Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005262-TA|BGIBMGA005262-PA|IPR005956|4-
hydroxyphenylpyruvate dioxygenase, IPR004360|Glyoxalase/bleomycin
resistance protein/dioxygenase
(366 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X72389-1|CAA51082.1| 393|Homo sapiens 4-hydroxyphenylpyruvate d... 462 e-130
D31628-1|BAA06498.1| 393|Homo sapiens 4-hydroxyphenylpyruvic ac... 462 e-130
BC024287-1|AAH24287.1| 393|Homo sapiens 4-hydroxyphenylpyruvate... 462 e-130
U29895-1|AAC73008.1| 393|Homo sapiens 4-hydroxyphenylpyruvate-d... 461 e-129
BC007293-1|AAH07293.1| 371|Homo sapiens 4-hydroxyphenylpyruvate... 85 3e-16
AL359540-1|CAI21712.1| 371|Homo sapiens novel protein protein. 85 3e-16
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 31 6.4
AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-... 31 6.4
AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein. 31 6.4
BC111944-1|AAI11945.1| 304|Homo sapiens family with sequence si... 31 8.5
BC093665-1|AAH93665.1| 304|Homo sapiens family with sequence si... 31 8.5
AK126284-1|BAC86515.1| 304|Homo sapiens n 2 (Gab2). protein. 31 8.5
>X72389-1|CAA51082.1| 393|Homo sapiens 4-hydroxyphenylpyruvate
dioxygenase protein.
Length = 393
Score = 462 bits (1139), Expect = e-130
Identities = 212/356 (59%), Positives = 269/356 (75%), Gaps = 1/356 (0%)
Query: 1 MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 60
MTTY+DKG KP+ GRFL F VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1 MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
Query: 61 AVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 120
++ KI+FV + P E + + HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61 VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
Query: 121 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQLLE-KDPISKYLPKVEINF 179
W E+D++G V+ A L+TYG THTLV++ Y G FLPGY+ DP+ LPK +
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM 180
Query: 180 IDHIVGNQPENEMEEAASWYERCLQFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPI 239
IDHIVGNQP+ EM A+ WY + LQFHRFWSVDD QV TEYS+LRS+V+AN+EE++K+PI
Sbjct: 181 IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI 240
Query: 240 NEPAAGKRKSQIQEYVEYHGGAGVQHIAINTEDIITAIENLRERGVEFLSIPSKYYNLIR 299
NEPA GK+KSQIQEYV+Y+GGAGVQHIA+ TEDIITAI +LRERG+EFLS+PS YY +R
Sbjct: 241 NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLR 300
Query: 300 ERLKQSKVRVAESIDVLERXXXXXXXXXXXXXXQIFTKNTQDRPTLFLEVIQRRNH 355
E+LK +K++V E+ID LE QIFTK QDRPTLFLEVIQR NH
Sbjct: 301 EKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNH 356
>D31628-1|BAA06498.1| 393|Homo sapiens 4-hydroxyphenylpyruvic acid
dioxgenase (HPD) protein.
Length = 393
Score = 462 bits (1139), Expect = e-130
Identities = 212/356 (59%), Positives = 269/356 (75%), Gaps = 1/356 (0%)
Query: 1 MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 60
MTTY+DKG KP+ GRFL F VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1 MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
Query: 61 AVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 120
++ KI+FV + P E + + HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61 VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
Query: 121 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQLLE-KDPISKYLPKVEINF 179
W E+D++G V+ A L+TYG THTLV++ Y G FLPGY+ DP+ LPK +
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM 180
Query: 180 IDHIVGNQPENEMEEAASWYERCLQFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPI 239
IDHIVGNQP+ EM A+ WY + LQFHRFWSVDD QV TEYS+LRS+V+AN+EE++K+PI
Sbjct: 181 IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI 240
Query: 240 NEPAAGKRKSQIQEYVEYHGGAGVQHIAINTEDIITAIENLRERGVEFLSIPSKYYNLIR 299
NEPA GK+KSQIQEYV+Y+GGAGVQHIA+ TEDIITAI +LRERG+EFLS+PS YY +R
Sbjct: 241 NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLR 300
Query: 300 ERLKQSKVRVAESIDVLERXXXXXXXXXXXXXXQIFTKNTQDRPTLFLEVIQRRNH 355
E+LK +K++V E+ID LE QIFTK QDRPTLFLEVIQR NH
Sbjct: 301 EKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNH 356
>BC024287-1|AAH24287.1| 393|Homo sapiens 4-hydroxyphenylpyruvate
dioxygenase protein.
Length = 393
Score = 462 bits (1139), Expect = e-130
Identities = 212/356 (59%), Positives = 269/356 (75%), Gaps = 1/356 (0%)
Query: 1 MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 60
MTTY+DKG KP+ GRFL F VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1 MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
Query: 61 AVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 120
++ KI+FV + P E + + HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61 VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
Query: 121 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQLLE-KDPISKYLPKVEINF 179
W E+D++G V+ A L+TYG THTLV++ Y G FLPGY+ DP+ LPK +
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM 180
Query: 180 IDHIVGNQPENEMEEAASWYERCLQFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPI 239
IDHIVGNQP+ EM A+ WY + LQFHRFWSVDD QV TEYS+LRS+V+AN+EE++K+PI
Sbjct: 181 IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI 240
Query: 240 NEPAAGKRKSQIQEYVEYHGGAGVQHIAINTEDIITAIENLRERGVEFLSIPSKYYNLIR 299
NEPA GK+KSQIQEYV+Y+GGAGVQHIA+ TEDIITAI +LRERG+EFLS+PS YY +R
Sbjct: 241 NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLR 300
Query: 300 ERLKQSKVRVAESIDVLERXXXXXXXXXXXXXXQIFTKNTQDRPTLFLEVIQRRNH 355
E+LK +K++V E+ID LE QIFTK QDRPTLFLEVIQR NH
Sbjct: 301 EKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNH 356
>U29895-1|AAC73008.1| 393|Homo sapiens
4-hydroxyphenylpyruvate-dioxygenase protein.
Length = 393
Score = 461 bits (1137), Expect = e-129
Identities = 212/356 (59%), Positives = 269/356 (75%), Gaps = 1/356 (0%)
Query: 1 MTTYTDKGRKPDDGRFLAFDHVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSH 60
MTTY+DKG KP+ GRFL F VTFWV NAKQAAS+Y ++ GFEPLAY GLETGSR++ SH
Sbjct: 1 MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
Query: 61 AVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKD 120
++ KI+FV + P E + + HGD VKD+AF+VE+ DYI++ AR++GAK++++
Sbjct: 61 VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
Query: 121 LWEEKDQYGVVRMATLKTYGSNTHTLVDRSKYTGPFLPGYQLLE-KDPISKYLPKVEINF 179
W E+D++G V+ A L+TYG THTLV++ Y G FLPGY+ DP+ LPK +
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEPPAFMDPLLPKLPKCSLEM 180
Query: 180 IDHIVGNQPENEMEEAASWYERCLQFHRFWSVDDKQVCTEYSALRSVVMANWEETVKVPI 239
IDHIVGNQP+ EM A+ WY + LQFHRFWSVDD QV TEYS+LRS+V+AN+EE++K+PI
Sbjct: 181 IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI 240
Query: 240 NEPAAGKRKSQIQEYVEYHGGAGVQHIAINTEDIITAIENLRERGVEFLSIPSKYYNLIR 299
NEPA GK+KSQIQEYV+Y+GGAGVQHIA+ TEDIITAI +LRERG+EFLS+PS YY +R
Sbjct: 241 NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLR 300
Query: 300 ERLKQSKVRVAESIDVLERXXXXXXXXXXXXXXQIFTKNTQDRPTLFLEVIQRRNH 355
E+LK +K++V E+ID LE QIFTK QDRPTLFLEVIQR NH
Sbjct: 301 EKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNH 356
>BC007293-1|AAH07293.1| 371|Homo sapiens 4-hydroxyphenylpyruvate
dioxygenase-like protein.
Length = 371
Score = 85.4 bits (202), Expect = 3e-16
Identities = 86/347 (24%), Positives = 148/347 (42%), Gaps = 26/347 (7%)
Query: 21 HVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSHAVRMNKIIFVFQAQYEPVET 80
H+ F V + A FGF+PLA ++ G RQ+ A+R +F+ E
Sbjct: 10 HIAFHVPAGQPLARNLQRLFGFQPLASREVD-GWRQL---ALRSGDAVFLVNEGAGSGEP 65
Query: 81 EFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKDLWEEKDQYGVVRMATLKT-Y 139
+ + ++ F V + G V +D G A + +
Sbjct: 66 LYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPA 125
Query: 140 GSNTHTLVDRSKYTGPFLPGYQLLEKDPISKYLPKVEINFIDHIVGNQPENEMEEAASWY 199
G + TL++R+ Y GPFLPG++ + P ++ +V DH+ W+
Sbjct: 126 GILSLTLLERAGYRGPFLPGFRPVSSAPGPGWVSRV-----DHLTLACTPGSSPTLLRWF 180
Query: 200 ERCLQF-HRFWSV-DDKQVCTEYSA------LRSVVM----ANWEETVKVPINEPAAGKR 247
CL F H S +D ++ E +A LR + + T+ + + P A R
Sbjct: 181 HDCLGFCHLPLSPGEDPELGLEMTAGFGLGGLRLTALQAQPGSIVPTLVLAESLPGATTR 240
Query: 248 KSQIQEYVEYHGGAGVQHIAINTEDIITAIENLRERGVEFLSIPSKYYNLIRERLKQSKV 307
+ Q+++++ H G G+QH+ + T +I+ A E + G +FL+ P YY ++ K+ ++
Sbjct: 241 QDQVEQFLARHKGPGLQHVGLYTPNIVEATEGVATAGGQFLAPPGAYY---QQPGKERQI 297
Query: 308 RVA-ESIDVLERXXXXXXXXXXXXXXQIFTKNTQDRPTLFLEVIQRR 353
R A +L R Q+FTK+ T FLE+IQR+
Sbjct: 298 RAAGHEPHLLARQGILLDGDKGKFLLQVFTKSLFTEDTFFLELIQRQ 344
>AL359540-1|CAI21712.1| 371|Homo sapiens novel protein protein.
Length = 371
Score = 85.4 bits (202), Expect = 3e-16
Identities = 86/347 (24%), Positives = 148/347 (42%), Gaps = 26/347 (7%)
Query: 21 HVTFWVSNAKQAASYYVTRFGFEPLAYSGLETGSRQISSHAVRMNKIIFVFQAQYEPVET 80
H+ F V + A FGF+PLA ++ G RQ+ A+R +F+ E
Sbjct: 10 HIAFHVPAGQPLARNLQRLFGFQPLASREVD-GWRQL---ALRSGDAVFLVNEGAGSGEP 65
Query: 81 EFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVKDLWEEKDQYGVVRMATLKT-Y 139
+ + ++ F V + G V +D G A + +
Sbjct: 66 LYGLDPRHAVPSATNLCFDVADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPA 125
Query: 140 GSNTHTLVDRSKYTGPFLPGYQLLEKDPISKYLPKVEINFIDHIVGNQPENEMEEAASWY 199
G + TL++R+ Y GPFLPG++ + P ++ +V DH+ W+
Sbjct: 126 GILSLTLLERAGYRGPFLPGFRPVSSAPGPGWVSRV-----DHLTLACTPGSSPTLLRWF 180
Query: 200 ERCLQF-HRFWSV-DDKQVCTEYSA------LRSVVM----ANWEETVKVPINEPAAGKR 247
CL F H S +D ++ E +A LR + + T+ + + P A R
Sbjct: 181 HDCLGFCHLPLSPGEDPELGLEMTAGFGLGGLRLTALQAQPGSIVPTLVLAESLPGATTR 240
Query: 248 KSQIQEYVEYHGGAGVQHIAINTEDIITAIENLRERGVEFLSIPSKYYNLIRERLKQSKV 307
+ Q+++++ H G G+QH+ + T +I+ A E + G +FL+ P YY ++ K+ ++
Sbjct: 241 QDQVEQFLARHKGPGLQHVGLYTPNIVEATEGVATAGGQFLAPPGAYY---QQPGKERQI 297
Query: 308 RVA-ESIDVLERXXXXXXXXXXXXXXQIFTKNTQDRPTLFLEVIQRR 353
R A +L R Q+FTK+ T FLE+IQR+
Sbjct: 298 RAAGHEPHLLARQGILLDGDKGKFLLQVFTKSLFTEDTFFLELIQRQ 344
>DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein.
Length = 2479
Score = 31.1 bits (67), Expect = 6.4
Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 48 SGLETGSRQISSHAVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYIL 107
S L +++S R +I + ++E ++ + H D VK V +VE+L Y+L
Sbjct: 1638 SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 1694
Query: 108 EYARKQGAKVVKDLWEEKD 126
+ ++K+ + +L +K+
Sbjct: 1695 DQSQKESQCLKSELQAQKE 1713
>AF273044-1|AAG34904.1| 761|Homo sapiens CTCL tumor antigen se2-2
protein.
Length = 761
Score = 31.1 bits (67), Expect = 6.4
Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 48 SGLETGSRQISSHAVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYIL 107
S L +++S R +I + ++E ++ + H D VK V +VE+L Y+L
Sbjct: 13 SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 69
Query: 108 EYARKQGAKVVKDLWEEKD 126
+ ++K+ + +L +K+
Sbjct: 70 DQSQKESQCLKSELQAQKE 88
>AB002371-1|BAA20828.2| 1540|Homo sapiens KIAA0373 protein.
Length = 1540
Score = 31.1 bits (67), Expect = 6.4
Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 48 SGLETGSRQISSHAVRMNKIIFVFQAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYIL 107
S L +++S R +I + ++E ++ + H D VK V +VE+L Y+L
Sbjct: 699 SSLLVKLKKVSQDLERQREITELKVKEFENIKLQLQEN---HEDEVKKVKAEVEDLKYLL 755
Query: 108 EYARKQGAKVVKDLWEEKD 126
+ ++K+ + +L +K+
Sbjct: 756 DQSQKESQCLKSELQAQKE 774
>BC111944-1|AAI11945.1| 304|Homo sapiens family with sequence
similarity 92, member B protein.
Length = 304
Score = 30.7 bits (66), Expect = 8.5
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 72 QAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVK 119
QAQ E +ET+ VN + ++G +K +++ ++ + KQ K+ K
Sbjct: 83 QAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQLEKLEK 130
>BC093665-1|AAH93665.1| 304|Homo sapiens family with sequence
similarity 92, member B protein.
Length = 304
Score = 30.7 bits (66), Expect = 8.5
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 72 QAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVK 119
QAQ E +ET+ VN + ++G +K +++ ++ + KQ K+ K
Sbjct: 83 QAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQLEKLEK 130
>AK126284-1|BAC86515.1| 304|Homo sapiens n 2 (Gab2). protein.
Length = 304
Score = 30.7 bits (66), Expect = 8.5
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 72 QAQYEPVETEFVNEVAIHGDFVKDVAFQVENLDYILEYARKQGAKVVK 119
QAQ E +ET+ VN + ++G +K +++ ++ + KQ K+ K
Sbjct: 83 QAQVERLETKVVNPLKLYGAQIKQTRAEIKKFKHVQNHEIKQLEKLEK 130
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.396
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 50,020,912
Number of Sequences: 224733
Number of extensions: 1923117
Number of successful extensions: 3449
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3426
Number of HSP's gapped (non-prelim): 14
length of query: 366
length of database: 73,234,838
effective HSP length: 91
effective length of query: 275
effective length of database: 52,784,135
effective search space: 14515637125
effective search space used: 14515637125
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
- SilkBase 1999-2023 -