Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005287-TA|BGIBMGA005287-PA|IPR008977|PHM/PNGase F Fold,
IPR008994|Nucleic acid-binding, OB-fold, IPR011129|Cold shock protein,
IPR000323|Copper type II, ascorbate-dependent monooxygenase, core,
IPR002059|Cold-shock protein, DNA-binding,
IPR000945|Dopamine-beta-monooxygenase
(351 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X13256-1|CAA31632.1| 603|Homo sapiens dopamine beta-hydroxylase... 190 6e-48
X13255-1|CAA31631.1| 603|Homo sapiens dopamine beta-hydroxylase... 190 6e-48
BC017174-1|AAH17174.1| 603|Homo sapiens DBH protein protein. 190 6e-48
AL365494-1|CAI13354.2| 617|Homo sapiens dopamine beta-hydroxyla... 190 6e-48
Y00096-1|CAA68285.1| 603|Homo sapiens protein ( Human mRNA for ... 189 1e-47
AK074879-1|BAC11263.1| 544|Homo sapiens protein ( Homo sapiens ... 143 9e-34
BC018756-1|AAH18756.1| 613|Homo sapiens monooxygenase, DBH-like... 142 1e-33
AY359094-1|AAQ89452.1| 613|Homo sapiens dopamine-oxygenase prot... 142 1e-33
AY007239-1|AAG09636.1| 545|Homo sapiens monooxygenase X protein. 142 1e-33
AL357034-4|CAI15718.1| 613|Homo sapiens monooxygenase, DBH-like... 142 1e-33
AL357034-1|CAI15715.1| 545|Homo sapiens monooxygenase, DBH-like... 142 1e-33
AL023578-2|CAI19938.1| 613|Homo sapiens monooxygenase, DBH-like... 142 1e-33
AL023578-1|CAI19937.1| 545|Homo sapiens monooxygenase, DBH-like... 142 1e-33
BC108283-1|AAI08284.1| 147|Homo sapiens calcium regulated heat ... 117 7e-26
BC003366-1|AAH03366.1| 147|Homo sapiens calcium regulated heat ... 117 7e-26
AF115345-1|AAD25021.1| 147|Homo sapiens calcium-regulated heat ... 116 2e-25
CR456457-1|CAG30343.1| 153|Homo sapiens dJ347H13.2 protein. 111 5e-24
BC067113-1|AAH67113.1| 153|Homo sapiens CSDC2 protein protein. 111 5e-24
AL023553-5|CAB46024.1| 153|Homo sapiens protein ( Human DNA seq... 111 5e-24
AB027011-1|BAA84704.1| 153|Homo sapiens RNA-binding protein PIP... 111 5e-24
AL365494-2|CAI13353.1| 244|Homo sapiens dopamine beta-hydroxyla... 90 9e-18
AL080058-1|CAB45692.1| 335|Homo sapiens hypothetical protein pr... 73 2e-12
S75038-1|AAB32776.1| 905|Homo sapiens pancreatic peptidylglycin... 63 2e-09
S75037-1|AAB32775.1| 971|Homo sapiens pancreatic peptidylglycin... 63 2e-09
M37721-1|AAA36414.1| 974|Homo sapiens peptidylglycine alpha-ami... 63 2e-09
BT007419-1|AAP36087.1| 866|Homo sapiens peptidylglycine alpha-a... 63 2e-09
BC018127-1|AAH18127.1| 866|Homo sapiens peptidylglycine alpha-a... 63 2e-09
AB095007-1|BAC22594.1| 973|Homo sapiens peptidylglycine alpha-a... 63 2e-09
AF010472-1|AAD01439.1| 825|Homo sapiens alpha-amidating monooxy... 62 3e-09
>X13256-1|CAA31632.1| 603|Homo sapiens dopamine beta-hydroxylase
preprotein (AA -25 to 578) protein.
Length = 603
Score = 190 bits (463), Expect = 6e-48
Identities = 102/241 (42%), Positives = 145/241 (60%), Gaps = 11/241 (4%)
Query: 15 QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTP----PGLQKANGYQLRIT 70
+DGTVH+V+ +++ F S + G RV+LL P P L ++ + +
Sbjct: 148 EDGTVHLVYGI-LEEPFRSLEAINGSGLQM--GLQRVQLLKPNIPEPELP-SDACTMEVQ 203
Query: 71 NKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDPHK 130
++++P +TTYWC + LP+ + HHI+++E +T GNE LVHHMEVF C +
Sbjct: 204 APNIQIPSQETTYWCYIKELPKGFSR--HHIIKYEPIVTKGNEALVHHMEVFQCAPEMDS 261
Query: 131 EMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEVHY 190
+P + G C + +P C V AAWA+GA F YP+EAGL GGP +++Y+ LEVHY
Sbjct: 262 -VPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHY 320
Query: 191 NNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAFPLTGYCIPQC 250
+NP + + DSSGI LY T + R ++A IMELGL YT MAIP + AF LTGYC +C
Sbjct: 321 HNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKC 380
Query: 251 T 251
T
Sbjct: 381 T 381
>X13255-1|CAA31631.1| 603|Homo sapiens dopamine beta-hydroxylase
preprotein (AA -25 to 578) protein.
Length = 603
Score = 190 bits (463), Expect = 6e-48
Identities = 102/241 (42%), Positives = 145/241 (60%), Gaps = 11/241 (4%)
Query: 15 QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTP----PGLQKANGYQLRIT 70
+DGTVH+V+ +++ F S + G RV+LL P P L ++ + +
Sbjct: 148 EDGTVHLVYGI-LEEPFRSLEAINGSGLQM--GLQRVQLLKPNIPEPELP-SDACTMEVQ 203
Query: 71 NKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDPHK 130
++++P +TTYWC + LP+ + HHI+++E +T GNE LVHHMEVF C +
Sbjct: 204 APNIQIPSQETTYWCYIKELPKGFSR--HHIIKYEPIVTKGNEALVHHMEVFQCAPEMDS 261
Query: 131 EMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEVHY 190
+P + G C + +P C V AAWA+GA F YP+EAGL GGP +++Y+ LEVHY
Sbjct: 262 -VPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHY 320
Query: 191 NNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAFPLTGYCIPQC 250
+NP + + DSSGI LY T + R ++A IMELGL YT MAIP + AF LTGYC +C
Sbjct: 321 HNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKC 380
Query: 251 T 251
T
Sbjct: 381 T 381
>BC017174-1|AAH17174.1| 603|Homo sapiens DBH protein protein.
Length = 603
Score = 190 bits (463), Expect = 6e-48
Identities = 102/241 (42%), Positives = 145/241 (60%), Gaps = 11/241 (4%)
Query: 15 QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTP----PGLQKANGYQLRIT 70
+DGTVH+V+ +++ F S + G RV+LL P P L ++ + +
Sbjct: 148 EDGTVHLVYGI-LEEPFRSLEAINGSGLQM--GLQRVQLLKPNIPEPELP-SDACTMEVQ 203
Query: 71 NKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDPHK 130
++++P +TTYWC + LP+ + HHI+++E +T GNE LVHHMEVF C +
Sbjct: 204 APNIQIPSQETTYWCYIKELPKGFSR--HHIIKYEPIVTKGNEALVHHMEVFQCAPEMDS 261
Query: 131 EMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEVHY 190
+P + G C + +P C V AAWA+GA F YP+EAGL GGP +++Y+ LEVHY
Sbjct: 262 -VPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHY 320
Query: 191 NNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAFPLTGYCIPQC 250
+NP + + DSSGI LY T + R ++A IMELGL YT MAIP + AF LTGYC +C
Sbjct: 321 HNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKC 380
Query: 251 T 251
T
Sbjct: 381 T 381
>AL365494-1|CAI13354.2| 617|Homo sapiens dopamine beta-hydroxylase
(dopamine beta-monooxygenase) protein.
Length = 617
Score = 190 bits (463), Expect = 6e-48
Identities = 102/241 (42%), Positives = 145/241 (60%), Gaps = 11/241 (4%)
Query: 15 QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTP----PGLQKANGYQLRIT 70
+DGTVH+V+ +++ F S + G RV+LL P P L ++ + +
Sbjct: 162 EDGTVHLVYGI-LEEPFRSLEAINGSGLQM--GLQRVQLLKPNIPEPELP-SDACTMEVQ 217
Query: 71 NKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDPHK 130
++++P +TTYWC + LP+ + HHI+++E +T GNE LVHHMEVF C +
Sbjct: 218 APNIQIPSQETTYWCYIKELPKGFSR--HHIIKYEPIVTKGNEALVHHMEVFQCAPEMDS 275
Query: 131 EMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEVHY 190
+P + G C + +P C V AAWA+GA F YP+EAGL GGP +++Y+ LEVHY
Sbjct: 276 -VPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHY 334
Query: 191 NNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAFPLTGYCIPQC 250
+NP + + DSSGI LY T + R ++A IMELGL YT MAIP + AF LTGYC +C
Sbjct: 335 HNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKC 394
Query: 251 T 251
T
Sbjct: 395 T 395
>Y00096-1|CAA68285.1| 603|Homo sapiens protein ( Human mRNA for
dopamine beta-hydroxylase (EC 1.14.17.1). ).
Length = 603
Score = 189 bits (461), Expect = 1e-47
Identities = 102/241 (42%), Positives = 145/241 (60%), Gaps = 11/241 (4%)
Query: 15 QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTP----PGLQKANGYQLRIT 70
+DGTVH+V+ +++ F S + G RV+LL P P L ++ + +
Sbjct: 148 EDGTVHLVYGI-LEEPFRSLEAINGSGLQM--GLQRVQLLKPNIPEPELP-SDTCTMEVQ 203
Query: 71 NKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDPHK 130
++++P +TTYWC + LP+ + HHI+++E +T GNE LVHHMEVF C +
Sbjct: 204 APNIQIPSQETTYWCYIKELPKGFSR--HHIIKYEPIVTKGNEALVHHMEVFQCAPEMDS 261
Query: 131 EMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEVHY 190
+P + G C + +P C V AAWA+GA F YP+EAGL GGP +++Y+ LEVHY
Sbjct: 262 -VPHFSGPCDSKMKPDRLNYCRHVLAAWALGAKAFYYPEEAGLAFGGPGSSRYLRLEVHY 320
Query: 191 NNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAFPLTGYCIPQC 250
+NP + + DSSGI LY T + R ++A IMELGL YT MAIP + AF LTGYC +C
Sbjct: 321 HNPLVIEGRNDSSGIRLYYTAKLRRFNAGIMELGLVYTPVMAIPPRETAFILTGYCTDKC 380
Query: 251 T 251
T
Sbjct: 381 T 381
>AK074879-1|BAC11263.1| 544|Homo sapiens protein ( Homo sapiens
cDNA FLJ90398 fis, clone NT2RP2005883, weakly similar to
DOPAMINE-BETA-MONOOXYGENASE PRECURSOR (EC 1.14.17.1). ).
Length = 544
Score = 143 bits (346), Expect = 9e-34
Identities = 84/250 (33%), Positives = 122/250 (48%), Gaps = 11/250 (4%)
Query: 5 LRPARINGTS-QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTPPG---LQ 60
L IN S D TV V+WA+ G G +RLL P L
Sbjct: 57 LHTCDINDKSITDSTVRVIWAY----YHEDAGEAGPKYHDSNRGTKSLRLLNPEKTSVLS 112
Query: 61 KANGYQLRITNKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHME 120
A Y + N+D+ +P DTTYWC++ ++P F + HH+++ E I G+E LVHH+
Sbjct: 113 TALPY-FDLVNQDVPIPNKDTTYWCQMFKIPVF--QEKHHVIKVEPVIQRGHESLVHHIL 169
Query: 121 VFYCDEDPHKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKA 180
++ C + + + C+ P +C V AWA+G F+YP GL LG P
Sbjct: 170 LYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLD 229
Query: 181 NKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAF 240
YV+LEVHY+NP + +D+SG+ L+ T R YDA ++E GL + IP F
Sbjct: 230 PHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEF 289
Query: 241 PLTGYCIPQC 250
G+C +C
Sbjct: 290 QSEGHCTLEC 299
>BC018756-1|AAH18756.1| 613|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 613
Score = 142 bits (345), Expect = 1e-33
Identities = 84/250 (33%), Positives = 123/250 (49%), Gaps = 11/250 (4%)
Query: 5 LRPARINGTS-QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTPPG---LQ 60
L IN S D TV V+WA+ + G G +RLL P L
Sbjct: 126 LHTCDINDKSITDSTVRVIWAYHHE----DAGEAGPKYHDSNRGTKSLRLLNPEKTSVLS 181
Query: 61 KANGYQLRITNKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHME 120
A Y + N+D+ +P DTTYWC++ ++P F + HH+++ E I G+E LVHH+
Sbjct: 182 TALPY-FDLVNQDVPIPNKDTTYWCQMFKIPVF--QEKHHVIKVEPVIQRGHESLVHHIL 238
Query: 121 VFYCDEDPHKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKA 180
++ C + + + C+ P +C V AWA+G F+YP GL LG P
Sbjct: 239 LYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLD 298
Query: 181 NKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAF 240
YV+LEVHY+NP + +D+SG+ L+ T R YDA ++E GL + IP F
Sbjct: 299 PHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEF 358
Query: 241 PLTGYCIPQC 250
G+C +C
Sbjct: 359 QSEGHCTLEC 368
>AY359094-1|AAQ89452.1| 613|Homo sapiens dopamine-oxygenase
protein.
Length = 613
Score = 142 bits (345), Expect = 1e-33
Identities = 84/250 (33%), Positives = 123/250 (49%), Gaps = 11/250 (4%)
Query: 5 LRPARINGTS-QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTPPG---LQ 60
L IN S D TV V+WA+ + G G +RLL P L
Sbjct: 126 LHTCDINDKSITDSTVRVIWAYHHE----DAGEAGPKYHDSNRGTKSLRLLNPEKTSVLS 181
Query: 61 KANGYQLRITNKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHME 120
A Y + N+D+ +P DTTYWC++ ++P F + HH+++ E I G+E LVHH+
Sbjct: 182 TALPY-FDLVNQDVPIPNKDTTYWCQMFKIPVF--QEKHHVIKVEPVIQRGHESLVHHIL 238
Query: 121 VFYCDEDPHKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKA 180
++ C + + + C+ P +C V AWA+G F+YP GL LG P
Sbjct: 239 LYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLD 298
Query: 181 NKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAF 240
YV+LEVHY+NP + +D+SG+ L+ T R YDA ++E GL + IP F
Sbjct: 299 PHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEF 358
Query: 241 PLTGYCIPQC 250
G+C +C
Sbjct: 359 QSEGHCTLEC 368
>AY007239-1|AAG09636.1| 545|Homo sapiens monooxygenase X protein.
Length = 545
Score = 142 bits (345), Expect = 1e-33
Identities = 84/250 (33%), Positives = 123/250 (49%), Gaps = 11/250 (4%)
Query: 5 LRPARINGTS-QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTPPG---LQ 60
L IN S D TV V+WA+ + G G +RLL P L
Sbjct: 58 LHTCDINDKSITDSTVRVIWAYHHE----DAGEAGPKYHDSNRGTKSLRLLNPEKTSVLS 113
Query: 61 KANGYQLRITNKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHME 120
A Y + N+D+ +P DTTYWC++ ++P F + HH+++ E I G+E LVHH+
Sbjct: 114 TALPY-FDLVNQDVPIPNKDTTYWCQMFKIPVF--QEKHHVIKVEPVIQRGHESLVHHIL 170
Query: 121 VFYCDEDPHKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKA 180
++ C + + + C+ P +C V AWA+G F+YP GL LG P
Sbjct: 171 LYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLD 230
Query: 181 NKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAF 240
YV+LEVHY+NP + +D+SG+ L+ T R YDA ++E GL + IP F
Sbjct: 231 PHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEF 290
Query: 241 PLTGYCIPQC 250
G+C +C
Sbjct: 291 QSEGHCTLEC 300
>AL357034-4|CAI15718.1| 613|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 613
Score = 142 bits (345), Expect = 1e-33
Identities = 84/250 (33%), Positives = 123/250 (49%), Gaps = 11/250 (4%)
Query: 5 LRPARINGTS-QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTPPG---LQ 60
L IN S D TV V+WA+ + G G +RLL P L
Sbjct: 126 LHTCDINDKSITDSTVRVIWAYHHE----DAGEAGPKYHDSNRGTKSLRLLNPEKTSVLS 181
Query: 61 KANGYQLRITNKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHME 120
A Y + N+D+ +P DTTYWC++ ++P F + HH+++ E I G+E LVHH+
Sbjct: 182 TALPY-FDLVNQDVPIPNKDTTYWCQMFKIPVF--QEKHHVIKVEPVIQRGHESLVHHIL 238
Query: 121 VFYCDEDPHKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKA 180
++ C + + + C+ P +C V AWA+G F+YP GL LG P
Sbjct: 239 LYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLD 298
Query: 181 NKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAF 240
YV+LEVHY+NP + +D+SG+ L+ T R YDA ++E GL + IP F
Sbjct: 299 PHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEF 358
Query: 241 PLTGYCIPQC 250
G+C +C
Sbjct: 359 QSEGHCTLEC 368
>AL357034-1|CAI15715.1| 545|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 545
Score = 142 bits (345), Expect = 1e-33
Identities = 84/250 (33%), Positives = 123/250 (49%), Gaps = 11/250 (4%)
Query: 5 LRPARINGTS-QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTPPG---LQ 60
L IN S D TV V+WA+ + G G +RLL P L
Sbjct: 58 LHTCDINDKSITDSTVRVIWAYHHE----DAGEAGPKYHDSNRGTKSLRLLNPEKTSVLS 113
Query: 61 KANGYQLRITNKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHME 120
A Y + N+D+ +P DTTYWC++ ++P F + HH+++ E I G+E LVHH+
Sbjct: 114 TALPY-FDLVNQDVPIPNKDTTYWCQMFKIPVF--QEKHHVIKVEPVIQRGHESLVHHIL 170
Query: 121 VFYCDEDPHKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKA 180
++ C + + + C+ P +C V AWA+G F+YP GL LG P
Sbjct: 171 LYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLD 230
Query: 181 NKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAF 240
YV+LEVHY+NP + +D+SG+ L+ T R YDA ++E GL + IP F
Sbjct: 231 PHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEF 290
Query: 241 PLTGYCIPQC 250
G+C +C
Sbjct: 291 QSEGHCTLEC 300
>AL023578-2|CAI19938.1| 613|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 613
Score = 142 bits (345), Expect = 1e-33
Identities = 84/250 (33%), Positives = 123/250 (49%), Gaps = 11/250 (4%)
Query: 5 LRPARINGTS-QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTPPG---LQ 60
L IN S D TV V+WA+ + G G +RLL P L
Sbjct: 126 LHTCDINDKSITDSTVRVIWAYHHE----DAGEAGPKYHDSNRGTKSLRLLNPEKTSVLS 181
Query: 61 KANGYQLRITNKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHME 120
A Y + N+D+ +P DTTYWC++ ++P F + HH+++ E I G+E LVHH+
Sbjct: 182 TALPY-FDLVNQDVPIPNKDTTYWCQMFKIPVF--QEKHHVIKVEPVIQRGHESLVHHIL 238
Query: 121 VFYCDEDPHKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKA 180
++ C + + + C+ P +C V AWA+G F+YP GL LG P
Sbjct: 239 LYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLD 298
Query: 181 NKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAF 240
YV+LEVHY+NP + +D+SG+ L+ T R YDA ++E GL + IP F
Sbjct: 299 PHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEF 358
Query: 241 PLTGYCIPQC 250
G+C +C
Sbjct: 359 QSEGHCTLEC 368
>AL023578-1|CAI19937.1| 545|Homo sapiens monooxygenase, DBH-like 1
protein.
Length = 545
Score = 142 bits (345), Expect = 1e-33
Identities = 84/250 (33%), Positives = 123/250 (49%), Gaps = 11/250 (4%)
Query: 5 LRPARINGTS-QDGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTPPG---LQ 60
L IN S D TV V+WA+ + G G +RLL P L
Sbjct: 58 LHTCDINDKSITDSTVRVIWAYHHE----DAGEAGPKYHDSNRGTKSLRLLNPEKTSVLS 113
Query: 61 KANGYQLRITNKDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHME 120
A Y + N+D+ +P DTTYWC++ ++P F + HH+++ E I G+E LVHH+
Sbjct: 114 TALPY-FDLVNQDVPIPNKDTTYWCQMFKIPVF--QEKHHVIKVEPVIQRGHESLVHHIL 170
Query: 121 VFYCDEDPHKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKA 180
++ C + + + C+ P +C V AWA+G F+YP GL LG P
Sbjct: 171 LYQCSNNFNDSVLESGHECYHPNMPDAFLTCETVIFAWAIGGEGFSYPPHVGLSLGTPLD 230
Query: 181 NKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAIMELGLEYTDKMAIPGEQKAF 240
YV+LEVHY+NP + +D+SG+ L+ T R YDA ++E GL + IP F
Sbjct: 231 PHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGVIEAGLWVSLFHTIPPGMPEF 290
Query: 241 PLTGYCIPQC 250
G+C +C
Sbjct: 291 QSEGHCTLEC 300
>BC108283-1|AAI08284.1| 147|Homo sapiens calcium regulated heat
stable protein 1, 24kDa protein.
Length = 147
Score = 117 bits (281), Expect = 7e-26
Identities = 58/113 (51%), Positives = 68/113 (60%), Gaps = 2/113 (1%)
Query: 236 EQKAFPLTGYCIPQCTGVTFMIIYRSE-RALGNPLETGKIKTFCREKGHGFVKPEKGGED 294
E+ PL G +P + + RA P+ G K FCR KGHGF+ P GG D
Sbjct: 28 ERSPSPLRGNVVPSPLPTRRTRTFSATVRASQGPVYKGVCKCFCRSKGHGFITPADGGPD 87
Query: 295 IFLHISDIEGEYVPLPGDEVIYRLCPIPPKFEKFQAVHVRIIHLTP-EKHVKW 346
IFLHISD+EGEYVP+ GDEV Y++C IPPK EK QAV V I HL P KH W
Sbjct: 88 IFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKHETW 140
>BC003366-1|AAH03366.1| 147|Homo sapiens calcium regulated heat
stable protein 1, 24kDa protein.
Length = 147
Score = 117 bits (281), Expect = 7e-26
Identities = 58/113 (51%), Positives = 68/113 (60%), Gaps = 2/113 (1%)
Query: 236 EQKAFPLTGYCIPQCTGVTFMIIYRSE-RALGNPLETGKIKTFCREKGHGFVKPEKGGED 294
E+ PL G +P + + RA P+ G K FCR KGHGF+ P GG D
Sbjct: 28 ERSPSPLRGNVVPSPLPTRRTRTFSATVRASQGPVYKGVCKCFCRSKGHGFITPADGGPD 87
Query: 295 IFLHISDIEGEYVPLPGDEVIYRLCPIPPKFEKFQAVHVRIIHLTP-EKHVKW 346
IFLHISD+EGEYVP+ GDEV Y++C IPPK EK QAV V I HL P KH W
Sbjct: 88 IFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKHETW 140
>AF115345-1|AAD25021.1| 147|Homo sapiens calcium-regulated heat
stable protein CRHSP-24 protein.
Length = 147
Score = 116 bits (278), Expect = 2e-25
Identities = 58/113 (51%), Positives = 68/113 (60%), Gaps = 2/113 (1%)
Query: 236 EQKAFPLTGYCIPQCTGVTFMIIYRSE-RALGNPLETGKIKTFCREKGHGFVKPEKGGED 294
E+ PL G +P + + RA P+ G K FCR KGHGF+ P GG D
Sbjct: 28 ERSPSPLRGNVVPSPLPTRRTRTFSATVRASQVPVYKGVCKCFCRSKGHGFITPADGGPD 87
Query: 295 IFLHISDIEGEYVPLPGDEVIYRLCPIPPKFEKFQAVHVRIIHLTP-EKHVKW 346
IFLHISD+EGEYVP+ GDEV Y++C IPPK EK QAV V I HL P KH W
Sbjct: 88 IFLHISDVEGEYVPVEGDEVTYKMCSIPPKNEKLQAVEVVITHLAPGTKHETW 140
>CR456457-1|CAG30343.1| 153|Homo sapiens dJ347H13.2 protein.
Length = 153
Score = 111 bits (266), Expect = 5e-24
Identities = 49/85 (57%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
Query: 263 RALGNPLETGKIKTFCREKGHGFVKPEKGGEDIFLHISDIEGEYVPLPGDEVIYRLCPIP 322
RA P+ G K F R +GHGF+ PE G EDIF+H+SDIEGEYVP+ GDEV Y++CPIP
Sbjct: 62 RASAGPVFKGVCKQFSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKMCPIP 121
Query: 323 PKFEKFQAVHVRIIHLTPE-KHVKW 346
PK +KFQAV V + L P H W
Sbjct: 122 PKNQKFQAVEVVLTQLAPHTPHETW 146
>BC067113-1|AAH67113.1| 153|Homo sapiens CSDC2 protein protein.
Length = 153
Score = 111 bits (266), Expect = 5e-24
Identities = 49/85 (57%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
Query: 263 RALGNPLETGKIKTFCREKGHGFVKPEKGGEDIFLHISDIEGEYVPLPGDEVIYRLCPIP 322
RA P+ G K F R +GHGF+ PE G EDIF+H+SDIEGEYVP+ GDEV Y++CPIP
Sbjct: 62 RASAGPVFKGVCKQFSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKMCPIP 121
Query: 323 PKFEKFQAVHVRIIHLTPE-KHVKW 346
PK +KFQAV V + L P H W
Sbjct: 122 PKNQKFQAVEVVLTQLAPHTPHETW 146
>AL023553-5|CAB46024.1| 153|Homo sapiens protein ( Human DNA
sequence from clone RP3-347H13 on chromosome 22. ).
Length = 153
Score = 111 bits (266), Expect = 5e-24
Identities = 49/85 (57%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
Query: 263 RALGNPLETGKIKTFCREKGHGFVKPEKGGEDIFLHISDIEGEYVPLPGDEVIYRLCPIP 322
RA P+ G K F R +GHGF+ PE G EDIF+H+SDIEGEYVP+ GDEV Y++CPIP
Sbjct: 62 RASAGPVFKGVCKQFSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKMCPIP 121
Query: 323 PKFEKFQAVHVRIIHLTPE-KHVKW 346
PK +KFQAV V + L P H W
Sbjct: 122 PKNQKFQAVEVVLTQLAPHTPHETW 146
>AB027011-1|BAA84704.1| 153|Homo sapiens RNA-binding protein PIPPin
protein.
Length = 153
Score = 111 bits (266), Expect = 5e-24
Identities = 49/85 (57%), Positives = 59/85 (69%), Gaps = 1/85 (1%)
Query: 263 RALGNPLETGKIKTFCREKGHGFVKPEKGGEDIFLHISDIEGEYVPLPGDEVIYRLCPIP 322
RA P+ G K F R +GHGF+ PE G EDIF+H+SDIEGEYVP+ GDEV Y++CPIP
Sbjct: 62 RASAGPVFKGVCKQFSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKMCPIP 121
Query: 323 PKFEKFQAVHVRIIHLTPE-KHVKW 346
PK +KFQAV V + L P H W
Sbjct: 122 PKNQKFQAVEVVLTQLAPHTPHETW 146
>AL365494-2|CAI13353.1| 244|Homo sapiens dopamine beta-hydroxylase
(dopamine beta-monooxygenase) protein.
Length = 244
Score = 90.2 bits (214), Expect = 9e-18
Identities = 53/151 (35%), Positives = 82/151 (54%), Gaps = 11/151 (7%)
Query: 16 DGTVHVVWAHGIDKLFSSKGLCLTCTVPQRHGFVRVRLLTP----PGLQKANGYQLRITN 71
DGTVH+V+ +++ F S + G RV+LL P P L ++ + +
Sbjct: 100 DGTVHLVYGI-LEEPFRSLEAINGSGLQM--GLQRVQLLKPNIPEPELP-SDACTMEVQA 155
Query: 72 KDLKVPGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDPHKE 131
++++P +TTYWC + LP+ + HHI+++E +T GNE LVHHMEVF C +
Sbjct: 156 PNIQIPSQETTYWCYIKELPKGFSR--HHIIKYEPIVTKGNEALVHHMEVFQCAPE-MDS 212
Query: 132 MPAYEGNCFAAERPAITKSCSKVKAAWAMGA 162
+P + G C + +P C V AAWA+GA
Sbjct: 213 VPHFSGPCDSKMKPDRLNYCRHVLAAWALGA 243
>AL080058-1|CAB45692.1| 335|Homo sapiens hypothetical protein
protein.
Length = 335
Score = 72.9 bits (171), Expect = 2e-12
Identities = 36/90 (40%), Positives = 49/90 (54%)
Query: 161 GAPPFTYPKEAGLPLGGPKANKYVMLEVHYNNPELRKDWVDSSGIVLYITGRKRTYDAAI 220
G F+YP GL LG P YV+LEVHY+NP + +D+SG+ L+ T R YDA +
Sbjct: 1 GGEGFSYPPHVGLSLGTPLDPHYVLLEVHYDNPTYEEGLIDNSGLRLFYTMDIRKYDAGV 60
Query: 221 MELGLEYTDKMAIPGEQKAFPLTGYCIPQC 250
+E GL + IP F G+C +C
Sbjct: 61 IEAGLWVSLFHTIPPGMPEFQSEGHCTLEC 90
>S75038-1|AAB32776.1| 905|Homo sapiens pancreatic peptidylglycine
alpha-amidating monooxygenase protein.
Length = 905
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 18/143 (12%)
Query: 73 DLKVPG----DDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDP 128
D+++PG TY+C +R+P + ++ F+ + VHHM +F C+
Sbjct: 60 DIRMPGVTPKQSDTYFCMSMRIP---VDEEAFVIDFKPRASMDT---VHHMLLFGCN--- 110
Query: 129 HKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEV 188
MP+ G+ + + T + + AWA APP PK G +GG +KY +L+V
Sbjct: 111 ---MPSSTGSYWFCDEGTCTDKAN-ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQV 166
Query: 189 HYNN-PELRKDWVDSSGIVLYIT 210
HY + R + D SG+ L++T
Sbjct: 167 HYGDISAFRDNNKDCSGVSLHLT 189
>S75037-1|AAB32775.1| 971|Homo sapiens pancreatic peptidylglycine
alpha-amidating monooxygenase protein.
Length = 971
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 18/143 (12%)
Query: 73 DLKVPG----DDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDP 128
D+++PG TY+C +R+P + ++ F+ + VHHM +F C+
Sbjct: 60 DIRMPGVTPKQSDTYFCMSMRIP---VDEEAFVIDFKPRASMDT---VHHMLLFGCN--- 110
Query: 129 HKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEV 188
MP+ G+ + + T + + AWA APP PK G +GG +KY +L+V
Sbjct: 111 ---MPSSTGSYWFCDEGTCTDKAN-ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQV 166
Query: 189 HYNN-PELRKDWVDSSGIVLYIT 210
HY + R + D SG+ L++T
Sbjct: 167 HYGDISAFRDNNKDCSGVSLHLT 189
>M37721-1|AAA36414.1| 974|Homo sapiens peptidylglycine
alpha-amidating monooxygenase protein.
Length = 974
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 18/143 (12%)
Query: 73 DLKVPG----DDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDP 128
D+++PG TY+C +R+P + ++ F+ + VHHM +F C+
Sbjct: 60 DIRMPGVTPKQSDTYFCMSMRIP---VDEEAFVIDFKPRASMDT---VHHMLLFGCN--- 110
Query: 129 HKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEV 188
MP+ G+ + + T + + AWA APP PK G +GG +KY +L+V
Sbjct: 111 ---MPSSTGSYWFCDEGTCTDKAN-ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQV 166
Query: 189 HYNN-PELRKDWVDSSGIVLYIT 210
HY + R + D SG+ L++T
Sbjct: 167 HYGDISAFRDNNKDCSGVSLHLT 189
>BT007419-1|AAP36087.1| 866|Homo sapiens peptidylglycine
alpha-amidating monooxygenase protein.
Length = 866
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 18/143 (12%)
Query: 73 DLKVPG----DDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDP 128
D+++PG TY+C +R+P + ++ F+ + VHHM +F C+
Sbjct: 60 DIRMPGVTPKQSDTYFCMSMRIP---VDEEAFVIDFKPRASMDT---VHHMLLFGCN--- 110
Query: 129 HKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEV 188
MP+ G+ + + T + + AWA APP PK G +GG +KY +L+V
Sbjct: 111 ---MPSSTGSYWFCDEGTCTDKAN-ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQV 166
Query: 189 HYNN-PELRKDWVDSSGIVLYIT 210
HY + R + D SG+ L++T
Sbjct: 167 HYGDISAFRDNNKDCSGVSLHLT 189
>BC018127-1|AAH18127.1| 866|Homo sapiens peptidylglycine
alpha-amidating monooxygenase protein.
Length = 866
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 18/143 (12%)
Query: 73 DLKVPG----DDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDP 128
D+++PG TY+C +R+P + ++ F+ + VHHM +F C+
Sbjct: 60 DIRMPGVTPKQSDTYFCMSMRIP---VDEEAFVIDFKPRASMDT---VHHMLLFGCN--- 110
Query: 129 HKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEV 188
MP+ G+ + + T + + AWA APP PK G +GG +KY +L+V
Sbjct: 111 ---MPSSTGSYWFCDEGTCTDKAN-ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQV 166
Query: 189 HYNN-PELRKDWVDSSGIVLYIT 210
HY + R + D SG+ L++T
Sbjct: 167 HYGDISAFRDNNKDCSGVSLHLT 189
>AB095007-1|BAC22594.1| 973|Homo sapiens peptidylglycine
alpha-amidating monooxygenase protein.
Length = 973
Score = 62.9 bits (146), Expect = 2e-09
Identities = 42/143 (29%), Positives = 70/143 (48%), Gaps = 18/143 (12%)
Query: 73 DLKVPG----DDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDP 128
D+++PG TY+C +R+P + ++ F+ + VHHM +F C+
Sbjct: 60 DIRMPGVTPKQSDTYFCMSMRIP---VDEEAFVIDFKPRASMDT---VHHMLLFGCN--- 110
Query: 129 HKEMPAYEGNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEV 188
MP+ G+ + + T + + AWA APP PK G +GG +KY +L+V
Sbjct: 111 ---MPSSTGSYWFCDEGTCTDKAN-ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQV 166
Query: 189 HYNN-PELRKDWVDSSGIVLYIT 210
HY + R + D SG+ L++T
Sbjct: 167 HYGDISAFRDNNKDCSGVSLHLT 189
>AF010472-1|AAD01439.1| 825|Homo sapiens alpha-amidating
monooxygenase protein.
Length = 825
Score = 62.1 bits (144), Expect = 3e-09
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 14/135 (10%)
Query: 77 PGDDTTYWCKVVRLPEFVTSKVHHIVQFESTITPGNEGLVHHMEVFYCDEDPHKEMPAYE 136
P TY+C +R+P + ++ F+ + VHHM +F C+ MP+
Sbjct: 6 PKQSDTYFCMSMRIP---VDEEAFVIDFKPRASMDT---VHHMLLFGCN------MPSST 53
Query: 137 GNCFAAERPAITKSCSKVKAAWAMGAPPFTYPKEAGLPLGGPKANKYVMLEVHYNN-PEL 195
G+ + + T + + AWA APP PK G +GG +KY +L+VHY +
Sbjct: 54 GSYWFCDEGTCTDKAN-ILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAF 112
Query: 196 RKDWVDSSGIVLYIT 210
R + D SG+ L++T
Sbjct: 113 RDNNKDCSGVSLHLT 127
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.140 0.447
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 62,686,519
Number of Sequences: 224733
Number of extensions: 2906932
Number of successful extensions: 7551
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 7502
Number of HSP's gapped (non-prelim): 29
length of query: 351
length of database: 73,234,838
effective HSP length: 91
effective length of query: 260
effective length of database: 52,784,135
effective search space: 13723875100
effective search space used: 13723875100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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