sbjct: 271 KLKQDTTQKRRWDFLDILL--SAKSENTKDFSEADL-------QAEVKTFMFAGHDTTSS 321

Query: 66  LLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPVAR 124
            +S+ ++ LA  P+ Q+  R  ++E+   G  +++E L+QM Y    ++E LR+Y PV  
Sbjct: 322 AISWILYCLAKYPEHQQRCRDEIRELLGDGSSITWEHLSQMPYTTMCIKECLRLYAPVVN 381

Query: 125 VDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
           + R+  KP   P G ++  G+   V I ++ LH +   + + + F P RF  +  +    
Sbjct: 382 ISRLLDKPITFPDGRSLPAGI--TVFINIWALHHNPYFWEDPQVFNPLRFSRENSEKIHP 439

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV-CSKTMDPIDFDKRAVLLKSAK 242
           + ++PF AG RNCIG  FA+I  K+A+   +  FK +   S+   P+    R V+LKS  
Sbjct: 440 YAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSRPPQPV----RQVVLKSKN 495

Query: 243 GLWV 246
           G+ V
Sbjct: 496 GIHV 499


>BC028102-1|AAH28102.1|  509|Homo sapiens cytochrome P450, family 4,
           subfamily X, polypeptide 1 protein.
          Length = 509

 Score =  118 bits (285), Expect = 2e-26
 Identities = 72/250 (28%), Positives = 129/250 (51%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQA   +  + + K  DFL I++  +AK+ + +          D  + ++   FL+AG++
Sbjct: 269 LQAGVKQDNTPKRKYQDFLDIVL--SAKDESGSS-------FSDIDVHSEVSTFLLAGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYP 120
           T +  +S+ ++ LA  P+ QE  R  V+ +   G  ++++ L +M Y    ++ET R+ P
Sbjct: 320 TLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIP 379

Query: 121 PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
            V  + R  +KP   P G T+  G+   V + ++GLH +  ++   + F P RF  +   
Sbjct: 380 AVPSISRDLSKPLTFPDGCTLPAGI--TVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R  + YLPF AG RNCIG  FAMI  K+ +  ++ +F+  V      P+ F     +LK
Sbjct: 438 QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR--VTPDPTRPLTFPNH-FILK 494

Query: 240 SAKGLWVRIE 249
              G+++ ++
Sbjct: 495 PKNGMYLHLK 504


>AY358537-1|AAQ88901.1|  509|Homo sapiens EFSW1929 protein.
          Length = 509

 Score =  118 bits (285), Expect = 2e-26
 Identities = 72/250 (28%), Positives = 129/250 (51%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQA   +  + + K  DFL I++  +AK+ + +          D  + ++   FL+AG++
Sbjct: 269 LQAGVKQDNTPKRKYQDFLDIVL--SAKDESGSS-------FSDIDVHSEVSTFLLAGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYP 120
           T +  +S+ ++ LA  P+ QE  R  V+ +   G  ++++ L +M Y    ++ET R+ P
Sbjct: 320 TLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIP 379

Query: 121 PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
            V  + R  +KP   P G T+  G+   V + ++GLH +  ++   + F P RF  +   
Sbjct: 380 AVPSISRDLSKPLTFPDGCTLPAGI--TVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R  + YLPF AG RNCIG  FAMI  K+ +  ++ +F+  V      P+ F     +LK
Sbjct: 438 QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR--VTPDPTRPLTFPNH-FILK 494

Query: 240 SAKGLWVRIE 249
              G+++ ++
Sbjct: 495 PKNGMYLHLK 504


>AM040940-1|CAJ13826.1|  509|Homo sapiens cytochrome P450 protein.
          Length = 509

 Score =  118 bits (285), Expect = 2e-26
 Identities = 72/250 (28%), Positives = 129/250 (51%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQA   +  + + K  DFL I++  +AK+ + +          D  + ++   FL+AG++
Sbjct: 269 LQAGVKQDNTPKRKYQDFLDIVL--SAKDESGSS-------FSDIDVHSEVSTFLLAGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYP 120
           T +  +S+ ++ LA  P+ QE  R  V+ +   G  ++++ L +M Y    ++ET R+ P
Sbjct: 320 TLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIP 379

Query: 121 PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
            V  + R  +KP   P G T+  G+   V + ++GLH +  ++   + F P RF  +   
Sbjct: 380 AVPSISRDLSKPLTFPDGCTLPAGI--TVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R  + YLPF AG RNCIG  FAMI  K+ +  ++ +F+  V      P+ F     +LK
Sbjct: 438 QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR--VTPDPTRPLTFPNH-FILK 494

Query: 240 SAKGLWVRIE 249
              G+++ ++
Sbjct: 495 PKNGMYLHLK 504


>AL450996-1|CAH71035.1|  509|Homo sapiens cytochrome P450, family 4,
           subfamily X, polypeptide 1 protein.
          Length = 509

 Score =  118 bits (285), Expect = 2e-26
 Identities = 72/250 (28%), Positives = 129/250 (51%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQA   +  + + K  DFL I++  +AK+ + +          D  + ++   FL+AG++
Sbjct: 269 LQAGVKQDNTPKRKYQDFLDIVL--SAKDESGSS-------FSDIDVHSEVSTFLLAGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYP 120
           T +  +S+ ++ LA  P+ QE  R  V+ +   G  ++++ L +M Y    ++ET R+ P
Sbjct: 320 TLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIP 379

Query: 121 PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
            V  + R  +KP   P G T+  G+   V + ++GLH +  ++   + F P RF  +   
Sbjct: 380 AVPSISRDLSKPLTFPDGCTLPAGI--TVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R  + YLPF AG RNCIG  FAMI  K+ +  ++ +F+  V      P+ F     +LK
Sbjct: 438 QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR--VTPDPTRPLTFPNH-FILK 494

Query: 240 SAKGLWVRIE 249
              G+++ ++
Sbjct: 495 PKNGMYLHLK 504


>AK131355-1|BAD18508.1|  508|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16384 fis, clone TLIVE2007607, weakly  similar
           to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 508

 Score =  118 bits (285), Expect = 2e-26
 Identities = 72/250 (28%), Positives = 129/250 (51%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQA   +  + + K  DFL I++  +AK+ + +          D  + ++   FL+AG++
Sbjct: 268 LQAGVKQDNTPKRKYQDFLDIVL--SAKDESGSS-------FSDIDVHSEVSTFLLAGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYP 120
           T +  +S+ ++ LA  P+ QE  R  V+ +   G  ++++ L +M Y    ++ET R+ P
Sbjct: 319 TLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIP 378

Query: 121 PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
            V  + R  +KP   P G T+  G+   V + ++GLH +  ++   + F P RF  +   
Sbjct: 379 AVPSISRDLSKPLTFPDGCTLPAGI--TVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R  + YLPF AG RNCIG  FAMI  K+ +  ++ +F+  V      P+ F     +LK
Sbjct: 437 QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR--VTPDPTRPLTFPNH-FILK 493

Query: 240 SAKGLWVRIE 249
              G+++ ++
Sbjct: 494 PKNGMYLHLK 503


>AK098065-1|BAC05226.1|  509|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
           CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 509

 Score =  118 bits (285), Expect = 2e-26
 Identities = 72/250 (28%), Positives = 129/250 (51%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQA   +  + + K  DFL I++  +AK+ + +          D  + ++   FL+AG++
Sbjct: 269 LQAGVKQDNTPKRKYQDFLDIVL--SAKDESGSS-------FSDIDVHSEVSTFLLAGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYP 120
           T +  +S+ ++ LA  P+ QE  R  V+ +   G  ++++ L +M Y    ++ET R+ P
Sbjct: 320 TLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIP 379

Query: 121 PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
            V  + R  +KP   P G T+  G+   V + ++GLH +  ++   + F P RF  +   
Sbjct: 380 AVPSISRDLSKPLTFPDGCTLPAGI--TVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R  + YLPF AG RNCIG  FAMI  K+ +  ++ +F+  V      P+ F     +LK
Sbjct: 438 QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR--VTPDPTRPLTFPNH-FILK 494

Query: 240 SAKGLWVRIE 249
              G+++ ++
Sbjct: 495 PKNGMYLHLK 504


>AK091806-1|BAC03751.1|  444|Homo sapiens protein ( Homo sapiens
           cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
           CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
          Length = 444

 Score =  118 bits (285), Expect = 2e-26
 Identities = 72/250 (28%), Positives = 129/250 (51%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQA   +  + + K  DFL I++  +AK+ + +          D  + ++   FL+AG++
Sbjct: 204 LQAGVKQDNTPKRKYQDFLDIVL--SAKDESGSS-------FSDIDVHSEVSTFLLAGHD 254

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYP 120
           T +  +S+ ++ LA  P+ QE  R  V+ +   G  ++++ L +M Y    ++ET R+ P
Sbjct: 255 TLAASISWILYCLALNPEHQERCREEVRGILGDGSSITWDQLGEMSYTTMCIKETCRLIP 314

Query: 121 PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
            V  + R  +KP   P G T+  G+   V + ++GLH +  ++   + F P RF  +   
Sbjct: 315 AVPSISRDLSKPLTFPDGCTLPAGI--TVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSD 372

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R  + YLPF AG RNCIG  FAMI  K+ +  ++ +F+  V      P+ F     +LK
Sbjct: 373 QRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFR--VTPDPTRPLTFPNH-FILK 429

Query: 240 SAKGLWVRIE 249
              G+++ ++
Sbjct: 430 PKNGMYLHLK 439


>BC060857-1|AAH60857.1|  525|Homo sapiens cytochrome P450, family 4,
           subfamily V, polypeptide 2 protein.
          Length = 525

 Score =  114 bits (275), Expect = 2e-25
 Identities = 65/240 (27%), Positives = 135/240 (56%), Gaps = 15/240 (6%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           S++K+  FL +L+     E   N  +  +I  + DT       F+  G++T++  +++++
Sbjct: 292 SKNKRRAFLDLLLSVTDDEG--NRLSHEDIREEVDT-------FMFEGHDTTAAAINWSL 342

Query: 72  HVLATKPDLQETLRAHVQEM--TKGKEMSYELLAQMDYLEAFLQETLRIYPPVARVDRIC 129
           ++L + P++Q+ +   + ++     +  + E L ++ YLE  ++ETLR++P V    R  
Sbjct: 343 YLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSV 402

Query: 130 TKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPF 189
           ++   + G  V  G  +AV IP Y LH D   +P   EF+PERF  +  + R  + Y+PF
Sbjct: 403 SEDCEVAGYRVLKGT-EAVIIP-YALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPF 460

Query: 190 GAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIE 249
            AGPRNCIG +FA++  K  +  ++++F +   ++  + +  + + ++L+ + G+W++++
Sbjct: 461 SAGPRNCIGQKFAVMEEKTILSCILRHF-WIESNQKREELGLEGQ-LILRPSNGIWIKLK 518


>AY422002-1|AAR31180.1|  525|Homo sapiens cytochrome P450 4V2
           protein.
          Length = 525

 Score =  114 bits (275), Expect = 2e-25
 Identities = 65/240 (27%), Positives = 135/240 (56%), Gaps = 15/240 (6%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           S++K+  FL +L+     E   N  +  +I  + DT       F+  G++T++  +++++
Sbjct: 292 SKNKRRAFLDLLLSVTDDEG--NRLSHEDIREEVDT-------FMFEGHDTTAAAINWSL 342

Query: 72  HVLATKPDLQETLRAHVQEM--TKGKEMSYELLAQMDYLEAFLQETLRIYPPVARVDRIC 129
           ++L + P++Q+ +   + ++     +  + E L ++ YLE  ++ETLR++P V    R  
Sbjct: 343 YLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSV 402

Query: 130 TKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPF 189
           ++   + G  V  G  +AV IP Y LH D   +P   EF+PERF  +  + R  + Y+PF
Sbjct: 403 SEDCEVAGYRVLKGT-EAVIIP-YALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPF 460

Query: 190 GAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIE 249
            AGPRNCIG +FA++  K  +  ++++F +   ++  + +  + + ++L+ + G+W++++
Sbjct: 461 SAGPRNCIGQKFAVMEEKTILSCILRHF-WIESNQKREELGLEGQ-LILRPSNGIWIKLK 518


>AK126473-1|BAC86562.1|  503|Homo sapiens protein ( Homo sapiens
           cDNA FLJ44509 fis, clone UTERU3001585, weakly  similar
           to Cytochrome P450 4c3 (EC 1.14.-.-). ).
          Length = 503

 Score =  114 bits (275), Expect = 2e-25
 Identities = 65/240 (27%), Positives = 135/240 (56%), Gaps = 15/240 (6%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           S++K+  FL +L+     E   N  +  +I  + DT       F+  G++T++  +++++
Sbjct: 270 SKNKRRAFLDLLLSVTDDEG--NRLSHEDIREEVDT-------FMFEGHDTTAAAINWSL 320

Query: 72  HVLATKPDLQETLRAHVQEM--TKGKEMSYELLAQMDYLEAFLQETLRIYPPVARVDRIC 129
           ++L + P++Q+ +   + ++     +  + E L ++ YLE  ++ETLR++P V    R  
Sbjct: 321 YLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSV 380

Query: 130 TKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPF 189
           ++   + G  V  G  +AV IP Y LH D   +P   EF+PERF  +  + R  + Y+PF
Sbjct: 381 SEDCEVAGYRVLKGT-EAVIIP-YALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPF 438

Query: 190 GAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIE 249
            AGPRNCIG +FA++  K  +  ++++F +   ++  + +  + + ++L+ + G+W++++
Sbjct: 439 SAGPRNCIGQKFAVMEEKTILSCILRHF-WIESNQKREELGLEGQ-LILRPSNGIWIKLK 496


>AK122600-1|BAC85487.1|  525|Homo sapiens protein ( Homo sapiens
           cDNA FLJ16007 fis, clone KIDNE2006580, weakly  similar
           to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
          Length = 525

 Score =  114 bits (275), Expect = 2e-25
 Identities = 65/240 (27%), Positives = 135/240 (56%), Gaps = 15/240 (6%)

Query: 12  SESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAI 71
           S++K+  FL +L+     E   N  +  +I  + DT       F+  G++T++  +++++
Sbjct: 292 SKNKRRAFLDLLLSVTDDEG--NRLSHEDIREEVDT-------FMFEGHDTTAAAINWSL 342

Query: 72  HVLATKPDLQETLRAHVQEM--TKGKEMSYELLAQMDYLEAFLQETLRIYPPVARVDRIC 129
           ++L + P++Q+ +   + ++     +  + E L ++ YLE  ++ETLR++P V    R  
Sbjct: 343 YLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVIKETLRLFPSVPLFARSV 402

Query: 130 TKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPF 189
           ++   + G  V  G  +AV IP Y LH D   +P   EF+PERF  +  + R  + Y+PF
Sbjct: 403 SEDCEVAGYRVLKGT-EAVIIP-YALHRDPRYFPNPEEFQPERFFPENAQGRHPYAYVPF 460

Query: 190 GAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLKSAKGLWVRIE 249
            AGPRNCIG +FA++  K  +  ++++F +   ++  + +  + + ++L+ + G+W++++
Sbjct: 461 SAGPRNCIGQKFAVMEEKTILSCILRHF-WIESNQKREELGLEGQ-LILRPSNGIWIKLK 518


>S67580-1|AAB29502.1|  519|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 519

 Score =  112 bits (269), Expect = 1e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPIAR--LVLKSKNGIHLRL 506


>AY280371-1|AAQ21367.1|  519|Homo sapiens cytochrome P450 4A22K
           protein.
          Length = 519

 Score =  111 bits (268), Expect = 2e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRTPIPMAR--LVLKSKNGIHLRL 506


>AY280372-1|AAQ21368.1|  519|Homo sapiens cytochrome P450 4A22
           protein.
          Length = 519

 Score =  111 bits (267), Expect = 2e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPMAR--LVLKSKNGIHLRL 506


>AL135960-10|CAI19737.1|  519|Homo sapiens cytochrome P450, family
           4, subfamily A, polypeptide 22 protein.
          Length = 519

 Score =  111 bits (267), Expect = 2e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNLEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPMAR--LVLKSKNGIHLRL 506


>AF208532-1|AAF76722.1|  519|Homo sapiens fatty acid
           omega-hydroxylase CYP4A11 protein.
          Length = 519

 Score =  111 bits (267), Expect = 2e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNLEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPIAR--LVLKSKNGIHLRL 506


>L04751-1|AAA58436.1|  519|Homo sapiens cytochrome P450 protein.
          Length = 519

 Score =  111 bits (266), Expect = 3e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPIAR--LVLKSKNGIHLRL 506


>D26481-1|BAA05491.1|  519|Homo sapiens fatty acids
           omega-hydroxylase protein.
          Length = 519

 Score =  111 bits (266), Expect = 3e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPIAR--LVLKSKNGIHLRL 506


>AY369778-1|AAQ56847.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 519

 Score =  111 bits (266), Expect = 3e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPIAR--LVLKSKNGIHLRL 506


>AL731892-3|CAH72778.1|  519|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 519

 Score =  111 bits (266), Expect = 3e-24
 Identities = 66/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPIAR--LVLKSKNGIHLRL 506


>X16699-1|CAA34672.1|  511|Homo sapiens protein ( Human mRNA for
           cytochrome P-450HP. ).
          Length = 511

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 319 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 378

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 493

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 494 SKNGFHLHLK 503


>J02871-1|AAA35712.1|  511|Homo sapiens protein ( Human lung
           cytochrome P450 (IV subfamily) BI protein, complete cds.
           ).
          Length = 511

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 319 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 378

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 493

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 494 SKNGFHLHLK 503


>DQ518907-1|ABF47106.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 319 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 378

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 493

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 494 SKNGFHLHLK 503


>BC017758-1|AAH17758.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 320 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 379

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 380 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 438 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 494

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 495 SKNGFHLHLK 504


>AY151049-1|AAN72312.1|  497|Homo sapiens pulmonary cytochrome P450
           4B1 variant protein.
          Length = 497

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 304

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 305 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 364

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 365 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 422

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 423 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 479

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 480 SKNGFHLHLK 489


>AY151048-1|AAN72311.1|  512|Homo sapiens pulmonary cytochrome P450
           4B1 protein.
          Length = 512

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 320 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 379

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 380 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 438 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 494

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 495 SKNGFHLHLK 504


>AY064485-1|AAL57720.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 319 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 378

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 493

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 494 SKNGFHLHLK 503


>AL593856-7|CAI16983.1|  497|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 497

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 304

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 305 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 364

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 365 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 422

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 423 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 479

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 480 SKNGFHLHLK 489


>AL593856-6|CAI16982.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 320 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 379

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 380 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 438 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 494

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 495 SKNGFHLHLK 504


>AL593856-5|CAI16981.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 319 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 378

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 493

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 494 SKNGFHLHLK 503


>AL356793-4|CAI22559.1|  511|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 511

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 319 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 378

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 493

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 494 SKNGFHLHLK 503


>AL356793-3|CAI22557.1|  512|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 512

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 269 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 319

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 320 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 379

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 380 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 437

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 438 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 494

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 495 SKNGFHLHLK 504


>AL356793-2|CAI22558.1|  497|Homo sapiens cytochrome P450, family 4,
           subfamily B, polypeptide 1 protein.
          Length = 497

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 254 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 304

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 305 TTTSGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 364

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 365 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 422

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 423 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 479

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 480 SKNGFHLHLK 489


>AF491285-1|AAM09532.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score =  110 bits (264), Expect = 5e-24
 Identities = 69/250 (27%), Positives = 131/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T+++ +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 319 TTTSGISWFLYCIALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 378

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 493

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 494 SKNGFHLHLK 503


>AF525488-1|AAO16078.1|  519|Homo sapiens cytochrome P450, subfamily
           IVA, polypeptide 11 protein.
          Length = 519

 Score =  109 bits (262), Expect = 9e-24
 Identities = 65/209 (31%), Positives = 110/209 (52%), Gaps = 9/209 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR++PPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+ 
Sbjct: 423 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFEL 480

Query: 220 SVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
            +   T  PI   +  ++LKS  G+ +R+
Sbjct: 481 -LPDPTRIPIPIAR--LVLKSKNGIHLRL 506


>AY064486-1|AAL57721.1|  511|Homo sapiens cytochrome P450 protein.
          Length = 511

 Score =  109 bits (261), Expect = 1e-23
 Identities = 69/250 (27%), Positives = 130/250 (52%), Gaps = 16/250 (6%)

Query: 2   LQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYE 61
           LQ  K  ++    +  DFL IL+   A++       + +I L D  + A+   F+  G++
Sbjct: 268 LQDEKVRKKIQNRRHLDFLDILL--GARD-------EDDIKLSDADLRAEVDTFMFEGHD 318

Query: 62  TSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEM-SYELLAQMDYLEAFLQETLRIYP 120
           T++  +S+ ++ +A  P+ Q   R  V+E+   ++   ++ L +M YL   ++E+ R+YP
Sbjct: 319 TTTGGISWFLYCMALYPEHQHRCREEVREILGDQDFFQWDDLGKMTYLTMCIKESFRLYP 378

Query: 121 PVARVDRICTKPY-IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKK 179
           PV +V R  +KP   + G ++  G    +++ +Y LH +  ++P+   F   RF  +   
Sbjct: 379 PVPQVYRQLSKPVTFVDGRSLPAG--SLISMHIYALHRNSAVWPDPEVFDSLRFSTENAS 436

Query: 180 DRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVLLK 239
            R    ++PF AGPRNCIG +FAM   K+     +  F+FS+    + PI   +  ++L+
Sbjct: 437 KRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRL-PIKMPQ--LVLR 493

Query: 240 SAKGLWVRIE 249
           S  G  + ++
Sbjct: 494 SKNGFHLHLK 503


>D13705-1|BAA02864.1|  521|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 521

 Score =  108 bits (260), Expect = 2e-23
 Identities = 67/210 (31%), Positives = 111/210 (52%), Gaps = 10/210 (4%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 306 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 365

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 366 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 423

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVAL-MKNFK 218
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+   AL +  F+
Sbjct: 424 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVGQQALTLVRFE 481

Query: 219 FSVCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
             +   T  PI   +  ++LKS  G+ +R+
Sbjct: 482 L-LPDPTRIPIPIAR--LVLKSKNGIHLRL 508


>AF280110-1|AAG33011.1|  420|Homo sapiens cytochrome P450 subfamily
           IIIA polypeptide 43 protein.
          Length = 420

 Score =  108 bits (260), Expect = 2e-23
 Identities = 65/174 (37%), Positives = 99/174 (56%), Gaps = 11/174 (6%)

Query: 2   LQAAKAERRSSESK-KGDFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           ++  K  R   + K + DF Q +ID   +KET      K    L D  + AQS++ + A 
Sbjct: 253 IERMKESRLKDKQKHRVDFFQQMIDSQNSKET------KSHKALSDLELVAQSIIIIFAA 306

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRI 118
           Y+T+ST L F ++ LAT PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR+
Sbjct: 307 YDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRL 366

Query: 119 YPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPER 172
           +P V+RV R+C K   I G  V +  G AV +P+Y LH D   + E  +F PER
Sbjct: 367 FPVVSRVTRVCKKDIEING--VFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 418


>S67581-1|AAB29503.1|  591|Homo sapiens fatty acid omega-hydroxylase
           protein.
          Length = 591

 Score =  107 bits (257), Expect = 4e-23
 Identities = 58/179 (32%), Positives = 95/179 (53%), Gaps = 6/179 (3%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFK 218
            ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+
Sbjct: 423 KVWPNPEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFE 479


>BC100982-1|AAI00983.1|  280|Homo sapiens CYP3A43 protein protein.
          Length = 280

 Score =  107 bits (257), Expect = 4e-23
 Identities = 62/157 (39%), Positives = 92/157 (58%), Gaps = 10/157 (6%)

Query: 18  DFLQILIDFA-AKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLAT 76
           DF Q +ID   +KET      K    L D  + AQS++ + A Y+T+ST L F ++ LAT
Sbjct: 130 DFFQQIIDSQNSKET------KSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELAT 183

Query: 77  KPDLQETLRAHVQEMTKGKE-MSYELLAQMDYLEAFLQETLRIYPPVARVDRICTKPYII 135
            PD+Q+ L+  +  +   K  ++Y+ L QM+YL+  + ETLR++P V+RV R+C K   I
Sbjct: 184 HPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEI 243

Query: 136 PGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPER 172
            G  V +  G AV +P+Y LH D   + E  +F PER
Sbjct: 244 NG--VFIPKGLAVMVPIYALHHDPKYWTEPEKFCPER 278


>BC022539-1|AAH22539.1|  500|Homo sapiens cytochrome P450, family
           46, subfamily A, polypeptide 1 protein.
          Length = 500

 Score = 96.3 bits (229), Expect = 9e-20
 Identities = 55/177 (31%), Positives = 91/177 (51%), Gaps = 5/177 (2%)

Query: 44  DDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELL 102
           DD+ +    + F IAG+ETS+  L+F +  L+ +P++   L+A V E+   K  + +E L
Sbjct: 288 DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDL 347

Query: 103 AQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
            ++ YL   L+E+LR+YPP     R+  +  +I G  V V     +    Y +   +  +
Sbjct: 348 GRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDG--VRVPGNTPLLFSTYVMGRMDTYF 405

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            +   F P+RF     K  P   Y PF  G R+CIG +FA +  K+ M  L++  +F
Sbjct: 406 EDPLTFNPDRFGPGAPK--PRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEF 460


>AF094480-1|AAD41244.1|  500|Homo sapiens cholesterol 24-hydroxylase
           protein.
          Length = 500

 Score = 96.3 bits (229), Expect = 9e-20
 Identities = 55/177 (31%), Positives = 91/177 (51%), Gaps = 5/177 (2%)

Query: 44  DDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELL 102
           DD+ +    + F IAG+ETS+  L+F +  L+ +P++   L+A V E+   K  + +E L
Sbjct: 288 DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDL 347

Query: 103 AQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
            ++ YL   L+E+LR+YPP     R+  +  +I G  V V     +    Y +   +  +
Sbjct: 348 GRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDG--VRVPGNTPLLFSTYVMGRMDTYF 405

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            +   F P+RF     K  P   Y PF  G R+CIG +FA +  K+ M  L++  +F
Sbjct: 406 EDPLTFNPDRFGPGAPK--PRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEF 460


>BC039307-1|AAH39307.1|  372|Homo sapiens FLJ16008 protein protein.
          Length = 372

 Score = 91.1 bits (216), Expect = 3e-18
 Identities = 50/172 (29%), Positives = 98/172 (56%), Gaps = 4/172 (2%)

Query: 56  LIAGYETSSTLLSFAIHVLATKPDLQETL-RAHVQEMTKGKEMSYELLAQMDYLEAFLQE 114
           L+AG +T+S  LS+ +++LA  P++Q+T+ R  V+ + +    +   + ++  + A L+E
Sbjct: 178 LLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRALLKE 237

Query: 115 TLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFM 174
           TLR++P +    R+  +  +I G  +  G    +A+  Y     ++ +P A+EF+PER++
Sbjct: 238 TLRLFPVLPGNGRVTQEDLVIGGYLIPKGT--QLALCHYATSYQDENFPRAKEFRPERWL 295

Query: 175 DDQKKDRPSHL-YLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKT 225
                DR  +   +PFG G R+CIG R A +   + ++ L+++F+    S+T
Sbjct: 296 RKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQT 347


>BC032322-1|AAH32322.1|  509|Homo sapiens cytochrome P450, family
           51, subfamily A, polypeptide 1 protein.
          Length = 509

 Score = 90.2 bits (214), Expect = 6e-18
 Identities = 62/218 (28%), Positives = 106/218 (48%), Gaps = 17/218 (7%)

Query: 8   ERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLL 67
           +RR S+ K  D LQ L+D   K+            L DD +    +  L+AG  TSST  
Sbjct: 276 KRRQSQEKIDDILQTLLDATYKDGRP---------LTDDEVAGMLIGLLLAGQHTSSTTS 326

Query: 68  SFAIHVLATKPDLQETLRAHVQEMTKGKE----MSYELLAQMDYLEAFLQETLRIYPPVA 123
           ++    LA    LQ+  + ++++ T   E    ++Y+ L  ++ L+  ++ETLR+ PPV 
Sbjct: 327 AWMGFFLARDKTLQK--KCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPVM 384

Query: 124 RVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
            + R+   P  + G T+  G    V+ P     + +D + E  +F P+R++ D       
Sbjct: 385 IMMRMARTPQTVAGYTIPPGHQVCVS-PTVNQRL-KDSWVERLDFNPDRYLQDNPASGEK 442

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
             Y+PFGAG   CIG  FA +  K     +++ ++F +
Sbjct: 443 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDL 480


>AK131190-1|BAD18388.1|  372|Homo sapiens .-.-).  protein.
          Length = 372

 Score = 90.2 bits (214), Expect = 6e-18
 Identities = 50/172 (29%), Positives = 98/172 (56%), Gaps = 4/172 (2%)

Query: 56  LIAGYETSSTLLSFAIHVLATKPDLQETL-RAHVQEMTKGKEMSYELLAQMDYLEAFLQE 114
           L+AG +T+S  LS+ +++LA  P++Q+T+ R  V+ + +    +   + ++  + A L+E
Sbjct: 178 LLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAADVPKVPLVRALLKE 237

Query: 115 TLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFM 174
           TLR++P +    R+  +  +I G  +  G    +A+  Y     ++ +P A+EF+PER++
Sbjct: 238 TLRLFPVLPGNGRVTQEDLVIGGYLIPKGT--QLALCHYATSYQDENFPRAKEFRPERWL 295

Query: 175 DDQKKDRPSHL-YLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKT 225
                DR  +   +PFG G R+CIG R A +   + ++ L+++F+    S+T
Sbjct: 296 RKGDLDRVDNFGSIPFGHGVRSCIGRRIAELEIHLVVIQLLQHFEIKTSSQT 347


>U23942-1|AAB39951.1|  509|Homo sapiens lanosterol 14-demethylase
           cytochrome P450 protein.
          Length = 509

 Score = 89.8 bits (213), Expect = 8e-18
 Identities = 61/218 (27%), Positives = 106/218 (48%), Gaps = 17/218 (7%)

Query: 8   ERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLL 67
           +RR S+ K  D LQ L+D   K+            L DD +    +  L+AG  TSST  
Sbjct: 276 KRRQSQEKIDDILQTLLDATYKDGRP---------LTDDEVAGMLIGLLLAGQHTSSTTS 326

Query: 68  SFAIHVLATKPDLQETLRAHVQEMTKGKE----MSYELLAQMDYLEAFLQETLRIYPPVA 123
           ++    LA    LQ+  + ++++ T   E    ++Y+ L  ++ L+  ++ETLR+ PP+ 
Sbjct: 327 AWMGFFLARDKTLQK--KCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIM 384

Query: 124 RVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
            + R+   P  + G T+  G    V+ P     + +D + E  +F P+R++ D       
Sbjct: 385 IMMRMARTPQTVAGYTIPPGHQVCVS-PTVNQRL-KDSWVERLDFNPDRYLQDNPASGEK 442

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
             Y+PFGAG   CIG  FA +  K     +++ ++F +
Sbjct: 443 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDL 480


>D55653-1|BAA09512.1|  509|Homo sapiens lanosterol 14-demethylase
           protein.
          Length = 509

 Score = 89.8 bits (213), Expect = 8e-18
 Identities = 61/218 (27%), Positives = 106/218 (48%), Gaps = 17/218 (7%)

Query: 8   ERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLL 67
           +RR S+ K  D LQ L+D   K+            L DD +    +  L+AG  TSST  
Sbjct: 276 KRRQSQEKIDDILQTLLDATYKDGRP---------LTDDEVAGMLIGLLLAGQHTSSTTS 326

Query: 68  SFAIHVLATKPDLQETLRAHVQEMTKGKE----MSYELLAQMDYLEAFLQETLRIYPPVA 123
           ++    LA    LQ+  + ++++ T   E    ++Y+ L  ++ L+  ++ETLR+ PP+ 
Sbjct: 327 AWMGFFLARDKTLQK--KCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIM 384

Query: 124 RVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
            + R+   P  + G T+  G    V+ P     + +D + E  +F P+R++ D       
Sbjct: 385 IMMRMARTPQTVAGYTIPPGHQVCVS-PTVNQRL-KDSWVERLDFNPDRYLQDNPASGEK 442

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
             Y+PFGAG   CIG  FA +  K     +++ ++F +
Sbjct: 443 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDL 480


>AC000120-2|AAB46356.1|  509|Homo sapiens unknown protein.
          Length = 509

 Score = 89.8 bits (213), Expect = 8e-18
 Identities = 61/218 (27%), Positives = 106/218 (48%), Gaps = 17/218 (7%)

Query: 8   ERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLL 67
           +RR S+ K  D LQ L+D   K+            L DD +    +  L+AG  TSST  
Sbjct: 276 KRRQSQEKIDDILQTLLDATYKDGRP---------LTDDEVAGMLIGLLLAGQHTSSTTS 326

Query: 68  SFAIHVLATKPDLQETLRAHVQEMTKGKE----MSYELLAQMDYLEAFLQETLRIYPPVA 123
           ++    LA    LQ+  + ++++ T   E    ++Y+ L  ++ L+  ++ETLR+ PP+ 
Sbjct: 327 AWMGFFLARDKTLQK--KCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIM 384

Query: 124 RVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
            + R+   P  + G T+  G    V+ P     + +D + E  +F P+R++ D       
Sbjct: 385 IMMRMARTPQTVAGYTIPPGHQVCVS-PTVNQRL-KDSWVERLDFNPDRYLQDNPASGEK 442

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
             Y+PFGAG   CIG  FA +  K     +++ ++F +
Sbjct: 443 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDL 480


>X71480-1|CAA50586.1|  141|Homo sapiens cytochrome P450 protein.
          Length = 141

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 47/144 (32%), Positives = 77/144 (53%), Gaps = 6/144 (4%)

Query: 55  FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQ 113
           F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++  L QM Y    ++
Sbjct: 2   FMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWNHLDQMPYTTMCIK 61

Query: 114 ETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPER 172
           E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH +  ++P    F P R
Sbjct: 62  EALRLYPPVPGISRELSTPVTFPDGRSLPKGI--TVMLSIYGLHHNPKVWPNPEVFDPSR 119

Query: 173 FMDDQKKDRPSHLYLPFGAGPRNC 196
           F     +   SH +LPF  G RNC
Sbjct: 120 FAPGSAQH--SHAFLPFSGGSRNC 141


>AK090886-1|BAC03539.1|  337|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
           Homo sapiens cholesterol 24-hydroxylase mRNA. ).
          Length = 337

 Score = 89.4 bits (212), Expect = 1e-17
 Identities = 56/177 (31%), Positives = 92/177 (51%), Gaps = 15/177 (8%)

Query: 44  DDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKE-MSYELL 102
           DD+ +    + F IAG+ETS+  L+F +  L+ +P++   L+A V E+   K  + +E L
Sbjct: 135 DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDL 194

Query: 103 AQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
            ++ YL   L+E+LR+YPP     R+  +  +I G + +V +G           MD   +
Sbjct: 195 GRLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGFSTYV-MG----------RMDT-YF 242

Query: 163 PEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKF 219
            +   F P+RF     K  P   Y PF  G R+CIG +FA +  K+ M  L++  +F
Sbjct: 243 EDPLTFNPDRFGPGAPK--PRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEF 297


>U51692-1|AAC50951.1|  503|Homo sapiens lanosterol 14-alpha
           demethylase protein.
          Length = 503

 Score = 87.4 bits (207), Expect = 4e-17
 Identities = 60/218 (27%), Positives = 105/218 (48%), Gaps = 17/218 (7%)

Query: 8   ERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLL 67
           +R  S+ K  D LQ L+D   K+            L DD +    +  L+AG  TSST  
Sbjct: 270 KRTQSQEKIDDILQTLLDATYKDGRP---------LTDDEVAGMLIGLLLAGQHTSSTTS 320

Query: 68  SFAIHVLATKPDLQETLRAHVQEMTKGKE----MSYELLAQMDYLEAFLQETLRIYPPVA 123
           ++    LA    LQ+  + ++++ T   E    ++Y+ L  ++ L+  ++ETLR+ PP+ 
Sbjct: 321 AWMGFFLARDKTLQK--KCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIRETLRLRPPIM 378

Query: 124 RVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPS 183
            + R+   P  + G T+  G    V+ P     + +D + E  +F P+R++ D       
Sbjct: 379 IMMRMARTPQTVAGYTIPPGHQVCVS-PTVNQRL-KDSWVERLDFNPDRYLQDNPASGEK 436

Query: 184 HLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
             Y+PFGAG   CIG  FA +  K     +++ ++F +
Sbjct: 437 FAYVPFGAGRHRCIGENFAYVQIKTIWSTMLRLYEFDL 474


>AL135960-11|CAI19738.1|  455|Homo sapiens cytochrome P450, family
           4, subfamily A, polypeptide 22 protein.
          Length = 455

 Score = 86.2 bits (204), Expect = 1e-16
 Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 6/155 (3%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPR 194
            ++P    F P RF     +   SH +LPF  G R
Sbjct: 423 KVWPNLEVFDPSRFAPGSAQH--SHAFLPFSGGSR 455


>AL135960-9|CAI19736.1|  421|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 22 protein.
          Length = 421

 Score = 86.2 bits (204), Expect = 1e-16
 Identities = 51/148 (34%), Positives = 77/148 (52%), Gaps = 8/148 (5%)

Query: 102 LAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDED 160
           L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH +  
Sbjct: 268 LDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNPK 325

Query: 161 IYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFS 220
           ++P    F P RF     +   SH +LPF  G RNCIG +FAM   K+A    +  F+  
Sbjct: 326 VWPNLEVFDPSRFAPGSAQH--SHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFEL- 382

Query: 221 VCSKTMDPIDFDKRAVLLKSAKGLWVRI 248
           +   T  PI   +  ++LKS  G+ +R+
Sbjct: 383 LPDPTRIPIPMAR--LVLKSKNGIHLRL 408


>BC041158-1|AAH41158.1|  455|Homo sapiens CYP4A11 protein protein.
          Length = 455

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 6/155 (3%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPR 194
            ++P    F P RF     +   SH +LPF  G R
Sbjct: 423 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSR 455


>AL731892-4|CAH72779.1|  455|Homo sapiens cytochrome P450, family 4,
           subfamily A, polypeptide 11 protein.
          Length = 455

 Score = 85.8 bits (203), Expect = 1e-16
 Identities = 48/155 (30%), Positives = 81/155 (52%), Gaps = 6/155 (3%)

Query: 42  LLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYE 100
           +L D  + A+   F+  G++T+++ +S+ ++ LAT P  QE  R  +  +   G  +++ 
Sbjct: 305 ILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWN 364

Query: 101 LLAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDE 159
            L QM Y    ++E LR+YPPV  + R  + P   P G ++  G+   V + +YGLH + 
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGI--MVLLSIYGLHHNP 422

Query: 160 DIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPR 194
            ++P    F P RF     +   SH +LPF  G R
Sbjct: 423 KVWPNPEVFDPFRFAPGSAQH--SHAFLPFSGGSR 455


>AL358613-3|CAH72804.1|  428|Homo sapiens cytochrome P450, family
           26, subfamily A, polypeptide 1 protein.
          Length = 428

 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 59/215 (27%), Positives = 103/215 (47%), Gaps = 19/215 (8%)

Query: 10  RSSESKKG--DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLL 67
           R+SE+ +G  D LQ+LI+ + +   +         LD   +   S   L  G+ET+++  
Sbjct: 190 RASEAGQGCKDALQLLIEHSWERGER---------LDMQALKQSSTELLFGGHETTASAA 240

Query: 68  SFAIHVLATKPDLQETLRAHVQ------EMTKGKEMSYELLAQMDYLEAFLQETLRIYPP 121
           +  I  L   P + + +R  ++      +  +  ++  E+L Q+ Y+   ++ETLR+ PP
Sbjct: 241 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 300

Query: 122 VARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           V    R+  K + + G  +  G    V   +   H   +I+    EF P+RFM    +D 
Sbjct: 301 VPGGFRVALKTFELNGYQIPKGWN--VIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDA 358

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKN 216
               ++PFG G R+C+G  FA I  KI  V L ++
Sbjct: 359 SRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 393


>AL358613-2|CAH72803.1|  497|Homo sapiens cytochrome P450, family
           26, subfamily A, polypeptide 1 protein.
          Length = 497

 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 59/215 (27%), Positives = 103/215 (47%), Gaps = 19/215 (8%)

Query: 10  RSSESKKG--DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLL 67
           R+SE+ +G  D LQ+LI+ + +   +         LD   +   S   L  G+ET+++  
Sbjct: 259 RASEAGQGCKDALQLLIEHSWERGER---------LDMQALKQSSTELLFGGHETTASAA 309

Query: 68  SFAIHVLATKPDLQETLRAHVQ------EMTKGKEMSYELLAQMDYLEAFLQETLRIYPP 121
           +  I  L   P + + +R  ++      +  +  ++  E+L Q+ Y+   ++ETLR+ PP
Sbjct: 310 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 369

Query: 122 VARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           V    R+  K + + G  +  G    V   +   H   +I+    EF P+RFM    +D 
Sbjct: 370 VPGGFRVALKTFELNGYQIPKGWN--VIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDA 427

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKN 216
               ++PFG G R+C+G  FA I  KI  V L ++
Sbjct: 428 SRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462


>AF005418-1|AAB88881.1|  497|Homo sapiens retinoic acid hydroxylase
           protein.
          Length = 497

 Score = 82.6 bits (195), Expect = 1e-15
 Identities = 59/215 (27%), Positives = 103/215 (47%), Gaps = 19/215 (8%)

Query: 10  RSSESKKG--DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLL 67
           R+SE+ +G  D LQ+LI+ + +   +         LD   +   S   L  G+ET+++  
Sbjct: 259 RASEAGQGCKDALQLLIEHSWERGER---------LDMQALKQSSTELLFGGHETTASAA 309

Query: 68  SFAIHVLATKPDLQETLRAHVQ------EMTKGKEMSYELLAQMDYLEAFLQETLRIYPP 121
           +  I  L   P + + +R  ++      +  +  ++  E+L Q+ Y+   ++ETLR+ PP
Sbjct: 310 TSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVIKETLRLNPP 369

Query: 122 VARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           V    R+  K + + G  +  G    V   +   H   +I+    EF P+RFM    +D 
Sbjct: 370 VPGGFRVALKTFELNGYQIPKGWN--VIYSICDTHDVAEIFTNKEEFNPDRFMLPHPEDA 427

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKN 216
               ++PFG G R+C+G  FA I  KI  V L ++
Sbjct: 428 SRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462


>M80646-1|AAA60617.1|  460|Homo sapiens thromboxane synthase
           protein.
          Length = 460

 Score = 81.8 bits (193), Expect = 2e-15
 Identities = 50/131 (38%), Positives = 70/131 (53%), Gaps = 6/131 (4%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE---LL 102
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E   L 
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 103 AQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIY 162
             + YL+  + ETLR+YPP  R  R   +   + G  +  G    + + V  LH D + +
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGA--VLEMAVGALHHDPEHW 446

Query: 163 PEAREFKPERF 173
           P    F PER+
Sbjct: 447 PSPETFNPERY 457


>BC132767-1|AAI32768.1|  544|Homo sapiens cytochrome P450, family 2,
           subfamily U, polypeptide 1 protein.
          Length = 544

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 48/177 (27%), Positives = 94/177 (53%), Gaps = 8/177 (4%)

Query: 57  IAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQET 115
           IAG +T++  L + +  ++  PD+QE +   ++ +    +  S    AQM Y EA + E 
Sbjct: 351 IAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEV 410

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPER 172
            R  +  P+A +  + ++  ++ G T+  G    + +P ++ +H D  I+ +  +F P R
Sbjct: 411 QRLTVVVPLA-IPHMTSENTVLQGYTIPKGT---LILPNLWSVHRDPAIWEKPEDFYPNR 466

Query: 173 FMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPI 229
           F+DDQ +      ++PFG G R C+G + A +   +  V+LM++F F++   +  P+
Sbjct: 467 FLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPL 523


>AY343323-1|AAQ21380.1|  544|Homo sapiens cytochrome P450 protein.
          Length = 544

 Score = 79.8 bits (188), Expect = 9e-15
 Identities = 48/177 (27%), Positives = 94/177 (53%), Gaps = 8/177 (4%)

Query: 57  IAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQET 115
           IAG +T++  L + +  ++  PD+QE +   ++ +    +  S    AQM Y EA + E 
Sbjct: 351 IAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEV 410

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPER 172
            R  +  P+A +  + ++  ++ G T+  G    + +P ++ +H D  I+ +  +F P R
Sbjct: 411 QRLTVVVPLA-IPHMTSENTVLQGYTIPKGT---LILPNLWSVHRDPAIWEKPEDFYPNR 466

Query: 173 FMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPI 229
           F+DDQ +      ++PFG G R C+G + A +   +  V+LM++F F++   +  P+
Sbjct: 467 FLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPL 523


>AY288916-1|AAP31972.1|  508|Homo sapiens cytochrome P450, family
           27, subfamily B, polypeptide 1 protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>AF256213-1|AAG00416.1|  508|Homo sapiens 25- hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>AF246895-1|AAF64299.1|  508|Homo sapiens 25-hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>AF027152-1|AAC51854.1|  508|Homo sapiens P450 25-hydroxyvitamin D-1
           alpha hydroxylase protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>AF020192-1|AAC51853.1|  508|Homo sapiens 25-hydroxyvitamin
           D-1-alpha-hydroxylase protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>AB006987-1|BAA23418.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1-alpha-hydroxylase protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>AB005990-1|BAA22657.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1alpha-hydroxylase protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>AB005989-1|BAA22656.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1alpha-hydroxylase protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>AB005038-1|BAA23416.1|  508|Homo sapiens 25-hydroxyvitamin D3
           1-alpha-hydroxylase protein.
          Length = 508

 Score = 79.4 bits (187), Expect = 1e-14
 Identities = 55/186 (29%), Positives = 94/186 (50%), Gaps = 21/186 (11%)

Query: 46  DTIDAQSLL-----FLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE 100
           + + AQS+L      L+AG +T S  LS+A++ L+  P++Q  L + +         +Y 
Sbjct: 300 EELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYP 359

Query: 101 ---LLAQMDYLEAFLQETLRIYPPVARVDRICTKP-----YIIPGTTVHVGVGDAVAIPV 152
              +L+Q+  L+A ++E LR+YP V    R+  K      YIIP  T+       V +  
Sbjct: 360 SATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTL-------VTLCH 412

Query: 153 YGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVA 212
           Y    D   +PE   F+P R++ +     P    LPFG G R+C+G R A +  ++A+  
Sbjct: 413 YATSRDPAQFPEPNSFRPARWLGEGPTPHP-FASLPFGFGKRSCMGRRLAELELQMALAQ 471

Query: 213 LMKNFK 218
           ++ +F+
Sbjct: 472 ILTHFE 477


>Y07508-1|CAA68807.1|  503|Homo sapiens protein ( Human mRNA for
           aromatase P-450. ).
          Length = 503

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>X13589-1|CAA31929.1|  503|Homo sapiens protein ( Human mRNA for
           aromatase (estrogen synthetase). ).
          Length = 503

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>M30804-1|AAA35728.1|  503|Homo sapiens protein ( Human aromatase
           cytochrome P-450 gene, exon 10. ).
          Length = 503

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>M22246-1|AAA35557.1|  503|Homo sapiens protein ( Human aromatase
           mRNA, complete cds. ).
          Length = 503

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>M18856-1|AAA35556.1|  419|Homo sapiens protein ( Human aromatase
           (Aro1) mRNA, complete cds. ).
          Length = 419

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 173 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 224

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 225 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 284

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 285 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 337

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 338 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 374


>DQ118405-1|AAZ23558.1|  503|Homo sapiens cytochrome P450 subfamily
           19 subfamily A polypeptide 1 protein.
          Length = 503

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>BC107785-1|AAI07786.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>BC035959-1|AAH35959.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>AY957953-1|AAX44046.1|  503|Homo sapiens cytochrome P450, family
           19, subfamily A, polypeptide 1 protein.
          Length = 503

 Score = 78.2 bits (184), Expect = 3e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRRRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>S67623-1|AAB29308.1|  257|Homo sapiens 25-hydroxyvitamin D
           24-hydroxylase cytochrome P450 subunit protein.
          Length = 257

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 49/185 (26%), Positives = 95/185 (51%), Gaps = 6/185 (3%)

Query: 57  IAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSY-ELLAQMDYLEAFLQET 115
           +A  ET++  L + ++ L+  P +Q+ L   +Q +    ++   E L  M YL+A L+E+
Sbjct: 68  LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKES 127

Query: 116 LRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMD 175
           +R+ P V    R   K  ++    +  G    +   V G    ED + ++ +F+PER++ 
Sbjct: 128 MRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLG--SSEDNFEDSSQFRPERWLQ 185

Query: 176 DQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRA 235
           +++K  P   +LPFG G R CIG R A +   +A+  +++  K+ + +   +P++     
Sbjct: 186 EKEKINP-FAHLPFGVGKRMCIGRRLAELQLHLALCWIVR--KYDIQATDNEPVEMLHSG 242

Query: 236 VLLKS 240
            L+ S
Sbjct: 243 TLVPS 247


>L13286-1|AAA62379.1|  513|Homo sapiens 1,25-dihydroxyvitamin D3
           24-hydroxylase protein.
          Length = 513

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 49/185 (26%), Positives = 95/185 (51%), Gaps = 6/185 (3%)

Query: 57  IAGYETSSTLLSFAIHVLATKPDLQETLRAHVQE-MTKGKEMSYELLAQMDYLEAFLQET 115
           +A  ET++  L + ++ L+  P +Q+ L   +Q  + + +    E L  M YL+A L+E+
Sbjct: 324 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPREEDLRNMPYLKACLKES 383

Query: 116 LRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMD 175
           +R+ P V    R   K  ++    +  G    +   V G    ED + ++ +F+PER++ 
Sbjct: 384 MRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLG--SSEDNFEDSSQFRPERWLQ 441

Query: 176 DQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRA 235
           +++K  P   +LPFG G R CIG R A +   +A+  +++  K+ + +   +P++     
Sbjct: 442 EKEKINP-FAHLPFGVGKRMCIGRRLAELQLHLALCWIVR--KYDIQATDNEPVEMLHSG 498

Query: 236 VLLKS 240
            L+ S
Sbjct: 499 TLVPS 503


>AY858838-1|AAW50795.1|  372|Homo sapiens vitamin D 24-hydroxylase
           splice variant protein.
          Length = 372

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 49/185 (26%), Positives = 95/185 (51%), Gaps = 6/185 (3%)

Query: 57  IAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSY-ELLAQMDYLEAFLQET 115
           +A  ET++  L + ++ L+  P +Q+ L   +Q +    ++   E L  M YL+A L+E+
Sbjct: 183 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKES 242

Query: 116 LRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMD 175
           +R+ P V    R   K  ++    +  G    +   V G    ED + ++ +F+PER++ 
Sbjct: 243 MRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLG--SSEDNFEDSSQFRPERWLQ 300

Query: 176 DQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRA 235
           +++K  P   +LPFG G R CIG R A +   +A+  +++  K+ + +   +P++     
Sbjct: 301 EKEKINP-FAHLPFGVGKRMCIGRRLAELQLHLALCWIVR--KYDIQATDNEPVEMLHSG 357

Query: 236 VLLKS 240
            L+ S
Sbjct: 358 TLVPS 362


>AL138805-3|CAB91829.1|  514|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 514

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 49/185 (26%), Positives = 95/185 (51%), Gaps = 6/185 (3%)

Query: 57  IAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSY-ELLAQMDYLEAFLQET 115
           +A  ET++  L + ++ L+  P +Q+ L   +Q +    ++   E L  M YL+A L+E+
Sbjct: 325 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKES 384

Query: 116 LRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMD 175
           +R+ P V    R   K  ++    +  G    +   V G    ED + ++ +F+PER++ 
Sbjct: 385 MRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLG--SSEDNFEDSSQFRPERWLQ 442

Query: 176 DQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRA 235
           +++K  P   +LPFG G R CIG R A +   +A+  +++  K+ + +   +P++     
Sbjct: 443 EKEKINP-FAHLPFGVGKRMCIGRRLAELQLHLALCWIVR--KYDIQATDNEPVEMLHSG 499

Query: 236 VLLKS 240
            L+ S
Sbjct: 500 TLVPS 504


>AL138805-1|CAM27342.1|  372|Homo sapiens cytochrome P450, family
           24, subfamily A, polypeptide 1 protein.
          Length = 372

 Score = 77.8 bits (183), Expect = 3e-14
 Identities = 49/185 (26%), Positives = 95/185 (51%), Gaps = 6/185 (3%)

Query: 57  IAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSY-ELLAQMDYLEAFLQET 115
           +A  ET++  L + ++ L+  P +Q+ L   +Q +    ++   E L  M YL+A L+E+
Sbjct: 183 LAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPRAEDLRNMPYLKACLKES 242

Query: 116 LRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMD 175
           +R+ P V    R   K  ++    +  G    +   V G    ED + ++ +F+PER++ 
Sbjct: 243 MRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLG--SSEDNFEDSSQFRPERWLQ 300

Query: 176 DQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRA 235
           +++K  P   +LPFG G R CIG R A +   +A+  +++  K+ + +   +P++     
Sbjct: 301 EKEKINP-FAHLPFGVGKRMCIGRRLAELQLHLALCWIVR--KYDIQATDNEPVEMLHSG 357

Query: 236 VLLKS 240
            L+ S
Sbjct: 358 TLVPS 362


>X54741-1|CAA38539.1|  503|Homo sapiens aldosterone  synthase
           (P-450aldo) protein.
          Length = 503

 Score = 77.4 bits (182), Expect = 5e-14
 Identities = 45/173 (26%), Positives = 84/173 (48%), Gaps = 4/173 (2%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYELLAQ 104
           + I A S+       +T++  L   +  LA  PD+Q+ LR   +       E   +   +
Sbjct: 302 EAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTE 361

Query: 105 MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPE 164
           +  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  ++P 
Sbjct: 362 LPLLRAALKETLRLYPVGLFLERVVSSDLVLQN--YHIPAGTLVQVFLYSLGRNAALFPR 419

Query: 165 AREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
              + P+R++D +   R  H ++PFG G R C+G R A     + +  ++K+F
Sbjct: 420 PERYNPQRWLDIRGSGRNFH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF 471


>D13752-1|BAA02899.1|  503|Homo sapiens steroid 18-hydroxylase
           protein.
          Length = 503

 Score = 77.4 bits (182), Expect = 5e-14
 Identities = 45/173 (26%), Positives = 84/173 (48%), Gaps = 4/173 (2%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYELLAQ 104
           + I A S+       +T++  L   +  LA  PD+Q+ LR   +       E   +   +
Sbjct: 302 EAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEHPQKATTE 361

Query: 105 MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPE 164
           +  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  ++P 
Sbjct: 362 LPLLRAALKETLRLYPVGLFLERVVSSDLVLQN--YHIPAGTLVQVFLYSLGRNAALFPR 419

Query: 165 AREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
              + P+R++D +   R  H ++PFG G R C+G R A     + +  ++K+F
Sbjct: 420 PERYNPQRWLDIRGSGRNFH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHF 471


>M32881-1|AAA35741.1|  503|Homo sapiens protein ( Human steroid
           11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
           ).
          Length = 503

 Score = 77.0 bits (181), Expect = 6e-14
 Identities = 45/173 (26%), Positives = 83/173 (47%), Gaps = 4/173 (2%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYELLAQ 104
           + I A S+       +T++  L   +  LA  PD+Q+ LR   +       E   +   +
Sbjct: 302 EAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAASISEHPQKATTE 361

Query: 105 MDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPE 164
           +  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  ++P 
Sbjct: 362 LPLLRAALKETLRLYPVGLFLERVVSSDLVLQN--YHIPAGTLVQVFLYSLGRNAALFPR 419

Query: 165 AREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
              + P+R++D +   R  H ++PFG G R C+G R A     + +  ++K F
Sbjct: 420 PERYNPQRWLDIRGSGRNLH-HVPFGFGMRQCLGRRLAEAEMLLLLHHVLKRF 471


>M28420-1|AAA52141.1|  419|Homo sapiens cytochrome P-450 aromatase
           protein.
          Length = 419

 Score = 76.6 bits (180), Expect = 8e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 173 VLIAEKRCRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 224

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 225 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 284

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 285 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 337

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 338 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 374


>J04127-1|AAA52132.1|  503|Homo sapiens CYP19 protein.
          Length = 503

 Score = 76.6 bits (180), Expect = 8e-14
 Identities = 60/217 (27%), Positives = 105/217 (48%), Gaps = 15/217 (6%)

Query: 1   MLQAAKAERRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGY 60
           +L A K  R S+E K    L+  +DFA +       A++   L  + ++   L  LIA  
Sbjct: 257 VLIAEKRCRISTEEK----LEECMDFATELIL----AEKRGDLTRENVNQCILEMLIAAP 308

Query: 61  ETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAFLQETLRIYP 120
           +T S  L F + ++A  P+++E +   +Q +   +++  + + ++  +E F+ E++R  P
Sbjct: 309 DTMSVSLFFMLFLIAKHPNVEEAIIKEIQTVIGERDIKIDDIQKLKVMENFIYESMRYQP 368

Query: 121 PVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKD 180
            V  V R   +  +I G  V  G    + + +  +H  E  +P+  EF  E F     K+
Sbjct: 369 VVDLVMRKALEDDVIDGYPVKKGTN--IILNIGRMHRLE-FFPKPNEFTLENFA----KN 421

Query: 181 RPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P   + PFG GPR C G   AM+  K  +V L++ F
Sbjct: 422 VPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458


>AM183950-1|CAJ75804.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 76.6 bits (180), Expect = 8e-14
 Identities = 61/215 (28%), Positives = 102/215 (47%), Gaps = 13/215 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYPPVAR 124
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P V  
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 125 VDRICT-KPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDRP 182
               CT +P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R 
Sbjct: 362 ALPHCTTRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRA 418

Query: 183 SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
               L FG G R C+G   A +   + +  L++ F
Sbjct: 419 ----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>X59812-1|CAA42481.1|  530|Homo sapiens Vitamin D3 25-hydroxylase
           protein.
          Length = 530

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 50/175 (28%), Positives = 87/175 (49%), Gaps = 7/175 (4%)

Query: 56  LIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTK-GKEMSYELLAQMDYLEAFLQE 114
           L+AG +T+S  L++A++ L+  P++QE L   V  +   G+   ++  A M  L+A L+E
Sbjct: 332 LMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE 391

Query: 115 TLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFM 174
           TLR+YP V    RI  K   + G               Y +  D   + E   F+P R++
Sbjct: 392 TLRLYPVVPTNSRIIEKEIEVDGFLFPKNT--QFVFCHYVVSRDPTAFSEPESFQPHRWL 449

Query: 175 DDQKKDRP--SHLY--LPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKT 225
            + +   P   H +  +PFG G R C+G R A +  ++ +  L++ +K  +  +T
Sbjct: 450 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 504


>M62401-1|AAA52142.1|  531|Homo sapiens sterol 27-hydroxylase
           protein.
          Length = 531

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 50/175 (28%), Positives = 87/175 (49%), Gaps = 7/175 (4%)

Query: 56  LIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTK-GKEMSYELLAQMDYLEAFLQE 114
           L+AG +T+S  L++A++ L+  P++QE L   V  +   G+   ++  A M  L+A L+E
Sbjct: 333 LMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE 392

Query: 115 TLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFM 174
           TLR+YP V    RI  K   + G               Y +  D   + E   F+P R++
Sbjct: 393 TLRLYPVVPTNSRIIEKEIEVDGFLFPKNT--QFVFCHYVVSRDPTAFSEPESFQPHRWL 450

Query: 175 DDQKKDRP--SHLY--LPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKT 225
            + +   P   H +  +PFG G R C+G R A +  ++ +  L++ +K  +  +T
Sbjct: 451 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 505


>M26856-1|AAA52064.1|  495|Homo sapiens protein ( Human
           21-hydroxylase B gene, complete cds. ).
          Length = 495

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>M13936-1|AAA59695.1|  494|Homo sapiens CYP21P protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>BX679671-8|CAM26071.1|  464|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 464

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 212 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 271

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 272 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 331

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 332 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 387

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 388 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 419


>BX679671-7|CAM26070.1|  494|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>BC125182-1|AAI25183.1|  494|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>BC125181-1|AAI25182.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>BC051851-1|AAH51851.1|  531|Homo sapiens cytochrome P450, family
           27, subfamily A, polypeptide 1 protein.
          Length = 531

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 50/175 (28%), Positives = 87/175 (49%), Gaps = 7/175 (4%)

Query: 56  LIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTK-GKEMSYELLAQMDYLEAFLQE 114
           L+AG +T+S  L++A++ L+  P++QE L   V  +   G+   ++  A M  L+A L+E
Sbjct: 333 LMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE 392

Query: 115 TLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFM 174
           TLR+YP V    RI  K   + G               Y +  D   + E   F+P R++
Sbjct: 393 TLRLYPVVPTNSRIIEKEIEVDGFLFPKNT--QFVFCHYVVSRDPTAFSEPESFQPHRWL 450

Query: 175 DDQKKDRP--SHLY--LPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKT 225
            + +   P   H +  +PFG G R C+G R A +  ++ +  L++ +K  +  +T
Sbjct: 451 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 505


>BC040430-1|AAH40430.1|  531|Homo sapiens cytochrome P450, family
           27, subfamily A, polypeptide 1 protein.
          Length = 531

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 50/175 (28%), Positives = 87/175 (49%), Gaps = 7/175 (4%)

Query: 56  LIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTK-GKEMSYELLAQMDYLEAFLQE 114
           L+AG +T+S  L++A++ L+  P++QE L   V  +   G+   ++  A M  L+A L+E
Sbjct: 333 LMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE 392

Query: 115 TLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFM 174
           TLR+YP V    RI  K   + G               Y +  D   + E   F+P R++
Sbjct: 393 TLRLYPVVPTNSRIIEKEIEVDGFLFPKNT--QFVFCHYVVSRDPTAFSEPESFQPHRWL 450

Query: 175 DDQKKDRP--SHLY--LPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKT 225
            + +   P   H +  +PFG G R C+G R A +  ++ +  L++ +K  +  +T
Sbjct: 451 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 505


>AM183951-1|CAJ75805.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>AM183947-1|CAJ75801.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>AM183946-1|CAJ75800.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>AM183945-1|CAJ75799.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>AM086565-1|CAJ31104.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGTHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>AM086564-1|CAJ31103.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>AL929593-2|CAI41778.1|  465|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 465

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 213 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 272

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 273 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 332

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 333 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 388

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 389 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 420


>AL929593-1|CAI41779.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>AL662849-19|CAI17480.1|  465|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 465

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 213 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 272

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 273 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 332

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 333 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 388

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 389 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 420


>AL662849-18|CAI17479.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>AL645922-24|CAI41754.1|  495|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 495

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>AL645922-23|CAI41755.1|  465|Homo sapiens cytochrome P450, family
           21, subfamily A, polypeptide 2 protein.
          Length = 465

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 213 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 272

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 273 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 332

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 333 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 388

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 389 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 420


>AL049547-7|CAB89301.1|  495|Homo sapiens dJ34F7.3 (cytochrome P450,
           subfamily XXIA (steroid 21-hydroxylase, congenital a
           protein.
          Length = 495

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>AF077974-1|AAD45405.1|  403|Homo sapiens cytochrome P450
           21-hydroxylase protein.
          Length = 403

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 151 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 210

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 211 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 270

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 271 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 326

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 327 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 358


>AF019413-2|AAB67982.1|  495|Homo sapiens cytochrome P450
           21-hydroxylase protein.
          Length = 495

 Score = 76.2 bits (179), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>X58906-1|CAA41709.1|  495|Homo sapiens steroid 21-monooxygenase
           protein.
          Length = 495

 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>M28548-1|AAA52065.1|  495|Homo sapiens protein ( Human mutant
           21-hydroxylase B gene, complete cds. ).
          Length = 495

 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPTMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>M21550-1|AAA52063.1|  495|Homo sapiens CYP21 protein.
          Length = 495

 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 243 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHLHMAAVDLLIGGTETTANTLS 302

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 303 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 362

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 363 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 418

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 419 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 450


>AM183949-1|CAJ75803.1|  494|Homo sapiens steroid 21-hydroxylase,
           CYP21 protein.
          Length = 494

 Score = 75.8 bits (178), Expect = 1e-13
 Identities = 62/216 (28%), Positives = 104/216 (48%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLFHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>AK054616-1|BAB70774.1|  465|Homo sapiens protein ( Homo sapiens
           cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
           CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
          Length = 465

 Score = 75.4 bits (177), Expect = 2e-13
 Identities = 59/202 (29%), Positives = 98/202 (48%), Gaps = 15/202 (7%)

Query: 23  LIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQE 82
           ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS+A   L   P++Q+
Sbjct: 227 MMDYMLQGVAQPSMEEGSGQLQEGHVHMAAVDLLIGGTETTANTLSWAAVFLLHHPEIQQ 286

Query: 83  TLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PVARVDRICTKPYIIP 136
            L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+A   R  T+P  I 
Sbjct: 287 RLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRT-TRPSSIS 345

Query: 137 GTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRN 195
           G  +  G    V IP + G H+DE ++    EF P+RF++  K  R     L FG G R 
Sbjct: 346 GYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRA----LAFGCGARV 398

Query: 196 CIGLRFAMISAKIAMVALMKNF 217
           C+G   A +   + +  L++ F
Sbjct: 399 CLGEPLARLELFVVLTRLLQAF 420


>AY178622-1|AAO21126.1|  531|Homo sapiens steroid hydroxylase
           protein.
          Length = 531

 Score = 74.9 bits (176), Expect = 2e-13
 Identities = 49/175 (28%), Positives = 87/175 (49%), Gaps = 7/175 (4%)

Query: 56  LIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTK-GKEMSYELLAQMDYLEAFLQE 114
           L+AG +T+S  L++A++ L+  P++Q+ L   V  +   G+   ++  A M  L+A L+E
Sbjct: 333 LMAGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKE 392

Query: 115 TLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFM 174
           TLR+YP V    RI  K   + G               Y +  D   + E   F+P R++
Sbjct: 393 TLRLYPVVPTNSRIIEKEIEVDGFLFPKNT--QFVFCHYEVSRDPTAFSEPESFQPHRWL 450

Query: 175 DDQKKDRP--SHLY--LPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKT 225
            + +   P   H +  +PFG G R C+G R A +  ++ +  L++ +K  +  +T
Sbjct: 451 RNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPET 505


>AM183948-1|CAJ75802.1|  494|Homo sapiens steroid 21-hydroxylase
           protein.
          Length = 494

 Score = 74.1 bits (174), Expect = 4e-13
 Identities = 61/216 (28%), Positives = 103/216 (47%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G E ++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTENTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G R C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 449


>M32879-1|AAA52149.1|  503|Homo sapiens CYP11B1 protein.
          Length = 503

 Score = 73.7 bits (173), Expect = 6e-13
 Identities = 44/177 (24%), Positives = 84/177 (47%), Gaps = 4/177 (2%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYEL 101
           L  D I A S+       +T+   L   +  LA  P++Q+ LR   +       E   + 
Sbjct: 299 LSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKA 358

Query: 102 LAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDI 161
             ++  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  +
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN--YHIPAGTLVRVFLYSLGRNPAL 416

Query: 162 YPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFK 218
           +P    + P+R++D +   R +  ++PFG G R C+G R A     + +  ++K+ +
Sbjct: 417 FPRPERYNPQRWLDIRGSGR-NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472


>BC096287-1|AAH96287.1|  503|Homo sapiens cytochrome P450, family
           11, subfamily B, polypeptide 1 protein.
          Length = 503

 Score = 73.7 bits (173), Expect = 6e-13
 Identities = 44/177 (24%), Positives = 84/177 (47%), Gaps = 4/177 (2%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYEL 101
           L  D I A S+       +T+   L   +  LA  P++Q+ LR   +       E   + 
Sbjct: 299 LSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKA 358

Query: 102 LAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDI 161
             ++  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  +
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN--YHIPAGTLVRVFLYSLGRNPAL 416

Query: 162 YPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFK 218
           +P    + P+R++D +   R +  ++PFG G R C+G R A     + +  ++K+ +
Sbjct: 417 FPRPERYNPQRWLDIRGSGR-NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472


>BC096285-1|AAH96285.1|  574|Homo sapiens CYP11B1 protein protein.
          Length = 574

 Score = 73.7 bits (173), Expect = 6e-13
 Identities = 44/177 (24%), Positives = 84/177 (47%), Gaps = 4/177 (2%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYEL 101
           L  D I A S+       +T+   L   +  LA  P++Q+ LR   +       E   + 
Sbjct: 370 LSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKA 429

Query: 102 LAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDI 161
             ++  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  +
Sbjct: 430 TTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN--YHIPAGTLVRVFLYSLGRNPAL 487

Query: 162 YPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFK 218
           +P    + P+R++D +   R +  ++PFG G R C+G R A     + +  ++K+ +
Sbjct: 488 FPRPERYNPQRWLDIRGSGR-NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 543


>AF478474-1|AAL84813.1|  503|Homo sapiens mutated cytochrome
           P-450c11 protein protein.
          Length = 503

 Score = 73.7 bits (173), Expect = 6e-13
 Identities = 44/177 (24%), Positives = 84/177 (47%), Gaps = 4/177 (2%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYEL 101
           L  D I A S+       +T+   L   +  LA  P++Q+ LR   +       E   + 
Sbjct: 299 LSPDAIKANSMELTAGSMDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKA 358

Query: 102 LAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDI 161
             ++  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  +
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVASSDLVLQN--YHIPAGTLVRVFLYSLGRNPAL 416

Query: 162 YPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFK 218
           +P    + P+R++D +   R +  ++PFG G R C+G R A     + +  ++K+ +
Sbjct: 417 FPRPERYNPQRWLDIRGSGR-NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472


>X55764-1|CAA39290.1|  503|Homo sapiens protein ( Human mRNA for
           cytochrome P-450 (11 Beta). ).
          Length = 503

 Score = 73.3 bits (172), Expect = 7e-13
 Identities = 44/177 (24%), Positives = 84/177 (47%), Gaps = 4/177 (2%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYEL 101
           L  D I A S+       +T+   L   +  LA  P++Q+ LR   +       E   + 
Sbjct: 299 LSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKA 358

Query: 102 LAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDI 161
             ++  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  +
Sbjct: 359 TTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQN--YHIPAGTLVRVFLYSLGRNPAL 416

Query: 162 YPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFK 218
           +P    + P+R++D +   R +  ++PFG G R C+G R A     + +  ++K+ +
Sbjct: 417 FPRPERYNPQRWLDIRGSGR-NFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQ 472


>M12792-1|AAB59440.1|  494|Homo sapiens steroid 21-hydroxylase
           protein.
          Length = 494

 Score = 73.3 bits (172), Expect = 7e-13
 Identities = 61/216 (28%), Positives = 103/216 (47%), Gaps = 15/216 (6%)

Query: 9   RRSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLS 68
           R+  ES      + ++D+  +  AQ    +    L +  +   ++  LI G ET++  LS
Sbjct: 242 RQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLS 301

Query: 69  FAIHVLATKPDLQETLRAHVQ-EMTKGKEMS---YELLAQMDYLEAFLQETLRIYP--PV 122
           +A+  L   P++Q+ L+  +  E+  G   S   Y+  A++  L A + E LR+ P  P+
Sbjct: 302 WAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPL 361

Query: 123 ARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREFKPERFMDDQKKDR 181
           A   R  T+P  I G  +  G    V IP + G H+DE ++    EF P+RF++  K  R
Sbjct: 362 ALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSR 417

Query: 182 PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
                L FG G   C+G   A +   + +  L++ F
Sbjct: 418 A----LAFGCGAPVCLGEPLARLDLFVVLTRLLQAF 449


>BC067433-1|AAH67433.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 72.1 bits (169), Expect = 2e-12
 Identities = 51/203 (25%), Positives = 95/203 (46%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 276 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 333

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A ++E  R    V + +    T+  I  G  +  G    V +
Sbjct: 334 GPSRIPAIKDRQEMPYMDAVVREIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 390

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A +   + 
Sbjct: 391 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL 450

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 451 LCAILQHFNL---KPLVDPKDID 470


>J02843-1|AAA52155.1|  493|Homo sapiens protein ( Human cytochrome
           P450IIE1 (ethanol-inducible) gene, complete cds. ).
          Length = 493

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 276 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 333

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A + E  R    V + +    T+  I  G  +  G    V +
Sbjct: 334 GPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 390

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A +   + 
Sbjct: 391 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL 450

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 451 LCAILQHFNL---KPLVDPKDID 470


>J02625-1|AAA35743.1|  493|Homo sapiens protein ( Human cytochrome
           P-450j mRNA, complete cds. ).
          Length = 493

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 276 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 333

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A + E  R    V + +    T+  I  G  +  G    V +
Sbjct: 334 GPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 390

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A +   + 
Sbjct: 391 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL 450

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 451 LCAILQHFNL---KPLVDPKDID 470


>DQ515958-1|ABF47105.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 276 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 333

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A + E  R    V + +    T+  I  G  +  G    V +
Sbjct: 334 GPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 390

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A +   + 
Sbjct: 391 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL 450

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 451 LCAILQHFNL---KPLVDPKDID 470


>DQ149222-1|AAZ77710.1|  493|Homo sapiens cytochrome P450 2E1
           protein.
          Length = 493

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 276 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 333

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A + E  R    V + +    T+  I  G  +  G    V +
Sbjct: 334 GPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 390

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A +   + 
Sbjct: 391 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL 450

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 451 LCAILQHFNL---KPLVDPKDID 470


>AL161645-2|CAH70047.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 276 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 333

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A + E  R    V + +    T+  I  G  +  G    V +
Sbjct: 334 GPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 390

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A +   + 
Sbjct: 391 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL 450

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 451 LCAILQHFNL---KPLVDPKDID 470


>AF182276-1|AAF13601.1|  493|Homo sapiens cytochrome P450-2E1
           protein.
          Length = 493

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 276 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 333

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A + E  R    V + +    T+  I  G  +  G    V +
Sbjct: 334 GPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 390

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A +   + 
Sbjct: 391 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL 450

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 451 LCAILQHFNL---KPLVDPKDID 470


>AF084225-1|AAD13753.1|  462|Homo sapiens cytochrome P450 2E1
           protein.
          Length = 462

 Score = 71.7 bits (168), Expect = 2e-12
 Identities = 51/203 (25%), Positives = 94/203 (46%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 245 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 302

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A + E  R    V + +    T+  I  G  +  G    V +
Sbjct: 303 GPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 359

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A +   + 
Sbjct: 360 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLL 419

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 420 LCAILQHFNL---KPLVDPKDID 439


>BC104909-1|AAI04910.1|  501|Homo sapiens cytochrome P450, family 2,
           subfamily R, polypeptide 1 protein.
          Length = 501

 Score = 70.9 bits (166), Expect = 4e-12
 Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 5/210 (2%)

Query: 10  RSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSF 69
           ++S ++K    Q  +D    E  Q           ++ I +   L +IAG ET++ +L +
Sbjct: 263 KASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGEL-IIAGTETTTNVLRW 321

Query: 70  AIHVLATKPDLQETLRAHVQE-MTKGKEMSYELLAQMDYLEAFLQETLRIYPPVAR-VDR 127
           AI  +A  P++Q  ++  +   M    + S++   +M Y EA L E LR    V   +  
Sbjct: 322 AILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFH 381

Query: 128 ICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYL 187
             ++  ++ G ++  G    V   +Y +H DE  + +   F PERF+D           +
Sbjct: 382 ATSEDAVVRGYSIPKGT--TVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALV 439

Query: 188 PFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
           PF  G R+C+G   A +   +   AL++ F
Sbjct: 440 PFSLGRRHCLGEHLARMEMFLFFTALLQRF 469


>BC104907-1|AAI04908.1|  501|Homo sapiens cytochrome P450, family 2,
           subfamily R, polypeptide 1 protein.
          Length = 501

 Score = 70.9 bits (166), Expect = 4e-12
 Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 5/210 (2%)

Query: 10  RSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSF 69
           ++S ++K    Q  +D    E  Q           ++ I +   L +IAG ET++ +L +
Sbjct: 263 KASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGEL-IIAGTETTTNVLRW 321

Query: 70  AIHVLATKPDLQETLRAHVQE-MTKGKEMSYELLAQMDYLEAFLQETLRIYPPVAR-VDR 127
           AI  +A  P++Q  ++  +   M    + S++   +M Y EA L E LR    V   +  
Sbjct: 322 AILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFH 381

Query: 128 ICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYL 187
             ++  ++ G ++  G    V   +Y +H DE  + +   F PERF+D           +
Sbjct: 382 ATSEDAVVRGYSIPKGT--TVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALV 439

Query: 188 PFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
           PF  G R+C+G   A +   +   AL++ F
Sbjct: 440 PFSLGRRHCLGEHLARMEMFLFFTALLQRF 469


>BC067435-1|AAH67435.1|  493|Homo sapiens cytochrome P450, family 2,
           subfamily E, polypeptide 1 protein.
          Length = 493

 Score = 70.9 bits (166), Expect = 4e-12
 Identities = 51/203 (25%), Positives = 93/203 (45%), Gaps = 11/203 (5%)

Query: 33  QNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT 92
           +  +A+R   +D  T+    L F  AG ET+ST L + + +L   P+++E L   +  + 
Sbjct: 276 EKHSAERLYTMDGITVTVADLFF--AGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVI 333

Query: 93  KGKEM-SYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYIIPGTTVHVGVGDAVAI 150
               + + +   +M Y++A + E  R    V + +    T+  I  G  +  G    V +
Sbjct: 334 GPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGT---VVV 390

Query: 151 PVY-GLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIA 209
           P    +  D   +P+  +FKPE F+++  K + S  + PF  G R C G   A     + 
Sbjct: 391 PTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARTELFLL 450

Query: 210 MVALMKNFKFSVCSKTMDPIDFD 232
           + A++++F        +DP D D
Sbjct: 451 LCAILQHFNL---KPLVDPKDID 470


>AY323817-1|AAQ23114.1|  501|Homo sapiens cytochrome P450 2R1
           protein.
          Length = 501

 Score = 70.9 bits (166), Expect = 4e-12
 Identities = 53/210 (25%), Positives = 95/210 (45%), Gaps = 5/210 (2%)

Query: 10  RSSESKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSF 69
           ++S ++K    Q  +D    E  Q           ++ I +   L +IAG ET++ +L +
Sbjct: 263 KASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGEL-IIAGTETTTNVLRW 321

Query: 70  AIHVLATKPDLQETLRAHVQE-MTKGKEMSYELLAQMDYLEAFLQETLRIYPPVAR-VDR 127
           AI  +A  P++Q  ++  +   M    + S++   +M Y EA L E LR    V   +  
Sbjct: 322 AILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFH 381

Query: 128 ICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYL 187
             ++  ++ G ++  G    V   +Y +H DE  + +   F PERF+D           +
Sbjct: 382 ATSEDAVVRGYSIPKGT--TVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALV 439

Query: 188 PFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
           PF  G R+C+G   A +   +   AL++ F
Sbjct: 440 PFSLGRRHCLGEHLARMEMFLFFTALLQRF 469


>AJ563379-2|CAD91649.1|   84|Homo sapiens cytochrome P450 protein.
          Length = 84

 Score = 69.7 bits (163), Expect = 9e-12
 Identities = 30/77 (38%), Positives = 52/77 (67%), Gaps = 2/77 (2%)

Query: 177 QKKDR-PSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRA 235
           +KKD    ++Y PFG GPRNCIG+RFA+++ K+A++ +++NF F  C +T  P+  D + 
Sbjct: 3   KKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLDTQG 62

Query: 236 VLLKSAKGLWVRIELID 252
            LL+  K + ++++  D
Sbjct: 63  -LLQPEKPIVLKVDSRD 78


>X65962-1|CAA46778.1|  356|Homo sapiens cytochrome P-450 II C
           protein.
          Length = 356

 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 58/220 (26%), Positives = 99/220 (45%), Gaps = 21/220 (9%)

Query: 26  FAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLR 85
           F  K   + D  K E  +++  I A  LL   AG ET+ST L +A+ +L   P++   ++
Sbjct: 133 FLIKMEQEKDNQKSEFTIENLVITAADLLG--AGTETTSTTLRYALLLLLKHPEVTAKVQ 190

Query: 86  AHVQEMT-KGKEMSYELLAQMDYLEAFLQETLR---IYP---PVARVDRICTKPYIIP-G 137
             ++ +  + +    +    M Y +A + E  R   + P   P A    I  + Y+IP G
Sbjct: 191 EEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDIKFRNYLIPKG 250

Query: 138 TTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCI 197
           TT+   +          LH D   +P    F P  F+D+    + S+ ++PF AG R C+
Sbjct: 251 TTILTSLTSV-------LH-DNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICV 302

Query: 198 GLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDFDKRAVL 237
           G   A +   + +  +++NF        +DP D D   V+
Sbjct: 303 GEGLARMELFLFLTFILQNFNL---KSLIDPKDLDTTPVV 339


>M17252-1|AAA59985.1|  230|Homo sapiens CYP21 protein.
          Length = 230

 Score = 69.3 bits (162), Expect = 1e-11
 Identities = 54/169 (31%), Positives = 82/169 (48%), Gaps = 15/169 (8%)

Query: 56  LIAGYETSSTLLSFAI----HVLATKPDLQETLRAHVQEMTKGKEMSYELLAQMDYLEAF 111
           LI G ET++  LS+A+    H L  +  LQE L   +        + Y+  A++  L A 
Sbjct: 25  LIGGTETTANTLSWAVVFLLHHLEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLIAT 84

Query: 112 LQETLRIYP--PVARVDRICTKPYIIPGTTVHVGVGDAVAIP-VYGLHMDEDIYPEAREF 168
           + E LR+ P  P+A   R  T+P  I G  +  G    V IP + G H+DE ++    EF
Sbjct: 85  IAEVLRLRPVVPLALPHRT-TRPSSISGYDIPEGT---VIIPNLQGAHLDETVWERPHEF 140

Query: 169 KPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNF 217
            P+RF++  K  R     L FG G R C+G   A +   + +  L++ F
Sbjct: 141 WPDRFLEPGKNSRA----LAFGCGARVCLGEPLARLELFVVLTRLLQAF 185


>U37143-1|AAC50370.2|  502|Homo sapiens cytochrome P450
           monooxygenase CYP2J2 protein.
          Length = 502

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 57/205 (27%), Positives = 95/205 (46%), Gaps = 12/205 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           DF+   +   +K T    ++  E  L   T+D    LF  AG ET+ST L +A+  +A  
Sbjct: 276 DFIDAYLKEMSKHTGNPTSSFHEENLICSTLD----LFF-AGTETTSTTLRWALLYMALY 330

Query: 78  PDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYII 135
           P++QE ++A +  +  +G++ S      M Y  A + E  R+   +   V R  T    +
Sbjct: 331 PEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL 390

Query: 136 PGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDD-QKKDRPSHLYLPFGAGPR 194
            G   H+  G  +   +  LH D   +     F P+ F+++ Q K R +  ++PF  G R
Sbjct: 391 AG--YHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREA--FMPFSIGKR 446

Query: 195 NCIGLRFAMISAKIAMVALMKNFKF 219
            C+G + A     I   +LM+ F F
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKFTF 471


>BC032594-1|AAH32594.1|  502|Homo sapiens cytochrome P450, family 2,
           subfamily J, polypeptide 2 protein.
          Length = 502

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 57/205 (27%), Positives = 95/205 (46%), Gaps = 12/205 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           DF+   +   +K T    ++  E  L   T+D    LF  AG ET+ST L +A+  +A  
Sbjct: 276 DFIDAYLKEMSKHTGNPTSSFHEENLICSTLD----LFF-AGTETTSTTLRWALLYMALY 330

Query: 78  PDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYII 135
           P++QE ++A +  +  +G++ S      M Y  A + E  R+   +   V R  T    +
Sbjct: 331 PEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL 390

Query: 136 PGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDD-QKKDRPSHLYLPFGAGPR 194
            G   H+  G  +   +  LH D   +     F P+ F+++ Q K R +  ++PF  G R
Sbjct: 391 AG--YHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREA--FMPFSIGKR 446

Query: 195 NCIGLRFAMISAKIAMVALMKNFKF 219
            C+G + A     I   +LM+ F F
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKFTF 471


>AY426985-1|AAQ93356.1|  502|Homo sapiens cytochrome P450, family 2,
           subfamily J, polypeptide 2 protein.
          Length = 502

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 57/205 (27%), Positives = 95/205 (46%), Gaps = 12/205 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           DF+   +   +K T    ++  E  L   T+D    LF  AG ET+ST L +A+  +A  
Sbjct: 276 DFIDAYLKEMSKHTGNPTSSFHEENLICSTLD----LFF-AGTETTSTTLRWALLYMALY 330

Query: 78  PDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYII 135
           P++QE ++A +  +  +G++ S      M Y  A + E  R+   +   V R  T    +
Sbjct: 331 PEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL 390

Query: 136 PGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDD-QKKDRPSHLYLPFGAGPR 194
            G   H+  G  +   +  LH D   +     F P+ F+++ Q K R +  ++PF  G R
Sbjct: 391 AG--YHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREA--FMPFSIGKR 446

Query: 195 NCIGLRFAMISAKIAMVALMKNFKF 219
            C+G + A     I   +LM+ F F
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKFTF 471


>AF272142-1|AAM44456.1|  502|Homo sapiens cytochrome P450 protein.
          Length = 502

 Score = 68.5 bits (160), Expect = 2e-11
 Identities = 57/205 (27%), Positives = 95/205 (46%), Gaps = 12/205 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           DF+   +   +K T    ++  E  L   T+D    LF  AG ET+ST L +A+  +A  
Sbjct: 276 DFIDAYLKEMSKHTGNPTSSFHEENLICSTLD----LFF-AGTETTSTTLRWALLYMALY 330

Query: 78  PDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYII 135
           P++QE ++A +  +  +G++ S      M Y  A + E  R+   +   V R  T    +
Sbjct: 331 PEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL 390

Query: 136 PGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDD-QKKDRPSHLYLPFGAGPR 194
            G   H+  G  +   +  LH D   +     F P+ F+++ Q K R +  ++PF  G R
Sbjct: 391 AG--YHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREA--FMPFSIGKR 446

Query: 195 NCIGLRFAMISAKIAMVALMKNFKF 219
            C+G + A     I   +LM+ F F
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKFTF 471


>BC109205-1|AAI09206.1|  512|Homo sapiens cytochrome P450, family
           26, subfamily B, polypeptide 1 protein.
          Length = 512

 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 12/217 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           D L +LI+ ++KE  +  T +    L D T++     +      ++S ++    H    +
Sbjct: 265 DALDLLIE-SSKEHGKEMTMQE---LKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320

Query: 78  PDLQETLRAHVQEMTKG----KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRICTKPY 133
             L++ LRAH    + G      +  + L+ + YL+  ++E +R++ P++   R   + +
Sbjct: 321 K-LRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTF 379

Query: 134 IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHL-YLPFGAG 192
            + G    +  G +V   +   H    ++ +   F P+RF   + +D+     YLPFG G
Sbjct: 380 ELDG--FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGG 437

Query: 193 PRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPI 229
            R C+G   A +  K+  V L    +F + ++T   I
Sbjct: 438 VRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRI 474


>BC069443-1|AAH69443.1|  512|Homo sapiens cytochrome P450, family
           26, subfamily B, polypeptide 1 protein.
          Length = 512

 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 12/217 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           D L +LI+ ++KE  +  T +    L D T++     +      ++S ++    H    +
Sbjct: 265 DALDLLIE-SSKEHGKEMTMQE---LKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320

Query: 78  PDLQETLRAHVQEMTKG----KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRICTKPY 133
             L++ LRAH    + G      +  + L+ + YL+  ++E +R++ P++   R   + +
Sbjct: 321 K-LRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTF 379

Query: 134 IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHL-YLPFGAG 192
            + G    +  G +V   +   H    ++ +   F P+RF   + +D+     YLPFG G
Sbjct: 380 ELDG--FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGG 437

Query: 193 PRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPI 229
            R C+G   A +  K+  V L    +F + ++T   I
Sbjct: 438 VRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRI 474


>AF252297-1|AAF76003.1|  512|Homo sapiens cytochrome P450 retinoid
           metabolizing protein P450RAI-2 protein.
          Length = 512

 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 12/217 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           D L +LI+ ++KE  +  T +    L D T++     +      ++S ++    H    +
Sbjct: 265 DALDLLIE-SSKEHGKEMTMQE---LKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320

Query: 78  PDLQETLRAHVQEMTKG----KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRICTKPY 133
             L++ LRAH    + G      +  + L+ + YL+  ++E +R++ P++   R   + +
Sbjct: 321 K-LRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTF 379

Query: 134 IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHL-YLPFGAG 192
            + G    +  G +V   +   H    ++ +   F P+RF   + +D+     YLPFG G
Sbjct: 380 ELDG--FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGG 437

Query: 193 PRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPI 229
            R C+G   A +  K+  V L    +F + ++T   I
Sbjct: 438 VRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRI 474


>AC007002-1|AAY14690.1|  512|Homo sapiens unknown protein.
          Length = 512

 Score = 68.1 bits (159), Expect = 3e-11
 Identities = 50/217 (23%), Positives = 99/217 (45%), Gaps = 12/217 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           D L +LI+ ++KE  +  T +    L D T++     +      ++S ++    H    +
Sbjct: 265 DALDLLIE-SSKEHGKEMTMQE---LKDGTLELIFAAYATTASASTSLIMQLLKHPTVLE 320

Query: 78  PDLQETLRAHVQEMTKG----KEMSYELLAQMDYLEAFLQETLRIYPPVARVDRICTKPY 133
             L++ LRAH    + G      +  + L+ + YL+  ++E +R++ P++   R   + +
Sbjct: 321 K-LRDELRAHGILHSGGCPCEGTLRLDTLSGLRYLDCVIKEVMRLFTPISGGYRTVLQTF 379

Query: 134 IIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDDQKKDRPSHL-YLPFGAG 192
            + G    +  G +V   +   H    ++ +   F P+RF   + +D+     YLPFG G
Sbjct: 380 ELDG--FQIPKGWSVMYSIRDTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGG 437

Query: 193 PRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPI 229
            R C+G   A +  K+  V L    +F + ++T   I
Sbjct: 438 VRTCLGKHLAKLFLKVLAVELASTSRFELATRTFPRI 474


>M24667-1|AAA52148.1|  256|Homo sapiens steroid 11-beta-hydroxylase
           protein.
          Length = 256

 Score = 67.7 bits (158), Expect = 4e-11
 Identities = 41/161 (25%), Positives = 75/161 (46%), Gaps = 4/161 (2%)

Query: 43  LDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAH-VQEMTKGKEMSYEL 101
           L  D I A  +       + +   L   +  LA  P++Q+ LR   +       E   + 
Sbjct: 89  LSPDAIKANCMELTAGSVDRTVFPLLMTLFELARNPNVQQPLRQESLAPAASISEHPQKA 148

Query: 102 LAQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDI 161
             ++  L A L+ETLR+YP    ++R+ +   ++     H+  G  V + +Y L  +  +
Sbjct: 149 TTELPLLRAALKETLRLYPVGLILERVVSSDLVLQN--YHIPAGTLVRVFLYSLGRNPAL 206

Query: 162 YPEAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFA 202
           +P    + P+R++D +   R +  ++PFG G R C+G R A
Sbjct: 207 FPRPERYNPQRWLDIKGSGR-NFYHVPFGFGMRQCLGRRLA 246


>L36085-1|AAC01761.1|  441|Homo sapiens thromboxane A2 synthase
           protein.
          Length = 441

 Score = 67.7 bits (158), Expect = 4e-11
 Identities = 41/101 (40%), Positives = 56/101 (55%), Gaps = 4/101 (3%)

Query: 46  DTIDAQSLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYE---LL 102
           D I  Q+ +FLIAGYE  +  LSFA ++LAT PD QE L   V ++ K K M+ E   L 
Sbjct: 330 DEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREV-DVFKEKHMAPEFCSLE 388

Query: 103 AQMDYLEAFLQETLRIYPPVARVDRICTKPYIIPGTTVHVG 143
             + YL+  + ETLR+YPP  R  R   +   + G  +  G
Sbjct: 389 EGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAG 429


>BC067429-1|AAH67429.1|  516|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 2 protein.
          Length = 516

 Score = 67.3 bits (157), Expect = 5e-11
 Identities = 48/170 (28%), Positives = 88/170 (51%), Gaps = 9/170 (5%)

Query: 58  AGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYEL--LAQMDYLEAFLQET 115
           AG++T +T +S+++  L TKP++Q  ++  +  +  G+E    L    Q+ YLEAF+ ET
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVI-GRERRPRLSDRPQLPYLEAFILET 375

Query: 116 LRIYPPVA-RVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFM 174
            R  P +   +    T+   + G   ++     V +  + ++ D +++ +  EF+PERF+
Sbjct: 376 FRHSPFLPFTIPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433

Query: 175 --DDQKKDRP-SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
             D    ++P S   + FG G R CIG   A     + +  L++  +FSV
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483


>AB080265-1|BAB85489.1|  502|Homo sapiens cytochrome P450 2J2
           protein.
          Length = 502

 Score = 66.9 bits (156), Expect = 6e-11
 Identities = 56/205 (27%), Positives = 94/205 (45%), Gaps = 12/205 (5%)

Query: 18  DFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAGYETSSTLLSFAIHVLATK 77
           DF+   +   +K T    ++  E  L   T+D    LF  AG ET+ST L +A+  +A  
Sbjct: 276 DFIDAYLKEMSKHTGNPTSSFHEENLICSTLD----LFF-AGTETTSTTLRWALLYMALY 330

Query: 78  PDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLRIYPPV-ARVDRICTKPYII 135
           P++QE ++  +  +  +G++ S      M Y  A + E  R+   +   V R  T    +
Sbjct: 331 PEIQEKVQVEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL 390

Query: 136 PGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERFMDD-QKKDRPSHLYLPFGAGPR 194
            G   H+  G  +   +  LH D   +     F P+ F+++ Q K R +  ++PF  G R
Sbjct: 391 AG--YHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREA--FMPFSIGKR 446

Query: 195 NCIGLRFAMISAKIAMVALMKNFKF 219
            C+G + A     I   +LM+ F F
Sbjct: 447 ACLGEQLARTELFIFFTSLMQKFTF 471


>L07093-1|AAA36660.1|  468|Homo sapiens cytochrome P450 protein.
          Length = 468

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 60/246 (24%), Positives = 109/246 (44%), Gaps = 25/246 (10%)

Query: 1   MLQAAKAERRSSE-SKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           +L+  K  + S + +   DF+     F  K   +    + E  +++  I A  LL   AG
Sbjct: 222 ILEKVKEHQESMDINNPRDFIDC---FLIKMEKEKQNQQSEFTIENLVITAADLLG--AG 276

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLR- 117
            ET+ST L +A+ +L   P++   ++  ++ +  + +    +    M Y +A + E  R 
Sbjct: 277 TETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRY 336

Query: 118 --IYP---PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPE 171
             + P   P A    +  + Y+IP GTT+   +          LH D   +P    F P 
Sbjct: 337 IDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSV-------LH-DNKEFPNPEMFDPR 388

Query: 172 RFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDF 231
            F+D+    + S+ ++PF AG R C+G   A +   + +  +++NF        +DP D 
Sbjct: 389 HFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL---KSLIDPKDL 445

Query: 232 DKRAVL 237
           D   V+
Sbjct: 446 DTTPVV 451


>BC096256-1|AAH96256.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 6 protein.
          Length = 494

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 50/193 (25%), Positives = 93/193 (48%), Gaps = 17/193 (8%)

Query: 52  SLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEA 110
           +L   I G ET ST L +   +L   P+++  +   +  +  K ++  +E  A+M Y+EA
Sbjct: 295 TLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEA 354

Query: 111 FLQETLR---IYP-PVARVDRICTK--PYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYP 163
            + E  R   + P  +AR  +  TK   + +P GT V+  +G  +  P +        + 
Sbjct: 355 VIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSF--------FS 406

Query: 164 EAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCS 223
             ++F P+ F++++ + + S  ++PF  G RNC G   A +   +    +M+NF+    S
Sbjct: 407 NPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK-SS 465

Query: 224 KTMDPIDFDKRAV 236
           ++   ID   R V
Sbjct: 466 QSPKDIDVSPRHV 478


>AY796203-1|AAV41877.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 60/246 (24%), Positives = 109/246 (44%), Gaps = 25/246 (10%)

Query: 1   MLQAAKAERRSSE-SKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           +L+  K  + S + +   DF+     F  K   +    + E  +++  I A  LL   AG
Sbjct: 244 ILEKVKEHQESMDINNPRDFIDC---FLIKMEKEKQNQQSEFTIENLVITAADLLG--AG 298

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLR- 117
            ET+ST L +A+ +L   P++   ++  ++ +  + +    +    M Y +A + E  R 
Sbjct: 299 TETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRY 358

Query: 118 --IYP---PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPE 171
             + P   P A    +  + Y+IP GTT+   +          LH D   +P    F P 
Sbjct: 359 IDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSV-------LH-DNKEFPNPEMFDPR 410

Query: 172 RFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDF 231
            F+D+    + S+ ++PF AG R C+G   A +   + +  +++NF        +DP D 
Sbjct: 411 HFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL---KSLIDPKDL 467

Query: 232 DKRAVL 237
           D   V+
Sbjct: 468 DTTPVV 473


>AL583836-2|CAH74068.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 60/246 (24%), Positives = 109/246 (44%), Gaps = 25/246 (10%)

Query: 1   MLQAAKAERRSSE-SKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           +L+  K  + S + +   DF+     F  K   +    + E  +++  I A  LL   AG
Sbjct: 244 ILEKVKEHQESMDINNPRDFIDC---FLIKMEKEKQNQQSEFTIENLVITAADLLG--AG 298

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLR- 117
            ET+ST L +A+ +L   P++   ++  ++ +  + +    +    M Y +A + E  R 
Sbjct: 299 TETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRY 358

Query: 118 --IYP---PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPE 171
             + P   P A    +  + Y+IP GTT+   +          LH D   +P    F P 
Sbjct: 359 IDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSV-------LH-DNKEFPNPEMFDPR 410

Query: 172 RFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDF 231
            F+D+    + S+ ++PF AG R C+G   A +   + +  +++NF        +DP D 
Sbjct: 411 HFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL---KSLIDPKDL 467

Query: 232 DKRAVL 237
           D   V+
Sbjct: 468 DTTPVV 473


>AL133513-2|CAH73444.1|  490|Homo sapiens cytochrome P450, family 2,
           subfamily C, polypeptide 19 protein.
          Length = 490

 Score = 65.3 bits (152), Expect = 2e-10
 Identities = 60/246 (24%), Positives = 109/246 (44%), Gaps = 25/246 (10%)

Query: 1   MLQAAKAERRSSE-SKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           +L+  K  + S + +   DF+     F  K   +    + E  +++  I A  LL   AG
Sbjct: 244 ILEKVKEHQESMDINNPRDFIDC---FLIKMEKEKQNQQSEFTIENLVITAADLLG--AG 298

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLR- 117
            ET+ST L +A+ +L   P++   ++  ++ +  + +    +    M Y +A + E  R 
Sbjct: 299 TETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSPCMQDRGHMPYTDAVVHEVQRY 358

Query: 118 --IYP---PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPE 171
             + P   P A    +  + Y+IP GTT+   +          LH D   +P    F P 
Sbjct: 359 IDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSV-------LH-DNKEFPNPEMFDPR 410

Query: 172 RFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDF 231
            F+D+    + S+ ++PF AG R C+G   A +   + +  +++NF        +DP D 
Sbjct: 411 HFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL---KSLIDPKDL 467

Query: 232 DKRAVL 237
           D   V+
Sbjct: 468 DTTPVV 473


>Z00036-1|CAA77335.1|  515|Homo sapiens protein ( Human mRNA for
           cytochrome P-3-450. ).
          Length = 515

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 48/171 (28%), Positives = 88/171 (51%), Gaps = 11/171 (6%)

Query: 58  AGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYEL--LAQMDYLEAFLQET 115
           AG++T +T +S+++  L TKP++Q  ++  +  +  G+E    L    Q+ YLEAF+ ET
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVI-GRERRPRLSDRPQLPYLEAFILET 375

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERF 173
            R   + P   +    T+   + G   ++     V +  + ++ D +++ +  EF+PERF
Sbjct: 376 FRHSSFLPFT-IPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERF 432

Query: 174 M--DDQKKDRP-SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
           +  D    ++P S   + FG G R CIG   A     + +  L++  +FSV
Sbjct: 433 LTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483


>M61854-1|AAB59426.1|  490|Homo sapiens cytochrome protein.
          Length = 490

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 60/246 (24%), Positives = 109/246 (44%), Gaps = 25/246 (10%)

Query: 1   MLQAAKAERRSSE-SKKGDFLQILIDFAAKETAQNDTAKREILLDDDTIDAQSLLFLIAG 59
           +L+  K  + S + +   DF+     F  K   +    + E  +++  I A  LL   AG
Sbjct: 244 ILEKVKEHQESMDINNPRDFIDC---FLIKMEKEKQNQQSEFTIENLVITAADLLG--AG 298

Query: 60  YETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEAFLQETLR- 117
            ET+ST L +A+ +L   P++   ++  ++ +  + +    +    M Y +A + E  R 
Sbjct: 299 TETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGHMPYTDAVVHEVQRY 358

Query: 118 --IYP---PVARVDRICTKPYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPE 171
             + P   P A    +  + Y+IP GTT+   +          LH D   +P    F P 
Sbjct: 359 IDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSV-------LH-DNKEFPNPEMFDPR 410

Query: 172 RFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCSKTMDPIDF 231
            F+D+    + S+ ++PF AG R C+G   A +   + +  +++NF        +DP D 
Sbjct: 411 HFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNL---KSLIDPKDL 467

Query: 232 DKRAVL 237
           D   V+
Sbjct: 468 DTTPVV 473


>M55053-1|AAA52146.1|  515|Homo sapiens cytochrome P3-450 protein.
          Length = 515

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 48/171 (28%), Positives = 88/171 (51%), Gaps = 11/171 (6%)

Query: 58  AGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYEL--LAQMDYLEAFLQET 115
           AG++T +T +S+++  L TKP++Q  ++  +  +  G+E    L    Q+ YLEAF+ ET
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVI-GRERRPRLSDRPQLPYLEAFILET 375

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERF 173
            R   + P   +    T+   + G   ++     V +  + ++ D +++ +  EF+PERF
Sbjct: 376 FRHSSFLPFT-IPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERF 432

Query: 174 M--DDQKKDRP-SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
           +  D    ++P S   + FG G R CIG   A     + +  L++  +FSV
Sbjct: 433 LTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483


>M31667-1|AAA52163.1|  515|Homo sapiens CYP1A2 protein.
          Length = 515

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 48/171 (28%), Positives = 88/171 (51%), Gaps = 11/171 (6%)

Query: 58  AGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYEL--LAQMDYLEAFLQET 115
           AG++T +T +S+++  L TKP++Q  ++  +  +  G+E    L    Q+ YLEAF+ ET
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVI-GRERRPRLSDRPQLPYLEAFILET 375

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERF 173
            R   + P   +    T+   + G   ++     V +  + ++ D +++ +  EF+PERF
Sbjct: 376 FRHSSFLPFT-IPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERF 432

Query: 174 M--DDQKKDRP-SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
           +  D    ++P S   + FG G R CIG   A     + +  L++  +FSV
Sbjct: 433 LTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483


>L00389-1|AAA35738.1|  516|Homo sapiens protein ( Human cytochrome
           P-450 4 gene, exon 7, and three Alu repeats in the 3'
           flank. ).
          Length = 516

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 48/171 (28%), Positives = 88/171 (51%), Gaps = 11/171 (6%)

Query: 58  AGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYEL--LAQMDYLEAFLQET 115
           AG++T +T +S+++  L TKP++Q  ++  +  +  G+E    L    Q+ YLEAF+ ET
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVI-GRERRPRLSDRPQLPYLEAFILET 375

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERF 173
            R   + P   +    T+   + G   ++     V +  + ++ D +++ +  EF+PERF
Sbjct: 376 FRHSSFLPFT-IPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERF 432

Query: 174 M--DDQKKDRP-SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
           +  D    ++P S   + FG G R CIG   A     + +  L++  +FSV
Sbjct: 433 LTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483


>DQ022432-1|AAY26399.1|  516|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 2 protein.
          Length = 516

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 48/171 (28%), Positives = 88/171 (51%), Gaps = 11/171 (6%)

Query: 58  AGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYEL--LAQMDYLEAFLQET 115
           AG++T +T +S+++  L TKP++Q  ++  +  +  G+E    L    Q+ YLEAF+ ET
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVI-GRERRPRLSDRPQLPYLEAFILET 375

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERF 173
            R   + P   +    T+   + G   ++     V +  + ++ D +++ +  EF+PERF
Sbjct: 376 FRHSSFLPFT-IPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERF 432

Query: 174 M--DDQKKDRP-SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
           +  D    ++P S   + FG G R CIG   A     + +  L++  +FSV
Sbjct: 433 LTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483


>BC117165-1|AAI17166.1|  494|Homo sapiens cytochrome P450, family 2,
           subfamily A, polypeptide 7 protein.
          Length = 494

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 50/189 (26%), Positives = 89/189 (47%), Gaps = 19/189 (10%)

Query: 52  SLLFLIAGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMT-KGKEMSYELLAQMDYLEA 110
           +L   IAG ET ST L +   +L   P+++  +   +  +  K ++  +E  A+M Y+EA
Sbjct: 295 TLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEA 354

Query: 111 FLQETLR---IYP-PVARVDRICTK--PYIIP-GTTVHVGVGDAVAIPVYGLHMDEDIYP 163
            + E  R   + P  +AR  +  TK   + +P GT V   +G  +  P +        + 
Sbjct: 355 VIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSF--------FS 406

Query: 164 EAREFKPERFMDDQKKDRPSHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSVCS 223
             ++F P+ F+DD+ + + S  ++PF  G R C G   A +   +    +M+NF+     
Sbjct: 407 NPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTVMQNFRL---K 463

Query: 224 KTMDPIDFD 232
            +  P D D
Sbjct: 464 SSQSPKDID 472


>BC067428-1|AAH67428.1|  516|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 2 protein.
          Length = 516

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 48/171 (28%), Positives = 88/171 (51%), Gaps = 11/171 (6%)

Query: 58  AGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYEL--LAQMDYLEAFLQET 115
           AG++T +T +S+++  L TKP++Q  ++  +  +  G+E    L    Q+ YLEAF+ ET
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVI-GRERRPRLSDRPQLPYLEAFILET 375

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERF 173
            R   + P   +    T+   + G   ++     V +  + ++ D +++ +  EF+PERF
Sbjct: 376 FRHSSFLPFT-IPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERF 432

Query: 174 M--DDQKKDRP-SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
           +  D    ++P S   + FG G R CIG   A     + +  L++  +FSV
Sbjct: 433 LTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483


>BC067427-1|AAH67427.1|  516|Homo sapiens cytochrome P450, family 1,
           subfamily A, polypeptide 2 protein.
          Length = 516

 Score = 64.9 bits (151), Expect = 3e-10
 Identities = 48/171 (28%), Positives = 88/171 (51%), Gaps = 11/171 (6%)

Query: 58  AGYETSSTLLSFAIHVLATKPDLQETLRAHVQEMTKGKEMSYEL--LAQMDYLEAFLQET 115
           AG++T +T +S+++  L TKP++Q  ++  +  +  G+E    L    Q+ YLEAF+ ET
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVI-GRERRPRLSDRPQLPYLEAFILET 375

Query: 116 LR--IYPPVARVDRICTKPYIIPGTTVHVGVGDAVAIPVYGLHMDEDIYPEAREFKPERF 173
            R   + P   +    T+   + G   ++     V +  + ++ D +++ +  EF+PERF
Sbjct: 376 FRHSSFLPFT-IPHSTTRDTTLNG--FYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERF 432

Query: 174 M--DDQKKDRP-SHLYLPFGAGPRNCIGLRFAMISAKIAMVALMKNFKFSV 221
           +  D    ++P S   + FG G R CIG   A     + +  L++  +FSV
Sbjct: 433 LTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSV 483


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.322    0.137    0.391 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 33,223,550
Number of Sequences: 224733
Number of extensions: 1313972
Number of successful extensions: 3481
Number of sequences better than 10.0: 448
Number of HSP's better than 10.0 without gapping: 368
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 2536
Number of HSP's gapped (non-prelim): 450
length of query: 254
length of database: 73,234,838
effective HSP length: 88
effective length of query: 166
effective length of database: 53,458,334
effective search space: 8874083444
effective search space used: 8874083444
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 64 (29.9 bits)