Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005245-TA|BGIBMGA005245-PA|IPR000595|Cyclic
nucleotide-binding
(149 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 67 3e-11
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 67 3e-11
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 67 3e-11
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 67 3e-11
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 66 5e-11
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 66 5e-11
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 65 8e-11
AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization activ... 63 3e-10
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 61 1e-09
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 61 1e-09
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 61 1e-09
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 61 1e-09
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 61 1e-09
BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated... 56 4e-08
BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated... 56 4e-08
BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated... 56 4e-08
AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein. 56 4e-08
AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor cGMP... 56 4e-08
AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein. 56 4e-08
S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-ga... 51 2e-06
AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein. 51 2e-06
BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated... 50 4e-06
BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated... 50 4e-06
S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein. 49 7e-06
M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel... 49 7e-06
M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein ki... 45 9e-05
BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase, cAMP-de... 45 9e-05
BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein. 45 9e-05
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 45 1e-04
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 45 1e-04
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 45 1e-04
U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel... 45 1e-04
S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein. 45 1e-04
L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated c... 45 1e-04
L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated c... 45 1e-04
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 45 1e-04
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 45 1e-04
BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein. 45 1e-04
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 45 1e-04
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 45 1e-04
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 45 1e-04
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 45 1e-04
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 45 1e-04
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 45 1e-04
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 45 1e-04
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 45 1e-04
AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor CNG-c... 45 1e-04
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 44 3e-04
BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein. 44 3e-04
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 44 3e-04
AB209681-1|BAD92918.1| 643|Homo sapiens RAP guanine-nucleotide-... 44 3e-04
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 44 3e-04
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 43 5e-04
BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein. 43 5e-04
BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein. 43 5e-04
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 43 5e-04
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 43 5e-04
U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine nu... 42 6e-04
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 42 6e-04
AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cycl... 42 6e-04
M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein ki... 42 9e-04
M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein ki... 42 9e-04
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 42 9e-04
BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase, cAMP-de... 42 9e-04
BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase, cAMP-de... 42 9e-04
AF032897-1|AAD01946.1| 1196|Homo sapiens potassium channel subun... 42 9e-04
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 41 0.002
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 41 0.002
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 41 0.002
S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein. 40 0.003
AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase, cGMP-de... 40 0.003
AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase, cGMP-de... 40 0.003
AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens ... 39 0.006
AK090969-1|BAC03559.1| 430|Homo sapiens protein ( Homo sapiens ... 39 0.006
AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member... 39 0.006
BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholip... 38 0.010
BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholip... 38 0.010
BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein. 38 0.010
AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target ester... 38 0.010
AC007740-1|AAX93153.1| 940|Homo sapiens unknown protein. 38 0.018
U04270-1|AAA62473.1| 1159|Homo sapiens putative potassium channe... 37 0.032
DQ784808-1|ABQ01243.1| 1159|Homo sapiens potassium voltage-gated... 37 0.032
DQ525913-1|ABF71886.1| 1159|Homo sapiens voltage-gated potassium... 37 0.032
BC004311-1|AAH04311.2| 444|Homo sapiens KCNH2 protein protein. 37 0.032
AJ512214-1|CAD54447.1| 819|Homo sapiens potassium channel 1b pr... 37 0.032
AJ010538-1|CAA09232.1| 1133|Homo sapiens ether-a-go-go-related p... 37 0.032
AF363636-1|AAL37559.1| 1159|Homo sapiens ether-a-go-go-related K... 37 0.032
AB009071-1|BAA37096.1| 1159|Homo sapiens HERG protein. 37 0.032
BC114945-1|AAI14946.1| 423|Homo sapiens C20orf152 protein protein. 34 0.23
AL359828-2|CAI23442.1| 572|Homo sapiens chromosome 20 open read... 34 0.23
AL359828-1|CAI23441.1| 576|Homo sapiens chromosome 20 open read... 34 0.23
AL109965-6|CAI19249.1| 572|Homo sapiens chromosome 20 open read... 34 0.23
AL109965-5|CAI19248.1| 576|Homo sapiens chromosome 20 open read... 34 0.23
AK057454-1|BAB71494.1| 572|Homo sapiens protein ( Homo sapiens ... 34 0.23
AL365502-7|CAI14582.1| 1317|Homo sapiens patatin-like phospholip... 33 0.39
AL365502-6|CAI14581.1| 1281|Homo sapiens patatin-like phospholip... 33 0.39
AL365502-5|CAI14579.1| 923|Homo sapiens patatin-like phospholip... 33 0.39
AK125060-1|BAC86036.1| 1317|Homo sapiens protein ( Homo sapiens ... 33 0.39
AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor cGMP... 33 0.52
Z84814-4|CAC69895.2| 243|Homo sapiens butyrophilin-like 2 (MHC ... 30 3.7
BX255945-4|CAI18727.2| 259|Homo sapiens butyrophilin-like 2 (MH... 30 3.7
AL935032-3|CAI18475.2| 259|Homo sapiens butyrophilin-like 2 (MH... 30 3.7
AL670296-4|CAI17570.2| 259|Homo sapiens butyrophilin-like 2 (MH... 30 3.7
AL662796-4|CAI18265.2| 259|Homo sapiens butyrophilin-like 2 (MH... 30 3.7
AL034394-4|CAI42180.1| 243|Homo sapiens butyrophilin-like 2 (MH... 30 3.7
AF186593-1|AAF05530.1| 455|Homo sapiens butyrophilin-like protein. 30 3.7
BC042592-1|AAH42592.1| 1124|Homo sapiens solute carrier family 9... 29 6.4
AY881999-2|AAX35330.1| 270|Homo sapiens butyrophyllin-like prot... 29 6.4
AY881999-1|AAX35331.1| 388|Homo sapiens butyrophyllin-like prot... 29 6.4
AL139142-3|CAI20938.1| 1124|Homo sapiens solute carrier family 9... 29 6.4
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 66.9 bits (156), Expect = 3e-11
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
R+LV + + + KL +F GD I + ++G +YFI G V++ ++
Sbjct: 536 RKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKG 595
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKK 124
KE+ L DG +FG I L+ R R + A T C L+ LS ++F + YP + + +
Sbjct: 596 NKEM-KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFET 654
Query: 125 RAINRYE 131
AI+R +
Sbjct: 655 VAIDRLD 661
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 66.9 bits (156), Expect = 3e-11
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
R+LV + + + KL +F GD I + ++G +YFI G V++ ++
Sbjct: 536 RKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKG 595
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKK 124
KE+ L DG +FG I L+ R R + A T C L+ LS ++F + YP + + +
Sbjct: 596 NKEM-KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFET 654
Query: 125 RAINRYE 131
AI+R +
Sbjct: 655 VAIDRLD 661
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 66.9 bits (156), Expect = 3e-11
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
R+LV + + + KL +F GD I + ++G +YFI G V++ ++
Sbjct: 536 RKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKG 595
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKK 124
KE+ L DG +FG I L+ R R + A T C L+ LS ++F + YP + + +
Sbjct: 596 NKEM-KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFET 654
Query: 125 RAINRYE 131
AI+R +
Sbjct: 655 VAIDRLD 661
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 66.9 bits (156), Expect = 3e-11
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 1/127 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
R+LV + + + KL +F GD I + ++G +YFI G V++ ++
Sbjct: 390 RKLVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKG 449
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKK 124
KE+ L DG +FG I L+ R R + A T C L+ LS ++F + YP + + +
Sbjct: 450 NKEM-KLSDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFET 508
Query: 125 RAINRYE 131
AI+R +
Sbjct: 509 VAIDRLD 515
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 66.1 bits (154), Expect = 5e-11
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
R+LV + + + KL +F GD I + ++G +YFI G V++ ++
Sbjct: 587 RKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKG 646
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKK 124
KE L DG +FG I L+ R R + A T C L+ LS ++F + YP + + +
Sbjct: 647 NKET-KLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFET 705
Query: 125 RAINRYE 131
A++R +
Sbjct: 706 VALDRLD 712
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 66.1 bits (154), Expect = 5e-11
Identities = 37/127 (29%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
R+LV + + + KL +F GD I + ++G +YFI G V++ ++
Sbjct: 587 RKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKG 646
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKK 124
KE L DG +FG I L+ R R + A T C L+ LS ++F + YP + + +
Sbjct: 647 NKET-KLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFET 705
Query: 125 RAINRYE 131
A++R +
Sbjct: 706 VALDRLD 712
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 65.3 bits (152), Expect = 8e-11
Identities = 35/104 (33%), Positives = 56/104 (53%), Gaps = 1/104 (0%)
Query: 28 KLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRF 87
KL +F GD I + +VG +YFI G + ++S KE+ L DG +FG I L+ +
Sbjct: 369 KLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGR 427
Query: 88 RLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKKRAINRYE 131
R + A T C L+ LS ++F + YP + + + AI+R +
Sbjct: 428 RTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAIDRLD 471
>AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 890
Score = 63.3 bits (147), Expect = 3e-10
Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 1/104 (0%)
Query: 28 KLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRF 87
KL +F GD I + +VG +YFI G + ++S KE+ L DG +FG I L+ +
Sbjct: 490 KLRFEVFQPGDYIVREGAVGKKMYFIQHGVAGVITKSSKEM-KLTDGSYFGEICLLTKGR 548
Query: 88 RLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKKRAINRYE 131
R + A T C L+ LS ++F YP + + + AI+R +
Sbjct: 549 RTASVRADTYCRLYSLSVDNFNEVPEEYPMMRRAFETVAIDRLD 592
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 61.3 bits (142), Expect = 1e-09
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 1/127 (0%)
Query: 3 TGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS 62
T R LV + + + KL +F GD++ + SVG +YFI G +++ +
Sbjct: 94 TCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLA 153
Query: 63 ESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESI 122
++ L DG +FG I L+ R R + A T C L+ LS + F + + +P + +
Sbjct: 154 RGARDT-RLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAF 212
Query: 123 KKRAINR 129
+ A++R
Sbjct: 213 ETVAMDR 219
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 61.3 bits (142), Expect = 1e-09
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 1/127 (0%)
Query: 3 TGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS 62
T R LV + + + KL +F GD++ + SVG +YFI G +++ +
Sbjct: 215 TCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLA 274
Query: 63 ESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESI 122
++ L DG +FG I L+ R R + A T C L+ LS + F + + +P + +
Sbjct: 275 RGARDT-RLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAF 333
Query: 123 KKRAINR 129
+ A++R
Sbjct: 334 ETVAMDR 340
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 61.3 bits (142), Expect = 1e-09
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 1/127 (0%)
Query: 3 TGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS 62
T R LV + + + KL +F GD++ + SVG +YFI G +++ +
Sbjct: 418 TCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLA 477
Query: 63 ESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESI 122
++ L DG +FG I L+ R R + A T C L+ LS + F + + +P + +
Sbjct: 478 RGARDT-RLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAF 536
Query: 123 KKRAINR 129
+ A++R
Sbjct: 537 ETVAMDR 543
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 61.3 bits (142), Expect = 1e-09
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 1/127 (0%)
Query: 3 TGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS 62
T R LV + + + KL +F GD++ + SVG +YFI G +++ +
Sbjct: 418 TCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLA 477
Query: 63 ESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESI 122
++ L DG +FG I L+ R R + A T C L+ LS + F + + +P + +
Sbjct: 478 RGARDT-RLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAF 536
Query: 123 KKRAINR 129
+ A++R
Sbjct: 537 ETVAMDR 543
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 61.3 bits (142), Expect = 1e-09
Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 1/127 (0%)
Query: 3 TGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS 62
T R LV + + + KL +F GD++ + SVG +YFI G +++ +
Sbjct: 355 TCRGLVAHMPLFAHADPSFVTAVLTKLRFEVFQPGDLVVREGSVGRKMYFIQHGLLSVLA 414
Query: 63 ESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESI 122
++ L DG +FG I L+ R R + A T C L+ LS + F + + +P + +
Sbjct: 415 RGARDT-RLTDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNAVLEEFPMMRRAF 473
Query: 123 KKRAINR 129
+ A++R
Sbjct: 474 ETVAMDR 480
>BC096300-1|AAH96300.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 56.4 bits (130), Expect = 4e-08
Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V + LLV++ KL +F GD I K +G +Y I++G +A+ ++ G
Sbjct: 477 LKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVT 536
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG +FG IS++ R ++ +LF LSK+D + YP +
Sbjct: 537 QFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAKK 596
Query: 121 SIKKRAINRYEETCVLDE 138
+++++ + ++DE
Sbjct: 597 ALEEKGRQILMKDNLIDE 614
>BC096299-1|AAH96299.1| 676|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 676
Score = 56.4 bits (130), Expect = 4e-08
Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V + LLV++ KL +F GD I K +G +Y I++G +A+ ++ G
Sbjct: 459 LKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVT 518
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG +FG IS++ R ++ +LF LSK+D + YP +
Sbjct: 519 QFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAKK 578
Query: 121 SIKKRAINRYEETCVLDE 138
+++++ + ++DE
Sbjct: 579 ALEEKGRQILMKDNLIDE 596
>BC096298-1|AAH96298.1| 694|Homo sapiens cyclic nucleotide gated
channel alpha 3 protein.
Length = 694
Score = 56.4 bits (130), Expect = 4e-08
Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V + LLV++ KL +F GD I K +G +Y I++G +A+ ++ G
Sbjct: 477 LKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVT 536
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG +FG IS++ R ++ +LF LSK+D + YP +
Sbjct: 537 QFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAKK 596
Query: 121 SIKKRAINRYEETCVLDE 138
+++++ + ++DE
Sbjct: 597 ALEEKGRQILMKDNLIDE 614
>AK131300-1|BAD18468.1| 698|Homo sapiens mRNA. protein.
Length = 698
Score = 56.4 bits (130), Expect = 4e-08
Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V + LLV++ KL +F GD I K +G +Y I++G +A+ ++ G
Sbjct: 481 LKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVT 540
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG +FG IS++ R ++ +LF LSK+D + YP +
Sbjct: 541 QFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAKK 600
Query: 121 SIKKRAINRYEETCVLDE 138
+++++ + ++DE
Sbjct: 601 ALEEKGRQILMKDNLIDE 618
>AF065314-1|AAC17440.1| 694|Homo sapiens cone photoreceptor
cGMP-gated channel alpha subunit protein.
Length = 694
Score = 56.4 bits (130), Expect = 4e-08
Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V + LLV++ KL +F GD I K +G +Y I++G +A+ ++ G
Sbjct: 477 LKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVT 536
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG +FG IS++ R ++ +LF LSK+D + YP +
Sbjct: 537 QFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAKK 596
Query: 121 SIKKRAINRYEETCVLDE 138
+++++ + ++DE
Sbjct: 597 ALEEKGRQILMKDNLIDE 614
>AC092675-2|AAY24181.1| 694|Homo sapiens unknown protein.
Length = 694
Score = 56.4 bits (130), Expect = 4e-08
Identities = 35/138 (25%), Positives = 68/138 (49%), Gaps = 7/138 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V + LLV++ KL +F GD I K +G +Y I++G +A+ ++ G
Sbjct: 477 LKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVT 536
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG +FG IS++ R ++ +LF LSK+D + YP +
Sbjct: 537 QFVVLSDGSYFGEISILNIKGSKSGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPEAKK 596
Query: 121 SIKKRAINRYEETCVLDE 138
+++++ + ++DE
Sbjct: 597 ALEEKGRQILMKDNLIDE 614
>S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-gated
channel protein.
Length = 686
Score = 50.8 bits (116), Expect = 2e-06
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 7/125 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V LLV++ KL ++ GD I K +G +Y I +G +A+ ++ G
Sbjct: 470 LKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVT 529
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG +FG IS++ R ++ +LF LSK+D + YP
Sbjct: 530 QFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKT 589
Query: 121 SIKKR 125
++++
Sbjct: 590 MLEEK 594
>AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein.
Length = 690
Score = 50.8 bits (116), Expect = 2e-06
Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 7/125 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V LLV++ KL ++ GD I K +G +Y I +G +A+ ++ G
Sbjct: 474 LKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVT 533
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG +FG IS++ R ++ +LF LSK+D + YP
Sbjct: 534 QFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKT 593
Query: 121 SIKKR 125
++++
Sbjct: 594 MLEEK 598
>BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 49.6 bits (113), Expect = 4e-06
Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V LLV++ KL +F GD I + +G +Y I +G +A+ ++ G
Sbjct: 449 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVT 508
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L G FG IS++ + R ++ +LF LSK+D + YP +
Sbjct: 509 QYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKK 568
Query: 121 SIKKRAINRYEETCVLDEH 139
+++R + +LDE+
Sbjct: 569 VLEERGREILMKEGLLDEN 587
>BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 49.6 bits (113), Expect = 4e-06
Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V LLV++ KL +F GD I + +G +Y I +G +A+ ++ G
Sbjct: 449 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVT 508
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L G FG IS++ + R ++ +LF LSK+D + YP +
Sbjct: 509 QYALLSAGSCFGEISILNIKGSKMGNRRTANIRSLGYSDLFCLSKDDLMEAVTEYPDAKK 568
Query: 121 SIKKRAINRYEETCVLDEH 139
+++R + +LDE+
Sbjct: 569 VLEERGREILMKEGLLDEN 587
>S76069-1|AAD14208.1| 261|Homo sapiens CNG3 protein.
Length = 261
Score = 48.8 bits (111), Expect = 7e-06
Identities = 24/77 (31%), Positives = 43/77 (55%), Gaps = 1/77 (1%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V + LLV++ KL +F GD I K +G +Y I++G +A+ ++ G
Sbjct: 158 LKKVRIFQDCEAGLLVELVLKLRPTVFSPGDYICKKGDIGKEMYIINEGKLAVVADDGVT 217
Query: 67 EVCHLEDGDFFGAISLI 83
+ L DG +FG IS++
Sbjct: 218 QFVVLSDGSYFGEISIL 234
>M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel
protein protein.
Length = 690
Score = 48.8 bits (111), Expect = 7e-06
Identities = 32/125 (25%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V LLV++ KL ++ GD I K +G +Y I +G +A+ ++ G
Sbjct: 474 LKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVT 533
Query: 67 EVCHLEDGDFFGAISLI------LRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+ L DG FG IS++ R ++ +LF LSK+D + YP
Sbjct: 534 QFVVLSDGSTFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKT 593
Query: 121 SIKKR 125
++++
Sbjct: 594 MLEEK 598
>M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein
kinase RI-beta regulatory subunit protein.
Length = 380
Score = 45.2 bits (102), Expect = 9e-05
Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 32 VIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTT 91
V IAG+ + + + GD Y +D+G V +Y +G+ V ++ +G FG ++LI R T
Sbjct: 155 VTHIAGETVIQQGNEGDNFYVVDQGEVDVY-VNGEWVTNISEGGSFGELALIYGTPRAAT 213
Query: 92 AVAVTNCELFRLSKEDF 108
A T+ +L+ + ++ +
Sbjct: 214 VKAKTDLKLWGIDRDSY 230
Score = 43.2 bits (97), Expect = 4e-04
Identities = 38/130 (29%), Positives = 58/130 (44%), Gaps = 9/130 (6%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIY---- 61
+ + +V L+ L + + + +L V F G+ I GD Y I +GT ++
Sbjct: 247 EFLSKVSILESLEKWERLTVADRLEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRS 306
Query: 62 -SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+E EV L D+FG I+L+L R R T VA + +L + F + P
Sbjct: 307 PNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLG--PC--S 362
Query: 121 SIKKRAINRY 130
I KR I RY
Sbjct: 363 EILKRNIQRY 372
>BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, beta protein.
Length = 381
Score = 45.2 bits (102), Expect = 9e-05
Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 32 VIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTT 91
V IAG+ + + + GD Y +D+G V +Y +G+ V ++ +G FG ++LI R T
Sbjct: 156 VTHIAGETVIQQGNEGDNFYVVDQGEVDVY-VNGEWVTNISEGGSFGELALIYGTPRAAT 214
Query: 92 AVAVTNCELFRLSKEDF 108
A T+ +L+ + ++ +
Sbjct: 215 VKAKTDLKLWGIDRDSY 231
Score = 41.9 bits (94), Expect = 9e-04
Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 9/130 (6%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIY---- 61
+ + +V L+ L + + + L V F G+ I GD Y I +GT ++
Sbjct: 248 EFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRS 307
Query: 62 -SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+E EV L D+FG I+L+L R R T VA + +L + F + P
Sbjct: 308 PNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLG--PC--S 363
Query: 121 SIKKRAINRY 130
I KR I RY
Sbjct: 364 EILKRNIQRY 373
>BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein.
Length = 381
Score = 45.2 bits (102), Expect = 9e-05
Identities = 23/77 (29%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 32 VIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTT 91
V IAG+ + + + GD Y +D+G V +Y +G+ V ++ +G FG ++LI R T
Sbjct: 156 VTHIAGETVIQQGNEGDNFYVVDQGEVDVY-VNGEWVTNISEGGSFGELALIYGTPRAAT 214
Query: 92 AVAVTNCELFRLSKEDF 108
A T+ +L+ + ++ +
Sbjct: 215 VKAKTDLKLWGIDRDSY 231
Score = 41.9 bits (94), Expect = 9e-04
Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 9/130 (6%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIY---- 61
+ + +V L+ L + + + L V F G+ I GD Y I +GT ++
Sbjct: 248 EFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRS 307
Query: 62 -SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYE 120
+E EV L D+FG I+L+L R R T VA + +L + F + P
Sbjct: 308 PNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLG--PC--S 363
Query: 121 SIKKRAINRY 130
I KR I RY
Sbjct: 364 EILKRNIQRY 373
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 110 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 168
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 169 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 336
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 95 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 153
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 154 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 201
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 214 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 273
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 274 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 321
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 110 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 168
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 169 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 336
>U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel beta
subunit protein.
Length = 1251
Score = 44.8 bits (101), Expect = 1e-04
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 9/127 (7%)
Query: 7 LVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS-ESG 65
+V +V + R ++ + +L V+++ D + K +G +Y I G V + G
Sbjct: 956 IVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDG 1015
Query: 66 KEVC-HLEDGDFFGAISLIL-----RRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVY 119
K V L+ G FG ISL+ RR A TN LF L K+D + YP
Sbjct: 1016 KSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTN--LFILDKKDLNEILVHYPESQ 1073
Query: 120 ESIKKRA 126
+ ++K+A
Sbjct: 1074 KLLRKKA 1080
>S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein.
Length = 261
Score = 44.8 bits (101), Expect = 1e-04
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 1/77 (1%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V LLV++ KL ++ GD I K +G +Y I +G +A+ ++ G
Sbjct: 158 LKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVT 217
Query: 67 EVCHLEDGDFFGAISLI 83
+ L DG +FG IS++
Sbjct: 218 QFVVLSDGSYFGEISIL 234
>L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 623
Score = 44.8 bits (101), Expect = 1e-04
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 9/127 (7%)
Query: 7 LVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS-ESG 65
+V +V + R ++ + +L V+++ D + K +G +Y I G V + G
Sbjct: 328 IVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDG 387
Query: 66 KEVC-HLEDGDFFGAISLIL-----RRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVY 119
K V L+ G FG ISL+ RR A TN LF L K+D + YP
Sbjct: 388 KSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTN--LFILDKKDLNEILVHYPESQ 445
Query: 120 ESIKKRA 126
+ ++K+A
Sbjct: 446 KLLRKKA 452
>L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 909
Score = 44.8 bits (101), Expect = 1e-04
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 9/127 (7%)
Query: 7 LVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS-ESG 65
+V +V + R ++ + +L V+++ D + K +G +Y I G V + G
Sbjct: 614 IVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDG 673
Query: 66 KEVC-HLEDGDFFGAISLIL-----RRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVY 119
K V L+ G FG ISL+ RR A TN LF L K+D + YP
Sbjct: 674 KSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTN--LFILDKKDLNEILVHYPESQ 731
Query: 120 ESIKKRA 126
+ ++K+A
Sbjct: 732 KLLRKKA 738
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 95 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 153
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 154 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 201
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 214 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 273
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 274 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 321
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 110 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 168
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 169 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 336
>BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein.
Length = 312
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 110 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 168
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 169 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
Score = 31.1 bits (67), Expect = 1.6
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 66 KE-----VCHLEDGDFFGAISL 82
+ L GD+FG +L
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKAL 310
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 110 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 168
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 169 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 336
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 83 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 141
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 142 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 189
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 202 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 261
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 262 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 309
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 110 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 168
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 169 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 336
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 83 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 141
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 142 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 189
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 202 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 261
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 262 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 309
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 110 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 168
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 169 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 336
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 83 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 141
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 142 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 189
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 202 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 261
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 262 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 309
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 110 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 168
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 169 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 229 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 288
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 289 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 336
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 44.8 bits (101), Expect = 1e-04
Identities = 25/108 (23%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSES 64
++ + + +F+K L + +I ++ V + I K VG VY ++ G V + E
Sbjct: 83 KEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTKE- 141
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
G ++C + G FG ++++ R T + N +L+ + ++ F + M
Sbjct: 142 GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 189
Score = 32.7 bits (71), Expect = 0.52
Identities = 24/108 (22%), Positives = 44/108 (40%), Gaps = 5/108 (4%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 202 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 261
Query: 66 KE-----VCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDF 108
+ L GD+FG +L R +A + ++ F
Sbjct: 262 PSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSF 309
>AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor
CNG-channel beta subunit protein.
Length = 1245
Score = 44.8 bits (101), Expect = 1e-04
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 9/127 (7%)
Query: 7 LVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS-ESG 65
+V +V + R ++ + +L V+++ D + K +G +Y I G V + G
Sbjct: 950 IVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDG 1009
Query: 66 KEVC-HLEDGDFFGAISLIL-----RRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVY 119
K V L+ G FG ISL+ RR A TN LF L K+D + YP
Sbjct: 1010 KSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTN--LFILDKKDLNEILVHYPESQ 1067
Query: 120 ESIKKRA 126
+ ++K+A
Sbjct: 1068 KLLRKKA 1074
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 43.6 bits (98), Expect = 3e-04
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 37 GDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-AV 95
G ++F G Y I KG+V + VC L +GD FG ++L+ R + V
Sbjct: 381 GTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLRE 440
Query: 96 TNCELFRLSKEDF 108
NC R+ KEDF
Sbjct: 441 DNCHFLRVDKEDF 453
>BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein.
Length = 867
Score = 43.6 bits (98), Expect = 3e-04
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 37 GDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-AV 95
G ++F G Y I KG+V + VC L +GD FG ++L+ R + V
Sbjct: 237 GTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLRE 296
Query: 96 TNCELFRLSKEDF 108
NC R+ KEDF
Sbjct: 297 DNCHFLRVDKEDF 309
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 43.6 bits (98), Expect = 3e-04
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 37 GDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-AV 95
G ++F G Y I KG+V + VC L +GD FG ++L+ R + V
Sbjct: 381 GTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLRE 440
Query: 96 TNCELFRLSKEDF 108
NC R+ KEDF
Sbjct: 441 DNCHFLRVDKEDF 453
>AB209681-1|BAD92918.1| 643|Homo sapiens RAP
guanine-nucleotide-exchange factor 4 variant protein.
Length = 643
Score = 43.6 bits (98), Expect = 3e-04
Identities = 27/81 (33%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 29 LHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFR 88
L + +FI ++F G Y I KG+V + VC L +GD FG ++L+ R
Sbjct: 5 LIISLFIFLCLVFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPR 64
Query: 89 LTTAV-AVTNCELFRLSKEDF 108
+ V NC R+ KEDF
Sbjct: 65 AASIVLREDNCHFLRVDKEDF 85
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 43.6 bits (98), Expect = 3e-04
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 37 GDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-AV 95
G ++F G Y I KG+V + VC L +GD FG ++L+ R + V
Sbjct: 381 GTVLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLRE 440
Query: 96 TNCELFRLSKEDF 108
NC R+ KEDF
Sbjct: 441 DNCHFLRVDKEDF 453
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 42.7 bits (96), Expect = 5e-04
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-A 94
AG ++F G Y I KG+V + + V L +GD FG ++L+ R T +
Sbjct: 227 AGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILR 286
Query: 95 VTNCELFRLSKEDF 108
NC R+ K+DF
Sbjct: 287 EDNCHFLRVDKQDF 300
>BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein.
Length = 343
Score = 42.7 bits (96), Expect = 5e-04
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-A 94
AG ++F G Y I KG+V + + V L +GD FG ++L+ R T +
Sbjct: 227 AGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILR 286
Query: 95 VTNCELFRLSKEDF 108
NC R+ K+DF
Sbjct: 287 EDNCHFLRVDKQDF 300
>BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein.
Length = 321
Score = 42.7 bits (96), Expect = 5e-04
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-A 94
AG ++F G Y I KG+V + + V L +GD FG ++L+ R T +
Sbjct: 227 AGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILR 286
Query: 95 VTNCELFRLSKEDF 108
NC R+ K+DF
Sbjct: 287 EDNCHFLRVDKQDF 300
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 42.7 bits (96), Expect = 5e-04
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-A 94
AG ++F G Y I KG+V + + V L +GD FG ++L+ R T +
Sbjct: 227 AGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILR 286
Query: 95 VTNCELFRLSKEDF 108
NC R+ K+DF
Sbjct: 287 EDNCHFLRVDKQDF 300
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 42.7 bits (96), Expect = 5e-04
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-A 94
AG ++F G Y I KG+V + + V L +GD FG ++L+ R T +
Sbjct: 227 AGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILR 286
Query: 95 VTNCELFRLSKEDF 108
NC R+ K+DF
Sbjct: 287 EDNCHFLRVDKQDF 300
>U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 556
Score = 42.3 bits (95), Expect = 6e-04
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-A 94
AG ++F G Y I KG+V + + V L +GD FG ++L+ R T +
Sbjct: 227 AGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILR 286
Query: 95 VTNCELFRLSKEDF 108
NC R+ K+DF
Sbjct: 287 EYNCHFLRVDKQDF 300
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 42.3 bits (95), Expect = 6e-04
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAV-A 94
AG ++F G Y I KG+V + + V L +GD FG ++L+ R T +
Sbjct: 227 AGTVLFSQGDKGTSWYIIWKGSVNVVTHGKGLVTTLHEGDDFGQLALVNDAPRAATIILR 286
Query: 95 VTNCELFRLSKEDF 108
NC R+ K+DF
Sbjct: 287 EYNCHFLRVDKQDF 300
>AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cyclic
nucleotide-gated channel beta subunit protein.
Length = 809
Score = 42.3 bits (95), Expect = 6e-04
Identities = 30/125 (24%), Positives = 53/125 (42%), Gaps = 5/125 (4%)
Query: 7 LVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS--ES 64
++ +V+ K ++ + +L V+++ GD + K +G +Y I G V + +
Sbjct: 518 IISKVDLFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDG 577
Query: 65 GKEVCHLEDGDFFGAISLILR---RFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYES 121
K + L+ G FG ISL+ R VA L L K+ + YP
Sbjct: 578 TKVLVTLKAGSVFGEISLLAAGGGNRRTANVVAHGFANLLTLDKKTLQEILVHYPDSERI 637
Query: 122 IKKRA 126
+ K+A
Sbjct: 638 LMKKA 642
>M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein
kinase type I-alpha subunit protein.
Length = 381
Score = 41.9 bits (94), Expect = 9e-04
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 32 VIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTT 91
V FIAG+ + + GD Y ID+G +Y + + + +G FG ++LI R T
Sbjct: 156 VSFIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTPRAAT 214
Query: 92 AVAVTNCELFRLSKEDF 108
A TN +L+ + ++ +
Sbjct: 215 VKAKTNVKLWGIDRDSY 231
>M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein
kinase regulatory subunit type 1 protein.
Length = 381
Score = 41.9 bits (94), Expect = 9e-04
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 32 VIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTT 91
V FIAG+ + + GD Y ID+G +Y + + + +G FG ++LI R T
Sbjct: 156 VSFIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTPRAAT 214
Query: 92 AVAVTNCELFRLSKEDF 108
A TN +L+ + ++ +
Sbjct: 215 VKAKTNVKLWGIDRDSY 231
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 41.9 bits (94), Expect = 9e-04
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 32 VIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTT 91
V FIAG+ + + GD Y ID+G +Y + + + +G FG ++LI R T
Sbjct: 156 VSFIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTPRAAT 214
Query: 92 AVAVTNCELFRLSKEDF 108
A TN +L+ + ++ +
Sbjct: 215 VKAKTNVKLWGIDRDSY 231
>BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 41.9 bits (94), Expect = 9e-04
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 32 VIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTT 91
V FIAG+ + + GD Y ID+G +Y + + + +G FG ++LI R T
Sbjct: 156 VSFIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTPRAAT 214
Query: 92 AVAVTNCELFRLSKEDF 108
A TN +L+ + ++ +
Sbjct: 215 VKAKTNVKLWGIDRDSY 231
>BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 41.9 bits (94), Expect = 9e-04
Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 32 VIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTT 91
V FIAG+ + + GD Y ID+G +Y + + + +G FG ++LI R T
Sbjct: 156 VSFIAGETVIQQGDEGDNFYVIDQGETDVY-VNNEWATSVGEGGSFGELALIYGTPRAAT 214
Query: 92 AVAVTNCELFRLSKEDF 108
A TN +L+ + ++ +
Sbjct: 215 VKAKTNVKLWGIDRDSY 231
>AF032897-1|AAD01946.1| 1196|Homo sapiens potassium channel subunit
protein.
Length = 1196
Score = 41.9 bits (94), Expect = 9e-04
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H + L++ + + + L + K + GD + V +YF+ +G++ I
Sbjct: 733 LHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHALQGDTLVHCGDVLTALYFLSRGSIEI 792
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
S++ V L D FG + L + + V A+T C+L ++ +ED + YP
Sbjct: 793 -SKNDMVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYP 849
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 40.7 bits (91), Expect = 0.002
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI-YSE 63
R +R V LK LP L +I L V + GD I + G + + KG V + S
Sbjct: 278 RNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQST 337
Query: 64 SGKE----VCHLEDGDFFGAISLILRRFRLTTAVAVTN-CELFRLSKEDFYSTMACYPTV 118
G + + L+ G++FG +LI R +A N + +E F T+ + +
Sbjct: 338 EGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEEL 397
Query: 119 YESIKKRAIN 128
+ ++ N
Sbjct: 398 QKYLEGYVAN 407
Score = 30.3 bits (65), Expect = 2.8
Identities = 20/101 (19%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
Query: 12 EFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHL 71
+FLK+L + + ++ + G I K G+ ++ + +G + ++ + K + +
Sbjct: 167 QFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVF-QGEKLLSSI 225
Query: 72 EDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
FG ++++ R + A+TN + + L +E F + M
Sbjct: 226 PMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIM 266
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 40.7 bits (91), Expect = 0.002
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI-YSE 63
R +R V LK LP L +I L V + GD I + G + + KG V + S
Sbjct: 278 RNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQST 337
Query: 64 SGKE----VCHLEDGDFFGAISLILRRFRLTTAVAVTN-CELFRLSKEDFYSTMACYPTV 118
G + + L+ G++FG +LI R +A N + +E F T+ + +
Sbjct: 338 EGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEEL 397
Query: 119 YESIKKRAIN 128
+ ++ N
Sbjct: 398 QKYLEGYVAN 407
Score = 30.3 bits (65), Expect = 2.8
Identities = 20/101 (19%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
Query: 12 EFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHL 71
+FLK+L + + ++ + G I K G+ ++ + +G + ++ + K + +
Sbjct: 167 QFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVF-QGEKLLSSI 225
Query: 72 EDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
FG ++++ R + A+TN + + L +E F + M
Sbjct: 226 PMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIM 266
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 40.7 bits (91), Expect = 0.002
Identities = 33/130 (25%), Positives = 55/130 (42%), Gaps = 6/130 (4%)
Query: 5 RQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI-YSE 63
R +R V LK LP L +I L V + GD I + G + + KG V + S
Sbjct: 278 RNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQST 337
Query: 64 SGKE----VCHLEDGDFFGAISLILRRFRLTTAVAVTN-CELFRLSKEDFYSTMACYPTV 118
G + + L+ G++FG +LI R +A N + +E F T+ + +
Sbjct: 338 EGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEEL 397
Query: 119 YESIKKRAIN 128
+ ++ N
Sbjct: 398 QKYLEGYVAN 407
Score = 30.3 bits (65), Expect = 2.8
Identities = 20/101 (19%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
Query: 12 EFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESGKEVCHL 71
+FLK+L + + ++ + G I K G+ ++ + +G + ++ + K + +
Sbjct: 167 QFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVF-QGEKLLSSI 225
Query: 72 EDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM 112
FG ++++ R + A+TN + + L +E F + M
Sbjct: 226 PMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIM 266
>S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein.
Length = 261
Score = 40.3 bits (90), Expect = 0.003
Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Query: 8 VREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG-K 66
+++V LLV++ KL +F GD I + +G +Y I +G +A+ ++ G
Sbjct: 158 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDGVT 217
Query: 67 EVCHLEDGDFFGAISLI 83
+ L G FG IS++
Sbjct: 218 QYALLSAGSCFGEISIL 234
>AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 39.9 bits (89), Expect = 0.003
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 40 IFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCE 99
I K VG VY ++ G V + E G ++C + G FG ++++ R T + N +
Sbjct: 3 IIKEGDVGSLVYVMEDGKVEVTKE-GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVK 61
Query: 100 LFRLSKEDFYSTM 112
L+ + ++ F + M
Sbjct: 62 LWAIDRQCFQTIM 74
Score = 31.1 bits (67), Expect = 1.6
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 87 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 146
Query: 66 KE-----VCHLEDGDFFGAISL 82
+ L GD+FG +L
Sbjct: 147 PSEDPVFLRTLGKGDWFGEKAL 168
>AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 39.9 bits (89), Expect = 0.003
Identities = 20/73 (27%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 40 IFKINSVGDCVYFIDKGTVAIYSESGKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCE 99
I K VG VY ++ G V + E G ++C + G FG ++++ R T + N +
Sbjct: 3 IIKEGDVGSLVYVMEDGKVEVTKE-GVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVK 61
Query: 100 LFRLSKEDFYSTM 112
L+ + ++ F + M
Sbjct: 62 LWAIDRQCFQTIM 74
Score = 31.1 bits (67), Expect = 1.6
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
Query: 6 QLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYSESG 65
+ ++ V + LP +L ++ L + G+ I + + GD + I KGTV + E
Sbjct: 87 EFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDS 146
Query: 66 KE-----VCHLEDGDFFGAISL 82
+ L GD+FG +L
Sbjct: 147 PSEDPVFLRTLGKGDWFGEKAL 168
>AK091877-1|BAC03764.1| 905|Homo sapiens protein ( Homo sapiens
cDNA FLJ34558 fis, clone KIDNE2001636, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 905
Score = 39.1 bits (87), Expect = 0.006
Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + L + K GD + + V +YFI +G++ I
Sbjct: 529 LHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEI 588
Query: 61 YSESGKEVCHLEDGDFFGA-ISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYPTV 118
+ V L D FG +SL + + + V A+T C+L ++ + D + YP
Sbjct: 589 LRDD-VVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYPAF 647
Query: 119 YES 121
ES
Sbjct: 648 AES 650
>AK090969-1|BAC03559.1| 430|Homo sapiens protein ( Homo sapiens
cDNA FLJ33650 fis, clone BRAMY2024514, highly similar to
Rattus norvegicus potassium channel (erg2) mRNA. ).
Length = 430
Score = 39.1 bits (87), Expect = 0.006
Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + L + K GD + + V +YFI +G++ I
Sbjct: 54 LHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEI 113
Query: 61 YSESGKEVCHLEDGDFFGA-ISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYPTV 118
+ V L D FG +SL + + + V A+T C+L ++ + D + YP
Sbjct: 114 LRDD-VVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYPAF 172
Query: 119 YES 121
ES
Sbjct: 173 AES 175
>AF311913-1|AAG40871.1| 994|Homo sapiens Eag-related gene member 2
protein.
Length = 994
Score = 39.1 bits (87), Expect = 0.006
Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + L + K GD + + V +YFI +G++ I
Sbjct: 582 LHLHRALLQHCPAFSGAGKGCLRALAVKFKTTHAPPGDTLVHLGDVLSTLYFISRGSIEI 641
Query: 61 YSESGKEVCHLEDGDFFGA-ISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYPTV 118
+ V L D FG +SL + + + V A+T C+L ++ + D + YP
Sbjct: 642 LRDD-VVVAILGKNDIFGEPVSLHAQPGKSSADVRALTYCDLHKIQRADLLEVLDMYPAF 700
Query: 119 YES 121
ES
Sbjct: 701 AES 703
>BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 38.3 bits (85), Expect = 0.010
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 9 REVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS---ESG 65
+E+ L ++ P L+ LH AG II + ++F+ G + +Y +
Sbjct: 462 QELAKLMRIEDPSLLNSRVLLHHAK--AGTIIARQGDQDVSLHFVLWGCLHVYQRMIDKA 519
Query: 66 KEVCHL--EDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTV 118
++VC + G+ G ++++ + T A +C R+SK DFY M P+V
Sbjct: 520 EDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSV 574
>BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 38.3 bits (85), Expect = 0.010
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 9 REVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS---ESG 65
+E+ L ++ P L+ LH AG II + ++F+ G + +Y +
Sbjct: 462 QELAKLMRIEDPSLLNSRVLLHHAK--AGTIIARQGDQDVSLHFVLWGCLHVYQRMIDKA 519
Query: 66 KEVCHL--EDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTV 118
++VC + G+ G ++++ + T A +C R+SK DFY M P+V
Sbjct: 520 EDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSV 574
>BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein.
Length = 1332
Score = 38.3 bits (85), Expect = 0.010
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 9 REVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS---ESG 65
+E+ L ++ P L+ LH AG II + ++F+ G + +Y +
Sbjct: 468 QELAKLMRIEDPSLLNSRVLLHHAK--AGTIIARQGDQDVSLHFVLWGCLHVYQRMIDKA 525
Query: 66 KEVCHL--EDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTV 118
++VC + G+ G ++++ + T A +C R+SK DFY M P+V
Sbjct: 526 EDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSV 580
>AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target esterase
protein.
Length = 1327
Score = 38.3 bits (85), Expect = 0.010
Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 7/115 (6%)
Query: 9 REVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS---ESG 65
+E+ L ++ P L+ LH AG II + ++F+ G + +Y +
Sbjct: 462 QELAKLMRIEDPSLLNSRVLLHHAK--AGTIIARQGDQDVSLHFVLWGCLHVYQRMIDKA 519
Query: 66 KEVCHL--EDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTV 118
++VC + G+ G ++++ + T A +C R+SK DFY M P+V
Sbjct: 520 EDVCLFVAQPGELVGQLAVLTGEPLIFTLRAQRDCTFLRISKSDFYEIMRAQPSV 574
>AC007740-1|AAX93153.1| 940|Homo sapiens unknown protein.
Length = 940
Score = 37.5 bits (83), Expect = 0.018
Identities = 26/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H + L++ + + + L + K GD + V +YF+ +G++ I
Sbjct: 630 LHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEI 689
Query: 61 YSESGKEVCHLEDGDFFGA-ISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
+ V L D FG + L + + V A+T C+L ++ +ED + YP
Sbjct: 690 LKDD-IVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYP 746
>U04270-1|AAA62473.1| 1159|Homo sapiens putative potassium channel
subunit protein.
Length = 1159
Score = 36.7 bits (81), Expect = 0.032
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + + + L + K GD + + +YFI +G++ I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
V L D FG ++L R + V A+T C+L ++ ++D + YP
Sbjct: 790 L-RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
>DQ784808-1|ABQ01243.1| 1159|Homo sapiens potassium voltage-gated
channel subfamily H member 2 protein.
Length = 1159
Score = 36.7 bits (81), Expect = 0.032
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + + + L + K GD + + +YFI +G++ I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
V L D FG ++L R + V A+T C+L ++ ++D + YP
Sbjct: 790 L-RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
>DQ525913-1|ABF71886.1| 1159|Homo sapiens voltage-gated potassium
channel KV11.1 transcript variant 1 protein.
Length = 1159
Score = 36.7 bits (81), Expect = 0.032
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + + + L + K GD + + +YFI +G++ I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
V L D FG ++L R + V A+T C+L ++ ++D + YP
Sbjct: 790 L-RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
>BC004311-1|AAH04311.2| 444|Homo sapiens KCNH2 protein protein.
Length = 444
Score = 36.7 bits (81), Expect = 0.032
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + + + L + K GD + + +YFI +G++ I
Sbjct: 15 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 74
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
V L D FG ++L R + V A+T C+L ++ ++D + YP
Sbjct: 75 L-RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 131
>AJ512214-1|CAD54447.1| 819|Homo sapiens potassium channel 1b
protein protein.
Length = 819
Score = 36.7 bits (81), Expect = 0.032
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + + + L + K GD + + +YFI +G++ I
Sbjct: 390 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 449
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
V L D FG ++L R + V A+T C+L ++ ++D + YP
Sbjct: 450 L-RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 506
>AJ010538-1|CAA09232.1| 1133|Homo sapiens ether-a-go-go-related
protein protein.
Length = 1133
Score = 36.7 bits (81), Expect = 0.032
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + + + L + K GD + + +YFI +G++ I
Sbjct: 704 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 763
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
V L D FG ++L R + V A+T C+L ++ ++D + YP
Sbjct: 764 L-RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 820
>AF363636-1|AAL37559.1| 1159|Homo sapiens ether-a-go-go-related K+
channel protein protein.
Length = 1159
Score = 36.7 bits (81), Expect = 0.032
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + + + L + K GD + + +YFI +G++ I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
V L D FG ++L R + V A+T C+L ++ ++D + YP
Sbjct: 790 L-RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
>AB009071-1|BAA37096.1| 1159|Homo sapiens HERG protein.
Length = 1159
Score = 36.7 bits (81), Expect = 0.032
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 1 MHTGRQLVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAI 60
+H R L++ + + + L + K GD + + +YFI +G++ I
Sbjct: 730 LHLNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEI 789
Query: 61 YSESGKEVCHLEDGDFFG-AISLILRRFRLTTAV-AVTNCELFRLSKEDFYSTMACYP 116
V L D FG ++L R + V A+T C+L ++ ++D + YP
Sbjct: 790 L-RGDVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVLDMYP 846
>BC114945-1|AAI14946.1| 423|Homo sapiens C20orf152 protein protein.
Length = 423
Score = 33.9 bits (74), Expect = 0.23
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 39 IIFKINSVGDCVYFIDKGTVAIYS-ESGKEVC---H---LEDGDFFGAISLILRRFRLTT 91
+I K G+ YFI GTVAI E G H L G FG + ++ R +T
Sbjct: 142 VIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRST 201
Query: 92 AVAVTNCELFRLSKEDFYS 110
V + E + +EDF++
Sbjct: 202 IVCMEETEFLVVDREDFFA 220
>AL359828-2|CAI23442.1| 572|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 572
Score = 33.9 bits (74), Expect = 0.23
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 39 IIFKINSVGDCVYFIDKGTVAIYS-ESGKEVC---H---LEDGDFFGAISLILRRFRLTT 91
+I K G+ YFI GTVAI E G H L G FG + ++ R +T
Sbjct: 142 VIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRST 201
Query: 92 AVAVTNCELFRLSKEDFYS 110
V + E + +EDF++
Sbjct: 202 IVCMEETEFLVVDREDFFA 220
>AL359828-1|CAI23441.1| 576|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 576
Score = 33.9 bits (74), Expect = 0.23
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 39 IIFKINSVGDCVYFIDKGTVAIYS-ESGKEVC---H---LEDGDFFGAISLILRRFRLTT 91
+I K G+ YFI GTVAI E G H L G FG + ++ R +T
Sbjct: 142 VIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRST 201
Query: 92 AVAVTNCELFRLSKEDFYS 110
V + E + +EDF++
Sbjct: 202 IVCMEETEFLVVDREDFFA 220
>AL109965-6|CAI19249.1| 572|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 572
Score = 33.9 bits (74), Expect = 0.23
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 39 IIFKINSVGDCVYFIDKGTVAIYS-ESGKEVC---H---LEDGDFFGAISLILRRFRLTT 91
+I K G+ YFI GTVAI E G H L G FG + ++ R +T
Sbjct: 142 VIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRST 201
Query: 92 AVAVTNCELFRLSKEDFYS 110
V + E + +EDF++
Sbjct: 202 IVCMEETEFLVVDREDFFA 220
>AL109965-5|CAI19248.1| 576|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 576
Score = 33.9 bits (74), Expect = 0.23
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 39 IIFKINSVGDCVYFIDKGTVAIYS-ESGKEVC---H---LEDGDFFGAISLILRRFRLTT 91
+I K G+ YFI GTVAI E G H L G FG + ++ R +T
Sbjct: 142 VIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRST 201
Query: 92 AVAVTNCELFRLSKEDFYS 110
V + E + +EDF++
Sbjct: 202 IVCMEETEFLVVDREDFFA 220
>AK057454-1|BAB71494.1| 572|Homo sapiens protein ( Homo sapiens
cDNA FLJ32892 fis, clone TESTI2004982, weakly similar to
CGMP-DEPENDENT PROTEIN KINASE 1, ALPHA ISOZYME (EC
2.7.1.37). ).
Length = 572
Score = 33.9 bits (74), Expect = 0.23
Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 7/79 (8%)
Query: 39 IIFKINSVGDCVYFIDKGTVAIYS-ESGKEVC---H---LEDGDFFGAISLILRRFRLTT 91
+I K G+ YFI GTVAI E G H L G FG + ++ R +T
Sbjct: 142 VIIKKGQKGNSFYFIYLGTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRST 201
Query: 92 AVAVTNCELFRLSKEDFYS 110
V + E + +EDF++
Sbjct: 202 IVCMEETEFLVVDREDFFA 220
>AL365502-7|CAI14582.1| 1317|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 1317
Score = 33.1 bits (72), Expect = 0.39
Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSE---SGKEVCHL--EDGDFFGAISLILRRFRLT 90
AG ++ + + F+ G + +Y S ++ C G+ G ++++ +
Sbjct: 482 AGTVVSRQGDQDASILFVVSGLLHVYQRKIGSQEDTCLFLTRPGEMVGQLAVLTGEPLIF 541
Query: 91 TAVAVTNCELFRLSKEDFYSTMACYPTVYESIKKRAINR 129
T A +C +SK FY M PTV + + R
Sbjct: 542 TVKANRDCSFLSISKAHFYEIMRKQPTVVLGVAHTVVKR 580
>AL365502-6|CAI14581.1| 1281|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 1281
Score = 33.1 bits (72), Expect = 0.39
Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSE---SGKEVCHL--EDGDFFGAISLILRRFRLT 90
AG ++ + + F+ G + +Y S ++ C G+ G ++++ +
Sbjct: 473 AGTVVSRQGDQDASILFVVSGLLHVYQRKIGSQEDTCLFLTRPGEMVGQLAVLTGEPLIF 532
Query: 91 TAVAVTNCELFRLSKEDFYSTMACYPTVYESIKKRAINR 129
T A +C +SK FY M PTV + + R
Sbjct: 533 TVKANRDCSFLSISKAHFYEIMRKQPTVVLGVAHTVVKR 571
>AL365502-5|CAI14579.1| 923|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 923
Score = 33.1 bits (72), Expect = 0.39
Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSE---SGKEVCHL--EDGDFFGAISLILRRFRLT 90
AG ++ + + F+ G + +Y S ++ C G+ G ++++ +
Sbjct: 88 AGTVVSRQGDQDASILFVVSGLLHVYQRKIGSQEDTCLFLTRPGEMVGQLAVLTGEPLIF 147
Query: 91 TAVAVTNCELFRLSKEDFYSTMACYPTVYESIKKRAINR 129
T A +C +SK FY M PTV + + R
Sbjct: 148 TVKANRDCSFLSISKAHFYEIMRKQPTVVLGVAHTVVKR 186
>AK125060-1|BAC86036.1| 1317|Homo sapiens protein ( Homo sapiens
cDNA FLJ43070 fis, clone BRTHA3009090, moderately
similar to Homo sapiens neuropathy target esterase
(NTE). ).
Length = 1317
Score = 33.1 bits (72), Expect = 0.39
Identities = 21/99 (21%), Positives = 40/99 (40%), Gaps = 5/99 (5%)
Query: 36 AGDIIFKINSVGDCVYFIDKGTVAIYSE---SGKEVCHL--EDGDFFGAISLILRRFRLT 90
AG ++ + + F+ G + +Y S ++ C G+ G ++++ +
Sbjct: 482 AGTVVSRQGDQDASILFVVSGLLHVYQRKIGSQEDTCLFLTRPGEMVGQLAVLTGEPLIF 541
Query: 91 TAVAVTNCELFRLSKEDFYSTMACYPTVYESIKKRAINR 129
T A +C +SK FY M PTV + + R
Sbjct: 542 TVKANRDCSFLSISKAHFYEIMRKQPTVVLGVAHTVVKR 580
>AF228520-1|AAF80179.1| 610|Homo sapiens cone photoreceptor
cGMP-gated cation channel beta-subunit protein.
Length = 610
Score = 32.7 bits (71), Expect = 0.52
Identities = 27/122 (22%), Positives = 49/122 (40%), Gaps = 4/122 (3%)
Query: 7 LVREVEFLKQLPRPLLVQIGFKLHVVIFIAGDIIFKINSVGDCVYFIDKGTVAIYS--ES 64
++ +V+ K ++ + +L V+++ GD + K +G +Y I G V + +
Sbjct: 324 IISKVDLFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHGEVQVLGGPDG 383
Query: 65 GKEVCHLEDGDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTMACYPTVYESIKK 124
K + L+ G A RR A N L L K+ + YP + K
Sbjct: 384 TKVLVTLKAGSVLLAAGGGNRRTANVVAHGFAN--LLTLDKKTLQEILVHYPDSERILMK 441
Query: 125 RA 126
+A
Sbjct: 442 KA 443
>Z84814-4|CAC69895.2| 243|Homo sapiens butyrophilin-like 2 (MHC
class II associated) protein.
Length = 243
Score = 29.9 bits (64), Expect = 3.7
Identities = 12/34 (35%), Positives = 23/34 (67%)
Query: 62 SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAV 95
S++G+ CH +DG++ G SL+L+ L +A ++
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSI 150
>BX255945-4|CAI18727.2| 259|Homo sapiens butyrophilin-like 2 (MHC
class II associated) protein.
Length = 259
Score = 29.9 bits (64), Expect = 3.7
Identities = 12/34 (35%), Positives = 23/34 (67%)
Query: 62 SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAV 95
S++G+ CH +DG++ G SL+L+ L +A ++
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSI 150
>AL935032-3|CAI18475.2| 259|Homo sapiens butyrophilin-like 2 (MHC
class II associated) protein.
Length = 259
Score = 29.9 bits (64), Expect = 3.7
Identities = 12/34 (35%), Positives = 23/34 (67%)
Query: 62 SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAV 95
S++G+ CH +DG++ G SL+L+ L +A ++
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSI 150
>AL670296-4|CAI17570.2| 259|Homo sapiens butyrophilin-like 2 (MHC
class II associated) protein.
Length = 259
Score = 29.9 bits (64), Expect = 3.7
Identities = 12/34 (35%), Positives = 23/34 (67%)
Query: 62 SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAV 95
S++G+ CH +DG++ G SL+L+ L +A ++
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSI 150
>AL662796-4|CAI18265.2| 259|Homo sapiens butyrophilin-like 2 (MHC
class II associated) protein.
Length = 259
Score = 29.9 bits (64), Expect = 3.7
Identities = 12/34 (35%), Positives = 23/34 (67%)
Query: 62 SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAV 95
S++G+ CH +DG++ G SL+L+ L +A ++
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSI 150
>AL034394-4|CAI42180.1| 243|Homo sapiens butyrophilin-like 2 (MHC
class II associated) protein.
Length = 243
Score = 29.9 bits (64), Expect = 3.7
Identities = 12/34 (35%), Positives = 23/34 (67%)
Query: 62 SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAV 95
S++G+ CH +DG++ G SL+L+ L +A ++
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSI 150
>AF186593-1|AAF05530.1| 455|Homo sapiens butyrophilin-like protein.
Length = 455
Score = 29.9 bits (64), Expect = 3.7
Identities = 12/34 (35%), Positives = 23/34 (67%)
Query: 62 SESGKEVCHLEDGDFFGAISLILRRFRLTTAVAV 95
S++G+ CH +DG++ G SL+L+ L +A ++
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLKVAGLGSAPSI 150
>BC042592-1|AAH42592.1| 1124|Homo sapiens solute carrier family 9,
member 11 protein.
Length = 1124
Score = 29.1 bits (62), Expect = 6.4
Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
Query: 74 GDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM-ACYPTV-YESIKKRAIN--- 128
GD G +S +L+R T + T+ + +S ED Y A +P++ Y+ K A++
Sbjct: 944 GDIIGELSCLLKREIEYTVICETSLQACFISLEDLYEGFDAFWPSLEYKIWLKLALSTAY 1003
Query: 129 RYEETCVLDE 138
+Y E+ ++DE
Sbjct: 1004 QYFESSLIDE 1013
>AY881999-2|AAX35330.1| 270|Homo sapiens butyrophyllin-like protein
2 short form protein.
Length = 270
Score = 29.1 bits (62), Expect = 6.4
Identities = 10/24 (41%), Positives = 18/24 (75%)
Query: 62 SESGKEVCHLEDGDFFGAISLILR 85
S++G+ CH +DG++ G SL+L+
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLK 140
>AY881999-1|AAX35331.1| 388|Homo sapiens butyrophyllin-like protein
2 long form protein.
Length = 388
Score = 29.1 bits (62), Expect = 6.4
Identities = 10/24 (41%), Positives = 18/24 (75%)
Query: 62 SESGKEVCHLEDGDFFGAISLILR 85
S++G+ CH +DG++ G SL+L+
Sbjct: 117 SDNGQYWCHFQDGNYCGETSLLLK 140
>AL139142-3|CAI20938.1| 1124|Homo sapiens solute carrier family 9,
member 11 protein.
Length = 1124
Score = 29.1 bits (62), Expect = 6.4
Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
Query: 74 GDFFGAISLILRRFRLTTAVAVTNCELFRLSKEDFYSTM-ACYPTV-YESIKKRAIN--- 128
GD G +S +L+R T + T+ + +S ED Y A +P++ Y+ K A++
Sbjct: 944 GDIIGELSCLLKREIEYTVICETSLQACFISLEDLYEGFDAFWPSLEYKIWLKLALSTAY 1003
Query: 129 RYEETCVLDE 138
+Y E+ ++DE
Sbjct: 1004 QYFESSLIDE 1013
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.326 0.141 0.418
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 19,534,977
Number of Sequences: 224733
Number of extensions: 714632
Number of successful extensions: 4773
Number of sequences better than 10.0: 110
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 4605
Number of HSP's gapped (non-prelim): 136
length of query: 149
length of database: 73,234,838
effective HSP length: 83
effective length of query: 66
effective length of database: 54,581,999
effective search space: 3602411934
effective search space used: 3602411934
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.7 bits)
S2: 61 (28.7 bits)
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