Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005192-TA|BGIBMGA005192-PA|IPR001236|Lactate/malate
dehydrogenase, IPR010097|Malate dehydrogenase, NAD-dependent,
eukaryotes and gamma proteobacteria
(237 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR536548-1|CAG38785.1| 338|Homo sapiens MDH2 protein. 82 1e-15
BC001917-1|AAH01917.1| 338|Homo sapiens malate dehydrogenase 2,... 82 1e-15
AF047470-1|AAC03787.1| 338|Homo sapiens malate dehydrogenase pr... 82 1e-15
AC005077-1|AAS07425.1| 316|Homo sapiens unknown protein. 82 1e-15
DQ402957-1|ABD77290.1| 305|Homo sapiens mitochondrial malate de... 81 3e-15
BC014079-1|AAH14079.2| 480|Homo sapiens PMPCB protein protein. 31 4.7
BC010398-1|AAH10398.1| 490|Homo sapiens PMPCB protein protein. 31 4.7
AL050216-1|CAB43319.1| 316|Homo sapiens hypothetical protein pr... 31 4.7
U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jag... 30 8.1
U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein. 30 8.1
U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jag... 30 8.1
BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille synd... 30 8.1
BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille synd... 30 8.1
BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille synd... 30 8.1
AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille synd... 30 8.1
AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein J... 30 8.1
AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein. 30 8.1
>CR536548-1|CAG38785.1| 338|Homo sapiens MDH2 protein.
Length = 338
Score = 82.2 bits (194), Expect = 1e-15
Identities = 49/176 (27%), Positives = 94/176 (53%), Gaps = 6/176 (3%)
Query: 3 GVYNKRRVLGVNSVNAMRANQLFSAMTGTDPAARTTPVVCGTGRCTRVPVFS-AGKAGNV 61
GVYN ++ GV +++ +RAN + + G DPA PV+ G T +P+ S +
Sbjct: 159 GVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDF 218
Query: 62 PRSQVECLTRLIREADDIICKVKSNNGQGHLSIGFSTARFVVNIMKGLFQKPTFIDSALV 121
P+ Q+ LT I+EA + K K+ G LS+ ++ ARFV +++ + K ++ + V
Sbjct: 219 PQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFV 278
Query: 122 EQRDPGKCYNMAVCATPVTIGKGGIVEYV-VPQLNEAETKLLEDSKCDLEDMLNLG 176
+ ++ Y +TP+ +GK GI + + + +++ E K++ D+ +L+ + G
Sbjct: 279 KSQETECTY----FSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKG 330
>BC001917-1|AAH01917.1| 338|Homo sapiens malate dehydrogenase 2,
NAD (mitochondrial) protein.
Length = 338
Score = 82.2 bits (194), Expect = 1e-15
Identities = 49/176 (27%), Positives = 94/176 (53%), Gaps = 6/176 (3%)
Query: 3 GVYNKRRVLGVNSVNAMRANQLFSAMTGTDPAARTTPVVCGTGRCTRVPVFS-AGKAGNV 61
GVYN ++ GV +++ +RAN + + G DPA PV+ G T +P+ S +
Sbjct: 159 GVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDF 218
Query: 62 PRSQVECLTRLIREADDIICKVKSNNGQGHLSIGFSTARFVVNIMKGLFQKPTFIDSALV 121
P+ Q+ LT I+EA + K K+ G LS+ ++ ARFV +++ + K ++ + V
Sbjct: 219 PQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFV 278
Query: 122 EQRDPGKCYNMAVCATPVTIGKGGIVEYV-VPQLNEAETKLLEDSKCDLEDMLNLG 176
+ ++ Y +TP+ +GK GI + + + +++ E K++ D+ +L+ + G
Sbjct: 279 KSQETECTY----FSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKG 330
>AF047470-1|AAC03787.1| 338|Homo sapiens malate dehydrogenase
precursor protein.
Length = 338
Score = 82.2 bits (194), Expect = 1e-15
Identities = 49/176 (27%), Positives = 94/176 (53%), Gaps = 6/176 (3%)
Query: 3 GVYNKRRVLGVNSVNAMRANQLFSAMTGTDPAARTTPVVCGTGRCTRVPVFS-AGKAGNV 61
GVYN ++ GV +++ +RAN + + G DPA PV+ G T +P+ S +
Sbjct: 159 GVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDF 218
Query: 62 PRSQVECLTRLIREADDIICKVKSNNGQGHLSIGFSTARFVVNIMKGLFQKPTFIDSALV 121
P+ Q+ LT I+EA + K K+ G LS+ ++ ARFV +++ + K ++ + V
Sbjct: 219 PQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFV 278
Query: 122 EQRDPGKCYNMAVCATPVTIGKGGIVEYV-VPQLNEAETKLLEDSKCDLEDMLNLG 176
+ ++ Y +TP+ +GK GI + + + +++ E K++ D+ +L+ + G
Sbjct: 279 KSQETECTY----FSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKG 330
>AC005077-1|AAS07425.1| 316|Homo sapiens unknown protein.
Length = 316
Score = 82.2 bits (194), Expect = 1e-15
Identities = 49/176 (27%), Positives = 94/176 (53%), Gaps = 6/176 (3%)
Query: 3 GVYNKRRVLGVNSVNAMRANQLFSAMTGTDPAARTTPVVCGTGRCTRVPVFS-AGKAGNV 61
GVYN ++ GV +++ +RAN + + G DPA PV+ G T +P+ S +
Sbjct: 137 GVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDF 196
Query: 62 PRSQVECLTRLIREADDIICKVKSNNGQGHLSIGFSTARFVVNIMKGLFQKPTFIDSALV 121
P+ Q+ LT I+EA + K K+ G LS+ ++ ARFV +++ + K ++ + V
Sbjct: 197 PQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFV 256
Query: 122 EQRDPGKCYNMAVCATPVTIGKGGIVEYV-VPQLNEAETKLLEDSKCDLEDMLNLG 176
+ ++ Y +TP+ +GK GI + + + +++ E K++ D+ +L+ + G
Sbjct: 257 KSQETECTY----FSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKG 308
>DQ402957-1|ABD77290.1| 305|Homo sapiens mitochondrial malate
dehydrogenase 2, NAD protein.
Length = 305
Score = 81.0 bits (191), Expect = 3e-15
Identities = 48/170 (28%), Positives = 92/170 (54%), Gaps = 6/170 (3%)
Query: 3 GVYNKRRVLGVNSVNAMRANQLFSAMTGTDPAARTTPVVCGTGRCTRVPVFS-AGKAGNV 61
GVYN ++ GV +++ +RAN + + G DPA PV+ G T +P+ S +
Sbjct: 138 GVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDF 197
Query: 62 PRSQVECLTRLIREADDIICKVKSNNGQGHLSIGFSTARFVVNIMKGLFQKPTFIDSALV 121
P+ Q+ LT I+EA + K K+ G LS+ ++ ARFV +++ + K ++ + V
Sbjct: 198 PQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFV 257
Query: 122 EQRDPGKCYNMAVCATPVTIGKGGIVEYV-VPQLNEAETKLLEDSKCDLE 170
+ ++ Y +TP+ +GK GI + + + +++ E K++ D+ +L+
Sbjct: 258 KSQETECTY----FSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELK 303
>BC014079-1|AAH14079.2| 480|Homo sapiens PMPCB protein protein.
Length = 480
Score = 30.7 bits (66), Expect = 4.7
Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 140 TIGKGGIVEYVVPQLNEAETKLLEDSKCDLEDMLNLGRCYAVGDEYCIHSCKCPAPPSCK 199
+I + +V+Y+ L +++L+L + + GD C H + PA P CK
Sbjct: 211 SISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAK-FHFGDSLCTHKGEIPALPPCK 269
>BC010398-1|AAH10398.1| 490|Homo sapiens PMPCB protein protein.
Length = 490
Score = 30.7 bits (66), Expect = 4.7
Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 140 TIGKGGIVEYVVPQLNEAETKLLEDSKCDLEDMLNLGRCYAVGDEYCIHSCKCPAPPSCK 199
+I + +V+Y+ L +++L+L + + GD C H + PA P CK
Sbjct: 220 SISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAK-FHFGDSLCTHKGEIPALPPCK 278
>AL050216-1|CAB43319.1| 316|Homo sapiens hypothetical protein
protein.
Length = 316
Score = 30.7 bits (66), Expect = 4.7
Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 1/60 (1%)
Query: 140 TIGKGGIVEYVVPQLNEAETKLLEDSKCDLEDMLNLGRCYAVGDEYCIHSCKCPAPPSCK 199
+I + +V+Y+ L +++L+L + + GD C H + PA P CK
Sbjct: 47 SISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAK-FHFGDSLCTHKGEIPALPPCK 105
>U77720-1|AAC51323.1| 1214|Homo sapiens transmembrane protein Jagged
protein.
Length = 1214
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 693 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 736
>U73936-1|AAC52020.1| 1218|Homo sapiens Jagged 1 protein.
Length = 1218
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 749
>U61276-1|AAB39007.1| 1218|Homo sapiens transmembrane protein Jagged
1 protein.
Length = 1218
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 749
>BC126207-1|AAI26208.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 749
>BC126205-1|AAI26206.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 749
>BC098393-1|AAH98393.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 749
>AL035456-3|CAC07198.1| 1218|Homo sapiens jagged 1 (Alagille
syndrome) protein.
Length = 1218
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 749
>AF028593-1|AAB84053.1| 1218|Homo sapiens transmembrane protein
Jagged 1 protein.
Length = 1218
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 749
>AF003837-1|AAC51731.1| 1218|Homo sapiens Jagged1 protein.
Length = 1218
Score = 29.9 bits (64), Expect = 8.1
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 6/47 (12%)
Query: 164 DSKCDLEDMLNLGRCYAVGDEYCIHSCKCPA---PPSCKTSRNNLIL 207
DS+CD N G CY GD + C CP +C +RN+ L
Sbjct: 706 DSQCDEATCNNGGTCYDEGDAF---KCMCPGGWEGTTCNIARNSSCL 749
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.321 0.135 0.411
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 34,512,979
Number of Sequences: 224733
Number of extensions: 1374999
Number of successful extensions: 2342
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2337
Number of HSP's gapped (non-prelim): 17
length of query: 237
length of database: 73,234,838
effective HSP length: 88
effective length of query: 149
effective length of database: 53,458,334
effective search space: 7965291766
effective search space used: 7965291766
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 64 (29.9 bits)
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