Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005208-TA|BGIBMGA005208-PA|IPR002198|Short-chain
dehydrogenase/reductase SDR, IPR002347|Glucose/ribitol dehydrogenase
(295 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 219 7e-57
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 219 7e-57
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 219 7e-57
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 219 7e-57
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 219 7e-57
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 219 7e-57
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 219 7e-57
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 219 1e-56
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 215 2e-55
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 215 2e-55
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 199 1e-50
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 199 1e-50
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 199 1e-50
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 199 1e-50
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 198 3e-50
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 195 2e-49
BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein. 185 2e-46
AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein. 172 1e-42
AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing ox... 163 7e-40
AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein. 163 7e-40
AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing pr... 163 7e-40
BC015582-1|AAH15582.1| 327|Homo sapiens dehydrogenase/reductase... 149 1e-35
AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein. 147 4e-35
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 147 5e-35
AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein. 146 1e-34
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 131 3e-30
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 128 2e-29
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 128 2e-29
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 128 3e-29
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 128 3e-29
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 113 7e-25
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 113 7e-25
BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein. 112 2e-24
AF217490-1|AAF78197.1| 191|Homo sapiens fragile 16D oxido reduc... 92 2e-18
CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase... 91 4e-18
BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase... 91 4e-18
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 87 9e-17
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 87 9e-17
AL137300-1|CAB70685.1| 204|Homo sapiens hypothetical protein pr... 73 2e-12
AL162377-1|CAI13427.1| 242|Homo sapiens dehydrogenase/reductase... 64 4e-10
AL136525-2|CAH70586.1| 242|Homo sapiens dehydrogenase/reductase... 64 4e-10
AK023701-1|BAB14646.1| 242|Homo sapiens protein ( Homo sapiens ... 64 4e-10
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 64 6e-10
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 64 6e-10
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 64 6e-10
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 64 6e-10
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 64 6e-10
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 64 6e-10
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 64 6e-10
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 64 6e-10
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 64 6e-10
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 64 6e-10
BC009825-1|AAH09825.1| 271|Homo sapiens dehydrogenase/reductase... 63 1e-09
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 62 2e-09
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 62 2e-09
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 61 4e-09
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 61 4e-09
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 61 4e-09
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 61 4e-09
AF325429-1|AAL05450.1| 189|Homo sapiens WW domain-containing ox... 61 5e-09
AF227528-1|AAF82055.1| 189|Homo sapiens FOR III protein protein. 61 5e-09
AF187015-1|AAF31694.1| 189|Homo sapiens truncated WW-domain oxi... 61 5e-09
BT007445-1|AAP36113.1| 234|Homo sapiens WW domain containing ox... 60 7e-09
BC003184-1|AAH03184.1| 234|Homo sapiens WWOX protein protein. 60 7e-09
AF395123-1|AAK81727.1| 234|Homo sapiens WWOXdelta6-8 protein. 60 7e-09
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 60 1e-08
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 60 1e-08
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 60 1e-08
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 60 1e-08
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 60 1e-08
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 59 2e-08
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 59 2e-08
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 59 2e-08
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 59 2e-08
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 59 2e-08
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 59 2e-08
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 59 2e-08
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 59 2e-08
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 59 2e-08
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 59 2e-08
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 59 2e-08
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 59 2e-08
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 59 2e-08
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 59 2e-08
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 59 2e-08
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 59 2e-08
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 58 4e-08
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 58 4e-08
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 58 4e-08
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 57 6e-08
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 57 6e-08
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 57 6e-08
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 54 5e-07
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 54 5e-07
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 54 5e-07
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 54 5e-07
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 54 5e-07
U13395-1|AAA21465.1| 370|Homo sapiens oxidoreductase protein. 54 6e-07
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 54 6e-07
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 54 6e-07
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 54 6e-07
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 54 8e-07
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 54 8e-07
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 53 1e-06
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 53 1e-06
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 53 1e-06
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 53 1e-06
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 53 1e-06
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 52 2e-06
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 52 2e-06
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 52 2e-06
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 52 2e-06
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 52 2e-06
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 52 2e-06
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 52 2e-06
BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein. 52 2e-06
AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid d... 52 2e-06
AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid ... 52 2e-06
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 52 3e-06
AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid d... 51 4e-06
AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protei... 51 4e-06
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 51 6e-06
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 51 6e-06
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 51 6e-06
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 51 6e-06
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 51 6e-06
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 51 6e-06
AF162767-1|AAF14537.1| 341|Homo sapiens 17beta-hydroxysteroid d... 51 6e-06
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 51 6e-06
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 50 1e-05
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 49 2e-05
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 49 2e-05
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 49 2e-05
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 49 2e-05
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 49 2e-05
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 49 2e-05
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 49 2e-05
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 49 2e-05
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 49 2e-05
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 49 2e-05
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 49 2e-05
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 49 2e-05
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 49 2e-05
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 49 2e-05
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 49 2e-05
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 49 2e-05
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 48 3e-05
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 48 4e-05
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 48 4e-05
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 48 5e-05
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 48 5e-05
AL162732-2|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 48 5e-05
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 47 9e-05
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 46 1e-04
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 46 1e-04
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 46 1e-04
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 46 1e-04
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 46 2e-04
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 46 2e-04
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 46 2e-04
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 46 2e-04
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 46 2e-04
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 46 2e-04
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 46 2e-04
BC064525-1|AAH64525.1| 309|Homo sapiens retinal short chain deh... 46 2e-04
BC037219-1|AAH37219.2| 309|Homo sapiens retinal short chain deh... 46 2e-04
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 46 2e-04
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 46 2e-04
AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta... 46 2e-04
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 46 2e-04
AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens ... 46 2e-04
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 45 3e-04
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 45 3e-04
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 45 3e-04
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 45 3e-04
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 45 3e-04
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 44 5e-04
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 44 5e-04
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 44 5e-04
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 44 5e-04
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 44 5e-04
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 44 5e-04
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 44 5e-04
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 44 5e-04
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 44 6e-04
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 44 6e-04
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 44 6e-04
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 44 6e-04
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 44 6e-04
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 43 0.001
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 43 0.001
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 43 0.001
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 43 0.001
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 43 0.001
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 43 0.001
AL023881-2|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 43 0.001
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 43 0.001
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 43 0.001
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 43 0.001
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 43 0.001
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxyacyl-Coenzyme A de... 43 0.001
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 43 0.001
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 43 0.001
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 43 0.001
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 43 0.001
AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid ... 43 0.001
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 43 0.001
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 43 0.001
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 43 0.001
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 42 0.003
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 42 0.003
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 41 0.005
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 41 0.005
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 41 0.005
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 41 0.006
AL445197-6|CAI15944.1| 84|Homo sapiens hydroxysteroid (17-beta... 41 0.006
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 40 0.008
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 40 0.008
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 40 0.008
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 40 0.008
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 40 0.008
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 40 0.008
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 40 0.008
Z97054-9|CAI42652.1| 252|Homo sapiens hydroxyacyl-Coenzyme A de... 39 0.018
Z97054-7|CAI42651.1| 169|Homo sapiens hydroxyacyl-Coenzyme A de... 39 0.018
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 39 0.018
BC071987-1|AAH71987.1| 229|Homo sapiens HSD17B7P2 protein protein. 39 0.024
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 39 0.024
BC012536-1|AAH12536.1| 98|Homo sapiens HSD17B12 protein protein. 39 0.024
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 39 0.024
AY829267-1|AAV87307.1| 229|Homo sapiens 17beta-hydroxysteroid d... 39 0.024
AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid ... 39 0.024
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 39 0.024
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 39 0.024
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 39 0.024
AF165514-1|AAF86644.1| 111|Homo sapiens 17-beta-hydroxysteroid ... 39 0.024
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 39 0.024
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.032
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 38 0.032
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.032
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.032
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.032
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 38 0.032
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 38 0.032
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 38 0.032
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 38 0.056
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 38 0.056
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 38 0.056
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 38 0.056
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 38 0.056
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 38 0.056
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 38 0.056
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 38 0.056
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 38 0.056
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 38 0.056
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 38 0.056
AL645940-11|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 38 0.056
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 38 0.056
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 38 0.056
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 38 0.056
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 37 0.074
AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent 15-hydro... 37 0.097
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 36 0.13
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 36 0.13
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 36 0.13
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 36 0.17
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 36 0.23
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 36 0.23
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 36 0.23
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 35 0.30
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 35 0.30
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 35 0.30
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 35 0.30
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 35 0.30
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 35 0.30
AK126701-1|BAC86649.1| 173|Homo sapiens protein ( Homo sapiens ... 35 0.39
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 34 0.52
BC018336-1|AAH18336.1| 87|Homo sapiens Unknown (protein for MG... 33 1.2
DQ426869-1|ABD90534.1| 69|Homo sapiens dehydrogenase/reductase... 33 1.6
AY358093-1|AAQ88460.1| 152|Homo sapiens SDR1 protein. 33 1.6
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 32 2.1
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 32 2.1
M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid de... 32 2.8
AY444559-1|AAS68535.1| 265|Homo sapiens retinal short chain deh... 31 3.7
AY333288-1|AAR03493.1| 569|Homo sapiens M6-kinase 3 protein. 31 3.7
AY333287-1|AAR03492.1| 855|Homo sapiens M6-kinase 2 protein. 31 3.7
AY333286-1|AAR03491.1| 973|Homo sapiens M6-kinase 1 protein. 31 3.7
AY333285-1|AAR03490.1| 1943|Homo sapiens truncated transient rec... 31 3.7
AY333284-1|AAR03489.1| 2017|Homo sapiens transient receptor pote... 31 3.7
AY333283-1|AAR03488.1| 2017|Homo sapiens transient receptor pote... 31 3.7
AY333282-1|AAR03487.1| 2022|Homo sapiens transient receptor pote... 31 3.7
AL354795-3|CAH70895.1| 303|Homo sapiens transient receptor pote... 31 3.7
AL354795-2|CAH70894.1| 2022|Homo sapiens transient receptor pote... 31 3.7
AK057748-1|BAB71558.1| 303|Homo sapiens protein ( Homo sapiens ... 31 3.7
AF448232-1|AAM21562.1| 2022|Homo sapiens LTRPC6 channel kinase 2... 31 3.7
AF350881-1|AAK31202.2| 2022|Homo sapiens channel-kinase 2 protein. 31 3.7
AL162571-2|CAI39591.1| 1298|Homo sapiens TBC1 domain family, mem... 31 4.8
AL139230-1|CAH70991.1| 1298|Homo sapiens TBC1 domain family, mem... 31 4.8
AB011175-1|BAA25529.2| 1348|Homo sapiens KIAA0603 protein protein. 31 4.8
AF325432-2|AAL05451.1| 213|Homo sapiens aberrant WW domain-cont... 31 6.4
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 219 bits (536), Expect = 7e-57
Identities = 118/286 (41%), Positives = 172/286 (60%), Gaps = 4/286 (1%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNVSS+ + G I+F + + FYN L YC+SKL N++
Sbjct: 152 GHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 211
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 212 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 268
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 269 HCALTEGLEILSGNHFSDC-HVAWVSAQARNETIARRLWDVSCDLL 313
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 219 bits (536), Expect = 7e-57
Identities = 118/286 (41%), Positives = 172/286 (60%), Gaps = 4/286 (1%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNVSS+ + G I+F + + FYN L YC+SKL N++
Sbjct: 152 GHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 211
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 212 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 268
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 269 HCALTEGLEILSGNHFSDC-HVAWVSAQARNETIARRLWDVSCDLL 313
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 219 bits (536), Expect = 7e-57
Identities = 118/286 (41%), Positives = 172/286 (60%), Gaps = 4/286 (1%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNVSS+ + G I+F + + FYN L YC+SKL N++
Sbjct: 152 GHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 211
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 212 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 268
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 269 HCALTEGLEILSGNHFSDC-HVAWVSAQARNETIARRLWDVSCDLL 313
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 219 bits (536), Expect = 7e-57
Identities = 118/286 (41%), Positives = 172/286 (60%), Gaps = 4/286 (1%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNVSS+ + G I+F + + FYN L YC+SKL N++
Sbjct: 152 GHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 211
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 212 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 268
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 269 HCALTEGLEILSGNHFSDC-HVAWVSAQARNETIARRLWDVSCDLL 313
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 219 bits (536), Expect = 7e-57
Identities = 118/286 (41%), Positives = 172/286 (60%), Gaps = 4/286 (1%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNVSS+ + G I+F + + FYN L YC+SKL N++
Sbjct: 152 GHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 211
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 212 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 268
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 269 HCALTEGLEILSGNHFSDC-HVAWVSAQARNETIARRLWDVSCDLL 313
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 219 bits (536), Expect = 7e-57
Identities = 118/286 (41%), Positives = 172/286 (60%), Gaps = 4/286 (1%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNVSS+ + G I+F + + FYN L YC+SKL N++
Sbjct: 152 GHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 211
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 212 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 268
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 269 HCALTEGLEILSGNHFSDC-HVAWVSAQARNETIARRLWDVSCDLL 313
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 219 bits (536), Expect = 7e-57
Identities = 118/286 (41%), Positives = 172/286 (60%), Gaps = 4/286 (1%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNVSS+ + G I+F + + FYN L YC+SKL N++
Sbjct: 152 GHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 211
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 212 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 268
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 269 HCALTEGLEILSGNHFSDC-HVAWVSAQARNETIARRLWDVSCDLL 313
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 219 bits (535), Expect = 1e-56
Identities = 118/286 (41%), Positives = 172/286 (60%), Gaps = 4/286 (1%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNVSS+ + G I+F + + FYN L YC+SKL N++
Sbjct: 152 GHFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 211
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 212 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 268
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 269 HCALTEGLEILSGNHFSDC-HVAWVSVQARNETIARRLWDVSCDLL 313
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 215 bits (524), Expect = 2e-55
Identities = 117/288 (40%), Positives = 174/288 (60%), Gaps = 8/288 (2%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C NV + G+VV++TGAN+GIG +TA++LA RGARV + CR V +G A EI T N
Sbjct: 30 VCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKN 89
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
V+ +++DLS +S+R FA+ + E +LH+LINNAG+ S T DG +T + VN+
Sbjct: 90 SQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHL 149
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K S P+R+VNVSS+ + G I F D + Y+ YC+SKL N++
Sbjct: 150 GHFLLTYLLLEQLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVL 209
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCS--NLLYRVGFAVLCWFNNLTDEDGAQT 238
FT EL++RL+ TGV AVHPG++ + + S LL+R+ F+ T +GAQT
Sbjct: 210 FTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRL-FSPFV----KTAREGAQT 264
Query: 239 PLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
LH A ++ +GK+F +C + + VSP+ RN ++LW S +L+
Sbjct: 265 SLHCALAEGLEPLSGKYFSDC-KRTWVSPRARNNKTAERLWNVSCELL 311
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 215 bits (524), Expect = 2e-55
Identities = 117/288 (40%), Positives = 174/288 (60%), Gaps = 8/288 (2%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C NV + G+VV++TGAN+GIG +TA++LA RGARV + CR V +G A EI T N
Sbjct: 30 VCRTNVQLPGKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKN 89
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
V+ +++DLS +S+R FA+ + E +LH+LINNAG+ S T DG +T + VN+
Sbjct: 90 SQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHL 149
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K S P+R+VNVSS+ + G I F D + Y+ YC+SKL N++
Sbjct: 150 GHFLLTYLLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVL 209
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCS--NLLYRVGFAVLCWFNNLTDEDGAQT 238
FT EL++RL+ TGV AVHPG++ + + S LL+R+ F+ T +GAQT
Sbjct: 210 FTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRL-FSPFV----KTAREGAQT 264
Query: 239 PLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
LH A ++ +GK+F +C + + VSP+ RN ++LW S +L+
Sbjct: 265 SLHCALAEGLEPLSGKYFSDC-KRTWVSPRARNNKTAERLWNVSCELL 311
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 199 bits (485), Expect = 1e-50
Identities = 115/293 (39%), Positives = 165/293 (56%), Gaps = 15/293 (5%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEII------------ 55
M G+ V++TGANSG+G TA +L R GARVI+GCR R +A ++
Sbjct: 41 MHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPE 100
Query: 56 -SVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTV 114
V+ ++ +++DL+SLRSVR F +++++ E L VLINNAG+F TEDG +
Sbjct: 101 PGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQ 160
Query: 115 MQVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNS 174
VN+ G F K S PSRIV VSS +G INF D N + YN Y S
Sbjct: 161 FGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRS 220
Query: 175 KLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNGCS-NLLYRVGFAVLCWFNNLTDE 233
KL N++FT EL+ RL T V VN +HPGI+ TN+ LL + F ++ W T
Sbjct: 221 KLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPV 280
Query: 234 DGAQTPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
+GAQT ++LA+S +G++F +C E L+ PK +E + +KLW+ S ++
Sbjct: 281 EGAQTSIYLASSPEVEGVSGRYFGDCKEEELL-PKAMDESVARKLWDISEVMV 332
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 199 bits (485), Expect = 1e-50
Identities = 115/293 (39%), Positives = 165/293 (56%), Gaps = 15/293 (5%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEII------------ 55
M G+ V++TGANSG+G TA +L R GARVI+GCR R +A ++
Sbjct: 41 MHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPE 100
Query: 56 -SVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTV 114
V+ ++ +++DL+SLRSVR F +++++ E L VLINNAG+F TEDG +
Sbjct: 101 PGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQ 160
Query: 115 MQVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNS 174
VN+ G F K S PSRIV VSS +G INF D N + YN Y S
Sbjct: 161 FGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRS 220
Query: 175 KLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNGCS-NLLYRVGFAVLCWFNNLTDE 233
KL N++FT EL+ RL T V VN +HPGI+ TN+ LL + F ++ W T
Sbjct: 221 KLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPV 280
Query: 234 DGAQTPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
+GAQT ++LA+S +G++F +C E L+ PK +E + +KLW+ S ++
Sbjct: 281 EGAQTSIYLASSPEVEGVSGRYFGDCKEEELL-PKAMDESVARKLWDISEVMV 332
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 199 bits (485), Expect = 1e-50
Identities = 115/293 (39%), Positives = 165/293 (56%), Gaps = 15/293 (5%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEII------------ 55
M G+ V++TGANSG+G TA +L R GARVI+GCR R +A ++
Sbjct: 41 MHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPE 100
Query: 56 -SVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTV 114
V+ ++ +++DL+SLRSVR F +++++ E L VLINNAG+F TEDG +
Sbjct: 101 PGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQ 160
Query: 115 MQVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNS 174
VN+ G F K S PSRIV VSS +G INF D N + YN Y S
Sbjct: 161 FGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRS 220
Query: 175 KLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNGCS-NLLYRVGFAVLCWFNNLTDE 233
KL N++FT EL+ RL T V VN +HPGI+ TN+ LL + F ++ W T
Sbjct: 221 KLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPV 280
Query: 234 DGAQTPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
+GAQT ++LA+S +G++F +C E L+ PK +E + +KLW+ S ++
Sbjct: 281 EGAQTSIYLASSPEVEGVSGRYFGDCKEEELL-PKAMDESVARKLWDISEVMV 332
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 199 bits (485), Expect = 1e-50
Identities = 115/293 (39%), Positives = 165/293 (56%), Gaps = 15/293 (5%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEII------------ 55
M G+ V++TGANSG+G TA +L R GARVI+GCR R +A ++
Sbjct: 41 MHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPE 100
Query: 56 -SVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTV 114
V+ ++ +++DL+SLRSVR F +++++ E L VLINNAG+F TEDG +
Sbjct: 101 PGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQ 160
Query: 115 MQVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNS 174
VN+ G F K S PSRIV VSS +G INF D N + YN Y S
Sbjct: 161 FGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRS 220
Query: 175 KLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNGCS-NLLYRVGFAVLCWFNNLTDE 233
KL N++FT EL+ RL T V VN +HPGI+ TN+ LL + F ++ W T
Sbjct: 221 KLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPV 280
Query: 234 DGAQTPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
+GAQT ++LA+S +G++F +C E L+ PK +E + +KLW+ S ++
Sbjct: 281 EGAQTSIYLASSPEVEGVSGRYFGDCKEEELL-PKAMDESVARKLWDISEVMV 332
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 198 bits (482), Expect = 3e-50
Identities = 111/297 (37%), Positives = 168/297 (56%), Gaps = 5/297 (1%)
Query: 2 CDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNK 61
C ++ G+ VIVTGAN+GIG QTA +LARRG +IL CR +++ A +I T N
Sbjct: 30 CPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNH 89
Query: 62 NVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFG 121
+V + +DL+SL+S+REFA IIE E + +LINNAG+ TEDG + VN+ G
Sbjct: 90 HVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLG 149
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKS-FYNGILTYCNSKLCNLI 180
F K S PSRI+N+SS+ ++ G I+F D N ++ YN YC SKL ++
Sbjct: 150 HFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVL 209
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNI---TNGCSNLLYRVGFAVLCWFNNLTDEDGAQ 237
FT ELS RL+ +GV VNA+HPG+ T + T + + W + E AQ
Sbjct: 210 FTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLVKSPELAAQ 269
Query: 238 TPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLIRFDESSVQ 294
+LA ++ + +GK+F + + +P+ +E + ++LW S +L+ + SV+
Sbjct: 270 PSTYLAVAEELADVSGKYFDGLKQKA-PAPEAEDEEVARRLWAESARLVGLEAPSVR 325
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 195 bits (475), Expect = 2e-49
Identities = 110/297 (37%), Positives = 167/297 (56%), Gaps = 5/297 (1%)
Query: 2 CDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNK 61
C ++ G+ VIVTGAN+GIG QTA +LARRG +IL CR +++ A +I T N
Sbjct: 30 CPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNH 89
Query: 62 NVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFG 121
+V + +DL+SL+S+R FA IIE E + +LINNAG+ TEDG + VN+ G
Sbjct: 90 HVNARHLDLASLKSIRVFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLG 149
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKS-FYNGILTYCNSKLCNLI 180
F K S PSRI+N+SS+ ++ G I+F D N ++ YN YC SKL ++
Sbjct: 150 HFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVL 209
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNI---TNGCSNLLYRVGFAVLCWFNNLTDEDGAQ 237
FT ELS RL+ +GV VNA+HPG+ T + T + + W + E AQ
Sbjct: 210 FTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLVKSPELAAQ 269
Query: 238 TPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLIRFDESSVQ 294
+LA ++ + +GK+F + + +P+ +E + ++LW S +L+ + SV+
Sbjct: 270 PSTYLAVAEELADVSGKYFDGLKQKA-PAPEAEDEEVARRLWAESARLVGLEAPSVR 325
>BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein.
Length = 305
Score = 185 bits (450), Expect = 2e-46
Identities = 108/286 (37%), Positives = 159/286 (55%), Gaps = 17/286 (5%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+G ARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTG-------------ARVYLACRDVEKGELVAKEIQTTTGN 78
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 79 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 138
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
G F K+S PSRIVNV S+ + G I+F + + FYN L YC+SKL N++
Sbjct: 139 GHFLLTHLLLEKLKESAPSRIVNVFSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANIL 198
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPL 240
FT EL+ RL+ +GV +VHPG + + + S R + + +F T + GAQT L
Sbjct: 199 FTQELARRLKGSGVTTYSVHPGTVQSELVRHSS--FMRWMWWLFSFFIK-TPQQGAQTSL 255
Query: 241 HLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLI 286
H A ++ +G F +C + VS + RNE + ++LW+ S L+
Sbjct: 256 HCALTEGLEILSGNHFSDC-HVAWVSAQARNETIARRLWDVSCDLL 300
>AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein.
Length = 377
Score = 172 bits (418), Expect = 1e-42
Identities = 103/286 (36%), Positives = 152/286 (53%), Gaps = 5/286 (1%)
Query: 2 CDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNK 61
C ++ GR +VTGANSGIG TA +LARRGARV+L CRS +RG A ++ + N
Sbjct: 28 CGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNN 87
Query: 62 NVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFG 121
V+F +DL+SL SVR FA + +E L +LI+NAG+ S + T + + +++VN+ G
Sbjct: 88 EVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISSCGR--TREAFNLLLRVNHIG 145
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFK--DDNHKSFYNGILTYCNSKLCNL 179
PF K PSR+V V+S + G ++FK D + + Y ++KL N+
Sbjct: 146 PFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANV 205
Query: 180 IFTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTP 239
+F EL+ +L TGV A HPG + + + R L W GAQTP
Sbjct: 206 LFARELANQLEATGVTCYAAHPGPVNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTP 265
Query: 240 LHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKL 285
L+ A + +G++F NC V P R++ +LWE S +L
Sbjct: 266 LYCALQEGIEPLSGRYFANCHVEE-VPPAARDDRAAHRLWEASKRL 310
>AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing
oxidoreductase isoform FORII protein.
Length = 414
Score = 163 bits (396), Expect = 7e-40
Identities = 107/293 (36%), Positives = 154/293 (52%), Gaps = 13/293 (4%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+ + V
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKV 177
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPF 123
+DL+ LRSV+ FA+ LHVL+ NA F+ S T+DG++T QVN+ G F
Sbjct: 178 EAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHF 237
Query: 124 XXXXXXXXXXKKSQPSRIVNVSSIFNLFGTIN--------FKDDNHKSFYNGILTYCNSK 175
+S P+R++ VSS + F IN + K+ Y +L Y SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSK 297
Query: 176 LCNLIFTIELSERLRDTGVVVNAVHPG-IILTNITNGCSNLLYRVGFAVLCWFNNLTDED 234
LCN++F+ EL RL GV NAVHPG ++ +NI S +Y + F + F +
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHR--SWWVYTLLFTLARPFTKSMQQG 355
Query: 235 GAQTPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLIR 287
A T A ++ G G +F NC + SP+ ++E + LW S +LI+
Sbjct: 356 AATTVYCAAVPELEG-LGGMYFNNCCR-CMPSPEAQSEETARTLWALSERLIQ 406
>AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein.
Length = 414
Score = 163 bits (396), Expect = 7e-40
Identities = 107/293 (36%), Positives = 154/293 (52%), Gaps = 13/293 (4%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+ + V
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKV 177
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPF 123
+DL+ LRSV+ FA+ LHVL+ NA F+ S T+DG++T QVN+ G F
Sbjct: 178 ETMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHF 237
Query: 124 XXXXXXXXXXKKSQPSRIVNVSSIFNLFGTIN--------FKDDNHKSFYNGILTYCNSK 175
+S P+R++ VSS + F IN + K+ Y +L Y SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSATKNDYWAMLAYNRSK 297
Query: 176 LCNLIFTIELSERLRDTGVVVNAVHPG-IILTNITNGCSNLLYRVGFAVLCWFNNLTDED 234
LCN++F+ EL RL GV NAVHPG ++ +NI S +Y + F + F +
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHR--SWWVYTLLFTLARPFTKSMQQG 355
Query: 235 GAQTPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLIR 287
A T A ++ G G +F NC + SP+ ++E + LW S +LI+
Sbjct: 356 AATTVYCAAVPELEG-LGGMYFNNCCR-CMPSPEAQSEETARTLWALSERLIQ 406
>AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing
protein WWOX protein.
Length = 414
Score = 163 bits (396), Expect = 7e-40
Identities = 107/293 (36%), Positives = 154/293 (52%), Gaps = 13/293 (4%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+ + V
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKV 177
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPF 123
+DL+ LRSV+ FA+ LHVL+ NA F+ S T+DG++T QVN+ G F
Sbjct: 178 EAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHF 237
Query: 124 XXXXXXXXXXKKSQPSRIVNVSSIFNLFGTIN--------FKDDNHKSFYNGILTYCNSK 175
+S P+R++ VSS + F IN + K+ Y +L Y SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSK 297
Query: 176 LCNLIFTIELSERLRDTGVVVNAVHPG-IILTNITNGCSNLLYRVGFAVLCWFNNLTDED 234
LCN++F+ EL RL GV NAVHPG ++ +NI S +Y + F + F +
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHR--SWWVYTLLFTLARPFTKSMQQG 355
Query: 235 GAQTPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKLIR 287
A T A ++ G G +F NC + SP+ ++E + LW S +LI+
Sbjct: 356 AATTVYCAAVPELEG-LGGMYFNNCCR-CMPSPEAQSEETARTLWALSERLIQ 406
>BC015582-1|AAH15582.1| 327|Homo sapiens dehydrogenase/reductase
(SDR family) member 13 protein.
Length = 327
Score = 149 bits (361), Expect = 1e-35
Identities = 91/262 (34%), Positives = 137/262 (52%), Gaps = 5/262 (1%)
Query: 26 TAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDLSSLRSVREFAKDIIE 85
TA +LARRGARV+L CRS +RG A ++ + N V+F +DL+SL SVR FA +
Sbjct: 2 TALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDLASLASVRAFATAFLS 61
Query: 86 TENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXXXXXKKSQPSRIVNVS 145
+E L +LI+NAG+ S + T + + +++VN+ GPF K PSR+V V+
Sbjct: 62 SEPRLDILIHNAGISSCGR--TREAFNLLLRVNHIGPFLLTHLLLPCLKACAPSRVVVVA 119
Query: 146 SIFNLFGTINFK--DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGI 203
S + G ++FK D + + Y ++KL N++F EL+ +L TGV A HPG
Sbjct: 120 SAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFARELANQLEATGVTCYAAHPGP 179
Query: 204 ILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPLHLATSDIGGNATGKFFINCSESS 263
+ + + R L W GAQTPL+ A + +G++F NC
Sbjct: 180 VNSELFLRHVPGWLRPLLRPLAWLVLRAPRGGAQTPLYCALQEGIEPLSGRYFANCHVEE 239
Query: 264 LVSPKTRNEVLRKKLWEHSNKL 285
V P R++ +LWE S +L
Sbjct: 240 -VPPAARDDRAAHRLWEASKRL 260
>AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein.
Length = 526
Score = 147 bits (357), Expect = 4e-35
Identities = 96/256 (37%), Positives = 137/256 (53%), Gaps = 12/256 (4%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+ + V
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKV 177
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPF 123
+DL+ LRSV+ FA+ LHVL+ NA F+ S T+DG++T QVN+ G F
Sbjct: 178 ETMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHF 237
Query: 124 XXXXXXXXXXKKSQPSRIVNVSSIFNLFGTIN--------FKDDNHKSFYNGILTYCNSK 175
+S P+R++ VSS + F IN + K+ Y +L Y SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSK 297
Query: 176 LCNLIFTIELSERLRDTGVVVNAVHPG-IILTNITNGCSNLLYRVGFAVLCWFNNLTDED 234
LCN++F+ EL RL GV NAVHPG ++ +NI S +Y + F + F + +
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHR--SWWVYTLLFTLARPFTK-SMQQ 354
Query: 235 GAQTPLHLATSDIGGN 250
GA T ++ GG+
Sbjct: 355 GAATTVYCCCPRTGGS 370
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 147 bits (356), Expect = 5e-35
Identities = 87/249 (34%), Positives = 135/249 (54%), Gaps = 5/249 (2%)
Query: 50 ARDEIISVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTED 109
A +I T N +V + +DL+SL+S+REFA IIE E + +LINNAG+ TED
Sbjct: 7 AAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTED 66
Query: 110 GIDTVMQVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKS-FYNGI 168
G + VN+ G F K S PSRI+N+SS+ ++ G I+F D N ++ YN
Sbjct: 67 GFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTK 126
Query: 169 LTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNI---TNGCSNLLYRVGFAVLC 225
YC SKL ++FT ELS RL+ +GV VNA+HPG+ T + T + +
Sbjct: 127 AAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIF 186
Query: 226 WFNNLTDEDGAQTPLHLATSDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHSNKL 285
W + E AQ +LA ++ + +GK+F + + +P+ +E + ++LW S +L
Sbjct: 187 WLLVKSPELAAQPSTYLAVAEELADVSGKYFDGLKQKA-PAPEAEDEEVARRLWAESARL 245
Query: 286 IRFDESSVQ 294
+ + SV+
Sbjct: 246 VGLEAPSVR 254
>AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein.
Length = 363
Score = 146 bits (353), Expect = 1e-34
Identities = 87/214 (40%), Positives = 120/214 (56%), Gaps = 9/214 (4%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+ + V
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKV 177
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPF 123
+DL+ LRSV+ FA+ LHVL+ NA F+ S T+DG++T QVN+ G F
Sbjct: 178 ETMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHF 237
Query: 124 XXXXXXXXXXKKSQPSRIVNVSSIFNLFGTIN--------FKDDNHKSFYNGILTYCNSK 175
+S P+R++ VSS + F IN + K+ Y +L Y SK
Sbjct: 238 YLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSK 297
Query: 176 LCNLIFTIELSERLRDTGVVVNAVHPG-IILTNI 208
LCN++F+ EL RL GV NAVHPG ++ +NI
Sbjct: 298 LCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNI 331
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 131 bits (316), Expect = 3e-30
Identities = 64/140 (45%), Positives = 88/140 (62%)
Query: 1 MCDQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN 60
+C V + G+VV+VTGAN+GIG +TAK+LA+RGARV L CR V++G EI + T N
Sbjct: 32 VCTSTVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGN 91
Query: 61 KNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYF 120
+ V+ +++DLS +S+R FAK + E LHVLINNAG+ S T DG + + VN+
Sbjct: 92 QQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHL 151
Query: 121 GPFXXXXXXXXXXKKSQPSR 140
G F K+S PSR
Sbjct: 152 GHFLLTHLLLEKLKESAPSR 171
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 128 bits (310), Expect = 2e-29
Identities = 87/278 (31%), Positives = 131/278 (47%), Gaps = 8/278 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ + + + +I T N V F DL
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDL 103
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 104 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 163
Query: 131 XXXKKS----QPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
K+S +R+V VSS + +N D + Y+ Y SKL ++FT L
Sbjct: 164 DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQ 223
Query: 187 ERLRDTG--VVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPLHLAT 244
L G V N V PG++ T++ R+ +L W T ++GA T ++ A
Sbjct: 224 RLLAAEGSHVTANVVDPGVVNTDVYKHVF-WATRLAKKLLGWLLFKTPDEGAWTSIYAAV 282
Query: 245 SDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHS 282
+ G++ N E+ + T N+ L+++LW S
Sbjct: 283 TPELEGVGGRYLYNKKETKSLH-VTYNQKLQQQLWSKS 319
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 128 bits (310), Expect = 2e-29
Identities = 87/278 (31%), Positives = 131/278 (47%), Gaps = 8/278 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ + + + +I T N V F DL
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDL 103
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 104 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 163
Query: 131 XXXKKS----QPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
K+S +R+V VSS + +N D + Y+ Y SKL ++FT L
Sbjct: 164 DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQ 223
Query: 187 ERLRDTG--VVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPLHLAT 244
L G V N V PG++ T++ R+ +L W T ++GA T ++ A
Sbjct: 224 RLLAAEGSHVTANVVDPGVVNTDVYKHVF-WATRLAKKLLGWLLFKTPDEGAWTSIYAAV 282
Query: 245 SDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHS 282
+ G++ N E+ + T N+ L+++LW S
Sbjct: 283 TPELEGVGGRYLYNKKETKSLH-VTYNQKLQQQLWSKS 319
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 128 bits (308), Expect = 3e-29
Identities = 87/278 (31%), Positives = 131/278 (47%), Gaps = 8/278 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ + + + +I T N V F DL
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDL 103
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 104 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 163
Query: 131 XXXKKS----QPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
K+S +R+V VSS + +N D + Y+ Y SKL ++FT L
Sbjct: 164 DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQ 223
Query: 187 ERLRDTG--VVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPLHLAT 244
L G V N V PG++ T++ R+ +L W T ++GA T ++ A
Sbjct: 224 RLLAAEGSHVTANVVDPGVVNTDLYKHVF-WATRLAKKLLGWLLFKTPDEGAWTSIYAAV 282
Query: 245 SDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHS 282
+ G++ N E+ + T N+ L+++LW S
Sbjct: 283 TPELEGVGGRYLYNEKETKSLH-VTYNQKLQQQLWSKS 319
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 128 bits (308), Expect = 3e-29
Identities = 87/278 (31%), Positives = 131/278 (47%), Gaps = 8/278 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ + + + +I T N V F DL
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDL 103
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 104 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 163
Query: 131 XXXKKS----QPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
K+S +R+V VSS + +N D + Y+ Y SKL ++FT L
Sbjct: 164 DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQ 223
Query: 187 ERLRDTG--VVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPLHLAT 244
L G V N V PG++ T++ R+ +L W T ++GA T ++ A
Sbjct: 224 RLLAAEGSHVTANVVDPGVVNTDLYKHVF-WATRLAKKLLGWLLFKTPDEGAWTSIYAAV 282
Query: 245 SDIGGNATGKFFINCSESSLVSPKTRNEVLRKKLWEHS 282
+ G++ N E+ + T N+ L+++LW S
Sbjct: 283 TPELEGVGGRYLYNEKETKSLH-VTYNQKLQQQLWSKS 319
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 113 bits (272), Expect = 7e-25
Identities = 70/204 (34%), Positives = 99/204 (48%), Gaps = 6/204 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ + + + +I T N V F DL
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDL 103
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 104 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 163
Query: 131 XXXKKS----QPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
K+S +R+V VSS + +N D + Y+ Y SKL ++FT L
Sbjct: 164 DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQ 223
Query: 187 ERLRDTG--VVVNAVHPGIILTNI 208
L G V N V PG++ T++
Sbjct: 224 RLLAAEGSHVTANVVDPGVVNTDV 247
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 113 bits (272), Expect = 7e-25
Identities = 70/204 (34%), Positives = 99/204 (48%), Gaps = 6/204 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ + + + +I T N V F DL
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDL 103
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 104 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 163
Query: 131 XXXKKS----QPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
K+S +R+V VSS + +N D + Y+ Y SKL ++FT L
Sbjct: 164 DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQ 223
Query: 187 ERLRDTG--VVVNAVHPGIILTNI 208
L G V N V PG++ T++
Sbjct: 224 RLLAAEGSHVTANVVDPGVVNTDV 247
>BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein.
Length = 312
Score = 112 bits (269), Expect = 2e-24
Identities = 78/256 (30%), Positives = 126/256 (49%), Gaps = 10/256 (3%)
Query: 3 DQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKN 62
D V + GRV +VTG NSGIG TA ++A+RG V L CR AR EII + N+N
Sbjct: 28 DLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQN 87
Query: 63 VVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGP 122
+ +DLS + + +F ++ + E++LHVLINNAG +++ TEDG++ N G
Sbjct: 88 IFLHIVDLSDPKQIWKFVEN-FKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGV 146
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKD-DNHKSFYNGILTYCNSKLCNLIF 181
+ +K R++ VSS L +N D + ++ ++G + Y +K ++
Sbjct: 147 YILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVL 206
Query: 182 TIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPLH 241
T ++ + +++HPG T G + GF ++ GA T L
Sbjct: 207 TERWAQ--GHPAIHFSSMHPG---WADTPGVRQAM--PGFHARFGDRLRSEAQGADTMLW 259
Query: 242 LA-TSDIGGNATGKFF 256
LA +S +G+FF
Sbjct: 260 LALSSAAAAQPSGRFF 275
>AF217490-1|AAF78197.1| 191|Homo sapiens fragile 16D oxido
reductase protein.
Length = 191
Score = 92.3 bits (219), Expect = 2e-18
Identities = 58/150 (38%), Positives = 82/150 (54%), Gaps = 9/150 (6%)
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+DL+ LRSV+ FA+ LHVL+ NA F+ S T+DG++T QVN+ G F
Sbjct: 10 LDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQ 69
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTIN--------FKDDNHKSFYNGILTYCNSKLCNL 179
+S P+R++ VSS + F IN + K+ Y +L Y SKLCN+
Sbjct: 70 LLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNI 129
Query: 180 IFTIELSERLRDTGVVVNAVHPG-IILTNI 208
+F+ EL RL GV NAVHPG ++ +NI
Sbjct: 130 LFSNELHRRLSPRGVTSNAVHPGNMMYSNI 159
>CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 245
Score = 91.1 bits (216), Expect = 4e-18
Identities = 67/204 (32%), Positives = 92/204 (45%), Gaps = 29/204 (14%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ V F DL
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVII-----------------------VEFLYCDL 80
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 81 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 140
Query: 131 XXXKKS----QPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
K+S +R+V VSS + +N D + Y+ Y SKL ++FT L
Sbjct: 141 DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQ 200
Query: 187 ERLRDTG--VVVNAVHPGIILTNI 208
L G V N V PG++ T++
Sbjct: 201 RLLAAEGSHVTANVVDPGVVNTDV 224
>BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 245
Score = 91.1 bits (216), Expect = 4e-18
Identities = 67/204 (32%), Positives = 92/204 (45%), Gaps = 29/204 (14%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ V F DL
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVII-----------------------VEFLYCDL 80
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 81 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 140
Query: 131 XXXKKS----QPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
K+S +R+V VSS + +N D + Y+ Y SKL ++FT L
Sbjct: 141 DTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQ 200
Query: 187 ERLRDTG--VVVNAVHPGIILTNI 208
L G V N V PG++ T++
Sbjct: 201 RLLAAEGSHVTANVVDPGVVNTDV 224
>CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 86.6 bits (205), Expect = 9e-17
Identities = 52/140 (37%), Positives = 71/140 (50%), Gaps = 4/140 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ + + + +I T N V F DL
Sbjct: 121 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDL 180
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 181 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 240
Query: 131 XXXKKS----QPSRIVNVSS 146
K+S +R+V VSS
Sbjct: 241 DTLKESGSPGHSARVVTVSS 260
>BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 86.6 bits (205), Expect = 9e-17
Identities = 52/140 (37%), Positives = 71/140 (50%), Gaps = 4/140 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
RV IVTG GIG+ TAK LAR G VI+ + + + +I T N V F DL
Sbjct: 121 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCDL 180
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXX 130
+S+ S+R+F + + LHVLINNAG+ + T DG + +NY G F
Sbjct: 181 ASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLL 240
Query: 131 XXXKKS----QPSRIVNVSS 146
K+S +R+V VSS
Sbjct: 241 DTLKESGSPGHSARVVTVSS 260
>AL137300-1|CAB70685.1| 204|Homo sapiens hypothetical protein
protein.
Length = 204
Score = 72.5 bits (170), Expect = 2e-12
Identities = 54/195 (27%), Positives = 86/195 (44%), Gaps = 8/195 (4%)
Query: 94 INNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXXXXXXKKS----QPSRIVNVSSIFN 149
INNAG+ + T DG + +NY G F K+S +R+V VSS +
Sbjct: 1 INNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLLLDTLKESGSPGHSARVVTVSSATH 60
Query: 150 LFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTG--VVVNAVHPGIILTN 207
+N D + Y+ Y SKL ++FT L L G V N V PG++ T+
Sbjct: 61 YVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTD 120
Query: 208 ITNGCSNLLYRVGFAVLCWFNNLTDEDGAQTPLHLATSDIGGNATGKFFINCSESSLVSP 267
+ R+ +L W T ++GA T ++ A + G++ N E+ +
Sbjct: 121 LYKHVF-WATRLAKKLLGWLLFKTPDEGAWTSIYAAVTPELEGVGGRYLYNEKETKSLH- 178
Query: 268 KTRNEVLRKKLWEHS 282
T N+ L+++LW S
Sbjct: 179 VTYNQKLQQQLWSKS 193
>AL162377-1|CAI13427.1| 242|Homo sapiens dehydrogenase/reductase
(SDR family) member 12 protein.
Length = 242
Score = 64.5 bits (150), Expect = 4e-10
Identities = 50/199 (25%), Positives = 93/199 (46%), Gaps = 10/199 (5%)
Query: 60 NKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNY 119
++N+ +DLS + + +F ++ + E++LHVLINNAG +++ TEDG++ N
Sbjct: 41 SENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANT 99
Query: 120 FGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKD-DNHKSFYNGILTYCNSKLCN 178
G + +K R++ VSS L +N D + ++ ++G + Y +K
Sbjct: 100 LGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQ 159
Query: 179 LIFTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQT 238
++ T ++ + +++HPG T G + GF ++ GA T
Sbjct: 160 VVLTERWAQ--GHPAIHFSSMHPG---WADTPGVRQAM--PGFHARFGDRLRSEAQGADT 212
Query: 239 PLHLA-TSDIGGNATGKFF 256
L LA +S +G+FF
Sbjct: 213 MLWLALSSAAAAQPSGRFF 231
>AL136525-2|CAH70586.1| 242|Homo sapiens dehydrogenase/reductase
(SDR family) member 12 protein.
Length = 242
Score = 64.5 bits (150), Expect = 4e-10
Identities = 50/199 (25%), Positives = 93/199 (46%), Gaps = 10/199 (5%)
Query: 60 NKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNY 119
++N+ +DLS + + +F ++ + E++LHVLINNAG +++ TEDG++ N
Sbjct: 41 SENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANT 99
Query: 120 FGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKD-DNHKSFYNGILTYCNSKLCN 178
G + +K R++ VSS L +N D + ++ ++G + Y +K
Sbjct: 100 LGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQ 159
Query: 179 LIFTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQT 238
++ T ++ + +++HPG T G + GF ++ GA T
Sbjct: 160 VVLTERWAQ--GHPAIHFSSMHPG---WADTPGVRQAM--PGFHARFGDRLRSEAQGADT 212
Query: 239 PLHLA-TSDIGGNATGKFF 256
L LA +S +G+FF
Sbjct: 213 MLWLALSSAAAAQPSGRFF 231
>AK023701-1|BAB14646.1| 242|Homo sapiens protein ( Homo sapiens
cDNA FLJ13639 fis, clone PLACE1011219, weakly similar to
PROBABLE OXIDOREDUCTASE (EC 1.-.-.-). ).
Length = 242
Score = 64.5 bits (150), Expect = 4e-10
Identities = 50/199 (25%), Positives = 93/199 (46%), Gaps = 10/199 (5%)
Query: 60 NKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNY 119
++N+ +DLS + + +F ++ + E++LHVLINNAG +++ TEDG++ N
Sbjct: 41 SENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANT 99
Query: 120 FGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKD-DNHKSFYNGILTYCNSKLCN 178
G + +K R++ VSS L +N D + ++ ++G + Y +K
Sbjct: 100 LGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQ 159
Query: 179 LIFTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGFAVLCWFNNLTDEDGAQT 238
++ T ++ + +++HPG T G + GF ++ GA T
Sbjct: 160 VVLTERWAQ--GHPAIHFSSMHPG---WADTPGVRQAM--PGFHARFGDRLRSEAQGADT 212
Query: 239 PLHLA-TSDIGGNATGKFF 256
L LA +S +G+FF
Sbjct: 213 MLWLALSSAAAAQPSGRFF 231
>EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NADPH)
3, EC 1.1.1.284. protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3
variant protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbonyl
reductase 3 protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 64.1 bits (149), Expect = 6e-10
Identities = 50/168 (29%), Positives = 80/168 (47%), Gaps = 7/168 (4%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVV 64
+S RV +VTGAN GIG A++L R+ V+L R V RG A ++ +
Sbjct: 1 MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL--QAEGLSPR 58
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGM-FSSEKSYTED-GIDTVMQVNYFGP 122
F Q+D+ L+S+R + + L+VL+NNA + F S+ D + ++ N+F
Sbjct: 59 FHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFAT 118
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILT 170
K R+VN+SS+ L N +D + F++ LT
Sbjct: 119 RNMCNELLPIMKPH--GRVVNISSLQCLRAFENCSEDLQERFHSETLT 164
>BC009825-1|AAH09825.1| 271|Homo sapiens dehydrogenase/reductase
(SDR family) member 12 protein.
Length = 271
Score = 63.3 bits (147), Expect = 1e-09
Identities = 36/144 (25%), Positives = 73/144 (50%), Gaps = 4/144 (2%)
Query: 60 NKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNY 119
++N+ +DLS + + +F ++ + E++LHVLINNAG +++ TEDG++ N
Sbjct: 41 SENIFLHIVDLSDPKQIWKFVENF-KQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANT 99
Query: 120 FGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKD-DNHKSFYNGILTYCNSKLCN 178
G + +K R++ VSS L +N D + ++ ++G + Y +K
Sbjct: 100 LGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQ 159
Query: 179 LIFTIELSERLRDTGVVVNAVHPG 202
++ T ++ + +++HPG
Sbjct: 160 VVLTERWAQ--GHPAIHFSSMHPG 181
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 10/172 (5%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILG-----CRSVDRGTKARDEIISVTNNKNVV 64
GRVV+VTGA +G+G A A RGA V++ + V +G+ A D+++ +
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGK 68
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMF--SSEKSYTEDGIDTVMQVNYFGP 122
+ S+ + K ++ + V++NNAG+ S +++ D + +V+ G
Sbjct: 69 -AVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGS 127
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNS 174
F KK + RI+ SS ++G NF N+ + G+L NS
Sbjct: 128 FQVTRAAWEHMKKQKYGRIIMTSSASGIYG--NFGQANYSAAKLGLLGLANS 177
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 10/172 (5%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILG-----CRSVDRGTKARDEIISVTNNKNVV 64
GRVV+VTGA +G+G A A RGA V++ + V +G+ A D+++ +
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGK 68
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMF--SSEKSYTEDGIDTVMQVNYFGP 122
+ S+ + K ++ + V++NNAG+ S +++ D + +V+ G
Sbjct: 69 -AVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGS 127
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNS 174
F KK + RI+ SS ++G NF N+ + G+L NS
Sbjct: 128 FQVTRAAWEHMKKQKYGRIIMTSSASGIYG--NFGQANYSAAKLGLLGLANS 177
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 62.1 bits (144), Expect = 2e-09
Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 10/172 (5%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILG-----CRSVDRGTKARDEIISVTNNKNVV 64
GRVV+VTGA +G+G A A RGA V++ + V +G+ A D+++ +
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRRRGGK 68
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMF--SSEKSYTEDGIDTVMQVNYFGP 122
+ S+ + K ++ + V++NNAG+ S +++ D + +V+ G
Sbjct: 69 -AVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLRGS 127
Query: 123 FXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNS 174
F KK + RI+ SS ++G NF N+ + G+L NS
Sbjct: 128 FQVTRAAWEHMKKQKYGRIIMTSSASGIYG--NFGQANYSAAKLGLLGLANS 177
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 5/140 (3%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEI---ISVTNNKNVVFK 66
G+V IVTG +GIG K+L G+ V++ R ++R A DE+ + T V+
Sbjct: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG--MFSSEKSYTEDGIDTVMQVNYFGPFX 124
Q ++ + V K ++T +++ L+NN G S + + G V++ N G F
Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137
Query: 125 XXXXXXXXXKKSQPSRIVNV 144
K IVN+
Sbjct: 138 MCKAVYSSWMKEHGGSIVNI 157
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 5/140 (3%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEI---ISVTNNKNVVFK 66
G+V IVTG +GIG K+L G+ V++ R ++R A DE+ + T V+
Sbjct: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG--MFSSEKSYTEDGIDTVMQVNYFGPFX 124
Q ++ + V K ++T +++ L+NN G S + + G V++ N G F
Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137
Query: 125 XXXXXXXXXKKSQPSRIVNV 144
K IVN+
Sbjct: 138 MCKAVYSSWMKEHGGSIVNI 157
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 5/140 (3%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEI---ISVTNNKNVVFK 66
G+V IVTG +GIG K+L G+ V++ R ++R A DE+ + T V+
Sbjct: 37 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 96
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG--MFSSEKSYTEDGIDTVMQVNYFGPFX 124
Q ++ + V K ++T +++ L+NN G S + + G V++ N G F
Sbjct: 97 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 156
Query: 125 XXXXXXXXXKKSQPSRIVNV 144
K IVN+
Sbjct: 157 MCKAVYSSWMKEHGGSIVNI 176
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 61.3 bits (142), Expect = 4e-09
Identities = 38/140 (27%), Positives = 63/140 (45%), Gaps = 5/140 (3%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEI---ISVTNNKNVVFK 66
G+V IVTG +GIG K+L G+ V++ R ++R A DE+ + T V+
Sbjct: 18 GQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG--MFSSEKSYTEDGIDTVMQVNYFGPFX 124
Q ++ + V K ++T +++ L+NN G S + + G V++ N G F
Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFY 137
Query: 125 XXXXXXXXXKKSQPSRIVNV 144
K IVN+
Sbjct: 138 MCKAVYSSWMKEHGGSIVNI 157
>AF325429-1|AAL05450.1| 189|Homo sapiens WW domain-containing
oxidoreductase isoform FORIII protein.
Length = 189
Score = 60.9 bits (141), Expect = 5e-09
Identities = 29/58 (50%), Positives = 37/58 (63%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNK 61
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+ K
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWKTK 175
>AF227528-1|AAF82055.1| 189|Homo sapiens FOR III protein protein.
Length = 189
Score = 60.9 bits (141), Expect = 5e-09
Identities = 29/58 (50%), Positives = 37/58 (63%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNK 61
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+ K
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWKTK 175
>AF187015-1|AAF31694.1| 189|Homo sapiens truncated WW-domain
oxidoreductase protein.
Length = 189
Score = 60.9 bits (141), Expect = 5e-09
Identities = 29/58 (50%), Positives = 37/58 (63%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNK 61
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+ K
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWKTK 175
>BT007445-1|AAP36113.1| 234|Homo sapiens WW domain containing
oxidoreductase protein.
Length = 234
Score = 60.5 bits (140), Expect = 7e-09
Identities = 28/52 (53%), Positives = 36/52 (69%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEII 55
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRIL 169
>BC003184-1|AAH03184.1| 234|Homo sapiens WWOX protein protein.
Length = 234
Score = 60.5 bits (140), Expect = 7e-09
Identities = 28/52 (53%), Positives = 36/52 (69%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEII 55
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRIL 169
>AF395123-1|AAK81727.1| 234|Homo sapiens WWOXdelta6-8 protein.
Length = 234
Score = 60.5 bits (140), Expect = 7e-09
Identities = 28/52 (53%), Positives = 36/52 (69%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEII 55
Q G+VV+VTGANSGIGF+TAK A GA VIL CR++ R ++A I+
Sbjct: 118 QGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRIL 169
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 13/170 (7%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTN--NKNVVFKQID 69
VV VTGA+SGIG + A L++ G ++L R V + + + N K+++ +D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTED-GIDT---VMQVNYFGPFXX 125
L+ S K +++ + +L+NN GM S++S D +D ++++NY G
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGM--SQRSLCMDTSLDVYRKLIELNYLGTVSL 169
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFG---TINFKDDNH--KSFYNGILT 170
+ + +IV V+SI + +I + H + F+NG+ T
Sbjct: 170 TKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRT 219
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 13/170 (7%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTN--NKNVVFKQID 69
VV VTGA+SGIG + A L++ G ++L R V + + + N K+++ +D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTED-GIDT---VMQVNYFGPFXX 125
L+ S K +++ + +L+NN GM S++S D +D ++++NY G
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGM--SQRSLCMDTSLDVYRKLIELNYLGTVSL 169
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFG---TINFKDDNH--KSFYNGILT 170
+ + +IV V+SI + +I + H + F+NG+ T
Sbjct: 170 TKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRT 219
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 13/170 (7%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTN--NKNVVFKQID 69
VV VTGA+SGIG + A L++ G ++L R V + + + N K+++ +D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTED-GIDT---VMQVNYFGPFXX 125
L+ S K +++ + +L+NN GM S++S D +D ++++NY G
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGM--SQRSLCMDTSLDVYRKLIELNYLGTVSL 119
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFG---TINFKDDNH--KSFYNGILT 170
+ + +IV V+SI + +I + H + F+NG+ T
Sbjct: 120 TKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRT 169
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 13/170 (7%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTN--NKNVVFKQID 69
VV VTGA+SGIG + A L++ G ++L R V + + + N K+++ +D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTED-GIDT---VMQVNYFGPFXX 125
L+ S K +++ + +L+NN GM S++S D +D ++++NY G
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGM--SQRSLCMDTSLDVYRKLIELNYLGTVSL 169
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFG---TINFKDDNH--KSFYNGILT 170
+ + +IV V+SI + +I + H + F+NG+ T
Sbjct: 170 TKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRT 219
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 59.7 bits (138), Expect = 1e-08
Identities = 45/170 (26%), Positives = 82/170 (48%), Gaps = 13/170 (7%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTN--NKNVVFKQID 69
VV VTGA+SGIG + A L++ G ++L R V + + + N K+++ +D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTED-GIDT---VMQVNYFGPFXX 125
L+ S K +++ + +L+NN GM S++S D +D ++++NY G
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGM--SQRSLCMDTSLDVYRKLIELNYLGTVSL 119
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFG---TINFKDDNH--KSFYNGILT 170
+ + +IV V+SI + +I + H + F+NG+ T
Sbjct: 120 TKCVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRT 169
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/204 (25%), Positives = 94/204 (46%), Gaps = 23/204 (11%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+V +VTGA GIG A+ L +GA+V L +++ G + + + + +F Q D
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCD 64
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXX 129
++ + +R+ + +++ L +L+NNAG+ ++EK++ + +Q+N
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV-NNEKNW-----EKTLQINLVSVISGTYLG 118
Query: 130 XXXXKKSQPSR---IVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFT--IE 184
K I+N+SS+ L YC SK + FT
Sbjct: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQP------------VYCASKHGIVGFTRSAA 166
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
L+ L ++GV +NA+ PG + T I
Sbjct: 167 LAANLMNSGVRLNAICPGFVNTAI 190
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/204 (25%), Positives = 94/204 (46%), Gaps = 23/204 (11%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+V +VTGA GIG A+ L +GA+V L +++ G + + + + +F Q D
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCD 64
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXX 129
++ + +R+ + +++ L +L+NNAG+ ++EK++ + +Q+N
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV-NNEKNW-----EKTLQINLVSVISGTYLG 118
Query: 130 XXXXKKSQPSR---IVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFT--IE 184
K I+N+SS+ L YC SK + FT
Sbjct: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQP------------VYCASKHGIVGFTRSAA 166
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
L+ L ++GV +NA+ PG + T I
Sbjct: 167 LAANLMNSGVRLNAICPGFVNTAI 190
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/204 (25%), Positives = 94/204 (46%), Gaps = 23/204 (11%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+V +VTGA GIG A+ L +GA+V L +++ G + + + + +F Q D
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXX 129
++ + +R+ + +++ L +L+NNAG+ ++EK++ + +Q+N
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV-NNEKNW-----EKTLQINLVSVISGTYLG 118
Query: 130 XXXXKKSQPSR---IVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFT--IE 184
K I+N+SS+ L YC SK + FT
Sbjct: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQP------------VYCASKHGIVGFTRSAA 166
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
L+ L ++GV +NA+ PG + T I
Sbjct: 167 LAANLMNSGVRLNAICPGFVNTAI 190
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 59.3 bits (137), Expect = 2e-08
Identities = 52/204 (25%), Positives = 94/204 (46%), Gaps = 23/204 (11%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+V +VTGA GIG A+ L +GA+V L +++ G + + + + +F Q D
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQVNYFGPFXXXXXX 129
++ + +R+ + +++ L +L+NNAG+ ++EK++ + +Q+N
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV-NNEKNW-----EKTLQINLVSVISGTYLG 118
Query: 130 XXXXKKSQPSR---IVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFT--IE 184
K I+N+SS+ L YC SK + FT
Sbjct: 119 LDYMSKQNGGEGGIIINMSSLAGLMPVAQQP------------VYCASKHGIVGFTRSAA 166
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
L+ L ++GV +NA+ PG + T I
Sbjct: 167 LAANLMNSGVRLNAICPGFVNTAI 190
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 59.3 bits (137), Expect = 2e-08
Identities = 37/140 (26%), Positives = 62/140 (44%), Gaps = 5/140 (3%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEI---ISVTNNKNVVFK 66
G+V VTG +GIG K+L G+ V++ R ++R A DE+ + T V+
Sbjct: 18 GQVAFVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPI 77
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG--MFSSEKSYTEDGIDTVMQVNYFGPFX 124
Q ++ + V K ++T +++ L+NN G S + + G V++ N G F
Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLTGSFY 137
Query: 125 XXXXXXXXXKKSQPSRIVNV 144
K IVN+
Sbjct: 138 MCKAVYSSWMKEHGGSIVNI 157
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/142 (31%), Positives = 66/142 (46%), Gaps = 7/142 (4%)
Query: 12 VVIVTGANSGIGFQTAKDLARR-GARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
V +VTG N GIG +DL R V+L R V RG A ++ + + F Q+D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQA--EGLSPRFHQLDI 64
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGI--DTVMQVNYFGPFXXXXX 128
L+S+R + + L VL+NNAG+ T I + M+ N+FG
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTE 124
Query: 129 XXXXXKKSQPSRIVNVSSIFNL 150
K R+VNVSSI ++
Sbjct: 125 LLPLIKPQ--GRVVNVSSIMSV 144
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 58.0 bits (134), Expect = 4e-08
Identities = 57/209 (27%), Positives = 95/209 (45%), Gaps = 22/209 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V +TG +SG G A+ L RG RV+ C + + R + + + V +
Sbjct: 30 KYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQ--TSDRLETVTLDVTKM 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFS----SEKSYTEDGIDTVMQVNYFGPFXXX 126
S+ + ++ K+ + + L L+NNAG+ + E TED ++ +++VN G
Sbjct: 88 ESIAAATQWVKEHV-GDRGLWGLVNNAGILTPITLCEWLNTEDSMN-MLKVNLIGVIQVT 145
Query: 127 XXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
++++ RIVNVSSI G + F F G YC SK F+ L
Sbjct: 146 LSMLPLVRRAR-GRIVNVSSI---LGRVAF-------FVGG---YCVSKYGVEAFSDILR 191
Query: 187 ERLRDTGVVVNAVHPGIILTNITNGCSNL 215
++ GV ++ V PG T +TN +L
Sbjct: 192 REIQHFGVKISIVEPGYFRTGMTNMTQSL 220
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 58.0 bits (134), Expect = 4e-08
Identities = 57/209 (27%), Positives = 95/209 (45%), Gaps = 22/209 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V +TG +SG G A+ L RG RV+ C + + R + + + V +
Sbjct: 30 KYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQ--TSDRLETVTLDVTKM 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFS----SEKSYTEDGIDTVMQVNYFGPFXXX 126
S+ + ++ K+ + + L L+NNAG+ + E TED ++ +++VN G
Sbjct: 88 ESIAAATQWVKEHV-GDRGLWGLVNNAGILTPITLCEWLNTEDSMN-MLKVNLIGVIQVT 145
Query: 127 XXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
++++ RIVNVSSI G + F F G YC SK F+ L
Sbjct: 146 LSMLPLVRRAR-GRIVNVSSI---LGRVAF-------FVGG---YCVSKYGVEAFSDILR 191
Query: 187 ERLRDTGVVVNAVHPGIILTNITNGCSNL 215
++ GV ++ V PG T +TN +L
Sbjct: 192 REIQHFGVKISIVEPGYFRTGMTNMTQSL 220
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 58.0 bits (134), Expect = 4e-08
Identities = 57/209 (27%), Positives = 95/209 (45%), Gaps = 22/209 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V +TG +SG G A+ L RG RV+ C + + R + + + V +
Sbjct: 30 KYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQ--TSDRLETVTLDVTKM 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFS----SEKSYTEDGIDTVMQVNYFGPFXXX 126
S+ + ++ K+ + + L L+NNAG+ + E TED ++ +++VN G
Sbjct: 88 ESIAAATQWVKEHV-GDRGLWGLVNNAGILTPITLCEWLNTEDSMN-MLKVNLIGVIQVT 145
Query: 127 XXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELS 186
++++ RIVNVSSI G + F F G YC SK F+ L
Sbjct: 146 LSMLPLVRRAR-GRIVNVSSI---LGRVAF-------FVGG---YCVSKYGVEAFSDILR 191
Query: 187 ERLRDTGVVVNAVHPGIILTNITNGCSNL 215
++ GV ++ V PG T +TN +L
Sbjct: 192 REIQHFGVKISIVEPGYFRTGMTNMTQSL 220
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEI-ISVTNNKNVV 64
+++ G V+VTG +SGIG A + ++GA + L R+ D+ +A+ EI + N+K VV
Sbjct: 28 LALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVV 87
Query: 65 F-KQIDLS-SLRSVREFAKDIIETENELHVLINNAGMFSSEK--SYTEDGIDTVMQVNYF 120
+D+S V K E + +L+N AGM S K + +M +NY
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINF 156
G K+ + RIV VSS G F
Sbjct: 148 GSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGF 183
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEI-ISVTNNKNVV 64
+++ G V+VTG +SGIG A + ++GA + L R+ D+ +A+ EI + N+K VV
Sbjct: 28 LALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVV 87
Query: 65 F-KQIDLS-SLRSVREFAKDIIETENELHVLINNAGMFSSEK--SYTEDGIDTVMQVNYF 120
+D+S V K E + +L+N AGM S K + +M +NY
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINF 156
G K+ + RIV VSS G F
Sbjct: 148 GSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGF 183
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 57.2 bits (132), Expect = 6e-08
Identities = 47/156 (30%), Positives = 72/156 (46%), Gaps = 5/156 (3%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEI-ISVTNNKNVV 64
+++ G V+VTG +SGIG A + ++GA + L R+ D+ +A+ EI + N+K VV
Sbjct: 28 LALPGAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVV 87
Query: 65 F-KQIDLS-SLRSVREFAKDIIETENELHVLINNAGMFSSEK--SYTEDGIDTVMQVNYF 120
+D+S V K E + +L+N AGM S K + +M +NY
Sbjct: 88 LCISVDVSQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYL 147
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINF 156
G K+ + RIV VSS G F
Sbjct: 148 GSVYPSRAVITTMKERRVGRIVFVSSQAGQLGLFGF 183
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 54.4 bits (125), Expect = 5e-07
Identities = 54/204 (26%), Positives = 86/204 (42%), Gaps = 18/204 (8%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK----Q 67
VV++TGA SG+G + AK GA+++L R+ + E+ + K K
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNAGMF--SSEKSYTEDGIDTVMQVNYFGPFXX 125
DL+ ++ A +I++ + +L+NNAG+ + T D VM+ NYFGP
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 173
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
K + IV +SSI +I F+ Y SK F L
Sbjct: 174 TKALLPSMIKRRQGHIVAISSIQGKM-SIPFRS-----------AYAASKHATQAFFDCL 221
Query: 186 SERLRDTGVVVNAVHPGIILTNIT 209
+ + V + PG I TN++
Sbjct: 222 RAEMEQYEIEVTVISPGYIHTNLS 245
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 54.4 bits (125), Expect = 5e-07
Identities = 54/204 (26%), Positives = 86/204 (42%), Gaps = 18/204 (8%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK----Q 67
VV++TGA SG+G + AK GA+++L R+ + E+ + K K
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNAGMF--SSEKSYTEDGIDTVMQVNYFGPFXX 125
DL+ ++ A +I++ + +L+NNAG+ + T D VM+ NYFGP
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 173
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
K + IV +SSI +I F+ Y SK F L
Sbjct: 174 TKALLPSMIKRRQGHIVAISSIQGKM-SIPFRS-----------AYAASKHATQAFFDCL 221
Query: 186 SERLRDTGVVVNAVHPGIILTNIT 209
+ + V + PG I TN++
Sbjct: 222 RAEMEQYEIEVTVISPGYIHTNLS 245
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 54.4 bits (125), Expect = 5e-07
Identities = 54/204 (26%), Positives = 86/204 (42%), Gaps = 18/204 (8%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK----Q 67
VV++TGA SG+G + AK GA+++L R+ + E+ + K K
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNAGMF--SSEKSYTEDGIDTVMQVNYFGPFXX 125
DL+ ++ A +I++ + +L+NNAG+ + T D VM+ NYFGP
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 173
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
K + IV +SSI +I F+ Y SK F L
Sbjct: 174 TKALLPSMIKRRQGHIVAISSIQGKM-SIPFRS-----------AYAASKHATQAFFDCL 221
Query: 186 SERLRDTGVVVNAVHPGIILTNIT 209
+ + V + PG I TN++
Sbjct: 222 RAEMEQYEIEVTVISPGYIHTNLS 245
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 54.4 bits (125), Expect = 5e-07
Identities = 54/204 (26%), Positives = 86/204 (42%), Gaps = 18/204 (8%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK----Q 67
VV++TGA SG+G + AK GA+++L R+ + E+ + K K
Sbjct: 39 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 98
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNAGMF--SSEKSYTEDGIDTVMQVNYFGPFXX 125
DL+ ++ A +I++ + +L+NNAG+ + T D VM+ NYFGP
Sbjct: 99 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 158
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
K + IV +SSI +I F+ Y SK F L
Sbjct: 159 TKALLPSMIKRRQGHIVAISSIQGKM-SIPFRS-----------AYAASKHATQAFFDCL 206
Query: 186 SERLRDTGVVVNAVHPGIILTNIT 209
+ + V + PG I TN++
Sbjct: 207 RAEMEQYEIEVTVISPGYIHTNLS 230
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 54.4 bits (125), Expect = 5e-07
Identities = 54/204 (26%), Positives = 86/204 (42%), Gaps = 18/204 (8%)
Query: 12 VVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK----Q 67
VV++TGA SG+G + AK GA+++L R+ + E+ + K K
Sbjct: 59 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 118
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNAGMF--SSEKSYTEDGIDTVMQVNYFGPFXX 125
DL+ ++ A +I++ + +L+NNAG+ + T D VM+ NYFGP
Sbjct: 119 FDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVAL 178
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
K + IV +SSI +I F+ Y SK F L
Sbjct: 179 TKALLPSMIKRRQGHIVAISSIQGKM-SIPFRS-----------AYAASKHATQAFFDCL 226
Query: 186 SERLRDTGVVVNAVHPGIILTNIT 209
+ + V + PG I TN++
Sbjct: 227 RAEMEQYEIEVTVISPGYIHTNLS 250
>U13395-1|AAA21465.1| 370|Homo sapiens oxidoreductase protein.
Length = 370
Score = 54.0 bits (124), Expect = 6e-07
Identities = 29/78 (37%), Positives = 43/78 (55%)
Query: 46 RGTKARDEIISVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKS 105
R ++A I+ + V +DL+ LRSV+ FA+ LHVL+ NA F+ S
Sbjct: 3 RASEAVSRILEEWHKAKVEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWS 62
Query: 106 YTEDGIDTVMQVNYFGPF 123
T+DG++T QVN+ G F
Sbjct: 63 LTKDGLETTFQVNHLGHF 80
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 54.0 bits (124), Expect = 6e-07
Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 8/143 (5%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG +SG GF AK L +G V GC D+G E+ S+ N+ + Q+++
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL-NSDRLRTVQLNV 114
Query: 71 SSLRSVREFAK----DIIETENELHVLINNAGMFS-SEKSYTE-DGIDTVMQVNYFGPFX 124
S V + + + + E + L+NNAG+ + E +T + V +VN +G
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 125 XXXXXXXXXKKSQPSRIVNVSSI 147
++++ R+VN+SS+
Sbjct: 175 MTKSFLPLIRRAK-GRVVNISSM 196
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 54.0 bits (124), Expect = 6e-07
Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 8/143 (5%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG +SG GF AK L +G V GC D+G E+ S+ N+ + Q+++
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL-NSDRLRTVQLNV 114
Query: 71 SSLRSVREFAK----DIIETENELHVLINNAGMFS-SEKSYTE-DGIDTVMQVNYFGPFX 124
S V + + + + E + L+NNAG+ + E +T + V +VN +G
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 125 XXXXXXXXXKKSQPSRIVNVSSI 147
++++ R+VN+SS+
Sbjct: 175 MTKSFLPLIRRAK-GRVVNISSM 196
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 54.0 bits (124), Expect = 6e-07
Identities = 52/203 (25%), Positives = 87/203 (42%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V +TG +SG G A+ L RG RV+ C + + R + + + V
Sbjct: 30 KYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQ--TSDRLETVTLDVTKT 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
S+ + ++ K+ + + L L+NNAG+ + + T+ T++ VN G
Sbjct: 88 ESVAAAAQWVKECVR-DKGLWGLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVIDVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
+K++ R+VNVSS+ G + S + G YC SK F+ L
Sbjct: 147 SLLPLVRKAR-GRVVNVSSV---MGRV--------SLFGG--GYCISKYGVEAFSDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
L GV V + PG T +T+
Sbjct: 193 ELSYFGVKVAMIEPGYFKTAVTS 215
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 53.6 bits (123), Expect = 8e-07
Identities = 28/97 (28%), Positives = 57/97 (58%), Gaps = 1/97 (1%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+V +VTGA GIG A+ L +GA+V L +++ G + + + + +F Q D
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY 106
++ + +R+ + +++ L +L+NNAG+ ++EK++
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV-NNEKNW 100
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 53.6 bits (123), Expect = 8e-07
Identities = 40/143 (27%), Positives = 71/143 (49%), Gaps = 8/143 (5%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG +SG GF AK L +G V GC D+G E+ S+ N+ + Q+++
Sbjct: 56 KAVLVTGCDSGFGFALAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL-NSDRLRTVQLNV 114
Query: 71 SSLRSVREFAK----DIIETENELHVLINNAGMFS-SEKSYTE-DGIDTVMQVNYFGPFX 124
S V + + + + E + L+NNAG+ + E +T + V +VN +G
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 125 XXXXXXXXXKKSQPSRIVNVSSI 147
++++ R+VN+SS+
Sbjct: 175 MTKSFLPLIRRAK-GRVVNISSM 196
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 53.2 bits (122), Expect = 1e-06
Identities = 54/212 (25%), Positives = 90/212 (42%), Gaps = 24/212 (11%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q++ +V +TG +SG G A L +RG RV+ C T + E + + +
Sbjct: 22 QSLPASNALVFITGCDSGFGRLLALQLDQRGFRVLASCL-----TPSGAEDLQRVASSRL 76
Query: 64 VFKQIDLSSLRSVREFAK--DIIETENELHVLINN---AGMFSSEKSYTEDGIDTVMQVN 118
+D++ +SV++ AK ++ E L L+NN AG+ T D V+ VN
Sbjct: 77 HTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVN 136
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
GP ++++ R++N++S+ NG YC SK
Sbjct: 137 TMGPIGVTLALLPLLQQAR-GRVINITSVLGRLAA------------NG-GGYCVSKFGL 182
Query: 179 LIFTIELSERLRDTGVVVNAVHPGIILTNITN 210
F+ L + G+ V+ V PG T +TN
Sbjct: 183 EAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTN 214
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+VV+VTG GIG + GARV++ C + G +A ++ + VF D
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVI-CDKDESGGRALEQEL-----PGAVFILCD 62
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTE---DGIDTVMQVNYFGPFXXX 126
++ V+ + I L ++NNAG + E G ++++N G +
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 127 XXXXXXXKKSQPSRIVNVSSIFNLFG 152
+KSQ ++N+SS+ G
Sbjct: 123 KLALPYLRKSQ-GNVINISSLVGAIG 147
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+VV+VTG GIG + GARV++ C + G +A ++ + VF D
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVI-CDKDESGGRALEQEL-----PGAVFILCD 62
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTE---DGIDTVMQVNYFGPFXXX 126
++ V+ + I L ++NNAG + E G ++++N G +
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 127 XXXXXXXKKSQPSRIVNVSSIFNLFG 152
+KSQ ++N+SS+ G
Sbjct: 123 KLALPYLRKSQ-GNVINISSLVGAIG 147
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+VV+VTG GIG + GARV++ C + G +A ++ + VF D
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVI-CDKDESGGRALEQEL-----PGAVFILCD 62
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTE---DGIDTVMQVNYFGPFXXX 126
++ V+ + I L ++NNAG + E G ++++N G +
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 127 XXXXXXXKKSQPSRIVNVSSIFNLFG 152
+KSQ ++N+SS+ G
Sbjct: 123 KLALPYLRKSQ-GNVINISSLVGAIG 147
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/146 (25%), Positives = 64/146 (43%), Gaps = 10/146 (6%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+VV+VTG GIG + GARV++ C + G +A ++ + VF D
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVI-CDKDESGGRALEQEL-----PGAVFILCD 62
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTE---DGIDTVMQVNYFGPFXXX 126
++ V+ + I L ++NNAG + E G ++++N G +
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 127 XXXXXXXKKSQPSRIVNVSSIFNLFG 152
+KSQ ++N+SS+ G
Sbjct: 123 KLALPYLRKSQ-GNVINISSLVGAIG 147
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/212 (25%), Positives = 89/212 (41%), Gaps = 24/212 (11%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q++ V +TG +SG G A L +RG RV+ C T + E + + +
Sbjct: 22 QSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCL-----TPSGAEDLQRVASSRL 76
Query: 64 VFKQIDLSSLRSVREFAK--DIIETENELHVLINN---AGMFSSEKSYTEDGIDTVMQVN 118
+D++ +SV++ AK ++ E L L+NN AG+ T D V+ VN
Sbjct: 77 HTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVN 136
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
GP ++++ R++N++S+ NG YC SK
Sbjct: 137 TMGPIGVTLALLPLLQQAR-GRVINITSVLGRLAA------------NG-GGYCVSKFGL 182
Query: 179 LIFTIELSERLRDTGVVVNAVHPGIILTNITN 210
F+ L + G+ V+ V PG T +TN
Sbjct: 183 EAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTN 214
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 52.4 bits (120), Expect = 2e-06
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 25/221 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVIL---GCRSVDRGTKARDEIISVTNNKNV 63
S+ G +V++TGA GIG QT + A+R + ++L R V+ T A + VT + V
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEE-TAAECRKLGVTAHAYV 91
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFG 121
V D S+ + + + ++ +++NNAG ++ ++ T+D I +VN G
Sbjct: 92 V----DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILG 147
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIF 181
F + IV V+S+ G I + ++ YC+SK + F
Sbjct: 148 HFWITKALLPSMMERNHGHIVTVASVCGHEG-IPY-----------LIPYCSSKFAAVGF 195
Query: 182 TIELSERLR---DTGVVVNAVHPGIILTNITNGCSNLLYRV 219
L+ L+ TG+ + + P + T T S L+ V
Sbjct: 196 HRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPV 236
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 52.4 bits (120), Expect = 2e-06
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 25/221 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVIL---GCRSVDRGTKARDEIISVTNNKNV 63
S+ G +V++TGA GIG QT + A+R + ++L R V+ T A + VT + V
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEE-TAAECRKLGVTAHAYV 91
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFG 121
V D S+ + + + ++ +++NNAG ++ ++ T+D I +VN G
Sbjct: 92 V----DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILG 147
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIF 181
F + IV V+S+ G I + ++ YC+SK + F
Sbjct: 148 HFWITKALLPSMMERNHGHIVTVASVCGHEG-IPY-----------LIPYCSSKFAAVGF 195
Query: 182 TIELSERLR---DTGVVVNAVHPGIILTNITNGCSNLLYRV 219
L+ L+ TG+ + + P + T T S L+ V
Sbjct: 196 HRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPV 236
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 52.4 bits (120), Expect = 2e-06
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 25/221 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVIL---GCRSVDRGTKARDEIISVTNNKNV 63
S+ G +V++TGA GIG QT + A+R + ++L R V+ T A + VT + V
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEE-TAAECRKLGVTAHAYV 91
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFG 121
V D S+ + + + ++ +++NNAG ++ ++ T+D I +VN G
Sbjct: 92 V----DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILG 147
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIF 181
F + IV V+S+ G I + ++ YC+SK + F
Sbjct: 148 HFWITKALLPSMMERNHGHIVTVASVCGHEG-IPY-----------LIPYCSSKFAAVGF 195
Query: 182 TIELSERLR---DTGVVVNAVHPGIILTNITNGCSNLLYRV 219
L+ L+ TG+ + + P + T T S L+ V
Sbjct: 196 HRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPV 236
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 52.4 bits (120), Expect = 2e-06
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 25/221 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVIL---GCRSVDRGTKARDEIISVTNNKNV 63
S+ G +V++TGA GIG QT + A+R + ++L R V+ T A + VT + V
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEE-TAAECRKLGVTAHAYV 91
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFG 121
V D S+ + + + ++ +++NNAG ++ ++ T+D I +VN G
Sbjct: 92 V----DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILG 147
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIF 181
F + IV V+S+ G I + ++ YC+SK + F
Sbjct: 148 HFWITKALLPSMMERNHGHIVTVASVCGHEG-IPY-----------LIPYCSSKFAAVGF 195
Query: 182 TIELSERLR---DTGVVVNAVHPGIILTNITNGCSNLLYRV 219
L+ L+ TG+ + + P + T T S L+ V
Sbjct: 196 HRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPV 236
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 52.4 bits (120), Expect = 2e-06
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 25/221 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVIL---GCRSVDRGTKARDEIISVTNNKNV 63
S+ G +V++TGA GIG QT + A+R + ++L R V+ T A + VT + V
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEE-TAAECRKLGVTAHAYV 91
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFG 121
V D S+ + + + ++ +++NNAG ++ ++ T+D I +VN G
Sbjct: 92 V----DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILG 147
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIF 181
F + IV V+S+ G I + ++ YC+SK + F
Sbjct: 148 HFWITKALLPSMMERNHGHIVTVASVCGHEG-IPY-----------LIPYCSSKFAAVGF 195
Query: 182 TIELSERLR---DTGVVVNAVHPGIILTNITNGCSNLLYRV 219
L+ L+ TG+ + + P + T T S L+ V
Sbjct: 196 HRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPV 236
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 52.4 bits (120), Expect = 2e-06
Identities = 54/212 (25%), Positives = 89/212 (41%), Gaps = 24/212 (11%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q++ V +TG +SG G A L +RG RV+ C T + E + + +
Sbjct: 22 QSLPASNAFVFITGCDSGFGRLLALQLDQRGFRVLASCL-----TPSGAEDLQRVASSRL 76
Query: 64 VFKQIDLSSLRSVREFAK--DIIETENELHVLINN---AGMFSSEKSYTEDGIDTVMQVN 118
+D++ +SV++ AK ++ E L L+NN AG+ T D V+ VN
Sbjct: 77 HTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVN 136
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
GP ++++ R++N++S+ NG YC SK
Sbjct: 137 TMGPIGVTLALLPLLQQAR-GRVINITSVLGRLAA------------NG-GGYCVSKFGL 182
Query: 179 LIFTIELSERLRDTGVVVNAVHPGIILTNITN 210
F+ L + G+ V+ V PG T +TN
Sbjct: 183 EAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTN 214
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 52.4 bits (120), Expect = 2e-06
Identities = 56/221 (25%), Positives = 98/221 (44%), Gaps = 25/221 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVIL---GCRSVDRGTKARDEIISVTNNKNV 63
S+ G +V++TGA GIG QT + A+R + ++L R V+ T A + VT + V
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEE-TAAECRKLGVTAHAYV 91
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFG 121
V D S+ + + + ++ +++NNAG ++ ++ T+D I +VN G
Sbjct: 92 V----DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILG 147
Query: 122 PFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIF 181
F + IV V+S+ G I + ++ YC+SK + F
Sbjct: 148 HFWITKALLPSMMERNHGHIVTVASVCGHEG-IPY-----------LIPYCSSKFAAVGF 195
Query: 182 TIELSERLR---DTGVVVNAVHPGIILTNITNGCSNLLYRV 219
L+ L+ TG+ + + P + T T S L+ V
Sbjct: 196 HRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPV 236
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/90 (28%), Positives = 51/90 (56%)
Query: 10 GRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQID 69
G+V +VTGA GIG A+ L +GA+V L +++ G + + + + +F Q D
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCD 64
Query: 70 LSSLRSVREFAKDIIETENELHVLINNAGM 99
++ + +R+ + +++ L +L+NNAG+
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV 94
>BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein.
Length = 341
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 7 protein.
Length = 341
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase type VII protein.
Length = 341
Score = 52.0 bits (119), Expect = 2e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 51.6 bits (118), Expect = 3e-06
Identities = 50/203 (24%), Positives = 88/203 (43%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V +TG +SG G A+ L RG RV+ C + + R + + + V
Sbjct: 30 KYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKGAEQLRGQ--TSDRLETVTLDVTKT 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
S+ + ++ K+ + + L L+NNAG+ + + T+ + T++ VN G
Sbjct: 88 ESVAAAAQWVKECVR-DKGLWGLVNNAGISLPTAPNELLTKQDLLTILDVNLLGVIDVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
++++ R+VNV F++ G + S + G YC SK F+ L
Sbjct: 147 NLLPLVRRAR-GRVVNV---FSVMGRV--------SLFGG--GYCISKYGVEAFSDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
L GV V + PG T +T+
Sbjct: 193 ELSYFGVKVAMIEPGYFKTAVTS 215
>AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid
dehydrogenase protein.
Length = 341
Score = 51.2 bits (117), Expect = 4e-06
Identities = 56/234 (23%), Positives = 92/234 (39%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDRIYLNAGIMPNPQLNIKALLFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protein
protein.
Length = 341
Score = 51.2 bits (117), Expect = 4e-06
Identities = 56/234 (23%), Positives = 91/234 (38%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGFQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/143 (28%), Positives = 69/143 (48%), Gaps = 8/143 (5%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG +SG GF AK L +G V GC D+G E+ S+ N+ + Q+++
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL-NSDRLRTVQLNV 114
Query: 71 SSLRSVREFAKDI-IETENE---LHVLINNAGMFS-SEKSYTE-DGIDTVMQVNYFGPFX 124
V + D E E + L+NNAG+ + E +T + V +VN +G
Sbjct: 115 FRSEEVEKVVGDCPFEPEGPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 125 XXXXXXXXXKKSQPSRIVNVSSI 147
++++ R+VN+SS+
Sbjct: 175 MTKSFLPLIRRAK-GRVVNISSM 196
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 50.8 bits (116), Expect = 6e-06
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 18/203 (8%)
Query: 13 VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDLSS 72
V++TG GIG Q A++ A RGAR I+ ++ K E I + F D+ +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYF-ICDVGN 99
Query: 73 LRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQ---VNYFGPFXXXXXX 129
V + AK + E ++ +L+NNA + KS + D +++ +N G F
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHG-KSLMDSDDDALLKSQHINTLGQFWTTKAF 158
Query: 130 XXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSERL 189
+ Q IV ++S+ L S G + YC SK F L+ L
Sbjct: 159 LPRMLELQNGHIVCLNSVLAL------------SAIPGAIDYCTSKASAFAFMESLTLGL 206
Query: 190 RD-TGVVVNAVHPGIILTNITNG 211
D GV V P T + G
Sbjct: 207 LDCPGVSATTVLPFHTSTEMFQG 229
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 50.8 bits (116), Expect = 6e-06
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 18/203 (8%)
Query: 13 VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDLSS 72
V++TG GIG Q A++ A RGAR I+ ++ K E I + F D+ +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYF-ICDVGN 99
Query: 73 LRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQ---VNYFGPFXXXXXX 129
V + AK + E ++ +L+NNA + KS + D +++ +N G F
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHG-KSLMDSDDDALLKSQHINTLGQFWTTKAF 158
Query: 130 XXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSERL 189
+ Q IV ++S+ L S G + YC SK F L+ L
Sbjct: 159 LPRMLELQNGHIVCLNSVLAL------------SAIPGAIDYCTSKASAFAFMESLTLGL 206
Query: 190 RD-TGVVVNAVHPGIILTNITNG 211
D GV V P T + G
Sbjct: 207 LDCPGVSATTVLPFHTSTEMFQG 229
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 50.8 bits (116), Expect = 6e-06
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 18/203 (8%)
Query: 13 VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDLSS 72
V++TG GIG Q A++ A RGAR I+ ++ K E I + F D+ +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYF-ICDVGN 99
Query: 73 LRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQ---VNYFGPFXXXXXX 129
V + AK + E ++ +L+NNA + KS + D +++ +N G F
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHG-KSLMDSDDDALLKSQHINTLGQFWTTKAF 158
Query: 130 XXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSERL 189
+ Q IV ++S+ L S G + YC SK F L+ L
Sbjct: 159 LPRMLELQNGHIVCLNSVLAL------------SAIPGAIDYCTSKASAFAFMESLTLGL 206
Query: 190 RD-TGVVVNAVHPGIILTNITNG 211
D GV V P T + G
Sbjct: 207 LDCPGVSATTVLPFHTSTEMFQG 229
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 50.8 bits (116), Expect = 6e-06
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 18/203 (8%)
Query: 13 VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDLSS 72
V++TG GIG Q A++ A RGAR I+ ++ K E I + F D+ +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYF-ICDVGN 99
Query: 73 LRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQ---VNYFGPFXXXXXX 129
V + AK + E ++ +L+NNA + KS + D +++ +N G F
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHG-KSLMDSDDDALLKSQHINTLGQFWTTKAF 158
Query: 130 XXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSERL 189
+ Q IV ++S+ L S G + YC SK F L+ L
Sbjct: 159 LPRMLELQNGHIVCLNSVLAL------------SAIPGAIDYCTSKASAFAFMESLTLGL 206
Query: 190 RD-TGVVVNAVHPGIILTNITNG 211
D GV V P T + G
Sbjct: 207 LDCPGVSATTVLPFHTSTEMFQG 229
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 50.8 bits (116), Expect = 6e-06
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 18/203 (8%)
Query: 13 VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDLSS 72
V++TG GIG Q A++ A RGAR I+ ++ K E I + F D+ +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYF-ICDVGN 99
Query: 73 LRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQ---VNYFGPFXXXXXX 129
V + AK + E ++ +L+NNA + KS + D +++ +N G F
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHG-KSLMDSDDDALLKSQHINTLGQFWTTKAF 158
Query: 130 XXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSERL 189
+ Q IV ++S+ L S G + YC SK F L+ L
Sbjct: 159 LPRMLELQNGHIVCLNSVLAL------------SAIPGAIDYCTSKASAFAFMESLTLGL 206
Query: 190 RD-TGVVVNAVHPGIILTNITNG 211
D GV V P T + G
Sbjct: 207 LDCPGVSATTVLPFHTSTEMFQG 229
>AF162767-1|AAF14537.1| 341|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 7 protein.
Length = 341
Score = 50.8 bits (116), Expect = 6e-06
Identities = 55/234 (23%), Positives = 91/234 (38%), Gaps = 36/234 (15%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASPTTAEVTIVPV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAG-----------------------MFSSEKS 105
D+S+L+SV +K++ + L + NAG MFS+ +
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTAEG 122
Query: 106 YTEDG-------IDTVMQVNYFGPFXXXXXXXXXXKKS-QPSRIVNVSSIFNLFGTINFK 157
G + V + N FG F S PS+++ SS + +
Sbjct: 123 LLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFSLE 182
Query: 158 DDNHKSFYNGILTYCNSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNG 211
D H G Y +SK + ++ L+ G+ N PG LTN+T G
Sbjct: 183 DFQHS---KGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYG 233
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 50.8 bits (116), Expect = 6e-06
Identities = 54/203 (26%), Positives = 83/203 (40%), Gaps = 18/203 (8%)
Query: 13 VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDLSS 72
V++TG GIG Q A++ A RGAR I+ ++ K E I + F D+ +
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYF-ICDVGN 99
Query: 73 LRSVREFAKDIIETENELHVLINNAGMFSSEKSYTEDGIDTVMQ---VNYFGPFXXXXXX 129
V + AK + E ++ +L+NNA + KS + D +++ +N G F
Sbjct: 100 REEVYQTAKAVREKVGDITILVNNAAVVHG-KSLMDSDDDALLKSQHINTLGQFWTTKAF 158
Query: 130 XXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSERL 189
+ Q IV ++S+ L S G + YC SK F L+ L
Sbjct: 159 LPRMLELQNGHIVCLNSVLAL------------SAIPGAIDYCTSKASAFAFMESLTLGL 206
Query: 190 RD-TGVVVNAVHPGIILTNITNG 211
D GV V P T + G
Sbjct: 207 LDCPGVSATTVLPFHTSTEMFQG 229
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 50.0 bits (114), Expect = 1e-05
Identities = 50/201 (24%), Positives = 86/201 (42%), Gaps = 21/201 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLA---RRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
R V+++G +SGIG + A LA ++ +V+ R + + + + + + Q
Sbjct: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGK-KETLEAAAGEALGQTLTVAQ 64
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNAGM--FSSEKSYTEDGIDTVMQVNYFGPFXX 125
+D+ S SV + I + E+ VL+NNAGM + + + V N+FG
Sbjct: 65 LDVCSDESVAQCLSCI---QGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRL 121
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
K+ + IV +SS+ L G I F D Y SK F L
Sbjct: 122 VKAVLPGMKRRRQGHIVVISSVMGLQGVI-FND-----------VYAASKFALEGFFESL 169
Query: 186 SERLRDTGVVVNAVHPGIILT 206
+ +L + ++ V PG ++T
Sbjct: 170 AIQLLQFNIFISLVEPGPVVT 190
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 49.2 bits (112), Expect = 2e-05
Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G +V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK + ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 49.2 bits (112), Expect = 2e-05
Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G +V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK + ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 49.2 bits (112), Expect = 2e-05
Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G +V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK + ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 49.2 bits (112), Expect = 2e-05
Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G +V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK + ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 49.2 bits (112), Expect = 2e-05
Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G +V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK + ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 49.2 bits (112), Expect = 2e-05
Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G +V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK + ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 49.2 bits (112), Expect = 2e-05
Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G +V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK + ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 48.8 bits (111), Expect = 2e-05
Identities = 49/203 (24%), Positives = 85/203 (41%), Gaps = 20/203 (9%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
KK+Q R++NVSS+ + G Y SK F L
Sbjct: 147 NMLPLVKKAQ-GRVINVSSVGGRLAIVG----------GG---YTPSKYAVEGFNDSLRR 192
Query: 188 RLRDTGVVVNAVHPGIILTNITN 210
++ GV V+ + PG+ TN+ +
Sbjct: 193 DMKAFGVHVSCIEPGLFKTNLAD 215
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 48.4 bits (110), Expect = 3e-05
Identities = 54/215 (25%), Positives = 91/215 (42%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G +V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK+ ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKNCKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKKMSTSL 233
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 48.0 bits (109), Expect = 4e-05
Identities = 54/215 (25%), Positives = 90/215 (41%), Gaps = 19/215 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V++TGA GIG TA + A+ ++++L + G + K F
Sbjct: 33 SVTGETVLITGAGHGIGRLTAYEFAKLKSKLVLWDIN-KHGLEETAAKCKGLGAKVHTF- 90
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAG-MFSSEKSYTED-GIDTVMQVNYFGPFX 124
+D S+ + AK + ++ +L+NNAG +++S+ T+D I+ +VN F
Sbjct: 91 VVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFW 150
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
K+ IV V+S H S +L YC+SK + F
Sbjct: 151 TTKAFLPAMTKNNHGHIVTVASA-----------AGHVS-VPFLLAYCSSKFAAVGFHKT 198
Query: 185 LSER---LRDTGVVVNAVHPGIILTNITNGCSNLL 216
L++ L+ TGV + P + T S L
Sbjct: 199 LTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 48.0 bits (109), Expect = 4e-05
Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 25/209 (11%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRGTKA-RDEIISVTNNKNV 63
+ +V +VT + GIGF A+ LA+ GA V++ R +VD+ + E +SVT +
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCM 89
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYF 120
V K D L ++ + +L++NA + F S TE+ D + +N
Sbjct: 90 VGKAEDRERL------VATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
P +K +V VSSI + F S YN SK L
Sbjct: 144 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGF------SPYN------VSKTALLG 191
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNIT 209
T L+ L + VN + PG+I T+ +
Sbjct: 192 LTKTLAIELAPRNIRVNCLAPGLIKTSFS 220
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 47.6 bits (108), Expect = 5e-05
Identities = 35/150 (23%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ G V +TGA+ GIG A A+ GA +++ ++ K I + V +
Sbjct: 8 LAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGK 67
Query: 68 -----IDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--TEDGIDTVMQVNYF 120
+D+ + + + I+ + +L+NNA S + +D +M VN
Sbjct: 68 ALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTR 127
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNL 150
G + KKS+ + I+N+S NL
Sbjct: 128 GTYLASKACIPYLKKSKVAHILNISPPLNL 157
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 47.6 bits (108), Expect = 5e-05
Identities = 35/150 (23%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ G V +TGA+ GIG A A+ GA +++ ++ K I + V +
Sbjct: 8 LAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGK 67
Query: 68 -----IDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--TEDGIDTVMQVNYF 120
+D+ + + + I+ + +L+NNA S + +D +M VN
Sbjct: 68 ALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTR 127
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNL 150
G + KKS+ + I+N+S NL
Sbjct: 128 GTYLASKACIPYLKKSKVAHILNISPPLNL 157
>AL162732-2|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 47.6 bits (108), Expect = 5e-05
Identities = 35/150 (23%), Positives = 63/150 (42%), Gaps = 7/150 (4%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ G V +TGA+ GIG A A+ GA +++ ++ K I + V +
Sbjct: 8 LAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGK 67
Query: 68 -----IDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--TEDGIDTVMQVNYF 120
+D+ + + + I+ + +L+NNA S + +D +M VN
Sbjct: 68 ALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTR 127
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNL 150
G + KKS+ + I+N+S NL
Sbjct: 128 GTYLASKACIPYLKKSKVAHILNISPPLNL 157
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 46.8 bits (106), Expect = 9e-05
Identities = 56/209 (26%), Positives = 89/209 (42%), Gaps = 25/209 (11%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRGTKA-RDEIISVTNNKNV 63
+ +V +VT + GIGF A+ LA+ GA V++ R +VD+ + E +SVT
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYF 120
V K D L ++ ++ + +L++NA + F S TE+ D + +N
Sbjct: 72 VGKAEDRERLVAM------AVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVK 125
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
P +K +V VSSI + F S YN SK L
Sbjct: 126 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGF------SPYN------VSKTALLG 173
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNIT 209
T L+ L + VN + PG+I T+ +
Sbjct: 174 LTKTLAIELAPRNIRVNCLAPGLIKTSFS 202
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 46.4 bits (105), Expect = 1e-04
Identities = 56/209 (26%), Positives = 87/209 (41%), Gaps = 25/209 (11%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRGTKA-RDEIISVTNNKNV 63
+ +V +VT + GIGF A+ LA+ GA V++ R +VD+ + E +SVT
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 89
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYF 120
V K D L ++ + +L++NA + F S TE+ D + +N
Sbjct: 90 VGKAEDRERL------VATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
P +K +V VSSI + F S YN SK L
Sbjct: 144 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGF------SPYN------VSKTALLG 191
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNIT 209
T L+ L + VN + PG+I T+ +
Sbjct: 192 LTKTLAIELAPRNIRVNCLAPGLIKTSFS 220
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 46.4 bits (105), Expect = 1e-04
Identities = 56/209 (26%), Positives = 87/209 (41%), Gaps = 25/209 (11%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRGTKA-RDEIISVTNNKNV 63
+ +V +VT + GIGF A+ LA+ GA V++ R +VD+ + E +SVT
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 89
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYF 120
V K D L ++ + +L++NA + F S TE+ D + +N
Sbjct: 90 VGKAEDRERL------VATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
P +K +V VSSI + F S YN SK L
Sbjct: 144 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGF------SPYN------VSKTALLG 191
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNIT 209
T L+ L + VN + PG+I T+ +
Sbjct: 192 LTKTLAIELAPRNIRVNCLAPGLIKTSFS 220
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 46.4 bits (105), Expect = 1e-04
Identities = 56/209 (26%), Positives = 87/209 (41%), Gaps = 25/209 (11%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRGTKA-RDEIISVTNNKNV 63
+ +V +VT + GIGF A+ LA+ GA V++ R +VD+ + E +SVT
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 89
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYF 120
V K D L ++ + +L++NA + F S TE+ D + +N
Sbjct: 90 VGKAEDRERL------VATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
P +K +V VSSI + F S YN SK L
Sbjct: 144 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGF------SPYN------VSKTALLG 191
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNIT 209
T L+ L + VN + PG+I T+ +
Sbjct: 192 LTKTLAIELAPRNIRVNCLAPGLIKTSFS 220
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 46.4 bits (105), Expect = 1e-04
Identities = 56/209 (26%), Positives = 87/209 (41%), Gaps = 25/209 (11%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRGTKA-RDEIISVTNNKNV 63
+ +V +VT + GIGF A+ LA+ GA V++ R +VD+ + E +SVT
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYF 120
V K D L ++ + +L++NA + F S TE+ D + +N
Sbjct: 72 VGKAEDRERL------VATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 125
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLI 180
P +K +V VSSI + F S YN SK L
Sbjct: 126 APALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGF------SPYN------VSKTALLG 173
Query: 181 FTIELSERLRDTGVVVNAVHPGIILTNIT 209
T L+ L + VN + PG+I T+ +
Sbjct: 174 LTKTLAIELAPRNIRVNCLAPGLIKTSFS 202
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 13/151 (8%)
Query: 4 QNVSMVGRV----VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTK-ARDEIISVT 58
+N ++VG + V +TG +SG G AK L RG +V+ C + + K RD +
Sbjct: 15 KNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQ 74
Query: 59 NNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVM 115
V K S+++ ++ +D + E L L+NNAG+ + T+D V+
Sbjct: 75 TTLLDVTKS---ESIKAAAQWVRDKV-GEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVI 130
Query: 116 QVNYFGPFXXXXXXXXXXKKSQPSRIVNVSS 146
VN G K+++ R+VN+SS
Sbjct: 131 NVNLVGLIEVTLHMLPMVKRAR-GRVVNMSS 160
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 13/151 (8%)
Query: 4 QNVSMVGRV----VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTK-ARDEIISVT 58
+N ++VG + V +TG +SG G AK L RG +V+ C + + K RD +
Sbjct: 15 KNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQ 74
Query: 59 NNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVM 115
V K S+++ ++ +D + E L L+NNAG+ + T+D V+
Sbjct: 75 TTLLDVTKS---ESIKAAAQWVRDKV-GEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVI 130
Query: 116 QVNYFGPFXXXXXXXXXXKKSQPSRIVNVSS 146
VN G K+++ R+VN+SS
Sbjct: 131 NVNLVGLIEVTLHMLPMVKRAR-GRVVNMSS 160
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 46.0 bits (104), Expect = 2e-04
Identities = 42/151 (27%), Positives = 70/151 (46%), Gaps = 13/151 (8%)
Query: 4 QNVSMVGRV----VIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTK-ARDEIISVT 58
+N ++VG + V +TG +SG G AK L RG +V+ C + + K RD +
Sbjct: 15 KNCNLVGNLSEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQ 74
Query: 59 NNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVM 115
V K S+++ ++ +D + E L L+NNAG+ + T+D V+
Sbjct: 75 TTLLDVTKS---ESIKAAAQWVRDKV-GEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVI 130
Query: 116 QVNYFGPFXXXXXXXXXXKKSQPSRIVNVSS 146
VN G K+++ R+VN+SS
Sbjct: 131 NVNLVGLIEVTLHMLPMVKRAR-GRVVNMSS 160
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 46.0 bits (104), Expect = 2e-04
Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 7/140 (5%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ + +TG +SG G A+ ++G VI C + T + E + + V+ D
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAE--TSERLRTVLLDVTDP 87
Query: 71 SSLRSVREFAKDIIETENELHVLINNA---GMFSSEKSYTEDGIDTVMQVNYFGPFXXXX 127
+++ ++ K+ + E L LINNA G+ + T + ++VN FG
Sbjct: 88 ENVKRTAQWVKNQV-GEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 128 XXXXXXKKSQPSRIVNVSSI 147
KK+Q R++NVSS+
Sbjct: 147 NMLPLVKKAQ-GRVINVSSV 165
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 7/147 (4%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+G+ ++TGA GIG + +LA+RG V+L R++++ E I T ++V Q
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATE-IERTTGRSVKIIQA 105
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM----FSSEKSYTEDGIDTVMQVNYFGPFX 124
D + + E K+ + E+ +L+NN GM S D I +++ N
Sbjct: 106 DFTK-DDIYEHIKEKL-AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLF 151
+ Q I+N+SS LF
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALF 190
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 7/147 (4%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+G+ ++TGA GIG + +LA+RG V+L R++++ E I T ++V Q
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATE-IERTTGRSVKIIQA 105
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM----FSSEKSYTEDGIDTVMQVNYFGPFX 124
D + + E K+ + E+ +L+NN GM S D I +++ N
Sbjct: 106 DFTK-DDIYEHIKEKL-AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLF 151
+ Q I+N+SS LF
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALF 190
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 7/147 (4%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+G+ ++TGA GIG + +LA+RG V+L R++++ E I T ++V Q
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATE-IERTTGRSVKIIQA 105
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM----FSSEKSYTEDGIDTVMQVNYFGPFX 124
D + + E K+ + E+ +L+NN GM S D I +++ N
Sbjct: 106 DFTK-DDIYEHIKEKL-AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLF 151
+ Q I+N+SS LF
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALF 190
>BC064525-1|AAH64525.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase isoform 1 protein.
Length = 309
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 18/212 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
++ G +V++TGA SG+G A AR G+ ++L + + G + ++ V
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAY 95
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEK--SYTEDGIDTVMQVNYFGPFX 124
D S V A + + ++ +LINNAG+ + +K ++ ++ VN+
Sbjct: 96 TCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW 155
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ +V +SS L G NG+ YC SK F
Sbjct: 156 TYKAFLPAMIANDHGHLVCISSSAGLSGV------------NGLADYCASKFAAFGFAES 203
Query: 185 LSERL---RDTGVVVNAVHPGIILTNITNGCS 213
+ + G+ V P I T + GC+
Sbjct: 204 VFVETFVQKQKGIKTTIVCPFFIKTGMFEGCT 235
>BC037219-1|AAH37219.2| 309|Homo sapiens retinal short chain
dehydrogenase reductase isoform 1 protein.
Length = 309
Score = 45.6 bits (103), Expect = 2e-04
Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 18/212 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
++ G +V++TGA SG+G A AR G+ ++L + + G + ++ V
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAY 95
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEK--SYTEDGIDTVMQVNYFGPFX 124
D S V A + + ++ +LINNAG+ + +K ++ ++ VN+
Sbjct: 96 TCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW 155
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ +V +SS L G NG+ YC SK F
Sbjct: 156 TYKAFLPAMIANDHGHLVCISSSAGLSGV------------NGLADYCASKFAAFGFAES 203
Query: 185 LSERL---RDTGVVVNAVHPGIILTNITNGCS 213
+ + G+ V P I T + GC+
Sbjct: 204 VFVETFVQKQKGIKTTIVCPFFIKTGMFEGCT 235
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 7/147 (4%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+G+ ++TGA GIG + +LA+RG V+L R++++ E I T ++V Q
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATE-IERTTGRSVKIIQA 105
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM----FSSEKSYTEDGIDTVMQVNYFGPFX 124
D + + E K+ + E+ +L+NN GM S D I +++ N
Sbjct: 106 DFTK-DDIYEHIKEKL-AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLF 151
+ Q I+N+SS LF
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALF 190
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 7/147 (4%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+G+ ++TGA GIG + +LA+RG V+L R++++ E I T ++V Q
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATE-IERTTGRSVKIIQA 105
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM----FSSEKSYTEDGIDTVMQVNYFGPFX 124
D + + E K+ + E+ +L+NN GM S D I +++ N
Sbjct: 106 DFTK-DDIYEHIKEKL-AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLF 151
+ Q I+N+SS LF
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALF 190
>AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 111
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM 99
D+S+L+SV +K++ + L + NAG+
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGI 93
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/147 (26%), Positives = 66/147 (44%), Gaps = 7/147 (4%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+G+ ++TGA GIG + +LA+RG V+L R++++ E I T ++V Q
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATE-IERTTGRSVKIIQA 105
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM----FSSEKSYTEDGIDTVMQVNYFGPFX 124
D + + E K+ + E+ +L+NN GM S D I +++ N
Sbjct: 106 DFTK-DDIYEHIKEKL-AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLF 151
+ Q I+N+SS LF
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALF 190
>AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens
cDNA FLJ12867 fis, clone NT2RP2003702, highly similar
to Homo sapiens 17 beta-hydroxysteroid dehydrogenase
type VII ).
Length = 155
Score = 45.6 bits (103), Expect = 2e-04
Identities = 26/91 (28%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM 99
D+S+L+SV +K++ + L + NAG+
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGI 93
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 45.2 bits (102), Expect = 3e-04
Identities = 51/212 (24%), Positives = 87/212 (41%), Gaps = 24/212 (11%)
Query: 4 QNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNV 63
Q++ V +TG +SG G A L ++ RV+ C + G + + S N +
Sbjct: 22 QSLPASNAFVFITGCDSGFGRLLALQLDQKSFRVLASCLT-PSGAEDLQGVASSGFNTTL 80
Query: 64 VFKQIDLSSLRSVREFAK--DIIETENELHVLINN---AGMFSSEKSYTEDGIDTVMQVN 118
+D++ +S ++ AK ++ E L L+NN AG+ T D V+ VN
Sbjct: 81 ----LDITDPQSFQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVN 136
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
GP ++++ R++N++S+ NG YC SK
Sbjct: 137 TMGPIGVTLALLPLLQQAR-GRVINITSVLGRLAA------------NG-GGYCVSKFGL 182
Query: 179 LIFTIELSERLRDTGVVVNAVHPGIILTNITN 210
F+ L + G+ + V PG T +TN
Sbjct: 183 EAFSDSLRRDVAHFGIRESIVEPGFFRTPVTN 214
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 45.2 bits (102), Expect = 3e-04
Identities = 61/234 (26%), Positives = 91/234 (38%), Gaps = 40/234 (17%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILG-------------CRSVDRGTKARD- 52
S+ G+V ++TGA SG+G A + ARR A ++L R + R +A D
Sbjct: 33 SVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADA 92
Query: 53 ---------EIISVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSE 103
E I N V D+ +V A+ + + E+ VL+NNAG+ S
Sbjct: 93 AALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGH 152
Query: 104 K--SYTEDGIDTVMQVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNH 161
++ I+ M VN F + IV V+S LF T +D
Sbjct: 153 HLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVED--- 209
Query: 162 KSFYNGILTYCNSKLCNLIFTIELSERLR---DTGVVVNAVHPGIILTNITNGC 212
YC SK + F LS L+ G+ V P ++ T + GC
Sbjct: 210 ---------YCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGC 254
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 45.2 bits (102), Expect = 3e-04
Identities = 61/234 (26%), Positives = 91/234 (38%), Gaps = 40/234 (17%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILG-------------CRSVDRGTKARD- 52
S+ G+V ++TGA SG+G A + ARR A ++L R + R +A D
Sbjct: 33 SVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADA 92
Query: 53 ---------EIISVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSE 103
E I N V D+ +V A+ + + E+ VL+NNAG+ S
Sbjct: 93 AALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGH 152
Query: 104 K--SYTEDGIDTVMQVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNH 161
++ I+ M VN F + IV V+S LF T +D
Sbjct: 153 HLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVED--- 209
Query: 162 KSFYNGILTYCNSKLCNLIFTIELSERLR---DTGVVVNAVHPGIILTNITNGC 212
YC SK + F LS L+ G+ V P ++ T + GC
Sbjct: 210 ---------YCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGC 254
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 45.2 bits (102), Expect = 3e-04
Identities = 61/234 (26%), Positives = 91/234 (38%), Gaps = 40/234 (17%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILG-------------CRSVDRGTKARD- 52
S+ G+V ++TGA SG+G A + ARR A ++L R + R +A D
Sbjct: 33 SVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADA 92
Query: 53 ---------EIISVTNNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSE 103
E I N V D+ +V A+ + + E+ VL+NNAG+ S
Sbjct: 93 AALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGH 152
Query: 104 K--SYTEDGIDTVMQVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNH 161
++ I+ M VN F + IV V+S LF T +D
Sbjct: 153 HLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVED--- 209
Query: 162 KSFYNGILTYCNSKLCNLIFTIELSERLR---DTGVVVNAVHPGIILTNITNGC 212
YC SK + F LS L+ G+ V P ++ T + GC
Sbjct: 210 ---------YCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGC 254
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 45.2 bits (102), Expect = 3e-04
Identities = 47/212 (22%), Positives = 83/212 (39%), Gaps = 18/212 (8%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
++ G +V++TGA SG+G A AR G+ ++L + + G + ++ V
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVRAY 95
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEK--SYTEDGIDTVMQVNYFGPFX 124
D S V A + + ++ +LINNAG+ + +K ++ ++ VN+
Sbjct: 96 TCDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLW 155
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ +V +SS L G NG+ YC SK F
Sbjct: 156 TYKAFLPAMIANDHGHLVCISSSAGLSGV------------NGLADYCASKFAAFGFAES 203
Query: 185 LSERL---RDTGVVVNAVHPGIILTNITNGCS 213
+ + G+ V P I T + GC+
Sbjct: 204 VFVETFVQKQKGIKTTIVCPFFIKTGMFEGCT 235
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDR-GTKARDEIISVTNNKNVV 64
+ GR +V+GA GIG A++LA RG +IL R+ ++ A+D I+ T
Sbjct: 63 IKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKD--IADTYKVETD 120
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY----TEDGIDTVMQVN 118
D SS R + ++ ++ + ++ +L+NN G+F Y +ED + ++ VN
Sbjct: 121 IIVADFSSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVN 177
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDR-GTKARDEIISVTNNKNVV 64
+ GR +V+GA GIG A++LA RG +IL R+ ++ A+D I+ T
Sbjct: 63 IKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKD--IADTYKVETD 120
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY----TEDGIDTVMQVN 118
D SS R + ++ ++ + ++ +L+NN G+F Y +ED + ++ VN
Sbjct: 121 IIVADFSSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVN 177
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDR-GTKARDEIISVTNNKNVV 64
+ GR +V+GA GIG A++LA RG +IL R+ ++ A+D I+ T
Sbjct: 63 IKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKD--IADTYKVETD 120
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY----TEDGIDTVMQVN 118
D SS R + ++ ++ + ++ +L+NN G+F Y +ED + ++ VN
Sbjct: 121 IIVADFSSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVN 177
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDR-GTKARDEIISVTNNKNVV 64
+ GR +V+GA GIG A++LA RG +IL R+ ++ A+D I+ T
Sbjct: 63 IKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKD--IADTYKVETD 120
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY----TEDGIDTVMQVN 118
D SS R + ++ ++ + ++ +L+NN G+F Y +ED + ++ VN
Sbjct: 121 IIVADFSSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVN 177
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 44.4 bits (100), Expect = 5e-04
Identities = 66/229 (28%), Positives = 98/229 (42%), Gaps = 37/229 (16%)
Query: 3 DQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRG-TKARDEIISVT 58
D+ + RV +VTG+ SGIGF A+ LAR GA V++ R +VDR K + E +SV
Sbjct: 29 DRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVA 88
Query: 59 NNKNVVFKQIDLSSLRSVREFAKDIIETENELHVLINNAG---MFSSEKSYTEDGIDTVM 115
V K D L AK +E + L+ +AG + S +E D ++
Sbjct: 89 GIVCHVGKAEDREQL-----VAK-ALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKIL 142
Query: 116 QVNYFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGIL---TYC 172
VN P +++ ++ VSSI + YN ++ Y
Sbjct: 143 SVNVKSP-ALLLSQLLPYMENRRGAVILVSSI---------------AAYNPVVALGVYN 186
Query: 173 NSKLCNLIFTIELSERLRDTGVVVNAVHPGIILTNITNGCSNLLYRVGF 221
SK L T L+ L + VN V PGII T+ + + R+GF
Sbjct: 187 VSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSK-----VVRIGF 230
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDR-GTKARDEIISVTNNKNVV 64
+ GR +V+GA GIG A++LA RG +IL R+ ++ A+D I+ T
Sbjct: 42 IKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKD--IADTYKVETD 99
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY----TEDGIDTVMQVN 118
D SS R + ++ ++ + ++ +L+NN G+F Y +ED + ++ VN
Sbjct: 100 IIVADFSSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVN 156
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDR-GTKARDEIISVTNNKNVV 64
+ GR +V+GA GIG A++LA RG +IL R+ ++ A+D I+ T
Sbjct: 63 IKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKD--IADTYKVETD 120
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY----TEDGIDTVMQVN 118
D SS R + ++ ++ + ++ +L+NN G+F Y +ED + ++ VN
Sbjct: 121 IIVADFSSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVN 177
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 44.4 bits (100), Expect = 5e-04
Identities = 34/118 (28%), Positives = 60/118 (50%), Gaps = 8/118 (6%)
Query: 6 VSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDR-GTKARDEIISVTNNKNVV 64
+ GR +V+GA GIG A++LA RG +IL R+ ++ A+D I+ T
Sbjct: 42 IKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKD--IADTYKVETD 99
Query: 65 FKQIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY----TEDGIDTVMQVN 118
D SS R + ++ ++ + ++ +L+NN G+F Y +ED + ++ VN
Sbjct: 100 IIVADFSSGREIYLPIREALK-DKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVN 156
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 44.0 bits (99), Expect = 6e-04
Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 3 DQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRG-TKARDEIISV 57
D+ + RV +VTG+ SGIGF A+ LAR GA V++ R +VDR K + E +SV
Sbjct: 29 DRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSV 87
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 44.0 bits (99), Expect = 6e-04
Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 3 DQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRG-TKARDEIISV 57
D+ + RV +VTG+ SGIGF A+ LAR GA V++ R +VDR K + E +SV
Sbjct: 20 DRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSV 78
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 44.0 bits (99), Expect = 6e-04
Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 3 DQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRG-TKARDEIISV 57
D+ + RV +VTG+ SGIGF A+ LAR GA V++ R +VDR K + E +SV
Sbjct: 29 DRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSV 87
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 44.0 bits (99), Expect = 6e-04
Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 3 DQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRG-TKARDEIISV 57
D+ + RV +VTG+ SGIGF A+ LAR GA V++ R +VDR K + E +SV
Sbjct: 29 DRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSV 87
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 44.0 bits (99), Expect = 6e-04
Identities = 26/59 (44%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 3 DQNVSMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRG-TKARDEIISV 57
D+ + RV +VTG+ SGIGF A+ LAR GA V++ R +VDR K + E +SV
Sbjct: 46 DRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSV 104
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S G+V +TG +G+G L+ GA+ ++ R +D ++I S T NK V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNK-VHAI 114
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINN-AGMFSS 102
Q D+ V+ ++I+ +++INN AG F S
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFIS 151
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S G+V +TG +G+G L+ GA+ ++ R +D ++I S T NK V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNK-VHAI 114
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINN-AGMFSS 102
Q D+ V+ ++I+ +++INN AG F S
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFIS 151
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S G+V +TG +G+G L+ GA+ ++ R +D ++I S T NK V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNK-VHAI 114
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINN-AGMFSS 102
Q D+ V+ ++I+ +++INN AG F S
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFIS 151
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S G+V +TG +G+G L+ GA+ ++ R +D ++I S T NK V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNK-VHAI 114
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINN-AGMFSS 102
Q D+ V+ ++I+ +++INN AG F S
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFIS 151
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S G+V +TG +G+G L+ GA+ ++ R +D ++I S T NK V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNK-VHAI 114
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINN-AGMFSS 102
Q D+ V+ ++I+ +++INN AG F S
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFIS 151
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/138 (23%), Positives = 60/138 (43%), Gaps = 3/138 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+V +TG SGIGF+ A+ R G ++ RS+ R A ++ T + + +D+
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL-SMDV 87
Query: 71 SSLRSVREFAKDIIETENELHVLIN-NAGMF-SSEKSYTEDGIDTVMQVNYFGPFXXXXX 128
+ +V ++ + +LIN AG F + + + TVM ++ G F
Sbjct: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147
Query: 129 XXXXXKKSQPSRIVNVSS 146
+ IVN+++
Sbjct: 148 LYEKFFRDHGGVIVNITA 165
>AL023881-2|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/138 (23%), Positives = 60/138 (43%), Gaps = 3/138 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+V +TG SGIGF+ A+ R G ++ RS+ R A ++ T + + +D+
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL-SMDV 87
Query: 71 SSLRSVREFAKDIIETENELHVLIN-NAGMF-SSEKSYTEDGIDTVMQVNYFGPFXXXXX 128
+ +V ++ + +LIN AG F + + + TVM ++ G F
Sbjct: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147
Query: 129 XXXXXKKSQPSRIVNVSS 146
+ IVN+++
Sbjct: 148 LYEKFFRDHGGVIVNITA 165
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/138 (23%), Positives = 60/138 (43%), Gaps = 3/138 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+V +TG SGIGF+ A+ R G ++ RS+ R A ++ T + + +D+
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL-SMDV 87
Query: 71 SSLRSVREFAKDIIETENELHVLIN-NAGMF-SSEKSYTEDGIDTVMQVNYFGPFXXXXX 128
+ +V ++ + +LIN AG F + + + TVM ++ G F
Sbjct: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147
Query: 129 XXXXXKKSQPSRIVNVSS 146
+ IVN+++
Sbjct: 148 LYEKFFRDHGGVIVNITA 165
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S G+V +TG +G+G L+ GA+ ++ R +D ++I S T NK V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNK-VHAI 114
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINN-AGMFSS 102
Q D+ V+ ++I+ +++INN AG F S
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFIS 151
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/138 (23%), Positives = 60/138 (43%), Gaps = 3/138 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+V +TG SGIGF+ A+ R G ++ RS+ R A ++ T + + +D+
Sbjct: 29 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPL-SMDV 87
Query: 71 SSLRSVREFAKDIIETENELHVLIN-NAGMF-SSEKSYTEDGIDTVMQVNYFGPFXXXXX 128
+ +V ++ + +LIN AG F + + + TVM ++ G F
Sbjct: 88 RAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRV 147
Query: 129 XXXXXKKSQPSRIVNVSS 146
+ IVN+++
Sbjct: 148 LYEKFFRDHGGVIVNITA 165
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 2/97 (2%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S G+V +TG +G+G L+ GA+ ++ R +D ++I S T NK V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNK-VHAI 114
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINN-AGMFSS 102
Q D+ V+ ++I+ +++INN AG F S
Sbjct: 115 QCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFIS 151
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
G F +++P + I N F+ G Y SK
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------VGQAAYSASKGGI 175
Query: 179 LIFTIELSERLRDTGVVVNAVHPGI----ILTNITNGCSNLL 216
+ T+ ++ L G+ V + PG+ +LT++ N L
Sbjct: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
G F +++P + I N F+ G Y SK
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------VGQAAYSASKGGI 175
Query: 179 LIFTIELSERLRDTGVVVNAVHPGI----ILTNITNGCSNLL 216
+ T+ ++ L G+ V + PG+ +LT++ N L
Sbjct: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
G F +++P + I N F+ G Y SK
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------VGQAAYSASKGGI 175
Query: 179 LIFTIELSERLRDTGVVVNAVHPGI----ILTNITNGCSNLL 216
+ T+ ++ L G+ V + PG+ +LT++ N L
Sbjct: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
G F +++P + I N F+ G Y SK
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------VGQAAYSASKGGI 175
Query: 179 LIFTIELSERLRDTGVVVNAVHPGI----ILTNITNGCSNLL 216
+ T+ ++ L G+ V + PG+ +LT++ N L
Sbjct: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
G F +++P + I N F+ G Y SK
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------VGQAAYSASKGGI 175
Query: 179 LIFTIELSERLRDTGVVVNAVHPGI----ILTNITNGCSNLL 216
+ T+ ++ L G+ V + PG+ +LT++ N L
Sbjct: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217
>AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase type VII protein.
Length = 223
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGM 99
D+S+L+S +K++ + L + NAG+
Sbjct: 63 DVSNLQSFFRASKELKQRFQRLDRIYLNAGI 93
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
G F +++P + I N F+ G Y SK
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------VGQAAYSASKGGI 175
Query: 179 LIFTIELSERLRDTGVVVNAVHPGI----ILTNITNGCSNLL 216
+ T+ ++ L G+ V + PG+ +LT++ N L
Sbjct: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
G F +++P + I N F+ G Y SK
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------VGQAAYSASKGGI 175
Query: 179 LIFTIELSERLRDTGVVVNAVHPGI----ILTNITNGCSNLL 216
+ T+ ++ L G+ V + PG+ +LT++ N L
Sbjct: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.001
Identities = 52/222 (23%), Positives = 90/222 (40%), Gaps = 23/222 (10%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCN 178
G F +++P + I N F+ G Y SK
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQ------VGQAAYSASKGGI 175
Query: 179 LIFTIELSERLRDTGVVVNAVHPGI----ILTNITNGCSNLL 216
+ T+ ++ L G+ V + PG+ +LT++ N L
Sbjct: 176 VGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFL 217
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 41.5 bits (93), Expect = 0.003
Identities = 51/211 (24%), Positives = 93/211 (44%), Gaps = 26/211 (12%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNK--NVVFKQI 68
+ V +TG +SG G A+ L RG RV+ C + D+G +++ T+++ V
Sbjct: 30 KYVFITGCDSGFGNLLARQLDARGLRVLAACLT-DKGA---EQLRGQTSDRLETVTLDVT 85
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGMFS----SEKSYTEDGIDTVMQVNYFGPFX 124
+ S+ + ++ K+ + + L L+NNAG+ + E TED ++ +++VN G
Sbjct: 86 KMESIAAATQWVKEHV-GDRRLWGLVNNAGILTPITLCEWLNTEDSMN-MLKVNLIGVIQ 143
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
++ +R N + + KS + YC SK F+
Sbjct: 144 VTLSMLPLVRR---ARGKNCQCL----------QHSGKSCFL-CRGYCVSKYGVEAFSDI 189
Query: 185 LSERLRDTGVVVNAVHPGIILTNITNGCSNL 215
L ++ GV ++ V PG T +TN +L
Sbjct: 190 LRREIQHFGVKISIVEPGYFRTGMTNMTQSL 220
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 41.5 bits (93), Expect = 0.003
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
++ G +V++TGA SG+G A AR G+ ++L + + G + ++ V
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAY 95
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEK 104
D S V A + + ++ +LINNAG+ + +K
Sbjct: 96 TCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKK 133
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/89 (28%), Positives = 44/89 (49%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
R+ +VTGA+ GIG A+ L ++G +V+ R+V + E S ++ + DL
Sbjct: 12 RLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDL 71
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGM 99
S+ + I + + + INNAG+
Sbjct: 72 SNEEDILSMFSAIRSQHSGVDICINNAGL 100
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 41.1 bits (92), Expect = 0.005
Identities = 39/147 (26%), Positives = 65/147 (44%), Gaps = 13/147 (8%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCR---SVDRGTKA-RDEIISVTNNKNV 63
+ +V +VT + GIGF A+ LA+ A V++ R +VD+ + E +SVT
Sbjct: 28 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 87
Query: 64 VFKQIDLSSLRSVREFAKDIIETENELHVLINNAGM---FSSEKSYTEDGIDTVMQVNYF 120
V K D L ++ ++ + +L++NA + F S TE+ D + +N
Sbjct: 88 VGKAEDRERLVAM------AVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVK 141
Query: 121 GPFXXXXXXXXXXKKSQPSRIVNVSSI 147
P +K +V VSSI
Sbjct: 142 APALMTKAVVPEMEKRGGGSVVIVSSI 168
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 41.1 bits (92), Expect = 0.005
Identities = 25/89 (28%), Positives = 44/89 (49%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
R+ +VTGA+ GIG A+ L ++G +V+ R+V + E S ++ + DL
Sbjct: 12 RLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDL 71
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGM 99
S+ + I + + + INNAG+
Sbjct: 72 SNEEDILSMFSAIRSQHSGVDICINNAGL 100
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 40.7 bits (91), Expect = 0.006
Identities = 47/202 (23%), Positives = 88/202 (43%), Gaps = 21/202 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+V V G + GIG A+ +AR+G R+ + R+++ A ++ ++ F D+
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAF-SCDV 57
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSS---EKSYTEDGIDTVMQVNYFGPFXXXX 127
+ V+ +++ + ++ L+N AG+ ++ TED + + + N G
Sbjct: 58 AKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMV-SQLHTNLLGSMLTCK 116
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
+ Q IVNV SI L G +G Y SK + F+ L++
Sbjct: 117 AAMRTMIQQQGGSIVNVGSIVGLKGN------------SGQSVYSASKGGLVGFSRALAK 164
Query: 188 RLRDTGVVVNAVHPGIILTNIT 209
+ + VN V PG + T++T
Sbjct: 165 EVARKKIRVNVVAPGFVHTDMT 186
>AL445197-6|CAI15944.1| 84|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 84
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDI 83
D+S+L+SV +K++
Sbjct: 63 DVSNLQSVFRASKEL 77
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 40.3 bits (90), Expect = 0.008
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 21/203 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG + G+G K L G V G + + G A E + T + + Q+D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGA--EELRRTCSPRLSVLQMDI 139
Query: 71 SSLRSVREFAKDI--IETENELHVLINNAGMF---SSEKSYTEDGIDTVMQVNYFGPFXX 125
+ +++ + + + L +INNAG+ + + M VN+FG
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
+KS+ R+VNVSS+ + + +Y +SK +F+ +
Sbjct: 200 TKTFLPLLRKSK-GRLVNVSSM------------GGGAPMERLASYGSSKAAVTMFSSVM 246
Query: 186 SERLRDTGVVVNAVHPGIILTNI 208
L G+ V ++ PG LTNI
Sbjct: 247 RLELSKWGIKVASIQPGGFLTNI 269
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 40.3 bits (90), Expect = 0.008
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 21/203 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG + G+G K L G V G + + G A E + T + + Q+D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGA--EELRRTCSPRLSVLQMDI 139
Query: 71 SSLRSVREFAKDI--IETENELHVLINNAGMF---SSEKSYTEDGIDTVMQVNYFGPFXX 125
+ +++ + + + L +INNAG+ + + M VN+FG
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
+KS+ R+VNVSS+ + + +Y +SK +F+ +
Sbjct: 200 TKTFLPLLRKSK-GRLVNVSSM------------GGGAPMERLASYGSSKAAVTMFSSVM 246
Query: 186 SERLRDTGVVVNAVHPGIILTNI 208
L G+ V ++ PG LTNI
Sbjct: 247 RLELSKWGIKVASIQPGGFLTNI 269
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 40.3 bits (90), Expect = 0.008
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 21/203 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG + G+G K L G V G + + G A E + T + + Q+D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGA--EELRRTCSPRLSVLQMDI 139
Query: 71 SSLRSVREFAKDI--IETENELHVLINNAGMF---SSEKSYTEDGIDTVMQVNYFGPFXX 125
+ +++ + + + L +INNAG+ + + M VN+FG
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
+KS+ R+VNVSS+ + + +Y +SK +F+ +
Sbjct: 200 TKTFLPLLRKSK-GRLVNVSSM------------GGGAPMERLASYGSSKAAVTMFSSVM 246
Query: 186 SERLRDTGVVVNAVHPGIILTNI 208
L G+ V ++ PG LTNI
Sbjct: 247 RLELSKWGIKVASIQPGGFLTNI 269
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 40.3 bits (90), Expect = 0.008
Identities = 47/202 (23%), Positives = 88/202 (43%), Gaps = 21/202 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+V V G + GIG A+ +AR+G R+ + R+++ A ++ ++ F D+
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDL----GGDHLAF-SCDV 57
Query: 71 SSLRSVREFAKDIIETENELHVLINNAGMFSS---EKSYTEDGIDTVMQVNYFGPFXXXX 127
+ V+ +++ + ++ L+N AG+ ++ TED + + + N G
Sbjct: 58 AKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMV-SQLHTNLLGSMLTCK 116
Query: 128 XXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIELSE 187
+ Q IVNV SI L G +G Y SK + F+ L++
Sbjct: 117 AAMRTMIQQQGGSIVNVGSIVGLKGN------------SGQSVYSASKGGLVGFSRALAK 164
Query: 188 RLRDTGVVVNAVHPGIILTNIT 209
+ + VN V PG + T++T
Sbjct: 165 EVARKKIRVNVVAPGFVHTDMT 186
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 40.3 bits (90), Expect = 0.008
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 21/203 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG + G+G K L G V G + + G A E + T + + Q+D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGA--EELRRTCSPRLSVLQMDI 139
Query: 71 SSLRSVREFAKDI--IETENELHVLINNAGMF---SSEKSYTEDGIDTVMQVNYFGPFXX 125
+ +++ + + + L +INNAG+ + + M VN+FG
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
+KS+ R+VNVSS+ + + +Y +SK +F+ +
Sbjct: 200 TKTFLPLLRKSK-GRLVNVSSM------------GGGAPMERLASYGSSKAAVTMFSSVM 246
Query: 186 SERLRDTGVVVNAVHPGIILTNI 208
L G+ V ++ PG LTNI
Sbjct: 247 RLELSKWGIKVASIQPGGFLTNI 269
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 40.3 bits (90), Expect = 0.008
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 21/203 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG + G+G K L G V G + + G A E + T + + Q+D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGA--EELRRTCSPRLSVLQMDI 139
Query: 71 SSLRSVREFAKDI--IETENELHVLINNAGMF---SSEKSYTEDGIDTVMQVNYFGPFXX 125
+ +++ + + + L +INNAG+ + + M VN+FG
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
+KS+ R+VNVSS+ + + +Y +SK +F+ +
Sbjct: 200 TKTFLPLLRKSK-GRLVNVSSM------------GGGAPMERLASYGSSKAAVTMFSSVM 246
Query: 186 SERLRDTGVVVNAVHPGIILTNI 208
L G+ V ++ PG LTNI
Sbjct: 247 RLELSKWGIKVASIQPGGFLTNI 269
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 40.3 bits (90), Expect = 0.008
Identities = 49/203 (24%), Positives = 86/203 (42%), Gaps = 21/203 (10%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQIDL 70
+ V+VTG + G+G K L G V G + + G A E + T + + Q+D+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGA--EELRRTCSPRLSVLQMDI 139
Query: 71 SSLRSVREFAKDI--IETENELHVLINNAGMF---SSEKSYTEDGIDTVMQVNYFGPFXX 125
+ +++ + + + L +INNAG+ + + M VN+FG
Sbjct: 140 TKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEV 199
Query: 126 XXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIEL 185
+KS+ R+VNVSS+ + + +Y +SK +F+ +
Sbjct: 200 TKTFLPLLRKSK-GRLVNVSSM------------GGGAPMERLASYGSSKAAVTMFSSVM 246
Query: 186 SERLRDTGVVVNAVHPGIILTNI 208
L G+ V ++ PG LTNI
Sbjct: 247 RLELSKWGIKVASIQPGGFLTNI 269
>Z97054-9|CAI42652.1| 252|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 252
Score = 39.1 bits (87), Expect = 0.018
Identities = 39/162 (24%), Positives = 70/162 (43%), Gaps = 19/162 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSR------IVNVSSIFNLFGTI 154
G F +++P + I+N +S+ G +
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV 163
>Z97054-7|CAI42651.1| 169|Homo sapiens hydroxyacyl-Coenzyme A
dehydrogenase, type II protein.
Length = 169
Score = 39.1 bits (87), Expect = 0.018
Identities = 39/162 (24%), Positives = 70/162 (43%), Gaps = 19/162 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSR------IVNVSSIFNLFGTI 154
G F +++P + I+N +S+ G +
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV 163
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 39.1 bits (87), Expect = 0.018
Identities = 39/162 (24%), Positives = 70/162 (43%), Gaps = 19/162 (11%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFK 66
S+ G V ++TG SG+G TA+ L +GA +L + G +A+ + + N VF
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAVL-LDLPNSGGEAQAKKL----GNNCVFA 61
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSY--------TEDGIDTVMQVN 118
D++S + V+ + V +N AG+ + K+Y T + V+ VN
Sbjct: 62 PADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVN 121
Query: 119 YFGPFXXXXXXXXXXKKSQPSR------IVNVSSIFNLFGTI 154
G F +++P + I+N +S+ G +
Sbjct: 122 LMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV 163
>BC071987-1|AAH71987.1| 229|Homo sapiens HSD17B7P2 protein
protein.
Length = 229
Score = 38.7 bits (86), Expect = 0.024
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDI 83
D+S+L+S +K++
Sbjct: 63 DVSNLQSFFRASKEL 77
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 38.7 bits (86), Expect = 0.024
Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN-KNVVFK 66
M G+V +VTGA+ GIG A L + GA V + R +D E S+ VV
Sbjct: 5 MNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCD 64
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNA 97
S +RS+ F + E + L VL+NNA
Sbjct: 65 SSQESEVRSL--FEQVDREQQGRLDVLVNNA 93
>BC012536-1|AAH12536.1| 98|Homo sapiens HSD17B12 protein
protein.
Length = 98
Score = 38.7 bits (86), Expect = 0.024
Identities = 19/50 (38%), Positives = 30/50 (60%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVT 58
+G +VTG+ GIG A++LA+ G +V+L RS D+ + EI + T
Sbjct: 49 LGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEISNYT 98
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 38.7 bits (86), Expect = 0.024
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+G +VTG+ GIG A++LA+ G +V+L RS D+ + EI + +
Sbjct: 49 LGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTI-AV 107
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTED 109
D +S + + K + E+ +L+NN GM Y D
Sbjct: 108 DFAS-EDIYDKIKTGL-AGLEIGILVNNVGMSYEYPEYFLD 146
>AY829267-1|AAV87307.1| 229|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 7 form 2 protein.
Length = 229
Score = 38.7 bits (86), Expect = 0.024
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDI 83
D+S+L+S +K++
Sbjct: 63 DVSNLQSFFRASKEL 77
>AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid
dehydrogenase isoform 1 protein.
Length = 264
Score = 38.7 bits (86), Expect = 0.024
Identities = 19/59 (32%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
Query: 7 SMVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVF 65
S+ G +V++TGA GIG QT + A+R + ++L +++ K ++ V NN V+
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLW--DINKVKKEVGDVTIVVNNAGTVY 89
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 38.7 bits (86), Expect = 0.024
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
Query: 9 VGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+G +VTG+ GIG A++LA+ G +V+L RS D+ + EI + +
Sbjct: 49 LGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTI-AV 107
Query: 69 DLSSLRSVREFAKDIIETENELHVLINNAGMFSSEKSYTED 109
D +S + + K + E+ +L+NN GM Y D
Sbjct: 108 DFAS-EDIYDKIKTGL-AGLEIGILVNNVGMSYEYPEYFLD 146
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 38.7 bits (86), Expect = 0.024
Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN-KNVVFK 66
M G+V +VTGA+ GIG A L + GA V + R +D E S+ VV
Sbjct: 5 MNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCD 64
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNA 97
S +RS+ F + E + L VL+NNA
Sbjct: 65 SSQESEVRSL--FEQVDREQQGRLDVLVNNA 93
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 38.7 bits (86), Expect = 0.024
Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 3/91 (3%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNN-KNVVFK 66
M G+V +VTGA+ GIG A L + GA V + R +D E S+ VV
Sbjct: 5 MNGQVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCD 64
Query: 67 QIDLSSLRSVREFAKDIIETENELHVLINNA 97
S +RS+ F + E + L VL+NNA
Sbjct: 65 SSQESEVRSL--FEQVDREQQGRLDVLVNNA 93
>AF165514-1|AAF86644.1| 111|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase type VII isoform protein.
Length = 111
Score = 38.7 bits (86), Expect = 0.024
Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 2/75 (2%)
Query: 11 RVVIVTGANSGIGFQTAKDLARRG--ARVILGCRSVDRGTKARDEIISVTNNKNVVFKQI 68
+VV++TGA+SGIG K L + L CR++ + +++ V Q+
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 69 DLSSLRSVREFAKDI 83
D+S+L+S +K++
Sbjct: 63 DVSNLQSFFRASKEL 77
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 38.7 bits (86), Expect = 0.024
Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 25/204 (12%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ GR V+VTGA GIG T + L GARV+ +V R D ++ V
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVV----AVSRTQADLDSLVRECPGIEPVC-- 58
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNA--GMFSSEKSYTEDGIDTVMQVNYFGPF-X 124
+DL E + + + + +L+NNA + T++ D +VN
Sbjct: 59 VDLGDW----EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQV 114
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ P IVNVSS + N YC++K + T
Sbjct: 115 SQIAARGLIARGVPGAIVNVSSQCSQRAVTNHS------------VYCSTKGALDMLTKV 162
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
++ L + VNAV+P +++T++
Sbjct: 163 MALELGPHKIRVNAVNPTVVMTSM 186
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.032
Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 25/204 (12%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ GR V+VTGA GIG T + L GARV+ +V R D ++ V
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVV----AVSRTQADLDSLVRECPGIEPVC-- 58
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNA--GMFSSEKSYTEDGIDTVMQVNYFGPF-X 124
+DL E + + + + +L+NNA + T++ D +VN
Sbjct: 59 VDLGDW----EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQV 114
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ P IVNVSS + N YC++K + T
Sbjct: 115 SQIVARGLIARGVPGAIVNVSSQCSQRAVTNHS------------VYCSTKGALDMLTKV 162
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
++ L + VNAV+P +++T++
Sbjct: 163 MALELGPHKIRVNAVNPTVVMTSM 186
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 38.3 bits (85), Expect = 0.032
Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 25/204 (12%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ GR V+VTGA GIG T + L GARV+ +V R D ++ V
Sbjct: 4 LAGRRVLVTGAGKGIGRGTVQALHATGARVV----AVSRTQADLDSLVRECPGIEPVC-- 57
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNA--GMFSSEKSYTEDGIDTVMQVNYFGPF-X 124
+DL E + + + + +L+NNA + T++ D +VN
Sbjct: 58 VDLGDW----EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQV 113
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ P IVNVSS + N YC++K + T
Sbjct: 114 SQIVARGLIARGVPGAIVNVSSQCSQRAVTNHS------------VYCSTKGALDMLTKV 161
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
++ L + VNAV+P +++T++
Sbjct: 162 MALELGPHKIRVNAVNPTVVMTSM 185
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.032
Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 25/204 (12%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ GR V+VTGA GIG T + L GARV+ +V R D ++ V
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVV----AVSRTQADLDSLVRECPGIEPVC-- 58
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNA--GMFSSEKSYTEDGIDTVMQVNYFGPF-X 124
+DL E + + + + +L+NNA + T++ D +VN
Sbjct: 59 VDLGDW----EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQV 114
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ P IVNVSS + N YC++K + T
Sbjct: 115 SQIVARGLIARGVPGAIVNVSSQCSQRAVTNHS------------VYCSTKGALDMLTKV 162
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
++ L + VNAV+P +++T++
Sbjct: 163 MALELGPHKIRVNAVNPTVVMTSM 186
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.032
Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 25/204 (12%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ GR V+VTGA GIG T + L GARV+ +V R D ++ V
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVV----AVSRTQADLDSLVRECPGIEPVC-- 58
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNA--GMFSSEKSYTEDGIDTVMQVNYFGPF-X 124
+DL E + + + + +L+NNA + T++ D +VN
Sbjct: 59 VDLGDW----EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQV 114
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ P IVNVSS + N YC++K + T
Sbjct: 115 SQIVARGLIARGVPGAIVNVSSQCSQRAVTNHS------------VYCSTKGALDMLTKV 162
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
++ L + VNAV+P +++T++
Sbjct: 163 MALELGPHKIRVNAVNPTVVMTSM 186
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 38.3 bits (85), Expect = 0.032
Identities = 50/204 (24%), Positives = 82/204 (40%), Gaps = 25/204 (12%)
Query: 8 MVGRVVIVTGANSGIGFQTAKDLARRGARVILGCRSVDRGTKARDEIISVTNNKNVVFKQ 67
+ GR V+VTGA GIG T + L GARV+ +V R D ++ V
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVV----AVSRTQADLDSLVRECPGIEPVC-- 58
Query: 68 IDLSSLRSVREFAKDIIETENELHVLINNA--GMFSSEKSYTEDGIDTVMQVNYFGPF-X 124
+DL E + + + + +L+NNA + T++ D +VN
Sbjct: 59 VDLGDW----EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQV 114
Query: 125 XXXXXXXXXKKSQPSRIVNVSSIFNLFGTINFKDDNHKSFYNGILTYCNSKLCNLIFTIE 184
+ P IVNVSS + N YC++K + T
Sbjct: 115 SQIVARGLIARGVPGAIVNVSSQCSQRAVTNHS------------VYCSTKGALDMLTKV 162
Query: 185 LSERLRDTGVVVNAVHPGIILTNI 208
++ L + VNAV+P +++T++
Sbjct: 163 MALELGPHKIRVNAVNPTVVMTSM 186
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.135 0.393
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 37,077,004
Number of Sequences: 224733
Number of extensions: 1358868
Number of successful extensions: 2959
Number of sequences better than 10.0: 308
Number of HSP's better than 10.0 without gapping: 232
Number of HSP's successfully gapped in prelim test: 76
Number of HSP's that attempted gapping in prelim test: 2464
Number of HSP's gapped (non-prelim): 377
length of query: 295
length of database: 73,234,838
effective HSP length: 89
effective length of query: 206
effective length of database: 53,233,601
effective search space: 10966121806
effective search space used: 10966121806
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 65 (30.3 bits)
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