Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005248-TA|BGIBMGA005248-PA|IPR002347|Glucose/ribitol
dehydrogenase, IPR002198|Short-chain dehydrogenase/reductase SDR
(254 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 146 5e-35
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 146 5e-35
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 95 2e-19
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 95 2e-19
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 87 4e-17
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 87 4e-17
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 87 6e-17
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 87 6e-17
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 81 5e-15
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 80 6e-15
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 79 1e-14
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 79 1e-14
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 79 1e-14
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 79 1e-14
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 79 1e-14
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 77 8e-14
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 77 8e-14
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 77 8e-14
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 77 8e-14
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 76 1e-13
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 75 2e-13
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 75 2e-13
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 75 2e-13
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 75 2e-13
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 75 2e-13
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 75 2e-13
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 75 2e-13
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 75 2e-13
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 74 4e-13
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 73 1e-12
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 73 1e-12
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 73 1e-12
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 73 1e-12
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 73 1e-12
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 71 5e-12
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 70 7e-12
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 70 7e-12
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 70 7e-12
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 70 7e-12
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 70 7e-12
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 70 7e-12
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 70 7e-12
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 70 7e-12
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 70 9e-12
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 70 9e-12
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 70 9e-12
AL162732-2|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 70 9e-12
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 69 2e-11
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 69 2e-11
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 67 6e-11
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 67 6e-11
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 67 6e-11
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 65 3e-10
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 65 3e-10
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 65 3e-10
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 65 3e-10
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 64 3e-10
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 64 3e-10
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 64 3e-10
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 64 3e-10
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 64 3e-10
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 63 8e-10
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 63 8e-10
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 63 8e-10
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 62 1e-09
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 61 4e-09
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 61 4e-09
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 61 4e-09
AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid ... 60 6e-09
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 60 6e-09
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 60 7e-09
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 60 7e-09
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 60 7e-09
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 60 7e-09
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 60 7e-09
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 60 7e-09
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 60 7e-09
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 60 7e-09
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 60 7e-09
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 59 1e-08
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 59 1e-08
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 59 1e-08
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 59 1e-08
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 59 1e-08
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 59 2e-08
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 59 2e-08
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 59 2e-08
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 59 2e-08
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 59 2e-08
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 59 2e-08
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 59 2e-08
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 59 2e-08
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 58 3e-08
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 58 3e-08
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 58 3e-08
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 58 4e-08
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 58 4e-08
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 58 4e-08
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 58 4e-08
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 56 9e-08
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 56 9e-08
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 56 9e-08
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 56 9e-08
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 56 9e-08
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 56 1e-07
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 56 2e-07
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 55 3e-07
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 55 3e-07
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 55 3e-07
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 54 4e-07
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 54 4e-07
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 54 4e-07
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 54 4e-07
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 54 4e-07
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 53 8e-07
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 53 1e-06
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 52 1e-06
AL023881-2|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 52 1e-06
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 52 1e-06
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 52 1e-06
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 52 1e-06
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 52 1e-06
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxyacyl-Coenzyme A de... 52 2e-06
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 52 2e-06
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 52 2e-06
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 52 2e-06
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 52 2e-06
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 52 2e-06
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 52 2e-06
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 52 2e-06
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 52 2e-06
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 52 2e-06
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 52 2e-06
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 52 2e-06
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 52 2e-06
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 52 3e-06
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 52 3e-06
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 52 3e-06
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 52 3e-06
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 52 3e-06
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 52 3e-06
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 52 3e-06
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 52 3e-06
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 52 3e-06
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 52 3e-06
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 52 3e-06
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 52 3e-06
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 52 3e-06
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 52 3e-06
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 52 3e-06
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 51 3e-06
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 51 3e-06
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 51 3e-06
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 51 3e-06
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 51 3e-06
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 51 3e-06
AL645940-11|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 51 3e-06
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 51 3e-06
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 51 5e-06
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 51 5e-06
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 51 5e-06
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 51 5e-06
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 51 5e-06
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 51 5e-06
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 50 6e-06
BC064525-1|AAH64525.1| 309|Homo sapiens retinal short chain deh... 50 8e-06
BC037219-1|AAH37219.2| 309|Homo sapiens retinal short chain deh... 50 8e-06
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 50 8e-06
AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens ... 50 1e-05
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 48 2e-05
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 48 2e-05
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 47 6e-05
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 47 7e-05
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 46 1e-04
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 46 1e-04
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 46 1e-04
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 46 1e-04
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 46 1e-04
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 46 1e-04
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 46 1e-04
Z97054-9|CAI42652.1| 252|Homo sapiens hydroxyacyl-Coenzyme A de... 44 4e-04
Z97054-7|CAI42651.1| 169|Homo sapiens hydroxyacyl-Coenzyme A de... 44 4e-04
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 44 4e-04
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 44 7e-04
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 43 0.001
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 43 0.001
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 43 0.001
M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid de... 43 0.001
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 43 0.001
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 43 0.001
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 43 0.001
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 43 0.001
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 43 0.001
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 43 0.001
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 43 0.001
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 43 0.001
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 43 0.001
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 43 0.001
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 43 0.001
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 43 0.001
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 43 0.001
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 42 0.002
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 42 0.002
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 42 0.002
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 42 0.002
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 42 0.002
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 42 0.002
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 42 0.002
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 42 0.003
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 42 0.003
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 41 0.004
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 41 0.004
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 41 0.004
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 41 0.004
BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein. 41 0.005
BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein. 41 0.005
AY313896-1|AAP83168.1| 234|Homo sapiens short-chain dehydrogena... 41 0.005
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 41 0.005
AY268351-1|AAP42285.1| 205|Homo sapiens short-chain dehydrogena... 41 0.005
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 40 0.006
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 40 0.006
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 40 0.006
AL023881-1|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 40 0.006
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 40 0.008
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 40 0.008
BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein. 40 0.008
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 40 0.008
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 40 0.008
AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase... 39 0.015
BC004331-1|AAH04331.1| 345|Homo sapiens HSDL2 protein protein. 39 0.020
AL162732-1|CAM17151.1| 345|Homo sapiens hydroxysteroid dehydrog... 39 0.020
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 38 0.026
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 38 0.026
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 36 0.10
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 36 0.10
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 36 0.10
AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein. 36 0.10
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 36 0.10
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 36 0.10
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 36 0.10
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 36 0.10
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 36 0.10
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 36 0.10
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 36 0.10
BC072434-1|AAH72434.1| 152|Homo sapiens HSD11B1L protein protein. 36 0.18
BC053546-1|AAH53546.1| 152|Homo sapiens hydroxysteroid (11-beta... 36 0.18
AY313895-1|AAP83167.1| 181|Homo sapiens short-chain dehydrogena... 36 0.18
AY268354-1|AAP42288.1| 152|Homo sapiens short-chain dehydrogena... 36 0.18
CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase... 35 0.32
BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase... 35 0.32
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 33 0.73
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 33 1.3
BC012536-1|AAH12536.1| 98|Homo sapiens HSD17B12 protein protein. 32 1.7
AL355001-1|CAI16178.1| 493|Homo sapiens zinc finger, MYM-type 5... 32 2.2
AL354808-2|CAI41001.1| 493|Homo sapiens zinc finger, MYM-type 5... 32 2.2
AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent 15-hydro... 31 3.0
AL137300-1|CAB70685.1| 204|Homo sapiens hypothetical protein pr... 31 5.2
AK097760-1|BAC05162.1| 824|Homo sapiens protein ( Homo sapiens ... 31 5.2
BC008746-1|AAH08746.1| 538|Homo sapiens CWF19L1 protein protein. 30 6.8
AK023984-1|BAB14754.1| 242|Homo sapiens protein ( Homo sapiens ... 30 6.8
AK001860-1|BAA91947.1| 538|Homo sapiens protein ( Homo sapiens ... 30 6.8
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 30 6.8
AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retin... 30 9.1
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 147 bits (355), Expect = 5e-35
Identities = 84/252 (33%), Positives = 139/252 (55%), Gaps = 7/252 (2%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQL 60
M+ W+++ A+VTGA GIGA + L++ G+ V+G T + L K + L
Sbjct: 6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAEC-KSAGYPGTL 64
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYG 120
IP +CD+SN+ D+ + F I + GVD+ +NNA + + + +G+ ++ +VN+
Sbjct: 65 IPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLA 124
Query: 121 LIACSRHAIDSMK--NKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
L C+R A SMK N GHI+N+NS+ GH + S V + Y A+K ++T T+ LR+
Sbjct: 125 LSICTREAYQSMKERNVDDGHIININSMSGHRVLPLS--VTHFYSATKYAVTALTEGLRQ 182
Query: 179 ELKMINSKIKITSVSPGIVKTGI-FKSAGVGFIDDAFFCDNSH-LTVKDVSEVILMILSS 236
EL+ + I+ T +SPG+V+T FK A + L +DV+E ++ +LS+
Sbjct: 183 ELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLST 242
Query: 237 PRTVNITEIIFR 248
P + I +I R
Sbjct: 243 PAHIQIGDIQMR 254
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 147 bits (355), Expect = 5e-35
Identities = 84/252 (33%), Positives = 139/252 (55%), Gaps = 7/252 (2%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQL 60
M+ W+++ A+VTGA GIGA + L++ G+ V+G T + L K + L
Sbjct: 6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAEC-KSAGYPGTL 64
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYG 120
IP +CD+SN+ D+ + F I + GVD+ +NNA + + + +G+ ++ +VN+
Sbjct: 65 IPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLA 124
Query: 121 LIACSRHAIDSMK--NKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
L C+R A SMK N GHI+N+NS+ GH + S V + Y A+K ++T T+ LR+
Sbjct: 125 LSICTREAYQSMKERNVDDGHIININSMSGHRVLPLS--VTHFYSATKYAVTALTEGLRQ 182
Query: 179 ELKMINSKIKITSVSPGIVKTGI-FKSAGVGFIDDAFFCDNSH-LTVKDVSEVILMILSS 236
EL+ + I+ T +SPG+V+T FK A + L +DV+E ++ +LS+
Sbjct: 183 ELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLST 242
Query: 237 PRTVNITEIIFR 248
P + I +I R
Sbjct: 243 PAHIQIGDIQMR 254
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 95.1 bits (226), Expect = 2e-19
Identities = 56/169 (33%), Positives = 94/169 (55%), Gaps = 6/169 (3%)
Query: 84 YGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMK--NKGKGHIV 141
+ GVD+ +NNA + + + +G+ ++ +VN+ L C+R A SMK N GHI+
Sbjct: 9 HSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHII 68
Query: 142 NVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGIVKTGI 201
N+NS+ GH + S V + Y A+K ++T T+ LR+EL+ + I+ T +SPG+V+T
Sbjct: 69 NINSMSGHRVLPLS--VTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQF 126
Query: 202 -FKSAGVGFIDDAFFCDNSH-LTVKDVSEVILMILSSPRTVNITEIIFR 248
FK A + L +DV+E ++ +LS+P + I +I R
Sbjct: 127 AFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMR 175
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 95.1 bits (226), Expect = 2e-19
Identities = 56/169 (33%), Positives = 94/169 (55%), Gaps = 6/169 (3%)
Query: 84 YGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMK--NKGKGHIV 141
+ GVD+ +NNA + + + +G+ ++ +VN+ L C+R A SMK N GHI+
Sbjct: 9 HSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHII 68
Query: 142 NVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGIVKTGI 201
N+NS+ GH + S V + Y A+K ++T T+ LR+EL+ + I+ T +SPG+V+T
Sbjct: 69 NINSMSGHRVLPLS--VTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQF 126
Query: 202 -FKSAGVGFIDDAFFCDNSH-LTVKDVSEVILMILSSPRTVNITEIIFR 248
FK A + L +DV+E ++ +LS+P + I +I R
Sbjct: 127 AFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMR 175
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 87.4 bits (207), Expect = 4e-17
Identities = 60/205 (29%), Positives = 102/205 (49%), Gaps = 16/205 (7%)
Query: 3 HWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIP 62
H K A+VTGA QGIG E L+ G V + D+ E L
Sbjct: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF- 60
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLI 122
+CD+++ L++ F +V +G +D+LVNNA + N ++ + +N+ +I
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112
Query: 123 ACSRHAIDSM--KNKGKGHIV-NVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREE 179
+ + +D M +N G+G I+ N++S+ G MP +PV Y ASK + FT++
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAG-LMPVAQQPV---YCASKHGIVGFTRSAALA 168
Query: 180 LKMINSKIKITSVSPGIVKTGIFKS 204
++NS +++ ++ PG V T I +S
Sbjct: 169 ANLMNSGVRLNAICPGFVNTAILES 193
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 87.4 bits (207), Expect = 4e-17
Identities = 60/205 (29%), Positives = 102/205 (49%), Gaps = 16/205 (7%)
Query: 3 HWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIP 62
H K A+VTGA QGIG E L+ G V + D+ E L
Sbjct: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF- 60
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLI 122
+CD+++ L++ F +V +G +D+LVNNA + N ++ + +N+ +I
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSVI 112
Query: 123 ACSRHAIDSM--KNKGKGHIV-NVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREE 179
+ + +D M +N G+G I+ N++S+ G MP +PV Y ASK + FT++
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAG-LMPVAQQPV---YCASKHGIVGFTRSAALA 168
Query: 180 LKMINSKIKITSVSPGIVKTGIFKS 204
++NS +++ ++ PG V T I +S
Sbjct: 169 ANLMNSGVRLNAICPGFVNTAILES 193
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 87.0 bits (206), Expect = 6e-17
Identities = 60/206 (29%), Positives = 106/206 (51%), Gaps = 18/206 (8%)
Query: 3 HWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFE-PTQAKLTPLFNLADKYSELNNQLI 61
H K A+VTGA QGIG E L+ G V + +A + L +++ I
Sbjct: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFI 61
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
+CD+++ L++ F +V +G +D+LVNNA + N ++ + +N+ +
Sbjct: 62 --QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSV 111
Query: 122 IACSRHAIDSM--KNKGKGHIV-NVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
I+ + +D M +N G+G I+ N++S+ G MP +PV Y ASK + FT++
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAG-LMPVAQQPV---YCASKHGIVGFTRSAAL 167
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKS 204
++NS +++ ++ PG V T I +S
Sbjct: 168 AANLMNSGVRLNAICPGFVNTAILES 193
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 87.0 bits (206), Expect = 6e-17
Identities = 60/206 (29%), Positives = 106/206 (51%), Gaps = 18/206 (8%)
Query: 3 HWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFE-PTQAKLTPLFNLADKYSELNNQLI 61
H K A+VTGA QGIG E L+ G V + +A + L +++ I
Sbjct: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFI 61
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
+CD+++ L++ F +V +G +D+LVNNA + N ++ + +N+ +
Sbjct: 62 --QCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVN--------NEKNWEKTLQINLVSV 111
Query: 122 IACSRHAIDSM--KNKGKGHIV-NVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
I+ + +D M +N G+G I+ N++S+ G MP +PV Y ASK + FT++
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAG-LMPVAQQPV---YCASKHGIVGFTRSAAL 167
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKS 204
++NS +++ ++ PG V T I +S
Sbjct: 168 AANLMNSGVRLNAICPGFVNTAILES 193
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 80.6 bits (190), Expect = 5e-15
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 17/247 (6%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAG--MTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC 63
+K V G +GIG + + + + G + VI AK +L +
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA--------GDLGGDHLAF 53
Query: 64 KCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIA 123
CD++ ++D++N FE + K G V+ LVN A I + G++ ED+ + + N+ G +
Sbjct: 54 SCDVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ A+ +M + G IVNV SI G +VY ASK + F++ L +E +
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVG----LKGNSGQSVYSASKGGLVGFSRALAKE--VA 167
Query: 184 NSKIKITSVSPGIVKTGIFKSAGVGFIDDAFFCDNSHLTVKDVSEVILMILSSPRTVNIT 243
KI++ V+PG V T + K + T+ +V+ ++ +L SP
Sbjct: 168 RKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETI-EVAHAVVFLLESPYITGHV 226
Query: 244 EIIFRGL 250
++ GL
Sbjct: 227 LVVDGGL 233
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 80.2 bits (189), Expect = 6e-15
Identities = 64/247 (25%), Positives = 112/247 (45%), Gaps = 17/247 (6%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAG--MTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC 63
+K V G +GIG + + + + G + VI AK +L +
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA--------GDLGGDHLAF 53
Query: 64 KCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIA 123
CD++ ++D++N FE + K G V+ LVN A I + G++ ED+ + + N+ G +
Sbjct: 54 SCDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ A+ +M + G IVNV SI G +VY ASK + F++ L +E +
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVG----LKGNSGQSVYSASKGGLVGFSRALAKE--VA 167
Query: 184 NSKIKITSVSPGIVKTGIFKSAGVGFIDDAFFCDNSHLTVKDVSEVILMILSSPRTVNIT 243
KI++ V+PG V T + K + T+ +V+ ++ +L SP
Sbjct: 168 RKKIRVNVVAPGFVHTDMTKDLKEEHLKKNIPLGRFGETI-EVAHAVVFLLESPYITGHV 226
Query: 244 EIIFRGL 250
++ GL
Sbjct: 227 LVVDGGL 233
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 79.0 bits (186), Expect = 1e-14
Identities = 56/204 (27%), Positives = 98/204 (48%), Gaps = 9/204 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFN-LADKYSELNNQLIP- 62
+N ++TGA G+G + + AG ++ L L L ++ P
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 63 -CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
D+++ + A I++ +G VD+LVNNA I G I ++ V++ N +G
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+A ++ + SM + +GHIV ++SI G S P + Y ASK + F LR E++
Sbjct: 171 VALTKALLPSMIKRRQGHIVAISSIQG----KMSIPFRSAYAASKHATQAFFDCLRAEME 226
Query: 182 MINSKIKITSVSPGIVKTGIFKSA 205
+I++T +SPG + T + +A
Sbjct: 227 QY--EIEVTVISPGYIHTNLSVNA 248
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 79.0 bits (186), Expect = 1e-14
Identities = 56/204 (27%), Positives = 98/204 (48%), Gaps = 9/204 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFN-LADKYSELNNQLIP- 62
+N ++TGA G+G + + AG ++ L L L ++ P
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 63 -CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
D+++ + A I++ +G VD+LVNNA I G I ++ V++ N +G
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+A ++ + SM + +GHIV ++SI G S P + Y ASK + F LR E++
Sbjct: 171 VALTKALLPSMIKRRQGHIVAISSIQG----KMSIPFRSAYAASKHATQAFFDCLRAEME 226
Query: 182 MINSKIKITSVSPGIVKTGIFKSA 205
+I++T +SPG + T + +A
Sbjct: 227 QY--EIEVTVISPGYIHTNLSVNA 248
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 79.0 bits (186), Expect = 1e-14
Identities = 56/204 (27%), Positives = 98/204 (48%), Gaps = 9/204 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFN-LADKYSELNNQLIP- 62
+N ++TGA G+G + + AG ++ L L L ++ P
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 63 -CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
D+++ + A I++ +G VD+LVNNA I G I ++ V++ N +G
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+A ++ + SM + +GHIV ++SI G S P + Y ASK + F LR E++
Sbjct: 171 VALTKALLPSMIKRRQGHIVAISSIQG----KMSIPFRSAYAASKHATQAFFDCLRAEME 226
Query: 182 MINSKIKITSVSPGIVKTGIFKSA 205
+I++T +SPG + T + +A
Sbjct: 227 QY--EIEVTVISPGYIHTNLSVNA 248
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 79.0 bits (186), Expect = 1e-14
Identities = 56/204 (27%), Positives = 98/204 (48%), Gaps = 9/204 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFN-LADKYSELNNQLIP- 62
+N ++TGA G+G + + AG ++ L L L ++ P
Sbjct: 36 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 95
Query: 63 -CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
D+++ + A I++ +G VD+LVNNA I G I ++ V++ N +G
Sbjct: 96 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 155
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+A ++ + SM + +GHIV ++SI G S P + Y ASK + F LR E++
Sbjct: 156 VALTKALLPSMIKRRQGHIVAISSIQG----KMSIPFRSAYAASKHATQAFFDCLRAEME 211
Query: 182 MINSKIKITSVSPGIVKTGIFKSA 205
+I++T +SPG + T + +A
Sbjct: 212 QY--EIEVTVISPGYIHTNLSVNA 233
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 79.0 bits (186), Expect = 1e-14
Identities = 56/204 (27%), Positives = 98/204 (48%), Gaps = 9/204 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFN-LADKYSELNNQLIP- 62
+N ++TGA G+G + + AG ++ L L L ++ P
Sbjct: 56 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 115
Query: 63 -CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
D+++ + A I++ +G VD+LVNNA I G I ++ V++ N +G
Sbjct: 116 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 175
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+A ++ + SM + +GHIV ++SI G S P + Y ASK + F LR E++
Sbjct: 176 VALTKALLPSMIKRRQGHIVAISSIQG----KMSIPFRSAYAASKHATQAFFDCLRAEME 231
Query: 182 MINSKIKITSVSPGIVKTGIFKSA 205
+I++T +SPG + T + +A
Sbjct: 232 QY--EIEVTVISPGYIHTNLSVNA 253
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 76.6 bits (180), Expect = 8e-14
Identities = 59/199 (29%), Positives = 94/199 (47%), Gaps = 10/199 (5%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + G V+ Q + +A E +
Sbjct: 28 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 84
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGK-AGMISTGNLEDLNNVIDVNIYG 120
C + D + VKL+GG+D+LV+NAA+ G I E + +D+N+
Sbjct: 85 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 144
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
++ + M+ +G G +V V+SI + PS P + Y SK ++ TKTL EL
Sbjct: 145 PALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPS---PGFSPYNVSKTALLGLTKTLAIEL 200
Query: 181 KMINSKIKITSVSPGIVKT 199
N I++ ++PG++KT
Sbjct: 201 APRN--IRVNCLAPGLIKT 217
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 76.6 bits (180), Expect = 8e-14
Identities = 59/199 (29%), Positives = 94/199 (47%), Gaps = 10/199 (5%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + G V+ Q + +A E +
Sbjct: 28 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 84
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGK-AGMISTGNLEDLNNVIDVNIYG 120
C + D + VKL+GG+D+LV+NAA+ G I E + +D+N+
Sbjct: 85 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 144
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
++ + M+ +G G +V V+SI + PS P + Y SK ++ TKTL EL
Sbjct: 145 PALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPS---PGFSPYNVSKTALLGLTKTLAIEL 200
Query: 181 KMINSKIKITSVSPGIVKT 199
N I++ ++PG++KT
Sbjct: 201 APRN--IRVNCLAPGLIKT 217
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 76.6 bits (180), Expect = 8e-14
Identities = 59/199 (29%), Positives = 94/199 (47%), Gaps = 10/199 (5%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + G V+ Q + +A E +
Sbjct: 28 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 84
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGK-AGMISTGNLEDLNNVIDVNIYG 120
C + D + VKL+GG+D+LV+NAA+ G I E + +D+N+
Sbjct: 85 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 144
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
++ + M+ +G G +V V+SI + PS P + Y SK ++ TKTL EL
Sbjct: 145 PALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPS---PGFSPYNVSKTALLGLTKTLAIEL 200
Query: 181 KMINSKIKITSVSPGIVKT 199
N I++ ++PG++KT
Sbjct: 201 APRN--IRVNCLAPGLIKT 217
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 76.6 bits (180), Expect = 8e-14
Identities = 59/199 (29%), Positives = 94/199 (47%), Gaps = 10/199 (5%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + G V+ Q + +A E +
Sbjct: 10 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 66
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGK-AGMISTGNLEDLNNVIDVNIYG 120
C + D + VKL+GG+D+LV+NAA+ G I E + +D+N+
Sbjct: 67 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 126
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
++ + M+ +G G +V V+SI + PS P + Y SK ++ TKTL EL
Sbjct: 127 PALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPS---PGFSPYNVSKTALLGLTKTLAIEL 182
Query: 181 KMINSKIKITSVSPGIVKT 199
N I++ ++PG++KT
Sbjct: 183 APRN--IRVNCLAPGLIKT 199
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 75.8 bits (178), Expect = 1e-13
Identities = 59/199 (29%), Positives = 94/199 (47%), Gaps = 10/199 (5%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + G V+ Q + +A E +
Sbjct: 28 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 84
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGK-AGMISTGNLEDLNNVIDVNIYG 120
C + D + VKL+GG+D+LV+NAA+ G I E + +D+N+
Sbjct: 85 GTVCMVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 144
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
++ + M+ +G G +V V+SI + PS P + Y SK ++ TKTL EL
Sbjct: 145 PALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPS---PGFSPYNVSKTALLGLTKTLAIEL 200
Query: 181 KMINSKIKITSVSPGIVKT 199
N I++ ++PG++KT
Sbjct: 201 APRN--IRVNCLAPGLIKT 217
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 75.4 bits (177), Expect = 2e-13
Identities = 58/199 (29%), Positives = 94/199 (47%), Gaps = 10/199 (5%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + G V+ Q + +A E +
Sbjct: 10 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 66
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGK-AGMISTGNLEDLNNVIDVNIYG 120
C + D + VKL+GG+D+LV+NAA+ G + E + +D+N+
Sbjct: 67 GTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKA 126
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
++ + M+ +G G +V V+SI + PS P + Y SK ++ TKTL EL
Sbjct: 127 PALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPS---PGFSPYNVSKTALLGLTKTLAIEL 182
Query: 181 KMINSKIKITSVSPGIVKT 199
N I++ ++PG++KT
Sbjct: 183 APRN--IRVNCLAPGLIKT 199
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 74.9 bits (176), Expect = 2e-13
Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG Q T + K ++ ++ + + A + +L D SN
Sbjct: 40 LITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVE---ETAAECRKLGVTAHAYVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAA-IGKAGMISTGNLEDLNNVIDVNIYGLIACSRHA 128
++ + + K G V ++VNNA + A ++ST + E++ +VNI G ++
Sbjct: 97 REEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKD-EEITKTFEVNILGHFWITKAL 155
Query: 129 IDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI-NSKI 187
+ SM + GHIV V S+CGH P + Y +SK + F + L EL+ + + I
Sbjct: 156 LPSMMERNHGHIVTVASVCGHE----GIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 188 KITSVSPGIVKTGIFKS 204
K + + P V TG K+
Sbjct: 212 KTSCLCPVFVNTGFTKN 228
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 74.9 bits (176), Expect = 2e-13
Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG Q T + K ++ ++ + + A + +L D SN
Sbjct: 40 LITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVE---ETAAECRKLGVTAHAYVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAA-IGKAGMISTGNLEDLNNVIDVNIYGLIACSRHA 128
++ + + K G V ++VNNA + A ++ST + E++ +VNI G ++
Sbjct: 97 REEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKD-EEITKTFEVNILGHFWITKAL 155
Query: 129 IDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI-NSKI 187
+ SM + GHIV V S+CGH P + Y +SK + F + L EL+ + + I
Sbjct: 156 LPSMMERNHGHIVTVASVCGHE----GIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 188 KITSVSPGIVKTGIFKS 204
K + + P V TG K+
Sbjct: 212 KTSCLCPVFVNTGFTKN 228
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 74.9 bits (176), Expect = 2e-13
Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG Q T + K ++ ++ + + A + +L D SN
Sbjct: 40 LITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVE---ETAAECRKLGVTAHAYVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAA-IGKAGMISTGNLEDLNNVIDVNIYGLIACSRHA 128
++ + + K G V ++VNNA + A ++ST + E++ +VNI G ++
Sbjct: 97 REEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKD-EEITKTFEVNILGHFWITKAL 155
Query: 129 IDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI-NSKI 187
+ SM + GHIV V S+CGH P + Y +SK + F + L EL+ + + I
Sbjct: 156 LPSMMERNHGHIVTVASVCGHE----GIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 188 KITSVSPGIVKTGIFKS 204
K + + P V TG K+
Sbjct: 212 KTSCLCPVFVNTGFTKN 228
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 74.9 bits (176), Expect = 2e-13
Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG Q T + K ++ ++ + + A + +L D SN
Sbjct: 40 LITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVE---ETAAECRKLGVTAHAYVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAA-IGKAGMISTGNLEDLNNVIDVNIYGLIACSRHA 128
++ + + K G V ++VNNA + A ++ST + E++ +VNI G ++
Sbjct: 97 REEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKD-EEITKTFEVNILGHFWITKAL 155
Query: 129 IDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI-NSKI 187
+ SM + GHIV V S+CGH P + Y +SK + F + L EL+ + + I
Sbjct: 156 LPSMMERNHGHIVTVASVCGHE----GIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 188 KITSVSPGIVKTGIFKS 204
K + + P V TG K+
Sbjct: 212 KTSCLCPVFVNTGFTKN 228
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 74.9 bits (176), Expect = 2e-13
Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG Q T + K ++ ++ + + A + +L D SN
Sbjct: 40 LITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVE---ETAAECRKLGVTAHAYVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAA-IGKAGMISTGNLEDLNNVIDVNIYGLIACSRHA 128
++ + + K G V ++VNNA + A ++ST + E++ +VNI G ++
Sbjct: 97 REEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKD-EEITKTFEVNILGHFWITKAL 155
Query: 129 IDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI-NSKI 187
+ SM + GHIV V S+CGH P + Y +SK + F + L EL+ + + I
Sbjct: 156 LPSMMERNHGHIVTVASVCGHE----GIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 188 KITSVSPGIVKTGIFKS 204
K + + P V TG K+
Sbjct: 212 KTSCLCPVFVNTGFTKN 228
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 74.9 bits (176), Expect = 2e-13
Identities = 58/199 (29%), Positives = 93/199 (46%), Gaps = 10/199 (5%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+ T + GIG I L + G V+ Q + +A E +
Sbjct: 28 DPLANKVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 84
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGK-AGMISTGNLEDLNNVIDVNIYG 120
C + D + VKL+GG+D+LV+NAA+ G I E + +D+N+
Sbjct: 85 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKA 144
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
++ + M+ +G G +V V+SI + PS P + Y SK ++ TKTL EL
Sbjct: 145 PALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPS---PGFSPYNVSKTALLGLTKTLAIEL 200
Query: 181 KMINSKIKITSVSPGIVKT 199
N I++ ++PG++KT
Sbjct: 201 APRN--IRVNCLAPGLIKT 217
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 74.9 bits (176), Expect = 2e-13
Identities = 56/197 (28%), Positives = 95/197 (48%), Gaps = 10/197 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG Q T + K ++ ++ + + A + +L D SN
Sbjct: 40 LITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVE---ETAAECRKLGVTAHAYVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAA-IGKAGMISTGNLEDLNNVIDVNIYGLIACSRHA 128
++ + + K G V ++VNNA + A ++ST + E++ +VNI G ++
Sbjct: 97 REEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKD-EEITKTFEVNILGHFWITKAL 155
Query: 129 IDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI-NSKI 187
+ SM + GHIV V S+CGH P + Y +SK + F + L EL+ + + I
Sbjct: 156 LPSMMERNHGHIVTVASVCGHE----GIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 188 KITSVSPGIVKTGIFKS 204
K + + P V TG K+
Sbjct: 212 KTSCLCPVFVNTGFTKN 228
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 74.1 bits (174), Expect = 4e-13
Identities = 54/192 (28%), Positives = 92/192 (47%), Gaps = 16/192 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAG--MTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC 63
+K V G +GIG + + + + G + VI AK +L +
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAA--------GDLGGDHLAF 53
Query: 64 KCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIA 123
CD++ ++D++N FE + K G V+ LVN A I + G++ ED+ + + N+ G +
Sbjct: 54 SCDVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSML 113
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ A+ +M + G IVNV SI G +VY ASK + F++ L +E +
Sbjct: 114 TCKAAMRTMIQQQGGSIVNVGSIVG----LKGNSGQSVYSASKGGLVGFSRALAKE--VA 167
Query: 184 NSKIKITSVSPG 195
KI++ V+PG
Sbjct: 168 RKKIRVNVVAPG 179
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/199 (25%), Positives = 100/199 (50%), Gaps = 6/199 (3%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQ-LIPCKCDISN 69
VTGA GIG ++ L K G++++ +L + + L + ++ D+++
Sbjct: 55 VTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTD 114
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ A + +++ +G +D+LVNN + + + +L+ +I++N G ++ ++ +
Sbjct: 115 TGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVL 174
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M + +G IV VNSI G S P+ Y ASK ++ F LR EL I +
Sbjct: 175 PHMIERKQGKIVTVNSILG----IISVPLSIGYCASKHALRGFFNGLRTELATYPG-IIV 229
Query: 190 TSVSPGIVKTGIFKSAGVG 208
+++ PG V++ I +++ G
Sbjct: 230 SNICPGPVQSNIVENSLAG 248
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/199 (25%), Positives = 100/199 (50%), Gaps = 6/199 (3%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQ-LIPCKCDISN 69
VTGA GIG ++ L K G++++ +L + + L + ++ D+++
Sbjct: 55 VTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTD 114
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ A + +++ +G +D+LVNN + + + +L+ +I++N G ++ ++ +
Sbjct: 115 TGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVL 174
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M + +G IV VNSI G S P+ Y ASK ++ F LR EL I +
Sbjct: 175 PHMIERKQGKIVTVNSILG----IISVPLSIGYCASKHALRGFFNGLRTELATYPG-IIV 229
Query: 190 TSVSPGIVKTGIFKSAGVG 208
+++ PG V++ I +++ G
Sbjct: 230 SNICPGPVQSNIVENSLAG 248
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/199 (25%), Positives = 100/199 (50%), Gaps = 6/199 (3%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQ-LIPCKCDISN 69
VTGA GIG ++ L K G++++ +L + + L + ++ D+++
Sbjct: 5 VTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTD 64
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ A + +++ +G +D+LVNN + + + +L+ +I++N G ++ ++ +
Sbjct: 65 TGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVL 124
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M + +G IV VNSI G S P+ Y ASK ++ F LR EL I +
Sbjct: 125 PHMIERKQGKIVTVNSILG----IISVPLSIGYCASKHALRGFFNGLRTELATYPG-IIV 179
Query: 190 TSVSPGIVKTGIFKSAGVG 208
+++ PG V++ I +++ G
Sbjct: 180 SNICPGPVQSNIVENSLAG 198
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/199 (25%), Positives = 100/199 (50%), Gaps = 6/199 (3%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQ-LIPCKCDISN 69
VTGA GIG ++ L K G++++ +L + + L + ++ D+++
Sbjct: 55 VTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTD 114
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ A + +++ +G +D+LVNN + + + +L+ +I++N G ++ ++ +
Sbjct: 115 TGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVL 174
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M + +G IV VNSI G S P+ Y ASK ++ F LR EL I +
Sbjct: 175 PHMIERKQGKIVTVNSILG----IISVPLSIGYCASKHALRGFFNGLRTELATYPG-IIV 229
Query: 190 TSVSPGIVKTGIFKSAGVG 208
+++ PG V++ I +++ G
Sbjct: 230 SNICPGPVQSNIVENSLAG 248
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/199 (25%), Positives = 100/199 (50%), Gaps = 6/199 (3%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQ-LIPCKCDISN 69
VTGA GIG ++ L K G++++ +L + + L + ++ D+++
Sbjct: 5 VTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTD 64
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ A + +++ +G +D+LVNN + + + +L+ +I++N G ++ ++ +
Sbjct: 65 TGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVL 124
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M + +G IV VNSI G S P+ Y ASK ++ F LR EL I +
Sbjct: 125 PHMIERKQGKIVTVNSILG----IISVPLSIGYCASKHALRGFFNGLRTELATYPG-IIV 179
Query: 190 TSVSPGIVKTGIFKSAGVG 208
+++ PG V++ I +++ G
Sbjct: 180 SNICPGPVQSNIVENSLAG 198
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 70.5 bits (165), Expect = 5e-12
Identities = 52/199 (26%), Positives = 87/199 (43%), Gaps = 8/199 (4%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ ++TGAG GIG + K ++ ++ + L A K L ++ D
Sbjct: 37 ETVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVD 93
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
SN D+ ++ + + G V +LVNNA + + + +VN+ ++
Sbjct: 94 CSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTK 153
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-S 185
+ +M GHIV V S GH S P + Y +SK + F KTL +EL + +
Sbjct: 154 AFLPAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQIT 209
Query: 186 KIKITSVSPGIVKTGIFKS 204
+K T + P V TG K+
Sbjct: 210 GVKTTCLCPNFVNTGFIKN 228
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 70.1 bits (164), Expect = 7e-12
Identities = 52/196 (26%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG + K ++ ++ + L A K L ++ D SN
Sbjct: 40 LITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
D+ ++ + + G V +LVNNA + + + +VN+ ++ +
Sbjct: 97 REDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-SKIK 188
+M GHIV V S GH S P + Y +SK + F KTL +EL + + +K
Sbjct: 157 PAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVK 212
Query: 189 ITSVSPGIVKTGIFKS 204
T + P V TG K+
Sbjct: 213 TTCLCPNFVNTGFIKN 228
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 70.1 bits (164), Expect = 7e-12
Identities = 52/196 (26%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG + K ++ ++ + L A K L ++ D SN
Sbjct: 40 LITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
D+ ++ + + G V +LVNNA + + + +VN+ ++ +
Sbjct: 97 REDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-SKIK 188
+M GHIV V S GH S P + Y +SK + F KTL +EL + + +K
Sbjct: 157 PAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVK 212
Query: 189 ITSVSPGIVKTGIFKS 204
T + P V TG K+
Sbjct: 213 TTCLCPNFVNTGFIKN 228
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 70.1 bits (164), Expect = 7e-12
Identities = 52/196 (26%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG + K ++ ++ + L A K L ++ D SN
Sbjct: 40 LITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
D+ ++ + + G V +LVNNA + + + +VN+ ++ +
Sbjct: 97 REDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-SKIK 188
+M GHIV V S GH S P + Y +SK + F KTL +EL + + +K
Sbjct: 157 PAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVK 212
Query: 189 ITSVSPGIVKTGIFKS 204
T + P V TG K+
Sbjct: 213 TTCLCPNFVNTGFIKN 228
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 70.1 bits (164), Expect = 7e-12
Identities = 52/196 (26%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG + K ++ ++ + L A K L ++ D SN
Sbjct: 40 LITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
D+ ++ + + G V +LVNNA + + + +VN+ ++ +
Sbjct: 97 REDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-SKIK 188
+M GHIV V S GH S P + Y +SK + F KTL +EL + + +K
Sbjct: 157 PAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVK 212
Query: 189 ITSVSPGIVKTGIFKS 204
T + P V TG K+
Sbjct: 213 TTCLCPNFVNTGFIKN 228
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 70.1 bits (164), Expect = 7e-12
Identities = 52/196 (26%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG + K ++ ++ + L A K L ++ D SN
Sbjct: 40 LITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
D+ ++ + + G V +LVNNA + + + +VN+ ++ +
Sbjct: 97 REDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-SKIK 188
+M GHIV V S GH S P + Y +SK + F KTL +EL + + +K
Sbjct: 157 PAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVK 212
Query: 189 ITSVSPGIVKTGIFKS 204
T + P V TG K+
Sbjct: 213 TTCLCPNFVNTGFIKN 228
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 70.1 bits (164), Expect = 7e-12
Identities = 52/196 (26%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG + K ++ ++ + L A K L ++ D SN
Sbjct: 40 LITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
D+ ++ + + G V +LVNNA + + + +VN+ ++ +
Sbjct: 97 REDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-SKIK 188
+M GHIV V S GH S P + Y +SK + F KTL +EL + + +K
Sbjct: 157 PAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVK 212
Query: 189 ITSVSPGIVKTGIFKS 204
T + P V TG K+
Sbjct: 213 TTCLCPNFVNTGFIKN 228
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 70.1 bits (164), Expect = 7e-12
Identities = 55/194 (28%), Positives = 87/194 (44%), Gaps = 10/194 (5%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSE-LNNQLIPCKC 65
+ +++G GIG ++ L T L L E L L +
Sbjct: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQL 65
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+ +D + I G VD+LVNNA +G G + +L + NV D N +G +
Sbjct: 66 DVCSDESVAQCLSCI---QGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLV 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ + MK + +GHIV ++S+ G F++ VY ASK ++ F ++L +L N
Sbjct: 123 KAVLPGMKRRRQGHIVVISSVMGLQGVIFND----VYAASKFALEGFFESLAIQLLQFN- 177
Query: 186 KIKITSVSPGIVKT 199
I I+ V PG V T
Sbjct: 178 -IFISLVEPGPVVT 190
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 70.1 bits (164), Expect = 7e-12
Identities = 52/196 (26%), Positives = 86/196 (43%), Gaps = 8/196 (4%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG + K ++ ++ + L A K L ++ D SN
Sbjct: 40 LITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
D+ ++ + + G V +LVNNA + + + +VN+ ++ +
Sbjct: 97 REDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-SKIK 188
+M GHIV V S GH S P + Y +SK + F KTL +EL + + +K
Sbjct: 157 PAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVK 212
Query: 189 ITSVSPGIVKTGIFKS 204
T + P V TG K+
Sbjct: 213 TTCLCPNFVNTGFIKN 228
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 69.7 bits (163), Expect = 9e-12
Identities = 52/176 (29%), Positives = 86/176 (48%), Gaps = 16/176 (9%)
Query: 3 HWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIP 62
H K A+VTGA QGIG E L+ G V + D+ E L
Sbjct: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF- 60
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLI 122
+CD+++ L++ F +V +G +D+LVNNA + N ++ + +N+ +I
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNKKNWEKTLQINLVSVI 112
Query: 123 ACSRHAID--SMKNKGKGH-IVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKT 175
+ + +D S +N G+G I+N++S+ G MP +P VY ASK + FT++
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAG-LMPVAQQP---VYCASKHGIVGFTRS 164
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 69.7 bits (163), Expect = 9e-12
Identities = 46/176 (26%), Positives = 83/176 (47%), Gaps = 8/176 (4%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVI----GFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+TGA +GIG I K G ++ +P L ++ A++ + + +PC D
Sbjct: 15 ITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVD 74
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNA-AIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
+ ++ + A E +K +GG+D+LVNNA AI + T + L+ +++VN G S
Sbjct: 75 VRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPT-KRLDLMMNVNTRGTYLAS 133
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ I +K HI+N++ F + Y +K M+++ + EE K
Sbjct: 134 KACIPYLKKSKVAHILNISPPLNLNPVWFKQHC--AYTIAKYGMSMYVLGMAEEFK 187
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 69.7 bits (163), Expect = 9e-12
Identities = 46/176 (26%), Positives = 83/176 (47%), Gaps = 8/176 (4%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVI----GFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+TGA +GIG I K G ++ +P L ++ A++ + + +PC D
Sbjct: 15 ITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVD 74
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNA-AIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
+ ++ + A E +K +GG+D+LVNNA AI + T + L+ +++VN G S
Sbjct: 75 VRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPT-KRLDLMMNVNTRGTYLAS 133
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ I +K HI+N++ F + Y +K M+++ + EE K
Sbjct: 134 KACIPYLKKSKVAHILNISPPLNLNPVWFKQHC--AYTIAKYGMSMYVLGMAEEFK 187
>AL162732-2|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 69.7 bits (163), Expect = 9e-12
Identities = 46/176 (26%), Positives = 83/176 (47%), Gaps = 8/176 (4%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVI----GFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+TGA +GIG I K G ++ +P L ++ A++ + + +PC D
Sbjct: 15 ITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVD 74
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNA-AIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
+ ++ + A E +K +GG+D+LVNNA AI + T + L+ +++VN G S
Sbjct: 75 VRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPT-KRLDLMMNVNTRGTYLAS 133
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ I +K HI+N++ F + Y +K M+++ + EE K
Sbjct: 134 KACIPYLKKSKVAHILNISPPLNLNPVWFKQHC--AYTIAKYGMSMYVLGMAEEFK 187
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 68.9 bits (161), Expect = 2e-11
Identities = 52/195 (26%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG GIG + K ++ ++ + L A K L ++ D SN
Sbjct: 40 LITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLE---ETAAKCKGLGAKVHTFVVDCSN 96
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
D+ ++ + G V +LVNNA + + + +VN+ ++ +
Sbjct: 97 REDIYSSAKNCKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFL 156
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN-SKIK 188
+M GHIV V S GH S P + Y +SK + F KTL +EL + + +K
Sbjct: 157 PAMTKNNHGHIVTVASAAGH----VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVK 212
Query: 189 ITSVSPGIVKTGIFK 203
T + P V TG K
Sbjct: 213 TTCLCPNFVNTGFIK 227
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 68.5 bits (160), Expect = 2e-11
Identities = 64/208 (30%), Positives = 97/208 (46%), Gaps = 24/208 (11%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+A +VTGA +GIG I L KAG TV T L L +A + L Q +P CD
Sbjct: 8 QACVVTGASRGIGRGIALQLCKAGATVY---ITGRHLDTLRVVAQEAQSLGGQCVPVVCD 64
Query: 67 ISNDNDLKNAFEGIVK-LYGGVDLLVNNAAIGKAGMISTGN----------LEDLNNVID 115
S ++++++ FE + + G +D+LVNNA G +++T N +D+NN
Sbjct: 65 SSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINN--- 121
Query: 116 VNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKT 175
V + G CS + M G+G IV ++S G F+ P Y K +
Sbjct: 122 VGLRGHYFCSVYGARLMVPAGQGLIVVISS-PGSLQYMFNVP----YGVGKAACDKLAAD 176
Query: 176 LREELKMINSKIKITSVSPGIVKTGIFK 203
EL+ + S+ PGIV+T + K
Sbjct: 177 CAHELR--RHGVSCVSLWPGIVQTELLK 202
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 66.9 bits (156), Expect = 6e-11
Identities = 63/209 (30%), Positives = 97/209 (46%), Gaps = 26/209 (12%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGA +GIG I L KAG TV T L L +A + L Q +P CD
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVY---ITGRHLDTLRVVAQEAQSLGGQCVPVVCD 64
Query: 67 ISNDNDLKNAFEGIVK-LYGGVDLLVNNAAIGKAGMISTGN----------LEDLNNVID 115
S ++++++ FE + + G +D+LVNNA G +++T N +D+NN
Sbjct: 65 SSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINN--- 121
Query: 116 VNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNV-YIASKRSMTVFTK 174
V + G CS + M G+G IV ++S P + + NV Y K +
Sbjct: 122 VGLRGHYFCSVYGARLMVPAGQGLIVVISS------PGSLQYMFNVLYGVGKAACDKLAA 175
Query: 175 TLREELKMINSKIKITSVSPGIVKTGIFK 203
EL+ + S+ PGIV+T + K
Sbjct: 176 DCAHELR--RHGVSCVSLWPGIVQTELLK 202
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 66.9 bits (156), Expect = 6e-11
Identities = 63/208 (30%), Positives = 96/208 (46%), Gaps = 24/208 (11%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGA +GIG I L KAG TV T L L +A + L Q +P CD
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVY---ITGRHLDTLRVVAQEAQSLGGQCVPVVCD 64
Query: 67 ISNDNDLKNAFEGIVK-LYGGVDLLVNNAAIGKAGMISTGN----------LEDLNNVID 115
S ++++++ FE + + G +D+LVNNA G +++T N +D+NN
Sbjct: 65 SSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINN--- 121
Query: 116 VNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKT 175
V + G CS + M G+G IV ++S G F+ P Y K +
Sbjct: 122 VGLRGHYFCSVYGARLMVPAGQGLIVVISS-PGSLQYMFNVP----YGVGKAACDKLAAD 176
Query: 176 LREELKMINSKIKITSVSPGIVKTGIFK 203
EL+ + S+ PGIV+T + K
Sbjct: 177 CAHELR--RHGVSCVSLWPGIVQTELLK 202
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 66.9 bits (156), Expect = 6e-11
Identities = 63/208 (30%), Positives = 96/208 (46%), Gaps = 24/208 (11%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGA +GIG I L KAG TV T L L +A + L Q +P CD
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVY---ITGRHLDTLRVVAQEAQSLGGQCVPVVCD 64
Query: 67 ISNDNDLKNAFEGIVK-LYGGVDLLVNNAAIGKAGMISTGN----------LEDLNNVID 115
S ++++++ FE + + G +D+LVNNA G +++T N +D+NN
Sbjct: 65 SSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINN--- 121
Query: 116 VNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKT 175
V + G CS + M G+G IV ++S G F+ P Y K +
Sbjct: 122 VGLRGHYFCSVYGARLMVPAGQGLIVVISS-PGSLQYMFNVP----YGVGKAACDKLAAD 176
Query: 176 LREELKMINSKIKITSVSPGIVKTGIFK 203
EL+ + S+ PGIV+T + K
Sbjct: 177 CAHELR--RHGVSCVSLWPGIVQTELLK 202
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/201 (22%), Positives = 99/201 (49%), Gaps = 15/201 (7%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC 63
+ K +VTG G+GIGA I + +G V+ + ++ L EL +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL------EQELPGAVF-I 59
Query: 64 KCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGM-ISTGNLEDLNNVIDVNIYGLI 122
CD++ ++D+K ++ +G +D +VNNA + + ++++N+ G
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
++ A+ ++ K +G+++N++S+ G + + P Y+A+K ++T TK L L
Sbjct: 120 TLTKLALPYLR-KSQGNVINISSLVGAIGQAQAVP----YVATKGAVTAMTKAL--ALDE 172
Query: 183 INSKIKITSVSPGIVKTGIFK 203
+++ +SPG + T +++
Sbjct: 173 SPYGVRVNCISPGNIWTPLWE 193
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/201 (22%), Positives = 99/201 (49%), Gaps = 15/201 (7%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC 63
+ K +VTG G+GIGA I + +G V+ + ++ L EL +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL------EQELPGAVF-I 59
Query: 64 KCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGM-ISTGNLEDLNNVIDVNIYGLI 122
CD++ ++D+K ++ +G +D +VNNA + + ++++N+ G
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
++ A+ ++ K +G+++N++S+ G + + P Y+A+K ++T TK L L
Sbjct: 120 TLTKLALPYLR-KSQGNVINISSLVGAIGQAQAVP----YVATKGAVTAMTKAL--ALDE 172
Query: 183 INSKIKITSVSPGIVKTGIFK 203
+++ +SPG + T +++
Sbjct: 173 SPYGVRVNCISPGNIWTPLWE 193
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/201 (22%), Positives = 99/201 (49%), Gaps = 15/201 (7%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC 63
+ K +VTG G+GIGA I + +G V+ + ++ L EL +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL------EQELPGAVF-I 59
Query: 64 KCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGM-ISTGNLEDLNNVIDVNIYGLI 122
CD++ ++D+K ++ +G +D +VNNA + + ++++N+ G
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
++ A+ ++ K +G+++N++S+ G + + P Y+A+K ++T TK L L
Sbjct: 120 TLTKLALPYLR-KSQGNVINISSLVGAIGQAQAVP----YVATKGAVTAMTKAL--ALDE 172
Query: 183 INSKIKITSVSPGIVKTGIFK 203
+++ +SPG + T +++
Sbjct: 173 SPYGVRVNCISPGNIWTPLWE 193
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/201 (22%), Positives = 99/201 (49%), Gaps = 15/201 (7%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC 63
+ K +VTG G+GIGA I + +G V+ + ++ L EL +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRAL------EQELPGAVF-I 59
Query: 64 KCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGM-ISTGNLEDLNNVIDVNIYGLI 122
CD++ ++D+K ++ +G +D +VNNA + + ++++N+ G
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
++ A+ ++ K +G+++N++S+ G + + P Y+A+K ++T TK L L
Sbjct: 120 TLTKLALPYLR-KSQGNVINISSLVGAIGQAQAVP----YVATKGAVTAMTKAL--ALDE 172
Query: 183 INSKIKITSVSPGIVKTGIFK 203
+++ +SPG + T +++
Sbjct: 173 SPYGVRVNCISPGNIWTPLWE 193
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 64.5 bits (150), Expect = 3e-10
Identities = 52/198 (26%), Positives = 104/198 (52%), Gaps = 14/198 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDIS 68
A++TGAG GIG + +L K G+ V+ T KL + ++ + + ++I + D +
Sbjct: 51 AVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKII--QADFT 108
Query: 69 NDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGLIACS 125
D+ ++ E + L G+ LVNN + ++ + L +++ ++I NI ++ +
Sbjct: 109 KDDIYEHIKEKLAGLEIGI--LVNNVGM-LPNLLPSHFLNAPDEIQSLIHCNITSVVKMT 165
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ + M+++ KG I+N++S + F P+ ++Y ASK + F+K L+EE K
Sbjct: 166 QLILKHMESRQKGLILNISS----GIALFPWPLYSMYSASKAFVCAFSKALQEEYKA--K 219
Query: 186 KIKITSVSPGIVKTGIFK 203
++ I ++P V T + K
Sbjct: 220 EVIIQVLTPYAVSTAMTK 237
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 64.5 bits (150), Expect = 3e-10
Identities = 52/198 (26%), Positives = 104/198 (52%), Gaps = 14/198 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDIS 68
A++TGAG GIG + +L K G+ V+ T KL + ++ + + ++I + D +
Sbjct: 51 AVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKII--QADFT 108
Query: 69 NDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGLIACS 125
D+ ++ E + L G+ LVNN + ++ + L +++ ++I NI ++ +
Sbjct: 109 KDDIYEHIKEKLAGLEIGI--LVNNVGM-LPNLLPSHFLNAPDEIQSLIHCNITSVVKMT 165
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ + M+++ KG I+N++S + F P+ ++Y ASK + F+K L+EE K
Sbjct: 166 QLILKHMESRQKGLILNISS----GIALFPWPLYSMYSASKAFVCAFSKALQEEYKA--K 219
Query: 186 KIKITSVSPGIVKTGIFK 203
++ I ++P V T + K
Sbjct: 220 EVIIQVLTPYAVSTAMTK 237
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 64.5 bits (150), Expect = 3e-10
Identities = 52/198 (26%), Positives = 104/198 (52%), Gaps = 14/198 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDIS 68
A++TGAG GIG + +L K G+ V+ T KL + ++ + + ++I + D +
Sbjct: 51 AVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKII--QADFT 108
Query: 69 NDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGLIACS 125
D+ ++ E + L G+ LVNN + ++ + L +++ ++I NI ++ +
Sbjct: 109 KDDIYEHIKEKLAGLEIGI--LVNNVGM-LPNLLPSHFLNAPDEIQSLIHCNITSVVKMT 165
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ + M+++ KG I+N++S + F P+ ++Y ASK + F+K L+EE K
Sbjct: 166 QLILKHMESRQKGLILNISS----GIALFPWPLYSMYSASKAFVCAFSKALQEEYKA--K 219
Query: 186 KIKITSVSPGIVKTGIFK 203
++ I ++P V T + K
Sbjct: 220 EVIIQVLTPYAVSTAMTK 237
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 64.5 bits (150), Expect = 3e-10
Identities = 52/198 (26%), Positives = 104/198 (52%), Gaps = 14/198 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDIS 68
A++TGAG GIG + +L K G+ V+ T KL + ++ + + ++I + D +
Sbjct: 51 AVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKII--QADFT 108
Query: 69 NDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGLIACS 125
D+ ++ E + L G+ LVNN + ++ + L +++ ++I NI ++ +
Sbjct: 109 KDDIYEHIKEKLAGLEIGI--LVNNVGM-LPNLLPSHFLNAPDEIQSLIHCNITSVVKMT 165
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ + M+++ KG I+N++S + F P+ ++Y ASK + F+K L+EE K
Sbjct: 166 QLILKHMESRQKGLILNISS----GIALFPWPLYSMYSASKAFVCAFSKALQEEYKA--K 219
Query: 186 KIKITSVSPGIVKTGIFK 203
++ I ++P V T + K
Sbjct: 220 EVIIQVLTPYAVSTAMTK 237
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 64.5 bits (150), Expect = 3e-10
Identities = 52/198 (26%), Positives = 104/198 (52%), Gaps = 14/198 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDIS 68
A++TGAG GIG + +L K G+ V+ T KL + ++ + + ++I + D +
Sbjct: 51 AVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKII--QADFT 108
Query: 69 NDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGLIACS 125
D+ ++ E + L G+ LVNN + ++ + L +++ ++I NI ++ +
Sbjct: 109 KDDIYEHIKEKLAGLEIGI--LVNNVGM-LPNLLPSHFLNAPDEIQSLIHCNITSVVKMT 165
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ + M+++ KG I+N++S + F P+ ++Y ASK + F+K L+EE K
Sbjct: 166 QLILKHMESRQKGLILNISS----GIALFPWPLYSMYSASKAFVCAFSKALQEEYKA--K 219
Query: 186 KIKITSVSPGIVKTGIFK 203
++ I ++P V T + K
Sbjct: 220 EVIIQVLTPYAVSTAMTK 237
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 63.3 bits (147), Expect = 8e-10
Identities = 50/182 (27%), Positives = 82/182 (45%), Gaps = 6/182 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC-KCDIS 68
+VTG GIG I + K G + + KL + +S + Q++ C D+S
Sbjct: 36 VVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVS 95
Query: 69 ND-NDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRH 127
D N ++N + + G VD+LVN A + +G + ++ +N G + SR
Sbjct: 96 QDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRA 155
Query: 128 AIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKI 187
I +MK + G IV V+S G + F Y ASK ++ + L+ E+K N I
Sbjct: 156 VITTMKERRVGRIVFVSSQAGQ-LGLFG---FTAYSASKFAIRGLAEALQMEVKPYNVYI 211
Query: 188 KI 189
+
Sbjct: 212 TV 213
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 63.3 bits (147), Expect = 8e-10
Identities = 50/182 (27%), Positives = 82/182 (45%), Gaps = 6/182 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC-KCDIS 68
+VTG GIG I + K G + + KL + +S + Q++ C D+S
Sbjct: 36 VVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVS 95
Query: 69 ND-NDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRH 127
D N ++N + + G VD+LVN A + +G + ++ +N G + SR
Sbjct: 96 QDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRA 155
Query: 128 AIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKI 187
I +MK + G IV V+S G + F Y ASK ++ + L+ E+K N I
Sbjct: 156 VITTMKERRVGRIVFVSSQAGQ-LGLFG---FTAYSASKFAIRGLAEALQMEVKPYNVYI 211
Query: 188 KI 189
+
Sbjct: 212 TV 213
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 63.3 bits (147), Expect = 8e-10
Identities = 50/182 (27%), Positives = 82/182 (45%), Gaps = 6/182 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPC-KCDIS 68
+VTG GIG I + K G + + KL + +S + Q++ C D+S
Sbjct: 36 VVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVS 95
Query: 69 ND-NDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRH 127
D N ++N + + G VD+LVN A + +G + ++ +N G + SR
Sbjct: 96 QDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRA 155
Query: 128 AIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKI 187
I +MK + G IV V+S G + F Y ASK ++ + L+ E+K N I
Sbjct: 156 VITTMKERRVGRIVFVSSQAGQ-LGLFG---FTAYSASKFAIRGLAEALQMEVKPYNVYI 211
Query: 188 KI 189
+
Sbjct: 212 TV 213
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 62.5 bits (145), Expect = 1e-09
Identities = 54/206 (26%), Positives = 93/206 (45%), Gaps = 11/206 (5%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
N+ A+VTG+ GIG I L + G V+ Q + +A E + C
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRA--MAKLQGE-GLSVAGIVC 92
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDL-NNVIDVNIYGLIAC 124
+ D + ++ GGVD LV +A + + G E + + ++ VN+
Sbjct: 93 HVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALL 152
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
+ M+N+ +G ++ V+SI Y P + + VY SK ++ T+TL L++
Sbjct: 153 LSQLLPYMENR-RGAVILVSSIAA-YNPVVA---LGVYNVSKTALLGLTRTLA--LELAP 205
Query: 185 SKIKITSVSPGIVKTGIFKSAGVGFI 210
I++ V PGI+KT K +GF+
Sbjct: 206 KDIRVNCVVPGIIKTDFSKVVRIGFM 231
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/176 (26%), Positives = 94/176 (53%), Gaps = 12/176 (6%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDIS 68
A++TGAG GIG + +L K G+ V+ T KL + ++ + + ++I + D +
Sbjct: 51 AVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKII--QADFT 108
Query: 69 NDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGLIACS 125
D+ ++ E + L G+ LVNN + ++ + L +++ ++I NI ++ +
Sbjct: 109 KDDIYEHIKEKLAGLEIGI--LVNNVGM-LPNLLPSHFLNAPDEIQSLIHCNITSVVKMT 165
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ + M+++ KG I+N++S + F P+ ++Y ASK + F+K L+EE K
Sbjct: 166 QLILKHMESRQKGLILNISS----GIALFPWPLYSMYSASKAFVCAFSKALQEEYK 217
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 60.9 bits (141), Expect = 4e-09
Identities = 42/151 (27%), Positives = 73/151 (48%), Gaps = 12/151 (7%)
Query: 3 HWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIP 62
H K A+VTGA QGIG E L+ G V + D+ E L
Sbjct: 2 HVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF- 60
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLI 122
+CD+++ L++ F +V +G +D+LVNNA + N ++ + +N+ +I
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVI 112
Query: 123 ACSRHAID--SMKNKGKGH-IVNVNSICGHY 150
+ + +D S +N G+G I+N++S+ H+
Sbjct: 113 SGTYLGLDYMSKQNGGEGGIIINMSSLAAHH 143
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 60.9 bits (141), Expect = 4e-09
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 14/199 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDIS 68
A+VTG+ GIG E+L K GM V+ ++ KL + + + ++ + I D +
Sbjct: 53 AVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTI--AVDFA 110
Query: 69 NDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNV----IDVNIYGLIAC 124
+++ G+ L G+ LVNN + ++ DL+NV I++NI +
Sbjct: 111 SEDIYDKIKTGLAGLEIGI--LVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKM 168
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
++ + M + KG I+N++S G +P P++ +Y A+K + F++ L EE + +
Sbjct: 169 TQLVLPGMVERSKGAILNISSGSG-MLP---VPLLTIYSATKTFVDFFSQCLHEEYR--S 222
Query: 185 SKIKITSVSPGIVKTGIFK 203
+ + SV P V T + K
Sbjct: 223 KGVFVQSVLPYFVATKLAK 241
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 60.9 bits (141), Expect = 4e-09
Identities = 53/199 (26%), Positives = 98/199 (49%), Gaps = 14/199 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDIS 68
A+VTG+ GIG E+L K GM V+ ++ KL + + + ++ + I D +
Sbjct: 53 AVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTI--AVDFA 110
Query: 69 NDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNV----IDVNIYGLIAC 124
+++ G+ L G+ LVNN + ++ DL+NV I++NI +
Sbjct: 111 SEDIYDKIKTGLAGLEIGI--LVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKM 168
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
++ + M + KG I+N++S G +P P++ +Y A+K + F++ L EE + +
Sbjct: 169 TQLVLPGMVERSKGAILNISSGSG-MLP---VPLLTIYSATKTFVDFFSQCLHEEYR--S 222
Query: 185 SKIKITSVSPGIVKTGIFK 203
+ + SV P V T + K
Sbjct: 223 KGVFVQSVLPYFVATKLAK 241
>AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid
dehydrogenase isoform 1 protein.
Length = 264
Score = 60.5 bits (140), Expect = 6e-09
Identities = 41/127 (32%), Positives = 66/127 (51%), Gaps = 7/127 (5%)
Query: 80 IVKLYGGVDLLVNNAA-IGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMKNKGKG 138
+ K G V ++VNNA + A ++ST + E++ +VNI G ++ + SM + G
Sbjct: 71 VKKEVGDVTIVVNNAGTVYPADLLSTKD-EEITKTFEVNILGHFWITKALLPSMMERNHG 129
Query: 139 HIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI-NSKIKITSVSPGIV 197
HIV V S+CGH P + Y +SK + F + L EL+ + + IK + + P V
Sbjct: 130 HIVTVASVCGHE----GIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFV 185
Query: 198 KTGIFKS 204
TG K+
Sbjct: 186 NTGFTKN 192
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 60.5 bits (140), Expect = 6e-09
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 60
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 116
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
A + +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 117 IAARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 170
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 171 KIRVNAVNPTVVMTSM 186
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 60.1 bits (139), Expect = 7e-09
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 17/199 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKM 182
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMKA 196
Query: 183 INSKIKITSVSPGIVKTGI 201
+ ++ + PG+ KT +
Sbjct: 197 FG--VHVSCIEPGLFKTNL 213
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 59.3 bits (137), Expect = 1e-08
Identities = 59/242 (24%), Positives = 112/242 (46%), Gaps = 21/242 (8%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSE-----LNNQ 59
+ + AIVTG GIG I ++L++ G V+ KL L + AD+ +
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVV---IASRKLERLKSAADELQANLPPTKQAR 73
Query: 60 LIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+IP +C+I N+ ++ N + + +G ++ LVNN + + + V++ N+
Sbjct: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133
Query: 120 GLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREE 179
G + S + G IVN+ +P+ + + V+ + R+ V+ T
Sbjct: 134 GTFYMCKAVYSSWMKEHGGSIVNI------IVPTKAGFPLAVHSGAARA-GVYNLTKSLA 186
Query: 180 LKMINSKIKITSVSPGIV--KTGI--FKSAGVGFIDDAF-FCDNSHLTV-KDVSEVILMI 233
L+ S I+I V+PG++ +T + + S G F + +F + V ++VS V+ +
Sbjct: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246
Query: 234 LS 235
LS
Sbjct: 247 LS 248
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 59.3 bits (137), Expect = 1e-08
Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 8/187 (4%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + V+ Q + +A E +
Sbjct: 26 DPLTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 82
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGK-AGMISTGNLEDLNNVIDVNIYG 120
C + D + VKL+GG+D+LV+NAA+ G + E + +D+N+
Sbjct: 83 GTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKA 142
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
++ + M+ +G G +V V+SI + PS P + Y SK ++ TL EL
Sbjct: 143 PALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPS---PGFSPYNVSKTALLGLNNTLAIEL 198
Query: 181 KMINSKI 187
N ++
Sbjct: 199 APRNIRV 205
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 59.3 bits (137), Expect = 1e-08
Identities = 59/242 (24%), Positives = 112/242 (46%), Gaps = 21/242 (8%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSE-----LNNQ 59
+ + AIVTG GIG I ++L++ G V+ KL L + AD+ +
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVV---IASRKLERLKSAADELQANLPPTKQAR 73
Query: 60 LIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+IP +C+I N+ ++ N + + +G ++ LVNN + + + V++ N+
Sbjct: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133
Query: 120 GLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREE 179
G + S + G IVN+ +P+ + + V+ + R+ V+ T
Sbjct: 134 GTFYMCKAVYSSWMKEHGGSIVNI------IVPTKAGFPLAVHSGAARA-GVYNLTKSLA 186
Query: 180 LKMINSKIKITSVSPGIV--KTGI--FKSAGVGFIDDAF-FCDNSHLTV-KDVSEVILMI 233
L+ S I+I V+PG++ +T + + S G F + +F + V ++VS V+ +
Sbjct: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246
Query: 234 LS 235
LS
Sbjct: 247 LS 248
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 59.3 bits (137), Expect = 1e-08
Identities = 59/242 (24%), Positives = 112/242 (46%), Gaps = 21/242 (8%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSE-----LNNQ 59
+ + AIVTG GIG I ++L++ G V+ KL L + AD+ +
Sbjct: 36 QGQVAIVTGGATGIGKAIVKELLELGSNVV---IASRKLERLKSAADELQANLPPTKQAR 92
Query: 60 LIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+IP +C+I N+ ++ N + + +G ++ LVNN + + + V++ N+
Sbjct: 93 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 152
Query: 120 GLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREE 179
G + S + G IVN+ +P+ + + V+ + R+ V+ T
Sbjct: 153 GTFYMCKAVYSSWMKEHGGSIVNI------IVPTKAGFPLAVHSGAARA-GVYNLTKSLA 205
Query: 180 LKMINSKIKITSVSPGIV--KTGI--FKSAGVGFIDDAF-FCDNSHLTV-KDVSEVILMI 233
L+ S I+I V+PG++ +T + + S G F + +F + V ++VS V+ +
Sbjct: 206 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 265
Query: 234 LS 235
LS
Sbjct: 266 LS 267
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 59.3 bits (137), Expect = 1e-08
Identities = 59/242 (24%), Positives = 112/242 (46%), Gaps = 21/242 (8%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSE-----LNNQ 59
+ + AIVTG GIG I ++L++ G V+ KL L + AD+ +
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELGSNVV---IASRKLERLKSAADELQANLPPTKQAR 73
Query: 60 LIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+IP +C+I N+ ++ N + + +G ++ LVNN + + + V++ N+
Sbjct: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLT 133
Query: 120 GLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREE 179
G + S + G IVN+ +P+ + + V+ + R+ V+ T
Sbjct: 134 GTFYMCKAVYSSWMKEHGGSIVNI------IVPTKAGFPLAVHSGAARA-GVYNLTKSLA 186
Query: 180 LKMINSKIKITSVSPGIV--KTGI--FKSAGVGFIDDAF-FCDNSHLTV-KDVSEVILMI 233
L+ S I+I V+PG++ +T + + S G F + +F + V ++VS V+ +
Sbjct: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246
Query: 234 LS 235
LS
Sbjct: 247 LS 248
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 60
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 116
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 117 IVARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 170
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 171 KIRVNAVNPTVVMTSM 186
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 7 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 59
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 60 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 115
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 116 IVARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 169
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 170 KIRVNAVNPTVVMTSM 185
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 60
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 116
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 117 IVARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 170
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 171 KIRVNAVNPTVVMTSM 186
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 60
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 116
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 117 IVARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 170
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 171 KIRVNAVNPTVVMTSM 186
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 60
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 116
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 117 IVARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 170
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 171 KIRVNAVNPTVVMTSM 186
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 60
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 116
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 117 IVARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 170
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 171 KIRVNAVNPTVVMTSM 186
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 60
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 116
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 117 IVARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 170
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 171 KIRVNAVNPTVVMTSM 186
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/196 (28%), Positives = 87/196 (44%), Gaps = 18/196 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+ +VTGAG+GIG + L G V+ TQA L L P D
Sbjct: 8 RRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIE-------PVCVD 60
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A + G VDLLVNNAA+ E + +VN+ +I S+
Sbjct: 61 LGDWEATERALGSV----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQ 116
Query: 127 HAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ +G G IVNV+S C + +VY ++K ++ + TK + EL
Sbjct: 117 IVARGLIARGVPGAIVNVSSQCSQRAVTNH----SVYCSTKGALDMLTKVMALELG--PH 170
Query: 186 KIKITSVSPGIVKTGI 201
KI++ +V+P +V T +
Sbjct: 171 KIRVNAVNPTVVMTSM 186
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 58.0 bits (134), Expect = 3e-08
Identities = 53/198 (26%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +TG G G + + L+ GM V+ T+ L D L L+ D
Sbjct: 26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQR--DTSYRLQTTLL----D 79
Query: 67 ISNDNDLKNAFEGIVKLYG--GVDLLVNNAAIG-KAGMISTGNLEDLNNVIDVNIYGLIA 123
++ +K A + + G G+ LVNNA +G +G +D VI+VN+ GLI
Sbjct: 80 VTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ H + +K + +G +VN++S G + Y SK + F+ ++R EL
Sbjct: 140 VTLHMLPMVK-RARGRVVNMSSSGGRV-----AVIGGGYCVSKFGVEAFSDSIRRELYYF 193
Query: 184 NSKIKITSVSPGIVKTGI 201
+K+ + PG +T I
Sbjct: 194 G--VKVCIIEPGNYRTAI 209
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 58.0 bits (134), Expect = 3e-08
Identities = 53/198 (26%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +TG G G + + L+ GM V+ T+ L D L L+ D
Sbjct: 26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQR--DTSYRLQTTLL----D 79
Query: 67 ISNDNDLKNAFEGIVKLYG--GVDLLVNNAAIG-KAGMISTGNLEDLNNVIDVNIYGLIA 123
++ +K A + + G G+ LVNNA +G +G +D VI+VN+ GLI
Sbjct: 80 VTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ H + +K + +G +VN++S G + Y SK + F+ ++R EL
Sbjct: 140 VTLHMLPMVK-RARGRVVNMSSSGGRV-----AVIGGGYCVSKFGVEAFSDSIRRELYYF 193
Query: 184 NSKIKITSVSPGIVKTGI 201
+K+ + PG +T I
Sbjct: 194 G--VKVCIIEPGNYRTAI 209
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 58.0 bits (134), Expect = 3e-08
Identities = 53/198 (26%), Positives = 88/198 (44%), Gaps = 17/198 (8%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +TG G G + + L+ GM V+ T+ L D L L+ D
Sbjct: 26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQR--DTSYRLQTTLL----D 79
Query: 67 ISNDNDLKNAFEGIVKLYG--GVDLLVNNAAIG-KAGMISTGNLEDLNNVIDVNIYGLIA 123
++ +K A + + G G+ LVNNA +G +G +D VI+VN+ GLI
Sbjct: 80 VTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ H + +K + +G +VN++S G + Y SK + F+ ++R EL
Sbjct: 140 VTLHMLPMVK-RARGRVVNMSSSGGRV-----AVIGGGYCVSKFGVEAFSDSIRRELYYF 193
Query: 184 NSKIKITSVSPGIVKTGI 201
+K+ + PG +T I
Sbjct: 194 G--VKVCIIEPGNYRTAI 209
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 57.6 bits (133), Expect = 4e-08
Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
N+ A+VTG+ GIG I L + G V+ + K + K + C
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGAHVV---ISSRKQQNVDRAMAKLQGEGLSVAGIVC 92
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDL-NNVIDVNIYGLIAC 124
+ D + ++ GGVD LV +A + + G E + + ++ VN+
Sbjct: 93 HVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALL 152
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
+ M+N+ +G ++ V+SI Y P + + VY SK ++ T+TL L++
Sbjct: 153 LSQLLPYMENR-RGAVILVSSIAA-YNPVVA---LGVYNVSKTALLGLTRTL--ALELAP 205
Query: 185 SKIKITSVSPGIVKTGIFK 203
I++ V PGI+KT K
Sbjct: 206 KDIRVNCVVPGIIKTDFSK 224
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 57.6 bits (133), Expect = 4e-08
Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
N+ A+VTG+ GIG I L + G V+ + K + K + C
Sbjct: 27 NRVAVVTGSTSGIGFAIARRLARDGAHVV---ISSRKQQNVDRAMAKLQGEGLSVAGIVC 83
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDL-NNVIDVNIYGLIAC 124
+ D + ++ GGVD LV +A + + G E + + ++ VN+
Sbjct: 84 HVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALL 143
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
+ M+N+ +G ++ V+SI Y P + + VY SK ++ T+TL L++
Sbjct: 144 LSQLLPYMENR-RGAVILVSSIAA-YNPVVA---LGVYNVSKTALLGLTRTL--ALELAP 196
Query: 185 SKIKITSVSPGIVKTGIFK 203
I++ V PGI+KT K
Sbjct: 197 KDIRVNCVVPGIIKTDFSK 215
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 57.6 bits (133), Expect = 4e-08
Identities = 50/199 (25%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
N+ A+VTG+ GIG I L + G V+ + K + K + C
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGAHVV---ISSRKQQNVDRAMAKLQGEGLSVAGIVC 92
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDL-NNVIDVNIYGLIAC 124
+ D + ++ GGVD LV +A + + G E + + ++ VN+
Sbjct: 93 HVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPL 152
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
+ M+N+ +G ++ V+S+ Y P + + VY SK ++ T+TL L++
Sbjct: 153 LSQLLPYMENR-RGAVILVSSVAA-YNPVVA---LGVYSVSKTALLGLTRTL--ALELAP 205
Query: 185 SKIKITSVSPGIVKTGIFK 203
I++ V PGI+KT K
Sbjct: 206 KDIRVNCVVPGIIKTDFSK 224
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 57.6 bits (133), Expect = 4e-08
Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 11/199 (5%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
N+ A+VTG+ GIG I L + G V+ + K + K + C
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGAHVV---ISSRKQQNVDRAMAKLQGEGLSVAGIVC 92
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDL-NNVIDVNIYGLIAC 124
+ D + ++ GGVD LV +A + + G E + + ++ VN+
Sbjct: 93 HVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALL 152
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
+ M+N+ +G ++ V+SI Y P + + VY SK ++ T+TL L++
Sbjct: 153 LSQLLPYMENR-RGAVILVSSIAA-YNPVVA---LGVYNVSKTALLGLTRTL--ALELAP 205
Query: 185 SKIKITSVSPGIVKTGIFK 203
I++ V PGI+KT K
Sbjct: 206 KDIRVNCVVPGIIKTDFSK 224
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 56.4 bits (130), Expect = 9e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQL 60
+ H ++K +TG G G + L G+ V+ T+ L + +++L
Sbjct: 24 VSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQL------RGQTSDRL 77
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG--GVDLLVNNAAI-GKAGMISTGNLEDLNNVIDVN 117
D++ + A + + + G G+ LVNNA I + N ED N++ VN
Sbjct: 78 ETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVN 137
Query: 118 IYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLR 177
+ G+I + + ++ + +G IVNV+SI G +F + Y SK + F+ LR
Sbjct: 138 LIGVIQVTLSMLPLVR-RARGRIVNVSSILGRV--AF---FVGGYCVSKYGVEAFSDILR 191
Query: 178 EELKMINSKIKITSVSPGIVKTGI 201
E++ +KI+ V PG +TG+
Sbjct: 192 REIQHFG--VKISIVEPGYFRTGM 213
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 56.4 bits (130), Expect = 9e-08
Identities = 45/206 (21%), Positives = 91/206 (44%), Gaps = 11/206 (5%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+KA +VTG G G + + L G V F K + + S +++L +
Sbjct: 55 SKAVLVTGCDSGFGFSLAKHLHSKGFLV--FAGCLMKDKGHDGVKELDSLNSDRLRTVQL 112
Query: 66 DISNDNDLKNAFE----GIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
++ + +++ E + G+ LVNNA I G + +LE V +VN++G
Sbjct: 113 NVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGT 172
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ + KG +VN++S+ G + P + Y +K + F+ LR E+
Sbjct: 173 VRMTKSFLPLIR-RAKGRVVNISSMLGR----MANPARSPYCITKFGVEAFSDCLRYEMY 227
Query: 182 MINSKIKITSVSPGIVKTGIFKSAGV 207
+ K+ + I T ++ +
Sbjct: 228 PLGVKVSVVEPGNFIAATSLYSPESI 253
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 56.4 bits (130), Expect = 9e-08
Identities = 45/206 (21%), Positives = 91/206 (44%), Gaps = 11/206 (5%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+KA +VTG G G + + L G V F K + + S +++L +
Sbjct: 55 SKAVLVTGCDSGFGFSLAKHLHSKGFLV--FAGCLMKDKGHDGVKELDSLNSDRLRTVQL 112
Query: 66 DISNDNDLKNAFE----GIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
++ + +++ E + G+ LVNNA I G + +LE V +VN++G
Sbjct: 113 NVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGT 172
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ + KG +VN++S+ G + P + Y +K + F+ LR E+
Sbjct: 173 VRMTKSFLPLIR-RAKGRVVNISSMLGR----MANPARSPYCITKFGVEAFSDCLRYEMY 227
Query: 182 MINSKIKITSVSPGIVKTGIFKSAGV 207
+ K+ + I T ++ +
Sbjct: 228 PLGVKVSVVEPGNFIAATSLYSPESI 253
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 56.4 bits (130), Expect = 9e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQL 60
+ H ++K +TG G G + L G+ V+ T+ L + +++L
Sbjct: 24 VSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQL------RGQTSDRL 77
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG--GVDLLVNNAAI-GKAGMISTGNLEDLNNVIDVN 117
D++ + A + + + G G+ LVNNA I + N ED N++ VN
Sbjct: 78 ETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVN 137
Query: 118 IYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLR 177
+ G+I + + ++ + +G IVNV+SI G +F + Y SK + F+ LR
Sbjct: 138 LIGVIQVTLSMLPLVR-RARGRIVNVSSILGRV--AF---FVGGYCVSKYGVEAFSDILR 191
Query: 178 EELKMINSKIKITSVSPGIVKTGI 201
E++ +KI+ V PG +TG+
Sbjct: 192 REIQHFG--VKISIVEPGYFRTGM 213
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 56.4 bits (130), Expect = 9e-08
Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 17/204 (8%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQL 60
+ H ++K +TG G G + L G+ V+ T+ L + +++L
Sbjct: 24 VSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQL------RGQTSDRL 77
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG--GVDLLVNNAAI-GKAGMISTGNLEDLNNVIDVN 117
D++ + A + + + G G+ LVNNA I + N ED N++ VN
Sbjct: 78 ETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVN 137
Query: 118 IYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLR 177
+ G+I + + ++ + +G IVNV+SI G +F + Y SK + F+ LR
Sbjct: 138 LIGVIQVTLSMLPLVR-RARGRIVNVSSILGRV--AF---FVGGYCVSKYGVEAFSDILR 191
Query: 178 EELKMINSKIKITSVSPGIVKTGI 201
E++ +KI+ V PG +TG+
Sbjct: 192 REIQHFG--VKISIVEPGYFRTGM 213
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 56.0 bits (129), Expect = 1e-07
Identities = 45/206 (21%), Positives = 91/206 (44%), Gaps = 11/206 (5%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+KA +VTG G G + + L G V F K + + S +++L +
Sbjct: 55 SKAVLVTGCDSGFGFALAKHLHSKGFLV--FAGCLMKDKGHDGVKELDSLNSDRLRTVQL 112
Query: 66 DISNDNDLKNAFE----GIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
++ + +++ E + G+ LVNNA I G + +LE V +VN++G
Sbjct: 113 NVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGT 172
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ + KG +VN++S+ G + P + Y +K + F+ LR E+
Sbjct: 173 VRMTKSFLPLIR-RAKGRVVNISSMLGR----MANPARSPYCITKFGVEAFSDCLRYEMY 227
Query: 182 MINSKIKITSVSPGIVKTGIFKSAGV 207
+ K+ + I T ++ +
Sbjct: 228 PLGVKVSVVEPGNFIAATSLYSPESI 253
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 55.6 bits (128), Expect = 2e-07
Identities = 58/242 (23%), Positives = 110/242 (45%), Gaps = 21/242 (8%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSE-----LNNQ 59
+ + A VTG GIG I ++L++ G V+ KL L + AD+ +
Sbjct: 17 QGQVAFVTGGATGIGKAIVKELLELGSNVV---IASRKLERLKSAADELQANLPPTKQAR 73
Query: 60 LIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+IP +C+I N+ ++ N + + +G ++ LVNN + + + V+ N+
Sbjct: 74 VIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLT 133
Query: 120 GLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREE 179
G + S + G IVN+ +P+ + + V+ + R+ V+ T
Sbjct: 134 GSFYMCKAVYSSWMKEHGGSIVNI------IVPTKAGFPLAVHSGAARA-GVYNLTKSLA 186
Query: 180 LKMINSKIKITSVSPGIV--KTGI--FKSAGVGFIDDAF-FCDNSHLTV-KDVSEVILMI 233
L+ S I+I V+PG++ +T + + S G F + +F + V ++VS V+ +
Sbjct: 187 LEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFL 246
Query: 234 LS 235
LS
Sbjct: 247 LS 248
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/152 (28%), Positives = 67/152 (44%), Gaps = 5/152 (3%)
Query: 57 NNQLIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDV 116
N Q+ CD+ ++ E + K G V +LVNNA + + E + + V
Sbjct: 109 NLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMV 168
Query: 117 NIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
N + ++ + +M GHIV V S G FS + Y ASK + F ++L
Sbjct: 169 NCHAHFWTTKAFLPTMLEINHGHIVTVASSLG----LFSTAGVEDYCASKFGVVGFHESL 224
Query: 177 REELKMINSK-IKITSVSPGIVKTGIFKSAGV 207
ELK IK T V P +V TG+F+ +
Sbjct: 225 SHELKAAEKDGIKTTLVCPYLVDTGMFRGCRI 256
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/152 (28%), Positives = 67/152 (44%), Gaps = 5/152 (3%)
Query: 57 NNQLIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDV 116
N Q+ CD+ ++ E + K G V +LVNNA + + E + + V
Sbjct: 109 NLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMV 168
Query: 117 NIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
N + ++ + +M GHIV V S G FS + Y ASK + F ++L
Sbjct: 169 NCHAHFWTTKAFLPTMLEINHGHIVTVASSLG----LFSTAGVEDYCASKFGVVGFHESL 224
Query: 177 REELKMINSK-IKITSVSPGIVKTGIFKSAGV 207
ELK IK T V P +V TG+F+ +
Sbjct: 225 SHELKAAEKDGIKTTLVCPYLVDTGMFRGCRI 256
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 54.8 bits (126), Expect = 3e-07
Identities = 44/152 (28%), Positives = 67/152 (44%), Gaps = 5/152 (3%)
Query: 57 NNQLIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDV 116
N Q+ CD+ ++ E + K G V +LVNNA + + E + + V
Sbjct: 109 NLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMV 168
Query: 117 NIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
N + ++ + +M GHIV V S G FS + Y ASK + F ++L
Sbjct: 169 NCHAHFWTTKAFLPTMLEINHGHIVTVASSLG----LFSTAGVEDYCASKFGVVGFHESL 224
Query: 177 REELKMINSK-IKITSVSPGIVKTGIFKSAGV 207
ELK IK T V P +V TG+F+ +
Sbjct: 225 SHELKAAEKDGIKTTLVCPYLVDTGMFRGCRI 256
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 54.4 bits (125), Expect = 4e-07
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 9/207 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+ K IVTGA +GIG ++ L K G V+ T L + EL
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVV---VTARSKETLQKVVSHCLELGAASAHYI 89
Query: 65 CDISNDNDLKNAFEGIV-KLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIA 123
D F KL GG+D+L+ N + + ++ + ++VN +
Sbjct: 90 AGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVV 149
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ A+ +K + G IV V+S+ G + P++ Y ASK ++ F ++R+E +
Sbjct: 150 LTVAALPMLK-QSNGSIVVVSSLAG----KVAYPMVAAYSASKFALDGFFSSIRKEYSVS 204
Query: 184 NSKIKITSVSPGIVKTGIFKSAGVGFI 210
+ IT G++ T A G +
Sbjct: 205 RVNVSITLCVLGLIDTETAMKAVSGIV 231
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 54.4 bits (125), Expect = 4e-07
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 9/207 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+ K IVTGA +GIG ++ L K G V+ T L + EL
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVV---VTARSKETLQKVVSHCLELGAASAHYI 89
Query: 65 CDISNDNDLKNAFEGIV-KLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIA 123
D F KL GG+D+L+ N + + ++ + ++VN +
Sbjct: 90 AGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVV 149
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ A+ +K + G IV V+S+ G + P++ Y ASK ++ F ++R+E +
Sbjct: 150 LTVAALPMLK-QSNGSIVVVSSLAG----KVAYPMVAAYSASKFALDGFFSSIRKEYSVS 204
Query: 184 NSKIKITSVSPGIVKTGIFKSAGVGFI 210
+ IT G++ T A G +
Sbjct: 205 RVNVSITLCVLGLIDTETAMKAVSGIV 231
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 54.4 bits (125), Expect = 4e-07
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 9/207 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+ K IVTGA +GIG ++ L K G V+ T L + EL
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVV---VTARSKETLQKVVSHCLELGAASAHYI 89
Query: 65 CDISNDNDLKNAFEGIV-KLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIA 123
D F KL GG+D+L+ N + + ++ + ++VN +
Sbjct: 90 AGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVV 149
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ A+ +K + G IV V+S+ G + P++ Y ASK ++ F ++R+E +
Sbjct: 150 LTVAALPMLK-QSNGSIVVVSSLAG----KVAYPMVAAYSASKFALDGFFSSIRKEYSVS 204
Query: 184 NSKIKITSVSPGIVKTGIFKSAGVGFI 210
+ IT G++ T A G +
Sbjct: 205 RVNVSITLCVLGLIDTETAMKAVSGIV 231
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 54.4 bits (125), Expect = 4e-07
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 9/207 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+ K IVTGA +GIG ++ L K G V+ T L + EL
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVV---VTARSKETLQKVVSHCLELGAASAHYI 89
Query: 65 CDISNDNDLKNAFEGIV-KLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIA 123
D F KL GG+D+L+ N + + ++ + ++VN +
Sbjct: 90 AGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVV 149
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ A+ +K + G IV V+S+ G + P++ Y ASK ++ F ++R+E +
Sbjct: 150 LTVAALPMLK-QSNGSIVVVSSLAG----KVAYPMVAAYSASKFALDGFFSSIRKEYSVS 204
Query: 184 NSKIKITSVSPGIVKTGIFKSAGVGFI 210
+ IT G++ T A G +
Sbjct: 205 RVNVSITLCVLGLIDTETAMKAVSGIV 231
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 54.4 bits (125), Expect = 4e-07
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 9/207 (4%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+ K IVTGA +GIG ++ L K G V+ T L + EL
Sbjct: 33 QGKKVIVTGASKGIGREMAYHLAKMGAHVV---VTARSKETLQKVVSHCLELGAASAHYI 89
Query: 65 CDISNDNDLKNAFEGIV-KLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIA 123
D F KL GG+D+L+ N + + ++ + ++VN +
Sbjct: 90 AGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVV 149
Query: 124 CSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMI 183
+ A+ +K + G IV V+S+ G + P++ Y ASK ++ F ++R+E +
Sbjct: 150 LTVAALPMLK-QSNGSIVVVSSLAG----KVAYPMVAAYSASKFALDGFFSSIRKEYSVS 204
Query: 184 NSKIKITSVSPGIVKTGIFKSAGVGFI 210
+ IT G++ T A G +
Sbjct: 205 RVNVSITLCVLGLIDTETAMKAVSGIV 231
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 53.2 bits (122), Expect = 8e-07
Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 5/118 (4%)
Query: 90 LVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGH 149
LVNNA I G + +LE V +VN++G + ++ + ++ + KG +VN++S+ G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIR-RAKGRVVNISSMLGR 199
Query: 150 YMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGIVKTGIFKSAGV 207
+ P + Y +K + F+ LR E+ + K+ + I T ++ +
Sbjct: 200 ----MANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLYNPESI 253
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 52.8 bits (121), Expect = 1e-06
Identities = 48/204 (23%), Positives = 87/204 (42%), Gaps = 17/204 (8%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQL 60
+ H ++K +TG G G + L G+ V+ T+ L + +++L
Sbjct: 24 LSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQL------RGQTSDRL 77
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDL--LVNNAAIG-KAGMISTGNLEDLNNVIDVN 117
D++ + A + + + L LVNNA I +D ++DVN
Sbjct: 78 ETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVN 137
Query: 118 IYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLR 177
+ G+I + + ++ K +G +VNV+S+ G + F Y SK + F+ +LR
Sbjct: 138 LLGVIDVTLSLLPLVR-KARGRVVNVSSVMGR-VSLFG----GGYCISKYGVEAFSDSLR 191
Query: 178 EELKMINSKIKITSVSPGIVKTGI 201
EL +K+ + PG KT +
Sbjct: 192 RELSYFG--VKVAMIEPGYFKTAV 213
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 52.4 bits (120), Expect = 1e-06
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 12/196 (6%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGM-TVIGFEPTQAKLTPLFNLADKYSELNNQL 60
D ++K A +TG G GIG +I E ++ G TVI LT LA +
Sbjct: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA---GATGRRC 80
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYG 120
+P D+ + A + +K +G +D+L+N AA + V+D++ G
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIAS-KRSMTVFTKTLREE 179
SR + G IVN+ + G+ + V+ S K ++ T+ L E
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGN-----RGQALQVHAGSAKAAVDAMTRHLAVE 195
Query: 180 LKMINSKIKITSVSPG 195
N I++ S++PG
Sbjct: 196 WGPQN--IRVNSLAPG 209
>AL023881-2|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 52.4 bits (120), Expect = 1e-06
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 12/196 (6%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGM-TVIGFEPTQAKLTPLFNLADKYSELNNQL 60
D ++K A +TG G GIG +I E ++ G TVI LT LA +
Sbjct: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA---GATGRRC 80
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYG 120
+P D+ + A + +K +G +D+L+N AA + V+D++ G
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIAS-KRSMTVFTKTLREE 179
SR + G IVN+ + G+ + V+ S K ++ T+ L E
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGN-----RGQALQVHAGSAKAAVDAMTRHLAVE 195
Query: 180 LKMINSKIKITSVSPG 195
N I++ S++PG
Sbjct: 196 WGPQN--IRVNSLAPG 209
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 52.4 bits (120), Expect = 1e-06
Identities = 46/203 (22%), Positives = 86/203 (42%), Gaps = 7/203 (3%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
++ ++TG G+GIG Q+ + + G I K L ++ ++ + CD
Sbjct: 39 ESVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKC--LKETTEEIRQMGTECHYFICD 96
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ N ++ + + + G + +LVNNAA+ + + + L +N G ++
Sbjct: 97 VGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTK 156
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSK 186
+ M GHIV +NS+ + + P Y SK S F ++L L +
Sbjct: 157 AFLPRMLELQNGHIVCLNSV----LALSAIPGAIDYCTSKASAFAFMESLTLGL-LDCPG 211
Query: 187 IKITSVSPGIVKTGIFKSAGVGF 209
+ T+V P T +F+ V F
Sbjct: 212 VSATTVLPFHTSTEMFQGMRVRF 234
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 52.4 bits (120), Expect = 1e-06
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 12/196 (6%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGM-TVIGFEPTQAKLTPLFNLADKYSELNNQL 60
D ++K A +TG G GIG +I E ++ G TVI LT LA +
Sbjct: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA---GATGRRC 80
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYG 120
+P D+ + A + +K +G +D+L+N AA + V+D++ G
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIAS-KRSMTVFTKTLREE 179
SR + G IVN+ + G+ + V+ S K ++ T+ L E
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGN-----RGQALQVHAGSAKAAVDAMTRHLAVE 195
Query: 180 LKMINSKIKITSVSPG 195
N I++ S++PG
Sbjct: 196 WGPQN--IRVNSLAPG 209
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 52.4 bits (120), Expect = 1e-06
Identities = 48/204 (23%), Positives = 88/204 (43%), Gaps = 17/204 (8%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQL 60
+ H ++K +TG G G + L G+ V+ T+ L + +++L
Sbjct: 24 LSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQL------RGQTSDRL 77
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDL--LVNNAAIG-KAGMISTGNLEDLNNVIDVN 117
D++ + A + + + L LVNNA I +DL ++DVN
Sbjct: 78 ETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGISLPTAPNELLTKQDLLTILDVN 137
Query: 118 IYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLR 177
+ G+I + + + ++ + +G +VNV S+ G + F Y SK + F+ +LR
Sbjct: 138 LLGVIDVTLNLLPLVR-RARGRVVNVFSVMGR-VSLFG----GGYCISKYGVEAFSDSLR 191
Query: 178 EELKMINSKIKITSVSPGIVKTGI 201
EL +K+ + PG KT +
Sbjct: 192 RELSYFG--VKVAMIEPGYFKTAV 213
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 52.4 bits (120), Expect = 1e-06
Identities = 50/196 (25%), Positives = 83/196 (42%), Gaps = 12/196 (6%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGM-TVIGFEPTQAKLTPLFNLADKYSELNNQL 60
D ++K A +TG G GIG +I E ++ G TVI LT LA +
Sbjct: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLA---GATGRRC 80
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYG 120
+P D+ + A + +K +G +D+L+N AA + V+D++ G
Sbjct: 81 LPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSG 140
Query: 121 LIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIAS-KRSMTVFTKTLREE 179
SR + G IVN+ + G+ + V+ S K ++ T+ L E
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLGN-----RGQALQVHAGSAKAAVDAMTRHLAVE 195
Query: 180 LKMINSKIKITSVSPG 195
N I++ S++PG
Sbjct: 196 WGPQN--IRVNSLAPG 209
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 26/213 (12%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNVYIASKRSMTV 171
G R M ++G +G I+N S+ +F V Y ASK +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAAYSASKGGIVG 177
Query: 172 FTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
T + +L I I++ +++PG+ T + S
Sbjct: 178 MTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 208
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 26/213 (12%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNVYIASKRSMTV 171
G R M ++G +G I+N S+ +F V Y ASK +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAAYSASKGGIVG 177
Query: 172 FTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
T + +L I I++ +++PG+ T + S
Sbjct: 178 MTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 208
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 26/213 (12%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNVYIASKRSMTV 171
G R M ++G +G I+N S+ +F V Y ASK +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAAYSASKGGIVG 177
Query: 172 FTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
T + +L I I++ +++PG+ T + S
Sbjct: 178 MTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 208
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 52.0 bits (119), Expect = 2e-06
Identities = 58/239 (24%), Positives = 98/239 (41%), Gaps = 14/239 (5%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNL----ADKYSELNNQL 60
++ A+VTGAG GIG ++ L G TV + +A L K
Sbjct: 8 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 67
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG-GVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+ D+S + E + + ++V+ A I + + + +D + VI VN+
Sbjct: 68 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSRDDWDKVIAVNLK 127
Query: 120 GLIACSRHAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
G ++ A ++ + G +G I+N++SI G Y ASK + T+T
Sbjct: 128 GTFLVTQAAAQALVSNGCRGSIINISSIVG----KVGNVGQTNYAASKAGVIGLTQTAAR 183
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKSAGVGFIDD-AFFCDNSHL-TVKDVSEVILMILS 235
EL I SV PG + T + K +D HL +DV++V+ + S
Sbjct: 184 ELG--RHGIPCNSVLPGFIATPMTKKVPKKVVDKITEMIPMGHLGDPEDVADVVAFLAS 240
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 26/213 (12%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNVYIASKRSMTV 171
G R M ++G +G I+N S+ +F V Y ASK +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAAYSASKGGIVG 177
Query: 172 FTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
T + +L I I++ +++PG+ T + S
Sbjct: 178 MTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 208
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 52.0 bits (119), Expect = 2e-06
Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
++ AIVTG GIG + L + GM VI +K + + K LN+++ C
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKI-KEETLNDKVEFLYC 101
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+++ ++ + + +L+NNA + T + +N G +
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTR--DGFEEHFGLNYLGHFLLT 159
Query: 126 RHAIDSMKNKGK-GHIVNVNSICG--HYMPSFSEPVMN---------VYIASKRSMTVFT 173
+D++K G GH V ++ HY+ + + Y SK ++ +FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 174 KTLREELKMINSKIKITSVSPGIVKTGIFK 203
L+ L S + V PG+V T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVYK 249
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 52.0 bits (119), Expect = 2e-06
Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
++ AIVTG GIG + L + GM VI +K + + K LN+++ C
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKI-KEETLNDKVEFLYC 101
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+++ ++ + + +L+NNA + T + +N G +
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTR--DGFEEHFGLNYLGHFLLT 159
Query: 126 RHAIDSMKNKGK-GHIVNVNSICG--HYMPSFSEPVMN---------VYIASKRSMTVFT 173
+D++K G GH V ++ HY+ + + Y SK ++ +FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 174 KTLREELKMINSKIKITSVSPGIVKTGIFK 203
L+ L S + V PG+V T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVYK 249
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 52.0 bits (119), Expect = 2e-06
Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
++ AIVTG GIG + L + GM VI +K + + K LN+++ C
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKI-KEETLNDKVEFLYC 101
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+++ ++ + + +L+NNA + T + +N G +
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTR--DGFEEHFGLNYLGHFLLT 159
Query: 126 RHAIDSMKNKGK-GHIVNVNSICG--HYMPSFSEPVMN---------VYIASKRSMTVFT 173
+D++K G GH V ++ HY+ + + Y SK ++ +FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 174 KTLREELKMINSKIKITSVSPGIVKTGIFK 203
L+ L S + V PG+V T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVYK 249
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 26/213 (12%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNVYIASKRSMTV 171
G R M ++G +G I+N S+ +F V Y ASK +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAAYSASKGGIVG 177
Query: 172 FTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
T + +L I I++ +++PG+ T + S
Sbjct: 178 MTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 208
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 52.0 bits (119), Expect = 2e-06
Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
++ AIVTG GIG + L + GM VI +K + + K LN+++ C
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKI-KEETLNDKVEFLYC 101
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+++ ++ + + +L+NNA + T + +N G +
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTR--DGFEEHFGLNYLGHFLLT 159
Query: 126 RHAIDSMKNKGK-GHIVNVNSICG--HYMPSFSEPVMN---------VYIASKRSMTVFT 173
+D++K G GH V ++ HY+ + + Y SK ++ +FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 174 KTLREELKMINSKIKITSVSPGIVKTGIFK 203
L+ L S + V PG+V T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVYK 249
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 15/179 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
+K +TG G G K G VI T++ T L +E + +L
Sbjct: 29 DKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTAL------KAETSERLRTVLL 82
Query: 66 DISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++K + + G L L+NNA + G LED I+VN++GLI
Sbjct: 83 DVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLI 142
Query: 123 ACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ + + + +K K +G ++NV+S+ G V Y SK ++ F +LR ++K
Sbjct: 143 SVTLNMLPLVK-KAQGRVINVSSVGGRL-----AIVGGGYTPSKYAVEGFNDSLRRDMK 195
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 26/213 (12%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNVYIASKRSMTV 171
G R M ++G +G I+N S+ +F V Y ASK +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAAYSASKGGIVG 177
Query: 172 FTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
T + +L I I++ +++PG+ T + S
Sbjct: 178 MTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 208
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 26/213 (12%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNVYIASKRSMTV 171
G R M ++G +G I+N S+ +F V Y ASK +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAAYSASKGGIVG 177
Query: 172 FTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
T + +L I I++ +++PG+ T + S
Sbjct: 178 MTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 208
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 52.0 bits (119), Expect = 2e-06
Identities = 53/213 (24%), Positives = 89/213 (41%), Gaps = 26/213 (12%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNVYIASKRSMTV 171
G R M ++G +G I+N S+ +F V Y ASK +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAAYSASKGGIVG 177
Query: 172 FTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
T + +L I I++ +++PG+ T + S
Sbjct: 178 MTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 208
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +VTGA GIG + ++L + G V + L + + N Q++ K D
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVY-LACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+S+ ++ +G + + +L+NNA + T + +++ I VN G +
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGVNHLGHFLLTH 158
Query: 127 HAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRSMTVFTKTLRE 178
++ +K IVNV+S+ H+ E N Y SK + +FT+ L
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 179 ELKMINSKIKITSVSPGIVKTGIFK 203
LK S + SV PG V++ + +
Sbjct: 219 RLK--GSGVTTYSVHPGTVQSELVR 241
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +VTGA GIG + ++L + G V + L + + N Q++ K D
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVY-LACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+S+ ++ +G + + +L+NNA + T + +++ I VN G +
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGVNHLGHFLLTH 158
Query: 127 HAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRSMTVFTKTLRE 178
++ +K IVNV+S+ H+ E N Y SK + +FT+ L
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 179 ELKMINSKIKITSVSPGIVKTGIFK 203
LK S + SV PG V++ + +
Sbjct: 219 RLK--GSGVTTYSVHPGTVQSELVR 241
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
++ AIVTG GIG + L + GM VI +K + + K LN+++ C
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKI-KEETLNDKVEFLYC 101
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+++ ++ + + +L+NNA + T + +N G +
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTR--DGFEEHFGLNYLGHFLLT 159
Query: 126 RHAIDSMKNKGK-GHIVNVNSICG--HYMPSFSEPVMN---------VYIASKRSMTVFT 173
+D++K G GH V ++ HY+ + + Y SK ++ +FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 174 KTLREELKMINSKIKITSVSPGIVKTGIFK 203
L+ L S + V PG+V T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDLYK 249
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +VTGA GIG + ++L + G V + L + + N Q++ K D
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVY-LACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+S+ ++ +G + + +L+NNA + T + +++ I VN G +
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGVNHLGHFLLTH 158
Query: 127 HAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRSMTVFTKTLRE 178
++ +K IVNV+S+ H+ E N Y SK + +FT+ L
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 179 ELKMINSKIKITSVSPGIVKTGIFK 203
LK S + SV PG V++ + +
Sbjct: 219 RLK--GSGVTTYSVHPGTVQSELVR 241
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +VTGA GIG + ++L + G V + L + + N Q++ K D
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVY-LACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+S+ ++ +G + + +L+NNA + T + +++ I VN G +
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGVNHLGHFLLTH 158
Query: 127 HAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRSMTVFTKTLRE 178
++ +K IVNV+S+ H+ E N Y SK + +FT+ L
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 179 ELKMINSKIKITSVSPGIVKTGIFK 203
LK S + SV PG V++ + +
Sbjct: 219 RLK--GSGVTTYSVHPGTVQSELVR 241
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/200 (23%), Positives = 84/200 (42%), Gaps = 7/200 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TG G+GIG Q+ + + G I K L ++ ++ + CD+ N
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKC--LKETTEEIRQMGTECHYFICDVGN 99
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
++ + + + G + +LVNNAA+ + + + L +N G ++ +
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M GHIV +NS+ + + P Y SK S F ++L L + +
Sbjct: 160 PRMLELQNGHIVCLNSV----LALSAIPGAIDYCTSKASAFAFMESLTLGL-LDCPGVSA 214
Query: 190 TSVSPGIVKTGIFKSAGVGF 209
T+V P T +F+ V F
Sbjct: 215 TTVLPFHTSTEMFQGMRVRF 234
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +VTGA GIG + ++L + G V + L + + N Q++ K D
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVY-LACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+S+ ++ +G + + +L+NNA + T + +++ I VN G +
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGVNHLGHFLLTH 158
Query: 127 HAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRSMTVFTKTLRE 178
++ +K IVNV+S+ H+ E N Y SK + +FT+ L
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 179 ELKMINSKIKITSVSPGIVKTGIFK 203
LK S + SV PG V++ + +
Sbjct: 219 RLK--GSGVTTYSVHPGTVQSELVR 241
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/200 (23%), Positives = 84/200 (42%), Gaps = 7/200 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TG G+GIG Q+ + + G I K L ++ ++ + CD+ N
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKC--LKETTEEIRQMGTECHYFICDVGN 99
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
++ + + + G + +LVNNAA+ + + + L +N G ++ +
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M GHIV +NS+ + + P Y SK S F ++L L + +
Sbjct: 160 PRMLELQNGHIVCLNSV----LALSAIPGAIDYCTSKASAFAFMESLTLGL-LDCPGVSA 214
Query: 190 TSVSPGIVKTGIFKSAGVGF 209
T+V P T +F+ V F
Sbjct: 215 TTVLPFHTSTEMFQGMRVRF 234
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/200 (23%), Positives = 84/200 (42%), Gaps = 7/200 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TG G+GIG Q+ + + G I K L ++ ++ + CD+ N
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKC--LKETTEEIRQMGTECHYFICDVGN 99
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
++ + + + G + +LVNNAA+ + + + L +N G ++ +
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M GHIV +NS+ + + P Y SK S F ++L L + +
Sbjct: 160 PRMLELQNGHIVCLNSV----LALSAIPGAIDYCTSKASAFAFMESLTLGL-LDCPGVSA 214
Query: 190 TSVSPGIVKTGIFKSAGVGF 209
T+V P T +F+ V F
Sbjct: 215 TTVLPFHTSTEMFQGMRVRF 234
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 51.6 bits (118), Expect = 3e-06
Identities = 48/210 (22%), Positives = 87/210 (41%), Gaps = 15/210 (7%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
++ AIVTG GIG + L + GM VI +K + + K LN+++ C
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKI-KEETLNDKVEFLYC 101
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+++ ++ + + +L+NNA + T + +N G +
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTR--DGFEEHFGLNYLGHFLLT 159
Query: 126 RHAIDSMKNKGK-GHIVNVNSICG--HYMPSFSEPVMN---------VYIASKRSMTVFT 173
+D++K G GH V ++ HY+ + + Y SK ++ +FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 174 KTLREELKMINSKIKITSVSPGIVKTGIFK 203
L+ L S + V PG+V T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDLYK 249
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +VTGA GIG + ++L + G V + L + + N Q++ K D
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVY-LACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+S+ ++ +G + + +L+NNA + T + +++ I VN G +
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGVNHLGHFLLTH 158
Query: 127 HAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRSMTVFTKTLRE 178
++ +K IVNV+S+ H+ E N Y SK + +FT+ L
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 179 ELKMINSKIKITSVSPGIVKTGIFK 203
LK S + SV PG V++ + +
Sbjct: 219 RLK--GSGVTTYSVHPGTVQSELVR 241
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/200 (23%), Positives = 84/200 (42%), Gaps = 7/200 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TG G+GIG Q+ + + G I K L ++ ++ + CD+ N
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKC--LKETTEEIRQMGTECHYFICDVGN 99
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
++ + + + G + +LVNNAA+ + + + L +N G ++ +
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M GHIV +NS+ + + P Y SK S F ++L L + +
Sbjct: 160 PRMLELQNGHIVCLNSV----LALSAIPGAIDYCTSKASAFAFMESLTLGL-LDCPGVSA 214
Query: 190 TSVSPGIVKTGIFKSAGVGF 209
T+V P T +F+ V F
Sbjct: 215 TTVLPFHTSTEMFQGMRVRF 234
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +VTGA GIG + ++L + G V + L + + N Q++ K D
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVY-LACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+S+ ++ +G + + +L+NNA + T + +++ I VN G +
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGVNHLGHFLLTH 158
Query: 127 HAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRSMTVFTKTLRE 178
++ +K IVNV+S+ H+ E N Y SK + +FT+ L
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 179 ELKMINSKIKITSVSPGIVKTGIFK 203
LK S + SV PG V++ + +
Sbjct: 219 RLK--GSGVTTYSVHPGTVQSELVR 241
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 13/205 (6%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
K +VTGA GIG + ++L + G V + L + + N Q++ K D
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVY-LACRDVEKGELVAKEIQTTTGNQQVLVRKLD 100
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+S+ ++ +G + + +L+NNA + T + +++ I VN G +
Sbjct: 101 LSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGVNHLGHFLLTH 158
Query: 127 HAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRSMTVFTKTLRE 178
++ +K IVNV+S+ H+ E N Y SK + +FT+ L
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQELAR 218
Query: 179 ELKMINSKIKITSVSPGIVKTGIFK 203
LK S + SV PG V++ + +
Sbjct: 219 RLK--GSGVTTYSVHPGTVQSELVR 241
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/200 (23%), Positives = 84/200 (42%), Gaps = 7/200 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TG G+GIG Q+ + + G I K L ++ ++ + CD+ N
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKC--LKETTEEIRQMGTECHYFICDVGN 99
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
++ + + + G + +LVNNAA+ + + + L +N G ++ +
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFL 159
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
M GHIV +NS+ + + P Y SK S F ++L L + +
Sbjct: 160 PRMLELQNGHIVCLNSV----LALSAIPGAIDYCTSKASAFAFMESLTLGL-LDCPGVSA 214
Query: 190 TSVSPGIVKTGIFKSAGVGF 209
T+V P T +F+ V F
Sbjct: 215 TTVLPFHTSTEMFQGMRVRF 234
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 14/239 (5%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNL----ADKYSELNNQL 60
++ A+VTGAG GIG ++ L G TV + +A L K
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG-GVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+ D+S + E + + ++V+ A I + + + +D + VI VN+
Sbjct: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129
Query: 120 GLIACSRHAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
G ++ A ++ + G +G I+N++SI G Y ASK + T+T
Sbjct: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVG----KVGNVGQTNYAASKAGVIGLTQTAAR 185
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKSAGVGFIDD-AFFCDNSHL-TVKDVSEVILMILS 235
EL I+ SV PG + T + + +D HL +DV++V+ + S
Sbjct: 186 ELG--RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 14/239 (5%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNL----ADKYSELNNQL 60
++ A+VTGAG GIG ++ L G TV + +A L K
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG-GVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+ D+S + E + + ++V+ A I + + + +D + VI VN+
Sbjct: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129
Query: 120 GLIACSRHAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
G ++ A ++ + G +G I+N++SI G Y ASK + T+T
Sbjct: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVG----KVGNVGQTNYAASKAGVIGLTQTAAR 185
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKSAGVGFIDD-AFFCDNSHL-TVKDVSEVILMILS 235
EL I+ SV PG + T + + +D HL +DV++V+ + S
Sbjct: 186 ELG--RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 51.2 bits (117), Expect = 3e-06
Identities = 49/214 (22%), Positives = 93/214 (43%), Gaps = 22/214 (10%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVI----GFEPTQAKLTPLFNLADKYSELNNQLIP 62
K IVTGA GIG Q +L + G +I E +A + + LN+ +
Sbjct: 39 KTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDI-----RGETLNHHVNA 93
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++ I++ VD+L+NNA + + +T + ++ VN G
Sbjct: 94 RHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQ--FGVNHLGHF 151
Query: 123 ACSRHAIDSMKNKGKGHIVNVNS---ICGHY------MPSFSEPVMNVYIASKRSMTVFT 173
+ +D +K I+N++S + GH + Y SK ++ +FT
Sbjct: 152 LLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFT 211
Query: 174 KTLREELKMINSKIKITSVSPGIVKTGIFKSAGV 207
K L L+ S + + ++ PG+ +T + + G+
Sbjct: 212 KELSRRLQ--GSGVTVNALHPGVARTELGRHTGI 243
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 14/239 (5%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNL----ADKYSELNNQL 60
++ A+VTGAG GIG ++ L G TV + +A L K
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG-GVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+ D+S + E + + ++V+ A I + + + +D + VI VN+
Sbjct: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129
Query: 120 GLIACSRHAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
G ++ A ++ + G +G I+N++SI G Y ASK + T+T
Sbjct: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVG----KVGNVGQTNYAASKAGVIGLTQTAAR 185
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKSAGVGFIDD-AFFCDNSHL-TVKDVSEVILMILS 235
EL I+ SV PG + T + + +D HL +DV++V+ + S
Sbjct: 186 ELG--RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 14/239 (5%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNL----ADKYSELNNQL 60
++ A+VTGAG GIG ++ L G TV + +A L K
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG-GVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+ D+S + E + + ++V+ A I + + + +D + VI VN+
Sbjct: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129
Query: 120 GLIACSRHAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
G ++ A ++ + G +G I+N++SI G Y ASK + T+T
Sbjct: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVG----KVGNVGQTNYAASKAGVIGLTQTAAR 185
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKSAGVGFIDD-AFFCDNSHL-TVKDVSEVILMILS 235
EL I+ SV PG + T + + +D HL +DV++V+ + S
Sbjct: 186 ELG--RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 14/239 (5%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNL----ADKYSELNNQL 60
++ A+VTGAG GIG ++ L G TV + +A L K
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG-GVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+ D+S + E + + ++V+ A I + + + +D + VI VN+
Sbjct: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129
Query: 120 GLIACSRHAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
G ++ A ++ + G +G I+N++SI G Y ASK + T+T
Sbjct: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVG----KVGNVGQTNYAASKAGVIGLTQTAAR 185
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKSAGVGFIDD-AFFCDNSHL-TVKDVSEVILMILS 235
EL I+ SV PG + T + + +D HL +DV++V+ + S
Sbjct: 186 ELG--RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242
>AL645940-11|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 14/239 (5%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNL----ADKYSELNNQL 60
++ A+VTGAG GIG ++ L G TV + +A L K
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG-GVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+ D+S + E + + ++V+ A I + + + +D + VI VN+
Sbjct: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129
Query: 120 GLIACSRHAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
G ++ A ++ + G +G I+N++SI G Y ASK + T+T
Sbjct: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVG----KVGNVGQTNYAASKAGVIGLTQTAAR 185
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKSAGVGFIDD-AFFCDNSHL-TVKDVSEVILMILS 235
EL I+ SV PG + T + + +D HL +DV++V+ + S
Sbjct: 186 ELG--RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 57/239 (23%), Positives = 99/239 (41%), Gaps = 14/239 (5%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNL----ADKYSELNNQL 60
++ A+VTGAG GIG ++ L G TV + +A L K
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNH 69
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYG-GVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+ D+S + E + + ++V+ A I + + + +D + VI VN+
Sbjct: 70 AAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLK 129
Query: 120 GLIACSRHAIDSMKNKG-KGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLRE 178
G ++ A ++ + G +G I+N++SI G Y ASK + T+T
Sbjct: 130 GTFLVTQAAAQALVSNGCRGSIINISSIVG----KVGNVGQTNYAASKAGVIGLTQTAAR 185
Query: 179 ELKMINSKIKITSVSPGIVKTGIFKSAGVGFIDD-AFFCDNSHL-TVKDVSEVILMILS 235
EL I+ SV PG + T + + +D HL +DV++V+ + S
Sbjct: 186 ELG--RHGIRCNSVLPGFIATPMTQKVPQKVVDKITEMIPMGHLGDPEDVADVVAFLAS 242
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 18/200 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
KA +VTG G+G + + L + G TV F + P + + +L + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTV--FAGVLNENGP--GAEELRRTCSPRLSVLQMD 138
Query: 67 ISNDNDLKNAFEGIVKLY--GGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGL 121
I+ +K+A+ + + G+ ++NNA G G + G L D + VN +G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNA--GVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ K KG +VNV+S+ G + Y +SK ++T+F+ +R EL
Sbjct: 197 VEVTKTFLPLLR-KSKGRLVNVSSMGG----GAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 182 MINSKIKITSVSPGIVKTGI 201
IK+ S+ PG T I
Sbjct: 252 KWG--IKVASIQPGGFLTNI 269
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 18/200 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
KA +VTG G+G + + L + G TV F + P + + +L + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTV--FAGVLNENGP--GAEELRRTCSPRLSVLQMD 138
Query: 67 ISNDNDLKNAFEGIVKLY--GGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGL 121
I+ +K+A+ + + G+ ++NNA G G + G L D + VN +G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNA--GVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ K KG +VNV+S+ G + Y +SK ++T+F+ +R EL
Sbjct: 197 VEVTKTFLPLLR-KSKGRLVNVSSMGG----GAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 182 MINSKIKITSVSPGIVKTGI 201
IK+ S+ PG T I
Sbjct: 252 KWG--IKVASIQPGGFLTNI 269
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 18/200 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
KA +VTG G+G + + L + G TV F + P + + +L + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTV--FAGVLNENGP--GAEELRRTCSPRLSVLQMD 138
Query: 67 ISNDNDLKNAFEGIVKLY--GGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGL 121
I+ +K+A+ + + G+ ++NNA G G + G L D + VN +G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNA--GVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ K KG +VNV+S+ G + Y +SK ++T+F+ +R EL
Sbjct: 197 VEVTKTFLPLLR-KSKGRLVNVSSMGG----GAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 182 MINSKIKITSVSPGIVKTGI 201
IK+ S+ PG T I
Sbjct: 252 KWG--IKVASIQPGGFLTNI 269
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 18/200 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
KA +VTG G+G + + L + G TV F + P + + +L + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTV--FAGVLNENGP--GAEELRRTCSPRLSVLQMD 138
Query: 67 ISNDNDLKNAFEGIVKLY--GGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGL 121
I+ +K+A+ + + G+ ++NNA G G + G L D + VN +G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNA--GVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ K KG +VNV+S+ G + Y +SK ++T+F+ +R EL
Sbjct: 197 VEVTKTFLPLLR-KSKGRLVNVSSMGG----GAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 182 MINSKIKITSVSPGIVKTGI 201
IK+ S+ PG T I
Sbjct: 252 KWG--IKVASIQPGGFLTNI 269
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 18/200 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
KA +VTG G+G + + L + G TV F + P + + +L + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTV--FAGVLNENGP--GAEELRRTCSPRLSVLQMD 138
Query: 67 ISNDNDLKNAFEGIVKLY--GGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGL 121
I+ +K+A+ + + G+ ++NNA G G + G L D + VN +G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNA--GVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ K KG +VNV+S+ G + Y +SK ++T+F+ +R EL
Sbjct: 197 VEVTKTFLPLLR-KSKGRLVNVSSMGG----GAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 182 MINSKIKITSVSPGIVKTGI 201
IK+ S+ PG T I
Sbjct: 252 KWG--IKVASIQPGGFLTNI 269
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 50.8 bits (116), Expect = 5e-06
Identities = 53/200 (26%), Positives = 93/200 (46%), Gaps = 18/200 (9%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
KA +VTG G+G + + L + G TV F + P + + +L + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTV--FAGVLNENGP--GAEELRRTCSPRLSVLQMD 138
Query: 67 ISNDNDLKNAFEGIVKLY--GGVDLLVNNAAIGKAGMISTGNL---EDLNNVIDVNIYGL 121
I+ +K+A+ + + G+ ++NNA G G + G L D + VN +G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNA--GVLGFPTDGELLLMTDYKQCMAVNFFGT 196
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELK 181
+ ++ + ++ K KG +VNV+S+ G + Y +SK ++T+F+ +R EL
Sbjct: 197 VEVTKTFLPLLR-KSKGRLVNVSSMGG----GAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 182 MINSKIKITSVSPGIVKTGI 201
IK+ S+ PG T I
Sbjct: 252 KWG--IKVASIQPGGFLTNI 269
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 50.4 bits (115), Expect = 6e-06
Identities = 44/200 (22%), Positives = 83/200 (41%), Gaps = 7/200 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG G+G + + G ++ ++ + +A + + C C S
Sbjct: 44 LITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVRAYTCDC--SQ 101
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ + + K G V +L+NNA I E + DVN + + +
Sbjct: 102 KEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFL 161
Query: 130 DSMKNKGKGHIVNVNSICG-HYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIK 188
+M GH+V ++S G + ++ + + A + +VF +T ++ K IK
Sbjct: 162 PAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK----GIK 217
Query: 189 ITSVSPGIVKTGIFKSAGVG 208
T V P +KTG+F+ G
Sbjct: 218 TTIVCPFFIKTGMFEGCTTG 237
>BC064525-1|AAH64525.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase isoform 1 protein.
Length = 309
Score = 50.0 bits (114), Expect = 8e-06
Identities = 44/200 (22%), Positives = 82/200 (41%), Gaps = 7/200 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG G+G + + G ++ ++ + +A + C C S
Sbjct: 44 LITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDC--SQ 101
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ + + K G V +L+NNA I E + DVN + + +
Sbjct: 102 KEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFL 161
Query: 130 DSMKNKGKGHIVNVNSICG-HYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIK 188
+M GH+V ++S G + ++ + + A + +VF +T ++ K IK
Sbjct: 162 PAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK----GIK 217
Query: 189 ITSVSPGIVKTGIFKSAGVG 208
T V P +KTG+F+ G
Sbjct: 218 TTIVCPFFIKTGMFEGCTTG 237
>BC037219-1|AAH37219.2| 309|Homo sapiens retinal short chain
dehydrogenase reductase isoform 1 protein.
Length = 309
Score = 50.0 bits (114), Expect = 8e-06
Identities = 44/200 (22%), Positives = 82/200 (41%), Gaps = 7/200 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG G+G + + G ++ ++ + +A + C C S
Sbjct: 44 LITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDC--SQ 101
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ + + K G V +L+NNA I E + DVN + + +
Sbjct: 102 KEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFL 161
Query: 130 DSMKNKGKGHIVNVNSICG-HYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIK 188
+M GH+V ++S G + ++ + + A + +VF +T ++ K IK
Sbjct: 162 PAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK----GIK 217
Query: 189 ITSVSPGIVKTGIFKSAGVG 208
T V P +KTG+F+ G
Sbjct: 218 TTIVCPFFIKTGMFEGCTTG 237
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 50.0 bits (114), Expect = 8e-06
Identities = 49/214 (22%), Positives = 93/214 (43%), Gaps = 22/214 (10%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVI----GFEPTQAKLTPLFNLADKYSELNNQLIP 62
K IVTGA GIG Q +L + G +I E +A + + LN+ +
Sbjct: 39 KTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDI-----RGETLNHHVNA 93
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLI 122
D+++ ++ I++ VD+L+NNA + + +T + ++ VN G
Sbjct: 94 RHLDLASLKSIRVFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQ--FGVNHLGHF 151
Query: 123 ACSRHAIDSMKNKGKGHIVNVNS---ICGHY------MPSFSEPVMNVYIASKRSMTVFT 173
+ +D +K I+N++S + GH + Y SK ++ +FT
Sbjct: 152 LLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFT 211
Query: 174 KTLREELKMINSKIKITSVSPGIVKTGIFKSAGV 207
K L L+ S + + ++ PG+ +T + + G+
Sbjct: 212 KELSRRLQ--GSGVTVNALHPGVARTELGRHTGI 243
>AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens
cDNA FLJ13960 fis, clone Y79AA1001233, weakly similar to
ESTRADIOL 17 BETA-DEHYDROGENASE 1 (EC 1.1.1.62). ).
Length = 219
Score = 49.6 bits (113), Expect = 1e-05
Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 6/104 (5%)
Query: 96 IGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFS 155
+G G + +L + NV D N +G + + + MK + +GHIV ++S+ G F+
Sbjct: 1 MGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFN 60
Query: 156 EPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGIVKT 199
+ VY ASK ++ F ++L +L N I I+ V PG V T
Sbjct: 61 D----VYAASKFALEGFFESLAIQLLQFN--IFISLVEPGPVVT 98
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 48.4 bits (110), Expect = 2e-05
Identities = 43/187 (22%), Positives = 83/187 (44%), Gaps = 7/187 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGA G+G ++ + G ++ T+A L + K ++ D+++
Sbjct: 33 LLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGA--PKVFYIAADMAS 90
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
++ + + GG+D LV N G + + ++ VN + + A+
Sbjct: 91 PEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRAL 150
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
S+ + KG +V V+S+ G SFS P Y A+K ++ F +LR EL + + + I
Sbjct: 151 PSLTDS-KGSLVVVSSLLGRVPTSFSTP----YSAAKFALDGFFGSLRRELDVQDVNVAI 205
Query: 190 TSVSPGI 196
T G+
Sbjct: 206 TMCVLGL 212
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 48.4 bits (110), Expect = 2e-05
Identities = 43/187 (22%), Positives = 83/187 (44%), Gaps = 7/187 (3%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGA G+G ++ + G ++ T+A L + K ++ D+++
Sbjct: 33 LLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGA--PKVFYIAADMAS 90
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
++ + + GG+D LV N G + + ++ VN + + A+
Sbjct: 91 PEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRAL 150
Query: 130 DSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKI 189
S+ + KG +V V+S+ G SFS P Y A+K ++ F +LR EL + + + I
Sbjct: 151 PSLTDS-KGSLVVVSSLLGRVPTSFSTP----YSAAKFALDGFFGSLRRELDVQDVNVAI 205
Query: 190 TSVSPGI 196
T G+
Sbjct: 206 TMCVLGL 212
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 47.2 bits (107), Expect = 6e-05
Identities = 45/210 (21%), Positives = 90/210 (42%), Gaps = 15/210 (7%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTV-IGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
K ++TGA GIG + +L G V I + + + N+Q++ K
Sbjct: 40 KVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEI--RVDTKNSQVLVRKL 97
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+S+ ++ EG + + +L+NNA + T + + VN G +
Sbjct: 98 DLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTA--DGFETHLGVNHLGHFLLT 155
Query: 126 RHAIDSMKNKGKGHIVNVNSICGH-----YMPSFSEPVMN---VYIASKRSMTVFTKTLR 177
++ +K +VNV+S+ H + SE + Y SK + +FT+ L
Sbjct: 156 YLLLEQLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELA 215
Query: 178 EELKMINSKIKITSVSPGIVKTGIFKSAGV 207
+ L+ + + +V PG+V++ + + + +
Sbjct: 216 KRLQ--GTGVTTYAVHPGVVRSELVRHSSL 243
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 46.8 bits (106), Expect = 7e-05
Identities = 45/210 (21%), Positives = 90/210 (42%), Gaps = 15/210 (7%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTV-IGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
K ++TGA GIG + +L G V I + + + N+Q++ K
Sbjct: 40 KVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEI--RVDTKNSQVLVRKL 97
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+S+ ++ EG + + +L+NNA + T + + VN G +
Sbjct: 98 DLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTA--DGFETHLGVNHLGHFLLT 155
Query: 126 RHAIDSMKNKGKGHIVNVNSICGH-----YMPSFSEPVMN---VYIASKRSMTVFTKTLR 177
++ +K +VNV+S+ H + SE + Y SK + +FT+ L
Sbjct: 156 YLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELA 215
Query: 178 EELKMINSKIKITSVSPGIVKTGIFKSAGV 207
+ L+ + + +V PG+V++ + + + +
Sbjct: 216 KRLQ--GTGVTTYAVHPGVVRSELVRHSSL 243
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTP---LFNLADKYSELNNQLIPCKCD 66
++TG GIG + L T L L+ A + L + D
Sbjct: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A E + + G VD+LV NA +G G + + + +V+DVN+ G + +
Sbjct: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
+ MK +G G ++ S+ G P +VY ASK ++ ++L
Sbjct: 125 AFLPDMKRRGSGRVLVTGSVGG----LMGLPFNDVYCASKFALEGLCESL 170
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTP---LFNLADKYSELNNQLIPCKCD 66
++TG GIG + L T L L+ A + L + D
Sbjct: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A E + + G VD+LV NA +G G + + + +V+DVN+ G + +
Sbjct: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
+ MK +G G ++ S+ G P +VY ASK ++ ++L
Sbjct: 125 AFLPDMKRRGSGRVLVTGSVGG----LMGLPFNDVYCASKFALEGLCESL 170
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTP---LFNLADKYSELNNQLIPCKCD 66
++TG GIG + L T L L+ A + L + D
Sbjct: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A E + + G VD+LV NA +G G + + + +V+DVN+ G + +
Sbjct: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
+ MK +G G ++ S+ G P +VY ASK ++ ++L
Sbjct: 125 AFLPDMKRRGSGRVLVTGSVGG----LMGLPFNDVYCASKFALEGLCESL 170
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTP---LFNLADKYSELNNQLIPCKCD 66
++TG GIG + L T L L+ A + L + D
Sbjct: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A E + + G VD+LV NA +G G + + + +V+DVN+ G + +
Sbjct: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
+ MK +G G ++ S+ G P +VY ASK ++ ++L
Sbjct: 125 AFLPDMKRRGSGRVLVTGSVGG----LMGLPFNDVYCASKFALEGLCESL 170
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTP---LFNLADKYSELNNQLIPCKCD 66
++TG GIG + L T L L+ A + L + D
Sbjct: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A E + + G VD+LV NA +G G + + + +V+DVN+ G + +
Sbjct: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
+ MK +G G ++ S+ G P +VY ASK ++ ++L
Sbjct: 125 AFLPDMKRRGSGRVLVTGSVGG----LMGLPFNDVYCASKFALEGLCESL 170
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTP---LFNLADKYSELNNQLIPCKCD 66
++TG GIG + L T L L+ A + L + D
Sbjct: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A E + + G VD+LV NA +G G + + + +V+DVN+ G + +
Sbjct: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
+ MK +G G ++ S+ G P +VY ASK ++ ++L
Sbjct: 125 AFLPDMKRRGSGRVLVTGSVGG----LMGLPFNDVYCASKFALEGLCESL 170
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 46.4 bits (105), Expect = 1e-04
Identities = 41/170 (24%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTP---LFNLADKYSELNNQLIPCKCD 66
++TG GIG + L T L L+ A + L + D
Sbjct: 7 LITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLD 66
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSR 126
+ + + A E + + G VD+LV NA +G G + + + +V+DVN+ G + +
Sbjct: 67 VRDSKSVAAARERVTE--GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQ 124
Query: 127 HAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
+ MK +G G ++ S+ G P +VY ASK ++ ++L
Sbjct: 125 AFLPDMKRRGSGRVLVTGSVGG----LMGLPFNDVYCASKFALEGLCESL 170
>Z97054-9|CAI42652.1| 252|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 252
Score = 44.4 bits (100), Expect = 4e-04
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YG 120
G
Sbjct: 123 MG 124
>Z97054-7|CAI42651.1| 169|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 169
Score = 44.4 bits (100), Expect = 4e-04
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YG 120
G
Sbjct: 123 MG 124
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 44.4 bits (100), Expect = 4e-04
Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 5 KNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCK 64
K A++TG G+G E L+ G + + + P + +L N +
Sbjct: 9 KGLVAVITGGASGLGLATAERLVGQGASAVLLD------LPNSGGEAQAKKLGNNCVFAP 62
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLEDLNNVIDVNI 118
D++++ D++ A +G VD+ VN A I A T LED V+DVN+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 119 YG 120
G
Sbjct: 123 MG 124
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 43.6 bits (98), Expect = 7e-04
Identities = 43/163 (26%), Positives = 71/163 (43%), Gaps = 20/163 (12%)
Query: 55 ELNNQLIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMI------STGNLE 108
+L N + D++++ D++ A +G VD+ VN A I A T LE
Sbjct: 3 KLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLE 62
Query: 109 DLNNVIDVNIYGLIACSRHAIDSM----KNKG--KGHIVNVNSICGHYMPSFSEPV-MNV 161
D V+DVN+ G R M ++G +G I+N S+ +F V
Sbjct: 63 DFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVA-----AFEGQVGQAA 117
Query: 162 YIASKRSMTVFTKTLREELKMINSKIKITSVSPGIVKTGIFKS 204
Y ASK + T + +L I I++ +++PG+ T + S
Sbjct: 118 YSASKGGIVGMTLPIARDLAPIG--IRVMTIAPGLFGTPLLTS 158
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 12/202 (5%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIG--FEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+A ++TG G G + + L G TV+ E L L +
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKP 142
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIAC 124
DIS + A L+G V+ +N + A + + + ++VN +G +
Sbjct: 143 GDISRFLEFTKAHTTSTGLWGLVNNAGHNEVVADAEL---SPVATFRSCMEVNFFGALEL 199
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
++ + +++ +G IV V S G MP P + Y SK ++ + T EL +
Sbjct: 200 TKGLLPLLRS-SRGRIVTVGSPAGD-MP---YPCLGAYGTSKAAVALLMDTFSCEL--LP 252
Query: 185 SKIKITSVSPGIVKTGIFKSAG 206
+K++ + PG KT ++ G
Sbjct: 253 WGVKVSIIQPGCFKTESVRNVG 274
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 12/202 (5%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIG--FEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+A ++TG G G + + L G TV+ E L L +
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKP 142
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIAC 124
DIS + A L+G V+ +N + A + + + ++VN +G +
Sbjct: 143 GDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAEL---SPVATFRSCMEVNFFGALEL 199
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
++ + +++ +G IV V S G MP P + Y SK ++ + T EL +
Sbjct: 200 TKGLLPLLRS-SRGRIVTVGSPAGD-MP---YPCLGAYGTSKAAVALLMDTFSCEL--LP 252
Query: 185 SKIKITSVSPGIVKTGIFKSAG 206
+K++ + PG KT ++ G
Sbjct: 253 WGVKVSIIQPGCFKTESVRNVG 274
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase protein.
Length = 214
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 9/129 (6%)
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+ N + L A E + + G VD+LV N +G G + + + +V+DVN+ G +
Sbjct: 66 DVRNSSSLAAARERVTE--GRVDVLVCNTGLGLLGPLGE---DAVASVLDVNVVGTVRVL 120
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ + MK G G ++ S+ G P +VY ASK ++ ++L L
Sbjct: 121 QDFLPDMKRPGSGRVLVTGSMGG----LMGLPFNDVYCASKFALEGLCESLAVLLLPFGV 176
Query: 186 KIKITSVSP 194
+ + P
Sbjct: 177 HVSLIECGP 185
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 12/202 (5%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIG--FEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+A ++TG G G + + L G TV+ E L L +
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKP 142
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIAC 124
DIS + A L+G V+ +N + A + + + ++VN +G +
Sbjct: 143 GDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAEL---SPVATFRSCMEVNFFGALEL 199
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
++ + +++ +G IV V S G MP P + Y SK ++ + T EL +
Sbjct: 200 TKGLLPLLRS-SRGRIVTVGSPAGD-MP---YPCLGAYGTSKAAVALLMDTFSCEL--LP 252
Query: 185 SKIKITSVSPGIVKTGIFKSAG 206
+K++ + PG KT ++ G
Sbjct: 253 WGVKVSIIQPGCFKTESVRNVG 274
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 12/202 (5%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIG--FEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+A ++TG G G + + L G TV+ E L L +
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKP 142
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIAC 124
DIS + A L+G V+ +N + A + + + ++VN +G +
Sbjct: 143 GDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAEL---SPVATFRSCMEVNFFGALEL 199
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
++ + +++ +G IV V S G MP P + Y SK ++ + T EL +
Sbjct: 200 TKGLLPLLRS-SRGRIVTVGSPAGD-MP---YPCLGAYGTSKAAVALLMDTFSCEL--LP 252
Query: 185 SKIKITSVSPGIVKTGIFKSAG 206
+K++ + PG KT ++ G
Sbjct: 253 WGVKVSIIQPGCFKTESVRNVG 274
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/201 (24%), Positives = 86/201 (42%), Gaps = 15/201 (7%)
Query: 9 AIVTGAGQGIGAQITEDLIK--AGMTVI-GFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
A+VTG +GIG I DL + +G V+ + T+ + A+ S +QL
Sbjct: 8 ALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQL----- 62
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
DI + ++ + + K YGG+D+LVNNA I T + N +G
Sbjct: 63 DIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVC 122
Query: 126 RHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMNVYIASKRSMTVFTKTLREEL 180
+ +K +G+ +VNV+SI P + + I + + + K + +
Sbjct: 123 TELLPLIKPQGR--VVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTK 180
Query: 181 KMINSKIKITSVSPGIVKTGI 201
K ++ K S + G+ K G+
Sbjct: 181 KGVHQKEGWPSSAYGVTKIGV 201
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 42.7 bits (96), Expect = 0.001
Identities = 45/202 (22%), Positives = 82/202 (40%), Gaps = 12/202 (5%)
Query: 7 KAAIVTGAGQGIGAQITEDLIKAGMTVIG--FEPTQAKLTPLFNLADKYSELNNQLIPCK 64
+A ++TG G G + + L G TV+ E L L +
Sbjct: 83 RAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRLLQMDLTKP 142
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIAC 124
DIS + A L+G V+ +N + A + + + ++VN +G +
Sbjct: 143 GDISRLLEFTKAHTTSTGLWGLVNNAGHNEVVADAEL---SPVATFRSCMEVNFFGALEL 199
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
++ + +++ +G IV V S G MP P + Y SK ++ + T EL +
Sbjct: 200 TKGLLPLLRS-SRGRIVTVGSPAGD-MP---YPCLGAYGTSKAAVALLMDTFSCEL--LP 252
Query: 185 SKIKITSVSPGIVKTGIFKSAG 206
+K++ + PG KT ++ G
Sbjct: 253 WGVKVSIIQPGCFKTESVRNVG 274
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYS-ELNNQLIP 62
++ K A +TG G G+G +T L G + K+ L A++ S + N++
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCV---IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAA 95
+CD+ + + ++N ++K+ G ++++NNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYS-ELNNQLIP 62
++ K A +TG G G+G +T L G + K+ L A++ S + N++
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCV---IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAA 95
+CD+ + + ++N ++K+ G ++++NNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYS-ELNNQLIP 62
++ K A +TG G G+G +T L G + K+ L A++ S + N++
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCV---IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAA 95
+CD+ + + ++N ++K+ G ++++NNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYS-ELNNQLIP 62
++ K A +TG G G+G +T L G + K+ L A++ S + N++
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCV---IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAA 95
+CD+ + + ++N ++K+ G ++++NNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYS-ELNNQLIP 62
++ K A +TG G G+G +T L G + K+ L A++ S + N++
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCV---IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAA 95
+CD+ + + ++N ++K+ G ++++NNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYS-ELNNQLIP 62
++ K A +TG G G+G +T L G + K+ L A++ S + N++
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCV---IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAA 95
+CD+ + + ++N ++K+ G ++++NNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 4 WKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYS-ELNNQLIP 62
++ K A +TG G G+G +T L G + K+ L A++ S + N++
Sbjct: 57 FQGKVAFITGGGTGLGKGMTTLLSSLGAQCV---IASRKMDVLKATAEQISSQTGNKVHA 113
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAA 95
+CD+ + + ++N ++K+ G ++++NNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retinol
dehydrogenase A2 isoform protein.
Length = 188
Score = 41.5 bits (93), Expect = 0.003
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + G V+ Q + +A E +
Sbjct: 28 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 84
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
C + D + VKL+GG+D+LV+NAA+
Sbjct: 85 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAV 119
>AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol
dehydrogenase short isoform protein.
Length = 174
Score = 41.5 bits (93), Expect = 0.003
Identities = 29/95 (30%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D NK A+VT + GIG I L + G V+ Q + +A E +
Sbjct: 10 DPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQA--VATLQGE-GLSVT 66
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
C + D + VKL+GG+D+LV+NAA+
Sbjct: 67 GTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAV 101
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 41.1 bits (92), Expect = 0.004
Identities = 51/196 (26%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLF-NLADKYSELNNQLIPCKCDI 67
A+V+GA GIG E+L G+ +I + KL + ++AD Y + ++ D
Sbjct: 70 AVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIV---ADF 126
Query: 68 SNDNDLKNAFEGIVKLYGGVDLLVNNAAI-GKAGMISTGNLED-LNNVIDVNIYGLIACS 125
S+ ++ +K V +LVNN + T ED L ++I+VNI
Sbjct: 127 SSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMV 185
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ M + KG IV ++S G P + + ASK + F++ L+ E +
Sbjct: 186 HVVLPGMVERKKGAIVTISS--GSCCK--PTPQLAAFSASKAYLDHFSRALQYE--YASK 239
Query: 186 KIKITSVSPGIVKTGI 201
I + S+ P V T +
Sbjct: 240 GIFVQSLIPFYVATSM 255
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 41.1 bits (92), Expect = 0.004
Identities = 51/196 (26%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLF-NLADKYSELNNQLIPCKCDI 67
A+V+GA GIG E+L G+ +I + KL + ++AD Y + ++ D
Sbjct: 49 AVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIV---ADF 105
Query: 68 SNDNDLKNAFEGIVKLYGGVDLLVNNAAI-GKAGMISTGNLED-LNNVIDVNIYGLIACS 125
S+ ++ +K V +LVNN + T ED L ++I+VNI
Sbjct: 106 SSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMV 164
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ M + KG IV ++S G P + + ASK + F++ L+ E +
Sbjct: 165 HVVLPGMVERKKGAIVTISS--GSCCK--PTPQLAAFSASKAYLDHFSRALQYE--YASK 218
Query: 186 KIKITSVSPGIVKTGI 201
I + S+ P V T +
Sbjct: 219 GIFVQSLIPFYVATSM 234
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 41.1 bits (92), Expect = 0.004
Identities = 51/196 (26%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLF-NLADKYSELNNQLIPCKCDI 67
A+V+GA GIG E+L G+ +I + KL + ++AD Y + ++ D
Sbjct: 70 AVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIV---ADF 126
Query: 68 SNDNDLKNAFEGIVKLYGGVDLLVNNAAI-GKAGMISTGNLED-LNNVIDVNIYGLIACS 125
S+ ++ +K V +LVNN + T ED L ++I+VNI
Sbjct: 127 SSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMV 185
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ M + KG IV ++S G P + + ASK + F++ L+ E +
Sbjct: 186 HVVLPGMVERKKGAIVTISS--GSCCK--PTPQLAAFSASKAYLDHFSRALQYE--YASK 239
Query: 186 KIKITSVSPGIVKTGI 201
I + S+ P V T +
Sbjct: 240 GIFVQSLIPFYVATSM 255
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 41.1 bits (92), Expect = 0.004
Identities = 51/196 (26%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLF-NLADKYSELNNQLIPCKCDI 67
A+V+GA GIG E+L G+ +I + KL + ++AD Y + ++ D
Sbjct: 49 AVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIV---ADF 105
Query: 68 SNDNDLKNAFEGIVKLYGGVDLLVNNAAI-GKAGMISTGNLED-LNNVIDVNIYGLIACS 125
S+ ++ +K V +LVNN + T ED L ++I+VNI
Sbjct: 106 SSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMV 164
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ M + KG IV ++S G P + + ASK + F++ L+ E +
Sbjct: 165 HVVLPGMVERKKGAIVTISS--GSCCK--PTPQLAAFSASKAYLDHFSRALQYE--YASK 218
Query: 186 KIKITSVSPGIVKTGI 201
I + S+ P V T +
Sbjct: 219 GIFVQSLIPFYVATSM 234
>BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 40.7 bits (91), Expect = 0.005
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 85 GGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMKNKGKGHIVNVN 144
GG+D LV N G + + ++ VN + + A+ S+ + KG +V V+
Sbjct: 1 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDS-KGSLVVVS 59
Query: 145 SICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGI 196
S+ G SFS P Y A+K ++ F +LR EL + + + IT G+
Sbjct: 60 SLLGRVPTSFSTP----YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGL 107
>BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 40.7 bits (91), Expect = 0.005
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 85 GGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMKNKGKGHIVNVN 144
GG+D LV N G + + ++ VN + + A+ S+ + KG +V V+
Sbjct: 1 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDS-KGSLVVVS 59
Query: 145 SICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGI 196
S+ G SFS P Y A+K ++ F +LR EL + + + IT G+
Sbjct: 60 SLLGRVPTSFSTP----YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGL 107
>AY313896-1|AAP83168.1| 234|Homo sapiens short-chain
dehydrogenase/reductase 10g protein.
Length = 234
Score = 40.7 bits (91), Expect = 0.005
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 85 GGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMKNKGKGHIVNVN 144
GG+D LV N G + + ++ VN + + A+ S+ + KG +V V+
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDS-KGSLVVVS 83
Query: 145 SICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGI 196
S+ G SFS P Y A+K ++ F +LR EL + + + IT G+
Sbjct: 84 SLLGRVPTSFSTP----YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGL 131
>AY268353-1|AAP42287.1| 199|Homo sapiens short-chain
dehydrogenase/reductase 10c protein.
Length = 199
Score = 40.7 bits (91), Expect = 0.005
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 85 GGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMKNKGKGHIVNVN 144
GG+D LV N G + + ++ VN + + A+ S+ + KG +V V+
Sbjct: 19 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDS-KGSLVVVS 77
Query: 145 SICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGI 196
S+ G SFS P Y A+K ++ F +LR EL + + + IT G+
Sbjct: 78 SLLGRVPTSFSTP----YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGL 125
>AY268351-1|AAP42285.1| 205|Homo sapiens short-chain
dehydrogenase/reductase 10a protein.
Length = 205
Score = 40.7 bits (91), Expect = 0.005
Identities = 32/112 (28%), Positives = 53/112 (47%), Gaps = 5/112 (4%)
Query: 85 GGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAIDSMKNKGKGHIVNVN 144
GG+D LV N G + + ++ VN + + A+ S+ + KG +V V+
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDS-KGSLVVVS 83
Query: 145 SICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKIKITSVSPGI 196
S+ G SFS P Y A+K ++ F +LR EL + + + IT G+
Sbjct: 84 SLLGRVPTSFSTP----YSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGL 131
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 40.3 bits (90), Expect = 0.006
Identities = 50/205 (24%), Positives = 87/205 (42%), Gaps = 19/205 (9%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQL 60
+ H ++K +TG G G + L G+ V+ A LT + +++L
Sbjct: 24 VSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLA-----ACLTDK-GAEQLRGQTSDRL 77
Query: 61 IPCKCDISNDNDLKNAFEGIVKLYGGVDL--LVNNAAI-GKAGMISTGNLEDLNNVIDVN 117
D++ + A + + + G L LVNNA I + N ED N++ VN
Sbjct: 78 ETVTLDVTKMESIAAATQWVKEHVGDRRLWGLVNNAGILTPITLCEWLNTEDSMNMLKVN 137
Query: 118 IYGLIACSRHAIDSMKN-KGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTL 176
+ G+I + + ++ +GK N C + S + Y SK + F+ L
Sbjct: 138 LIGVIQVTLSMLPLVRRARGK------NCQCLQHSGK-SCFLCRGYCVSKYGVEAFSDIL 190
Query: 177 REELKMINSKIKITSVSPGIVKTGI 201
R E++ +KI+ V PG +TG+
Sbjct: 191 RREIQHFG--VKISIVEPGYFRTGM 213
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 40.3 bits (90), Expect = 0.006
Identities = 46/174 (26%), Positives = 77/174 (44%), Gaps = 11/174 (6%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLF-NLADKYSELNNQLIPCKCDI 67
A+V+GA GIG E+L G+ +I + KL + ++AD Y + ++ D
Sbjct: 70 AVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIV---ADF 126
Query: 68 SNDNDLKNAFEGIVKLYGGVDLLVNNAAI-GKAGMISTGNLED-LNNVIDVNIYGLIACS 125
S+ ++ +K V +LVNN + T ED L ++I+VNI
Sbjct: 127 SSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMV 185
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREE 179
+ M + KG IV ++S G P + + ASK + F++ L+ E
Sbjct: 186 HVVLPGMVERKKGAIVTISS--GSCCK--PTPQLAAFSASKAYLDHFSRALQYE 235
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 40.3 bits (90), Expect = 0.006
Identities = 34/161 (21%), Positives = 72/161 (44%), Gaps = 13/161 (8%)
Query: 56 LNNQLIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVID 115
LN+ + D+++ ++ I++ VD+L+NNA + + +T + ++
Sbjct: 16 LNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQ--FG 73
Query: 116 VNIYGLIACSRHAIDSMKNKGKGHIVNVNS---ICGHY------MPSFSEPVMNVYIASK 166
VN G + +D +K I+N++S + GH + Y SK
Sbjct: 74 VNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSK 133
Query: 167 RSMTVFTKTLREELKMINSKIKITSVSPGIVKTGIFKSAGV 207
++ +FTK L L+ S + + ++ PG+ +T + + G+
Sbjct: 134 LAIVLFTKELSRRLQ--GSGVTVNALHPGVARTELGRHTGI 172
>AL023881-1|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 40.3 bits (90), Expect = 0.006
Identities = 47/195 (24%), Positives = 81/195 (41%), Gaps = 22/195 (11%)
Query: 2 DHWKNKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLI 61
D ++K A +TG G GIG +I E ++ G T A+ LA + +
Sbjct: 24 DLLRDKVAFITGGGSGIGFRIAEIFMRHGCH------TAAR-----KLA---GATGRRCL 69
Query: 62 PCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGL 121
P D+ + A + +K +G +D+L+N AA + V+D++ G
Sbjct: 70 PLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGT 129
Query: 122 IACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIAS-KRSMTVFTKTLREEL 180
SR + G IVN+ + G+ + V+ S K ++ T+ L E
Sbjct: 130 FNVSRVLYEKFFRDHGGVIVNITATLGN-----RGQALQVHAGSAKAAVDAMTRHLAVEW 184
Query: 181 KMINSKIKITSVSPG 195
N I++ S++PG
Sbjct: 185 GPQN--IRVNSLAPG 197
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/196 (25%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLF-NLADKYSELNNQLIPCKCDI 67
A+V+GA GIG E+L G+ +I + KL + ++AD Y + ++ D
Sbjct: 70 AVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIV---ADF 126
Query: 68 SNDNDLKNAFEGIVKLYGGVDLLVNNAAI-GKAGMISTGNLED-LNNVIDVNIYGLIACS 125
S+ ++ +K V +LVNN + T ED L ++I+VNI
Sbjct: 127 SSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMV 185
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ M + KG IV ++S G P + + AS+ + F++ L+ E +
Sbjct: 186 HVVLPGMVERKKGAIVTISS--GSCCK--PTPQLAAFSASRAYLDHFSRALQYE--YASK 239
Query: 186 KIKITSVSPGIVKTGI 201
I + S+ P V T +
Sbjct: 240 GIFVQSLIPFYVATSM 255
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 39.9 bits (89), Expect = 0.008
Identities = 50/196 (25%), Positives = 86/196 (43%), Gaps = 13/196 (6%)
Query: 9 AIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLF-NLADKYSELNNQLIPCKCDI 67
A+V+GA GIG E+L G+ +I + KL + ++AD Y + ++ D
Sbjct: 70 AVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIV---ADF 126
Query: 68 SNDNDLKNAFEGIVKLYGGVDLLVNNAAI-GKAGMISTGNLED-LNNVIDVNIYGLIACS 125
S+ ++ +K V +LVNN + T ED L ++I+VNI
Sbjct: 127 SSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMV 185
Query: 126 RHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINS 185
+ M + KG IV ++S G P + + AS+ + F++ L+ E +
Sbjct: 186 HVVLPGMVERKKGAIVTISS--GSCCK--PTPQLAAFSASRAYLDHFSRALQYE--YASK 239
Query: 186 KIKITSVSPGIVKTGI 201
I + S+ P V T +
Sbjct: 240 GIFVQSLIPFYVATSM 255
>BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein.
Length = 305
Score = 39.9 bits (89), Expect = 0.008
Identities = 38/155 (24%), Positives = 68/155 (43%), Gaps = 12/155 (7%)
Query: 57 NNQLIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDV 116
N Q++ K D+S+ ++ +G + + +L+NNA + T + +++ I V
Sbjct: 78 NQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMH--IGV 135
Query: 117 NIYGLIACSRHAIDSMKNKGKGHIVNVNSICG-----HYMPSFSEPVMN---VYIASKRS 168
N G + ++ +K IVNV S+ H+ E N Y SK +
Sbjct: 136 NHLGHFLLTHLLLEKLKESAPSRIVNVFSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLA 195
Query: 169 MTVFTKTLREELKMINSKIKITSVSPGIVKTGIFK 203
+FT+ L LK S + SV PG V++ + +
Sbjct: 196 NILFTQELARRLK--GSGVTTYSVHPGTVQSELVR 228
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 39.9 bits (89), Expect = 0.008
Identities = 36/179 (20%), Positives = 72/179 (40%), Gaps = 3/179 (1%)
Query: 10 IVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKCDISN 69
++TGAG G+G + + G ++ ++ + +A + C C S
Sbjct: 44 LITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDC--SQ 101
Query: 70 DNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACSRHAI 129
+ + + K G V +L+NNA I E + DVN + + +
Sbjct: 102 KEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFL 161
Query: 130 DSMKNKGKGHIVNVNSICG-HYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMINSKI 187
+M GH+V ++S G + ++ + + A + +VF +T ++ K I + I
Sbjct: 162 PAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTI 220
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 39.9 bits (89), Expect = 0.008
Identities = 29/102 (28%), Positives = 55/102 (53%), Gaps = 10/102 (9%)
Query: 106 NLEDLNNVI----DVNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNV 161
++ DL+NVI ++NI + ++ + M + KG I+N++S G +P P++ +
Sbjct: 11 DVPDLDNVIKKMININILSVCKMTQLVLPGMVERSKGAILNISSGSG-MLP---VPLLTI 66
Query: 162 YIASKRSMTVFTKTLREELKMINSKIKITSVSPGIVKTGIFK 203
Y A+K + F++ L EE + + + + SV P V T + K
Sbjct: 67 YSATKTFVDFFSQCLHEEYR--SKGVFVQSVLPYFVATKLAK 106
>AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 147
Score = 39.1 bits (87), Expect = 0.015
Identities = 34/143 (23%), Positives = 61/143 (42%), Gaps = 5/143 (3%)
Query: 65 CDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIAC 124
CD+ N ++ + + + G + +LVNNAA+ + + + L +N G
Sbjct: 10 CDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWT 69
Query: 125 SRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFTKTLREELKMIN 184
++ + M GHIV +NS+ + + P Y SK S F ++L L +
Sbjct: 70 TKAFLPRMLELQNGHIVCLNSV----LALSAIPGAIDYCTSKASAFAFMESLTLGL-LDC 124
Query: 185 SKIKITSVSPGIVKTGIFKSAGV 207
+ T+V P T +F+ V
Sbjct: 125 PGVSATTVLPFHTSTEMFQGMRV 147
>BC004331-1|AAH04331.1| 345|Homo sapiens HSDL2 protein protein.
Length = 345
Score = 38.7 bits (86), Expect = 0.020
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 10/131 (7%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVI----GFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+TGA +GIG I K G ++ +P L ++ A++ + + +PC D
Sbjct: 15 ITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVD 74
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVN-IYGLIACS 125
+ ++ + A E +K +G + A G + M G E+ I VN ++ A
Sbjct: 75 VRDEQQISAAVEKAIKKFGAYTI----AKYGMS-MYVLGMAEEFKGEIAVNALWPKTAIH 129
Query: 126 RHAIDSMKNKG 136
A+D + G
Sbjct: 130 TAAMDMLGGPG 140
>AL162732-1|CAM17151.1| 345|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 345
Score = 38.7 bits (86), Expect = 0.020
Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 10/131 (7%)
Query: 11 VTGAGQGIGAQITEDLIKAGMTVI----GFEPTQAKLTPLFNLADKYSELNNQLIPCKCD 66
+TGA +GIG I K G ++ +P L ++ A++ + + +PC D
Sbjct: 15 ITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVD 74
Query: 67 ISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVN-IYGLIACS 125
+ ++ + A E +K +G + A G + M G E+ I VN ++ A
Sbjct: 75 VRDEQQISAAVEKAIKKFGAYTI----AKYGMS-MYVLGMAEEFKGEIAVNALWPKTAIH 129
Query: 126 RHAIDSMKNKG 136
A+D + G
Sbjct: 130 TAAMDMLGGPG 140
>CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 38.3 bits (85), Expect = 0.026
Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 6/149 (4%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
++ AIVTG GIG + L + GM VI +K + + K LN+++ C
Sbjct: 120 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKI-KEETLNDKVEFLYC 178
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+++ ++ + + +L+NNA + T + +N G +
Sbjct: 179 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKT--RDGFEEHFGLNYLGHFLLT 236
Query: 126 RHAIDSMKNKGK-GHIVNVNSICG--HYM 151
+D++K G GH V ++ HY+
Sbjct: 237 NLLLDTLKESGSPGHSARVVTVSSATHYV 265
>BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 38.3 bits (85), Expect = 0.026
Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 6/149 (4%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIKAGMTVIGFEPTQAKLTPLFNLADKYSELNNQLIPCKC 65
++ AIVTG GIG + L + GM VI +K + + K LN+++ C
Sbjct: 120 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKI-KEETLNDKVEFLYC 178
Query: 66 DISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIYGLIACS 125
D+++ ++ + + +L+NNA + T + +N G +
Sbjct: 179 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKT--RDGFEEHFGLNYLGHFLLT 236
Query: 126 RHAIDSMKNKGK-GHIVNVNSICG--HYM 151
+D++K G GH V ++ HY+
Sbjct: 237 NLLLDTLKESGSPGHSARVVTVSSATHYV 265
>EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein.
Length = 377
Score = 36.3 bits (80), Expect = 0.10
Identities = 33/146 (22%), Positives = 61/146 (41%), Gaps = 7/146 (4%)
Query: 1 MDHWKNKAAIVTGAGQGIGAQITEDLIKAG-MTVIGFEPTQAKLTPLFNLADKYSELNNQ 59
M + + + A+VTGA GIG +L + G V+ + F+L + NN+
Sbjct: 31 MGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESG--NNE 88
Query: 60 LIPCKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAIGKAGMISTGNLEDLNNVIDVNIY 119
+I D+++ ++ + +D+L++NA I G E N ++ VN
Sbjct: 89 VIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGR----TREAFNLLLRVNHI 144
Query: 120 GLIACSRHAIDSMKNKGKGHIVNVNS 145
G + + +K +V V S
Sbjct: 145 GPFLLTHLLLPCLKACAPSRVVVVAS 170
>AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase
(NADPH) 3, EC 1.1.1.284. protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3
variant protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbonyl
reductase 3 protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 36.3 bits (80), Expect = 0.10
Identities = 29/94 (30%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 6 NKAAIVTGAGQGIGAQITEDLIK--AGMTVIGFEPTQAKLTPLFNL-ADKYSELNNQLIP 62
++ A+VTGA +GIG I +L + +G V+ + L A+ S +QL
Sbjct: 5 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQL-- 62
Query: 63 CKCDISNDNDLKNAFEGIVKLYGGVDLLVNNAAI 96
DI + ++ + + K YGG+++LVNNAA+
Sbjct: 63 ---DIDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>BC072434-1|AAH72434.1| 152|Homo sapiens HSD11B1L protein protein.
Length = 152
Score = 35.5 bits (78), Expect = 0.18
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 5/83 (6%)
Query: 114 IDVNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFT 173
+ VN + + A+ S+ + KG +V V+S+ G SFS P Y A+K ++ F
Sbjct: 1 MQVNFVSYVQLTSRALPSLTDS-KGSLVVVSSLLGRVPTSFSTP----YSAAKFALDGFF 55
Query: 174 KTLREELKMINSKIKITSVSPGI 196
+LR EL + + + IT G+
Sbjct: 56 GSLRRELDVQDVNVAITMCVLGL 78
>BC053546-1|AAH53546.1| 152|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1-like protein.
Length = 152
Score = 35.5 bits (78), Expect = 0.18
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 5/83 (6%)
Query: 114 IDVNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFT 173
+ VN + + A+ S+ + KG +V V+S+ G SFS P Y A+K ++ F
Sbjct: 1 MQVNFVSYVQLTSRALPSLTDS-KGSLVVVSSLLGRVPTSFSTP----YSAAKFALDGFF 55
Query: 174 KTLREELKMINSKIKITSVSPGI 196
+LR EL + + + IT G+
Sbjct: 56 GSLRRELDVQDVNVAITMCVLGL 78
>AY313895-1|AAP83167.1| 181|Homo sapiens short-chain
dehydrogenase/reductase 10f protein.
Length = 181
Score = 35.5 bits (78), Expect = 0.18
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 5/83 (6%)
Query: 114 IDVNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFT 173
+ VN + + A+ S+ + KG +V V+S+ G SFS P Y A+K ++ F
Sbjct: 1 MQVNFVSYVQLTSRALPSLTDS-KGSLVVVSSLLGRVPTSFSTP----YSAAKFALDGFF 55
Query: 174 KTLREELKMINSKIKITSVSPGI 196
+LR EL + + + IT G+
Sbjct: 56 GSLRRELDVQDVNVAITMCVLGL 78
>AY268354-1|AAP42288.1| 152|Homo sapiens short-chain
dehydrogenase/reductase 10d protein.
Length = 152
Score = 35.5 bits (78), Expect = 0.18
Identities = 25/83 (30%), Positives = 42/83 (50%), Gaps = 5/83 (6%)
Query: 114 IDVNIYGLIACSRHAIDSMKNKGKGHIVNVNSICGHYMPSFSEPVMNVYIASKRSMTVFT 173
+ VN + + A+ S+ + KG +V V+S+ G SFS P Y A+K ++ F
Sbjct: 1 MQVNFVSYVQLTSRALPSLTDS-KGSLVVVSSLLGRVPTSFSTP----YSAAKFALDGFF 55
Query: 174 KTLREELKMINSKIKITSVSPGI 196
+LR EL + + + IT G+
Sbjct: 56 GSLRRELDVQDVNVAITMCVLGL 78
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.136 0.392
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 33,944,559
Number of Sequences: 224733
Number of extensions: 1275937
Number of successful extensions: 3301
Number of sequences better than 10.0: 265
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 138
Number of HSP's that attempted gapping in prelim test: 2939
Number of HSP's gapped (non-prelim): 287
length of query: 254
length of database: 73,234,838
effective HSP length: 88
effective length of query: 166
effective length of database: 53,458,334
effective search space: 8874083444
effective search space used: 8874083444
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 64 (29.9 bits)
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