Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005290-TA|BGIBMGA005290-PA|IPR001680|WD-40 repeat,
IPR011046|WD40-like
(278 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC052292-1|AAH52292.1| 326|Homo sapiens GBL protein protein. 343 6e-94
BC017119-1|AAH17119.1| 326|Homo sapiens G protein beta subunit-... 343 6e-94
BC001313-1|AAH01313.1| 326|Homo sapiens G protein beta subunit-... 343 6e-94
BC088354-1|AAH88354.1| 326|Homo sapiens G protein beta subunit-... 340 3e-93
AY223837-1|AAO73410.1| 260|Homo sapiens LST8 protein. 308 1e-83
BC020499-1|AAH20499.1| 327|Homo sapiens GBL protein protein. 299 9e-81
AF195883-1|AAF04308.1| 230|Homo sapiens G protein beta subunit ... 276 5e-74
AK022227-1|BAB13990.1| 217|Homo sapiens protein ( Homo sapiens ... 207 3e-53
AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit pro... 79 2e-14
CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein. 78 4e-14
BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80 (WD40-conta... 78 4e-14
BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat ... 78 4e-14
Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-bindin... 75 2e-13
U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain pr... 75 2e-13
M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein. 75 2e-13
BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide bind... 75 2e-13
BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein. 75 2e-13
BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide bind... 75 2e-13
BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide bind... 75 2e-13
AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide bind... 75 2e-13
AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide bind... 75 2e-13
AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-bind... 75 2e-13
X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRN... 74 6e-13
CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein. 74 6e-13
BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide bind... 74 6e-13
BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein. 74 6e-13
BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide bind... 74 6e-13
BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide bind... 74 6e-13
BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide bind... 74 6e-13
AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38 pro... 74 6e-13
AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide bind... 74 6e-13
AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide bind... 74 6e-13
AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide bind... 74 6e-13
BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69 pro... 73 8e-13
AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens ... 73 8e-13
AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein. 73 8e-13
BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein. 72 2e-12
AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens ... 72 2e-12
BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical... 72 3e-12
AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens ... 71 6e-12
AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa prot... 69 1e-11
U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p... 69 2e-11
BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processin... 69 2e-11
BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processin... 69 2e-11
AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6 snRNP-spec... 69 2e-11
AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processin... 69 2e-11
AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processin... 69 2e-11
AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear rib... 69 2e-11
AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant p... 69 2e-11
BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide bind... 68 3e-11
AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide bind... 68 3e-11
Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats c... 68 4e-11
CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein. 68 4e-11
BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat ... 68 4e-11
AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat... 68 4e-11
AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat... 68 4e-11
AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat ... 68 4e-11
AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat ... 68 4e-11
AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat ... 68 4e-11
AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat ... 68 4e-11
AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A pro... 68 4e-11
AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-Ika... 68 4e-11
M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transduci... 66 1e-10
M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein. 66 1e-10
CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein. 66 1e-10
BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide bind... 66 1e-10
BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide bind... 66 1e-10
BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide bind... 66 1e-10
AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide bind... 66 1e-10
AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein. 66 1e-10
AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD rep... 65 3e-10
AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein. 65 3e-10
BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like ... 64 4e-10
BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like ... 64 4e-10
BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein. 64 4e-10
AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymeras... 64 4e-10
AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1 ... 64 4e-10
AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1 ... 64 4e-10
AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1 ... 64 4e-10
AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor ... 64 4e-10
BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5 prot... 63 9e-10
BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5 prot... 63 9e-10
AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens ... 63 9e-10
AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein pr... 63 9e-10
AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription ... 63 1e-09
Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1 ... 62 2e-09
BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like ... 62 2e-09
BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein. 62 2e-09
BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat dom... 62 2e-09
AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b pro... 62 2e-09
AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X... 62 2e-09
AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats pr... 62 2e-09
AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats pr... 62 2e-09
AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats pr... 62 2e-09
AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein. 62 2e-09
X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein. 62 3e-09
U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100 pr... 62 3e-09
U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor pro... 62 3e-09
CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein. 62 3e-09
BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,... 62 3e-09
BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B pro... 62 3e-09
AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,... 62 3e-09
AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiatio... 62 3e-09
BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1 (Dr... 61 4e-09
BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein. 61 4e-09
AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens ... 61 4e-09
M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human signal-tr... 61 5e-09
U72342-1|AAC51111.1| 410|Homo sapiens platelet activating facto... 60 1e-08
M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transduci... 60 1e-08
L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencepha... 60 1e-08
L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencepha... 60 1e-08
BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating fac... 60 1e-08
BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61 pro... 60 1e-08
AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens ... 60 1e-08
AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating fac... 60 1e-08
AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination p... 60 1e-08
AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker lissencep... 60 1e-08
AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta subunit-... 60 1e-08
AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog ... 60 1e-08
CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein. 59 1e-08
AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1 i... 59 1e-08
BC025392-1|AAH25392.1| 620|Homo sapiens WD repeat domain 16 pro... 59 2e-08
BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS box-... 59 2e-08
AK094847-1|BAC04435.1| 630|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK074435-1|BAB85083.1| 412|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein. 59 2e-08
AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein. 59 2e-08
AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD ... 59 2e-08
AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein. 59 2e-08
AB065281-1|BAB83743.1| 620|Homo sapiens WDR16 protein. 59 2e-08
BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like ... 58 3e-08
BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS box-... 58 3e-08
BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide bind... 58 3e-08
AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide bind... 58 3e-08
AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor co-rep... 58 3e-08
AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide bind... 58 3e-08
AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD pr... 58 3e-08
AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein. 58 3e-08
AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subuni... 58 3e-08
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 58 3e-08
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 58 3e-08
AK093494-1|BAC04184.1| 476|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease acti... 58 3e-08
AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating fac... 58 3e-08
AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease acti... 58 3e-08
AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease acti... 58 3e-08
AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease acti... 58 3e-08
AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease acti... 58 3e-08
AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease acti... 58 3e-08
AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease acti... 58 3e-08
AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease acti... 58 3e-08
AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease acti... 58 3e-08
AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease acti... 58 3e-08
AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease acti... 58 3e-08
AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein. 58 3e-08
BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein. 58 4e-08
BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A pr... 58 4e-08
BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein. 58 4e-08
BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein. 58 4e-08
BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein. 58 4e-08
AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens ... 58 4e-08
AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease acti... 58 4e-08
AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein. 58 4e-08
BC032551-1|AAH32551.1| 795|Homo sapiens phospholipase A2-activa... 57 6e-08
AL356133-3|CAH72641.1| 738|Homo sapiens phospholipase A2-activa... 57 6e-08
AK223544-1|BAD97264.1| 748|Homo sapiens Hypothetical protein DK... 57 6e-08
AK002143-1|BAA92105.1| 544|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AK001642-1|BAA91803.1| 795|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AJ238243-1|CAB42881.1| 738|Homo sapiens phospholipase A2 activa... 57 6e-08
AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kD... 57 6e-08
AF083395-1|AAD03030.1| 738|Homo sapiens phospholipase A2-activa... 57 6e-08
EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein. 57 8e-08
BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5... 57 8e-08
AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5... 57 8e-08
EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein. 56 1e-07
BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec... 56 1e-07
BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec... 56 1e-07
AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec... 56 1e-07
AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AF240696-1|AAF82746.1| 275|Homo sapiens WSB1 isoform 2 protein. 56 1e-07
EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein. 56 1e-07
BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B pr... 56 1e-07
AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AF145020-1|AAD42075.1| 649|Homo sapiens phospholipase A2 activa... 55 2e-07
BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein. 55 3e-07
BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein. 55 3e-07
AJ005821-1|CAA06718.2| 3027|Homo sapiens X-like 1 protein protein. 54 6e-07
AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker lissencep... 54 6e-07
AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta subunit-... 54 7e-07
DQ641253-1|ABG23317.1| 730|Homo sapiens CDW1 protein. 53 1e-06
BC033540-1|AAH33540.1| 730|Homo sapiens denticleless homolog (D... 53 1e-06
BC033297-1|AAH33297.1| 730|Homo sapiens denticleless homolog (D... 53 1e-06
AL606468-1|CAH70697.1| 730|Homo sapiens denticleless homolog (D... 53 1e-06
AL592297-1|CAH73803.1| 730|Homo sapiens denticleless homolog (D... 53 1e-06
AK000742-1|BAA91355.1| 730|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AF345896-1|AAK54706.1| 730|Homo sapiens RA-regulated nuclear ma... 53 1e-06
AF195765-1|AAF35182.1| 730|Homo sapiens L2DTL protein protein. 53 1e-06
AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal tra... 52 2e-06
AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens ... 52 3e-06
AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor p... 52 3e-06
AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3 ... 50 7e-06
AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide bin... 50 1e-05
AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease acti... 50 1e-05
M99438-1|AAA61194.1| 772|Homo sapiens transducin-like enhancer ... 49 2e-05
M99436-1|AAA61193.1| 743|Homo sapiens transducin-like enhancer ... 49 2e-05
EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related... 49 2e-05
EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related... 49 2e-05
BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein. 49 2e-05
BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein. 49 2e-05
BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 49 2e-05
BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 49 2e-05
BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 49 2e-05
AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein. 49 2e-05
AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 prot... 49 2e-05
AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AK026330-1|BAB15448.1| 173|Homo sapiens protein ( Homo sapiens ... 49 2e-05
AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein ... 49 2e-05
AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3 ... 49 2e-05
AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein. 49 2e-05
M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.... 48 3e-05
L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencepha... 48 3e-05
CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein. 48 3e-05
CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein. 48 3e-05
BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein. 48 3e-05
BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein. 48 3e-05
BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC022050-1|AAH22050.1| 551|Homo sapiens DMXL2 protein protein. 48 3e-05
BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide bind... 48 3e-05
AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repe... 48 3e-05
AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repe... 48 3e-05
AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7 ... 48 3e-05
AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repe... 48 3e-05
AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repe... 48 3e-05
AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repe... 48 3e-05
AF389880-1|AAL93215.1| 3036|Homo sapiens rabconnectin protein. 48 3e-05
AB020663-1|BAA74879.2| 2237|Homo sapiens KIAA0856 protein protein. 48 3e-05
BC021905-1|AAH21905.1| 896|Homo sapiens Unknown (protein for IM... 48 4e-05
AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( Human DNA seq... 48 4e-05
AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA seq... 48 4e-05
AK057039-1|BAB71353.1| 912|Homo sapiens protein ( Homo sapiens ... 48 4e-05
AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11 pro... 48 4e-05
BC063041-1|AAH63041.1| 1129|Homo sapiens WD repeat and HMG-box D... 48 5e-05
BC043349-1|AAH43349.1| 612|Homo sapiens WDHD1 protein protein. 48 5e-05
BC036713-1|AAH36713.1| 542|Homo sapiens ATG16L2 protein protein. 48 5e-05
BC017364-1|AAH17364.1| 743|Homo sapiens transducin-like enhance... 48 5e-05
BC005040-1|AAH05040.1| 613|Homo sapiens Unknown (protein for IM... 48 5e-05
BC000622-1|AAH00622.1| 613|Homo sapiens WDHD1 protein protein. 48 5e-05
AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide bind... 48 5e-05
AK093017-1|BAC04021.1| 619|Homo sapiens protein ( Homo sapiens ... 48 5e-05
AJ006266-1|CAA06932.1| 1129|Homo sapiens AND-1 protein protein. 48 5e-05
AC007766-2|AAD38075.1| 553|Homo sapiens TLE2_HUMAN [AA 191- 743... 48 5e-05
U97018-1|AAB57824.1| 717|Homo sapiens HuEMAP protein. 47 6e-05
U63810-1|AAC24948.1| 339|Homo sapiens WD40 protein Ciao 1 protein. 47 6e-05
EF011618-1|ABK41108.1| 339|Homo sapiens CDW8/WDR39 protein. 47 6e-05
CR456802-1|CAG33083.1| 339|Homo sapiens CIAO1 protein. 47 6e-05
BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1... 47 6e-05
BC033043-1|AAH33043.1| 815|Homo sapiens echinoderm microtubule ... 47 6e-05
BC032812-1|AAH32812.1| 339|Homo sapiens cytosolic iron-sulfur p... 47 6e-05
BC032541-1|AAH32541.1| 815|Homo sapiens echinoderm microtubule ... 47 6e-05
BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein. 47 6e-05
BC001395-1|AAH01395.1| 339|Homo sapiens cytosolic iron-sulfur p... 47 6e-05
AK223257-1|BAD96977.1| 339|Homo sapiens WD40 protein Ciao1 vari... 47 6e-05
AJ420603-1|CAD12600.2| 815|Homo sapiens echinoderm microtubule ... 47 6e-05
AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1... 47 6e-05
AC004020-1|AAC23493.1| 339|Homo sapiens Unknown gene product pr... 47 6e-05
AB209201-1|BAD92438.1| 466|Homo sapiens WD repeat-containing pr... 47 6e-05
BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat dom... 47 8e-05
BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat dom... 47 8e-05
BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein. 47 8e-05
AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 prot... 47 8e-05
AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 prot... 47 8e-05
AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 pro... 47 8e-05
AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isof... 47 8e-05
AK090597-1|BAC03485.1| 513|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens ... 47 8e-05
AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form p... 47 8e-05
AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form ... 47 8e-05
AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 pro... 47 8e-05
AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isof... 47 8e-05
U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated pro... 46 1e-04
BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated p... 46 1e-04
AB209669-1|BAD92906.1| 1903|Homo sapiens Telomerase protein comp... 46 1e-04
BC068485-1|AAH68485.1| 383|Homo sapiens WD repeat domain 55 pro... 45 3e-04
AK025355-1|BAB15118.1| 383|Homo sapiens protein ( Homo sapiens ... 45 3e-04
AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein. 45 3e-04
AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein. 45 3e-04
X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein. 45 3e-04
U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan prote... 45 3e-04
U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan prote... 45 3e-04
U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein. 45 3e-04
M99439-1|AAA61195.1| 448|Homo sapiens transducin-like enhancer ... 45 3e-04
BC059405-1|AAH59405.2| 805|Homo sapiens TLE4 protein protein. 45 3e-04
BC045650-1|AAH45650.1| 704|Homo sapiens TLE4 protein protein. 45 3e-04
BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptopha... 45 3e-04
BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptopha... 45 3e-04
BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated prote... 45 3e-04
AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan pro... 45 3e-04
AL445252-3|CAI13644.1| 764|Homo sapiens transducin-like enhance... 45 3e-04
AL358975-3|CAI13734.1| 764|Homo sapiens transducin-like enhance... 45 3e-04
AL353813-5|CAI41315.1| 764|Homo sapiens transducin-like enhance... 45 3e-04
AL163279-2|CAB90452.1| 2295|Homo sapiens homolog to cAMP respons... 45 3e-04
AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated prote... 45 3e-04
AJ292466-1|CAC44372.1| 2269|Homo sapiens WDR9 protein, form B p... 45 3e-04
AJ292465-1|CAC44371.1| 2320|Homo sapiens WDR9 protein, form A pr... 45 3e-04
AJ238214-1|CAC37033.2| 2269|Homo sapiens hypothetical protein pr... 45 3e-04
AB080587-1|BAD74072.1| 2199|Homo sapiens WD repeat protein WDR9-... 45 3e-04
AB080586-1|BAD74071.1| 2269|Homo sapiens WD repeat protein protein. 45 3e-04
AB033087-1|BAA86575.1| 787|Homo sapiens KIAA1261 protein protein. 45 3e-04
AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein. 45 3e-04
X96586-1|CAA65405.1| 917|Homo sapiens FAN protein protein. 44 4e-04
AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing ... 44 4e-04
AK131467-1|BAD18612.1| 419|Homo sapiens protein ( Homo sapiens ... 44 4e-04
M99435-1|AAA61192.1| 770|Homo sapiens transducin-like enhancer ... 44 6e-04
BC041124-1|AAH41124.1| 917|Homo sapiens neutral sphingomyelinas... 44 6e-04
BC029520-1|AAH29520.1| 384|Homo sapiens WDSUB1 protein protein. 44 6e-04
BC015747-1|AAH15747.1| 770|Homo sapiens transducin-like enhance... 44 6e-04
BC010100-1|AAH10100.1| 770|Homo sapiens transducin-like enhance... 44 6e-04
AY583460-1|AAS90946.1| 767|Homo sapiens transducin-like enhance... 44 6e-04
AL365190-2|CAI14977.1| 770|Homo sapiens transducin-like enhance... 44 6e-04
AL353682-1|CAI12595.1| 770|Homo sapiens transducin-like enhance... 44 6e-04
AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein. 44 6e-04
AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein. 44 6e-04
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein. 44 8e-04
AY358182-1|AAQ88549.1| 470|Homo sapiens SSGL9393 protein. 44 8e-04
AL157420-1|CAB75650.1| 127|Homo sapiens hypothetical protein pr... 43 0.001
AB209854-1|BAD93091.1| 636|Homo sapiens transducin-like enhance... 43 0.001
BC043247-1|AAH43247.1| 767|Homo sapiens TLE3 protein protein. 43 0.001
BC041831-1|AAH41831.1| 772|Homo sapiens TLE3 protein protein. 43 0.001
BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like ... 43 0.001
BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein. 43 0.001
BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like ... 43 0.001
BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein. 43 0.001
AY583459-1|AAS90945.1| 764|Homo sapiens transducin-like enhance... 43 0.001
AB046767-1|BAB13373.1| 863|Homo sapiens KIAA1547 protein protein. 43 0.001
X87342-1|CAA60780.1| 1015|Homo sapiens Human giant larvae homolo... 42 0.002
EF011612-1|ABK41102.1| 514|Homo sapiens CDW2/WDR26 protein. 42 0.002
BC064994-1|AAH64994.1| 1020|Homo sapiens lethal giant larvae hom... 42 0.002
BC063817-1|AAH63817.1| 404|Homo sapiens WDR26 protein protein. 42 0.002
BC052301-1|AAH52301.2| 514|Homo sapiens WD repeat domain 26 pro... 42 0.002
BC031471-1|AAH31471.2| 373|Homo sapiens WDR26 protein protein. 42 0.002
BC010879-1|AAH10879.1| 356|Homo sapiens lethal giant larvae hom... 42 0.002
BC006503-1|AAH06503.1| 356|Homo sapiens LLGL2 protein protein. 42 0.002
AY304473-1|AAQ74770.1| 514|Homo sapiens WD40 repeat protein 26 ... 42 0.002
AY221751-1|AAO67709.1| 498|Homo sapiens myocardial ischemic pre... 42 0.002
AK024669-1|BAB14955.1| 367|Homo sapiens protein ( Homo sapiens ... 42 0.002
AB209887-1|BAD93124.1| 725|Homo sapiens WD repeat domain 26 var... 42 0.002
U05340-1|AAA19017.1| 499|Homo sapiens p55CDC protein. 42 0.002
L19267-1|AAA35767.1| 553|Homo sapiens protein ( Homo sapiens 59... 42 0.002
DQ473545-1|ABE96834.1| 499|Homo sapiens CDC20 cell division cyc... 42 0.002
BT007388-1|AAP36052.1| 499|Homo sapiens CDC20 cell division cyc... 42 0.002
BC110321-1|AAI10322.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC031294-1|AAH31294.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48 pro... 42 0.002
BC024257-1|AAH24257.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC015998-1|AAH15998.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC013303-1|AAH13303.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC012827-1|AAH12827.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC012803-1|AAH12803.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC010044-1|AAH10044.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC009426-1|AAH09426.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC009425-1|AAH09425.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC006272-1|AAH06272.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC001088-1|AAH01088.1| 499|Homo sapiens cell division cycle 20 ... 42 0.002
BC000624-1|AAH00624.1| 499|Homo sapiens CDC20 protein protein. 42 0.002
AL139289-3|CAB92757.1| 499|Homo sapiens CDC20 cell division cyc... 42 0.002
AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal pro... 42 0.002
AF099644-1|AAD16405.1| 499|Homo sapiens cell cycle protein CDC2... 42 0.002
AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein. 42 0.002
L02547-1|AAA35691.1| 431|Homo sapiens cleavage stimulation fact... 42 0.003
BT007138-1|AAP35802.1| 431|Homo sapiens cleavage stimulation fa... 42 0.003
BC113408-1|AAI13409.1| 1115|Homo sapiens syntaxin binding protei... 42 0.003
BC113382-1|AAI13383.1| 1115|Homo sapiens syntaxin binding protei... 42 0.003
BC107737-1|AAI07738.1| 308|Homo sapiens STXBP5 protein protein. 42 0.003
BC007425-1|AAH07425.1| 431|Homo sapiens cleavage stimulation fa... 42 0.003
BC001011-1|AAH01011.1| 431|Homo sapiens cleavage stimulation fa... 42 0.003
AL590709-5|CAI40741.1| 1115|Homo sapiens syntaxin binding protei... 42 0.003
AL590709-4|CAI40739.1| 1098|Homo sapiens syntaxin binding protei... 42 0.003
AL590709-3|CAI40740.1| 1151|Homo sapiens syntaxin binding protei... 42 0.003
AL356415-3|CAI20241.1| 1151|Homo sapiens syntaxin binding protei... 42 0.003
AL356415-2|CAI20240.1| 1115|Homo sapiens syntaxin binding protei... 42 0.003
AL356415-1|CAI20239.1| 1098|Homo sapiens syntaxin binding protei... 42 0.003
AL355365-6|CAI40424.1| 1151|Homo sapiens syntaxin binding protei... 42 0.003
AL355365-5|CAI40425.1| 1115|Homo sapiens syntaxin binding protei... 42 0.003
AL355365-4|CAI40423.1| 1098|Homo sapiens syntaxin binding protei... 42 0.003
AL121914-12|CAI19328.1| 431|Homo sapiens cleavage stimulation f... 42 0.003
AL121914-11|CAC12718.2| 345|Homo sapiens cleavage stimulation f... 42 0.003
AF103939-1|AAD19904.1| 649|Homo sapiens echinoderm microtubule-... 42 0.003
AB209773-1|BAD93010.1| 574|Homo sapiens echinoderm microtubule ... 42 0.003
U90651-1|AAD08714.1| 441|Homo sapiens embryonic ectoderm develo... 41 0.004
BC068995-1|AAH68995.1| 466|Homo sapiens EED protein protein. 41 0.004
BC047672-1|AAH47672.1| 427|Homo sapiens EED protein protein. 41 0.004
BC036233-1|AAH36233.1| 946|Homo sapiens WDR66 protein protein. 41 0.004
BC012352-1|AAH12352.1| 366|Homo sapiens WDR31 protein protein. 41 0.004
BC002489-1|AAH02489.1| 606|Homo sapiens WD repeat domain 1 prot... 41 0.004
AL607085-2|CAI15166.1| 494|Homo sapiens novel protein protein. 41 0.004
AL449305-1|CAI10961.1| 367|Homo sapiens WD repeat domain 31 pro... 41 0.004
AL137066-1|CAH70096.1| 367|Homo sapiens WD repeat domain 31 pro... 41 0.004
AK093240-1|BAC04106.1| 367|Homo sapiens protein ( Homo sapiens ... 41 0.004
AF177377-1|AAG09279.2| 981|Homo sapiens cytoplasmic protein pro... 41 0.004
AF080227-1|AAC95144.1| 441|Homo sapiens embryonic ectoderm deve... 41 0.004
AF078933-1|AAC68675.1| 427|Homo sapiens WAIT-1 protein. 41 0.004
AF070418-1|AAC23685.1| 517|Homo sapiens embryonic ectoderm deve... 41 0.004
AF020260-1|AAD05045.1| 534|Homo sapiens WDR1 protein protein. 41 0.004
AF020056-1|AAD05044.1| 606|Homo sapiens WDR1 protein protein. 41 0.004
AC006038-1|AAY15086.1| 911|Homo sapiens unknown protein. 41 0.004
AB023199-1|BAA76826.2| 502|Homo sapiens KIAA0982 protein protein. 41 0.004
AB010427-1|BAA31855.2| 606|Homo sapiens NORI-1 protein. 41 0.004
M95627-1|AAA68889.1| 452|Homo sapiens angio-associated migrator... 41 0.005
CR456755-1|CAG33036.1| 452|Homo sapiens AAMP protein. 41 0.005
BC039866-1|AAH39866.2| 434|Homo sapiens angio-associated, migra... 41 0.005
BC028421-1|AAH28421.1| 1154|Homo sapiens WD repeat domain 66 pro... 41 0.005
BC020244-1|AAH20244.1| 429|Homo sapiens Similar to angio-associ... 41 0.005
BC000201-1|AAH00201.1| 606|Homo sapiens WD repeat domain 1 prot... 41 0.005
AY358264-1|AAQ88631.1| 313|Homo sapiens WD40 protein protein. 41 0.005
AK222897-1|BAD96617.1| 606|Homo sapiens WD repeat-containing pr... 41 0.005
AK222764-1|BAD96484.1| 606|Homo sapiens WD repeat-containing pr... 41 0.005
AB209746-1|BAD92983.1| 624|Homo sapiens WD repeat-containing pr... 41 0.005
AK024423-1|BAB15713.1| 182|Homo sapiens FLJ00012 protein protein. 40 0.007
EF011614-1|ABK41104.1| 446|Homo sapiens CDW4/GRWD1 protein. 40 0.010
BX679664-5|CAH71327.1| 919|Homo sapiens WD repeat domain 47 pro... 40 0.010
BX679664-4|CAH71326.1| 920|Homo sapiens WD repeat domain 47 pro... 40 0.010
BX679664-3|CAH71325.1| 891|Homo sapiens WD repeat domain 47 pro... 40 0.010
BC039254-1|AAH39254.1| 893|Homo sapiens WDR47 protein protein. 40 0.010
BC030541-1|AAH30541.1| 466|Homo sapiens WD repeat domain 1 prot... 40 0.010
BC024267-1|AAH24267.1| 594|Homo sapiens TRAF7 protein protein. 40 0.010
BC004519-1|AAH04519.1| 571|Homo sapiens WDR59 protein protein. 40 0.010
BC002440-1|AAH02440.1| 446|Homo sapiens glutamate-rich WD repea... 40 0.010
AY569455-1|AAS68363.1| 670|Homo sapiens TRAF7 protein. 40 0.010
AL449266-4|CAI14352.1| 891|Homo sapiens WD repeat domain 47 pro... 40 0.010
AL449266-3|CAI14353.1| 919|Homo sapiens WD repeat domain 47 pro... 40 0.010
AL449266-2|CAI14351.1| 920|Homo sapiens WD repeat domain 47 pro... 40 0.010
AK074676-1|BAC11130.1| 446|Homo sapiens protein ( Homo sapiens ... 40 0.010
AF337808-1|AAK17998.1| 446|Homo sapiens glutamate rich WD repea... 40 0.010
AB075822-1|BAB85528.1| 445|Homo sapiens KIAA1942 protein protein. 40 0.010
AB020700-1|BAA74916.2| 974|Homo sapiens KIAA0893 protein protein. 40 0.010
BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein... 40 0.013
BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein... 40 0.013
BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase... 40 0.013
BC000162-1|AAH00162.1| 350|Homo sapiens serine/threonine kinase... 40 0.013
AY049776-1|AAL15433.1| 350|Homo sapiens unr-interacting protein... 40 0.013
AJ010025-1|CAB38041.1| 350|Homo sapiens unr-interacting protein... 40 0.013
AB024327-1|BAA75544.1| 350|Homo sapiens WD-40 repeat protein pr... 40 0.013
BC110334-1|AAI10335.1| 454|Homo sapiens F-box and WD repeat dom... 39 0.017
BC018738-1|AAH18738.1| 454|Homo sapiens F-box and WD repeat dom... 39 0.017
AL161911-3|CAI95114.1| 208|Homo sapiens F-box and WD-40 domain ... 39 0.017
AL161911-2|CAI95113.1| 454|Homo sapiens F-box and WD-40 domain ... 39 0.017
AK095246-1|BAC04508.1| 515|Homo sapiens protein ( Homo sapiens ... 39 0.017
AK022484-1|BAB14051.1| 454|Homo sapiens protein ( Homo sapiens ... 39 0.017
AF176698-1|AAF13226.1| 422|Homo sapiens F-box protein FBW2 prot... 39 0.017
AF145024-1|AAP97276.1| 422|Homo sapiens MD6 protein protein. 39 0.017
AF129531-1|AAF04465.1| 422|Homo sapiens F-box protein Fbw2 prot... 39 0.017
AB081750-1|BAC67702.1| 515|Homo sapiens CDC20-like protein form... 39 0.017
AB077043-1|BAC67701.1| 519|Homo sapiens G6VTS76519 protein. 39 0.017
BC106879-1|AAI06880.1| 731|Homo sapiens STRN protein protein. 39 0.022
BC106878-1|AAI06879.1| 755|Homo sapiens STRN protein protein. 39 0.022
BC037168-1|AAH37168.1| 502|Homo sapiens WDR48 protein protein. 39 0.022
AJ223814-1|CAA11560.1| 780|Homo sapiens striatin protein. 39 0.022
AC007382-1|AAF66162.1| 616|Homo sapiens unknown protein. 39 0.022
U17989-1|AAB81551.1| 713|Homo sapiens GS2NA protein. 38 0.029
BC132673-1|AAI32674.1| 713|Homo sapiens striatin, calmodulin bi... 38 0.029
BC126221-1|AAI26222.1| 713|Homo sapiens striatin, calmodulin bi... 38 0.029
AF243424-1|AAF81201.1| 678|Homo sapiens SG2NA beta isoform prot... 38 0.029
AB033065-1|BAA86553.2| 1164|Homo sapiens KIAA1239 protein protein. 38 0.029
U65652-1|AAC52034.1| 252|Homo sapiens HREP protein protein. 38 0.039
U43383-1|AAD10830.1| 196|Homo sapiens protein ( Human unidentif... 38 0.039
U39067-1|AAC97144.1| 325|Homo sapiens translation initiation fa... 38 0.039
U36764-1|AAC50224.1| 325|Homo sapiens TGF-beta receptor interac... 38 0.039
U02609-1|AAA18945.1| 519|Homo sapiens transducin-like protein p... 38 0.039
BT019597-1|AAV38404.1| 325|Homo sapiens eukaryotic translation ... 38 0.039
BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein. 38 0.039
BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein. 38 0.039
BC003140-1|AAH03140.1| 325|Homo sapiens eukaryotic translation ... 38 0.039
BC002485-1|AAH02485.1| 387|Homo sapiens tumor suppressing subtr... 38 0.039
BC001648-1|AAH01648.1| 432|Homo sapiens WD repeat domain 18 pro... 38 0.039
BC000413-1|AAH00413.1| 325|Homo sapiens eukaryotic translation ... 38 0.039
BC000040-1|AAH00040.2| 432|Homo sapiens WD repeat domain 18 pro... 38 0.039
AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase specif... 38 0.039
AL121991-4|CAI22322.1| 325|Homo sapiens eukaryotic translation ... 38 0.039
AL049795-11|CAI22062.1| 125|Homo sapiens eukaryotic translation... 38 0.039
AL049795-10|CAI22061.1| 325|Homo sapiens eukaryotic translation... 38 0.039
AK222652-1|BAD96372.1| 387|Homo sapiens tumor suppressing subtr... 38 0.039
AK126622-1|BAC86616.1| 1060|Homo sapiens protein ( Homo sapiens ... 38 0.039
AK125347-1|BAC86140.1| 277|Homo sapiens protein ( Homo sapiens ... 38 0.039
AK074434-1|BAB85082.1| 293|Homo sapiens protein ( Homo sapiens ... 38 0.039
AK022709-1|BAB14193.1| 800|Homo sapiens protein ( Homo sapiens ... 38 0.039
AF332505-1|AAK97355.1| 756|Homo sapiens apoptosis-inhibitor-lik... 38 0.039
AF045592-1|AAC69998.1| 252|Homo sapiens HREP protein protein. 38 0.039
AF019952-1|AAC51911.1| 387|Homo sapiens tumor suppressing STF c... 38 0.039
>BC052292-1|AAH52292.1| 326|Homo sapiens GBL protein protein.
Length = 326
Score = 343 bits (842), Expect = 6e-94
Identities = 156/280 (55%), Positives = 210/280 (75%), Gaps = 13/280 (4%)
Query: 8 QVNSLEISPT-SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
QVN+LE++P SM+AAAG+QHIR+YDL+S NP+P+ +++ ++KN++ VGF ++G WMYTG
Sbjct: 44 QVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTG 103
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
GEDCTARIWD R+ +CQ+IFQV AP+N V LHP+Q++++VGDQSG IHIWDLKTD N
Sbjct: 104 GEDCTARIWDLRSR-NLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHN 162
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG----QPPHPVPKKHITAHSKY 182
EQLIPE E SI IDP MAAVN+ GNCYVW+L+G + +PK I AH++Y
Sbjct: 163 EQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRY 222
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-------RDTQRWVWDAAFTLDS 235
AL+C+FSPDST+L T S D + KIWRTS+++L+ EL ++ W+W AF+ DS
Sbjct: 223 ALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDS 282
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+++ T SSD+ ARLW +E G ++REY GHQKA+ LAF D
Sbjct: 283 QYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFND 322
>BC017119-1|AAH17119.1| 326|Homo sapiens G protein beta
subunit-like protein.
Length = 326
Score = 343 bits (842), Expect = 6e-94
Identities = 156/280 (55%), Positives = 210/280 (75%), Gaps = 13/280 (4%)
Query: 8 QVNSLEISPT-SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
QVN+LE++P SM+AAAG+QHIR+YDL+S NP+P+ +++ ++KN++ VGF ++G WMYTG
Sbjct: 44 QVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTG 103
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
GEDCTARIWD R+ +CQ+IFQV AP+N V LHP+Q++++VGDQSG IHIWDLKTD N
Sbjct: 104 GEDCTARIWDLRSR-NLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHN 162
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG----QPPHPVPKKHITAHSKY 182
EQLIPE E SI IDP MAAVN+ GNCYVW+L+G + +PK I AH++Y
Sbjct: 163 EQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRY 222
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-------RDTQRWVWDAAFTLDS 235
AL+C+FSPDST+L T S D + KIWRTS+++L+ EL ++ W+W AF+ DS
Sbjct: 223 ALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDS 282
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+++ T SSD+ ARLW +E G ++REY GHQKA+ LAF D
Sbjct: 283 QYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFND 322
>BC001313-1|AAH01313.1| 326|Homo sapiens G protein beta
subunit-like protein.
Length = 326
Score = 343 bits (842), Expect = 6e-94
Identities = 156/280 (55%), Positives = 210/280 (75%), Gaps = 13/280 (4%)
Query: 8 QVNSLEISPT-SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
QVN+LE++P SM+AAAG+QHIR+YDL+S NP+P+ +++ ++KN++ VGF ++G WMYTG
Sbjct: 44 QVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTG 103
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
GEDCTARIWD R+ +CQ+IFQV AP+N V LHP+Q++++VGDQSG IHIWDLKTD N
Sbjct: 104 GEDCTARIWDLRSR-NLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHN 162
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG----QPPHPVPKKHITAHSKY 182
EQLIPE E SI IDP MAAVN+ GNCYVW+L+G + +PK I AH++Y
Sbjct: 163 EQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRY 222
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-------RDTQRWVWDAAFTLDS 235
AL+C+FSPDST+L T S D + KIWRTS+++L+ EL ++ W+W AF+ DS
Sbjct: 223 ALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDS 282
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+++ T SSD+ ARLW +E G ++REY GHQKA+ LAF D
Sbjct: 283 QYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFND 322
>BC088354-1|AAH88354.1| 326|Homo sapiens G protein beta
subunit-like protein.
Length = 326
Score = 340 bits (836), Expect = 3e-93
Identities = 155/280 (55%), Positives = 210/280 (75%), Gaps = 13/280 (4%)
Query: 8 QVNSLEISPT-SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
QVN+LE++P SM+AAAG+QHIR+YDL+S NP+P+ +++ ++KN++ VGF ++G WMYTG
Sbjct: 44 QVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTG 103
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
GEDCTARIWD R+ +CQ+IFQV AP+N V LHP+Q++++VGDQSG I+IWDLKTD N
Sbjct: 104 GEDCTARIWDLRSR-NLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIYIWDLKTDHN 162
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG----QPPHPVPKKHITAHSKY 182
EQLIPE E SI IDP MAAVN+ GNCYVW+L+G + +PK I AH++Y
Sbjct: 163 EQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRY 222
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-------RDTQRWVWDAAFTLDS 235
AL+C+FSPDST+L T S D + KIWRTS+++L+ EL ++ W+W AF+ DS
Sbjct: 223 ALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDS 282
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+++ T SSD+ ARLW +E G ++REY GHQKA+ LAF D
Sbjct: 283 QYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFND 322
>AY223837-1|AAO73410.1| 260|Homo sapiens LST8 protein.
Length = 260
Score = 308 bits (756), Expect = 1e-83
Identities = 139/257 (54%), Positives = 188/257 (73%), Gaps = 12/257 (4%)
Query: 30 LYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIF 89
+YDL+S NP+P+ +++ ++KN++ VGF ++G WMYTGGEDCTARIWD R+ +CQ+IF
Sbjct: 1 MYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSR-NLQCQRIF 59
Query: 90 QVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMM 149
QV AP+N V LHP+Q++++VGDQSG IHIWDLKTD NEQLIPE E SI IDP M
Sbjct: 60 QVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDPDASYM 119
Query: 150 AAVNNKGNCYVWSLSG----QPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAK 205
AAVN+ GNCYVW+L+G + +PK I AH++YAL+C+FSPDST+L T S D + K
Sbjct: 120 AAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCK 179
Query: 206 IWRTSDWALLRELR-------RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLE 258
IW TS+++L+ EL ++ W+W AF+ DS+++ T SSD+ ARLW +E G ++
Sbjct: 180 IWGTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVETGEIK 239
Query: 259 REYCGHQKAITALAFKD 275
REY GHQKA+ LAF D
Sbjct: 240 REYGGHQKAVVCLAFND 256
>BC020499-1|AAH20499.1| 327|Homo sapiens GBL protein protein.
Length = 327
Score = 299 bits (733), Expect = 9e-81
Identities = 136/246 (55%), Positives = 185/246 (75%), Gaps = 13/246 (5%)
Query: 8 QVNSLEISPT-SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
QVN+LE++P SM+AAAG+QHIR+YDL+S NP+P+ +++ ++KN++ VGF ++G WMYTG
Sbjct: 44 QVNALEVTPDRSMIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTG 103
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
GEDCTARIWD R+ +CQ+IFQV AP+N V LHP+Q++++VGDQSG IHIWDLKTD N
Sbjct: 104 GEDCTARIWDLRSR-NLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHN 162
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG----QPPHPVPKKHITAHSKY 182
EQLIPE E SI IDP MAAVN+ GNCYVW+L+G + +PK I AH++Y
Sbjct: 163 EQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRY 222
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-------RDTQRWVWDAAFTLDS 235
AL+C+FSPDST+L T S D + KIWRTS+++L+ EL ++ W+W AF+ DS
Sbjct: 223 ALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDS 282
Query: 236 RFLFTG 241
+++ TG
Sbjct: 283 QYIVTG 288
Score = 37.9 bits (84), Expect = 0.039
Identities = 35/179 (19%), Positives = 71/179 (39%), Gaps = 14/179 (7%)
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE-QLIPEAEASIQDIAIDPAGKMM 149
V + +V H D + G + IWDL++ + Q I + A I + + P +
Sbjct: 84 VNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQCQRIFQVNAPINCVCLHPNQAEL 143
Query: 150 AAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWR 208
+ G ++W L + +P+ ++ S + PD++ + + + +W
Sbjct: 144 IVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAH-----IDPDASYMAAVNSTGNCYVWN 198
Query: 209 TSDWA--LLRELRRDTQ-----RWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
+ + +L T+ R+ F+ DS L T S+D ++W +L E
Sbjct: 199 LTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTE 257
>AF195883-1|AAF04308.1| 230|Homo sapiens G protein beta subunit
protein.
Length = 230
Score = 276 bits (677), Expect = 5e-74
Identities = 128/227 (56%), Positives = 164/227 (72%), Gaps = 12/227 (5%)
Query: 60 GTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIW 119
G WMYTGGEDCTARIWD R+ +CQ+IFQV AP+N V LHP+Q++++VGDQSG IHIW
Sbjct: 1 GRWMYTGGEDCTARIWDLRSR-NLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIW 59
Query: 120 DLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG----QPPHPVPKKH 175
DLKTD NEQLIPE E SI IDP MAAVN+ GNCYVW+L+G + +PK
Sbjct: 60 DLKTDHNEQLIPEPEVSITSAHIDPDASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTK 119
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-------RDTQRWVWD 228
I AH++YAL+C+FSPDST+L T S D + KIWRTS+++L+ EL ++ W+W
Sbjct: 120 IPAHTRYALQCRFSPDSTLLATCSADQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWG 179
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
AF+ DS+++ T SSD+ ARLW +E G ++REY GHQKA+ LAF D
Sbjct: 180 CAFSGDSQYIVTASSDNLARLWCVETGEIKREYGGHQKAVVCLAFND 226
>AK022227-1|BAB13990.1| 217|Homo sapiens protein ( Homo sapiens
cDNA FLJ12165 fis, clone MAMMA1000612, moderately
similar to Homo sapiens G protein beta subunit mRNA. ).
Length = 217
Score = 207 bits (506), Expect = 3e-53
Identities = 91/148 (61%), Positives = 120/148 (81%), Gaps = 2/148 (1%)
Query: 8 QVNSLEISPT-SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
QVN+LE++P S++AAAG+QHIR+YDL+S NP+P+ +++ ++KN++ VGF ++G WMYTG
Sbjct: 63 QVNALEVTPDRSVIAAAGYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTG 122
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
GEDCTARIWD R+ +CQ+IFQV AP+N V LHP+Q++++VGDQSG IHIWDLKTD N
Sbjct: 123 GEDCTARIWDLRSR-NLQCQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHN 181
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNN 154
EQLIPE E SI IDP MAAVN+
Sbjct: 182 EQLIPEPEVSITSAHIDPDASYMAAVNS 209
>AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit
protein.
Length = 655
Score = 78.6 bits (185), Expect = 2e-14
Identities = 57/210 (27%), Positives = 101/210 (48%), Gaps = 12/210 (5%)
Query: 48 SKNVSRVGFQK-NGTWMYTGGEDCTARIWDPRAAPRTRC-QKIFQVQAPVNAVMLHPDQS 105
+ NVS + K +G + TGG+DC +W + + C + +PV +V L+ +
Sbjct: 20 ASNVSSLVLGKASGRLLATGGDDCRVNLW---SINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 106 QIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG 165
I+ G QSG I +WDL+ + + + +A+I + P G+ +A+ + N +W +
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
Query: 166 QPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQR 224
+ HS+ A+RC +FSPD L + + D + K+W + ++ E T
Sbjct: 137 KG----CVFRYRGHSQ-AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 225 WVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V F + L +GSSD R W++E+
Sbjct: 192 -VNVVEFHPNEYLLASGSSDGTIRFWDLEK 220
Score = 54.0 bits (124), Expect = 6e-07
Identities = 36/138 (26%), Positives = 60/138 (43%), Gaps = 6/138 (4%)
Query: 11 SLEISPTSMVAAAGFQ--HIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
SL+ P A+G Q +I+L+D+ V + S+ V + F +G W+ + +
Sbjct: 110 SLDFHPYGEFVASGSQDTNIKLWDIRRKGC--VFRYRGHSQAVRCLRFSPDGKWLASAAD 167
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T ++WD A + PVN V HP++ + G G I WDL+ Q
Sbjct: 168 DHTVKLWDLTAGKMM--SEFPGHTGPVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVS 225
Query: 129 LIPEAEASIQDIAIDPAG 146
I ++ + +P G
Sbjct: 226 RIEGEPGPVRSVLFNPDG 243
Score = 41.9 bits (94), Expect = 0.002
Identities = 34/153 (22%), Positives = 66/153 (43%), Gaps = 6/153 (3%)
Query: 122 KTDQNEQLIPEAEASIQDIAIDPA-GKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHS 180
KT Q I +++ + + A G+++A + +WS++ P+ + +T H+
Sbjct: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSIN--KPNCIMS--LTGHT 63
Query: 181 KYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFT 240
+ + ++V S S ++W +LR L + + F F+ +
Sbjct: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLM-GLKANICSLDFHPYGEFVAS 122
Query: 241 GSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
GS D+ +LW+I R Y GH +A+ L F
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
Score = 39.5 bits (88), Expect = 0.013
Identities = 31/191 (16%), Positives = 77/191 (40%), Gaps = 6/191 (3%)
Query: 84 RCQKIFQVQAPVNAVMLHPDQSQIMV-GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAI 142
+ Q+I + V++++L +++ G +++W + + + ++ + +
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL 71
Query: 143 DPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDC 202
+ +++ A + G+ VW L + + F P + + S D
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKI----LRTLMGLKANICSLDFHPYGEFVASGSQDT 127
Query: 203 SAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYC 262
+ K+W + R +Q V F+ D ++L + + D +LW++ G + E+
Sbjct: 128 NIKLWDIRRKGCVFRYRGHSQA-VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186
Query: 263 GHQKAITALAF 273
GH + + F
Sbjct: 187 GHTGPVNVVEF 197
>CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein.
Length = 655
Score = 77.8 bits (183), Expect = 4e-14
Identities = 57/210 (27%), Positives = 101/210 (48%), Gaps = 12/210 (5%)
Query: 48 SKNVSRVGFQK-NGTWMYTGGEDCTARIWDPRAAPRTRC-QKIFQVQAPVNAVMLHPDQS 105
+ NVS + K +G + TGG+DC +W + + C + +PV +V L+ +
Sbjct: 20 ASNVSSLVLGKASGRLLATGGDDCRVNLW---SINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 106 QIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG 165
I+ G QSG I +WDL+ + + + +A+I + P G+ +A+ + N +W +
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
Query: 166 QPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQR 224
+ HS+ A+RC +FSPD L + + D + K+W + ++ E T
Sbjct: 137 KG----CVFRYRGHSQ-AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 225 WVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V F + L +GSSD R W++E+
Sbjct: 192 -VNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 11 SLEISPTSMVAAAGFQ--HIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
SL+ P A+G Q +I+L+D+ V + S+ V + F +G W+ + +
Sbjct: 110 SLDFHPYGEFVASGSQDTNIKLWDIRRKGC--VFRYRGHSQAVRCLRFSPDGKWLASAAD 167
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T ++WD A + PVN V HP++ + G I WDL+ Q
Sbjct: 168 DHTVKLWDLTAGKMM--SEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVS 225
Query: 129 LIPEAEASIQDIAIDPAG 146
I ++ + +P G
Sbjct: 226 CIEGEPGPVRSVLFNPDG 243
Score = 44.0 bits (99), Expect = 6e-04
Identities = 32/191 (16%), Positives = 78/191 (40%), Gaps = 6/191 (3%)
Query: 84 RCQKIFQVQAPVNAVMLHPDQSQIMV-GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAI 142
+ Q+I + V++++L +++ G +++W + + + ++ + +
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL 71
Query: 143 DPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDC 202
+ +++ A + G+ VW L + + H F P + + S D
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKI----LRTLMGHKANICSLDFHPYGEFVASGSQDT 127
Query: 203 SAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYC 262
+ K+W + R +Q V F+ D ++L + + D +LW++ G + E+
Sbjct: 128 NIKLWDIRRKGCVFRYRGHSQA-VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186
Query: 263 GHQKAITALAF 273
GH + + F
Sbjct: 187 GHTGPVNVVEF 197
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 122 KTDQNEQLIPEAEASIQDIAIDPA-GKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHS 180
KT Q I +++ + + A G+++A + +WS++ P+ + +T H+
Sbjct: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSIN--KPNCIMS--LTGHT 63
Query: 181 KYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFT 240
+ + ++V S S ++W +LR L + F F+ +
Sbjct: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKAN-ICSLDFHPYGEFVAS 122
Query: 241 GSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
GS D+ +LW+I R Y GH +A+ L F
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
>BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80
(WD40-containing) subunit B 1 protein.
Length = 655
Score = 77.8 bits (183), Expect = 4e-14
Identities = 57/210 (27%), Positives = 101/210 (48%), Gaps = 12/210 (5%)
Query: 48 SKNVSRVGFQK-NGTWMYTGGEDCTARIWDPRAAPRTRC-QKIFQVQAPVNAVMLHPDQS 105
+ NVS + K +G + TGG+DC +W + + C + +PV +V L+ +
Sbjct: 20 ASNVSSLVLGKASGRLLATGGDDCRVNLW---SINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 106 QIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG 165
I+ G QSG I +WDL+ + + + +A+I + P G+ +A+ + N +W +
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
Query: 166 QPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQR 224
+ HS+ A+RC +FSPD L + + D + K+W + ++ E T
Sbjct: 137 KG----CVFRYRGHSQ-AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 225 WVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V F + L +GSSD R W++E+
Sbjct: 192 -VNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 11 SLEISPTSMVAAAGFQ--HIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
SL+ P A+G Q +I+L+D+ V + S+ V + F +G W+ + +
Sbjct: 110 SLDFHPYGEFVASGSQDTNIKLWDIRRKGC--VFRYRGHSQAVRCLRFSPDGKWLASAAD 167
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T ++WD A + PVN V HP++ + G I WDL+ Q
Sbjct: 168 DHTVKLWDLTAGKMM--SEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVS 225
Query: 129 LIPEAEASIQDIAIDPAG 146
I ++ + +P G
Sbjct: 226 CIEGEPGPVRSVLFNPDG 243
Score = 44.0 bits (99), Expect = 6e-04
Identities = 32/191 (16%), Positives = 78/191 (40%), Gaps = 6/191 (3%)
Query: 84 RCQKIFQVQAPVNAVMLHPDQSQIMV-GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAI 142
+ Q+I + V++++L +++ G +++W + + + ++ + +
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL 71
Query: 143 DPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDC 202
+ +++ A + G+ VW L + + H F P + + S D
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKI----LRTLMGHKANICSLDFHPYGEFVASGSQDT 127
Query: 203 SAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYC 262
+ K+W + R +Q V F+ D ++L + + D +LW++ G + E+
Sbjct: 128 NIKLWDIRRKGCVFRYRGHSQA-VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186
Query: 263 GHQKAITALAF 273
GH + + F
Sbjct: 187 GHTGPVNVVEF 197
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 122 KTDQNEQLIPEAEASIQDIAIDPA-GKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHS 180
KT Q I +++ + + A G+++A + +WS++ P+ + +T H+
Sbjct: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSIN--KPNCIMS--LTGHT 63
Query: 181 KYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFT 240
+ + ++V S S ++W +LR L + F F+ +
Sbjct: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKAN-ICSLDFHPYGEFVAS 122
Query: 241 GSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
GS D+ +LW+I R Y GH +A+ L F
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
>BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat
containing) subunit B 1 protein.
Length = 655
Score = 77.8 bits (183), Expect = 4e-14
Identities = 57/210 (27%), Positives = 101/210 (48%), Gaps = 12/210 (5%)
Query: 48 SKNVSRVGFQK-NGTWMYTGGEDCTARIWDPRAAPRTRC-QKIFQVQAPVNAVMLHPDQS 105
+ NVS + K +G + TGG+DC +W + + C + +PV +V L+ +
Sbjct: 20 ASNVSSLVLGKASGRLLATGGDDCRVNLW---SINKPNCIMSLTGHTSPVESVRLNTPEE 76
Query: 106 QIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSG 165
I+ G QSG I +WDL+ + + + +A+I + P G+ +A+ + N +W +
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
Query: 166 QPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQR 224
+ HS+ A+RC +FSPD L + + D + K+W + ++ E T
Sbjct: 137 KG----CVFRYRGHSQ-AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 225 WVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V F + L +GSSD R W++E+
Sbjct: 192 -VNVVEFHPNEYLLASGSSDRTIRFWDLEK 220
Score = 51.2 bits (117), Expect = 4e-06
Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 6/138 (4%)
Query: 11 SLEISPTSMVAAAGFQ--HIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
SL+ P A+G Q +I+L+D+ V + S+ V + F +G W+ + +
Sbjct: 110 SLDFHPYGEFVASGSQDTNIKLWDIRRKGC--VFRYRGHSQAVRCLRFSPDGKWLASAAD 167
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T ++WD A + PVN V HP++ + G I WDL+ Q
Sbjct: 168 DHTVKLWDLTAGKMM--SEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVS 225
Query: 129 LIPEAEASIQDIAIDPAG 146
I ++ + +P G
Sbjct: 226 CIEGEPGPVRSVLFNPDG 243
Score = 44.0 bits (99), Expect = 6e-04
Identities = 32/191 (16%), Positives = 78/191 (40%), Gaps = 6/191 (3%)
Query: 84 RCQKIFQVQAPVNAVMLHPDQSQIMV-GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAI 142
+ Q+I + V++++L +++ G +++W + + + ++ + +
Sbjct: 12 KLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRL 71
Query: 143 DPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDC 202
+ +++ A + G+ VW L + + H F P + + S D
Sbjct: 72 NTPEELIVAGSQSGSIRVWDLEAAKI----LRTLMGHKANICSLDFHPYGEFVASGSQDT 127
Query: 203 SAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYC 262
+ K+W + R +Q V F+ D ++L + + D +LW++ G + E+
Sbjct: 128 NIKLWDIRRKGCVFRYRGHSQA-VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186
Query: 263 GHQKAITALAF 273
GH + + F
Sbjct: 187 GHTGPVNVVEF 197
Score = 42.3 bits (95), Expect = 0.002
Identities = 34/153 (22%), Positives = 65/153 (42%), Gaps = 6/153 (3%)
Query: 122 KTDQNEQLIPEAEASIQDIAIDPA-GKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHS 180
KT Q I +++ + + A G+++A + +WS++ P+ + +T H+
Sbjct: 8 KTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSIN--KPNCIMS--LTGHT 63
Query: 181 KYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFT 240
+ + ++V S S ++W +LR L + F F+ +
Sbjct: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKAN-ICSLDFHPYGEFVAS 122
Query: 241 GSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
GS D+ +LW+I R Y GH +A+ L F
Sbjct: 123 GSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRF 155
>Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-binding
protein beta3 subunit protein.
Length = 340
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318
Score = 34.3 bits (75), Expect = 0.48
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 268
Query: 184 LRC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 327
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 32.7 bits (71), Expect = 1.5
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSL 280
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 281 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain
protein.
Length = 340
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318
Score = 34.3 bits (75), Expect = 0.48
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 268
Query: 184 LRC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 327
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 32.7 bits (71), Expect = 1.5
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSL 280
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 281 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein.
Length = 340
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318
Score = 34.3 bits (75), Expect = 0.48
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 268
Query: 184 LRC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 327
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 32.7 bits (71), Expect = 1.5
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSL 280
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 281 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 40.3 bits (90), Expect = 0.007
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318
Score = 34.7 bits (76), Expect = 0.36
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 268
Query: 184 LRCK-----FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 327
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSL 280
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 281 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein.
Length = 297
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 35.9 bits (79), Expect = 0.16
Identities = 25/115 (21%), Positives = 43/115 (37%), Gaps = 6/115 (5%)
Query: 158 CYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLR 216
C +W + +GQ K H+ + SPD + ++ + D SAK+W + +
Sbjct: 166 CALWDIETGQQ-----KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQ 220
Query: 217 ELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
F+L R LF G D +W+ + GH ++ L
Sbjct: 221 TFTGHESDINAICFFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 275
Score = 35.5 bits (78), Expect = 0.21
Identities = 30/150 (20%), Positives = 55/150 (36%), Gaps = 6/150 (4%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAH-SKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
+ ++ T H S C FS +L D + +W + + L
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGH 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
R V T D + TGS DS+ ++WN
Sbjct: 269 DNR-VSCLGVTADGMAVATGSWDSFLKIWN 297
>BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 40.3 bits (90), Expect = 0.007
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318
Score = 34.7 bits (76), Expect = 0.36
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 268
Query: 184 LRCK-----FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 327
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSL 280
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 281 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 40.3 bits (90), Expect = 0.007
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318
Score = 34.7 bits (76), Expect = 0.36
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 268
Query: 184 LRCK-----FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 269 IICSITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 327
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSL 280
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 281 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318
Score = 34.3 bits (75), Expect = 0.48
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 268
Query: 184 LRC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 327
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 32.7 bits (71), Expect = 1.5
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSL 280
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 281 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide binding
protein beta 3 protein.
Length = 340
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 116 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 175 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 213 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 318
Score = 34.3 bits (75), Expect = 0.48
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 215
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 216 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 268
Query: 184 LRC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 269 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 327
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 328 ATGSWDSFLKIWN 340
Score = 32.7 bits (71), Expect = 1.5
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 221 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSL 280
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 281 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 340
>AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-binding
protein, beta-3 subunit variant protein.
Length = 327
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/181 (23%), Positives = 80/181 (44%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + +WD T IP + + A P+G +A
Sbjct: 43 AKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 102
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + ++AH+ Y C+F D+ +VT+SGD + +W
Sbjct: 103 GLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNN-IVTSSGDTTCALWDIETG 161
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T + A + D +G+ D+ A+LW++ GT + + GH+ I A+
Sbjct: 162 QQKTVFVGHTGDCM-SLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 220
Query: 273 F 273
F
Sbjct: 221 F 221
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 5/170 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D + I+ +WD++T Q + + +A+ P + + + +W
Sbjct: 140 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 199
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ ++ T H F P+ + T S D S +++ +D L+
Sbjct: 200 VR----EGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHES 255
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ AF+L R LF G D +W+ + GH ++ L
Sbjct: 256 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCL 305
Score = 34.3 bits (75), Expect = 0.48
Identities = 38/193 (19%), Positives = 71/193 (36%), Gaps = 17/193 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQA-PVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
T D T +WD + + +F ++ + PD + + G +WD++
Sbjct: 146 TSSGDTTCALWDIETGQQ---KTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVRE 202
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q E+ I I P G+ + ++ +C ++ L + + S +
Sbjct: 203 GTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRAD-------QELICFSHES 255
Query: 184 LRC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
+ C FS +L D + +W + + L R V T D +
Sbjct: 256 IICGITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNR-VSCLGVTADGMAV 314
Query: 239 FTGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 315 ATGSWDSFLKIWN 327
Score = 32.7 bits (71), Expect = 1.5
Identities = 20/120 (16%), Positives = 46/120 (38%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG + TG +D + R++D RA C + + +V
Sbjct: 208 TFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSL 267
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ G ++WD + ++ + + + + G +A + +W+
Sbjct: 268 SGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN 327
>X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRNA
for beta-subunit signal transducing proteins Gs/Gi
(beta-G). ).
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein.
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein.
Length = 332
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 47.6 bits (108), Expect = 5e-05
Identities = 31/151 (20%), Positives = 64/151 (42%), Gaps = 8/151 (5%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVW 161
I ++ +G+++ A + NC VW
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVW 297
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 33.9 bits (74), Expect = 0.63
Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF +++ + F NG TG +D T R++D RA + + +V
Sbjct: 221 TFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSK 280
Query: 103 DQSQIMVGDQSGIIHIWD-LKTDQ 125
++ G ++WD LK D+
Sbjct: 281 SGRLLLAGYDDFNCNVWDALKADR 304
Score = 32.7 bits (71), Expect = 1.5
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPR 82
+D +WD A R
Sbjct: 289 YDDFNCNVWDALKADR 304
Score = 31.9 bits (69), Expect = 2.5
Identities = 22/99 (22%), Positives = 35/99 (35%), Gaps = 2/99 (2%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL 163
Q E+ I I P G A ++ C ++ L
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDL 255
>BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38
protein.
Length = 314
Score = 73.7 bits (173), Expect = 6e-13
Identities = 58/249 (23%), Positives = 102/249 (40%), Gaps = 7/249 (2%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+VNS SP + G + +Y + + + + V F +G +
Sbjct: 23 EVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASAS 82
Query: 68 EDCTARIWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
DCT R+WD R +C ++ + Q V V PD Q+ G + +WD+++ Q
Sbjct: 83 CDCTVRLWD---VARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
+L+ SIQ P +A + ++W L P V + + HS + C
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTP-AVSHQALEGHSA-NISC 197
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
S +L + S D + IW+ + +LL +L+ WV AF+ D +L +
Sbjct: 198 LCYSASGLLASGSWDKTIHIWKPTTSSLLIQLKGHV-TWVKSIAFSPDELWLASAGYSRM 256
Query: 247 ARLWNIERG 255
++W+ G
Sbjct: 257 VKVWDCNTG 265
Score = 63.7 bits (148), Expect = 7e-10
Identities = 41/138 (29%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Query: 137 IQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
+ A P G+M+ + G Y W SGQ + H+ C+FSPD +
Sbjct: 24 VNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLW-----RLGGHTGPVKFCRFSPDGHLF 78
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERG 255
+ S DC+ ++W + LR L+ QR V +F+ DSR L +G D LW+++ G
Sbjct: 79 ASASCDCTVRLWDVARAKCLRVLKGH-QRSVETVSFSPDSRQLASGGWDKRVMLWDVQSG 137
Query: 256 TLEREYCGHQKAITALAF 273
+ R GH+ +I + F
Sbjct: 138 QMLRLLVGHRDSIQSSDF 155
Score = 48.4 bits (110), Expect = 3e-05
Identities = 47/224 (20%), Positives = 89/224 (39%), Gaps = 13/224 (5%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+RL+D++ A + + ++V V F + + +GG D +WD ++ R
Sbjct: 87 VRLWDVARAKC--LRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRL-- 142
Query: 88 IFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ---NEQLIPEAEASIQDIAIDP 144
+ + + + P + + G +HIWDL+ + Q + A+I +
Sbjct: 143 LVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSA 202
Query: 145 AGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
+G + + +K ++W + K H+T A FSPD L +
Sbjct: 203 SGLLASGSWDK-TIHIWKPTTSSLLIQLKGHVTWVKSIA----FSPDELWLASAGYSRMV 257
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
K+W + L L + AFT D + L +G++D R
Sbjct: 258 KVWDCNTGKCLETL-KGVLDVAHTCAFTPDGKILVSGAADQTRR 300
Score = 42.3 bits (95), Expect = 0.002
Identities = 45/226 (19%), Positives = 84/226 (37%), Gaps = 11/226 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+ F +G + TG ED W+ R+ ++ PV PD
Sbjct: 24 VNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLL--WRLGGHTGPVKFCRFSPDGHLFASA 81
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPH 169
+ +WD+ + +++ + S++ ++ P + +A+ +W + SGQ
Sbjct: 82 SCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM-- 139
Query: 170 PVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW--RTSDWALLRELRRDTQRWVW 227
+ + H FSP L T S D + IW R A+ + +
Sbjct: 140 ---LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANIS 196
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
++ S L +GS D +W +L + GH + ++AF
Sbjct: 197 CLCYSA-SGLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAF 241
>AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide binding
protein beta 1 protein.
Length = 340
Score = 73.7 bits (173), Expect = 6e-13
Identities = 43/181 (23%), Positives = 77/181 (42%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C +++L + + + + H+ Y C+F D +VT+SGD + +W
Sbjct: 116 GLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFL-DDNQIVTSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
T V + D+R +G+ D+ A+LW++ G + + GH+ I A+
Sbjct: 175 QQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 152 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 209
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 210 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 267 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 322
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 323 DGMAVATGSWDSFLKIW 339
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 213 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 269 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 270 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69
protein.
Length = 415
Score = 73.3 bits (172), Expect = 8e-13
Identities = 56/245 (22%), Positives = 100/245 (40%), Gaps = 11/245 (4%)
Query: 8 QVNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
++ L +P S + A G +L+D+ N + V T S + + F +G + T
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQ--NGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 66 GGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
G D T +WD + + A +++ + D S I+ G +WD +
Sbjct: 237 GSFDHTVVVWDADTGRKVNI--LIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALR 185
+ + I D D GK++A + G ++S + + + K + H +
Sbjct: 295 CVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKC--IAK--LEGHEGEISK 350
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
F+P L+T S D +A+IW L+ L T ++ AF + TGS D+
Sbjct: 351 ISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDE-IFSCAFNYKGNIVITGSKDN 409
Query: 246 YARLW 250
R+W
Sbjct: 410 TCRIW 414
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/231 (20%), Positives = 89/231 (38%), Gaps = 7/231 (3%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + + F T + TG D TA++WD + + A + ++ +
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS--AEIISLSFNT 229
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+I+ G + +WD T + ++ A I + + ++ + C +W
Sbjct: 230 SGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD 289
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
+ +T H L F ++ T S D +A+I+ + + +L
Sbjct: 290 ATNGKCVAT----LTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ +F L TGSSD AR+W+ + G + GH I + AF
Sbjct: 346 GE-ISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/250 (18%), Positives = 98/250 (39%), Gaps = 12/250 (4%)
Query: 29 RLYDLSSANPDPVTTFEDISKNVSRVGFQKN-GTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+L+D +S + + T E V + F G + TG D T ++W +C
Sbjct: 117 KLWDTASG--EELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETG---KCYH 171
Query: 88 IFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAG 146
F+ A + + +P + + G +WD++ + + A I ++ + +G
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSG 231
Query: 147 KMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKI 206
+ + VW + + H F+ D ++++T S D + K+
Sbjct: 232 DRIITGSFDHTVVVWDADTGRKVNI----LIGHCAEISSASFNWDCSLILTGSMDKTCKL 287
Query: 207 WRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQK 266
W ++ + L + D+ F + + T S+D AR+++ + GH+
Sbjct: 288 WDATNGKCVATLTGHDDE-ILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEG 346
Query: 267 AITALAFKDQ 276
I+ ++F Q
Sbjct: 347 EISKISFNPQ 356
Score = 51.2 bits (117), Expect = 4e-06
Identities = 45/225 (20%), Positives = 84/225 (37%), Gaps = 10/225 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVML-HPDQSQIMV 109
++ V K+G+ TG D T ++WD A + + V A+ +P +I
Sbjct: 95 LTNVALNKSGSCFITGSYDRTCKLWD--TASGEELNTLEGHRNVVYAIAFNNPYGDKIAT 152
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPP 168
G +W ++T + A I ++ +P ++A + +W + +G+
Sbjct: 153 GSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV 212
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
+ + HS + F+ ++T S D + +W + L +
Sbjct: 213 YT-----LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAE-ISS 266
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
A+F D + TGS D +LW+ G GH I F
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCF 311
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 2/104 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K + AH + + +T S D + K+W T+ L L + V+ AF
Sbjct: 86 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGH-RNVVYAIAFNN 144
Query: 234 D-SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
+ TGS D +LW++E G + GH I L+F Q
Sbjct: 145 PYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 188
>AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ40090 fis, clone TESTI2003596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 415
Score = 73.3 bits (172), Expect = 8e-13
Identities = 56/245 (22%), Positives = 100/245 (40%), Gaps = 11/245 (4%)
Query: 8 QVNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
++ L +P S + A G +L+D+ N + V T S + + F +G + T
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQ--NGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 66 GGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
G D T +WD + + A +++ + D S I+ G +WD +
Sbjct: 237 GSFDHTVVVWDADTGRKVNI--LIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALR 185
+ + I D D GK++A + G ++S + + + K + H +
Sbjct: 295 CVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKC--IAK--LEGHEGEISK 350
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
F+P L+T S D +A+IW L+ L T ++ AF + TGS D+
Sbjct: 351 ISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDE-IFSCAFNYKGNIVITGSKDN 409
Query: 246 YARLW 250
R+W
Sbjct: 410 TCRIW 414
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/231 (20%), Positives = 89/231 (38%), Gaps = 7/231 (3%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + + F T + TG D TA++WD + + A + ++ +
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS--AEIISLSFNT 229
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+I+ G + +WD T + ++ A I + + ++ + C +W
Sbjct: 230 SGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD 289
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
+ +T H L F ++ T S D +A+I+ + + +L
Sbjct: 290 ATNGKCVAT----LTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ +F L TGSSD AR+W+ + G + GH I + AF
Sbjct: 346 GE-ISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/250 (18%), Positives = 98/250 (39%), Gaps = 12/250 (4%)
Query: 29 RLYDLSSANPDPVTTFEDISKNVSRVGFQKN-GTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+L+D +S + + T E V + F G + TG D T ++W +C
Sbjct: 117 KLWDTASG--EELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETG---KCYH 171
Query: 88 IFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAG 146
F+ A + + +P + + G +WD++ + + A I ++ + +G
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSG 231
Query: 147 KMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKI 206
+ + VW + + H F+ D ++++T S D + K+
Sbjct: 232 DRIITGSFDHTVVVWDADTGRKVNI----LIGHCAEISSASFNWDCSLILTGSMDKTCKL 287
Query: 207 WRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQK 266
W ++ + L + D+ F + + T S+D AR+++ + GH+
Sbjct: 288 WDATNGKCVATLTGHDDE-ILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEG 346
Query: 267 AITALAFKDQ 276
I+ ++F Q
Sbjct: 347 EISKISFNPQ 356
Score = 51.2 bits (117), Expect = 4e-06
Identities = 45/225 (20%), Positives = 84/225 (37%), Gaps = 10/225 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVML-HPDQSQIMV 109
++ V K+G+ TG D T ++WD A + + V A+ +P +I
Sbjct: 95 LTNVALNKSGSCFITGSYDRTCKLWD--TASGEELNTLEGHRNVVYAIAFNNPYGDKIAT 152
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPP 168
G +W ++T + A I ++ +P ++A + +W + +G+
Sbjct: 153 GSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV 212
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
+ + HS + F+ ++T S D + +W + L +
Sbjct: 213 YT-----LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAE-ISS 266
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
A+F D + TGS D +LW+ G GH I F
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCF 311
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 2/104 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K + AH + + +T S D + K+W T+ L L + V+ AF
Sbjct: 86 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGH-RNVVYAIAFNN 144
Query: 234 D-SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
+ TGS D +LW++E G + GH I L+F Q
Sbjct: 145 PYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 188
>AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 73.3 bits (172), Expect = 8e-13
Identities = 56/245 (22%), Positives = 100/245 (40%), Gaps = 11/245 (4%)
Query: 8 QVNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
++ L +P S + A G +L+D+ N + V T S + + F +G + T
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQ--NGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 66 GGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
G D T +WD + + A +++ + D S I+ G +WD +
Sbjct: 237 GSFDHTVVVWDADTGRKVNI--LIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALR 185
+ + I D D GK++A + G ++S + + + K + H +
Sbjct: 295 CVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKC--IAK--LEGHEGEISK 350
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
F+P L+T S D +A+IW L+ L T ++ AF + TGS D+
Sbjct: 351 ISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDE-IFSCAFNYKGNIVITGSKDN 409
Query: 246 YARLW 250
R+W
Sbjct: 410 TCRIW 414
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/231 (20%), Positives = 89/231 (38%), Gaps = 7/231 (3%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + + F T + TG D TA++WD + + A + ++ +
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS--AEIISLSFNT 229
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+I+ G + +WD T + ++ A I + + ++ + C +W
Sbjct: 230 SGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD 289
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
+ +T H L F ++ T S D +A+I+ + + +L
Sbjct: 290 ATNGKCVAT----LTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ +F L TGSSD AR+W+ + G + GH I + AF
Sbjct: 346 GE-ISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/250 (18%), Positives = 98/250 (39%), Gaps = 12/250 (4%)
Query: 29 RLYDLSSANPDPVTTFEDISKNVSRVGFQKN-GTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+L+D +S + + T E V + F G + TG D T ++W +C
Sbjct: 117 KLWDTASG--EELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETG---KCYH 171
Query: 88 IFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAG 146
F+ A + + +P + + G +WD++ + + A I ++ + +G
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSG 231
Query: 147 KMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKI 206
+ + VW + + H F+ D ++++T S D + K+
Sbjct: 232 DRIITGSFDHTVVVWDADTGRKVNI----LIGHCAEISSASFNWDCSLILTGSMDKTCKL 287
Query: 207 WRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQK 266
W ++ + L + D+ F + + T S+D AR+++ + GH+
Sbjct: 288 WDATNGKCVATLTGHDDE-ILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEG 346
Query: 267 AITALAFKDQ 276
I+ ++F Q
Sbjct: 347 EISKISFNPQ 356
Score = 51.2 bits (117), Expect = 4e-06
Identities = 45/225 (20%), Positives = 84/225 (37%), Gaps = 10/225 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVML-HPDQSQIMV 109
++ V K+G+ TG D T ++WD A + + V A+ +P +I
Sbjct: 95 LTNVALNKSGSCFITGSYDRTCKLWD--TASGEELNTLEGHRNVVYAIAFNNPYGDKIAT 152
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPP 168
G +W ++T + A I ++ +P ++A + +W + +G+
Sbjct: 153 GSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV 212
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
+ + HS + F+ ++T S D + +W + L +
Sbjct: 213 YT-----LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAE-ISS 266
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
A+F D + TGS D +LW+ G GH I F
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCF 311
Score = 39.5 bits (88), Expect = 0.013
Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 2/104 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K + AH + + +T S D + K+W T+ L L + V+ AF
Sbjct: 86 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGH-RNVVYAIAFNN 144
Query: 234 D-SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
+ TGS D +LW++E G + GH I L+F Q
Sbjct: 145 PYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 188
>BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein.
Length = 452
Score = 72.1 bits (169), Expect = 2e-12
Identities = 56/215 (26%), Positives = 89/215 (41%), Gaps = 10/215 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
VS F + T + +G DCT ++WDP R + + +APV + D S+++
Sbjct: 131 VSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFE-HRPKAPVVECSITGDSSRVIAA 189
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN--KGNCYVWSLSGQPP 168
+ WDL+T + + + I P GK + + + G C +
Sbjct: 190 SYDKTVRAWDLETGKLLWKV-RYDTFIVSCKFSPDGKYVVSGFDVDHGIC-IMDAENITT 247
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
V K H H++ C F PDS + + S D KIW + A L + + + +
Sbjct: 248 VSVIKDH---HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISN 304
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
FT FL T S D ++WN+ G E CG
Sbjct: 305 CCFTFSGHFLCTSSWDKNLKIWNVHTG--EFRNCG 337
Score = 56.8 bits (131), Expect = 8e-08
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 135 ASIQDIAID--PAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDS 192
A++ +A+D P ++ + +W P +P K ++ H C F D
Sbjct: 82 ATLDPLALDREPPPHLLPEKHQVPEKLIWG-DQDPLSKIPFKILSGHEHAVSTCHFCVDD 140
Query: 193 TMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNI 252
T L++ S DC+ K+W D +++R+ + V + + T DS + S D R W++
Sbjct: 141 TKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRAWDL 200
Query: 253 ERGTL 257
E G L
Sbjct: 201 ETGKL 205
Score = 49.2 bits (112), Expect = 2e-05
Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 4/162 (2%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVN 153
+ + PD ++ I IWD+ + I +A ++ I + +G + +
Sbjct: 259 ITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSS 318
Query: 154 NKGNCYVWSL-SGQPPH-PVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
N +W++ +G+ + + H C F+ DS+ L++ D + IW ++
Sbjct: 319 WDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAE 378
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
L+ WV D A + + +++ + S D RLWNIE
Sbjct: 379 GYRKLSLKGHND-WVMDVAISNNKKWILSASKDRTMRLWNIE 419
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/181 (24%), Positives = 71/181 (39%), Gaps = 10/181 (5%)
Query: 102 PDQSQIMVG-DQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVNNKGNCY 159
PD ++ G D I I D + +I + SI DP + +A+V+
Sbjct: 222 PDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIK 281
Query: 160 VWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWR--TSDW---AL 214
+W ++ Q K AHS C F+ L T+S D + KIW T ++
Sbjct: 282 IWDVTSQATLLTITK---AHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGA 338
Query: 215 LRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFK 274
L + + V F DS FL +G D +W++ G + GH + +A
Sbjct: 339 CVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAIS 398
Query: 275 D 275
+
Sbjct: 399 N 399
>AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ16579 fis, clone TESTI2049956, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 472
Score = 72.1 bits (169), Expect = 2e-12
Identities = 58/231 (25%), Positives = 96/231 (41%), Gaps = 14/231 (6%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
VS F + T + +G DCT ++WDP R + + +APV + D S+++
Sbjct: 105 VSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFE-HRPKAPVVECSITGDSSRVIAA 163
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN--KGNCYVWSLSGQPP 168
+ WDL+T + + + I P GK + + + G C +
Sbjct: 164 SYDKTVRAWDLETGKLLWKV-RYDTFIVSCKFSPDGKYVVSGFDVDHGIC-IMDAENITT 221
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
V K H H++ C F PDS + + S D KIW + A L + + + +
Sbjct: 222 VSVIKDH---HTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISN 278
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTL-EREYC-----GHQKAITALAF 273
FT FL T S D ++WN+ G R C GH+ ++++ F
Sbjct: 279 CCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHF 329
Score = 56.8 bits (131), Expect = 8e-08
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 3/125 (2%)
Query: 135 ASIQDIAID--PAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDS 192
A++ +A+D P ++ + +W P +P K ++ H C F D
Sbjct: 56 ATLDPLALDREPPPHLLPEKHQVPEKLIWG-DQDPLSKIPFKILSGHEHAVSTCHFCVDD 114
Query: 193 TMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNI 252
T L++ S DC+ K+W D +++R+ + V + + T DS + S D R W++
Sbjct: 115 TKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGDSSRVIAASYDKTVRAWDL 174
Query: 253 ERGTL 257
E G L
Sbjct: 175 ETGKL 179
Score = 49.6 bits (113), Expect = 1e-05
Identities = 35/162 (21%), Positives = 68/162 (41%), Gaps = 4/162 (2%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVN 153
+ + PD ++ I IWD+ + I +A ++ I + +G + +
Sbjct: 233 ITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSNAISNCCFTFSGHFLCTSS 292
Query: 154 NKGNCYVWSL-SGQ-PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
N +W++ +G+ + H C F+ DS+ L++ D + IW ++
Sbjct: 293 WDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAE 352
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
L+ WV D A + + +++ + S D RLWNIE
Sbjct: 353 GYRKLSLKGHND-WVMDVAISNNKKWILSASKDRTMRLWNIE 393
Score = 44.0 bits (99), Expect = 6e-04
Identities = 43/181 (23%), Positives = 68/181 (37%), Gaps = 10/181 (5%)
Query: 102 PDQSQIMVG-DQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVNNKGNCY 159
PD ++ G D I I D + +I + SI DP + +A+V+
Sbjct: 196 PDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIK 255
Query: 160 VWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRE-- 217
+W ++ Q K AHS C F+ L T+S D + KIW
Sbjct: 256 IWDVTSQATLLTITK---AHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGA 312
Query: 218 ---LRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFK 274
L + + V F DS FL +G D +W++ G + GH + +A
Sbjct: 313 CVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAIS 372
Query: 275 D 275
+
Sbjct: 373 N 373
Score = 31.5 bits (68), Expect = 3.4
Identities = 33/166 (19%), Positives = 66/166 (39%), Gaps = 8/166 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP---RTR 84
I+++D++S +T + S +S F +G ++ T D +IW+ R
Sbjct: 254 IKIWDVTS-QATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGA 312
Query: 85 CQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAID 143
C + Q + V++ D S ++ G + IWD+ + + + D+AI
Sbjct: 313 CVTLMQGHEGSVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAIS 372
Query: 144 PAGKMMAAVNNKGNCYVWSLSGQPPHPVP---KKHITAHSKYALRC 186
K + + + +W++ P+ KK + K RC
Sbjct: 373 NNKKWILSASKDRTMRLWNIEEIDEIPLVIKYKKAVGLKLKQCERC 418
>BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical
protein FLJ25955 protein.
Length = 314
Score = 71.7 bits (168), Expect = 3e-12
Identities = 58/249 (23%), Positives = 101/249 (40%), Gaps = 7/249 (2%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+VNS SP + G + +Y + + + + V F +G +
Sbjct: 23 EVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASAS 82
Query: 68 EDCTARIWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
DCT R+WD R +C ++ + Q V V PD Q+ G + +WD+++ Q
Sbjct: 83 CDCTVRLWD---VARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
+L+ SIQ P +A + +W L P V + + HS + C
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTP-AVSHQALEGHSG-NISC 197
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
S +L + S D + IW+ + +LL +L+ WV AF+ D +L +
Sbjct: 198 LCYSASGLLASGSWDKTIHIWKPTTSSLLIQLKGHV-TWVKSIAFSPDELWLASAGYSRM 256
Query: 247 ARLWNIERG 255
++W+ G
Sbjct: 257 VKVWDCNTG 265
Score = 63.7 bits (148), Expect = 7e-10
Identities = 41/138 (29%), Positives = 65/138 (47%), Gaps = 7/138 (5%)
Query: 137 IQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
+ A P G+M+ + G Y W SGQ + H+ C+FSPD +
Sbjct: 24 VNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLW-----RLGGHTGPVKFCRFSPDGHLF 78
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERG 255
+ S DC+ ++W + LR L+ QR V +F+ DSR L +G D LW+++ G
Sbjct: 79 ASASCDCTVRLWDVARAKCLRVLKGH-QRSVETVSFSPDSRQLASGGWDKRVMLWDVQSG 137
Query: 256 TLEREYCGHQKAITALAF 273
+ R GH+ +I + F
Sbjct: 138 QMLRLLVGHRDSIQSSDF 155
Score = 50.4 bits (115), Expect = 7e-06
Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 9/164 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
VN+ PD ++ G + G ++ W+ ++ Q + ++ P G + A+ +
Sbjct: 24 VNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASC 83
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWAL 214
+W ++ V K H + FSPDS L + D +W +
Sbjct: 84 DCTVRLWDVARAKCLRVLK----GHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 215 LREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGT 256
LR L RD+ + + F+ L TGS DS R+W++ T
Sbjct: 140 LRLLVGHRDS---IQSSDFSPTVNCLATGSWDSTVRIWDLRMVT 180
Score = 43.6 bits (98), Expect = 8e-04
Identities = 45/224 (20%), Positives = 87/224 (38%), Gaps = 13/224 (5%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+RL+D++ A + + ++V V F + + +GG D +WD ++ R
Sbjct: 87 VRLWDVARAKC--LRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRL-- 142
Query: 88 IFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ---NEQLIPEAEASIQDIAIDP 144
+ + + + P + + G + IWDL+ + Q + +I +
Sbjct: 143 LVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCLCYSA 202
Query: 145 AGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
+G + + +K ++W + K H+T A FSPD L +
Sbjct: 203 SGLLASGSWDK-TIHIWKPTTSSLLIQLKGHVTWVKSIA----FSPDELWLASAGYSRMV 257
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
K+W + L L + AFT D + L +G++D R
Sbjct: 258 KVWDCNTGKCLETL-KGVLDVAHTCAFTPDGKILVSGAADQTRR 300
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/226 (19%), Positives = 85/226 (37%), Gaps = 11/226 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+ F +G + TG ED W+ R+ ++ PV PD
Sbjct: 24 VNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLL--WRLGGHTGPVKFCRFSPDGHLFASA 81
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPH 169
+ +WD+ + +++ + S++ ++ P + +A+ +W + SGQ
Sbjct: 82 SCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM-- 139
Query: 170 PVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW--RTSDWALLRELRRDTQRWVW 227
+ + H FSP L T S D + +IW R A+ + +
Sbjct: 140 ---LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNIS 196
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
++ S L +GS D +W +L + GH + ++AF
Sbjct: 197 CLCYSA-SGLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAF 241
>AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ25955 fis, clone TST03904. ).
Length = 415
Score = 70.5 bits (165), Expect = 6e-12
Identities = 55/245 (22%), Positives = 99/245 (40%), Gaps = 11/245 (4%)
Query: 8 QVNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
++ L +P S + A G +L+D+ N + V T S + + F +G + T
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQ--NGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 66 GGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
G D T +WD + + A +++ + D S I+ G +WD +
Sbjct: 237 GSFDHTVVVWDADTGRKVNI--LIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALR 185
+ + I D D GK++A + G ++S + + + K + H +
Sbjct: 295 CVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKC--IAK--LEGHEGEISK 350
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
F+P L+T S D +A+IW L+ L T ++ AF + TGS +
Sbjct: 351 ISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDE-IFSCAFNYKGNIVITGSKGN 409
Query: 246 YARLW 250
R+W
Sbjct: 410 TCRIW 414
Score = 56.4 bits (130), Expect = 1e-07
Identities = 47/231 (20%), Positives = 89/231 (38%), Gaps = 7/231 (3%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + + F T + TG D TA++WD + + A + ++ +
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHS--AEIISLSFNT 229
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+I+ G + +WD T + ++ A I + + ++ + C +W
Sbjct: 230 SGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD 289
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
+ +T H L F ++ T S D +A+I+ + + +L
Sbjct: 290 ATNGKCVAT----LTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE 345
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ +F L TGSSD AR+W+ + G + GH I + AF
Sbjct: 346 GE-ISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTDEIFSCAF 395
Score = 53.6 bits (123), Expect = 7e-07
Identities = 47/250 (18%), Positives = 99/250 (39%), Gaps = 12/250 (4%)
Query: 29 RLYDLSSANPDPVTTFEDISKNVSRVGFQKN-GTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+L+D SA+ + + T E V + F G + TG D T ++W +C
Sbjct: 117 KLWD--SASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCKLWSVETG---KCYH 171
Query: 88 IFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAG 146
F+ A + + +P + + G +WD++ + + A I ++ + +G
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSG 231
Query: 147 KMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKI 206
+ + VW + + H F+ D ++++T S D + K+
Sbjct: 232 DRIITGSFDHTVVVWDADTGRKVNI----LIGHCAEISSASFNWDCSLILTGSMDKTCKL 287
Query: 207 WRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQK 266
W ++ + L + D+ F + + T S+D AR+++ + GH+
Sbjct: 288 WDATNGKCVATLTGHDDE-ILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEG 346
Query: 267 AITALAFKDQ 276
I+ ++F Q
Sbjct: 347 EISKISFNPQ 356
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/225 (20%), Positives = 85/225 (37%), Gaps = 10/225 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVML-HPDQSQIMV 109
++ V K+G+ TG D T ++WD +A + + V A+ +P +I
Sbjct: 95 LTNVALNKSGSCFITGSYDRTCKLWD--SASGEELNTLEGHRNVVYAIAFNNPYGDKIAT 152
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPP 168
G +W ++T + A I ++ +P ++A + +W + +G+
Sbjct: 153 GSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV 212
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
+ + HS + F+ ++T S D + +W + L +
Sbjct: 213 YT-----LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAE-ISS 266
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
A+F D + TGS D +LW+ G GH I F
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCF 311
Score = 37.9 bits (84), Expect = 0.039
Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 2/104 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K + AH + + +T S D + K+W ++ L L + V+ AF
Sbjct: 86 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGH-RNVVYAIAFNN 144
Query: 234 D-SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
+ TGS D +LW++E G + GH I L+F Q
Sbjct: 145 PYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 188
>AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa protein
protein.
Length = 521
Score = 69.3 bits (162), Expect = 1e-11
Identities = 61/245 (24%), Positives = 101/245 (41%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 287 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 344
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 402
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
+ I I P G +A + C VW L + + +P H KF
Sbjct: 403 EDHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----PHQNLVTGVKFE 457
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 458 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATYSYDRTFK 516
Query: 249 LWNIE 253
LW +E
Sbjct: 517 LWMLE 521
Score = 46.8 bits (106), Expect = 8e-05
Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 340
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 341 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 398
Query: 258 EREYCGHQKAITALAF 273
H K I + F
Sbjct: 399 IMFLEDHLKEIYGINF 414
Score = 44.8 bits (101), Expect = 3e-04
Identities = 34/181 (18%), Positives = 67/181 (37%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 342 YDRSWRLWDLEAQE----EILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L D + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 398 CIMFL-EDHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPPHQNLVTGVKF 456
Query: 274 K 274
+
Sbjct: 457 E 457
Score = 39.9 bits (89), Expect = 0.010
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 325 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 383
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 384 LDAFGRVWDL--RTGRCI--MFLEDHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 439
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 440 CVYTIPPH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 240 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 297
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 298 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 357 ILHQEGHSMGVYDIAF 372
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 236 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 269
>U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p
protein.
Length = 520
Score = 68.5 bits (160), Expect = 2e-11
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 286 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 343
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 344 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 401
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 402 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 456
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 457 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 515
Query: 249 LWNIE 253
LW E
Sbjct: 516 LWMAE 520
Score = 51.2 bits (117), Expect = 4e-06
Identities = 46/190 (24%), Positives = 72/190 (37%), Gaps = 17/190 (8%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWD------LKTDQNEQLIPEAEASI--QDIAIDPA 145
P++ P+ + SG+ +W L T + E SI +++DP
Sbjct: 231 PISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTKKEQLHSIPKSTVSLDPK 290
Query: 146 GKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAK 205
+A+ G+ +WSL P I H+ R + P L TT C +
Sbjct: 291 DVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT---CYDR 343
Query: 206 IWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
WR D E+ + V+D AF D TG D++ R+W++ G G
Sbjct: 344 SWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG 403
Query: 264 HQKAITALAF 273
H K I + F
Sbjct: 404 HLKEIYGINF 413
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 281 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 340
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 341 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 396
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 397 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 455
Query: 274 K 274
+
Sbjct: 456 E 456
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 324 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 382
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 383 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 438
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 439 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 496
>BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 68.5 bits (160), Expect = 2e-11
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 287 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 344
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 402
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 403 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 457
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 458 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 516
Query: 249 LWNIE 253
LW E
Sbjct: 517 LWMAE 521
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 340
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 341 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 398
Query: 258 EREYCGHQKAITALAF 273
GH K I + F
Sbjct: 399 IMFLEGHLKEIYGINF 414
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 342 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 398 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 456
Query: 274 K 274
+
Sbjct: 457 E 457
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 325 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 383
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 384 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 439
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 440 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 240 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 297
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 298 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 357 ILHQEGHSMGVYDIAF 372
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 236 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 269
>BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 68.5 bits (160), Expect = 2e-11
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 288 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 345
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 346 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 403
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 404 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 458
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 459 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 517
Query: 249 LWNIE 253
LW E
Sbjct: 518 LWMAE 522
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 341
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 342 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 399
Query: 258 EREYCGHQKAITALAF 273
GH K I + F
Sbjct: 400 IMFLEGHLKEIYGINF 415
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 283 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 342
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 343 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 398
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 399 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 457
Query: 274 K 274
+
Sbjct: 458 E 458
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 326 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 384
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 385 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 440
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 441 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 498
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 241 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 298
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 299 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 357
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 358 ILHQEGHSMGVYDIAF 373
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 237 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 270
>AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6
snRNP-specific spliceosomal protein protein.
Length = 521
Score = 68.5 bits (160), Expect = 2e-11
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 287 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 344
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 402
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 403 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 457
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 458 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 516
Query: 249 LWNIE 253
LW E
Sbjct: 517 LWMAE 521
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 340
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 341 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 398
Query: 258 EREYCGHQKAITALAF 273
GH K I + F
Sbjct: 399 IMFLEGHLKEIYGINF 414
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 342 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 398 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 456
Query: 274 K 274
+
Sbjct: 457 E 457
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 325 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 383
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 384 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 439
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 440 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 240 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 297
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 298 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 357 ILHQEGHSMGVYDIAF 372
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 236 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 269
>AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 68.5 bits (160), Expect = 2e-11
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 287 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 344
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 402
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 403 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 457
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 458 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 516
Query: 249 LWNIE 253
LW E
Sbjct: 517 LWMAE 521
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 340
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 341 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 398
Query: 258 EREYCGHQKAITALAF 273
GH K I + F
Sbjct: 399 IMFLEGHLKEIYGINF 414
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 342 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 398 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 456
Query: 274 K 274
+
Sbjct: 457 E 457
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 325 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 383
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 384 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 439
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 440 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 240 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 297
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 298 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 357 ILHQEGHSMGVYDIAF 372
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 236 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 269
>AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 68.5 bits (160), Expect = 2e-11
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 288 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 345
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 346 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 403
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 404 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 458
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 459 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 517
Query: 249 LWNIE 253
LW E
Sbjct: 518 LWMAE 522
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 341
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 342 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 399
Query: 258 EREYCGHQKAITALAF 273
GH K I + F
Sbjct: 400 IMFLEGHLKEIYGINF 415
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 283 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 342
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 343 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 398
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 399 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 457
Query: 274 K 274
+
Sbjct: 458 E 458
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 326 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 384
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 385 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 440
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 441 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 498
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 241 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 298
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 299 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 357
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 358 ILHQEGHSMGVYDIAF 373
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 237 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 270
>AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear
ribonucleoprotein hPrp4 protein.
Length = 522
Score = 68.5 bits (160), Expect = 2e-11
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 288 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 345
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 346 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 403
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 404 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 458
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 459 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 517
Query: 249 LWNIE 253
LW E
Sbjct: 518 LWMAE 522
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 341
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 342 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 399
Query: 258 EREYCGHQKAITALAF 273
GH K I + F
Sbjct: 400 IMFLEGHLKEIYGINF 415
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 283 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 342
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 343 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 398
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 399 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 457
Query: 274 K 274
+
Sbjct: 458 E 458
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 326 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 384
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 385 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 440
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 441 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 498
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 241 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 298
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 299 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 357
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 358 ILHQEGHSMGVYDIAF 373
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 237 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 270
>AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant
protein.
Length = 537
Score = 68.5 bits (160), Expect = 2e-11
Identities = 62/245 (25%), Positives = 100/245 (40%), Gaps = 12/245 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 303 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 360
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 361 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 418
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 419 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 473
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 474 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 532
Query: 249 LWNIE 253
LW E
Sbjct: 533 LWMAE 537
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 302 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 356
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 357 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 414
Query: 258 EREYCGHQKAITALAF 273
GH K I + F
Sbjct: 415 IMFLEGHLKEIYGINF 430
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 298 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 357
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 358 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 413
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 414 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 472
Query: 274 K 274
+
Sbjct: 473 E 473
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 341 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 399
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 400 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 455
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 456 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 513
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 256 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 313
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 314 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 372
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 373 ILHQEGHSMGVYDIAF 388
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 252 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 285
>BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 4 protein.
Length = 340
Score = 68.1 bits (159), Expect = 3e-11
Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 2/171 (1%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D ++ Q G + IWD T IP + + A P+G +A C +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L + + + + H+ Y C+F DS +VT+SGD + +W + A
Sbjct: 126 LKTREGNVRVSRELPGHTGYLSCCRFLDDS-QIVTSSGDTTCALW-DIETAQQTTTFTGH 183
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V + + D R +G+ D+ ++LW+I G + + GH I A++F
Sbjct: 184 SGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSF 234
Score = 51.2 bits (117), Expect = 4e-06
Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 16/199 (8%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ + +V ++G L+D+ +A TTF S +V + + +G D +++
Sbjct: 152 LDDSQIVTSSGDTTCALWDIETAQQ--TTTFTGHSGDVMSLSLSPDMRTFVSGACDASSK 209
Query: 74 IWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F + +NAV P+ G ++DL+ DQ L
Sbjct: 210 LWDIRDG---MCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCKFS 189
I +A +G+++ A + NC VW +L G + + A + C
Sbjct: 267 DNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGD------RAGVLAGHDNRVSCLGV 320
Query: 190 PDSTMLVTT-SGDCSAKIW 207
D M V T S D +IW
Sbjct: 321 TDDGMAVATGSWDSFLRIW 339
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/174 (18%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D SQI+ +WD++T Q + +++ P + + + +W
Sbjct: 153 DDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D LL +
Sbjct: 213 IRDG----MCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTD 322
Score = 40.3 bits (90), Expect = 0.007
Identities = 42/192 (21%), Positives = 68/192 (35%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD A +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETAQQTTT--FTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q + I ++ P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRAD-------QELLLYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W T L R V T D +
Sbjct: 270 ICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ R+WN
Sbjct: 329 TGSWDSFLRIWN 340
Score = 33.5 bits (73), Expect = 0.83
Identities = 23/114 (20%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + + ++I ++ V F K+G + G
Sbjct: 229 INAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWDTLKGDRAGV--LAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
Score = 32.3 bits (70), Expect = 1.9
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 5/120 (4%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL +SP + V+ A +L+D+ +F +++ V F NG TG
Sbjct: 187 VMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQ--SFTGHVSDINAVSFFPNGYAFATG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD-LKTDQ 125
+D T R++D RA + + +V ++ G ++WD LK D+
Sbjct: 245 SDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDR 304
>AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide binding
protein beta subunit 4 protein.
Length = 340
Score = 68.1 bits (159), Expect = 3e-11
Identities = 42/171 (24%), Positives = 75/171 (43%), Gaps = 2/171 (1%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D ++ Q G + IWD T IP + + A P+G +A C +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L + + + + H+ Y C+F DS +VT+SGD + +W + A
Sbjct: 126 LKTREGNVRVSRELPGHTGYLSCCRFLDDS-QIVTSSGDTTCALW-DIETAQQTTTFTGH 183
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V + + D R +G+ D+ ++LW+I G + + GH I A++F
Sbjct: 184 SGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSF 234
Score = 51.2 bits (117), Expect = 4e-06
Identities = 47/199 (23%), Positives = 82/199 (41%), Gaps = 16/199 (8%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ + +V ++G L+D+ +A TTF S +V + + +G D +++
Sbjct: 152 LDDSQIVTSSGDTTCALWDIETAQQ--TTTFTGHSGDVMSLSLSPDMRTFVSGACDASSK 209
Query: 74 IWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F + +NAV P+ G ++DL+ DQ L
Sbjct: 210 LWDIRDG---MCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCKFS 189
I +A +G+++ A + NC VW +L G + + A + C
Sbjct: 267 DNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGD------RAGVLAGHDNRVSCLGV 320
Query: 190 PDSTMLVTT-SGDCSAKIW 207
D M V T S D +IW
Sbjct: 321 TDDGMAVATGSWDSFLRIW 339
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/174 (18%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D SQI+ +WD++T Q + +++ P + + + +W
Sbjct: 153 DDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D LL +
Sbjct: 213 IRDG----MCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTD 322
Score = 40.3 bits (90), Expect = 0.007
Identities = 42/192 (21%), Positives = 68/192 (35%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD A +T V ++ L PD + G +WD++
Sbjct: 159 TSSGDTTCALWDIETAQQTTT--FTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDG 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q + I ++ P G A ++ C ++ L + + +S +
Sbjct: 217 MCRQSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFDLRAD-------QELLLYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W T L R V T D +
Sbjct: 270 ICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ R+WN
Sbjct: 329 TGSWDSFLRIWN 340
Score = 33.5 bits (73), Expect = 0.83
Identities = 23/114 (20%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + + ++I ++ V F K+G + G
Sbjct: 229 INAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAG 288
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD R + V+ + + D + G + IW+
Sbjct: 289 YDDFNCNVWDTLKGDRAGV--LAGHDNRVSCLGVTDDGMAVATGSWDSFLRIWN 340
Score = 32.3 bits (70), Expect = 1.9
Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 5/120 (4%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL +SP + V+ A +L+D+ +F +++ V F NG TG
Sbjct: 187 VMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQ--SFTGHVSDINAVSFFPNGYAFATG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD-LKTDQ 125
+D T R++D RA + + +V ++ G ++WD LK D+
Sbjct: 245 SDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDR 304
>Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats
containing protein protein.
Length = 569
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 282 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 338 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 392
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 448
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 449 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 483
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 255 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 311
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 312 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 357
>CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein.
Length = 521
Score = 67.7 bits (158), Expect = 4e-11
Identities = 61/242 (25%), Positives = 99/242 (40%), Gaps = 12/242 (4%)
Query: 11 SLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
SL+ ++ + A ++L+ L S +PV E + V+RV + +G ++ T D
Sbjct: 287 SLDPKDVNLASCAADGSVKLWSLDS--DEPVADIEGHTVRVARVMWHPSGRFLGTTCYDR 344
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
+ R+WD A Q+ + V + H D S G +WDL+T + +
Sbjct: 345 SWRLWDLEAQEEILHQEGHSMG--VYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 402
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFS 189
I I P G +A + C VW L + + +P AH KF
Sbjct: 403 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIP-----AHQNLVTGVKFE 457
Query: 190 P-DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
P L+T + D +AKIW W+ L+ L + V + D + + T S D +
Sbjct: 458 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGK-VMGLDISSDGQLIATCSYDRTFK 516
Query: 249 LW 250
LW
Sbjct: 517 LW 518
Score = 49.6 bits (113), Expect = 1e-05
Identities = 36/136 (26%), Positives = 55/136 (40%), Gaps = 9/136 (6%)
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+++DP +A+ G+ +WSL P I H+ R + P L TT
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEP----VADIEGHTVRVARVMWHPSGRFLGTT- 340
Query: 200 GDCSAKIWRTSDWALLREL--RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
C + WR D E+ + V+D AF D TG D++ R+W++ G
Sbjct: 341 --CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRC 398
Query: 258 EREYCGHQKAITALAF 273
GH K I + F
Sbjct: 399 IMFLEGHLKEIYGINF 414
Score = 44.0 bits (99), Expect = 6e-04
Identities = 33/181 (18%), Positives = 66/181 (36%), Gaps = 5/181 (2%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
P + V L P + G + +W L +D+ I + + P+G+ +
Sbjct: 282 PKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTC 341
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ +W L Q H HS F D ++ T D ++W
Sbjct: 342 YDRSWRLWDLEAQEEI----LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 397
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L + ++ F+ + + TGS D+ ++W++ + HQ +T + F
Sbjct: 398 CIMFLEGHLKE-IYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKF 456
Query: 274 K 274
+
Sbjct: 457 E 457
Score = 41.1 bits (92), Expect = 0.004
Identities = 43/179 (24%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEA-SIQDIAIDPAGKMMAAVN 153
V VM HP + +WDL+ Q E L E + + DIA G +
Sbjct: 325 VARVMWHPSGRFLGTTCYDRSWRLWDLEA-QEEILHQEGHSMGVYDIAFHQDGSLAGTGG 383
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWA 213
VW L + + + H K FSP+ + T SGD + K+W
Sbjct: 384 LDAFGRVWDL--RTGRCI--MFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRR 439
Query: 214 LLRELRRDTQRWVWDAAFT-LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ + Q V F + FL TG+ D+ A++W + + GH+ + L
Sbjct: 440 CVYTIPAH-QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGL 497
Score = 34.3 bits (75), Expect = 0.48
Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 9/136 (6%)
Query: 144 PAGKMMAAVNNKGNCYVWS------LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVT 197
P KM+A G C +WS L H I H K + P L +
Sbjct: 240 PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTV--SLDPKDVNLAS 297
Query: 198 TSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
+ D S K+W + ++ T R V + RFL T D RLW++E
Sbjct: 298 CAADGSVKLWSLDSDEPVADIEGHTVR-VARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356
Query: 258 EREYCGHQKAITALAF 273
GH + +AF
Sbjct: 357 ILHQEGHSMGVYDIAF 372
Score = 31.9 bits (69), Expect = 2.5
Identities = 15/34 (44%), Positives = 17/34 (50%)
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
C FSP+S ML T K+W D LL LR
Sbjct: 236 CHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLR 269
>BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 318 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 374 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 428
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 484
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 485 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 519
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 291 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 347
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 348 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 393
>AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 282 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 338 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 392
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 448
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 449 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 483
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 255 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 311
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 312 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 357
>AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 318 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 374 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 428
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 484
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 485 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 519
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 291 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 347
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 348 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 393
>AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 282 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 338 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 392
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 448
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 449 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 483
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 255 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 311
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 312 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 357
>AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 318 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 374 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 428
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 484
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 485 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 519
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 291 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 347
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 348 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 393
>AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat
containing protein.
Length = 569
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 282 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 338 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 392
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 448
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 449 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 483
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 255 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 311
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 312 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 357
>AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat
containing protein.
Length = 605
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 318 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 374 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 428
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 484
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 485 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 519
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 291 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 347
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 348 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 393
>AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A
protein.
Length = 569
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 282 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 337
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 338 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 392
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 393 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 448
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 449 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 483
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 255 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 311
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 312 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 357
>AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant
E3RS-IkappaB protein.
Length = 605
Score = 67.7 bits (158), Expect = 4e-11
Identities = 53/215 (24%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D T +IWD C++I + + L D+ I+ G + +WD+ T
Sbjct: 318 SGLRDNTIKIWDKNTL---ECKRILTGHTG-SVLCLQYDERVIITGSSDSTVRVWDVNTG 373
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + MM + + VW ++ P + + + + A
Sbjct: 374 EMLNTLIHHCEAVLH---LRFNNGMMVTCSKDRSIAVWDMAS--PTDITLRRVLVGHRAA 428
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 429 VNV-VDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 484
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 485 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 519
Score = 39.5 bits (88), Expect = 0.013
Identities = 27/107 (25%), Positives = 45/107 (42%), Gaps = 4/107 (3%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + + H + + + C D +V+ D + KIW + R L T +
Sbjct: 291 HSLQRIHCRSETSKGVYC-LQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVL-- 347
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
D R + TGSSDS R+W++ G + H +A+ L F +
Sbjct: 348 -CLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNN 393
>M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transducin
beta-2 subunit mRNA, complete cds. ).
Length = 340
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + D R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 34.7 bits (76), Expect = 0.36
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + D R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 34.7 bits (76), Expect = 0.36
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + D R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 34.7 bits (76), Expect = 0.36
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + D R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 34.7 bits (76), Expect = 0.36
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + D R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 34.7 bits (76), Expect = 0.36
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + D R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 34.7 bits (76), Expect = 0.36
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide binding
protein beta 2 protein.
Length = 340
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + D R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 34.7 bits (76), Expect = 0.36
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 66.5 bits (155), Expect = 1e-10
Identities = 41/181 (22%), Positives = 75/181 (41%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A P+G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + D R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 38.3 bits (85), Expect = 0.029
Identities = 42/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 34.7 bits (76), Expect = 0.36
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD repeat
protein protein.
Length = 631
Score = 64.9 bits (151), Expect = 3e-10
Identities = 54/237 (22%), Positives = 96/237 (40%), Gaps = 10/237 (4%)
Query: 15 SPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARI 74
S + ++G ++L+DL + D + TFE S+ V + G ++ + D T++I
Sbjct: 405 SGDKLATSSGDTTVKLWDLCTG--DCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKI 462
Query: 75 WDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAE 134
WD + R RC ++ VN++ P + ++ + IWD +T EQ +
Sbjct: 463 WDVNSE-RCRCT-LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHM 520
Query: 135 ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTM 194
SI D DP G M+A+ + G +W +P I F +
Sbjct: 521 HSINDAIFDPRGHMIASCDACGVTKLWDFR----KLLPIVSIDIGPSPGNEVNFDSSGRV 576
Query: 195 LVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
L SG+ + + + + + + F+ D LF+G SD R W+
Sbjct: 577 LAQASGNGVIHLLDLKSGEIHKLMGHENE--AHTVVFSHDGEILFSGGSDGTVRTWS 631
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 156 GNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWR--TSDWA 213
G +W + G P V H+ + C F P L T+SGD + K+W T D
Sbjct: 371 GEDRLWKVLGLPKCNVLLTGF-GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCI 429
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L E R VW + F+ + S D +++W++ GH ++ ++ F
Sbjct: 430 LTFE---GHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEF 486
Score = 33.9 bits (74), Expect = 0.63
Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 1/95 (1%)
Query: 179 HSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
HS+ C + + ++S D ++KIW + L T V F S L
Sbjct: 435 HSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDS-VNSIEFFPFSNTL 493
Query: 239 FTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
T S+D +W+ G E+ GH +I F
Sbjct: 494 LTSSADKTLSIWDARTGICEQSLYGHMHSINDAIF 528
>AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein.
Length = 631
Score = 64.9 bits (151), Expect = 3e-10
Identities = 54/237 (22%), Positives = 96/237 (40%), Gaps = 10/237 (4%)
Query: 15 SPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARI 74
S + ++G ++L+DL + D + TFE S+ V + G ++ + D T++I
Sbjct: 405 SGDKLATSSGDTTVKLWDLCTG--DCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKI 462
Query: 75 WDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAE 134
WD + R RC ++ VN++ P + ++ + IWD +T EQ +
Sbjct: 463 WDVNSE-RCRCT-LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHM 520
Query: 135 ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTM 194
SI D DP G M+A+ + G +W +P I F +
Sbjct: 521 HSINDAIFDPRGHMIASCDACGVTKLWDFR----KLLPIVSIDIGPSPGNEVNFDSSGRV 576
Query: 195 LVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
L SG+ + + + + + + F+ D LF+G SD R W+
Sbjct: 577 LAQASGNGVIHLLDLKSGEIHKLMGHENE--AHTVVFSHDGEILFSGGSDGTVRTWS 631
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 6/120 (5%)
Query: 156 GNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWR--TSDWA 213
G +W + G P V H+ + C F P L T+SGD + K+W T D
Sbjct: 371 GEDRLWKVLGLPKCNVLLTGF-GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTGDCI 429
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L E R VW + F+ + S D +++W++ GH ++ ++ F
Sbjct: 430 LTFE---GHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEF 486
Score = 33.9 bits (74), Expect = 0.63
Identities = 24/95 (25%), Positives = 37/95 (38%), Gaps = 1/95 (1%)
Query: 179 HSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
HS+ C + + ++S D ++KIW + L T V F S L
Sbjct: 435 HSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDS-VNSIEFFPFSNTL 493
Query: 239 FTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
T S+D +W+ G E+ GH +I F
Sbjct: 494 LTSSADKTLSIWDARTGICEQSLYGHMHSINDAIF 528
>BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like
1Y-linked protein.
Length = 522
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/217 (24%), Positives = 87/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 284 WNKKGNYVLSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNMTFASCSTDM-C 340
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D + + I DP+G ++A+ ++ +WS+
Sbjct: 341 IHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMK----QDACVHD 396
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AHSK K+SP S ML + S D + ++W L + Q V
Sbjct: 397 LQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH-QEPV 455
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D Y +WN + G+L Y G
Sbjct: 456 YSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492
Score = 63.3 bits (147), Expect = 9e-10
Identities = 58/235 (24%), Positives = 98/235 (41%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + +GT + G D ARIW + Q + P+ A+ + + +
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENG---NLASTLGQHKGPIFALKWNKKGNYV 291
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D M A + C +V L
Sbjct: 292 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNMTFASCSTDMCIHVCRLGCD 349
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQ--- 223
HPV K H+ K+ P +L + S D + KIW A + +L+ ++
Sbjct: 350 --HPV--KTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 224 --RWVWDAAFTLD---SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + S L + S DS RLW++E+G HQ+ + ++AF
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF 460
Score = 40.3 bits (90), Expect = 0.007
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 411 PTGPATSNPN-SSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLAS 469
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 470 GSFDKYVHIWNTQSGSLVH 488
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + D L GS D +AR+W E G L H+ I AL
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIFAL 282
>BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like
1Y-linked protein.
Length = 522
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/217 (24%), Positives = 87/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 284 WNKKGNYVLSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNMTFASCSTDM-C 340
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D + + I DP+G ++A+ ++ +WS+
Sbjct: 341 IHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMK----QDACVHD 396
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AHSK K+SP S ML + S D + ++W L + Q V
Sbjct: 397 LQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH-QEPV 455
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D Y +WN + G+L Y G
Sbjct: 456 YSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492
Score = 63.3 bits (147), Expect = 9e-10
Identities = 58/235 (24%), Positives = 98/235 (41%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + +GT + G D ARIW + Q + P+ A+ + + +
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENG---NLASTLGQHKGPIFALKWNKKGNYV 291
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D M A + C +V L
Sbjct: 292 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNMTFASCSTDMCIHVCRLGCD 349
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQ--- 223
HPV K H+ K+ P +L + S D + KIW A + +L+ ++
Sbjct: 350 --HPV--KTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 224 --RWVWDAAFTLD---SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + S L + S DS RLW++E+G HQ+ + ++AF
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF 460
Score = 40.3 bits (90), Expect = 0.007
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 411 PTGPATSNPN-SSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLAS 469
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 470 GSFDKYVHIWNTQSGSLVH 488
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + D L GS D +AR+W E G L H+ I AL
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIFAL 282
>BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein.
Length = 571
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/237 (22%), Positives = 95/237 (40%), Gaps = 10/237 (4%)
Query: 15 SPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARI 74
S + ++G ++L+DL D + TFE S+ V + G ++ + D T++I
Sbjct: 345 SGDKLATSSGDTTVKLWDLCKG--DCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKI 402
Query: 75 WDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAE 134
WD + R RC ++ VN++ P + ++ + IWD +T EQ +
Sbjct: 403 WDVNSE-RCRCT-LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHM 460
Query: 135 ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTM 194
SI D DP G M+A+ + G +W +P I F +
Sbjct: 461 HSINDAIFDPRGHMIASCDACGVTKLWDFR----KLLPIVSIDIGPSPGNEVNFDSSGRV 516
Query: 195 LVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
L SG+ + + + + + + F+ D LF+G SD R W+
Sbjct: 517 LAQASGNGVIHLLDLKSGEIHKLMGHENE--AHTVVFSHDGEILFSGGSDGTVRTWS 571
Score = 43.6 bits (98), Expect = 8e-04
Identities = 26/118 (22%), Positives = 47/118 (39%), Gaps = 2/118 (1%)
Query: 156 GNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALL 215
G +W + G P V H+ + C F P L T+SGD + K+W +
Sbjct: 311 GEDRLWKVLGLPKCNVLLTGF-GHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKGDCI 369
Query: 216 RELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ R VW + F+ + S D +++W++ GH ++ ++ F
Sbjct: 370 LTFEGHS-RAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEF 426
Score = 35.9 bits (79), Expect = 0.16
Identities = 40/192 (20%), Positives = 71/192 (36%), Gaps = 8/192 (4%)
Query: 84 RCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-IQDIA 141
+ + IF++ + PV+ V +HP + ++ + + + L N L + D
Sbjct: 283 KLKNIFRLHELPVSCVSMHPHKDILVSCGEDRLWKVLGLPKC-NVLLTGFGHTDWLSDCC 341
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
P+G +A + +W L HS+ C + + ++S D
Sbjct: 342 FHPSGDKLATSSGDTTVKLWDLCKGDCILT----FEGHSRAVWSCTWHSCGNFVASSSLD 397
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
++KIW + L T V F S L T S+D +W+ G E+
Sbjct: 398 KTSKIWDVNSERCRCTLYGHTDS-VNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSL 456
Query: 262 CGHQKAITALAF 273
GH +I F
Sbjct: 457 YGHMHSINDAIF 468
>AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymerase
II, p300/CBP-associated factor (PCAF)-associated facto
protein.
Length = 589
Score = 64.5 bits (150), Expect = 4e-10
Identities = 68/268 (25%), Positives = 109/268 (40%), Gaps = 23/268 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N+ EISP S + AAGF + I+L+ L S E +VSR+ + +
Sbjct: 271 LNTAEISPDSKLLAAGFDNSCIKLWSLRSKK----LKSEPHQVDVSRIHLACD---ILEE 323
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D R C PV + D S ++ + I WDL + N
Sbjct: 324 EDDEDDNAGTEMKILRGHC-------GPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTN 376
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
L + D+ I P A+ ++ +WS P + H+ + C
Sbjct: 377 TVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLAD-----VDC 431
Query: 187 -KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
KF P+S L T S D + ++W +R L + V AF+ + ++L + D
Sbjct: 432 VKFHPNSNYLATGSTDKTVRLWSAQQGNSVR-LFTGHRGPVLSLAFSPNGKYLASAGEDQ 490
Query: 246 YARLWNIERGTLEREYCGHQKAITALAF 273
+LW++ GTL +E GH IT+L F
Sbjct: 491 RLKLWDLASGTLYKELRGHTDNITSLTF 518
Score = 60.1 bits (139), Expect = 8e-09
Identities = 35/144 (24%), Positives = 63/144 (43%), Gaps = 8/144 (5%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
+G D TAR+W + RT +I+ A V+ V HP+ + + G + +W +
Sbjct: 401 SGSHDRTARLW---SFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 457
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ +L + +A P GK +A+ +W L+ + K + H+
Sbjct: 458 GNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLY----KELRGHTDNI 513
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIW 207
FSPDS ++ + S D S ++W
Sbjct: 514 TSLTFSPDSGLIASASMDNSVRVW 537
Score = 43.6 bits (98), Expect = 8e-04
Identities = 34/153 (22%), Positives = 64/153 (41%), Gaps = 4/153 (2%)
Query: 12 LEISPTSMVAAAGFQHIRLYDLSSANPD-PVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
L+ISP S+ A+G H R L S + P+ + +V V F N ++ TG D
Sbjct: 390 LDISPYSLYFASG-SHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDK 448
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
T R+W + R + PV ++ P+ + + + +WDL + + +
Sbjct: 449 TVRLWSAQQGNSVRL--FTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKEL 506
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL 163
+I + P ++A+ + + VW +
Sbjct: 507 RGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539
Score = 37.1 bits (82), Expect = 0.068
Identities = 26/116 (22%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ ++ P S A G + +RL+ N V F V + F NG ++ +
Sbjct: 429 VDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS--VRLFTGHRGPVLSLAFSPNGKYLASA 486
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLK 122
GED ++WD A T +++ + ++ PD I + +WD++
Sbjct: 487 GEDQRLKLWD--LASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR 540
>AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/217 (24%), Positives = 87/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 284 WNKKGNYVLSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNMTFASCSTDM-C 340
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D + + I DP+G ++A+ ++ +WS+
Sbjct: 341 IHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMK----QDACVHD 396
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AHSK K+SP S ML + S D + ++W L + Q V
Sbjct: 397 LQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH-QEPV 455
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D Y +WN + G+L Y G
Sbjct: 456 YSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492
Score = 63.3 bits (147), Expect = 9e-10
Identities = 58/235 (24%), Positives = 98/235 (41%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + +GT + G D ARIW + Q + P+ A+ + + +
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENG---NLASTLGQHKGPIFALKWNKKGNYV 291
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D M A + C +V L
Sbjct: 292 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNMTFASCSTDMCIHVCRLGCD 349
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQ--- 223
HPV K H+ K+ P +L + S D + KIW A + +L+ ++
Sbjct: 350 --HPV--KTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 224 --RWVWDAAFTLD---SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + S L + S DS RLW++E+G HQ+ + ++AF
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF 460
Score = 40.3 bits (90), Expect = 0.007
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 411 PTGPATSNPN-SSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLAS 469
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 470 GSFDKYVHIWNTQSGSLVH 488
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + D L GS D +AR+W E G L H+ I AL
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIFAL 282
>AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/217 (24%), Positives = 87/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 284 WNKKGNYVLSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNMTFASCSTDM-C 340
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D + + I DP+G ++A+ ++ +WS+
Sbjct: 341 IHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMK----QDACVHD 396
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AHSK K+SP S ML + S D + ++W L + Q V
Sbjct: 397 LQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH-QEPV 455
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D Y +WN + G+L Y G
Sbjct: 456 YSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492
Score = 63.3 bits (147), Expect = 9e-10
Identities = 58/235 (24%), Positives = 98/235 (41%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + +GT + G D ARIW + Q + P+ A+ + + +
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENG---NLASTLGQHKGPIFALKWNKKGNYV 291
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D M A + C +V L
Sbjct: 292 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNMTFASCSTDMCIHVCRLGCD 349
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQ--- 223
HPV K H+ K+ P +L + S D + KIW A + +L+ ++
Sbjct: 350 --HPV--KTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 224 --RWVWDAAFTLD---SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + S L + S DS RLW++E+G HQ+ + ++AF
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF 460
Score = 40.3 bits (90), Expect = 0.007
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 411 PTGPATSNPN-SSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLAS 469
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 470 GSFDKYVHIWNTQSGSLVH 488
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + D L GS D +AR+W E G L H+ I AL
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIFAL 282
>AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1
protein.
Length = 522
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/217 (24%), Positives = 87/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 284 WNKKGNYVLSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNMTFASCSTDM-C 340
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D + + I DP+G ++A+ ++ +WS+
Sbjct: 341 IHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMK----QDACVHD 396
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AHSK K+SP S ML + S D + ++W L + Q V
Sbjct: 397 LQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKH-QEPV 455
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D Y +WN + G+L Y G
Sbjct: 456 YSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492
Score = 63.3 bits (147), Expect = 9e-10
Identities = 58/235 (24%), Positives = 98/235 (41%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + +GT + G D ARIW + Q + P+ A+ + + +
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWTENG---NLASTLGQHKGPIFALKWNKKGNYV 291
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D M A + C +V L
Sbjct: 292 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNMTFASCSTDMCIHVCRLGCD 349
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQ--- 223
HPV K H+ K+ P +L + S D + KIW A + +L+ ++
Sbjct: 350 --HPV--KTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIY 405
Query: 224 --RWVWDAAFTLD---SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + S L + S DS RLW++E+G HQ+ + ++AF
Sbjct: 406 TIKWSPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAF 460
Score = 40.3 bits (90), Expect = 0.007
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 351 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWS 410
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 411 PTGPATSNPN-SSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLAS 469
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 470 GSFDKYVHIWNTQSGSLVH 488
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 46/109 (42%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 175 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 234
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + D L GS D +AR+W E G L H+ I AL
Sbjct: 235 NKDVTSLDWNSDGTLLAMGSYDGFARIWT-ENGNLASTLGQHKGPIFAL 282
>AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor 65
beta protein.
Length = 589
Score = 64.5 bits (150), Expect = 4e-10
Identities = 68/268 (25%), Positives = 109/268 (40%), Gaps = 23/268 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N+ EISP S + AAGF + I+L+ L S E +VSR+ + +
Sbjct: 271 LNTAEISPDSKLLAAGFDNSCIKLWSLRSKK----LKSEPHQVDVSRIHLACD---ILEE 323
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D R C PV + D S ++ + I WDL + N
Sbjct: 324 EDDEDDNAGTEMKILRGHC-------GPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTN 376
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
L + D+ I P A+ ++ +WS P + H+ + C
Sbjct: 377 TVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHLAD-----VDC 431
Query: 187 -KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
KF P+S L T S D + ++W +R L + V AF+ + ++L + D
Sbjct: 432 VKFHPNSNYLATGSTDKTVRLWSAQQGNSVR-LFTGHRGPVLSLAFSPNGKYLASAGEDQ 490
Query: 246 YARLWNIERGTLEREYCGHQKAITALAF 273
+LW++ GTL +E GH IT+L F
Sbjct: 491 RLKLWDLASGTLYKELRGHTDNITSLTF 518
Score = 60.1 bits (139), Expect = 8e-09
Identities = 35/144 (24%), Positives = 63/144 (43%), Gaps = 8/144 (5%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
+G D TAR+W + RT +I+ A V+ V HP+ + + G + +W +
Sbjct: 401 SGSHDRTARLW---SFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 457
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ +L + +A P GK +A+ +W L+ + K + H+
Sbjct: 458 GNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLY----KELRGHTDNI 513
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIW 207
FSPDS ++ + S D S ++W
Sbjct: 514 TSLTFSPDSGLIASASMDNSVRVW 537
Score = 43.6 bits (98), Expect = 8e-04
Identities = 34/153 (22%), Positives = 64/153 (41%), Gaps = 4/153 (2%)
Query: 12 LEISPTSMVAAAGFQHIRLYDLSSANPD-PVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
L+ISP S+ A+G H R L S + P+ + +V V F N ++ TG D
Sbjct: 390 LDISPYSLYFASG-SHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDK 448
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
T R+W + R + PV ++ P+ + + + +WDL + + +
Sbjct: 449 TVRLWSAQQGNSVRL--FTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKEL 506
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL 163
+I + P ++A+ + + VW +
Sbjct: 507 RGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 539
Score = 37.1 bits (82), Expect = 0.068
Identities = 26/116 (22%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ ++ P S A G + +RL+ N V F V + F NG ++ +
Sbjct: 429 VDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS--VRLFTGHRGPVLSLAFSPNGKYLASA 486
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLK 122
GED ++WD A T +++ + ++ PD I + +WD++
Sbjct: 487 GEDQRLKLWD--LASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR 540
>BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 63.3 bits (147), Expect = 9e-10
Identities = 47/226 (20%), Positives = 101/226 (44%), Gaps = 11/226 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMV 109
+S V + + + + +D T +IWD + +C K + + V +P + I+
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSG---KCLKTLKGHSNYVFCCNFNPQSNLIVS 146
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPP 168
G + IWD+KT + + +P + + + G ++ + + G C +W + SGQ
Sbjct: 147 GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-- 204
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVW 227
K I + KFSP+ ++ + D + K+W S L+ +++
Sbjct: 205 --CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 228 DAAFTLDS-RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
A F++ +++ +GS D+ +WN++ + ++ GH + + A
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA 308
Score = 60.1 bits (139), Expect = 8e-09
Identities = 46/220 (20%), Positives = 97/220 (44%), Gaps = 10/220 (4%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAVMLHPDQSQ 106
+K VS V F NG W+ + D +IW A + +K I + ++ V D +
Sbjct: 45 TKAVSSVKFSPNGEWLASSSADKLIKIW---GAYDGKFEKTISGHKLGISDVAWSSDSNL 101
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SG 165
++ + IWD+ + + + + + +P ++ + + + +W + +G
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 166 QPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRW 225
+ +P AHS F+ D +++V++S D +IW T+ L+ L D
Sbjct: 162 KCLKTLP-----AHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQ 265
V F+ + +++ + D+ +LW+ +G + Y GH+
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK 256
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 173 KKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFT 232
+K I+ H +S DS +LV+ S D + KIW S L+ L+ + +V+ F
Sbjct: 80 EKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSN-YVFCCNFN 138
Query: 233 LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
S + +GS D R+W+++ G + H ++A+ F
Sbjct: 139 PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179
Score = 48.8 bits (111), Expect = 2e-05
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 1/109 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P+ K + H+K KFSP+ L ++S D KIW D + + + +
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH-KLGIS 91
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
D A++ DS L + S D ++W++ G + GH + F Q
Sbjct: 92 DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQ 140
Score = 33.9 bits (74), Expect = 0.63
Identities = 32/151 (21%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Query: 18 SMVAAAGFQHI-RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD 76
S++ ++ + + R++D +S T +D + VS V F NG ++ D T ++WD
Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLK-TLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 242
Query: 77 PRAAPRTRCQKIF----QVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+ +C K + + + A I+ G + +++IW+L+T + Q +
Sbjct: 243 ---YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG 299
Query: 133 AEASIQDIAIDPAGKMM--AAVNNKGNCYVW 161
+ A P ++ AA+ N +W
Sbjct: 300 HTDVVISTACHPTENIIASAALENDKTIKLW 330
>BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 63.3 bits (147), Expect = 9e-10
Identities = 47/226 (20%), Positives = 101/226 (44%), Gaps = 11/226 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMV 109
+S V + + + + +D T +IWD + +C K + + V +P + I+
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSG---KCLKTLKGHSNYVFCCNFNPQSNLIVS 146
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPP 168
G + IWD+KT + + +P + + + G ++ + + G C +W + SGQ
Sbjct: 147 GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-- 204
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVW 227
K I + KFSP+ ++ + D + K+W S L+ +++
Sbjct: 205 --CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 228 DAAFTLDS-RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
A F++ +++ +GS D+ +WN++ + ++ GH + + A
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA 308
Score = 60.1 bits (139), Expect = 8e-09
Identities = 46/220 (20%), Positives = 97/220 (44%), Gaps = 10/220 (4%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAVMLHPDQSQ 106
+K VS V F NG W+ + D +IW A + +K I + ++ V D +
Sbjct: 45 TKAVSSVKFSPNGEWLASSSADKLIKIW---GAYDGKFEKTISGHKLGISDVAWSSDSNL 101
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SG 165
++ + IWD+ + + + + + +P ++ + + + +W + +G
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 166 QPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRW 225
+ +P AHS F+ D +++V++S D +IW T+ L+ L D
Sbjct: 162 KCLKTLP-----AHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQ 265
V F+ + +++ + D+ +LW+ +G + Y GH+
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK 256
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 173 KKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFT 232
+K I+ H +S DS +LV+ S D + KIW S L+ L+ + +V+ F
Sbjct: 80 EKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSN-YVFCCNFN 138
Query: 233 LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
S + +GS D R+W+++ G + H ++A+ F
Sbjct: 139 PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179
Score = 48.8 bits (111), Expect = 2e-05
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 1/109 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P+ K + H+K KFSP+ L ++S D KIW D + + + +
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH-KLGIS 91
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
D A++ DS L + S D ++W++ G + GH + F Q
Sbjct: 92 DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQ 140
Score = 33.9 bits (74), Expect = 0.63
Identities = 32/151 (21%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Query: 18 SMVAAAGFQHI-RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD 76
S++ ++ + + R++D +S T +D + VS V F NG ++ D T ++WD
Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLK-TLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 242
Query: 77 PRAAPRTRCQKIF----QVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+ +C K + + + A I+ G + +++IW+L+T + Q +
Sbjct: 243 ---YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG 299
Query: 133 AEASIQDIAIDPAGKMM--AAVNNKGNCYVW 161
+ A P ++ AA+ N +W
Sbjct: 300 HTDVVISTACHPTENIIASAALENDKTIKLW 330
>AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens
cDNA FLJ20545 fis, clone KAT11476. ).
Length = 334
Score = 63.3 bits (147), Expect = 9e-10
Identities = 47/226 (20%), Positives = 101/226 (44%), Gaps = 11/226 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMV 109
+S V + + + + +D T +IWD + +C K + + V +P + I+
Sbjct: 90 ISDVAWSSDSNLLVSASDDKTLKIWDVSSG---KCLKTLKGHSNYVFCCNFNPQSNLIVS 146
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPP 168
G + IWD+KT + + +P + + + G ++ + + G C +W + SGQ
Sbjct: 147 GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-- 204
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVW 227
K I + KFSP+ ++ + D + K+W S L+ +++
Sbjct: 205 --CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 262
Query: 228 DAAFTLDS-RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
A F++ +++ +GS D+ +WN++ + ++ GH + + A
Sbjct: 263 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA 308
Score = 60.1 bits (139), Expect = 8e-09
Identities = 46/220 (20%), Positives = 97/220 (44%), Gaps = 10/220 (4%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAVMLHPDQSQ 106
+K VS V F NG W+ + D +IW A + +K I + ++ V D +
Sbjct: 45 TKAVSSVKFSPNGEWLASSSADKLIKIW---GAYDGKFEKTISGHKLGISDVAWSSDSNL 101
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SG 165
++ + IWD+ + + + + + +P ++ + + + +W + +G
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 161
Query: 166 QPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRW 225
+ +P AHS F+ D +++V++S D +IW T+ L+ L D
Sbjct: 162 KCLKTLP-----AHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQ 265
V F+ + +++ + D+ +LW+ +G + Y GH+
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK 256
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 173 KKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFT 232
+K I+ H +S DS +LV+ S D + KIW S L+ L+ + +V+ F
Sbjct: 80 EKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSN-YVFCCNFN 138
Query: 233 LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
S + +GS D R+W+++ G + H ++A+ F
Sbjct: 139 PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 179
Score = 48.8 bits (111), Expect = 2e-05
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 1/109 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P+ K + H+K KFSP+ L ++S D KIW D + + + +
Sbjct: 33 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH-KLGIS 91
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
D A++ DS L + S D ++W++ G + GH + F Q
Sbjct: 92 DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQ 140
Score = 33.9 bits (74), Expect = 0.63
Identities = 32/151 (21%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Query: 18 SMVAAAGFQHI-RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD 76
S++ ++ + + R++D +S T +D + VS V F NG ++ D T ++WD
Sbjct: 184 SLIVSSSYDGLCRIWDTASGQCLK-TLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 242
Query: 77 PRAAPRTRCQKIF----QVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+ +C K + + + A I+ G + +++IW+L+T + Q +
Sbjct: 243 ---YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG 299
Query: 133 AEASIQDIAIDPAGKMM--AAVNNKGNCYVW 161
+ A P ++ AA+ N +W
Sbjct: 300 HTDVVISTACHPTENIIASAALENDKTIKLW 330
>AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein
protein.
Length = 362
Score = 63.3 bits (147), Expect = 9e-10
Identities = 47/226 (20%), Positives = 101/226 (44%), Gaps = 11/226 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMV 109
+S V + + + + +D T +IWD + +C K + + V +P + I+
Sbjct: 118 ISDVAWSSDSNLLVSASDDKTLKIWDVSSG---KCLKTLKGHSNYVFCCNFNPQSNLIVS 174
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPP 168
G + IWD+KT + + +P + + + G ++ + + G C +W + SGQ
Sbjct: 175 GSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-- 232
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVW 227
K I + KFSP+ ++ + D + K+W S L+ +++
Sbjct: 233 --CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCI 290
Query: 228 DAAFTLDS-RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
A F++ +++ +GS D+ +WN++ + ++ GH + + A
Sbjct: 291 FANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTA 336
Score = 60.1 bits (139), Expect = 8e-09
Identities = 46/220 (20%), Positives = 97/220 (44%), Gaps = 10/220 (4%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAVMLHPDQSQ 106
+K VS V F NG W+ + D +IW A + +K I + ++ V D +
Sbjct: 73 TKAVSSVKFSPNGEWLASSSADKLIKIW---GAYDGKFEKTISGHKLGISDVAWSSDSNL 129
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SG 165
++ + IWD+ + + + + + +P ++ + + + +W + +G
Sbjct: 130 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTG 189
Query: 166 QPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRW 225
+ +P AHS F+ D +++V++S D +IW T+ L+ L D
Sbjct: 190 KCLKTLP-----AHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 244
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQ 265
V F+ + +++ + D+ +LW+ +G + Y GH+
Sbjct: 245 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHK 284
Score = 50.0 bits (114), Expect = 9e-06
Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
Query: 173 KKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFT 232
+K I+ H +S DS +LV+ S D + KIW S L+ L+ + +V+ F
Sbjct: 108 EKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSN-YVFCCNFN 166
Query: 233 LDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
S + +GS D R+W+++ G + H ++A+ F
Sbjct: 167 PQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHF 207
Score = 48.8 bits (111), Expect = 2e-05
Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 1/109 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P+ K + H+K KFSP+ L ++S D KIW D + + + +
Sbjct: 61 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH-KLGIS 119
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
D A++ DS L + S D ++W++ G + GH + F Q
Sbjct: 120 DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQ 168
Score = 33.9 bits (74), Expect = 0.63
Identities = 32/151 (21%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Query: 18 SMVAAAGFQHI-RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD 76
S++ ++ + + R++D +S T +D + VS V F NG ++ D T ++WD
Sbjct: 212 SLIVSSSYDGLCRIWDTASGQCLK-TLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWD 270
Query: 77 PRAAPRTRCQKIF----QVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+ +C K + + + A I+ G + +++IW+L+T + Q +
Sbjct: 271 ---YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG 327
Query: 133 AEASIQDIAIDPAGKMM--AAVNNKGNCYVW 161
+ A P ++ AA+ N +W
Sbjct: 328 HTDVVISTACHPTENIIASAALENDKTIKLW 358
>AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription
factor protein.
Length = 260
Score = 62.9 bits (146), Expect = 1e-09
Identities = 47/181 (25%), Positives = 77/181 (42%), Gaps = 7/181 (3%)
Query: 94 PVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVN 153
PV + D S ++ + I WDL + N L + D+ I P A+ +
Sbjct: 15 PVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGS 74
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDW 212
+ +WS P + H+ + C KF P+S L T S D + ++W
Sbjct: 75 HDRTARLWSFDRTYPLRIYAGHLAD-----VDCVKFHPNSNYLATGSTDKTVRLWSAQQG 129
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+R L + V AF+ + ++L + D +LW++ GTL +E GH IT+L
Sbjct: 130 NSVR-LFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLT 188
Query: 273 F 273
F
Sbjct: 189 F 189
Score = 60.1 bits (139), Expect = 8e-09
Identities = 35/144 (24%), Positives = 63/144 (43%), Gaps = 8/144 (5%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
+G D TAR+W + RT +I+ A V+ V HP+ + + G + +W +
Sbjct: 72 SGSHDRTARLW---SFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ 128
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ +L + +A P GK +A+ +W L+ + K + H+
Sbjct: 129 GNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLY----KELRGHTDNI 184
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIW 207
FSPDS ++ + S D S ++W
Sbjct: 185 TSLTFSPDSGLIASASMDNSVRVW 208
Score = 43.6 bits (98), Expect = 8e-04
Identities = 34/153 (22%), Positives = 64/153 (41%), Gaps = 4/153 (2%)
Query: 12 LEISPTSMVAAAGFQHIRLYDLSSANPD-PVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
L+ISP S+ A+G H R L S + P+ + +V V F N ++ TG D
Sbjct: 61 LDISPYSLYFASG-SHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDK 119
Query: 71 TARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI 130
T R+W + R + PV ++ P+ + + + +WDL + + +
Sbjct: 120 TVRLWSAQQGNSVRL--FTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKEL 177
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL 163
+I + P ++A+ + + VW +
Sbjct: 178 RGHTDNITSLTFSPDSGLIASASMDNSVRVWDI 210
Score = 41.5 bits (93), Expect = 0.003
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K + H +F DS+ L++ S D S + W + L + VWD +
Sbjct: 7 KILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFT-NTVLYQGHAYPVWDLDISP 65
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
S + +GS D ARLW+ +R R Y GH + + F
Sbjct: 66 YSLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKF 105
Score = 37.1 bits (82), Expect = 0.068
Identities = 26/116 (22%), Positives = 48/116 (41%), Gaps = 6/116 (5%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ ++ P S A G + +RL+ N V F V + F NG ++ +
Sbjct: 100 VDCVKFHPNSNYLATGSTDKTVRLWSAQQGNS--VRLFTGHRGPVLSLAFSPNGKYLASA 157
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLK 122
GED ++WD A T +++ + ++ PD I + +WD++
Sbjct: 158 GEDQRLKLWD--LASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR 211
>Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1
protein protein.
Length = 577
Score = 62.1 bits (144), Expect = 2e-09
Identities = 59/235 (25%), Positives = 94/235 (40%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + NGT + TG D ARIW + Q + P+ A+ + + I
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDG---NLASTLGQHKGPIFALKWNRKGNYI 344
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D A + C +V L
Sbjct: 345 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNTTFASCSTDMCIHVCRLGCD 402
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD----- 221
P K H+ K+ P +L + S D + KIW + +L+
Sbjct: 403 RP----VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY 458
Query: 222 TQRW--VWDAAFTLDSRFLFTGSS-DSYARLWNIERGTLEREYCGHQKAITALAF 273
T +W A +S + +S DS RLW+IERG HQ+ + ++AF
Sbjct: 459 TIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAF 513
Score = 57.2 bits (132), Expect = 6e-08
Identities = 51/217 (23%), Positives = 88/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ + G ++ + G D T IWD + Q F AP V + +
Sbjct: 337 WNRKGNYILSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNTTFASCSTDM-C 393
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D+ + + I DP+G ++A+ ++ +WS+ + V
Sbjct: 394 IHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQE----VCIHD 449
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AH+K K+SP + ML + S D + ++W L + Q V
Sbjct: 450 LQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKH-QEPV 508
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D +WN + G L Y G
Sbjct: 509 YSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 545
Score = 39.9 bits (89), Expect = 0.010
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 404 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 463
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 464 PTGPATSNPN-SNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 522
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 523 GSFDKCVHIWNTQSGNLVH 541
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + + L TGS D +AR+W E G L H+ I AL
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFARIWT-EDGNLASTLGQHKGPIFAL 335
>BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like
1X-linked protein.
Length = 577
Score = 62.1 bits (144), Expect = 2e-09
Identities = 59/235 (25%), Positives = 94/235 (40%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + NGT + TG D ARIW + Q + P+ A+ + + I
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDG---NLASTLGQHKGPIFALKWNRKGNYI 344
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D A + C +V L
Sbjct: 345 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNTTFASCSTDMCIHVCRLGCD 402
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD----- 221
P K H+ K+ P +L + S D + KIW + +L+
Sbjct: 403 RP----VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY 458
Query: 222 TQRW--VWDAAFTLDSRFLFTGSS-DSYARLWNIERGTLEREYCGHQKAITALAF 273
T +W A +S + +S DS RLW+IERG HQ+ + ++AF
Sbjct: 459 TIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAF 513
Score = 57.2 bits (132), Expect = 6e-08
Identities = 51/217 (23%), Positives = 88/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ + G ++ + G D T IWD + Q F AP V + +
Sbjct: 337 WNRKGNYILSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNTTFASCSTDM-C 393
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D+ + + I DP+G ++A+ ++ +WS+ + V
Sbjct: 394 IHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQE----VCIHD 449
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AH+K K+SP + ML + S D + ++W L + Q V
Sbjct: 450 LQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKH-QEPV 508
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D +WN + G L Y G
Sbjct: 509 YSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 545
Score = 39.9 bits (89), Expect = 0.010
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 404 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 463
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 464 PTGPATSNPN-SNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 522
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 523 GSFDKCVHIWNTQSGNLVH 541
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 228 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 287
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + + L TGS D +AR+W E G L H+ I AL
Sbjct: 288 NKDVTSLDWNTNGTLLATGSYDGFARIWT-EDGNLASTLGQHKGPIFAL 335
>BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein.
Length = 526
Score = 62.1 bits (144), Expect = 2e-09
Identities = 59/235 (25%), Positives = 94/235 (40%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + NGT + TG D ARIW + Q + P+ A+ + + I
Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDG---NLASTLGQHKGPIFALKWNRKGNYI 293
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D A + C +V L
Sbjct: 294 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNTTFASCSTDMCIHVCRLGCD 351
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD----- 221
P K H+ K+ P +L + S D + KIW + +L+
Sbjct: 352 RP----VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY 407
Query: 222 TQRW--VWDAAFTLDSRFLFTGSS-DSYARLWNIERGTLEREYCGHQKAITALAF 273
T +W A +S + +S DS RLW+IERG HQ+ + ++AF
Sbjct: 408 TIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAF 462
Score = 57.2 bits (132), Expect = 6e-08
Identities = 51/217 (23%), Positives = 88/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ + G ++ + G D T IWD + Q F AP V + +
Sbjct: 286 WNRKGNYILSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNTTFASCSTDM-C 342
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D+ + + I DP+G ++A+ ++ +WS+ + V
Sbjct: 343 IHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQE----VCIHD 398
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AH+K K+SP + ML + S D + ++W L + Q V
Sbjct: 399 LQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKH-QEPV 457
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D +WN + G L Y G
Sbjct: 458 YSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 494
Score = 39.9 bits (89), Expect = 0.010
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 353 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 412
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 413 PTGPATSNPN-SNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 471
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 472 GSFDKCVHIWNTQSGNLVH 490
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 177 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 236
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + + L TGS D +AR+W E G L H+ I AL
Sbjct: 237 NKDVTSLDWNTNGTLLATGSYDGFARIWT-EDGNLASTLGQHKGPIFAL 284
>BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat domain
containing 11 protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D + +IWD + C K+ + + L D+ I+ G + +WD+ T
Sbjct: 242 SGLRDNSIKIWDKTSL---ECLKVLTGHTG-SVLCLQYDERVIVTGSSDSTVRVWDVNTG 297
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + + +M + + VW ++ + ++ + H
Sbjct: 298 EVLNTLIHHNEAVLH---LRFSNGLMVTCSKDRSIAVWDMASATDITL-RRVLVGHRAAV 353
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
F D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 354 NVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 408
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 409 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 443
Score = 40.3 bits (90), Expect = 0.007
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
D +++ D S KIW + L+ L T + D R + TGSSDS R+W
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVL---CLQYDERVIVTGSSDSTVRVW 292
Query: 251 NIERGTLEREYCGHQKAITALAFKD 275
++ G + H +A+ L F +
Sbjct: 293 DVNTGEVLNTLIHHNEAVLHLRFSN 317
Score = 31.9 bits (69), Expect = 2.5
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 9 VNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
VN ++ +V+A+G + I+++ S+ + V T + ++ + ++ + +G
Sbjct: 353 VNVVDFDDKYIVSASGDRTIKVWSTSTC--EFVRTLNGHKRGIACLQYRDR--LVVSGSS 408
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T R+WD C ++ + + + D +I+ G G I +WDL+
Sbjct: 409 DNTIRLWDIECGA---CLRVLEGHEEL-VRCIRFDNKRIVSGAYDGKIKVWDLQA----A 460
Query: 129 LIPEAEAS 136
L P A AS
Sbjct: 461 LDPRAPAS 468
>AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 330
Score = 62.1 bits (144), Expect = 2e-09
Identities = 52/270 (19%), Positives = 120/270 (44%), Gaps = 11/270 (4%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
E V+S++ SP A+ + + + T + +S V + + + + +
Sbjct: 42 EAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSA 101
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
+D T ++WD R+ +C K + + V +P + I+ G + IW++KT +
Sbjct: 102 SDDKTLKLWDVRSG---KCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGK 158
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYAL 184
+ + + + + +G ++ + + G C +W + SGQ K + +
Sbjct: 159 CLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQ----CLKTLVDDDNPPVS 214
Query: 185 RCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDS-RFLFTGS 242
KFSP+ ++T + D + K+W S L+ + +++ A F++ +++ +GS
Sbjct: 215 FVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVSGS 274
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALA 272
D+ +WN++ + ++ GH + + A
Sbjct: 275 EDNLVYIWNLQTKEIVQKLQGHTDVVISAA 304
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 8/146 (5%)
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCK 187
L+ EA + + P G+ +A+ + +W + G+ +K + H+
Sbjct: 37 LVGHTEA-VSSVKFSPNGEWLASSSADRLIIIWGAYDGKY-----EKTLYGHNLEISDVA 90
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
+S DS+ LV+ S D + K+W L+ L+ + +V+ F S + +GS D
Sbjct: 91 WSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSN-YVFCCNFNPPSNLIISGSFDETV 149
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
++W ++ G + H ++A+ F
Sbjct: 150 KIWEVKTGKCLKTLSAHSDPVSAVHF 175
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 1/106 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P+ K + H++ KFSP+ L ++S D IW D + L +
Sbjct: 29 PNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLE-IS 87
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D A++ DS L + S D +LW++ G + GH + F
Sbjct: 88 DVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNF 133
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/151 (23%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Query: 18 SMVAAAGFQHI-RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD 76
S++ + + + R++D +S T +D + VS V F NG ++ T D T ++WD
Sbjct: 180 SLIVSGSYDGLCRIWDAASGQCLK-TLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWD 238
Query: 77 PRAAPRTRCQKIFQVQAP----VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
R RC K + Q + A I+ G + +++IW+L+T + Q +
Sbjct: 239 ---YSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG 295
Query: 133 AEASIQDIAIDPAGKMM--AAVNNKGNCYVW 161
+ A P ++ AA+ N +W
Sbjct: 296 HTDVVISAACHPTENLIASAALENDKTIKLW 326
>AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b
protein.
Length = 542
Score = 62.1 bits (144), Expect = 2e-09
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D + +IWD + C K+ + + L D+ I+ G + +WD+ T
Sbjct: 255 SGLRDNSIKIWDKTSL---ECLKVLTGHTG-SVLCLQYDERVIVTGSSDSTVRVWDVNTG 310
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + + +M + + VW ++ + ++ + H
Sbjct: 311 EVLNTLIHHNEAVLH---LRFSNGLMVTCSKDRSIAVWDMASATDITL-RRVLVGHRAAV 366
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
F D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 367 NVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 421
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 422 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 456
Score = 40.3 bits (90), Expect = 0.007
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
D +++ D S KIW + L+ L T + D R + TGSSDS R+W
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVL---CLQYDERVIVTGSSDSTVRVW 305
Query: 251 NIERGTLEREYCGHQKAITALAFKD 275
++ G + H +A+ L F +
Sbjct: 306 DVNTGEVLNTLIHHNEAVLHLRFSN 330
Score = 31.9 bits (69), Expect = 2.5
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 9 VNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
VN ++ +V+A+G + I+++ S+ + V T + ++ + ++ + +G
Sbjct: 366 VNVVDFDDKYIVSASGDRTIKVWSTSTC--EFVRTLNGHKRGIACLQYRDR--LVVSGSS 421
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T R+WD C ++ + + + D +I+ G G I +WDL+
Sbjct: 422 DNTIRLWDIECGA---CLRVLEGHEEL-VRCIRFDNKRIVSGAYDGKIKVWDLQA----A 473
Query: 129 LIPEAEAS 136
L P A AS
Sbjct: 474 LDPRAPAS 481
>AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X
variant protein.
Length = 540
Score = 62.1 bits (144), Expect = 2e-09
Identities = 59/235 (25%), Positives = 94/235 (40%), Gaps = 18/235 (7%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + NGT + TG D ARIW + Q + P+ A+ + + I
Sbjct: 251 NKDVTSLDWNTNGTLLATGSYDGFARIWTEDG---NLASTLGQHKGPIFALKWNRKGNYI 307
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNC-YVWSLSGQ 166
+ IWD T + +Q P A D+ D A + C +V L
Sbjct: 308 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDV--DWQNNTTFASCSTDMCIHVCRLGCD 365
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD----- 221
P K H+ K+ P +L + S D + KIW + +L+
Sbjct: 366 RP----VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIY 421
Query: 222 TQRW--VWDAAFTLDSRFLFTGSS-DSYARLWNIERGTLEREYCGHQKAITALAF 273
T +W A +S + +S DS RLW+IERG HQ+ + ++AF
Sbjct: 422 TIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAF 476
Score = 57.2 bits (132), Expect = 6e-08
Identities = 51/217 (23%), Positives = 88/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ + G ++ + G D T IWD + Q F AP V + +
Sbjct: 300 WNRKGNYILSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQNNTTFASCSTDM-C 356
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D+ + + I DP+G ++A+ ++ +WS+ + V
Sbjct: 357 IHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQE----VCIHD 412
Query: 176 ITAHSKYALRCKFSP---------DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AH+K K+SP + ML + S D + ++W L + Q V
Sbjct: 413 LQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKH-QEPV 471
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D ++L +GS D +WN + G L Y G
Sbjct: 472 YSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG 508
Score = 39.9 bits (89), Expect = 0.010
Identities = 28/139 (20%), Positives = 64/139 (46%), Gaps = 10/139 (7%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
PV TF+ + V+ + + +G + + +D T +IW + + ++I+ ++ +
Sbjct: 367 PVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWS 426
Query: 94 PVNAVMLHPDQSQIMVGDQS--GIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
P +P+ S IM+ S + +WD++ + + + + +A P GK +A+
Sbjct: 427 PTGPATSNPN-SNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLAS 485
Query: 152 VNNKGNCYVWSL-SGQPPH 169
+ ++W+ SG H
Sbjct: 486 GSFDKCVHIWNTQSGNLVH 504
Score = 37.9 bits (84), Expect = 0.039
Identities = 31/109 (28%), Positives = 47/109 (43%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-------SDWALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S +LR R+ +
Sbjct: 191 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPS 250
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + + L TGS D +AR+W E G L H+ I AL
Sbjct: 251 NKDVTSLDWNTNGTLLATGSYDGFARIWT-EDGNLASTLGQHKGPIFAL 298
>AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform C protein.
Length = 542
Score = 62.1 bits (144), Expect = 2e-09
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D + +IWD + C K+ + + L D+ I+ G + +WD+ T
Sbjct: 255 SGLRDNSIKIWDKTSL---ECLKVLTGHTG-SVLCLQYDERVIVTGSSDSTVRVWDVNTG 310
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + + +M + + VW ++ + ++ + H
Sbjct: 311 EVLNTLIHHNEAVLH---LRFSNGLMVTCSKDRSIAVWDMASATDITL-RRVLVGHRAAV 366
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
F D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 367 NVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 421
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 422 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 456
Score = 40.3 bits (90), Expect = 0.007
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
D +++ D S KIW + L+ L T + D R + TGSSDS R+W
Sbjct: 249 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVL---CLQYDERVIVTGSSDSTVRVW 305
Query: 251 NIERGTLEREYCGHQKAITALAFKD 275
++ G + H +A+ L F +
Sbjct: 306 DVNTGEVLNTLIHHNEAVLHLRFSN 330
Score = 31.9 bits (69), Expect = 2.5
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 9 VNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
VN ++ +V+A+G + I+++ S+ + V T + ++ + ++ + +G
Sbjct: 366 VNVVDFDDKYIVSASGDRTIKVWSTSTC--EFVRTLNGHKRGIACLQYRDR--LVVSGSS 421
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T R+WD C ++ + + + D +I+ G G I +WDL+
Sbjct: 422 DNTIRLWDIECGA---CLRVLEGHEEL-VRCIRFDNKRIVSGAYDGKIKVWDLQA----A 473
Query: 129 LIPEAEAS 136
L P A AS
Sbjct: 474 LDPRAPAS 481
>AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform B protein.
Length = 529
Score = 62.1 bits (144), Expect = 2e-09
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D + +IWD + C K+ + + L D+ I+ G + +WD+ T
Sbjct: 242 SGLRDNSIKIWDKTSL---ECLKVLTGHTG-SVLCLQYDERVIVTGSSDSTVRVWDVNTG 297
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + + +M + + VW ++ + ++ + H
Sbjct: 298 EVLNTLIHHNEAVLH---LRFSNGLMVTCSKDRSIAVWDMASATDITL-RRVLVGHRAAV 353
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
F D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 354 NVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 408
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 409 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 443
Score = 40.3 bits (90), Expect = 0.007
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
D +++ D S KIW + L+ L T + D R + TGSSDS R+W
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVL---CLQYDERVIVTGSSDSTVRVW 292
Query: 251 NIERGTLEREYCGHQKAITALAFKD 275
++ G + H +A+ L F +
Sbjct: 293 DVNTGEVLNTLIHHNEAVLHLRFSN 317
Score = 31.9 bits (69), Expect = 2.5
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 9 VNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
VN ++ +V+A+G + I+++ S+ + V T + ++ + ++ + +G
Sbjct: 353 VNVVDFDDKYIVSASGDRTIKVWSTSTC--EFVRTLNGHKRGIACLQYRDR--LVVSGSS 408
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T R+WD C ++ + + + D +I+ G G I +WDL+
Sbjct: 409 DNTIRLWDIECGA---CLRVLEGHEEL-VRCIRFDNKRIVSGAYDGKIKVWDLQA----A 460
Query: 129 LIPEAEAS 136
L P A AS
Sbjct: 461 LDPRAPAS 468
>AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats
protein beta-TRCP2 isoform A protein.
Length = 508
Score = 62.1 bits (144), Expect = 2e-09
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D + +IWD + C K+ + + L D+ I+ G + +WD+ T
Sbjct: 221 SGLRDNSIKIWDKTSL---ECLKVLTGHTG-SVLCLQYDERVIVTGSSDSTVRVWDVNTG 276
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + + +M + + VW ++ + ++ + H
Sbjct: 277 EVLNTLIHHNEAVLH---LRFSNGLMVTCSKDRSIAVWDMASATDITL-RRVLVGHRAAV 332
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
F D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 333 NVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 387
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 388 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 422
Score = 40.3 bits (90), Expect = 0.007
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
D +++ D S KIW + L+ L T + D R + TGSSDS R+W
Sbjct: 215 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVL---CLQYDERVIVTGSSDSTVRVW 271
Query: 251 NIERGTLEREYCGHQKAITALAFKD 275
++ G + H +A+ L F +
Sbjct: 272 DVNTGEVLNTLIHHNEAVLHLRFSN 296
Score = 31.9 bits (69), Expect = 2.5
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 9 VNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
VN ++ +V+A+G + I+++ S+ + V T + ++ + ++ + +G
Sbjct: 332 VNVVDFDDKYIVSASGDRTIKVWSTSTC--EFVRTLNGHKRGIACLQYRDR--LVVSGSS 387
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T R+WD C ++ + + + D +I+ G G I +WDL+
Sbjct: 388 DNTIRLWDIECGA---CLRVLEGHEEL-VRCIRFDNKRIVSGAYDGKIKVWDLQA----A 439
Query: 129 LIPEAEAS 136
L P A AS
Sbjct: 440 LDPRAPAS 447
>AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein.
Length = 550
Score = 62.1 bits (144), Expect = 2e-09
Identities = 51/215 (23%), Positives = 94/215 (43%), Gaps = 14/215 (6%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D + +IWD + C K+ + + L D+ I+ G + +WD+ T
Sbjct: 263 SGLRDNSIKIWDKTSL---ECLKVLTGHTG-SVLCLQYDERVIVTGSSDSTVRVWDVNTG 318
Query: 125 QN-EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
+ LI EA + + + +M + + VW ++ + ++ + H
Sbjct: 319 EVLNTLIHHNEAVLH---LRFSNGLMVTCSKDRSIAVWDMASATDITL-RRVLVGHRAAV 374
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
F D +V+ SGD + K+W TS +R L +R + A R + +GSS
Sbjct: 375 NVVDF--DDKYIVSASGDRTIKVWSTSTCEFVRTLNGH-KRGI--ACLQYRDRLVVSGSS 429
Query: 244 DSYARLWNIERGTLEREYCGHQKAITALAFKDQPV 278
D+ RLW+IE G R GH++ + + F ++ +
Sbjct: 430 DNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRI 464
Score = 40.3 bits (90), Expect = 0.007
Identities = 24/85 (28%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
D +++ D S KIW + L+ L T + D R + TGSSDS R+W
Sbjct: 257 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVL---CLQYDERVIVTGSSDSTVRVW 313
Query: 251 NIERGTLEREYCGHQKAITALAFKD 275
++ G + H +A+ L F +
Sbjct: 314 DVNTGEVLNTLIHHNEAVLHLRFSN 338
Score = 31.9 bits (69), Expect = 2.5
Identities = 29/128 (22%), Positives = 58/128 (45%), Gaps = 12/128 (9%)
Query: 9 VNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
VN ++ +V+A+G + I+++ S+ + V T + ++ + ++ + +G
Sbjct: 374 VNVVDFDDKYIVSASGDRTIKVWSTSTC--EFVRTLNGHKRGIACLQYRDR--LVVSGSS 429
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T R+WD C ++ + + + D +I+ G G I +WDL+
Sbjct: 430 DNTIRLWDIECGA---CLRVLEGHEEL-VRCIRFDNKRIVSGAYDGKIKVWDLQA----A 481
Query: 129 LIPEAEAS 136
L P A AS
Sbjct: 482 LDPRAPAS 489
>X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein.
Length = 799
Score = 61.7 bits (143), Expect = 3e-09
Identities = 44/206 (21%), Positives = 82/206 (39%), Gaps = 7/206 (3%)
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D RI D + A + ++ PV PD++ ++ + G + +W L+T
Sbjct: 521 DDVLERIMDEKTASELKI--LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCL 578
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ D P G + + +W+ H P + H +
Sbjct: 579 VGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD----HYQPLRIFAGHLADVNCTR 634
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
F P+S + T S D + ++W + +R + + + F+ + RFL TG++D
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPNGRFLATGATDGRV 693
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
LW+I G + E GH + +L F
Sbjct: 694 LLWDIGHGLMVGELKGHTDTVCSLRF 719
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSG 114
F G + +GG D AR+W A + +IF A VN HP+ + + G
Sbjct: 593 FSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
+ +WD+ ++ + I + P G+ +A G +W + H +
Sbjct: 650 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG----HGLMVG 705
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H+ +FS D +L + S D + ++W
Sbjct: 706 ELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 46.0 bits (104), Expect = 1e-04
Identities = 49/231 (21%), Positives = 91/231 (39%), Gaps = 18/231 (7%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF ++ + ++ V + + + G D T R+W P+ K+ V+ + ++
Sbjct: 465 TFLNVYQGLTAVDVTDDSSLIAGGFADSTVRVWS--VTPK----KLRSVKQASDLSLIDK 518
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ ++ I D KT +++ + + P + + + G +WS
Sbjct: 519 ESDDVLE-------RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L K H+ +FSP V+ D A++W T + LR
Sbjct: 572 LQTFTCLVGYK----GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHL 627
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V F +S ++ TGS+D RLW++ G R + GH+ I +L F
Sbjct: 628 AD-VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTF 677
Score = 38.3 bits (85), Expect = 0.029
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ-VQAPVNAV 98
P+ F +V+ F N ++ TG D T R+WD C +IF + P++++
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD---VLNGNCVRIFTGHKGPIHSL 675
Query: 99 MLHPDQSQIMVGDQSGIIHIWDL 121
P+ + G G + +WD+
Sbjct: 676 TFSPNGRFLATGATDGRVLLWDI 698
Score = 37.5 bits (83), Expect = 0.051
Identities = 41/197 (20%), Positives = 68/197 (34%), Gaps = 9/197 (4%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
F + ++ + ED T R+W + K PV P + G +
Sbjct: 551 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY--PVWDTQFSPYGYYFVSGGHDRV 608
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKK 174
+W Q ++ A + P +A + +W L+G +
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCV-----R 663
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
T H FSP+ L T + D +W ++ EL+ T V F+ D
Sbjct: 664 IFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDT-VCSLRFSRD 722
Query: 235 SRFLFTGSSDSYARLWN 251
L +GS D+ RLW+
Sbjct: 723 GEILASGSMDNTVRLWD 739
>U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100
protein.
Length = 800
Score = 61.7 bits (143), Expect = 3e-09
Identities = 44/206 (21%), Positives = 82/206 (39%), Gaps = 7/206 (3%)
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D RI D + A + ++ PV PD++ ++ + G + +W L+T
Sbjct: 521 DDVLERIMDEKTASELKI--LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCL 578
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ D P G + + +W+ H P + H +
Sbjct: 579 VGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD----HYQPLRIFAGHLADVNCTR 634
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
F P+S + T S D + ++W + +R + + + F+ + RFL TG++D
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPNGRFLATGATDGRV 693
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
LW+I G + E GH + +L F
Sbjct: 694 LLWDIGHGLMVGELKGHTDTVCSLRF 719
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSG 114
F G + +GG D AR+W A + +IF A VN HP+ + + G
Sbjct: 593 FSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
+ +WD+ ++ + I + P G+ +A G +W + H +
Sbjct: 650 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG----HGLMVG 705
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H+ +FS D +L + S D + ++W
Sbjct: 706 ELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 44.4 bits (100), Expect = 4e-04
Identities = 49/231 (21%), Positives = 90/231 (38%), Gaps = 18/231 (7%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + ++ V + + + G D T R+W P+ K+ V+ + ++
Sbjct: 465 TFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWS--VTPK----KLRSVKQASDLSLIDK 518
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ ++ I D KT +++ + + P + + + G +WS
Sbjct: 519 ESDDVLE-------RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L K H+ +FSP V+ D A++W T + LR
Sbjct: 572 LQTFTCLVGYK----GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHL 627
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V F +S ++ TGS+D RLW++ G R + GH+ I +L F
Sbjct: 628 AD-VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTF 677
Score = 38.3 bits (85), Expect = 0.029
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ-VQAPVNAV 98
P+ F +V+ F N ++ TG D T R+WD C +IF + P++++
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD---VLNGNCVRIFTGHKGPIHSL 675
Query: 99 MLHPDQSQIMVGDQSGIIHIWDL 121
P+ + G G + +WD+
Sbjct: 676 TFSPNGRFLATGATDGRVLLWDI 698
Score = 37.5 bits (83), Expect = 0.051
Identities = 41/197 (20%), Positives = 68/197 (34%), Gaps = 9/197 (4%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
F + ++ + ED T R+W + K PV P + G +
Sbjct: 551 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY--PVWDTQFSPYGYYFVSGGHDRV 608
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKK 174
+W Q ++ A + P +A + +W L+G +
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCV-----R 663
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
T H FSP+ L T + D +W ++ EL+ T V F+ D
Sbjct: 664 IFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDT-VCSLRFSRD 722
Query: 235 SRFLFTGSSDSYARLWN 251
L +GS D+ RLW+
Sbjct: 723 GEILASGSMDNTVRLWD 739
>U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor
protein.
Length = 801
Score = 61.7 bits (143), Expect = 3e-09
Identities = 44/206 (21%), Positives = 82/206 (39%), Gaps = 7/206 (3%)
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D RI D + A + ++ PV PD++ ++ + G + +W L+T
Sbjct: 522 DDVLERIMDEKTASELKI--LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCL 579
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ D P G + + +W+ H P + H +
Sbjct: 580 VGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD----HYQPLRIFAGHLADVNCTR 635
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
F P+S + T S D + ++W + +R + + + F+ + RFL TG++D
Sbjct: 636 FHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPNGRFLATGATDGRV 694
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
LW+I G + E GH + +L F
Sbjct: 695 LLWDIGHGLMVGELKGHTDTVCSLRF 720
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSG 114
F G + +GG D AR+W A + +IF A VN HP+ + + G
Sbjct: 594 FSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 650
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
+ +WD+ ++ + I + P G+ +A G +W + H +
Sbjct: 651 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG----HGLMVG 706
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H+ +FS D +L + S D + ++W
Sbjct: 707 ELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 739
Score = 44.4 bits (100), Expect = 4e-04
Identities = 49/231 (21%), Positives = 90/231 (38%), Gaps = 18/231 (7%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + ++ V + + + G D T R+W P+ K+ V+ + ++
Sbjct: 466 TFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWS--VTPK----KLRSVKQASDLSLIDK 519
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ ++ I D KT +++ + + P + + + G +WS
Sbjct: 520 ESDDVLE-------RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 572
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L K H+ +FSP V+ D A++W T + LR
Sbjct: 573 LQTFTCLVGYK----GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHL 628
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V F +S ++ TGS+D RLW++ G R + GH+ I +L F
Sbjct: 629 AD-VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTF 678
Score = 38.3 bits (85), Expect = 0.029
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ-VQAPVNAV 98
P+ F +V+ F N ++ TG D T R+WD C +IF + P++++
Sbjct: 620 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD---VLNGNCVRIFTGHKGPIHSL 676
Query: 99 MLHPDQSQIMVGDQSGIIHIWDL 121
P+ + G G + +WD+
Sbjct: 677 TFSPNGRFLATGATDGRVLLWDI 699
Score = 37.5 bits (83), Expect = 0.051
Identities = 41/197 (20%), Positives = 68/197 (34%), Gaps = 9/197 (4%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
F + ++ + ED T R+W + K PV P + G +
Sbjct: 552 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY--PVWDTQFSPYGYYFVSGGHDRV 609
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKK 174
+W Q ++ A + P +A + +W L+G +
Sbjct: 610 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCV-----R 664
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
T H FSP+ L T + D +W ++ EL+ T V F+ D
Sbjct: 665 IFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDT-VCSLRFSRD 723
Query: 235 SRFLFTGSSDSYARLWN 251
L +GS D+ RLW+
Sbjct: 724 GEILASGSMDNTVRLWD 740
>CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein.
Length = 330
Score = 61.7 bits (143), Expect = 3e-09
Identities = 52/270 (19%), Positives = 119/270 (44%), Gaps = 11/270 (4%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
E V+S++ SP A+ + + + T + +S V + + + + +
Sbjct: 42 EAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSA 101
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
+D T ++WD R+ +C K + + V +P + I+ G + IW++KT +
Sbjct: 102 SDDKTLKLWDVRSG---KCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGK 158
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYAL 184
+ + + + + +G ++ + + G C +W + SGQ K + +
Sbjct: 159 CLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQ----CLKTLVDDDNPPVS 214
Query: 185 RCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDS-RFLFTGS 242
KFSP+ ++T + D + K+W S L+ +++ A F++ +++ +GS
Sbjct: 215 FVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 274
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALA 272
D+ +WN++ + ++ GH + + A
Sbjct: 275 EDNLVYIWNLQTKEIVQKLQGHTDVVISAA 304
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 8/146 (5%)
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCK 187
L+ EA + + P G+ +A+ + +W + G+ +K + H+
Sbjct: 37 LVGHTEA-VSSVKFSPNGEWLASSSADRLIIIWGAYDGKY-----EKTLYGHNLEISDVA 90
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
+S DS+ LV+ S D + K+W L+ L+ + +V+ F S + +GS D
Sbjct: 91 WSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSN-YVFCCNFNPPSNLIISGSFDETV 149
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
++W ++ G + H ++A+ F
Sbjct: 150 KIWEVKTGKCLKTLSAHSDPVSAVHF 175
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 1/106 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P+ K + H++ KFSP+ L ++S D IW D + L +
Sbjct: 29 PNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLE-IS 87
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D A++ DS L + S D +LW++ G + GH + F
Sbjct: 88 DVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNF 133
Score = 37.9 bits (84), Expect = 0.039
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Query: 18 SMVAAAGFQHI-RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD 76
S++ + + + R++D +S T +D + VS V F NG ++ T D T ++WD
Sbjct: 180 SLIVSGSYDGLCRIWDAASGQCLK-TLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWD 238
Query: 77 PRAAPRTRCQKIF----QVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
R RC K + + + A I+ G + +++IW+L+T + Q +
Sbjct: 239 ---YSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG 295
Query: 133 AEASIQDIAIDPAGKMM--AAVNNKGNCYVW 161
+ A P ++ AA+ N +W
Sbjct: 296 HTDVVISAACHPTENLIASAALENDKTIKLW 326
>BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 61.7 bits (143), Expect = 3e-09
Identities = 44/206 (21%), Positives = 82/206 (39%), Gaps = 7/206 (3%)
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D RI D + A + ++ PV PD++ ++ + G + +W L+T
Sbjct: 521 DDVLERIMDEKTASELKI--LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCL 578
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ D P G + + +W+ H P + H +
Sbjct: 579 VGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD----HYQPLRIFAGHLADVNCTR 634
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
F P+S + T S D + ++W + +R + + + F+ + RFL TG++D
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPNGRFLATGATDGRV 693
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
LW+I G + E GH + +L F
Sbjct: 694 LLWDIGHGLMVGELKGHTDTVCSLRF 719
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSG 114
F G + +GG D AR+W A + +IF A VN HP+ + + G
Sbjct: 593 FSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
+ +WD+ ++ + I + P G+ +A G +W + H +
Sbjct: 650 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG----HGLMVG 705
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H+ +FS D +L + S D + ++W
Sbjct: 706 ELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 44.4 bits (100), Expect = 4e-04
Identities = 49/231 (21%), Positives = 90/231 (38%), Gaps = 18/231 (7%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + ++ V + + + G D T R+W P+ K+ V+ + ++
Sbjct: 465 TFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWS--VTPK----KLRSVKQASDLSLIDK 518
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ ++ I D KT +++ + + P + + + G +WS
Sbjct: 519 ESDDVLE-------RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L K H+ +FSP V+ D A++W T + LR
Sbjct: 572 LQTFTCLVGYK----GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHL 627
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V F +S ++ TGS+D RLW++ G R + GH+ I +L F
Sbjct: 628 AD-VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTF 677
Score = 38.3 bits (85), Expect = 0.029
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ-VQAPVNAV 98
P+ F +V+ F N ++ TG D T R+WD C +IF + P++++
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD---VLNGNCVRIFTGHKGPIHSL 675
Query: 99 MLHPDQSQIMVGDQSGIIHIWDL 121
P+ + G G + +WD+
Sbjct: 676 TFSPNGRFLATGATDGRVLLWDI 698
Score = 37.5 bits (83), Expect = 0.051
Identities = 41/197 (20%), Positives = 68/197 (34%), Gaps = 9/197 (4%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
F + ++ + ED T R+W + K PV P + G +
Sbjct: 551 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY--PVWDTQFSPYGYYFVSGGHDRV 608
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKK 174
+W Q ++ A + P +A + +W L+G +
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCV-----R 663
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
T H FSP+ L T + D +W ++ EL+ T V F+ D
Sbjct: 664 IFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDT-VCSLRFSRD 722
Query: 235 SRFLFTGSSDSYARLWN 251
L +GS D+ RLW+
Sbjct: 723 GEILASGSMDNTVRLWD 739
>BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B
protein.
Length = 330
Score = 61.7 bits (143), Expect = 3e-09
Identities = 52/270 (19%), Positives = 119/270 (44%), Gaps = 11/270 (4%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
E V+S++ SP A+ + + + T + +S V + + + + +
Sbjct: 42 EAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSA 101
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
+D T ++WD R+ +C K + + V +P + I+ G + IW++KT +
Sbjct: 102 SDDKTLKLWDVRSG---KCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGK 158
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYAL 184
+ + + + + +G ++ + + G C +W + SGQ K + +
Sbjct: 159 CLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQ----CLKTLVDDDNPPVS 214
Query: 185 RCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDS-RFLFTGS 242
KFSP+ ++T + D + K+W S L+ +++ A F++ +++ +GS
Sbjct: 215 FVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGS 274
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALA 272
D+ +WN++ + ++ GH + + A
Sbjct: 275 EDNLVYIWNLQTKEIVQKLQGHTDVVISAA 304
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/146 (21%), Positives = 65/146 (44%), Gaps = 8/146 (5%)
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCK 187
L+ EA + + P G+ +A+ + +W + G+ +K + H+
Sbjct: 37 LVGHTEA-VSSVKFSPNGEWLASSSADRLIIIWGAYDGKY-----EKTLYGHNLEISDVA 90
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
+S DS+ LV+ S D + K+W L+ L+ + +V+ F S + +GS D
Sbjct: 91 WSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSN-YVFCCNFNPPSNLIISGSFDETV 149
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
++W ++ G + H ++A+ F
Sbjct: 150 KIWEVKTGKCLKTLSAHSDPVSAVHF 175
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 1/106 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P+ K + H++ KFSP+ L ++S D IW D + L +
Sbjct: 29 PNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLE-IS 87
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D A++ DS L + S D +LW++ G + GH + F
Sbjct: 88 DVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNF 133
Score = 37.9 bits (84), Expect = 0.039
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 11/151 (7%)
Query: 18 SMVAAAGFQHI-RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD 76
S++ + + + R++D +S T +D + VS V F NG ++ T D T ++WD
Sbjct: 180 SLIVSGSYDGLCRIWDAASGQCLK-TLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWD 238
Query: 77 PRAAPRTRCQKIF----QVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
R RC K + + + A I+ G + +++IW+L+T + Q +
Sbjct: 239 ---YSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQG 295
Query: 133 AEASIQDIAIDPAGKMM--AAVNNKGNCYVW 161
+ A P ++ AA+ N +W
Sbjct: 296 HTDVVISAACHPTENLIASAALENDKTIKLW 326
>AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 61.7 bits (143), Expect = 3e-09
Identities = 44/206 (21%), Positives = 82/206 (39%), Gaps = 7/206 (3%)
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D RI D + A + ++ PV PD++ ++ + G + +W L+T
Sbjct: 521 DDVLERIMDEKTASELKI--LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCL 578
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ D P G + + +W+ H P + H +
Sbjct: 579 VGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD----HYQPLRIFAGHLADVNCTR 634
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
F P+S + T S D + ++W + +R + + + F+ + RFL TG++D
Sbjct: 635 FHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPNGRFLATGATDGRV 693
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
LW+I G + E GH + +L F
Sbjct: 694 LLWDIGHGLMVGELKGHTDTVCSLRF 719
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSG 114
F G + +GG D AR+W A + +IF A VN HP+ + + G
Sbjct: 593 FSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
+ +WD+ ++ + I + P G+ +A G +W + H +
Sbjct: 650 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG----HGLMVG 705
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H+ +FS D +L + S D + ++W
Sbjct: 706 ELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 44.4 bits (100), Expect = 4e-04
Identities = 49/231 (21%), Positives = 90/231 (38%), Gaps = 18/231 (7%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + ++ V + + + G D T R+W P+ K+ V+ + ++
Sbjct: 465 TFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWS--VTPK----KLRSVKQASDLSLIDK 518
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ ++ I D KT +++ + + P + + + G +WS
Sbjct: 519 ESDDVLE-------RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 571
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L K H+ +FSP V+ D A++W T + LR
Sbjct: 572 LQTFTCLVGYK----GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHL 627
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V F +S ++ TGS+D RLW++ G R + GH+ I +L F
Sbjct: 628 AD-VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTF 677
Score = 38.3 bits (85), Expect = 0.029
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ-VQAPVNAV 98
P+ F +V+ F N ++ TG D T R+WD C +IF + P++++
Sbjct: 619 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD---VLNGNCVRIFTGHKGPIHSL 675
Query: 99 MLHPDQSQIMVGDQSGIIHIWDL 121
P+ + G G + +WD+
Sbjct: 676 TFSPNGRFLATGATDGRVLLWDI 698
Score = 37.5 bits (83), Expect = 0.051
Identities = 41/197 (20%), Positives = 68/197 (34%), Gaps = 9/197 (4%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
F + ++ + ED T R+W + K PV P + G +
Sbjct: 551 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY--PVWDTQFSPYGYYFVSGGHDRV 608
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKK 174
+W Q ++ A + P +A + +W L+G +
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCV-----R 663
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
T H FSP+ L T + D +W ++ EL+ T V F+ D
Sbjct: 664 IFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDT-VCSLRFSRD 722
Query: 235 SRFLFTGSSDSYARLWN 251
L +GS D+ RLW+
Sbjct: 723 GEILASGSMDNTVRLWD 739
>AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiation
factor TFIID subunit 5 variant protein.
Length = 803
Score = 61.7 bits (143), Expect = 3e-09
Identities = 44/206 (21%), Positives = 82/206 (39%), Gaps = 7/206 (3%)
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D RI D + A + ++ PV PD++ ++ + G + +W L+T
Sbjct: 524 DDVLERIMDEKTASELKI--LYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCL 581
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ D P G + + +W+ H P + H +
Sbjct: 582 VGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATD----HYQPLRIFAGHLADVNCTR 637
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
F P+S + T S D + ++W + +R + + + F+ + RFL TG++D
Sbjct: 638 FHPNSNYVATGSADRTVRLWDVLNGNCVR-IFTGHKGPIHSLTFSPNGRFLATGATDGRV 696
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
LW+I G + E GH + +L F
Sbjct: 697 LLWDIGHGLMVGELKGHTDTVCSLRF 722
Score = 58.0 bits (134), Expect = 3e-08
Identities = 34/153 (22%), Positives = 62/153 (40%), Gaps = 8/153 (5%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSG 114
F G + +GG D AR+W A + +IF A VN HP+ + + G
Sbjct: 596 FSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADR 652
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
+ +WD+ ++ + I + P G+ +A G +W + H +
Sbjct: 653 TVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG----HGLMVG 708
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H+ +FS D +L + S D + ++W
Sbjct: 709 ELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 741
Score = 44.4 bits (100), Expect = 4e-04
Identities = 49/231 (21%), Positives = 90/231 (38%), Gaps = 18/231 (7%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + ++ V + + + G D T R+W P+ K+ V+ + ++
Sbjct: 468 TFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWS--VTPK----KLRSVKQASDLSLIDK 521
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+ ++ I D KT +++ + + P + + + G +WS
Sbjct: 522 ESDDVLE-------RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWS 574
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L K H+ +FSP V+ D A++W T + LR
Sbjct: 575 LQTFTCLVGYK----GHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHL 630
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V F +S ++ TGS+D RLW++ G R + GH+ I +L F
Sbjct: 631 AD-VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTF 680
Score = 38.3 bits (85), Expect = 0.029
Identities = 21/83 (25%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ-VQAPVNAV 98
P+ F +V+ F N ++ TG D T R+WD C +IF + P++++
Sbjct: 622 PLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWD---VLNGNCVRIFTGHKGPIHSL 678
Query: 99 MLHPDQSQIMVGDQSGIIHIWDL 121
P+ + G G + +WD+
Sbjct: 679 TFSPNGRFLATGATDGRVLLWDI 701
Score = 37.5 bits (83), Expect = 0.051
Identities = 41/197 (20%), Positives = 68/197 (34%), Gaps = 9/197 (4%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
F + ++ + ED T R+W + K PV P + G +
Sbjct: 554 FSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY--PVWDTQFSPYGYYFVSGGHDRV 611
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKK 174
+W Q ++ A + P +A + +W L+G +
Sbjct: 612 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCV-----R 666
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
T H FSP+ L T + D +W ++ EL+ T V F+ D
Sbjct: 667 IFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDT-VCSLRFSRD 725
Query: 235 SRFLFTGSSDSYARLWN 251
L +GS D+ RLW+
Sbjct: 726 GEILASGSMDNTVRLWD 742
>BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1
(Drosophila) protein.
Length = 485
Score = 61.3 bits (142), Expect = 4e-09
Identities = 54/244 (22%), Positives = 102/244 (41%), Gaps = 9/244 (3%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+R++D ++ + + T S R G +Y+ +D T ++W RA C+
Sbjct: 228 VRIWDTTAGRCERILTGHTQSVTCLRWG---GDGLLYSASQDRTIKVW--RAHDGVLCRT 282
Query: 88 IFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK 147
+ VN + L D + + + + Q + E S ++ +
Sbjct: 283 LQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPE 342
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + ++ ++WS + P +T H + FSPDS ++ + S D S K+W
Sbjct: 343 RLVSGSDDFTLFLWSPAEDKK---PLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 399
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKA 267
L LR V+ A++ DSR L +GSSDS ++W+++ L + GH
Sbjct: 400 DGRTGKYLASLRGHVAA-VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADE 458
Query: 268 ITAL 271
+ A+
Sbjct: 459 VYAV 462
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 9/141 (6%)
Query: 136 SIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
++ +A P GK +A+ + W LS + PH K H + L +SPD L
Sbjct: 116 AVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCK----GHRHWVLSISWSPDGKKL 171
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWV----WDAAFTL-DSRFLFTGSSDSYARLW 250
+ + +W S + +W+ W+ + R++ + S D R+W
Sbjct: 172 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 231
Query: 251 NIERGTLEREYCGHQKAITAL 271
+ G ER GH +++T L
Sbjct: 232 DTTAGRCERILTGHTQSVTCL 252
Score = 46.4 bits (105), Expect = 1e-04
Identities = 58/250 (23%), Positives = 96/250 (38%), Gaps = 17/250 (6%)
Query: 33 LSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPR----TRCQKI 88
L+ +P P+ F ++ VS +G + T E I+ P+A R TRC
Sbjct: 52 LAQEDPLPLAFFVHDAEIVSSLGKTLESQAVET--EKVLDIIYQPQAIFRVRAVTRCTSS 109
Query: 89 FQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK 147
+ + V +V P + G + WDL T+ + I+ P GK
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 169
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKF-----SPDSTMLVTTSGDC 202
+A+ G +W S + + HSK+ + +P+ + ++S D
Sbjct: 170 KLASGCKNGQILLWDPSTGKQ---VGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDG 226
Query: 203 SAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYC 262
S +IW T+ R L TQ V + D L++ S D ++W G L R
Sbjct: 227 SVRIWDTTAGRCERILTGHTQS-VTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQ 284
Query: 263 GHQKAITALA 272
GH + +A
Sbjct: 285 GHGHWVNTMA 294
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ HS+ + FSP L + SGD + + W S + + WV +++ D
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLST-ETPHFTCKGHRHWVLSISWSPDG 168
Query: 236 RFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAFK 274
+ L +G + LW+ G + R GH K IT L+++
Sbjct: 169 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWE 208
>BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein.
Length = 484
Score = 61.3 bits (142), Expect = 4e-09
Identities = 54/244 (22%), Positives = 102/244 (41%), Gaps = 9/244 (3%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+R++D ++ + + T S R G +Y+ +D T ++W RA C+
Sbjct: 227 VRIWDTTAGRCERILTGHTQSVTCLRWG---GDGLLYSASQDRTIKVW--RAHDGVLCRT 281
Query: 88 IFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK 147
+ VN + L D + + + + Q + E S ++ +
Sbjct: 282 LQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPE 341
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + ++ ++WS + P +T H + FSPDS ++ + S D S K+W
Sbjct: 342 RLVSGSDDFTLFLWSPAEDKK---PLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 398
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKA 267
L LR V+ A++ DSR L +GSSDS ++W+++ L + GH
Sbjct: 399 DGRTGKYLASLRGHVAA-VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADE 457
Query: 268 ITAL 271
+ A+
Sbjct: 458 VYAV 461
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 9/141 (6%)
Query: 136 SIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
++ +A P GK +A+ + W LS + PH K H + L +SPD L
Sbjct: 115 AVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCK----GHRHWVLSISWSPDGKKL 170
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWV----WDAAFTL-DSRFLFTGSSDSYARLW 250
+ + +W S + +W+ W+ + R++ + S D R+W
Sbjct: 171 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 230
Query: 251 NIERGTLEREYCGHQKAITAL 271
+ G ER GH +++T L
Sbjct: 231 DTTAGRCERILTGHTQSVTCL 251
Score = 46.4 bits (105), Expect = 1e-04
Identities = 58/250 (23%), Positives = 96/250 (38%), Gaps = 17/250 (6%)
Query: 33 LSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPR----TRCQKI 88
L+ +P P+ F ++ VS +G + T E I+ P+A R TRC
Sbjct: 51 LAQEDPLPLAFFVHDAEIVSSLGKTLESQAVET--EKVLDIIYQPQAIFRVRAVTRCTSS 108
Query: 89 FQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK 147
+ + V +V P + G + WDL T+ + I+ P GK
Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 168
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKF-----SPDSTMLVTTSGDC 202
+A+ G +W S + + HSK+ + +P+ + ++S D
Sbjct: 169 KLASGCKNGQILLWDPSTGKQ---VGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDG 225
Query: 203 SAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYC 262
S +IW T+ R L TQ V + D L++ S D ++W G L R
Sbjct: 226 SVRIWDTTAGRCERILTGHTQS-VTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQ 283
Query: 263 GHQKAITALA 272
GH + +A
Sbjct: 284 GHGHWVNTMA 293
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ HS+ + FSP L + SGD + + W S + + WV +++ D
Sbjct: 109 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLST-ETPHFTCKGHRHWVLSISWSPDG 167
Query: 236 RFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAFK 274
+ L +G + LW+ G + R GH K IT L+++
Sbjct: 168 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWE 207
>AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens
cDNA FLJ10458 fis, clone NT2RP1001457, highly similar to
Homo sapiens partial mRNA for beta-transducin family
protein. ).
Length = 485
Score = 61.3 bits (142), Expect = 4e-09
Identities = 54/244 (22%), Positives = 102/244 (41%), Gaps = 9/244 (3%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+R++D ++ + + T S R G +Y+ +D T ++W RA C+
Sbjct: 228 VRIWDTTAGRCERILTGHTQSVTCLRWG---GDGLLYSASQDRTIKVW--RAHDGVLCRT 282
Query: 88 IFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK 147
+ VN + L D + + + + Q + E S ++ +
Sbjct: 283 LQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNLVRGQGPE 342
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + ++ ++WS + P +T H + FSPDS ++ + S D S K+W
Sbjct: 343 RLVSGSDDFTLFLWSPAEDKK---PLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 399
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKA 267
L LR V+ A++ DSR L +GSSDS ++W+++ L + GH
Sbjct: 400 DGRTGKYLASLRGHVAA-VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADE 458
Query: 268 ITAL 271
+ A+
Sbjct: 459 VYAV 462
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 9/141 (6%)
Query: 136 SIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
++ +A P GK +A+ + W LS + PH K H + L +SPD L
Sbjct: 116 AVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCK----GHRHWVLSISWSPDGKKL 171
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWV----WDAAFTL-DSRFLFTGSSDSYARLW 250
+ + +W S + +W+ W+ + R++ + S D R+W
Sbjct: 172 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 231
Query: 251 NIERGTLEREYCGHQKAITAL 271
+ G ER GH +++T L
Sbjct: 232 DTTAGRCERILTGHTQSVTCL 252
Score = 46.4 bits (105), Expect = 1e-04
Identities = 58/250 (23%), Positives = 96/250 (38%), Gaps = 17/250 (6%)
Query: 33 LSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPR----TRCQKI 88
L+ +P P+ F ++ VS +G + T E I+ P+A R TRC
Sbjct: 52 LAQEDPLPLAFFVHDAEIVSSLGKTLESQAVET--EKVLDIIYQPQAIFRVRAVTRCTSS 109
Query: 89 FQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK 147
+ + V +V P + G + WDL T+ + I+ P GK
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 169
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKF-----SPDSTMLVTTSGDC 202
+A+ G +W S + + HSK+ + +P+ + ++S D
Sbjct: 170 KLASGCKNGQILLWDPSTGKQ---VGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDG 226
Query: 203 SAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYC 262
S +IW T+ R L TQ V + D L++ S D ++W G L R
Sbjct: 227 SVRIWDTTAGRCERILTGHTQS-VTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQ 284
Query: 263 GHQKAITALA 272
GH + +A
Sbjct: 285 GHGHWVNTMA 294
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ HS+ + FSP L + SGD + + W S + + WV +++ D
Sbjct: 110 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLST-ETPHFTCKGHRHWVLSISWSPDG 168
Query: 236 RFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAFK 274
+ L +G + LW+ G + R GH K IT L+++
Sbjct: 169 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWE 208
>M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human
signal-transducing guanine nucleotide-binding regulatory
(G) protein beta subunit mRNA, complete cds. ).
Length = 340
Score = 60.9 bits (141), Expect = 5e-09
Identities = 39/181 (21%), Positives = 74/181 (40%), Gaps = 2/181 (1%)
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
A + A+ D ++ Q G + IWD T IP + + A +G +A
Sbjct: 56 AKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSGNFVACG 115
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
C ++SL + + + + H+ Y C+F D ++T+SGD + +W
Sbjct: 116 GLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFL-DDNQIITSSGDTTCALWDIETG 174
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
+ V + + R +G+ D+ +LW++ + + GH+ I A+A
Sbjct: 175 QQTVGFAGHSGD-VMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVA 233
Query: 273 F 273
F
Sbjct: 234 F 234
Score = 48.8 bits (111), Expect = 2e-05
Identities = 43/199 (21%), Positives = 80/199 (40%), Gaps = 16/199 (8%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ ++ ++G L+D+ + F S +V + NG +G D + +
Sbjct: 152 LDDNQIITSSGDTTCALWDIETGQQ--TVGFAGHSGDVMSLSLAPNGRTFVSGACDASIK 209
Query: 74 IWDPRAAPRTRCQKIF-QVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R + C++ F ++ +NAV P+ G ++DL+ DQ +
Sbjct: 210 LWDVR---DSMCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSH 266
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCKFS 189
I +A +G+++ A + NC +W ++ G + + A + C
Sbjct: 267 DNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGD------RAGVLAGHDNRVSCLGV 320
Query: 190 PDSTMLVTT-SGDCSAKIW 207
D M V T S D KIW
Sbjct: 321 TDDGMAVATGSWDSFLKIW 339
Score = 42.7 bits (96), Expect = 0.001
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P G+ + + +W
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWD 212
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ H F P+ T S D + +++ +D LL +
Sbjct: 213 VRDS----MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ AF+ R L G D +W+ +G GH ++ L D
Sbjct: 269 IICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTD 322
Score = 36.3 bits (80), Expect = 0.12
Identities = 41/192 (21%), Positives = 67/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L P+ + G I +WD++
Sbjct: 159 TSSGDTTCALWDIETGQQT--VGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDS 216
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I +A P G ++ C ++ L + + +S +
Sbjct: 217 MCRQTFIGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRAD-------QELLMYSHDNI 269
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + IW L R V T D +
Sbjct: 270 ICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNR-VSCLGVTDDGMAVA 328
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 329 TGSWDSFLKIWN 340
Score = 35.1 bits (77), Expect = 0.27
Identities = 31/156 (19%), Positives = 61/156 (39%), Gaps = 4/156 (2%)
Query: 9 VNSLEISPT--SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V SL ++P + V+ A I+L+D+ + TF +++ V F NG TG
Sbjct: 187 VMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQ--TFIGHESDINAVAFFPNGYAFTTG 244
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
+D T R++D RA + + +V ++ G +IWD
Sbjct: 245 SDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDR 304
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
++ + + + + G +A + +W+
Sbjct: 305 AGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 340
>U72342-1|AAC51111.1| 410|Homo sapiens platelet activating factor
acetylhydrolase, brain isoform, 45 kDa subunit protein.
Length = 410
Score = 59.7 bits (138), Expect = 1e-08
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 5/182 (2%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
++PV V+ HP S ++ + I +WD +T E+ + S+QDI+ D +GK++A+
Sbjct: 108 RSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLAS 167
Query: 152 VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
+ +W G + H H P+ +V+ S D + K+W
Sbjct: 168 CSADMTIKLWDFQGF--ECIRTMH--GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++ + WV D + + S+D R+W + + E H+ + +
Sbjct: 224 GYCVKTF-TGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
Query: 272 AF 273
++
Sbjct: 283 SW 284
Score = 44.4 bits (100), Expect = 4e-04
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P P K ++ H R F P +++V+ S D + K+W R L+ T V
Sbjct: 96 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS-VQ 154
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
D +F + L + S+D +LW+ + R GH ++++A
Sbjct: 155 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA 199
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/242 (19%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+RV F + M + ED T ++WD R K V + +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISFDHSGKLLASC 168
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
I +WD + + + + + ++ +AI P G + + + +W + Q +
Sbjct: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV--QTGYC 226
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR-----DTQRW 225
V K T H ++ + + D T++ + S D + ++W + ELR + W
Sbjct: 227 V--KTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
Query: 226 VWDAAFTLDSR--------------FLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+++++ S FL +GS D ++W++ G GH + +
Sbjct: 285 APESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344
Query: 272 AF 273
F
Sbjct: 345 LF 346
Score = 42.7 bits (96), Expect = 0.001
Identities = 50/271 (18%), Positives = 108/271 (39%), Gaps = 21/271 (7%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
MV+A+ I+++D + D T + + +V + F +G + + D T ++WD +
Sbjct: 123 MVSASEDATIKVWDYETG--DFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
R V++V + P+ I+ + I +W+++T + ++
Sbjct: 181 GFECIRTMHGHDHN--VSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVR 238
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHI--------TAHSKYALRCKFSP 190
+ + G ++A+ +N VW ++ + ++H S Y+ + +
Sbjct: 239 MVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATG 298
Query: 191 DST--------MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
T L++ S D + K+W S L L WV F +F+ + +
Sbjct: 299 SETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH-DNWVRGVLFHSGGKFILSCA 357
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALAF 273
D R+W+ + + H+ +T+L F
Sbjct: 358 DDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 388
Score = 30.7 bits (66), Expect = 5.9
Identities = 19/101 (18%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G + I +WD+ T + + ++ + GK + + + VW +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
K + AH + F + +VT S D + K+W
Sbjct: 371 RC----MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
>M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transducin
beta-1 subunit mRNA, 3' end. ).
Length = 247
Score = 59.7 bits (138), Expect = 1e-08
Identities = 33/143 (23%), Positives = 63/143 (44%), Gaps = 2/143 (1%)
Query: 131 PEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
P + + A P+G +A C +++L + + + + H+ Y C+F
Sbjct: 1 PLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLD 60
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
D+ +VT+SGD + +W T V + D+R +G+ D+ A+LW
Sbjct: 61 DN-QIVTSSGDTTCALWDIETGQQTTTFTGHTGD-VMSLSLAPDTRLFVSGACDASAKLW 118
Query: 251 NIERGTLEREYCGHQKAITALAF 273
++ G + + GH+ I A+ F
Sbjct: 119 DVREGMCRQTFTGHESDINAICF 141
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 59 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 116
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 117 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 173
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 174 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 229
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 230 DGMAVATGSWDSFLKIW 246
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 60 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 119
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 120 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 175
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 176 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 229
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 66 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 123
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 124 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 176
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 177 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 235
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 236 TGSWDSFLKIWN 247
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 136 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 195
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 196 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 247
>L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 59.7 bits (138), Expect = 1e-08
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 5/182 (2%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
++PV V+ HP S ++ + I +WD +T E+ + S+QDI+ D +GK++A+
Sbjct: 108 RSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLAS 167
Query: 152 VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
+ +W G + H H P+ +V+ S D + K+W
Sbjct: 168 CSADMTIKLWDFQGF--ECIRTMH--GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++ + WV D + + S+D R+W + + E H+ + +
Sbjct: 224 GYCVKTF-TGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
Query: 272 AF 273
++
Sbjct: 283 SW 284
Score = 44.4 bits (100), Expect = 4e-04
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P P K ++ H R F P +++V+ S D + K+W R L+ T V
Sbjct: 96 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS-VQ 154
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
D +F + L + S+D +LW+ + R GH ++++A
Sbjct: 155 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA 199
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/242 (19%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+RV F + M + ED T ++WD R K V + +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISFDHSGKLLASC 168
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
I +WD + + + + + ++ +AI P G + + + +W + Q +
Sbjct: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV--QTGYC 226
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR-----DTQRW 225
V K T H ++ + + D T++ + S D + ++W + ELR + W
Sbjct: 227 V--KTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
Query: 226 VWDAAFTLDSR--------------FLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+++++ S FL +GS D ++W++ G GH + +
Sbjct: 285 APESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344
Query: 272 AF 273
F
Sbjct: 345 LF 346
Score = 42.7 bits (96), Expect = 0.001
Identities = 50/271 (18%), Positives = 108/271 (39%), Gaps = 21/271 (7%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
MV+A+ I+++D + D T + + +V + F +G + + D T ++WD +
Sbjct: 123 MVSASEDATIKVWDYETG--DFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
R V++V + P+ I+ + I +W+++T + ++
Sbjct: 181 GFECIRTMHGHDHN--VSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVR 238
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHI--------TAHSKYALRCKFSP 190
+ + G ++A+ +N VW ++ + ++H S Y+ + +
Sbjct: 239 MVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATG 298
Query: 191 DST--------MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
T L++ S D + K+W S L L WV F +F+ + +
Sbjct: 299 SETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH-DNWVRGVLFHSGGKFILSCA 357
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALAF 273
D R+W+ + + H+ +T+L F
Sbjct: 358 DDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 388
Score = 30.7 bits (66), Expect = 5.9
Identities = 19/101 (18%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G + I +WD+ T + + ++ + GK + + + VW +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
K + AH + F + +VT S D + K+W
Sbjct: 371 RC----MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
>L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 59.7 bits (138), Expect = 1e-08
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 5/182 (2%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
++PV V+ HP S ++ + I +WD +T E+ + S+QDI+ D +GK++A+
Sbjct: 108 RSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLAS 167
Query: 152 VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
+ +W G + H H P+ +V+ S D + K+W
Sbjct: 168 CSADMTIKLWDFQGF--ECIRTMH--GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++ + WV D + + S+D R+W + + E H+ + +
Sbjct: 224 GYCVKTF-TGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
Query: 272 AF 273
++
Sbjct: 283 SW 284
Score = 44.4 bits (100), Expect = 4e-04
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P P K ++ H R F P +++V+ S D + K+W R L+ T V
Sbjct: 96 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS-VQ 154
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
D +F + L + S+D +LW+ + R GH ++++A
Sbjct: 155 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA 199
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/242 (19%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+RV F + M + ED T ++WD R K V + +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISFDHSGKLLASC 168
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
I +WD + + + + + ++ +AI P G + + + +W + Q +
Sbjct: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV--QTGYC 226
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR-----DTQRW 225
V K T H ++ + + D T++ + S D + ++W + ELR + W
Sbjct: 227 V--KTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
Query: 226 VWDAAFTLDSR--------------FLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+++++ S FL +GS D ++W++ G GH + +
Sbjct: 285 APESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344
Query: 272 AF 273
F
Sbjct: 345 LF 346
Score = 42.7 bits (96), Expect = 0.001
Identities = 50/271 (18%), Positives = 108/271 (39%), Gaps = 21/271 (7%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
MV+A+ I+++D + D T + + +V + F +G + + D T ++WD +
Sbjct: 123 MVSASEDATIKVWDYETG--DFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
R V++V + P+ I+ + I +W+++T + ++
Sbjct: 181 GFECIRTMHGHDHN--VSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVR 238
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHI--------TAHSKYALRCKFSP 190
+ + G ++A+ +N VW ++ + ++H S Y+ + +
Sbjct: 239 MVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATG 298
Query: 191 DST--------MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
T L++ S D + K+W S L L WV F +F+ + +
Sbjct: 299 SETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH-DNWVRGVLFHSGGKFILSCA 357
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALAF 273
D R+W+ + + H+ +T+L F
Sbjct: 358 DDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 388
Score = 30.7 bits (66), Expect = 5.9
Identities = 19/101 (18%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G + I +WD+ T + + ++ + GK + + + VW +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
K + AH + F + +VT S D + K+W
Sbjct: 371 RC----MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
>BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating factor
acetylhydrolase, isoform Ib, alpha subunit 45kDa
protein.
Length = 410
Score = 59.7 bits (138), Expect = 1e-08
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 5/182 (2%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
++PV V+ HP S ++ + I +WD +T E+ + S+QDI+ D +GK++A+
Sbjct: 108 RSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLAS 167
Query: 152 VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
+ +W G + H H P+ +V+ S D + K+W
Sbjct: 168 CSADMTIKLWDFQGF--ECIRTMH--GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++ + WV D + + S+D R+W + + E H+ + +
Sbjct: 224 GYCVKTF-TGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
Query: 272 AF 273
++
Sbjct: 283 SW 284
Score = 44.4 bits (100), Expect = 4e-04
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P P K ++ H R F P +++V+ S D + K+W R L+ T V
Sbjct: 96 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS-VQ 154
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
D +F + L + S+D +LW+ + R GH ++++A
Sbjct: 155 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA 199
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/242 (19%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+RV F + M + ED T ++WD R K V + +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISFDHSGKLLASC 168
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
I +WD + + + + + ++ +AI P G + + + +W + Q +
Sbjct: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV--QTGYC 226
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR-----DTQRW 225
V K T H ++ + + D T++ + S D + ++W + ELR + W
Sbjct: 227 V--KTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
Query: 226 VWDAAFTLDSR--------------FLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+++++ S FL +GS D ++W++ G GH + +
Sbjct: 285 APESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344
Query: 272 AF 273
F
Sbjct: 345 LF 346
Score = 42.7 bits (96), Expect = 0.001
Identities = 50/271 (18%), Positives = 108/271 (39%), Gaps = 21/271 (7%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
MV+A+ I+++D + D T + + +V + F +G + + D T ++WD +
Sbjct: 123 MVSASEDATIKVWDYETG--DFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
R V++V + P+ I+ + I +W+++T + ++
Sbjct: 181 GFECIRTMHGHDHN--VSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVR 238
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHI--------TAHSKYALRCKFSP 190
+ + G ++A+ +N VW ++ + ++H S Y+ + +
Sbjct: 239 MVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATG 298
Query: 191 DST--------MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
T L++ S D + K+W S L L WV F +F+ + +
Sbjct: 299 SETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH-DNWVRGVLFHSGGKFILSCA 357
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALAF 273
D R+W+ + + H+ +T+L F
Sbjct: 358 DDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 388
Score = 30.7 bits (66), Expect = 5.9
Identities = 19/101 (18%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G + I +WD+ T + + ++ + GK + + + VW +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
K + AH + F + +VT S D + K+W
Sbjct: 371 RC----MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
>BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61
protein.
Length = 305
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/206 (24%), Positives = 83/206 (40%), Gaps = 9/206 (4%)
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D R+WD + + V A A PD + G G ++I+ +++ + E
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLA--FSPDSQYLATGTHVGKVNIFGVESGKKEY 142
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCK 187
+ I IA P GK +A+ G ++ ++ G+ H + H+
Sbjct: 143 SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-----LEGHAMPIRSLT 197
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
FSPDS +LVT S D KI+ L L WV + AF D + SSD
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHAS-WVLNVAFCPDDTHFVSSSSDKSV 256
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
++W++ T + HQ + + +
Sbjct: 257 KVWDVGTRTCVHTFFDHQDQVWGVKY 282
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/201 (21%), Positives = 86/201 (42%), Gaps = 10/201 (4%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++IS T +AA+ HIRL+DL N + + + + + F + ++ TG
Sbjct: 67 VVSVDISHTLPIAASSSLDAHIRLWDLE--NGKQIKSIDAGPVDAWTLAFSPDSQYLATG 124
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
I+ + + + + ++ PD + G GII+I+D+ T +
Sbjct: 125 THVGKVNIFGVESGKKE--YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKL 182
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
+ I+ + P +++ ++ G ++ + H ++ H+ + L
Sbjct: 183 LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQ----HANLAGTLSGHASWVLNV 238
Query: 187 KFSPDSTMLVTTSGDCSAKIW 207
F PD T V++S D S K+W
Sbjct: 239 AFCPDDTHFVSSSSDKSVKVW 259
>AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21101 fis, clone CAS04682. ).
Length = 305
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/206 (24%), Positives = 83/206 (40%), Gaps = 9/206 (4%)
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D R+WD + + V A A PD + G G ++I+ +++ + E
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLA--FSPDSQYLATGTHVGKVNIFGVESGKKEY 142
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCK 187
+ I IA P GK +A+ G ++ ++ G+ H + H+
Sbjct: 143 SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-----LEGHAMPIRSLT 197
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
FSPDS +LVT S D KI+ L L WV + AF D + SSD
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHAS-WVLNVAFCPDDTHFVSSSSDKSV 256
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
++W++ T + HQ + + +
Sbjct: 257 KVWDVGTRTCVHTFFDHQDQVWGVKY 282
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/201 (21%), Positives = 86/201 (42%), Gaps = 10/201 (4%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++IS T +AA+ HIRL+DL N + + + + + F + ++ TG
Sbjct: 67 VVSVDISHTLPIAASSSLDAHIRLWDLE--NGKQIKSIDAGPVDAWTLAFSPDSQYLATG 124
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
I+ + + + + ++ PD + G GII+I+D+ T +
Sbjct: 125 THVGKVNIFGVESGKKE--YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKL 182
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
+ I+ + P +++ ++ G ++ + H ++ H+ + L
Sbjct: 183 LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQ----HANLAGTLSGHASWVLNV 238
Query: 187 KFSPDSTMLVTTSGDCSAKIW 207
F PD T V++S D S K+W
Sbjct: 239 AFCPDDTHFVSSSSDKSVKVW 259
>AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating factor
acetyl hydrolase isoform Ib alpha subunit protein.
Length = 410
Score = 59.7 bits (138), Expect = 1e-08
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 5/182 (2%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
++PV V+ HP S ++ + I +WD +T E+ + S+QDI+ D +GK++A+
Sbjct: 108 RSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLAS 167
Query: 152 VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
+ +W G + H H P+ +V+ S D + K+W
Sbjct: 168 CSADMTIKLWDFQGF--ECIRTMH--GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++ + WV D + + S+D R+W + + E H+ + +
Sbjct: 224 GYCVKTF-TGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
Query: 272 AF 273
++
Sbjct: 283 SW 284
Score = 44.4 bits (100), Expect = 4e-04
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P P K ++ H R F P +++V+ S D + K+W R L+ T V
Sbjct: 96 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS-VQ 154
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
D +F + L + S+D +LW+ + R GH ++++A
Sbjct: 155 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA 199
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/242 (19%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+RV F + M + ED T ++WD R K V + +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISFDHSGKLLASC 168
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
I +WD + + + + + ++ +AI P G + + + +W + Q +
Sbjct: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV--QTGYC 226
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR-----DTQRW 225
V K T H ++ + + D T++ + S D + ++W + ELR + W
Sbjct: 227 V--KTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
Query: 226 VWDAAFTLDSR--------------FLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+++++ S FL +GS D ++W++ G GH + +
Sbjct: 285 APESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344
Query: 272 AF 273
F
Sbjct: 345 LF 346
Score = 42.7 bits (96), Expect = 0.001
Identities = 50/271 (18%), Positives = 108/271 (39%), Gaps = 21/271 (7%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
MV+A+ I+++D + D T + + +V + F +G + + D T ++WD +
Sbjct: 123 MVSASEDATIKVWDYETG--DFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
R V++V + P+ I+ + I +W+++T + ++
Sbjct: 181 GFECIRTMHGHDHN--VSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVR 238
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHI--------TAHSKYALRCKFSP 190
+ + G ++A+ +N VW ++ + ++H S Y+ + +
Sbjct: 239 MVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATG 298
Query: 191 DST--------MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
T L++ S D + K+W S L L WV F +F+ + +
Sbjct: 299 SETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH-DNWVRGVLFHSGGKFILSCA 357
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALAF 273
D R+W+ + + H+ +T+L F
Sbjct: 358 DDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 388
Score = 30.7 bits (66), Expect = 5.9
Identities = 19/101 (18%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G + I +WD+ T + + ++ + GK + + + VW +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
K + AH + F + +VT S D + K+W
Sbjct: 371 RC----MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
>AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination
protein REC14 protein.
Length = 305
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/206 (24%), Positives = 83/206 (40%), Gaps = 9/206 (4%)
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D R+WD + + V A A PD + G G ++I+ +++ + E
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLA--FSPDSQYLATGTHVGKVNIFGVESGKKEY 142
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCK 187
+ I IA P GK +A+ G ++ ++ G+ H + H+
Sbjct: 143 SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-----LEGHAMPIRSLT 197
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
FSPDS +LVT S D KI+ L L WV + AF D + SSD
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHAS-WVLNVAFCPDDTHFVSSSSDKSV 256
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
++W++ T + HQ + + +
Sbjct: 257 KVWDVGTRTCVHTFFDHQDQVWGVKY 282
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/201 (21%), Positives = 86/201 (42%), Gaps = 10/201 (4%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++IS T +AA+ HIRL+DL N + + + + + F + ++ TG
Sbjct: 67 VVSVDISHTLPIAASSSLDAHIRLWDLE--NGKQIKSIDAGPVDAWTLAFSPDSQYLATG 124
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
I+ + + + + ++ PD + G GII+I+D+ T +
Sbjct: 125 THVGKVNIFGVESGKKE--YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKL 182
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
+ I+ + P +++ ++ G ++ + H ++ H+ + L
Sbjct: 183 LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQ----HANLAGTLSGHASWVLNV 238
Query: 187 KFSPDSTMLVTTSGDCSAKIW 207
F PD T V++S D S K+W
Sbjct: 239 AFCPDDTHFVSSSSDKSVKVW 259
>AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 59.7 bits (138), Expect = 1e-08
Identities = 38/182 (20%), Positives = 76/182 (41%), Gaps = 5/182 (2%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
++PV V+ HP S ++ + I +WD +T E+ + S+QDI+ D +GK++A+
Sbjct: 108 RSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLAS 167
Query: 152 VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
+ +W G + H H P+ +V+ S D + K+W
Sbjct: 168 CSADMTIKLWDFQGF--ECIRTMH--GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++ + WV D + + S+D R+W + + E H+ + +
Sbjct: 224 GYCVKTF-TGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
Query: 272 AF 273
++
Sbjct: 283 SW 284
Score = 44.4 bits (100), Expect = 4e-04
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
P P K ++ H R F P +++V+ S D + K+W R L+ T V
Sbjct: 96 PRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS-VQ 154
Query: 228 DAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
D +F + L + S+D +LW+ + R GH ++++A
Sbjct: 155 DISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVA 199
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/242 (19%), Positives = 92/242 (38%), Gaps = 25/242 (10%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+RV F + M + ED T ++WD R K V + +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLK--GHTDSVQDISFDHSGKLLASC 168
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
I +WD + + + + + ++ +AI P G + + + +W + Q +
Sbjct: 169 SADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEV--QTGYC 226
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR-----DTQRW 225
V K T H ++ + + D T++ + S D + ++W + ELR + W
Sbjct: 227 V--KTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 284
Query: 226 VWDAAFTLDSR--------------FLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+++++ S FL +GS D ++W++ G GH + +
Sbjct: 285 APESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGV 344
Query: 272 AF 273
F
Sbjct: 345 LF 346
Score = 42.7 bits (96), Expect = 0.001
Identities = 50/271 (18%), Positives = 108/271 (39%), Gaps = 21/271 (7%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
MV+A+ I+++D + D T + + +V + F +G + + D T ++WD +
Sbjct: 123 MVSASEDATIKVWDYETG--DFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
R V++V + P+ I+ + I +W+++T + ++
Sbjct: 181 GFECIRTMHGHDHN--VSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVR 238
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHI--------TAHSKYALRCKFSP 190
+ + G ++A+ +N VW ++ + ++H S Y+ + +
Sbjct: 239 MVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATG 298
Query: 191 DST--------MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
T L++ S D + K+W S L L WV F +F+ + +
Sbjct: 299 SETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH-DNWVRGVLFHSGGKFILSCA 357
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALAF 273
D R+W+ + + H+ +T+L F
Sbjct: 358 DDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 388
Score = 30.7 bits (66), Expect = 5.9
Identities = 19/101 (18%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G + I +WD+ T + + ++ + GK + + + VW +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
K + AH + F + +VT S D + K+W
Sbjct: 371 RC----MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
>AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 59.7 bits (138), Expect = 1e-08
Identities = 50/206 (24%), Positives = 83/206 (40%), Gaps = 9/206 (4%)
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D R+WD + + V A A PD + G G ++I+ +++ + E
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLA--FSPDSQYLATGTHVGKVNIFGVESGKKEY 142
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCK 187
+ I IA P GK +A+ G ++ ++ G+ H + H+
Sbjct: 143 SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-----LEGHAMPIRSLT 197
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
FSPDS +LVT S D KI+ L L WV + AF D + SSD
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHAS-WVLNVAFCPDDTHFVSSSSDKSV 256
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
++W++ T + HQ + + +
Sbjct: 257 KVWDVGTRTCVHTFFDHQDQVWGVKY 282
Score = 52.4 bits (120), Expect = 2e-06
Identities = 43/201 (21%), Positives = 86/201 (42%), Gaps = 10/201 (4%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++IS T +AA+ HIRL+DL N + + + + + F + ++ TG
Sbjct: 67 VVSVDISHTLPIAASSSLDAHIRLWDLE--NGKQIKSIDAGPVDAWTLAFSPDSQYLATG 124
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
I+ + + + + ++ PD + G GII+I+D+ T +
Sbjct: 125 THVGKVNIFGVESGKKE--YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKL 182
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
+ I+ + P +++ ++ G ++ + H ++ H+ + L
Sbjct: 183 LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQ----HANLAGTLSGHASWVLNV 238
Query: 187 KFSPDSTMLVTTSGDCSAKIW 207
F PD T V++S D S K+W
Sbjct: 239 AFCPDDTHFVSSSSDKSVKVW 259
>AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog
variant protein.
Length = 487
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/244 (22%), Positives = 101/244 (41%), Gaps = 9/244 (3%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQK 87
+R++D ++ + + T S R G +Y+ +D T ++W RA C+
Sbjct: 230 VRIWDTTAGRCERILTGHTQSVTCLRWG---GDGLLYSASQDRTIKVW--RAHDGVLCRT 284
Query: 88 IFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK 147
+ VN + L D + + + Q + E S ++ +
Sbjct: 285 LQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGFLQELKERALSRYNLVRGQGPE 344
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + ++ ++WS + P +T H + FSPDS ++ + S D S K+W
Sbjct: 345 RLVSGSDDFTLFLWSPAEDKK---PLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLW 401
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKA 267
L LR V+ A++ DSR L +GSSDS ++W+++ L + GH
Sbjct: 402 DGRTGKYLASLRGHVAA-VYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHADE 460
Query: 268 ITAL 271
+ A+
Sbjct: 461 VYAV 464
Score = 53.2 bits (122), Expect = 1e-06
Identities = 33/141 (23%), Positives = 58/141 (41%), Gaps = 9/141 (6%)
Query: 136 SIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
++ +A P GK +A+ + W LS + PH K H + L +SPD L
Sbjct: 118 AVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCK----GHRHWVLSISWSPDGKKL 173
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWV----WDAAFTL-DSRFLFTGSSDSYARLW 250
+ + +W S + +W+ W+ + R++ + S D R+W
Sbjct: 174 ASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDGSVRIW 233
Query: 251 NIERGTLEREYCGHQKAITAL 271
+ G ER GH +++T L
Sbjct: 234 DTTAGRCERILTGHTQSVTCL 254
Score = 46.4 bits (105), Expect = 1e-04
Identities = 58/250 (23%), Positives = 96/250 (38%), Gaps = 17/250 (6%)
Query: 33 LSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPR----TRCQKI 88
L+ +P P+ F ++ VS +G + T E I+ P+A R TRC
Sbjct: 54 LAQEDPLPLAFFVHDAEIVSSLGKTLESQAVET--EKVLDIIYQPQAIFRVRAVTRCTSS 111
Query: 89 FQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK 147
+ + V +V P + G + WDL T+ + I+ P GK
Sbjct: 112 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGK 171
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKF-----SPDSTMLVTTSGDC 202
+A+ G +W S + + HSK+ + +P+ + ++S D
Sbjct: 172 KLASGCKNGQILLWDPSTGKQ---VGRTLAGHSKWITGLSWEPLHANPECRYVASSSKDG 228
Query: 203 SAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYC 262
S +IW T+ R L TQ V + D L++ S D ++W G L R
Sbjct: 229 SVRIWDTTAGRCERILTGHTQS-VTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCRTLQ 286
Query: 263 GHQKAITALA 272
GH + +A
Sbjct: 287 GHGHWVNTMA 296
Score = 42.7 bits (96), Expect = 0.001
Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ HS+ + FSP L + SGD + + W S + + WV +++ D
Sbjct: 112 LEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLST-ETPHFTCKGHRHWVLSISWSPDG 170
Query: 236 RFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAFK 274
+ L +G + LW+ G + R GH K IT L+++
Sbjct: 171 KKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWE 210
>CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein.
Length = 305
Score = 59.3 bits (137), Expect = 1e-08
Identities = 50/206 (24%), Positives = 83/206 (40%), Gaps = 9/206 (4%)
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D R+WD + + V A A PD + G G ++I+ +++ + E
Sbjct: 85 DAHIRLWDLENGKQIKSIDAGPVDAWTLA--FSPDSQYLATGTHVGKVNIFGVESGKKEY 142
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCK 187
+ I IA P GK +A+ G ++ ++ G+ H + H+
Sbjct: 143 SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT-----LEGHAMPIRSLT 197
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
FSPDS +LVT S D KI+ L L WV + AF D + SSD
Sbjct: 198 FSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHAS-WVLNVAFCPDDTHFVSSSSDKNV 256
Query: 248 RLWNIERGTLEREYCGHQKAITALAF 273
++W++ T + HQ + + +
Sbjct: 257 KVWDVGTRTCVHTFFDHQDQVWGVKY 282
Score = 50.0 bits (114), Expect = 9e-06
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 10/201 (4%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++IS T +AA+ HIRL+DL N + + + + + F + ++ TG
Sbjct: 67 VVSVDISHTLPIAASSSLDAHIRLWDLE--NGKQIKSIDAGPVDAWTLAFSPDSQYLATG 124
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
I+ + + + + ++ PD + G GII+I+D+ T +
Sbjct: 125 THVGKVNIFGVESGKKE--YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKL 182
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
+ I+ + P +++ ++ G ++ + H + H+ + L
Sbjct: 183 LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQ----HANLAGTLGGHASWVLNV 238
Query: 187 KFSPDSTMLVTTSGDCSAKIW 207
F PD T V++S D + K+W
Sbjct: 239 AFCPDDTHFVSSSSDKNVKVW 259
>AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1
isoform 1 variant protein.
Length = 421
Score = 59.3 bits (137), Expect = 1e-08
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 6/163 (3%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNCYVW 161
DQ + G +G I IWD+ T + + + ++D+ P G + + + + VW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L K + H + C FSPDS+ML + + +W + ++R+L
Sbjct: 199 DLKDDGNM---MKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL-EG 254
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGH 264
V F+ D L T S D+ +W+ G + E+ GH
Sbjct: 255 RHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GH 296
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
++ H++ F+PD S +LV+ S D + ++W D + ++ R Q WV+ AF+
Sbjct: 165 NLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP 224
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
DS L + + LWN+++ T+ R+ G + A F
Sbjct: 225 DSSMLCSVGASKAVFLWNMDKYTMIRKLEGRHHDVVACDF 264
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/215 (22%), Positives = 83/215 (38%), Gaps = 20/215 (9%)
Query: 53 RVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-D 111
R F ++ + TG + +IWD + + + V + PD S I+V
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTG-KLLLNLVDHTEV-VRDLTFAPDGSLILVSAS 190
Query: 112 QSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ + +WDLK D N + + + A P M+ +V ++W++ +
Sbjct: 191 RDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMD---KYT 247
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR---------- 220
+ +K H + C FSPD +L T S D IW + +L E
Sbjct: 248 MIRKLEGRHHD-VVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFA 306
Query: 221 --DTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
RWV +F+ D + + + D R W I+
Sbjct: 307 GGANDRWVRSVSFSHDGLHVASLADDKMVRFWRID 341
>BC025392-1|AAH25392.1| 620|Homo sapiens WD repeat domain 16
protein.
Length = 620
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 7/179 (3%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDL--KTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
V A+ D +++ G G + +W + +T + E+ + E ++S+ I + +
Sbjct: 420 VTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTA 479
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+ G C +W L + + I A++ + C + P+ ++T+ D W D
Sbjct: 480 STDGTCIIWDLVRLRRNQM----ILANTLFQCVC-YHPEEFQIITSGTDRKIAYWEVFDG 534
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++REL + T + TG +D ++W+ G + GH IT +
Sbjct: 535 TVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRI 593
Score = 39.5 bits (88), Expect = 0.013
Identities = 39/192 (20%), Positives = 69/192 (35%), Gaps = 10/192 (5%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
+++ G +R++ + ++ +VS + ++N T D T IWD
Sbjct: 432 VISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWD-- 489
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN-EQLIPEAEASI 137
R R ++ V HP++ QI+ I W++ +L SI
Sbjct: 490 -LVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSI 548
Query: 138 QDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCKFSPDSTMLV 196
+ I G N VW + G+ H HS R + SP + +V
Sbjct: 549 NGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVG-----VGHSGNITRIRISPGNQYIV 603
Query: 197 TTSGDCSAKIWR 208
+ S D + W+
Sbjct: 604 SVSADGAILRWK 615
>BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS
box-containing 1 protein.
Length = 421
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 6/163 (3%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNCYVW 161
DQ + G +G I IWD+ T + + + ++D+ P G + + + + VW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L K + H + C FSPDS+ML + + +W + ++R+L
Sbjct: 199 DLKDDGNM---MKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL-EG 254
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGH 264
V F+ D L T S D+ +W+ G + E+ GH
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GH 296
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
++ H++ F+PD S +LV+ S D + ++W D + ++ R Q WV+ AF+
Sbjct: 165 NLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP 224
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
DS L + + LWN+++ T+ R+ GH + A F
Sbjct: 225 DSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDF 264
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/215 (22%), Positives = 84/215 (39%), Gaps = 20/215 (9%)
Query: 53 RVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-D 111
R F ++ + TG + +IWD + + + V + PD S I+V
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTG-KLLLNLVDHTEV-VRDLTFAPDGSLILVSAS 190
Query: 112 QSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ + +WDLK D N + + + A P M+ +V ++W++ +
Sbjct: 191 RDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMD---KYT 247
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR---------- 220
+ +K + H + C FSPD +L T S D IW + +L E
Sbjct: 248 MIRK-LEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFA 306
Query: 221 --DTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
RWV +F+ D + + + D R W I+
Sbjct: 307 GGANDRWVRSVSFSHDGLHVASLADDKMVRFWRID 341
>AK094847-1|BAC04435.1| 630|Homo sapiens protein ( Homo sapiens
cDNA FLJ37528 fis, clone BRCAN2012408. ).
Length = 630
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 7/179 (3%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDL--KTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
V A+ D +++ G G + +W + +T + E+ + E ++S+ I + +
Sbjct: 430 VTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTA 489
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+ G C +W L + + I A++ + C + P+ ++T+ D W D
Sbjct: 490 STDGTCIIWDLVRLRRNQM----ILANTLFQCVC-YHPEEFQIITSGTDRKIAYWEVFDG 544
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++REL + T + TG +D ++W+ G + GH IT +
Sbjct: 545 TVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRI 603
Score = 39.5 bits (88), Expect = 0.013
Identities = 39/192 (20%), Positives = 69/192 (35%), Gaps = 10/192 (5%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
+++ G +R++ + ++ +VS + ++N T D T IWD
Sbjct: 442 VISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWD-- 499
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN-EQLIPEAEASI 137
R R ++ V HP++ QI+ I W++ +L SI
Sbjct: 500 -LVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSI 558
Query: 138 QDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCKFSPDSTMLV 196
+ I G N VW + G+ H HS R + SP + +V
Sbjct: 559 NGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVG-----VGHSGNITRIRISPGNQYIV 613
Query: 197 TTSGDCSAKIWR 208
+ S D + W+
Sbjct: 614 SVSADGAILRWK 625
>AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens
cDNA FLJ90436 fis, clone NT2RP3000820, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC
2.7.1.-). ).
Length = 421
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 6/163 (3%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNCYVW 161
DQ + G +G I IWD+ T + + + ++D+ P G + + + + VW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L K + H + C FSPDS+ML + + +W + ++R+L
Sbjct: 199 DLKDDGNM---MKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL-EG 254
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGH 264
V F+ D L T S D+ +W+ G + E+ GH
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GH 296
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
++ H++ F+PD S +LV+ S D + ++W D + ++ R Q WV+ AF+
Sbjct: 165 NLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP 224
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
DS L + + LWN+++ T+ R+ GH + A F
Sbjct: 225 DSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDF 264
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/215 (22%), Positives = 84/215 (39%), Gaps = 20/215 (9%)
Query: 53 RVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-D 111
R F ++ + TG + +IWD + + + V + PD S I+V
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTG-KLLLNLVDHTEV-VRDLTFAPDGSLILVSAS 190
Query: 112 QSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ + +WDLK D N + + + A P M+ +V ++W++ +
Sbjct: 191 RDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMD---KYT 247
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR---------- 220
+ +K + H + C FSPD +L T S D IW + +L E
Sbjct: 248 MIRK-LEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFA 306
Query: 221 --DTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
RWV +F+ D + + + D R W I+
Sbjct: 307 GGANDRWVRSVSFSHDGLHVASLADDKMVRFWRID 341
>AK074435-1|BAB85083.1| 412|Homo sapiens protein ( Homo sapiens
cDNA FLJ23855 fis, clone LNG06370. ).
Length = 412
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 7/179 (3%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDL--KTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
V A+ D +++ G G + +W + +T + E+ + E ++S+ I + +
Sbjct: 212 VTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTA 271
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+ G C +W L + + I A++ + C + P+ ++T+ D W D
Sbjct: 272 STDGTCIIWDLVRLRRNQM----ILANTLFQCVC-YHPEEFQIITSGTDRKIAYWEVFDG 326
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++REL + T + TG +D ++W+ G + GH IT +
Sbjct: 327 TVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRI 385
Score = 39.5 bits (88), Expect = 0.013
Identities = 39/192 (20%), Positives = 69/192 (35%), Gaps = 10/192 (5%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
+++ G +R++ + ++ +VS + ++N T D T IWD
Sbjct: 224 VISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWD-- 281
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN-EQLIPEAEASI 137
R R ++ V HP++ QI+ I W++ +L SI
Sbjct: 282 -LVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSI 340
Query: 138 QDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCKFSPDSTMLV 196
+ I G N VW + G+ H HS R + SP + +V
Sbjct: 341 NGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVG-----VGHSGNITRIRISPGNQYIV 395
Query: 197 TTSGDCSAKIWR 208
+ S D + W+
Sbjct: 396 SVSADGAILRWK 407
>AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein.
Length = 421
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 6/163 (3%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNCYVW 161
DQ + G +G I IWD+ T + + + ++D+ P G + + + + VW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L K + H + C FSPDS+ML + + +W + ++R+L
Sbjct: 199 DLKDDGNM---MKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL-EG 254
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGH 264
V F+ D L T S D+ +W+ G + E+ GH
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GH 296
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
++ H++ F+PD S +LV+ S D + ++W D + ++ R Q WV+ AF+
Sbjct: 165 NLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP 224
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
DS L + + LWN+++ T+ R+ GH + A F
Sbjct: 225 DSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDF 264
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/215 (22%), Positives = 84/215 (39%), Gaps = 20/215 (9%)
Query: 53 RVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-D 111
R F ++ + TG + +IWD + + + V + PD S I+V
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTG-KLLLNLVDHTEV-VRDLTFAPDGSLILVSAS 190
Query: 112 QSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ + +WDLK D N + + + A P M+ +V ++W++ +
Sbjct: 191 RDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMD---KYT 247
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR---------- 220
+ +K + H + C FSPD +L T S D IW + +L E
Sbjct: 248 MIRK-LEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFA 306
Query: 221 --DTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
RWV +F+ D + + + D R W I+
Sbjct: 307 GGANDRWVRSVSFSHDGLHVASLADDKMVRFWRID 341
>AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein.
Length = 421
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 6/163 (3%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNCYVW 161
DQ + G +G I IWD+ T + + + ++D+ + P G + + + + VW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTLAPDGSLILVSASRDKTLRVW 198
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L K + H + C FSPDS+ML + +W + ++R+L
Sbjct: 199 DLKDDGNM---MKVLRGHQNWVYSCAFSPDSSMLCPVGASKAVFLWNMDKYTMIRKL-EG 254
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGH 264
V F+ D L T S D+ +W+ G + E+ GH
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GH 296
Score = 56.0 bits (129), Expect = 1e-07
Identities = 49/215 (22%), Positives = 84/215 (39%), Gaps = 20/215 (9%)
Query: 53 RVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-D 111
R F ++ + TG + +IWD + + + V + L PD S I+V
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTG-KLLLNLVDHTEV-VRDLTLAPDGSLILVSAS 190
Query: 112 QSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ + +WDLK D N + + + A P M+ V ++W++ +
Sbjct: 191 RDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCPVGASKAVFLWNMD---KYT 247
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR---------- 220
+ +K + H + C FSPD +L T S D IW + +L E
Sbjct: 248 MIRK-LEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFA 306
Query: 221 --DTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
RWV +F+ D + + + D R W I+
Sbjct: 307 GGANDRWVRSVSFSHDGLHVASLADDKMVRFWRID 341
Score = 53.2 bits (122), Expect = 1e-06
Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
++ H++ +PD S +LV+ S D + ++W D + ++ R Q WV+ AF+
Sbjct: 165 NLVDHTEVVRDLTLAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP 224
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
DS L + LWN+++ T+ R+ GH + A F
Sbjct: 225 DSSMLCPVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDF 264
>AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD
protein SWiP-1 protein.
Length = 421
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 6/163 (3%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNCYVW 161
DQ + G +G I IWD+ T + + + ++D+ P G + + + + VW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L K + H + C FSPDS+ML + + +W + ++R+L
Sbjct: 199 DLKDDGNM---MKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL-EG 254
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGH 264
V F+ D L T S D+ +W+ G + E+ GH
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GH 296
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
++ H++ F+PD S +LV+ S D + ++W D + ++ R Q WV+ AF+
Sbjct: 165 NLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP 224
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
DS L + + LWN+++ T+ R+ GH + A F
Sbjct: 225 DSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDF 264
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/215 (22%), Positives = 84/215 (39%), Gaps = 20/215 (9%)
Query: 53 RVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-D 111
R F ++ + TG + +IWD + + + V + PD S I+V
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTG-KLLLNLVDHTEV-VRDLTFAPDGSLILVSAS 190
Query: 112 QSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ + +WDLK D N + + + A P M+ +V ++W++ +
Sbjct: 191 RDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMD---KYT 247
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR---------- 220
+ +K + H + C FSPD +L T S D IW + +L E
Sbjct: 248 MIRK-LEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFA 306
Query: 221 --DTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
RWV +F+ D + + + D R W I+
Sbjct: 307 GGANDRWVRSVSFSHDGLHVASLADDKMVRFWRID 341
>AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein.
Length = 421
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 6/163 (3%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNCYVW 161
DQ + G +G I IWD+ T + + + ++D+ P G + + + + VW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L K + H + C FSPDS+ML + + +W + ++R+L
Sbjct: 199 DLKDDGNM---MKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL-EG 254
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGH 264
V F+ D L T S D+ +W+ G + E+ GH
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GH 296
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
++ H++ F+PD S +LV+ S D + ++W D + ++ R Q WV+ AF+
Sbjct: 165 NLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP 224
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
DS L + + LWN+++ T+ R+ GH + A F
Sbjct: 225 DSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDF 264
Score = 55.2 bits (127), Expect = 2e-07
Identities = 48/215 (22%), Positives = 84/215 (39%), Gaps = 20/215 (9%)
Query: 53 RVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-D 111
R F ++ + TG + +IWD + + + V + PD S I+V
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTG-KLLLNLVDHTEV-VRDLTFAPDGSLILVSAS 190
Query: 112 QSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ + +WDLK D N + + + A P M+ +V ++W++ +
Sbjct: 191 RDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMD---KYT 247
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRR---------- 220
+ +K + H + C FSPD +L T S D IW + +L E
Sbjct: 248 MIRK-LEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFA 306
Query: 221 --DTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
RWV +F+ D + + + D R W I+
Sbjct: 307 GGANDRWVRSVSFSHDGLHVASLADDKMVRFWRID 341
>AB065281-1|BAB83743.1| 620|Homo sapiens WDR16 protein.
Length = 620
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/179 (20%), Positives = 74/179 (41%), Gaps = 7/179 (3%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDL--KTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
V A+ D +++ G G + +W + +T + E+ + E ++S+ I + +
Sbjct: 420 VTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTA 479
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+ G C +W L + + I A++ + C + P+ ++T+ D W D
Sbjct: 480 STDGTCIIWDLVRLRRNQM----ILANTLFQCVC-YHPEEFQIITSGTDRKIAYWEVFDG 534
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++REL + T + TG +D ++W+ G + GH IT +
Sbjct: 535 TVIRELEGSLSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRI 593
Score = 39.5 bits (88), Expect = 0.013
Identities = 39/192 (20%), Positives = 69/192 (35%), Gaps = 10/192 (5%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
+++ G +R++ + ++ +VS + ++N T D T IWD
Sbjct: 432 VISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCIIWD-- 489
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN-EQLIPEAEASI 137
R R ++ V HP++ QI+ I W++ +L SI
Sbjct: 490 -LVRLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSI 548
Query: 138 QDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCKFSPDSTMLV 196
+ I G N VW + G+ H HS R + SP + +V
Sbjct: 549 NGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVG-----VGHSGNITRIRISPGNQYIV 603
Query: 197 TTSGDCSAKIWR 208
+ S D + W+
Sbjct: 604 SVSADGAILRWK 615
>BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like
1X-linked receptor 1 protein.
Length = 514
Score = 58.4 bits (135), Expect = 3e-08
Identities = 53/217 (24%), Positives = 89/217 (41%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 274 WNKKGNFILSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQSNNTFASCSTDM-C 330
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D+ + + I DP G ++A+ ++ +WS+ + + V
Sbjct: 331 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSM--KQDNCV--HD 386
Query: 176 ITAHSKYALRCKFSPD---------STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AH+K K+SP + ML + S D + ++W + L + Q V
Sbjct: 387 LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKH-QEPV 445
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D R+L +GS D +WN + G L Y G
Sbjct: 446 YSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482
Score = 56.8 bits (131), Expect = 8e-08
Identities = 56/234 (23%), Positives = 94/234 (40%), Gaps = 16/234 (6%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + GT + TG D ARIW + Q + P+ A+ + + I
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWTKDG---NLASTLGQHKGPIFALKWNKKGNFI 281
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQP 167
+ IWD T + +Q P A D+ + A+ + +V L GQ
Sbjct: 282 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCIHVCKL-GQD 339
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD-----T 222
P K H+ K+ P +L + S D + KIW + +L+ T
Sbjct: 340 R---PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYT 396
Query: 223 QRWVWDAAFTLDSR---FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + L + S DS RLW+++RG HQ+ + ++AF
Sbjct: 397 IKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 450
Score = 37.5 bits (83), Expect = 0.051
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD-------WALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S+ +LR R+ +
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + + L TGS D +AR+W + G L H+ I AL
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPIFAL 272
Score = 31.5 bits (68), Expect = 3.4
Identities = 19/130 (14%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
P+ TF+ + V+ + + G + + +D T +IW + + ++I+ ++ +
Sbjct: 341 PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400
Query: 94 PVNAVMLHPDQSQIMVGDQ-SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
P +P+ + ++ + +WD+ + + + + +A P G+ +A+
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460
Query: 153 NNKGNCYVWS 162
+ ++W+
Sbjct: 461 SFDKCVHIWN 470
>BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS
box-containing 2 protein.
Length = 404
Score = 58.4 bits (135), Expect = 3e-08
Identities = 38/153 (24%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Query: 102 PDQSQIMV--GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNC 158
PD S +++ G G I IW+++T + + ++D++ P+G + + + +
Sbjct: 119 PDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTL 178
Query: 159 YVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL 218
+W L+ H + ++ H ++ C SPD +ML + +G+ S +W + L+R+L
Sbjct: 179 RIWDLN---KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKL 235
Query: 219 RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
Q V F+ DS L T S D+ +W+
Sbjct: 236 -EGHQSSVVSCDFSPDSALLVTASYDTNVIMWD 267
Score = 47.2 bits (107), Expect = 6e-05
Identities = 48/205 (23%), Positives = 82/205 (40%), Gaps = 19/205 (9%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-DQSGIIHIWDL-K 122
TG D +IW+ + + Q V + P S I+V + + IWDL K
Sbjct: 128 TGLNDGQIKIWEVQTG--LLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 123 TDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKY 182
+ Q++ + +I P M+ + + + ++WS+ + + +K + H
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRS---YTLIRK-LEGHQSS 241
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD-----------AAF 231
+ C FSPDS +LVT S D + +W LR L D F
Sbjct: 242 VVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCF 301
Query: 232 TLDSRFLFTGSSDSYARLWNIERGT 256
+ + +L T + D R+W +E T
Sbjct: 302 SPEGLYLATVADDRLLRIWALELKT 326
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/100 (23%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
+++ H F+P S +LV+ S D + +IW + ++ +WV+ + +
Sbjct: 148 NLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISP 207
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D L + + + LW++ TL R+ GHQ ++ + F
Sbjct: 208 DCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDF 247
Score = 30.7 bits (66), Expect = 5.9
Identities = 12/36 (33%), Positives = 19/36 (52%)
Query: 238 LFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TG +D ++W ++ G L GHQ + L+F
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSF 161
>BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide binding
protein (G protein), beta 5 protein.
Length = 353
Score = 58.4 bits (135), Expect = 3e-08
Identities = 37/174 (21%), Positives = 69/174 (39%), Gaps = 3/174 (1%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA--VNNKGNCYV 160
D+ +I+ Q G + +WD T E + + A P+G +A ++NK + Y
Sbjct: 74 DKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYP 133
Query: 161 WSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR- 219
+ KK + H+ Y C F+ ++T SGD + +W LL+
Sbjct: 134 LTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHG 193
Query: 220 RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D A + +G D A +W++ G + + H+ I ++ +
Sbjct: 194 HGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247
Score = 44.0 bits (99), Expect = 6e-04
Identities = 31/153 (20%), Positives = 63/153 (41%), Gaps = 10/153 (6%)
Query: 58 KNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGII 116
+ G +GG D A +WD R+ +C + F+ ++ +N+V +P G
Sbjct: 207 ETGNTFVSGGCDKKAMVWDMRSG---QCVQAFETHESDINSVRYYPSGDAFASGSDDATC 263
Query: 117 HIWDLKTDQNEQLIPEAEASIQDIAID--PAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
++DL+ D+ + + ++D +G+++ A N VW + +
Sbjct: 264 RLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSI--- 320
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H + SPD T + S D + ++W
Sbjct: 321 -LFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 34.3 bits (75), Expect = 0.48
Identities = 33/170 (19%), Positives = 62/170 (36%), Gaps = 9/170 (5%)
Query: 106 QIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ--DIAIDPAGKMMAAVNNKGNCYVWSL 163
QI+ G +WD+++ Q Q A + D+A G + VW +
Sbjct: 167 QILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 226
Query: 164 -SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
SGQ H ++ P + S D + +++ +D + +
Sbjct: 227 RSGQCVQA-----FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKES 281
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
F+L R LF G +D +W++ +G+ GH+ ++ L
Sbjct: 282 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTL 331
Score = 34.3 bits (75), Expect = 0.48
Identities = 22/122 (18%), Positives = 46/122 (37%)
Query: 41 VTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVML 100
V FE +++ V + +G +G +D T R++D RA + ++V
Sbjct: 232 VQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDF 291
Query: 101 HPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
+ G I++WD+ ++ E + + + P G + + V
Sbjct: 292 SLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 351
Query: 161 WS 162
W+
Sbjct: 352 WA 353
>AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens
cDNA FLJ12894 fis, clone NT2RP2004170, moderately
similar to Homo sapiens mRNA for transducin (beta) like
1 protein. ).
Length = 514
Score = 58.4 bits (135), Expect = 3e-08
Identities = 53/217 (24%), Positives = 89/217 (41%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 274 WNKKGNFILSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQSNNTFASCSTDM-C 330
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D+ + + I DP G ++A+ ++ +WS+ + + V
Sbjct: 331 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSM--KQDNCV--HD 386
Query: 176 ITAHSKYALRCKFSPD---------STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AH+K K+SP + ML + S D + ++W + L + Q V
Sbjct: 387 LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKH-QEPV 445
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D R+L +GS D +WN + G L Y G
Sbjct: 446 YSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482
Score = 56.8 bits (131), Expect = 8e-08
Identities = 56/234 (23%), Positives = 94/234 (40%), Gaps = 16/234 (6%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + GT + TG D ARIW + Q + P+ A+ + + I
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWTKDG---NLASTLGQHKGPIFALKWNKKGNFI 281
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQP 167
+ IWD T + +Q P A D+ + A+ + +V L GQ
Sbjct: 282 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCIHVCKL-GQD 339
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD-----T 222
P K H+ K+ P +L + S D + KIW + +L+ T
Sbjct: 340 R---PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYT 396
Query: 223 QRWVWDAAFTLDSR---FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + L + S DS RLW+++RG HQ+ + ++AF
Sbjct: 397 IKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 450
Score = 37.5 bits (83), Expect = 0.051
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD-------WALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S+ +LR R+ +
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + + L TGS D +AR+W + G L H+ I AL
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPIFAL 272
Score = 31.5 bits (68), Expect = 3.4
Identities = 19/130 (14%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
P+ TF+ + V+ + + G + + +D T +IW + + ++I+ ++ +
Sbjct: 341 PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400
Query: 94 PVNAVMLHPDQSQIMVGDQ-SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
P +P+ + ++ + +WD+ + + + + +A P G+ +A+
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460
Query: 153 NNKGNCYVWS 162
+ ++W+
Sbjct: 461 SFDKCVHIWN 470
>AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide binding
protein beta 5 protein.
Length = 353
Score = 58.4 bits (135), Expect = 3e-08
Identities = 37/174 (21%), Positives = 69/174 (39%), Gaps = 3/174 (1%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA--VNNKGNCYV 160
D+ +I+ Q G + +WD T E + + A P+G +A ++NK + Y
Sbjct: 74 DKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYP 133
Query: 161 WSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR- 219
+ KK + H+ Y C F+ ++T SGD + +W LL+
Sbjct: 134 LTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHG 193
Query: 220 RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D A + +G D A +W++ G + + H+ I ++ +
Sbjct: 194 HGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247
Score = 44.0 bits (99), Expect = 6e-04
Identities = 31/153 (20%), Positives = 63/153 (41%), Gaps = 10/153 (6%)
Query: 58 KNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGII 116
+ G +GG D A +WD R+ +C + F+ ++ +N+V +P G
Sbjct: 207 ETGNTFVSGGCDKKAMVWDMRSG---QCVQAFETHESDINSVRYYPSGDAFASGSDDATC 263
Query: 117 HIWDLKTDQNEQLIPEAEASIQDIAID--PAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
++DL+ D+ + + ++D +G+++ A N VW + +
Sbjct: 264 RLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSI--- 320
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H + SPD T + S D + ++W
Sbjct: 321 -LFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 34.3 bits (75), Expect = 0.48
Identities = 33/170 (19%), Positives = 62/170 (36%), Gaps = 9/170 (5%)
Query: 106 QIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ--DIAIDPAGKMMAAVNNKGNCYVWSL 163
QI+ G +WD+++ Q Q A + D+A G + VW +
Sbjct: 167 QILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 226
Query: 164 -SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
SGQ H ++ P + S D + +++ +D + +
Sbjct: 227 RSGQCVQA-----FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKES 281
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
F+L R LF G +D +W++ +G+ GH+ ++ L
Sbjct: 282 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTL 331
Score = 34.3 bits (75), Expect = 0.48
Identities = 22/122 (18%), Positives = 46/122 (37%)
Query: 41 VTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVML 100
V FE +++ V + +G +G +D T R++D RA + ++V
Sbjct: 232 VQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDF 291
Query: 101 HPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
+ G I++WD+ ++ E + + + P G + + V
Sbjct: 292 SLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 351
Query: 161 WS 162
W+
Sbjct: 352 WA 353
>AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor
co-repressor/HDAC3 complex subunit TBLR1 protein.
Length = 514
Score = 58.4 bits (135), Expect = 3e-08
Identities = 53/217 (24%), Positives = 89/217 (41%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 274 WNKKGNFILSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQSNNTFASCSTDM-C 330
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D+ + + I DP G ++A+ ++ +WS+ + + V
Sbjct: 331 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSM--KQDNCV--HD 386
Query: 176 ITAHSKYALRCKFSPD---------STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ AH+K K+SP + ML + S D + ++W + L + Q V
Sbjct: 387 LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKH-QEPV 445
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D R+L +GS D +WN + G L Y G
Sbjct: 446 YSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482
Score = 56.8 bits (131), Expect = 8e-08
Identities = 56/234 (23%), Positives = 94/234 (40%), Gaps = 16/234 (6%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + GT + TG D ARIW + Q + P+ A+ + + I
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWTKDG---NLASTLGQHKGPIFALKWNKKGNFI 281
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQP 167
+ IWD T + +Q P A D+ + A+ + +V L GQ
Sbjct: 282 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCIHVCKL-GQD 339
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD-----T 222
P K H+ K+ P +L + S D + KIW + +L+ T
Sbjct: 340 R---PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYT 396
Query: 223 QRWVWDAAFTLDSR---FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + L + S DS RLW+++RG HQ+ + ++AF
Sbjct: 397 IKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 450
Score = 37.5 bits (83), Expect = 0.051
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD-------WALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S+ +LR R+ +
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + + L TGS D +AR+W + G L H+ I AL
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPIFAL 272
Score = 31.5 bits (68), Expect = 3.4
Identities = 19/130 (14%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
P+ TF+ + V+ + + G + + +D T +IW + + ++I+ ++ +
Sbjct: 341 PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400
Query: 94 PVNAVMLHPDQSQIMVGDQ-SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
P +P+ + ++ + +WD+ + + + + +A P G+ +A+
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460
Query: 153 NNKGNCYVWS 162
+ ++W+
Sbjct: 461 SFDKCVHIWN 470
>AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide binding
protein beta subunit 5L protein.
Length = 395
Score = 58.4 bits (135), Expect = 3e-08
Identities = 37/174 (21%), Positives = 69/174 (39%), Gaps = 3/174 (1%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA--VNNKGNCYV 160
D+ +I+ Q G + +WD T E + + A P+G +A ++NK + Y
Sbjct: 116 DKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYP 175
Query: 161 WSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR- 219
+ KK + H+ Y C F+ ++T SGD + +W LL+
Sbjct: 176 LTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHG 235
Query: 220 RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D A + +G D A +W++ G + + H+ I ++ +
Sbjct: 236 HGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 289
Score = 44.0 bits (99), Expect = 6e-04
Identities = 31/153 (20%), Positives = 63/153 (41%), Gaps = 10/153 (6%)
Query: 58 KNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGII 116
+ G +GG D A +WD R+ +C + F+ ++ +N+V +P G
Sbjct: 249 ETGNTFVSGGCDKKAMVWDMRSG---QCVQAFETHESDINSVRYYPSGDAFASGSDDATC 305
Query: 117 HIWDLKTDQNEQLIPEAEASIQDIAID--PAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
++DL+ D+ + + ++D +G+++ A N VW + +
Sbjct: 306 RLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSI--- 362
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H + SPD T + S D + ++W
Sbjct: 363 -LFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 394
Score = 34.3 bits (75), Expect = 0.48
Identities = 33/170 (19%), Positives = 62/170 (36%), Gaps = 9/170 (5%)
Query: 106 QIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ--DIAIDPAGKMMAAVNNKGNCYVWSL 163
QI+ G +WD+++ Q Q A + D+A G + VW +
Sbjct: 209 QILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 268
Query: 164 -SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
SGQ H ++ P + S D + +++ +D + +
Sbjct: 269 RSGQCVQA-----FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKES 323
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
F+L R LF G +D +W++ +G+ GH+ ++ L
Sbjct: 324 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTL 373
Score = 34.3 bits (75), Expect = 0.48
Identities = 22/122 (18%), Positives = 46/122 (37%)
Query: 41 VTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVML 100
V FE +++ V + +G +G +D T R++D RA + ++V
Sbjct: 274 VQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDF 333
Query: 101 HPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
+ G I++WD+ ++ E + + + P G + + V
Sbjct: 334 SLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 393
Query: 161 WS 162
W+
Sbjct: 394 WA 395
>AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD
protein protein.
Length = 404
Score = 58.4 bits (135), Expect = 3e-08
Identities = 38/153 (24%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Query: 102 PDQSQIMV--GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNC 158
PD S +++ G G I IW+++T + + ++D++ P+G + + + +
Sbjct: 119 PDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTL 178
Query: 159 YVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL 218
+W L+ H + ++ H ++ C SPD +ML + +G+ S +W + L+R+L
Sbjct: 179 RIWDLN---KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKL 235
Query: 219 RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
Q V F+ DS L T S D+ +W+
Sbjct: 236 -EGHQSSVVSCDFSPDSALLVTASYDTNVIMWD 267
Score = 47.2 bits (107), Expect = 6e-05
Identities = 48/205 (23%), Positives = 82/205 (40%), Gaps = 19/205 (9%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-DQSGIIHIWDL-K 122
TG D +IW+ + + Q V + P S I+V + + IWDL K
Sbjct: 128 TGLNDGQIKIWEVQTG--LLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 123 TDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKY 182
+ Q++ + +I P M+ + + + ++WS+ + + +K + H
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRS---YTLIRK-LEGHQSS 241
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD-----------AAF 231
+ C FSPDS +LVT S D + +W LR L D F
Sbjct: 242 VVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCF 301
Query: 232 TLDSRFLFTGSSDSYARLWNIERGT 256
+ + +L T + D R+W +E T
Sbjct: 302 SPEGLYLATVADDRLLRIWALELKT 326
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/100 (23%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
+++ H F+P S +LV+ S D + +IW + ++ +WV+ + +
Sbjct: 148 NLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISP 207
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D L + + + LW++ TL R+ GHQ ++ + F
Sbjct: 208 DCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDF 247
Score = 30.7 bits (66), Expect = 5.9
Identities = 12/36 (33%), Positives = 19/36 (52%)
Query: 238 LFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TG +D ++W ++ G L GHQ + L+F
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSF 161
>AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein.
Length = 404
Score = 58.4 bits (135), Expect = 3e-08
Identities = 38/153 (24%), Positives = 74/153 (48%), Gaps = 7/153 (4%)
Query: 102 PDQSQIMV--GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM-MAAVNNKGNC 158
PD S +++ G G I IW+++T + + ++D++ P+G + + + +
Sbjct: 119 PDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTL 178
Query: 159 YVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL 218
+W L+ H + ++ H ++ C SPD +ML + +G+ S +W + L+R+L
Sbjct: 179 RIWDLN---KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKL 235
Query: 219 RRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
Q V F+ DS L T S D+ +W+
Sbjct: 236 -EGHQSSVVSCDFSPDSALLVTASYDTNVIMWD 267
Score = 47.2 bits (107), Expect = 6e-05
Identities = 48/205 (23%), Positives = 82/205 (40%), Gaps = 19/205 (9%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG-DQSGIIHIWDL-K 122
TG D +IW+ + + Q V + P S I+V + + IWDL K
Sbjct: 128 TGLNDGQIKIWEVQTG--LLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNK 185
Query: 123 TDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKY 182
+ Q++ + +I P M+ + + + ++WS+ + + +K + H
Sbjct: 186 HGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRS---YTLIRK-LEGHQSS 241
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD-----------AAF 231
+ C FSPDS +LVT S D + +W LR L D F
Sbjct: 242 VVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCF 301
Query: 232 TLDSRFLFTGSSDSYARLWNIERGT 256
+ + +L T + D R+W +E T
Sbjct: 302 SPEGLYLATVADDRLLRIWALELKT 326
Score = 41.1 bits (92), Expect = 0.004
Identities = 23/100 (23%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
+++ H F+P S +LV+ S D + +IW + ++ +WV+ + +
Sbjct: 148 NLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISP 207
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D L + + + LW++ TL R+ GHQ ++ + F
Sbjct: 208 DCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDF 247
Score = 30.7 bits (66), Expect = 5.9
Identities = 12/36 (33%), Positives = 19/36 (52%)
Query: 238 LFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TG +D ++W ++ G L GHQ + L+F
Sbjct: 126 LATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSF 161
>AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subunit
protein.
Length = 353
Score = 58.4 bits (135), Expect = 3e-08
Identities = 37/174 (21%), Positives = 69/174 (39%), Gaps = 3/174 (1%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA--VNNKGNCYV 160
D+ +I+ Q G + +WD T E + + A P+G +A ++NK + Y
Sbjct: 74 DKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAYAPSGCAIACGGLDNKCSVYP 133
Query: 161 WSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR- 219
+ KK + H+ Y C F+ ++T SGD + +W LL+
Sbjct: 134 LTFDKNENMAAKKKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHG 193
Query: 220 RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D A + +G D A +W++ G + + H+ I ++ +
Sbjct: 194 HGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRY 247
Score = 44.0 bits (99), Expect = 6e-04
Identities = 31/153 (20%), Positives = 63/153 (41%), Gaps = 10/153 (6%)
Query: 58 KNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGII 116
+ G +GG D A +WD R+ +C + F+ ++ +N+V +P G
Sbjct: 207 ETGNTFVSGGCDKKAMVWDMRSG---QCVQAFETHESDINSVRYYPSGDAFASGSDDATC 263
Query: 117 HIWDLKTDQNEQLIPEAEASIQDIAID--PAGKMMAAVNNKGNCYVWSLSGQPPHPVPKK 174
++DL+ D+ + + ++D +G+++ A N VW + +
Sbjct: 264 RLYDLRADREVAIYSKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSI--- 320
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ H + SPD T + S D + ++W
Sbjct: 321 -LFGHENRVSTLRVSPDGTAFCSGSWDHTLRVW 352
Score = 34.3 bits (75), Expect = 0.48
Identities = 33/170 (19%), Positives = 62/170 (36%), Gaps = 9/170 (5%)
Query: 106 QIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ--DIAIDPAGKMMAAVNNKGNCYVWSL 163
QI+ G +WD+++ Q Q A + D+A G + VW +
Sbjct: 167 QILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDM 226
Query: 164 -SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
SGQ H ++ P + S D + +++ +D + +
Sbjct: 227 RSGQCVQA-----FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKES 281
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
F+L R LF G +D +W++ +G+ GH+ ++ L
Sbjct: 282 IIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTL 331
Score = 34.3 bits (75), Expect = 0.48
Identities = 22/122 (18%), Positives = 46/122 (37%)
Query: 41 VTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVML 100
V FE +++ V + +G +G +D T R++D RA + ++V
Sbjct: 232 VQAFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDF 291
Query: 101 HPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
+ G I++WD+ ++ E + + + P G + + V
Sbjct: 292 SLSGRLLFAGYNDYTINVWDVLKGSRVSILFGHENRVSTLRVSPDGTAFCSGSWDHTLRV 351
Query: 161 WS 162
W+
Sbjct: 352 WA 353
>X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer complex
protein.
Length = 906
Score = 58.0 bits (134), Expect = 3e-08
Identities = 55/255 (21%), Positives = 96/255 (37%), Gaps = 9/255 (3%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
++V S+++ PT A + + + V TFE V F W+ TG
Sbjct: 16 DRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTG 75
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDL-KTD 124
+D R+++ R +F+ + + + +HP Q I+ +I +WD K
Sbjct: 76 ADDMQIRVFNYNTLERVH---MFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKW 132
Query: 125 QNEQLIPEAEASIQDIAIDPA-GKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q+ + I I+P A+ + VW L P+ + H
Sbjct: 133 SCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGH--EKGVNC 190
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D L++ + D KIW + ++ L Q V A+F + + TGS
Sbjct: 191 IDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQN-VSCASFHPELPIIITGSE 249
Query: 244 DSYARLWNIERGTLE 258
D R+W+ LE
Sbjct: 250 DGTVRIWHSSTYRLE 264
Score = 40.3 bits (90), Expect = 0.007
Identities = 42/214 (19%), Positives = 85/214 (39%), Gaps = 9/214 (4%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
+V A IR+++ ++ + V FE S + + ++ T +D ++WD
Sbjct: 72 VVTGADDMQIRVFNYNTL--ERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWD-- 127
Query: 79 AAPRTRCQKIFQVQAP-VNAVMLHP-DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEAS 136
+ C ++F+ V ++++P D +Q I +W L + + E
Sbjct: 128 WDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKG 187
Query: 137 IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLV 196
+ I G ++ + V Q V + + H++ F P+ +++
Sbjct: 188 VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCV--QTLEGHAQNVSCASFHPELPIII 245
Query: 197 TTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAA 230
T S D + +IW +S + L L +R VW A
Sbjct: 246 TGSEDGTVRIWHSSTYRLESTLNYGMER-VWCVA 278
Score = 33.5 bits (73), Expect = 0.83
Identities = 40/230 (17%), Positives = 85/230 (36%), Gaps = 11/230 (4%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQ 106
S V V WM + + +W+ K F+V PV A ++
Sbjct: 15 SDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLV---KTFEVCDLPVRAAKFVARKNW 71
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G I +++ T + + I+ IA+ P + ++ +W +
Sbjct: 72 VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKK 131
Query: 167 PPHPVPKKHITAHSKYALRCKFSP-DSTMLVTTSGDCSAKIWR--TSDWALLRELRRDTQ 223
+ H+ Y ++ +P D+ + S D + K+W+ +S E
Sbjct: 132 WSC---SQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGV 188
Query: 224 RWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D D +L +G+ D ++W+ + T + GH + ++ +F
Sbjct: 189 NCI-DYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASF 237
>BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein complex,
subunit beta 2 (beta prime) protein.
Length = 906
Score = 58.0 bits (134), Expect = 3e-08
Identities = 55/255 (21%), Positives = 96/255 (37%), Gaps = 9/255 (3%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
++V S+++ PT A + + + V TFE V F W+ TG
Sbjct: 16 DRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTG 75
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDL-KTD 124
+D R+++ R +F+ + + + +HP Q I+ +I +WD K
Sbjct: 76 ADDMQIRVFNYNTLERVH---MFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKW 132
Query: 125 QNEQLIPEAEASIQDIAIDPA-GKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYA 183
Q+ + I I+P A+ + VW L P+ + H
Sbjct: 133 SCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGH--EKGVNC 190
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSS 243
+ D L++ + D KIW + ++ L Q V A+F + + TGS
Sbjct: 191 IDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQN-VSCASFHPELPIIITGSE 249
Query: 244 DSYARLWNIERGTLE 258
D R+W+ LE
Sbjct: 250 DGTVRIWHSSTYRLE 264
Score = 40.3 bits (90), Expect = 0.007
Identities = 42/214 (19%), Positives = 85/214 (39%), Gaps = 9/214 (4%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
+V A IR+++ ++ + V FE S + + ++ T +D ++WD
Sbjct: 72 VVTGADDMQIRVFNYNTL--ERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWD-- 127
Query: 79 AAPRTRCQKIFQVQAP-VNAVMLHP-DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEAS 136
+ C ++F+ V ++++P D +Q I +W L + + E
Sbjct: 128 WDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKG 187
Query: 137 IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLV 196
+ I G ++ + V Q V + + H++ F P+ +++
Sbjct: 188 VNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCV--QTLEGHAQNVSCASFHPELPIII 245
Query: 197 TTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAA 230
T S D + +IW +S + L L +R VW A
Sbjct: 246 TGSEDGTVRIWHSSTYRLESTLNYGMER-VWCVA 278
Score = 33.5 bits (73), Expect = 0.83
Identities = 40/230 (17%), Positives = 85/230 (36%), Gaps = 11/230 (4%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQ 106
S V V WM + + +W+ K F+V PV A ++
Sbjct: 15 SDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLV---KTFEVCDLPVRAAKFVARKNW 71
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G I +++ T + + I+ IA+ P + ++ +W +
Sbjct: 72 VVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKK 131
Query: 167 PPHPVPKKHITAHSKYALRCKFSP-DSTMLVTTSGDCSAKIWR--TSDWALLRELRRDTQ 223
+ H+ Y ++ +P D+ + S D + K+W+ +S E
Sbjct: 132 WSC---SQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGV 188
Query: 224 RWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D D +L +G+ D ++W+ + T + GH + ++ +F
Sbjct: 189 NCI-DYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASF 237
>AK093494-1|BAC04184.1| 476|Homo sapiens protein ( Homo sapiens
cDNA FLJ36175 fis, clone TESTI2026453, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC
2.7.1.-). ).
Length = 476
Score = 58.0 bits (134), Expect = 3e-08
Identities = 60/237 (25%), Positives = 101/237 (42%), Gaps = 16/237 (6%)
Query: 34 SSANPDPVTTFEDISKNVSRV-GFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ 92
++ N + E S + RV F + T + +G D T +W+ ++ RC +
Sbjct: 82 NTENGQMLAVMEQPSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSV--KD 139
Query: 93 APVNAVMLHPDQSQIMVGDQSGIIHIWD-----LKTDQNEQL-IPEAEASIQDIAIDPAG 146
+ A P+ S + G G + +WD L +++ L I + S Q ++ G
Sbjct: 140 GSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQPVSDGEQG 199
Query: 147 KMMAAVNNKG-NCYV--WSLSGQPPHPVPKKH---ITAHSKYALRCKFSPDSTMLVTTSG 200
+ + G +C V W +S K+ ++ H L C FS D MLV+ S
Sbjct: 200 LQFFRLASCGQDCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLACAFSHDGQMLVSGSV 259
Query: 201 DCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
D S ++ T+ +L L + T R+V AF ++ L TGS D +W + TL
Sbjct: 260 DKSVIVYDTNTENILHTLTQHT-RYVTTCAFAPNTLLLATGSMDKTVNIWQFDLETL 315
Score = 44.0 bits (99), Expect = 6e-04
Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 4/105 (3%)
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAA 230
+P + H+ C FSP +L + S D + +W T + +L + + + V
Sbjct: 45 LPHSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVRVCQ 104
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQK--AITALAF 273
F+ DS L +G++D LWN + L R CG K ++ A AF
Sbjct: 105 FSPDSTCLASGAADGTVVLWNAQSYKLYR--CGSVKDGSLAACAF 147
Score = 39.5 bits (88), Expect = 0.013
Identities = 55/278 (19%), Positives = 101/278 (36%), Gaps = 12/278 (4%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+ VN S + + + + IRLY L P + + + V F +G + +
Sbjct: 13 DDVNCCAFSFSLLATCSLDKTIRLYSLRDFTELPHSPLKFHTYAVHCCCFSPSGHILASC 72
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
D T +W+ + +PV PD + + G G + +W+ ++ +
Sbjct: 73 STDGTTVLWNTENGQMLAVMEQ-PSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKL 131
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-----LSGQPPHPVPKKHITAHSK 181
+ + S+ A P G ++ G+ VW L + H + S+
Sbjct: 132 YRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQ 191
Query: 182 YALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLR-ELR-RDTQRW----VWDAAFTLDS 235
+ L + DC KIW S +L EL+ + T V AF+ D
Sbjct: 192 PVSDGEQGLQFFRLASCGQDCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLACAFSHDG 251
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ L +GS D +++ + H + +T AF
Sbjct: 252 QMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAF 289
>AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 997 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1055
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1056 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1109
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1110 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1161
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/239 (22%), Positives = 85/239 (35%), Gaps = 28/239 (11%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI---------------TAHSKYALRCKFSPDSTML 195
V C WS G K I T H C FSP + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLA 855
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V ++W T + + + R WV F+ D T S D RLW ++
Sbjct: 856 VVALSQYCVELWNTDSRSKVADCRGHLS-WVHGVMFSPDGSSFLTSSDDQTIRLWETKK 913
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 885 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 940
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 941 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 994
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 995 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1050
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1051 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1088
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 963 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 1022
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 1023 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1078
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1079 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1133
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1134 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1193
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1194 --SAGGYIKWWNVVTG 1207
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating factor-1
protein.
Length = 1205
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 954 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1012
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1013 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1066
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1067 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 842 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 897
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 898 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 951
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 952 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1007
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1008 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1045
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 920 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 979
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 980 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1035
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1036 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1090
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1151 --SAGGYIKWWNVVTG 1164
Score = 42.7 bits (96), Expect = 0.001
Identities = 24/98 (24%), Positives = 41/98 (41%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ R FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 34.3 bits (75), Expect = 0.48
Identities = 30/162 (18%), Positives = 63/162 (38%), Gaps = 14/162 (8%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQI 107
V R F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 618 VYRACFSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFI 672
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSG 165
+ IW+ T + E + + + +C++ W L+
Sbjct: 673 ATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQ 732
Query: 166 QPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + + H+ C+FSPD +L + S D + K+W
Sbjct: 733 KEC----RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 954 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1012
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1013 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1066
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1067 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 842 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 897
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 898 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 951
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 952 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1007
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1008 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1045
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH + F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSANHCRF 751
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 920 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 979
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 980 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1035
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1036 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1090
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1151 --SAGGYIKWWNVVTG 1164
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 37.9 bits (84), Expect = 0.039
Identities = 43/193 (22%), Positives = 71/193 (36%), Gaps = 26/193 (13%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
N PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 HTNSANHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI--------------TAHSKYALRCKFSPDSTMLV 196
V C WS G K I H + FSPD + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL 855
Query: 197 TTSGDCSAKIWRT 209
T+S D + ++W T
Sbjct: 856 TSSDDQTIRLWET 868
Score = 34.3 bits (75), Expect = 0.48
Identities = 29/157 (18%), Positives = 62/157 (39%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ A C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSANHCRFSPDDKLLASCSADGTLKLW 770
>AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 997 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1055
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1056 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1109
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1110 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1161
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/239 (22%), Positives = 85/239 (35%), Gaps = 28/239 (11%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI---------------TAHSKYALRCKFSPDSTML 195
V C WS G K I T H C FSP + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLFAIHTSGLLGEIHTGHHSTIQYCDFSPQNHLA 855
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V ++W T + + + R WV F+ D T S D RLW ++
Sbjct: 856 VVALSQYCVELWNTDSRSKVADCRGHLS-WVHGVMFSPDGSSFLTSSDDQTIRLWETKK 913
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 885 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 940
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 941 DHIRRLQLVNGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 994
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 995 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1050
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1051 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1088
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 963 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 1022
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 1023 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1078
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1079 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1133
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1134 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1193
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1194 --SAGGYIKWWNVVTG 1207
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 954 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1012
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1013 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1066
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1067 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 842 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 897
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 898 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 951
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 952 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1007
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1008 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1045
Score = 44.8 bits (101), Expect = 3e-04
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + G ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGRTNSVNHCRF 751
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 920 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 979
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 980 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1035
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1036 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1090
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1151 --SAGGYIKWWNVVTG 1164
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 39.5 bits (88), Expect = 0.013
Identities = 44/193 (22%), Positives = 72/193 (37%), Gaps = 26/193 (13%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 RTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI--------------TAHSKYALRCKFSPDSTMLV 196
V C WS G K I H + FSPD + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL 855
Query: 197 TTSGDCSAKIWRT 209
T+S D + ++W T
Sbjct: 856 TSSDDQTIRLWET 868
>AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 954 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1012
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1013 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1066
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1067 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 842 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 897
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 898 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 951
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 952 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1007
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1008 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1045
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 920 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 979
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 980 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1035
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1036 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1090
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1151 --SAGGYIKWWNVVTG 1164
Score = 40.3 bits (90), Expect = 0.007
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTFQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 39.5 bits (88), Expect = 0.013
Identities = 44/193 (22%), Positives = 72/193 (37%), Gaps = 26/193 (13%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI--------------TAHSKYALRCKFSPDSTMLV 196
V C WS G K I H + FSPD + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL 855
Query: 197 TTSGDCSAKIWRT 209
T+S D + ++W T
Sbjct: 856 TSSDDQTIRLWET 868
Score = 32.3 bits (70), Expect = 1.9
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTFQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 954 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1012
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1013 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1066
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1067 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 842 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 897
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 898 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 951
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 952 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1007
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1008 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1045
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 920 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 979
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 980 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1035
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1036 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1090
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1151 --SAGGYIKWWNVVTG 1164
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 954 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1012
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1013 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1066
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1067 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 842 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 897
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 898 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 951
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 952 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1007
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1008 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1045
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 920 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 979
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 980 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1035
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1036 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1090
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1151 --SAGGYIKWWNVVTG 1164
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 39.5 bits (88), Expect = 0.013
Identities = 44/193 (22%), Positives = 72/193 (37%), Gaps = 26/193 (13%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI--------------TAHSKYALRCKFSPDSTMLV 196
V C WS G K I H + FSPD + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL 855
Query: 197 TTSGDCSAKIWRT 209
T+S D + ++W T
Sbjct: 856 TSSDDQTIRLWET 868
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 954 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1012
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1013 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1066
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1067 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 842 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 897
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 898 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 951
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 952 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1007
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1008 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1045
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V F S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFANSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 920 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 979
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 980 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1035
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1036 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1090
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1151 --SAGGYIKWWNVVTG 1164
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 39.5 bits (88), Expect = 0.013
Identities = 44/193 (22%), Positives = 72/193 (37%), Gaps = 26/193 (13%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI--------------TAHSKYALRCKFSPDSTMLV 196
V C WS G K I H + FSPD + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL 855
Query: 197 TTSGDCSAKIWRT 209
T+S D + ++W T
Sbjct: 856 TSSDDQTIRLWET 868
Score = 32.3 bits (70), Expect = 1.9
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFANSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1248
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 997 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1055
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1056 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1109
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1110 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1161
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/239 (22%), Positives = 85/239 (35%), Gaps = 28/239 (11%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI---------------TAHSKYALRCKFSPDSTML 195
V C WS G K I T H C FSP + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLA 855
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V ++W T + + + R WV F+ D T S D RLW ++
Sbjct: 856 VVALSQYCVELWNTDSRSKVADCRGHLS-WVHGVMFSPDGSSFLTSSDDQTIRLWETKK 913
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 885 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 940
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 941 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 994
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 995 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1050
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1051 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1088
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 963 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 1022
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 1023 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1078
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1079 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1133
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1134 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1193
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1194 --SAGGYIKWWNVVTG 1207
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease
activating factor-1 long isoform APAF-1L protein.
Length = 1237
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 986 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1044
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1045 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1098
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1099 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1150
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/239 (22%), Positives = 85/239 (35%), Gaps = 28/239 (11%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 674 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 730
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 731 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 788
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI---------------TAHSKYALRCKFSPDSTML 195
V C WS G K I T H C FSP + +
Sbjct: 789 IVK----CCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLA 844
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V ++W T + + + R WV F+ D T S D RLW ++
Sbjct: 845 VVALSQYCVELWNTDSRSKVADCRGHLS-WVHGVMFSPDGSSFLTSSDDQTIRLWETKK 902
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 642 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 700
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 701 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 740
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 874 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 929
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 930 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 983
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 984 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1039
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1040 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1077
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 952 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 1011
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 1012 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1067
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1068 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1122
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1123 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1182
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1183 --SAGGYIKWWNVVTG 1196
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 658
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 659 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 696
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 612 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 666
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 667 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 724
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 725 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 759
>AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1194
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 943 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1001
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1002 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1055
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1056 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1107
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 642 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 700
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 701 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 740
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 831 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 886
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 887 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 940
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 941 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 996
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 997 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1034
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 909 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 968
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 969 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1024
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1025 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1079
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1080 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1139
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1140 --SAGGYIKWWNVVTG 1153
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 658
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 659 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 696
Score = 39.5 bits (88), Expect = 0.013
Identities = 44/193 (22%), Positives = 72/193 (37%), Gaps = 26/193 (13%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 674 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 730
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 731 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 788
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI--------------TAHSKYALRCKFSPDSTMLV 196
V C WS G K I H + FSPD + +
Sbjct: 789 IVK----CCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL 844
Query: 197 TTSGDCSAKIWRT 209
T+S D + ++W T
Sbjct: 845 TSSDDQTIRLWET 857
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 612 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 666
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 667 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 724
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 725 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 759
>AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein.
Length = 1237
Score = 58.0 bits (134), Expect = 3e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 986 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1044
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1045 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1098
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1099 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1150
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/239 (22%), Positives = 85/239 (35%), Gaps = 28/239 (11%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 674 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 730
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 731 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 788
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI---------------TAHSKYALRCKFSPDSTML 195
V C WS G K I T H C FSP + +
Sbjct: 789 IVK----CCSWSADGARIMVAAKNKIFLFDIHTSGLLGEIHTGHHSTIQYCDFSPQNHLA 844
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
V ++W T + + + R WV F+ D T S D RLW ++
Sbjct: 845 VVALSQYCVELWNTDSRSKVADCRGHLS-WVHGVMFSPDGSSFLTSSDDQTIRLWETKK 902
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 642 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 700
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 701 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 740
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 874 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 929
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 930 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 983
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 984 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1039
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1040 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1077
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V + F + + +
Sbjct: 952 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLISSS 1011
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + S+++ G + +W++ T E
Sbjct: 1012 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKN-SRLLSWSFDGTVKVWNIITGNKE 1067
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1068 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1122
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1123 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1182
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1183 --SAGGYIKWWNVVTG 1196
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 600 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 658
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 659 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 696
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 612 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 666
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 667 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 724
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 725 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 759
>BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein.
Length = 441
Score = 57.6 bits (133), Expect = 4e-08
Identities = 39/179 (21%), Positives = 67/179 (37%), Gaps = 5/179 (2%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V V + Q+ G + +W +K + ++ + P+G ++A+ +
Sbjct: 56 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 115
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWAL 214
+W + + V AH+ F D VT S D + K+W T
Sbjct: 116 DKTVRIWVPNVKGESTV----FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKF 171
Query: 215 LRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L L + WV A F+ D R + + S D +LW+ YC H +T + F
Sbjct: 172 LFSLSQHIN-WVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 229
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 9/224 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMV 109
V+ V F +G + +G D T RIW P + +F+ A V +V D +
Sbjct: 98 VTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST---VFRAHTATVRSVHFCSDGQSFVT 154
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPH 169
+ +W + + + ++ P G+++ + ++ +W S +
Sbjct: 155 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSREC- 213
Query: 170 PVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA 229
H + F P T + D + K+W LL+ + + V
Sbjct: 214 ---VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAA-VNGL 269
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+F +L T SSDS ++ ++ G L GHQ T +AF
Sbjct: 270 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAF 313
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/248 (22%), Positives = 89/248 (35%), Gaps = 15/248 (6%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+ V + SP+ + A+G + + T F + V V F +G T
Sbjct: 96 DAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTA 155
Query: 67 GEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAV---MLHPDQSQIMVGDQSGIIHIWDLK 122
+D T ++W T QK +F + +N V PD I+ + +WD
Sbjct: 156 SDDKTVKVW------ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS 209
Query: 123 TDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKY 182
+ + E + + P+G +AA VW + H + +H HS
Sbjct: 210 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR---THRL-LQHYQLHSAA 265
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
F P L+T S D + KI + LL L Q AF+ + +G
Sbjct: 266 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL-HGHQGPATTVAFSRTGEYFASGG 324
Query: 243 SDSYARLW 250
SD +W
Sbjct: 325 SDEQVMVW 332
>BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A
protein.
Length = 407
Score = 57.6 bits (133), Expect = 4e-08
Identities = 39/179 (21%), Positives = 67/179 (37%), Gaps = 5/179 (2%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V V + Q+ G + +W +K + ++ + P+G ++A+ +
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWAL 214
+W + + V AH+ F D VT S D + K+W T
Sbjct: 82 DKTVRIWVPNVKGESTV----FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKF 137
Query: 215 LRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L L + WV A F+ D R + + S D +LW+ YC H +T + F
Sbjct: 138 LFSLSQHIN-WVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 195
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 9/224 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMV 109
V+ V F +G + +G D T RIW P + +F+ A V +V D +
Sbjct: 64 VTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST---VFRAHTATVRSVHFCSDGQSFVT 120
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPH 169
+ +W + + + ++ P G+++ + ++ +W S +
Sbjct: 121 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSREC- 179
Query: 170 PVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA 229
H + F P T + D + K+W LL+ + + V
Sbjct: 180 ---VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAA-VNGL 235
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+F +L T SSDS ++ ++ G L GHQ T +AF
Sbjct: 236 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAF 279
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/248 (22%), Positives = 89/248 (35%), Gaps = 15/248 (6%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+ V + SP+ + A+G + + T F + V V F +G T
Sbjct: 62 DAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTA 121
Query: 67 GEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAV---MLHPDQSQIMVGDQSGIIHIWDLK 122
+D T ++W T QK +F + +N V PD I+ + +WD
Sbjct: 122 SDDKTVKVW------ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS 175
Query: 123 TDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKY 182
+ + E + + P+G +AA VW + H + +H HS
Sbjct: 176 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR---THRL-LQHYQLHSAA 231
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
F P L+T S D + KI + LL L Q AF+ + +G
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL-HGHQGPATTVAFSRTGEYFASGG 290
Query: 243 SDSYARLW 250
SD +W
Sbjct: 291 SDEQVMVW 298
>BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein.
Length = 359
Score = 57.6 bits (133), Expect = 4e-08
Identities = 39/179 (21%), Positives = 67/179 (37%), Gaps = 5/179 (2%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V V + Q+ G + +W +K + ++ + P+G ++A+ +
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWAL 214
+W + + V AH+ F D VT S D + K+W T
Sbjct: 82 DKTVRIWVPNVKGESTV----FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKF 137
Query: 215 LRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L L + WV A F+ D R + + S D +LW+ YC H +T + F
Sbjct: 138 LFSLSQHIN-WVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 195
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 9/224 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMV 109
V+ V F +G + +G D T RIW P + +F+ A V +V D +
Sbjct: 64 VTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST---VFRAHTATVRSVHFCSDGQSFVT 120
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPH 169
+ +W + + + ++ P G+++ + ++ +W S +
Sbjct: 121 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSREC- 179
Query: 170 PVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA 229
H + F P T + D + K+W LL+ + + V
Sbjct: 180 ---VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAA-VNGL 235
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+F +L T SSDS ++ ++ G L GHQ T +AF
Sbjct: 236 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAF 279
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/248 (22%), Positives = 89/248 (35%), Gaps = 15/248 (6%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+ V + SP+ + A+G + + T F + V V F +G T
Sbjct: 62 DAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTA 121
Query: 67 GEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAV---MLHPDQSQIMVGDQSGIIHIWDLK 122
+D T ++W T QK +F + +N V PD I+ + +WD
Sbjct: 122 SDDKTVKVW------ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS 175
Query: 123 TDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKY 182
+ + E + + P+G +AA VW + H + +H HS
Sbjct: 176 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR---THRL-LQHYQLHSAA 231
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
F P L+T S D + KI + LL L Q AF+ + +G
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL-HGHQGPATTVAFSRTGEYFASGG 290
Query: 243 SDSYARLW 250
SD +W
Sbjct: 291 SDEQVMVW 298
>BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein.
Length = 327
Score = 57.6 bits (133), Expect = 4e-08
Identities = 48/198 (24%), Positives = 77/198 (38%), Gaps = 11/198 (5%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T RIWD R T+C + + PD I VG++ ++ D KT
Sbjct: 117 TASGDKTIRIWDVRT---TKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTH 173
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
+++ + + + +I+ + M N G + S P P + I AH +
Sbjct: 174 RSKAE-EQFKFEVNEISWNNDNNMFFLTNGNGCINILSY----PELKPVQSINAHPSNCI 228
Query: 185 RCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRW-VWDAAFTLDSRFLFTGSS 243
KF P T S D +W + +R R W V +F+ D + L + S
Sbjct: 229 CIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSR--LDWPVRTLSFSHDGKMLASASE 286
Query: 244 DSYARLWNIERGTLEREY 261
D + + +E G R Y
Sbjct: 287 DHFIDIAEVETGNFMRIY 304
>BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein.
Length = 396
Score = 57.6 bits (133), Expect = 4e-08
Identities = 39/179 (21%), Positives = 67/179 (37%), Gaps = 5/179 (2%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V V + Q+ G + +W +K + ++ + P+G ++A+ +
Sbjct: 11 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 70
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWAL 214
+W + + V AH+ F D VT S D + K+W T
Sbjct: 71 DKTVRIWVPNVKGESTV----FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKF 126
Query: 215 LRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L L + WV A F+ D R + + S D +LW+ YC H +T + F
Sbjct: 127 LFSLSQHIN-WVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 184
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/224 (20%), Positives = 84/224 (37%), Gaps = 9/224 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMV 109
V+ V F +G + +G D T RIW P + +F+ A V +V D +
Sbjct: 53 VTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST---VFRAHTATVRSVHFCSDGQSFVT 109
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPH 169
+ +W + + + ++ P G+++ + ++ +W S +
Sbjct: 110 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSREC- 168
Query: 170 PVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA 229
H + F P T + D + K+W LL+ + + V
Sbjct: 169 ---VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAA-VNGL 224
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+F +L T SSDS ++ ++ G L GHQ T +AF
Sbjct: 225 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAF 268
Score = 51.6 bits (118), Expect = 3e-06
Identities = 55/248 (22%), Positives = 89/248 (35%), Gaps = 15/248 (6%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+ V + SP+ + A+G + + T F + V V F +G T
Sbjct: 51 DAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTA 110
Query: 67 GEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAV---MLHPDQSQIMVGDQSGIIHIWDLK 122
+D T ++W T QK +F + +N V PD I+ + +WD
Sbjct: 111 SDDKTVKVW------ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS 164
Query: 123 TDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKY 182
+ + E + + P+G +AA VW + H + +H HS
Sbjct: 165 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVR---THRL-LQHYQLHSAA 220
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
F P L+T S D + KI + LL L Q AF+ + +G
Sbjct: 221 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL-HGHQGPATTVAFSRTGEYFASGG 279
Query: 243 SDSYARLW 250
SD +W
Sbjct: 280 SDEQVMVW 287
>AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens
cDNA FLJ90808 fis, clone Y79AA1000777, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 407
Score = 57.6 bits (133), Expect = 4e-08
Identities = 39/179 (21%), Positives = 67/179 (37%), Gaps = 5/179 (2%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V V + Q+ G + +W +K + ++ + P+G ++A+ +
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWAL 214
+W + + V AH+ F D VT S D + K+W T
Sbjct: 82 DKTVRIWVPNVKGESTV----FRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKF 137
Query: 215 LRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L L + WV A F+ D R + + S D +LW+ YC H +T + F
Sbjct: 138 LFSLSQHIN-WVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDF 195
Score = 55.6 bits (128), Expect = 2e-07
Identities = 46/224 (20%), Positives = 85/224 (37%), Gaps = 9/224 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMV 109
V+ V F +G + +G D T RIW P + +F+ A V +V D +
Sbjct: 64 VTCVNFSPSGHLLASGSRDKTVRIWVPNVKGEST---VFRAHTATVRSVHFCSDGQSFVT 120
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPH 169
+ +W + + + ++ P G+++ + ++ +W S +
Sbjct: 121 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSREC- 179
Query: 170 PVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA 229
H + F P T + D + K+W + LL+ + + V
Sbjct: 180 ---VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAA-VNGL 235
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+F +L T SSDS ++ ++ G L GHQ T +AF
Sbjct: 236 SFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAF 279
Score = 49.6 bits (113), Expect = 1e-05
Identities = 54/248 (21%), Positives = 87/248 (35%), Gaps = 15/248 (6%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+ V + SP+ + A+G + + T F + V V F +G T
Sbjct: 62 DAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTA 121
Query: 67 GEDCTARIWDPRAAPRTRCQK-IFQVQAPVNAV---MLHPDQSQIMVGDQSGIIHIWDLK 122
+D T ++W T QK +F + +N V PD I+ + +WD
Sbjct: 122 SDDKTVKVW------ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKS 175
Query: 123 TDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKY 182
+ + E + + P+G +AA VW + +H HS
Sbjct: 176 SRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYR----LLQHYQLHSAA 231
Query: 183 ALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
F P L+T S D + KI + LL L Q AF+ + +G
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTL-HGHQGPATTVAFSRTGEYFASGG 290
Query: 243 SDSYARLW 250
SD +W
Sbjct: 291 SDEQVMVW 298
>AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 57.6 bits (133), Expect = 4e-08
Identities = 46/173 (26%), Positives = 77/173 (44%), Gaps = 9/173 (5%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 954 QSRFQHKKTVWRIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1012
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1013 PRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1066
Query: 205 KIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
KIW L EL R V +AF++DS L TG + R+WN+ G L
Sbjct: 1067 KIWSFDLLLPLHEL-RGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGEL 1118
Score = 48.0 bits (109), Expect = 4e-05
Identities = 30/100 (30%), Positives = 43/100 (43%), Gaps = 3/100 (3%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 653 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 711
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L TGSSD + +LW++ + GH ++ F
Sbjct: 712 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRF 751
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 842 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 897
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 898 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 951
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K R +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 952 IFQSRFQ-HKKTVWRIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1007
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+ R L + S D ++WNI G E+++ HQ +
Sbjct: 1008 RLLKNPRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1045
Score = 44.4 bits (100), Expect = 4e-04
Identities = 53/256 (20%), Positives = 99/256 (38%), Gaps = 19/256 (7%)
Query: 8 QVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
QV+ +SP A G ++ + L N + K V R+ F + + +
Sbjct: 920 QVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWRIQFTADEKTLISSS 979
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
+D ++W+ + +C + Q V L + +++ G + +W++ T E
Sbjct: 980 DDAEIQVWNWQL---DKCIFLRGHQETVKDFRLLKNP-RLLSWSFDGTVKVWNIITGNKE 1035
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ + ++ I ++ + +WS +P + H+ +RC
Sbjct: 1036 KDFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFDLL----LPLHELRGHNG-CVRCS 1090
Query: 188 -FSPDSTMLVTTSGDCSAKIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLF 239
FS DST+L T + +IW S+ LL E WV D F+ D + L
Sbjct: 1091 AFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI 1150
Query: 240 TGSSDSYARLWNIERG 255
S+ Y + WN+ G
Sbjct: 1151 --SAGGYIKWWNVVTG 1164
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 611 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 669
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 707
Score = 39.5 bits (88), Expect = 0.013
Identities = 44/193 (22%), Positives = 72/193 (37%), Gaps = 26/193 (13%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 685 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 741
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 742 HTNSVNHCRFSPDDKLLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 799
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI--------------TAHSKYALRCKFSPDSTMLV 196
V C WS G K I H + FSPD + +
Sbjct: 800 IVK----CCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL 855
Query: 197 TTSGDCSAKIWRT 209
T+S D + ++W T
Sbjct: 856 TSSDDQTIRLWET 868
Score = 32.7 bits (71), Expect = 1.5
Identities = 28/157 (17%), Positives = 61/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 623 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 677
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 678 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 735
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD +L + S D + K+W
Sbjct: 736 --RNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLW 770
>AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein.
Length = 514
Score = 57.6 bits (133), Expect = 4e-08
Identities = 56/234 (23%), Positives = 95/234 (40%), Gaps = 16/234 (6%)
Query: 48 SKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQI 107
+K+V+ + + GT + TG D ARIW + Q + P+ A+ + + I
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWTKDG---NLASTLGQHKGPIFALKWNKKGNFI 281
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQP 167
+ IWD T + +Q P A D+ + A+ + +V L GQ
Sbjct: 282 LSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-SNNTFASCSTDMCIHVCKL-GQD 339
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD-----T 222
P K H+ K+ P +L + S D + KIW + +L++ T
Sbjct: 340 R---PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQQHNKEIYT 396
Query: 223 QRWVWDAAFTLDSR---FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+W T + L + S DS RLW+++RG HQ+ + ++AF
Sbjct: 397 IKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 450
Score = 56.4 bits (130), Expect = 1e-07
Identities = 52/217 (23%), Positives = 88/217 (40%), Gaps = 17/217 (7%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGI 115
+ K G ++ + G D T IWD + Q F AP V + +
Sbjct: 274 WNKKGNFILSAGVDKTTIIWDAHTG-EAKQQFPFH-SAPALDVDWQSNNTFASCSTDM-C 330
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKH 175
IH+ L D+ + + I DP G ++A+ ++ +WS+ + + V
Sbjct: 331 IHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSM--KQDNCV--HD 386
Query: 176 ITAHSKYALRCKFSPD---------STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
+ H+K K+SP + ML + S D + ++W + L + Q V
Sbjct: 387 LQQHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKH-QEPV 445
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCG 263
+ AF+ D R+L +GS D +WN + G L Y G
Sbjct: 446 YSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482
Score = 37.5 bits (83), Expect = 0.051
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 14/109 (12%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD-------WALLRELRRD------T 222
+ H C ++P S +L + SGD +A+IW S+ +LR R+ +
Sbjct: 165 LRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPS 224
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
+ V + + L TGS D +AR+W + G L H+ I AL
Sbjct: 225 NKDVTSLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPIFAL 272
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/130 (14%), Positives = 57/130 (43%), Gaps = 7/130 (5%)
Query: 40 PVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAP-----RTRCQKIFQVQ-A 93
P+ TF+ + V+ + + G + + +D T +IW + + ++I+ ++ +
Sbjct: 341 PIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQQHNKEIYTIKWS 400
Query: 94 PVNAVMLHPDQSQIMVGDQ-SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAV 152
P +P+ + ++ + +WD+ + + + + +A P G+ +A+
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460
Query: 153 NNKGNCYVWS 162
+ ++W+
Sbjct: 461 SFDKCVHIWN 470
>BC032551-1|AAH32551.1| 795|Homo sapiens phospholipase
A2-activating protein protein.
Length = 795
Score = 57.2 bits (132), Expect = 6e-08
Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 22/244 (9%)
Query: 9 VNSLEISPTSMVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+ S +I P ++A G H I ++ L S P P+ + V + K GT + +G
Sbjct: 74 IPSSDIYPHGLIATGGNDHNICIFSLDS--PMPLYILKGHKNTVCSLSSGKFGT-LLSGS 130
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
D TA++W +C Q A V AV + P+Q ++ G + +W K +
Sbjct: 131 WDTTAKVW-----LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLW--KAGRC 183
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
E+ E ++ +AI + ++ N+ + W ++G+ + H+ Y
Sbjct: 184 ERTFSGHEDCVRGLAILSETEFLSCAND-ASIRRWQITGEC-----LEVYYGHTNYIYSI 237
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
P+ VTT+ D S +IW+ + A + +R Q +W LD+ + G+SD
Sbjct: 238 SVFPNCRDFVTTAEDRSLRIWKHGECA--QTIRLPAQS-IW-CCCVLDNGDIVVGASDGI 293
Query: 247 ARLW 250
R++
Sbjct: 294 IRVF 297
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 11/131 (8%)
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
I P G ++A N N ++SL P+P + H T+L + S D
Sbjct: 79 IYPHG-LIATGGNDHNICIFSLDS----PMPLYILKGHKNTVCSLSSGKFGTLL-SGSWD 132
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
+AK+W +D ++ L+ T VW + + TGS+D +LW + G ER +
Sbjct: 133 TTAKVW-LNDKCMMT-LQGHTAA-VWAVKILPEQGLMLTGSADKTVKLW--KAGRCERTF 187
Query: 262 CGHQKAITALA 272
GH+ + LA
Sbjct: 188 SGHEDCVRGLA 198
>AL356133-3|CAH72641.1| 738|Homo sapiens phospholipase
A2-activating protein protein.
Length = 738
Score = 57.2 bits (132), Expect = 6e-08
Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 22/244 (9%)
Query: 9 VNSLEISPTSMVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+ S +I P ++A G H I ++ L S P P+ + V + K GT + +G
Sbjct: 17 IPSSDIYPHGLIATGGNDHNICIFSLDS--PMPLYILKGHKNTVCSLSSGKFGT-LLSGS 73
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
D TA++W +C Q A V AV + P+Q ++ G + +W K +
Sbjct: 74 WDTTAKVW-----LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLW--KAGRC 126
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
E+ E ++ +AI + ++ N+ + W ++G+ + H+ Y
Sbjct: 127 ERTFSGHEDCVRGLAILSETEFLSCAND-ASIRRWQITGEC-----LEVYYGHTNYIYSI 180
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
P+ VTT+ D S +IW+ + A + +R Q +W LD+ + G+SD
Sbjct: 181 SVFPNCRDFVTTAEDRSLRIWKHGECA--QTIRLPAQS-IW-CCCVLDNGDIVVGASDGI 236
Query: 247 ARLW 250
R++
Sbjct: 237 IRVF 240
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 11/131 (8%)
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
I P G ++A N N ++SL P+P + H T+L + S D
Sbjct: 22 IYPHG-LIATGGNDHNICIFSLDS----PMPLYILKGHKNTVCSLSSGKFGTLL-SGSWD 75
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
+AK+W +D ++ L+ T VW + + TGS+D +LW + G ER +
Sbjct: 76 TTAKVW-LNDKCMMT-LQGHTAA-VWAVKILPEQGLMLTGSADKTVKLW--KAGRCERTF 130
Query: 262 CGHQKAITALA 272
GH+ + LA
Sbjct: 131 SGHEDCVRGLA 141
>AK223544-1|BAD97264.1| 748|Homo sapiens Hypothetical protein
DKFZp434J1217 (PLAA protein) (OTTHUMP00000045176)
variant protein.
Length = 748
Score = 57.2 bits (132), Expect = 6e-08
Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 22/244 (9%)
Query: 9 VNSLEISPTSMVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+ S +I P ++A G H I ++ L S P P+ + V + K GT + +G
Sbjct: 27 IPSSDIYPHGLIATGGNDHNICIFSLDS--PMPLYILKGHKNTVCSLSSGKFGT-LLSGS 83
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
D TA++W +C Q A V AV + P+Q ++ G + +W K +
Sbjct: 84 WDTTAKVW-----LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLW--KAGRC 136
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
E+ E ++ +AI + ++ N+ + W ++G+ + H+ Y
Sbjct: 137 ERTFSGHEDCVRGLAILSETEFLSCAND-ASIRRWQITGEC-----LEVYYGHTNYIYSI 190
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
P+ VTT+ D S +IW+ + A + +R Q +W LD+ + G+SD
Sbjct: 191 SVFPNCRDFVTTAEDRSLRIWKHGECA--QTIRLPAQS-IW-CCCVLDNGDIVVGASDGI 246
Query: 247 ARLW 250
R++
Sbjct: 247 IRVF 250
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 11/131 (8%)
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
I P G ++A N N ++SL P+P + H T+L + S D
Sbjct: 32 IYPHG-LIATGGNDHNICIFSLDS----PMPLYILKGHKNTVCSLSSGKFGTLL-SGSWD 85
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
+AK+W +D ++ L+ T VW + + TGS+D +LW + G ER +
Sbjct: 86 TTAKVW-LNDKCMMT-LQGHTAA-VWAVKILPEQGLMLTGSADKTVKLW--KAGRCERTF 140
Query: 262 CGHQKAITALA 272
GH+ + LA
Sbjct: 141 SGHEDCVRGLA 151
>AK002143-1|BAA92105.1| 544|Homo sapiens protein ( Homo sapiens
cDNA FLJ11281 fis, clone PLACE1009468, highly similar to
PHOSPHOLIPASE A-2-ACTIVATING PROTEIN. ).
Length = 544
Score = 57.2 bits (132), Expect = 6e-08
Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 22/244 (9%)
Query: 9 VNSLEISPTSMVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+ S +I P ++A G H I ++ L S P P+ + V + K GT + +G
Sbjct: 74 IPSSDIYPHGLIATGGNDHNICIFSLDS--PMPLYILKGHKNTVCSLSSGKFGT-LLSGS 130
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
D TA++W +C Q A V AV + P+Q ++ G + +W K +
Sbjct: 131 WDTTAKVW-----LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLW--KAGRC 183
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
E+ E ++ +AI + ++ N+ + W ++G+ + H+ Y
Sbjct: 184 ERTFSGHEDCVRGLAILSETEFLSCAND-ASIRRWQITGEC-----LEVYYGHTNYIYSI 237
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
P+ VTT+ D S +IW+ + A + +R Q +W LD+ + G+SD
Sbjct: 238 SVFPNCRDFVTTAEDRSLRIWKHGECA--QTIRLPAQS-IW-CCCVLDNGDIVVGASDGI 293
Query: 247 ARLW 250
R++
Sbjct: 294 IRVF 297
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 11/131 (8%)
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
I P G ++A N N ++SL P+P + H T+L + S D
Sbjct: 79 IYPHG-LIATGGNDHNICIFSLDS----PMPLYILKGHKNTVCSLSSGKFGTLL-SGSWD 132
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
+AK+W +D ++ L+ T VW + + TGS+D +LW + G ER +
Sbjct: 133 TTAKVW-LNDKCMMT-LQGHTAA-VWAVKILPEQGLMLTGSADKTVKLW--KAGRCERTF 187
Query: 262 CGHQKAITALA 272
GH+ + LA
Sbjct: 188 SGHEDCVRGLA 198
>AK001642-1|BAA91803.1| 795|Homo sapiens protein ( Homo sapiens
cDNA FLJ10780 fis, clone NT2RP4000376, highly similar to
Homo sapiens mRNA for phospholipase A2 activating
protein. ).
Length = 795
Score = 57.2 bits (132), Expect = 6e-08
Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 22/244 (9%)
Query: 9 VNSLEISPTSMVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+ S +I P ++A G H I ++ L S P P+ + V + K GT + +G
Sbjct: 74 IPSSDIYPHGLIATGGNDHNICIFSLDS--PMPLYILKGHKNTVCSLSSGKFGT-LLSGS 130
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
D TA++W +C Q A V AV + P+Q ++ G + +W K +
Sbjct: 131 WDTTAKVW-----LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSAGKTVKLW--KAGRC 183
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
E+ E ++ +AI + ++ N+ + W ++G+ + H+ Y
Sbjct: 184 ERTFSGHEDCVRGLAILSETEFLSCAND-ASIRRWQITGEC-----LEVYYGHTNYIYSI 237
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
P+ VTT+ D S +IW+ + A + +R Q +W LD+ + G+SD
Sbjct: 238 SVFPNCRDFVTTAEDRSLRIWKHGECA--QTIRLPAQS-IW-CCCVLDNGDIVVGASDGI 293
Query: 247 ARLW 250
R++
Sbjct: 294 IRVF 297
Score = 39.1 bits (87), Expect = 0.017
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 11/131 (8%)
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
I P G ++A N N ++SL P+P + H T+L + S D
Sbjct: 79 IYPHG-LIATGGNDHNICIFSLDS----PMPLYILKGHKNTVCSLSSGKFGTLL-SGSWD 132
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
+AK+W +D ++ L+ T VW + + TGS+ +LW + G ER +
Sbjct: 133 TTAKVW-LNDKCMMT-LQGHTAA-VWAVKILPEQGLMLTGSAGKTVKLW--KAGRCERTF 187
Query: 262 CGHQKAITALA 272
GH+ + LA
Sbjct: 188 SGHEDCVRGLA 198
>AJ238243-1|CAB42881.1| 738|Homo sapiens phospholipase A2
activating protein protein.
Length = 738
Score = 57.2 bits (132), Expect = 6e-08
Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 22/244 (9%)
Query: 9 VNSLEISPTSMVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+ S +I P ++A G H I ++ L S P P+ + V + K GT + +G
Sbjct: 17 IPSSDIYPHGLIATGGNDHNICIFSLDS--PMPLYILKGHKNTVCSLSSGKFGT-LLSGS 73
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
D TA++W +C Q A V AV + P+Q ++ G + +W K +
Sbjct: 74 WDTTAKVW-----LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLW--KAGRC 126
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
E+ E ++ +AI + ++ N+ + W ++G+ + H+ Y
Sbjct: 127 ERTFSGHEDCVRGLAILSETEFLSCAND-ASIRRWQITGEC-----LEVYYGHTNYIYSI 180
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
P+ VTT+ D S +IW+ + A + +R Q +W LD+ + G+SD
Sbjct: 181 SVFPNCRDFVTTAEDRSLRIWKHGECA--QTIRLPAQS-IW-CCCVLDNGDIVVGASDGI 236
Query: 247 ARLW 250
R++
Sbjct: 237 IRVF 240
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 11/131 (8%)
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
I P G ++A N N ++SL P+P + H T+L + S D
Sbjct: 22 IYPHG-LIATGGNDHNICIFSLDS----PMPLYILKGHKNTVCSLSSGKFGTLL-SGSWD 75
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
+AK+W +D ++ L+ T VW + + TGS+D +LW + G ER +
Sbjct: 76 TTAKVW-LNDKCMMT-LQGHTAA-VWAVKILPEQGLMLTGSADKTVKLW--KAGRCERTF 130
Query: 262 CGHQKAITALA 272
GH+ + LA
Sbjct: 131 SGHEDCVRGLA 141
>AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kDa
protein protein.
Length = 357
Score = 57.2 bits (132), Expect = 6e-08
Identities = 45/201 (22%), Positives = 84/201 (41%), Gaps = 8/201 (3%)
Query: 57 QKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGII 116
+K+ + TG +D T ++WD R + + FQ V AV + QI+ G I
Sbjct: 161 RKSPQLVCTGSDDGTVKLWDIR---KKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDI 217
Query: 117 HIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP----VP 172
+WDL+ ++ + S+ +++ G + + VW + P +
Sbjct: 218 KVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIF 277
Query: 173 KKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFT 232
+ ++ K LRC +SPD + + S D +W T+ +L +L + + AF
Sbjct: 278 QGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGS-INEVAFH 336
Query: 233 LDSRFLFTGSSDSYARLWNIE 253
D + + SSD + I+
Sbjct: 337 PDEPIIISASSDKRLYMGEIQ 357
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/161 (23%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Query: 8 QVNSLEISPTS-MVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
QV ++ + TS + + G + I+++DL T + +V+ + G+++ +
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL--TYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 66 GGEDCTARIWDPRA-APRTRCQKIFQ-----VQAPVNAVMLHPDQSQIMVGDQSGIIHIW 119
D T R+WD R AP+ RC KIFQ + + PD S+I G +++W
Sbjct: 253 NAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 312
Query: 120 DLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
D + + +P SI ++A P ++ + ++ Y+
Sbjct: 313 DTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/188 (20%), Positives = 77/188 (40%), Gaps = 10/188 (5%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD-QNEQLIPEAEASIQDIAIDPAGKMMA 150
+ V HP+ S + +I +W++ D N + ++ ++ + G M+
Sbjct: 66 EGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLF 125
Query: 151 AVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT-SGDCSAKIWR 208
+ + VW S +G+ K + H+ + C + S LV T S D + K+W
Sbjct: 126 SASTDKTVAVWDSETGERV-----KRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWD 180
Query: 209 TSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
A ++ + Q V F S + +G D+ ++W++ + L GH ++
Sbjct: 181 IRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSV 238
Query: 269 TALAFKDQ 276
T L+ +
Sbjct: 239 TGLSLSSE 246
Score = 44.0 bits (99), Expect = 6e-04
Identities = 48/271 (17%), Positives = 114/271 (42%), Gaps = 18/271 (6%)
Query: 18 SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDP 77
S +A+AGF + L + D T + S V + + +G+ +++ D T +WD
Sbjct: 79 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138
Query: 78 RAAPRTRCQKIFQVQAPVNAVMLHPDQSQIM-VGDQSGIIHIWDLKTDQNEQLIPEAEAS 136
R + ++ + VN+ Q++ G G + +WD++ Q
Sbjct: 139 ETGERVK--RLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQV 196
Query: 137 IQDIAIDPAGKMMAA-VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
+ D + ++++ ++N + VW L + H + + +L S + + L
Sbjct: 197 LAVTFNDTSDQIISGGIDN--DIKVWDLRQNKLTYTMRGHADSVTGLSL----SSEGSYL 250
Query: 196 VTTSGDCSAKIWRTSDWA-------LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
++ + D + ++W +A + + + ++ + +++ D + GS+D +
Sbjct: 251 LSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVY 310
Query: 249 LWNIERGTLEREYCGHQKAITALAF-KDQPV 278
+W+ + + GH +I +AF D+P+
Sbjct: 311 VWDTTSRRILYKLPGHAGSINEVAFHPDEPI 341
Score = 34.3 bits (75), Expect = 0.48
Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLD 234
++ H CKF P+ + L + D +W D L+ + V + + D
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGA-VMELHYNTD 120
Query: 235 SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
LF+ S+D +W+ E G + GH + +
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNS 156
>AF083395-1|AAD03030.1| 738|Homo sapiens phospholipase
A2-activating protein protein.
Length = 738
Score = 57.2 bits (132), Expect = 6e-08
Identities = 58/244 (23%), Positives = 106/244 (43%), Gaps = 22/244 (9%)
Query: 9 VNSLEISPTSMVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGG 67
+ S +I P ++A G H I ++ L S P P+ + V + K GT + +G
Sbjct: 17 IPSSDIYPHGLIATGGNDHNICIFSLDS--PMPLYILKGHKNTVCSLSSGKFGT-LLSGS 73
Query: 68 EDCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
D TA++W +C Q A V AV + P+Q ++ G + +W K +
Sbjct: 74 WDTTAKVW-----LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLW--KAGRC 126
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
E+ E ++ +AI + ++ N+ + W ++G+ + H+ Y
Sbjct: 127 ERTFSGHEDCVRGLAILSETEFLSCAND-ASIRRWQITGEC-----LEVYYGHTNYIYSI 180
Query: 187 KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSY 246
P+ VTT+ D S +IW+ + A + +R Q +W LD+ + G+SD
Sbjct: 181 SVFPNCRDFVTTAEDRSLRIWKHGECA--QTIRLPAQS-IW-CCCVLDNGDIVVGASDGI 236
Query: 247 ARLW 250
R++
Sbjct: 237 IRVF 240
Score = 41.9 bits (94), Expect = 0.002
Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 11/131 (8%)
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
I P G ++A N N ++SL P+P + H T+L + S D
Sbjct: 22 IYPHG-LIATGGNDHNICIFSLDS----PMPLYILKGHKNTVCSLSSGKFGTLL-SGSWD 75
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
+AK+W +D ++ L+ T VW + + TGS+D +LW + G ER +
Sbjct: 76 TTAKVW-LNDKCMMT-LQGHTAA-VWAVKILPEQGLMLTGSADKTVKLW--KAGRCERTF 130
Query: 262 CGHQKAITALA 272
GH+ + LA
Sbjct: 131 SGHEDCVRGLA 141
>EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein.
Length = 357
Score = 56.8 bits (131), Expect = 8e-08
Identities = 44/193 (22%), Positives = 80/193 (41%), Gaps = 8/193 (4%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
TG +D T ++WD R + + FQ V AV + QI+ G I +WDL+ +
Sbjct: 169 TGSDDGTVKLWDIR---KKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQN 225
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP----VPKKHITAHS 180
+ + S+ +++ G + + VW + P + + ++
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFE 285
Query: 181 KYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFT 240
K LRC +SPD + + S D +W T+ +L +L + + AF D + +
Sbjct: 286 KNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGS-INEVAFHPDEPIIIS 344
Query: 241 GSSDSYARLWNIE 253
SSD + I+
Sbjct: 345 ASSDKRLYMGEIQ 357
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/161 (23%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Query: 8 QVNSLEISPTS-MVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
QV ++ + TS + + G + I+++DL T + +V+ + G+++ +
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL--TYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 66 GGEDCTARIWDPRA-APRTRCQKIFQ-----VQAPVNAVMLHPDQSQIMVGDQSGIIHIW 119
D T R+WD R AP+ RC KIFQ + + PD S+I G +++W
Sbjct: 253 NAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 312
Query: 120 DLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
D + + +P SI ++A P ++ + ++ Y+
Sbjct: 313 DTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/188 (19%), Positives = 76/188 (40%), Gaps = 10/188 (5%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD-QNEQLIPEAEASIQDIAIDPAGKMMA 150
+ V HP+ S + +I +W++ D N + ++ ++ + G M+
Sbjct: 66 EGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLF 125
Query: 151 AVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT-SGDCSAKIWR 208
+ + VW S +G+ K + H+ + C + LV T S D + K+W
Sbjct: 126 SASTDKTVAVWDSETGERV-----KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 180
Query: 209 TSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
A ++ + Q V F S + +G D+ ++W++ + L GH ++
Sbjct: 181 IRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSV 238
Query: 269 TALAFKDQ 276
T L+ +
Sbjct: 239 TGLSLSSE 246
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/271 (17%), Positives = 114/271 (42%), Gaps = 18/271 (6%)
Query: 18 SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDP 77
S +A+AGF + L + D T + S V + + +G+ +++ D T +WD
Sbjct: 79 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138
Query: 78 RAAPRTRCQKIFQVQAPVNAVMLHPDQSQIM-VGDQSGIIHIWDLKTDQNEQLIPEAEAS 136
R + ++ + VN+ Q++ G G + +WD++ Q
Sbjct: 139 ETGERVK--RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQV 196
Query: 137 IQDIAIDPAGKMMAA-VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
+ D + ++++ ++N + VW L + H + + +L S + + L
Sbjct: 197 LAVTFNDTSDQIISGGIDN--DIKVWDLRQNKLTYTMRGHADSVTGLSL----SSEGSYL 250
Query: 196 VTTSGDCSAKIWRTSDWA-------LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
++ + D + ++W +A + + + ++ + +++ D + GS+D +
Sbjct: 251 LSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVY 310
Query: 249 LWNIERGTLEREYCGHQKAITALAF-KDQPV 278
+W+ + + GH +I +AF D+P+
Sbjct: 311 VWDTTSRRILYKLPGHAGSINEVAFHPDEPI 341
Score = 34.3 bits (75), Expect = 0.48
Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLD 234
++ H CKF P+ + L + D +W D L+ + V + + D
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGA-VMELHYNTD 120
Query: 235 SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
LF+ S+D +W+ E G + GH + +
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNS 156
>BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 56.8 bits (131), Expect = 8e-08
Identities = 44/193 (22%), Positives = 80/193 (41%), Gaps = 8/193 (4%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
TG +D T ++WD R + + FQ V AV + QI+ G I +WDL+ +
Sbjct: 169 TGSDDGTVKLWDIR---KKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQN 225
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP----VPKKHITAHS 180
+ + S+ +++ G + + VW + P + + ++
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFE 285
Query: 181 KYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFT 240
K LRC +SPD + + S D +W T+ +L +L + + AF D + +
Sbjct: 286 KNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGS-INEVAFHPDEPIIIS 344
Query: 241 GSSDSYARLWNIE 253
SSD + I+
Sbjct: 345 ASSDKRLYMGEIQ 357
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/161 (23%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Query: 8 QVNSLEISPTS-MVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
QV ++ + TS + + G + I+++DL T + +V+ + G+++ +
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL--TYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 66 GGEDCTARIWDPRA-APRTRCQKIFQ-----VQAPVNAVMLHPDQSQIMVGDQSGIIHIW 119
D T R+WD R AP+ RC KIFQ + + PD S+I G +++W
Sbjct: 253 NAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 312
Query: 120 DLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
D + + +P SI ++A P ++ + ++ Y+
Sbjct: 313 DTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/188 (19%), Positives = 76/188 (40%), Gaps = 10/188 (5%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD-QNEQLIPEAEASIQDIAIDPAGKMMA 150
+ V HP+ S + +I +W++ D N + ++ ++ + G M+
Sbjct: 66 EGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLF 125
Query: 151 AVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT-SGDCSAKIWR 208
+ + VW S +G+ K + H+ + C + LV T S D + K+W
Sbjct: 126 SASTDKTVAVWDSETGERV-----KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 180
Query: 209 TSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
A ++ + Q V F S + +G D+ ++W++ + L GH ++
Sbjct: 181 IRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSV 238
Query: 269 TALAFKDQ 276
T L+ +
Sbjct: 239 TGLSLSSE 246
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/271 (17%), Positives = 114/271 (42%), Gaps = 18/271 (6%)
Query: 18 SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDP 77
S +A+AGF + L + D T + S V + + +G+ +++ D T +WD
Sbjct: 79 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138
Query: 78 RAAPRTRCQKIFQVQAPVNAVMLHPDQSQIM-VGDQSGIIHIWDLKTDQNEQLIPEAEAS 136
R + ++ + VN+ Q++ G G + +WD++ Q
Sbjct: 139 ETGERVK--RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQV 196
Query: 137 IQDIAIDPAGKMMAA-VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
+ D + ++++ ++N + VW L + H + + +L S + + L
Sbjct: 197 LAVTFNDTSDQIISGGIDN--DIKVWDLRQNKLTYTMRGHADSVTGLSL----SSEGSYL 250
Query: 196 VTTSGDCSAKIWRTSDWA-------LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
++ + D + ++W +A + + + ++ + +++ D + GS+D +
Sbjct: 251 LSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVY 310
Query: 249 LWNIERGTLEREYCGHQKAITALAF-KDQPV 278
+W+ + + GH +I +AF D+P+
Sbjct: 311 VWDTTSRRILYKLPGHAGSINEVAFHPDEPI 341
Score = 34.3 bits (75), Expect = 0.48
Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLD 234
++ H CKF P+ + L + D +W D L+ + V + + D
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGA-VMELHYNTD 120
Query: 235 SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
LF+ S+D +W+ E G + GH + +
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNS 156
>AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 56.8 bits (131), Expect = 8e-08
Identities = 44/193 (22%), Positives = 80/193 (41%), Gaps = 8/193 (4%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
TG +D T ++WD R + + FQ V AV + QI+ G I +WDL+ +
Sbjct: 169 TGSDDGTVKLWDIR---KKAAIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQN 225
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP----VPKKHITAHS 180
+ + S+ +++ G + + VW + P + + ++
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFE 285
Query: 181 KYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFT 240
K LRC +SPD + + S D +W T+ +L +L + + AF D + +
Sbjct: 286 KNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGS-INEVAFHPDEPIIIS 344
Query: 241 GSSDSYARLWNIE 253
SSD + I+
Sbjct: 345 ASSDKRLYMGEIQ 357
Score = 53.2 bits (122), Expect = 1e-06
Identities = 38/161 (23%), Positives = 74/161 (45%), Gaps = 10/161 (6%)
Query: 8 QVNSLEISPTS-MVAAAGFQH-IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
QV ++ + TS + + G + I+++DL T + +V+ + G+++ +
Sbjct: 195 QVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL--TYTMRGHADSVTGLSLSSEGSYLLS 252
Query: 66 GGEDCTARIWDPRA-APRTRCQKIFQ-----VQAPVNAVMLHPDQSQIMVGDQSGIIHIW 119
D T R+WD R AP+ RC KIFQ + + PD S+I G +++W
Sbjct: 253 NAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVW 312
Query: 120 DLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
D + + +P SI ++A P ++ + ++ Y+
Sbjct: 313 DTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 43.2 bits (97), Expect = 0.001
Identities = 37/188 (19%), Positives = 76/188 (40%), Gaps = 10/188 (5%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD-QNEQLIPEAEASIQDIAIDPAGKMMA 150
+ V HP+ S + +I +W++ D N + ++ ++ + G M+
Sbjct: 66 EGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLF 125
Query: 151 AVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT-SGDCSAKIWR 208
+ + VW S +G+ K + H+ + C + LV T S D + K+W
Sbjct: 126 SASTDKTVAVWDSETGERV-----KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 180
Query: 209 TSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
A ++ + Q V F S + +G D+ ++W++ + L GH ++
Sbjct: 181 IRKKAAIQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSV 238
Query: 269 TALAFKDQ 276
T L+ +
Sbjct: 239 TGLSLSSE 246
Score = 42.7 bits (96), Expect = 0.001
Identities = 48/271 (17%), Positives = 114/271 (42%), Gaps = 18/271 (6%)
Query: 18 SMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDP 77
S +A+AGF + L + D T + S V + + +G+ +++ D T +WD
Sbjct: 79 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138
Query: 78 RAAPRTRCQKIFQVQAPVNAVMLHPDQSQIM-VGDQSGIIHIWDLKTDQNEQLIPEAEAS 136
R + ++ + VN+ Q++ G G + +WD++ Q
Sbjct: 139 ETGERVK--RLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQV 196
Query: 137 IQDIAIDPAGKMMAA-VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
+ D + ++++ ++N + VW L + H + + +L S + + L
Sbjct: 197 LAVTFNDTSDQIISGGIDN--DIKVWDLRQNKLTYTMRGHADSVTGLSL----SSEGSYL 250
Query: 196 VTTSGDCSAKIWRTSDWA-------LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYAR 248
++ + D + ++W +A + + + ++ + +++ D + GS+D +
Sbjct: 251 LSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVY 310
Query: 249 LWNIERGTLEREYCGHQKAITALAF-KDQPV 278
+W+ + + GH +I +AF D+P+
Sbjct: 311 VWDTTSRRILYKLPGHAGSINEVAFHPDEPI 341
Score = 34.3 bits (75), Expect = 0.48
Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLD 234
++ H CKF P+ + L + D +W D L+ + V + + D
Sbjct: 62 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGA-VMELHYNTD 120
Query: 235 SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
LF+ S+D +W+ E G + GH + +
Sbjct: 121 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNS 156
>EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein.
Length = 513
Score = 56.4 bits (130), Expect = 1e-07
Identities = 45/174 (25%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 89 FQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ-NEQLIPEAEAS--IQDIAI--- 142
F ++ V PD ++ G G I +W+ T + + L +A+ + + D A+
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 143 --DPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+M+A G VW + SGQ ++ AHSK FS DS+ +++ S
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 200 GDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
D + +I L+E R + +V +A FT D ++ + SSD ++WN++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSS-FVNEATFTQDGHYIISASSDGTVKIWNMK 379
Score = 50.8 bits (116), Expect = 5e-06
Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 9/109 (8%)
Query: 174 KHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR---RDTQRWVWDA 229
+HI K + C +FSPD LVT S D ++W + + ++L+ +D + DA
Sbjct: 207 RHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDA 266
Query: 230 A----FTLDSRFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAF 273
F+ D+ L TG+ D ++W I+ G L R H K +T L+F
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSF 315
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 24/205 (11%)
Query: 17 TSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIW 75
+S + +A F Q IR++ L S + F S V+ F ++G ++ + D T +IW
Sbjct: 319 SSQILSASFDQTIRIHGLKSGKT--LKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIW 376
Query: 76 DPRAAPRTRCQKIFQ-------VQAPVNAVMLHPDQSQ-IMVGDQSGIIHIWDLKTDQNE 127
+ + T C F+ VN+V+L P + +V ++S + I +++ Q
Sbjct: 377 NMKT---TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQ-GQIV 432
Query: 128 QLIPEAEASIQDI---AIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAHSKYA 183
+ + D A+ P G+ + V Y +S ++G+ ++ +T H K
Sbjct: 433 RSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKL-----ERTLTVHEKDV 487
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWR 208
+ P ++ T S D K+W+
Sbjct: 488 IGIAHHPHQNLIATYSEDGLLKLWK 512
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/47 (29%), Positives = 25/47 (53%)
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
L R ++ + V A F+ D ++L TGS D + +WN G + ++
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKD 251
>BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 56.4 bits (130), Expect = 1e-07
Identities = 45/174 (25%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 89 FQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ-NEQLIPEAEAS--IQDIAI--- 142
F ++ V PD ++ G G I +W+ T + + L +A+ + + D A+
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 143 --DPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+M+A G VW + SGQ ++ AHSK FS DS+ +++ S
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 200 GDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
D + +I L+E R + +V +A FT D ++ + SSD ++WN++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSS-FVNEATFTQDGHYIISASSDGTVKIWNMK 379
Score = 50.8 bits (116), Expect = 5e-06
Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 9/109 (8%)
Query: 174 KHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR---RDTQRWVWDA 229
+HI K + C +FSPD LVT S D ++W + + ++L+ +D + DA
Sbjct: 207 RHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDA 266
Query: 230 A----FTLDSRFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAF 273
F+ D+ L TG+ D ++W I+ G L R H K +T L+F
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSF 315
Score = 40.7 bits (91), Expect = 0.005
Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 24/205 (11%)
Query: 17 TSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIW 75
+S + +A F Q IR++ L S + F S V+ F ++G ++ + D T +IW
Sbjct: 319 SSQILSASFDQTIRIHGLKSGKT--LKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIW 376
Query: 76 DPRAAPRTRCQKIFQ-------VQAPVNAVMLHPDQSQ-IMVGDQSGIIHIWDLKTDQNE 127
+ + T C F+ VN+V+L P + +V ++S + I +++ Q
Sbjct: 377 NMKT---TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQ-GQIV 432
Query: 128 QLIPEAEASIQDI---AIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAHSKYA 183
+ + D A+ P G+ + V Y +S ++G+ ++ +T H K
Sbjct: 433 RSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKL-----ERTLTVHEKDV 487
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWR 208
+ P ++ T S D K+W+
Sbjct: 488 IGIAHHPHQNLIATYSEDALLKLWK 512
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/47 (29%), Positives = 25/47 (53%)
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
L R ++ + V A F+ D ++L TGS D + +WN G + ++
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKD 251
>BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 56.4 bits (130), Expect = 1e-07
Identities = 45/174 (25%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 89 FQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ-NEQLIPEAEAS--IQDIAI--- 142
F ++ V PD ++ G G I +W+ T + + L +A+ + + D A+
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 143 --DPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+M+A G VW + SGQ ++ AHSK FS DS+ +++ S
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 200 GDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
D + +I L+E R + +V +A FT D ++ + SSD ++WN++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSS-FVNEATFTQDGHYIISASSDGTVKIWNMK 379
Score = 50.8 bits (116), Expect = 5e-06
Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 9/109 (8%)
Query: 174 KHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR---RDTQRWVWDA 229
+HI K + C +FSPD LVT S D ++W + + ++L+ +D + DA
Sbjct: 207 RHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDA 266
Query: 230 A----FTLDSRFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAF 273
F+ D+ L TG+ D ++W I+ G L R H K +T L+F
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSF 315
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 24/205 (11%)
Query: 17 TSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIW 75
+S + +A F Q IR++ L S + F S V+ F ++G ++ + D T +IW
Sbjct: 319 SSQILSASFDQTIRIHGLKSGKT--LKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIW 376
Query: 76 DPRAAPRTRCQKIFQ-------VQAPVNAVMLHPDQSQ-IMVGDQSGIIHIWDLKTDQNE 127
+ + T C F+ VN+V+L P + +V ++S + I +++ Q
Sbjct: 377 NMKT---TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQ-GQIV 432
Query: 128 QLIPEAEASIQDI---AIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAHSKYA 183
+ + D A+ P G+ + V Y +S ++G+ ++ +T H K
Sbjct: 433 RSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKL-----ERTLTVHEKDV 487
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWR 208
+ P ++ T S D K+W+
Sbjct: 488 IGIAHHPHQNLIATYSEDGLLKLWK 512
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/47 (29%), Positives = 25/47 (53%)
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
L R ++ + V A F+ D ++L TGS D + +WN G + ++
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKD 251
>AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec-8
and unc-52 homolog (C. elegans) protein.
Length = 513
Score = 56.4 bits (130), Expect = 1e-07
Identities = 45/174 (25%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 89 FQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ-NEQLIPEAEAS--IQDIAI--- 142
F ++ V PD ++ G G I +W+ T + + L +A+ + + D A+
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 143 --DPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+M+A G VW + SGQ ++ AHSK FS DS+ +++ S
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 200 GDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
D + +I L+E R + +V +A FT D ++ + SSD ++WN++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSS-FVNEATFTQDGHYIISASSDGTVKIWNMK 379
Score = 50.8 bits (116), Expect = 5e-06
Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 9/109 (8%)
Query: 174 KHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR---RDTQRWVWDA 229
+HI K + C +FSPD LVT S D ++W + + ++L+ +D + DA
Sbjct: 207 RHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDA 266
Query: 230 A----FTLDSRFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAF 273
F+ D+ L TG+ D ++W I+ G L R H K +T L+F
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSF 315
Score = 39.5 bits (88), Expect = 0.013
Identities = 46/205 (22%), Positives = 89/205 (43%), Gaps = 24/205 (11%)
Query: 17 TSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIW 75
+S + +A F Q IR++ L S + F S V+ F ++G ++ + D T +IW
Sbjct: 319 SSQILSASFDQTIRIHGLKSGKT--LKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIW 376
Query: 76 DPRAAPRTRCQKIFQ-------VQAPVNAVMLHPDQSQ-IMVGDQSGIIHIWDLKTDQNE 127
+ + T C F+ VN+V+L P + +V ++S + I +++ Q
Sbjct: 377 NMKT---TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQ-GQIV 432
Query: 128 QLIPEAEASIQDI---AIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAHSKYA 183
+ + D A+ P G+ + V Y +S ++G+ ++ +T H K
Sbjct: 433 RSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKL-----ERTLTVHEKDV 487
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWR 208
+ P ++ T S D K+W+
Sbjct: 488 IGIAHHPHQNLIATYSEDGLLKLWK 512
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/47 (29%), Positives = 25/47 (53%)
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
L R ++ + V A F+ D ++L TGS D + +WN G + ++
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKD 251
>AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens
cDNA FLJ10805 fis, clone NT2RP4000839, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 513
Score = 56.4 bits (130), Expect = 1e-07
Identities = 45/174 (25%), Positives = 80/174 (45%), Gaps = 14/174 (8%)
Query: 89 FQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ-NEQLIPEAEAS--IQDIAI--- 142
F ++ V PD ++ G G I +W+ T + + L +A+ + + D A+
Sbjct: 211 FGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCM 270
Query: 143 --DPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTS 199
+M+A G VW + SGQ ++ AHSK FS DS+ +++ S
Sbjct: 271 CFSRDTEMLATGAQDGKIKVWKIQSGQ----CLRRFERAHSKGVTCLSFSKDSSQILSAS 326
Query: 200 GDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
D + +I L+E R + +V +A FT D ++ + SSD ++WN++
Sbjct: 327 FDQTIRIHGLKSGKTLKEFRGHSS-FVNEATFTQDGHYIISASSDGTVKIWNMK 379
Score = 50.8 bits (116), Expect = 5e-06
Identities = 34/109 (31%), Positives = 54/109 (49%), Gaps = 9/109 (8%)
Query: 174 KHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR---RDTQRWVWDA 229
+HI K + C +FSPD LVT S D ++W + + ++L+ +D + DA
Sbjct: 207 RHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDA 266
Query: 230 A----FTLDSRFLFTGSSDSYARLWNIERG-TLEREYCGHQKAITALAF 273
F+ D+ L TG+ D ++W I+ G L R H K +T L+F
Sbjct: 267 VLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSF 315
Score = 37.9 bits (84), Expect = 0.039
Identities = 46/205 (22%), Positives = 88/205 (42%), Gaps = 24/205 (11%)
Query: 17 TSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIW 75
+S + +A F Q IR++ L S + F S V+ F ++G ++ + D T +IW
Sbjct: 319 SSQILSASFDQTIRIHGLKSGKT--LKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIW 376
Query: 76 DPRAAPRTRCQKIFQ-------VQAPVNAVMLHPDQSQ-IMVGDQSGIIHIWDLKTDQNE 127
+ + T C F+ VN+V+L P + +V ++S + I +++ Q
Sbjct: 377 NMKT---TECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQ-GQIV 432
Query: 128 QLIPEAEASIQDI---AIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAHSKYA 183
+ + D A+ P G+ + V Y +S ++G+ ++ +T H K
Sbjct: 433 RSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKL-----ERTLTVHEKDV 487
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWR 208
+ P + T S D K+W+
Sbjct: 488 IGIAHHPHQNPIATYSEDGLLKLWK 512
Score = 32.3 bits (70), Expect = 1.9
Identities = 14/47 (29%), Positives = 25/47 (53%)
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
L R ++ + V A F+ D ++L TGS D + +WN G + ++
Sbjct: 205 LSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKD 251
>AF240696-1|AAF82746.1| 275|Homo sapiens WSB1 isoform 2 protein.
Length = 275
Score = 56.4 bits (130), Expect = 1e-07
Identities = 29/100 (29%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Query: 175 HITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
++ H++ F+PD S +LV+ S D + ++W D + ++ R Q WV+ AF+
Sbjct: 19 NLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP 78
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
DS L + + LWN+++ T+ R+ GH + A F
Sbjct: 79 DSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDF 118
Score = 54.8 bits (126), Expect = 3e-07
Identities = 40/166 (24%), Positives = 67/166 (40%), Gaps = 18/166 (10%)
Query: 102 PDQSQIMVG-DQSGIIHIWDLKTDQNEQLIPEAEAS-IQDIAIDPAGKMMAAVNNKGNCY 159
PD S I+V + + +WDLK D N + + + A P M+ +V +
Sbjct: 34 PDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVF 93
Query: 160 VWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELR 219
+W++ + + +K + H + C FSPD +L T S D IW + +L E
Sbjct: 94 LWNMD---KYTMIRK-LEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFG 149
Query: 220 R------------DTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIE 253
RWV +F+ D + + + D R W I+
Sbjct: 150 HLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRID 195
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/129 (24%), Positives = 54/129 (41%), Gaps = 6/129 (4%)
Query: 137 IQDIAIDPAGKM-MAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTML 195
++D+ P G + + + + VW L K + H + C FSPDS+ML
Sbjct: 27 VRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNM---MKVLRGHQNWVYSCAFSPDSSML 83
Query: 196 VTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERG 255
+ + +W + ++R+L V F+ D L T S D+ +W+ G
Sbjct: 84 CSVGASKAVFLWNMDKYTMIRKL-EGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNG 142
Query: 256 TLEREYCGH 264
+ E+ GH
Sbjct: 143 DILMEF-GH 150
>EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein.
Length = 478
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/243 (18%), Positives = 94/243 (38%), Gaps = 9/243 (3%)
Query: 33 LSSANPDPVTT--FEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ 90
++SA DPV F+ ++ + NG + T D +W+ + P R +
Sbjct: 1 MASATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFK--PHARAYRYVG 58
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
+ V +V P + + + + +W A ++ + G+ +A
Sbjct: 59 HKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLA 118
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTS 210
+ + VWS+ Q + H+ + KFSPD ++V+ S D + KIW T+
Sbjct: 119 TASEDKSIKVWSMYRQRF----LYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTT 174
Query: 211 DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
+ + D+ + F + + SD ++W++ L + Y H +
Sbjct: 175 NKQCVNNF-SDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNC 233
Query: 271 LAF 273
++F
Sbjct: 234 ISF 236
Score = 49.6 bits (113), Expect = 1e-05
Identities = 52/245 (21%), Positives = 96/245 (39%), Gaps = 13/245 (5%)
Query: 9 VNSLEISPTS--MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++ SP + +A+ + +RL+ + F+ + V V F +G ++ T
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGK--FSEFKAHTAPVRSVDFSADGQFLATA 120
Query: 67 GEDCTARIWDPRAAPRTR-CQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
ED + ++W + R R +++ V PD I+ + I IWD Q
Sbjct: 121 SEDKSIKVW---SMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQ 177
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALR 185
++ + +P+G +A+ + VW + +H HS
Sbjct: 178 CVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKL----LQHYQVHSGGVNC 233
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
F P L+T S D + KI + L+ L+ T V+ +F+ +G +D+
Sbjct: 234 ISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGP-VFTVSFSKGGELFASGGADT 292
Query: 246 YARLW 250
LW
Sbjct: 293 QVLLW 297
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/223 (18%), Positives = 85/223 (38%), Gaps = 7/223 (3%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+ V F +G + + D T R+W P R + + APV +V D +
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDK--RGKFSEFKAHTAPVRSVDFSADGQFLATA 120
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ I +W + + + ++ P G+++ + + +W + +
Sbjct: 121 SEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQC-- 178
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAA 230
+ + +A F+P T + + D + K+W LL+ + + V +
Sbjct: 179 --VNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGG-VNCIS 235
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
F +L T SSD ++ ++ G L GH + ++F
Sbjct: 236 FHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSF 278
Score = 36.3 bits (80), Expect = 0.12
Identities = 30/157 (19%), Positives = 58/157 (36%), Gaps = 10/157 (6%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSG 114
F +G + + ED T +IWD +C F N V +P + I
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWD---TTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQ 208
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPK 173
+ +WD++ ++ Q + I+ P+G + ++ G + L G+ +
Sbjct: 209 TVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYT--- 265
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTS 210
+ H+ FS + + D +WRT+
Sbjct: 266 --LQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTN 300
>BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B
protein.
Length = 478
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/243 (18%), Positives = 94/243 (38%), Gaps = 9/243 (3%)
Query: 33 LSSANPDPVTT--FEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ 90
++SA DPV F+ ++ + NG + T D +W+ + P R +
Sbjct: 1 MASATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFK--PHARAYRYVG 58
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
+ V +V P + + + + +W A ++ + G+ +A
Sbjct: 59 HKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLA 118
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTS 210
+ + VWS+ Q + H+ + KFSPD ++V+ S D + KIW T+
Sbjct: 119 TASEDKSIKVWSMYRQRF----LYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTT 174
Query: 211 DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
+ + D+ + F + + SD ++W++ L + Y H +
Sbjct: 175 NKQCVNNF-SDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNC 233
Query: 271 LAF 273
++F
Sbjct: 234 ISF 236
Score = 49.6 bits (113), Expect = 1e-05
Identities = 52/245 (21%), Positives = 96/245 (39%), Gaps = 13/245 (5%)
Query: 9 VNSLEISPTS--MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++ SP + +A+ + +RL+ + F+ + V V F +G ++ T
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGK--FSEFKAHTAPVRSVDFSADGQFLATA 120
Query: 67 GEDCTARIWDPRAAPRTR-CQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
ED + ++W + R R +++ V PD I+ + I IWD Q
Sbjct: 121 SEDKSIKVW---SMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQ 177
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALR 185
++ + +P+G +A+ + VW + +H HS
Sbjct: 178 CVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKL----LQHYQVHSGGVNC 233
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
F P L+T S D + KI + L+ L+ T V+ +F+ +G +D+
Sbjct: 234 ISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGP-VFTVSFSKGGELFASGGADT 292
Query: 246 YARLW 250
LW
Sbjct: 293 QVLLW 297
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/223 (18%), Positives = 85/223 (38%), Gaps = 7/223 (3%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+ V F +G + + D T R+W P R + + APV +V D +
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDK--RGKFSEFKAHTAPVRSVDFSADGQFLATA 120
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ I +W + + + ++ P G+++ + + +W + +
Sbjct: 121 SEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQC-- 178
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAA 230
+ + +A F+P T + + D + K+W LL+ + + V +
Sbjct: 179 --VNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGG-VNCIS 235
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
F +L T SSD ++ ++ G L GH + ++F
Sbjct: 236 FHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSF 278
Score = 36.3 bits (80), Expect = 0.12
Identities = 30/157 (19%), Positives = 58/157 (36%), Gaps = 10/157 (6%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSG 114
F +G + + ED T +IWD +C F N V +P + I
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWD---TTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQ 208
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPK 173
+ +WD++ ++ Q + I+ P+G + ++ G + L G+ +
Sbjct: 209 TVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYT--- 265
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTS 210
+ H+ FS + + D +WRT+
Sbjct: 266 --LQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTN 300
>AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens
cDNA FLJ90291 fis, clone NT2RP1001031, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 478
Score = 56.0 bits (129), Expect = 1e-07
Identities = 46/243 (18%), Positives = 94/243 (38%), Gaps = 9/243 (3%)
Query: 33 LSSANPDPVTT--FEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ 90
++SA DPV F+ ++ + NG + T D +W+ + P R +
Sbjct: 1 MASATEDPVLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFK--PHARAYRYVG 58
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
+ V +V P + + + + +W A ++ + G+ +A
Sbjct: 59 HKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLA 118
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTS 210
+ + VWS+ Q + H+ + KFSPD ++V+ S D + KIW T+
Sbjct: 119 TASEDKSIKVWSMYRQRF----LYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTT 174
Query: 211 DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
+ + D+ + F + + SD ++W++ L + Y H +
Sbjct: 175 NKQCVNNF-SDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNC 233
Query: 271 LAF 273
++F
Sbjct: 234 ISF 236
Score = 49.6 bits (113), Expect = 1e-05
Identities = 52/245 (21%), Positives = 96/245 (39%), Gaps = 13/245 (5%)
Query: 9 VNSLEISPTS--MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++ SP + +A+ + +RL+ + F+ + V V F +G ++ T
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGK--FSEFKAHTAPVRSVDFSADGQFLATA 120
Query: 67 GEDCTARIWDPRAAPRTR-CQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
ED + ++W + R R +++ V PD I+ + I IWD Q
Sbjct: 121 SEDKSIKVW---SMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQ 177
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALR 185
++ + +P+G +A+ + VW + +H HS
Sbjct: 178 CVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKL----LQHYQVHSGGVNC 233
Query: 186 CKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDS 245
F P L+T S D + KI + L+ L+ T V+ +F+ +G +D+
Sbjct: 234 ISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGP-VFTVSFSKGGELFASGGADT 292
Query: 246 YARLW 250
LW
Sbjct: 293 QVLLW 297
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/223 (18%), Positives = 85/223 (38%), Gaps = 7/223 (3%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+ V F +G + + D T R+W P R + + APV +V D +
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDK--RGKFSEFKAHTAPVRSVDFSADGQFLATA 120
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
+ I +W + + + ++ P G+++ + + +W + +
Sbjct: 121 SEDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQC-- 178
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAA 230
+ + +A F+P T + + D + K+W LL+ + + V +
Sbjct: 179 --VNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGG-VNCIS 235
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
F +L T SSD ++ ++ G L GH + ++F
Sbjct: 236 FHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTVSF 278
Score = 36.3 bits (80), Expect = 0.12
Identities = 30/157 (19%), Positives = 58/157 (36%), Gaps = 10/157 (6%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSG 114
F +G + + ED T +IWD +C F N V +P + I
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWD---TTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQ 208
Query: 115 IIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPK 173
+ +WD++ ++ Q + I+ P+G + ++ G + L G+ +
Sbjct: 209 TVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYT--- 265
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTS 210
+ H+ FS + + D +WRT+
Sbjct: 266 --LQGHTGPVFTVSFSKGGELFASGGADTQVLLWRTN 300
>AF145020-1|AAD42075.1| 649|Homo sapiens phospholipase A2
activating protein protein.
Length = 649
Score = 55.2 bits (127), Expect = 2e-07
Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 20/243 (8%)
Query: 9 VNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
+ S +I P ++ G H + LS +P P+ + V + K GT + +G
Sbjct: 17 IPSSDIYPHGLIFTGGNDH-NICILSLDSPMPLYILKGHKNTVCSLSSGKFGT-LLSGSW 74
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQ-APVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
D TA++W +C Q A V AV + P+Q ++ G + +W K + E
Sbjct: 75 DTTAKVW-----LNDKCMMTLQGHTAAVWAVKILPEQGLMLTGSADKTVKLW--KAGRCE 127
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
+ E ++ +AI + ++ N+ + W ++G+ + H+ Y
Sbjct: 128 RTFSGHEDCVRGLAILSETEFLSCAND-ASIRRWQITGEC-----LEVYYGHTNYIYSIS 181
Query: 188 FSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYA 247
P+ VTT+ D S +IW+ + A + +R Q +W LD+ + G+SD
Sbjct: 182 VFPNCRDFVTTAEDRSLRIWKHGECA--QTIRLPAQS-IW-CCCVLDNGDIVVGASDGII 237
Query: 248 RLW 250
R++
Sbjct: 238 RVF 240
Score = 39.9 bits (89), Expect = 0.010
Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 11/131 (8%)
Query: 142 IDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGD 201
I P G + N+ C + SL P+P + H T+L + S D
Sbjct: 22 IYPHGLIFTGGNDHNIC-ILSLDS----PMPLYILKGHKNTVCSLSSGKFGTLL-SGSWD 75
Query: 202 CSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREY 261
+AK+W +D ++ L+ T VW + + TGS+D +LW + G ER +
Sbjct: 76 TTAKVW-LNDKCMMT-LQGHTAA-VWAVKILPEQGLMLTGSADKTVKLW--KAGRCERTF 130
Query: 262 CGHQKAITALA 272
GH+ + LA
Sbjct: 131 SGHEDCVRGLA 141
>BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein.
Length = 351
Score = 54.8 bits (126), Expect = 3e-07
Identities = 46/192 (23%), Positives = 75/192 (39%), Gaps = 11/192 (5%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T RIWD R T+C + + PD I VG++ ++ D KT
Sbjct: 117 TASGDKTIRIWDVRT---TKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTH 173
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
+++ + + + +I+ + M N G + S P P + I AH +
Sbjct: 174 RSKAE-EQFKFEVNEISWNNDNNMFFLTNGNGCINILSY----PELKPVQSINAHPSNCI 228
Query: 185 RCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRW-VWDAAFTLDSRFLFTGSS 243
KF P T S D +W + +R R W V +F+ D + L + S
Sbjct: 229 CIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSR--LDWPVRTLSFSHDGKMLASASE 286
Query: 244 DSYARLWNIERG 255
D + + +E G
Sbjct: 287 DHFIDIAEVETG 298
>BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein.
Length = 351
Score = 54.8 bits (126), Expect = 3e-07
Identities = 46/192 (23%), Positives = 75/192 (39%), Gaps = 11/192 (5%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T RIWD R T+C + + PD I VG++ ++ D KT
Sbjct: 117 TASGDKTIRIWDVRT---TKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTH 173
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
+++ + + + +I+ + M N G + S P P + I AH +
Sbjct: 174 RSKAE-EQFKFEVNEISWNNDNNMFFLTNGNGCINILSY----PELKPVQSINAHPSNCI 228
Query: 185 RCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRW-VWDAAFTLDSRFLFTGSS 243
KF P T S D +W + +R R W V +F+ D + L + S
Sbjct: 229 CIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSR--LDWPVRTLSFSHDGKMLASASE 286
Query: 244 DSYARLWNIERG 255
D + + +E G
Sbjct: 287 DHFIDIAEVETG 298
>AJ005821-1|CAA06718.2| 3027|Homo sapiens X-like 1 protein protein.
Length = 3027
Score = 54.0 bits (124), Expect = 6e-07
Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 4/136 (2%)
Query: 33 LSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR---IWDPRAAPRTRCQKIF 89
++ + P P T++ +K + F + + + T G R +WD AP F
Sbjct: 2823 VTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDXRNVCLWDTLVAPADSLVHAF 2882
Query: 90 QVQAPVNAVMLHPDQSQIMV-GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM 148
V+ + + Q+++ G + G +++DL Q QL ++ ++ +A+DP +
Sbjct: 2883 TCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQLFQSHDSPVKAVAVDPTEEY 2942
Query: 149 MAAVNNKGNCYVWSLS 164
+ +GN +WSLS
Sbjct: 2943 FVTGSAEGNIKIWSLS 2958
Score = 34.3 bits (75), Expect = 0.48
Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 7/115 (6%)
Query: 14 ISPTSMVAAAGF----QHIRLYDLSSANPDP-VTTFEDISKNVSRVGFQKNGTWMYTGGE 68
+S +S++A AG +++ L+D A D V F + + + + +GG
Sbjct: 2847 VSSSSLIATAGLSTDXRNVCLWDTLVAPADSLVHAFTCHDSGATVLAYAPKHQLLISGGR 2906
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKT 123
++D R + Q +PV AV + P + + G G I IW L T
Sbjct: 2907 KGFTYVFD--LCQRQQRQLFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLST 2959
>AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 54.0 bits (124), Expect = 6e-07
Identities = 37/182 (20%), Positives = 75/182 (41%), Gaps = 5/182 (2%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
++PV V+ HP S ++ + I +WD +T E+ + S+QDI+ D +GK++A+
Sbjct: 108 RSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLAS 167
Query: 152 VNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSD 211
+ + G + H H P+ +V+ S D + K+W
Sbjct: 168 CSADMTIKLRDFQGF--ECIRTMH--GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 223
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++ + WV D + + S+D R+W + + E H+ + +
Sbjct: 224 GYCVKTF-TGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECI 282
Query: 272 AF 273
++
Sbjct: 283 SW 284
Score = 39.1 bits (87), Expect = 0.017
Identities = 27/108 (25%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
Query: 165 GQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQR 224
G P P K ++ H R F P +++V+ S D + K+W R L+ T
Sbjct: 93 GWIPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDS 152
Query: 225 WVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALA 272
V D +F + L + S+D +L + + R GH ++++A
Sbjct: 153 -VQDISFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVA 199
Score = 37.1 bits (82), Expect = 0.068
Identities = 49/271 (18%), Positives = 107/271 (39%), Gaps = 21/271 (7%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
MV+A+ I+++D + D T + + +V + F +G + + D T ++ D +
Sbjct: 123 MVSASEDATIKVWDYETG--DFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLRDFQ 180
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
R V++V + P+ I+ + I +W+++T + ++
Sbjct: 181 GFECIRTMHGHDHN--VSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVR 238
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHI--------TAHSKYALRCKFSP 190
+ + G ++A+ +N VW ++ + ++H S Y+ + +
Sbjct: 239 MVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATG 298
Query: 191 DST--------MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGS 242
T L++ S D + K+W S L L WV F +F+ + +
Sbjct: 299 SETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGH-DNWVRGVLFHSGGKFILSCA 357
Query: 243 SDSYARLWNIERGTLEREYCGHQKAITALAF 273
D R+W+ + + H+ +T+L F
Sbjct: 358 DDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 388
Score = 30.7 bits (66), Expect = 5.9
Identities = 19/101 (18%), Positives = 39/101 (38%), Gaps = 4/101 (3%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G + I +WD+ T + + ++ + GK + + + VW +
Sbjct: 311 LLSGSRDKTIKMWDVSTGMCLMTLVGHDNWVRGVLFHSGGKFILSCADDKTLRVWDYKNK 370
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
K + AH + F + +VT S D + K+W
Sbjct: 371 RC----MKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
>AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 53.6 bits (123), Expect = 7e-07
Identities = 46/183 (25%), Positives = 78/183 (42%), Gaps = 9/183 (4%)
Query: 94 PVNAVML--HPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAA 151
PV+A L PD + G G ++I+ +++ + E + I IA P GK +A+
Sbjct: 106 PVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLAS 165
Query: 152 VNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTS 210
G +++++ G+ H + H+ FSPDS +LVT S D KI+
Sbjct: 166 GAIDGIINIFAIATGKLLHT-----LEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQ 220
Query: 211 DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
L L WV + AF D + SSD ++ ++ T + HQ +
Sbjct: 221 HANLAGTLSGHAS-WVLNVAFCPDDTHFVSSSSDKSVKVRDVGTRTCVHTFFDHQDQVWG 279
Query: 271 LAF 273
+ +
Sbjct: 280 VKY 282
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/159 (21%), Positives = 66/159 (41%), Gaps = 7/159 (4%)
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKK 174
I + DL+ + + I +A P + +A + G ++ + SG+ + + +
Sbjct: 88 IRLRDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTR 147
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
K+ L +SPD L + + D I+ + LL L + F+ D
Sbjct: 148 -----GKFILSIAYSPDGKYLASGAIDGIINIFAIATGKLLHTLEGHAMP-IRSLTFSPD 201
Query: 235 SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
S+ L T S D Y ++++++ L GH + +AF
Sbjct: 202 SQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAF 240
Score = 43.2 bits (97), Expect = 0.001
Identities = 41/200 (20%), Positives = 83/200 (41%), Gaps = 10/200 (5%)
Query: 9 VNSLEISPTSMVAAAGF--QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V S++IS T +AA+ HIRL DL N + + + + + F + ++ TG
Sbjct: 67 VVSVDISHTLPIAASSSLDAHIRLRDLE--NGKQIKSIDAGPVDAWTLAFSPDSQYLATG 124
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQN 126
I+ + + + + ++ PD + G GII+I+ + T +
Sbjct: 125 THVGKVNIFGVESGKKE--YSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFAIATGKL 182
Query: 127 EQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRC 186
+ I+ + P +++ ++ G ++ + H ++ H+ + L
Sbjct: 183 LHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQ----HANLAGTLSGHASWVLNV 238
Query: 187 KFSPDSTMLVTTSGDCSAKI 206
F PD T V++S D S K+
Sbjct: 239 AFCPDDTHFVSSSSDKSVKV 258
>DQ641253-1|ABG23317.1| 730|Homo sapiens CDW1 protein.
Length = 730
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD----QNEQLIPEA---------EASIQ 138
Q V V+ + + + G GII +WDL+ + + E + ++ +
Sbjct: 216 QQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYS 275
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ +D G + A N Y+++++G PV + +S + ++ SPD LV+
Sbjct: 276 SLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSG 335
Query: 199 SGDCSAKIWRTS-DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
S D +A IW+ S W L +Q D + T S D+ ++W + RG
Sbjct: 336 SSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE 395
Query: 258 ER 259
E+
Sbjct: 396 EK 397
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V+D A+ L T + D A+ W+++ G L GHQ ++ ++AF
Sbjct: 101 VFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAF 148
Score = 30.7 bits (66), Expect = 5.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
++A N +G +++ Q K AH + P LVT +GD +AK W
Sbjct: 66 VLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFW 125
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLF-TGSSDSYARLWN 251
L+ + Q + AF+ + +F TG D +W+
Sbjct: 126 DVKAGELIGTC-KGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWD 169
>BC033540-1|AAH33540.1| 730|Homo sapiens denticleless homolog
(Drosophila) protein.
Length = 730
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD----QNEQLIPEA---------EASIQ 138
Q V V+ + + + G GII +WDL+ + + E + ++ +
Sbjct: 216 QQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYS 275
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ +D G + A N Y+++++G PV + +S + ++ SPD LV+
Sbjct: 276 SLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSG 335
Query: 199 SGDCSAKIWRTS-DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
S D +A IW+ S W L +Q D + T S D+ ++W + RG
Sbjct: 336 SSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE 395
Query: 258 ER 259
E+
Sbjct: 396 EK 397
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V+D A+ L T + D A+ W+++ G L GHQ ++ ++AF
Sbjct: 101 VFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAF 148
Score = 30.7 bits (66), Expect = 5.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
++A N +G +++ Q K AH + P LVT +GD +AK W
Sbjct: 66 VLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFW 125
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLF-TGSSDSYARLWN 251
L+ + Q + AF+ + +F TG D +W+
Sbjct: 126 DVKAGELIGTC-KGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWD 169
>BC033297-1|AAH33297.1| 730|Homo sapiens denticleless homolog
(Drosophila) protein.
Length = 730
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD----QNEQLIPEA---------EASIQ 138
Q V V+ + + + G GII +WDL+ + + E + ++ +
Sbjct: 216 QQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYS 275
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ +D G + A N Y+++++G PV + +S + ++ SPD LV+
Sbjct: 276 SLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSG 335
Query: 199 SGDCSAKIWRTS-DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
S D +A IW+ S W L +Q D + T S D+ ++W + RG
Sbjct: 336 SSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE 395
Query: 258 ER 259
E+
Sbjct: 396 EK 397
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V+D A+ L T + D A+ W+++ G L GHQ ++ ++AF
Sbjct: 101 VFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAF 148
Score = 30.7 bits (66), Expect = 5.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
++A N +G +++ Q K AH + P LVT +GD +AK W
Sbjct: 66 VLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFW 125
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLF-TGSSDSYARLWN 251
L+ + Q + AF+ + +F TG D +W+
Sbjct: 126 DVKAGELIGTC-KGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWD 169
>AL606468-1|CAH70697.1| 730|Homo sapiens denticleless homolog
(Drosophila) protein.
Length = 730
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD----QNEQLIPEA---------EASIQ 138
Q V V+ + + + G GII +WDL+ + + E + ++ +
Sbjct: 216 QQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYS 275
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ +D G + A N Y+++++G PV + +S + ++ SPD LV+
Sbjct: 276 SLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSG 335
Query: 199 SGDCSAKIWRTS-DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
S D +A IW+ S W L +Q D + T S D+ ++W + RG
Sbjct: 336 SSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE 395
Query: 258 ER 259
E+
Sbjct: 396 EK 397
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V+D A+ L T + D A+ W+++ G L GHQ ++ ++AF
Sbjct: 101 VFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAF 148
Score = 30.7 bits (66), Expect = 5.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
++A N +G +++ Q K AH + P LVT +GD +AK W
Sbjct: 66 VLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFW 125
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLF-TGSSDSYARLWN 251
L+ + Q + AF+ + +F TG D +W+
Sbjct: 126 DVKAGELIGTC-KGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWD 169
>AL592297-1|CAH73803.1| 730|Homo sapiens denticleless homolog
(Drosophila) protein.
Length = 730
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD----QNEQLIPEA---------EASIQ 138
Q V V+ + + + G GII +WDL+ + + E + ++ +
Sbjct: 216 QQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYS 275
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ +D G + A N Y+++++G PV + +S + ++ SPD LV+
Sbjct: 276 SLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSG 335
Query: 199 SGDCSAKIWRTS-DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
S D +A IW+ S W L +Q D + T S D+ ++W + RG
Sbjct: 336 SSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE 395
Query: 258 ER 259
E+
Sbjct: 396 EK 397
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V+D A+ L T + D A+ W+++ G L GHQ ++ ++AF
Sbjct: 101 VFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAF 148
Score = 30.7 bits (66), Expect = 5.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
++A N +G +++ Q K AH + P LVT +GD +AK W
Sbjct: 66 VLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFW 125
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLF-TGSSDSYARLWN 251
L+ + Q + AF+ + +F TG D +W+
Sbjct: 126 DVKAGELIGTC-KGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWD 169
>AK000742-1|BAA91355.1| 730|Homo sapiens protein ( Homo sapiens
cDNA FLJ20735 fis, clone HEP08479. ).
Length = 730
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD----QNEQLIPEA---------EASIQ 138
Q V V+ + + + G GII +WDL+ + + E + ++ +
Sbjct: 216 QQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYS 275
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ +D G + A N Y+++++G PV + +S + ++ SPD LV+
Sbjct: 276 SLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSG 335
Query: 199 SGDCSAKIWRTS-DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
S D +A IW+ S W L +Q D + T S D+ ++W + RG
Sbjct: 336 SSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE 395
Query: 258 ER 259
E+
Sbjct: 396 EK 397
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V+D A+ L T + D A+ W+++ G L GHQ ++ ++AF
Sbjct: 101 VFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAF 148
>AF345896-1|AAK54706.1| 730|Homo sapiens RA-regulated nuclear
matrix-associated protein protein.
Length = 730
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD----QNEQLIPEA---------EASIQ 138
Q V V+ + + + G GII +WDL+ + + E + ++ +
Sbjct: 216 QQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYS 275
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ +D G + A N Y+++++G PV + +S + ++ SPD LV+
Sbjct: 276 SLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSG 335
Query: 199 SGDCSAKIWRTS-DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
S D +A IW+ S W L +Q D + T S D+ ++W + RG
Sbjct: 336 SSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE 395
Query: 258 ER 259
E+
Sbjct: 396 EK 397
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V+D A+ L T + D A+ W+++ G L GHQ ++ ++AF
Sbjct: 101 VFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAF 148
Score = 30.7 bits (66), Expect = 5.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
++A N +G +++ Q K AH + P LVT +GD +AK W
Sbjct: 66 VLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFW 125
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLF-TGSSDSYARLWN 251
L+ + Q + AF+ + +F TG D +W+
Sbjct: 126 DVKAGELIGTC-KGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWD 169
>AF195765-1|AAF35182.1| 730|Homo sapiens L2DTL protein protein.
Length = 730
Score = 53.2 bits (122), Expect = 1e-06
Identities = 42/182 (23%), Positives = 77/182 (42%), Gaps = 14/182 (7%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD----QNEQLIPEA---------EASIQ 138
Q V V+ + + + G GII +WDL+ + + E + ++ +
Sbjct: 216 QQSVTVVLFQDENTLVSAGAVDGIIKVWDLRKNYTAYRQEPIASKSFLYPGSSTRKLGYS 275
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ +D G + A N Y+++++G PV + +S + ++ SPD LV+
Sbjct: 276 SLILDSTGSTLFANCTDDNIYMFNMTGLKTSPVAIFNGHQNSTFYVKSSLSPDDQFLVSG 335
Query: 199 SGDCSAKIWRTS-DWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
S D +A IW+ S W L +Q D + T S D+ ++W + RG
Sbjct: 336 SSDEAAYIWKVSTPWQPPTVLLGHSQEVTSVCWCPSDFTKIATCSDDNTLKIWRLNRGLE 395
Query: 258 ER 259
E+
Sbjct: 396 EK 397
Score = 31.5 bits (68), Expect = 3.4
Identities = 15/48 (31%), Positives = 26/48 (54%)
Query: 226 VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
V+D A+ L T + D A+ W+++ G L GHQ ++ ++AF
Sbjct: 101 VFDLAWVPGELKLVTAAGDQTAKFWDVKAGELIGTCKGHQCSLKSVAF 148
Score = 30.7 bits (66), Expect = 5.9
Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 2/105 (1%)
Query: 148 MMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
++A N +G +++ Q K AH + P LVT +GD +AK W
Sbjct: 66 VLAVANEEGFVRLYNTESQSFRKKCFKEWMAHWNAVFDLAWVPGELKLVTAAGDQTAKFW 125
Query: 208 RTSDWALLRELRRDTQRWVWDAAFTLDSRFLF-TGSSDSYARLWN 251
L+ + Q + AF+ + +F TG D +W+
Sbjct: 126 DVKAGELIGTC-KGHQCSLKSVAFSKFEKAVFCTGGRDGNIMVWD 169
>AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal
transducing proteins GS/GI protein.
Length = 207
Score = 52.4 bits (120), Expect = 2e-06
Identities = 26/100 (26%), Positives = 47/100 (47%), Gaps = 2/100 (2%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
+ + H+ Y C+F D+ +VT+SGD + +W T V +
Sbjct: 4 RELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQQTTTFTGHTGD-VMSLSLAP 61
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D+R +G+ D+ A+LW++ G + + GH+ I A+ F
Sbjct: 62 DTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICF 101
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 19 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 76
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 77 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 133
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 134 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 189
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 190 DGMAVATGSWDSFLKIW 206
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 20 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 79
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 80 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 135
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 136 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 189
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 26 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 83
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 84 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 136
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 137 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 195
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 196 TGSWDSFLKIWN 207
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 96 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 155
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 156 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 207
>AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens
cDNA FLJ45988 fis, clone PUAEN2006639, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 369
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/225 (20%), Positives = 85/225 (37%), Gaps = 10/225 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLH-PDQSQIMV 109
++ V K+G+ TG D T ++WD +A + + V A+ + P +I
Sbjct: 95 LTNVALNKSGSCFITGSYDRTCKLWD--SASGEELNTLEGHRNVVYAIAFNNPYGDKIAT 152
Query: 110 GDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPP 168
G +W ++T + A I ++ +P ++A + +W + +G+
Sbjct: 153 GSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV 212
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
+ + HS + F+ ++T S D + +W + L +
Sbjct: 213 YT-----LRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAE-ISS 266
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
A+F D + TGS D +LW+ G GH I F
Sbjct: 267 ASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCF 311
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/148 (22%), Positives = 60/148 (40%), Gaps = 6/148 (4%)
Query: 8 QVNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYT 65
++ L +P S + A G +L+D+ N + V T S + + F +G + T
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQ--NGEEVYTLRGHSAEIISLSFNTSGDRIIT 236
Query: 66 GGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQ 125
G D T +WD A + + A +++ + D S I+ G +WD +
Sbjct: 237 GSFDHTVVVWD--ADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGK 294
Query: 126 NEQLIPEAEASIQDIAIDPAGKMMAAVN 153
+ + I D D GK++A +
Sbjct: 295 CVATLTGHDDEILDSCFDYTGKLIATAS 322
Score = 37.9 bits (84), Expect = 0.039
Identities = 27/104 (25%), Positives = 43/104 (41%), Gaps = 2/104 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K + AH + + +T S D + K+W ++ L L + V+ AF
Sbjct: 86 KVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGH-RNVVYAIAFNN 144
Query: 234 D-SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
+ TGS D +LW++E G + GH I L+F Q
Sbjct: 145 PYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQ 188
Score = 33.9 bits (74), Expect = 0.63
Identities = 31/174 (17%), Positives = 62/174 (35%), Gaps = 6/174 (3%)
Query: 43 TFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHP 102
TF + + + F T + TG D TA++WD + + A + ++ +
Sbjct: 172 TFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV--YTLRGHSAEIISLSFNT 229
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
+I+ G + +WD T + ++ A I + + ++ + C +W
Sbjct: 230 SGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWD 289
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLR 216
+ +T H L F ++ T S D + R A+ R
Sbjct: 290 ATNGKCVAT----LTGHDDEILDSCFDYTGKLIATASADDGVSLCRPGRSAVAR 339
>AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor
protein.
Length = 310
Score = 51.6 bits (118), Expect = 3e-06
Identities = 35/150 (23%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
TG +D T ++WD R + + FQ V AV + QI+ G I +WDL+ +
Sbjct: 110 TGSDDGTVKLWDIR---KKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQN 166
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP----VPKKHITAHS 180
+ + S+ +++ G + + VW + P + + ++
Sbjct: 167 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFE 226
Query: 181 KYALRCKFSPDSTMLVTTSGDCSAKIWRTS 210
K LRC +SPD + + S D +W T+
Sbjct: 227 KNLLRCSWSPDGSKIAAGSADRFVYVWDTT 256
Score = 42.7 bits (96), Expect = 0.001
Identities = 37/188 (19%), Positives = 76/188 (40%), Gaps = 10/188 (5%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD-QNEQLIPEAEASIQDIAIDPAGKMMA 150
+ V HP+ S + +I +W++ D N + ++ ++ + G M+
Sbjct: 7 EGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLF 66
Query: 151 AVNNKGNCYVW-SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT-SGDCSAKIWR 208
+ + VW S +G+ K + H+ + C + LV T S D + K+W
Sbjct: 67 SASTDKTVAVWDSETGERV-----KRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 121
Query: 209 TSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
A ++ + Q V F S + +G D+ ++W++ + L GH ++
Sbjct: 122 IRKKAAVQTFQNTYQ--VLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSV 179
Query: 269 TALAFKDQ 276
T L+ +
Sbjct: 180 TGLSLSSE 187
Score = 34.3 bits (75), Expect = 0.48
Identities = 21/96 (21%), Positives = 38/96 (39%), Gaps = 2/96 (2%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLD 234
++ H CKF P+ + L + D +W D L+ + V + + D
Sbjct: 3 LSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGA-VMELHYNTD 61
Query: 235 SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITA 270
LF+ S+D +W+ E G + GH + +
Sbjct: 62 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNS 97
>AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3
variant protein.
Length = 832
Score = 50.4 bits (115), Expect = 7e-06
Identities = 44/203 (21%), Positives = 78/203 (38%), Gaps = 18/203 (8%)
Query: 61 TWMYTGGEDCTARIWD-PRA-APRTRCQK----IFQVQA-------PVNAVMLHPDQSQI 107
+++ TG +DCT ++W P+A P+ + Q Q +N+V + P+ +
Sbjct: 459 SFLVTGSQDCTVKLWPLPKALLPKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKLL 518
Query: 108 MVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQP 167
G Q +W L Q + + + P +++A + G +W+L
Sbjct: 519 ATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFS 578
Query: 168 PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVW 227
K H L+ F T L+++ D K+W + +R L + VW
Sbjct: 579 ----CLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAHEDK-VW 633
Query: 228 DAAFTLDSRFLFTGSSDSYARLW 250
+ TG+SDS LW
Sbjct: 634 GLHCSRLDDHALTGASDSRVILW 656
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Query: 179 HSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
H K +P+ +L T S D +AK+W LL +R +W F+ + L
Sbjct: 502 HDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGH-RRGLWCVQFSPMDQVL 560
Query: 239 FTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
T S+D +LW ++ + + + GH ++ +AF
Sbjct: 561 ATASADGTIKLWALQDFSCLKTFEGHDASVLKVAF 595
Score = 40.7 bits (91), Expect = 0.005
Identities = 34/170 (20%), Positives = 66/170 (38%), Gaps = 6/170 (3%)
Query: 7 EQVNSLEISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDI-SKNVSRVGFQKNGTWMYT 65
E + + ++SP + V + + L + ++ I + V+ + F T + T
Sbjct: 91 EDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLAT 150
Query: 66 GGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQS--GIIHIWDLKT 123
GG D R+WD V+ V HPD +++++ + I +W L+
Sbjct: 151 GGCDGAVRVWD--IVRHYGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWSLQD 208
Query: 124 DQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVP 172
++ +++ +A G M + C +W L S Q VP
Sbjct: 209 RSCLAVLTAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVP 258
Score = 39.5 bits (88), Expect = 0.013
Identities = 36/190 (18%), Positives = 69/190 (36%), Gaps = 8/190 (4%)
Query: 92 QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAE-ASIQDIAIDPAGKMMA 150
Q + A L PD ++ ++ ++ W + +L A + +A DP ++A
Sbjct: 90 QEDITAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLA 149
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDST--MLVTTSGDCSAKIWR 208
G VW + H F PD T +L +++ D + ++W
Sbjct: 150 TGGCDGAVRVWDIVRH----YGTHHFRGSPGVVHLVAFHPDPTRLLLFSSATDAAIRVWS 205
Query: 209 TSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
D + L L V AF+ D + + D +W+++ R +
Sbjct: 206 LQDRSCLAVLTAHYSA-VTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFESVE 264
Query: 269 TALAFKDQPV 278
A+ ++PV
Sbjct: 265 AAVLLPEEPV 274
Score = 36.7 bits (81), Expect = 0.089
Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 4/123 (3%)
Query: 42 TTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQ-VQAPVNAVML 100
TT K+++ V N + TG +D TA++W A P+ + +F + + V
Sbjct: 497 TTQRCHDKDINSVAIAPNDKLLATGSQDRTAKLW---ALPQCQLLGVFSGHRRGLWCVQF 553
Query: 101 HPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV 160
P + G I +W L+ + +AS+ +A G + + + G +
Sbjct: 554 SPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKL 613
Query: 161 WSL 163
W++
Sbjct: 614 WTI 616
Score = 31.1 bits (67), Expect = 4.4
Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V+ + F +G M + G D IWD ++ TR +F+ V A +L P++ +G
Sbjct: 222 VTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFE---SVEAAVLLPEEPVSQLG 278
Query: 111 DQS 113
+S
Sbjct: 279 VKS 281
>AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide
binding protein (G protein), beta polypeptide 1 protein.
Length = 197
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/197 (20%), Positives = 76/197 (38%), Gaps = 12/197 (6%)
Query: 14 ISPTSMVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
+ +V ++G L+D+ + TTF + +V + + +G D +A+
Sbjct: 9 LDDNQIVTSSGDTTCALWDIETGQQ--TTTFTGHTGDVMSLSLAPDTRLFVSGACDASAK 66
Query: 74 IWDPRAAPRTRCQKIFQ-VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
+WD R C++ F ++ +NA+ P+ + G ++DL+ DQ
Sbjct: 67 LWDVREG---MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSH 123
Query: 133 AE--ASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
I ++ +G+++ A + NC VW V + H +
Sbjct: 124 DNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGV----LAGHDNRVSCLGVTD 179
Query: 191 DSTMLVTTSGDCSAKIW 207
D + T S D KIW
Sbjct: 180 DGMAVATGSWDSFLKIW 196
Score = 48.0 bits (109), Expect = 4e-05
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 182 YALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTG 241
Y C+F D+ +VT+SGD + +W T V + D+R +G
Sbjct: 2 YLSCCRFLDDN-QIVTSSGDTTCALWDIETGQQTTTFTGHTGD-VMSLSLAPDTRLFVSG 59
Query: 242 SSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D+ A+LW++ G + + GH+ I A+ F
Sbjct: 60 ACDASAKLWDVREGMCRQTFTGHESDINAICF 91
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/174 (16%), Positives = 62/174 (35%), Gaps = 5/174 (2%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +QI+ +WD++T Q + +++ P ++ + + +W
Sbjct: 10 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 69
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRD 221
+ + ++ T H F P+ T S D + +++ +D L+ +
Sbjct: 70 VR----EGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDN 125
Query: 222 TQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ +F+ R L G D +W+ + GH ++ L D
Sbjct: 126 IICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 179
Score = 38.3 bits (85), Expect = 0.029
Identities = 41/192 (21%), Positives = 66/192 (34%), Gaps = 15/192 (7%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
T D T +WD +T V ++ L PD + G +WD++
Sbjct: 16 TSSGDTTCALWDIETGQQTTT--FTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREG 73
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYAL 184
Q E+ I I P G A ++ C ++ L + + +S +
Sbjct: 74 MCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRAD-------QELMTYSHDNI 126
Query: 185 RC-----KFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLF 239
C FS +L+ D + +W L R V T D +
Sbjct: 127 ICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNR-VSCLGVTDDGMAVA 185
Query: 240 TGSSDSYARLWN 251
TGS DS+ ++WN
Sbjct: 186 TGSWDSFLKIWN 197
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/114 (21%), Positives = 45/114 (39%), Gaps = 4/114 (3%)
Query: 9 VNSLEISPTSMVAAAGFQHI--RLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
+N++ P A G RL+DL + + ++I ++ V F K+G + G
Sbjct: 86 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAG 145
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWD 120
+D +WD A R + V+ + + D + G + IW+
Sbjct: 146 YDDFNCNVWD--ALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN 197
>AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease
activating factor-1 protein.
Length = 1171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 44/178 (24%), Positives = 75/178 (42%), Gaps = 17/178 (9%)
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPA 145
Q FQ + V + D+ ++ I +W+ + D+ L E +++D +
Sbjct: 962 QSRFQHKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCIFLRGHQE-TVKDFRLLKN 1020
Query: 146 GKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSA 204
++++ + G VW++ +G +K H L C S D+T +TS D +A
Sbjct: 1021 SRLLSW-SFDGTVKVWNIITGNK-----EKDFVCHQGTVLSCDISHDATKFSSTSADKTA 1074
Query: 205 KIWRTSDWALL-------RELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERG 255
KIW S+ LL E WV D F+ D + L S+ Y + WN+ G
Sbjct: 1075 KIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLI--SAGGYIKWWNVVTG 1130
Score = 48.8 bits (111), Expect = 2e-05
Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 5/107 (4%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
I AH L C FS D + T S D KIW + L+ +++ V FT S
Sbjct: 661 IKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQ-VNCCHFTNSS 719
Query: 236 RFLF--TGSSDSYARLWNIERGTLEREYCGHQKAITALAFK--DQPV 278
L TGSSD + +LW++ + GH ++ F D+P+
Sbjct: 720 HHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKPL 766
Score = 46.8 bits (106), Expect = 8e-05
Identities = 48/219 (21%), Positives = 94/219 (42%), Gaps = 16/219 (7%)
Query: 51 VSRVGFQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V V F +G+ T +D T R+W+ + + + Q V+ V+ ++ ++
Sbjct: 850 VHGVMFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ---EVD-VVFQENEVMVLAV 905
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHP 170
D + + + +T Q + L EA + + P + +A + G + L +
Sbjct: 906 DHIRRLQLINGRTGQIDYL---TEAQVSCCCLSPHLQYIAFGDENGAIEILELVN---NR 959
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLREL-RRDTQRWVWDA 229
+ + H K +F+ D L+++S D ++W +W L + + R Q V D
Sbjct: 960 IFQSRFQ-HKKTVWHIQFTADEKTLISSSDDAEIQVW---NWQLDKCIFLRGHQETVKDF 1015
Query: 230 AFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAI 268
+SR L + S D ++WNI G E+++ HQ +
Sbjct: 1016 RLLKNSRLL-SWSFDGTVKVWNIITGNKEKDFVCHQGTV 1053
Score = 40.7 bits (91), Expect = 0.005
Identities = 23/98 (23%), Positives = 40/98 (40%), Gaps = 1/98 (1%)
Query: 176 ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDS 235
+ H+ FS D + + D + ++++ L E++ V AF+ D
Sbjct: 619 VRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDE-VLCCAFSTDD 677
Query: 236 RFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
RF+ T S D ++WN G L Y H + + F
Sbjct: 678 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHF 715
Score = 39.9 bits (89), Expect = 0.010
Identities = 44/193 (22%), Positives = 72/193 (37%), Gaps = 26/193 (13%)
Query: 34 SSANPDPVTTFEDISKNVSRVGFQKNGTWMY--TGGEDCTARIWDPRAAPRTRCQK-IFQ 90
+S + V T+++ S+ V+ F + + TG DC ++WD + C+ +F
Sbjct: 693 NSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLN---QKECRNTMFG 749
Query: 91 VQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMA 150
VN PD + G + +WD T NE+ + ++ DP M
Sbjct: 750 HTNSVNHCRFSPDDKPLASCSADGTLKLWDA-TSANERKSINVKQFFLNLE-DPQEDMEV 807
Query: 151 AVNNKGNCYVWSLSGQPPHPVPKKHI--------------TAHSKYALRCKFSPDSTMLV 196
V C WS G K I H + FSPD + +
Sbjct: 808 IVK----CCSWSADGARIMVAAKNKIFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFL 863
Query: 197 TTSGDCSAKIWRT 209
T+S D + ++W T
Sbjct: 864 TSSDDQTIRLWET 876
Score = 31.1 bits (67), Expect = 4.4
Identities = 28/157 (17%), Positives = 60/157 (38%), Gaps = 14/157 (8%)
Query: 56 FQKNGTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVM---LHPDQSQIMVGDQ 112
F ++G + + G D T +++ +K+ +++A + V+ D I
Sbjct: 631 FSEDGQRIASCGADKTLQVFKAETG-----EKLLEIKAHEDEVLCCAFSTDDRFIATCSV 685
Query: 113 SGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYV--WSLSGQPPHP 170
+ IW+ T + E + + + +C++ W L+ +
Sbjct: 686 DKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC-- 743
Query: 171 VPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ + H+ C+FSPD L + S D + K+W
Sbjct: 744 --RNTMFGHTNSVNHCRFSPDDKPLASCSADGTLKLW 778
Score = 30.7 bits (66), Expect = 5.9
Identities = 34/169 (20%), Positives = 69/169 (40%), Gaps = 7/169 (4%)
Query: 89 FQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKM 148
+ +A V+ L P I GD++G I I +L ++ Q + + ++ I K
Sbjct: 923 YLTEAQVSCCCLSPHLQYIAFGDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKT 982
Query: 149 MAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWR 208
+ + ++ VW+ Q + + H + + +S +L + S D + K+W
Sbjct: 983 LISSSDDAEIQVWNW--QLDKCI---FLRGHQETVKDFRLLKNSRLL-SWSFDGTVKVWN 1036
Query: 209 TSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL 257
++ Q V + D+ + S+D A++WN+ G L
Sbjct: 1037 IITGNKEKDFVCH-QGTVLSCDISHDATKFSSTSADKTAKIWNVSNGEL 1084
>M99438-1|AAA61194.1| 772|Homo sapiens transducin-like enhancer
protein protein.
Length = 772
Score = 49.2 bits (112), Expect = 2e-05
Identities = 39/150 (26%), Positives = 62/150 (41%), Gaps = 10/150 (6%)
Query: 63 MYTGGEDCTARIWD---PRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIW 119
+YTGG+ C +IWD P + + + LHPD ++VG + + IW
Sbjct: 501 VYTGGKGCV-KIWDISQPGSKSPISQLDCLNRDNYMRSCKLHPDGRTLIVGGEGSTLTIW 559
Query: 120 DL--KTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHIT 177
DL T + + + + + +AI P K+ + + GN VW L Q +
Sbjct: 560 DLASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQ----TLVRQFQ 615
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIW 207
H+ A S D T L T D + + W
Sbjct: 616 GHTDGASCIDISHDGTKLWTGGLDNTVRSW 645
Score = 43.6 bits (98), Expect = 8e-04
Identities = 34/166 (20%), Positives = 66/166 (39%), Gaps = 9/166 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQD-----IAIDPAGKMM 149
V AV + + G + G + IWD+ ++ I + + +D + P G+ +
Sbjct: 489 VCAVTISNPSRHVYTGGK-GCVKIWDISQPGSKSPISQLDCLNRDNYMRSCKLHPDGRTL 547
Query: 150 AAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT 209
+W L+ P P K +T+ + SPD+ + + D + +W
Sbjct: 548 IVGGEGSTLTIWDLAS--PTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 605
Query: 210 SDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERG 255
+ L+R+ + T + D L+TG D+ R W++ G
Sbjct: 606 HNQTLVRQFQGHTD-GASCIDISHDGTKLWTGGLDNTVRSWDLREG 650
Score = 42.3 bits (95), Expect = 0.002
Identities = 48/199 (24%), Positives = 80/199 (40%), Gaps = 13/199 (6%)
Query: 11 SLEISPTSMV--AAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
+L ISP + V + +I ++DL N V F+ + S + +GT ++TGG
Sbjct: 581 ALAISPDAKVCFSCCSDGNIAVWDLH--NQTLVRQFQGHTDGASCIDISHDGTKLWTGGL 638
Query: 69 DCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQ 128
D T R WD R R Q F Q + ++ P + VG +S + + T ++
Sbjct: 639 DNTVRSWDLREG-RQLQQHDFTSQ--IFSLGYCPTGEWLAVGMESSNVEVLH-HTKPHKY 694
Query: 129 LIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKF 188
+ E+ + + GK + W + P+ + S L C
Sbjct: 695 QLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAW----RTPYGASISQ-SKESSSVLSCDI 749
Query: 189 SPDSTMLVTTSGDCSAKIW 207
S D +VT SGD A ++
Sbjct: 750 SADDKYIVTGSGDKKATVY 768
Score = 41.9 bits (94), Expect = 0.002
Identities = 34/150 (22%), Positives = 59/150 (39%), Gaps = 8/150 (5%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D +++ G + WDL+ + Q + + I + P G+ +A N V
Sbjct: 629 DGTKLWTGGLDNTVRSWDLREGRQLQQ-HDFTSQIFSLGYCPTGEWLAVGMESSNVEV-- 685
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
L PH K + H L KF+ V+T D WRT A + + + +
Sbjct: 686 LHHTKPH---KYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASISQSKESS 742
Query: 223 QRWVWDAAFTLDSRFLFTGSSDSYARLWNI 252
V + D +++ TGS D A ++ +
Sbjct: 743 S--VLSCDISADDKYIVTGSGDKKATVYEV 770
Score = 40.3 bits (90), Expect = 0.007
Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 4/113 (3%)
Query: 155 KGNCYVWSLSGQP--PHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWR-TSD 211
KG +W +S QP P+ + Y CK PD L+ + IW S
Sbjct: 506 KGCVKIWDIS-QPGSKSPISQLDCLNRDNYMRSCKLHPDGRTLIVGGEGSTLTIWDLASP 564
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGH 264
++ + + A + D++ F+ SD +W++ TL R++ GH
Sbjct: 565 TPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDLHNQTLVRQFQGH 617
Score = 38.3 bits (85), Expect = 0.029
Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
Query: 15 SPTSMVAAAGFQHIRLYDLSS-ANPDPVTTFEDISKN--VSRVGFQKNGTWMYTGGEDCT 71
+P+ V G ++++D+S + P++ + ++++ + +G + GGE T
Sbjct: 496 NPSRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDNYMRSCKLHPDGRTLIVGGEGST 555
Query: 72 ARIWDPRAAPRTRCQKIFQVQAPV-NAVMLHPDQSQIMVGDQSGIIHIWDL 121
IWD A+P R + AP A+ + PD G I +WDL
Sbjct: 556 LTIWD-LASPTPRIKAELTSSAPACYALAISPDAKVCFSCCSDGNIAVWDL 605
>M99436-1|AAA61193.1| 743|Homo sapiens transducin-like enhancer
protein protein.
Length = 743
Score = 49.2 bits (112), Expect = 2e-05
Identities = 45/216 (20%), Positives = 86/216 (39%), Gaps = 13/216 (6%)
Query: 63 MYTGGEDCTARIWD---PRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIW 119
+YTGG+ C ++WD P A R + + L PD ++VG ++ + IW
Sbjct: 472 VYTGGKGCV-KVWDVGQPGAKTPVRQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIW 530
Query: 120 DL--KTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHIT 177
DL T + + + + + +A+ P K+ + + GN VW L Q +
Sbjct: 531 DLAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQ----TMVRQFQ 586
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRF 237
H+ A S T L T D + + W + L++ D ++ + +
Sbjct: 587 GHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQ--HDFSSQIFSPCHCPNQDW 644
Query: 238 LFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L G S + ++ + + + H+ + +L F
Sbjct: 645 LAVGMESSNVEILHVGKPEKYQLHL-HESCVLSLKF 679
Score = 46.0 bits (104), Expect = 1e-04
Identities = 47/200 (23%), Positives = 83/200 (41%), Gaps = 15/200 (7%)
Query: 11 SLEISPTSMV--AAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGE 68
+L +SP + V + +I ++DL N V F+ + S + GT ++TGG
Sbjct: 552 ALAVSPDAKVCFSCCSDGNIVVWDLQ--NQTMVRQFQGHTDGASCIDISDYGTRLWTGGL 609
Query: 69 DCTARIWDPRAAPRTRCQKI-FQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE 127
D T R WD R + + Q+ +P + P+Q + VG +S + I + +
Sbjct: 610 DNTVRCWDLREGRQLQQHDFSSQIFSPCHC----PNQDWLAVGMESSNVEILHVGKPEKY 665
Query: 128 QLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCK 187
QL E+ + + P G+ + W + P+ + S L C
Sbjct: 666 QLHLH-ESCVLSLKFAPCGRWFVSTGKDNLLNAW----RTPYGA-SIFQSKESSSVLSCD 719
Query: 188 FSPDSTMLVTTSGDCSAKIW 207
S ++ +VT SGD A ++
Sbjct: 720 ISRNNKYIVTGSGDKKATVY 739
Score = 40.7 bits (91), Expect = 0.005
Identities = 27/124 (21%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSK--YALRCKFSPDSTMLVTTSGDCSAKIWR-TSD 211
KG VW + GQP P + + ++ Y CK PD L+ + IW +
Sbjct: 477 KGCVKVWDV-GQPGAKTPVRQLDCLNRDNYIRSCKLLPDGRSLIVGGEASTLSIWDLAAP 535
Query: 212 WALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
++ + + A + D++ F+ SD +W+++ T+ R++ GH + +
Sbjct: 536 TPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQTMVRQFQGHTDGASCI 595
Query: 272 AFKD 275
D
Sbjct: 596 DISD 599
Score = 33.9 bits (74), Expect = 0.63
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 9/129 (6%)
Query: 7 EQVNSLEIS-PTSMVAAAGFQHIRLYDLSSANPD-PVTTFEDISKN--VSRVGFQKNGTW 62
E V ++ IS T V G ++++D+ PV + ++++ + +G
Sbjct: 458 EVVCAVTISGSTQHVYTGGKGCVKVWDVGQPGAKTPVRQLDCLNRDNYIRSCKLLPDGRS 517
Query: 63 MYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPV-NAVMLHPDQSQIMVGDQSGIIHIWDL 121
+ GGE T IWD AAP R + AP A+ + PD G I +WDL
Sbjct: 518 LIVGGEASTLSIWD-LAAPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDL 576
Query: 122 KTDQNEQLI 130
QN+ ++
Sbjct: 577 ---QNQTMV 582
Score = 33.5 bits (73), Expect = 0.83
Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 3/82 (3%)
Query: 172 PKKH-ITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAA 230
P+K+ + H L KF+P V+T D WRT A + + + + V
Sbjct: 662 PEKYQLHLHESCVLSLKFAPCGRWFVSTGKDNLLNAWRTPYGASIFQSKESSS--VLSCD 719
Query: 231 FTLDSRFLFTGSSDSYARLWNI 252
+ +++++ TGS D A ++ +
Sbjct: 720 ISRNNKYIVTGSGDKKATVYEV 741
>EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related
16-like protein 1 protein.
Length = 444
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 301 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 357
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 358 AIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 417
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 418 NAVA----WSPSGSHVVSVDKGCKAVLW 441
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 10/168 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE--QLIPEAEASIQDIAIDPAGKMMAAV 152
VNAV P + G + +W++ ++ E + + A I I D AG + A
Sbjct: 162 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 221
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+N +W++ + +T HS L KF D+ +V+ S D + K+W
Sbjct: 222 SNDFASRIWTVDDYRL----RHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 277
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
++ + + D T + + +G D R W+I ++ RE
Sbjct: 278 VCIKTVFAGSS--CNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVRE 321
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 308 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 364
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 365 APGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 424
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 425 SGSHVVSVDKGCKAVLWA 442
Score = 34.7 bits (76), Expect = 0.36
Identities = 21/97 (21%), Positives = 36/97 (37%), Gaps = 1/97 (1%)
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLDSR 236
AH +FSP S +L T D K+W + + + + F
Sbjct: 157 AHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS 216
Query: 237 FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+L S+D +R+W ++ L GH + + F
Sbjct: 217 YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKF 253
>EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related
16-like protein 1 protein.
Length = 588
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 445 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 501
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 502 AIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 561
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 562 NAVA----WSPSGSHVVSVDKGCKAVLW 585
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 10/168 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE--QLIPEAEASIQDIAIDPAGKMMAAV 152
VNAV P + G + +W++ ++ E + + A I I D AG + A
Sbjct: 306 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 365
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+N +W++ + +T HS L KF D+ +V+ S D + K+W
Sbjct: 366 SNDFASRIWTVDDYRL----RHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 421
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
++ + + D T + + +G D R W+I ++ RE
Sbjct: 422 VCIKTVFAGSS--CNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVRE 465
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 452 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 508
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 509 APGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 568
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 569 SGSHVVSVDKGCKAVLWA 586
Score = 34.7 bits (76), Expect = 0.36
Identities = 21/97 (21%), Positives = 36/97 (37%), Gaps = 1/97 (1%)
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLDSR 236
AH +FSP S +L T D K+W + + + + F
Sbjct: 301 AHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS 360
Query: 237 FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+L S+D +R+W ++ L GH + + F
Sbjct: 361 YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKF 397
>BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein.
Length = 523
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 380 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 436
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 437 AIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 496
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 497 NAVA----WSPSGSHVVSVDKGCKAVLW 520
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 10/168 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE--QLIPEAEASIQDIAIDPAGKMMAAV 152
VNAV P + G + +W++ ++ E + + A I I D AG + A
Sbjct: 241 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 300
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+N +W++ + +T HS L KF D+ +V+ S D + K+W
Sbjct: 301 SNDFASRIWTVDDYRL----RHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 356
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
++ + + D T + + +G D R W+I ++ RE
Sbjct: 357 VCIKTVFAGSS--CNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVRE 400
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 387 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 443
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 444 APGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 503
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 504 SGSHVVSVDKGCKAVLWA 521
Score = 34.7 bits (76), Expect = 0.36
Identities = 21/97 (21%), Positives = 36/97 (37%), Gaps = 1/97 (1%)
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLDSR 236
AH +FSP S +L T D K+W + + + + F
Sbjct: 236 AHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS 295
Query: 237 FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+L S+D +R+W ++ L GH + + F
Sbjct: 296 YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKF 332
>BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein.
Length = 475
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 332 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 388
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 389 AIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 448
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 449 NAVA----WSPSGSHVVSVDKGCKAVLW 472
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 10/168 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE--QLIPEAEASIQDIAIDPAGKMMAAV 152
VNAV P + G + +W++ ++ E + + A I I D AG + A
Sbjct: 193 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 252
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+N +W++ + +T HS L KF D+ +V+ S D + K+W
Sbjct: 253 SNDFASRIWTVDDYRL----RHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 308
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
++ + + D T + + +G D R W+I ++ RE
Sbjct: 309 VCIKTVFAGSS--CNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVRE 352
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 339 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 395
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 396 APGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 455
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 456 SGSHVVSVDKGCKAVLWA 473
Score = 34.7 bits (76), Expect = 0.36
Identities = 21/97 (21%), Positives = 36/97 (37%), Gaps = 1/97 (1%)
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLDSR 236
AH +FSP S +L T D K+W + + + + F
Sbjct: 188 AHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS 247
Query: 237 FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+L S+D +R+W ++ L GH + + F
Sbjct: 248 YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKF 284
>BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 48.8 bits (111), Expect = 2e-05
Identities = 35/161 (21%), Positives = 69/161 (42%), Gaps = 5/161 (3%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V +V+ HP Q + I IW + Q++ E+++ +++ G + +++
Sbjct: 267 VTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYL--LSS 324
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ Y W+ S V K S +L C +F PD + T + D KIW +
Sbjct: 325 SDDQY-WAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERT 383
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
+ + + AF+ + +L T + DS +LW++ +
Sbjct: 384 NVANFPGHSGP-ITSIAFSENGYYLATAADDSSVKLWDLRK 423
Score = 44.4 bits (100), Expect = 4e-04
Identities = 50/263 (19%), Positives = 99/263 (37%), Gaps = 15/263 (5%)
Query: 15 SPTSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
S T+ + G +++ ++D SS + T + +K V+ V F + +++ D T R
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQI--LATLKGHTKKVTSVVFHPSQDLVFSASPDATIR 289
Query: 74 IWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
IW + P C ++ + ++ V + LH ++ D++T + + +
Sbjct: 290 IW---SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
Query: 133 AEA--SIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
+ S+ P G + +W L + + HS FS
Sbjct: 347 ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKER----TNVANFPGHSGPITSIAFSE 402
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
+ L T + D S K+W + L+ D V F +L G +D +++
Sbjct: 403 NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIY 460
Query: 251 NIERGTLEREYCGHQKAITALAF 273
++ T + H T +AF
Sbjct: 461 ICKQWTEILHFTEHSGLTTGVAF 483
Score = 42.7 bits (96), Expect = 0.001
Identities = 35/177 (19%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D ++I+ G + ++D ++Q + + + P+ ++ + + +WS
Sbjct: 233 DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWS 292
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
+ P+ + + AH L+++S D + W SD R L + T
Sbjct: 293 V----PNASCVQVVRAHESAVTGLSLHATGDYLLSSSDD---QYWAFSDIQTGRVLTKVT 345
Query: 223 QRW----VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ A F D TG+ DS ++W+++ T + GH IT++AF +
Sbjct: 346 DETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSE 402
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
Query: 13 EISPTSMVAAAGFQ--HIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
+ P ++ G I+++DL V F S ++ + F +NG ++ T +D
Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTN--VANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 71 TARIWDPR 78
+ ++WD R
Sbjct: 415 SVKLWDLR 422
>BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 48.8 bits (111), Expect = 2e-05
Identities = 35/161 (21%), Positives = 69/161 (42%), Gaps = 5/161 (3%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V +V+ HP Q + I IW + Q++ E+++ +++ G + +++
Sbjct: 267 VTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYL--LSS 324
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ Y W+ S V K S +L C +F PD + T + D KIW +
Sbjct: 325 SDDQY-WAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERT 383
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
+ + + AF+ + +L T + DS +LW++ +
Sbjct: 384 NVANFPGHSGP-ITSIAFSENGYYLATAADDSSVKLWDLRK 423
Score = 44.4 bits (100), Expect = 4e-04
Identities = 50/263 (19%), Positives = 99/263 (37%), Gaps = 15/263 (5%)
Query: 15 SPTSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
S T+ + G +++ ++D SS + T + +K V+ V F + +++ D T R
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQI--LATLKGHTKKVTSVVFHPSQDLVFSASPDATIR 289
Query: 74 IWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
IW + P C ++ + ++ V + LH ++ D++T + + +
Sbjct: 290 IW---SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
Query: 133 AEA--SIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
+ S+ P G + +W L + + HS FS
Sbjct: 347 ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKER----TNVANFPGHSGPITSIAFSE 402
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
+ L T + D S K+W + L+ D V F +L G +D +++
Sbjct: 403 NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIY 460
Query: 251 NIERGTLEREYCGHQKAITALAF 273
++ T + H T +AF
Sbjct: 461 ICKQWTEILHFTEHSGLTTGVAF 483
Score = 42.7 bits (96), Expect = 0.001
Identities = 35/177 (19%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D ++I+ G + ++D ++Q + + + P+ ++ + + +WS
Sbjct: 233 DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWS 292
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
+ P+ + + AH L+++S D + W SD R L + T
Sbjct: 293 V----PNASCVQVVRAHESAVTGLSLHATGDYLLSSSDD---QYWAFSDIQTGRVLTKVT 345
Query: 223 QRW----VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ A F D TG+ DS ++W+++ T + GH IT++AF +
Sbjct: 346 DETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSE 402
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
Query: 13 EISPTSMVAAAGFQ--HIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
+ P ++ G I+++DL V F S ++ + F +NG ++ T +D
Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTN--VANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 71 TARIWDPR 78
+ ++WD R
Sbjct: 415 SVKLWDLR 422
>BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 48.8 bits (111), Expect = 2e-05
Identities = 35/161 (21%), Positives = 69/161 (42%), Gaps = 5/161 (3%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V +V+ HP Q + I IW + Q++ E+++ +++ G + +++
Sbjct: 267 VTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYL--LSS 324
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ Y W+ S V K S +L C +F PD + T + D KIW +
Sbjct: 325 SDDQY-WAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERT 383
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
+ + + AF+ + +L T + DS +LW++ +
Sbjct: 384 NVANFPGHSGP-ITSIAFSENGYYLATAADDSSVKLWDLRK 423
Score = 44.4 bits (100), Expect = 4e-04
Identities = 50/263 (19%), Positives = 99/263 (37%), Gaps = 15/263 (5%)
Query: 15 SPTSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
S T+ + G +++ ++D SS + T + +K V+ V F + +++ D T R
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQI--LATLKGHTKKVTSVVFHPSQDLVFSASPDATIR 289
Query: 74 IWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
IW + P C ++ + ++ V + LH ++ D++T + + +
Sbjct: 290 IW---SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
Query: 133 AEA--SIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
+ S+ P G + +W L + + HS FS
Sbjct: 347 ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKER----TNVANFPGHSGPITSIAFSE 402
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
+ L T + D S K+W + L+ D V F +L G +D +++
Sbjct: 403 NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIY 460
Query: 251 NIERGTLEREYCGHQKAITALAF 273
++ T + H T +AF
Sbjct: 461 ICKQWTEILHFTEHSGLTTGVAF 483
Score = 42.7 bits (96), Expect = 0.001
Identities = 35/177 (19%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D ++I+ G + ++D ++Q + + + P+ ++ + + +WS
Sbjct: 233 DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWS 292
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
+ P+ + + AH L+++S D + W SD R L + T
Sbjct: 293 V----PNASCVQVVRAHESAVTGLSLHATGDYLLSSSDD---QYWAFSDIQTGRVLTKVT 345
Query: 223 QRW----VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ A F D TG+ DS ++W+++ T + GH IT++AF +
Sbjct: 346 DETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSE 402
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
Query: 13 EISPTSMVAAAGFQ--HIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
+ P ++ G I+++DL V F S ++ + F +NG ++ T +D
Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTN--VANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 71 TARIWDPR 78
+ ++WD R
Sbjct: 415 SVKLWDLR 422
>AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein.
Length = 607
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 464 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 520
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 521 AIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 580
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 581 NAVA----WSPSGSHVVSVDKGCKAVLW 604
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 10/168 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE--QLIPEAEASIQDIAIDPAGKMMAAV 152
VNAV P + G + +W++ ++ E + + A I I D AG + A
Sbjct: 325 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 384
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+N +W++ + +T HS L KF D+ +V+ S D + K+W
Sbjct: 385 SNDFASRIWTVDDYRL----RHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 440
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
++ + + D T + + +G D R W+I ++ RE
Sbjct: 441 VCIKTVFAGSS--CNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVRE 484
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 471 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 527
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 528 APGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 587
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 588 SGSHVVSVDKGCKAVLWA 605
Score = 34.7 bits (76), Expect = 0.36
Identities = 21/97 (21%), Positives = 36/97 (37%), Gaps = 1/97 (1%)
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLDSR 236
AH +FSP S +L T D K+W + + + + F
Sbjct: 320 AHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS 379
Query: 237 FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+L S+D +R+W ++ L GH + + F
Sbjct: 380 YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKF 416
>AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3
protein.
Length = 943
Score = 48.8 bits (111), Expect = 2e-05
Identities = 39/179 (21%), Positives = 70/179 (39%), Gaps = 7/179 (3%)
Query: 74 IWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEA 133
IWD R + + ++ V + PD + VG + G I I+ L + +
Sbjct: 49 IWDLRKGEKILILQ--GLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 134 EASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDST 193
+A+I + D G +A+ + + VW + + + H + F +
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESG----LYRLKGHKDAITQALFLREKN 162
Query: 194 MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNI 252
+LVT+ D K W + + VW + + L TG+SDS R+W+I
Sbjct: 163 LLVTSGKDTMVKWWDLDTQHCFKTMVGHRTE-VWGLVLLSEEKRLITGASDSELRVWDI 220
Score = 44.8 bits (101), Expect = 3e-04
Identities = 56/263 (21%), Positives = 100/263 (38%), Gaps = 20/263 (7%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD---------PR 78
++LYDL+S N + T + + + + TGG D + + WD +
Sbjct: 478 LQLYDLASGNL--LETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQ 535
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
+ + Q+ V V P+Q + V + I+ + T + + + +
Sbjct: 536 KRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVI 595
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ I G ++A + N +W L H K + AH + +F P S + T
Sbjct: 596 CMDISHDGALIATGSADRNVKIWGLDFGDCH----KSLFAHDDSVMYLQFVPKSHLFFTA 651
Query: 199 SGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL- 257
D K W + ++ L Q +W A + ++ + S D RLW R L
Sbjct: 652 GKDHKIKQWDADKFEHIQTLEGHHQE-IWCLAVSPSGDYVVSSSHDKSLRLWERTREPLI 710
Query: 258 ---EREYCGHQKAITALAFKDQP 277
ERE + ++A +DQP
Sbjct: 711 LEEEREMEREAEYEESVAKEDQP 733
Score = 39.9 bits (89), Expect = 0.010
Identities = 30/179 (16%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Query: 102 PDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW 161
P Q+++G ++G + ++DL + + I + ++ +++ P + + W
Sbjct: 464 PGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFW 523
Query: 162 SLSGQPPHPVPKKHITAHSKYALR------C-KFSPDSTMLVTTSGDCSAKIWRTSDWAL 214
+K ++ L+ C +SP+ +L + DC+ KI+
Sbjct: 524 DFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKF 583
Query: 215 LRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L + + D + TGS+D ++W ++ G + H ++ L F
Sbjct: 584 FLSLYGHKLPVIC-MDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQF 641
Score = 33.1 bits (72), Expect = 1.1
Identities = 29/157 (18%), Positives = 58/157 (36%), Gaps = 7/157 (4%)
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKK 174
+ IWDL+ + ++ + + + P G +A G+ ++SL SG+
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEG-----NV 101
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
H K+ L + S D +W + + L L+ + A F +
Sbjct: 102 TFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDA-ITQALFLRE 160
Query: 235 SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
L T D+ + W+++ + GH+ + L
Sbjct: 161 KNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGL 197
>AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens
cDNA FLJ41882 fis, clone OCBBF2022351, weakly similar
to TIPD PROTEIN. ).
Length = 428
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 285 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 341
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 342 AIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 401
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 402 NAVA----WSPSGSHVVSVDKGCKAVLW 425
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 292 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 348
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 349 APGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 408
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 409 SGSHVVSVDKGCKAVLWA 426
Score = 35.1 bits (77), Expect = 0.27
Identities = 29/124 (23%), Positives = 51/124 (41%), Gaps = 8/124 (6%)
Query: 137 IQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLV 196
I I D AG + A +N +W++ + +T HS L KF D+ +V
Sbjct: 190 ITSIEFDSAGSYLLAASNDFASRIWTVDDYRL----RHTLTGHSGKVLSAKFLLDNARIV 245
Query: 197 TTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGT 256
+ S D + K+W ++ + + D T + + +G D R W+I +
Sbjct: 246 SGSHDRTLKLWDLRSKVCIKTVFAGSS--CNDIVCT--EQCVMSGHFDKKIRFWDIRSES 301
Query: 257 LERE 260
+ RE
Sbjct: 302 IVRE 305
>AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens
cDNA FLJ14948 fis, clone PLACE2000164, weakly similar to
TIPD PROTEIN. ).
Length = 504
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 361 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 417
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 418 AIKQTFSATGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 477
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 478 NAVA----WSPSGSHVVSVDKGCKAVLW 501
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/168 (22%), Positives = 68/168 (40%), Gaps = 10/168 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE--QLIPEAEASIQDIAIDPAGKMMAAV 152
VNA P + G + +W++ ++ E + + A I I D AG + A
Sbjct: 222 VNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 281
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+N +W++ + +T HS L KF D+ +V+ S D + K+W
Sbjct: 282 SNDFASRIWTVDDYRL----RHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 337
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
++ + + D T + + +G D R W+I ++ RE
Sbjct: 338 VCIKTVFAGSS--CNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVRE 381
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 368 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 424
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 425 ATGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 484
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 485 SGSHVVSVDKGCKAVLWA 502
Score = 35.1 bits (77), Expect = 0.27
Identities = 21/97 (21%), Positives = 36/97 (37%), Gaps = 1/97 (1%)
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLDSR 236
AH +FSP S +L T D K+W + + + + F
Sbjct: 217 AHDGEVNAAQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS 276
Query: 237 FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+L S+D +R+W ++ L GH + + F
Sbjct: 277 YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKF 313
>AK026330-1|BAB15448.1| 173|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22677 fis, clone HSI10648. ).
Length = 173
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 30 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 86
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 87 AIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 146
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 147 NAVA----WSPSGSHVVSVDKGCKAVLW 170
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 37 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 93
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 94 APGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 153
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 154 SGSHVVSVDKGCKAVLWA 171
>AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein
NMP200 protein.
Length = 504
Score = 48.8 bits (111), Expect = 2e-05
Identities = 35/161 (21%), Positives = 69/161 (42%), Gaps = 5/161 (3%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNN 154
V +V+ HP Q + I IW + Q++ E+++ +++ G + +++
Sbjct: 267 VTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYL--LSS 324
Query: 155 KGNCYVWSLSGQPPHPVPKKHITAHSKYALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA 213
+ Y W+ S V K S +L C +F PD + T + D KIW +
Sbjct: 325 SDDQY-WAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERT 383
Query: 214 LLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
+ + + AF+ + +L T + DS +LW++ +
Sbjct: 384 NVANFPGHSGP-ITSIAFSENGYYLATAADDSSVKLWDLRK 423
Score = 44.4 bits (100), Expect = 4e-04
Identities = 50/263 (19%), Positives = 99/263 (37%), Gaps = 15/263 (5%)
Query: 15 SPTSMVAAAGF-QHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR 73
S T+ + G +++ ++D SS + T + +K V+ V F + +++ D T R
Sbjct: 232 SDTNKILTGGADKNVVVFDKSSEQI--LATLKGHTKKVTSVVFHPSQDLVFSASPDATIR 289
Query: 74 IWDPRAAPRTRCQKIFQV-QAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPE 132
IW + P C ++ + ++ V + LH ++ D++T + + +
Sbjct: 290 IW---SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTD 346
Query: 133 AEA--SIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSP 190
+ S+ P G + +W L + + HS FS
Sbjct: 347 ETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKER----TNVANFPGHSGPITSIAFSE 402
Query: 191 DSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLW 250
+ L T + D S K+W + L+ D V F +L G +D +++
Sbjct: 403 NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIY 460
Query: 251 NIERGTLEREYCGHQKAITALAF 273
++ T + H T +AF
Sbjct: 461 ICKQWTEILHFTEHSGLTTGVAF 483
Score = 42.7 bits (96), Expect = 0.001
Identities = 35/177 (19%), Positives = 72/177 (40%), Gaps = 11/177 (6%)
Query: 103 DQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWS 162
D ++I+ G + ++D ++Q + + + P+ ++ + + +WS
Sbjct: 233 DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWS 292
Query: 163 LSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDT 222
+ P+ + + AH L+++S D + W SD R L + T
Sbjct: 293 V----PNASCVQVVRAHESAVTGLSLHATGDYLLSSSDD---QYWAFSDIQTGRVLTKVT 345
Query: 223 QRW----VWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKD 275
+ A F D TG+ DS ++W+++ T + GH IT++AF +
Sbjct: 346 DETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSE 402
Score = 32.7 bits (71), Expect = 1.5
Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 4/68 (5%)
Query: 13 EISPTSMVAAAGFQ--HIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDC 70
+ P ++ G I+++DL V F S ++ + F +NG ++ T +D
Sbjct: 357 QFHPDGLIFGTGTMDSQIKIWDLKERTN--VANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 71 TARIWDPR 78
+ ++WD R
Sbjct: 415 SVKLWDLR 422
>AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3
protein.
Length = 943
Score = 48.8 bits (111), Expect = 2e-05
Identities = 39/179 (21%), Positives = 70/179 (39%), Gaps = 7/179 (3%)
Query: 74 IWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEA 133
IWD R + + ++ V + PD + VG + G I I+ L + +
Sbjct: 49 IWDLRKGEKILILQ--GLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGNVTFNGH 106
Query: 134 EASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDST 193
+A+I + D G +A+ + + VW + + + H + F +
Sbjct: 107 KAAITTLKYDQLGGRLASGSKDTDIIVWDVINESG----LYRLKGHKDAITQALFLREKN 162
Query: 194 MLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNI 252
+LVT+ D K W + + VW + + L TG+SDS R+W+I
Sbjct: 163 LLVTSGKDTMVKWWDLDTQHCFKTMVGHRTE-VWGLVLLSEEKRLITGASDSELRVWDI 220
Score = 44.8 bits (101), Expect = 3e-04
Identities = 56/263 (21%), Positives = 100/263 (38%), Gaps = 20/263 (7%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWD---------PR 78
++LYDL+S N + T + + + + TGG D + + WD +
Sbjct: 478 LQLYDLASGNL--LETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQ 535
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
+ + Q+ V V P+Q + V + I+ + T + + + +
Sbjct: 536 KRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVI 595
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTT 198
+ I G ++A + N +W L H K + AH + +F P S + T
Sbjct: 596 CMDISHDGALIATGSADRNVKIWGLDFGDCH----KSLFAHDDSVMYLQFVPKSHLFFTA 651
Query: 199 SGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTL- 257
D K W + ++ L Q +W A + ++ + S D RLW R L
Sbjct: 652 GKDHKIKQWDADKFEHIQTLEGHHQE-IWCLAVSPSGDYVVSSSHDKSLRLWERTREPLI 710
Query: 258 ---EREYCGHQKAITALAFKDQP 277
ERE + ++A +DQP
Sbjct: 711 LEEEREMEREAEYEESVAKEDQP 733
Score = 39.9 bits (89), Expect = 0.010
Identities = 30/179 (16%), Positives = 69/179 (38%), Gaps = 8/179 (4%)
Query: 102 PDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVW 161
P Q+++G ++G + ++DL + + I + ++ +++ P + + W
Sbjct: 464 PGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFW 523
Query: 162 SLSGQPPHPVPKKHITAHSKYALR------C-KFSPDSTMLVTTSGDCSAKIWRTSDWAL 214
+K ++ L+ C +SP+ +L + DC+ KI+
Sbjct: 524 DFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKF 583
Query: 215 LRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L + + D + TGS+D ++W ++ G + H ++ L F
Sbjct: 584 FLSLYGHKLPVIC-MDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQF 641
Score = 33.1 bits (72), Expect = 1.1
Identities = 29/157 (18%), Positives = 58/157 (36%), Gaps = 7/157 (4%)
Query: 116 IHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKK 174
+ IWDL+ + ++ + + + P G +A G+ ++SL SG+
Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEG-----NV 101
Query: 175 HITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLD 234
H K+ L + S D +W + + L L+ + A F +
Sbjct: 102 TFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDA-ITQALFLRE 160
Query: 235 SRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITAL 271
L T D+ + W+++ + GH+ + L
Sbjct: 161 KNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGL 197
>AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein.
Length = 523
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/148 (22%), Positives = 73/148 (49%), Gaps = 12/148 (8%)
Query: 65 TGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTD 124
+G D R WD R+ R ++ + A+ L+P++++++ + ++ + DL+T+
Sbjct: 380 SGHFDKKIRFWDIRSESIVREMELL---GKITALDLNPERTELLSCSRDDLLKVIDLRTN 436
Query: 125 QNEQLIP----EAEASIQDIAIDPAGKMMAAVNNKGNCYVWS-LSGQPPHPVPKKHITAH 179
+Q + + + P G +AA + +G+ Y+WS L+G+ + K+H ++
Sbjct: 437 AIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSI 496
Query: 180 SKYALRCKFSPDSTMLVTTSGDCSAKIW 207
+ A +SP + +V+ C A +W
Sbjct: 497 NAVA----WSPSGSHVVSVDKGCKAVLW 520
Score = 45.6 bits (103), Expect = 2e-04
Identities = 38/168 (22%), Positives = 69/168 (41%), Gaps = 10/168 (5%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNE--QLIPEAEASIQDIAIDPAGKMMAAV 152
VNAV P + G + +W++ ++ E + + A I I D AG + A
Sbjct: 241 VNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAA 300
Query: 153 NNKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDW 212
+N +W++ + +T HS L KF D+ +V+ S D + K+W
Sbjct: 301 SNDFASRIWTVDDYRL----RHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSK 356
Query: 213 ALLRELRRDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIERGTLERE 260
++ + + D T + + +G D R W+I ++ RE
Sbjct: 357 VCIKTVFAGSS--CNDIVCT--EQCVMSGHFDKKIRFWDIRSESIVRE 400
Score = 38.3 bits (85), Expect = 0.029
Identities = 31/138 (22%), Positives = 63/138 (45%), Gaps = 6/138 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR--AAPRTRC 85
IR +D+ S + V E + K ++ + T + + D ++ D R A +T
Sbjct: 387 IRFWDIRSESI--VREMELLGK-ITALDLNPERTELLSCSRDDLLKVIDLRTNAIKQTFS 443
Query: 86 QKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLI-PEAEASIQDIAIDP 144
F+ + V+ PD S + G G ++IW + T + E+++ + +SI +A P
Sbjct: 444 APGFKCGSDWTRVVFSPDGSYVAAGSAEGSLYIWSVLTGKVEKVLSKQHSSSINAVAWSP 503
Query: 145 AGKMMAAVNNKGNCYVWS 162
+G + +V+ +W+
Sbjct: 504 SGSHVVSVDKGCKAVLWA 521
Score = 34.7 bits (76), Expect = 0.36
Identities = 21/97 (21%), Positives = 36/97 (37%), Gaps = 1/97 (1%)
Query: 178 AHSKYALRCKFSPDSTMLVTTSGDCSAKIWRT-SDWALLRELRRDTQRWVWDAAFTLDSR 236
AH +FSP S +L T D K+W + + + + F
Sbjct: 236 AHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS 295
Query: 237 FLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+L S+D +R+W ++ L GH + + F
Sbjct: 296 YLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKF 332
>M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.3
protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 288
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/162 (19%), Positives = 65/162 (40%), Gaps = 5/162 (3%)
Query: 112 QSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPV 171
+ I +WD +T E+ + S+QDI+ D +GK++A+ + +W G +
Sbjct: 6 EDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF--ECI 63
Query: 172 PKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAF 231
H H P+ +V+ S D + K+W ++ + WV
Sbjct: 64 RTMH--GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTF-TGHREWVRMVRP 120
Query: 232 TLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
D + + S+D R+W + + E H+ + +++
Sbjct: 121 NQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISW 162
Score = 42.3 bits (95), Expect = 0.002
Identities = 50/272 (18%), Positives = 110/272 (40%), Gaps = 23/272 (8%)
Query: 19 MVAAAGFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIWDPR 78
MV+A+ I+++D + D T + + +V + F +G + + D T ++WD +
Sbjct: 1 MVSASEDATIKVWDYETG--DFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 58
Query: 79 AAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQ 138
R V++V + P+ I+ + I +W+++T + ++
Sbjct: 59 GFECIRTMHGHDHN--VSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVR 116
Query: 139 DIAIDPAGKMMAAVNNKGNCYVWSLSGQPPHPVPKKHI--------TAHSKYALRCKFSP 190
+ + G ++A+ +N VW ++ + ++H S Y+ + +
Sbjct: 117 MVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATG 176
Query: 191 DST--------MLVTTSGDCSAKIWRTSD-WALLRELRRDTQRWVWDAAFTLDSRFLFTG 241
T L++ S D + K+W S L+ + D WV F +F+ +
Sbjct: 177 SETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXVGHDN--WVRGVLFHSGGKFILSC 234
Query: 242 SSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D R+W+ + + H+ +T+L F
Sbjct: 235 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDF 266
>CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein.
Length = 768
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 1/100 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K I H F + T S DC KIW T D LL LR + + D A
Sbjct: 174 KRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAE-ISDMAVNY 232
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
++ + GS D R+W + GH +IT++ F
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Score = 39.5 bits (88), Expect = 0.013
Identities = 50/216 (23%), Positives = 85/216 (39%), Gaps = 21/216 (9%)
Query: 54 VGFQKNGTWMYTGGEDCTARIW---DPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V F ++G ++TG +DC +IW D R R A ++ + ++ + + I G
Sbjct: 186 VAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGH-----SAEISDMAVNYENTLIAAG 240
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK----MMAAVNNKGN-CY-VWSLS 164
++ +W L+T ++ ASI I P+ K + + G C+ W +
Sbjct: 241 SCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVK 300
Query: 165 GQPPHPVPKKHITAHSK--YALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA--LLRELR 219
P K T S+ + C FS + T S D +I+ + EL
Sbjct: 301 TMKFRDRPVK-FTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELE 359
Query: 220 RDTQRWV-WDAAFTLDSRFLFTGSSDSYARLWNIER 254
T + V DS +GS D AR+W ++
Sbjct: 360 SHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ 395
Score = 33.9 bits (74), Expect = 0.63
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 193 TMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
T ++T + K+W + LL L D + +V +A D R + + D +W+
Sbjct: 436 TTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEA-HPFDQRIILSAGHDGNIFIWD 494
Query: 252 IERGTLEREY 261
++RGT R Y
Sbjct: 495 LDRGTKIRNY 504
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWM--YTGGEDCTARIW 75
IR+Y L S P+ + E + V V F NG + +G D TARIW
Sbjct: 342 IRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIW 391
>BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein.
Length = 563
Score = 48.4 bits (110), Expect = 3e-05
Identities = 25/95 (26%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 179 HSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
H Y C+ ++ T S DC+ + W L+ R T + + +++ L
Sbjct: 243 HESYVTFCQLEDEAAF--TCSADCTIRRWDVLTGQCLQVYRGHTS--IVNRILVANNQ-L 297
Query: 239 FTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
F+ S D AR+W++++G + RE+ GH+ + LA+
Sbjct: 298 FSSSYDRTARVWSVDKGQMSREFRGHRNCVLTLAY 332
Score = 38.7 bits (86), Expect = 0.022
Identities = 45/225 (20%), Positives = 87/225 (38%), Gaps = 27/225 (12%)
Query: 64 YTGGEDCTARIWDPRAAPRTRCQKIFQVQAP-VNAVMLHPDQSQIMVGDQSGIIHIWDLK 122
+T DCT R WD +C ++++ VN +++ +Q+ +W +
Sbjct: 258 FTCSADCTIRRWDVLTG---QCLQVYRGHTSIVNRILV--ANNQLFSSSYDRTARVWSVD 312
Query: 123 TDQNEQ--------LIPEAEASIQDIAIDP------AGKMMAAVNNKGNCYVWSLSGQPP 168
Q + ++ A ++ D+ P AG ++ + G VW ++
Sbjct: 313 KGQMSREFRGHRNCVLTLAYSAPWDLPSTPCAEEAAAGGLLVTGSTDGTAKVWQVASGCC 372
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H + H A L +P T T S D + + W LR R +
Sbjct: 373 HQTLRGHTGAVLCLVLD---TPGHTAF-TGSTDATIRAWDILSGEQLRVFREHRGSVI-- 426
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
L +R +++GS+D + W + G R + H++ ++AL +
Sbjct: 427 -CLELVNRLVYSGSADRTVKCWLADTGECVRTFTAHRRNVSALKY 470
Score = 34.7 bits (76), Expect = 0.36
Identities = 41/194 (21%), Positives = 77/194 (39%), Gaps = 15/194 (7%)
Query: 60 GTWMYTGGEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVGDQSGIIHIW 119
G + TG D TA++W + A Q + V ++L G I W
Sbjct: 350 GGLLVTGSTDGTAKVW--QVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAW 407
Query: 120 DLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSL-SGQPPHPVPKKHITA 178
D+ + + ++ E S+ I ++ +++ + + W +G+ + TA
Sbjct: 408 DILSGEQLRVFREHRGSV--ICLELVNRLVYSGSADRTVKCWLADTGECV-----RTFTA 460
Query: 179 HSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTLDSRFL 238
H + K+ + L T SGD A+ + L R R T ++ + + + L
Sbjct: 461 HRRNVSALKYHAGT--LFTGSGDACARAFDAQSGELRRVFRGHT--FIINC-IQVHGQVL 515
Query: 239 FTGSSDSYARLWNI 252
+T S D RLW++
Sbjct: 516 YTASHDGALRLWDV 529
Score = 33.1 bits (72), Expect = 1.1
Identities = 31/170 (18%), Positives = 63/170 (37%), Gaps = 9/170 (5%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLSGQ 166
++ G G +W + + Q + ++ + +D G + W +
Sbjct: 353 LVTGSTDGTAKVWQVASGCCHQTLRGHTGAVLCLVLDTPGHTAFTGSTDATIRAWDILSG 412
Query: 167 PPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWV 226
V ++H + ++ C + ++ + S D + K W +R +
Sbjct: 413 EQLRVFREH-----RGSVIC-LELVNRLVYSGSADRTVKCWLADTGECVRTFTAHRRNV- 465
Query: 227 WDAAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAFKDQ 276
+A + LFTGS D+ AR ++ + G L R + GH I + Q
Sbjct: 466 --SALKYHAGTLFTGSGDACARAFDAQSGELRRVFRGHTFIINCIQVHGQ 513
>BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC022050-1|AAH22050.1| 551|Homo sapiens DMXL2 protein protein.
Length = 551
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/146 (23%), Positives = 67/146 (45%), Gaps = 4/146 (2%)
Query: 24 GFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR---IWDPRAA 80
GF I + +++NP P +++ SK S F + + + T G R +WD +
Sbjct: 343 GFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLIS 402
Query: 81 PRTRCQKIFQVQAPVNAVMLHPDQSQIMV-GDQSGIIHIWDLKTDQNEQLIPEAEASIQD 139
P F V+ + + Q+++ G + G + I+D++ Q +++I+
Sbjct: 403 PGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKA 462
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSG 165
+A+DP + + +GN VW L+G
Sbjct: 463 LALDPYEEYFTTGSAEGNIKVWRLTG 488
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/107 (22%), Positives = 41/107 (38%), Gaps = 2/107 (1%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEA-EASIQDIAIDPAGKMMAAVN 153
V + HP + G Q G + +++ Q +A A + + + G +
Sbjct: 281 VKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVAD 340
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSG 200
+G +W ++ +P P HSK F S+ LV TSG
Sbjct: 341 GEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSS-LVATSG 386
>BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 66 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 123
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 124 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 182
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 238
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 239 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 295
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 296 QTLFAGYTDNLVRVWQVTIGT 316
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 70
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 71 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 113
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 31 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 90
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 91 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 146
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 147 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 191
>AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repeat
domain containing 3 variant BRWD3-B protein.
Length = 1631
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 1/100 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K I H F + T S DC KIW T D LL LR + + D A
Sbjct: 3 KRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAE-ISDMAVNY 61
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
++ + GS D R+W + GH +IT++ F
Sbjct: 62 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 101
Score = 39.5 bits (88), Expect = 0.013
Identities = 50/216 (23%), Positives = 85/216 (39%), Gaps = 21/216 (9%)
Query: 54 VGFQKNGTWMYTGGEDCTARIW---DPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V F ++G ++TG +DC +IW D R R A ++ + ++ + + I G
Sbjct: 15 VAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGH-----SAEISDMAVNYENTLIAAG 69
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK----MMAAVNNKGN-CY-VWSLS 164
++ +W L+T ++ ASI I P+ K + + G C+ W +
Sbjct: 70 SCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVK 129
Query: 165 GQPPHPVPKKHITAHSK--YALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA--LLRELR 219
P K T S+ + C FS + T S D +I+ + EL
Sbjct: 130 TMKFRDRPVK-FTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELE 188
Query: 220 RDTQRWV-WDAAFTLDSRFLFTGSSDSYARLWNIER 254
T + V DS +GS D AR+W ++
Sbjct: 189 SHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ 224
Score = 33.9 bits (74), Expect = 0.63
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 193 TMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
T ++T + K+W + LL L D + +V +A D R + + D +W+
Sbjct: 265 TTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEA-HPFDQRIILSAGHDGNIFIWD 323
Query: 252 IERGTLEREY 261
++RGT R Y
Sbjct: 324 LDRGTKIRNY 333
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWM--YTGGEDCTARIW 75
IR+Y L S P+ + E + V V F NG + +G D TARIW
Sbjct: 171 IRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIW 220
>AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 variant BRWD3-A protein.
Length = 1802
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 1/100 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K I H F + T S DC KIW T D LL LR + + D A
Sbjct: 174 KRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAE-ISDMAVNY 232
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
++ + GS D R+W + GH +IT++ F
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Score = 39.5 bits (88), Expect = 0.013
Identities = 50/216 (23%), Positives = 85/216 (39%), Gaps = 21/216 (9%)
Query: 54 VGFQKNGTWMYTGGEDCTARIW---DPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V F ++G ++TG +DC +IW D R R A ++ + ++ + + I G
Sbjct: 186 VAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGH-----SAEISDMAVNYENTLIAAG 240
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK----MMAAVNNKGN-CY-VWSLS 164
++ +W L+T ++ ASI I P+ K + + G C+ W +
Sbjct: 241 SCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVK 300
Query: 165 GQPPHPVPKKHITAHSK--YALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA--LLRELR 219
P K T S+ + C FS + T S D +I+ + EL
Sbjct: 301 TMKFRDRPVK-FTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELE 359
Query: 220 RDTQRWV-WDAAFTLDSRFLFTGSSDSYARLWNIER 254
T + V DS +GS D AR+W ++
Sbjct: 360 SHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ 395
Score = 33.9 bits (74), Expect = 0.63
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 193 TMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
T ++T + K+W + LL L D + +V +A D R + + D +W+
Sbjct: 436 TTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEA-HPFDQRIILSAGHDGNIFIWD 494
Query: 252 IERGTLEREY 261
++RGT R Y
Sbjct: 495 LDRGTKIRNY 504
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWM--YTGGEDCTARIW 75
IR+Y L S P+ + E + V V F NG + +G D TARIW
Sbjct: 342 IRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIW 391
>AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7
protein.
Length = 347
Score = 48.4 bits (110), Expect = 3e-05
Identities = 59/261 (22%), Positives = 109/261 (41%), Gaps = 23/261 (8%)
Query: 9 VNSLEISPTSMVAAAGFQH--IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTG 66
V+ + IS A +G +RL+DL++ F +K+V V F + + +G
Sbjct: 96 VSDVVISSDGQFALSGSWDGTLRLWDLTTGTT--TRRFVGHTKDVLSVAFSSDNRQIVSG 153
Query: 67 GEDCTARIWDPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQ--IMVGDQSGIIHIWDLKTD 124
D T ++W+ + Q + V+ V P+ S I+ ++ +W+L
Sbjct: 154 SRDKTIKLWNTLGVCKYTVQDESHSEW-VSCVRFSPNSSNPIIVSCGWDKLVKVWNLANC 212
Query: 125 QNEQLIPEAEASIQDIAIDPAGKMMAAVNNKGNCYVWSLS-GQPPHPVPKKHITAHSKYA 183
+ + + + + P G + A+ G +W L+ G+ + + I A
Sbjct: 213 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIIN----A 268
Query: 184 LRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDA--------AFTLDS 235
L C FSP+ L +G S KIW ++ EL+++ A A++ D
Sbjct: 269 L-C-FSPNRYWLCAATGP-SIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADG 325
Query: 236 RFLFTGSSDSYARLWNIERGT 256
+ LF G +D+ R+W + GT
Sbjct: 326 QTLFAGYTDNLVRVWQVTIGT 346
Score = 47.6 bits (108), Expect = 5e-05
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 5/103 (4%)
Query: 176 ITAHSKYALRCKFSPD-STMLVTTSGDCSAKIWRTS----DWALLRELRRDTQRWVWDAA 230
+ H+ + + +P M+++ S D + +W+ + ++ + + R +V D
Sbjct: 41 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVV 100
Query: 231 FTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
+ D +F +GS D RLW++ GT R + GH K + ++AF
Sbjct: 101 ISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAF 143
Score = 45.2 bits (102), Expect = 3e-04
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 11/165 (6%)
Query: 107 IMVGDQSGIIHIWDLKTDQNEQLIPEAEAS-----IQDIAIDPAGKMMAAVNNKGNCYVW 161
I+ + I +W L D+ IP+ + D+ I G+ + + G +W
Sbjct: 61 ILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLW 120
Query: 162 SLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRD 221
L+ + H+K L FS D+ +V+ S D + K+W T
Sbjct: 121 DLTTG----TTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDES 176
Query: 222 TQRWVWDAAFTLDSR--FLFTGSSDSYARLWNIERGTLEREYCGH 264
WV F+ +S + + D ++WN+ L+ + GH
Sbjct: 177 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGH 221
>AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 1/100 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K I H F + T S DC KIW T D LL LR + + D A
Sbjct: 174 KRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAE-ISDMAVNY 232
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
++ + GS D R+W + GH +IT++ F
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Score = 39.5 bits (88), Expect = 0.013
Identities = 50/216 (23%), Positives = 85/216 (39%), Gaps = 21/216 (9%)
Query: 54 VGFQKNGTWMYTGGEDCTARIW---DPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V F ++G ++TG +DC +IW D R R A ++ + ++ + + I G
Sbjct: 186 VAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGH-----SAEISDMAVNYENTLIAAG 240
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK----MMAAVNNKGN-CY-VWSLS 164
++ +W L+T ++ ASI I P+ K + + G C+ W +
Sbjct: 241 SCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVK 300
Query: 165 GQPPHPVPKKHITAHSK--YALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA--LLRELR 219
P K T S+ + C FS + T S D +I+ + EL
Sbjct: 301 TMKFRDRPVK-FTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELE 359
Query: 220 RDTQRWV-WDAAFTLDSRFLFTGSSDSYARLWNIER 254
T + V DS +GS D AR+W ++
Sbjct: 360 SHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ 395
Score = 33.9 bits (74), Expect = 0.63
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 193 TMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
T ++T + K+W + LL L D + +V +A D R + + D +W+
Sbjct: 436 TTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEA-HPFDQRIILSAGHDGNIFIWD 494
Query: 252 IERGTLEREY 261
++RGT R Y
Sbjct: 495 LDRGTKIRNY 504
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWM--YTGGEDCTARIW 75
IR+Y L S P+ + E + V V F NG + +G D TARIW
Sbjct: 342 IRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIW 391
>AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 1/100 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K I H F + T S DC KIW T D LL LR + + D A
Sbjct: 174 KRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAE-ISDMAVNY 232
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
++ + GS D R+W + GH +IT++ F
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Score = 39.5 bits (88), Expect = 0.013
Identities = 50/216 (23%), Positives = 85/216 (39%), Gaps = 21/216 (9%)
Query: 54 VGFQKNGTWMYTGGEDCTARIW---DPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V F ++G ++TG +DC +IW D R R A ++ + ++ + + I G
Sbjct: 186 VAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGH-----SAEISDMAVNYENTLIAAG 240
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK----MMAAVNNKGN-CY-VWSLS 164
++ +W L+T ++ ASI I P+ K + + G C+ W +
Sbjct: 241 SCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVK 300
Query: 165 GQPPHPVPKKHITAHSK--YALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA--LLRELR 219
P K T S+ + C FS + T S D +I+ + EL
Sbjct: 301 TMKFRDRPVK-FTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELE 359
Query: 220 RDTQRWV-WDAAFTLDSRFLFTGSSDSYARLWNIER 254
T + V DS +GS D AR+W ++
Sbjct: 360 SHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ 395
Score = 33.9 bits (74), Expect = 0.63
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 193 TMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
T ++T + K+W + LL L D + +V +A D R + + D +W+
Sbjct: 436 TTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEA-HPFDQRIILSAGHDGNIFIWD 494
Query: 252 IERGTLEREY 261
++RGT R Y
Sbjct: 495 LDRGTKIRNY 504
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWM--YTGGEDCTARIW 75
IR+Y L S P+ + E + V V F NG + +G D TARIW
Sbjct: 342 IRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIW 391
>AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 48.4 bits (110), Expect = 3e-05
Identities = 29/100 (29%), Positives = 40/100 (40%), Gaps = 1/100 (1%)
Query: 174 KHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWDAAFTL 233
K I H F + T S DC KIW T D LL LR + + D A
Sbjct: 174 KRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAE-ISDMAVNY 232
Query: 234 DSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
++ + GS D R+W + GH +IT++ F
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF 272
Score = 39.5 bits (88), Expect = 0.013
Identities = 50/216 (23%), Positives = 85/216 (39%), Gaps = 21/216 (9%)
Query: 54 VGFQKNGTWMYTGGEDCTARIW---DPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V F ++G ++TG +DC +IW D R R A ++ + ++ + + I G
Sbjct: 186 VAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGH-----SAEISDMAVNYENTLIAAG 240
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDPAGK----MMAAVNNKGN-CY-VWSLS 164
++ +W L+T ++ ASI I P+ K + + G C+ W +
Sbjct: 241 SCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVK 300
Query: 165 GQPPHPVPKKHITAHSK--YALRC-KFSPDSTMLVTTSGDCSAKIWRTSDWA--LLRELR 219
P K T S+ + C FS + T S D +I+ + EL
Sbjct: 301 TMKFRDRPVK-FTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELE 359
Query: 220 RDTQRWV-WDAAFTLDSRFLFTGSSDSYARLWNIER 254
T + V DS +GS D AR+W ++
Sbjct: 360 SHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQ 395
Score = 33.9 bits (74), Expect = 0.63
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 193 TMLVTTSGDCSAKIWRTSDWALLRELR-RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWN 251
T ++T + K+W + LL L D + +V +A D R + + D +W+
Sbjct: 436 TTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEA-HPFDQRIILSAGHDGNIFIWD 494
Query: 252 IERGTLEREY 261
++RGT R Y
Sbjct: 495 LDRGTKIRNY 504
Score = 33.1 bits (72), Expect = 1.1
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWM--YTGGEDCTARIW 75
IR+Y L S P+ + E + V V F NG + +G D TARIW
Sbjct: 342 IRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIW 391
>AF389880-1|AAL93215.1| 3036|Homo sapiens rabconnectin protein.
Length = 3036
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/146 (23%), Positives = 67/146 (45%), Gaps = 4/146 (2%)
Query: 24 GFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR---IWDPRAA 80
GF I + +++NP P +++ SK S F + + + T G R +WD +
Sbjct: 2828 GFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLIS 2887
Query: 81 PRTRCQKIFQVQAPVNAVMLHPDQSQIMV-GDQSGIIHIWDLKTDQNEQLIPEAEASIQD 139
P F V+ + + Q+++ G + G + I+D++ Q +++I+
Sbjct: 2888 PGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKA 2947
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSG 165
+A+DP + + +GN VW L+G
Sbjct: 2948 LALDPYEEYFTTGSAEGNIKVWRLTG 2973
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/107 (22%), Positives = 41/107 (38%), Gaps = 2/107 (1%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEA-EASIQDIAIDPAGKMMAAVN 153
V + HP + G Q G + +++ Q +A A + + + G +
Sbjct: 2766 VKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVAD 2825
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSG 200
+G +W ++ +P P HSK F S+ LV TSG
Sbjct: 2826 GEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSS-LVATSG 2871
>AB020663-1|BAA74879.2| 2237|Homo sapiens KIAA0856 protein protein.
Length = 2237
Score = 48.4 bits (110), Expect = 3e-05
Identities = 34/146 (23%), Positives = 67/146 (45%), Gaps = 4/146 (2%)
Query: 24 GFQHIRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTAR---IWDPRAA 80
GF I + +++NP P +++ SK S F + + + T G R +WD +
Sbjct: 2029 GFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLIS 2088
Query: 81 PRTRCQKIFQVQAPVNAVMLHPDQSQIMV-GDQSGIIHIWDLKTDQNEQLIPEAEASIQD 139
P F V+ + + Q+++ G + G + I+D++ Q +++I+
Sbjct: 2089 PGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKA 2148
Query: 140 IAIDPAGKMMAAVNNKGNCYVWSLSG 165
+A+DP + + +GN VW L+G
Sbjct: 2149 LALDPYEEYFTTGSAEGNIKVWRLTG 2174
Score = 33.1 bits (72), Expect = 1.1
Identities = 24/107 (22%), Positives = 41/107 (38%), Gaps = 2/107 (1%)
Query: 95 VNAVMLHPDQSQIMVGDQSGIIHIWDLKTDQNEQLIPEA-EASIQDIAIDPAGKMMAAVN 153
V + HP + G Q G + +++ Q +A A + + + G +
Sbjct: 1967 VKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVAD 2026
Query: 154 NKGNCYVWSLSGQPPHPVPKKHITAHSKYALRCKFSPDSTMLVTTSG 200
+G +W ++ +P P HSK F S+ LV TSG
Sbjct: 2027 GEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSS-LVATSG 2072
>BC021905-1|AAH21905.1| 896|Homo sapiens Unknown (protein for
IMAGE:4341693) protein.
Length = 896
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/105 (29%), Positives = 40/105 (38%), Gaps = 1/105 (0%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H K I H F + T S DC KIW T D LL LR + D
Sbjct: 172 HMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAE-ISD 230
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
A ++ + GS D R+W + GH +IT+L F
Sbjct: 231 MAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQF 275
Score = 44.4 bits (100), Expect = 4e-04
Identities = 50/215 (23%), Positives = 89/215 (41%), Gaps = 21/215 (9%)
Query: 54 VGFQKNGTWMYTGGEDCTARIW---DPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V F + G ++TG +DC +IW D R R A ++ + ++ + + I G
Sbjct: 189 VTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGH-----AAEISDMAVNYENTMIAAG 243
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDP----AGKMMAAVNNKGN-CY-VWSLS 164
+I +W L+T ++ ASI + P + + +++ G C+ +W
Sbjct: 244 SCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAG 303
Query: 165 GQPPHPVPKKHITAHSKYALR--C-KFSPDSTMLVTTSGDCSAKIW--RTSDWALLRELR 219
+P P K T + ++ C FS L T S D +++ + + EL
Sbjct: 304 TLKINPRPAK-FTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELE 362
Query: 220 RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
T + V F+ S +GS D AR+W +R
Sbjct: 363 FHTDK-VDSIQFSNTSNRFVSGSRDGTARIWQFKR 396
Score = 33.5 bits (73), Expect = 0.83
Identities = 15/48 (31%), Positives = 22/48 (45%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIW 75
IR+Y S P+ ++ E + V + F +G D TARIW
Sbjct: 345 IRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIW 392
>AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( Human DNA
sequence from clone RP11-173D14 on chromosome 6. ).
Length = 1821
Score = 48.0 bits (109), Expect = 4e-05
Identities = 31/105 (29%), Positives = 40/105 (38%), Gaps = 1/105 (0%)
Query: 169 HPVPKKHITAHSKYALRCKFSPDSTMLVTTSGDCSAKIWRTSDWALLRELRRDTQRWVWD 228
H K I H F + T S DC KIW T D LL LR + D
Sbjct: 172 HMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAE-ISD 230
Query: 229 AAFTLDSRFLFTGSSDSYARLWNIERGTLEREYCGHQKAITALAF 273
A ++ + GS D R+W + GH +IT+L F
Sbjct: 231 MAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQF 275
Score = 44.4 bits (100), Expect = 4e-04
Identities = 50/215 (23%), Positives = 89/215 (41%), Gaps = 21/215 (9%)
Query: 54 VGFQKNGTWMYTGGEDCTARIW---DPRAAPRTRCQKIFQVQAPVNAVMLHPDQSQIMVG 110
V F + G ++TG +DC +IW D R R A ++ + ++ + + I G
Sbjct: 189 VTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGH-----AAEISDMAVNYENTMIAAG 243
Query: 111 DQSGIIHIWDLKTDQNEQLIPEAEASIQDIAIDP----AGKMMAAVNNKGN-CY-VWSLS 164
+I +W L+T ++ ASI + P + + +++ G C+ +W
Sbjct: 244 SCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAG 303
Query: 165 GQPPHPVPKKHITAHSKYALR--C-KFSPDSTMLVTTSGDCSAKIW--RTSDWALLRELR 219
+P P K T + ++ C FS L T S D +++ + + EL
Sbjct: 304 TLKINPRPAK-FTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELE 362
Query: 220 RDTQRWVWDAAFTLDSRFLFTGSSDSYARLWNIER 254
T + V F+ S +GS D AR+W +R
Sbjct: 363 FHTDK-VDSIQFSNTSNRFVSGSRDGTARIWQFKR 396
Score = 33.5 bits (73), Expect = 0.83
Identities = 15/48 (31%), Positives = 22/48 (45%)
Query: 28 IRLYDLSSANPDPVTTFEDISKNVSRVGFQKNGTWMYTGGEDCTARIW 75
IR+Y S P+ ++ E + V + F +G D TARIW
Sbjct: 345 IRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIW 392
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.132 0.420
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 45,241,008
Number of Sequences: 224733
Number of extensions: 1906874
Number of successful extensions: 9377
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 493
Number of HSP's successfully gapped in prelim test: 313
Number of HSP's that attempted gapping in prelim test: 4120
Number of HSP's gapped (non-prelim): 3354
length of query: 278
length of database: 73,234,838
effective HSP length: 89
effective length of query: 189
effective length of database: 53,233,601
effective search space: 10061150589
effective search space used: 10061150589
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 65 (30.3 bits)
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