Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005170-TA|BGIBMGA005170-PA|IPR002110|Ankyrin,
IPR005821|Ion transport
(746 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 169 3e-41
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 169 3e-41
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 169 3e-41
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 169 3e-41
U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein. 169 4e-41
AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 169 4e-41
AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 169 4e-41
AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1 var... 160 1e-38
BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein. 157 2e-37
BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein. 157 2e-37
BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein. 157 2e-37
AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens ... 157 2e-37
AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein. 157 2e-37
BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein. 155 5e-37
AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein. 155 5e-37
AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens ... 153 2e-36
X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2... 152 5e-36
X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for ... 152 5e-36
U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein. 152 5e-36
M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein. 152 5e-36
AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 var... 152 5e-36
Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein. 151 9e-36
X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein. 151 9e-36
BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein pr... 151 9e-36
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 151 1e-35
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 151 1e-35
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 151 1e-35
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 149 3e-35
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 149 3e-35
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 149 3e-35
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 149 3e-35
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 149 4e-35
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 146 2e-34
BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein. 140 1e-32
AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens ... 134 1e-30
BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein pr... 132 3e-30
BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein. 131 8e-30
AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein. 131 8e-30
BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein. 131 1e-29
BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein. 131 1e-29
AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined b... 131 1e-29
AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein. 131 1e-29
AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens ... 128 5e-29
BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein. 127 2e-28
AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein p... 124 9e-28
BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH d... 123 2e-27
BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein. 123 2e-27
BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH d... 123 2e-27
BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein. 123 2e-27
BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH d... 123 2e-27
BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH d... 123 2e-27
AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein. 123 2e-27
AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens ... 123 2e-27
AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeat... 123 2e-27
AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeat... 123 2e-27
AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein. 123 2e-27
AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein pr... 121 1e-26
AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens ... 121 1e-26
AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein pr... 121 1e-26
AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6... 120 1e-26
AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein pr... 120 1e-26
AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6... 120 1e-26
BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6... 120 2e-26
AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein. 120 2e-26
CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein. 120 2e-26
BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH d... 120 2e-26
AL365356-2|CAH72614.1| 278|Homo sapiens ankyrin repeat and SOCS... 120 2e-26
Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein prot... 119 3e-26
AF403031-1|AAL57350.1| 286|Homo sapiens ankyrin repeat domain-c... 118 8e-26
BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein. 117 1e-25
AK023196-1|BAB14456.1| 278|Homo sapiens ARPP-19) mRNA. protein. 117 1e-25
AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein. 117 1e-25
BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein. 116 2e-25
BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a pro... 116 2e-25
BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin pro... 116 2e-25
AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein. 116 2e-25
AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein. 116 2e-25
AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein. 116 2e-25
AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein. 116 2e-25
AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein. 116 2e-25
AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein. 116 2e-25
AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein altern... 116 2e-25
AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein. 116 2e-25
AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein. 116 2e-25
AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog p... 116 2e-25
AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase, TRF1-interac... 113 2e-24
AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein. 113 2e-24
AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein. 113 2e-24
AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein. 113 2e-24
AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein. 113 2e-24
AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related prote... 113 2e-24
AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein ... 113 2e-24
BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein. 113 3e-24
AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone met... 113 3e-24
AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lys... 113 3e-24
AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lys... 113 3e-24
AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein. 113 3e-24
AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein. 113 3e-24
BC126351-1|AAI26352.1| 467|Homo sapiens ASB10 protein protein. 112 4e-24
AK125565-1|BAC86204.1| 452|Homo sapiens protein ( Homo sapiens ... 112 4e-24
AF417920-1|AAL59159.1| 429|Homo sapiens ASB-10 protein. 112 4e-24
AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens ... 112 5e-24
AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein. 111 9e-24
X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein. 110 2e-23
BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lys... 110 2e-23
BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lys... 110 2e-23
BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase, TRF1-interac... 110 2e-23
BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein. 110 2e-23
BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein. 110 2e-23
BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein. 110 2e-23
BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein. 110 2e-23
BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein. 110 2e-23
AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated transc... 110 2e-23
AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated transc... 110 2e-23
AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic histone-ly... 110 2e-23
AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic histone-ly... 110 2e-23
AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic histone-ly... 110 2e-23
AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic histone-ly... 110 2e-23
AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic histone-ly... 110 2e-23
AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic histone-ly... 110 2e-23
AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic histone-ly... 110 2e-23
AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic histone-ly... 110 2e-23
AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein. 110 2e-23
AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein. 110 2e-23
AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting ankyri... 110 2e-23
AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting ankyri... 110 2e-23
AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase, TRF1-interac... 110 2e-23
BC131801-1|AAI31802.1| 567|Homo sapiens protein phosphatase 1, ... 107 1e-22
AL121889-1|CAI19080.1| 567|Homo sapiens protein phosphatase 1, ... 107 1e-22
AL031657-1|CAI20058.1| 567|Homo sapiens protein phosphatase 1, ... 107 1e-22
AF362910-1|AAK52796.1| 567|Homo sapiens CAAX box protein TIMAP ... 107 1e-22
AB020630-1|BAA74846.2| 578|Homo sapiens KIAA0823 protein protein. 107 1e-22
BC065710-1|AAH65710.1| 329|Homo sapiens ankyrin repeat and SOCS... 107 1e-22
AY057053-1|AAL18248.1| 329|Homo sapiens SOCS box protein ASB-5 ... 107 1e-22
AK098693-1|BAC05382.1| 276|Homo sapiens protein ( Homo sapiens ... 107 1e-22
AK096441-1|BAC04791.1| 329|Homo sapiens protein ( Homo sapiens ... 107 1e-22
BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein. 107 2e-22
AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2 (Dro... 107 2e-22
AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2 (Dro... 107 2e-22
AL691432-2|CAM12831.1| 999|Homo sapiens mindbomb homolog 2 (Dro... 107 2e-22
AL691432-1|CAM12830.1| 948|Homo sapiens mindbomb homolog 2 (Dro... 107 2e-22
AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens ... 107 2e-22
AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens ... 107 2e-22
AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens ... 107 2e-22
AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens ... 107 2e-22
AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens ... 107 2e-22
AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens ... 107 2e-22
AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activatin... 107 2e-22
AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma prot... 107 2e-22
AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein. 107 2e-22
AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha prot... 107 2e-22
AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein. 107 2e-22
BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein. 105 4e-22
D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein. 105 6e-22
BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and ster... 105 6e-22
BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for IM... 105 6e-22
AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and ster... 105 6e-22
AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and ster... 105 6e-22
AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and ster... 105 6e-22
AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens ... 105 6e-22
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 105 8e-22
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 105 8e-22
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 105 8e-22
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 105 8e-22
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 105 8e-22
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 105 8e-22
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 105 8e-22
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 105 8e-22
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 105 8e-22
BC103875-1|AAI03876.1| 323|Homo sapiens ankyrin repeat and SOCS... 104 1e-21
BC103874-1|AAI03875.1| 323|Homo sapiens ankyrin repeat and SOCS... 104 1e-21
BC069340-1|AAH69340.1| 323|Homo sapiens ankyrin repeat and SOCS... 104 1e-21
AF425642-1|AAL60519.1| 323|Homo sapiens ankyrin repeat domain-c... 104 1e-21
BC075088-1|AAH75088.1| 453|Homo sapiens ankyrin repeat and SOCS... 103 3e-21
AK054727-1|BAB70800.1| 453|Homo sapiens protein ( Homo sapiens ... 103 3e-21
BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 102 5e-21
BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 102 5e-21
BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein. 102 5e-21
BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein. 102 5e-21
BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein. 102 5e-21
AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein. 102 5e-21
AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein. 102 5e-21
AL158217-11|CAI22163.1| 854|Homo sapiens espin protein. 102 5e-21
AL031848-3|CAI19773.1| 854|Homo sapiens espin protein. 102 5e-21
BX005460-4|CAM26150.1| 297|Homo sapiens euchromatic histone-lys... 101 9e-21
BT006845-1|AAP35491.1| 528|Homo sapiens protein phosphatase 1, ... 101 9e-21
BC053506-1|AAH53506.1| 528|Homo sapiens protein phosphatase 1, ... 101 9e-21
BC049841-1|AAH49841.1| 528|Homo sapiens protein phosphatase 1, ... 101 9e-21
BC007854-1|AAH07854.1| 528|Homo sapiens protein phosphatase 1, ... 101 9e-21
AL671762-12|CAI18225.2| 297|Homo sapiens euchromatic histone-ly... 101 9e-21
AL662834-23|CAM24991.1| 297|Homo sapiens euchromatic histone-ly... 101 9e-21
AF403034-1|AAL57353.1| 253|Homo sapiens ankyrin repeat domain-c... 101 9e-21
AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated transc... 101 9e-21
BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 3... 100 2e-20
BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 3... 100 2e-20
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 100 2e-20
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 100 2e-20
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 100 2e-20
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 100 2e-20
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 100 2e-20
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 100 2e-20
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 100 2e-20
BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS... 100 2e-20
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 100 2e-20
AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens ... 100 2e-20
AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containi... 100 2e-20
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 100 2e-20
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 100 2e-20
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 100 2e-20
AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS... 99 3e-20
AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS... 99 3e-20
AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens ... 99 3e-20
BX537853-1|CAD97861.1| 302|Homo sapiens hypothetical protein pr... 100 4e-20
BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS... 100 4e-20
AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein pr... 100 4e-20
AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteini... 100 4e-20
BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein pr... 99 7e-20
BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 1... 99 7e-20
BC016881-1|AAH16881.1| 638|Homo sapiens Unknown (protein for IM... 99 7e-20
AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 1... 99 7e-20
AK055435-1|BAB70922.1| 634|Homo sapiens protein ( Homo sapiens ... 99 7e-20
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 98 9e-20
AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protei... 98 9e-20
AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein. 97 2e-19
BC012056-1|AAH12056.1| 173|Homo sapiens ASB13 protein protein. 97 2e-19
AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6... 97 2e-19
AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6... 97 2e-19
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 97 3e-19
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 97 3e-19
BC013172-1|AAH13172.1| 294|Homo sapiens ankyrin repeat and SOCS... 97 3e-19
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 97 3e-19
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 97 3e-19
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 97 3e-19
AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein pr... 97 3e-19
AK000643-1|BAA91302.1| 262|Homo sapiens protein ( Homo sapiens ... 97 3e-19
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 97 3e-19
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 96 4e-19
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 96 4e-19
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 96 4e-19
AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containi... 96 4e-19
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 96 4e-19
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 96 4e-19
BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protei... 96 5e-19
BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 2... 96 5e-19
BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III an... 96 5e-19
AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protei... 96 5e-19
BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein. 95 8e-19
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 95 1e-18
BX537857-1|CAD97864.1| 306|Homo sapiens hypothetical protein pr... 94 2e-18
AB075861-1|BAB85567.1| 863|Homo sapiens KIAA1981 protein protein. 93 2e-18
AL080091-1|CAB45706.2| 266|Homo sapiens hypothetical protein pr... 93 3e-18
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 93 3e-18
CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein. 92 6e-18
BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS... 92 6e-18
AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS... 92 6e-18
AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein. 92 6e-18
AB033081-1|BAA86569.2| 1232|Homo sapiens KIAA1255 protein protein. 92 6e-18
BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein. 92 8e-18
BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS... 92 8e-18
BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS... 92 8e-18
AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS... 92 8e-18
AK125360-1|BAC86146.1| 588|Homo sapiens protein ( Homo sapiens ... 92 8e-18
AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens ... 92 8e-18
AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein. 92 8e-18
AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein. 92 8e-18
AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS... 92 8e-18
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 90 2e-17
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 90 2e-17
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 90 2e-17
AF308292-1|AAG48260.1| 352|Homo sapiens serologically defined b... 90 3e-17
AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens ... 87 2e-16
AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein. 87 2e-16
L10381-1|AAA18032.1| 741|Homo sapiens 2-5A-dependent RNase prot... 87 2e-16
BC115697-1|AAI15698.1| 741|Homo sapiens ribonuclease L (2',5'-o... 87 2e-16
BC114433-1|AAI14434.1| 741|Homo sapiens ribonuclease L protein. 87 2e-16
BC113481-1|AAI13482.1| 349|Homo sapiens ankyrin repeat and SOCS... 87 2e-16
BC113479-1|AAI13480.1| 349|Homo sapiens ankyrin repeat and SOCS... 87 2e-16
BC090934-1|AAH90934.1| 652|Homo sapiens RNASEL protein protein. 87 2e-16
BC025024-1|AAH25024.1| 318|Homo sapiens Unknown (protein for IM... 87 2e-16
AY337578-1|AAQ17469.1| 233|Homo sapiens ankyrin repeat and SOCS... 87 2e-16
AL138776-1|CAH71322.1| 741|Homo sapiens ribonuclease L (2',5'-o... 87 2e-16
AF156779-1|AAD41896.1| 426|Homo sapiens ASB-4 protein protein. 87 2e-16
AC003079-1|AAB83943.2| 426|Homo sapiens unknown protein. 87 2e-16
AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein pr... 87 3e-16
AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein. 87 3e-16
BC032799-1|AAH32799.1| 201|Homo sapiens ANKRD7 protein protein. 86 4e-16
AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein. 86 4e-16
U05681-1|AAC51348.1| 368|Homo sapiens B-cell leukemia/lymphoma ... 86 5e-16
M31732-1|AAA51815.1| 446|Homo sapiens BCL3 protein. 86 5e-16
BC064993-1|AAH64993.1| 446|Homo sapiens B-cell CLL/lymphoma 3 p... 86 5e-16
X61498-1|CAA43715.1| 933|Homo sapiens NF-kB subunit protein. 85 9e-16
S76638-1|AAB21124.1| 900|Homo sapiens p50-NF-kappa B homolog pr... 85 9e-16
BT009769-1|AAP88771.1| 899|Homo sapiens nuclear factor of kappa... 85 9e-16
BC002844-1|AAH02844.1| 899|Homo sapiens nuclear factor of kappa... 85 9e-16
AY865619-1|AAW56071.1| 900|Homo sapiens nuclear factor of kappa... 85 9e-16
AL121928-1|CAC08399.1| 900|Homo sapiens nuclear factor of kappa... 85 9e-16
AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat... 85 9e-16
AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein. 85 1e-15
D87930-1|BAA22378.1| 1030|Homo sapiens myosin phosphatase target... 84 2e-15
BC118585-1|AAI18586.1| 273|Homo sapiens ASB16 protein protein. 84 2e-15
BC118584-1|AAI18585.1| 273|Homo sapiens ASB16 protein protein. 84 2e-15
BC111752-1|AAI11753.1| 1030|Homo sapiens PPP1R12A protein protein. 84 2e-15
BC092481-1|AAH92481.1| 730|Homo sapiens PPP1R12A protein protein. 84 2e-15
BC047898-1|AAH47898.1| 692|Homo sapiens PPP1R12A protein protein. 84 2e-15
AY380574-1|AAQ88438.1| 974|Homo sapiens myosin phosphatase targ... 84 2e-15
AF458589-1|AAM49717.1| 995|Homo sapiens myosin phosphatase targ... 84 2e-15
AB037360-1|BAA90300.1| 1166|Homo sapiens ANKHZN protein. 84 2e-15
CR456543-1|CAG30429.1| 806|Homo sapiens PLA2G6 protein. 84 2e-15
BC036742-1|AAH36742.2| 806|Homo sapiens phospholipase A2, group... 84 2e-15
AY522921-1|AAR92478.1| 806|Homo sapiens phospholipase A2, group... 84 2e-15
AL022322-2|CAA18446.1| 806|Homo sapiens phospholipase A2, group... 84 2e-15
AF117692-1|AAD30424.1| 806|Homo sapiens calcium-independent pho... 84 2e-15
AF116267-1|AAF34728.1| 806|Homo sapiens calcium-independent pho... 84 2e-15
AF102989-1|AAD41723.1| 806|Homo sapiens Ca2+-independent phosph... 84 2e-15
AF064594-1|AAC97486.1| 806|Homo sapiens calcium-independent pho... 84 2e-15
BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome, ma... 83 3e-15
AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome, ma... 83 3e-15
M58603-1|AAA36360.1| 968|Homo sapiens nuclear factor kappa-B DN... 83 5e-15
M55643-1|AAA36361.1| 969|Homo sapiens factor KBF1 protein. 83 5e-15
D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein. 83 5e-15
BC051765-1|AAH51765.1| 969|Homo sapiens nuclear factor of kappa... 83 5e-15
BC033210-1|AAH33210.1| 550|Homo sapiens NFKB1 protein protein. 83 5e-15
BC014558-1|AAH14558.1| 627|Homo sapiens fem-1 homolog b (C. ele... 83 5e-15
BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome, ma... 83 5e-15
BC010122-1|AAH10122.1| 627|Homo sapiens fem-1 homolog b (C. ele... 83 5e-15
AY557346-1|AAS67920.1| 273|Homo sapiens ankyrin repeat and SOCS... 83 5e-15
AY223820-1|AAO30127.1| 968|Homo sapiens nuclear factor of kappa... 83 5e-15
AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome, ma... 83 5e-15
AF213884-1|AAF35232.1| 968|Homo sapiens nuclear factor of kappa... 83 5e-15
AF204883-1|AAF69303.1| 627|Homo sapiens FEM1 beta protein. 83 5e-15
AF178632-1|AAF05314.1| 627|Homo sapiens FEM-1-like death recept... 83 5e-15
AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit ... 83 5e-15
AB007856-1|BAA23692.2| 627|Homo sapiens KIAA0396 protein. 83 5e-15
X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein. 82 6e-15
BC051904-1|AAH51904.1| 752|Homo sapiens phospholipase A2, group... 82 6e-15
BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1... 82 6e-15
AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat do... 82 6e-15
AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1... 82 6e-15
AF102988-1|AAD41722.1| 752|Homo sapiens Ca2+-independent phosph... 82 6e-15
AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens ... 81 1e-14
DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein. 81 1e-14
DQ388145-2|ABD72216.1| 1482|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388144-2|ABD72214.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388143-2|ABD72212.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388142-2|ABD72210.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388141-2|ABD72208.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388140-2|ABD72206.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388139-2|ABD72204.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388138-2|ABD72202.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388137-2|ABD72200.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388136-2|ABD72198.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388135-2|ABD72196.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388134-2|ABD72194.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388133-2|ABD72192.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388132-2|ABD72190.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388131-2|ABD72188.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388130-2|ABD72186.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388129-2|ABD72184.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ388128-2|ABD72182.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ356264-2|ABC87066.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ356263-2|ABC87064.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ356262-2|ABC87062.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ356261-2|ABC87060.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ356260-2|ABC87058.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ356259-2|ABC87056.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ356258-2|ABC87054.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ356257-2|ABC87052.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ354391-2|ABC79055.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ354390-2|ABC79053.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ354389-2|ABC79051.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
DQ354388-2|ABC79049.1| 1663|Homo sapiens CTTNBP2 protein. 81 1e-14
BC106000-1|AAI06001.1| 1663|Homo sapiens cortactin binding prote... 81 1e-14
AF377960-1|AAL32176.1| 1663|Homo sapiens cortactin-binding prote... 81 1e-14
AB051545-1|BAB21849.1| 1662|Homo sapiens KIAA1758 protein protein. 81 1e-14
AB032965-1|BAA86453.1| 1124|Homo sapiens KIAA1139 protein protein. 81 1e-14
U13048-1|AAA65710.1| 348|Homo sapiens nuclear respiratory facto... 81 2e-14
U13046-1|AAA65708.1| 383|Homo sapiens nuclear respiratory facto... 81 2e-14
D13317-1|BAA02574.1| 383|Homo sapiens transcription factor E4TF... 81 2e-14
D13316-1|BAA02573.1| 347|Homo sapiens transcription factor E4TF... 81 2e-14
BC036080-1|AAH36080.1| 383|Homo sapiens GA binding protein tran... 81 2e-14
EF041819-1|ABL09300.1| 782|Homo sapiens several ankyrin repeat ... 80 2e-14
BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5... 80 3e-14
AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5... 80 3e-14
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 79 4e-14
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 79 4e-14
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 79 4e-14
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 79 4e-14
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 79 4e-14
Z47748-1|CAB94757.1| 969|Homo sapiens NFKB1 protein. 79 6e-14
DQ152234-1|AAZ77790.1| 707|Homo sapiens Shank2E protein. 79 6e-14
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 79 6e-14
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 79 6e-14
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 79 6e-14
AK027869-1|BAB55419.1| 773|Homo sapiens protein ( Homo sapiens ... 79 6e-14
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 79 6e-14
BC063609-1|AAH63609.1| 423|Homo sapiens NFKBIE protein protein. 79 8e-14
BC045621-1|AAH45621.1| 198|Homo sapiens ANKRD42 protein protein. 79 8e-14
BC011676-1|AAH11676.2| 423|Homo sapiens NFKBIE protein protein. 79 8e-14
AL357148-2|CAI16567.1| 1341|Homo sapiens breast cancer antigen N... 79 8e-14
AL357148-1|CAI16568.1| 1460|Homo sapiens ankyrin repeat domain 3... 79 8e-14
AL157387-4|CAH71319.1| 1460|Homo sapiens ankyrin repeat domain 3... 79 8e-14
AL157387-3|CAH71320.1| 1341|Homo sapiens breast cancer antigen N... 79 8e-14
AL139392-10|CAI20103.1| 500|Homo sapiens nuclear factor of kapp... 79 8e-14
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 79 8e-14
AF261937-1|AAM27002.1| 361|Homo sapiens NFKBIE protein protein. 79 8e-14
AK124559-1|BAC85884.1| 1005|Homo sapiens protein ( Homo sapiens ... 78 1e-13
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 78 1e-13
AF269087-1|AAK27325.1| 1341|Homo sapiens breast cancer antigen N... 78 1e-13
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 78 1e-13
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 78 1e-13
BC127623-1|AAI27624.1| 458|Homo sapiens ACTBL1 protein protein. 77 2e-13
BC127123-1|AAI27124.1| 581|Homo sapiens protein expressed in pr... 77 2e-13
BC101006-1|AAI01007.1| 581|Homo sapiens protein expressed in pr... 77 2e-13
BC101005-1|AAI01006.1| 544|Homo sapiens POTE15 protein protein. 77 2e-13
BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 2... 77 2e-13
BC050324-1|AAH50324.1| 632|Homo sapiens zinc finger, DHHC-type ... 77 2e-13
AY465173-1|AAS58872.1| 581|Homo sapiens POTE15A protein. 77 2e-13
AY465172-1|AAS58871.1| 486|Homo sapiens POTE14C protein. 77 2e-13
AY465170-1|AAS58869.1| 544|Homo sapiens POTE15B protein. 77 2e-13
AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein pr... 77 2e-13
AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein. 77 2e-13
AB097035-1|BAC77388.1| 622|Homo sapiens putative MAPK activatin... 77 2e-13
AB097013-1|BAC77366.1| 622|Homo sapiens putative NFkB activatin... 77 2e-13
AB023163-1|BAA76790.1| 667|Homo sapiens KIAA0946 protein protein. 77 2e-13
DQ508934-1|ABF57994.1| 591|Homo sapiens SARP3 protein. 77 2e-13
CR545463-1|CAM28350.1| 545|Homo sapiens protein expressed in pr... 77 2e-13
BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2... 77 2e-13
BC007020-1|AAH07020.2| 156|Homo sapiens ANKRD7 protein protein. 77 2e-13
AY462874-1|AAS58868.1| 508|Homo sapiens POTE14A protein. 77 2e-13
AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2... 77 2e-13
AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2... 77 2e-13
AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein ... 77 2e-13
AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin... 77 2e-13
AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin... 77 2e-13
AF163302-1|AAD45121.1| 2161|Homo sapiens somatostatin receptor i... 77 2e-13
AC007874-1|AAF19231.1| 131|Homo sapiens WUGSC:H_DJ1035O02.1 pro... 77 2e-13
AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein ... 77 2e-13
EF523384-1|ABP57734.1| 1075|Homo sapiens POTE-2 alpha-actin prot... 77 3e-13
AY462871-1|AAS58865.1| 712|Homo sapiens POTE2A protein. 77 3e-13
AL442128-2|CAH73039.1| 420|Homo sapiens ankyrin repeat domain 1... 77 3e-13
AL157875-2|CAH70238.1| 420|Homo sapiens ankyrin repeat domain 1... 77 3e-13
AK095193-1|BAC04496.1| 389|Homo sapiens protein ( Homo sapiens ... 77 3e-13
U13047-1|AAA65709.1| 360|Homo sapiens nuclear respiratory facto... 76 4e-13
U13045-1|AAA65707.1| 395|Homo sapiens nuclear respiratory facto... 76 4e-13
DQ309791-1|ABC48694.1| 871|Homo sapiens SamCystin protein. 76 4e-13
BT006652-1|AAP35298.1| 360|Homo sapiens GA binding protein tran... 76 4e-13
BC050702-1|AAH50702.1| 395|Homo sapiens GA binding protein tran... 76 4e-13
BC028407-1|AAH28407.1| 619|Homo sapiens ankyrin repeat domain 3... 76 4e-13
BC016910-1|AAH16910.1| 360|Homo sapiens GA binding protein tran... 76 4e-13
AY462868-1|AAS58862.1| 376|Homo sapiens POTE2D protein. 76 4e-13
AL807776-3|CAM13062.1| 871|Homo sapiens ankyrin repeat and ster... 76 4e-13
AL353782-4|CAM14169.1| 871|Homo sapiens ankyrin repeat and ster... 76 4e-13
AK000100-1|BAA90945.1| 420|Homo sapiens protein ( Homo sapiens ... 76 4e-13
BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 2... 76 5e-13
AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat p... 76 5e-13
AK057862-1|BAB71599.1| 306|Homo sapiens protein ( Homo sapiens ... 76 5e-13
AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containi... 76 5e-13
AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyri... 76 5e-13
AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein. 76 5e-13
L40407-1|AAC41742.1| 338|Homo sapiens thyroid receptor interact... 75 7e-13
BT006743-1|AAP35389.1| 356|Homo sapiens nuclear factor of kappa... 75 7e-13
BC015528-1|AAH15528.1| 356|Homo sapiens nuclear factor of kappa... 75 7e-13
AY736284-1|AAU10088.1| 356|Homo sapiens nuclear factor of kappa... 75 7e-13
AY172978-1|AAO23914.1| 584|Homo sapiens POTE protein. 75 7e-13
AB209784-1|BAD93021.1| 361|Homo sapiens NF-kappaB inhibitor bet... 75 7e-13
AY462869-1|AAS58863.1| 498|Homo sapiens POTE8A protein. 75 9e-13
AB024494-1|BAC22089.1| 633|Homo sapiens huntingtin interacting ... 75 9e-13
BC066981-1|AAH66981.1| 381|Homo sapiens POTE15 protein protein. 75 1e-12
BC104946-1|AAI04947.1| 309|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
BC093883-1|AAH93883.1| 309|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
BC069555-1|AAH69555.1| 309|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
BC069436-1|AAH69436.1| 309|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
AL356317-1|CAI39932.1| 309|Homo sapiens ankyrin repeat and SOCS... 74 2e-12
AF403030-1|AAL57349.1| 308|Homo sapiens ankyrin repeat domain-c... 74 2e-12
AY462873-1|AAS58867.1| 376|Homo sapiens POTE2C protein. 74 2e-12
AY057056-1|AAL25260.1| 151|Homo sapiens hepatocellular carcinom... 74 2e-12
AL031177-6|CAI43131.1| 151|Homo sapiens proteasome (prosome, ma... 74 2e-12
AK021564-1|BAB13844.1| 140|Homo sapiens protein ( Homo sapiens ... 74 2e-12
AF312028-1|AAG60045.1| 782|Homo sapiens myosin binding subunit ... 74 2e-12
AB209452-1|BAD92689.1| 736|Homo sapiens protein phosphatase 1, ... 74 2e-12
AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens ... 73 3e-12
AY462870-1|AAS58864.1| 452|Homo sapiens POTE8B protein. 73 4e-12
BC071771-1|AAH71771.1| 239|Homo sapiens KIAA1641 protein protein. 73 5e-12
BC028369-1|AAH28369.1| 617|Homo sapiens fem-1 homolog c (C. ele... 73 5e-12
AY249188-1|AAO64429.1| 617|Homo sapiens FEM1C protein. 73 5e-12
AL365415-1|CAB96957.1| 271|Homo sapiens similar to (NP_034322.1... 73 5e-12
AF391093-1|AAL37627.1| 617|Homo sapiens FEM1A protein. 73 5e-12
AB058688-1|BAB47414.1| 617|Homo sapiens KIAA1785 protein protein. 73 5e-12
BC030990-1|AAH30990.1| 276|Homo sapiens ZDHHC17 protein protein. 72 7e-12
AL390918-2|CAI15822.1| 940|Homo sapiens protein ( Human DNA seq... 72 7e-12
AL390918-1|CAI15821.1| 1858|Homo sapiens protein ( Human DNA seq... 72 7e-12
AL353143-2|CAH73222.1| 940|Homo sapiens protein ( Human DNA seq... 72 7e-12
AL353143-1|CAH73221.1| 1858|Homo sapiens protein ( Human DNA seq... 72 7e-12
AL161431-1|CAI15548.1| 1858|Homo sapiens protein ( Human DNA seq... 72 7e-12
AL157771-2|CAI16367.1| 940|Homo sapiens protein ( Human DNA seq... 72 7e-12
AL157771-1|CAI16366.1| 1858|Homo sapiens protein ( Human DNA seq... 72 7e-12
AL136132-2|CAH70520.1| 940|Homo sapiens protein ( Human DNA seq... 72 7e-12
AL136132-1|CAH70519.1| 1858|Homo sapiens protein ( Human DNA seq... 72 7e-12
AK127806-1|BAC87143.1| 935|Homo sapiens protein ( Homo sapiens ... 72 7e-12
AK074570-1|BAC11066.1| 239|Homo sapiens protein ( Homo sapiens ... 72 7e-12
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 169 bits (411), Expect = 3e-41
Identities = 113/306 (36%), Positives = 155/306 (50%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + LL +P+ G T LH++C + ++LLL HGA +
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGA---S 425
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
+ TE+ TP+H AA + V L+ HGA N + + LH A S EVV+ L
Sbjct: 426 IQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
++ GA + +TPLH++A LG A + LL GA AA G T LHL+A +GH
Sbjct: 486 VQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGY-TPLHLSAREGH 544
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LLDHGA + +G TPLH+A LEV +L+ + A A G TPLH
Sbjct: 545 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 604
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A + +A LLL GA P+AA GYTPLHIAA LL+YG D T
Sbjct: 605 AAHYDNQ--KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTR 662
Query: 385 GGVSAL 390
G++++
Sbjct: 663 QGIASV 668
Score = 160 bits (389), Expect = 1e-38
Identities = 113/305 (37%), Positives = 149/305 (48%), Gaps = 8/305 (2%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LGK+ ++ +LL+ G P+ +G T LHLS G E+ LLDHGA + +T+
Sbjct: 509 LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA---SLSITTKKG 565
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
TPLH AA L +L+ A +A G S +PLH A D +V LL+ GA P
Sbjct: 566 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 625
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
TPLH+AA LL GAD A G A+ +HLAA++GH + LLL
Sbjct: 626 AAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIAS-VHLAAQEGHVDMVSLLL 684
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
A+++ N G TPLHLA + V E+LV++ A V A+ G TPLH G
Sbjct: 685 GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN-- 742
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
I LL A NA GYTPLH AA + + +LL T G +AL
Sbjct: 743 IKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG- 801
Query: 393 IVRRV 397
I RR+
Sbjct: 802 IARRL 806
Score = 150 bits (364), Expect = 2e-35
Identities = 99/295 (33%), Positives = 142/295 (48%), Gaps = 7/295 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ V D++ + T LH++ G + K+LLD A+PN + TPLH A
Sbjct: 353 LLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPN---AKALNGFTPLHIACK 409
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ HGA + A S +P+H A +V +L+ GA P+T V ET
Sbjct: 410 KNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETA 469
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G A + L+ GA V A + T LH++A G A+ + LL GA +
Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ-TPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLHL+ +V L+D A + G TPLH A G ++A LLL
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK--LEVANLLLQ 586
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
A P+AA G TPLH+AA + LLLLD G G + L ++
Sbjct: 587 KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 641
Score = 150 bits (364), Expect = 2e-35
Identities = 103/301 (34%), Positives = 145/301 (48%), Gaps = 7/301 (2%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC + ++ LLK G + ++G T +H++ +G V L+ HGA PNT +
Sbjct: 407 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 466
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
ET LH AA + V+ L+ GA V A D++PLH + ++V++LL+ GA
Sbjct: 467 ETA---LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 523
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
P+ TPLH++A G LL+ GA + G T LH+AA+ G E A
Sbjct: 524 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKG-FTPLHVAAKYGKLEVAN 582
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL A D G TPLH+A + +V +L+D+ A A +G TPLH I
Sbjct: 583 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLH--IAAK 640
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
DIA LL GAD NA G +H+AA V LLL +V L G++
Sbjct: 641 KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTP 700
Query: 390 L 390
L
Sbjct: 701 L 701
Score = 133 bits (322), Expect = 2e-30
Identities = 97/306 (31%), Positives = 146/306 (47%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L++ G + +T LH+S +G + V+ LL GA PN
Sbjct: 468 TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPN- 526
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKEL 204
++T + TPLH +A L+ HGA ++ +PLH A EV L
Sbjct: 527 --AATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ A PD TPLHVAA + LLL+ GA AA G T LH+AA+
Sbjct: 585 LQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY-TPLHIAAKKNQ 643
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LL++GA + +G +HLA +++V +L+ R A+V + G TPLH
Sbjct: 644 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHL 703
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A ++A +L++ GA +A GYTPLH+ V LL + V +T
Sbjct: 704 AAQEDR--VNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTK 761
Query: 385 GGVSAL 390
G + L
Sbjct: 762 NGYTPL 767
Score = 128 bits (308), Expect = 9e-29
Identities = 98/292 (33%), Positives = 142/292 (48%), Gaps = 15/292 (5%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+LL+ + D G T LH++ L G E VK+L+ +GA+ N + ++ TPL+ AA
Sbjct: 92 ELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVN---AQSQNGFTPLYMAA 148
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
L VK L+ +GA + D +PL A+ +VV LLE DT
Sbjct: 149 QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE----NDTKGKVRLP 204
Query: 221 PLHVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
LH+AA LLL + ADV + G T LH+AA G+ A LLL+ A +
Sbjct: 205 ALHIAARKDDTKAAALLLQNDNNADVESKSG---FTPLHIAAHYGNINVATLLLNRAAAV 261
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
D+ TPLH+A+ + +V++L+DR A + AK DG TPLH G + +
Sbjct: 262 DFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHE--QVVEM 319
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL A + G +PLH+A + CV LLL + V TN ++AL
Sbjct: 320 LLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTAL 371
Score = 126 bits (305), Expect = 2e-28
Identities = 99/288 (34%), Positives = 138/288 (47%), Gaps = 11/288 (3%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
+K GVD + + G LHL+ G E V LL A+ D++T+ T LH A+ A
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANV---DAATKKGNTALHIASLA 117
Query: 164 KSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
VKVL+ +GA+VNA + +PL+ A + EVVK LL+ GA TPL
Sbjct: 118 GQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPL 177
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
VA G LLL G + ALH+AA + A LLL + + D +
Sbjct: 178 AVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVES 232
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G TPLH+A ++ V +L++R A V + TPLH A RG ++ +LLL
Sbjct: 233 KSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG--NANMVKLLLDR 290
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA +A G TPLH A + V +LLD + +T G+S L
Sbjct: 291 GAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPL 338
Score = 114 bits (275), Expect = 9e-25
Identities = 92/288 (31%), Positives = 127/288 (44%), Gaps = 7/288 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G+ VKLLLD GA D+ T TPLHC A + V++L+ A
Sbjct: 270 TPLHVASKRGNANMVKLLLDRGAKI---DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP 326
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ + + SPLH A D V+ LL+ D T LHVAA G K+L
Sbjct: 327 ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 386
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L+ A+ A G T LH+A + + LLL HGA I G TP+H+A
Sbjct: 387 LDKKANPNAKALNG-FTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 445
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +V L+ A + G T LH A R +A ++ R L+ GA A TPL
Sbjct: 446 VNIVSQLMHHGASPNTTNVRGETALHMA-ARSGQA-EVVRYLVQDGAQVEAKAKDDQTPL 503
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
HI+A + V LL G T G + L R + + +L
Sbjct: 504 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 551
Score = 113 bits (271), Expect = 3e-24
Identities = 86/286 (30%), Positives = 128/286 (44%), Gaps = 7/286 (2%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
LH++ + LLL + N D +++ TPLH AA ++ +L+ A V+
Sbjct: 206 LHIAARKDDTKAAALLLQND---NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 262
Query: 181 -AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
+D +PLH A +VK LL+ GA D TPLH A G ++LL+
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A + + G + LH+A + H C +LLL H +D T LH+A +
Sbjct: 323 RAAPILSKTKNG-LSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYK 381
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
V ++L+D+ A+ AK +G TPLH A + + LLL GA A G TP+H+
Sbjct: 382 VAKVLLDKKANPNAKALNGFTPLHIACKKNR--IKVMELLLKHGASIQAVTESGLTPIHV 439
Query: 360 AALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA V L+ +G G +AL R + RYL
Sbjct: 440 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485
Score = 109 bits (262), Expect = 4e-23
Identities = 94/311 (30%), Positives = 137/311 (44%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L+ G + + G T L+++ E VK LLD+GA +
Sbjct: 109 TALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSL 168
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V +L+ + L LH A D + LL
Sbjct: 169 ---ATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLP---ALHIAARKDDTKAAALLL 222
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ D TPLH+AA G+ + LLLN A V T LH+A++ G+A
Sbjct: 223 QNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT-ARNDITPLHVASKRGNA 281
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+LLLD GA ID G TPLH + +VVEML+DR A + +K +G +PLH A
Sbjct: 282 NMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMA 341
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
C +LLL + N T LH+AA +LLD + +
Sbjct: 342 TQGDHLNC--VQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALN 399
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 400 GFTPLHIACKK 410
Score = 84.2 bits (199), Expect = 2e-15
Identities = 68/229 (29%), Positives = 96/229 (41%), Gaps = 6/229 (2%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+A G GL + A + + + L LL G P G T LH++ + L
Sbjct: 592 DAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 650
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLS 195
L++GA N + T +H AA + V +L+ A+VN + S +PLH A
Sbjct: 651 LEYGADAN---AVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQE 707
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
D V + L+ GA D TPLHV G+ LL A V A G T
Sbjct: 708 DRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGY-TP 766
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LH AA+ GH +LL + A + G T L +A + VV+ L
Sbjct: 767 LHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 815
Score = 83.0 bits (196), Expect = 3e-15
Identities = 76/240 (31%), Positives = 106/240 (44%), Gaps = 12/240 (5%)
Query: 160 AASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA A L I +G D+N + + LH A EVV ELL+ A D
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
T LH+A+ G A K+L+ GA+V A G T L++AA++ H E + LLD+GA
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNG-FTPLYMAAQENHLEVVKFLLDNGASQ 166
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACD--IA 336
G TPL +A +VV +L++ D G+ L A+ AR D A
Sbjct: 167 SLATEDGFTPLAVALQQGHDQVVSLLLE-------NDTKGKVRL-PALHIAARKDDTKAA 218
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
LLL + + G+TPLHIAA LLL+ V ++ L +R
Sbjct: 219 ALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKR 278
Score = 77.0 bits (181), Expect = 2e-13
Identities = 54/158 (34%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Query: 253 ATALHL-AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
A A +L AA GH E A + +G I+ N G LHLA+ +EVV L+ R A+V
Sbjct: 41 ANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANV 100
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
A G T LH A + G ++ ++L++ GA+ NA G+TPL++AA V
Sbjct: 101 DAATKKGNTALHIASLAGQ--AEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKF 158
Query: 372 LLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
LLD G +L T G + L+ +++ D + L + D
Sbjct: 159 LLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEND 196
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 169 bits (411), Expect = 3e-41
Identities = 113/306 (36%), Positives = 155/306 (50%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + LL +P+ G T LH++C + ++LLL HGA +
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGA---S 425
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
+ TE+ TP+H AA + V L+ HGA N + + LH A S EVV+ L
Sbjct: 426 IQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
++ GA + +TPLH++A LG A + LL GA AA G T LHL+A +GH
Sbjct: 486 VQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGY-TPLHLSAREGH 544
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LLDHGA + +G TPLH+A LEV +L+ + A A G TPLH
Sbjct: 545 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 604
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A + +A LLL GA P+AA GYTPLHIAA LL+YG D T
Sbjct: 605 AAHYDNQ--KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTR 662
Query: 385 GGVSAL 390
G++++
Sbjct: 663 QGIASV 668
Score = 153 bits (370), Expect = 3e-36
Identities = 112/305 (36%), Positives = 147/305 (48%), Gaps = 13/305 (4%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LGK+ ++ +LL+ G P+ +G T LHLS G E+ LLDHGA + +T+
Sbjct: 509 LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA---SLSITTKKG 565
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
TPLH AA L +L+ A +A G S +PLH A D +V LL+ GA P
Sbjct: 566 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 625
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
TPLH+AA LL GAD A G A+ +HLAA++GH + LLL
Sbjct: 626 AAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIAS-VHLAAQEGHVDMVSLLL 684
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
A++ G TPLHLA + V E+LV++ A V A+ G TPLH G
Sbjct: 685 GRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN-- 737
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
I LL A NA GYTPLH AA + + +LL T G +AL
Sbjct: 738 IKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG- 796
Query: 393 IVRRV 397
I RR+
Sbjct: 797 IARRL 801
Score = 150 bits (364), Expect = 2e-35
Identities = 99/295 (33%), Positives = 142/295 (48%), Gaps = 7/295 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ V D++ + T LH++ G + K+LLD A+PN + TPLH A
Sbjct: 353 LLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPN---AKALNGFTPLHIACK 409
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ HGA + A S +P+H A +V +L+ GA P+T V ET
Sbjct: 410 KNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETA 469
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G A + L+ GA V A + T LH++A G A+ + LL GA +
Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ-TPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLHL+ +V L+D A + G TPLH A G ++A LLL
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK--LEVANLLLQ 586
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
A P+AA G TPLH+AA + LLLLD G G + L ++
Sbjct: 587 KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 641
Score = 128 bits (308), Expect = 9e-29
Identities = 98/292 (33%), Positives = 142/292 (48%), Gaps = 15/292 (5%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+LL+ + D G T LH++ L G E VK+L+ +GA+ N + ++ TPL+ AA
Sbjct: 92 ELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVN---AQSQNGFTPLYMAA 148
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
L VK L+ +GA + D +PL A+ +VV LLE DT
Sbjct: 149 QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE----NDTKGKVRLP 204
Query: 221 PLHVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
LH+AA LLL + ADV + G T LH+AA G+ A LLL+ A +
Sbjct: 205 ALHIAARKDDTKAAALLLQNDNNADVESKSG---FTPLHIAAHYGNINVATLLLNRAAAV 261
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
D+ TPLH+A+ + +V++L+DR A + AK DG TPLH G + +
Sbjct: 262 DFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHE--QVVEM 319
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL A + G +PLH+A + CV LLL + V TN ++AL
Sbjct: 320 LLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTAL 371
Score = 126 bits (305), Expect = 2e-28
Identities = 99/288 (34%), Positives = 138/288 (47%), Gaps = 11/288 (3%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
+K GVD + + G LHL+ G E V LL A+ D++T+ T LH A+ A
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANV---DAATKKGNTALHIASLA 117
Query: 164 KSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
VKVL+ +GA+VNA + +PL+ A + EVVK LL+ GA TPL
Sbjct: 118 GQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPL 177
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
VA G LLL G + ALH+AA + A LLL + + D +
Sbjct: 178 AVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVES 232
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G TPLH+A ++ V +L++R A V + TPLH A RG ++ +LLL
Sbjct: 233 KSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG--NANMVKLLLDR 290
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA +A G TPLH A + V +LLD + +T G+S L
Sbjct: 291 GAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPL 338
Score = 126 bits (304), Expect = 3e-28
Identities = 97/306 (31%), Positives = 145/306 (47%), Gaps = 12/306 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L++ G + +T LH+S +G + V+ LL GA PN
Sbjct: 468 TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPN- 526
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKEL 204
++T + TPLH +A L+ HGA ++ +PLH A EV L
Sbjct: 527 --AATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ A PD TPLHVAA + LLL+ GA AA G T LH+AA+
Sbjct: 585 LQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY-TPLHIAAKKNQ 643
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LL++GA + +G +HLA +++V +L+ R A+V G TPLH
Sbjct: 644 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHL 698
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A ++A +L++ GA +A GYTPLH+ V LL + V +T
Sbjct: 699 AAQEDR--VNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTK 756
Query: 385 GGVSAL 390
G + L
Sbjct: 757 NGYTPL 762
Score = 114 bits (275), Expect = 9e-25
Identities = 92/288 (31%), Positives = 127/288 (44%), Gaps = 7/288 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G+ VKLLLD GA D+ T TPLHC A + V++L+ A
Sbjct: 270 TPLHVASKRGNANMVKLLLDRGAKI---DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP 326
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ + + SPLH A D V+ LL+ D T LHVAA G K+L
Sbjct: 327 ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 386
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L+ A+ A G T LH+A + + LLL HGA I G TP+H+A
Sbjct: 387 LDKKANPNAKALNG-FTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 445
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +V L+ A + G T LH A R +A ++ R L+ GA A TPL
Sbjct: 446 VNIVSQLMHHGASPNTTNVRGETALHMA-ARSGQA-EVVRYLVQDGAQVEAKAKDDQTPL 503
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
HI+A + V LL G T G + L R + + +L
Sbjct: 504 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 551
Score = 113 bits (271), Expect = 3e-24
Identities = 86/286 (30%), Positives = 128/286 (44%), Gaps = 7/286 (2%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
LH++ + LLL + N D +++ TPLH AA ++ +L+ A V+
Sbjct: 206 LHIAARKDDTKAAALLLQND---NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 262
Query: 181 -AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
+D +PLH A +VK LL+ GA D TPLH A G ++LL+
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A + + G + LH+A + H C +LLL H +D T LH+A +
Sbjct: 323 RAAPILSKTKNG-LSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYK 381
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
V ++L+D+ A+ AK +G TPLH A + + LLL GA A G TP+H+
Sbjct: 382 VAKVLLDKKANPNAKALNGFTPLHIACKKNR--IKVMELLLKHGASIQAVTESGLTPIHV 439
Query: 360 AALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA V L+ +G G +AL R + RYL
Sbjct: 440 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485
Score = 109 bits (262), Expect = 4e-23
Identities = 94/311 (30%), Positives = 137/311 (44%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L+ G + + G T L+++ E VK LLD+GA +
Sbjct: 109 TALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSL 168
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V +L+ + L LH A D + LL
Sbjct: 169 ---ATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLP---ALHIAARKDDTKAAALLL 222
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ D TPLH+AA G+ + LLLN A V T LH+A++ G+A
Sbjct: 223 QNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT-ARNDITPLHVASKRGNA 281
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+LLLD GA ID G TPLH + +VVEML+DR A + +K +G +PLH A
Sbjct: 282 NMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMA 341
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
C +LLL + N T LH+AA +LLD + +
Sbjct: 342 TQGDHLNC--VQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALN 399
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 400 GFTPLHIACKK 410
Score = 83.0 bits (196), Expect = 3e-15
Identities = 76/240 (31%), Positives = 106/240 (44%), Gaps = 12/240 (5%)
Query: 160 AASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA A L I +G D+N + + LH A EVV ELL+ A D
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
T LH+A+ G A K+L+ GA+V A G T L++AA++ H E + LLD+GA
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNG-FTPLYMAAQENHLEVVKFLLDNGASQ 166
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACD--IA 336
G TPL +A +VV +L++ D G+ L A+ AR D A
Sbjct: 167 SLATEDGFTPLAVALQQGHDQVVSLLLE-------NDTKGKVRL-PALHIAARKDDTKAA 218
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
LLL + + G+TPLHIAA LLL+ V ++ L +R
Sbjct: 219 ALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKR 278
Score = 80.6 bits (190), Expect = 2e-14
Identities = 67/228 (29%), Positives = 94/228 (41%), Gaps = 9/228 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+A G GL + A + + + L LL G P G T LH++ + L
Sbjct: 592 DAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 650
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSD 196
L++GA N + T +H AA + V +L+ NA +S +PLH A D
Sbjct: 651 LEYGADAN---AVTRQGIASVHLAAQEGHVDMVSLLLGR----NANVSGLTPLHLAAQED 703
Query: 197 APEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
V + L+ GA D TPLHV G+ LL A V A G T L
Sbjct: 704 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGY-TPL 762
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
H AA+ GH +LL + A + G T L +A + VV+ L
Sbjct: 763 HQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 810
Score = 77.0 bits (181), Expect = 2e-13
Identities = 54/158 (34%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Query: 253 ATALHL-AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
A A +L AA GH E A + +G I+ N G LHLA+ +EVV L+ R A+V
Sbjct: 41 ANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANV 100
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
A G T LH A + G ++ ++L++ GA+ NA G+TPL++AA V
Sbjct: 101 DAATKKGNTALHIASLAGQ--AEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKF 158
Query: 372 LLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
LLD G +L T G + L+ +++ D + L + D
Sbjct: 159 LLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEND 196
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 169 bits (411), Expect = 3e-41
Identities = 113/306 (36%), Positives = 155/306 (50%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + LL +P+ G T LH++C + ++LLL HGA +
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGA---S 425
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
+ TE+ TP+H AA + V L+ HGA N + + LH A S EVV+ L
Sbjct: 426 IQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
++ GA + +TPLH++A LG A + LL GA AA G T LHL+A +GH
Sbjct: 486 VQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGY-TPLHLSAREGH 544
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LLDHGA + +G TPLH+A LEV +L+ + A A G TPLH
Sbjct: 545 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 604
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A + +A LLL GA P+AA GYTPLHIAA LL+YG D T
Sbjct: 605 AAHYDNQ--KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTR 662
Query: 385 GGVSAL 390
G++++
Sbjct: 663 QGIASV 668
Score = 153 bits (370), Expect = 3e-36
Identities = 112/305 (36%), Positives = 147/305 (48%), Gaps = 13/305 (4%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LGK+ ++ +LL+ G P+ +G T LHLS G E+ LLDHGA + +T+
Sbjct: 509 LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA---SLSITTKKG 565
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
TPLH AA L +L+ A +A G S +PLH A D +V LL+ GA P
Sbjct: 566 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 625
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
TPLH+AA LL GAD A G A+ +HLAA++GH + LLL
Sbjct: 626 AAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIAS-VHLAAQEGHVDMVSLLL 684
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
A++ G TPLHLA + V E+LV++ A V A+ G TPLH G
Sbjct: 685 GRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN-- 737
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
I LL A NA GYTPLH AA + + +LL T G +AL
Sbjct: 738 IKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG- 796
Query: 393 IVRRV 397
I RR+
Sbjct: 797 IARRL 801
Score = 150 bits (364), Expect = 2e-35
Identities = 99/295 (33%), Positives = 142/295 (48%), Gaps = 7/295 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ V D++ + T LH++ G + K+LLD A+PN + TPLH A
Sbjct: 353 LLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPN---AKALNGFTPLHIACK 409
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ HGA + A S +P+H A +V +L+ GA P+T V ET
Sbjct: 410 KNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETA 469
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G A + L+ GA V A + T LH++A G A+ + LL GA +
Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ-TPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLHL+ +V L+D A + G TPLH A G ++A LLL
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK--LEVANLLLQ 586
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
A P+AA G TPLH+AA + LLLLD G G + L ++
Sbjct: 587 KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 641
Score = 128 bits (308), Expect = 9e-29
Identities = 98/292 (33%), Positives = 142/292 (48%), Gaps = 15/292 (5%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+LL+ + D G T LH++ L G E VK+L+ +GA+ N + ++ TPL+ AA
Sbjct: 92 ELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVN---AQSQNGFTPLYMAA 148
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
L VK L+ +GA + D +PL A+ +VV LLE DT
Sbjct: 149 QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE----NDTKGKVRLP 204
Query: 221 PLHVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
LH+AA LLL + ADV + G T LH+AA G+ A LLL+ A +
Sbjct: 205 ALHIAARKDDTKAAALLLQNDNNADVESKSG---FTPLHIAAHYGNINVATLLLNRAAAV 261
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
D+ TPLH+A+ + +V++L+DR A + AK DG TPLH G + +
Sbjct: 262 DFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHE--QVVEM 319
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL A + G +PLH+A + CV LLL + V TN ++AL
Sbjct: 320 LLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTAL 371
Score = 126 bits (305), Expect = 2e-28
Identities = 99/288 (34%), Positives = 138/288 (47%), Gaps = 11/288 (3%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
+K GVD + + G LHL+ G E V LL A+ D++T+ T LH A+ A
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANV---DAATKKGNTALHIASLA 117
Query: 164 KSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
VKVL+ +GA+VNA + +PL+ A + EVVK LL+ GA TPL
Sbjct: 118 GQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPL 177
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
VA G LLL G + ALH+AA + A LLL + + D +
Sbjct: 178 AVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVES 232
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G TPLH+A ++ V +L++R A V + TPLH A RG ++ +LLL
Sbjct: 233 KSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG--NANMVKLLLDR 290
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA +A G TPLH A + V +LLD + +T G+S L
Sbjct: 291 GAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPL 338
Score = 126 bits (304), Expect = 3e-28
Identities = 97/306 (31%), Positives = 145/306 (47%), Gaps = 12/306 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L++ G + +T LH+S +G + V+ LL GA PN
Sbjct: 468 TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPN- 526
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKEL 204
++T + TPLH +A L+ HGA ++ +PLH A EV L
Sbjct: 527 --AATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ A PD TPLHVAA + LLL+ GA AA G T LH+AA+
Sbjct: 585 LQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY-TPLHIAAKKNQ 643
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LL++GA + +G +HLA +++V +L+ R A+V G TPLH
Sbjct: 644 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHL 698
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A ++A +L++ GA +A GYTPLH+ V LL + V +T
Sbjct: 699 AAQEDR--VNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTK 756
Query: 385 GGVSAL 390
G + L
Sbjct: 757 NGYTPL 762
Score = 114 bits (275), Expect = 9e-25
Identities = 92/288 (31%), Positives = 127/288 (44%), Gaps = 7/288 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G+ VKLLLD GA D+ T TPLHC A + V++L+ A
Sbjct: 270 TPLHVASKRGNANMVKLLLDRGAKI---DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP 326
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ + + SPLH A D V+ LL+ D T LHVAA G K+L
Sbjct: 327 ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 386
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L+ A+ A G T LH+A + + LLL HGA I G TP+H+A
Sbjct: 387 LDKKANPNAKALNG-FTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 445
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +V L+ A + G T LH A R +A ++ R L+ GA A TPL
Sbjct: 446 VNIVSQLMHHGASPNTTNVRGETALHMA-ARSGQA-EVVRYLVQDGAQVEAKAKDDQTPL 503
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
HI+A + V LL G T G + L R + + +L
Sbjct: 504 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 551
Score = 113 bits (271), Expect = 3e-24
Identities = 86/286 (30%), Positives = 128/286 (44%), Gaps = 7/286 (2%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
LH++ + LLL + N D +++ TPLH AA ++ +L+ A V+
Sbjct: 206 LHIAARKDDTKAAALLLQND---NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 262
Query: 181 -AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
+D +PLH A +VK LL+ GA D TPLH A G ++LL+
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A + + G + LH+A + H C +LLL H +D T LH+A +
Sbjct: 323 RAAPILSKTKNG-LSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYK 381
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
V ++L+D+ A+ AK +G TPLH A + + LLL GA A G TP+H+
Sbjct: 382 VAKVLLDKKANPNAKALNGFTPLHIACKKNR--IKVMELLLKHGASIQAVTESGLTPIHV 439
Query: 360 AALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA V L+ +G G +AL R + RYL
Sbjct: 440 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485
Score = 109 bits (262), Expect = 4e-23
Identities = 94/311 (30%), Positives = 137/311 (44%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L+ G + + G T L+++ E VK LLD+GA +
Sbjct: 109 TALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSL 168
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V +L+ + L LH A D + LL
Sbjct: 169 ---ATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLP---ALHIAARKDDTKAAALLL 222
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ D TPLH+AA G+ + LLLN A V T LH+A++ G+A
Sbjct: 223 QNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT-ARNDITPLHVASKRGNA 281
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+LLLD GA ID G TPLH + +VVEML+DR A + +K +G +PLH A
Sbjct: 282 NMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMA 341
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
C +LLL + N T LH+AA +LLD + +
Sbjct: 342 TQGDHLNC--VQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALN 399
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 400 GFTPLHIACKK 410
Score = 83.0 bits (196), Expect = 3e-15
Identities = 76/240 (31%), Positives = 106/240 (44%), Gaps = 12/240 (5%)
Query: 160 AASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA A L I +G D+N + + LH A EVV ELL+ A D
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
T LH+A+ G A K+L+ GA+V A G T L++AA++ H E + LLD+GA
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNG-FTPLYMAAQENHLEVVKFLLDNGASQ 166
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACD--IA 336
G TPL +A +VV +L++ D G+ L A+ AR D A
Sbjct: 167 SLATEDGFTPLAVALQQGHDQVVSLLLE-------NDTKGKVRL-PALHIAARKDDTKAA 218
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
LLL + + G+TPLHIAA LLL+ V ++ L +R
Sbjct: 219 ALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKR 278
Score = 80.6 bits (190), Expect = 2e-14
Identities = 67/228 (29%), Positives = 94/228 (41%), Gaps = 9/228 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+A G GL + A + + + L LL G P G T LH++ + L
Sbjct: 592 DAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 650
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSD 196
L++GA N + T +H AA + V +L+ NA +S +PLH A D
Sbjct: 651 LEYGADAN---AVTRQGIASVHLAAQEGHVDMVSLLLGR----NANVSGLTPLHLAAQED 703
Query: 197 APEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
V + L+ GA D TPLHV G+ LL A V A G T L
Sbjct: 704 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGY-TPL 762
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
H AA+ GH +LL + A + G T L +A + VV+ L
Sbjct: 763 HQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 810
Score = 77.0 bits (181), Expect = 2e-13
Identities = 54/158 (34%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Query: 253 ATALHL-AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
A A +L AA GH E A + +G I+ N G LHLA+ +EVV L+ R A+V
Sbjct: 41 ANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANV 100
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
A G T LH A + G ++ ++L++ GA+ NA G+TPL++AA V
Sbjct: 101 DAATKKGNTALHIASLAGQ--AEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKF 158
Query: 372 LLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
LLD G +L T G + L+ +++ D + L + D
Sbjct: 159 LLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEND 196
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 169 bits (411), Expect = 3e-41
Identities = 113/306 (36%), Positives = 155/306 (50%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + LL +P+ G T LH++C + ++LLL HGA +
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGA---S 425
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
+ TE+ TP+H AA + V L+ HGA N + + LH A S EVV+ L
Sbjct: 426 IQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
++ GA + +TPLH++A LG A + LL GA AA G T LHL+A +GH
Sbjct: 486 VQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGY-TPLHLSAREGH 544
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LLDHGA + +G TPLH+A LEV +L+ + A A G TPLH
Sbjct: 545 EDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHV 604
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A + +A LLL GA P+AA GYTPLHIAA LL+YG D T
Sbjct: 605 AAHYDNQ--KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTR 662
Query: 385 GGVSAL 390
G++++
Sbjct: 663 QGIASV 668
Score = 153 bits (370), Expect = 3e-36
Identities = 112/305 (36%), Positives = 147/305 (48%), Gaps = 13/305 (4%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LGK+ ++ +LL+ G P+ +G T LHLS G E+ LLDHGA + +T+
Sbjct: 509 LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA---SLSITTKKG 565
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
TPLH AA L +L+ A +A G S +PLH A D +V LL+ GA P
Sbjct: 566 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 625
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
TPLH+AA LL GAD A G A+ +HLAA++GH + LLL
Sbjct: 626 AAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIAS-VHLAAQEGHVDMVSLLL 684
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
A++ G TPLHLA + V E+LV++ A V A+ G TPLH G
Sbjct: 685 GRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN-- 737
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
I LL A NA GYTPLH AA + + +LL T G +AL
Sbjct: 738 IKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG- 796
Query: 393 IVRRV 397
I RR+
Sbjct: 797 IARRL 801
Score = 150 bits (364), Expect = 2e-35
Identities = 99/295 (33%), Positives = 142/295 (48%), Gaps = 7/295 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ V D++ + T LH++ G + K+LLD A+PN + TPLH A
Sbjct: 353 LLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPN---AKALNGFTPLHIACK 409
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ HGA + A S +P+H A +V +L+ GA P+T V ET
Sbjct: 410 KNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETA 469
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G A + L+ GA V A + T LH++A G A+ + LL GA +
Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ-TPLHISARLGKADIVQQLLQQGASPNAA 528
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLHL+ +V L+D A + G TPLH A G ++A LLL
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK--LEVANLLLQ 586
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
A P+AA G TPLH+AA + LLLLD G G + L ++
Sbjct: 587 KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 641
Score = 128 bits (308), Expect = 9e-29
Identities = 98/292 (33%), Positives = 142/292 (48%), Gaps = 15/292 (5%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+LL+ + D G T LH++ L G E VK+L+ +GA+ N + ++ TPL+ AA
Sbjct: 92 ELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVN---AQSQNGFTPLYMAA 148
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
L VK L+ +GA + D +PL A+ +VV LLE DT
Sbjct: 149 QENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLE----NDTKGKVRLP 204
Query: 221 PLHVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
LH+AA LLL + ADV + G T LH+AA G+ A LLL+ A +
Sbjct: 205 ALHIAARKDDTKAAALLLQNDNNADVESKSG---FTPLHIAAHYGNINVATLLLNRAAAV 261
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
D+ TPLH+A+ + +V++L+DR A + AK DG TPLH G + +
Sbjct: 262 DFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHE--QVVEM 319
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL A + G +PLH+A + CV LLL + V TN ++AL
Sbjct: 320 LLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTAL 371
Score = 126 bits (305), Expect = 2e-28
Identities = 99/288 (34%), Positives = 138/288 (47%), Gaps = 11/288 (3%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
+K GVD + + G LHL+ G E V LL A+ D++T+ T LH A+ A
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANV---DAATKKGNTALHIASLA 117
Query: 164 KSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
VKVL+ +GA+VNA + +PL+ A + EVVK LL+ GA TPL
Sbjct: 118 GQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPL 177
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
VA G LLL G + ALH+AA + A LLL + + D +
Sbjct: 178 AVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVES 232
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G TPLH+A ++ V +L++R A V + TPLH A RG ++ +LLL
Sbjct: 233 KSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRG--NANMVKLLLDR 290
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA +A G TPLH A + V +LLD + +T G+S L
Sbjct: 291 GAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPL 338
Score = 126 bits (304), Expect = 3e-28
Identities = 97/306 (31%), Positives = 145/306 (47%), Gaps = 12/306 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L++ G + +T LH+S +G + V+ LL GA PN
Sbjct: 468 TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPN- 526
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKEL 204
++T + TPLH +A L+ HGA ++ +PLH A EV L
Sbjct: 527 --AATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ A PD TPLHVAA + LLL+ GA AA G T LH+AA+
Sbjct: 585 LQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGY-TPLHIAAKKNQ 643
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LL++GA + +G +HLA +++V +L+ R A+V G TPLH
Sbjct: 644 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV-----SGLTPLHL 698
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A ++A +L++ GA +A GYTPLH+ V LL + V +T
Sbjct: 699 AAQEDR--VNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTK 756
Query: 385 GGVSAL 390
G + L
Sbjct: 757 NGYTPL 762
Score = 114 bits (275), Expect = 9e-25
Identities = 92/288 (31%), Positives = 127/288 (44%), Gaps = 7/288 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G+ VKLLLD GA D+ T TPLHC A + V++L+ A
Sbjct: 270 TPLHVASKRGNANMVKLLLDRGAKI---DAKTRDGLTPLHCGARSGHEQVVEMLLDRAAP 326
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ + + SPLH A D V+ LL+ D T LHVAA G K+L
Sbjct: 327 ILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVL 386
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L+ A+ A G T LH+A + + LLL HGA I G TP+H+A
Sbjct: 387 LDKKANPNAKALNG-FTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 445
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +V L+ A + G T LH A R +A ++ R L+ GA A TPL
Sbjct: 446 VNIVSQLMHHGASPNTTNVRGETALHMA-ARSGQA-EVVRYLVQDGAQVEAKAKDDQTPL 503
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
HI+A + V LL G T G + L R + + +L
Sbjct: 504 HISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 551
Score = 113 bits (271), Expect = 3e-24
Identities = 86/286 (30%), Positives = 128/286 (44%), Gaps = 7/286 (2%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
LH++ + LLL + N D +++ TPLH AA ++ +L+ A V+
Sbjct: 206 LHIAARKDDTKAAALLLQND---NNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVD 262
Query: 181 -AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
+D +PLH A +VK LL+ GA D TPLH A G ++LL+
Sbjct: 263 FTARNDITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A + + G + LH+A + H C +LLL H +D T LH+A +
Sbjct: 323 RAAPILSKTKNG-LSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYK 381
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
V ++L+D+ A+ AK +G TPLH A + + LLL GA A G TP+H+
Sbjct: 382 VAKVLLDKKANPNAKALNGFTPLHIACKKNR--IKVMELLLKHGASIQAVTESGLTPIHV 439
Query: 360 AALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA V L+ +G G +AL R + RYL
Sbjct: 440 AAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 485
Score = 109 bits (262), Expect = 4e-23
Identities = 94/311 (30%), Positives = 137/311 (44%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L+ G + + G T L+++ E VK LLD+GA +
Sbjct: 109 TALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSL 168
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V +L+ + L LH A D + LL
Sbjct: 169 ---ATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLP---ALHIAARKDDTKAAALLL 222
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ D TPLH+AA G+ + LLLN A V T LH+A++ G+A
Sbjct: 223 QNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFT-ARNDITPLHVASKRGNA 281
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+LLLD GA ID G TPLH + +VVEML+DR A + +K +G +PLH A
Sbjct: 282 NMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMA 341
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
C +LLL + N T LH+AA +LLD + +
Sbjct: 342 TQGDHLNC--VQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALN 399
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 400 GFTPLHIACKK 410
Score = 83.0 bits (196), Expect = 3e-15
Identities = 76/240 (31%), Positives = 106/240 (44%), Gaps = 12/240 (5%)
Query: 160 AASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA A L I +G D+N + + LH A EVV ELL+ A D
Sbjct: 48 AARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKG 107
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
T LH+A+ G A K+L+ GA+V A G T L++AA++ H E + LLD+GA
Sbjct: 108 NTALHIASLAGQAEVVKVLVTNGANVNAQSQNG-FTPLYMAAQENHLEVVKFLLDNGASQ 166
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACD--IA 336
G TPL +A +VV +L++ D G+ L A+ AR D A
Sbjct: 167 SLATEDGFTPLAVALQQGHDQVVSLLLE-------NDTKGKVRL-PALHIAARKDDTKAA 218
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
LLL + + G+TPLHIAA LLL+ V ++ L +R
Sbjct: 219 ALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKR 278
Score = 80.6 bits (190), Expect = 2e-14
Identities = 67/228 (29%), Positives = 94/228 (41%), Gaps = 9/228 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+A G GL + A + + + L LL G P G T LH++ + L
Sbjct: 592 DAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 650
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSD 196
L++GA N + T +H AA + V +L+ NA +S +PLH A D
Sbjct: 651 LEYGADAN---AVTRQGIASVHLAAQEGHVDMVSLLLGR----NANVSGLTPLHLAAQED 703
Query: 197 APEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
V + L+ GA D TPLHV G+ LL A V A G T L
Sbjct: 704 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGY-TPL 762
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
H AA+ GH +LL + A + G T L +A + VV+ L
Sbjct: 763 HQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 810
Score = 77.0 bits (181), Expect = 2e-13
Identities = 54/158 (34%), Positives = 81/158 (51%), Gaps = 3/158 (1%)
Query: 253 ATALHL-AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
A A +L AA GH E A + +G I+ N G LHLA+ +EVV L+ R A+V
Sbjct: 41 ANASYLRAARAGHLEKALDYIKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANV 100
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
A G T LH A + G ++ ++L++ GA+ NA G+TPL++AA V
Sbjct: 101 DAATKKGNTALHIASLAGQ--AEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKF 158
Query: 372 LLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
LLD G +L T G + L+ +++ D + L + D
Sbjct: 159 LLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEND 196
>U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein.
Length = 1088
Score = 169 bits (410), Expect = 4e-41
Identities = 109/289 (37%), Positives = 149/289 (51%), Gaps = 7/289 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL +P+ G T LH++C + ++LLL HGA + + TE+ TP+H AA
Sbjct: 7 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGA---SIQAVTESGLTPIHVAAF 63
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V L+ HGA N + + LH A S EVV+ L++ GA + +TP
Sbjct: 64 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 123
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH++A LG A + LL GA AA G T LHL+A +GH + A LLDHGA +
Sbjct: 124 LHISARLGKADIVQQLLQQGASPNAATTSGY-TPLHLSAREGHEDVAAFLLDHGASLSIT 182
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLH+A LEV +L+ + A A G TPLH A + +A LLL
Sbjct: 183 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQ--KVALLLLD 240
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA P+AA GYTPLHIAA LL+YG D T G++++
Sbjct: 241 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 289
Score = 160 bits (389), Expect = 1e-38
Identities = 113/305 (37%), Positives = 149/305 (48%), Gaps = 8/305 (2%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LGK+ ++ +LL+ G P+ +G T LHLS G E+ LLDHGA + +T+
Sbjct: 130 LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA---SLSITTKKG 186
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
TPLH AA L +L+ A + AG S +PLH A D +V LL+ GA P
Sbjct: 187 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 246
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
TPLH+AA LL GAD A G A ++HLAA++GH + LLL
Sbjct: 247 AAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIA-SVHLAAQEGHVDMVSLLL 305
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
A+++ N G TPLHLA + V E+LV++ A V A+ G TPLH G
Sbjct: 306 GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG--N 363
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
I LL A NA GYTPLH AA + + +LL T G +AL
Sbjct: 364 IKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG- 422
Query: 393 IVRRV 397
I RR+
Sbjct: 423 IARRL 427
Score = 150 bits (364), Expect = 2e-35
Identities = 103/301 (34%), Positives = 145/301 (48%), Gaps = 7/301 (2%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC + ++ LLK G + ++G T +H++ +G V L+ HGA PNT +
Sbjct: 28 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 87
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
E T LH AA + V+ L+ GA V A D++PLH + ++V++LL+ GA
Sbjct: 88 E---TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 144
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
P+ TPLH++A G LL+ GA + G T LH+AA+ G E A
Sbjct: 145 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKG-FTPLHVAAKYGKLEVAN 203
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL A D G TPLH+A + +V +L+D+ A A +G TPLH I
Sbjct: 204 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLH--IAAK 261
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
DIA LL GAD NA G +H+AA V LLL +V L G++
Sbjct: 262 KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTP 321
Query: 390 L 390
L
Sbjct: 322 L 322
Score = 136 bits (330), Expect = 2e-31
Identities = 90/262 (34%), Positives = 125/262 (47%), Gaps = 7/262 (2%)
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAVL 194
LLD A+PN + TPLH A + +++L+ HGA + A S +P+H A
Sbjct: 7 LLDKKANPN---AKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAF 63
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+V +L+ GA P+T V ET LH+AA G A + L+ GA V A + T
Sbjct: 64 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ-T 122
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH++A G A+ + LL GA + G TPLHL+ +V L+D A +
Sbjct: 123 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSIT 182
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G TPLH A G ++A LLL A P+AA G TPLH+AA + LLLLD
Sbjct: 183 TKKGFTPLHVAAKYGK--LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 240
Query: 375 YGGDVTLRTNGGVSALSFIVRR 396
G G + L ++
Sbjct: 241 QGASPHAAAKNGYTPLHIAAKK 262
Score = 132 bits (320), Expect = 3e-30
Identities = 97/306 (31%), Positives = 140/306 (45%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T I A ++G ++ +L+ G P+ + G T LH++ G E V+ L+ GA
Sbjct: 56 TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV-- 113
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKEL 204
++ + TPLH +A V+ L+ GA NA S +PLH + +V L
Sbjct: 114 -EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 172
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ GA TPLHVAA G LLL A AA G T LH+AA +
Sbjct: 173 LDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAA-GKSGLTPLHVAAHYDN 231
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LLLD GA G TPLH+A +++ L++ AD A G +H
Sbjct: 232 QKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 291
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A G D+ LLL A+ N ++ G TPLH+AA + +L++ G V +T
Sbjct: 292 AAQEG--HVDMVSLLLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK 349
Query: 385 GGVSAL 390
G + L
Sbjct: 350 MGYTPL 355
Score = 121 bits (291), Expect = 1e-26
Identities = 72/188 (38%), Positives = 97/188 (51%), Gaps = 3/188 (1%)
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
+LL+ A P+ + TPLH+A +LLL GA ++A G T +H+AA
Sbjct: 6 DLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESG-LTPIHVAAFM 64
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH L+ HGA + N RG+T LH+A + EVV LV A V AK D +TPL
Sbjct: 65 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPL 124
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H + G DI + LL GA PNAA GYTPLH++A LLD+G +++
Sbjct: 125 HISARLG--KADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSIT 182
Query: 383 TNGGVSAL 390
T G + L
Sbjct: 183 TKKGFTPL 190
Score = 84.2 bits (199), Expect = 2e-15
Identities = 68/229 (29%), Positives = 96/229 (41%), Gaps = 6/229 (2%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+A G GL + A + + + L LL G P G T LH++ + L
Sbjct: 213 DAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 271
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLS 195
L++GA N + T +H AA + V +L+ A+VN + S +PLH A
Sbjct: 272 LEYGADAN---AVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQE 328
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
D V + L+ GA D TPLHV G+ LL A V A G T
Sbjct: 329 DRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGY-TP 387
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LH AA+ GH +LL + A + G T L +A + VV+ L
Sbjct: 388 LHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 436
Score = 66.1 bits (154), Expect = 4e-10
Identities = 46/152 (30%), Positives = 65/152 (42%), Gaps = 2/152 (1%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
T LH+A + + LLL HGA I G TP+H+A + +V L+ A
Sbjct: 23 TPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNT 82
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ G T LH A R +A ++ R L+ GA A TPLHI+A + V LL
Sbjct: 83 TNVRGETALHMA-ARSGQA-EVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLL 140
Query: 374 DYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
G T G + L R + + +L
Sbjct: 141 QQGASPNAATTSGYTPLHLSAREGHEDVAAFL 172
Score = 46.8 bits (106), Expect = 3e-04
Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+D+ A+ AK +G TPLH A + + LLL GA A G TP+H+AA
Sbjct: 7 LLDKKANPNAKALNGFTPLHIACKKNR--IKVMELLLKHGASIQAVTESGLTPIHVAAFM 64
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
V L+ +G G +AL R + RYL
Sbjct: 65 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 106
>AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 169 bits (410), Expect = 4e-41
Identities = 109/289 (37%), Positives = 149/289 (51%), Gaps = 7/289 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL +P+ G T LH++C + ++LLL HGA + + TE+ TP+H AA
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGA---SIQAVTESGLTPIHVAAF 57
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V L+ HGA N + + LH A S EVV+ L++ GA + +TP
Sbjct: 58 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 117
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH++A LG A + LL GA AA G T LHL+A +GH + A LLDHGA +
Sbjct: 118 LHISARLGKADIVQQLLQQGASPNAATTSGY-TPLHLSAREGHEDVAAFLLDHGASLSIT 176
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLH+A LEV +L+ + A A G TPLH A + +A LLL
Sbjct: 177 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQ--KVALLLLD 234
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA P+AA GYTPLHIAA LL+YG D T G++++
Sbjct: 235 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 283
Score = 153 bits (370), Expect = 3e-36
Identities = 113/305 (37%), Positives = 146/305 (47%), Gaps = 13/305 (4%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LGK+ ++ +LL+ G P+ +G T LHLS G E+ LLDHGA + +T+
Sbjct: 124 LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA---SLSITTKKG 180
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
TPLH AA L +L+ A + AG S +PLH A D +V LL+ GA P
Sbjct: 181 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 240
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
TPLH+AA LL GAD A G A ++HLAA++GH + LLL
Sbjct: 241 AAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIA-SVHLAAQEGHVDMVSLLL 299
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
A N G TPLHLA + V E+LV++ A V A+ G TPLH G
Sbjct: 300 GRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG--N 352
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
I LL A NA GYTPLH AA + + +LL T G +AL
Sbjct: 353 IKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG- 411
Query: 393 IVRRV 397
I RR+
Sbjct: 412 IARRL 416
Score = 145 bits (351), Expect = 6e-34
Identities = 100/291 (34%), Positives = 141/291 (48%), Gaps = 7/291 (2%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC + ++ LLK G + ++G T +H++ +G V L+ HGA PNT +
Sbjct: 22 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 81
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
E T LH AA + V+ L+ GA V A D++PLH + ++V++LL+ GA
Sbjct: 82 E---TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 138
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
P+ TPLH++A G LL+ GA + G T LH+AA+ G E A
Sbjct: 139 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKG-FTPLHVAAKYGKLEVAN 197
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL A D G TPLH+A + +V +L+D+ A A +G TPLH I
Sbjct: 198 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLH--IAAK 255
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
DIA LL GAD NA G +H+AA V LLL +V+
Sbjct: 256 KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVS 306
Score = 136 bits (330), Expect = 2e-31
Identities = 90/262 (34%), Positives = 125/262 (47%), Gaps = 7/262 (2%)
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAVL 194
LLD A+PN + TPLH A + +++L+ HGA + A S +P+H A
Sbjct: 1 LLDKKANPN---AKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAF 57
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+V +L+ GA P+T V ET LH+AA G A + L+ GA V A + T
Sbjct: 58 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ-T 116
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH++A G A+ + LL GA + G TPLHL+ +V L+D A +
Sbjct: 117 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSIT 176
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G TPLH A G ++A LLL A P+AA G TPLH+AA + LLLLD
Sbjct: 177 TKKGFTPLHVAAKYGK--LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 234
Query: 375 YGGDVTLRTNGGVSALSFIVRR 396
G G + L ++
Sbjct: 235 QGASPHAAAKNGYTPLHIAAKK 256
Score = 123 bits (297), Expect = 2e-27
Identities = 96/306 (31%), Positives = 138/306 (45%), Gaps = 12/306 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T I A ++G ++ +L+ G P+ + G T LH++ G E V+ L+ GA
Sbjct: 50 TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV-- 107
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKEL 204
++ + TPLH +A V+ L+ GA NA S +PLH + +V L
Sbjct: 108 -EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 166
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ GA TPLHVAA G LLL A AA G T LH+AA +
Sbjct: 167 LDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAA-GKSGLTPLHVAAHYDN 225
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LLLD GA G TPLH+A +++ L++ AD A G +H
Sbjct: 226 QKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 285
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A G D+ LLL A+ + G TPLH+AA + +L++ G V +T
Sbjct: 286 AAQEG--HVDMVSLLLGRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK 338
Query: 385 GGVSAL 390
G + L
Sbjct: 339 MGYTPL 344
Score = 80.6 bits (190), Expect = 2e-14
Identities = 67/228 (29%), Positives = 94/228 (41%), Gaps = 9/228 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+A G GL + A + + + L LL G P G T LH++ + L
Sbjct: 207 DAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 265
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSD 196
L++GA N + T +H AA + V +L+ NA +S +PLH A D
Sbjct: 266 LEYGADAN---AVTRQGIASVHLAAQEGHVDMVSLLLGR----NANVSGLTPLHLAAQED 318
Query: 197 APEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
V + L+ GA D TPLHV G+ LL A V A G T L
Sbjct: 319 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGY-TPL 377
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
H AA+ GH +LL + A + G T L +A + VV+ L
Sbjct: 378 HQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 425
Score = 66.1 bits (154), Expect = 4e-10
Identities = 46/152 (30%), Positives = 65/152 (42%), Gaps = 2/152 (1%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
T LH+A + + LLL HGA I G TP+H+A + +V L+ A
Sbjct: 17 TPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNT 76
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ G T LH A R +A ++ R L+ GA A TPLHI+A + V LL
Sbjct: 77 TNVRGETALHMA-ARSGQA-EVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLL 134
Query: 374 DYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
G T G + L R + + +L
Sbjct: 135 QQGASPNAATTSGYTPLHLSAREGHEDVAAFL 166
Score = 46.8 bits (106), Expect = 3e-04
Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+D+ A+ AK +G TPLH A + + LLL GA A G TP+H+AA
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNR--IKVMELLLKHGASIQAVTESGLTPIHVAAFM 58
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
V L+ +G G +AL R + RYL
Sbjct: 59 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 100
>AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 169 bits (410), Expect = 4e-41
Identities = 109/289 (37%), Positives = 149/289 (51%), Gaps = 7/289 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL +P+ G T LH++C + ++LLL HGA + + TE+ TP+H AA
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGA---SIQAVTESGLTPIHVAAF 57
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V L+ HGA N + + LH A S EVV+ L++ GA + +TP
Sbjct: 58 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTP 117
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH++A LG A + LL GA AA G T LHL+A +GH + A LLDHGA +
Sbjct: 118 LHISARLGKADIVQQLLQQGASPNAATTSGY-TPLHLSAREGHEDVAAFLLDHGASLSIT 176
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLH+A LEV +L+ + A A G TPLH A + +A LLL
Sbjct: 177 TKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQ--KVALLLLD 234
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA P+AA GYTPLHIAA LL+YG D T G++++
Sbjct: 235 QGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASV 283
Score = 153 bits (370), Expect = 3e-36
Identities = 113/305 (37%), Positives = 146/305 (47%), Gaps = 13/305 (4%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LGK+ ++ +LL+ G P+ +G T LHLS G E+ LLDHGA + +T+
Sbjct: 124 LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA---SLSITTKKG 180
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
TPLH AA L +L+ A + AG S +PLH A D +V LL+ GA P
Sbjct: 181 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 240
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
TPLH+AA LL GAD A G A ++HLAA++GH + LLL
Sbjct: 241 AAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIA-SVHLAAQEGHVDMVSLLL 299
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
A N G TPLHLA + V E+LV++ A V A+ G TPLH G
Sbjct: 300 GRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG--N 352
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
I LL A NA GYTPLH AA + + +LL T G +AL
Sbjct: 353 IKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG- 411
Query: 393 IVRRV 397
I RR+
Sbjct: 412 IARRL 416
Score = 145 bits (351), Expect = 6e-34
Identities = 100/291 (34%), Positives = 141/291 (48%), Gaps = 7/291 (2%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC + ++ LLK G + ++G T +H++ +G V L+ HGA PNT +
Sbjct: 22 ACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRG 81
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
E T LH AA + V+ L+ GA V A D++PLH + ++V++LL+ GA
Sbjct: 82 E---TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 138
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
P+ TPLH++A G LL+ GA + G T LH+AA+ G E A
Sbjct: 139 SPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKG-FTPLHVAAKYGKLEVAN 197
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL A D G TPLH+A + +V +L+D+ A A +G TPLH I
Sbjct: 198 LLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLH--IAAK 255
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
DIA LL GAD NA G +H+AA V LLL +V+
Sbjct: 256 KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVS 306
Score = 136 bits (330), Expect = 2e-31
Identities = 90/262 (34%), Positives = 125/262 (47%), Gaps = 7/262 (2%)
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAVL 194
LLD A+PN + TPLH A + +++L+ HGA + A S +P+H A
Sbjct: 1 LLDKKANPN---AKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAF 57
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+V +L+ GA P+T V ET LH+AA G A + L+ GA V A + T
Sbjct: 58 MGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ-T 116
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH++A G A+ + LL GA + G TPLHL+ +V L+D A +
Sbjct: 117 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSIT 176
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G TPLH A G ++A LLL A P+AA G TPLH+AA + LLLLD
Sbjct: 177 TKKGFTPLHVAAKYGK--LEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLD 234
Query: 375 YGGDVTLRTNGGVSALSFIVRR 396
G G + L ++
Sbjct: 235 QGASPHAAAKNGYTPLHIAAKK 256
Score = 123 bits (297), Expect = 2e-27
Identities = 96/306 (31%), Positives = 138/306 (45%), Gaps = 12/306 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T I A ++G ++ +L+ G P+ + G T LH++ G E V+ L+ GA
Sbjct: 50 TPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQV-- 107
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKEL 204
++ + TPLH +A V+ L+ GA NA S +PLH + +V L
Sbjct: 108 -EAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 166
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ GA TPLHVAA G LLL A AA G T LH+AA +
Sbjct: 167 LDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAA-GKSGLTPLHVAAHYDN 225
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LLLD GA G TPLH+A +++ L++ AD A G +H
Sbjct: 226 QKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHL 285
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A G D+ LLL A+ + G TPLH+AA + +L++ G V +T
Sbjct: 286 AAQEG--HVDMVSLLLGRNANVS-----GLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTK 338
Query: 385 GGVSAL 390
G + L
Sbjct: 339 MGYTPL 344
Score = 80.6 bits (190), Expect = 2e-14
Identities = 67/228 (29%), Positives = 94/228 (41%), Gaps = 9/228 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+A G GL + A + + + L LL G P G T LH++ + L
Sbjct: 207 DAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 265
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSD 196
L++GA N + T +H AA + V +L+ NA +S +PLH A D
Sbjct: 266 LEYGADAN---AVTRQGIASVHLAAQEGHVDMVSLLLGR----NANVSGLTPLHLAAQED 318
Query: 197 APEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
V + L+ GA D TPLHV G+ LL A V A G T L
Sbjct: 319 RVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGY-TPL 377
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
H AA+ GH +LL + A + G T L +A + VV+ L
Sbjct: 378 HQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 425
Score = 66.1 bits (154), Expect = 4e-10
Identities = 46/152 (30%), Positives = 65/152 (42%), Gaps = 2/152 (1%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
T LH+A + + LLL HGA I G TP+H+A + +V L+ A
Sbjct: 17 TPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNT 76
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ G T LH A R +A ++ R L+ GA A TPLHI+A + V LL
Sbjct: 77 TNVRGETALHMA-ARSGQA-EVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLL 134
Query: 374 DYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
G T G + L R + + +L
Sbjct: 135 QQGASPNAATTSGYTPLHLSAREGHEDVAAFL 166
Score = 46.8 bits (106), Expect = 3e-04
Identities = 33/102 (32%), Positives = 45/102 (44%), Gaps = 2/102 (1%)
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+D+ A+ AK +G TPLH A + + LLL GA A G TP+H+AA
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNR--IKVMELLLKHGASIQAVTESGLTPIHVAAFM 58
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
V L+ +G G +AL R + RYL
Sbjct: 59 GHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYL 100
>AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1
variant protein.
Length = 931
Score = 160 bits (389), Expect = 1e-38
Identities = 113/305 (37%), Positives = 149/305 (48%), Gaps = 8/305 (2%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LGK+ ++ +LL+ G P+ +G T LHLS G E+ LLDHGA + +T+
Sbjct: 53 LGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGA---SLSITTKKG 109
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
TPLH AA L +L+ A + AG S +PLH A D +V LL+ GA P
Sbjct: 110 FTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 169
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
TPLH+AA LL GAD A G A ++HLAA++GH + LLL
Sbjct: 170 AAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIA-SVHLAAQEGHVDMVSLLL 228
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
A+++ N G TPLHLA + V E+LV++ A V A+ G TPLH G
Sbjct: 229 GRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYG--N 286
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
I LL A NA GYTPLH AA + + +LL T G +AL
Sbjct: 287 IKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALG- 345
Query: 393 IVRRV 397
I RR+
Sbjct: 346 IARRL 350
Score = 136 bits (330), Expect = 2e-31
Identities = 82/202 (40%), Positives = 107/202 (52%), Gaps = 3/202 (1%)
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH A S EVV+ L++ GA + +TPLH++A LG A + LL GA AA
Sbjct: 14 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAAT 73
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G T LHL+A +GH + A LLDHGA + +G TPLH+A LEV +L+ +
Sbjct: 74 TSGY-TPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKS 132
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
A A G TPLH A + +A LLL GA P+AA GYTPLHIAA
Sbjct: 133 ASPDAAGKSGLTPLHVAAHYDNQ--KVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDI 190
Query: 369 VLLLLDYGGDVTLRTNGGVSAL 390
LL+YG D T G++++
Sbjct: 191 ATTLLEYGADANAVTRQGIASV 212
Score = 133 bits (322), Expect = 2e-30
Identities = 96/306 (31%), Positives = 146/306 (47%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G++ ++ L++ G + +T LH+S +G + V+ LL GA PN
Sbjct: 12 TALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPN- 70
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKEL 204
++T + TPLH +A L+ HGA ++ +PLH A EV L
Sbjct: 71 --AATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 128
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ A PD TPLHVAA + LLL+ GA AA G T LH+AA+
Sbjct: 129 LQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNG-YTPLHIAAKKNQ 187
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A LL++GA + +G +HLA +++V +L+ R A+V + G TPLH
Sbjct: 188 MDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLH- 246
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
+ ++A +L++ GA +A GYTPLH+ V LL + V +T
Sbjct: 247 -LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTK 305
Query: 385 GGVSAL 390
G + L
Sbjct: 306 NGYTPL 311
Score = 123 bits (297), Expect = 2e-27
Identities = 90/275 (32%), Positives = 125/275 (45%), Gaps = 7/275 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G T LH++ G E V+ L+ GA ++ + TPLH +A V+ L+ G
Sbjct: 10 GETALHMAARSGQAEVVRYLVQDGAQV---EAKAKDDQTPLHISARLGKADIVQQLLQQG 66
Query: 177 ADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
A NA S +PLH + +V LL+ GA TPLHVAA G
Sbjct: 67 ASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVAN 126
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL A AA G T LH+AA + + A LLLD GA G TPLH+A
Sbjct: 127 LLLQKSASPDAA-GKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 185
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+++ L++ AD A G +H A G D+ LLL A+ N ++ G T
Sbjct: 186 NQMDIATTLLEYGADANAVTRQGIASVHLAAQEG--HVDMVSLLLGRNANVNLSNKSGLT 243
Query: 356 PLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
PLH+AA + +L++ G V +T G + L
Sbjct: 244 PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPL 278
Score = 96.7 bits (230), Expect = 3e-19
Identities = 63/178 (35%), Positives = 84/178 (47%), Gaps = 3/178 (1%)
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
ET LH+AA G A + L+ GA V A + T LH++A G A+ + LL GA
Sbjct: 11 ETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQ-TPLHISARLGKADIVQQLLQQGASP 69
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ G TPLHL+ +V L+D A + G TPLH A G ++A L
Sbjct: 70 NAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK--LEVANL 127
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
LL A P+AA G TPLH+AA + LLLLD G G + L ++
Sbjct: 128 LLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKK 185
Score = 84.2 bits (199), Expect = 2e-15
Identities = 68/229 (29%), Positives = 96/229 (41%), Gaps = 6/229 (2%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+A G GL + A + + + L LL G P G T LH++ + L
Sbjct: 136 DAAGKSGLTPLHVAAHYDNQKVALL-LLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTL 194
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLS 195
L++GA N + T +H AA + V +L+ A+VN + S +PLH A
Sbjct: 195 LEYGADAN---AVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHLAAQE 251
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
D V + L+ GA D TPLHV G+ LL A V A G T
Sbjct: 252 DRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGY-TP 310
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LH AA+ GH +LL + A + G T L +A + VV+ L
Sbjct: 311 LHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTL 359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 45/107 (42%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAG 343
RG+T LH+A + EVV LV A V AK D +TPLH + G DI + LL G
Sbjct: 9 RGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLG--KADIVQQLLQQG 66
Query: 344 ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A PNAA GYTPLH++A LLD+G +++ T G + L
Sbjct: 67 ASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPL 113
Score = 34.3 bits (75), Expect = 1.6
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 2/88 (2%)
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G T LH A R +A ++ R L+ GA A TPLHI+A + V LL G
Sbjct: 10 GETALHMA-ARSGQA-EVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGA 67
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYL 405
T G + L R + + +L
Sbjct: 68 SPNAATTSGYTPLHLSAREGHEDVAAFL 95
>BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 157 bits (380), Expect = 2e-37
Identities = 109/310 (35%), Positives = 151/310 (48%), Gaps = 8/310 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A + G ++ LL G + + D R +H + +G E VKLL+ HGA
Sbjct: 174 RTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 233
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + TPLH AAS+ ++ VK L+ G D+N +PLH A + VV E
Sbjct: 234 CKDKKS---YTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNE 290
Query: 204 LLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L++ GA + TPLH AAS A C +LL+ GADV GK T LH+ A
Sbjct: 291 LIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGK-TPLHMTALH 349
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G ++ ++ GA ID + G TPLH+A ++ L+ AD + G PL
Sbjct: 350 GRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPL 409
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A + G C R LLS+G D + D+FG T LH AA C+ LLL+ G D +
Sbjct: 410 HLAALSGFSDC--CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 467
Query: 383 TNGGVSALSF 392
G S L +
Sbjct: 468 DKFGRSPLHY 477
Score = 157 bits (380), Expect = 2e-37
Identities = 106/293 (36%), Positives = 148/293 (50%), Gaps = 9/293 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH-CAA 161
LL +GVD +E + G T LH++C G + V L+D GA N E TPLH AA
Sbjct: 258 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVN---QKNEKGFTPLHFAAA 314
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
S C+++L+ +GADVN D ++PLH L + ++++GA D T
Sbjct: 315 STHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNT 374
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G L+ +GAD A G LHLAA G ++C R LL G ID
Sbjct: 375 PLHIAARYGHELLINTLITSGADT-AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 433
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P+ G+T LH A +LE + +L++ AD KD GR+PLH A C A L+
Sbjct: 434 PDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA--LV 491
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA-CVLLLLDYGGDVTLRTNGGVSALSF 392
+GA N D G TPLH AA ++ C+ LL + +R G +A+ +
Sbjct: 492 GSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHY 544
Score = 145 bits (352), Expect = 4e-34
Identities = 100/279 (35%), Positives = 139/279 (49%), Gaps = 8/279 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D AGRT LH + G E VKLLL GA+ N +D + +A +H AA + VK+L+
Sbjct: 170 DRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKK-DRRA--IHWAAYMGHIEVVKLLV 226
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
+HGA+V +PLH A S VVK LL+ G + P + TPLHVA G
Sbjct: 227 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDV 286
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGH-AECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ GA V G T LH AA H A C LL+ +GA ++ + G+TPLH+
Sbjct: 287 VVNELIDCGAIVNQKNEKG-FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHM 345
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
L + ++ A + +D +G TPLH A G + L+++GAD
Sbjct: 346 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHEL--LINTLITSGADTAKRGI 403
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G PLH+AAL+ FS C LL G D+ + G + L
Sbjct: 404 HGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCL 442
Score = 138 bits (334), Expect = 7e-32
Identities = 105/307 (34%), Positives = 152/307 (49%), Gaps = 24/307 (7%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
KLL G D D DD GRTCLH + G+ EC+ LLL+ GA N D + +PLH AA
Sbjct: 423 KLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD---KFGRSPLHYAA 479
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAP-EVVKELLEAGACPDTPQVFT 218
+ + C+ L+ GA VN L +R +PLHYA SD + ++ LL A P
Sbjct: 480 ANCNYQCLFALVGSGASVN-DLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQG 538
Query: 219 ETPLHVAASLGSASCTKLLLN----------AGADVRA-AMGPGKATALHLAAEDGHAEC 267
+H +A+ G C +L+ + +G D+ + + + LHLAA GH +
Sbjct: 539 YNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQA 598
Query: 268 ARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD-ADGRTPLHGAI 326
+L+ +D N G+TPL LA +E V++L+++ A + KD RTP+H A
Sbjct: 599 LEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAA 658
Query: 327 VRGARACDIARLLLSAGADPNAA---DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G C RLL+ NA D G TPL ++ LN + CV LL+ G +V +
Sbjct: 659 TNGHSEC--LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKD 716
Query: 384 NGGVSAL 390
G +AL
Sbjct: 717 KWGRTAL 723
Score = 137 bits (331), Expect = 2e-31
Identities = 103/312 (33%), Positives = 148/312 (47%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D T LH + SEE V++LL H A N
Sbjct: 75 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C + L+ ++VN + + R+ LH+A S E+VK
Sbjct: 135 ARDKNWQ---TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 191
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + +H AA +G KLL++ GA+V T LH AA G
Sbjct: 192 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV-TCKDKKSYTPLHAAASSG 250
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LLD G ++ PN G TPLH+A VV L+D A V K+ G TPLH
Sbjct: 251 MISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 310
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL+ GAD N G TPLH+ AL+ + ++ G +
Sbjct: 311 FAAASTHGALCL-ELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCED 369
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 370 KNGNTPLHIAAR 381
Score = 135 bits (327), Expect = 5e-31
Identities = 88/241 (36%), Positives = 125/241 (51%), Gaps = 4/241 (1%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACP 211
K TPLH AA +++LI GA VNA S +PLH AV S + E V+ LL+ A
Sbjct: 74 KRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADV 133
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ +TPLH+AA+ + C + L+ ++V + G+ TALH AA GH E +LL
Sbjct: 134 NARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR-TALHHAAFSGHGEMVKLL 192
Query: 272 LDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGAR 331
L GA+I+ + + + +H A +EVV++LV A+V KD TPLH A G
Sbjct: 193 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM- 251
Query: 332 ACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
+ + LL G D N + +G TPLH+A N V L+D G V + G + L
Sbjct: 252 -ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 310
Query: 392 F 392
F
Sbjct: 311 F 311
Score = 114 bits (274), Expect = 1e-24
Identities = 100/358 (27%), Positives = 157/358 (43%), Gaps = 11/358 (3%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCL-VGSEECVKLLLDHGAHPNTWDSS 149
AC+ G+ +++ +L+ G ++ ++ G T LH + C++LL+ +GA N S
Sbjct: 279 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNM--KS 336
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAG 208
+ K TPLH A + + +I GA ++ + +PLH A ++ L+ +G
Sbjct: 337 KDGK-TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSG 395
Query: 209 ACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECA 268
A + PLH+AA G + C + LL++G D+ G+ T LH AA G+ EC
Sbjct: 396 ADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGR-TCLHAAAAGGNLECL 454
Query: 269 RLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVR 328
LLL+ GA + + G++PLH A + + + LV A V D G TPLH A
Sbjct: 455 NLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATS 514
Query: 329 GARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVS 388
LL A+P D GY +H +A C+ L+ L G
Sbjct: 515 DTDG-KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 573
Query: 389 ALSFIVRRVPDVIPRYLCKF---DDAVHVSEHELGDVDCELTIDFRPLVPCLTRGEAE 443
LS R + P +L + A+ V L D+D + PL +G E
Sbjct: 574 MLSDSDNRA-TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 630
Score = 111 bits (268), Expect = 7e-24
Identities = 89/276 (32%), Positives = 135/276 (48%), Gaps = 16/276 (5%)
Query: 100 LFKLLKMGVDPDELDDAGRTCLHLSCLVGSE-ECVKLLLDHGAHPNTWD----SSTETKA 154
LF L+ G ++LD+ G T LH + ++ +C++ LL + A+P D ++ A
Sbjct: 487 LFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSA 546
Query: 155 TPLH--CAASAKSLACVKVLI-AHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAG 208
H C S + VL+ G D+ + +R SPLH A + ++ L+++
Sbjct: 547 AYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSL 606
Query: 209 ACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECA 268
D TPL +AA G C +L+N GA + K T +H AA +GH+EC
Sbjct: 607 LDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECL 666
Query: 269 RLLLDHGAH---IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
RLL+ + +D + GQTPL L+ L + V L+++ A+V AKD GRT LH
Sbjct: 667 RLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRG 726
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAA 361
V G C A LL GA D+ G TP+H++A
Sbjct: 727 AVTGHEECVDA--LLQHGAKCLLRDSRGRTPIHLSA 760
Score = 110 bits (265), Expect = 2e-23
Identities = 99/333 (29%), Positives = 158/333 (47%), Gaps = 29/333 (8%)
Query: 74 FASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECV 133
F + FG RT + A G L LL G D ++ D GR+ LH + + +C+
Sbjct: 429 FDIDTPDDFG-RTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCL 487
Query: 134 KLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA-CVKVLIAHGADVNAGLSDR---SPL 189
L+ GA N D E TPLH AA++ + C++ L+ + D N G+ D+ + +
Sbjct: 488 FALVGSGASVNDLD---ERGCTPLHYAATSDTDGKCLEYLLRN--DANPGIRDKQGYNAV 542
Query: 190 HYA-----------VLSDAP-EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
HY+ + S+ P +V+ E D+ T +PLH+AA G ++L
Sbjct: 543 HYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVL 602
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF-RGQTPLHLATLAQ 296
+ + D+ G+ T L LAA GH EC +L++ GA I ++ +TP+H A
Sbjct: 603 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNG 661
Query: 297 SLEVVEMLVDRCADVRA---KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFG 353
E + +L+ A +D +G+TPL +++ G C + LL+ GA+ +A D +G
Sbjct: 662 HSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYS--LLNKGANVDAKDKWG 719
Query: 354 YTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
T LH A+ CV LL +G LR + G
Sbjct: 720 RTALHRGAVTGHEECVDALLQHGAKCLLRDSRG 752
Score = 99 bits (238), Expect = 3e-20
Identities = 70/212 (33%), Positives = 109/212 (51%), Gaps = 4/212 (1%)
Query: 169 VKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
V+ LI DVN ++ R+PLH A E+++ L+ +GA + TPLH A +
Sbjct: 57 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 116
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
S ++LL ADV A T LH+AA + +CA L+ ++++ + G+T
Sbjct: 117 SCSEEAVQVLLKHSADVNAR-DKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRT 175
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LH A + E+V++L+ R A++ A D R +H A G ++ +LL+S GA+
Sbjct: 176 ALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMG--HIEVVKLLVSHGAEVT 233
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
D YTPLH AA + + V LLD G D+
Sbjct: 234 CKDKKSYTPLHAAASSGMISVVKYLLDLGVDM 265
Score = 90.6 bits (215), Expect = 2e-17
Identities = 78/260 (30%), Positives = 118/260 (45%), Gaps = 13/260 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL-----LDHGAHPNTWD--SSTETKAT 155
LL+ +P D G +H S G C++L+ LD + D S ++ +AT
Sbjct: 524 LLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRAT 583
Query: 156 --PLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
PLH AA ++VL+ D++ S R+PL A E V L+ GA
Sbjct: 584 ISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 643
Query: 213 TPQ-VFTETPLHVAASLGSASCTKLLL-NAGADVRAAMGPGKA-TALHLAAEDGHAECAR 269
+ TP+H AA+ G + C +LL+ NA + G T L L+ +GH +C
Sbjct: 644 VKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVY 703
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA++D + G+T LH + E V+ L+ A +D+ GRTP+H + G
Sbjct: 704 SLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACG 763
Query: 330 ARACDIARLLLSAGADPNAA 349
A L +A D N A
Sbjct: 764 HIGVLGALLQSAASMDANPA 783
Score = 67.7 bits (158), Expect = 1e-10
Identities = 42/129 (32%), Positives = 65/129 (50%), Gaps = 2/129 (1%)
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+G + R L+ +++ + +TPLH A E++E+L+ A V AKD+ TP
Sbjct: 51 NGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTP 110
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
LH A+ + + ++LL AD NA D TPLHIAA N+ C L+ +V +
Sbjct: 111 LHRAVASCSE--EAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 168
Query: 382 RTNGGVSAL 390
G +AL
Sbjct: 169 SDRAGRTAL 177
Score = 58.8 bits (136), Expect = 7e-08
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 8/127 (6%)
Query: 55 YSEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELD 114
+SE + +LIGN Q A + + G G +T ++ + G + ++ LL G + D D
Sbjct: 662 HSECLRLLIGNAEP----QNAVDIQDGNG-QTPLMLSVLNGHTDCVYSLLNKGANVDAKD 716
Query: 115 DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIA 174
GRT LH + G EECV LL HGA DS TP+H +A+ + + L+
Sbjct: 717 KWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGR---TPIHLSAACGHIGVLGALLQ 773
Query: 175 HGADVNA 181
A ++A
Sbjct: 774 SAASMDA 780
>BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein.
Length = 782
Score = 157 bits (380), Expect = 2e-37
Identities = 109/310 (35%), Positives = 151/310 (48%), Gaps = 8/310 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A + G ++ LL G + + D R +H + +G E VKLL+ HGA
Sbjct: 171 RTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 230
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + TPLH AAS+ ++ VK L+ G D+N +PLH A + VV E
Sbjct: 231 CKDKKS---YTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNE 287
Query: 204 LLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L++ GA + TPLH AAS A C +LL+ GADV GK T LH+ A
Sbjct: 288 LIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGK-TPLHMTALH 346
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G ++ ++ GA ID + G TPLH+A ++ L+ AD + G PL
Sbjct: 347 GRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPL 406
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A + G C R LLS+G D + D+FG T LH AA C+ LLL+ G D +
Sbjct: 407 HLAALSGFSDC--CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 464
Query: 383 TNGGVSALSF 392
G S L +
Sbjct: 465 DKFGRSPLHY 474
Score = 157 bits (380), Expect = 2e-37
Identities = 106/293 (36%), Positives = 148/293 (50%), Gaps = 9/293 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH-CAA 161
LL +GVD +E + G T LH++C G + V L+D GA N E TPLH AA
Sbjct: 255 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVN---QKNEKGFTPLHFAAA 311
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
S C+++L+ +GADVN D ++PLH L + ++++GA D T
Sbjct: 312 STHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNT 371
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G L+ +GAD A G LHLAA G ++C R LL G ID
Sbjct: 372 PLHIAARYGHELLINTLITSGADT-AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 430
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P+ G+T LH A +LE + +L++ AD KD GR+PLH A C A L+
Sbjct: 431 PDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA--LV 488
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA-CVLLLLDYGGDVTLRTNGGVSALSF 392
+GA N D G TPLH AA ++ C+ LL + +R G +A+ +
Sbjct: 489 GSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHY 541
Score = 145 bits (352), Expect = 4e-34
Identities = 100/279 (35%), Positives = 139/279 (49%), Gaps = 8/279 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D AGRT LH + G E VKLLL GA+ N +D + +A +H AA + VK+L+
Sbjct: 167 DRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKK-DRRA--IHWAAYMGHIEVVKLLV 223
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
+HGA+V +PLH A S VVK LL+ G + P + TPLHVA G
Sbjct: 224 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDV 283
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGH-AECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ GA V G T LH AA H A C LL+ +GA ++ + G+TPLH+
Sbjct: 284 VVNELIDCGAIVNQKNEKG-FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHM 342
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
L + ++ A + +D +G TPLH A G + L+++GAD
Sbjct: 343 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHEL--LINTLITSGADTAKRGI 400
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G PLH+AAL+ FS C LL G D+ + G + L
Sbjct: 401 HGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCL 439
Score = 138 bits (334), Expect = 7e-32
Identities = 105/307 (34%), Positives = 152/307 (49%), Gaps = 24/307 (7%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
KLL G D D DD GRTCLH + G+ EC+ LLL+ GA N D + +PLH AA
Sbjct: 420 KLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD---KFGRSPLHYAA 476
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAP-EVVKELLEAGACPDTPQVFT 218
+ + C+ L+ GA VN L +R +PLHYA SD + ++ LL A P
Sbjct: 477 ANCNYQCLFALVGSGASVN-DLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQG 535
Query: 219 ETPLHVAASLGSASCTKLLLN----------AGADVRA-AMGPGKATALHLAAEDGHAEC 267
+H +A+ G C +L+ + +G D+ + + + LHLAA GH +
Sbjct: 536 YNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQA 595
Query: 268 ARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD-ADGRTPLHGAI 326
+L+ +D N G+TPL LA +E V++L+++ A + KD RTP+H A
Sbjct: 596 LEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAA 655
Query: 327 VRGARACDIARLLLSAGADPNAA---DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G C RLL+ NA D G TPL ++ LN + CV LL+ G +V +
Sbjct: 656 TNGHSEC--LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKD 713
Query: 384 NGGVSAL 390
G +AL
Sbjct: 714 KWGRTAL 720
Score = 137 bits (331), Expect = 2e-31
Identities = 103/312 (33%), Positives = 148/312 (47%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D T LH + SEE V++LL H A N
Sbjct: 72 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 131
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C + L+ ++VN + + R+ LH+A S E+VK
Sbjct: 132 ARDKNWQ---TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 188
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + +H AA +G KLL++ GA+V T LH AA G
Sbjct: 189 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV-TCKDKKSYTPLHAAASSG 247
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LLD G ++ PN G TPLH+A VV L+D A V K+ G TPLH
Sbjct: 248 MISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 307
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL+ GAD N G TPLH+ AL+ + ++ G +
Sbjct: 308 FAAASTHGALCL-ELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCED 366
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 367 KNGNTPLHIAAR 378
Score = 135 bits (327), Expect = 5e-31
Identities = 88/241 (36%), Positives = 125/241 (51%), Gaps = 4/241 (1%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACP 211
K TPLH AA +++LI GA VNA S +PLH AV S + E V+ LL+ A
Sbjct: 71 KRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADV 130
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ +TPLH+AA+ + C + L+ ++V + G+ TALH AA GH E +LL
Sbjct: 131 NARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR-TALHHAAFSGHGEMVKLL 189
Query: 272 LDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGAR 331
L GA+I+ + + + +H A +EVV++LV A+V KD TPLH A G
Sbjct: 190 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM- 248
Query: 332 ACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
+ + LL G D N + +G TPLH+A N V L+D G V + G + L
Sbjct: 249 -ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 307
Query: 392 F 392
F
Sbjct: 308 F 308
Score = 114 bits (274), Expect = 1e-24
Identities = 100/358 (27%), Positives = 157/358 (43%), Gaps = 11/358 (3%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCL-VGSEECVKLLLDHGAHPNTWDSS 149
AC+ G+ +++ +L+ G ++ ++ G T LH + C++LL+ +GA N S
Sbjct: 276 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNM--KS 333
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAG 208
+ K TPLH A + + +I GA ++ + +PLH A ++ L+ +G
Sbjct: 334 KDGK-TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSG 392
Query: 209 ACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECA 268
A + PLH+AA G + C + LL++G D+ G+ T LH AA G+ EC
Sbjct: 393 ADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGR-TCLHAAAAGGNLECL 451
Query: 269 RLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVR 328
LLL+ GA + + G++PLH A + + + LV A V D G TPLH A
Sbjct: 452 NLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATS 511
Query: 329 GARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVS 388
LL A+P D GY +H +A C+ L+ L G
Sbjct: 512 DTDG-KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 570
Query: 389 ALSFIVRRVPDVIPRYLCKF---DDAVHVSEHELGDVDCELTIDFRPLVPCLTRGEAE 443
LS R + P +L + A+ V L D+D + PL +G E
Sbjct: 571 MLSDSDNRA-TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 627
Score = 111 bits (268), Expect = 7e-24
Identities = 89/276 (32%), Positives = 135/276 (48%), Gaps = 16/276 (5%)
Query: 100 LFKLLKMGVDPDELDDAGRTCLHLSCLVGSE-ECVKLLLDHGAHPNTWD----SSTETKA 154
LF L+ G ++LD+ G T LH + ++ +C++ LL + A+P D ++ A
Sbjct: 484 LFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSA 543
Query: 155 TPLH--CAASAKSLACVKVLI-AHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAG 208
H C S + VL+ G D+ + +R SPLH A + ++ L+++
Sbjct: 544 AYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSL 603
Query: 209 ACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECA 268
D TPL +AA G C +L+N GA + K T +H AA +GH+EC
Sbjct: 604 LDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECL 663
Query: 269 RLLLDHGAH---IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
RLL+ + +D + GQTPL L+ L + V L+++ A+V AKD GRT LH
Sbjct: 664 RLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRG 723
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAA 361
V G C A LL GA D+ G TP+H++A
Sbjct: 724 AVTGHEECVDA--LLQHGAKCLLRDSRGRTPIHLSA 757
Score = 110 bits (265), Expect = 2e-23
Identities = 99/333 (29%), Positives = 158/333 (47%), Gaps = 29/333 (8%)
Query: 74 FASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECV 133
F + FG RT + A G L LL G D ++ D GR+ LH + + +C+
Sbjct: 426 FDIDTPDDFG-RTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCL 484
Query: 134 KLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA-CVKVLIAHGADVNAGLSDR---SPL 189
L+ GA N D E TPLH AA++ + C++ L+ + D N G+ D+ + +
Sbjct: 485 FALVGSGASVNDLD---ERGCTPLHYAATSDTDGKCLEYLLRN--DANPGIRDKQGYNAV 539
Query: 190 HYA-----------VLSDAP-EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
HY+ + S+ P +V+ E D+ T +PLH+AA G ++L
Sbjct: 540 HYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVL 599
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF-RGQTPLHLATLAQ 296
+ + D+ G+ T L LAA GH EC +L++ GA I ++ +TP+H A
Sbjct: 600 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNG 658
Query: 297 SLEVVEMLVDRCADVRA---KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFG 353
E + +L+ A +D +G+TPL +++ G C + LL+ GA+ +A D +G
Sbjct: 659 HSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYS--LLNKGANVDAKDKWG 716
Query: 354 YTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
T LH A+ CV LL +G LR + G
Sbjct: 717 RTALHRGAVTGHEECVDALLQHGAKCLLRDSRG 749
Score = 99 bits (238), Expect = 3e-20
Identities = 70/212 (33%), Positives = 109/212 (51%), Gaps = 4/212 (1%)
Query: 169 VKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
V+ LI DVN ++ R+PLH A E+++ L+ +GA + TPLH A +
Sbjct: 54 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 113
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
S ++LL ADV A T LH+AA + +CA L+ ++++ + G+T
Sbjct: 114 SCSEEAVQVLLKHSADVNAR-DKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRT 172
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LH A + E+V++L+ R A++ A D R +H A G ++ +LL+S GA+
Sbjct: 173 ALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMG--HIEVVKLLVSHGAEVT 230
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
D YTPLH AA + + V LLD G D+
Sbjct: 231 CKDKKSYTPLHAAASSGMISVVKYLLDLGVDM 262
Score = 90.6 bits (215), Expect = 2e-17
Identities = 78/260 (30%), Positives = 118/260 (45%), Gaps = 13/260 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL-----LDHGAHPNTWD--SSTETKAT 155
LL+ +P D G +H S G C++L+ LD + D S ++ +AT
Sbjct: 521 LLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRAT 580
Query: 156 --PLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
PLH AA ++VL+ D++ S R+PL A E V L+ GA
Sbjct: 581 ISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 640
Query: 213 TPQ-VFTETPLHVAASLGSASCTKLLL-NAGADVRAAMGPGKA-TALHLAAEDGHAECAR 269
+ TP+H AA+ G + C +LL+ NA + G T L L+ +GH +C
Sbjct: 641 VKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVY 700
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA++D + G+T LH + E V+ L+ A +D+ GRTP+H + G
Sbjct: 701 SLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACG 760
Query: 330 ARACDIARLLLSAGADPNAA 349
A L +A D N A
Sbjct: 761 HIGVLGALLQSAASMDANPA 780
Score = 67.7 bits (158), Expect = 1e-10
Identities = 42/129 (32%), Positives = 65/129 (50%), Gaps = 2/129 (1%)
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+G + R L+ +++ + +TPLH A E++E+L+ A V AKD+ TP
Sbjct: 48 NGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTP 107
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
LH A+ + + ++LL AD NA D TPLHIAA N+ C L+ +V +
Sbjct: 108 LHRAVASCSE--EAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 165
Query: 382 RTNGGVSAL 390
G +AL
Sbjct: 166 SDRAGRTAL 174
Score = 58.8 bits (136), Expect = 7e-08
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 8/127 (6%)
Query: 55 YSEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELD 114
+SE + +LIGN Q A + + G G +T ++ + G + ++ LL G + D D
Sbjct: 659 HSECLRLLIGNAEP----QNAVDIQDGNG-QTPLMLSVLNGHTDCVYSLLNKGANVDAKD 713
Query: 115 DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIA 174
GRT LH + G EECV LL HGA DS TP+H +A+ + + L+
Sbjct: 714 KWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGR---TPIHLSAACGHIGVLGALLQ 770
Query: 175 HGADVNA 181
A ++A
Sbjct: 771 SAASMDA 777
>BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 157 bits (380), Expect = 2e-37
Identities = 109/310 (35%), Positives = 151/310 (48%), Gaps = 8/310 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A + G ++ LL G + + D R +H + +G E VKLL+ HGA
Sbjct: 174 RTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 233
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + TPLH AAS+ ++ VK L+ G D+N +PLH A + VV E
Sbjct: 234 CKDKKS---YTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNE 290
Query: 204 LLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L++ GA + TPLH AAS A C +LL+ GADV GK T LH+ A
Sbjct: 291 LIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGK-TPLHMTALH 349
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G ++ ++ GA ID + G TPLH+A ++ L+ AD + G PL
Sbjct: 350 GRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPL 409
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A + G C R LLS+G D + D+FG T LH AA C+ LLL+ G D +
Sbjct: 410 HLAALSGFSDC--CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 467
Query: 383 TNGGVSALSF 392
G S L +
Sbjct: 468 DKFGRSPLHY 477
Score = 157 bits (380), Expect = 2e-37
Identities = 106/293 (36%), Positives = 148/293 (50%), Gaps = 9/293 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH-CAA 161
LL +GVD +E + G T LH++C G + V L+D GA N E TPLH AA
Sbjct: 258 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVN---QKNEKGFTPLHFAAA 314
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
S C+++L+ +GADVN D ++PLH L + ++++GA D T
Sbjct: 315 STHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNT 374
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G L+ +GAD A G LHLAA G ++C R LL G ID
Sbjct: 375 PLHIAARYGHELLINTLITSGADT-AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 433
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P+ G+T LH A +LE + +L++ AD KD GR+PLH A C A L+
Sbjct: 434 PDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA--LV 491
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA-CVLLLLDYGGDVTLRTNGGVSALSF 392
+GA N D G TPLH AA ++ C+ LL + +R G +A+ +
Sbjct: 492 GSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHY 544
Score = 145 bits (352), Expect = 4e-34
Identities = 100/279 (35%), Positives = 139/279 (49%), Gaps = 8/279 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D AGRT LH + G E VKLLL GA+ N +D + +A +H AA + VK+L+
Sbjct: 170 DRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKK-DRRA--IHWAAYMGHIEVVKLLV 226
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
+HGA+V +PLH A S VVK LL+ G + P + TPLHVA G
Sbjct: 227 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDV 286
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGH-AECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ GA V G T LH AA H A C LL+ +GA ++ + G+TPLH+
Sbjct: 287 VVNELIDCGAIVNQKNEKG-FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHM 345
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
L + ++ A + +D +G TPLH A G + L+++GAD
Sbjct: 346 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHEL--LINTLITSGADTAKRGI 403
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G PLH+AAL+ FS C LL G D+ + G + L
Sbjct: 404 HGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCL 442
Score = 138 bits (334), Expect = 7e-32
Identities = 105/307 (34%), Positives = 152/307 (49%), Gaps = 24/307 (7%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
KLL G D D DD GRTCLH + G+ EC+ LLL+ GA N D + +PLH AA
Sbjct: 423 KLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD---KFGRSPLHYAA 479
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAP-EVVKELLEAGACPDTPQVFT 218
+ + C+ L+ GA VN L +R +PLHYA SD + ++ LL A P
Sbjct: 480 ANCNYQCLFALVGSGASVN-DLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQG 538
Query: 219 ETPLHVAASLGSASCTKLLLN----------AGADVRA-AMGPGKATALHLAAEDGHAEC 267
+H +A+ G C +L+ + +G D+ + + + LHLAA GH +
Sbjct: 539 YNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQA 598
Query: 268 ARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD-ADGRTPLHGAI 326
+L+ +D N G+TPL LA +E V++L+++ A + KD RTP+H A
Sbjct: 599 LEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAA 658
Query: 327 VRGARACDIARLLLSAGADPNAA---DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G C RLL+ NA D G TPL ++ LN + CV LL+ G +V +
Sbjct: 659 TNGHSEC--LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKD 716
Query: 384 NGGVSAL 390
G +AL
Sbjct: 717 KWGRTAL 723
Score = 137 bits (331), Expect = 2e-31
Identities = 103/312 (33%), Positives = 148/312 (47%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D T LH + SEE V++LL H A N
Sbjct: 75 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C + L+ ++VN + + R+ LH+A S E+VK
Sbjct: 135 ARDKNWQ---TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 191
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + +H AA +G KLL++ GA+V T LH AA G
Sbjct: 192 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV-TCKDKKSYTPLHAAASSG 250
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LLD G ++ PN G TPLH+A VV L+D A V K+ G TPLH
Sbjct: 251 MISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 310
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL+ GAD N G TPLH+ AL+ + ++ G +
Sbjct: 311 FAAASTHGALCL-ELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCED 369
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 370 KNGNTPLHIAAR 381
Score = 135 bits (327), Expect = 5e-31
Identities = 88/241 (36%), Positives = 125/241 (51%), Gaps = 4/241 (1%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACP 211
K TPLH AA +++LI GA VNA S +PLH AV S + E V+ LL+ A
Sbjct: 74 KRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADV 133
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ +TPLH+AA+ + C + L+ ++V + G+ TALH AA GH E +LL
Sbjct: 134 NARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR-TALHHAAFSGHGEMVKLL 192
Query: 272 LDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGAR 331
L GA+I+ + + + +H A +EVV++LV A+V KD TPLH A G
Sbjct: 193 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM- 251
Query: 332 ACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
+ + LL G D N + +G TPLH+A N V L+D G V + G + L
Sbjct: 252 -ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 310
Query: 392 F 392
F
Sbjct: 311 F 311
Score = 114 bits (274), Expect = 1e-24
Identities = 100/358 (27%), Positives = 157/358 (43%), Gaps = 11/358 (3%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCL-VGSEECVKLLLDHGAHPNTWDSS 149
AC+ G+ +++ +L+ G ++ ++ G T LH + C++LL+ +GA N S
Sbjct: 279 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNM--KS 336
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAG 208
+ K TPLH A + + +I GA ++ + +PLH A ++ L+ +G
Sbjct: 337 KDGK-TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSG 395
Query: 209 ACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECA 268
A + PLH+AA G + C + LL++G D+ G+ T LH AA G+ EC
Sbjct: 396 ADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGR-TCLHAAAAGGNLECL 454
Query: 269 RLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVR 328
LLL+ GA + + G++PLH A + + + LV A V D G TPLH A
Sbjct: 455 NLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATS 514
Query: 329 GARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVS 388
LL A+P D GY +H +A C+ L+ L G
Sbjct: 515 DTDG-KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 573
Query: 389 ALSFIVRRVPDVIPRYLCKF---DDAVHVSEHELGDVDCELTIDFRPLVPCLTRGEAE 443
LS R + P +L + A+ V L D+D + PL +G E
Sbjct: 574 MLSDSDNRA-TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 630
Score = 111 bits (268), Expect = 7e-24
Identities = 89/276 (32%), Positives = 135/276 (48%), Gaps = 16/276 (5%)
Query: 100 LFKLLKMGVDPDELDDAGRTCLHLSCLVGSE-ECVKLLLDHGAHPNTWD----SSTETKA 154
LF L+ G ++LD+ G T LH + ++ +C++ LL + A+P D ++ A
Sbjct: 487 LFALVGSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSA 546
Query: 155 TPLH--CAASAKSLACVKVLI-AHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAG 208
H C S + VL+ G D+ + +R SPLH A + ++ L+++
Sbjct: 547 AYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSL 606
Query: 209 ACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECA 268
D TPL +AA G C +L+N GA + K T +H AA +GH+EC
Sbjct: 607 LDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECL 666
Query: 269 RLLLDHGAH---IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
RLL+ + +D + GQTPL L+ L + V L+++ A+V AKD GRT LH
Sbjct: 667 RLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRG 726
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAA 361
V G C A LL GA D+ G TP+H++A
Sbjct: 727 AVTGHEECVDA--LLQHGAKCLLRDSRGRTPIHLSA 760
Score = 110 bits (265), Expect = 2e-23
Identities = 99/333 (29%), Positives = 158/333 (47%), Gaps = 29/333 (8%)
Query: 74 FASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECV 133
F + FG RT + A G L LL G D ++ D GR+ LH + + +C+
Sbjct: 429 FDIDTPDDFG-RTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCL 487
Query: 134 KLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA-CVKVLIAHGADVNAGLSDR---SPL 189
L+ GA N D E TPLH AA++ + C++ L+ + D N G+ D+ + +
Sbjct: 488 FALVGSGASVNDLD---ERGCTPLHYAATSDTDGKCLEYLLRN--DANPGIRDKQGYNAV 542
Query: 190 HYA-----------VLSDAP-EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
HY+ + S+ P +V+ E D+ T +PLH+AA G ++L
Sbjct: 543 HYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVL 602
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF-RGQTPLHLATLAQ 296
+ + D+ G+ T L LAA GH EC +L++ GA I ++ +TP+H A
Sbjct: 603 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNG 661
Query: 297 SLEVVEMLVDRCADVRA---KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFG 353
E + +L+ A +D +G+TPL +++ G C + LL+ GA+ +A D +G
Sbjct: 662 HSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYS--LLNKGANVDAKDKWG 719
Query: 354 YTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
T LH A+ CV LL +G LR + G
Sbjct: 720 RTALHRGAVTGHEECVDALLQHGAKCLLRDSRG 752
Score = 99 bits (238), Expect = 3e-20
Identities = 70/212 (33%), Positives = 109/212 (51%), Gaps = 4/212 (1%)
Query: 169 VKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
V+ LI DVN ++ R+PLH A E+++ L+ +GA + TPLH A +
Sbjct: 57 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 116
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
S ++LL ADV A T LH+AA + +CA L+ ++++ + G+T
Sbjct: 117 SCSEEAVQVLLKHSADVNAR-DKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRT 175
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LH A + E+V++L+ R A++ A D R +H A G ++ +LL+S GA+
Sbjct: 176 ALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMG--HIEVVKLLVSHGAEVT 233
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
D YTPLH AA + + V LLD G D+
Sbjct: 234 CKDKKSYTPLHAAASSGMISVVKYLLDLGVDM 265
Score = 90.6 bits (215), Expect = 2e-17
Identities = 78/260 (30%), Positives = 118/260 (45%), Gaps = 13/260 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL-----LDHGAHPNTWD--SSTETKAT 155
LL+ +P D G +H S G C++L+ LD + D S ++ +AT
Sbjct: 524 LLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRAT 583
Query: 156 --PLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
PLH AA ++VL+ D++ S R+PL A E V L+ GA
Sbjct: 584 ISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 643
Query: 213 TPQ-VFTETPLHVAASLGSASCTKLLL-NAGADVRAAMGPGKA-TALHLAAEDGHAECAR 269
+ TP+H AA+ G + C +LL+ NA + G T L L+ +GH +C
Sbjct: 644 VKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVY 703
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA++D + G+T LH + E V+ L+ A +D+ GRTP+H + G
Sbjct: 704 SLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACG 763
Query: 330 ARACDIARLLLSAGADPNAA 349
A L +A D N A
Sbjct: 764 HIGVLGALLQSAASMDANPA 783
Score = 67.7 bits (158), Expect = 1e-10
Identities = 42/129 (32%), Positives = 65/129 (50%), Gaps = 2/129 (1%)
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+G + R L+ +++ + +TPLH A E++E+L+ A V AKD+ TP
Sbjct: 51 NGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTP 110
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
LH A+ + + ++LL AD NA D TPLHIAA N+ C L+ +V +
Sbjct: 111 LHRAVASCSE--EAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 168
Query: 382 RTNGGVSAL 390
G +AL
Sbjct: 169 SDRAGRTAL 177
Score = 58.8 bits (136), Expect = 7e-08
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 8/127 (6%)
Query: 55 YSEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELD 114
+SE + +LIGN Q A + + G G +T ++ + G + ++ LL G + D D
Sbjct: 662 HSECLRLLIGNAEP----QNAVDIQDGNG-QTPLMLSVLNGHTDCVYSLLNKGANVDAKD 716
Query: 115 DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIA 174
GRT LH + G EECV LL HGA DS TP+H +A+ + + L+
Sbjct: 717 KWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGR---TPIHLSAACGHIGVLGALLQ 773
Query: 175 HGADVNA 181
A ++A
Sbjct: 774 SAASMDA 780
>AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens
cDNA FLJ44940 fis, clone BRAMY4000915, weakly similar
to Ankyrin 1. ).
Length = 687
Score = 157 bits (380), Expect = 2e-37
Identities = 109/310 (35%), Positives = 151/310 (48%), Gaps = 8/310 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A + G ++ LL G + + D R +H + +G E VKLL+ HGA
Sbjct: 174 RTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 233
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + TPLH AAS+ ++ VK L+ G D+N +PLH A + VV E
Sbjct: 234 CKDKKS---YTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNE 290
Query: 204 LLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L++ GA + TPLH AAS A C +LL+ GADV GK T LH+ A
Sbjct: 291 LIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGK-TPLHMTALH 349
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G ++ ++ GA ID + G TPLH+A ++ L+ AD + G PL
Sbjct: 350 GRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPL 409
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A + G C R LLS+G D + D+FG T LH AA C+ LLL+ G D +
Sbjct: 410 HLAALSGFSDC--CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 467
Query: 383 TNGGVSALSF 392
G S L +
Sbjct: 468 DKFGRSPLHY 477
Score = 156 bits (379), Expect = 2e-37
Identities = 106/293 (36%), Positives = 148/293 (50%), Gaps = 9/293 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH-CAA 161
LL +GVD +E + G T LH++C G + V L+D GA N E TPLH AA
Sbjct: 258 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVN---QKNEKGFTPLHFAAA 314
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
S C+++L+ +GADVN D ++PLH L + ++++GA D T
Sbjct: 315 STHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNT 374
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G L+ +GAD A G LHLAA G ++C R LL G ID
Sbjct: 375 PLHIAARYGHELLINTLITSGADT-AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 433
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P+ G+T LH A +LE + +L++ AD KD GR+PLH A C A L+
Sbjct: 434 PDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA--LV 491
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA-CVLLLLDYGGDVTLRTNGGVSALSF 392
+GA N D G TPLH AA ++ C+ LL + +R G +A+ +
Sbjct: 492 GSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHY 544
Score = 145 bits (352), Expect = 4e-34
Identities = 100/279 (35%), Positives = 139/279 (49%), Gaps = 8/279 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D AGRT LH + G E VKLLL GA+ N +D + +A +H AA + VK+L+
Sbjct: 170 DRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKK-DRRA--IHWAAYMGHIEVVKLLV 226
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
+HGA+V +PLH A S VVK LL+ G + P + TPLHVA G
Sbjct: 227 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDV 286
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGH-AECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ GA V G T LH AA H A C LL+ +GA ++ + G+TPLH+
Sbjct: 287 VVNELIDCGAIVNQKNEKG-FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHM 345
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
L + ++ A + +D +G TPLH A G + L+++GAD
Sbjct: 346 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHEL--LINTLITSGADTAKRGI 403
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G PLH+AAL+ FS C LL G D+ + G + L
Sbjct: 404 HGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCL 442
Score = 137 bits (331), Expect = 2e-31
Identities = 103/312 (33%), Positives = 148/312 (47%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D T LH + SEE V++LL H A N
Sbjct: 75 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 134
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C + L+ ++VN + + R+ LH+A S E+VK
Sbjct: 135 ARDKNWQ---TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 191
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + +H AA +G KLL++ GA+V T LH AA G
Sbjct: 192 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV-TCKDKKSYTPLHAAASSG 250
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LLD G ++ PN G TPLH+A VV L+D A V K+ G TPLH
Sbjct: 251 MISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 310
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL+ GAD N G TPLH+ AL+ + ++ G +
Sbjct: 311 FAAASTHGALCL-ELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCED 369
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 370 KNGNTPLHIAAR 381
Score = 135 bits (327), Expect = 5e-31
Identities = 88/241 (36%), Positives = 125/241 (51%), Gaps = 4/241 (1%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACP 211
K TPLH AA +++LI GA VNA S +PLH AV S + E V+ LL+ A
Sbjct: 74 KRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADV 133
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ +TPLH+AA+ + C + L+ ++V + G+ TALH AA GH E +LL
Sbjct: 134 NARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR-TALHHAAFSGHGEMVKLL 192
Query: 272 LDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGAR 331
L GA+I+ + + + +H A +EVV++LV A+V KD TPLH A G
Sbjct: 193 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM- 251
Query: 332 ACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
+ + LL G D N + +G TPLH+A N V L+D G V + G + L
Sbjct: 252 -ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 310
Query: 392 F 392
F
Sbjct: 311 F 311
Score = 120 bits (288), Expect = 2e-26
Identities = 90/264 (34%), Positives = 130/264 (49%), Gaps = 21/264 (7%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
KLL G D D DD GRTCLH + G+ EC+ LLL+ GA N D + +PLH AA
Sbjct: 423 KLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD---KFGRSPLHYAA 479
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAP-EVVKELLEAGACPDTPQVFT 218
+ + C+ L+ GA VN L +R +PLHYA SD + ++ LL A P
Sbjct: 480 ANCNYQCLFALVGSGASVN-DLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQG 538
Query: 219 ETPLHVAASLGSASCTKLLLN----------AGADVRA-AMGPGKATALHLAAEDGHAEC 267
+H +A+ G C +L+ + +G D+ + + + LHLAA GH +
Sbjct: 539 YNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQA 598
Query: 268 ARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD-ADGRTPLHGAI 326
+L+ +D N G+TPL LA +E V++L+++ A + KD RTP+H A
Sbjct: 599 LEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAA 658
Query: 327 VRGARACDIARLLLSAGADPNAAD 350
G C RLL+ NA D
Sbjct: 659 TNGHSEC--LRLLIGNAEPQNAVD 680
Score = 114 bits (275), Expect = 9e-25
Identities = 100/358 (27%), Positives = 157/358 (43%), Gaps = 11/358 (3%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCL-VGSEECVKLLLDHGAHPNTWDSS 149
AC+ G+ +++ +L+ G ++ ++ G T LH + C++LL+ +GA N S
Sbjct: 279 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNM--KS 336
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAG 208
+ K TPLH A + + +I GA ++ + +PLH A ++ L+ +G
Sbjct: 337 KDGK-TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSG 395
Query: 209 ACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECA 268
A + PLH+AA G + C + LL++G D+ G+ T LH AA G+ EC
Sbjct: 396 ADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGR-TCLHAAAAGGNLECL 454
Query: 269 RLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVR 328
LLL+ GA + + G++PLH A + + + LV A V D G TPLH A
Sbjct: 455 NLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATS 514
Query: 329 GARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVS 388
LL A+P D GY +H +A C+ L+ L G
Sbjct: 515 DTDG-KCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 573
Query: 389 ALSFIVRRVPDVIPRYLCKF---DDAVHVSEHELGDVDCELTIDFRPLVPCLTRGEAE 443
LS R + P +L + A+ V L D+D + PL +G E
Sbjct: 574 MLSDSDNRA-TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 630
Score = 103 bits (246), Expect = 3e-21
Identities = 95/296 (32%), Positives = 139/296 (46%), Gaps = 25/296 (8%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G +L+ L+ G D + G LHL+ L G +C + LL G +T D +
Sbjct: 383 GHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPD---DFGR 439
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
T LH AA+ +L C+ +L+ GAD N RSPLHYA + + + L+ +GA +
Sbjct: 440 TCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVND 499
Query: 214 PQVFTETPLHVAASLGS-ASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARL 270
TPLH AA+ + C + LL +A VR G A+H +A GH C +L
Sbjct: 500 LDERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQG---YNAVHYSAAYGHRLCLQL 556
Query: 271 L-----LD-----HGAHI--DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
+ LD G + D N +PLHLA + +E+LV D+ +++ G
Sbjct: 557 IASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSG 616
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNF-GYTPLHIAALNEFSACVLLLL 373
RTPL A +G C +L++ GA D TP+H AA N S C+ LL+
Sbjct: 617 RTPLDLAAFKGHVEC--VDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLI 670
Score = 99 bits (238), Expect = 3e-20
Identities = 70/212 (33%), Positives = 109/212 (51%), Gaps = 4/212 (1%)
Query: 169 VKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
V+ LI DVN ++ R+PLH A E+++ L+ +GA + TPLH A +
Sbjct: 57 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 116
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
S ++LL ADV A T LH+AA + +CA L+ ++++ + G+T
Sbjct: 117 SCSEEAVQVLLKHSADVNAR-DKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRT 175
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LH A + E+V++L+ R A++ A D R +H A G ++ +LL+S GA+
Sbjct: 176 ALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMG--HIEVVKLLVSHGAEVT 233
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
D YTPLH AA + + V LLD G D+
Sbjct: 234 CKDKKSYTPLHAAASSGMISVVKYLLDLGVDM 265
Score = 67.7 bits (158), Expect = 1e-10
Identities = 42/129 (32%), Positives = 65/129 (50%), Gaps = 2/129 (1%)
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+G + R L+ +++ + +TPLH A E++E+L+ A V AKD+ TP
Sbjct: 51 NGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTP 110
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
LH A+ + + ++LL AD NA D TPLHIAA N+ C L+ +V +
Sbjct: 111 LHRAVASCSE--EAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 168
Query: 382 RTNGGVSAL 390
G +AL
Sbjct: 169 SDRAGRTAL 177
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A + G L L++ +D D + +GRT L L+ G ECV +L++ GA D
Sbjct: 590 AAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYI- 648
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA 181
K TP+H AA+ C+++LI + NA
Sbjct: 649 -LKRTPIHAAATNGHSECLRLLIGNAEPQNA 678
>AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein.
Length = 1059
Score = 157 bits (380), Expect = 2e-37
Identities = 109/310 (35%), Positives = 151/310 (48%), Gaps = 8/310 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A + G ++ LL G + + D R +H + +G E VKLL+ HGA
Sbjct: 147 RTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVT 206
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + TPLH AAS+ ++ VK L+ G D+N +PLH A + VV E
Sbjct: 207 CKDKKS---YTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNE 263
Query: 204 LLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L++ GA + TPLH AAS A C +LL+ GADV GK T LH+ A
Sbjct: 264 LIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGK-TPLHMTALH 322
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G ++ ++ GA ID + G TPLH+A ++ L+ AD + G PL
Sbjct: 323 GRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPL 382
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A + G C R LLS+G D + D+FG T LH AA C+ LLL+ G D +
Sbjct: 383 HLAALSGFSDC--CRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 440
Query: 383 TNGGVSALSF 392
G S L +
Sbjct: 441 DKFGRSPLHY 450
Score = 157 bits (380), Expect = 2e-37
Identities = 106/293 (36%), Positives = 148/293 (50%), Gaps = 9/293 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH-CAA 161
LL +GVD +E + G T LH++C G + V L+D GA N E TPLH AA
Sbjct: 231 LLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVN---QKNEKGFTPLHFAAA 287
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
S C+++L+ +GADVN D ++PLH L + ++++GA D T
Sbjct: 288 STHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNT 347
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G L+ +GAD A G LHLAA G ++C R LL G ID
Sbjct: 348 PLHIAARYGHELLINTLITSGADT-AKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDT 406
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P+ G+T LH A +LE + +L++ AD KD GR+PLH A C A L+
Sbjct: 407 PDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFA--LV 464
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA-CVLLLLDYGGDVTLRTNGGVSALSF 392
+GA N D G TPLH AA ++ C+ LL + +R G +A+ +
Sbjct: 465 GSGASVNDLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHY 517
Score = 145 bits (352), Expect = 4e-34
Identities = 100/279 (35%), Positives = 139/279 (49%), Gaps = 8/279 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D AGRT LH + G E VKLLL GA+ N +D + +A +H AA + VK+L+
Sbjct: 143 DRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKK-DRRA--IHWAAYMGHIEVVKLLV 199
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
+HGA+V +PLH A S VVK LL+ G + P + TPLHVA G
Sbjct: 200 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDV 259
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGH-AECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ GA V G T LH AA H A C LL+ +GA ++ + G+TPLH+
Sbjct: 260 VVNELIDCGAIVNQKNEKG-FTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHM 318
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
L + ++ A + +D +G TPLH A G + L+++GAD
Sbjct: 319 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHEL--LINTLITSGADTAKRGI 376
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G PLH+AAL+ FS C LL G D+ + G + L
Sbjct: 377 HGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCL 415
Score = 138 bits (334), Expect = 7e-32
Identities = 105/307 (34%), Positives = 152/307 (49%), Gaps = 24/307 (7%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
KLL G D D DD GRTCLH + G+ EC+ LLL+ GA N D + +PLH AA
Sbjct: 396 KLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKD---KFGRSPLHYAA 452
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAP-EVVKELLEAGACPDTPQVFT 218
+ + C+ L+ GA VN L +R +PLHYA SD + ++ LL A P
Sbjct: 453 ANCNYQCLFALVGSGASVN-DLDERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQG 511
Query: 219 ETPLHVAASLGSASCTKLLLN----------AGADVRA-AMGPGKATALHLAAEDGHAEC 267
+H +A+ G C +L+ + +G D+ + + + LHLAA GH +
Sbjct: 512 YNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQA 571
Query: 268 ARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD-ADGRTPLHGAI 326
+L+ +D N G+TPL LA +E V++L+++ A + KD RTP+H A
Sbjct: 572 LEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAA 631
Query: 327 VRGARACDIARLLLSAGADPNAA---DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G C RLL+ NA D G TPL ++ LN + CV LL+ G +V +
Sbjct: 632 TNGHSEC--LRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGANVDAKD 689
Query: 384 NGGVSAL 390
G +AL
Sbjct: 690 KWGRTAL 696
Score = 137 bits (331), Expect = 2e-31
Identities = 103/312 (33%), Positives = 148/312 (47%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D T LH + SEE V++LL H A N
Sbjct: 48 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 107
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C + L+ ++VN + + R+ LH+A S E+VK
Sbjct: 108 ARDKNWQ---TPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKL 164
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + +H AA +G KLL++ GA+V T LH AA G
Sbjct: 165 LLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEV-TCKDKKSYTPLHAAASSG 223
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LLD G ++ PN G TPLH+A VV L+D A V K+ G TPLH
Sbjct: 224 MISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 283
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL+ GAD N G TPLH+ AL+ + ++ G +
Sbjct: 284 FAAASTHGALCL-ELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQTIIQSGAVIDCED 342
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 343 KNGNTPLHIAAR 354
Score = 135 bits (327), Expect = 5e-31
Identities = 88/241 (36%), Positives = 125/241 (51%), Gaps = 4/241 (1%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACP 211
K TPLH AA +++LI GA VNA S +PLH AV S + E V+ LL+ A
Sbjct: 47 KRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADV 106
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ +TPLH+AA+ + C + L+ ++V + G+ TALH AA GH E +LL
Sbjct: 107 NARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGR-TALHHAAFSGHGEMVKLL 165
Query: 272 LDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGAR 331
L GA+I+ + + + +H A +EVV++LV A+V KD TPLH A G
Sbjct: 166 LSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGM- 224
Query: 332 ACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
+ + LL G D N + +G TPLH+A N V L+D G V + G + L
Sbjct: 225 -ISVVKYLLDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLH 283
Query: 392 F 392
F
Sbjct: 284 F 284
Score = 124 bits (300), Expect = 9e-28
Identities = 111/348 (31%), Positives = 160/348 (45%), Gaps = 22/348 (6%)
Query: 55 YSEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELD 114
+SE + +LIGN Q A + + G G +T ++ + G + ++ LL G + D D
Sbjct: 635 HSECLRLLIGNAEP----QNAVDIQDGNG-QTPLMLSVLNGHTDCVYSLLNKGANVDAKD 689
Query: 115 DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIA 174
GRT LH + G EECV LL HGA DS TP+H +A+ + + L+
Sbjct: 690 KWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGR---TPIHLSAACGHIGVLGALLQ 746
Query: 175 HGA--DVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLG 229
A D N +D + LH+A + V+ LLE T + +PLH A
Sbjct: 747 SAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKT-EGNAFSPLHCAVIND 805
Query: 230 SASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTP 288
+ ++L++ GA + A T LH AA H EC +LLL H A ++ + G+TP
Sbjct: 806 NEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTP 865
Query: 289 LHLATLAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADP- 346
L +A VEMLV A++ +D T LH A +G A L+L D
Sbjct: 866 LMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETS--ALLILEKITDRN 923
Query: 347 --NAADNFGYTPLHIAALNEFSACVLLLLDYGGDV-TLRTNGGVSALS 391
NA + TPLH+AA N + V LL G V + NG AL+
Sbjct: 924 LINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALA 971
Score = 114 bits (274), Expect = 1e-24
Identities = 100/358 (27%), Positives = 157/358 (43%), Gaps = 11/358 (3%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCL-VGSEECVKLLLDHGAHPNTWDSS 149
AC+ G+ +++ +L+ G ++ ++ G T LH + C++LL+ +GA N S
Sbjct: 252 ACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNM--KS 309
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAG 208
+ K TPLH A + + +I GA ++ + +PLH A ++ L+ +G
Sbjct: 310 KDGK-TPLHMTALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSG 368
Query: 209 ACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECA 268
A + PLH+AA G + C + LL++G D+ G+ T LH AA G+ EC
Sbjct: 369 ADTAKRGIHGMFPLHLAALSGFSDCCRKLLSSGFDIDTPDDFGR-TCLHAAAAGGNLECL 427
Query: 269 RLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVR 328
LLL+ GA + + G++PLH A + + + LV A V D G TPLH A
Sbjct: 428 NLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAATS 487
Query: 329 GARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVS 388
LL A+P D GY +H +A C+ L+ L G
Sbjct: 488 DTDG-KCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 546
Query: 389 ALSFIVRRVPDVIPRYLCKF---DDAVHVSEHELGDVDCELTIDFRPLVPCLTRGEAE 443
LS R + P +L + A+ V L D+D + PL +G E
Sbjct: 547 MLSDSDNRA-TISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 603
Score = 114 bits (274), Expect = 1e-24
Identities = 96/299 (32%), Positives = 140/299 (46%), Gaps = 19/299 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL-----LDHGAHPNTWD--SSTETKAT 155
LL+ +P D G +H S G C++L+ LD + D S ++ +AT
Sbjct: 497 LLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRAT 556
Query: 156 --PLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
PLH AA ++VL+ D++ S R+PL A E V L+ GA
Sbjct: 557 ISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 616
Query: 213 TPQ-VFTETPLHVAASLGSASCTKLLL-NAGADVRAAMGPGKA-TALHLAAEDGHAECAR 269
+ TP+H AA+ G + C +LL+ NA + G T L L+ +GH +C
Sbjct: 617 VKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVY 676
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA++D + G+T LH + E V+ L+ A +D+ GRTP+H + G
Sbjct: 677 SLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACG 736
Query: 330 ARACDIARLLLSAG---ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
+ LL SA A+P ADN GYT LH A N CV LLL+ +V +T G
Sbjct: 737 HIGV-LGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQ--EVFQKTEG 792
Score = 110 bits (265), Expect = 2e-23
Identities = 99/333 (29%), Positives = 158/333 (47%), Gaps = 29/333 (8%)
Query: 74 FASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECV 133
F + FG RT + A G L LL G D ++ D GR+ LH + + +C+
Sbjct: 402 FDIDTPDDFG-RTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCL 460
Query: 134 KLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA-CVKVLIAHGADVNAGLSDR---SPL 189
L+ GA N D E TPLH AA++ + C++ L+ + D N G+ D+ + +
Sbjct: 461 FALVGSGASVNDLD---ERGCTPLHYAATSDTDGKCLEYLLRN--DANPGIRDKQGYNAV 515
Query: 190 HYA-----------VLSDAP-EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
HY+ + S+ P +V+ E D+ T +PLH+AA G ++L
Sbjct: 516 HYSAAYGHRLCLQLIASETPLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVL 575
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF-RGQTPLHLATLAQ 296
+ + D+ G+ T L LAA GH EC +L++ GA I ++ +TP+H A
Sbjct: 576 VQSLLDLDVRNSSGR-TPLDLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNG 634
Query: 297 SLEVVEMLVDRCADVRA---KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFG 353
E + +L+ A +D +G+TPL +++ G C + LL+ GA+ +A D +G
Sbjct: 635 HSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYS--LLNKGANVDAKDKWG 692
Query: 354 YTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
T LH A+ CV LL +G LR + G
Sbjct: 693 RTALHRGAVTGHEECVDALLQHGAKCLLRDSRG 725
Score = 107 bits (258), Expect = 1e-22
Identities = 94/309 (30%), Positives = 140/309 (45%), Gaps = 14/309 (4%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A + G L L++ +D D + +GRT L L+ G ECV +L++ GA D
Sbjct: 563 AAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYI- 621
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSD---RSPLHYAVLSDAPEVVKELLE 206
K TP+H AA+ C+++LI + NA + D ++PL +VL+ + V LL
Sbjct: 622 -LKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLN 680
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE 266
GA D + T LH A G C LL GA G+ T +HL+A GH
Sbjct: 681 KGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGR-TPIHLSAACGHIG 739
Query: 267 CARLLLDHGAHID----WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
LL A +D + G T LH A VE+L+++ + + + +PL
Sbjct: 740 VLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQ-EVFQKTEGNAFSPL 798
Query: 323 HGAIVRGARACDIARLLLSAGAD-PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
H A++ L+ + GA NA D+ G TPLH AA + C+ LLL + V
Sbjct: 799 HCAVINDNEGA-AEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNS 857
Query: 382 RTNGGVSAL 390
+ G + L
Sbjct: 858 VDSTGKTPL 866
Score = 99 bits (238), Expect = 3e-20
Identities = 70/212 (33%), Positives = 109/212 (51%), Gaps = 4/212 (1%)
Query: 169 VKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
V+ LI DVN ++ R+PLH A E+++ L+ +GA + TPLH A +
Sbjct: 30 VRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVA 89
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
S ++LL ADV A T LH+AA + +CA L+ ++++ + G+T
Sbjct: 90 SCSEEAVQVLLKHSADVNAR-DKNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRT 148
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LH A + E+V++L+ R A++ A D R +H A G ++ +LL+S GA+
Sbjct: 149 ALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMG--HIEVVKLLVSHGAEVT 206
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
D YTPLH AA + + V LLD G D+
Sbjct: 207 CKDKKSYTPLHAAASSGMISVVKYLLDLGVDM 238
Score = 67.7 bits (158), Expect = 1e-10
Identities = 42/129 (32%), Positives = 65/129 (50%), Gaps = 2/129 (1%)
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+G + R L+ +++ + +TPLH A E++E+L+ A V AKD+ TP
Sbjct: 24 NGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTP 83
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
LH A+ + + ++LL AD NA D TPLHIAA N+ C L+ +V +
Sbjct: 84 LHRAVASCSE--EAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVNV 141
Query: 382 RTNGGVSAL 390
G +AL
Sbjct: 142 SDRAGRTAL 150
Score = 62.9 bits (146), Expect = 4e-09
Identities = 55/166 (33%), Positives = 74/166 (44%), Gaps = 12/166 (7%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + EC++LLL H A N+ DS T TPL AA V++L+
Sbjct: 826 DSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDS---TGKTPLMMAAENGQTNTVEMLV 882
Query: 174 AHGADVNAGLSDRSP---LHYAVL----SDAPEVVKELLEAGACPDTPQVFTETPLHVAA 226
+ A L D S LH A + A +++++ + T +TPLHVAA
Sbjct: 883 S-SASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAAL-QTPLHVAA 940
Query: 227 SLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
G + LL GA V A G AL A A+C L+L
Sbjct: 941 RNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALIL 986
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAG 343
R Q L A + V L+ + DV +D + RTPLH A G +I LL+ +G
Sbjct: 13 RDQPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLG--DAEIIELLILSG 70
Query: 344 ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
A NA D+ TPLH A + V +LL + DV R
Sbjct: 71 ARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNAR 109
>BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein.
Length = 579
Score = 155 bits (376), Expect = 5e-37
Identities = 98/264 (37%), Positives = 137/264 (51%), Gaps = 8/264 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH-CAA 161
LL +GV+ DE++ G T LH++C G + V L+D+GA+ N TPLH AA
Sbjct: 225 LLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVN---QPNNNGFTPLHFAAA 281
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
S C+++L+ +GADVN D +SPLH + + L++ G D T
Sbjct: 282 STHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNT 341
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLHVAA G L+ +GAD A G LHLAA + H++C R LL G ID
Sbjct: 342 PLHVAARYGHELLINTLITSGADT-AKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDT 400
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P+ G+T LH A ++E +++L AD KD GRTPLH A C L+
Sbjct: 401 PDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHC--IETLV 458
Query: 341 SAGADPNAADNFGYTPLHIAALNE 364
+ GA+ N D++G T LH AA ++
Sbjct: 459 TTGANVNETDDWGRTALHYAAASD 482
Score = 140 bits (340), Expect = 1e-32
Identities = 95/266 (35%), Positives = 141/266 (53%), Gaps = 7/266 (2%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-R 186
G E +++L+ NT DS K TPLH AA +++LI GA VNA +
Sbjct: 19 GDPEEIRMLIHKTEDVNTLDSE---KRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWL 75
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH AV S + E V+ L++ A + +TPLHVAA+ + C ++++ + V
Sbjct: 76 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV 135
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
+ G+ TALH AA +GH E LLL GA+I+ + + + LH A L+VV +L++
Sbjct: 136 SDRGGR-TALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLIN 194
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
A+V KD G TPLH A G ++ + LL+ G + + + +G T LHIA N
Sbjct: 195 HGAEVTCKDKKGYTPLHAAASNGQ--INVVKHLLNLGVEIDEINVYGNTALHIACYNGQD 252
Query: 367 ACVLLLLDYGGDVTLRTNGGVSALSF 392
A V L+DYG +V N G + L F
Sbjct: 253 AVVNELIDYGANVNQPNNNGFTPLHF 278
Score = 133 bits (322), Expect = 2e-30
Identities = 102/312 (32%), Positives = 150/312 (48%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D+ T LH + SEE V++L+ H A N
Sbjct: 42 RTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 101
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C +V+I + VN + R+ LH+A L+ E+V
Sbjct: 102 ARDKNWQ---TPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNL 158
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + LH AA +G LL+N GA+V G T LH AA +G
Sbjct: 159 LLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG-YTPLHAAASNG 217
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LL+ G ID N G T LH+A VV L+D A+V + +G TPLH
Sbjct: 218 QINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLH 277
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL++ GAD N G +PLH+ A++ L+ GG++
Sbjct: 278 FAAASTHGALCL-ELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVD 336
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 337 KDGNTPLHVAAR 348
Score = 133 bits (322), Expect = 2e-30
Identities = 102/312 (32%), Positives = 145/312 (46%), Gaps = 8/312 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G RTA+ A G ++ LL G + + D R LH + +G + V LL++HGA
Sbjct: 139 GGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 198
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVV 201
D + TPLH AAS + VK L+ G +++ + + LH A + VV
Sbjct: 199 VTCKD---KKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 255
Query: 202 KELLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAA 260
EL++ GA + P TPLH AAS A C +LL+N GADV GK + LH+ A
Sbjct: 256 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGK-SPLHMTA 314
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
G ++ L+ +G ID + G TPLH+A ++ L+ AD
Sbjct: 315 VHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMF 374
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
PLH A + C R LLS+G + + D FG T LH AA C+ LL G D
Sbjct: 375 PLHLAALNAHSDC--CRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFH 432
Query: 381 LRTNGGVSALSF 392
+ G + L +
Sbjct: 433 KKDKCGRTPLHY 444
Score = 131 bits (316), Expect = 1e-29
Identities = 94/268 (35%), Positives = 130/268 (48%), Gaps = 8/268 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + L G E V LLL GA+ N +D + +A LH AA L V +LI
Sbjct: 137 DRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKK-DRRA--LHWAAYMGHLDVVALLI 193
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
HGA+V +PLH A + VVK LL G D V+ T LH+A G +
Sbjct: 194 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDA 253
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGH-AECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ GA+V G T LH AA H A C LL+++GA ++ + G++PLH+
Sbjct: 254 VVNELIDYGANVNQPNNNG-FTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 312
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
+ + L+ ++ D DG TPLH A G + L+++GAD
Sbjct: 313 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHEL--LINTLITSGADTAKCGI 370
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDV 379
PLH+AALN S C LL G ++
Sbjct: 371 HSMFPLHLAALNAHSDCCRKLLSSGFEI 398
Score = 116 bits (279), Expect = 3e-25
Identities = 97/310 (31%), Positives = 138/310 (44%), Gaps = 8/310 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R A+ WA ++G ++ L+ G + D G T LH + G VK LL+ G
Sbjct: 174 RRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEI- 232
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKE 203
D T LH A A V LI +GA+VN ++ +PLH+A S + E
Sbjct: 233 --DEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLE 290
Query: 204 LL-EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + ++PLH+ A G + ++ L+ G ++ G T LH+AA
Sbjct: 291 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGN-TPLHVAARY 349
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH L+ GA PLHLA L + L+ ++ D GRT L
Sbjct: 350 GHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCL 409
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A G C +LL S+GAD + D G TPLH AA N C+ L+ G +V
Sbjct: 410 HAAAAGGNVEC--IKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNET 467
Query: 383 TNGGVSALSF 392
+ G +AL +
Sbjct: 468 DDWGRTALHY 477
Score = 108 bits (259), Expect = 8e-23
Identities = 70/208 (33%), Positives = 106/208 (50%), Gaps = 3/208 (1%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
L+D+ PL A+ S PE ++ L+ +T TPLHVAA LG A +LL+ +GA
Sbjct: 6 LTDQPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGA 65
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
V A T LH A E ++L+ H A ++ + QTPLH+A ++++ E
Sbjct: 66 RVNAKDNMW-LTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAE 124
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
+++ + V D GRT LH A + G ++ LLL+ GA+ NA D LH AA
Sbjct: 125 VIIPLLSSVNVSDRGGRTALHHAALNG--HVEMVNLLLAKGANINAFDKKDRRALHWAAY 182
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSAL 390
V LL+++G +VT + G + L
Sbjct: 183 MGHLDVVALLINHGAEVTCKDKKGYTPL 210
Score = 103 bits (247), Expect = 2e-21
Identities = 82/278 (29%), Positives = 124/278 (44%), Gaps = 14/278 (5%)
Query: 97 SILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATP 156
++ L L+ G D + G++ LH++ + G + L+ +G + D T P
Sbjct: 286 ALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNT---P 342
Query: 157 LHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
LH AA + LI GAD G+ PLH A L+ + ++LL +G DTP
Sbjct: 343 LHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPD 402
Query: 216 VFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
F T LH AA+ G+ C KLL ++GAD G+ T LH AA + H C L+ G
Sbjct: 403 KFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGR-TPLHYAAANCHFHCIETLVTTG 461
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAI-VRGARACD 334
A+++ + G+T LH A + +DR + D L A ++ A
Sbjct: 462 ANVNETDDWGRTALHYAAASD--------MDRNKTILGNAHDNSEELERARELKEKEATL 513
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
LL A+P+ D GY +H AA C+ L+
Sbjct: 514 CLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELV 551
Score = 71.7 bits (168), Expect = 9e-12
Identities = 62/192 (32%), Positives = 84/192 (43%), Gaps = 18/192 (9%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
KLL G + D D GRTCLH + G+ EC+KLL GA + + TPLH AA
Sbjct: 390 KLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGA---DFHKKDKCGRTPLHYAA 446
Query: 162 SAKSLACVKVLIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
+ C++ L+ GA+VN R+ LHYA SD + K +L G D +
Sbjct: 447 ANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDM-DRNKTIL--GNAHDNSEELERA 503
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL-------LD 273
+ C + LL A+ G ++H AA GH +C L+ L
Sbjct: 504 --RELKEKEATLCLEFLLQNDANPSIRDKEG-YNSIHYAAAYGHRQCLELVSCFVLFSLT 560
Query: 274 HGAHIDWPNFRG 285
H H PN RG
Sbjct: 561 H-THTHTPNHRG 571
>AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein.
Length = 525
Score = 155 bits (376), Expect = 5e-37
Identities = 98/264 (37%), Positives = 137/264 (51%), Gaps = 8/264 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH-CAA 161
LL +GV+ DE++ G T LH++C G + V L+D+GA+ N TPLH AA
Sbjct: 200 LLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVN---QPNNNGFTPLHFAAA 256
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
S C+++L+ +GADVN D +SPLH + + L++ G D T
Sbjct: 257 STHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNT 316
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLHVAA G L+ +GAD A G LHLAA + H++C R LL G ID
Sbjct: 317 PLHVAARYGHELLINTLITSGADT-AKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDT 375
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P+ G+T LH A ++E +++L AD KD GRTPLH A C L+
Sbjct: 376 PDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHC--IETLV 433
Query: 341 SAGADPNAADNFGYTPLHIAALNE 364
+ GA+ N D++G T LH AA ++
Sbjct: 434 TTGANVNETDDWGRTALHYAAASD 457
Score = 136 bits (329), Expect = 3e-31
Identities = 92/250 (36%), Positives = 134/250 (53%), Gaps = 7/250 (2%)
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVK 202
NT DS K TPLH AA +++LI GA VNA + +PLH AV S + E V+
Sbjct: 10 NTLDSE---KRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQ 66
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L++ A + +TPLHVAA+ + C ++++ + V + G+ TALH AA +
Sbjct: 67 VLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGR-TALHHAALN 125
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E LLL GA+I+ + + + LH A L+VV +L++ A+V KD G TPL
Sbjct: 126 GHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPL 185
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A G ++ + LL+ G + + + +G T LHIA N A V L+DYG +V
Sbjct: 186 HAAASNGQ--INVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQP 243
Query: 383 TNGGVSALSF 392
N G + L F
Sbjct: 244 NNNGFTPLHF 253
Score = 133 bits (322), Expect = 2e-30
Identities = 102/312 (32%), Positives = 150/312 (48%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D+ T LH + SEE V++L+ H A N
Sbjct: 17 RTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 76
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C +V+I + VN + R+ LH+A L+ E+V
Sbjct: 77 ARDKNWQ---TPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNL 133
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + LH AA +G LL+N GA+V G T LH AA +G
Sbjct: 134 LLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG-YTPLHAAASNG 192
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LL+ G ID N G T LH+A VV L+D A+V + +G TPLH
Sbjct: 193 QINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLH 252
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL++ GAD N G +PLH+ A++ L+ GG++
Sbjct: 253 FAAASTHGALCL-ELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVD 311
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 312 KDGNTPLHVAAR 323
Score = 133 bits (322), Expect = 2e-30
Identities = 102/312 (32%), Positives = 145/312 (46%), Gaps = 8/312 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G RTA+ A G ++ LL G + + D R LH + +G + V LL++HGA
Sbjct: 114 GGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 173
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVV 201
D + TPLH AAS + VK L+ G +++ + + LH A + VV
Sbjct: 174 VTCKD---KKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 230
Query: 202 KELLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAA 260
EL++ GA + P TPLH AAS A C +LL+N GADV GK + LH+ A
Sbjct: 231 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGK-SPLHMTA 289
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
G ++ L+ +G ID + G TPLH+A ++ L+ AD
Sbjct: 290 VHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMF 349
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
PLH A + C R LLS+G + + D FG T LH AA C+ LL G D
Sbjct: 350 PLHLAALNAHSDC--CRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFH 407
Query: 381 LRTNGGVSALSF 392
+ G + L +
Sbjct: 408 KKDKCGRTPLHY 419
Score = 131 bits (316), Expect = 1e-29
Identities = 94/268 (35%), Positives = 130/268 (48%), Gaps = 8/268 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + L G E V LLL GA+ N +D + +A LH AA L V +LI
Sbjct: 112 DRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKK-DRRA--LHWAAYMGHLDVVALLI 168
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
HGA+V +PLH A + VVK LL G D V+ T LH+A G +
Sbjct: 169 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDA 228
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGH-AECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ GA+V G T LH AA H A C LL+++GA ++ + G++PLH+
Sbjct: 229 VVNELIDYGANVNQPNNNG-FTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
+ + L+ ++ D DG TPLH A G + L+++GAD
Sbjct: 288 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHEL--LINTLITSGADTAKCGI 345
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDV 379
PLH+AALN S C LL G ++
Sbjct: 346 HSMFPLHLAALNAHSDCCRKLLSSGFEI 373
Score = 116 bits (279), Expect = 3e-25
Identities = 97/310 (31%), Positives = 138/310 (44%), Gaps = 8/310 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R A+ WA ++G ++ L+ G + D G T LH + G VK LL+ G
Sbjct: 149 RRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEI- 207
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKE 203
D T LH A A V LI +GA+VN ++ +PLH+A S + E
Sbjct: 208 --DEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLE 265
Query: 204 LL-EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + ++PLH+ A G + ++ L+ G ++ G T LH+AA
Sbjct: 266 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGN-TPLHVAARY 324
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH L+ GA PLHLA L + L+ ++ D GRT L
Sbjct: 325 GHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCL 384
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A G C +LL S+GAD + D G TPLH AA N C+ L+ G +V
Sbjct: 385 HAAAAGGNVEC--IKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNET 442
Query: 383 TNGGVSALSF 392
+ G +AL +
Sbjct: 443 DDWGRTALHY 452
Score = 103 bits (246), Expect = 3e-21
Identities = 82/277 (29%), Positives = 123/277 (44%), Gaps = 14/277 (5%)
Query: 97 SILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATP 156
++ L L+ G D + G++ LH++ + G + L+ +G + D T P
Sbjct: 261 ALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNT---P 317
Query: 157 LHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
LH AA + LI GAD G+ PLH A L+ + ++LL +G DTP
Sbjct: 318 LHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPD 377
Query: 216 VFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
F T LH AA+ G+ C KLL ++GAD G+ T LH AA + H C L+ G
Sbjct: 378 KFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGR-TPLHYAAANCHFHCIETLVTTG 436
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAI-VRGARACD 334
A+++ + G+T LH A + +DR + D L A ++ A
Sbjct: 437 ANVNETDDWGRTALHYAAASD--------MDRNKTILGNAHDNSEELERARELKEKEATL 488
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
LL A+P+ D GY +H AA C+ L
Sbjct: 489 CLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLEL 525
Score = 97.9 bits (233), Expect = 1e-19
Identities = 69/210 (32%), Positives = 107/210 (50%), Gaps = 4/210 (1%)
Query: 171 VLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLG 229
+LI DVN S+ R+PLH A E+++ L+ +GA + TPLH A +
Sbjct: 1 MLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASR 60
Query: 230 SASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPL 289
S ++L+ ADV A T LH+AA + +CA +++ + ++ + G+T L
Sbjct: 61 SEEAVQVLIKHSADVNAR-DKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTAL 119
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
H A L +E+V +L+ + A++ A D R LH A G D+ LL++ GA+
Sbjct: 120 HHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMG--HLDVVALLINHGAEVTCK 177
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
D GYTPLH AA N V LL+ G ++
Sbjct: 178 DKKGYTPLHAAASNGQINVVKHLLNLGVEI 207
>AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens
cDNA FLJ39767 fis, clone SPLEN2000607, weakly similar to
ANKYRIN 1. ).
Length = 919
Score = 153 bits (372), Expect = 2e-36
Identities = 98/264 (37%), Positives = 136/264 (51%), Gaps = 8/264 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH-CAA 161
LL +GV+ DE++ G T LH++C G + V L+D+GA+ N TPLH AA
Sbjct: 200 LLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVN---QPNNNGFTPLHFAAA 256
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
S C+++L+ +GADVN D +SPLH + + L++ G D T
Sbjct: 257 STHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNT 316
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLHVAA G L +GAD A G LHLAA + H++C R LL G ID
Sbjct: 317 PLHVAARYGHELLINTLRTSGADT-AKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDT 375
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P+ G+T LH A ++E +++L AD KD GRTPLH A C L+
Sbjct: 376 PDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHC--IETLV 433
Query: 341 SAGADPNAADNFGYTPLHIAALNE 364
+ GA+ N D++G T LH AA ++
Sbjct: 434 TTGANVNETDDWGRTALHYAAASD 457
Score = 136 bits (329), Expect = 3e-31
Identities = 92/250 (36%), Positives = 134/250 (53%), Gaps = 7/250 (2%)
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVK 202
NT DS K TPLH AA +++LI GA VNA + +PLH AV S + E V+
Sbjct: 10 NTLDSE---KRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQ 66
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L++ A + +TPLHVAA+ + C ++++ + V + G+ TALH AA +
Sbjct: 67 VLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGR-TALHHAALN 125
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E LLL GA+I+ + + + LH A L+VV +L++ A+V KD G TPL
Sbjct: 126 GHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPL 185
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A G ++ + LL+ G + + + +G T LHIA N A V L+DYG +V
Sbjct: 186 HAAASNGQ--INVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQP 243
Query: 383 TNGGVSALSF 392
N G + L F
Sbjct: 244 NNNGFTPLHF 253
Score = 133 bits (322), Expect = 2e-30
Identities = 102/312 (32%), Positives = 150/312 (48%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D+ T LH + SEE V++L+ H A N
Sbjct: 17 RTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 76
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C +V+I + VN + R+ LH+A L+ E+V
Sbjct: 77 ARDKNWQ---TPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNL 133
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + LH AA +G LL+N GA+V G T LH AA +G
Sbjct: 134 LLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG-YTPLHAAASNG 192
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LL+ G ID N G T LH+A VV L+D A+V + +G TPLH
Sbjct: 193 QINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLH 252
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL++ GAD N G +PLH+ A++ L+ GG++
Sbjct: 253 FAAASTHGALCL-ELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVD 311
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 312 KDGNTPLHVAAR 323
Score = 131 bits (316), Expect = 1e-29
Identities = 102/312 (32%), Positives = 144/312 (46%), Gaps = 8/312 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G RTA+ A G ++ LL G + + D R LH + +G + V LL++HGA
Sbjct: 114 GGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 173
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVV 201
D + TPLH AAS + VK L+ G +++ + + LH A + VV
Sbjct: 174 VTCKD---KKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 230
Query: 202 KELLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAA 260
EL++ GA + P TPLH AAS A C +LL+N GADV GK + LH+ A
Sbjct: 231 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGK-SPLHMTA 289
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
G ++ L+ +G ID + G TPLH+A ++ L AD
Sbjct: 290 VHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMF 349
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
PLH A + C R LLS+G + + D FG T LH AA C+ LL G D
Sbjct: 350 PLHLAALNAHSDC--CRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFH 407
Query: 381 LRTNGGVSALSF 392
+ G + L +
Sbjct: 408 KKDKCGRTPLHY 419
Score = 129 bits (312), Expect = 3e-29
Identities = 94/268 (35%), Positives = 129/268 (48%), Gaps = 8/268 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + L G E V LLL GA+ N +D + +A LH AA L V +LI
Sbjct: 112 DRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKK-DRRA--LHWAAYMGHLDVVALLI 168
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
HGA+V +PLH A + VVK LL G D V+ T LH+A G +
Sbjct: 169 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDA 228
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGH-AECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ GA+V G T LH AA H A C LL+++GA ++ + G++PLH+
Sbjct: 229 VVNELIDYGANVNQPNNNG-FTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
+ + L+ ++ D DG TPLH A G + L ++GAD
Sbjct: 288 TAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHEL--LINTLRTSGADTAKCGI 345
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDV 379
PLH+AALN S C LL G ++
Sbjct: 346 HSMFPLHLAALNAHSDCCRKLLSSGFEI 373
Score = 116 bits (280), Expect = 2e-25
Identities = 89/281 (31%), Positives = 133/281 (47%), Gaps = 14/281 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ +P D G +H + G +C++LLL+ + +S + +PLH AA
Sbjct: 493 LLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLER-TNSGFEESDSGATKSPLHLAAY 551
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE-T 220
++VL+ D++ R+ L A E V+ L+ GA T+ T
Sbjct: 552 NGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINPGASIFVKDNVTKRT 611
Query: 221 PLHVAASLGSASCTKLLLNAG-----ADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
PLH + G C +LLL DV+ A G T L LA GH + LLL+
Sbjct: 612 PLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQ---TPLMLAVAYGHIDAVSLLLEKE 668
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI 335
A++D + G T LH + E V+ML+++ + KD+ GRTPLH A RG A +
Sbjct: 669 ANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARG-HATWL 727
Query: 336 ARLLLSAGADPNAA--DNFGYTPLHIAALNEFSACVLLLLD 374
+ LL A ++ + DN GYTPLH A N C+ +LL+
Sbjct: 728 SELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLE 768
Score = 114 bits (275), Expect = 9e-25
Identities = 97/310 (31%), Positives = 137/310 (44%), Gaps = 8/310 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R A+ WA ++G ++ L+ G + D G T LH + G VK LL+ G
Sbjct: 149 RRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEI- 207
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKE 203
D T LH A A V LI +GA+VN ++ +PLH+A S + E
Sbjct: 208 --DEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLE 265
Query: 204 LL-EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + ++PLH+ A G + ++ L+ G ++ G T LH+AA
Sbjct: 266 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGN-TPLHVAARY 324
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH L GA PLHLA L + L+ ++ D GRT L
Sbjct: 325 GHELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCL 384
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
H A G C +LL S+GAD + D G TPLH AA N C+ L+ G +V
Sbjct: 385 HAAAAGGNVEC--IKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNET 442
Query: 383 TNGGVSALSF 392
+ G +AL +
Sbjct: 443 DDWGRTALHY 452
Score = 109 bits (263), Expect = 3e-23
Identities = 87/277 (31%), Positives = 128/277 (46%), Gaps = 15/277 (5%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
KLL G + D D GRTCLH + G+ EC+KLL GA + + TPLH AA
Sbjct: 365 KLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGA---DFHKKDKCGRTPLHYAA 421
Query: 162 SAKSLACVKVLIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTET 220
+ C++ L+ GA+VN R+ LHYA SD + K +L G D +
Sbjct: 422 ANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDM-DRNKTIL--GNAHDNSEELERA 478
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD--HGAHI 278
+ C + LL A+ G ++H AA GH +C LLL+ +
Sbjct: 479 --RELKEKEATLCLEFLLQNDANPSIRDKEG-YNSIHYAAAYGHRQCLELLLERTNSGFE 535
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ + ++PLHLA + +E+L+ D+ +D GRT L A +G C
Sbjct: 536 ESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTEC--VEA 593
Query: 339 LLSAGADPNAADNF-GYTPLHIAALNEFSACVLLLLD 374
L++ GA DN TPLH + +N + C+ LLL+
Sbjct: 594 LINPGASIFVKDNVTKRTPLHASVINGHTLCLRLLLE 630
Score = 107 bits (257), Expect = 1e-22
Identities = 99/324 (30%), Positives = 146/324 (45%), Gaps = 18/324 (5%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E++ G ++ + A + G L LL+ VD D D+ GRT L L+ G ECV+ L
Sbjct: 536 ESDSG-ATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEAL 594
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA----GLSDRSPLHYA 192
++ GA + + TK TPLH + C+++L+ + A ++PL A
Sbjct: 595 INPGA--SIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLA 652
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
V + V LLE A DT + T LH G C ++LL + G+
Sbjct: 653 VAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGR 712
Query: 253 ATALHLAAEDGHAECARLLLDHGAHID---WPNFRGQTPLHLATLAQSLEVVEMLVD-RC 308
T LH AA GHA LL + + + +G TPLH A + +E+L++ +C
Sbjct: 713 -TPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKC 771
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSA--GADPNAADNFGYTPLHIAALNEFS 366
R + TPLH AI+ C A LLL A + + D+ G TPL AA +
Sbjct: 772 --FRKFIGNPFTPLHCAIINDHGNC--ASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHV 827
Query: 367 ACVLLLLDYGGDVTLRTNGGVSAL 390
C+ LLL + V N G +AL
Sbjct: 828 ECLQLLLRHSAPVNAVDNSGKTAL 851
Score = 103 bits (247), Expect = 2e-21
Identities = 98/298 (32%), Positives = 141/298 (47%), Gaps = 19/298 (6%)
Query: 95 GKSILLFKLLKMGVDPDELD--DA-GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
G ++ L LL++ +P+ +D DA G+T L L+ G + V LLL+ A+ +T D
Sbjct: 620 GHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDI--- 676
Query: 152 TKATPLHCAASAKSLACVKVLIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGAC 210
T LH CV++L+ + S R+PLHYA + ELL+ A
Sbjct: 677 LGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQM-AL 735
Query: 211 PDTPQVFTE----TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE 266
+ F + TPLH A G+ +C ++LL R +G T LH A + H
Sbjct: 736 SEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKC-FRKFIG-NPFTPLHCAIINDHGN 793
Query: 267 CARLLLD--HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
CA LLL + + + +G+TPL A A +E +++L+ A V A D G+T L
Sbjct: 794 CASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMM 853
Query: 325 AIVRG-ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A G A A DI L+ SA AD D TPLH+A C LL+LD D +L
Sbjct: 854 AAENGQAGAVDI--LVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESL 909
Score = 97.9 bits (233), Expect = 1e-19
Identities = 69/210 (32%), Positives = 107/210 (50%), Gaps = 4/210 (1%)
Query: 171 VLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLG 229
+LI DVN S+ R+PLH A E+++ L+ +GA + TPLH A +
Sbjct: 1 MLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASR 60
Query: 230 SASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPL 289
S ++L+ ADV A T LH+AA + +CA +++ + ++ + G+T L
Sbjct: 61 SEEAVQVLIKHSADVNAR-DKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTAL 119
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
H A L +E+V +L+ + A++ A D R LH A G D+ LL++ GA+
Sbjct: 120 HHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMG--HLDVVALLINHGAEVTCK 177
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
D GYTPLH AA N V LL+ G ++
Sbjct: 178 DKKGYTPLHAAASNGQINVVKHLLNLGVEI 207
Score = 94.3 bits (224), Expect = 1e-18
Identities = 87/303 (28%), Positives = 137/303 (45%), Gaps = 22/303 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+ G + +E DD GRT LH + + +L AH N S +A L
Sbjct: 432 LVTTGANVNETDDWGRTALHYAAASDMDRNKTIL--GNAHDN---SEELERARELK---E 483
Query: 163 AKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEA--GACPDTPQVF 217
++ C++ L+ + D N + D+ + +HYA + ++ LLE ++
Sbjct: 484 KEATLCLEFLLQN--DANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGA 541
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
T++PLH+AA G ++LL + D+ G+ TAL LAA GH EC L++ GA
Sbjct: 542 TKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGR-TALDLAAFKGHTECVEALINPGAS 600
Query: 278 IDWP-NFRGQTPLHLATL---AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
I N +TPLH + + L ++ + D V KDA G+TPL A+ G
Sbjct: 601 IFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGH--I 658
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFI 393
D LLL A+ + D G T LH + CV +LL+ + + + G + L +
Sbjct: 659 DAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYA 718
Query: 394 VRR 396
R
Sbjct: 719 AAR 721
>X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2)
protein.
Length = 1719
Score = 152 bits (368), Expect = 5e-36
Identities = 112/321 (34%), Positives = 152/321 (47%), Gaps = 10/321 (3%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A GF T + AC ++ LLK G D + ++G T LH++ +G VK
Sbjct: 366 SRALNGF---TPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKN 422
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVL 194
LL GA PN + ET PLH AA A K L+ + A VNA D++PLH A
Sbjct: 423 LLQRGASPNVSNVKVET---PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAAR 479
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VK LLE A P+ TPLH+AA G LL A +A M T
Sbjct: 480 IGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEAS-QACMTKKGFT 538
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH+AA+ G A LLL+ AH + G TPLH+A +L++V++L+ R +
Sbjct: 539 PLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+G TPLH I ++AR LL G NA G TPLH+AA + V LLL
Sbjct: 599 AWNGYTPLH--IAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLS 656
Query: 375 YGGDVTLRTNGGVSALSFIVR 395
+ L G++ L + +
Sbjct: 657 KQANGNLGNKSGLTPLHLVAQ 677
Score = 151 bits (367), Expect = 7e-36
Identities = 106/289 (36%), Positives = 142/289 (49%), Gaps = 7/289 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P+ G T LH++C ++LLL GA + D+ TE+ TPLH A+
Sbjct: 357 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA---SIDAVTESGLTPLHVASF 413
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
L VK L+ GA N + + +PLH A + EV K LL+ A + +TP
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 473
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AA +G + KLLL A+ A G T LH+AA +GH E LL+ A
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGH-TPLHIAAREGHVETVLALLEKEASQACM 532
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLH+A + V E+L++R A A +G TPLH A+ DI +LLL
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH--NNLDIVKLLLP 590
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G P++ GYTPLHIAA LL YGG + GV+ L
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Score = 147 bits (355), Expect = 2e-34
Identities = 102/297 (34%), Positives = 144/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G I++ LL G + T LH + G ++LLDHGA + T+
Sbjct: 250 GNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA---PIQAKTKNGL 306
Query: 155 TPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
+P+H AA L CV++L+ + A+++ L +PLH A V K LL+ GA P++
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 366
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPLH+A +LLL GA + A G T LH+A+ GH + LL
Sbjct: 367 RALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESG-LTPLHVASFMGHLPIVKNLLQ 425
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
GA + N + +TPLH+A A EV + L+ A V AK D +TPLH A G
Sbjct: 426 RGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG--HT 483
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
++ +LLL A+PN A G+TPLHIAA VL LL+ T G + L
Sbjct: 484 NMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540
Score = 147 bits (355), Expect = 2e-34
Identities = 105/307 (34%), Positives = 144/307 (46%), Gaps = 7/307 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ + D++ T LH++ G K+LLD GA PN S TPLH A
Sbjct: 324 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPN---SRALNGFTPLHIACK 380
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ GA ++A S +PLH A +VK LL+ GA P+ V ETP
Sbjct: 381 KNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETP 440
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G K LL A V A + T LH AA GH +LLL++ A+ +
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ-TPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A +E V L+++ A G TPLH A G +A LLL
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK--VRVAELLLE 557
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
A PNAA G TPLH+A + V LLL GG G + L ++ +
Sbjct: 558 RDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEV 617
Query: 402 PRYLCKF 408
R L ++
Sbjct: 618 ARSLLQY 624
Score = 143 bits (346), Expect = 2e-33
Identities = 91/245 (37%), Positives = 128/245 (52%), Gaps = 7/245 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G T LH++ G +LLL+ AHPN ++ + TPLH A +L VK+L+ G
Sbjct: 536 GFTPLHVAAKYGKVRVAELLLERDAHPN---AAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 177 ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
++ + +PLH A + EV + LL+ G + V TPLH+AA G A
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 652
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL+ A+ G T LHL A++GH A +L+ HG +D G TPLH+A+
Sbjct: 653 LLLSKQANGNLGNKSG-LTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHY 711
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
++++V+ L+ ADV AK G +PLH A +G DI LLL GA PN + G T
Sbjct: 712 GNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQG--HTDIVTLLLKNGASPNEVSSDGTT 769
Query: 356 PLHIA 360
PL IA
Sbjct: 770 PLAIA 774
Score = 140 bits (339), Expect = 2e-32
Identities = 105/312 (33%), Positives = 147/312 (47%), Gaps = 7/312 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T + A +G + ++ LL+ +P+ AG T LH++ G E V LL+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEA--- 527
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T+ TPLH AA + ++L+ A NA G + +PLH AV + ++VK
Sbjct: 528 SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKL 587
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL G P +P TPLH+AA + LL G A G T LHLAA++G
Sbjct: 588 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQG-VTPLHLAAQEG 646
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
HAE LLL A+ + N G TPLHL + V ++L+ V A G TPLH
Sbjct: 647 HAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLH 706
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G + + LL AD NA GY+PLH AA + V LLL G +
Sbjct: 707 VASHYGN--IKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS 764
Query: 384 NGGVSALSFIVR 395
+ G + L+ R
Sbjct: 765 SDGTTPLAIAKR 776
Score = 125 bits (302), Expect = 5e-28
Identities = 97/288 (33%), Positives = 136/288 (47%), Gaps = 11/288 (3%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K V+ DD +T LH + +G VKLLL++ A+PN +T TPLH AA
Sbjct: 460 KAKVNAKAKDD--QTPLHCAARIGHTNMVKLLLENNANPNL---ATTAGHTPLHIAAREG 514
Query: 165 SLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
+ V L+ A A ++ + +PLH A V + LLE A P+ TPL
Sbjct: 515 HVETVLALLEKEAS-QACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL 573
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
HVA + KLLL G + G T LH+AA+ E AR LL +G + +
Sbjct: 574 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGY-TPLHIAAKQNQVEVARSLLQYGGSANAES 632
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
+G TPLHLA E+V +L+ + A+ + G TPLH +V +A +L+
Sbjct: 633 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH--LVAQEGHVPVADVLIKH 690
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G +A GYTPLH+A+ V LL + DV +T G S L
Sbjct: 691 GVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPL 738
Score = 124 bits (300), Expect = 9e-28
Identities = 91/284 (32%), Positives = 141/284 (49%), Gaps = 15/284 (5%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
++ +LL + + G T LH++ L G +E V+ L+++GA+ N + ++ TPL+
Sbjct: 60 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVN---AQSQKGFTPLY 116
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
AA L VK L+ +GA+ N D +PL A+ VV L+ G T
Sbjct: 117 MAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG----TKGKV 172
Query: 218 TETPLHVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
LH+AA +LL + DV + G T LH+AA + A+LLL+ G
Sbjct: 173 RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTG---FTPLHIAAHYENLNVAQLLLNRG 229
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI 335
A +++ G TPLH+A+ ++ +V +L+DR A + K D TPLH A G I
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNG--HVRI 287
Query: 336 ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ +LL GA A G +P+H+AA + CV LLL Y ++
Sbjct: 288 SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEI 331
Score = 121 bits (291), Expect = 1e-26
Identities = 86/260 (33%), Positives = 128/260 (49%), Gaps = 7/260 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ +PD L G T LH++ + +LLL+ GA N + + TPLH A+
Sbjct: 192 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNF---TPQNGITPLHIASR 248
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ V++L+ GA + D +PLH A + + + LL+ GA +P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H+AA C +LLL A++ + T LH+AA GH A++LLD GA +
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDD-ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A + V+E+L+ A + A G TPLH A G I + LL
Sbjct: 368 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMG--HLPIVKNLLQ 425
Query: 342 AGADPNAADNFGYTPLHIAA 361
GA PN ++ TPLH+AA
Sbjct: 426 RGASPNVSNVKVETPLHMAA 445
Score = 119 bits (287), Expect = 3e-26
Identities = 90/290 (31%), Positives = 138/290 (47%), Gaps = 13/290 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + + G T L ++ G E V L+++G + + + LH AA
Sbjct: 130 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG-------TKGKVRLPALHIAAR 182
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTET 220
VL+ + + + + +PLH A + V + LL GA + TPQ T
Sbjct: 183 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGI-T 241
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+A+ G+ +LLL+ GA + + T LH AA +GH + +LLDHGA I
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKT-KDELTPLHCAARNGHVRISEILLDHGAPIQA 300
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G +P+H+A L+ V +L+ A++ D TPLH A G +A++LL
Sbjct: 301 KTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHR--VAKVLL 358
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA PN+ G+TPLHIA + LLL G + T G++ L
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPL 408
Score = 118 bits (285), Expect = 6e-26
Identities = 98/311 (31%), Positives = 141/311 (45%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G+ ++ +L+ G + + G T L+++ E VK LL++GA+ N
Sbjct: 80 TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNV 139
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V LI +G L LH A +D LL
Sbjct: 140 ---ATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP---ALHIAARNDDTRTAAVLL 193
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ PD TPLH+AA + + +LLLN GA V G T LH+A+ G+
Sbjct: 194 QNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNG-ITPLHIASRRGNV 252
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
RLLLD GA I+ TPLH A + + E+L+D A ++AK +G +P+H A
Sbjct: 253 IMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMA 312
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
+G D RLLL A+ + TPLH+AA +LLD G R
Sbjct: 313 -AQGDHL-DCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 371 GFTPLHIACKK 381
Score = 84.2 bits (199), Expect = 2e-15
Identities = 65/203 (32%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P G T LH++ E + LL +G N + + TPLH AA
Sbjct: 588 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSAN---AESVQGVTPLHLAAQ 644
Query: 163 AKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V +L++ A+ N G S +PLH V L++ G D TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA+ G+ K LL ADV A G + LH AA+ GH + LLL +GA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP-LHQAAQQGHTDIVTLLLKNGASPNEV 763
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G TPL +A + V ++L
Sbjct: 764 SSDGTTPLAIAKRLGYISVTDVL 786
Score = 80.6 bits (190), Expect = 2e-14
Identities = 72/236 (30%), Positives = 107/236 (45%), Gaps = 12/236 (5%)
Query: 173 IAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ +G D+N + + LH A ++V ELL +T T LH+AA G
Sbjct: 32 LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQD 91
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
+ L+N GA+V A G T L++AA++ H E + LL++GA+ + G TPL +
Sbjct: 92 EVVRELVNYGANVNAQSQKG-FTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAV 150
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI--ARLLLSAGADPNAA 349
A VV L++ + R P A+ AR D A +LL +P+
Sbjct: 151 ALQQGHENVVAHLINYGTKGKV-----RLP---ALHIAARNDDTRTAAVLLQNDPNPDVL 202
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
G+TPLHIAA E LLL+ G V G++ L RR ++ R L
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258
Score = 65.7 bits (153), Expect = 6e-10
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
++ AE G+ T + A G + ++ LL + + + +G T LHL G
Sbjct: 627 SANAESVQGV-TPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVAD 685
Query: 135 LLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLS-DRSPLHYAV 193
+L+ HG D++T TPLH A+ ++ VK L+ H ADVNA SPLH A
Sbjct: 686 VLIKHGVMV---DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAA 742
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
++V LL+ GA P+ TPL +A LG S T +L
Sbjct: 743 QQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 59.3 bits (137), Expect = 5e-08
Identities = 43/156 (27%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
AT+ AA G+ + A L +G I+ N G LHLA+ +++V L+ + +
Sbjct: 13 ATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
G T LH A + G ++ R L++ GA+ NA G+TPL++AA V L
Sbjct: 73 TTTKKGNTALHIAALAGQD--EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 373 LDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKF 408
L+ G + + T G + L+ +++ + + +L +
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 166
>X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for
ankyrin (variant 2.1). ).
Length = 1881
Score = 152 bits (368), Expect = 5e-36
Identities = 112/321 (34%), Positives = 152/321 (47%), Gaps = 10/321 (3%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A GF T + AC ++ LLK G D + ++G T LH++ +G VK
Sbjct: 366 SRALNGF---TPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKN 422
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVL 194
LL GA PN + ET PLH AA A K L+ + A VNA D++PLH A
Sbjct: 423 LLQRGASPNVSNVKVET---PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAAR 479
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VK LLE A P+ TPLH+AA G LL A +A M T
Sbjct: 480 IGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEAS-QACMTKKGFT 538
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH+AA+ G A LLL+ AH + G TPLH+A +L++V++L+ R +
Sbjct: 539 PLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+G TPLH I ++AR LL G NA G TPLH+AA + V LLL
Sbjct: 599 AWNGYTPLH--IAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLS 656
Query: 375 YGGDVTLRTNGGVSALSFIVR 395
+ L G++ L + +
Sbjct: 657 KQANGNLGNKSGLTPLHLVAQ 677
Score = 151 bits (367), Expect = 7e-36
Identities = 106/289 (36%), Positives = 142/289 (49%), Gaps = 7/289 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P+ G T LH++C ++LLL GA + D+ TE+ TPLH A+
Sbjct: 357 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA---SIDAVTESGLTPLHVASF 413
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
L VK L+ GA N + + +PLH A + EV K LL+ A + +TP
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 473
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AA +G + KLLL A+ A G T LH+AA +GH E LL+ A
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGH-TPLHIAAREGHVETVLALLEKEASQACM 532
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLH+A + V E+L++R A A +G TPLH A+ DI +LLL
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH--NNLDIVKLLLP 590
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G P++ GYTPLHIAA LL YGG + GV+ L
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Score = 147 bits (355), Expect = 2e-34
Identities = 102/297 (34%), Positives = 144/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G I++ LL G + T LH + G ++LLDHGA + T+
Sbjct: 250 GNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA---PIQAKTKNGL 306
Query: 155 TPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
+P+H AA L CV++L+ + A+++ L +PLH A V K LL+ GA P++
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 366
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPLH+A +LLL GA + A G T LH+A+ GH + LL
Sbjct: 367 RALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESG-LTPLHVASFMGHLPIVKNLLQ 425
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
GA + N + +TPLH+A A EV + L+ A V AK D +TPLH A G
Sbjct: 426 RGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG--HT 483
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
++ +LLL A+PN A G+TPLHIAA VL LL+ T G + L
Sbjct: 484 NMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540
Score = 147 bits (355), Expect = 2e-34
Identities = 105/307 (34%), Positives = 144/307 (46%), Gaps = 7/307 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ + D++ T LH++ G K+LLD GA PN S TPLH A
Sbjct: 324 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPN---SRALNGFTPLHIACK 380
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ GA ++A S +PLH A +VK LL+ GA P+ V ETP
Sbjct: 381 KNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETP 440
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G K LL A V A + T LH AA GH +LLL++ A+ +
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ-TPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A +E V L+++ A G TPLH A G +A LLL
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK--VRVAELLLE 557
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
A PNAA G TPLH+A + V LLL GG G + L ++ +
Sbjct: 558 RDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEV 617
Query: 402 PRYLCKF 408
R L ++
Sbjct: 618 ARSLLQY 624
Score = 143 bits (346), Expect = 2e-33
Identities = 91/245 (37%), Positives = 128/245 (52%), Gaps = 7/245 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G T LH++ G +LLL+ AHPN ++ + TPLH A +L VK+L+ G
Sbjct: 536 GFTPLHVAAKYGKVRVAELLLERDAHPN---AAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 177 ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
++ + +PLH A + EV + LL+ G + V TPLH+AA G A
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 652
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL+ A+ G T LHL A++GH A +L+ HG +D G TPLH+A+
Sbjct: 653 LLLSKQANGNLGNKSG-LTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHY 711
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
++++V+ L+ ADV AK G +PLH A +G DI LLL GA PN + G T
Sbjct: 712 GNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQG--HTDIVTLLLKNGASPNEVSSDGTT 769
Query: 356 PLHIA 360
PL IA
Sbjct: 770 PLAIA 774
Score = 140 bits (339), Expect = 2e-32
Identities = 105/312 (33%), Positives = 147/312 (47%), Gaps = 7/312 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T + A +G + ++ LL+ +P+ AG T LH++ G E V LL+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEA--- 527
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T+ TPLH AA + ++L+ A NA G + +PLH AV + ++VK
Sbjct: 528 SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKL 587
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL G P +P TPLH+AA + LL G A G T LHLAA++G
Sbjct: 588 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQG-VTPLHLAAQEG 646
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
HAE LLL A+ + N G TPLHL + V ++L+ V A G TPLH
Sbjct: 647 HAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLH 706
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G + + LL AD NA GY+PLH AA + V LLL G +
Sbjct: 707 VASHYGN--IKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS 764
Query: 384 NGGVSALSFIVR 395
+ G + L+ R
Sbjct: 765 SDGTTPLAIAKR 776
Score = 125 bits (302), Expect = 5e-28
Identities = 97/288 (33%), Positives = 136/288 (47%), Gaps = 11/288 (3%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K V+ DD +T LH + +G VKLLL++ A+PN +T TPLH AA
Sbjct: 460 KAKVNAKAKDD--QTPLHCAARIGHTNMVKLLLENNANPNL---ATTAGHTPLHIAAREG 514
Query: 165 SLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
+ V L+ A A ++ + +PLH A V + LLE A P+ TPL
Sbjct: 515 HVETVLALLEKEAS-QACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL 573
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
HVA + KLLL G + G T LH+AA+ E AR LL +G + +
Sbjct: 574 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGY-TPLHIAAKQNQVEVARSLLQYGGSANAES 632
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
+G TPLHLA E+V +L+ + A+ + G TPLH +V +A +L+
Sbjct: 633 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH--LVAQEGHVPVADVLIKH 690
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G +A GYTPLH+A+ V LL + DV +T G S L
Sbjct: 691 GVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPL 738
Score = 124 bits (300), Expect = 9e-28
Identities = 91/284 (32%), Positives = 141/284 (49%), Gaps = 15/284 (5%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
++ +LL + + G T LH++ L G +E V+ L+++GA+ N + ++ TPL+
Sbjct: 60 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVN---AQSQKGFTPLY 116
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
AA L VK L+ +GA+ N D +PL A+ VV L+ G T
Sbjct: 117 MAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG----TKGKV 172
Query: 218 TETPLHVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
LH+AA +LL + DV + G T LH+AA + A+LLL+ G
Sbjct: 173 RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTG---FTPLHIAAHYENLNVAQLLLNRG 229
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI 335
A +++ G TPLH+A+ ++ +V +L+DR A + K D TPLH A G I
Sbjct: 230 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNG--HVRI 287
Query: 336 ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ +LL GA A G +P+H+AA + CV LLL Y ++
Sbjct: 288 SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEI 331
Score = 121 bits (291), Expect = 1e-26
Identities = 86/260 (33%), Positives = 128/260 (49%), Gaps = 7/260 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ +PD L G T LH++ + +LLL+ GA N + + TPLH A+
Sbjct: 192 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNF---TPQNGITPLHIASR 248
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ V++L+ GA + D +PLH A + + + LL+ GA +P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H+AA C +LLL A++ + T LH+AA GH A++LLD GA +
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDD-ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A + V+E+L+ A + A G TPLH A G I + LL
Sbjct: 368 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMG--HLPIVKNLLQ 425
Query: 342 AGADPNAADNFGYTPLHIAA 361
GA PN ++ TPLH+AA
Sbjct: 426 RGASPNVSNVKVETPLHMAA 445
Score = 119 bits (287), Expect = 3e-26
Identities = 90/290 (31%), Positives = 138/290 (47%), Gaps = 13/290 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + + G T L ++ G E V L+++G + + + LH AA
Sbjct: 130 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG-------TKGKVRLPALHIAAR 182
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTET 220
VL+ + + + + +PLH A + V + LL GA + TPQ T
Sbjct: 183 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGI-T 241
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+A+ G+ +LLL+ GA + + T LH AA +GH + +LLDHGA I
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKT-KDELTPLHCAARNGHVRISEILLDHGAPIQA 300
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G +P+H+A L+ V +L+ A++ D TPLH A G +A++LL
Sbjct: 301 KTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHR--VAKVLL 358
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA PN+ G+TPLHIA + LLL G + T G++ L
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPL 408
Score = 118 bits (285), Expect = 6e-26
Identities = 98/311 (31%), Positives = 141/311 (45%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G+ ++ +L+ G + + G T L+++ E VK LL++GA+ N
Sbjct: 80 TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNV 139
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V LI +G L LH A +D LL
Sbjct: 140 ---ATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP---ALHIAARNDDTRTAAVLL 193
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ PD TPLH+AA + + +LLLN GA V G T LH+A+ G+
Sbjct: 194 QNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNG-ITPLHIASRRGNV 252
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
RLLLD GA I+ TPLH A + + E+L+D A ++AK +G +P+H A
Sbjct: 253 IMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMA 312
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
+G D RLLL A+ + TPLH+AA +LLD G R
Sbjct: 313 -AQGDHL-DCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 371 GFTPLHIACKK 381
Score = 84.2 bits (199), Expect = 2e-15
Identities = 65/203 (32%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P G T LH++ E + LL +G N + + TPLH AA
Sbjct: 588 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSAN---AESVQGVTPLHLAAQ 644
Query: 163 AKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V +L++ A+ N G S +PLH V L++ G D TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA+ G+ K LL ADV A G + LH AA+ GH + LLL +GA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP-LHQAAQQGHTDIVTLLLKNGASPNEV 763
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G TPL +A + V ++L
Sbjct: 764 SSDGTTPLAIAKRLGYISVTDVL 786
Score = 80.6 bits (190), Expect = 2e-14
Identities = 72/236 (30%), Positives = 107/236 (45%), Gaps = 12/236 (5%)
Query: 173 IAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ +G D+N + + LH A ++V ELL +T T LH+AA G
Sbjct: 32 LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQD 91
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
+ L+N GA+V A G T L++AA++ H E + LL++GA+ + G TPL +
Sbjct: 92 EVVRELVNYGANVNAQSQKG-FTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAV 150
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI--ARLLLSAGADPNAA 349
A VV L++ + R P A+ AR D A +LL +P+
Sbjct: 151 ALQQGHENVVAHLINYGTKGKV-----RLP---ALHIAARNDDTRTAAVLLQNDPNPDVL 202
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
G+TPLHIAA E LLL+ G V G++ L RR ++ R L
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 258
Score = 65.7 bits (153), Expect = 6e-10
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
++ AE G+ T + A G + ++ LL + + + +G T LHL G
Sbjct: 627 SANAESVQGV-TPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVAD 685
Query: 135 LLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLS-DRSPLHYAV 193
+L+ HG D++T TPLH A+ ++ VK L+ H ADVNA SPLH A
Sbjct: 686 VLIKHGVMV---DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAA 742
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
++V LL+ GA P+ TPL +A LG S T +L
Sbjct: 743 QQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 59.3 bits (137), Expect = 5e-08
Identities = 43/156 (27%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
AT+ AA G+ + A L +G I+ N G LHLA+ +++V L+ + +
Sbjct: 13 ATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
G T LH A + G ++ R L++ GA+ NA G+TPL++AA V L
Sbjct: 73 TTTKKGNTALHIAALAGQD--EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 373 LDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKF 408
L+ G + + T G + L+ +++ + + +L +
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 166
>U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein.
Length = 1856
Score = 152 bits (368), Expect = 5e-36
Identities = 112/321 (34%), Positives = 152/321 (47%), Gaps = 10/321 (3%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A GF T + AC ++ LLK G D + ++G T LH++ +G VK
Sbjct: 333 SRALNGF---TPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKN 389
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVL 194
LL GA PN + ET PLH AA A K L+ + A VNA D++PLH A
Sbjct: 390 LLQRGASPNVSNVKVET---PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAAR 446
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VK LLE A P+ TPLH+AA G LL A +A M T
Sbjct: 447 IGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEAS-QACMTKKGFT 505
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH+AA+ G A LLL+ AH + G TPLH+A +L++V++L+ R +
Sbjct: 506 PLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 565
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+G TPLH I ++AR LL G NA G TPLH+AA + V LLL
Sbjct: 566 AWNGYTPLH--IAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLS 623
Query: 375 YGGDVTLRTNGGVSALSFIVR 395
+ L G++ L + +
Sbjct: 624 KQANGNLGNKSGLTPLHLVAQ 644
Score = 151 bits (367), Expect = 7e-36
Identities = 106/289 (36%), Positives = 142/289 (49%), Gaps = 7/289 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P+ G T LH++C ++LLL GA + D+ TE+ TPLH A+
Sbjct: 324 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA---SIDAVTESGLTPLHVASF 380
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
L VK L+ GA N + + +PLH A + EV K LL+ A + +TP
Sbjct: 381 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 440
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AA +G + KLLL A+ A G T LH+AA +GH E LL+ A
Sbjct: 441 LHCAARIGHTNMVKLLLENNANPNLATTAGH-TPLHIAAREGHVETVLALLEKEASQACM 499
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLH+A + V E+L++R A A +G TPLH A+ DI +LLL
Sbjct: 500 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH--NNLDIVKLLLP 557
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G P++ GYTPLHIAA LL YGG + GV+ L
Sbjct: 558 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 606
Score = 147 bits (355), Expect = 2e-34
Identities = 102/297 (34%), Positives = 144/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G I++ LL G + T LH + G ++LLDHGA + T+
Sbjct: 217 GNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA---PIQAKTKNGL 273
Query: 155 TPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
+P+H AA L CV++L+ + A+++ L +PLH A V K LL+ GA P++
Sbjct: 274 SPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 333
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPLH+A +LLL GA + A G T LH+A+ GH + LL
Sbjct: 334 RALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESG-LTPLHVASFMGHLPIVKNLLQ 392
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
GA + N + +TPLH+A A EV + L+ A V AK D +TPLH A G
Sbjct: 393 RGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG--HT 450
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
++ +LLL A+PN A G+TPLHIAA VL LL+ T G + L
Sbjct: 451 NMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 507
Score = 147 bits (355), Expect = 2e-34
Identities = 105/307 (34%), Positives = 144/307 (46%), Gaps = 7/307 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ + D++ T LH++ G K+LLD GA PN S TPLH A
Sbjct: 291 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPN---SRALNGFTPLHIACK 347
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ GA ++A S +PLH A +VK LL+ GA P+ V ETP
Sbjct: 348 KNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETP 407
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G K LL A V A + T LH AA GH +LLL++ A+ +
Sbjct: 408 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ-TPLHCAARIGHTNMVKLLLENNANPNLA 466
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A +E V L+++ A G TPLH A G +A LLL
Sbjct: 467 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK--VRVAELLLE 524
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
A PNAA G TPLH+A + V LLL GG G + L ++ +
Sbjct: 525 RDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEV 584
Query: 402 PRYLCKF 408
R L ++
Sbjct: 585 ARSLLQY 591
Score = 143 bits (346), Expect = 2e-33
Identities = 91/245 (37%), Positives = 128/245 (52%), Gaps = 7/245 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G T LH++ G +LLL+ AHPN ++ + TPLH A +L VK+L+ G
Sbjct: 503 GFTPLHVAAKYGKVRVAELLLERDAHPN---AAGKNGLTPLHVAVHHNNLDIVKLLLPRG 559
Query: 177 ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
++ + +PLH A + EV + LL+ G + V TPLH+AA G A
Sbjct: 560 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 619
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL+ A+ G T LHL A++GH A +L+ HG +D G TPLH+A+
Sbjct: 620 LLLSKQANGNLGNKSG-LTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHY 678
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
++++V+ L+ ADV AK G +PLH A +G DI LLL GA PN + G T
Sbjct: 679 GNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQG--HTDIVTLLLKNGASPNEVSSDGTT 736
Query: 356 PLHIA 360
PL IA
Sbjct: 737 PLAIA 741
Score = 140 bits (339), Expect = 2e-32
Identities = 105/312 (33%), Positives = 147/312 (47%), Gaps = 7/312 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T + A +G + ++ LL+ +P+ AG T LH++ G E V LL+ A
Sbjct: 438 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEA--- 494
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T+ TPLH AA + ++L+ A NA G + +PLH AV + ++VK
Sbjct: 495 SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKL 554
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL G P +P TPLH+AA + LL G A G T LHLAA++G
Sbjct: 555 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQG-VTPLHLAAQEG 613
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
HAE LLL A+ + N G TPLHL + V ++L+ V A G TPLH
Sbjct: 614 HAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLH 673
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G + + LL AD NA GY+PLH AA + V LLL G +
Sbjct: 674 VASHYGN--IKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS 731
Query: 384 NGGVSALSFIVR 395
+ G + L+ R
Sbjct: 732 SDGTTPLAIAKR 743
Score = 130 bits (315), Expect = 1e-29
Identities = 93/279 (33%), Positives = 141/279 (50%), Gaps = 15/279 (5%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
L+ GVD + + G T LH++ L G +E V+ L+++GA+ N + ++ TPL+ AA
Sbjct: 32 LRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVN---AQSQKGFTPLYMAAQE 88
Query: 164 KSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
L VK L+ +GA+ N D +PL A+ VV L+ G T L
Sbjct: 89 NHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG----TKGKVRLPAL 144
Query: 223 HVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
H+AA +LL + DV + G T LH+AA + A+LLL+ GA +++
Sbjct: 145 HIAARNDDTRTAAVLLQNDPNPDVLSKTG---FTPLHIAAHYENLNVAQLLLNRGASVNF 201
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G TPLH+A+ ++ +V +L+DR A + K D TPLH A G I+ +LL
Sbjct: 202 TPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNG--HVRISEILL 259
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
GA A G +P+H+AA + CV LLL Y ++
Sbjct: 260 DHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEI 298
Score = 125 bits (302), Expect = 5e-28
Identities = 97/288 (33%), Positives = 136/288 (47%), Gaps = 11/288 (3%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K V+ DD +T LH + +G VKLLL++ A+PN +T TPLH AA
Sbjct: 427 KAKVNAKAKDD--QTPLHCAARIGHTNMVKLLLENNANPNL---ATTAGHTPLHIAAREG 481
Query: 165 SLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
+ V L+ A A ++ + +PLH A V + LLE A P+ TPL
Sbjct: 482 HVETVLALLEKEAS-QACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL 540
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
HVA + KLLL G + G T LH+AA+ E AR LL +G + +
Sbjct: 541 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGY-TPLHIAAKQNQVEVARSLLQYGGSANAES 599
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
+G TPLHLA E+V +L+ + A+ + G TPLH +V +A +L+
Sbjct: 600 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH--LVAQEGHVPVADVLIKH 657
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G +A GYTPLH+A+ V LL + DV +T G S L
Sbjct: 658 GVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPL 705
Score = 121 bits (291), Expect = 1e-26
Identities = 86/260 (33%), Positives = 128/260 (49%), Gaps = 7/260 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ +PD L G T LH++ + +LLL+ GA N + + TPLH A+
Sbjct: 159 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNF---TPQNGITPLHIASR 215
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ V++L+ GA + D +PLH A + + + LL+ GA +P
Sbjct: 216 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 275
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H+AA C +LLL A++ + T LH+AA GH A++LLD GA +
Sbjct: 276 IHMAAQGDHLDCVRLLLQYDAEIDD-ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 334
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A + V+E+L+ A + A G TPLH A G I + LL
Sbjct: 335 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMG--HLPIVKNLLQ 392
Query: 342 AGADPNAADNFGYTPLHIAA 361
GA PN ++ TPLH+AA
Sbjct: 393 RGASPNVSNVKVETPLHMAA 412
Score = 119 bits (287), Expect = 3e-26
Identities = 90/290 (31%), Positives = 138/290 (47%), Gaps = 13/290 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + + G T L ++ G E V L+++G + + + LH AA
Sbjct: 97 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG-------TKGKVRLPALHIAAR 149
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTET 220
VL+ + + + + +PLH A + V + LL GA + TPQ T
Sbjct: 150 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGI-T 208
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+A+ G+ +LLL+ GA + + T LH AA +GH + +LLDHGA I
Sbjct: 209 PLHIASRRGNVIMVRLLLDRGAQIETKT-KDELTPLHCAARNGHVRISEILLDHGAPIQA 267
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G +P+H+A L+ V +L+ A++ D TPLH A G +A++LL
Sbjct: 268 KTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHR--VAKVLL 325
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA PN+ G+TPLHIA + LLL G + T G++ L
Sbjct: 326 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPL 375
Score = 118 bits (285), Expect = 6e-26
Identities = 98/311 (31%), Positives = 141/311 (45%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G+ ++ +L+ G + + G T L+++ E VK LL++GA+ N
Sbjct: 47 TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNV 106
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V LI +G L LH A +D LL
Sbjct: 107 ---ATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP---ALHIAARNDDTRTAAVLL 160
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ PD TPLH+AA + + +LLLN GA V G T LH+A+ G+
Sbjct: 161 QNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNG-ITPLHIASRRGNV 219
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
RLLLD GA I+ TPLH A + + E+L+D A ++AK +G +P+H A
Sbjct: 220 IMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMA 279
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
+G D RLLL A+ + TPLH+AA +LLD G R
Sbjct: 280 -AQGDHL-DCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 337
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 338 GFTPLHIACKK 348
Score = 112 bits (269), Expect = 5e-24
Identities = 87/255 (34%), Positives = 123/255 (48%), Gaps = 8/255 (3%)
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLS 195
LDH + ++ + T LH AA A V+ L+ +GA+VNA +PL+ A
Sbjct: 29 LDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQE 88
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+ EVVK LLE GA + TPL VA G + L+N G G + A
Sbjct: 89 NHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG-----TKGKVRLPA 143
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
LH+AA + A +LL + + D + G TPLH+A ++L V ++L++R A V
Sbjct: 144 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTP 203
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
+G TPLH A RG + RLLL GA TPLH AA N +LLD+
Sbjct: 204 QNGITPLHIASRRG--NVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDH 261
Query: 376 GGDVTLRTNGGVSAL 390
G + +T G+S +
Sbjct: 262 GAPIQAKTKNGLSPI 276
Score = 84.2 bits (199), Expect = 2e-15
Identities = 65/203 (32%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P G T LH++ E + LL +G N + + TPLH AA
Sbjct: 555 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSAN---AESVQGVTPLHLAAQ 611
Query: 163 AKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V +L++ A+ N G S +PLH V L++ G D TP
Sbjct: 612 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 671
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA+ G+ K LL ADV A G + LH AA+ GH + LLL +GA +
Sbjct: 672 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP-LHQAAQQGHTDIVTLLLKNGASPNEV 730
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G TPL +A + V ++L
Sbjct: 731 SSDGTTPLAIAKRLGYISVTDVL 753
Score = 82.2 bits (194), Expect = 6e-15
Identities = 67/225 (29%), Positives = 98/225 (43%), Gaps = 10/225 (4%)
Query: 173 IAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ +G D+N + LH A L+ EVV+EL+ GA + TPL++AA
Sbjct: 32 LRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHL 91
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTP-LH 290
K LL GA+ A G T L +A + GH L+++G + + P LH
Sbjct: 92 EVVKFLLENGANQNVATEDG-FTPLAVALQQGHENVVAHLINYGT-----KGKVRLPALH 145
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
+A +L+ + G TPLH I ++A+LLL+ GA N
Sbjct: 146 IAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLH--IAAHYENLNVAQLLLNRGASVNFTP 203
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
G TPLHIA+ V LLLD G + +T ++ L R
Sbjct: 204 QNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAAR 248
Score = 72.5 bits (170), Expect = 5e-12
Identities = 61/188 (32%), Positives = 88/188 (46%), Gaps = 11/188 (5%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
T LH+AA G + L+N GA+V A G T L++AA++ H E + LL++GA+ +
Sbjct: 47 TALHIAALAGQDEVVRELVNYGANVNAQSQKG-FTPLYMAAQENHLEVVKFLLENGANQN 105
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI--AR 337
G TPL +A VV L++ + R P A+ AR D A
Sbjct: 106 VATEDGFTPLAVALQQGHENVVAHLINYGTKGKV-----RLP---ALHIAARNDDTRTAA 157
Query: 338 LLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRV 397
+LL +P+ G+TPLHIAA E LLL+ G V G++ L RR
Sbjct: 158 VLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRG 217
Query: 398 PDVIPRYL 405
++ R L
Sbjct: 218 NVIMVRLL 225
Score = 66.9 bits (156), Expect = 2e-10
Identities = 45/124 (36%), Positives = 64/124 (51%), Gaps = 2/124 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
AT+ AA G+ + A L +G I+ N +G T LH+A LA EVV LV+ A+V
Sbjct: 13 ATSFLRAARSGNLDKALDHLRNGVDINTCNQKGNTALHIAALAGQDEVVRELVNYGANVN 72
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A+ G TPL+ A ++ + LL GA+ N A G+TPL +A V L
Sbjct: 73 AQSQKGFTPLYMAAQE--NHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL 130
Query: 373 LDYG 376
++YG
Sbjct: 131 INYG 134
Score = 65.7 bits (153), Expect = 6e-10
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
++ AE G+ T + A G + ++ LL + + + +G T LHL G
Sbjct: 594 SANAESVQGV-TPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVAD 652
Query: 135 LLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLS-DRSPLHYAV 193
+L+ HG D++T TPLH A+ ++ VK L+ H ADVNA SPLH A
Sbjct: 653 VLIKHGVMV---DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAA 709
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
++V LL+ GA P+ TPL +A LG S T +L
Sbjct: 710 QQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 753
Score = 45.6 bits (103), Expect = 6e-04
Identities = 27/99 (27%), Positives = 50/99 (50%), Gaps = 2/99 (2%)
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
D+ + G T LH A + G ++ R L++ GA+ NA G+TPL++AA V
Sbjct: 37 DINTCNQKGNTALHIAALAGQD--EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV 94
Query: 370 LLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKF 408
LL+ G + + T G + L+ +++ + + +L +
Sbjct: 95 KFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 133
>M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein.
Length = 1880
Score = 152 bits (368), Expect = 5e-36
Identities = 112/321 (34%), Positives = 152/321 (47%), Gaps = 10/321 (3%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A GF T + AC ++ LLK G D + ++G T LH++ +G VK
Sbjct: 366 SRALNGF---TPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKN 422
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVL 194
LL GA PN + ET PLH AA A K L+ + A VNA D++PLH A
Sbjct: 423 LLQRGASPNVSNVKVET---PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAAR 479
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VK LLE A P+ TPLH+AA G LL A +A M T
Sbjct: 480 IGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEAS-QACMTKKGFT 538
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH+AA+ G A LLL+ AH + G TPLH+A +L++V++L+ R +
Sbjct: 539 PLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+G TPLH I ++AR LL G NA G TPLH+AA + V LLL
Sbjct: 599 AWNGYTPLH--IAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLS 656
Query: 375 YGGDVTLRTNGGVSALSFIVR 395
+ L G++ L + +
Sbjct: 657 KQANGNLGNKSGLTPLHLVAQ 677
Score = 151 bits (367), Expect = 7e-36
Identities = 106/289 (36%), Positives = 142/289 (49%), Gaps = 7/289 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P+ G T LH++C ++LLL GA + D+ TE+ TPLH A+
Sbjct: 357 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA---SIDAVTESGLTPLHVASF 413
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
L VK L+ GA N + + +PLH A + EV K LL+ A + +TP
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 473
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AA +G + KLLL A+ A G T LH+AA +GH E LL+ A
Sbjct: 474 LHCAARIGHTNMVKLLLENNANPNLATTAGH-TPLHIAAREGHVETVLALLEKEASQACM 532
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLH+A + V E+L++R A A +G TPLH A+ DI +LLL
Sbjct: 533 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH--NNLDIVKLLLP 590
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G P++ GYTPLHIAA LL YGG + GV+ L
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Score = 147 bits (355), Expect = 2e-34
Identities = 102/297 (34%), Positives = 144/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G I++ LL G + T LH + G ++LLDHGA + T+
Sbjct: 250 GNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA---PIQAKTKNGL 306
Query: 155 TPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
+P+H AA L CV++L+ + A+++ L +PLH A V K LL+ GA P++
Sbjct: 307 SPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 366
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPLH+A +LLL GA + A G T LH+A+ GH + LL
Sbjct: 367 RALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESG-LTPLHVASFMGHLPIVKNLLQ 425
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
GA + N + +TPLH+A A EV + L+ A V AK D +TPLH A G
Sbjct: 426 RGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG--HT 483
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
++ +LLL A+PN A G+TPLHIAA VL LL+ T G + L
Sbjct: 484 NMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 540
Score = 147 bits (355), Expect = 2e-34
Identities = 105/307 (34%), Positives = 144/307 (46%), Gaps = 7/307 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ + D++ T LH++ G K+LLD GA PN S TPLH A
Sbjct: 324 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPN---SRALNGFTPLHIACK 380
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ GA ++A S +PLH A +VK LL+ GA P+ V ETP
Sbjct: 381 KNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETP 440
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G K LL A V A + T LH AA GH +LLL++ A+ +
Sbjct: 441 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ-TPLHCAARIGHTNMVKLLLENNANPNLA 499
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A +E V L+++ A G TPLH A G +A LLL
Sbjct: 500 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK--VRVAELLLE 557
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
A PNAA G TPLH+A + V LLL GG G + L ++ +
Sbjct: 558 RDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEV 617
Query: 402 PRYLCKF 408
R L ++
Sbjct: 618 ARSLLQY 624
Score = 143 bits (346), Expect = 2e-33
Identities = 91/245 (37%), Positives = 128/245 (52%), Gaps = 7/245 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G T LH++ G +LLL+ AHPN ++ + TPLH A +L VK+L+ G
Sbjct: 536 GFTPLHVAAKYGKVRVAELLLERDAHPN---AAGKNGLTPLHVAVHHNNLDIVKLLLPRG 592
Query: 177 ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
++ + +PLH A + EV + LL+ G + V TPLH+AA G A
Sbjct: 593 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 652
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL+ A+ G T LHL A++GH A +L+ HG +D G TPLH+A+
Sbjct: 653 LLLSKQANGNLGNKSG-LTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHY 711
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
++++V+ L+ ADV AK G +PLH A +G DI LLL GA PN + G T
Sbjct: 712 GNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQG--HTDIVTLLLKNGASPNEVSSDGTT 769
Query: 356 PLHIA 360
PL IA
Sbjct: 770 PLAIA 774
Score = 140 bits (339), Expect = 2e-32
Identities = 105/312 (33%), Positives = 147/312 (47%), Gaps = 7/312 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T + A +G + ++ LL+ +P+ AG T LH++ G E V LL+ A
Sbjct: 471 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEA--- 527
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T+ TPLH AA + ++L+ A NA G + +PLH AV + ++VK
Sbjct: 528 SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKL 587
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL G P +P TPLH+AA + LL G A G T LHLAA++G
Sbjct: 588 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQG-VTPLHLAAQEG 646
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
HAE LLL A+ + N G TPLHL + V ++L+ V A G TPLH
Sbjct: 647 HAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLH 706
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G + + LL AD NA GY+PLH AA + V LLL G +
Sbjct: 707 VASHYGN--IKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS 764
Query: 384 NGGVSALSFIVR 395
+ G + L+ R
Sbjct: 765 SDGTTPLAIAKR 776
Score = 125 bits (302), Expect = 5e-28
Identities = 97/288 (33%), Positives = 136/288 (47%), Gaps = 11/288 (3%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K V+ DD +T LH + +G VKLLL++ A+PN +T TPLH AA
Sbjct: 460 KAKVNAKAKDD--QTPLHCAARIGHTNMVKLLLENNANPNL---ATTAGHTPLHIAAREG 514
Query: 165 SLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
+ V L+ A A ++ + +PLH A V + LLE A P+ TPL
Sbjct: 515 HVETVLALLEKEAS-QACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL 573
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
HVA + KLLL G + G T LH+AA+ E AR LL +G + +
Sbjct: 574 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGY-TPLHIAAKQNQVEVARSLLQYGGSANAES 632
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
+G TPLHLA E+V +L+ + A+ + G TPLH +V +A +L+
Sbjct: 633 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH--LVAQEGHVPVADVLIKH 690
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G +A GYTPLH+A+ V LL + DV +T G S L
Sbjct: 691 GVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPL 738
Score = 123 bits (297), Expect = 2e-27
Identities = 90/284 (31%), Positives = 141/284 (49%), Gaps = 15/284 (5%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
++ +LL + + G T LH++ L G +E V+ L+++GA+ N + ++ TPL+
Sbjct: 60 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVN---AQSQKGFTPLY 116
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
AA L VK L+ +GA+ N D +PL A+ VV L+ G T
Sbjct: 117 MAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG----TKGKV 172
Query: 218 TETPLHVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
LH+AA +LL + DV + G T LH+AA + A+LLL+ G
Sbjct: 173 RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTG---FTPLHIAAHYENLNVAQLLLNRG 229
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI 335
+ +++ G TPLH+A+ ++ +V +L+DR A + K D TPLH A G I
Sbjct: 230 SSVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNG--HVRI 287
Query: 336 ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ +LL GA A G +P+H+AA + CV LLL Y ++
Sbjct: 288 SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEI 331
Score = 120 bits (288), Expect = 2e-26
Identities = 85/260 (32%), Positives = 128/260 (49%), Gaps = 7/260 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ +PD L G T LH++ + +LLL+ G+ N + + TPLH A+
Sbjct: 192 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNF---TPQNGITPLHIASR 248
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ V++L+ GA + D +PLH A + + + LL+ GA +P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 308
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H+AA C +LLL A++ + T LH+AA GH A++LLD GA +
Sbjct: 309 IHMAAQGDHLDCVRLLLQYDAEIDD-ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A + V+E+L+ A + A G TPLH A G I + LL
Sbjct: 368 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMG--HLPIVKNLLQ 425
Query: 342 AGADPNAADNFGYTPLHIAA 361
GA PN ++ TPLH+AA
Sbjct: 426 RGASPNVSNVKVETPLHMAA 445
Score = 118 bits (284), Expect = 8e-26
Identities = 89/290 (30%), Positives = 138/290 (47%), Gaps = 13/290 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + + G T L ++ G E V L+++G + + + LH AA
Sbjct: 130 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG-------TKGKVRLPALHIAAR 182
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTET 220
VL+ + + + + +PLH A + V + LL G+ + TPQ T
Sbjct: 183 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGI-T 241
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+A+ G+ +LLL+ GA + + T LH AA +GH + +LLDHGA I
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKT-KDELTPLHCAARNGHVRISEILLDHGAPIQA 300
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G +P+H+A L+ V +L+ A++ D TPLH A G +A++LL
Sbjct: 301 KTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHR--VAKVLL 358
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA PN+ G+TPLHIA + LLL G + T G++ L
Sbjct: 359 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPL 408
Score = 117 bits (282), Expect = 1e-25
Identities = 97/311 (31%), Positives = 141/311 (45%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G+ ++ +L+ G + + G T L+++ E VK LL++GA+ N
Sbjct: 80 TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNV 139
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V LI +G L LH A +D LL
Sbjct: 140 ---ATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP---ALHIAARNDDTRTAAVLL 193
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ PD TPLH+AA + + +LLLN G+ V G T LH+A+ G+
Sbjct: 194 QNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNG-ITPLHIASRRGNV 252
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
RLLLD GA I+ TPLH A + + E+L+D A ++AK +G +P+H A
Sbjct: 253 IMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMA 312
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
+G D RLLL A+ + TPLH+AA +LLD G R
Sbjct: 313 -AQGDHL-DCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 370
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 371 GFTPLHIACKK 381
Score = 84.2 bits (199), Expect = 2e-15
Identities = 65/203 (32%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P G T LH++ E + LL +G N + + TPLH AA
Sbjct: 588 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSAN---AESVQGVTPLHLAAQ 644
Query: 163 AKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V +L++ A+ N G S +PLH V L++ G D TP
Sbjct: 645 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 704
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA+ G+ K LL ADV A G + LH AA+ GH + LLL +GA +
Sbjct: 705 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP-LHQAAQQGHTDIVTLLLKNGASPNEV 763
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G TPL +A + V ++L
Sbjct: 764 SSDGTTPLAIAKRLGYISVTDVL 786
Score = 80.6 bits (190), Expect = 2e-14
Identities = 72/236 (30%), Positives = 107/236 (45%), Gaps = 12/236 (5%)
Query: 173 IAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ +G D+N + + LH A ++V ELL +T T LH+AA G
Sbjct: 32 LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQD 91
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
+ L+N GA+V A G T L++AA++ H E + LL++GA+ + G TPL +
Sbjct: 92 EVVRELVNYGANVNAQSQKG-FTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAV 150
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI--ARLLLSAGADPNAA 349
A VV L++ + R P A+ AR D A +LL +P+
Sbjct: 151 ALQQGHENVVAHLINYGTKGKV-----RLP---ALHIAARNDDTRTAAVLLQNDPNPDVL 202
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
G+TPLHIAA E LLL+ G V G++ L RR ++ R L
Sbjct: 203 SKTGFTPLHIAAHYENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMVRLL 258
Score = 65.7 bits (153), Expect = 6e-10
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
++ AE G+ T + A G + ++ LL + + + +G T LHL G
Sbjct: 627 SANAESVQGV-TPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVAD 685
Query: 135 LLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLS-DRSPLHYAV 193
+L+ HG D++T TPLH A+ ++ VK L+ H ADVNA SPLH A
Sbjct: 686 VLIKHGVMV---DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAA 742
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
++V LL+ GA P+ TPL +A LG S T +L
Sbjct: 743 QQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 786
Score = 59.3 bits (137), Expect = 5e-08
Identities = 43/156 (27%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
AT+ AA G+ + A L +G I+ N G LHLA+ +++V L+ + +
Sbjct: 13 ATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 72
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
G T LH A + G ++ R L++ GA+ NA G+TPL++AA V L
Sbjct: 73 TTTKKGNTALHIAALAGQD--EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 373 LDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKF 408
L+ G + + T G + L+ +++ + + +L +
Sbjct: 131 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 166
>AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4
variant protein.
Length = 1899
Score = 152 bits (368), Expect = 5e-36
Identities = 112/321 (34%), Positives = 152/321 (47%), Gaps = 10/321 (3%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A GF T + AC ++ LLK G D + ++G T LH++ +G VK
Sbjct: 401 SRALNGF---TPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKN 457
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVL 194
LL GA PN + ET PLH AA A K L+ + A VNA D++PLH A
Sbjct: 458 LLQRGASPNVSNVKVET---PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAAR 514
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VK LLE A P+ TPLH+AA G LL A +A M T
Sbjct: 515 IGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEAS-QACMTKKGFT 573
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH+AA+ G A LLL+ AH + G TPLH+A +L++V++L+ R +
Sbjct: 574 PLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 633
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+G TPLH I ++AR LL G NA G TPLH+AA + V LLL
Sbjct: 634 AWNGYTPLH--IAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLS 691
Query: 375 YGGDVTLRTNGGVSALSFIVR 395
+ L G++ L + +
Sbjct: 692 KQANGNLGNKSGLTPLHLVAQ 712
Score = 151 bits (367), Expect = 7e-36
Identities = 106/289 (36%), Positives = 142/289 (49%), Gaps = 7/289 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P+ G T LH++C ++LLL GA + D+ TE+ TPLH A+
Sbjct: 392 LLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGA---SIDAVTESGLTPLHVASF 448
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
L VK L+ GA N + + +PLH A + EV K LL+ A + +TP
Sbjct: 449 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTP 508
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AA +G + KLLL A+ A G T LH+AA +GH E LL+ A
Sbjct: 509 LHCAARIGHTNMVKLLLENNANPNLATTAGH-TPLHIAAREGHVETVLALLEKEASQACM 567
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLH+A + V E+L++R A A +G TPLH A+ DI +LLL
Sbjct: 568 TKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH--NNLDIVKLLLP 625
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G P++ GYTPLHIAA LL YGG + GV+ L
Sbjct: 626 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 674
Score = 147 bits (355), Expect = 2e-34
Identities = 102/297 (34%), Positives = 144/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G I++ LL G + T LH + G ++LLDHGA + T+
Sbjct: 285 GNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGA---PIQAKTKNGL 341
Query: 155 TPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
+P+H AA L CV++L+ + A+++ L +PLH A V K LL+ GA P++
Sbjct: 342 SPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNS 401
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPLH+A +LLL GA + A G T LH+A+ GH + LL
Sbjct: 402 RALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESG-LTPLHVASFMGHLPIVKNLLQ 460
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
GA + N + +TPLH+A A EV + L+ A V AK D +TPLH A G
Sbjct: 461 RGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIG--HT 518
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
++ +LLL A+PN A G+TPLHIAA VL LL+ T G + L
Sbjct: 519 NMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPL 575
Score = 147 bits (355), Expect = 2e-34
Identities = 105/307 (34%), Positives = 144/307 (46%), Gaps = 7/307 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ + D++ T LH++ G K+LLD GA PN S TPLH A
Sbjct: 359 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPN---SRALNGFTPLHIACK 415
Query: 163 AKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ +++L+ GA ++A S +PLH A +VK LL+ GA P+ V ETP
Sbjct: 416 KNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETP 475
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G K LL A V A + T LH AA GH +LLL++ A+ +
Sbjct: 476 LHMAARAGHTEVAKYLLQNKAKVNAKAKDDQ-TPLHCAARIGHTNMVKLLLENNANPNLA 534
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A +E V L+++ A G TPLH A G +A LLL
Sbjct: 535 TTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGK--VRVAELLLE 592
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
A PNAA G TPLH+A + V LLL GG G + L ++ +
Sbjct: 593 RDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEV 652
Query: 402 PRYLCKF 408
R L ++
Sbjct: 653 ARSLLQY 659
Score = 143 bits (346), Expect = 2e-33
Identities = 91/245 (37%), Positives = 128/245 (52%), Gaps = 7/245 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G T LH++ G +LLL+ AHPN ++ + TPLH A +L VK+L+ G
Sbjct: 571 GFTPLHVAAKYGKVRVAELLLERDAHPN---AAGKNGLTPLHVAVHHNNLDIVKLLLPRG 627
Query: 177 ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
++ + +PLH A + EV + LL+ G + V TPLH+AA G A
Sbjct: 628 GSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVA 687
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL+ A+ G T LHL A++GH A +L+ HG +D G TPLH+A+
Sbjct: 688 LLLSKQANGNLGNKSG-LTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHY 746
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
++++V+ L+ ADV AK G +PLH A +G DI LLL GA PN + G T
Sbjct: 747 GNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQG--HTDIVTLLLKNGASPNEVSSDGTT 804
Query: 356 PLHIA 360
PL IA
Sbjct: 805 PLAIA 809
Score = 140 bits (339), Expect = 2e-32
Identities = 105/312 (33%), Positives = 147/312 (47%), Gaps = 7/312 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T + A +G + ++ LL+ +P+ AG T LH++ G E V LL+ A
Sbjct: 506 QTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEKEA--- 562
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T+ TPLH AA + ++L+ A NA G + +PLH AV + ++VK
Sbjct: 563 SQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKL 622
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL G P +P TPLH+AA + LL G A G T LHLAA++G
Sbjct: 623 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQG-VTPLHLAAQEG 681
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
HAE LLL A+ + N G TPLHL + V ++L+ V A G TPLH
Sbjct: 682 HAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLH 741
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G + + LL AD NA GY+PLH AA + V LLL G +
Sbjct: 742 VASHYGN--IKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS 799
Query: 384 NGGVSALSFIVR 395
+ G + L+ R
Sbjct: 800 SDGTTPLAIAKR 811
Score = 125 bits (302), Expect = 5e-28
Identities = 97/288 (33%), Positives = 136/288 (47%), Gaps = 11/288 (3%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K V+ DD +T LH + +G VKLLL++ A+PN +T TPLH AA
Sbjct: 495 KAKVNAKAKDD--QTPLHCAARIGHTNMVKLLLENNANPNL---ATTAGHTPLHIAAREG 549
Query: 165 SLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
+ V L+ A A ++ + +PLH A V + LLE A P+ TPL
Sbjct: 550 HVETVLALLEKEAS-QACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL 608
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
HVA + KLLL G + G T LH+AA+ E AR LL +G + +
Sbjct: 609 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGY-TPLHIAAKQNQVEVARSLLQYGGSANAES 667
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
+G TPLHLA E+V +L+ + A+ + G TPLH +V +A +L+
Sbjct: 668 VQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLH--LVAQEGHVPVADVLIKH 725
Query: 343 GADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G +A GYTPLH+A+ V LL + DV +T G S L
Sbjct: 726 GVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPL 773
Score = 124 bits (300), Expect = 9e-28
Identities = 91/284 (32%), Positives = 141/284 (49%), Gaps = 15/284 (5%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
++ +LL + + G T LH++ L G +E V+ L+++GA+ N + ++ TPL+
Sbjct: 95 MVVELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVN---AQSQKGFTPLY 151
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
AA L VK L+ +GA+ N D +PL A+ VV L+ G T
Sbjct: 152 MAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG----TKGKV 207
Query: 218 TETPLHVAASLGSASCTKLLL--NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
LH+AA +LL + DV + G T LH+AA + A+LLL+ G
Sbjct: 208 RLPALHIAARNDDTRTAAVLLQNDPNPDVLSKTG---FTPLHIAAHYENLNVAQLLLNRG 264
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI 335
A +++ G TPLH+A+ ++ +V +L+DR A + K D TPLH A G I
Sbjct: 265 ASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNG--HVRI 322
Query: 336 ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ +LL GA A G +P+H+AA + CV LLL Y ++
Sbjct: 323 SEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEI 366
Score = 121 bits (291), Expect = 1e-26
Identities = 86/260 (33%), Positives = 128/260 (49%), Gaps = 7/260 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ +PD L G T LH++ + +LLL+ GA N + + TPLH A+
Sbjct: 227 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNF---TPQNGITPLHIASR 283
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ V++L+ GA + D +PLH A + + + LL+ GA +P
Sbjct: 284 RGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSP 343
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H+AA C +LLL A++ + T LH+AA GH A++LLD GA +
Sbjct: 344 IHMAAQGDHLDCVRLLLQYDAEIDD-ITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 402
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLH+A + V+E+L+ A + A G TPLH A G I + LL
Sbjct: 403 ALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMG--HLPIVKNLLQ 460
Query: 342 AGADPNAADNFGYTPLHIAA 361
GA PN ++ TPLH+AA
Sbjct: 461 RGASPNVSNVKVETPLHMAA 480
Score = 119 bits (287), Expect = 3e-26
Identities = 90/290 (31%), Positives = 138/290 (47%), Gaps = 13/290 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + + G T L ++ G E V L+++G + + + LH AA
Sbjct: 165 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINYG-------TKGKVRLPALHIAAR 217
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTET 220
VL+ + + + + +PLH A + V + LL GA + TPQ T
Sbjct: 218 NDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGI-T 276
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+A+ G+ +LLL+ GA + + T LH AA +GH + +LLDHGA I
Sbjct: 277 PLHIASRRGNVIMVRLLLDRGAQIETKT-KDELTPLHCAARNGHVRISEILLDHGAPIQA 335
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G +P+H+A L+ V +L+ A++ D TPLH A G +A++LL
Sbjct: 336 KTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHR--VAKVLL 393
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA PN+ G+TPLHIA + LLL G + T G++ L
Sbjct: 394 DKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPL 443
Score = 118 bits (285), Expect = 6e-26
Identities = 98/311 (31%), Positives = 141/311 (45%), Gaps = 9/311 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G+ ++ +L+ G + + G T L+++ E VK LL++GA+ N
Sbjct: 115 TALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNV 174
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+TE TPL A V LI +G L LH A +D LL
Sbjct: 175 ---ATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLP---ALHIAARNDDTRTAAVLL 228
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ PD TPLH+AA + + +LLLN GA V G T LH+A+ G+
Sbjct: 229 QNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNG-ITPLHIASRRGNV 287
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
RLLLD GA I+ TPLH A + + E+L+D A ++AK +G +P+H A
Sbjct: 288 IMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMA 347
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
+G D RLLL A+ + TPLH+AA +LLD G R
Sbjct: 348 -AQGDHL-DCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALN 405
Query: 386 GVSALSFIVRR 396
G + L ++
Sbjct: 406 GFTPLHIACKK 416
Score = 84.2 bits (199), Expect = 2e-15
Identities = 65/203 (32%), Positives = 90/203 (44%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G P G T LH++ E + LL +G N + + TPLH AA
Sbjct: 623 LLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSAN---AESVQGVTPLHLAAQ 679
Query: 163 AKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V +L++ A+ N G S +PLH V L++ G D TP
Sbjct: 680 EGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTP 739
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA+ G+ K LL ADV A G + LH AA+ GH + LLL +GA +
Sbjct: 740 LHVASHYGNIKLVKFLLQHQADVNAKTKLGYSP-LHQAAQQGHTDIVTLLLKNGASPNEV 798
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G TPL +A + V ++L
Sbjct: 799 SSDGTTPLAIAKRLGYISVTDVL 821
Score = 80.6 bits (190), Expect = 2e-14
Identities = 72/236 (30%), Positives = 107/236 (45%), Gaps = 12/236 (5%)
Query: 173 IAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ +G D+N + + LH A ++V ELL +T T LH+AA G
Sbjct: 67 LRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILETTTKKGNTALHIAALAGQD 126
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
+ L+N GA+V A G T L++AA++ H E + LL++GA+ + G TPL +
Sbjct: 127 EVVRELVNYGANVNAQSQKG-FTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAV 185
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI--ARLLLSAGADPNAA 349
A VV L++ + R P A+ AR D A +LL +P+
Sbjct: 186 ALQQGHENVVAHLINYGTKGKV-----RLP---ALHIAARNDDTRTAAVLLQNDPNPDVL 237
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
G+TPLHIAA E LLL+ G V G++ L RR ++ R L
Sbjct: 238 SKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLL 293
Score = 65.7 bits (153), Expect = 6e-10
Identities = 53/164 (32%), Positives = 78/164 (47%), Gaps = 5/164 (3%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
++ AE G+ T + A G + ++ LL + + + +G T LHL G
Sbjct: 662 SANAESVQGV-TPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVAD 720
Query: 135 LLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLS-DRSPLHYAV 193
+L+ HG D++T TPLH A+ ++ VK L+ H ADVNA SPLH A
Sbjct: 721 VLIKHGVMV---DATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAA 777
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
++V LL+ GA P+ TPL +A LG S T +L
Sbjct: 778 QQGHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVL 821
Score = 59.3 bits (137), Expect = 5e-08
Identities = 43/156 (27%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
AT+ AA G+ + A L +G I+ N G LHLA+ +++V L+ + +
Sbjct: 48 ATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHKEIILE 107
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
G T LH A + G ++ R L++ GA+ NA G+TPL++AA V L
Sbjct: 108 TTTKKGNTALHIAALAGQD--EVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 165
Query: 373 LDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKF 408
L+ G + + T G + L+ +++ + + +L +
Sbjct: 166 LENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 201
>Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein.
Length = 3925
Score = 151 bits (366), Expect = 9e-36
Identities = 103/301 (34%), Positives = 154/301 (51%), Gaps = 7/301 (2%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC + ++ L+K G + ++G T +H++ +G V LLL +GA P+ +
Sbjct: 405 ACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRG 464
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
E T LH AA A + V+ L+ +GA V+A +++PLH A E+V+ LL+ A
Sbjct: 465 E---TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 521
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
PD TPLH++A G +LL AGA A G T LH+AA+ G + A+
Sbjct: 522 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKG-FTPLHVAAKYGSLDVAK 580
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL A D G TPLH+A + +V +L+++ A A +G TPLH I
Sbjct: 581 LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLH--IAAK 638
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
IA LL+ GA+ N G TPLH+A+ + V LLLD G ++ + T G+++
Sbjct: 639 KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTS 698
Query: 390 L 390
L
Sbjct: 699 L 699
Score = 149 bits (361), Expect = 4e-35
Identities = 110/312 (35%), Positives = 147/312 (47%), Gaps = 7/312 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T + A LGK+ ++ LL+ PD G T LH+S G + +LL+ GA +
Sbjct: 498 QTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS 557
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
+T+ TPLH AA SL K+L+ A + AG + +PLH A D +V
Sbjct: 558 L---ATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALL 614
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LLE GA P TPLH+AA LLN GA+ G T LHLA+++G
Sbjct: 615 LLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQG-VTPLHLASQEG 673
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + LLLD GA+I G T LHLA + V ++L AD A G TPL
Sbjct: 674 HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI 733
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G + LL GA+ NA GYTPLH AA + + +LL +G T
Sbjct: 734 VACHYG--NVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATT 791
Query: 384 NGGVSALSFIVR 395
G +AL+ R
Sbjct: 792 ANGNTALAIAKR 803
Score = 146 bits (354), Expect = 3e-34
Identities = 106/306 (34%), Positives = 154/306 (50%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + LL +P+ G T LH++C + ++LL+ +GA +
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGA---S 423
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
+ TE+ TP+H AA L V +L+ +GA + + + LH A + EVV+ L
Sbjct: 424 IQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 483
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L GA D +TPLH+A+ LG +LLL A AA G T LH++A +G
Sbjct: 484 LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNG-YTPLHISAREGQ 542
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A +LL+ GA +G TPLH+A SL+V ++L+ R A + +G TPLH
Sbjct: 543 VDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHV 602
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A + +A LLL GA P+A GYTPLHIAA LL+YG + + T
Sbjct: 603 AAHYDNQ--KVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTK 660
Query: 385 GGVSAL 390
GV+ L
Sbjct: 661 QGVTPL 666
Score = 140 bits (338), Expect = 2e-32
Identities = 94/279 (33%), Positives = 134/279 (48%), Gaps = 7/279 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G KLLLD A+PN + TPLH A + +++L+ +GA
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPN---ARALNGFTPLHIACKKNRIKVMELLVKYGAS 423
Query: 179 VNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ A S +P+H A +V LL+ GA PD + ET LH+AA G + L
Sbjct: 424 IQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 483
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L GA V A + T LH+A+ G E +LLL H AH D G TPLH++
Sbjct: 484 LRNGALVDARARE-EQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQ 542
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
++V +L++ A G TPLH A G+ D+A+LLL A ++A G TPL
Sbjct: 543 VDVASVLLEAGAAHSLATKKGFTPLHVAAKYGS--LDVAKLLLQRRAAADSAGKNGLTPL 600
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
H+AA + LLLL+ G G + L ++
Sbjct: 601 HVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK 639
Score = 139 bits (336), Expect = 4e-32
Identities = 107/324 (33%), Positives = 153/324 (47%), Gaps = 12/324 (3%)
Query: 68 YDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLV 127
Y +IQ +E+ GL T I A ++G ++ LL+ G PD + G T LH++
Sbjct: 420 YGASIQAITES----GL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARA 474
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-R 186
G E V+ LL +GA D+ + TPLH A+ V++L+ H A +A ++
Sbjct: 475 GQVEVVRCLLRNGA---LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 531
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH + +V LLEAGA TPLHVAA GS KLLL A +
Sbjct: 532 TPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADS 591
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
A G T LH+AA + + A LLL+ GA G TPLH+A +++ L++
Sbjct: 592 A-GKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
A+ G TPLH A G D+ LLL GA+ + + G T LH+AA +
Sbjct: 651 YGAETNIVTKQGVTPLHLASQEG--HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKV 708
Query: 367 ACVLLLLDYGGDVTLRTNGGVSAL 390
+L +G D T G + L
Sbjct: 709 NVADILTKHGADQDAHTKLGYTPL 732
Score = 132 bits (319), Expect = 4e-30
Identities = 111/334 (33%), Positives = 160/334 (47%), Gaps = 30/334 (8%)
Query: 66 GNYDETIQFASEAEGGFGLRT-------AILWACWLGKSILLFKLLKMGVDPDELDDAGR 118
GN D+ +++ +GG + T A+ A G L+ +LL G D G
Sbjct: 42 GNLDKVVEYL---KGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGN 98
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ L G E VK+L+ GA+ N + ++ TPL+ AA + VK L+ +GA+
Sbjct: 99 TALHIASLAGQAEVVKVLVKEGANIN---AQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ D +PL A+ + V LLE DT LH+AA LL
Sbjct: 156 QSTATEDGFTPLAVALQQGHNQAVAILLEN----DTKGKVRLPALHIAARKDDTKSAALL 211
Query: 238 L--NAGADVRAAMGPGKATA-----LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
L + ADV++ M + T LH+AA G+ A LLL+ GA +D+ G TPLH
Sbjct: 212 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 271
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
+A+ + +V++L+DR + AK DG TPLH A G + LLL GA A
Sbjct: 272 VASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD--QVVELLLERGAPLLART 329
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGG---DVTL 381
G +PLH+AA + CV LL + DVTL
Sbjct: 330 KNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTL 363
Score = 127 bits (306), Expect = 2e-28
Identities = 91/246 (36%), Positives = 125/246 (50%), Gaps = 7/246 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G + LH++ ECVK LL H A D T T LH AA K+L+
Sbjct: 332 GLSPLHMAAQGDHVECVKHLLQHKAPV---DDVTLDYLTALHVAAHCGHYRVTKLLLDKR 388
Query: 177 ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
A+ NA L+ +PLH A + +V++ L++ GA TP+HVAA +G +
Sbjct: 389 ANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVL 448
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL GA G+ TALH+AA G E R LL +GA +D QTPLH+A+
Sbjct: 449 LLLQNGASPDVTNIRGE-TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRL 507
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
E+V++L+ A A +G TPLH + G D+A +LL AGA + A G+T
Sbjct: 508 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREG--QVDVASVLLEAGAAHSLATKKGFT 565
Query: 356 PLHIAA 361
PLH+AA
Sbjct: 566 PLHVAA 571
Score = 124 bits (299), Expect = 1e-27
Identities = 106/313 (33%), Positives = 148/313 (47%), Gaps = 19/313 (6%)
Query: 87 AILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTW 146
+ L A G + + LK G+D + + G LHL+ G V+ LL G ++
Sbjct: 34 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRG---SSV 90
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELL 205
DS+T+ T LH A+ A VKVL+ GA++NA + +PL+ A + +VVK LL
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLL 150
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
E GA T TPL VA G +LL G + ALH+AA
Sbjct: 151 ENGANQSTATEDGFTPLAVALQQGHNQAVAILLE-----NDTKGKVRLPALHIAARKDDT 205
Query: 266 ECARLLL--DHGAH------IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
+ A LLL DH A ++ G TPLH+A ++ V +L++R A V +
Sbjct: 206 KSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN 265
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G TPLH A RG ++ +LLL G +A G TPLH AA + V LLL+ G
Sbjct: 266 GITPLHVASKRG--NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGA 323
Query: 378 DVTLRTNGGVSAL 390
+ RT G+S L
Sbjct: 324 PLLARTKNGLSPL 336
Score = 113 bits (271), Expect = 3e-24
Identities = 93/297 (31%), Positives = 133/297 (44%), Gaps = 19/297 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + G T L ++ G + V +LL++ D+ + + LH AA
Sbjct: 149 LLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEN-------DTKGKVRLPALHIAAR 201
Query: 163 AKSLACVKVLIA--HGADVNAGL-------SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
+L+ H ADV + + S +PLH A V LL GA D
Sbjct: 202 KDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 261
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPLHVA+ G+ + KLLL+ G + A G T LH AA GH + LLL+
Sbjct: 262 TARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDG-LTPLHCAARSGHDQVVELLLE 320
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
GA + G +PLH+A +E V+ L+ A V D T LH A G
Sbjct: 321 RGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYR- 379
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ +LLL A+PNA G+TPLHIA + LL+ YG + T G++ +
Sbjct: 380 -VTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435
Score = 89.4 bits (212), Expect = 4e-17
Identities = 71/231 (30%), Positives = 101/231 (43%), Gaps = 6/231 (2%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
A+++ G GL + A + + + L LL+ G P G T LH++ +
Sbjct: 588 AADSAGKNGLTPLHVAAHYDNQKVALL-LLEKGASPHATAKNGYTPLHIAAKKNQMQIAS 646
Query: 135 LLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAV 193
LL++GA N T+ TPLH A+ V +L+ GA+++ S + LH A
Sbjct: 647 TLLNYGAETNI---VTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAA 703
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKA 253
D V L + GA D TPL VA G+ LL GA+V A G
Sbjct: 704 QEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGY- 762
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
T LH AA+ GH +LL HGA + G T L +A + VV+ L
Sbjct: 763 TPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
Score = 57.6 bits (133), Expect = 2e-07
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+ + L G I+ N G LHLA + +V+ L+ R + V + G
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 97
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
T LH A + G ++ ++L+ GA+ NA G+TPL++AA V LL+ G +
Sbjct: 98 NTALHIASLAG--QAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
Query: 379 VTLRTNGGVSALSFIVRR 396
+ T G + L+ +++
Sbjct: 156 QSTATEDGFTPLAVALQQ 173
>X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein.
Length = 1872
Score = 151 bits (366), Expect = 9e-36
Identities = 103/301 (34%), Positives = 154/301 (51%), Gaps = 7/301 (2%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC + ++ L+K G + ++G T +H++ +G V LLL +GA P+ +
Sbjct: 405 ACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRG 464
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
E T LH AA A + V+ L+ +GA V+A +++PLH A E+V+ LL+ A
Sbjct: 465 E---TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 521
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
PD TPLH++A G +LL AGA A G T LH+AA+ G + A+
Sbjct: 522 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKG-FTPLHVAAKYGSLDVAK 580
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL A D G TPLH+A + +V +L+++ A A +G TPLH I
Sbjct: 581 LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLH--IAAK 638
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
IA LL+ GA+ N G TPLH+A+ + V LLLD G ++ + T G+++
Sbjct: 639 KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTS 698
Query: 390 L 390
L
Sbjct: 699 L 699
Score = 149 bits (361), Expect = 4e-35
Identities = 110/312 (35%), Positives = 147/312 (47%), Gaps = 7/312 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T + A LGK+ ++ LL+ PD G T LH+S G + +LL+ GA +
Sbjct: 498 QTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS 557
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
+T+ TPLH AA SL K+L+ A + AG + +PLH A D +V
Sbjct: 558 L---ATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALL 614
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LLE GA P TPLH+AA LLN GA+ G T LHLA+++G
Sbjct: 615 LLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQG-VTPLHLASQEG 673
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + LLLD GA+I G T LHLA + V ++L AD A G TPL
Sbjct: 674 HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI 733
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G + LL GA+ NA GYTPLH AA + + +LL +G T
Sbjct: 734 VACHYG--NVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATT 791
Query: 384 NGGVSALSFIVR 395
G +AL+ R
Sbjct: 792 ANGNTALAIAKR 803
Score = 146 bits (354), Expect = 3e-34
Identities = 106/306 (34%), Positives = 154/306 (50%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + LL +P+ G T LH++C + ++LL+ +GA +
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGA---S 423
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
+ TE+ TP+H AA L V +L+ +GA + + + LH A + EVV+ L
Sbjct: 424 IQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 483
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L GA D +TPLH+A+ LG +LLL A AA G T LH++A +G
Sbjct: 484 LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNG-YTPLHISAREGQ 542
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A +LL+ GA +G TPLH+A SL+V ++L+ R A + +G TPLH
Sbjct: 543 VDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHV 602
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A + +A LLL GA P+A GYTPLHIAA LL+YG + + T
Sbjct: 603 AAHYDNQ--KVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTK 660
Query: 385 GGVSAL 390
GV+ L
Sbjct: 661 QGVTPL 666
Score = 140 bits (338), Expect = 2e-32
Identities = 94/279 (33%), Positives = 134/279 (48%), Gaps = 7/279 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G KLLLD A+PN + TPLH A + +++L+ +GA
Sbjct: 367 TALHVAAHCGHYRVTKLLLDKRANPN---ARALNGFTPLHIACKKNRIKVMELLVKYGAS 423
Query: 179 VNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ A S +P+H A +V LL+ GA PD + ET LH+AA G + L
Sbjct: 424 IQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 483
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L GA V A + T LH+A+ G E +LLL H AH D G TPLH++
Sbjct: 484 LRNGALVDARARE-EQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQ 542
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
++V +L++ A G TPLH A G+ D+A+LLL A ++A G TPL
Sbjct: 543 VDVASVLLEAGAAHSLATKKGFTPLHVAAKYGS--LDVAKLLLQRRAAADSAGKNGLTPL 600
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
H+AA + LLLL+ G G + L ++
Sbjct: 601 HVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK 639
Score = 139 bits (336), Expect = 4e-32
Identities = 107/324 (33%), Positives = 153/324 (47%), Gaps = 12/324 (3%)
Query: 68 YDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLV 127
Y +IQ +E+ GL T I A ++G ++ LL+ G PD + G T LH++
Sbjct: 420 YGASIQAITES----GL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARA 474
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-R 186
G E V+ LL +GA D+ + TPLH A+ V++L+ H A +A ++
Sbjct: 475 GQVEVVRCLLRNGA---LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 531
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH + +V LLEAGA TPLHVAA GS KLLL A +
Sbjct: 532 TPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADS 591
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
A G T LH+AA + + A LLL+ GA G TPLH+A +++ L++
Sbjct: 592 A-GKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 650
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
A+ G TPLH A G D+ LLL GA+ + + G T LH+AA +
Sbjct: 651 YGAETNIVTKQGVTPLHLASQEG--HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKV 708
Query: 367 ACVLLLLDYGGDVTLRTNGGVSAL 390
+L +G D T G + L
Sbjct: 709 NVADILTKHGADQDAHTKLGYTPL 732
Score = 132 bits (319), Expect = 4e-30
Identities = 111/334 (33%), Positives = 160/334 (47%), Gaps = 30/334 (8%)
Query: 66 GNYDETIQFASEAEGGFGLRT-------AILWACWLGKSILLFKLLKMGVDPDELDDAGR 118
GN D+ +++ +GG + T A+ A G L+ +LL G D G
Sbjct: 42 GNLDKVVEYL---KGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGN 98
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ L G E VK+L+ GA+ N + ++ TPL+ AA + VK L+ +GA+
Sbjct: 99 TALHIASLAGQAEVVKVLVKEGANIN---AQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ D +PL A+ + V LLE DT LH+AA LL
Sbjct: 156 QSTATEDGFTPLAVALQQGHNQAVAILLEN----DTKGKVRLPALHIAARKDDTKSAALL 211
Query: 238 L--NAGADVRAAMGPGKATA-----LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
L + ADV++ M + T LH+AA G+ A LLL+ GA +D+ G TPLH
Sbjct: 212 LQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 271
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
+A+ + +V++L+DR + AK DG TPLH A G + LLL GA A
Sbjct: 272 VASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD--QVVELLLERGAPLLART 329
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGG---DVTL 381
G +PLH+AA + CV LL + DVTL
Sbjct: 330 KNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTL 363
Score = 127 bits (306), Expect = 2e-28
Identities = 91/246 (36%), Positives = 125/246 (50%), Gaps = 7/246 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G + LH++ ECVK LL H A D T T LH AA K+L+
Sbjct: 332 GLSPLHMAAQGDHVECVKHLLQHKAPV---DDVTLDYLTALHVAAHCGHYRVTKLLLDKR 388
Query: 177 ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
A+ NA L+ +PLH A + +V++ L++ GA TP+HVAA +G +
Sbjct: 389 ANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVL 448
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL GA G+ TALH+AA G E R LL +GA +D QTPLH+A+
Sbjct: 449 LLLQNGASPDVTNIRGE-TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRL 507
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
E+V++L+ A A +G TPLH + G D+A +LL AGA + A G+T
Sbjct: 508 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREG--QVDVASVLLEAGAAHSLATKKGFT 565
Query: 356 PLHIAA 361
PLH+AA
Sbjct: 566 PLHVAA 571
Score = 124 bits (299), Expect = 1e-27
Identities = 106/313 (33%), Positives = 148/313 (47%), Gaps = 19/313 (6%)
Query: 87 AILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTW 146
+ L A G + + LK G+D + + G LHL+ G V+ LL G ++
Sbjct: 34 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRG---SSV 90
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELL 205
DS+T+ T LH A+ A VKVL+ GA++NA + +PL+ A + +VVK LL
Sbjct: 91 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLL 150
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
E GA T TPL VA G +LL G + ALH+AA
Sbjct: 151 ENGANQSTATEDGFTPLAVALQQGHNQAVAILLE-----NDTKGKVRLPALHIAARKDDT 205
Query: 266 ECARLLL--DHGAH------IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
+ A LLL DH A ++ G TPLH+A ++ V +L++R A V +
Sbjct: 206 KSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN 265
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G TPLH A RG ++ +LLL G +A G TPLH AA + V LLL+ G
Sbjct: 266 GITPLHVASKRG--NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGA 323
Query: 378 DVTLRTNGGVSAL 390
+ RT G+S L
Sbjct: 324 PLLARTKNGLSPL 336
Score = 113 bits (271), Expect = 3e-24
Identities = 93/297 (31%), Positives = 133/297 (44%), Gaps = 19/297 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + G T L ++ G + V +LL++ D+ + + LH AA
Sbjct: 149 LLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEN-------DTKGKVRLPALHIAAR 201
Query: 163 AKSLACVKVLIA--HGADVNAGL-------SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
+L+ H ADV + + S +PLH A V LL GA D
Sbjct: 202 KDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 261
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPLHVA+ G+ + KLLL+ G + A G T LH AA GH + LLL+
Sbjct: 262 TARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDG-LTPLHCAARSGHDQVVELLLE 320
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
GA + G +PLH+A +E V+ L+ A V D T LH A G
Sbjct: 321 RGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYR- 379
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ +LLL A+PNA G+TPLHIA + LL+ YG + T G++ +
Sbjct: 380 -VTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 435
Score = 89.4 bits (212), Expect = 4e-17
Identities = 71/231 (30%), Positives = 101/231 (43%), Gaps = 6/231 (2%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
A+++ G GL + A + + + L LL+ G P G T LH++ +
Sbjct: 588 AADSAGKNGLTPLHVAAHYDNQKVALL-LLEKGASPHATAKNGYTPLHIAAKKNQMQIAS 646
Query: 135 LLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAV 193
LL++GA N T+ TPLH A+ V +L+ GA+++ S + LH A
Sbjct: 647 TLLNYGAETNI---VTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAA 703
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKA 253
D V L + GA D TPL VA G+ LL GA+V A G
Sbjct: 704 QEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGY- 762
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
T LH AA+ GH +LL HGA + G T L +A + VV+ L
Sbjct: 763 TPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 813
Score = 57.6 bits (133), Expect = 2e-07
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+ + L G I+ N G LHLA + +V+ L+ R + V + G
Sbjct: 38 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 97
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
T LH A + G ++ ++L+ GA+ NA G+TPL++AA V LL+ G +
Sbjct: 98 NTALHIASLAG--QAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
Query: 379 VTLRTNGGVSALSFIVRR 396
+ T G + L+ +++
Sbjct: 156 QSTATEDGFTPLAVALQQ 173
>BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein
protein.
Length = 1863
Score = 151 bits (366), Expect = 9e-36
Identities = 103/301 (34%), Positives = 154/301 (51%), Gaps = 7/301 (2%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC + ++ L+K G + ++G T +H++ +G V LLL +GA P+ +
Sbjct: 384 ACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRG 443
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
E T LH AA A + V+ L+ +GA V+A +++PLH A E+V+ LL+ A
Sbjct: 444 E---TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMA 500
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
PD TPLH++A G +LL AGA A G T LH+AA+ G + A+
Sbjct: 501 HPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKG-FTPLHVAAKYGSLDVAK 559
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL A D G TPLH+A + +V +L+++ A A +G TPLH I
Sbjct: 560 LLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLH--IAAK 617
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
IA LL+ GA+ N G TPLH+A+ + V LLLD G ++ + T G+++
Sbjct: 618 KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTS 677
Query: 390 L 390
L
Sbjct: 678 L 678
Score = 149 bits (361), Expect = 4e-35
Identities = 110/312 (35%), Positives = 147/312 (47%), Gaps = 7/312 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T + A LGK+ ++ LL+ PD G T LH+S G + +LL+ GA +
Sbjct: 477 QTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHS 536
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
+T+ TPLH AA SL K+L+ A + AG + +PLH A D +V
Sbjct: 537 L---ATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALL 593
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LLE GA P TPLH+AA LLN GA+ G T LHLA+++G
Sbjct: 594 LLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQG-VTPLHLASQEG 652
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + LLLD GA+I G T LHLA + V ++L AD A G TPL
Sbjct: 653 HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLI 712
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G + LL GA+ NA GYTPLH AA + + +LL +G T
Sbjct: 713 VACHYG--NVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATT 770
Query: 384 NGGVSALSFIVR 395
G +AL+ R
Sbjct: 771 ANGNTALAIAKR 782
Score = 146 bits (354), Expect = 3e-34
Identities = 106/306 (34%), Positives = 154/306 (50%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + LL +P+ G T LH++C + ++LL+ +GA +
Sbjct: 346 TALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGA---S 402
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
+ TE+ TP+H AA L V +L+ +GA + + + LH A + EVV+ L
Sbjct: 403 IQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 462
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L GA D +TPLH+A+ LG +LLL A AA G T LH++A +G
Sbjct: 463 LRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNG-YTPLHISAREGQ 521
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ A +LL+ GA +G TPLH+A SL+V ++L+ R A + +G TPLH
Sbjct: 522 VDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHV 581
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A + +A LLL GA P+A GYTPLHIAA LL+YG + + T
Sbjct: 582 AAHYDNQ--KVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTK 639
Query: 385 GGVSAL 390
GV+ L
Sbjct: 640 QGVTPL 645
Score = 140 bits (338), Expect = 2e-32
Identities = 94/279 (33%), Positives = 134/279 (48%), Gaps = 7/279 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G KLLLD A+PN + TPLH A + +++L+ +GA
Sbjct: 346 TALHVAAHCGHYRVTKLLLDKRANPN---ARALNGFTPLHIACKKNRIKVMELLVKYGAS 402
Query: 179 VNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ A S +P+H A +V LL+ GA PD + ET LH+AA G + L
Sbjct: 403 IQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCL 462
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L GA V A + T LH+A+ G E +LLL H AH D G TPLH++
Sbjct: 463 LRNGALVDARARE-EQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQ 521
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
++V +L++ A G TPLH A G+ D+A+LLL A ++A G TPL
Sbjct: 522 VDVASVLLEAGAAHSLATKKGFTPLHVAAKYGS--LDVAKLLLQRRAAADSAGKNGLTPL 579
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
H+AA + LLLL+ G G + L ++
Sbjct: 580 HVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKK 618
Score = 139 bits (336), Expect = 4e-32
Identities = 107/324 (33%), Positives = 153/324 (47%), Gaps = 12/324 (3%)
Query: 68 YDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLV 127
Y +IQ +E+ GL T I A ++G ++ LL+ G PD + G T LH++
Sbjct: 399 YGASIQAITES----GL-TPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARA 453
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-R 186
G E V+ LL +GA D+ + TPLH A+ V++L+ H A +A ++
Sbjct: 454 GQVEVVRCLLRNGA---LVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGY 510
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH + +V LLEAGA TPLHVAA GS KLLL A +
Sbjct: 511 TPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADS 570
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
A G T LH+AA + + A LLL+ GA G TPLH+A +++ L++
Sbjct: 571 A-GKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLN 629
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
A+ G TPLH A G D+ LLL GA+ + + G T LH+AA +
Sbjct: 630 YGAETNIVTKQGVTPLHLASQEG--HTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKV 687
Query: 367 ACVLLLLDYGGDVTLRTNGGVSAL 390
+L +G D T G + L
Sbjct: 688 NVADILTKHGADQDAHTKLGYTPL 711
Score = 132 bits (318), Expect = 6e-30
Identities = 110/334 (32%), Positives = 160/334 (47%), Gaps = 30/334 (8%)
Query: 66 GNYDETIQFASEAEGGFGLRT-------AILWACWLGKSILLFKLLKMGVDPDELDDAGR 118
GN D+ +++ +GG + T A+ A G L+ +LL G D G
Sbjct: 21 GNLDKVVEYL---KGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGN 77
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ L G E VK+L+ GA+ N + ++ TPL+ AA + VK L+ +GA+
Sbjct: 78 TALHIASLAGQAEVVKVLVKEGANIN---AQSQNGFTPLYMAAQENHIDVVKYLLENGAN 134
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ D +PL A+ + V LLE DT LH+AA LL
Sbjct: 135 QSTATEDGFTPLAVALQQGHNQAVAILLEN----DTKGKVRLPALHIAARKDDTKSAALL 190
Query: 238 L--NAGADVRAAMGPGKATA-----LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
L + AD+++ M + T LH+AA G+ A LLL+ GA +D+ G TPLH
Sbjct: 191 LQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLH 250
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
+A+ + +V++L+DR + AK DG TPLH A G + LLL GA A
Sbjct: 251 VASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHD--QVVELLLERGAPLLART 308
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGG---DVTL 381
G +PLH+AA + CV LL + DVTL
Sbjct: 309 KNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTL 342
Score = 127 bits (306), Expect = 2e-28
Identities = 91/246 (36%), Positives = 125/246 (50%), Gaps = 7/246 (2%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G + LH++ ECVK LL H A D T T LH AA K+L+
Sbjct: 311 GLSPLHMAAQGDHVECVKHLLQHKAPV---DDVTLDYLTALHVAAHCGHYRVTKLLLDKR 367
Query: 177 ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
A+ NA L+ +PLH A + +V++ L++ GA TP+HVAA +G +
Sbjct: 368 ANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVL 427
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LLL GA G+ TALH+AA G E R LL +GA +D QTPLH+A+
Sbjct: 428 LLLQNGASPDVTNIRGE-TALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRL 486
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
E+V++L+ A A +G TPLH + G D+A +LL AGA + A G+T
Sbjct: 487 GKTEIVQLLLQHMAHPDAATTNGYTPLHISAREG--QVDVASVLLEAGAAHSLATKKGFT 544
Query: 356 PLHIAA 361
PLH+AA
Sbjct: 545 PLHVAA 550
Score = 124 bits (300), Expect = 9e-28
Identities = 107/313 (34%), Positives = 148/313 (47%), Gaps = 19/313 (6%)
Query: 87 AILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTW 146
+ L A G + + LK G+D + + G LHL+ G V+ LL G ++
Sbjct: 13 SFLRAARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRG---SSV 69
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELL 205
DS+T+ T LH A+ A VKVL+ GA++NA + +PL+ A + +VVK LL
Sbjct: 70 DSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLL 129
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
E GA T TPL VA G +LL G + ALH+AA
Sbjct: 130 ENGANQSTATEDGFTPLAVALQQGHNQAVAILLE-----NDTKGKVRLPALHIAARKDDT 184
Query: 266 ECARLLL--DHGAHI------DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
+ A LLL DH A I + G TPLH+A ++ V +L++R A V +
Sbjct: 185 KSAALLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARN 244
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G TPLH A RG ++ +LLL G +A G TPLH AA + V LLL+ G
Sbjct: 245 GITPLHVASKRG--NTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGA 302
Query: 378 DVTLRTNGGVSAL 390
+ RT G+S L
Sbjct: 303 PLLARTKNGLSPL 315
Score = 112 bits (270), Expect = 4e-24
Identities = 92/297 (30%), Positives = 133/297 (44%), Gaps = 19/297 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + G T L ++ G + V +LL++ D+ + + LH AA
Sbjct: 128 LLENGANQSTATEDGFTPLAVALQQGHNQAVAILLEN-------DTKGKVRLPALHIAAR 180
Query: 163 AKSLACVKVLIA--HGADVNAGL-------SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
+L+ H AD+ + + S +PLH A V LL GA D
Sbjct: 181 KDDTKSAALLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDF 240
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPLHVA+ G+ + KLLL+ G + A G T LH AA GH + LLL+
Sbjct: 241 TARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDG-LTPLHCAARSGHDQVVELLLE 299
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
GA + G +PLH+A +E V+ L+ A V D T LH A G
Sbjct: 300 RGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYR- 358
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ +LLL A+PNA G+TPLHIA + LL+ YG + T G++ +
Sbjct: 359 -VTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPI 414
Score = 89.4 bits (212), Expect = 4e-17
Identities = 71/231 (30%), Positives = 101/231 (43%), Gaps = 6/231 (2%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
A+++ G GL + A + + + L LL+ G P G T LH++ +
Sbjct: 567 AADSAGKNGLTPLHVAAHYDNQKVALL-LLEKGASPHATAKNGYTPLHIAAKKNQMQIAS 625
Query: 135 LLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAV 193
LL++GA N T+ TPLH A+ V +L+ GA+++ S + LH A
Sbjct: 626 TLLNYGAETNI---VTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAA 682
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKA 253
D V L + GA D TPL VA G+ LL GA+V A G
Sbjct: 683 QEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGY- 741
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
T LH AA+ GH +LL HGA + G T L +A + VV+ L
Sbjct: 742 TPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTL 792
Score = 57.6 bits (133), Expect = 2e-07
Identities = 40/138 (28%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+ + L G I+ N G LHLA + +V+ L+ R + V + G
Sbjct: 17 AARAGNLDKVVEYLKGGIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKG 76
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
T LH A + G ++ ++L+ GA+ NA G+TPL++AA V LL+ G +
Sbjct: 77 NTALHIASLAG--QAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 134
Query: 379 VTLRTNGGVSALSFIVRR 396
+ T G + L+ +++
Sbjct: 135 QSTATEDGFTPLAVALQQ 152
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 151 bits (365), Expect = 1e-35
Identities = 101/285 (35%), Positives = 141/285 (49%), Gaps = 7/285 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + +D+ G LH + G + +LLLDHGA D+ TPLH AA
Sbjct: 414 LLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGA---CVDAQEREGWTPLHLAAQ 470
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++L++ AD N ++ ++PLH A +VK L GA D Q TP
Sbjct: 471 NNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTP 530
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+A G + LL +GA V A+ LH AA G ++LL +GA ++ P
Sbjct: 531 LHLAVERGKVRAIQHLLKSGA-VPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP 589
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLHLA LE++ +L + A++ A A TPLH A G A + LL
Sbjct: 590 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEA--VVSALLQ 647
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
GADPNAA+ G+TPLH+A V+ LL++ +V R G
Sbjct: 648 CGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVG 692
Score = 133 bits (322), Expect = 2e-30
Identities = 99/294 (33%), Positives = 143/294 (48%), Gaps = 7/294 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + G T LHL+ E +LL+ A PN ++ +T PLH AA
Sbjct: 447 LLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKT---PLHVAAY 503
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ VK+L + GA+++A + R+PLH AV ++ LL++GA PD P
Sbjct: 504 FGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGP 563
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AA+ G K+LL GA + G T LHLAA GH E LL + A++
Sbjct: 564 LHTAAARGKYLICKMLLRYGASLELPTHQGW-TPLHLAAYKGHLEIIHLLAESHANMGAL 622
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
TPLHLA VV L+ AD A + G TPLH A+ R I LL
Sbjct: 623 GAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVIN--LLE 680
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
A+ +A + G+TP H+AAL +A + +L++ G + ++ + L +R
Sbjct: 681 HHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALR 734
Score = 126 bits (304), Expect = 3e-28
Identities = 92/257 (35%), Positives = 123/257 (47%), Gaps = 7/257 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH GS E V+LLL AH D T + TPL AA + +L+AHGAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLL---AHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD 420
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
N D +PLH+A + + LL+ GAC D + TPLH+AA + +LL
Sbjct: 421 ANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLL 480
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
++ AD GK T LH+AA GH +LL GA +D +TPLHLA
Sbjct: 481 VSRQADPNLHEAEGK-TPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGK 539
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ ++ L+ A A D G PLH A RG I ++LL GA + G+TPL
Sbjct: 540 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYL--ICKMLLRYGASLELPTHQGWTPL 597
Query: 358 HIAALNEFSACVLLLLD 374
H+AA + LL +
Sbjct: 598 HLAAYKGHLEIIHLLAE 614
Score = 124 bits (298), Expect = 2e-27
Identities = 89/242 (36%), Positives = 124/242 (51%), Gaps = 6/242 (2%)
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGA 209
E K TPLH + S+ V++L+AH DV+ S +PL A P++ LL GA
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGA 419
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ PLH AA G +LLL+ GA V A G T LHLAA++ AR
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGW-TPLHLAAQNNFENVAR 478
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ A + G+TPLH+A + +V++L + A++ A+ + RTPLH A+ RG
Sbjct: 479 LLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERG 538
Query: 330 -ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVS 388
RA + LL +GA P+A D GY PLH AA +LL YG + L T+ G +
Sbjct: 539 KVRAI---QHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWT 595
Query: 389 AL 390
L
Sbjct: 596 PL 597
Score = 122 bits (293), Expect = 6e-27
Identities = 112/360 (31%), Positives = 156/360 (43%), Gaps = 18/360 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL VD D +G T L ++ + LLL HGA N D E PLH AA
Sbjct: 381 LLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVD---EDGWAPLHFAAQ 437
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++L+ HGA V+A + +PLH A ++ V + L+ A P+ + +TP
Sbjct: 438 NGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTP 497
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVAA G S KLL + GA++ A T LHLA E G + LL GA D
Sbjct: 498 LHVAAYFGHVSLVKLLTSQGAELDAQQR-NLRTPLHLAVERGKVRAIQHLLKSGAVPDAL 556
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ G PLH A + +ML+ A + G TPLH A +G +I LL
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGH--LEIIHLLAE 614
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
+ A+ A +TPLH+AA + A V LL G D G + L V+R
Sbjct: 615 SHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQR----- 669
Query: 402 PRYLCKFDDAVHVSEHELGDVDCELTIDFRPLVPCLTRGEAELLLAFVEI-PYWDVDNGV 460
F +++ EH +V + + P +G +L VE DV +GV
Sbjct: 670 ----STFLSVINLLEHH-ANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGV 724
Score = 114 bits (275), Expect = 9e-25
Identities = 93/285 (32%), Positives = 132/285 (46%), Gaps = 9/285 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+ DP+ + G+T LH++ G VKLL GA D+ TPLH A
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAE---LDAQQRNLRTPLHLAVE 536
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ ++ L+ GA +A S PLH A + K LL GA + P TP
Sbjct: 537 RGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTP 596
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G LL + A++ A+G T LHLAA G LL GA +
Sbjct: 597 LHLAAYKGHLEIIHLLAESHANM-GALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAA 655
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLHLA + V L++ A+V A++ G TP H A ++G A I ++L+
Sbjct: 656 EQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTA--ILKVLVE 713
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
AGA + D TPL + AL ++ L+ G + ++ T GG
Sbjct: 714 AGAQLDVQDGVSCTPLQL-ALRSRKQGIMSFLE-GKEPSVATLGG 756
Score = 103 bits (248), Expect = 2e-21
Identities = 78/232 (33%), Positives = 104/232 (44%), Gaps = 3/232 (1%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH+ V + E V+ LL D TPL +AA LLL GAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
G A LH AA++G ARLLLDHGA +D G TPLHLA V +LV
Sbjct: 424 VDEDGWAP-LHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVS 482
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
R AD +A+G+TPLH A G + +LL S GA+ +A TPLH+A
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFG--HVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKV 540
Query: 367 ACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+ LL G G L R +I + L ++ ++ + H+
Sbjct: 541 RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQ 592
Score = 90.2 bits (214), Expect = 2e-17
Identities = 73/222 (32%), Positives = 104/222 (46%), Gaps = 5/222 (2%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
LRT + A GK + LLK G PD LD +G LH + G K+LL +GA
Sbjct: 527 LRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGA-- 584
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVK 202
+ + T TPLH AA L + +L A++ A G + +PLH A VV
Sbjct: 585 -SLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVS 643
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL+ GA P+ + TPLH+A + LL A+V A G T HLAA
Sbjct: 644 ALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVG-WTPAHLAALK 702
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
G+ ++L++ GA +D + TPL LA ++ ++ L
Sbjct: 703 GNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL 744
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 151 bits (365), Expect = 1e-35
Identities = 101/285 (35%), Positives = 141/285 (49%), Gaps = 7/285 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + +D+ G LH + G + +LLLDHGA D+ TPLH AA
Sbjct: 414 LLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGA---CVDAQEREGWTPLHLAAQ 470
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++L++ AD N ++ ++PLH A +VK L GA D Q TP
Sbjct: 471 NNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTP 530
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+A G + LL +GA V A+ LH AA G ++LL +GA ++ P
Sbjct: 531 LHLAVERGKVRAIQHLLKSGA-VPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP 589
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLHLA LE++ +L + A++ A A TPLH A G A + LL
Sbjct: 590 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEA--VVSALLQ 647
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
GADPNAA+ G+TPLH+A V+ LL++ +V R G
Sbjct: 648 CGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVG 692
Score = 133 bits (322), Expect = 2e-30
Identities = 99/294 (33%), Positives = 143/294 (48%), Gaps = 7/294 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + G T LHL+ E +LL+ A PN ++ +T PLH AA
Sbjct: 447 LLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKT---PLHVAAY 503
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ VK+L + GA+++A + R+PLH AV ++ LL++GA PD P
Sbjct: 504 FGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGP 563
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AA+ G K+LL GA + G T LHLAA GH E LL + A++
Sbjct: 564 LHTAAARGKYLICKMLLRYGASLELPTHQGW-TPLHLAAYKGHLEIIHLLAESHANMGAL 622
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
TPLHLA VV L+ AD A + G TPLH A+ R I LL
Sbjct: 623 GAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVIN--LLE 680
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
A+ +A + G+TP H+AAL +A + +L++ G + ++ + L +R
Sbjct: 681 HHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALR 734
Score = 126 bits (304), Expect = 3e-28
Identities = 92/257 (35%), Positives = 123/257 (47%), Gaps = 7/257 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH GS E V+LLL AH D T + TPL AA + +L+AHGAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLL---AHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD 420
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
N D +PLH+A + + LL+ GAC D + TPLH+AA + +LL
Sbjct: 421 ANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLL 480
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
++ AD GK T LH+AA GH +LL GA +D +TPLHLA
Sbjct: 481 VSRQADPNLHEAEGK-TPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGK 539
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ ++ L+ A A D G PLH A RG I ++LL GA + G+TPL
Sbjct: 540 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYL--ICKMLLRYGASLELPTHQGWTPL 597
Query: 358 HIAALNEFSACVLLLLD 374
H+AA + LL +
Sbjct: 598 HLAAYKGHLEIIHLLAE 614
Score = 124 bits (298), Expect = 2e-27
Identities = 89/242 (36%), Positives = 124/242 (51%), Gaps = 6/242 (2%)
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGA 209
E K TPLH + S+ V++L+AH DV+ S +PL A P++ LL GA
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGA 419
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ PLH AA G +LLL+ GA V A G T LHLAA++ AR
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGW-TPLHLAAQNNFENVAR 478
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ A + G+TPLH+A + +V++L + A++ A+ + RTPLH A+ RG
Sbjct: 479 LLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERG 538
Query: 330 -ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVS 388
RA + LL +GA P+A D GY PLH AA +LL YG + L T+ G +
Sbjct: 539 KVRAI---QHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWT 595
Query: 389 AL 390
L
Sbjct: 596 PL 597
Score = 122 bits (293), Expect = 6e-27
Identities = 112/360 (31%), Positives = 156/360 (43%), Gaps = 18/360 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL VD D +G T L ++ + LLL HGA N D E PLH AA
Sbjct: 381 LLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVD---EDGWAPLHFAAQ 437
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++L+ HGA V+A + +PLH A ++ V + L+ A P+ + +TP
Sbjct: 438 NGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTP 497
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVAA G S KLL + GA++ A T LHLA E G + LL GA D
Sbjct: 498 LHVAAYFGHVSLVKLLTSQGAELDAQQR-NLRTPLHLAVERGKVRAIQHLLKSGAVPDAL 556
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ G PLH A + +ML+ A + G TPLH A +G +I LL
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGH--LEIIHLLAE 614
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
+ A+ A +TPLH+AA + A V LL G D G + L V+R
Sbjct: 615 SHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQR----- 669
Query: 402 PRYLCKFDDAVHVSEHELGDVDCELTIDFRPLVPCLTRGEAELLLAFVEI-PYWDVDNGV 460
F +++ EH +V + + P +G +L VE DV +GV
Sbjct: 670 ----STFLSVINLLEHH-ANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGV 724
Score = 114 bits (275), Expect = 9e-25
Identities = 93/285 (32%), Positives = 132/285 (46%), Gaps = 9/285 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+ DP+ + G+T LH++ G VKLL GA D+ TPLH A
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAE---LDAQQRNLRTPLHLAVE 536
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ ++ L+ GA +A S PLH A + K LL GA + P TP
Sbjct: 537 RGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTP 596
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G LL + A++ A+G T LHLAA G LL GA +
Sbjct: 597 LHLAAYKGHLEIIHLLAESHANM-GALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAA 655
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLHLA + V L++ A+V A++ G TP H A ++G A I ++L+
Sbjct: 656 EQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTA--ILKVLVE 713
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
AGA + D TPL + AL ++ L+ G + ++ T GG
Sbjct: 714 AGAQLDVQDGVSCTPLQL-ALRSRKQGIMSFLE-GKEPSVATLGG 756
Score = 103 bits (248), Expect = 2e-21
Identities = 78/232 (33%), Positives = 104/232 (44%), Gaps = 3/232 (1%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH+ V + E V+ LL D TPL +AA LLL GAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
G A LH AA++G ARLLLDHGA +D G TPLHLA V +LV
Sbjct: 424 VDEDGWAP-LHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVS 482
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
R AD +A+G+TPLH A G + +LL S GA+ +A TPLH+A
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFG--HVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKV 540
Query: 367 ACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+ LL G G L R +I + L ++ ++ + H+
Sbjct: 541 RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQ 592
Score = 90.2 bits (214), Expect = 2e-17
Identities = 73/222 (32%), Positives = 104/222 (46%), Gaps = 5/222 (2%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
LRT + A GK + LLK G PD LD +G LH + G K+LL +GA
Sbjct: 527 LRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGA-- 584
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVK 202
+ + T TPLH AA L + +L A++ A G + +PLH A VV
Sbjct: 585 -SLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVS 643
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL+ GA P+ + TPLH+A + LL A+V A G T HLAA
Sbjct: 644 ALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVG-WTPAHLAALK 702
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
G+ ++L++ GA +D + TPL LA ++ ++ L
Sbjct: 703 GNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL 744
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2
protein.
Length = 765
Score = 151 bits (365), Expect = 1e-35
Identities = 101/285 (35%), Positives = 141/285 (49%), Gaps = 7/285 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + +D+ G LH + G + +LLLDHGA D+ TPLH AA
Sbjct: 414 LLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGA---CVDAQEREGWTPLHLAAQ 470
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++L++ AD N ++ ++PLH A +VK L GA D Q TP
Sbjct: 471 NNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTP 530
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+A G + LL +GA V A+ LH AA G ++LL +GA ++ P
Sbjct: 531 LHLAVERGKVRAIQHLLKSGA-VPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP 589
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+G TPLHLA LE++ +L + A++ A A TPLH A G A + LL
Sbjct: 590 THQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEA--VVSALLQ 647
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
GADPNAA+ G+TPLH+A V+ LL++ +V R G
Sbjct: 648 CGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVG 692
Score = 133 bits (322), Expect = 2e-30
Identities = 99/294 (33%), Positives = 143/294 (48%), Gaps = 7/294 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + G T LHL+ E +LL+ A PN ++ +T PLH AA
Sbjct: 447 LLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKT---PLHVAAY 503
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ VK+L + GA+++A + R+PLH AV ++ LL++GA PD P
Sbjct: 504 FGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGP 563
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AA+ G K+LL GA + G T LHLAA GH E LL + A++
Sbjct: 564 LHTAAARGKYLICKMLLRYGASLELPTHQGW-TPLHLAAYKGHLEIIHLLAESHANMGAL 622
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
TPLHLA VV L+ AD A + G TPLH A+ R I LL
Sbjct: 623 GAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVIN--LLE 680
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
A+ +A + G+TP H+AAL +A + +L++ G + ++ + L +R
Sbjct: 681 HHANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALR 734
Score = 126 bits (304), Expect = 3e-28
Identities = 92/257 (35%), Positives = 123/257 (47%), Gaps = 7/257 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH GS E V+LLL AH D T + TPL AA + +L+AHGAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLL---AHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGAD 420
Query: 179 VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
N D +PLH+A + + LL+ GAC D + TPLH+AA + +LL
Sbjct: 421 ANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLL 480
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
++ AD GK T LH+AA GH +LL GA +D +TPLHLA
Sbjct: 481 VSRQADPNLHEAEGK-TPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGK 539
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ ++ L+ A A D G PLH A RG I ++LL GA + G+TPL
Sbjct: 540 VRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYL--ICKMLLRYGASLELPTHQGWTPL 597
Query: 358 HIAALNEFSACVLLLLD 374
H+AA + LL +
Sbjct: 598 HLAAYKGHLEIIHLLAE 614
Score = 124 bits (298), Expect = 2e-27
Identities = 89/242 (36%), Positives = 124/242 (51%), Gaps = 6/242 (2%)
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDRSPLHYAVLSDAPEVVKELLEAGA 209
E K TPLH + S+ V++L+AH DV+ S +PL A P++ LL GA
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGA 419
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ PLH AA G +LLL+ GA V A G T LHLAA++ AR
Sbjct: 420 DANRVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGW-TPLHLAAQNNFENVAR 478
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ A + G+TPLH+A + +V++L + A++ A+ + RTPLH A+ RG
Sbjct: 479 LLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERG 538
Query: 330 -ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVS 388
RA + LL +GA P+A D GY PLH AA +LL YG + L T+ G +
Sbjct: 539 KVRAI---QHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWT 595
Query: 389 AL 390
L
Sbjct: 596 PL 597
Score = 122 bits (293), Expect = 6e-27
Identities = 112/360 (31%), Positives = 156/360 (43%), Gaps = 18/360 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL VD D +G T L ++ + LLL HGA N D E PLH AA
Sbjct: 381 LLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVD---EDGWAPLHFAAQ 437
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++L+ HGA V+A + +PLH A ++ V + L+ A P+ + +TP
Sbjct: 438 NGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVSRQADPNLHEAEGKTP 497
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVAA G S KLL + GA++ A T LHLA E G + LL GA D
Sbjct: 498 LHVAAYFGHVSLVKLLTSQGAELDAQQR-NLRTPLHLAVERGKVRAIQHLLKSGAVPDAL 556
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ G PLH A + +ML+ A + G TPLH A +G +I LL
Sbjct: 557 DQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGH--LEIIHLLAE 614
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
+ A+ A +TPLH+AA + A V LL G D G + L V+R
Sbjct: 615 SHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTPLHLAVQR----- 669
Query: 402 PRYLCKFDDAVHVSEHELGDVDCELTIDFRPLVPCLTRGEAELLLAFVEI-PYWDVDNGV 460
F +++ EH +V + + P +G +L VE DV +GV
Sbjct: 670 ----STFLSVINLLEHH-ANVHARNKVGWTPAHLAALKGNTAILKVLVEAGAQLDVQDGV 724
Score = 114 bits (275), Expect = 9e-25
Identities = 93/285 (32%), Positives = 132/285 (46%), Gaps = 9/285 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+ DP+ + G+T LH++ G VKLL GA D+ TPLH A
Sbjct: 480 LVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAE---LDAQQRNLRTPLHLAVE 536
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ ++ L+ GA +A S PLH A + K LL GA + P TP
Sbjct: 537 RGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQGWTP 596
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA G LL + A++ A+G T LHLAA G LL GA +
Sbjct: 597 LHLAAYKGHLEIIHLLAESHANM-GALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAA 655
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
G TPLHLA + V L++ A+V A++ G TP H A ++G A I ++L+
Sbjct: 656 EQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALKGNTA--ILKVLVE 713
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
AGA + D TPL + AL ++ L+ G + ++ T GG
Sbjct: 714 AGAQLDVQDGVSCTPLQL-ALRSRKQGIMSFLE-GKEPSVATLGG 756
Score = 103 bits (248), Expect = 2e-21
Identities = 78/232 (33%), Positives = 104/232 (44%), Gaps = 3/232 (1%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH+ V + E V+ LL D TPL +AA LLL GAD
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANR 423
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
G A LH AA++G ARLLLDHGA +D G TPLHLA V +LV
Sbjct: 424 VDEDGWAP-LHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVS 482
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
R AD +A+G+TPLH A G + +LL S GA+ +A TPLH+A
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFG--HVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKV 540
Query: 367 ACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+ LL G G L R +I + L ++ ++ + H+
Sbjct: 541 RAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELPTHQ 592
Score = 90.2 bits (214), Expect = 2e-17
Identities = 73/222 (32%), Positives = 104/222 (46%), Gaps = 5/222 (2%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
LRT + A GK + LLK G PD LD +G LH + G K+LL +GA
Sbjct: 527 LRTPLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGA-- 584
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVK 202
+ + T TPLH AA L + +L A++ A G + +PLH A VV
Sbjct: 585 -SLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVS 643
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL+ GA P+ + TPLH+A + LL A+V A G T HLAA
Sbjct: 644 ALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVG-WTPAHLAALK 702
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
G+ ++L++ GA +D + TPL LA ++ ++ L
Sbjct: 703 GNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIMSFL 744
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 149 bits (362), Expect = 3e-35
Identities = 103/286 (36%), Positives = 142/286 (49%), Gaps = 12/286 (4%)
Query: 102 KLLKMGVDPDELD---DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
KL+K+ + P ++D D+G + LHL+ G EEC K LL + A+PN S +TPLH
Sbjct: 421 KLMKI-LQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNL---SNRRGSTPLH 476
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
A + V++L+A VNA D+ + LH+A + + LLE A +
Sbjct: 477 MAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GA 276
TP+HVA G + ++LL G DV + G LH AA GH +LL G
Sbjct: 537 GRTPMHVACQHGQENIVRILLRRGVDV-SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ G+TPLHLA V +L+D C+DV +TPLH A G + A
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTS--TA 653
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
RLLL GA A + GYT LH+AA N A V LL++ DV R
Sbjct: 654 RLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLAR 699
Score = 118 bits (283), Expect = 1e-25
Identities = 95/299 (31%), Positives = 138/299 (46%), Gaps = 12/299 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL + + D+ T LH + G E +LLL+ A N D T P+H A
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT---PMHVACQ 546
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL-EAGACPDTPQVFTET 220
V++L+ G DV+ D PLHYA +VK L + G + + T
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRT 606
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G ++L++ +DV + T LH+AAE GH ARLLL GA +
Sbjct: 607 PLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ-TPLHVAAETGHTSTARLLLHRGAGKEA 665
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G T LHLA L V++LV+ ADV A+ +T LH A G ++ L+
Sbjct: 666 VTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG--HSEVVEELV 723
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT---NGGVSALSFIVRR 396
SA + D G + LH+AA + V LL +G + L++ GG + ++RR
Sbjct: 724 SADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRR 781
Score = 112 bits (269), Expect = 5e-24
Identities = 95/259 (36%), Positives = 125/259 (48%), Gaps = 14/259 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +A G LL+ +E+D GRT +H++C G E V++LL G
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGV---- 561
Query: 146 WDSSTETKAT--PLHCAASAKSLACVKVLIAH-GADVNA-GLSDRSPLHYAVLSDAPEVV 201
D S + K PLH AA L VK+L G VNA L R+PLH A V
Sbjct: 562 -DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVA 620
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L++ + + + +TPLHVAA G S +LLL+ GA A G TALHLAA
Sbjct: 621 RILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDG-YTALHLAAR 679
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRT 320
+GH +LL++ A + QT LHLA EVVE LV ADV D G +
Sbjct: 680 NGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVS--ADVIDLFDEQGLS 737
Query: 321 PLHGAIVRGARACDIARLL 339
LH A +G A + LL
Sbjct: 738 ALHLA-AQGRHAQTVETLL 755
Score = 89.4 bits (212), Expect = 4e-17
Identities = 81/239 (33%), Positives = 108/239 (45%), Gaps = 7/239 (2%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
AS E F RT + AC G+ ++ LL+ GVD LH + G VK
Sbjct: 528 ASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK 587
Query: 135 LLLDH-GAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYA 192
LL G N + T TPLH AA ++LI +DVN L ++PLH A
Sbjct: 588 LLAKQPGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVA 644
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ + LL GA + T LH+AA G + KLL+ ADV A GP
Sbjct: 645 AETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADV-LARGPLN 703
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
TALHLAA GH+E L+ ID + +G + LHLA + + VE L+ A +
Sbjct: 704 QTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHI 761
Score = 38.7 bits (86), Expect = 0.074
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A+ G C A+ LL A+PN ++ G TPLH+A V LLL
Sbjct: 438 GASLLHLAVEAGQEEC--AKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 495
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
V + +AL F + + R L + + +V+ + E
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 149 bits (362), Expect = 3e-35
Identities = 103/286 (36%), Positives = 142/286 (49%), Gaps = 12/286 (4%)
Query: 102 KLLKMGVDPDELD---DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
KL+K+ + P ++D D+G + LHL+ G EEC K LL + A+PN S +TPLH
Sbjct: 421 KLMKI-LQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNL---SNRRGSTPLH 476
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
A + V++L+A VNA D+ + LH+A + + LLE A +
Sbjct: 477 MAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GA 276
TP+HVA G + ++LL G DV + G LH AA GH +LL G
Sbjct: 537 GRTPMHVACQHGQENIVRILLRRGVDV-SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ G+TPLHLA V +L+D C+DV +TPLH A G + A
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTS--TA 653
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
RLLL GA A + GYT LH+AA N A V LL++ DV R
Sbjct: 654 RLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLAR 699
Score = 118 bits (283), Expect = 1e-25
Identities = 95/299 (31%), Positives = 138/299 (46%), Gaps = 12/299 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL + + D+ T LH + G E +LLL+ A N D T P+H A
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT---PMHVACQ 546
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL-EAGACPDTPQVFTET 220
V++L+ G DV+ D PLHYA +VK L + G + + T
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRT 606
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G ++L++ +DV + T LH+AAE GH ARLLL GA +
Sbjct: 607 PLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ-TPLHVAAETGHTSTARLLLHRGAGKEA 665
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G T LHLA L V++LV+ ADV A+ +T LH A G ++ L+
Sbjct: 666 VTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG--HSEVVEELV 723
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT---NGGVSALSFIVRR 396
SA + D G + LH+AA + V LL +G + L++ GG + ++RR
Sbjct: 724 SADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRR 781
Score = 112 bits (269), Expect = 5e-24
Identities = 95/259 (36%), Positives = 125/259 (48%), Gaps = 14/259 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +A G LL+ +E+D GRT +H++C G E V++LL G
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGV---- 561
Query: 146 WDSSTETKAT--PLHCAASAKSLACVKVLIAH-GADVNA-GLSDRSPLHYAVLSDAPEVV 201
D S + K PLH AA L VK+L G VNA L R+PLH A V
Sbjct: 562 -DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVA 620
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L++ + + + +TPLHVAA G S +LLL+ GA A G TALHLAA
Sbjct: 621 RILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDG-YTALHLAAR 679
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRT 320
+GH +LL++ A + QT LHLA EVVE LV ADV D G +
Sbjct: 680 NGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVS--ADVIDLFDEQGLS 737
Query: 321 PLHGAIVRGARACDIARLL 339
LH A +G A + LL
Sbjct: 738 ALHLA-AQGRHAQTVETLL 755
Score = 89.4 bits (212), Expect = 4e-17
Identities = 81/239 (33%), Positives = 108/239 (45%), Gaps = 7/239 (2%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
AS E F RT + AC G+ ++ LL+ GVD LH + G VK
Sbjct: 528 ASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK 587
Query: 135 LLLDH-GAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYA 192
LL G N + T TPLH AA ++LI +DVN L ++PLH A
Sbjct: 588 LLAKQPGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVA 644
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ + LL GA + T LH+AA G + KLL+ ADV A GP
Sbjct: 645 AETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADV-LARGPLN 703
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
TALHLAA GH+E L+ ID + +G + LHLA + + VE L+ A +
Sbjct: 704 QTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHI 761
Score = 38.7 bits (86), Expect = 0.074
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A+ G C A+ LL A+PN ++ G TPLH+A V LLL
Sbjct: 438 GASLLHLAVEAGQEEC--AKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 495
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
V + +AL F + + R L + + +V+ + E
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 149 bits (362), Expect = 3e-35
Identities = 103/286 (36%), Positives = 142/286 (49%), Gaps = 12/286 (4%)
Query: 102 KLLKMGVDPDELD---DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
KL+K+ + P ++D D+G + LHL+ G EEC K LL + A+PN S +TPLH
Sbjct: 421 KLMKI-LQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNL---SNRRGSTPLH 476
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
A + V++L+A VNA D+ + LH+A + + LLE A +
Sbjct: 477 MAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GA 276
TP+HVA G + ++LL G DV + G LH AA GH +LL G
Sbjct: 537 GRTPMHVACQHGQENIVRILLRRGVDV-SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ G+TPLHLA V +L+D C+DV +TPLH A G + A
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTS--TA 653
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
RLLL GA A + GYT LH+AA N A V LL++ DV R
Sbjct: 654 RLLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLAR 699
Score = 116 bits (280), Expect = 2e-25
Identities = 95/299 (31%), Positives = 137/299 (45%), Gaps = 12/299 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL + + D+ T LH + G E +LLL+ A N D T P+H A
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT---PMHVACQ 546
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL-EAGACPDTPQVFTET 220
V++L+ G DV+ D PLHYA +VK L + G + + T
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRT 606
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G ++L++ +DV + T LH+AAE GH ARLLL GA
Sbjct: 607 PLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ-TPLHVAAETGHTSTARLLLHRGAGKKA 665
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G T LHLA L V++LV+ ADV A+ +T LH A G ++ L+
Sbjct: 666 VTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG--HSEVVEELV 723
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT---NGGVSALSFIVRR 396
SA + D G + LH+AA + V LL +G + L++ GG + ++RR
Sbjct: 724 SADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRR 781
Score = 113 bits (271), Expect = 3e-24
Identities = 95/259 (36%), Positives = 126/259 (48%), Gaps = 14/259 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +A G LL+ +E+D GRT +H++C G E V++LL G
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGV---- 561
Query: 146 WDSSTETKAT--PLHCAASAKSLACVKVLIAH-GADVNA-GLSDRSPLHYAVLSDAPEVV 201
D S + K PLH AA L VK+L G VNA L R+PLH A V
Sbjct: 562 -DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVA 620
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L++ + + + +TPLHVAA G S +LLL+ GA +A G TALHLAA
Sbjct: 621 RILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKKAVTSDG-YTALHLAAR 679
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRT 320
+GH +LL++ A + QT LHLA EVVE LV ADV D G +
Sbjct: 680 NGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVS--ADVIDLFDEQGLS 737
Query: 321 PLHGAIVRGARACDIARLL 339
LH A +G A + LL
Sbjct: 738 ALHLA-AQGRHAQTVETLL 755
Score = 91.9 bits (218), Expect = 8e-18
Identities = 79/250 (31%), Positives = 109/250 (43%), Gaps = 7/250 (2%)
Query: 135 LLLDHGAHPNTWDSSTET--KATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYA 192
L L P+T D T K + S + +K+L D+ S S LH A
Sbjct: 387 LSLSFEREPSTSDLGTTDVQKKKLVDAIVSGDTSKLMKILQPQDVDLALD-SGASLLHLA 445
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
V + E K LL A P+ TPLH+A +LLL V A +
Sbjct: 446 VEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAK-DEDQ 504
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
TALH AA++G RLLL+ A ++ +F G+TP+H+A +V +L+ R DV
Sbjct: 505 WTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVS 564
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLL-SAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+ D PLH A +G I +LL G NA G TPLH+AA +
Sbjct: 565 LQGKDAWLPLHYAAWQG--HLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVARI 622
Query: 372 LLDYGGDVTL 381
L+D DV +
Sbjct: 623 LIDLCSDVNV 632
Score = 88.2 bits (209), Expect = 9e-17
Identities = 81/239 (33%), Positives = 107/239 (44%), Gaps = 7/239 (2%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
AS E F RT + AC G+ ++ LL+ GVD LH + G VK
Sbjct: 528 ASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK 587
Query: 135 LLLDH-GAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYA 192
LL G N + T TPLH AA ++LI +DVN L ++PLH A
Sbjct: 588 LLAKQPGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVA 644
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ + LL GA T LH+AA G + KLL+ ADV A GP
Sbjct: 645 AETGHTSTARLLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADV-LARGPLN 703
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
TALHLAA GH+E L+ ID + +G + LHLA + + VE L+ A +
Sbjct: 704 QTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHI 761
Score = 38.7 bits (86), Expect = 0.074
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A+ G C A+ LL A+PN ++ G TPLH+A V LLL
Sbjct: 438 GASLLHLAVEAGQEEC--AKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 495
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
V + +AL F + + R L + + +V+ + E
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 149 bits (362), Expect = 3e-35
Identities = 103/286 (36%), Positives = 142/286 (49%), Gaps = 12/286 (4%)
Query: 102 KLLKMGVDPDELD---DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
KL+K+ + P ++D D+G + LHL+ G EEC K LL + A+PN S +TPLH
Sbjct: 421 KLMKI-LQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNL---SNRRGSTPLH 476
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
A + V++L+A VNA D+ + LH+A + + LLE A +
Sbjct: 477 MAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GA 276
TP+HVA G + ++LL G DV + G LH AA GH +LL G
Sbjct: 537 GRTPMHVACQHGQENIVRILLRRGVDV-SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ G+TPLHLA V +L+D C+DV +TPLH A G + A
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTS--TA 653
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
RLLL GA A + GYT LH+AA N A V LL++ DV R
Sbjct: 654 RLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLAR 699
Score = 118 bits (283), Expect = 1e-25
Identities = 95/299 (31%), Positives = 138/299 (46%), Gaps = 12/299 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL + + D+ T LH + G E +LLL+ A N D T P+H A
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT---PMHVACQ 546
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL-EAGACPDTPQVFTET 220
V++L+ G DV+ D PLHYA +VK L + G + + T
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRT 606
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G ++L++ +DV + T LH+AAE GH ARLLL GA +
Sbjct: 607 PLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ-TPLHVAAETGHTSTARLLLHRGAGKEA 665
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G T LHLA L V++LV+ ADV A+ +T LH A G ++ L+
Sbjct: 666 VTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG--HSEVVEELV 723
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT---NGGVSALSFIVRR 396
SA + D G + LH+AA + V LL +G + L++ GG + ++RR
Sbjct: 724 SADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRR 781
Score = 112 bits (269), Expect = 5e-24
Identities = 95/259 (36%), Positives = 125/259 (48%), Gaps = 14/259 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +A G LL+ +E+D GRT +H++C G E V++LL G
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGV---- 561
Query: 146 WDSSTETKAT--PLHCAASAKSLACVKVLIAH-GADVNA-GLSDRSPLHYAVLSDAPEVV 201
D S + K PLH AA L VK+L G VNA L R+PLH A V
Sbjct: 562 -DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVA 620
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L++ + + + +TPLHVAA G S +LLL+ GA A G TALHLAA
Sbjct: 621 RILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDG-YTALHLAAR 679
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRT 320
+GH +LL++ A + QT LHLA EVVE LV ADV D G +
Sbjct: 680 NGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVS--ADVIDLFDEQGLS 737
Query: 321 PLHGAIVRGARACDIARLL 339
LH A +G A + LL
Sbjct: 738 ALHLA-AQGRHAQTVETLL 755
Score = 89.4 bits (212), Expect = 4e-17
Identities = 81/239 (33%), Positives = 108/239 (45%), Gaps = 7/239 (2%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
AS E F RT + AC G+ ++ LL+ GVD LH + G VK
Sbjct: 528 ASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK 587
Query: 135 LLLDH-GAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYA 192
LL G N + T TPLH AA ++LI +DVN L ++PLH A
Sbjct: 588 LLAKQPGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVA 644
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ + LL GA + T LH+AA G + KLL+ ADV A GP
Sbjct: 645 AETGHTSTARLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADV-LARGPLN 703
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
TALHLAA GH+E L+ ID + +G + LHLA + + VE L+ A +
Sbjct: 704 QTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHI 761
Score = 38.7 bits (86), Expect = 0.074
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A+ G C A+ LL A+PN ++ G TPLH+A V LLL
Sbjct: 438 GASLLHLAVEAGQEEC--AKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 495
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
V + +AL F + + R L + + +V+ + E
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 149 bits (361), Expect = 4e-35
Identities = 103/286 (36%), Positives = 142/286 (49%), Gaps = 12/286 (4%)
Query: 102 KLLKMGVDPDELD---DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
KL+K+ + P ++D D+G + LHL+ G EEC K LL + A+PN S +TPLH
Sbjct: 469 KLMKI-LQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNL---SNRRGSTPLH 524
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
A + V++L+A VNA D+ + LH+A + + LLE A +
Sbjct: 525 MAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 584
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GA 276
TP+HVA G + ++LL G DV + G LH AA GH +LL G
Sbjct: 585 GRTPMHVACQHGQENIVRILLRRGVDV-SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 643
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ G+TPLHLA V +L+D C+DV +TPLH A G + A
Sbjct: 644 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTS--TA 701
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
RLLL GA A + GYT LH+AA N A V LL++ DV R
Sbjct: 702 RLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLAR 747
Score = 118 bits (283), Expect = 1e-25
Identities = 95/299 (31%), Positives = 138/299 (46%), Gaps = 12/299 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL + + D+ T LH + G E +LLL+ A N D T P+H A
Sbjct: 538 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRT---PMHVACQ 594
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL-EAGACPDTPQVFTET 220
V++L+ G DV+ D PLHYA +VK L + G + + T
Sbjct: 595 HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRT 654
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH+AA G ++L++ +DV + T LH+AAE GH ARLLL GA +
Sbjct: 655 PLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ-TPLHVAAETGHTSTARLLLHRGAGKEA 713
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
G T LHLA L V++LV+ ADV A+ +T LH A G ++ L+
Sbjct: 714 MTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG--HSEVVEELV 771
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT---NGGVSALSFIVRR 396
SA + D G + LH+AA + V LL +G + L++ GG + ++RR
Sbjct: 772 SADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRR 829
Score = 111 bits (268), Expect = 7e-24
Identities = 95/259 (36%), Positives = 125/259 (48%), Gaps = 14/259 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +A G LL+ +E+D GRT +H++C G E V++LL G
Sbjct: 554 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRRGV---- 609
Query: 146 WDSSTETKAT--PLHCAASAKSLACVKVLIAH-GADVNA-GLSDRSPLHYAVLSDAPEVV 201
D S + K PLH AA L VK+L G VNA L R+PLH A V
Sbjct: 610 -DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVA 668
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L++ + + + +TPLHVAA G S +LLL+ GA A G TALHLAA
Sbjct: 669 RILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAMTSDG-YTALHLAAR 727
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRT 320
+GH +LL++ A + QT LHLA EVVE LV ADV D G +
Sbjct: 728 NGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVS--ADVIDLFDEQGLS 785
Query: 321 PLHGAIVRGARACDIARLL 339
LH A +G A + LL
Sbjct: 786 ALHLA-AQGRHAQTVETLL 803
Score = 89.4 bits (212), Expect = 4e-17
Identities = 81/239 (33%), Positives = 108/239 (45%), Gaps = 7/239 (2%)
Query: 75 ASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVK 134
AS E F RT + AC G+ ++ LL+ GVD LH + G VK
Sbjct: 576 ASVNEVDFEGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVK 635
Query: 135 LLLDH-GAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYA 192
LL G N + T TPLH AA ++LI +DVN L ++PLH A
Sbjct: 636 LLAKQPGVSVN---AQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVA 692
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ + LL GA + T LH+AA G + KLL+ ADV A GP
Sbjct: 693 AETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADV-LARGPLN 751
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
TALHLAA GH+E L+ ID + +G + LHLA + + VE L+ A +
Sbjct: 752 QTALHLAAAHGHSEVVEELVSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHI 809
Score = 38.7 bits (86), Expect = 0.074
Identities = 30/101 (29%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A+ G C A+ LL A+PN ++ G TPLH+A V LLL
Sbjct: 486 GASLLHLAVEAGQEEC--AKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKI 543
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
V + +AL F + + R L + + +V+ + E
Sbjct: 544 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 584
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 147 bits (355), Expect = 2e-34
Identities = 103/286 (36%), Positives = 141/286 (49%), Gaps = 12/286 (4%)
Query: 102 KLLKMGVDPDELD---DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
KL+K+ + P ++D D+G + LHL+ G EEC K LL + A+PN S +TPLH
Sbjct: 421 KLMKI-LQPQDVDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNL---SNRRGSTPLH 476
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
A + V+ L+A VNA D+ + LH+A + + LLE A +
Sbjct: 477 MAVERRVRGVVERLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GA 276
TP+HVA G + ++LL G DV + G LH AA GH +LL G
Sbjct: 537 GLTPMHVACQHGQENIVRILLRRGVDV-SLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ G+TPLHLA V +L+D C+DV +TPLH A G + A
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTS--TA 653
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
RLLL GA A + GYT LH+AA N A V LL++ DV R
Sbjct: 654 RLLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLAR 699
Score = 118 bits (284), Expect = 8e-26
Identities = 95/300 (31%), Positives = 139/300 (46%), Gaps = 12/300 (4%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+LL + + D+ T LH + G E +LLL+ A N D TP+H A
Sbjct: 489 RLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEG---LTPMHVAC 545
Query: 162 SAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL-EAGACPDTPQVFTE 219
V++L+ G DV+ D PLHYA +VK L + G + +
Sbjct: 546 QHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGR 605
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
TPLH+AA G ++L++ +DV + T LH+AAE GH ARLLL GA +
Sbjct: 606 TPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQ-TPLHVAAETGHTSTARLLLHRGAGKE 664
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
G T LHLA L V++LV+ ADV A+ +T LH A G ++ L
Sbjct: 665 AVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG--HSEVVEEL 722
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT---NGGVSALSFIVRR 396
+SA + D G + LH+AA + V LL +G + L++ GG + ++RR
Sbjct: 723 VSADV-IDLFDEQGLSALHLAAQGRHAQTVETLLRHGAHINLQSLKFQGGHGPAATLLRR 781
Score = 109 bits (262), Expect = 4e-23
Identities = 94/259 (36%), Positives = 124/259 (47%), Gaps = 14/259 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +A G LL+ +E+D G T +H++C G E V++LL G
Sbjct: 506 TALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQENIVRILLRRGV---- 561
Query: 146 WDSSTETKAT--PLHCAASAKSLACVKVLIAH-GADVNA-GLSDRSPLHYAVLSDAPEVV 201
D S + K PLH AA L VK+L G VNA L R+PLH A V
Sbjct: 562 -DVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLAAQRGHYRVA 620
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L++ + + + +TPLHVAA G S +LLL+ GA A G TALHLAA
Sbjct: 621 RILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARLLLHRGAGKEAVTSDG-YTALHLAAR 679
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRT 320
+GH +LL++ A + QT LHLA EVVE LV ADV D G +
Sbjct: 680 NGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVS--ADVIDLFDEQGLS 737
Query: 321 PLHGAIVRGARACDIARLL 339
LH A +G A + LL
Sbjct: 738 ALHLA-AQGRHAQTVETLL 755
Score = 36.3 bits (80), Expect = 0.40
Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A+ G C A+ LL A+PN ++ G TPLH+A V LL
Sbjct: 438 GASLLHLAVEAGQEEC--AKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVVERLLARKI 495
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
V + +AL F + + R L + + +V+ + E
Sbjct: 496 SVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFE 536
>BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein.
Length = 367
Score = 140 bits (340), Expect = 1e-32
Identities = 95/266 (35%), Positives = 141/266 (53%), Gaps = 7/266 (2%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-R 186
G E +++L+ NT DS K TPLH AA +++LI GA VNA +
Sbjct: 19 GDPEEIRMLIHKTEDVNTLDSE---KRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWL 75
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH AV S + E V+ L++ A + +TPLHVAA+ + C ++++ + V
Sbjct: 76 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV 135
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
+ G+ TALH AA +GH E LLL GA+I+ + + + LH A L+VV +L++
Sbjct: 136 SDRGGR-TALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLIN 194
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
A+V KD G TPLH A G ++ + LL+ G + + + +G T LHIA N
Sbjct: 195 HGAEVTCKDKKGYTPLHAAASNGQ--INVVKHLLNLGVEIDEINVYGNTALHIACYNGQD 252
Query: 367 ACVLLLLDYGGDVTLRTNGGVSALSF 392
A V L+DYG +V N G + L F
Sbjct: 253 AVVNELIDYGANVNQPNNNGFTPLHF 278
Score = 133 bits (322), Expect = 2e-30
Identities = 102/312 (32%), Positives = 150/312 (48%), Gaps = 6/312 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A +LG + ++ L+ G + D+ T LH + SEE V++L+ H A N
Sbjct: 42 RTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 101
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
D + + TPLH AA+ K++ C +V+I + VN + R+ LH+A L+ E+V
Sbjct: 102 ARDKNWQ---TPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNL 158
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LL GA + LH AA +G LL+N GA+V G T LH AA +G
Sbjct: 159 LLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKG-YTPLHAAASNG 217
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
+ LL+ G ID N G T LH+A VV L+D A+V + +G TPLH
Sbjct: 218 QINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLH 277
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A A + LL++ GAD N G +PLH+ A++ L+ GG++
Sbjct: 278 FAAASTHGALCL-ELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVD 336
Query: 384 NGGVSALSFIVR 395
G + L R
Sbjct: 337 KDGNTPLHVAAR 348
Score = 127 bits (306), Expect = 2e-28
Identities = 90/278 (32%), Positives = 135/278 (48%), Gaps = 8/278 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K D + D +T LH++ + +C ++++ + N D T LH AA
Sbjct: 93 LIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTA---LHHAAL 149
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V +L+A GA++NA DR LH+A +VV L+ GA TP
Sbjct: 150 NGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTP 209
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AAS G + K LLN G ++ G TALH+A +G L+D+GA+++ P
Sbjct: 210 LHAAASNGQINVVKHLLNLGVEIDEINVYGN-TALHIACYNGQDAVVNELIDYGANVNQP 268
Query: 282 NFRGQTPLHLATLA-QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N G TPLH A + +E+LV+ ADV + DG++PLH V G ++ L+
Sbjct: 269 NNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTR--SQTLI 326
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
G + + D G TPLH+AA + L+ G D
Sbjct: 327 QNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 364
Score = 108 bits (259), Expect = 8e-23
Identities = 70/208 (33%), Positives = 106/208 (50%), Gaps = 3/208 (1%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
L+D+ PL A+ S PE ++ L+ +T TPLHVAA LG A +LL+ +GA
Sbjct: 6 LTDQPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGA 65
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
V A T LH A E ++L+ H A ++ + QTPLH+A ++++ E
Sbjct: 66 RVNAKDNMW-LTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAE 124
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
+++ + V D GRT LH A + G ++ LLL+ GA+ NA D LH AA
Sbjct: 125 VIIPLLSSVNVSDRGGRTALHHAALNG--HVEMVNLLLAKGANINAFDKKDRRALHWAAY 182
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSAL 390
V LL+++G +VT + G + L
Sbjct: 183 MGHLDVVALLINHGAEVTCKDKKGYTPL 210
Score = 103 bits (248), Expect = 2e-21
Identities = 77/230 (33%), Positives = 112/230 (48%), Gaps = 6/230 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G RTA+ A G ++ LL G + + D R LH + +G + V LL++HGA
Sbjct: 139 GGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 198
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVV 201
D + TPLH AAS + VK L+ G +++ + + LH A + VV
Sbjct: 199 VTCKD---KKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 255
Query: 202 KELLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAA 260
EL++ GA + P TPLH AAS A C +LL+N GADV GK + LH+ A
Sbjct: 256 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGK-SPLHMTA 314
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCAD 310
G ++ L+ +G ID + G TPLH+A ++ L+ AD
Sbjct: 315 VHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 364
>AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens
cDNA FLJ45589 fis, clone BRTHA3014547, weakly similar
to Ankyrin 1. ).
Length = 1375
Score = 134 bits (323), Expect = 1e-30
Identities = 108/337 (32%), Positives = 151/337 (44%), Gaps = 6/337 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A W G+ ++ LL+ G + ++ D+ GRT L + +G E V+ LLDHGA N
Sbjct: 591 RTALRAAAWGGREDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVN 650
Query: 145 --TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVV 201
D T L AS + V +LI GA+V+ D +PL A +VV
Sbjct: 651 HEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV 710
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
LLE GA D TPL AAS+G AS LL GA V + G+ T L +A+
Sbjct: 711 DLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGR-TVLSIASA 769
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
G+ E R LLD G + + G TPLH+A + E L+++ A D DGR P
Sbjct: 770 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIP 829
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A G C ++LL ++ + G L +AAL V LL +G DV
Sbjct: 830 FILASQEGHYDC--VQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNC 887
Query: 382 RTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+ G L + + Y + V S+ E
Sbjct: 888 KDADGRPTLYILALENQLTMAEYFLENGANVEASDAE 924
Score = 123 bits (297), Expect = 2e-27
Identities = 94/297 (31%), Positives = 145/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G + ++ L+ G + D D G T L ++ G + V LLL+ GA + D++ T
Sbjct: 672 GHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRT-- 729
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT 213
PL AAS + V L+ GA V++ S+ R+ L A EVV+ LL+ G +
Sbjct: 730 -PLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH 788
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPLH+AA G + L+ GA G+ + LA+++GH +C ++LL+
Sbjct: 789 RDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFI-LASQEGHYDCVQILLE 847
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+ ++ID + G+ L +A L ++VE+L ADV KDADGR L+ I+
Sbjct: 848 NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLY--ILALENQL 905
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A L GA+ A+D G T LH++ V +L+ Y DV N SAL
Sbjct: 906 TMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSAL 962
Score = 123 bits (296), Expect = 3e-27
Identities = 107/295 (36%), Positives = 134/295 (45%), Gaps = 12/295 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G ++ D GRT L + GS + V LL+ GA D+ T PL AA
Sbjct: 477 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHT---PLTLAAR 533
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V LI GA++N D + L A EVV LL AG D + T
Sbjct: 534 QGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTA 593
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L AA G LL GA+V A G+ TAL AA GH E LLDHGA ++
Sbjct: 594 LRAAAWGGREDIVLNLLQHGAEVNKADNEGR-TALIAAAYMGHREIVEHLLDHGAEVNHE 652
Query: 282 NFRGQTPLHLATLAQSLE-----VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
+ G+T L +A L VV +L+DR A+V D DG TPL A G D+
Sbjct: 653 DVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGH--VDVV 710
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
LLL GAD + DN G TPL AA ++ V LL +G V + G + LS
Sbjct: 711 DLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLS 765
Score = 118 bits (284), Expect = 8e-26
Identities = 105/324 (32%), Positives = 151/324 (46%), Gaps = 36/324 (11%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT +L A +G + ++ LL G D +D GRT L ++ G+ E V+ LLD G N
Sbjct: 728 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDEN 787
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKE 203
D + TPLH AA + LI GA N +D R P A + V+
Sbjct: 788 HRD---DAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQI 844
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LLE + D L VAA G +LL + GADV G+ T L++ A +
Sbjct: 845 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPT-LYILALEN 903
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL- 322
A L++GA+++ + G+T LH++ +E+V++L+ ADV A D + R+ L
Sbjct: 904 QLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQ 963
Query: 323 ----------------HGAIV-----RGARA-C--------DIARLLLSAGADPNAADNF 352
HGA+V +GA A C D+ ++LL GADPN AD F
Sbjct: 964 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 1023
Query: 353 GYTPLHIAALNEFSACVLLLLDYG 376
G T + +AA N S + LL YG
Sbjct: 1024 GRTAMRVAAKNGHSQIIKLLEKYG 1047
Score = 107 bits (258), Expect = 1e-22
Identities = 96/292 (32%), Positives = 132/292 (45%), Gaps = 10/292 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G + DD RT + + E+ ++ LLD+GA N DS+ T L AA
Sbjct: 446 LVKAGAHVNSEDD--RTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTL---LANAAY 500
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ SL V +L++ GAD+ +PL A +VV L+ GA + T
Sbjct: 501 SGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTA 560
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L AA G LL AG V A + TAL AA G + LL HGA ++
Sbjct: 561 LRSAAWGGHTEVVSALLYAGVKVDCADADSR-TALRAAAWGGREDIVLNLLQHGAEVNKA 619
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA---IVRGARACDIARL 338
+ G+T L A E+VE L+D A+V +D DGRT L A + + L
Sbjct: 620 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSL 679
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
L+ GA+ + D G TPL +AA V LLL+ G DV N G + L
Sbjct: 680 LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPL 731
Score = 105 bits (252), Expect = 6e-22
Identities = 97/311 (31%), Positives = 140/311 (45%), Gaps = 10/311 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G ++ L+ G D + D G T L L+ G + V L+ GA+ N
Sbjct: 492 RTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANIN 551
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKE 203
D + T L AA V L+ G V+ +D R+ L A ++V
Sbjct: 552 HTD---QDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGREDIVLN 608
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT----ALHLA 259
LL+ GA + T L AA +G + LL+ GA+V G+ AL +
Sbjct: 609 LLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 668
Query: 260 AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR 319
A GHA LL+D GA +D + G TPL +A ++VV++L++ ADV D +GR
Sbjct: 669 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 728
Query: 320 TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
TPL A G + LL GA ++ D+ G T L IA+ V LLD G D
Sbjct: 729 TPLLAAASMG--HASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE 786
Query: 380 TLRTNGGVSAL 390
R + G + L
Sbjct: 787 NHRDDAGWTPL 797
Score = 101 bits (242), Expect = 9e-21
Identities = 81/274 (29%), Positives = 132/274 (48%), Gaps = 9/274 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + A + G ++ L++ G +E+D+ GR L+ G +CV++LL++ ++
Sbjct: 795 TPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI-- 852
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKEL 204
D L AA V++L +HGADVN +D P L+ L + + +
Sbjct: 853 -DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYF 911
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
LE GA + T LHV+ G ++L+ ADV AA K +AL AA GH
Sbjct: 912 LENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNE-KRSALQSAAWQGH 970
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ +LL++HGA +D +G T L +A ++VV++L++ AD D GRT +
Sbjct: 971 VKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRV 1030
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
A G I +LL GA ++ + +P+H
Sbjct: 1031 AAKNG--HSQIIKLLEKYGA--SSLNGCSPSPVH 1060
Score = 89.8 bits (213), Expect = 3e-17
Identities = 79/235 (33%), Positives = 104/235 (44%), Gaps = 4/235 (1%)
Query: 164 KSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
K +++L+ GA VN+ DR+ + + ++ LL+ GA + T L
Sbjct: 438 KEQEVLQLLVKAGAHVNSE-DDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLA 496
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
AA GS LL++ GAD+ G T L LAA GH + L+ GA+I+ +
Sbjct: 497 NAAYSGSLDVVNLLVSRGADLEIEDAHGH-TPLTLAARQGHTKVVNCLIGCGANINHTDQ 555
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAG 343
G T L A EVV L+ V DAD RT L A G DI LL G
Sbjct: 556 DGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGRE--DIVLNLLQHG 613
Query: 344 ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
A+ N ADN G T L AA V LLD+G +V G +ALS VP
Sbjct: 614 AEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 668
Score = 75.8 bits (178), Expect = 5e-13
Identities = 63/197 (31%), Positives = 96/197 (48%), Gaps = 5/197 (2%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+ R A+ A G ++ L G D + D GR L++ L + L++G
Sbjct: 856 GYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENG 915
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPE 199
A+ D+ T LH + + V+VLIA+ ADVNA ++ RS L A +
Sbjct: 916 ANVEASDAEGR---TALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 972
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
VV+ L+E GA D T L +AA G ++LL GAD A G+ TA+ +A
Sbjct: 973 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGR-TAMRVA 1031
Query: 260 AEDGHAECARLLLDHGA 276
A++GH++ +LL +GA
Sbjct: 1032 AKNGHSQIIKLLEKYGA 1048
>BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein
protein.
Length = 1280
Score = 132 bits (320), Expect = 3e-30
Identities = 108/337 (32%), Positives = 150/337 (44%), Gaps = 6/337 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A W G ++ LL+ G + ++ D+ GRT L + +G E V+ LLDHGA N
Sbjct: 496 RTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVN 555
Query: 145 --TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVV 201
D T L AS + V +LI GA+V+ D +PL A +VV
Sbjct: 556 HEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV 615
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
LLE GA D TPL AAS+G AS LL GA V + G+ T L +A+
Sbjct: 616 DLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGR-TVLSIASA 674
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
G+ E R LLD G + + G TPLH+A + E L+++ A D DGR P
Sbjct: 675 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIP 734
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A G C ++LL ++ + G L +AAL V LL +G DV
Sbjct: 735 FILASQEGHYDC--VQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNC 792
Query: 382 RTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+ G L + + Y + V S+ E
Sbjct: 793 KDADGRPTLYILALENQLTMAEYFLENGANVEASDAE 829
Score = 123 bits (297), Expect = 2e-27
Identities = 94/297 (31%), Positives = 145/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G + ++ L+ G + D D G T L ++ G + V LLL+ GA + D++ T
Sbjct: 577 GHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRT-- 634
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT 213
PL AAS + V L+ GA V++ S+ R+ L A EVV+ LL+ G +
Sbjct: 635 -PLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH 693
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPLH+AA G + L+ GA G+ + LA+++GH +C ++LL+
Sbjct: 694 RDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFI-LASQEGHYDCVQILLE 752
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+ ++ID + G+ L +A L ++VE+L ADV KDADGR L+ I+
Sbjct: 753 NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLY--ILALENQL 810
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A L GA+ A+D G T LH++ V +L+ Y DV N SAL
Sbjct: 811 TMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSAL 867
Score = 123 bits (296), Expect = 3e-27
Identities = 107/295 (36%), Positives = 134/295 (45%), Gaps = 12/295 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G ++ D GRT L + GS + V LL+ GA D+ T PL AA
Sbjct: 382 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHT---PLTLAAR 438
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V LI GA++N D + L A EVV LL AG D + T
Sbjct: 439 QGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTA 498
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L AA G LL GA+V A G+ TAL AA GH E LLDHGA ++
Sbjct: 499 LRAAAWGGHEDIVLNLLQHGAEVNKADNEGR-TALIAAAYMGHREIVEHLLDHGAEVNHE 557
Query: 282 NFRGQTPLHLATLAQSLE-----VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
+ G+T L +A L VV +L+DR A+V D DG TPL A G D+
Sbjct: 558 DVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGH--VDVV 615
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
LLL GAD + DN G TPL AA ++ V LL +G V + G + LS
Sbjct: 616 DLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLS 670
Score = 118 bits (284), Expect = 8e-26
Identities = 105/324 (32%), Positives = 151/324 (46%), Gaps = 36/324 (11%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT +L A +G + ++ LL G D +D GRT L ++ G+ E V+ LLD G N
Sbjct: 633 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDEN 692
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKE 203
D + TPLH AA + LI GA N +D R P A + V+
Sbjct: 693 HRD---DAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQI 749
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LLE + D L VAA G +LL + GADV G+ T L++ A +
Sbjct: 750 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPT-LYILALEN 808
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL- 322
A L++GA+++ + G+T LH++ +E+V++L+ ADV A D + R+ L
Sbjct: 809 QLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQ 868
Query: 323 ----------------HGAIV-----RGARA-C--------DIARLLLSAGADPNAADNF 352
HGA+V +GA A C D+ ++LL GADPN AD F
Sbjct: 869 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 928
Query: 353 GYTPLHIAALNEFSACVLLLLDYG 376
G T + +AA N S + LL YG
Sbjct: 929 GRTAMRVAAKNGHSQIIKLLEKYG 952
Score = 111 bits (266), Expect = 1e-23
Identities = 97/292 (33%), Positives = 133/292 (45%), Gaps = 10/292 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G + DD RT + + E+ ++ LLD+GA N DS+ T L AA
Sbjct: 351 LVKAGAHVNSEDD--RTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTL---LANAAY 405
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ SL V +L++ GAD+ +PL A +VV L+ GA + T
Sbjct: 406 SGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTA 465
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L AA G LL AG V A + TAL AA GH + LL HGA ++
Sbjct: 466 LRSAAWGGHTEVVSALLYAGVKVDCADADSR-TALRAAAWGGHEDIVLNLLQHGAEVNKA 524
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA---IVRGARACDIARL 338
+ G+T L A E+VE L+D A+V +D DGRT L A + + L
Sbjct: 525 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSL 584
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
L+ GA+ + D G TPL +AA V LLL+ G DV N G + L
Sbjct: 585 LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPL 636
Score = 105 bits (251), Expect = 8e-22
Identities = 97/311 (31%), Positives = 140/311 (45%), Gaps = 10/311 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G ++ L+ G D + D G T L L+ G + V L+ GA+ N
Sbjct: 397 RTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANIN 456
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKE 203
D + T L AA V L+ G V+ +D R+ L A ++V
Sbjct: 457 HTD---QDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLN 513
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT----ALHLA 259
LL+ GA + T L AA +G + LL+ GA+V G+ AL +
Sbjct: 514 LLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 573
Query: 260 AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR 319
A GHA LL+D GA +D + G TPL +A ++VV++L++ ADV D +GR
Sbjct: 574 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 633
Query: 320 TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
TPL A G + LL GA ++ D+ G T L IA+ V LLD G D
Sbjct: 634 TPLLAAASMG--HASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE 691
Query: 380 TLRTNGGVSAL 390
R + G + L
Sbjct: 692 NHRDDAGWTPL 702
Score = 101 bits (242), Expect = 9e-21
Identities = 81/274 (29%), Positives = 132/274 (48%), Gaps = 9/274 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + A + G ++ L++ G +E+D+ GR L+ G +CV++LL++ ++
Sbjct: 700 TPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI-- 757
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKEL 204
D L AA V++L +HGADVN +D P L+ L + + +
Sbjct: 758 -DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYF 816
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
LE GA + T LHV+ G ++L+ ADV AA K +AL AA GH
Sbjct: 817 LENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNE-KRSALQSAAWQGH 875
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ +LL++HGA +D +G T L +A ++VV++L++ AD D GRT +
Sbjct: 876 VKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRV 935
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
A G I +LL GA ++ + +P+H
Sbjct: 936 AAKNG--HSQIIKLLEKYGA--SSLNGCSPSPVH 965
Score = 89.4 bits (212), Expect = 4e-17
Identities = 79/235 (33%), Positives = 104/235 (44%), Gaps = 4/235 (1%)
Query: 164 KSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
K +++L+ GA VN+ DR+ + + ++ LL+ GA + T L
Sbjct: 343 KEQEVLQLLVKAGAHVNSE-DDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLA 401
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
AA GS LL++ GAD+ G T L LAA GH + L+ GA+I+ +
Sbjct: 402 NAAYSGSLDVVNLLVSRGADLEIEDAHGH-TPLTLAARQGHTKVVNCLIGCGANINHTDQ 460
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAG 343
G T L A EVV L+ V DAD RT L A G DI LL G
Sbjct: 461 DGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHE--DIVLNLLQHG 518
Query: 344 ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
A+ N ADN G T L AA V LLD+G +V G +ALS VP
Sbjct: 519 AEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 573
Score = 75.8 bits (178), Expect = 5e-13
Identities = 63/197 (31%), Positives = 96/197 (48%), Gaps = 5/197 (2%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+ R A+ A G ++ L G D + D GR L++ L + L++G
Sbjct: 761 GYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENG 820
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPE 199
A+ D+ T LH + + V+VLIA+ ADVNA ++ RS L A +
Sbjct: 821 ANVEASDAEGR---TALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 877
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
VV+ L+E GA D T L +AA G ++LL GAD A G+ TA+ +A
Sbjct: 878 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGR-TAMRVA 936
Query: 260 AEDGHAECARLLLDHGA 276
A++GH++ +LL +GA
Sbjct: 937 AKNGHSQIIKLLEKYGA 953
>BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein.
Length = 1500
Score = 131 bits (317), Expect = 8e-30
Identities = 107/325 (32%), Positives = 147/325 (45%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ LL+ G + D G T L L+ G V++LLD+GA
Sbjct: 1085 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEA 1144
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGAD-VNAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V++L+A GA+ + +SD +PL A ++K L
Sbjct: 1145 --QSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 1202
Query: 205 LEAGA--CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA T +PL +AA G + KLLL+ G+D+ A + + TAL LA
Sbjct: 1203 LNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQ 1262
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G E LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 1263 GRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 1322
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +AA V LL+ G DV
Sbjct: 1323 ALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAA 1382
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + RYL K
Sbjct: 1383 DNRKITPLMAAFRKGHVKVVRYLVK 1407
Score = 131 bits (316), Expect = 1e-29
Identities = 104/309 (33%), Positives = 140/309 (45%), Gaps = 5/309 (1%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A G ++ AC G + KLL G +E + G + L L+C G E ++
Sbjct: 226 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQV 285
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVL 194
LL H N D + TPL AA+ + VK+L+AH ADVNA S + L YA
Sbjct: 286 LL--AMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACA 343
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VVK LLE+GA + TPL A S G +LLL GA + K +
Sbjct: 344 GGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKES 403
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
AL LA GH E R LL+ GA + T L A + +EV +L+D A V
Sbjct: 404 ALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP 463
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+PL A G ++A LL+ GA ++ GYTPL AA V LLL
Sbjct: 464 ADSFESPLTLAACGG--HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 521
Query: 375 YGGDVTLRT 383
G ++ +T
Sbjct: 522 QGANINAQT 530
Score = 112 bits (269), Expect = 5e-24
Identities = 100/309 (32%), Positives = 142/309 (45%), Gaps = 14/309 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 403 SALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 462
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E+ PL AA + +LI GA + ++D +PL A E+V
Sbjct: 463 PADSFES---PLTLAACGGHVELAALLIERGASLEE-VNDEGYTPLMEAAREGHEEMVAL 518
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G L+ AGAD+ G +T L AA++
Sbjct: 519 LLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIEL----GCSTPLMEAAQE 574
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ + GRTPL
Sbjct: 575 GHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPL 634
Query: 323 HGAIVRGARACDIARLLLSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A R C + + L+S GA+ N N +T L +A A V LLL +G D T
Sbjct: 635 MKA-ARAGHVCTV-QFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTH 692
Query: 382 RTNGGVSAL 390
R G + L
Sbjct: 693 RLKDGSTML 701
Score = 106 bits (255), Expect = 2e-22
Identities = 98/307 (31%), Positives = 143/307 (46%), Gaps = 10/307 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL+ G ++ ++ G T L + G E +LLL++GA NT
Sbjct: 336 TALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINT 395
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 396 --HSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 453
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA + G T L AA +GH
Sbjct: 454 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGY-TPLMEAAREGH 512
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA LEV + L+ AD+ + TPL
Sbjct: 513 EEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADI---ELGCSTPLM 569
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G ++ + LL+AGA+ +A G T L A N + +LL G D+ +
Sbjct: 570 EAAQEGH--LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHES 627
Query: 384 NGGVSAL 390
GG + L
Sbjct: 628 EGGRTPL 634
Score = 102 bits (245), Expect = 4e-21
Identities = 96/295 (32%), Positives = 137/295 (46%), Gaps = 12/295 (4%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
+ TA++ AC G + LL G + D+ + L L+ G E LL++ GA
Sbjct: 434 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGA-- 491
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVLSDAPEVV 201
+ + + TPL AA V +L+ GA++NA + + L A EV
Sbjct: 492 -SLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVA 550
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
L++AGA ++ TPL AA G K LL AGA+V A G TAL A E
Sbjct: 551 DFLIKAGA---DIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGD-TALTYACE 606
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG-RT 320
+GH + A +LL GA ++ + G+TPL A A + V+ L+ + A+V A+ T
Sbjct: 607 NGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHT 666
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
L A G A + LLL+ GADP G T L AA ++ V LLDY
Sbjct: 667 VLSLACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 719
Score = 79.4 bits (187), Expect = 4e-14
Identities = 54/151 (35%), Positives = 80/151 (52%), Gaps = 5/151 (3%)
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
D+ A TAL LA GH E + LL+ GA I+ + +G TPL LA A + VVE
Sbjct: 1074 DIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVE 1133
Query: 303 MLVDRCADVRAKDADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAA 361
+L+D AD+ A+ + TPL A G + ++ LLL+ GA+ + YTPL +AA
Sbjct: 1134 ILLDNGADIEAQSERTKDTPLSLACSGGRQ--EVVELLLARGANKEHRNVSDYTPLSLAA 1191
Query: 362 LNEFSACVLLLLDYGGDVTLRTNG--GVSAL 390
+ + +LL+ G ++ RT G+S L
Sbjct: 1192 SGGYVNIIKILLNAGAEINSRTGSKLGISPL 1222
Score = 73.7 bits (173), Expect = 2e-12
Identities = 71/235 (30%), Positives = 106/235 (45%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
A S + V+ L+ G VN + S L A + E+ + LL A + +
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 219 E-TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
+ TPL AA+ G KLLL ADV A G TAL A G+ + ++LL+ GA
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGN-TALTYACAGGYVDVVKVLLESGAS 359
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L++ A + + + + L A +G ++
Sbjct: 360 IEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGH--LEMV 417
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 418 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 472
>AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein.
Length = 2486
Score = 131 bits (317), Expect = 8e-30
Identities = 107/325 (32%), Positives = 147/325 (45%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ LL+ G + D G T L L+ G V++LLD+GA
Sbjct: 968 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLDNGADIEA 1027
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGAD-VNAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V++L+A GA+ + +SD +PL A ++K L
Sbjct: 1028 --QSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 1085
Query: 205 LEAGA--CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA T +PL +AA G + KLLL+ G+D+ A + + TAL LA
Sbjct: 1086 LNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQ 1145
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G E LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 1146 GRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 1205
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +AA V LL+ G DV
Sbjct: 1206 ALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAA 1265
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + RYL K
Sbjct: 1266 DNRKITPLMAAFRKGHVKVVRYLVK 1290
Score = 128 bits (308), Expect = 9e-29
Identities = 103/309 (33%), Positives = 139/309 (44%), Gaps = 5/309 (1%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A G ++ AC G + KLL G +E + G + L L+C G E ++
Sbjct: 110 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQV 169
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVL 194
LL H N D + T L AA+ + VK+L+AH ADVNA S + L YA
Sbjct: 170 LL--AMHANVEDRGIKGDITSLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACA 227
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VVK LLE+GA + TPL A S G +LLL GA + K +
Sbjct: 228 GGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKES 287
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
AL LA GH E R LL+ GA + T L A + +EV +L+D A V
Sbjct: 288 ALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP 347
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+PL A G ++A LL+ GA ++ GYTPL AA V LLL
Sbjct: 348 ADSFESPLTLAACGG--HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 405
Query: 375 YGGDVTLRT 383
G ++ +T
Sbjct: 406 QGANINAQT 414
Score = 112 bits (269), Expect = 5e-24
Identities = 100/309 (32%), Positives = 142/309 (45%), Gaps = 14/309 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 287 SALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 346
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E+ PL AA + +LI GA + ++D +PL A E+V
Sbjct: 347 PADSFES---PLTLAACGGHVELAALLIERGASLEE-VNDEGYTPLMEAAREGHEEMVAL 402
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G L+ AGAD+ G +T L AA++
Sbjct: 403 LLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIEL----GCSTPLMEAAQE 458
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ + GRTPL
Sbjct: 459 GHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPL 518
Query: 323 HGAIVRGARACDIARLLLSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A R C + + L+S GA+ N N +T L +A A V LLL +G D T
Sbjct: 519 MKA-ARAGHVCTV-QFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTH 576
Query: 382 RTNGGVSAL 390
R G + L
Sbjct: 577 RLKDGSTML 585
Score = 106 bits (255), Expect = 2e-22
Identities = 98/307 (31%), Positives = 143/307 (46%), Gaps = 10/307 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL+ G ++ ++ G T L + G E +LLL++GA NT
Sbjct: 220 TALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINT 279
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 280 --HSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 337
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA + G T L AA +GH
Sbjct: 338 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGY-TPLMEAAREGH 396
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA LEV + L+ AD+ + TPL
Sbjct: 397 EEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADI---ELGCSTPLM 453
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G ++ + LL+AGA+ +A G T L A N + +LL G D+ +
Sbjct: 454 EAAQEGH--LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHES 511
Query: 384 NGGVSAL 390
GG + L
Sbjct: 512 EGGRTPL 518
Score = 102 bits (245), Expect = 4e-21
Identities = 96/295 (32%), Positives = 137/295 (46%), Gaps = 12/295 (4%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
+ TA++ AC G + LL G + D+ + L L+ G E LL++ GA
Sbjct: 318 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGA-- 375
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVLSDAPEVV 201
+ + + TPL AA V +L+ GA++NA + + L A EV
Sbjct: 376 -SLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVA 434
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
L++AGA ++ TPL AA G K LL AGA+V A G TAL A E
Sbjct: 435 DFLIKAGA---DIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGD-TALTYACE 490
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG-RT 320
+GH + A +LL GA ++ + G+TPL A A + V+ L+ + A+V A+ T
Sbjct: 491 NGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHT 550
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
L A G A + LLL+ GADP G T L AA ++ V LLDY
Sbjct: 551 VLSLACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 603
Score = 79.4 bits (187), Expect = 4e-14
Identities = 54/151 (35%), Positives = 80/151 (52%), Gaps = 5/151 (3%)
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
D+ A TAL LA GH E + LL+ GA I+ + +G TPL LA A + VVE
Sbjct: 957 DIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVE 1016
Query: 303 MLVDRCADVRAKDADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAA 361
+L+D AD+ A+ + TPL A G + ++ LLL+ GA+ + YTPL +AA
Sbjct: 1017 ILLDNGADIEAQSERTKDTPLSLACSGGRQ--EVVELLLARGANKEHRNVSDYTPLSLAA 1074
Query: 362 LNEFSACVLLLLDYGGDVTLRTNG--GVSAL 390
+ + +LL+ G ++ RT G+S L
Sbjct: 1075 SGGYVNIIKILLNAGAEINSRTGSKLGISPL 1105
Score = 70.5 bits (165), Expect = 2e-11
Identities = 70/235 (29%), Positives = 105/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
A S + V+ L+ G VN + S L A + E+ + LL A + +
Sbjct: 125 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 184
Query: 219 E-TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
+ T L AA+ G KLLL ADV A G TAL A G+ + ++LL+ GA
Sbjct: 185 DITSLMAAANGGHVKIVKLLLAHKADVNAQSSTGN-TALTYACAGGYVDVVKVLLESGAS 243
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L++ A + + + + L A +G ++
Sbjct: 244 IEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGH--LEMV 301
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 302 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 356
>BC043394-1|AAH43394.1| 751|Homo sapiens ANKRD17 protein protein.
Length = 751
Score = 131 bits (316), Expect = 1e-29
Identities = 104/309 (33%), Positives = 140/309 (45%), Gaps = 5/309 (1%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A G ++ AC G + KLL G +E + G + L L+C G E ++
Sbjct: 226 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQV 285
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVL 194
LL H N D + TPL AA+ + VK+L+AH ADVNA S + L YA
Sbjct: 286 LL--AMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACA 343
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VVK LLE+GA + TPL A S G +LLL GA + K +
Sbjct: 344 GGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKES 403
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
AL LA GH E R LL+ GA + T L A + +EV +L+D A V
Sbjct: 404 ALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP 463
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+PL A G ++A LL+ GA ++ GYTPL AA V LLL
Sbjct: 464 ADSFESPLTLAACGG--HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 521
Query: 375 YGGDVTLRT 383
G ++ +T
Sbjct: 522 QGANINAQT 530
Score = 105 bits (252), Expect = 6e-22
Identities = 102/327 (31%), Positives = 150/327 (45%), Gaps = 13/327 (3%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
+ TA++ AC G + LL G + D+ + L L+ G E LL++ GA
Sbjct: 434 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGA-- 491
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVLSDAPEVV 201
+ + + TPL AA V +L+ GA++NA + + L A EV
Sbjct: 492 -SLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVA 550
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
L++AGA ++ TPL AA G K LL AGA+V A G TAL A E
Sbjct: 551 DFLIKAGA---DIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGD-TALTYACE 606
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG-RT 320
+GH + A +LL GA ++ + G+TPL A A + V+ L+ + A+V A+ T
Sbjct: 607 NGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHT 666
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
L A G A + LLL+ GADP G T L AA ++ V LLDY ++
Sbjct: 667 VLSLACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDYPNNLL 724
Query: 381 LRTNGGVSALSFIVRRVPD-VIPRYLC 406
V+ L+ + D + PR +C
Sbjct: 725 SAPPPDVTQLTPPSHDLTDNIFPRLVC 751
Score = 91.9 bits (218), Expect = 8e-18
Identities = 89/266 (33%), Positives = 115/266 (43%), Gaps = 9/266 (3%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ L L+C G E V+ LL+ GA + T+ T L A + ++L+ GA
Sbjct: 403 SALTLACYKGHLEMVRFLLEAGADQ---EHKTDEMHTALMEACMDGHVEVARLLLDSGAQ 459
Query: 179 VNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
VN S SPL A E+ L+E GA + TPL AA G LL
Sbjct: 460 VNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 519
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L GA++ A + TAL LA G E A L+ GA I+ TPL A
Sbjct: 520 LGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIE---LGCSTPLMEAAQEGH 576
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
LE+V+ L+ A+V A A G T L A G D+A +LL AGAD G TPL
Sbjct: 577 LELVKYLLAAGANVHATTATGDTALTYACENG--HTDVADVLLQAGADLEHESEGGRTPL 634
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRT 383
AA V L+ G +V T
Sbjct: 635 MKAARAGHVCTVQFLISKGANVNRTT 660
Score = 73.7 bits (173), Expect = 2e-12
Identities = 71/235 (30%), Positives = 106/235 (45%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
A S + V+ L+ G VN + S L A + E+ + LL A + +
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 219 E-TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
+ TPL AA+ G KLLL ADV A G TAL A G+ + ++LL+ GA
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGN-TALTYACAGGYVDVVKVLLESGAS 359
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L++ A + + + + L A +G ++
Sbjct: 360 IEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGH--LEMV 417
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 418 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 472
>BC007747-1|AAH07747.2| 830|Homo sapiens ANKRD17 protein protein.
Length = 830
Score = 131 bits (316), Expect = 1e-29
Identities = 104/309 (33%), Positives = 140/309 (45%), Gaps = 5/309 (1%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A G ++ AC G + KLL G +E + G + L L+C G E ++
Sbjct: 46 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQV 105
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVL 194
LL H N D + TPL AA+ + VK+L+AH ADVNA S + L YA
Sbjct: 106 LL--AMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACA 163
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VVK LLE+GA + TPL A S G +LLL GA + K +
Sbjct: 164 GGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKES 223
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
AL LA GH E R LL+ GA + T L A + +EV +L+D A V
Sbjct: 224 ALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP 283
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+PL A G ++A LL+ GA ++ GYTPL AA V LLL
Sbjct: 284 ADSFESPLTLAACGG--HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 341
Query: 375 YGGDVTLRT 383
G ++ +T
Sbjct: 342 QGANINAQT 350
Score = 112 bits (269), Expect = 5e-24
Identities = 100/309 (32%), Positives = 142/309 (45%), Gaps = 14/309 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 223 SALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 282
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E+ PL AA + +LI GA + ++D +PL A E+V
Sbjct: 283 PADSFES---PLTLAACGGHVELAALLIERGASLEE-VNDEGYTPLMEAAREGHEEMVAL 338
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G L+ AGAD+ G +T L AA++
Sbjct: 339 LLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIEL----GCSTPLMEAAQE 394
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ + GRTPL
Sbjct: 395 GHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPL 454
Query: 323 HGAIVRGARACDIARLLLSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A R C + + L+S GA+ N N +T L +A A V LLL +G D T
Sbjct: 455 MKA-ARAGHVCTV-QFLISKGANVNRTTANNDHTVLSLACAGGHLAVVELLLAHGADPTH 512
Query: 382 RTNGGVSAL 390
R G + L
Sbjct: 513 RLKDGSTML 521
Score = 106 bits (255), Expect = 2e-22
Identities = 98/307 (31%), Positives = 143/307 (46%), Gaps = 10/307 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL+ G ++ ++ G T L + G E +LLL++GA NT
Sbjct: 156 TALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINT 215
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 216 --HSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 273
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA + G T L AA +GH
Sbjct: 274 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGY-TPLMEAAREGH 332
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA LEV + L+ AD+ + TPL
Sbjct: 333 EEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADI---ELGCSTPLM 389
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G ++ + LL+AGA+ +A G T L A N + +LL G D+ +
Sbjct: 390 EAAQEGH--LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHES 447
Query: 384 NGGVSAL 390
GG + L
Sbjct: 448 EGGRTPL 454
Score = 102 bits (245), Expect = 4e-21
Identities = 96/295 (32%), Positives = 137/295 (46%), Gaps = 12/295 (4%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
+ TA++ AC G + LL G + D+ + L L+ G E LL++ GA
Sbjct: 254 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGA-- 311
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVLSDAPEVV 201
+ + + TPL AA V +L+ GA++NA + + L A EV
Sbjct: 312 -SLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVA 370
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
L++AGA ++ TPL AA G K LL AGA+V A G TAL A E
Sbjct: 371 DFLIKAGA---DIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGD-TALTYACE 426
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG-RT 320
+GH + A +LL GA ++ + G+TPL A A + V+ L+ + A+V A+ T
Sbjct: 427 NGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGANVNRTTANNDHT 486
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
L A G A + LLL+ GADP G T L AA ++ V LLDY
Sbjct: 487 VLSLACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAAKGGHTSVVCYLLDY 539
Score = 73.7 bits (173), Expect = 2e-12
Identities = 71/235 (30%), Positives = 106/235 (45%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
A S + V+ L+ G VN + S L A + E+ + LL A + +
Sbjct: 61 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 120
Query: 219 E-TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
+ TPL AA+ G KLLL ADV A G TAL A G+ + ++LL+ GA
Sbjct: 121 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGN-TALTYACAGGYVDVVKVLLESGAS 179
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L++ A + + + + L A +G ++
Sbjct: 180 IEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGH--LEMV 237
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 238 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 292
>AF308285-1|AAG48253.1| 1188|Homo sapiens serologically defined
breast cancer antigen NY-BR-16 protein.
Length = 1188
Score = 131 bits (316), Expect = 1e-29
Identities = 104/309 (33%), Positives = 140/309 (45%), Gaps = 5/309 (1%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S A G ++ AC G + KLL G +E + G + L L+C G E ++
Sbjct: 226 STANAGQSDNRSLAEACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQV 285
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVL 194
LL H N D + TPL AA+ + VK+L+AH ADVNA S + L YA
Sbjct: 286 LL--AMHANVEDRGIKGDITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACA 343
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+VVK LLE+GA + TPL A S G +LLL GA + K +
Sbjct: 344 GGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKES 403
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
AL LA GH E R LL+ GA + T L A + +EV +L+D A V
Sbjct: 404 ALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP 463
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
+PL A G ++A LL+ GA ++ GYTPL AA V LLL
Sbjct: 464 ADSFESPLTLAACGG--HVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALLLG 521
Query: 375 YGGDVTLRT 383
G ++ +T
Sbjct: 522 QGANINAQT 530
Score = 106 bits (255), Expect = 2e-22
Identities = 98/307 (31%), Positives = 143/307 (46%), Gaps = 10/307 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL+ G ++ ++ G T L + G E +LLL++GA NT
Sbjct: 336 TALTYACAGGYVDVVKVLLESGASIEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINT 395
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 396 --HSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 453
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA + G T L AA +GH
Sbjct: 454 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGY-TPLMEAAREGH 512
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA LEV + L+ AD+ + TPL
Sbjct: 513 EEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADI---ELGCSTPLM 569
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G ++ + LL+AGA+ +A G T L A N + +LL G D+ +
Sbjct: 570 EAAQEGH--LELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHES 627
Query: 384 NGGVSAL 390
GG + L
Sbjct: 628 EGGRTPL 634
Score = 95.9 bits (228), Expect = 5e-19
Identities = 90/294 (30%), Positives = 132/294 (44%), Gaps = 10/294 (3%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
+ TA++ AC G + LL G + D+ + L L+ G E LL++ GA
Sbjct: 434 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGA-- 491
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVLSDAPEVV 201
+ + + TPL AA V +L+ GA++NA + + L A EV
Sbjct: 492 -SLEEVNDEGYTPLMEAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVA 550
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
L++AGA ++ TPL AA G K LL AGA+V A G TAL A E
Sbjct: 551 DFLIKAGA---DIELGCSTPLMEAAQEGHLELVKYLLAAGANVHATTATGD-TALTYACE 606
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+GH + A +LL GA ++ + G+TPL A A + V+ L+ + A+ ++ T
Sbjct: 607 NGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHVCTVQFLISKGAECESEPQLIMTI 666
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
L G + LLL+ GADP G T L A ++ LLDY
Sbjct: 667 LSALACAGGHLA-VVELLLAHGADPTHRLKDGSTMLIEAPKGGHTSVGCYLLDY 719
Score = 89.8 bits (213), Expect = 3e-17
Identities = 87/261 (33%), Positives = 113/261 (43%), Gaps = 9/261 (3%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ L L+C G E V+ LL+ GA + T+ T L A + ++L+ GA
Sbjct: 403 SALTLACYKGHLEMVRFLLEAGADQ---EHKTDEMHTALMEACMDGHVEVARLLLDSGAQ 459
Query: 179 VNAGL-SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
VN S SPL A E+ L+E GA + TPL AA G LL
Sbjct: 460 VNMPADSFESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLMEAAREGHEEMVALL 519
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L GA++ A + TAL LA G E A L+ GA I+ TPL A
Sbjct: 520 LGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIE---LGCSTPLMEAAQEGH 576
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
LE+V+ L+ A+V A A G T L A G D+A +LL AGAD G TPL
Sbjct: 577 LELVKYLLAAGANVHATTATGDTALTYACENG--HTDVADVLLQAGADLEHESEGGRTPL 634
Query: 358 HIAALNEFSACVLLLLDYGGD 378
AA V L+ G +
Sbjct: 635 MKAARAGHVCTVQFLISKGAE 655
Score = 73.7 bits (173), Expect = 2e-12
Identities = 71/235 (30%), Positives = 106/235 (45%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
A S + V+ L+ G VN + S L A + E+ + LL A + +
Sbjct: 241 ACSEGDVNAVRKLLIEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGIKG 300
Query: 219 E-TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
+ TPL AA+ G KLLL ADV A G TAL A G+ + ++LL+ GA
Sbjct: 301 DITPLMAAANGGHVKIVKLLLAHKADVNAQSSTGN-TALTYACAGGYVDVVKVLLESGAS 359
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L++ A + + + + L A +G ++
Sbjct: 360 IEDHNENGHTPLMEAGSAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGH--LEMV 417
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 418 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 472
Score = 37.9 bits (84), Expect = 0.13
Identities = 22/55 (40%), Positives = 29/55 (52%)
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
D+ A TAL LA GH E + LL+ GA I+ + +G TPL LA + S
Sbjct: 1074 DIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATSWS 1128
>AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein.
Length = 1089
Score = 131 bits (316), Expect = 1e-29
Identities = 107/337 (31%), Positives = 149/337 (44%), Gaps = 6/337 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A W G ++ LL+ G + ++ D+ GRT L + +G E V+ LLDHGA N
Sbjct: 305 RTVLRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVN 364
Query: 145 --TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVV 201
D T L AS + V +LI GA+V+ D +PL A +VV
Sbjct: 365 HEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV 424
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
LLE GA D TPL AAS+G AS LL GA V + G+ T L +A+
Sbjct: 425 DLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGR-TVLSIASA 483
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
G+ E R LLD G + + G TPLH+A + E L+++ A D DGR P
Sbjct: 484 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIP 543
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A G C ++LL ++ + G L +AAL V LL +G DV
Sbjct: 544 FILASQEGHYDC--VQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNC 601
Query: 382 RTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+ G L + + Y + V S+ E
Sbjct: 602 KDADGRPTLYILALENQLTMAEYFLENGANVEASDAE 638
Score = 123 bits (297), Expect = 2e-27
Identities = 94/297 (31%), Positives = 145/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G + ++ L+ G + D D G T L ++ G + V LLL+ GA + D++ T
Sbjct: 386 GHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRT-- 443
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT 213
PL AAS + V L+ GA V++ S+ R+ L A EVV+ LL+ G +
Sbjct: 444 -PLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH 502
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPLH+AA G + L+ GA G+ + LA+++GH +C ++LL+
Sbjct: 503 RDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFI-LASQEGHYDCVQILLE 561
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+ ++ID + G+ L +A L ++VE+L ADV KDADGR L+ I+
Sbjct: 562 NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLY--ILALENQL 619
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A L GA+ A+D G T LH++ V +L+ Y DV N SAL
Sbjct: 620 TMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSAL 676
Score = 122 bits (295), Expect = 4e-27
Identities = 107/295 (36%), Positives = 134/295 (45%), Gaps = 12/295 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G ++ D GRT L + GS + V LL+ GA D+ T PL AA
Sbjct: 191 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHT---PLTLAAR 247
Query: 163 AKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V LI GA++N D + L A EVV LL AG D + T
Sbjct: 248 QGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTV 307
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L AA G LL GA+V A G+ TAL AA GH E LLDHGA ++
Sbjct: 308 LRAAAWGGHEDIVLNLLQHGAEVNKADNEGR-TALIAAAYMGHREIVEHLLDHGAEVNHE 366
Query: 282 NFRGQTPLHLATLAQSLE-----VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
+ G+T L +A L VV +L+DR A+V D DG TPL A G D+
Sbjct: 367 DVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGH--VDVV 424
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
LLL GAD + DN G TPL AA ++ V LL +G V + G + LS
Sbjct: 425 DLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLS 479
Score = 118 bits (284), Expect = 8e-26
Identities = 105/324 (32%), Positives = 151/324 (46%), Gaps = 36/324 (11%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT +L A +G + ++ LL G D +D GRT L ++ G+ E V+ LLD G N
Sbjct: 442 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDEN 501
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKE 203
D + TPLH AA + LI GA N +D R P A + V+
Sbjct: 502 HRD---DAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQI 558
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LLE + D L VAA G +LL + GADV G+ T L++ A +
Sbjct: 559 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPT-LYILALEN 617
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL- 322
A L++GA+++ + G+T LH++ +E+V++L+ ADV A D + R+ L
Sbjct: 618 QLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQ 677
Query: 323 ----------------HGAIV-----RGARA-C--------DIARLLLSAGADPNAADNF 352
HGA+V +GA A C D+ ++LL GADPN AD F
Sbjct: 678 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 737
Query: 353 GYTPLHIAALNEFSACVLLLLDYG 376
G T + +AA N S + LL YG
Sbjct: 738 GRTAMRVAAKNGHSQIIKLLEKYG 761
Score = 109 bits (262), Expect = 4e-23
Identities = 96/292 (32%), Positives = 132/292 (45%), Gaps = 10/292 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G + DD RT + + E+ ++ LLD+GA N DS+ T L AA
Sbjct: 160 LVKAGAHVNSEDD--RTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTL---LANAAY 214
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ SL V +L++ GAD+ +PL A +VV L+ GA + T
Sbjct: 215 SGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTA 274
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L AA G LL AG V A + T L AA GH + LL HGA ++
Sbjct: 275 LRSAAWGGHTEVVSALLYAGVKVDCADADSR-TVLRAAAWGGHEDIVLNLLQHGAEVNKA 333
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA---IVRGARACDIARL 338
+ G+T L A E+VE L+D A+V +D DGRT L A + + L
Sbjct: 334 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSL 393
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
L+ GA+ + D G TPL +AA V LLL+ G DV N G + L
Sbjct: 394 LIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPL 445
Score = 104 bits (250), Expect = 1e-21
Identities = 97/311 (31%), Positives = 140/311 (45%), Gaps = 10/311 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G ++ L+ G D + D G T L L+ G + V L+ GA+ N
Sbjct: 206 RTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANIN 265
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKE 203
D + T L AA V L+ G V+ +D R+ L A ++V
Sbjct: 266 HTD---QDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHEDIVLN 322
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT----ALHLA 259
LL+ GA + T L AA +G + LL+ GA+V G+ AL +
Sbjct: 323 LLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 382
Query: 260 AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR 319
A GHA LL+D GA +D + G TPL +A ++VV++L++ ADV D +GR
Sbjct: 383 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGR 442
Query: 320 TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
TPL A G + LL GA ++ D+ G T L IA+ V LLD G D
Sbjct: 443 TPLLAAASMG--HASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDE 500
Query: 380 TLRTNGGVSAL 390
R + G + L
Sbjct: 501 NHRDDAGWTPL 511
Score = 101 bits (242), Expect = 9e-21
Identities = 81/274 (29%), Positives = 132/274 (48%), Gaps = 9/274 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + A + G ++ L++ G +E+D+ GR L+ G +CV++LL++ ++
Sbjct: 509 TPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI-- 566
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKEL 204
D L AA V++L +HGADVN +D P L+ L + + +
Sbjct: 567 -DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYF 625
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
LE GA + T LHV+ G ++L+ ADV AA K +AL AA GH
Sbjct: 626 LENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNE-KRSALQSAAWQGH 684
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ +LL++HGA +D +G T L +A ++VV++L++ AD D GRT +
Sbjct: 685 VKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRV 744
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
A G I +LL GA ++ + +P+H
Sbjct: 745 AAKNG--HSQIIKLLEKYGA--SSLNGCSPSPVH 774
Score = 89.0 bits (211), Expect = 5e-17
Identities = 79/235 (33%), Positives = 104/235 (44%), Gaps = 4/235 (1%)
Query: 164 KSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
K +++L+ GA VN+ DR+ + + ++ LL+ GA + T L
Sbjct: 152 KEQEVLQLLVKAGAHVNSE-DDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLA 210
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
AA GS LL++ GAD+ G T L LAA GH + L+ GA+I+ +
Sbjct: 211 NAAYSGSLDVVNLLVSRGADLEIEDAHGH-TPLTLAARQGHTKVVNCLIGCGANINHTDQ 269
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAG 343
G T L A EVV L+ V DAD RT L A G DI LL G
Sbjct: 270 DGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHE--DIVLNLLQHG 327
Query: 344 ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
A+ N ADN G T L AA V LLD+G +V G +ALS VP
Sbjct: 328 AEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVP 382
Score = 75.8 bits (178), Expect = 5e-13
Identities = 63/197 (31%), Positives = 96/197 (48%), Gaps = 5/197 (2%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+ R A+ A G ++ L G D + D GR L++ L + L++G
Sbjct: 570 GYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENG 629
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPE 199
A+ D+ T LH + + V+VLIA+ ADVNA ++ RS L A +
Sbjct: 630 ANVEASDAEGR---TALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 686
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
VV+ L+E GA D T L +AA G ++LL GAD A G+ TA+ +A
Sbjct: 687 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGR-TAMRVA 745
Query: 260 AEDGHAECARLLLDHGA 276
A++GH++ +LL +GA
Sbjct: 746 AKNGHSQIIKLLEKYGA 762
>AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22206 fis, clone HRC01431. ).
Length = 460
Score = 128 bits (310), Expect = 5e-29
Identities = 106/325 (32%), Positives = 146/325 (44%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ LL+ G + D G T L L+ G V++LL +GA
Sbjct: 49 TALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVEILLGNGADIEA 108
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGAD-VNAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V++L+A GA+ + +SD +PL A ++K L
Sbjct: 109 --QSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 166
Query: 205 LEAGA--CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA T +PL +AA G + KLLL+ G+D+ A + + TAL LA
Sbjct: 167 LNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTALTLACFQ 226
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G E LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 227 GRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 286
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +AA V LL+ G DV
Sbjct: 287 ALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANGGHLDVVQLLVQAGADVDAA 346
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + RYL K
Sbjct: 347 DNRKITPLMAAFRKGHVKVVRYLVK 371
Score = 119 bits (286), Expect = 4e-26
Identities = 97/274 (35%), Positives = 137/274 (50%), Gaps = 11/274 (4%)
Query: 59 ISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGR 118
+ +L+GNG I+ SE T + AC G+ ++ LL G + + + +
Sbjct: 96 VEILLGNG---ADIEAQSERTKD----TPLSLACSGGRQEVVELLLARGANKEHRNVSDY 148
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T L L+ G +K+LL+ GA N+ S + +PL AA A VK+L+ G+D
Sbjct: 149 TPLSLAASGGYVNIIKILLNAGAEINSRTGS-KLGISPLMLAAMNGHTAAVKLLLDMGSD 207
Query: 179 VNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
+NA + + L A EVV LL+ A + TPL AAS G A ++
Sbjct: 208 INAQIETNRNTALTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRV 267
Query: 237 LLNAGADVRAAMGPG-KATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LL+ GADV A P + TAL +AA+ GH + LL+ GAHID N +G TPL LA
Sbjct: 268 LLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANG 327
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
L+VV++LV ADV A D TPL A +G
Sbjct: 328 GHLDVVQLLVQAGADVDAADNRKITPLMAAFRKG 361
Score = 76.6 bits (180), Expect = 3e-13
Identities = 53/151 (35%), Positives = 79/151 (52%), Gaps = 5/151 (3%)
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
D+ A TAL LA GH E + LL+ GA I+ + +G TPL LA A + VVE
Sbjct: 38 DIDAQTESNHDTALTLACAGGHEELVQTLLERGASIEHRDKKGFTPLILAATAGHVGVVE 97
Query: 303 MLVDRCADVRAKDADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAA 361
+L+ AD+ A+ + TPL A G + ++ LLL+ GA+ + YTPL +AA
Sbjct: 98 ILLGNGADIEAQSERTKDTPLSLACSGGRQ--EVVELLLARGANKEHRNVSDYTPLSLAA 155
Query: 362 LNEFSACVLLLLDYGGDVTLRTNG--GVSAL 390
+ + +LL+ G ++ RT G+S L
Sbjct: 156 SGGYVNIIKILLNAGAEINSRTGSKLGISPL 186
>BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein.
Length = 306
Score = 127 bits (306), Expect = 2e-28
Identities = 90/278 (32%), Positives = 135/278 (48%), Gaps = 8/278 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K D + D +T LH++ + +C ++++ + N D T LH AA
Sbjct: 32 LIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTA---LHHAAL 88
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V +L+A GA++NA DR LH+A +VV L+ GA TP
Sbjct: 89 NGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTP 148
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH AAS G + K LLN G ++ G TALH+A +G L+D+GA+++ P
Sbjct: 149 LHAAASNGQINVVKHLLNLGVEIDEINVYGN-TALHIACYNGQDAVVNELIDYGANVNQP 207
Query: 282 NFRGQTPLHLATLA-QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N G TPLH A + +E+LV+ ADV + DG++PLH V G ++ L+
Sbjct: 208 NNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTR--SQTLI 265
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
G + + D G TPLH+AA + L+ G D
Sbjct: 266 QNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 303
Score = 126 bits (305), Expect = 2e-28
Identities = 83/238 (34%), Positives = 124/238 (52%), Gaps = 5/238 (2%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT 213
TPLH A +++S V+VLI H ADVNA + ++PLH A + A + + ++ + +
Sbjct: 15 TPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNV 74
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
T LH AA G LLL GA++ A ALH AA GH + LL++
Sbjct: 75 SDRGGRTALHHAALNGHVEMVNLLLAKGANIN-AFDKKDRRALHWAAYMGHLDVVALLIN 133
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
HGA + + +G TPLH A + VV+ L++ ++ + G T LH A G A
Sbjct: 134 HGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDA- 192
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSA-CVLLLLDYGGDVTLRTNGGVSAL 390
+ L+ GA+ N +N G+TPLH AA + A C+ LL++ G DV +++ G S L
Sbjct: 193 -VVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPL 249
Score = 126 bits (303), Expect = 4e-28
Identities = 95/283 (33%), Positives = 135/283 (47%), Gaps = 6/283 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D+ T LH + SEE V++L+ H A N D + +T PLH AA+ K++ C +V+I
Sbjct: 10 DNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQT---PLHVAAANKAVKCAEVII 66
Query: 174 AHGADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
+ VN R+ LH+A L+ E+V LL GA + LH AA +G
Sbjct: 67 PLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLD 126
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
LL+N GA+V G T LH AA +G + LL+ G ID N G T LH+A
Sbjct: 127 VVALLINHGAEVTCKDKKGY-TPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIA 185
Query: 293 TLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNF 352
VV L+D A+V + +G TPLH A A + LL++ GAD N
Sbjct: 186 CYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCL-ELLVNNGADVNIQSKD 244
Query: 353 GYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
G +PLH+ A++ L+ GG++ G + L R
Sbjct: 245 GKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAAR 287
Score = 119 bits (287), Expect = 3e-26
Identities = 79/218 (36%), Positives = 118/218 (54%), Gaps = 4/218 (1%)
Query: 176 GADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GA VNA + +PLH AV S + E V+ L++ A + +TPLHVAA+ + C
Sbjct: 3 GARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCA 62
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL 294
++++ + V + G+ TALH AA +GH E LLL GA+I+ + + + LH A
Sbjct: 63 EVIIPLLSSVNVSDRGGR-TALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAY 121
Query: 295 AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGY 354
L+VV +L++ A+V KD G TPLH A G ++ + LL+ G + + + +G
Sbjct: 122 MGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQ--INVVKHLLNLGVEIDEINVYGN 179
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
T LHIA N A V L+DYG +V N G + L F
Sbjct: 180 TALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHF 217
Score = 103 bits (248), Expect = 2e-21
Identities = 77/230 (33%), Positives = 112/230 (48%), Gaps = 6/230 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G RTA+ A G ++ LL G + + D R LH + +G + V LL++HGA
Sbjct: 78 GGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 137
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVV 201
D + TPLH AAS + VK L+ G +++ + + LH A + VV
Sbjct: 138 VTCKD---KKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVV 194
Query: 202 KELLEAGACPDTPQVFTETPLH-VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAA 260
EL++ GA + P TPLH AAS A C +LL+N GADV GK + LH+ A
Sbjct: 195 NELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGK-SPLHMTA 253
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCAD 310
G ++ L+ +G ID + G TPLH+A ++ L+ AD
Sbjct: 254 VHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGAD 303
Score = 32.7 bits (71), Expect = 4.9
Identities = 16/41 (39%), Positives = 21/41 (51%)
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
+GA NA DN TPLH A + V +L+ + DV R
Sbjct: 2 SGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNAR 42
>AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein
protein.
Length = 520
Score = 124 bits (300), Expect = 9e-28
Identities = 111/348 (31%), Positives = 160/348 (45%), Gaps = 22/348 (6%)
Query: 55 YSEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELD 114
+SE + +LIGN Q A + + G G +T ++ + G + ++ LL G + D D
Sbjct: 96 HSECLRLLIGNAEP----QNAVDIQDGNG-QTPLMLSVLNGHTDCVYSLLNKGANVDAKD 150
Query: 115 DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIA 174
GRT LH + G EECV LL HGA DS TP+H +A+ + + L+
Sbjct: 151 KWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGR---TPIHLSAACGHIGVLGALLQ 207
Query: 175 HGA--DVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLG 229
A D N +D + LH+A + V+ LLE T + +PLH A
Sbjct: 208 SAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKT-EGNAFSPLHCAVIND 266
Query: 230 SASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTP 288
+ ++L++ GA + A T LH AA H EC +LLL H A ++ + G+TP
Sbjct: 267 NEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTP 326
Query: 289 LHLATLAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADP- 346
L +A VEMLV A++ +D T LH A +G A L+L D
Sbjct: 327 LMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETS--ALLILEKITDRN 384
Query: 347 --NAADNFGYTPLHIAALNEFSACVLLLLDYGGDV-TLRTNGGVSALS 391
NA + TPLH+AA N + V LL G V + NG AL+
Sbjct: 385 LINATNAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALA 432
Score = 111 bits (267), Expect = 9e-24
Identities = 89/280 (31%), Positives = 128/280 (45%), Gaps = 10/280 (3%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
RT +H + G EC++LL+ + N D TPL + CV L+ GA
Sbjct: 85 RTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGA 144
Query: 178 DVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
+V+A R+ LH ++ E V LL+ GA TP+H++A+ G
Sbjct: 145 NVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 204
Query: 237 LLNAGA--DVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT 293
LL + A D A TALH A +GH C LLL+ +PLH A
Sbjct: 205 LLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEV-FQKTEGNAFSPLHCAV 263
Query: 294 LAQSLEVVEMLVDR--CADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
+ + EML+D + V A D+ GRTPLH A C +LLLS A N+ D+
Sbjct: 264 INDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVEC--LQLLLSHNAQVNSVDS 321
Query: 352 FGYTPLHIAALN-EFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL +AA N + + +L+ ++TL+ N +AL
Sbjct: 322 TGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTAL 361
Score = 108 bits (260), Expect = 6e-23
Identities = 82/246 (33%), Positives = 117/246 (47%), Gaps = 10/246 (4%)
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELL 205
DS +PLH AA ++VL+ D++ S R+PL A E V L+
Sbjct: 11 DSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLI 70
Query: 206 EAGACPDTPQ-VFTETPLHVAASLGSASCTKLLL-NAGADVRAAMGPGKA-TALHLAAED 262
GA + TP+H AA+ G + C +LL+ NA + G T L L+ +
Sbjct: 71 NQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLN 130
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH +C LL+ GA++D + G+T LH + E V+ L+ A +D+ GRTP+
Sbjct: 131 GHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPI 190
Query: 323 HGAIVRGARACDIARLLLSAG---ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
H + G + LL SA A+P ADN GYT LH A N CV LLL+ +V
Sbjct: 191 HLSAACGHIGV-LGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQ--EV 247
Query: 380 TLRTNG 385
+T G
Sbjct: 248 FQKTEG 253
Score = 107 bits (258), Expect = 1e-22
Identities = 94/309 (30%), Positives = 140/309 (45%), Gaps = 14/309 (4%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A + G L L++ +D D + +GRT L L+ G ECV +L++ GA D
Sbjct: 24 AAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKDYI- 82
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSD---RSPLHYAVLSDAPEVVKELLE 206
K TP+H AA+ C+++LI + NA + D ++PL +VL+ + V LL
Sbjct: 83 -LKRTPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLN 141
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE 266
GA D + T LH A G C LL GA G+ T +HL+A GH
Sbjct: 142 KGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGR-TPIHLSAACGHIG 200
Query: 267 CARLLLDHGAHID----WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
LL A +D + G T LH A VE+L+++ + + + +PL
Sbjct: 201 VLGALLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQ-EVFQKTEGNAFSPL 259
Query: 323 HGAIVRGARACDIARLLLSAGAD-PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
H A++ L+ + GA NA D+ G TPLH AA + C+ LLL + V
Sbjct: 260 HCAVINDNEGA-AEMLIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNS 318
Query: 382 RTNGGVSAL 390
+ G + L
Sbjct: 319 VDSTGKTPL 327
Score = 62.9 bits (146), Expect = 4e-09
Identities = 55/166 (33%), Positives = 74/166 (44%), Gaps = 12/166 (7%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + EC++LLL H A N+ DS T TPL AA V++L+
Sbjct: 287 DSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDS---TGKTPLMMAAENGQTNTVEMLV 343
Query: 174 AHGADVNAGLSDRSP---LHYAVL----SDAPEVVKELLEAGACPDTPQVFTETPLHVAA 226
+ A L D S LH A + A +++++ + T +TPLHVAA
Sbjct: 344 S-SASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAAL-QTPLHVAA 401
Query: 227 SLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
G + LL GA V A G AL A A+C L+L
Sbjct: 402 RNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALIL 447
>BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 269
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 270 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 329
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 450 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 265 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 324
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 325 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 381
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 382 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 440
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 441 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 501 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 556 ASGANVHATTATGDTALTY 574
Score = 102 bits (244), Expect = 5e-21
Identities = 94/296 (31%), Positives = 138/296 (46%), Gaps = 10/296 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 307 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 366
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 367 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 483
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 484 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 540
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
A G ++ + LL++GA+ +A G T L A N + +LL G D+
Sbjct: 541 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 594
Score = 90.6 bits (215), Expect = 2e-17
Identities = 85/269 (31%), Positives = 123/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD G N E+ L C+A LA V + + +
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 270
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 271 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 330
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 331 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 446
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 447 CGGHVELAALLIERGANLEEVNDEGYTPL 475
Score = 84.6 bits (200), Expect = 1e-15
Identities = 76/242 (31%), Positives = 113/242 (46%), Gaps = 12/242 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 434 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 489
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 545
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ K D +T L
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL-DKQEDMKTIL 604
Query: 323 HG 324
G
Sbjct: 605 EG 606
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 330
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 388
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 389 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 443
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 200 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 260 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 377
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 378 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 409
>BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein.
Length = 581
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 269
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 270 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 329
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 450 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Score = 96.3 bits (229), Expect = 4e-19
Identities = 87/272 (31%), Positives = 129/272 (47%), Gaps = 9/272 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 265 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 324
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 325 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 381
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 382 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 440
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 441 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGAD 345
+ + T L A G ++A L+ AGAD
Sbjct: 501 TEETQETALTLACCGG--FSEVADFLIKAGAD 530
Score = 93.9 bits (223), Expect = 2e-18
Identities = 86/270 (31%), Positives = 125/270 (46%), Gaps = 10/270 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 307 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 366
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 367 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 483
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 484 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 540
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFG 353
A G ++ + LL++G D FG
Sbjct: 541 EASQEG--HLELVKYLLASGQAGGHEDYFG 568
Score = 90.6 bits (215), Expect = 2e-17
Identities = 85/269 (31%), Positives = 123/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD G N E+ L C+A LA V + + +
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 270
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 271 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 330
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 331 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 446
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 447 CGGHVELAALLIERGANLEEVNDEGYTPL 475
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 330
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 388
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 389 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 443
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 200 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 260 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 377
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 378 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 409
Score = 33.5 bits (73), Expect = 2.8
Identities = 53/221 (23%), Positives = 92/221 (41%), Gaps = 15/221 (6%)
Query: 177 ADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
++V + + D+ L VL E+ GA D V ET + A L +A KL
Sbjct: 101 SEVESFILDQEDLDNPVLKTTSEIFLSSTAEGA--DLRTVDPETQARLEALLEAAGIGKL 158
Query: 237 LLNAGADVRAAMGPGK----ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
+ AD +A P +++ A ++ A R+ ++ + + R L A
Sbjct: 159 ---STADGKAFADPEVLRRLTSSVSCALDEAAAALTRMKAENSHNAGQVDTRS---LAEA 212
Query: 293 TLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNF 352
+ V L+D V +G + L + A ++A++LL+ A+ N
Sbjct: 213 CSDGDVNAVRKLLDEGRSVNEHTEEGESLL--CLACSAGYYELAQVLLAMHANVEDRGNK 270
Query: 353 G-YTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
G TPL A+ + V LLL + DV ++ G +AL++
Sbjct: 271 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTY 311
>BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 269
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 270 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 329
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 450 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 265 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 324
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 325 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 381
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 382 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 440
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 441 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 501 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 556 ASGANVHATTATGDTALTY 574
Score = 102 bits (244), Expect = 5e-21
Identities = 94/296 (31%), Positives = 138/296 (46%), Gaps = 10/296 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 307 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 366
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 367 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 483
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 484 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 540
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
A G ++ + LL++GA+ +A G T L A N + +LL G D+
Sbjct: 541 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 594
Score = 90.6 bits (215), Expect = 2e-17
Identities = 85/269 (31%), Positives = 123/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD G N E+ L C+A LA V + + +
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 270
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 271 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 330
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 331 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 446
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 447 CGGHVELAALLIERGANLEEVNDEGYTPL 475
Score = 84.6 bits (200), Expect = 1e-15
Identities = 76/242 (31%), Positives = 113/242 (46%), Gaps = 12/242 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 434 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 489
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 545
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ K D +T L
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL-DKQEDMKTIL 604
Query: 323 HG 324
G
Sbjct: 605 EG 606
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 330
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 388
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 389 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 443
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 200 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 260 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 377
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 378 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 409
>BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein.
Length = 743
Score = 123 bits (297), Expect = 2e-27
Identities = 94/297 (31%), Positives = 145/297 (48%), Gaps = 7/297 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G + ++ L+ G + D D G T L ++ G + V LLL+ GA + D++ T
Sbjct: 40 GHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRT-- 97
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT 213
PL AAS + V L+ GA V++ S+ R+ L A EVV+ LL+ G +
Sbjct: 98 -PLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENH 156
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPLH+AA G + L+ GA G+ + LA+++GH +C ++LL+
Sbjct: 157 RDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFI-LASQEGHYDCVQILLE 215
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+ ++ID + G+ L +A L ++VE+L ADV KDADGR L+ I+
Sbjct: 216 NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLY--ILALENQL 273
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A L GA+ A+D G T LH++ V +L+ Y DV N SAL
Sbjct: 274 TMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSAL 330
Score = 120 bits (289), Expect = 2e-26
Identities = 92/306 (30%), Positives = 149/306 (48%), Gaps = 7/306 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T +L A + G ++ LL+ G D D D+ GRT L + +G V LL GA ++
Sbjct: 64 TPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDS 123
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
DS T L A++ ++ V+ L+ G D N + +PLH A + + L
Sbjct: 124 IDSEGR---TVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 180
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
+E GA + P +A+ G C ++LL +++ G+ AL +AA +GH
Sbjct: 181 IEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGR-NALRVAALEGH 239
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ LL HGA ++ + G+ L++ L L + E ++ A+V A DA+GRT LH
Sbjct: 240 RDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHV 299
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
+ +G ++ ++L++ AD NAADN + L AA V LL+++G V N
Sbjct: 300 SCWQG--HMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCN 357
Query: 385 GGVSAL 390
G +AL
Sbjct: 358 QGATAL 363
Score = 118 bits (284), Expect = 8e-26
Identities = 105/324 (32%), Positives = 151/324 (46%), Gaps = 36/324 (11%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT +L A +G + ++ LL G D +D GRT L ++ G+ E V+ LLD G N
Sbjct: 96 RTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDEN 155
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKE 203
D + TPLH AA + LI GA N +D R P A + V+
Sbjct: 156 HRD---DAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQI 212
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
LLE + D L VAA G +LL + GADV G+ T L++ A +
Sbjct: 213 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPT-LYILALEN 271
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL- 322
A L++GA+++ + G+T LH++ +E+V++L+ ADV A D + R+ L
Sbjct: 272 QLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQ 331
Query: 323 ----------------HGAIV-----RGARA-C--------DIARLLLSAGADPNAADNF 352
HGA+V +GA A C D+ ++LL GADPN AD F
Sbjct: 332 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQF 391
Query: 353 GYTPLHIAALNEFSACVLLLLDYG 376
G T + +AA N S + LL YG
Sbjct: 392 GRTAMRVAAKNGHSQIIKLLEKYG 415
Score = 107 bits (257), Expect = 1e-22
Identities = 94/295 (31%), Positives = 127/295 (43%), Gaps = 6/295 (2%)
Query: 127 VGSEECVKLLLDHGAHPN--TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLS 184
+G E V+ LLDHGA N D T L AS + V +LI GA+V+
Sbjct: 1 MGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDK 60
Query: 185 D-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A +VV LLE GA D TPL AAS+G AS LL GA
Sbjct: 61 DGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAA 120
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V + G+ T L +A+ G+ E R LLD G + + G TPLH+A + E
Sbjct: 121 VDSIDSEGR-TVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEA 179
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+++ A D DGR P A G C ++LL ++ + G L +AAL
Sbjct: 180 LIEQGARTNEIDNDGRIPFILASQEGHYDC--VQILLENKSNIDQRGYDGRNALRVAALE 237
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
V LL +G DV + G L + + Y + V S+ E
Sbjct: 238 GHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAE 292
Score = 101 bits (242), Expect = 9e-21
Identities = 81/274 (29%), Positives = 132/274 (48%), Gaps = 9/274 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + A + G ++ L++ G +E+D+ GR L+ G +CV++LL++ ++
Sbjct: 163 TPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNI-- 220
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKEL 204
D L AA V++L +HGADVN +D P L+ L + + +
Sbjct: 221 -DQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYF 279
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
LE GA + T LHV+ G ++L+ ADV AA K +AL AA GH
Sbjct: 280 LENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNE-KRSALQSAAWQGH 338
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
+ +LL++HGA +D +G T L +A ++VV++L++ AD D GRT +
Sbjct: 339 VKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRV 398
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
A G I +LL GA ++ + +P+H
Sbjct: 399 AAKNG--HSQIIKLLEKYGA--SSLNGCSPSPVH 428
Score = 75.8 bits (178), Expect = 5e-13
Identities = 63/197 (31%), Positives = 96/197 (48%), Gaps = 5/197 (2%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+ R A+ A G ++ L G D + D GR L++ L + L++G
Sbjct: 224 GYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENG 283
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPE 199
A+ D+ T LH + + V+VLIA+ ADVNA ++ RS L A +
Sbjct: 284 ANVEASDAEGR---TALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVK 340
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
VV+ L+E GA D T L +AA G ++LL GAD A G+ TA+ +A
Sbjct: 341 VVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGR-TAMRVA 399
Query: 260 AEDGHAECARLLLDHGA 276
A++GH++ +LL +GA
Sbjct: 400 AKNGHSQIIKLLEKYGA 416
>BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 616
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 201 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 258
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 259 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 318
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 319 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 378
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 379 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 438
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 439 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 490
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 254 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 313
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 314 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 370
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 371 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 429
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 430 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 489
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 490 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 544
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 545 ASGANVHATTATGDTALTY 563
Score = 102 bits (244), Expect = 5e-21
Identities = 94/296 (31%), Positives = 138/296 (46%), Gaps = 10/296 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 296 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 355
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 356 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 413
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 414 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 472
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 473 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 529
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
A G ++ + LL++GA+ +A G T L A N + +LL G D+
Sbjct: 530 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 583
Score = 90.6 bits (215), Expect = 2e-17
Identities = 85/269 (31%), Positives = 123/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD G N E+ L C+A LA V + + +
Sbjct: 201 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 259
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 260 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 319
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 320 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 378
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 379 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 435
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 436 CGGHVELAALLIERGANLEEVNDEGYTPL 464
Score = 84.6 bits (200), Expect = 1e-15
Identities = 76/242 (31%), Positives = 113/242 (46%), Gaps = 12/242 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 363 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 422
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 423 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 478
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 479 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 534
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ K D +T L
Sbjct: 535 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL-DKQEDMKTIL 593
Query: 323 HG 324
G
Sbjct: 594 EG 595
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 201 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 260
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 261 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 319
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 320 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 377
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 378 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 432
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 189 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 248
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 249 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 308
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 309 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 366
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 367 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 398
>BC004457-1|AAH04457.2| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 269
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 270 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 329
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 450 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 265 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 324
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 325 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 381
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 382 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 440
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 441 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 501 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 556 ASGANVHATTATGDTALTY 574
Score = 102 bits (244), Expect = 5e-21
Identities = 94/296 (31%), Positives = 138/296 (46%), Gaps = 10/296 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 307 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 366
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 367 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 483
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 484 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 540
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
A G ++ + LL++GA+ +A G T L A N + +LL G D+
Sbjct: 541 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 594
Score = 90.6 bits (215), Expect = 2e-17
Identities = 85/269 (31%), Positives = 123/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD G N E+ L C+A LA V + + +
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 270
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 271 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 330
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 331 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 446
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 447 CGGHVELAALLIERGANLEEVNDEGYTPL 475
Score = 84.6 bits (200), Expect = 1e-15
Identities = 76/242 (31%), Positives = 113/242 (46%), Gaps = 12/242 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 434 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 489
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 545
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ K D +T L
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL-DKQEDMKTIL 604
Query: 323 HG 324
G
Sbjct: 605 EG 606
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 330
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 388
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 389 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 443
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 200 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 260 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 377
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 378 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 409
>AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein.
Length = 1486
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 226 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 283
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 284 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 343
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 344 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 403
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 404 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 463
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 464 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 515
Score = 121 bits (291), Expect = 1e-26
Identities = 103/325 (31%), Positives = 143/325 (44%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ L+ + D G T L L+ G V++LLD G
Sbjct: 1090 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 1149
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V +L+A GA+ + +SD +PL A ++K L
Sbjct: 1150 --QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 1207
Query: 205 LEAGACPD--TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA + T +PL +AA G KLLL+ G+D+ A + + TAL LA
Sbjct: 1208 LNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQ 1267
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G AE LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 1268 GRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 1327
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +A+ V LL+ G DV
Sbjct: 1328 ALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAA 1387
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + +YL K
Sbjct: 1388 DNRKITPLMSAFRKGHVKVVQYLVK 1412
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 279 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 338
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 339 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 395
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 396 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 454
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 455 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 514
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 515 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 569
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 570 ASGANVHATTATGDTALTY 588
Score = 102 bits (244), Expect = 5e-21
Identities = 94/296 (31%), Positives = 138/296 (46%), Gaps = 10/296 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 321 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 380
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 381 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 438
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 439 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 497
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 498 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 554
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
A G ++ + LL++GA+ +A G T L A N + +LL G D+
Sbjct: 555 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 608
Score = 94.7 bits (225), Expect = 1e-18
Identities = 99/328 (30%), Positives = 146/328 (44%), Gaps = 33/328 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 388 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 447
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 448 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 503
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 504 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 559
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD------- 315
GH E + LL GA++ G T L A +V ++L+ AD+ ++
Sbjct: 560 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDKQEDMKTILE 619
Query: 316 ------------ADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAAL 362
GRTPL A R C + + L+S GA+ N A N +T + +A
Sbjct: 620 GIDPAKHQEHESEGGRTPLMKA-ARAGHLCTV-QFLISKGANVNRATANNDHTVVSLACA 677
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A V LLL +G D T R G + L
Sbjct: 678 GGHLAVVELLLAHGADPTHRLKDGSTML 705
Score = 90.6 bits (215), Expect = 2e-17
Identities = 85/269 (31%), Positives = 123/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD G N E+ L C+A LA V + + +
Sbjct: 226 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 284
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 285 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 344
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 345 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 403
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 404 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 460
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 461 CGGHVELAALLIERGANLEEVNDEGYTPL 489
Score = 86.2 bits (204), Expect = 4e-16
Identities = 101/329 (30%), Positives = 143/329 (43%), Gaps = 31/329 (9%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
+ TA++ AC G + LL G + D+ + L L+ G E LL++ GA+
Sbjct: 419 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGAN- 477
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVLSDAPEVV 201
+ + TPL AA V +L+A GA++NA + + L A EV
Sbjct: 478 --LEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVA 535
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
L++AGA ++ TPL A+ G K LL +GA+V A G TAL A E
Sbjct: 536 DFLIKAGA---DIELGCSTPLMEASQEGHLELVKYLLASGANVHATTATGD-TALTYACE 591
Query: 262 DGHAECARLLLDHGAHID-------------------WPNFRGQTPLHLATLAQSLEVVE 302
+GH + A +LL GA +D + G+TPL A A L V+
Sbjct: 592 NGHTDVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQ 651
Query: 303 MLVDRCADV-RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAA 361
L+ + A+V RA + T + A G A + LLL+ GADP G T L AA
Sbjct: 652 FLISKGANVNRATANNDHTVVSLACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAA 709
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ V LLDY +V VS L
Sbjct: 710 KGGHTNVVSYLLDYPNNVLSVPTTDVSQL 738
Score = 74.5 bits (175), Expect = 1e-12
Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 10/256 (3%)
Query: 143 PNTWDSSTETKA--TPLHCAASAKSLACVKVLIAH-GADVNAGLSDR--SPLHYAVLSDA 197
P +SS++T TP C+ + ++A + + D++A + L A
Sbjct: 1041 PTGSNSSSQTTECLTPESCSQTTSNVASQSMPPVYPSVDIDAHTESNHDTALTLACAGGH 1100
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH 257
E+V L+ A + TPL +AA+ G ++LL+ G D+ A K T L
Sbjct: 1101 EELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLS 1160
Query: 258 LAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
LA G E LLL GA+ + N TPL LA + ++++L++ A++ ++
Sbjct: 1161 LACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGS 1220
Query: 318 --GRTPLHGAIVRGARACDIARLLLSAGADPNA-ADNFGYTPLHIAALNEFSACVLLLLD 374
G +PL A + G +LLL G+D NA + T L +A + V LLLD
Sbjct: 1221 KLGISPLMLAAMNG--HVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLD 1278
Query: 375 YGGDVTLRTNGGVSAL 390
+V R G++ L
Sbjct: 1279 RKANVEHRAKTGLTPL 1294
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 226 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 285
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 286 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 344
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 345 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 402
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 403 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 457
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 214 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 273
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 274 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 333
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 334 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 391
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 392 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 423
>AK022041-1|BAB13958.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ11979 fis, clone HEMBB1001282, weakly similar to
ANKYRIN R. ).
Length = 435
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 20 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 77
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 78 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 137
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 138 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 197
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 198 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 257
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 258 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 309
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 73 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 132
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 133 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 189
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 190 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 248
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 249 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 308
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 309 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 363
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 364 ASGANVHATTATGDTALTY 382
Score = 102 bits (244), Expect = 5e-21
Identities = 94/296 (31%), Positives = 138/296 (46%), Gaps = 10/296 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 115 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 174
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 175 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 232
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 233 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 291
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 292 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 348
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
A G ++ + LL++GA+ +A G T L A N + +LL G D+
Sbjct: 349 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 402
Score = 90.6 bits (215), Expect = 2e-17
Identities = 85/269 (31%), Positives = 123/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD G N E+ L C+A LA V + + +
Sbjct: 20 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 78
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 79 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 138
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 139 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 197
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 198 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 254
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 255 CGGHVELAALLIERGANLEEVNDEGYTPL 283
Score = 84.6 bits (200), Expect = 1e-15
Identities = 76/242 (31%), Positives = 113/242 (46%), Gaps = 12/242 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 182 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 241
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 242 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 297
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 298 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 353
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ K D +T L
Sbjct: 354 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL-DKQEDMKTIL 412
Query: 323 HG 324
G
Sbjct: 413 EG 414
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 20 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 79
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 80 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 138
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 139 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 196
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 197 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 251
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 8 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 67
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 68 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 127
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 128 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 185
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 186 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 217
>AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 2 protein.
Length = 2617
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 269
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 270 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 329
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 450 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Score = 121 bits (291), Expect = 1e-26
Identities = 103/325 (31%), Positives = 143/325 (44%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ L+ + D G T L L+ G V++LLD G
Sbjct: 1057 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 1116
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V +L+A GA+ + +SD +PL A ++K L
Sbjct: 1117 --QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 1174
Query: 205 LEAGACPD--TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA + T +PL +AA G KLLL+ G+D+ A + + TAL LA
Sbjct: 1175 LNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQ 1234
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G AE LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 1235 GRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 1294
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +A+ V LL+ G DV
Sbjct: 1295 ALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAA 1354
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + +YL K
Sbjct: 1355 DNRKITPLMSAFRKGHVKVVQYLVK 1379
Score = 113 bits (271), Expect = 3e-24
Identities = 99/309 (32%), Positives = 145/309 (46%), Gaps = 14/309 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 434 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 489
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 545
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ + GRTPL
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPL 605
Query: 323 HGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A R C + + L+S GA+ N A N +T + +A A V LLL +G D T
Sbjct: 606 MKA-ARAGHLCTV-QFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTH 663
Query: 382 RTNGGVSAL 390
R G + L
Sbjct: 664 RLKDGSTML 672
Score = 106 bits (254), Expect = 3e-22
Identities = 97/307 (31%), Positives = 143/307 (46%), Gaps = 10/307 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 307 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 366
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 367 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 483
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 484 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 540
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G ++ + LL++GA+ +A G T L A N + +LL G D+ +
Sbjct: 541 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHES 598
Query: 384 NGGVSAL 390
GG + L
Sbjct: 599 EGGRTPL 605
Score = 103 bits (247), Expect = 2e-21
Identities = 100/310 (32%), Positives = 143/310 (46%), Gaps = 12/310 (3%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
+ TA++ AC G + LL G + D+ + L L+ G E LL++ GA+
Sbjct: 405 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGAN- 463
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVLSDAPEVV 201
+ + TPL AA V +L+A GA++NA + + L A EV
Sbjct: 464 --LEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVA 521
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
L++AGA ++ TPL A+ G K LL +GA+V A G TAL A E
Sbjct: 522 DFLIKAGA---DIELGCSTPLMEASQEGHLELVKYLLASGANVHATTATGD-TALTYACE 577
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRT 320
+GH + A +LL GA ++ + G+TPL A A L V+ L+ + A+V RA + T
Sbjct: 578 NGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHT 637
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
+ A G A + LLL+ GADP G T L AA + V LLDY +V
Sbjct: 638 VVSLACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVL 695
Query: 381 LRTNGGVSAL 390
VS L
Sbjct: 696 SVPTTDVSQL 705
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 265 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 324
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 325 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 381
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 382 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 440
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 441 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 501 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 556 ASGANVHATTATGDTALTY 574
Score = 74.5 bits (175), Expect = 1e-12
Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 10/256 (3%)
Query: 143 PNTWDSSTETKA--TPLHCAASAKSLACVKVLIAH-GADVNAGLSDR--SPLHYAVLSDA 197
P +SS++T TP C+ + ++A + + D++A + L A
Sbjct: 1008 PTGSNSSSQTTECLTPESCSQTTSNVASQSMPPVYPSVDIDAHTESNHDTALTLACAGGH 1067
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH 257
E+V L+ A + TPL +AA+ G ++LL+ G D+ A K T L
Sbjct: 1068 EELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLS 1127
Query: 258 LAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
LA G E LLL GA+ + N TPL LA + ++++L++ A++ ++
Sbjct: 1128 LACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGS 1187
Query: 318 --GRTPLHGAIVRGARACDIARLLLSAGADPNA-ADNFGYTPLHIAALNEFSACVLLLLD 374
G +PL A + G +LLL G+D NA + T L +A + V LLLD
Sbjct: 1188 KLGISPLMLAAMNG--HVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLD 1245
Query: 375 YGGDVTLRTNGGVSAL 390
+V R G++ L
Sbjct: 1246 RKANVEHRAKTGLTPL 1261
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 330
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 388
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 389 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 443
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 200 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 260 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 377
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 378 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 409
>AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeats
single KH domain protein isoform 1 protein.
Length = 2542
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 269
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 270 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 329
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 450 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Score = 121 bits (291), Expect = 1e-26
Identities = 103/325 (31%), Positives = 143/325 (44%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ L+ + D G T L L+ G V++LLD G
Sbjct: 1057 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 1116
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V +L+A GA+ + +SD +PL A ++K L
Sbjct: 1117 --QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 1174
Query: 205 LEAGACPD--TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA + T +PL +AA G KLLL+ G+D+ A + + TAL LA
Sbjct: 1175 LNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQ 1234
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G AE LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 1235 GRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 1294
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +A+ V LL+ G DV
Sbjct: 1295 ALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAA 1354
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + +YL K
Sbjct: 1355 DNRKITPLMSAFRKGHVKVVQYLVK 1379
Score = 113 bits (271), Expect = 3e-24
Identities = 99/309 (32%), Positives = 145/309 (46%), Gaps = 14/309 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 434 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 489
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 545
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ + GRTPL
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPL 605
Query: 323 HGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A R C + + L+S GA+ N A N +T + +A A V LLL +G D T
Sbjct: 606 MKA-ARAGHLCTV-QFLISKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTH 663
Query: 382 RTNGGVSAL 390
R G + L
Sbjct: 664 RLKDGSTML 672
Score = 106 bits (254), Expect = 3e-22
Identities = 97/307 (31%), Positives = 143/307 (46%), Gaps = 10/307 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 307 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 366
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 367 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 483
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 484 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 540
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A G ++ + LL++GA+ +A G T L A N + +LL G D+ +
Sbjct: 541 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLEHES 598
Query: 384 NGGVSAL 390
GG + L
Sbjct: 599 EGGRTPL 605
Score = 103 bits (247), Expect = 2e-21
Identities = 100/310 (32%), Positives = 143/310 (46%), Gaps = 12/310 (3%)
Query: 84 LRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHP 143
+ TA++ AC G + LL G + D+ + L L+ G E LL++ GA+
Sbjct: 405 MHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGAN- 463
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVLSDAPEVV 201
+ + TPL AA V +L+A GA++NA + + L A EV
Sbjct: 464 --LEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVA 521
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
L++AGA ++ TPL A+ G K LL +GA+V A G TAL A E
Sbjct: 522 DFLIKAGA---DIELGCSTPLMEASQEGHLELVKYLLASGANVHATTATGD-TALTYACE 577
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRT 320
+GH + A +LL GA ++ + G+TPL A A L V+ L+ + A+V RA + T
Sbjct: 578 NGHTDVADVLLQAGADLEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHT 637
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
+ A G A + LLL+ GADP G T L AA + V LLDY +V
Sbjct: 638 VVSLACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVL 695
Query: 381 LRTNGGVSAL 390
VS L
Sbjct: 696 SVPTTDVSQL 705
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 265 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 324
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 325 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 381
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 382 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 440
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 441 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 501 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 556 ASGANVHATTATGDTALTY 574
Score = 74.5 bits (175), Expect = 1e-12
Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 10/256 (3%)
Query: 143 PNTWDSSTETKA--TPLHCAASAKSLACVKVLIAH-GADVNAGLSDR--SPLHYAVLSDA 197
P +SS++T TP C+ + ++A + + D++A + L A
Sbjct: 1008 PTGSNSSSQTTECLTPESCSQTTSNVASQSMPPVYPSVDIDAHTESNHDTALTLACAGGH 1067
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH 257
E+V L+ A + TPL +AA+ G ++LL+ G D+ A K T L
Sbjct: 1068 EELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLS 1127
Query: 258 LAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
LA G E LLL GA+ + N TPL LA + ++++L++ A++ ++
Sbjct: 1128 LACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGS 1187
Query: 318 --GRTPLHGAIVRGARACDIARLLLSAGADPNA-ADNFGYTPLHIAALNEFSACVLLLLD 374
G +PL A + G +LLL G+D NA + T L +A + V LLLD
Sbjct: 1188 KLGISPLMLAAMNG--HVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLD 1245
Query: 375 YGGDVTLRTNGGVSAL 390
+V R G++ L
Sbjct: 1246 RKANVEHRAKTGLTPL 1261
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 330
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 388
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 389 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 443
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 200 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 260 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 377
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 378 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 409
>AF258557-1|AAG23760.1| 627|Homo sapiens PP2500 protein.
Length = 627
Score = 123 bits (297), Expect = 2e-27
Identities = 96/294 (32%), Positives = 135/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL G +E + G + L L+C G E ++LL H N D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 269
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 270 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 329
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 450 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 265 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 324
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 325 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 381
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 382 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 440
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 441 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 501 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 556 ASGANVHATTATGDTALTY 574
Score = 102 bits (244), Expect = 5e-21
Identities = 94/296 (31%), Positives = 138/296 (46%), Gaps = 10/296 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 307 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 366
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 367 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 483
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 484 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 540
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
A G ++ + LL++GA+ +A G T L A N + +LL G D+
Sbjct: 541 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 594
Score = 90.6 bits (215), Expect = 2e-17
Identities = 85/269 (31%), Positives = 123/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD G N E+ L C+A LA V + + +
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 270
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 271 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 330
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 331 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 446
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 447 CGGHVELAALLIERGANLEEVNDEGYTPL 475
Score = 84.6 bits (200), Expect = 1e-15
Identities = 76/242 (31%), Positives = 113/242 (46%), Gaps = 12/242 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 434 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 489
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 545
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ K D +T L
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL-DKQEDMKTIL 604
Query: 323 HG 324
G
Sbjct: 605 EG 606
Score = 74.1 bits (174), Expect = 2e-12
Identities = 73/235 (31%), Positives = 104/235 (44%), Gaps = 6/235 (2%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVF 217
A S + V+ L+ G VN + S L A + E+ + LL A D
Sbjct: 212 ACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLAMHANVEDRGNKG 271
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL A+S G KLLL ADV + G TAL A G + ++LL+ GA+
Sbjct: 272 DITPLMAASSGGYLDIVKLLLLHDADVNSQSATGN-TALTYACAGGFVDIVKVLLNEGAN 330
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR-TPLHGAIVRGARACDIA 336
I+ N G TPL A A +EV +L+D A + + + + L A +G D+
Sbjct: 331 IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGH--LDMV 388
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R LL AGAD + +T L A ++ LLLD G V + + S L+
Sbjct: 389 RFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLT 443
Score = 71.7 bits (168), Expect = 9e-12
Identities = 61/212 (28%), Positives = 97/212 (45%), Gaps = 3/212 (1%)
Query: 180 NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
NAG D L A V++LL+ G + E+ L +A S G ++LL
Sbjct: 200 NAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNEHTEEGESLLCLACSAGYYELAQVLLA 259
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+V G T L A+ G+ + +LLL H A ++ + G T L A ++
Sbjct: 260 MHANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVD 319
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN-FGYTPLH 358
+V++L++ A++ + +G TPL A G ++AR+LL GA N N F + L
Sbjct: 320 IVKVLLNEGANIEDHNENGHTPLMEAASAG--HVEVARVLLDHGAGINTHSNEFKESALT 377
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A V LL+ G D +T+ +AL
Sbjct: 378 LACYKGHLDMVRFLLEAGADQEHKTDEMHTAL 409
>AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein
protein.
Length = 968
Score = 121 bits (291), Expect = 1e-26
Identities = 103/325 (31%), Positives = 143/325 (44%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ L+ + D G T L L+ G V++LLD G
Sbjct: 551 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 610
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V +L+A GA+ + +SD +PL A ++K L
Sbjct: 611 --QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 668
Query: 205 LEAGACPD--TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA + T +PL +AA G KLLL+ G+D+ A + + TAL LA
Sbjct: 669 LNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQ 728
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G AE LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 729 GRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 788
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +A+ V LL+ G DV
Sbjct: 789 ALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAA 848
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + +YL K
Sbjct: 849 DNRKITPLMSAFRKGHVKVVQYLVK 873
Score = 74.5 bits (175), Expect = 1e-12
Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 10/256 (3%)
Query: 143 PNTWDSSTETKA--TPLHCAASAKSLACVKVLIAH-GADVNAGLSDR--SPLHYAVLSDA 197
P +SS++T TP C+ + ++A + + D++A + L A
Sbjct: 502 PTGSNSSSQTTECLTPESCSQTTSNVASQSMPPVYPSVDIDAHTESNHDTALTLACAGGH 561
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH 257
E+V L+ A + TPL +AA+ G ++LL+ G D+ A K T L
Sbjct: 562 EELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLS 621
Query: 258 LAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
LA G E LLL GA+ + N TPL LA + ++++L++ A++ ++
Sbjct: 622 LACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGS 681
Query: 318 --GRTPLHGAIVRGARACDIARLLLSAGADPNA-ADNFGYTPLHIAALNEFSACVLLLLD 374
G +PL A + G +LLL G+D NA + T L +A + V LLLD
Sbjct: 682 KLGISPLMLAAMNG--HVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLD 739
Query: 375 YGGDVTLRTNGGVSAL 390
+V R G++ L
Sbjct: 740 RKANVEHRAKTGLTPL 755
Score = 58.0 bits (134), Expect = 1e-07
Identities = 64/191 (33%), Positives = 83/191 (43%), Gaps = 23/191 (12%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
TPL A+ G K LL +GA+V A G TAL A E+GH + A +LL GA +D
Sbjct: 12 TPLMEASQEGHLELVKYLLASGANVHATTATGD-TALTYACENGHTDVADVLLQAGADLD 70
Query: 280 -------------------WPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGR 319
+ G+TPL A A L V+ L+ + A+V RA +
Sbjct: 71 KQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDH 130
Query: 320 TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
T + A G A + LLL+ GADP G T L AA + V LLDY +V
Sbjct: 131 TVVSLACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNV 188
Query: 380 TLRTNGGVSAL 390
VS L
Sbjct: 189 LSVPTTDVSQL 199
Score = 48.0 bits (109), Expect = 1e-04
Identities = 51/171 (29%), Positives = 75/171 (43%), Gaps = 26/171 (15%)
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGAD+ G +T L A+++GH E + LL GA++ G T L A +
Sbjct: 2 AGADIEL----GCSTPLMEASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTD 57
Query: 300 VVEMLVDRCADVRAKD-------------------ADGRTPLHGAIVRGARACDIARLLL 340
V ++L+ AD+ ++ GRTPL A R C + + L+
Sbjct: 58 VADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKA-ARAGHLCTV-QFLI 115
Query: 341 SAGADPN-AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
S GA+ N A N +T + +A A V LLL +G D T R G + L
Sbjct: 116 SKGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTML 166
Score = 34.7 bits (76), Expect = 1.2
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 2/127 (1%)
Query: 115 DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIA 174
D L + +E +K +L+ + +E TPL AA A L V+ LI+
Sbjct: 57 DVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLIS 116
Query: 175 HGADVNAGL--SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
GA+VN +D + + A VV+ LL GA P T L AA G +
Sbjct: 117 KGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTN 176
Query: 233 CTKLLLN 239
LL+
Sbjct: 177 VVSYLLD 183
>AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens
cDNA FLJ20288 fis, clone HEP04414. ).
Length = 686
Score = 121 bits (291), Expect = 1e-26
Identities = 103/325 (31%), Positives = 143/325 (44%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ L+ + D G T L L+ G V++LLD G
Sbjct: 268 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 327
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V +L+A GA+ + +SD +PL A ++K L
Sbjct: 328 --QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 385
Query: 205 LEAGACPD--TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA + T +PL +AA G KLLL+ G+D+ A + + TAL LA
Sbjct: 386 LNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQ 445
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G AE LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 446 GRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 505
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +A+ V LL+ G DV
Sbjct: 506 ALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAA 565
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + +YL K
Sbjct: 566 DNRKITPLMSAFRKGHVKVVQYLVK 590
Score = 77.4 bits (182), Expect = 2e-13
Identities = 78/287 (27%), Positives = 127/287 (44%), Gaps = 12/287 (4%)
Query: 111 DELDDAGRTCLHLS-CLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACV 169
D+ + RT S L+G ++ V + G++ + S T TP C+ + ++A
Sbjct: 191 DQSQEPDRTSQENSPALLGVQKAVSTRVPTGSNSS---SQTTECLTPESCSQTTSNVASQ 247
Query: 170 KVLIAH-GADVNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAA 226
+ + DV+A + L A E+V L+ A + TPL +AA
Sbjct: 248 SMPPVYPSVDVDAHTESNHDTALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAA 307
Query: 227 SLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ 286
+ G ++LL+ G D+ A K T L LA G E LLL GA+ + N
Sbjct: 308 TAGHVGVVEILLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDY 367
Query: 287 TPLHLATLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLSAGA 344
TPL LA + ++++L++ A++ ++ G +PL A + G +LLL G+
Sbjct: 368 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNG--HVPAVKLLLDMGS 425
Query: 345 DPNA-ADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
D NA + T L +A + V LLLD +V R G++ L
Sbjct: 426 DINAQIETNRNTALTLACFQGRAEVVSLLLDRKANVEHRAKTGLTPL 472
Score = 53.2 bits (122), Expect = 3e-06
Identities = 61/186 (32%), Positives = 80/186 (43%), Gaps = 23/186 (12%)
Query: 225 AASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID----- 279
A+ G K LL +GA+V A G TAL A E+GH + A +LL GA +D
Sbjct: 3 ASQEGHLELVKYLLASGANVHATTATGD-TALTYACENGHTDVADVLLQAGADLDKQEDM 61
Query: 280 --------------WPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTPLHG 324
+ G+TPL A A L V+ L+ + A+V RA + T +
Sbjct: 62 KTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSL 121
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
A G A + LLL+ GADP G T L AA + V LLDY +V
Sbjct: 122 ACAGGHLA--VVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLDYPNNVLSVPT 179
Query: 385 GGVSAL 390
VS L
Sbjct: 180 TDVSQL 185
Score = 45.2 bits (102), Expect = 9e-04
Identities = 52/167 (31%), Positives = 67/167 (40%), Gaps = 20/167 (11%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT----- 213
A+ L VK L+A GA+V+A + + L YA + +V LL+AGA D
Sbjct: 3 ASQEGHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADLDKQEDMK 62
Query: 214 -------PQVFTE-------TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
P E TPL AA G + L++ GA+V A T + LA
Sbjct: 63 TILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLISKGANVNRATANNDHTVVSLA 122
Query: 260 AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
GH LLL HGA G T L A VV L+D
Sbjct: 123 CAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTNVVSYLLD 169
Score = 37.1 bits (82), Expect = 0.23
Identities = 65/284 (22%), Positives = 110/284 (38%), Gaps = 20/284 (7%)
Query: 115 DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIA 174
D L + +E +K +L+ + +E TPL AA A L V+ LI+
Sbjct: 43 DVADVLLQAGADLDKQEDMKTILEGIDPAKHQEHESEGGRTPLMKAARAGHLCTVQFLIS 102
Query: 175 HGADVNAGL--SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
GA+VN +D + + A VV+ LL GA P T L AA G +
Sbjct: 103 KGANVNRATANNDHTVVSLACAGGHLAVVELLLAHGADPTHRLKDGSTMLIEAAKGGHTN 162
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
LL+ +V ++ + L ++D E R ++ + T +
Sbjct: 163 VVSYLLDYPNNV-LSVPTTDVSQLPPPSQDQSQEPDRTSQENSPALLGVQKAVSTRVPTG 221
Query: 293 TLAQSLEVVEMLVDRCADVRAKDA-DGRTPLHGAIVRGAR-----------AC-----DI 335
+ + S + + C+ + A P++ ++ A AC ++
Sbjct: 222 SNSSSQTTECLTPESCSQTTSNVASQSMPPVYPSVDVDAHTESNHDTALTLACAGGHEEL 281
Query: 336 ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+L++ A D G+TPL +AA V +LLD GGD+
Sbjct: 282 VSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDI 325
>AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein
protein.
Length = 532
Score = 121 bits (291), Expect = 1e-26
Identities = 103/325 (31%), Positives = 143/325 (44%), Gaps = 5/325 (1%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ AC G L+ L+ + D G T L L+ G V++LLD G
Sbjct: 134 TALTLACAGGHEELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEA 193
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKEL 204
S TK TPL A S V +L+A GA+ + +SD +PL A ++K L
Sbjct: 194 --QSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKIL 251
Query: 205 LEAGACPD--TPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
L AGA + T +PL +AA G KLLL+ G+D+ A + + TAL LA
Sbjct: 252 LNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDINAQIETNRNTALTLACFQ 311
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
G AE LLLD A+++ G TPL A EV +L+D+ ADV A
Sbjct: 312 GRAEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVLLDKGADVNAPPVPSSRDT 371
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
I LL+ GA + + G TPL +A+ V LL+ G DV
Sbjct: 372 ALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNGGHFDVVQLLVQAGADVDAA 431
Query: 383 TNGGVSALSFIVRRVPDVIPRYLCK 407
N ++ L R+ + +YL K
Sbjct: 432 DNRKITPLMSAFRKGHVKVVQYLVK 456
Score = 74.5 bits (175), Expect = 1e-12
Identities = 71/256 (27%), Positives = 115/256 (44%), Gaps = 10/256 (3%)
Query: 143 PNTWDSSTETKA--TPLHCAASAKSLACVKVLIAH-GADVNAGLSDR--SPLHYAVLSDA 197
P +SS++T TP C+ + ++A + + D++A + L A
Sbjct: 85 PTGSNSSSQTTECLTPESCSQTTSNVASQSMPPVYPSVDIDAHTESNHDTALTLACAGGH 144
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH 257
E+V L+ A + TPL +AA+ G ++LL+ G D+ A K T L
Sbjct: 145 EELVSVLIARDAKIEHRDKKGFTPLILAATAGHVGVVEILLDKGGDIEAQSERTKDTPLS 204
Query: 258 LAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
LA G E LLL GA+ + N TPL LA + ++++L++ A++ ++
Sbjct: 205 LACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGGYVNIIKILLNAGAEINSRTGS 264
Query: 318 --GRTPLHGAIVRGARACDIARLLLSAGADPNA-ADNFGYTPLHIAALNEFSACVLLLLD 374
G +PL A + G +LLL G+D NA + T L +A + V LLLD
Sbjct: 265 KLGISPLMLAAMNG--HVPAVKLLLDMGSDINAQIETNRNTALTLACFQGRAEVVSLLLD 322
Query: 375 YGGDVTLRTNGGVSAL 390
+V R G++ L
Sbjct: 323 RKANVEHRAKTGLTPL 338
>AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 120 bits (290), Expect = 1e-26
Identities = 83/246 (33%), Positives = 121/246 (49%), Gaps = 8/246 (3%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDR 186
G E V L++ GA + T+ TPLH AA+ L V++L+ G D++ D+
Sbjct: 21 GQTENVVQLINKGARV----AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQ 76
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+ LH A + E++ L+ G D T LH A+ G + KLL+ AGA+V A
Sbjct: 77 TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLA 136
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
G TALHLA ++ H++ R+LL G+ D N G T LH+A L ++ +L+
Sbjct: 137 KNKAGN-TALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 195
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
V K+ G T LH A + +A++LL AGAD +N G TPL A +
Sbjct: 196 AFCSVHEKNQAGDTALHVAAALNHK--KVAKILLEAGADTTIVNNAGQTPLETARYHNNP 253
Query: 367 ACVLLL 372
LLL
Sbjct: 254 EVALLL 259
Score = 94.7 bits (225), Expect = 1e-18
Identities = 83/250 (33%), Positives = 113/250 (45%), Gaps = 10/250 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LLK G D D DD +T LH + +VG+ E + L+ G D + T LH A+
Sbjct: 61 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGC---ALDRQDKDGNTALHEASW 117
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+LI GA+V A + + LH A + + + LL AG+ D +T
Sbjct: 118 HGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTC 177
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVAA S +LLL A V G TALH+AA H + A++LL+ GA
Sbjct: 178 LHVAARYNHLSIIRLLLTAFCSVHEKNQAGD-TALHVAAALNHKKVAKILLEAGADTTIV 236
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
N GQTPL A + EV +L + + G TP V AR + LS
Sbjct: 237 NNAGQTPLETARYHNNPEVALLLTKA---PQGSVSAGDTPSSEQAV--ARKEEAREEFLS 291
Query: 342 AGADPNAADN 351
A +P A D+
Sbjct: 292 ASPEPRAKDD 301
Score = 88.6 bits (210), Expect = 7e-17
Identities = 68/200 (34%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L VAA G L+N GA R A+ T LHLAA GH ++LL G +D
Sbjct: 14 LLVAAYKGQTENVVQLINKGA--RVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQ 71
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ QT LH AT+ + E++ L+ + +D DG T LH A G A+LL+
Sbjct: 72 DDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHG--FSQSAKLLIK 129
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
AGA+ A + G T LH+A N S +LL G L+ N G + L R I
Sbjct: 130 AGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSI 189
Query: 402 PRYLCKFDDAVHVSEHELGD 421
R L +VH +++ GD
Sbjct: 190 IRLLLTAFCSVH-EKNQAGD 208
Score = 86.6 bits (205), Expect = 3e-16
Identities = 69/219 (31%), Positives = 99/219 (45%), Gaps = 3/219 (1%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
LI GA V R+PLH A VV+ LL+AG D +T LH A +G+
Sbjct: 29 LINKGARVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNT 88
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ G + G TALH A+ G ++ A+LL+ GA++ N G T LHL
Sbjct: 89 EIIAALIHEGCALDRQDKDGN-TALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHL 147
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
A + +L+ + K+ G T LH + I RLLL+A + +
Sbjct: 148 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLH--VAARYNHLSIIRLLLTAFCSVHEKNQ 205
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G T LH+AA +LL+ G D T+ N G + L
Sbjct: 206 AGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPL 244
Score = 79.8 bits (188), Expect = 3e-14
Identities = 79/282 (28%), Positives = 121/282 (42%), Gaps = 11/282 (3%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S+ + L +L A + G++ + +L+ G + GRT LHL+ G V++
Sbjct: 2 SQQDAVAALSERLLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQI 60
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVL 194
LL G + D + T LH A + + LI G ++ D + LH A
Sbjct: 61 LLKAGCDLDVQDDGDQ---TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASW 117
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+ K L++AGA T LH+A + T++LL AG+ G T
Sbjct: 118 HGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGD-T 176
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH+AA H RLLL + N G T LH+A +V ++L++ AD
Sbjct: 177 CLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIV 236
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
+ G+TPL A R ++A LL A P + + G TP
Sbjct: 237 NNAGQTPLETA--RYHNNPEVALLLTKA---PQGSVSAGDTP 273
Score = 67.3 bits (157), Expect = 2e-10
Identities = 67/233 (28%), Positives = 96/233 (41%), Gaps = 6/233 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G +TA+ A +G + ++ L+ G D D G T LH + G + KLL+ GA+
Sbjct: 74 GDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGAN 133
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVK 202
+ + T A L C S V +L AD+ D + LH A + +++
Sbjct: 134 VLAKNKAGNT-ALHLACQNSHSQSTRVLLLAGSRADLKNNAGD-TCLHVAARYNHLSIIR 191
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL A +T LHVAA+L K+LL AGAD G+ T L A
Sbjct: 192 LLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQ-TPLETARYH 250
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
+ E A LL G TP +A+ E E + + RAKD
Sbjct: 251 NNPEVALLLTKAP---QGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD 300
>AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein
protein.
Length = 1031
Score = 120 bits (290), Expect = 1e-26
Identities = 98/313 (31%), Positives = 146/313 (46%), Gaps = 10/313 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA++ A G ++ +LLK GV+ + D G T L +C G + V+LLL HGA+P+
Sbjct: 73 TALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSV 132
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVK 202
+ + P+ AA V +L+ +GA VN SD+ +PL +A E VK
Sbjct: 133 --TGLQYSVYPIIWAAGRGHADIVHLLLQNGAKVNC--SDKYGTTPLVWAARKGHLECVK 188
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA D + T L VA G K +L +V G TAL +A+++
Sbjct: 189 HLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGN-TALMIASKE 247
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LLD G +++ P+ G T L A +E+V L+ + AD+ + D +T L
Sbjct: 248 GHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTAL 307
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
+ A+ +G + R +L D G TPL A V LLLD G V+
Sbjct: 308 YWAVEKG--NATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAV 365
Query: 383 TNGGVSALSFIVR 395
G + L +R
Sbjct: 366 DKKGDTPLHIAIR 378
Score = 101 bits (241), Expect = 1e-20
Identities = 93/290 (32%), Positives = 127/290 (43%), Gaps = 8/290 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELD-DAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
TA++WAC+ G++ ++ LL G +P + + G + V LLL +GA N
Sbjct: 106 TALMWACYKGRTDVVELLLSHGANPSVTGLQYSVYPIIWAAGRGHADIVHLLLQNGAKVN 165
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D + TPL AA L CVK L+A GADV+ G + + L AV + VKE
Sbjct: 166 CSD---KYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKE 222
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
+L+ + T L +A+ G + LL+AG V G T L A G
Sbjct: 223 ILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGD-TVLIGAVRGG 281
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H E R LL A ID +T L+ A + +V ++ D DG TPL
Sbjct: 282 HVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLI 341
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
A R ++ LLL GA +A D G TPLHIA LLL
Sbjct: 342 KATKM--RNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLL 389
Score = 90.6 bits (215), Expect = 2e-17
Identities = 90/296 (30%), Positives = 131/296 (44%), Gaps = 8/296 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ D DE ++ G+T L ++ G+ E VK L+ +GA+ N D T L A+
Sbjct: 24 LLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLD---NWTALISASK 80
Query: 163 AKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTET 220
+ V+ L+ G ++ + + + L +A +VV+ LL GA P T ++
Sbjct: 81 EGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLQYSVY 140
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
P+ AA G A LLL GA V + G T L AA GH EC + LL GA +D
Sbjct: 141 PIIWAAGRGHADIVHLLLQNGAKVNCSDKYG-TTPLVWAARKGHLECVKHLLAMGADVDQ 199
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
T L +A + V+ ++ R +V D DG T L A G +I + LL
Sbjct: 200 EGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEG--HTEIVQDLL 257
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
AG N D G T L A V LL D+ +R +AL + V +
Sbjct: 258 DAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEK 313
Score = 72.9 bits (171), Expect = 4e-12
Identities = 66/214 (30%), Positives = 93/214 (43%), Gaps = 5/214 (2%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
L +S ++Y + P +K LLE D +TPL +AA G+ K L+ GA
Sbjct: 4 LISQSVINYVEEENIP-ALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGA 62
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+ TAL A+++GH LL G +++ + G T L A +VVE
Sbjct: 63 NCNLE-DLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVE 121
Query: 303 MLVDRCADVRAKDADGRT-PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAA 361
+L+ A+ P+ A RG DI LLL GA N +D +G TPL AA
Sbjct: 122 LLLSHGANPSVTGLQYSVYPIIWAAGRG--HADIVHLLLQNGAKVNCSDKYGTTPLVWAA 179
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
CV LL G DV ++AL V+
Sbjct: 180 RKGHLECVKHLLAMGADVDQEGANSMTALIVAVK 213
Score = 69.7 bits (163), Expect = 3e-11
Identities = 67/230 (29%), Positives = 101/230 (43%), Gaps = 9/230 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++WA G + LL MG D D+ T L ++ G + VK +L + N
Sbjct: 173 TPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNL 232
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP---LHYAVLSDAPEVVK 202
D T L A+ V+ L+ G VN + DRS L AV E+V+
Sbjct: 233 TDKDGNTA---LMIASKEGHTEIVQDLLDAGTYVN--IPDRSGDTVLIGAVRGGHVEIVR 287
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL+ A D +T L+ A G+A+ + +L D G+ T L A +
Sbjct: 288 ALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGE-TPLIKATKM 346
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
+ E LLLD GA + + +G TPLH+A +S ++ E+L+ D R
Sbjct: 347 RNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGR 396
Score = 66.5 bits (155), Expect = 3e-10
Identities = 65/218 (29%), Positives = 106/218 (48%), Gaps = 14/218 (6%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G TA++ A G + + ++LK + + D G T L ++ G E V+ LLD G
Sbjct: 201 GANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 260
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPE 199
+ N D S + T L A + V+ L+ AD++ G +++ L++AV
Sbjct: 261 TYVNIPDRSGD---TVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNAT 317
Query: 200 VVKELLEAGACPDTPQVFT---ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
+V+++L+ PDT ++ T ETPL A + + +LLL+ GA V A G T L
Sbjct: 318 MVRDILQCN--PDT-EICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGD-TPL 373
Query: 257 HLAAEDGHAECARLLLDH---GAHIDWPNFRGQTPLHL 291
H+A + A LLL + G + PN G+TP ++
Sbjct: 374 HIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNI 411
Score = 53.6 bits (123), Expect = 2e-06
Identities = 48/163 (29%), Positives = 74/163 (45%), Gaps = 4/163 (2%)
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL 294
K LL DV G+ T L +AAE G+ E + L+ +GA+ + + T L A+
Sbjct: 22 KALLEKCKDVDERNECGQ-TPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASK 80
Query: 295 AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD-NFG 353
+ +VE L+ ++ +D G T L A +G D+ LLLS GA+P+ +
Sbjct: 81 EGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKG--RTDVVELLLSHGANPSVTGLQYS 138
Query: 354 YTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
P+ AA + V LLL G V G + L + R+
Sbjct: 139 VYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARK 181
Score = 46.4 bits (105), Expect = 4e-04
Identities = 51/183 (27%), Positives = 73/183 (39%), Gaps = 11/183 (6%)
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
E+ + + LL+ +D N GQTPL +A +LE+V+ L+ A+ +D D T
Sbjct: 14 EEENIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWT 73
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
L A G I LL G + D G+T L A + V LLL +G
Sbjct: 74 ALISASKEG--HVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHG---- 127
Query: 381 LRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHELGDVDCELTIDFRPLVPCLTRG 440
N V+ L + V + R D VH+ V+C PLV +G
Sbjct: 128 --ANPSVTGLQYSVYPIIWAAGR---GHADIVHLLLQNGAKVNCSDKYGTTPLVWAARKG 182
Query: 441 EAE 443
E
Sbjct: 183 HLE 185
>AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 120 bits (290), Expect = 1e-26
Identities = 83/246 (33%), Positives = 121/246 (49%), Gaps = 8/246 (3%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDR 186
G E V L++ GA + T+ TPLH AA+ L V++L+ G D++ D+
Sbjct: 21 GQTENVVQLINKGARV----AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQ 76
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+ LH A + E++ L+ G D T LH A+ G + KLL+ AGA+V A
Sbjct: 77 TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLA 136
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
G TALHLA ++ H++ R+LL G+ D N G T LH+A L ++ +L+
Sbjct: 137 KNKAGN-TALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 195
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
V K+ G T LH A + +A++LL AGAD +N G TPL A +
Sbjct: 196 AFCSVHEKNQAGDTALHVAAALNHK--KVAKILLEAGADTTIVNNAGQTPLETARYHNNP 253
Query: 367 ACVLLL 372
LLL
Sbjct: 254 EVALLL 259
Score = 94.7 bits (225), Expect = 1e-18
Identities = 83/250 (33%), Positives = 113/250 (45%), Gaps = 10/250 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LLK G D D DD +T LH + +VG+ E + L+ G D + T LH A+
Sbjct: 61 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGC---ALDRQDKDGNTALHEASW 117
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+LI GA+V A + + LH A + + + LL AG+ D +T
Sbjct: 118 HGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTC 177
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVAA S +LLL A V G TALH+AA H + A++LL+ GA
Sbjct: 178 LHVAARYNHLSIIRLLLTAFCSVHEKNQAGD-TALHVAAALNHKKVAKILLEAGADTTIV 236
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
N GQTPL A + EV +L + + G TP V AR + LS
Sbjct: 237 NNAGQTPLETARYHNNPEVALLLTKA---PQGSVSAGDTPSSEQAV--ARKEEAREEFLS 291
Query: 342 AGADPNAADN 351
A +P A D+
Sbjct: 292 ASPEPRAKDD 301
Score = 88.6 bits (210), Expect = 7e-17
Identities = 68/200 (34%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L VAA G L+N GA R A+ T LHLAA GH ++LL G +D
Sbjct: 14 LLVAAYKGQTENVVQLINKGA--RVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQ 71
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ QT LH AT+ + E++ L+ + +D DG T LH A G A+LL+
Sbjct: 72 DDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHG--FSQSAKLLIK 129
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
AGA+ A + G T LH+A N S +LL G L+ N G + L R I
Sbjct: 130 AGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSI 189
Query: 402 PRYLCKFDDAVHVSEHELGD 421
R L +VH +++ GD
Sbjct: 190 IRLLLTAFCSVH-EKNQAGD 208
Score = 86.6 bits (205), Expect = 3e-16
Identities = 69/219 (31%), Positives = 99/219 (45%), Gaps = 3/219 (1%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
LI GA V R+PLH A VV+ LL+AG D +T LH A +G+
Sbjct: 29 LINKGARVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNT 88
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ G + G TALH A+ G ++ A+LL+ GA++ N G T LHL
Sbjct: 89 EIIAALIHEGCALDRQDKDGN-TALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHL 147
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
A + +L+ + K+ G T LH + I RLLL+A + +
Sbjct: 148 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLH--VAARYNHLSIIRLLLTAFCSVHEKNQ 205
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G T LH+AA +LL+ G D T+ N G + L
Sbjct: 206 AGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPL 244
Score = 79.8 bits (188), Expect = 3e-14
Identities = 79/282 (28%), Positives = 121/282 (42%), Gaps = 11/282 (3%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S+ + L +L A + G++ + +L+ G + GRT LHL+ G V++
Sbjct: 2 SQQDAVAALSERLLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQI 60
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVL 194
LL G + D + T LH A + + LI G ++ D + LH A
Sbjct: 61 LLKAGCDLDVQDDGDQ---TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASW 117
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+ K L++AGA T LH+A + T++LL AG+ G T
Sbjct: 118 HGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGD-T 176
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH+AA H RLLL + N G T LH+A +V ++L++ AD
Sbjct: 177 CLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIV 236
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
+ G+TPL A R ++A LL A P + + G TP
Sbjct: 237 NNAGQTPLETA--RYHNNPEVALLLTKA---PQGSVSAGDTP 273
Score = 67.3 bits (157), Expect = 2e-10
Identities = 67/233 (28%), Positives = 96/233 (41%), Gaps = 6/233 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G +TA+ A +G + ++ L+ G D D G T LH + G + KLL+ GA+
Sbjct: 74 GDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGAN 133
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVK 202
+ + T A L C S V +L AD+ D + LH A + +++
Sbjct: 134 VLAKNKAGNT-ALHLACQNSHSQSTRVLLLAGSRADLKNNAGD-TCLHVAARYNHLSIIR 191
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL A +T LHVAA+L K+LL AGAD G+ T L A
Sbjct: 192 LLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQ-TPLETARYH 250
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
+ E A LL G TP +A+ E E + + RAKD
Sbjct: 251 NNPEVALLLTKAP---QGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD 300
>BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6
protein.
Length = 722
Score = 120 bits (289), Expect = 2e-26
Identities = 83/246 (33%), Positives = 121/246 (49%), Gaps = 8/246 (3%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDR 186
G E V L++ GA + T+ TPLH AA+ L V++L+ G D++ D+
Sbjct: 21 GQTENVVQLINKGARV----AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQ 76
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+ LH A + E++ L+ G D T LH A+ G + KLL+ AGA+V A
Sbjct: 77 TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLA 136
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
G TALHLA ++ H++ R+LL G+ D N G T LH+A L ++ +L+
Sbjct: 137 KNKAGN-TALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 195
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
V K+ G T LH A + +A++LL AGAD +N G TPL A +
Sbjct: 196 AFCSVHEKNQAGDTALHVAAALNHK--KVAKILLEAGADTTIVNNAGQTPLETARYHNNP 253
Query: 367 ACVLLL 372
LLL
Sbjct: 254 EVALLL 259
Score = 90.6 bits (215), Expect = 2e-17
Identities = 70/203 (34%), Positives = 96/203 (47%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LLK G D D DD +T LH + +VG+ E + L+ G D + T LH A+
Sbjct: 61 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGC---ALDRQDKDGNTALHEASW 117
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ GA+V A + + LH A + + + LL AG+ D +T
Sbjct: 118 HGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTC 177
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVAA S +LLL A V G TALH+AA H + A++LL+ GA
Sbjct: 178 LHVAARYNHLSIIRLLLTAFCSVHEKNQAGD-TALHVAAALNHKKVAKILLEAGADTTIV 236
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
N GQTPL A + EV +L
Sbjct: 237 NNAGQTPLETARYHNNPEVALLL 259
Score = 88.2 bits (209), Expect = 9e-17
Identities = 68/200 (34%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L VAA G L+N GA R A+ T LHLAA GH ++LL G +D
Sbjct: 14 LLVAAYKGQTENVVQLINKGA--RVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQ 71
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ QT LH AT+ + E++ L+ + +D DG T LH A G A+LL+
Sbjct: 72 DDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHG--FSQSAKLLVK 129
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
AGA+ A + G T LH+A N S +LL G L+ N G + L R I
Sbjct: 130 AGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSI 189
Query: 402 PRYLCKFDDAVHVSEHELGD 421
R L +VH +++ GD
Sbjct: 190 IRLLLTAFCSVH-EKNQAGD 208
Score = 86.2 bits (204), Expect = 4e-16
Identities = 69/219 (31%), Positives = 99/219 (45%), Gaps = 3/219 (1%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
LI GA V R+PLH A VV+ LL+AG D +T LH A +G+
Sbjct: 29 LINKGARVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNT 88
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ G + G TALH A+ G ++ A+LL+ GA++ N G T LHL
Sbjct: 89 EIIAALIHEGCALDRQDKDGN-TALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHL 147
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
A + +L+ + K+ G T LH + I RLLL+A + +
Sbjct: 148 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLH--VAARYNHLSIIRLLLTAFCSVHEKNQ 205
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G T LH+AA +LL+ G D T+ N G + L
Sbjct: 206 AGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPL 244
Score = 77.8 bits (183), Expect = 1e-13
Identities = 70/251 (27%), Positives = 108/251 (43%), Gaps = 6/251 (2%)
Query: 76 SEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKL 135
S+ + L +L A + G++ + +L+ G + GRT LHL+ G V++
Sbjct: 2 SQQDAVAALSERLLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVVQI 60
Query: 136 LLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVL 194
LL G + D + T LH A + + LI G ++ D + LH A
Sbjct: 61 LLKAGCDLDVQDDGDQ---TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASW 117
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
+ K L++AGA T LH+A + T++LL AG+ G T
Sbjct: 118 HGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGD-T 176
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH+AA H RLLL + N G T LH+A +V ++L++ AD
Sbjct: 177 CLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIV 236
Query: 315 DADGRTPLHGA 325
+ G+TPL A
Sbjct: 237 NNAGQTPLETA 247
Score = 66.1 bits (154), Expect = 4e-10
Identities = 73/269 (27%), Positives = 107/269 (39%), Gaps = 6/269 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G +TA+ A +G + ++ L+ G D D G T LH + G + KLL+ GA+
Sbjct: 74 GDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGAN 133
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVK 202
+ + T A L C S V +L AD+ D + LH A + +++
Sbjct: 134 VLAKNKAGNT-ALHLACQNSHSQSTRVLLLAGSRADLKNNAGD-TCLHVAARYNHLSIIR 191
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL A +T LHVAA+L K+LL AGAD G+ T L A
Sbjct: 192 LLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQ-TPLETARYH 250
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ E A LL + + R L + + D A + + G TP
Sbjct: 251 NNPEVALLLTKAPQVLRFSRGRSLRKKR-ERLKEERRAQSVPRDEVAQSKGSVSAGDTPS 309
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADN 351
V AR + LSA +P A D+
Sbjct: 310 SEQAV--ARKEEAREEFLSASPEPRAKDD 336
>AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein.
Length = 693
Score = 120 bits (289), Expect = 2e-26
Identities = 83/246 (33%), Positives = 121/246 (49%), Gaps = 8/246 (3%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDR 186
G E V L++ GA + T+ TPLH AA+ L V++L+ G D++ D+
Sbjct: 22 GQTENVVQLINKGARV----AVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQ 77
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+ LH A + E++ L+ G D T LH A+ G + KLL+ AGA+V A
Sbjct: 78 TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLA 137
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
G TALHLA ++ H++ R+LL G+ D N G T LH+A L ++ +L+
Sbjct: 138 KNKAGN-TALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLT 196
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
V K+ G T LH A + +A++LL AGAD +N G TPL A +
Sbjct: 197 AFCSVHEKNQAGDTALHVAAALNHK--KVAKILLEAGADTTIVNNAGQTPLETARYHNNP 254
Query: 367 ACVLLL 372
LLL
Sbjct: 255 EVALLL 260
Score = 94.3 bits (224), Expect = 1e-18
Identities = 82/250 (32%), Positives = 113/250 (45%), Gaps = 10/250 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LLK G D D DD +T LH + +VG+ E + L+ G D + T LH A+
Sbjct: 62 LLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGC---ALDRQDKDGNTALHEASW 118
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ GA+V A + + LH A + + + LL AG+ D +T
Sbjct: 119 HGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTC 178
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVAA S +LLL A V G TALH+AA H + A++LL+ GA
Sbjct: 179 LHVAARYNHLSIIRLLLTAFCSVHEKNQAGD-TALHVAAALNHKKVAKILLEAGADTTIV 237
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
N GQTPL A + EV +L + + G TP V AR + LS
Sbjct: 238 NNAGQTPLETARYHNNPEVALLLTKA---PQGSVSAGDTPSSEQAV--ARKEEAREEFLS 292
Query: 342 AGADPNAADN 351
A +P A D+
Sbjct: 293 ASPEPRAKDD 302
Score = 88.2 bits (209), Expect = 9e-17
Identities = 68/200 (34%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L VAA G L+N GA R A+ T LHLAA GH ++LL G +D
Sbjct: 15 LLVAAYKGQTENVVQLINKGA--RVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQ 72
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ QT LH AT+ + E++ L+ + +D DG T LH A G A+LL+
Sbjct: 73 DDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHG--FSQSAKLLVK 130
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
AGA+ A + G T LH+A N S +LL G L+ N G + L R I
Sbjct: 131 AGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSI 190
Query: 402 PRYLCKFDDAVHVSEHELGD 421
R L +VH +++ GD
Sbjct: 191 IRLLLTAFCSVH-EKNQAGD 209
Score = 86.2 bits (204), Expect = 4e-16
Identities = 69/219 (31%), Positives = 99/219 (45%), Gaps = 3/219 (1%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
LI GA V R+PLH A VV+ LL+AG D +T LH A +G+
Sbjct: 30 LINKGARVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNT 89
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
L++ G + G TALH A+ G ++ A+LL+ GA++ N G T LHL
Sbjct: 90 EIIAALIHEGCALDRQDKDGN-TALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHL 148
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
A + +L+ + K+ G T LH + I RLLL+A + +
Sbjct: 149 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLH--VAARYNHLSIIRLLLTAFCSVHEKNQ 206
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G T LH+AA +LL+ G D T+ N G + L
Sbjct: 207 AGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPL 245
Score = 81.4 bits (192), Expect = 1e-14
Identities = 80/284 (28%), Positives = 122/284 (42%), Gaps = 11/284 (3%)
Query: 74 FASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECV 133
F S+ + L +L A + G++ + +L+ G + GRT LHL+ G V
Sbjct: 1 FMSQQDAVAALSERLLVAAYKGQTENVVQLINKGARV-AVTKHGRTPLHLAANKGHLPVV 59
Query: 134 KLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYA 192
++LL G + D + T LH A + + LI G ++ D + LH A
Sbjct: 60 QILLKAGCDLDVQDDGDQ---TALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEA 116
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ K L++AGA T LH+A + T++LL AG+ G
Sbjct: 117 SWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGD 176
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
T LH+AA H RLLL + N G T LH+A +V ++L++ AD
Sbjct: 177 -TCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTT 235
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
+ G+TPL A R ++A LL A P + + G TP
Sbjct: 236 IVNNAGQTPLETA--RYHNNPEVALLLTKA---PQGSVSAGDTP 274
Score = 66.9 bits (156), Expect = 2e-10
Identities = 67/233 (28%), Positives = 96/233 (41%), Gaps = 6/233 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G +TA+ A +G + ++ L+ G D D G T LH + G + KLL+ GA+
Sbjct: 75 GDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGAN 134
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVK 202
+ + T A L C S V +L AD+ D + LH A + +++
Sbjct: 135 VLAKNKAGNT-ALHLACQNSHSQSTRVLLLAGSRADLKNNAGD-TCLHVAARYNHLSIIR 192
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL A +T LHVAA+L K+LL AGAD G+ T L A
Sbjct: 193 LLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQ-TPLETARYH 251
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
+ E A LL G TP +A+ E E + + RAKD
Sbjct: 252 NNPEVALLLTKAP---QGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD 301
>CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein.
Length = 278
Score = 120 bits (288), Expect = 2e-26
Identities = 77/202 (38%), Positives = 114/202 (56%), Gaps = 5/202 (2%)
Query: 185 DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV 244
+R+P+H A +++L+E+GAC + V + TPLH A+ G A C +LLL AGA V
Sbjct: 19 ERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV 78
Query: 245 RAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
A G +T L A G EC +LLL +GA ++ P + +PLH A ++ S E V +L
Sbjct: 79 DARNIDG-STPLCDACASGSIECVKLLLSYGAKVNPPLYTA-SPLHEACMSGSSECVRLL 136
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
+D A++ A D TPLH A R D ++LL+AGA+ NAA T LH AA +
Sbjct: 137 IDVGANLEAHDCHFGTPLHVACAR--EHLDCVKVLLNAGANVNAA-KLHETALHHAAKVK 193
Query: 365 FSACVLLLLDYGGDVTLRTNGG 386
+ +L+++GG++ R N G
Sbjct: 194 NVDLIEMLIEFGGNIYARDNRG 215
Score = 115 bits (276), Expect = 7e-25
Identities = 75/204 (36%), Positives = 113/204 (55%), Gaps = 5/204 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A G+S+ L +L++ G +++ T LH + L G CV+LLL GA
Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV- 78
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKEL 204
D+ +TPL A ++ S+ CVK+L+++GA VN L SPLH A +S + E V+ L
Sbjct: 79 --DARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLL 136
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
++ GA + TPLHVA + C K+LLNAGA+V AA TALH AA+ +
Sbjct: 137 IDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAA--KLHETALHHAAKVKN 194
Query: 265 AECARLLLDHGAHIDWPNFRGQTP 288
+ +L++ G +I + RG+ P
Sbjct: 195 VDLIEMLIEFGGNIYARDNRGKKP 218
Score = 105 bits (251), Expect = 8e-22
Identities = 70/205 (34%), Positives = 113/205 (55%), Gaps = 7/205 (3%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
RT +H + G ++ L++ GA N T TPLH A+ CV++L+A GA
Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVN---QVTVDSITPLHAASLQGQARCVQLLLAAGA 76
Query: 178 DVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
V+A D S PL A S + E VK LL GA + P ++T +PLH A GS+ C +L
Sbjct: 77 QVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPP-LYTASPLHEACMSGSSECVRL 135
Query: 237 LLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQ 296
L++ GA++ A T LH+A H +C ++LL+ GA+++ +T LH A +
Sbjct: 136 LIDVGANLEAH-DCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLH-ETALHHAAKVK 193
Query: 297 SLEVVEMLVDRCADVRAKDADGRTP 321
+++++EML++ ++ A+D G+ P
Sbjct: 194 NVDLIEMLIEFGGNIYARDNRGKKP 218
Score = 39.5 bits (88), Expect = 0.043
Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
RTP+H A RG + + +L+ S GA N TPLH A+L + CV LLL G
Sbjct: 20 RTPVHEAAQRG-ESLQLQQLIES-GACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQ 77
Query: 379 VTLRTNGGVSAL 390
V R G + L
Sbjct: 78 VDARNIDGSTPL 89
>BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH
domain containing 1 protein.
Length = 627
Score = 120 bits (288), Expect = 2e-26
Identities = 95/294 (32%), Positives = 134/294 (45%), Gaps = 5/294 (1%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + KLL +E + G + L L+C G E ++LL H N D
Sbjct: 212 ACSDGDVNAVRKLLDECRSVNEHTEEGESLLCLACSAGYYELAQVLL--AMHANVEDRGN 269
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA 209
+ TPL A+S L VK+L+ H ADVN+ + + L YA ++VK LL GA
Sbjct: 270 KGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGA 329
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ TPL AAS G ++LL+ GA + K +AL LA GH + R
Sbjct: 330 NIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LL+ GA + T L A + +EV +L+D A V +PL A G
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMPADSFESPLTLAACGG 449
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
++A LL+ GA+ ++ GYTPL AA V LLL G ++ +T
Sbjct: 450 --HVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQT 501
Score = 102 bits (244), Expect = 5e-21
Identities = 100/319 (31%), Positives = 148/319 (46%), Gaps = 12/319 (3%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E G G T ++ A G ++ LL D + G T L +C G + VK+L
Sbjct: 265 EDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVL 324
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD--RSPLHYAVL 194
L+ GA+ + E TPL AASA + +VL+ HGA +N ++ S L A
Sbjct: 325 LNEGAN---IEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACY 381
Query: 195 SDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
++V+ LLEAGA + T L A G +LLL++GA V +
Sbjct: 382 KGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNMP-ADSFES 440
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
L LAA GH E A LL++ GA+++ N G TPL A E+V +L+ + A++ A+
Sbjct: 441 PLTLAACGGHVELAALLIERGANLEEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQ 500
Query: 315 DADGR-TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ + T L A G ++A L+ AGAD + TPL A+ V LL
Sbjct: 501 TEETQETALTLACCGG--FSEVADFLIKAGADIELGCS---TPLMEASQEGHLELVKYLL 555
Query: 374 DYGGDVTLRTNGGVSALSF 392
G +V T G +AL++
Sbjct: 556 ASGANVHATTATGDTALTY 574
Score = 102 bits (244), Expect = 5e-21
Identities = 94/296 (31%), Positives = 138/296 (46%), Gaps = 10/296 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ +AC G ++ LL G + ++ ++ G T L + G E ++LLDHGA NT
Sbjct: 307 TALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINT 366
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
S E K + L A L V+ L+ GAD + + L A + EV + L
Sbjct: 367 --HSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLL 424
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L++GA + P E+PL +AA G LL+ GA++ G T L AA +GH
Sbjct: 425 LDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANLEEVNDEG-YTPLMEAAREGH 483
Query: 265 AECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
E LLL GA+I+ Q T L LA EV + L+ AD+ + TPL
Sbjct: 484 EEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADI---ELGCSTPLM 540
Query: 324 GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
A G ++ + LL++GA+ +A G T L A N + +LL G D+
Sbjct: 541 EASQEG--HLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL 594
Score = 87.0 bits (206), Expect = 2e-16
Identities = 84/269 (31%), Positives = 122/269 (45%), Gaps = 7/269 (2%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL 183
+C G V+ LLD N E+ L C+A LA V + + +
Sbjct: 212 ACSDGDVNAVRKLLDECRSVNEHTEEGESLLC-LACSAGYYELAQVLLAMHANVEDRGNK 270
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
D +PL A ++VK LL A ++ T L A + G K+LLN GA+
Sbjct: 271 GDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGAN 330
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW-PNFRGQTPLHLATLAQSLEVVE 302
+ G T L AA GH E AR+LLDHGA I+ N ++ L LA L++V
Sbjct: 331 IEDHNENGH-TPLMEAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVR 389
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN-AADNFGYTPLHIAA 361
L++ AD K + T L A + G ++ARLLL +GA N AD+F +PL +AA
Sbjct: 390 FLLEAGADQEHKTDEMHTALMEACMDGH--VEVARLLLDSGAQVNMPADSF-ESPLTLAA 446
Query: 362 LNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
LL++ G ++ + G + L
Sbjct: 447 CGGHVELAALLIERGANLEEVNDEGYTPL 475
Score = 84.6 bits (200), Expect = 1e-15
Identities = 76/242 (31%), Positives = 113/242 (46%), Gaps = 12/242 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
+A+ AC+ G ++ LL+ G D + D T L +C+ G E +LLLD GA N
Sbjct: 374 SALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALMEACMDGHVEVARLLLDSGAQVNM 433
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKE 203
S E +PL AA + +LI GA++ ++D +PL A E+V
Sbjct: 434 PADSFE---SPLTLAACGGHVELAALLIERGANLEE-VNDEGYTPLMEAAREGHEEMVAL 489
Query: 204 LLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA + T ET L +A G + L+ AGAD+ G +T L A+++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIEL----GCSTPLMEASQE 545
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LL GA++ G T L A +V ++L+ AD+ K D +T L
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVLLQAGADL-DKQEDMKTIL 604
Query: 323 HG 324
G
Sbjct: 605 EG 606
Score = 62.5 bits (145), Expect = 5e-09
Identities = 54/171 (31%), Positives = 85/171 (49%), Gaps = 5/171 (2%)
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH 274
QV T + L A S G + + LL+ V G++ L LA G+ E A++LL
Sbjct: 203 QVDTRS-LAEACSDGDVNAVRKLLDECRSVNEHTEEGESL-LCLACSAGYYELAQVLLAM 260
Query: 275 GAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
A+++ +G TPL A+ L++V++L+ ADV ++ A G T L A G
Sbjct: 261 HANVEDRGNKGDITPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGF--V 318
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
DI ++LL+ GA+ + G+TPL AA +LLD+G + +N
Sbjct: 319 DIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGAGINTHSN 369
>AL365356-2|CAH72614.1| 278|Homo sapiens ankyrin repeat and SOCS
box-containing 13 protein.
Length = 278
Score = 120 bits (288), Expect = 2e-26
Identities = 77/202 (38%), Positives = 114/202 (56%), Gaps = 5/202 (2%)
Query: 185 DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV 244
+R+P+H A +++L+E+GAC + V + TPLH A+ G A C +LLL AGA V
Sbjct: 19 ERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV 78
Query: 245 RAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
A G +T L A G EC +LLL +GA ++ P + +PLH A ++ S E V +L
Sbjct: 79 DARNIDG-STPLCDACASGSIECVKLLLSYGAKVNPPLYTA-SPLHEACMSGSSECVRLL 136
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
+D A++ A D TPLH A R D ++LL+AGA+ NAA T LH AA +
Sbjct: 137 IDVGANLEAHDCHFGTPLHVACAR--EHLDCVKVLLNAGANVNAA-KLHETALHHAAKVK 193
Query: 365 FSACVLLLLDYGGDVTLRTNGG 386
+ +L+++GG++ R N G
Sbjct: 194 NVDLIEMLIEFGGNIYARDNRG 215
Score = 115 bits (276), Expect = 7e-25
Identities = 75/204 (36%), Positives = 113/204 (55%), Gaps = 5/204 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A G+S+ L +L++ G +++ T LH + L G CV+LLL GA
Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV- 78
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKEL 204
D+ +TPL A ++ S+ CVK+L+++GA VN L SPLH A +S + E V+ L
Sbjct: 79 --DARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLL 136
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
++ GA + TPLHVA + C K+LLNAGA+V AA TALH AA+ +
Sbjct: 137 IDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAA--KLHETALHHAAKVKN 194
Query: 265 AECARLLLDHGAHIDWPNFRGQTP 288
+ +L++ G +I + RG+ P
Sbjct: 195 VDLIEMLIEFGGNIYARDNRGKKP 218
Score = 105 bits (251), Expect = 8e-22
Identities = 70/205 (34%), Positives = 113/205 (55%), Gaps = 7/205 (3%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
RT +H + G ++ L++ GA N T TPLH A+ CV++L+A GA
Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVN---QVTVDSITPLHAASLQGQARCVQLLLAAGA 76
Query: 178 DVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
V+A D S PL A S + E VK LL GA + P ++T +PLH A GS+ C +L
Sbjct: 77 QVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPP-LYTASPLHEACMSGSSECVRL 135
Query: 237 LLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQ 296
L++ GA++ A T LH+A H +C ++LL+ GA+++ +T LH A +
Sbjct: 136 LIDVGANLEAH-DCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLH-ETALHHAAKVK 193
Query: 297 SLEVVEMLVDRCADVRAKDADGRTP 321
+++++EML++ ++ A+D G+ P
Sbjct: 194 NVDLIEMLIEFGGNIYARDNRGKKP 218
Score = 39.5 bits (88), Expect = 0.043
Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
RTP+H A RG + + +L+ S GA N TPLH A+L + CV LLL G
Sbjct: 20 RTPVHEAAQRG-ESLQLQQLIES-GACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQ 77
Query: 379 VTLRTNGGVSAL 390
V R G + L
Sbjct: 78 VDARNIDGSTPL 89
>Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein
protein.
Length = 1119
Score = 119 bits (287), Expect = 3e-26
Identities = 96/299 (32%), Positives = 146/299 (48%), Gaps = 20/299 (6%)
Query: 112 ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKV 171
E+DD G T LH + E VK LL GA+PN + + PLH A + +KV
Sbjct: 93 EMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNM---MAPLHIAVQGMNNEVMKV 149
Query: 172 LIAHGA-DVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLG 229
L+ H DVN G + + + A ++ E ++ LL GA P + P+H AA G
Sbjct: 150 LLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLNKGAKPCKSNKWGCFPIHQAAFSG 209
Query: 230 SASCTKLLLNAGADVRAA-------MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
S C +++L G + + M GKAT LHLA ++G E ++ LD+GA ID P
Sbjct: 210 SKECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQID-PV 268
Query: 283 FRGQ-TPLHLATLAQSLEVVEMLVDRCAD----VRAKDADGRTPLHGAIVRGARACDIAR 337
+G+ T +H A + E+V++++ + V D T LH A + ++A
Sbjct: 269 EKGRCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHH--ELAD 326
Query: 338 LLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
L+S GAD N D+ G +PL +A + V LLL G V ++ N G + L V++
Sbjct: 327 YLISVGADINKIDSEGRSPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQ 385
Score = 93.1 bits (221), Expect = 3e-18
Identities = 101/366 (27%), Positives = 158/366 (43%), Gaps = 27/366 (7%)
Query: 71 TIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSE 130
TI E E G TA++ AC S L LL G P + + G +H + GS+
Sbjct: 155 TIDVNLEGENG---NTAVIIACTTNNSEALQILLNKGAKPCKSNKWGCFPIHQAAFSGSK 211
Query: 131 ECVKLLL----DHG-AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
EC++++L +HG + + KATPLH A L +K+ + +GA ++
Sbjct: 212 ECMEIILRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKG 271
Query: 186 R-SPLHYAVLSDAPEVVKELLE--AGACP--DTPQVFTETPLHVAASLGSASCTKLLLNA 240
R + +H+A A E+VK ++ +G+ +T ET LH A+ L++
Sbjct: 272 RCTAIHFAATQGATEIVKLMISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISV 331
Query: 241 GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL----AQ 296
GAD+ G+ + L LA LLL GA +D + G+ LHL +
Sbjct: 332 GADINKIDSEGR-SPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPYGLK 390
Query: 297 SLEVVEMLVDRCAD-VRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+L M + + + V +D DG TPLH A +G LL ++ +
Sbjct: 391 NLRPEFMQMQQIKELVMDEDNDGCTPLHYACRQGGPGS--VNNLLGFNVSIHSKSKDKKS 448
Query: 356 PLHIAA-LNEFSACVLLLLDYGGDVTLRTNG---GVSALSFIVRRVPDVIPRYLCKFDDA 411
PLH AA + C LL D D L G G++ L + D + + L K A
Sbjct: 449 PLHFAASYGRINTCQRLLQDI-SDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLLLK-KGA 506
Query: 412 VHVSEH 417
+ +S+H
Sbjct: 507 LFLSDH 512
Score = 69.7 bits (163), Expect = 3e-11
Identities = 46/157 (29%), Positives = 77/157 (49%), Gaps = 4/157 (2%)
Query: 222 LHVAASLGSASCT-KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
LH AA+ G K+ ++ +V M T LH A E E + LL GA+ +
Sbjct: 67 LHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNL 126
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVD-RCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
NF PLH+A + EV+++L++ R DV + +G T + I + ++L
Sbjct: 127 RNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAV--IIACTTNNSEALQIL 184
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
L+ GA P ++ +G P+H AA + C+ ++L +G
Sbjct: 185 LNKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFG 221
Score = 69.3 bits (162), Expect = 5e-11
Identities = 90/339 (26%), Positives = 138/339 (40%), Gaps = 25/339 (7%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D T LH + L E L+ GA N DS + PL A ++ S V +L+
Sbjct: 306 DGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRS---PLILATASASWNIVNLLL 362
Query: 174 AHGADVNAGLS-DRSPLH------YAVLSDAPEVVK--ELLEAGACPDTPQVFTETPLHV 224
+ GA V+ + R+ LH Y + + PE ++ ++ E D TPLH
Sbjct: 363 SKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMDEDNDGC---TPLHY 419
Query: 225 AASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAH--IDWP 281
A G LL + + K + LH AA G C RLL D ++
Sbjct: 420 ACRQGGPGSVNNLLGFNVSIHSK-SKDKKSPLHFAASYGRINTCQRLLQDISDTRLLNEG 478
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ G TPLHLA +VV++L+ + A + D +G T LH A + G +++L
Sbjct: 479 DLHGMTPLHLAAKNGHDKVVQLLLKKGA-LFLSDHNGWTALHHASMGGYT--QTMKVILD 535
Query: 342 AGAD-PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL-RTNGGVSALSFIVRRVPD 399
+ D G T LH AA + V LLL + D+ L + L+ +R
Sbjct: 536 TNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNADIVLNKQQASFLHLALHNKRKEV 595
Query: 400 VIPRYLCK-FDDAVHVSEHELGDVDCELTIDFRPLVPCL 437
V+ K +D+ + + H C +T L C+
Sbjct: 596 VLTIIRSKRWDECLKIFSHNSPGNKCPITEMIEYLPECM 634
Score = 66.5 bits (155), Expect = 3e-10
Identities = 35/146 (23%), Positives = 65/146 (44%), Gaps = 1/146 (0%)
Query: 469 QHDVAAITIFFCWLELMMIIGRFPTFGLYVQMFTTVTVNFATFLLAYSCLLIAFGLAFSV 528
Q AI ++F W+ ++ + RF G+++ M + + + LL+AFGL+F +
Sbjct: 831 QWQCGAIAVYFYWMNFLLYLQRFENCGIFIVMLEVILKTLLRSTVVFIFLLLAFGLSFYI 890
Query: 529 LFSNYPAFHLP-AGLVKTVMMMSGELEYEDIFYNNCTNSEIYYPLTAHIMXXXXXXXXXX 587
L + F P +++T MM G++ Y + F +E+ +P+ +
Sbjct: 891 LLNLQDPFSSPLLSIIQTFSMMLGDINYRESFLEPYLRNELAHPVLSFAQLVSFTIFVPI 950
Query: 588 XXXXXXXXXAVSDIQALQEGAGLDRL 613
AV DI +Q+ A L R+
Sbjct: 951 VLMNLLIGLAVGDIAEVQKHASLKRI 976
>AF403031-1|AAL57350.1| 286|Homo sapiens ankyrin repeat
domain-containing SOCS box protein Asb-13 protein.
Length = 286
Score = 118 bits (284), Expect = 8e-26
Identities = 76/202 (37%), Positives = 113/202 (55%), Gaps = 5/202 (2%)
Query: 185 DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV 244
+R+P+H A +++L+E+GAC + V + TPLH A+ G A C +LLL AGA V
Sbjct: 27 ERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV 86
Query: 245 RAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
A G +T L A G EC +LLL +GA ++ P + +PLH A ++ E V +L
Sbjct: 87 DARNIDG-STPLCDACASGSIECVKLLLSYGAKVNPPLYTA-SPLHEACMSGDSECVRLL 144
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
+D A++ A D TPLH A R D ++LL+AGA+ NAA T LH AA +
Sbjct: 145 IDVGANLEAHDCHFGTPLHVACAR--EHLDCVKVLLNAGANVNAA-KLHETALHHAAKVK 201
Query: 365 FSACVLLLLDYGGDVTLRTNGG 386
+ +L+++GG++ R N G
Sbjct: 202 NVDLIEMLIEFGGNIYARDNRG 223
Score = 113 bits (273), Expect = 2e-24
Identities = 75/204 (36%), Positives = 112/204 (54%), Gaps = 5/204 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A G+S+ L +L++ G +++ T LH + L G CV+LLL GA
Sbjct: 28 RTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV- 86
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKEL 204
D+ +TPL A ++ S+ CVK+L+++GA VN L SPLH A +S E V+ L
Sbjct: 87 --DARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGDSECVRLL 144
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
++ GA + TPLHVA + C K+LLNAGA+V AA TALH AA+ +
Sbjct: 145 IDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAA--KLHETALHHAAKVKN 202
Query: 265 AECARLLLDHGAHIDWPNFRGQTP 288
+ +L++ G +I + RG+ P
Sbjct: 203 VDLIEMLIEFGGNIYARDNRGKKP 226
Score = 103 bits (247), Expect = 2e-21
Identities = 69/205 (33%), Positives = 112/205 (54%), Gaps = 7/205 (3%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
RT +H + G ++ L++ GA N T TPLH A+ CV++L+A GA
Sbjct: 28 RTPVHEAAQRGESLQLQQLIESGACVN---QVTVDSITPLHAASLQGQARCVQLLLAAGA 84
Query: 178 DVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
V+A D S PL A S + E VK LL GA + P ++T +PLH A G + C +L
Sbjct: 85 QVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPP-LYTASPLHEACMSGDSECVRL 143
Query: 237 LLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQ 296
L++ GA++ A T LH+A H +C ++LL+ GA+++ +T LH A +
Sbjct: 144 LIDVGANLEAH-DCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLH-ETALHHAAKVK 201
Query: 297 SLEVVEMLVDRCADVRAKDADGRTP 321
+++++EML++ ++ A+D G+ P
Sbjct: 202 NVDLIEMLIEFGGNIYARDNRGKKP 226
Score = 39.5 bits (88), Expect = 0.043
Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
RTP+H A RG + + +L+ S GA N TPLH A+L + CV LLL G
Sbjct: 28 RTPVHEAAQRG-ESLQLQQLIES-GACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQ 85
Query: 379 VTLRTNGGVSAL 390
V R G + L
Sbjct: 86 VDARNIDGSTPL 97
>BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein.
Length = 1672
Score = 117 bits (282), Expect = 1e-25
Identities = 98/313 (31%), Positives = 145/313 (46%), Gaps = 11/313 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA++ A G ++ +LLK GV+ + D G T L +C G + V+LLL HGA+P+
Sbjct: 31 TALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSV 90
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVK 202
+ P+ AA V +L+ +GA VN SD+ +PL +A E VK
Sbjct: 91 ---TGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNC--SDKYGTTPLVWAARKGHLECVK 145
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA D + T L VA G K +L +V G TAL +A+++
Sbjct: 146 HLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGN-TALMIASKE 204
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LLD G +++ P+ G T L A +E+V L+ + AD+ + D +T L
Sbjct: 205 GHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTAL 264
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
+ A+ +G + R +L D G TPL A V LLLD G V+
Sbjct: 265 YWAVEKG--NATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAV 322
Query: 383 TNGGVSALSFIVR 395
G + L +R
Sbjct: 323 DKKGDTPLHIAIR 335
Score = 103 bits (248), Expect = 2e-21
Identities = 93/289 (32%), Positives = 127/289 (43%), Gaps = 7/289 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA++WAC+ G++ ++ LL G +P + + G + V LLL +GA N
Sbjct: 64 TALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNC 123
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
D + TPL AA L CVK L+A GADV+ G + + L AV + VKE+
Sbjct: 124 SD---KYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEI 180
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ + T L +A+ G + LL+AG V G T L A GH
Sbjct: 181 LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGD-TVLIGAVRGGH 239
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
E R LL A ID +T L+ A + +V ++ D DG TPL
Sbjct: 240 VEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIK 299
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
A R ++ LLL GA +A D G TPLHIA LLL
Sbjct: 300 ATKM--RNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLL 346
Score = 69.7 bits (163), Expect = 3e-11
Identities = 67/230 (29%), Positives = 101/230 (43%), Gaps = 9/230 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++WA G + LL MG D D+ T L ++ G + VK +L + N
Sbjct: 130 TPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNL 189
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP---LHYAVLSDAPEVVK 202
D T L A+ V+ L+ G VN + DRS L AV E+V+
Sbjct: 190 TDKDGNTA---LMIASKEGHTEIVQDLLDAGTYVN--IPDRSGDTVLIGAVRGGHVEIVR 244
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL+ A D +T L+ A G+A+ + +L D G+ T L A +
Sbjct: 245 ALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGE-TPLIKATKM 303
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
+ E LLLD GA + + +G TPLH+A +S ++ E+L+ D R
Sbjct: 304 RNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGR 353
Score = 66.5 bits (155), Expect = 3e-10
Identities = 65/218 (29%), Positives = 106/218 (48%), Gaps = 14/218 (6%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G TA++ A G + + ++LK + + D G T L ++ G E V+ LLD G
Sbjct: 158 GANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 217
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPE 199
+ N D S + T L A + V+ L+ AD++ G +++ L++AV
Sbjct: 218 TYVNIPDRSGD---TVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNAT 274
Query: 200 VVKELLEAGACPDTPQVFT---ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
+V+++L+ PDT ++ T ETPL A + + +LLL+ GA V A G T L
Sbjct: 275 MVRDILQCN--PDT-EICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGD-TPL 330
Query: 257 HLAAEDGHAECARLLLDH---GAHIDWPNFRGQTPLHL 291
H+A + A LLL + G + PN G+TP ++
Sbjct: 331 HIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNI 368
Score = 61.7 bits (143), Expect = 9e-09
Identities = 55/192 (28%), Positives = 81/192 (42%), Gaps = 3/192 (1%)
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
E+VKEL++ GA + + T L A+ G + LL G ++ G TAL
Sbjct: 10 EIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLE-HRDMGGWTALMW 68
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
A G + LLL HGA+ P+ A ++V +L+ A V D G
Sbjct: 69 ACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYG 128
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
TPL A +G C + LL+ GAD + T L +A ++ V +L +
Sbjct: 129 TTPLVWAARKGHLEC--VKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPN 186
Query: 379 VTLRTNGGVSAL 390
V L G +AL
Sbjct: 187 VNLTDKDGNTAL 198
Score = 53.6 bits (123), Expect = 2e-06
Identities = 40/139 (28%), Positives = 65/139 (46%), Gaps = 2/139 (1%)
Query: 258 LAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
+AAE G+ E + L+ +GA+ + + T L A+ + +VE L+ ++ +D
Sbjct: 2 IAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMG 61
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G T L A +G D+ LLLS GA+P+ + P+ AA + V LLL G
Sbjct: 62 GWTALMWACYKG--RTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGA 119
Query: 378 DVTLRTNGGVSALSFIVRR 396
V G + L + R+
Sbjct: 120 KVNCSDKYGTTPLVWAARK 138
>AK023196-1|BAB14456.1| 278|Homo sapiens ARPP-19) mRNA. protein.
Length = 278
Score = 117 bits (282), Expect = 1e-25
Identities = 76/202 (37%), Positives = 113/202 (55%), Gaps = 5/202 (2%)
Query: 185 DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV 244
+R+P+H A +++L+E+GAC + V + TPLH A+ G A C +LLL AGA V
Sbjct: 19 ERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV 78
Query: 245 RAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
A G +T L A G EC +L L +GA ++ P + +PLH A ++ S E V +L
Sbjct: 79 DARNIDG-STPLCDACASGSIECVKLSLSYGAKVNPPLYTA-SPLHEACMSGSSECVRLL 136
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
+D A++ A D TPLH A R D ++LL+AGA+ NAA T LH AA +
Sbjct: 137 IDVGANLEAHDCHFGTPLHVACAR--EHLDCVKVLLNAGANVNAA-KLHETALHHAAKVK 193
Query: 365 FSACVLLLLDYGGDVTLRTNGG 386
+ +L+++GG++ R N G
Sbjct: 194 NVDLIEMLIEFGGNIYARDNRG 215
Score = 112 bits (270), Expect = 4e-24
Identities = 74/204 (36%), Positives = 112/204 (54%), Gaps = 5/204 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A G+S+ L +L++ G +++ T LH + L G CV+LLL GA
Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV- 78
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKEL 204
D+ +TPL A ++ S+ CVK+ +++GA VN L SPLH A +S + E V+ L
Sbjct: 79 --DARNIDGSTPLCDACASGSIECVKLSLSYGAKVNPPLYTASPLHEACMSGSSECVRLL 136
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
++ GA + TPLHVA + C K+LLNAGA+V AA TALH AA+ +
Sbjct: 137 IDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAA--KLHETALHHAAKVKN 194
Query: 265 AECARLLLDHGAHIDWPNFRGQTP 288
+ +L++ G +I + RG+ P
Sbjct: 195 VDLIEMLIEFGGNIYARDNRGKKP 218
Score = 102 bits (245), Expect = 4e-21
Identities = 69/205 (33%), Positives = 112/205 (54%), Gaps = 7/205 (3%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
RT +H + G ++ L++ GA N T TPLH A+ CV++L+A GA
Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVN---QVTVDSITPLHAASLQGQARCVQLLLAAGA 76
Query: 178 DVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
V+A D S PL A S + E VK L GA + P ++T +PLH A GS+ C +L
Sbjct: 77 QVDARNIDGSTPLCDACASGSIECVKLSLSYGAKVNPP-LYTASPLHEACMSGSSECVRL 135
Query: 237 LLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQ 296
L++ GA++ A T LH+A H +C ++LL+ GA+++ +T LH A +
Sbjct: 136 LIDVGANLEAH-DCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLH-ETALHHAAKVK 193
Query: 297 SLEVVEMLVDRCADVRAKDADGRTP 321
+++++EML++ ++ A+D G+ P
Sbjct: 194 NVDLIEMLIEFGGNIYARDNRGKKP 218
Score = 39.5 bits (88), Expect = 0.043
Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
RTP+H A RG + + +L+ S GA N TPLH A+L + CV LLL G
Sbjct: 20 RTPVHEAAQRG-ESLQLQQLIES-GACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQ 77
Query: 379 VTLRTNGGVSAL 390
V R G + L
Sbjct: 78 VDARNIDGSTPL 89
>AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein.
Length = 1777
Score = 117 bits (282), Expect = 1e-25
Identities = 98/313 (31%), Positives = 145/313 (46%), Gaps = 11/313 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA++ A G ++ +LLK GV+ + D G T L +C G + V+LLL HGA+P+
Sbjct: 79 TALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSV 138
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVK 202
+ P+ AA V +L+ +GA VN SD+ +PL +A E VK
Sbjct: 139 ---TGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNC--SDKYGTTPLVWAARKGHLECVK 193
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL GA D + T L VA G K +L +V G TAL +A+++
Sbjct: 194 HLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGN-TALMIASKE 252
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
GH E + LLD G +++ P+ G T L A +E+V L+ + AD+ + D +T L
Sbjct: 253 GHTEIVQDLLDAGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTAL 312
Query: 323 HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLR 382
+ A+ +G + R +L D G TPL A V LLLD G V+
Sbjct: 313 YWAVEKG--NATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAV 370
Query: 383 TNGGVSALSFIVR 395
G + L +R
Sbjct: 371 DKKGDTPLHIAIR 383
Score = 103 bits (248), Expect = 2e-21
Identities = 93/289 (32%), Positives = 127/289 (43%), Gaps = 7/289 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA++WAC+ G++ ++ LL G +P + + G + V LLL +GA N
Sbjct: 112 TALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNC 171
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
D + TPL AA L CVK L+A GADV+ G + + L AV + VKE+
Sbjct: 172 SD---KYGTTPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEI 228
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L+ + T L +A+ G + LL+AG V G T L A GH
Sbjct: 229 LKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNIPDRSGD-TVLIGAVRGGH 287
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
E R LL A ID +T L+ A + +V ++ D DG TPL
Sbjct: 288 VEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIK 347
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
A R ++ LLL GA +A D G TPLHIA LLL
Sbjct: 348 ATKM--RNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLL 394
Score = 94.7 bits (225), Expect = 1e-18
Identities = 89/295 (30%), Positives = 131/295 (44%), Gaps = 7/295 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ D DE ++ G+T L ++ G+ E VK L+ +GA+ N D T L A+
Sbjct: 30 LLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLD---NWTALISASK 86
Query: 163 AKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V+ L+ G ++ + + + L +A +VV+ LL GA P +++ P
Sbjct: 87 EGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYP 146
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+ AA G A LLL GA V + G T L AA GH EC + LL GA +D
Sbjct: 147 IIWAAGRGHADIVHLLLQNGAKVNCSDKYG-TTPLVWAARKGHLECVKHLLAMGADVDQE 205
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
T L +A + V+ ++ R +V D DG T L A G +I + LL
Sbjct: 206 GANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEG--HTEIVQDLLD 263
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
AG N D G T L A V LL D+ +R +AL + V +
Sbjct: 264 AGTYVNIPDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEK 318
Score = 75.8 bits (178), Expect = 5e-13
Identities = 66/213 (30%), Positives = 93/213 (43%), Gaps = 4/213 (1%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
L +S ++Y + P +K LLE D +TPL +AA G+ K L+ GA
Sbjct: 10 LISQSVINYVEEENIP-ALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGA 68
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+ TAL A+++GH LL G +++ + G T L A +VVE
Sbjct: 69 NCNLE-DLDNWTALISASKEGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVE 127
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
+L+ A+ P+ A RG DI LLL GA N +D +G TPL AA
Sbjct: 128 LLLSHGANPSVTGLYSVYPIIWAAGRG--HADIVHLLLQNGAKVNCSDKYGTTPLVWAAR 185
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
CV LL G DV ++AL V+
Sbjct: 186 KGHLECVKHLLAMGADVDQEGANSMTALIVAVK 218
Score = 69.7 bits (163), Expect = 3e-11
Identities = 67/230 (29%), Positives = 101/230 (43%), Gaps = 9/230 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++WA G + LL MG D D+ T L ++ G + VK +L + N
Sbjct: 178 TPLVWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNL 237
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP---LHYAVLSDAPEVVK 202
D T L A+ V+ L+ G VN + DRS L AV E+V+
Sbjct: 238 TDKDGNTA---LMIASKEGHTEIVQDLLDAGTYVN--IPDRSGDTVLIGAVRGGHVEIVR 292
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LL+ A D +T L+ A G+A+ + +L D G+ T L A +
Sbjct: 293 ALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGE-TPLIKATKM 351
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
+ E LLLD GA + + +G TPLH+A +S ++ E+L+ D R
Sbjct: 352 RNIEVVELLLDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGR 401
Score = 66.5 bits (155), Expect = 3e-10
Identities = 65/218 (29%), Positives = 106/218 (48%), Gaps = 14/218 (6%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G TA++ A G + + ++LK + + D G T L ++ G E V+ LLD G
Sbjct: 206 GANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAG 265
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPE 199
+ N D S + T L A + V+ L+ AD++ G +++ L++AV
Sbjct: 266 TYVNIPDRSGD---TVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNAT 322
Query: 200 VVKELLEAGACPDTPQVFT---ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
+V+++L+ PDT ++ T ETPL A + + +LLL+ GA V A G T L
Sbjct: 323 MVRDILQCN--PDT-EICTKDGETPLIKATKMRNIEVVELLLDKGAKVSAVDKKGD-TPL 378
Query: 257 HLAAEDGHAECARLLLDH---GAHIDWPNFRGQTPLHL 291
H+A + A LLL + G + PN G+TP ++
Sbjct: 379 HIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNI 416
Score = 56.8 bits (131), Expect = 3e-07
Identities = 48/162 (29%), Positives = 74/162 (45%), Gaps = 3/162 (1%)
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL 294
K LL DV G+ T L +AAE G+ E + L+ +GA+ + + T L A+
Sbjct: 28 KALLEKCKDVDERNECGQ-TPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASK 86
Query: 295 AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGY 354
+ +VE L+ ++ +D G T L A +G D+ LLLS GA+P+ +
Sbjct: 87 EGHVHIVEELLKCGVNLEHRDMGGWTALMWACYKG--RTDVVELLLSHGANPSVTGLYSV 144
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
P+ AA + V LLL G V G + L + R+
Sbjct: 145 YPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPLVWAARK 186
>BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein.
Length = 725
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a
protein.
Length = 1065
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDQEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDQEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 57.2 bits (132), Expect = 2e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDQEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDQE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin
protein.
Length = 604
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein.
Length = 895
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein.
Length = 1065
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein.
Length = 895
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein
alternative isoform protein.
Length = 895
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein.
Length = 1065
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 256 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 311
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 312 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 370
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 371 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 429
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 430 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 489
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 490 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 547
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 218 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 276 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 335
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 336 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 395
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 396 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 453
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 454 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 493
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 82 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 140
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 141 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 198
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 199 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 258
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 259 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 318
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 319 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 376
Query: 373 LDYGGDV 379
L+ V
Sbjct: 377 LENNAQV 383
Score = 82.2 bits (194), Expect = 6e-15
Identities = 75/261 (28%), Positives = 121/261 (46%), Gaps = 18/261 (6%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ E FG RT +++ + LLK G D ++ D + RT LHL+ G+ +KLL
Sbjct: 42 DKEDQFG-RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLL 100
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAV 193
L A+ W + TPLH +S C+ +L+ A D+ + LH++
Sbjct: 101 LTRRAN---WMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSA 157
Query: 194 LSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC---TKLLLNAGADVRAAMG- 249
+ PE VK L++ + P V + PLH AA+ S + +L+A A + +
Sbjct: 158 YYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDA-APTESLLNW 216
Query: 250 ---PGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G+ T LH A DG+ +L + +I + +TPLH A L ++V +L+
Sbjct: 217 QDYEGR-TPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLL 275
Query: 306 DR-CADVRAKDADGRTPLHGA 325
+R + D+ G TPLH A
Sbjct: 276 ERNKSGTIPSDSQGATPLHYA 296
Score = 72.1 bits (169), Expect = 7e-12
Identities = 61/196 (31%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
R+PL Y VL+D + LL+AGA + T LH+AA G+ KLLL A+
Sbjct: 49 RTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN-W 107
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGA--HIDWPNFRGQTPLHLATLAQSLEVVEM 303
+ T LHL +C LLL A +D + QT LH + + E V++
Sbjct: 108 MQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKL 167
Query: 304 LVDRCADVRAKDADGRTPLH-GAIVRGARACDIARLLLSAGADP---NAADNFGYTPLHI 359
L+ +++ D +G+ PLH A + A R +L A N D G TPLH
Sbjct: 168 LIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHF 227
Query: 360 AALNEFSACVLLLLDY 375
A + V +L Y
Sbjct: 228 AVADGNVTVVDVLTSY 243
Score = 65.7 bits (153), Expect = 6e-10
Identities = 56/184 (30%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAG-ACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
AG S S +H A ++ ++ L+ A D F TPL C LL
Sbjct: 10 AGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLK 69
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
AGADV + TALHLAA+ G+ +LLL A+ + TPLHL T +S +
Sbjct: 70 AGADVNKT-DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPK 128
Query: 300 VVEMLVDRCA--DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ +L+ A +V +D + +T LH + + +LL+ ++ D G PL
Sbjct: 129 CLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNP--EHVKLLIKHDSNIGIPDVEGKIPL 186
Query: 358 HIAA 361
H AA
Sbjct: 187 HWAA 190
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 457 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 516
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 517 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 556
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 429 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 488
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 489 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 545
Query: 207 AGA 209
GA
Sbjct: 546 HGA 548
Score = 47.2 bits (107), Expect = 2e-04
Identities = 44/191 (23%), Positives = 74/191 (38%), Gaps = 1/191 (0%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+H AA G + L+ + ++ T L +CA LL GA ++
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ +T LHLA + +++L+ R A+ KD + TPLH + C L
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFM 137
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIV-RRVPDV 400
A + + D T LH +A V LL+ + ++ + G L + + P
Sbjct: 138 APGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSA 197
Query: 401 IPRYLCKFDDA 411
+ C D A
Sbjct: 198 VHTVRCILDAA 208
>AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog
protein.
Length = 1013
Score = 116 bits (280), Expect = 2e-25
Identities = 92/300 (30%), Positives = 141/300 (47%), Gaps = 16/300 (5%)
Query: 85 RTAILWACWLGKSILLFKLL---KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
RT + WA LG + ++ LL K G P D G T LH + E VK+ L H
Sbjct: 204 RTPLHWAALLGHAQIVHLLLERNKSGTIPS--DSQGATPLHYAAQSNFAETVKVFLKH-- 259
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAP 198
P+ D S T AA S ++ +++ +D++ ++D+ + LH A LS
Sbjct: 260 -PSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHV 318
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
VK LLE A D V TPL A +G + L+ GA V G + LH
Sbjct: 319 STVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSL-LHW 377
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA G+A+ ++L+++ + + ++ G+TPL A + + +L++ AD +D +G
Sbjct: 378 AALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEG 437
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADN--FGYTPLHIAALNEFSACVLLLLDYG 376
RT LH + G D +LLL A PN +N YTPL A L E + +L++G
Sbjct: 438 RTALHWSCNNG--YLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHG 495
Score = 109 bits (261), Expect = 5e-23
Identities = 83/280 (29%), Positives = 126/280 (45%), Gaps = 7/280 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D GRT LH + G+ V +L + + T S TPLH AA V +L+
Sbjct: 166 DYEGRTPLHFAVADGNVTVVDVLTSYESCNIT--SYDNLFRTPLHWAALLGHAQIVHLLL 223
Query: 174 AHGAD--VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
+ + +PLHYA S+ E VK L+ + D + T AA GS
Sbjct: 224 ERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSD 283
Query: 232 SCTKLLLNAGADVRAAMGPGKA-TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLH 290
+ +L+ +D+ M TALH AA GH +LLL++ A +D + TPL
Sbjct: 284 DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLF 343
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A +V++ L+ A V D DG + LH A + G D+ ++L+ +PN D
Sbjct: 344 RACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGG--NADVCQILIENKINPNVQD 401
Query: 351 NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
G TPL AA + C+ +L++ D ++ G +AL
Sbjct: 402 YAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTAL 441
Score = 95.9 bits (228), Expect = 5e-19
Identities = 95/307 (30%), Positives = 138/307 (44%), Gaps = 17/307 (5%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A G + LL + + D T LHL+ S +C+ LLL A P
Sbjct: 30 RTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMA-PG 88
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVV 201
D+ + K T LH +A + VK+LI H D N G+ D + PLH+A P V
Sbjct: 89 EVDTQDKNKQTALHWSAYYNNPEHVKLLIKH--DSNIGIPDVEGKIPLHWAANHKDPSAV 146
Query: 202 KE---LLEAGACPDT---PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+L+A TPLH A + G+ + +L + + + T
Sbjct: 147 HTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTP 206
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPN-FRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
LH AA GHA+ LLL+ P+ +G TPLH A + E V++ + +
Sbjct: 207 LHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDS 266
Query: 315 DADGRTPLHGAIVRGARACDIARLLLS--AGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D +GRT A +G+ D+ R +LS + D N AD +G T LH AAL+ + V LL
Sbjct: 267 DLEGRTSFMWAAGKGSD--DVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLL 324
Query: 373 LDYGGDV 379
L+ V
Sbjct: 325 LENNAQV 331
Score = 80.6 bits (190), Expect = 2e-14
Identities = 74/245 (30%), Positives = 107/245 (43%), Gaps = 11/245 (4%)
Query: 157 LHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
++C A L C L+ GADVN S R+ LH A +K LL A
Sbjct: 1 MYCVL-ADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKD 59
Query: 216 VFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAAEDGHAECARLLLDH 274
+ TPLH+ S C LLL A K TALH +A + E +LL+ H
Sbjct: 60 LEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKH 119
Query: 275 GAHIDWPNFRGQTPLHLATL---AQSLEVVEMLVDRCAD---VRAKDADGRTPLHGAIVR 328
++I P+ G+ PLH A ++ V ++D + +D +GRTPLH A+
Sbjct: 120 DSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVAD 179
Query: 329 GARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG-GV 387
G + L + + DN TPLH AAL + V LLL+ T+ ++ G
Sbjct: 180 G-NVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGA 238
Query: 388 SALSF 392
+ L +
Sbjct: 239 TPLHY 243
Score = 80.2 bits (189), Expect = 2e-14
Identities = 70/235 (29%), Positives = 111/235 (47%), Gaps = 17/235 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LLK G D ++ D + RT LHL+ G+ +KLLL A+ W + TPLH
Sbjct: 15 LLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRAN---WMQKDLEEMTPLHLTTR 71
Query: 163 AKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
+S C+ +L+ A D+ + LH++ + PE VK L++ + P V +
Sbjct: 72 HRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGK 131
Query: 220 TPLHVAASLGSASC---TKLLLNAGADVRAAMG----PGKATALHLAAEDGHAECARLLL 272
PLH AA+ S + +L+A A + + G+ T LH A DG+ +L
Sbjct: 132 IPLHWAANHKDPSAVHTVRCILDA-APTESLLNWQDYEGR-TPLHFAVADGNVTVVDVLT 189
Query: 273 DH-GAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDR-CADVRAKDADGRTPLHGA 325
+ +I + +TPLH A L ++V +L++R + D+ G TPLH A
Sbjct: 190 SYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYA 244
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/101 (33%), Positives = 52/101 (51%), Gaps = 1/101 (0%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A + G + L++ DP+ D GRT LH SC G + +KLLLD A PN
Sbjct: 405 RTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPN 464
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD 185
+++ E + TPL A + ++ ++ HGA A + D
Sbjct: 465 QMENN-EERYTPLDYALLGERHEVIQFMLEHGALSIAAIQD 504
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/123 (30%), Positives = 63/123 (51%), Gaps = 6/123 (4%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA G + + L++ ++P+ D AGRT L + G C+ +L+++ A PN D
Sbjct: 377 WAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKE 436
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLE 206
T LH + + L +K+L+ A N ++ +PL YA+L + EV++ +LE
Sbjct: 437 GRTA---LHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLE 493
Query: 207 AGA 209
GA
Sbjct: 494 HGA 496
Score = 45.2 bits (102), Expect = 9e-04
Identities = 37/147 (25%), Positives = 61/147 (41%), Gaps = 1/147 (0%)
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+CA LL GA ++ + +T LHLA + +++L+ R A+ KD + TPLH
Sbjct: 10 DCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLT 69
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNG 385
+ C L A + + D T LH +A V LL+ + ++ +
Sbjct: 70 TRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVE 129
Query: 386 GVSALSFIV-RRVPDVIPRYLCKFDDA 411
G L + + P + C D A
Sbjct: 130 GKIPLHWAANHKDPSAVHTVRCILDAA 156
>AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase 2
protein.
Length = 1166
Score = 113 bits (272), Expect = 2e-24
Identities = 93/264 (35%), Positives = 122/264 (46%), Gaps = 27/264 (10%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACP 211
++TPLH AA ++ V+ L+ HGADV+A PLH A EV + L++ GA
Sbjct: 526 QSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVV 585
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ ++ TPLH AA+ G KLLL GAD G T L L +DG + LL
Sbjct: 586 NVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN-TPLDLV-KDGDTDIQDLL 643
Query: 272 LDHGAHIDWPNF----------------------RGQTPLHLATLAQSLEVVEMLVDRCA 309
A +D R TPLHLA +LEV E L+ A
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
DV A+D G PLH A G D+A LL+ A NA D + +TPLH AA +
Sbjct: 704 DVNAQDKGGLIPLHNAASYGH--VDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLC 761
Query: 370 LLLLDYGGDVTLRTNGGVSALSFI 393
LLL +G D TL+ G + L +
Sbjct: 762 ALLLAHGADPTLKNQEGQTPLDLV 785
Score = 102 bits (244), Expect = 5e-21
Identities = 89/267 (33%), Positives = 122/267 (45%), Gaps = 21/267 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 545 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL---WKFTPLHEAAA 601
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL ++ D +++LL A
Sbjct: 602 KGKYEICKLLLQHGADPTKKNRDGNTPLD--LVKDGDTDIQDLLRGDAA----------- 648
Query: 222 LHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G + K L + + R G +T LHLAA + E A LL HGA ++
Sbjct: 649 LLDAAKKGCLARVKKLSSPDNVNCRDTQGR-HSTPLHLAAGYNNLEVAEYLLQHGADVNA 707
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A ++V +L+ A V A D TPLH A +G + LLL
Sbjct: 708 QDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKG--RTQLCALLL 765
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA 367
+ GADP + G TPL + + ++ SA
Sbjct: 766 AHGADPTLKNQEGQTPLDLVSADDVSA 792
Score = 100 bits (239), Expect = 2e-20
Identities = 93/281 (33%), Positives = 124/281 (44%), Gaps = 23/281 (8%)
Query: 114 DDAGR--TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKV 171
D AGR T LH + G ++ V+ LL +GA+ D PLH A S V +
Sbjct: 53 DTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGG---LIPLHNACSFGHAEVVNL 109
Query: 172 LIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGS 230
L+ HGAD NA + + +PLH A + +V LL+ GA P T L +A
Sbjct: 110 LLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAK 169
Query: 231 ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAHIDWPNFRGQTPL 289
A T G K L +A G+ E LL + + R TPL
Sbjct: 170 AVLT--------------GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPL 215
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
HLA +++V++L+ ADV AKD PLH A G ++ LL+ GA NA
Sbjct: 216 HLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY--EVTELLVKHGACVNAM 273
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
D + +TPLH AA LLL YG D TL SA+
Sbjct: 274 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAI 314
Score = 95.9 bits (228), Expect = 5e-19
Identities = 87/261 (33%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + +A G+ ++ LL+ G + DD G LH +C G E V LLL HGA PN
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D+ TPLH AA + VL+ HGA+ +D L A K +L
Sbjct: 120 RDN---WNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGR----TALDLADPSAKAVL 172
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
T + + L A S LL + A+ G K+T LHLAA
Sbjct: 173 -------TGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR-KSTPLHLAAGYNRV 224
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +LLL HGA + + PLH A EV E+LV A V A D TPLH A
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 326 IVRGARACDIARLLLSAGADP 346
+ ++ LLLS GADP
Sbjct: 285 ASK--NRVEVCSLLLSYGADP 303
Score = 92.3 bits (219), Expect = 6e-18
Identities = 85/267 (31%), Positives = 127/267 (47%), Gaps = 26/267 (9%)
Query: 148 SSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLE 206
+S K+TPLH AA + V++L+ HGADV+A D PLH A EV + L++
Sbjct: 206 ASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV-------RAA--MGPGKATALH 257
GAC + ++ TPLH AAS LLL+ GAD ++A + P
Sbjct: 266 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKER 325
Query: 258 LAAE-DGHA--ECAR----LLLDHGAHIDWPNFRG----QTPLHLATLA---QSLEVVEM 303
LA E GH+ + AR + ++ NF+ +T LH A + + ++ E+
Sbjct: 326 LAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICEL 385
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ + A++ K + TPLH A + D+ +++ A NA DN G T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHN--DVVEVVVKHEAKVNALDNLGQTSLHRAAYC 443
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
LLL YG D + + G +AL
Sbjct: 444 GHLQTCRLLLSYGCDPNIISLQGFTAL 470
Score = 86.2 bits (204), Expect = 4e-16
Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 11/257 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E T LH++ + V++++ H A N D+ +T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTS---LHRAAY 442
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
L ++L+++G D N S + L E V++LL+ G + + L
Sbjct: 443 CGHLQTCRLLLSYGCDPNI----ISLQGFTALQMGNENVQQLLQEGISLGNSEA--DRQL 496
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA G K L + + ++T LH AA LL HGA + +
Sbjct: 497 LEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKD 556
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 557 KGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKG--KYEICKLLLQH 614
Query: 343 GADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 615 GADPTKKNRDGNTPLDL 631
Score = 81.8 bits (193), Expect = 8e-15
Identities = 89/285 (31%), Positives = 120/285 (42%), Gaps = 29/285 (10%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L + V+ D T LHL+ + V+LLL HGA + D PLH A S
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD---LVPLHNACS 253
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD--------- 212
++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 254 YGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Query: 213 -----TPQVFTETPLH-----VAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAE 261
TPQ+ + + A T++ + ++ P TALH AA
Sbjct: 314 IDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAA 373
Query: 262 DGHA---ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
+ + LLL GA+I+ TPLH+A+ +VVE++V A V A D G
Sbjct: 374 SPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLG 433
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
+T LH A G RLLLS G DPN G+T L + N
Sbjct: 434 QTSLHRAAYCG--HLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 476
Score = 44.0 bits (99), Expect = 0.002
Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 311 VRAKDADGR--TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
V ++D GR TPLH A G + D+ LL GA+ A D+ G PLH A +
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRK--DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEV 106
Query: 369 VLLLLDYGGDVTLRTNGGVSAL 390
V LLL +G D R N + L
Sbjct: 107 VNLLLRHGADPNARDNWNYTPL 128
>AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein.
Length = 1166
Score = 113 bits (272), Expect = 2e-24
Identities = 93/264 (35%), Positives = 122/264 (46%), Gaps = 27/264 (10%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACP 211
++TPLH AA ++ V+ L+ HGADV+A PLH A EV + L++ GA
Sbjct: 526 QSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVV 585
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ ++ TPLH AA+ G KLLL GAD G T L L +DG + LL
Sbjct: 586 NVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN-TPLDLV-KDGDTDIQDLL 643
Query: 272 LDHGAHIDWPNF----------------------RGQTPLHLATLAQSLEVVEMLVDRCA 309
A +D R TPLHLA +LEV E L+ A
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
DV A+D G PLH A G D+A LL+ A NA D + +TPLH AA +
Sbjct: 704 DVNAQDKGGLIPLHNAASYGH--VDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLC 761
Query: 370 LLLLDYGGDVTLRTNGGVSALSFI 393
LLL +G D TL+ G + L +
Sbjct: 762 ALLLAHGADPTLKNQEGQTPLDLV 785
Score = 102 bits (244), Expect = 5e-21
Identities = 89/267 (33%), Positives = 122/267 (45%), Gaps = 21/267 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 545 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL---WKFTPLHEAAA 601
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL ++ D +++LL A
Sbjct: 602 KGKYEICKLLLQHGADPTKKNRDGNTPLD--LVKDGDTDIQDLLRGDAA----------- 648
Query: 222 LHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G + K L + + R G +T LHLAA + E A LL HGA ++
Sbjct: 649 LLDAAKKGCLARVKKLSSPDNVNCRDTQGR-HSTPLHLAAGYNNLEVAEYLLQHGADVNA 707
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A ++V +L+ A V A D TPLH A +G + LLL
Sbjct: 708 QDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKG--RTQLCALLL 765
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA 367
+ GADP + G TPL + + ++ SA
Sbjct: 766 AHGADPTLKNQEGQTPLDLVSADDVSA 792
Score = 100 bits (239), Expect = 2e-20
Identities = 93/281 (33%), Positives = 124/281 (44%), Gaps = 23/281 (8%)
Query: 114 DDAGR--TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKV 171
D AGR T LH + G ++ V+ LL +GA+ D PLH A S V +
Sbjct: 53 DTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGG---LIPLHNACSFGHAEVVNL 109
Query: 172 LIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGS 230
L+ HGAD NA + + +PLH A + +V LL+ GA P T L +A
Sbjct: 110 LLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAK 169
Query: 231 ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAHIDWPNFRGQTPL 289
A T G K L +A G+ E LL + + R TPL
Sbjct: 170 AVLT--------------GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPL 215
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
HLA +++V++L+ ADV AKD PLH A G ++ LL+ GA NA
Sbjct: 216 HLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY--EVTELLVKHGACVNAM 273
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
D + +TPLH AA LLL YG D TL SA+
Sbjct: 274 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAI 314
Score = 95.9 bits (228), Expect = 5e-19
Identities = 87/261 (33%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + +A G+ ++ LL+ G + DD G LH +C G E V LLL HGA PN
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D+ TPLH AA + VL+ HGA+ +D L A K +L
Sbjct: 120 RDN---WNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGR----TALDLADPSAKAVL 172
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
T + + L A S LL + A+ G K+T LHLAA
Sbjct: 173 -------TGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR-KSTPLHLAAGYNRV 224
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +LLL HGA + + PLH A EV E+LV A V A D TPLH A
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 326 IVRGARACDIARLLLSAGADP 346
+ ++ LLLS GADP
Sbjct: 285 ASK--NRVEVCSLLLSYGADP 303
Score = 92.3 bits (219), Expect = 6e-18
Identities = 85/267 (31%), Positives = 127/267 (47%), Gaps = 26/267 (9%)
Query: 148 SSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLE 206
+S K+TPLH AA + V++L+ HGADV+A D PLH A EV + L++
Sbjct: 206 ASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV-------RAA--MGPGKATALH 257
GAC + ++ TPLH AAS LLL+ GAD ++A + P
Sbjct: 266 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKER 325
Query: 258 LAAE-DGHA--ECAR----LLLDHGAHIDWPNFRG----QTPLHLATLA---QSLEVVEM 303
LA E GH+ + AR + ++ NF+ +T LH A + + ++ E+
Sbjct: 326 LAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICEL 385
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ + A++ K + TPLH A + D+ +++ A NA DN G T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHN--DVVEVVVKHEAKVNALDNLGQTSLHRAAYC 443
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
LLL YG D + + G +AL
Sbjct: 444 GHLQTCRLLLSYGCDPNIISLQGFTAL 470
Score = 86.2 bits (204), Expect = 4e-16
Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 11/257 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E T LH++ + V++++ H A N D+ +T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTS---LHRAAY 442
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
L ++L+++G D N S + L E V++LL+ G + + L
Sbjct: 443 CGHLQTCRLLLSYGCDPNI----ISLQGFTALQMGNENVQQLLQEGISLGNSEA--DRQL 496
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA G K L + + ++T LH AA LL HGA + +
Sbjct: 497 LEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKD 556
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 557 KGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKG--KYEICKLLLQH 614
Query: 343 GADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 615 GADPTKKNRDGNTPLDL 631
Score = 81.8 bits (193), Expect = 8e-15
Identities = 89/285 (31%), Positives = 120/285 (42%), Gaps = 29/285 (10%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L + V+ D T LHL+ + V+LLL HGA + D PLH A S
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD---LVPLHNACS 253
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD--------- 212
++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 254 YGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Query: 213 -----TPQVFTETPLH-----VAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAE 261
TPQ+ + + A T++ + ++ P TALH AA
Sbjct: 314 IDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAA 373
Query: 262 DGHA---ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
+ + LLL GA+I+ TPLH+A+ +VVE++V A V A D G
Sbjct: 374 SPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLG 433
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
+T LH A G RLLLS G DPN G+T L + N
Sbjct: 434 QTSLHRAAYCG--HLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 476
Score = 44.0 bits (99), Expect = 0.002
Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 311 VRAKDADGR--TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
V ++D GR TPLH A G + D+ LL GA+ A D+ G PLH A +
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRK--DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEV 106
Query: 369 VLLLLDYGGDVTLRTNGGVSAL 390
V LLL +G D R N + L
Sbjct: 107 VNLLLRHGADPNARDNWNYTPL 128
>AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 113 bits (272), Expect = 2e-24
Identities = 93/264 (35%), Positives = 122/264 (46%), Gaps = 27/264 (10%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACP 211
++TPLH AA ++ V+ L+ HGADV+A PLH A EV + L++ GA
Sbjct: 526 QSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVV 585
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ ++ TPLH AA+ G KLLL GAD G T L L +DG + LL
Sbjct: 586 NVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN-TPLDLV-KDGDTDIQDLL 643
Query: 272 LDHGAHIDWPNF----------------------RGQTPLHLATLAQSLEVVEMLVDRCA 309
A +D R TPLHLA +LEV E L+ A
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
DV A+D G PLH A G D+A LL+ A NA D + +TPLH AA +
Sbjct: 704 DVNAQDKGGLIPLHNAASYGH--VDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLC 761
Query: 370 LLLLDYGGDVTLRTNGGVSALSFI 393
LLL +G D TL+ G + L +
Sbjct: 762 ALLLAHGADPTLKNQEGQTPLDLV 785
Score = 102 bits (244), Expect = 5e-21
Identities = 89/267 (33%), Positives = 122/267 (45%), Gaps = 21/267 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 545 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL---WKFTPLHEAAA 601
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL ++ D +++LL A
Sbjct: 602 KGKYEICKLLLQHGADPTKKNRDGNTPLD--LVKDGDTDIQDLLRGDAA----------- 648
Query: 222 LHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G + K L + + R G +T LHLAA + E A LL HGA ++
Sbjct: 649 LLDAAKKGCLARVKKLSSPDNVNCRDTQGR-HSTPLHLAAGYNNLEVAEYLLQHGADVNA 707
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A ++V +L+ A V A D TPLH A +G + LLL
Sbjct: 708 QDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKG--RTQLCALLL 765
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA 367
+ GADP + G TPL + + ++ SA
Sbjct: 766 AHGADPTLKNQEGQTPLDLVSADDVSA 792
Score = 100 bits (239), Expect = 2e-20
Identities = 93/281 (33%), Positives = 124/281 (44%), Gaps = 23/281 (8%)
Query: 114 DDAGR--TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKV 171
D AGR T LH + G ++ V+ LL +GA+ D PLH A S V +
Sbjct: 53 DTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGG---LIPLHNACSFGHAEVVNL 109
Query: 172 LIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGS 230
L+ HGAD NA + + +PLH A + +V LL+ GA P T L +A
Sbjct: 110 LLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAK 169
Query: 231 ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAHIDWPNFRGQTPL 289
A T G K L +A G+ E LL + + R TPL
Sbjct: 170 AVLT--------------GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPL 215
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
HLA +++V++L+ ADV AKD PLH A G ++ LL+ GA NA
Sbjct: 216 HLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY--EVTELLVKHGACVNAM 273
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
D + +TPLH AA LLL YG D TL SA+
Sbjct: 274 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAI 314
Score = 95.9 bits (228), Expect = 5e-19
Identities = 87/261 (33%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + +A G+ ++ LL+ G + DD G LH +C G E V LLL HGA PN
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D+ TPLH AA + VL+ HGA+ +D L A K +L
Sbjct: 120 RDN---WNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGR----TALDLADPSAKAVL 172
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
T + + L A S LL + A+ G K+T LHLAA
Sbjct: 173 -------TGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR-KSTPLHLAAGYNRV 224
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +LLL HGA + + PLH A EV E+LV A V A D TPLH A
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 326 IVRGARACDIARLLLSAGADP 346
+ ++ LLLS GADP
Sbjct: 285 ASK--NRVEVCSLLLSYGADP 303
Score = 92.3 bits (219), Expect = 6e-18
Identities = 85/267 (31%), Positives = 127/267 (47%), Gaps = 26/267 (9%)
Query: 148 SSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLE 206
+S K+TPLH AA + V++L+ HGADV+A D PLH A EV + L++
Sbjct: 206 ASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV-------RAA--MGPGKATALH 257
GAC + ++ TPLH AAS LLL+ GAD ++A + P
Sbjct: 266 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKER 325
Query: 258 LAAE-DGHA--ECAR----LLLDHGAHIDWPNFRG----QTPLHLATLA---QSLEVVEM 303
LA E GH+ + AR + ++ NF+ +T LH A + + ++ E+
Sbjct: 326 LAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICEL 385
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ + A++ K + TPLH A + D+ +++ A NA DN G T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHN--DVVEVVVKHEAKVNALDNLGQTSLHRAAYC 443
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
LLL YG D + + G +AL
Sbjct: 444 GHLQTCRLLLSYGCDPNIISLQGFTAL 470
Score = 86.2 bits (204), Expect = 4e-16
Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 11/257 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E T LH++ + V++++ H A N D+ +T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTS---LHRAAY 442
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
L ++L+++G D N S + L E V++LL+ G + + L
Sbjct: 443 CGHLQTCRLLLSYGCDPNI----ISLQGFTALQMGNENVQQLLQEGISLGNSEA--DRQL 496
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA G K L + + ++T LH AA LL HGA + +
Sbjct: 497 LEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKD 556
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 557 KGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKG--KYEICKLLLQH 614
Query: 343 GADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 615 GADPTKKNRDGNTPLDL 631
Score = 81.8 bits (193), Expect = 8e-15
Identities = 89/285 (31%), Positives = 120/285 (42%), Gaps = 29/285 (10%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L + V+ D T LHL+ + V+LLL HGA + D PLH A S
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD---LVPLHNACS 253
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD--------- 212
++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 254 YGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Query: 213 -----TPQVFTETPLH-----VAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAE 261
TPQ+ + + A T++ + ++ P TALH AA
Sbjct: 314 IDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAA 373
Query: 262 DGHA---ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
+ + LLL GA+I+ TPLH+A+ +VVE++V A V A D G
Sbjct: 374 SPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLG 433
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
+T LH A G RLLLS G DPN G+T L + N
Sbjct: 434 QTSLHRAAYCG--HLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 476
Score = 44.0 bits (99), Expect = 0.002
Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 311 VRAKDADGR--TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
V ++D GR TPLH A G + D+ LL GA+ A D+ G PLH A +
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRK--DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEV 106
Query: 369 VLLLLDYGGDVTLRTNGGVSAL 390
V LLL +G D R N + L
Sbjct: 107 VNLLLRHGADPNARDNWNYTPL 128
>AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein.
Length = 1166
Score = 113 bits (272), Expect = 2e-24
Identities = 93/264 (35%), Positives = 122/264 (46%), Gaps = 27/264 (10%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACP 211
++TPLH AA ++ V+ L+ HGADV+A PLH A EV + L++ GA
Sbjct: 526 QSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVV 585
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ ++ TPLH AA+ G KLLL GAD G T L L +DG + LL
Sbjct: 586 NVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN-TPLDLV-KDGDTDIQDLL 643
Query: 272 LDHGAHIDWPNF----------------------RGQTPLHLATLAQSLEVVEMLVDRCA 309
A +D R TPLHLA +LEV E L+ A
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
DV A+D G PLH A G D+A LL+ A NA D + +TPLH AA +
Sbjct: 704 DVNAQDKGGLIPLHNAASYGH--VDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLC 761
Query: 370 LLLLDYGGDVTLRTNGGVSALSFI 393
LLL +G D TL+ G + L +
Sbjct: 762 ALLLAHGADPTLKNQEGQTPLDLV 785
Score = 102 bits (244), Expect = 5e-21
Identities = 89/267 (33%), Positives = 122/267 (45%), Gaps = 21/267 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 545 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL---WKFTPLHEAAA 601
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL ++ D +++LL A
Sbjct: 602 KGKYEICKLLLQHGADPTKKNRDGNTPLD--LVKDGDTDIQDLLRGDAA----------- 648
Query: 222 LHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G + K L + + R G +T LHLAA + E A LL HGA ++
Sbjct: 649 LLDAAKKGCLARVKKLSSPDNVNCRDTQGR-HSTPLHLAAGYNNLEVAEYLLQHGADVNA 707
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A ++V +L+ A V A D TPLH A +G + LLL
Sbjct: 708 QDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKG--RTQLCALLL 765
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA 367
+ GADP + G TPL + + ++ SA
Sbjct: 766 AHGADPTLKNQEGQTPLDLVSADDVSA 792
Score = 100 bits (239), Expect = 2e-20
Identities = 93/281 (33%), Positives = 124/281 (44%), Gaps = 23/281 (8%)
Query: 114 DDAGR--TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKV 171
D AGR T LH + G ++ V+ LL +GA+ D PLH A S V +
Sbjct: 53 DTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGG---LIPLHNACSFGHAEVVNL 109
Query: 172 LIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGS 230
L+ HGAD NA + + +PLH A + +V LL+ GA P T L +A
Sbjct: 110 LLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAK 169
Query: 231 ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAHIDWPNFRGQTPL 289
A T G K L +A G+ E LL + + R TPL
Sbjct: 170 AVLT--------------GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPL 215
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
HLA +++V++L+ ADV AKD PLH A G ++ LL+ GA NA
Sbjct: 216 HLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY--EVTELLVKHGACVNAM 273
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
D + +TPLH AA LLL YG D TL SA+
Sbjct: 274 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAI 314
Score = 95.9 bits (228), Expect = 5e-19
Identities = 87/261 (33%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + +A G+ ++ LL+ G + DD G LH +C G E V LLL HGA PN
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D+ TPLH AA + VL+ HGA+ +D L A K +L
Sbjct: 120 RDN---WNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGR----TALDLADPSAKAVL 172
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
T + + L A S LL + A+ G K+T LHLAA
Sbjct: 173 -------TGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR-KSTPLHLAAGYNRV 224
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +LLL HGA + + PLH A EV E+LV A V A D TPLH A
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 326 IVRGARACDIARLLLSAGADP 346
+ ++ LLLS GADP
Sbjct: 285 ASK--NRVEVCSLLLSYGADP 303
Score = 92.3 bits (219), Expect = 6e-18
Identities = 85/267 (31%), Positives = 127/267 (47%), Gaps = 26/267 (9%)
Query: 148 SSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLE 206
+S K+TPLH AA + V++L+ HGADV+A D PLH A EV + L++
Sbjct: 206 ASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV-------RAA--MGPGKATALH 257
GAC + ++ TPLH AAS LLL+ GAD ++A + P
Sbjct: 266 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKER 325
Query: 258 LAAE-DGHA--ECAR----LLLDHGAHIDWPNFRG----QTPLHLATLA---QSLEVVEM 303
LA E GH+ + AR + ++ NF+ +T LH A + + ++ E+
Sbjct: 326 LAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICEL 385
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ + A++ K + TPLH A + D+ +++ A NA DN G T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHN--DVVEVVVKHEAKVNALDNLGQTSLHRAAYC 443
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
LLL YG D + + G +AL
Sbjct: 444 GHLQTCRLLLSYGCDPNIISLQGFTAL 470
Score = 86.2 bits (204), Expect = 4e-16
Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 11/257 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E T LH++ + V++++ H A N D+ +T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTS---LHRAAY 442
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
L ++L+++G D N S + L E V++LL+ G + + L
Sbjct: 443 CGHLQTCRLLLSYGCDPNI----ISLQGFTALQMGNENVQQLLQEGISLGNSEA--DRQL 496
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA G K L + + ++T LH AA LL HGA + +
Sbjct: 497 LEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKD 556
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 557 KGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKG--KYEICKLLLQH 614
Query: 343 GADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 615 GADPTKKNRDGNTPLDL 631
Score = 81.8 bits (193), Expect = 8e-15
Identities = 89/285 (31%), Positives = 120/285 (42%), Gaps = 29/285 (10%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L + V+ D T LHL+ + V+LLL HGA + D PLH A S
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD---LVPLHNACS 253
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD--------- 212
++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 254 YGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Query: 213 -----TPQVFTETPLH-----VAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAE 261
TPQ+ + + A T++ + ++ P TALH AA
Sbjct: 314 IDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAA 373
Query: 262 DGHA---ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
+ + LLL GA+I+ TPLH+A+ +VVE++V A V A D G
Sbjct: 374 SPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLG 433
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
+T LH A G RLLLS G DPN G+T L + N
Sbjct: 434 QTSLHRAAYCG--HLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 476
Score = 44.0 bits (99), Expect = 0.002
Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 311 VRAKDADGR--TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
V ++D GR TPLH A G + D+ LL GA+ A D+ G PLH A +
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRK--DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEV 106
Query: 369 VLLLLDYGGDVTLRTNGGVSAL 390
V LLL +G D R N + L
Sbjct: 107 VNLLLRHGADPNARDNWNYTPL 128
>AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein.
Length = 1166
Score = 113 bits (272), Expect = 2e-24
Identities = 93/264 (35%), Positives = 122/264 (46%), Gaps = 27/264 (10%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACP 211
++TPLH AA ++ V+ L+ HGADV+A PLH A EV + L++ GA
Sbjct: 526 QSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVV 585
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ ++ TPLH AA+ G KLLL GAD G T L L +DG + LL
Sbjct: 586 NVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN-TPLDLV-KDGDTDIQDLL 643
Query: 272 LDHGAHIDWPNF----------------------RGQTPLHLATLAQSLEVVEMLVDRCA 309
A +D R TPLHLA +LEV E L+ A
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
DV A+D G PLH A G D+A LL+ A NA D + +TPLH AA +
Sbjct: 704 DVNAQDKGGLIPLHNAASYGH--VDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLC 761
Query: 370 LLLLDYGGDVTLRTNGGVSALSFI 393
LLL +G D TL+ G + L +
Sbjct: 762 ALLLAHGADPTLKNQEGQTPLDLV 785
Score = 102 bits (244), Expect = 5e-21
Identities = 89/267 (33%), Positives = 122/267 (45%), Gaps = 21/267 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 545 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL---WKFTPLHEAAA 601
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL ++ D +++LL A
Sbjct: 602 KGKYEICKLLLQHGADPTKKNRDGNTPLD--LVKDGDTDIQDLLRGDAA----------- 648
Query: 222 LHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G + K L + + R G +T LHLAA + E A LL HGA ++
Sbjct: 649 LLDAAKKGCLARVKKLSSPDNVNCRDTQGR-HSTPLHLAAGYNNLEVAEYLLQHGADVNA 707
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A ++V +L+ A V A D TPLH A +G + LLL
Sbjct: 708 QDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKG--RTQLCALLL 765
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA 367
+ GADP + G TPL + + ++ SA
Sbjct: 766 AHGADPTLKNQEGQTPLDLVSADDVSA 792
Score = 100 bits (239), Expect = 2e-20
Identities = 93/281 (33%), Positives = 124/281 (44%), Gaps = 23/281 (8%)
Query: 114 DDAGR--TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKV 171
D AGR T LH + G ++ V+ LL +GA+ D PLH A S V +
Sbjct: 53 DTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGG---LIPLHNACSFGHAEVVNL 109
Query: 172 LIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGS 230
L+ HGAD NA + + +PLH A + +V LL+ GA P T L +A
Sbjct: 110 LLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAK 169
Query: 231 ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAHIDWPNFRGQTPL 289
A T G K L +A G+ E LL + + R TPL
Sbjct: 170 AVLT--------------GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPL 215
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
HLA +++V++L+ ADV AKD PLH A G ++ LL+ GA NA
Sbjct: 216 HLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY--EVTELLVKHGACVNAM 273
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
D + +TPLH AA LLL YG D TL SA+
Sbjct: 274 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAI 314
Score = 95.9 bits (228), Expect = 5e-19
Identities = 87/261 (33%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + +A G+ ++ LL+ G + DD G LH +C G E V LLL HGA PN
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D+ TPLH AA + VL+ HGA+ +D L A K +L
Sbjct: 120 RDN---WNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGR----TALDLADPSAKAVL 172
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
T + + L A S LL + A+ G K+T LHLAA
Sbjct: 173 -------TGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR-KSTPLHLAAGYNRV 224
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +LLL HGA + + PLH A EV E+LV A V A D TPLH A
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 326 IVRGARACDIARLLLSAGADP 346
+ ++ LLLS GADP
Sbjct: 285 ASK--NRVEVCSLLLSYGADP 303
Score = 92.3 bits (219), Expect = 6e-18
Identities = 85/267 (31%), Positives = 127/267 (47%), Gaps = 26/267 (9%)
Query: 148 SSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLE 206
+S K+TPLH AA + V++L+ HGADV+A D PLH A EV + L++
Sbjct: 206 ASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV-------RAA--MGPGKATALH 257
GAC + ++ TPLH AAS LLL+ GAD ++A + P
Sbjct: 266 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKER 325
Query: 258 LAAE-DGHA--ECAR----LLLDHGAHIDWPNFRG----QTPLHLATLA---QSLEVVEM 303
LA E GH+ + AR + ++ NF+ +T LH A + + ++ E+
Sbjct: 326 LAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICEL 385
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ + A++ K + TPLH A + D+ +++ A NA DN G T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHN--DVVEVVVKHEAKVNALDNLGQTSLHRAAYC 443
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
LLL YG D + + G +AL
Sbjct: 444 GHLQTCRLLLSYGCDPNIISLQGFTAL 470
Score = 86.2 bits (204), Expect = 4e-16
Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 11/257 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E T LH++ + V++++ H A N D+ +T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTS---LHRAAY 442
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
L ++L+++G D N S + L E V++LL+ G + + L
Sbjct: 443 CGHLQTCRLLLSYGCDPNI----ISLQGFTALQMGNENVQQLLQEGISLGNSEA--DRQL 496
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA G K L + + ++T LH AA LL HGA + +
Sbjct: 497 LEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKD 556
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 557 KGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKG--KYEICKLLLQH 614
Query: 343 GADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 615 GADPTKKNRDGNTPLDL 631
Score = 81.8 bits (193), Expect = 8e-15
Identities = 89/285 (31%), Positives = 120/285 (42%), Gaps = 29/285 (10%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L + V+ D T LHL+ + V+LLL HGA + D PLH A S
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD---LVPLHNACS 253
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD--------- 212
++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 254 YGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Query: 213 -----TPQVFTETPLH-----VAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAE 261
TPQ+ + + A T++ + ++ P TALH AA
Sbjct: 314 IDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAA 373
Query: 262 DGHA---ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
+ + LLL GA+I+ TPLH+A+ +VVE++V A V A D G
Sbjct: 374 SPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLG 433
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
+T LH A G RLLLS G DPN G+T L + N
Sbjct: 434 QTSLHRAAYCG--HLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 476
Score = 44.0 bits (99), Expect = 0.002
Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 311 VRAKDADGR--TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
V ++D GR TPLH A G + D+ LL GA+ A D+ G PLH A +
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRK--DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEV 106
Query: 369 VLLLLDYGGDVTLRTNGGVSAL 390
V LLL +G D R N + L
Sbjct: 107 VNLLLRHGADPNARDNWNYTPL 128
>AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related protein
protein.
Length = 1265
Score = 113 bits (272), Expect = 2e-24
Identities = 93/264 (35%), Positives = 122/264 (46%), Gaps = 27/264 (10%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACP 211
++TPLH AA ++ V+ L+ HGADV+A PLH A EV + L++ GA
Sbjct: 625 QSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVV 684
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ ++ TPLH AA+ G KLLL GAD G T L L +DG + LL
Sbjct: 685 NVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN-TPLDLV-KDGDTDIQDLL 742
Query: 272 LDHGAHIDWPNF----------------------RGQTPLHLATLAQSLEVVEMLVDRCA 309
A +D R TPLHLA +LEV E L+ A
Sbjct: 743 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 802
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
DV A+D G PLH A G D+A LL+ A NA D + +TPLH AA +
Sbjct: 803 DVNAQDKGGLIPLHNAASYGH--VDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLC 860
Query: 370 LLLLDYGGDVTLRTNGGVSALSFI 393
LLL +G D TL+ G + L +
Sbjct: 861 ALLLAHGADPTLKNQEGQTPLDLV 884
Score = 102 bits (244), Expect = 5e-21
Identities = 89/267 (33%), Positives = 122/267 (45%), Gaps = 21/267 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 644 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL---WKFTPLHEAAA 700
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL ++ D +++LL A
Sbjct: 701 KGKYEICKLLLQHGADPTKKNRDGNTPLD--LVKDGDTDIQDLLRGDAA----------- 747
Query: 222 LHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G + K L + + R G +T LHLAA + E A LL HGA ++
Sbjct: 748 LLDAAKKGCLARVKKLSSPDNVNCRDTQGR-HSTPLHLAAGYNNLEVAEYLLQHGADVNA 806
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A ++V +L+ A V A D TPLH A +G + LLL
Sbjct: 807 QDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKG--RTQLCALLL 864
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA 367
+ GADP + G TPL + + ++ SA
Sbjct: 865 AHGADPTLKNQEGQTPLDLVSADDVSA 891
Score = 101 bits (242), Expect = 9e-21
Identities = 93/281 (33%), Positives = 124/281 (44%), Gaps = 23/281 (8%)
Query: 114 DDAGR--TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKV 171
D AGR T LH + G ++ V+ LL +GA+ D PLH A S V +
Sbjct: 153 DTAGRKSTPLHFAAXFGRKDVVEYLLQNGANVQARDDGG---LIPLHNACSFGHAEVVNL 209
Query: 172 LIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGS 230
L+ HGAD NA + + +PLH A + +V LL+ GA P T L +A
Sbjct: 210 LLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAK 269
Query: 231 ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAHIDWPNFRGQTPL 289
A T G K L +A G+ E LL + + R TPL
Sbjct: 270 AVLT--------------GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPL 315
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
HLA +++V++L+ ADV AKD PLH A G ++ LL+ GA NA
Sbjct: 316 HLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY--EVTELLVKHGACVNAM 373
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
D + +TPLH AA LLL YG D TL SA+
Sbjct: 374 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAI 414
Score = 95.9 bits (228), Expect = 5e-19
Identities = 87/261 (33%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + +A G+ ++ LL+ G + DD G LH +C G E V LLL HGA PN
Sbjct: 160 TPLHFAAXFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 219
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D+ TPLH AA + VL+ HGA+ +D L A K +L
Sbjct: 220 RDN---WNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGR----TALDLADPSAKAVL 272
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
T + + L A S LL + A+ G K+T LHLAA
Sbjct: 273 -------TGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR-KSTPLHLAAGYNRV 324
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +LLL HGA + + PLH A EV E+LV A V A D TPLH A
Sbjct: 325 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 384
Query: 326 IVRGARACDIARLLLSAGADP 346
+ ++ LLLS GADP
Sbjct: 385 ASK--NRVEVCSLLLSYGADP 403
Score = 90.2 bits (214), Expect = 2e-17
Identities = 93/285 (32%), Positives = 123/285 (43%), Gaps = 30/285 (10%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L + V+ D T LHL+ + V+LLL HGA + D PLH A S
Sbjct: 297 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD---LVPLHNACS 353
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD--------- 212
++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 354 YGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 413
Query: 213 -----TPQVFT------ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
TPQ+ + PL VAA A T++ + ++ TALH AA
Sbjct: 414 IDLAPTPQLKERLAYEFQRPL-VAAXAREADVTRIKKHLSLEMVIQASQTHETALHCAAA 472
Query: 262 DGHA---ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
+ + LLL GA+I+ TPLH+A+ +VVE++V A V A D G
Sbjct: 473 SPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLG 532
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
+T LH A G RLLLS G DPN G+T L + N
Sbjct: 533 QTSLHRAAYCG--HLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 575
Score = 88.6 bits (210), Expect = 7e-17
Identities = 86/277 (31%), Positives = 125/277 (45%), Gaps = 36/277 (12%)
Query: 149 STETKATPLHCAASA---KSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKEL 204
+++T T LHCAA++ K ++L+ GA++N + +PLH A +VV+ +
Sbjct: 459 ASQTHETALHCAAASPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVV 518
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED-- 262
++ A + +T LH AA G +LLL+ G D G TAL + E+
Sbjct: 519 VKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQG-FTALQMGNENVQ 577
Query: 263 ---------GHAECARLLLDHGAHIDWPNF----------------RGQTPLHLATLAQS 297
G++E R LL+ D R TPLH A
Sbjct: 578 QLLQEGISLGNSEADRQLLEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNR 637
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+ VVE L+ ADV AKD G PLH A G ++A LL+ GA N AD + +TPL
Sbjct: 638 VSVVEYLLQHGADVHAKDKGGLVPLHNACSYG--HYEVAELLVKHGAVVNVADLWKFTPL 695
Query: 358 H-IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFI 393
H AA ++ C LLL +G D T + G + L +
Sbjct: 696 HEAAAKGKYEIC-KLLLQHGADPTKKNRDGNTPLDLV 731
Score = 86.2 bits (204), Expect = 4e-16
Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 11/257 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E T LH++ + V++++ H A N D+ +T LH AA
Sbjct: 485 LLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTS---LHRAAY 541
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
L ++L+++G D N S + L E V++LL+ G + + L
Sbjct: 542 CGHLQTCRLLLSYGCDPNI----ISLQGFTALQMGNENVQQLLQEGISLGNSEA--DRQL 595
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA G K L + + ++T LH AA LL HGA + +
Sbjct: 596 LEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKD 655
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 656 KGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKG--KYEICKLLLQH 713
Query: 343 GADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 714 GADPTKKNRDGNTPLDL 730
>AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein
protein.
Length = 1166
Score = 113 bits (272), Expect = 2e-24
Identities = 93/264 (35%), Positives = 122/264 (46%), Gaps = 27/264 (10%)
Query: 153 KATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACP 211
++TPLH AA ++ V+ L+ HGADV+A PLH A EV + L++ GA
Sbjct: 526 QSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVV 585
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
+ ++ TPLH AA+ G KLLL GAD G T L L +DG + LL
Sbjct: 586 NVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGN-TPLDLV-KDGDTDIQDLL 643
Query: 272 LDHGAHIDWPNF----------------------RGQTPLHLATLAQSLEVVEMLVDRCA 309
A +D R TPLHLA +LEV E L+ A
Sbjct: 644 RGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGA 703
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
DV A+D G PLH A G D+A LL+ A NA D + +TPLH AA +
Sbjct: 704 DVNAQDKGGLIPLHNAASYGH--VDVAALLIKYNACVNATDKWAFTPLHEAAQKGRTQLC 761
Query: 370 LLLLDYGGDVTLRTNGGVSALSFI 393
LLL +G D TL+ G + L +
Sbjct: 762 ALLLAHGADPTLKNQEGQTPLDLV 785
Score = 102 bits (244), Expect = 5e-21
Identities = 89/267 (33%), Positives = 122/267 (45%), Gaps = 21/267 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 545 LLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADL---WKFTPLHEAAA 601
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL ++ D +++LL A
Sbjct: 602 KGKYEICKLLLQHGADPTKKNRDGNTPLD--LVKDGDTDIQDLLRGDAA----------- 648
Query: 222 LHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G + K L + + R G +T LHLAA + E A LL HGA ++
Sbjct: 649 LLDAAKKGCLARVKKLSSPDNVNCRDTQGR-HSTPLHLAAGYNNLEVAEYLLQHGADVNA 707
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A ++V +L+ A V A D TPLH A +G + LLL
Sbjct: 708 QDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKG--RTQLCALLL 765
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSA 367
+ GADP + G TPL + + ++ SA
Sbjct: 766 AHGADPTLKNQEGQTPLDLVSADDVSA 792
Score = 100 bits (239), Expect = 2e-20
Identities = 93/281 (33%), Positives = 124/281 (44%), Gaps = 23/281 (8%)
Query: 114 DDAGR--TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKV 171
D AGR T LH + G ++ V+ LL +GA+ D PLH A S V +
Sbjct: 53 DTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGG---LIPLHNACSFGHAEVVNL 109
Query: 172 LIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGS 230
L+ HGAD NA + + +PLH A + +V LL+ GA P T L +A
Sbjct: 110 LLRHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLADPSAK 169
Query: 231 ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAHIDWPNFRGQTPL 289
A T G K L +A G+ E LL + + R TPL
Sbjct: 170 AVLT--------------GEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPL 215
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
HLA +++V++L+ ADV AKD PLH A G ++ LL+ GA NA
Sbjct: 216 HLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHY--EVTELLVKHGACVNAM 273
Query: 350 DNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
D + +TPLH AA LLL YG D TL SA+
Sbjct: 274 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAI 314
Score = 95.9 bits (228), Expect = 5e-19
Identities = 87/261 (33%), Positives = 114/261 (43%), Gaps = 17/261 (6%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + +A G+ ++ LL+ G + DD G LH +C G E V LLL HGA PN
Sbjct: 60 TPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNA 119
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D+ TPLH AA + VL+ HGA+ +D L A K +L
Sbjct: 120 RDN---WNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGR----TALDLADPSAKAVL 172
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
T + + L A S LL + A+ G K+T LHLAA
Sbjct: 173 -------TGEYKKDELLESARSGNEEKMMALLTPLNVNCHASDGR-KSTPLHLAAGYNRV 224
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +LLL HGA + + PLH A EV E+LV A V A D TPLH A
Sbjct: 225 KIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEA 284
Query: 326 IVRGARACDIARLLLSAGADP 346
+ ++ LLLS GADP
Sbjct: 285 ASK--NRVEVCSLLLSYGADP 303
Score = 92.3 bits (219), Expect = 6e-18
Identities = 85/267 (31%), Positives = 127/267 (47%), Gaps = 26/267 (9%)
Query: 148 SSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLE 206
+S K+TPLH AA + V++L+ HGADV+A D PLH A EV + L++
Sbjct: 206 ASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVK 265
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV-------RAA--MGPGKATALH 257
GAC + ++ TPLH AAS LLL+ GAD ++A + P
Sbjct: 266 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKER 325
Query: 258 LAAE-DGHA--ECAR----LLLDHGAHIDWPNFRG----QTPLHLATLA---QSLEVVEM 303
LA E GH+ + AR + ++ NF+ +T LH A + + ++ E+
Sbjct: 326 LAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICEL 385
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ + A++ K + TPLH A + D+ +++ A NA DN G T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHN--DVVEVVVKHEAKVNALDNLGQTSLHRAAYC 443
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
LLL YG D + + G +AL
Sbjct: 444 GHLQTCRLLLSYGCDPNIISLQGFTAL 470
Score = 86.2 bits (204), Expect = 4e-16
Identities = 76/257 (29%), Positives = 111/257 (43%), Gaps = 11/257 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E T LH++ + V++++ H A N D+ +T LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTS---LHRAAY 442
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
L ++L+++G D N S + L E V++LL+ G + + L
Sbjct: 443 CGHLQTCRLLLSYGCDPNI----ISLQGFTALQMGNENVQQLLQEGISLGNSEA--DRQL 496
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA G K L + + ++T LH AA LL HGA + +
Sbjct: 497 LEAAKAGDVETVKKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKD 556
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 557 KGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKG--KYEICKLLLQH 614
Query: 343 GADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 615 GADPTKKNRDGNTPLDL 631
Score = 81.8 bits (193), Expect = 8e-15
Identities = 89/285 (31%), Positives = 120/285 (42%), Gaps = 29/285 (10%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L + V+ D T LHL+ + V+LLL HGA + D PLH A S
Sbjct: 197 LTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGD---LVPLHNACS 253
Query: 163 AKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD--------- 212
++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 254 YGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSA 313
Query: 213 -----TPQVFTETPLH-----VAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAE 261
TPQ+ + + A T++ + ++ P TALH AA
Sbjct: 314 IDLAPTPQLKERLAYEFKGHSLLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAA 373
Query: 262 DGHA---ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
+ + LLL GA+I+ TPLH+A+ +VVE++V A V A D G
Sbjct: 374 SPYPKRKQICELLLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLG 433
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
+T LH A G RLLLS G DPN G+T L + N
Sbjct: 434 QTSLHRAAYCG--HLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 476
Score = 44.0 bits (99), Expect = 0.002
Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 311 VRAKDADGR--TPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
V ++D GR TPLH A G + D+ LL GA+ A D+ G PLH A +
Sbjct: 49 VNSRDTAGRKSTPLHFAAGFGRK--DVVEYLLQNGANVQARDDGGLIPLHNACSFGHAEV 106
Query: 369 VLLLLDYGGDVTLRTNGGVSAL 390
V LLL +G D R N + L
Sbjct: 107 VNLLLRHGADPNARDNWNYTPL 128
>BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein.
Length = 716
Score = 113 bits (271), Expect = 3e-24
Identities = 81/238 (34%), Positives = 122/238 (51%), Gaps = 7/238 (2%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNAGL---SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
L+ +A L V +++ G D N + + RSPLH A + ++ L++AGA DT
Sbjct: 160 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 219
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPL AA K L+ AGA V G +T LHLAA+ GH E + LL
Sbjct: 220 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEG-STCLHLAAKKGHYEVVQYLLS 278
Query: 274 HGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+G ++ + G TP+ AT + +++V++L+ + +D+ +D + LH A G
Sbjct: 279 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGC-- 336
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
DIA +LL+A D +A + G +PLHIAA CV+L L DVTL+ G + L
Sbjct: 337 VDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 394
Score = 98.7 bits (235), Expect = 7e-20
Identities = 75/244 (30%), Positives = 114/244 (46%), Gaps = 4/244 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+ S G + V L+L G PN + + K +PLH AA A + +L+ GA+++
Sbjct: 160 LYFSARQGELQKVLLMLVDGIDPN-FKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANID 218
Query: 181 AGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
D R+PL A ++ E VK L++AGA D T LH+AA G + LL+
Sbjct: 219 TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 278
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G G T + A E H + +LLL G+ I+ + LH A + ++
Sbjct: 279 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVD 338
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
+ E+L+ D+ A + G +PLH A C + L LS +D + G TPL
Sbjct: 339 IAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVV--LFLSRDSDVTLKNKEGETPLQC 396
Query: 360 AALN 363
A+LN
Sbjct: 397 ASLN 400
Score = 66.5 bits (155), Expect = 3e-10
Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 3/143 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G D D G TCLHL+ G E V+ LL +G + + TP+ A
Sbjct: 243 LIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG--QMDVNCQDDGGWTPMIWATE 300
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + VK+L++ G+D+N ++ + LH+A S ++ + LL A + ++P
Sbjct: 301 YKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSP 360
Query: 222 LHVAASLGSASCTKLLLNAGADV 244
LH+AA C L L+ +DV
Sbjct: 361 LHIAARENRYDCVVLFLSRDSDV 383
Score = 39.5 bits (88), Expect = 0.043
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E + L+ NG D Q +GG+ T ++WA L+ LL G D + D+
Sbjct: 271 EVVQYLLSNGQMDVNCQ----DDGGW---TPMIWATEYKHVDLVKLLLSKGSDINIRDNE 323
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + G + ++LL + + + +PLH AA CV + ++
Sbjct: 324 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGD---SPLHIAARENRYDCVVLFLSRD 380
Query: 177 ADVN-AGLSDRSPLHYAVLSDAPEVVKELLEA--GACPDTP 214
+DV +PL A L+ ++ +A + PD P
Sbjct: 381 SDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRP 421
Score = 35.9 bits (79), Expect = 0.52
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ MLVD + + + + R+PLH A G DI +L+ AGA+ + TPL
Sbjct: 171 KVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGH--VDICHMLVQAGANIDTCSEDQRTPL 228
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA N V L+ G V + G + L ++ + +YL
Sbjct: 229 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 276
>AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone
methyltransferase 1 protein.
Length = 1267
Score = 113 bits (271), Expect = 3e-24
Identities = 81/238 (34%), Positives = 122/238 (51%), Gaps = 7/238 (2%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNAGL---SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
L+ +A L V +++ G D N + + RSPLH A + ++ L++AGA DT
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPL AA K L+ AGA V G +T LHLAA+ GH E + LL
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEG-STCLHLAAKKGHYEVVQYLLS 829
Query: 274 HGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+G ++ + G TP+ AT + +++V++L+ + +D+ +D + LH A G
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGC-- 887
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
DIA +LL+A D +A + G +PLHIAA CV+L L DVTL+ G + L
Sbjct: 888 VDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 945
Score = 98.7 bits (235), Expect = 7e-20
Identities = 75/244 (30%), Positives = 114/244 (46%), Gaps = 4/244 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+ S G + V L+L G PN + + K +PLH AA A + +L+ GA+++
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPN-FKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANID 769
Query: 181 AGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
D R+PL A ++ E VK L++AGA D T LH+AA G + LL+
Sbjct: 770 TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 829
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G G T + A E H + +LLL G+ I+ + LH A + ++
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVD 889
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
+ E+L+ D+ A + G +PLH A C + L LS +D + G TPL
Sbjct: 890 IAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVV--LFLSRDSDVTLKNKEGETPLQC 947
Query: 360 AALN 363
A+LN
Sbjct: 948 ASLN 951
Score = 66.5 bits (155), Expect = 3e-10
Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 3/143 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G D D G TCLHL+ G E V+ LL +G + + TP+ A
Sbjct: 794 LIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG--QMDVNCQDDGGWTPMIWATE 851
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + VK+L++ G+D+N ++ + LH+A S ++ + LL A + ++P
Sbjct: 852 YKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSP 911
Query: 222 LHVAASLGSASCTKLLLNAGADV 244
LH+AA C L L+ +DV
Sbjct: 912 LHIAARENRYDCVVLFLSRDSDV 934
Score = 39.5 bits (88), Expect = 0.043
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E + L+ NG D Q +GG+ T ++WA L+ LL G D + D+
Sbjct: 822 EVVQYLLSNGQMDVNCQ----DDGGW---TPMIWATEYKHVDLVKLLLSKGSDINIRDNE 874
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + G + ++LL + + + +PLH AA CV + ++
Sbjct: 875 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGD---SPLHIAARENRYDCVVLFLSRD 931
Query: 177 ADVN-AGLSDRSPLHYAVLSDAPEVVKELLEA--GACPDTP 214
+DV +PL A L+ ++ +A + PD P
Sbjct: 932 SDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRP 972
Score = 35.9 bits (79), Expect = 0.52
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ MLVD + + + + R+PLH A G DI +L+ AGA+ + TPL
Sbjct: 722 KVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGH--VDICHMLVQAGANIDTCSEDQRTPL 779
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA N V L+ G V + G + L ++ + +YL
Sbjct: 780 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 827
>AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 113 bits (271), Expect = 3e-24
Identities = 81/238 (34%), Positives = 122/238 (51%), Gaps = 7/238 (2%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNAGL---SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
L+ +A L V +++ G D N + + RSPLH A + ++ L++AGA DT
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPL AA K L+ AGA V G +T LHLAA+ GH E + LL
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEG-STCLHLAAKKGHYEVVQYLLS 829
Query: 274 HGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+G ++ + G TP+ AT + +++V++L+ + +D+ +D + LH A G
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGC-- 887
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
DIA +LL+A D +A + G +PLHIAA CV+L L DVTL+ G + L
Sbjct: 888 VDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 945
Score = 98.7 bits (235), Expect = 7e-20
Identities = 75/244 (30%), Positives = 114/244 (46%), Gaps = 4/244 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+ S G + V L+L G PN + + K +PLH AA A + +L+ GA+++
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPN-FKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANID 769
Query: 181 AGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
D R+PL A ++ E VK L++AGA D T LH+AA G + LL+
Sbjct: 770 TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 829
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G G T + A E H + +LLL G+ I+ + LH A + ++
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVD 889
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
+ E+L+ D+ A + G +PLH A C + L LS +D + G TPL
Sbjct: 890 IAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVV--LFLSRDSDVTLKNKEGETPLQC 947
Query: 360 AALN 363
A+LN
Sbjct: 948 ASLN 951
Score = 66.5 bits (155), Expect = 3e-10
Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 3/143 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G D D G TCLHL+ G E V+ LL +G + + TP+ A
Sbjct: 794 LIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG--QMDVNCQDDGGWTPMIWATE 851
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + VK+L++ G+D+N ++ + LH+A S ++ + LL A + ++P
Sbjct: 852 YKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSP 911
Query: 222 LHVAASLGSASCTKLLLNAGADV 244
LH+AA C L L+ +DV
Sbjct: 912 LHIAARENRYDCVVLFLSRDSDV 934
Score = 39.5 bits (88), Expect = 0.043
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E + L+ NG D Q +GG+ T ++WA L+ LL G D + D+
Sbjct: 822 EVVQYLLSNGQMDVNCQ----DDGGW---TPMIWATEYKHVDLVKLLLSKGSDINIRDNE 874
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + G + ++LL + + + +PLH AA CV + ++
Sbjct: 875 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGD---SPLHIAARENRYDCVVLFLSRD 931
Query: 177 ADVN-AGLSDRSPLHYAVLSDAPEVVKELLEA--GACPDTP 214
+DV +PL A L+ ++ +A + PD P
Sbjct: 932 SDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRP 972
Score = 35.9 bits (79), Expect = 0.52
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ MLVD + + + + R+PLH A G DI +L+ AGA+ + TPL
Sbjct: 722 KVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGH--VDICHMLVQAGANIDTCSEDQRTPL 779
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA N V L+ G V + G + L ++ + +YL
Sbjct: 780 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 827
>AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 113 bits (271), Expect = 3e-24
Identities = 81/238 (34%), Positives = 122/238 (51%), Gaps = 7/238 (2%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNAGL---SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
L+ +A L V +++ G D N + + RSPLH A + ++ L++AGA DT
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 770
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPL AA K L+ AGA V G +T LHLAA+ GH E + LL
Sbjct: 771 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEG-STCLHLAAKKGHYEVVQYLLS 829
Query: 274 HGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+G ++ + G TP+ AT + +++V++L+ + +D+ +D + LH A G
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGC-- 887
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
DIA +LL+A D +A + G +PLHIAA CV+L L DVTL+ G + L
Sbjct: 888 VDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 945
Score = 98.7 bits (235), Expect = 7e-20
Identities = 75/244 (30%), Positives = 114/244 (46%), Gaps = 4/244 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+ S G + V L+L G PN + + K +PLH AA A + +L+ GA+++
Sbjct: 711 LYFSARQGELQKVLLMLVDGIDPN-FKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANID 769
Query: 181 AGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
D R+PL A ++ E VK L++AGA D T LH+AA G + LL+
Sbjct: 770 TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 829
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G G T + A E H + +LLL G+ I+ + LH A + ++
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVD 889
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
+ E+L+ D+ A + G +PLH A C + L LS +D + G TPL
Sbjct: 890 IAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVV--LFLSRDSDVTLKNKEGETPLQC 947
Query: 360 AALN 363
A+LN
Sbjct: 948 ASLN 951
Score = 66.5 bits (155), Expect = 3e-10
Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 3/143 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G D D G TCLHL+ G E V+ LL +G + + TP+ A
Sbjct: 794 LIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG--QMDVNCQDDGGWTPMIWATE 851
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + VK+L++ G+D+N ++ + LH+A S ++ + LL A + ++P
Sbjct: 852 YKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSP 911
Query: 222 LHVAASLGSASCTKLLLNAGADV 244
LH+AA C L L+ +DV
Sbjct: 912 LHIAARENRYDCVVLFLSRDSDV 934
Score = 39.5 bits (88), Expect = 0.043
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E + L+ NG D Q +GG+ T ++WA L+ LL G D + D+
Sbjct: 822 EVVQYLLSNGQMDVNCQ----DDGGW---TPMIWATEYKHVDLVKLLLSKGSDINIRDNE 874
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + G + ++LL + + + +PLH AA CV + ++
Sbjct: 875 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGD---SPLHIAARENRYDCVVLFLSRD 931
Query: 177 ADVN-AGLSDRSPLHYAVLSDAPEVVKELLEA--GACPDTP 214
+DV +PL A L+ ++ +A + PD P
Sbjct: 932 SDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRP 972
Score = 35.9 bits (79), Expect = 0.52
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ MLVD + + + + R+PLH A G DI +L+ AGA+ + TPL
Sbjct: 722 KVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGH--VDICHMLVQAGANIDTCSEDQRTPL 779
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA N V L+ G V + G + L ++ + +YL
Sbjct: 780 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 827
>AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein.
Length = 803
Score = 113 bits (271), Expect = 3e-24
Identities = 81/238 (34%), Positives = 122/238 (51%), Gaps = 7/238 (2%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNAGL---SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
L+ +A L V +++ G D N + + RSPLH A + ++ L++AGA DT
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 420
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPL AA K L+ AGA V G +T LHLAA+ GH E + LL
Sbjct: 421 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEG-STCLHLAAKKGHYEVVQYLLS 479
Query: 274 HGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+G ++ + G TP+ AT + +++V++L+ + +D+ +D + LH A G
Sbjct: 480 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGC-- 537
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
DIA +LL+A D +A + G +PLHIAA CV+L L DVTL+ G + L
Sbjct: 538 VDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 595
Score = 98.7 bits (235), Expect = 7e-20
Identities = 75/244 (30%), Positives = 114/244 (46%), Gaps = 4/244 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+ S G + V L+L G PN + + K +PLH AA A + +L+ GA+++
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPN-FKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANID 419
Query: 181 AGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
D R+PL A ++ E VK L++AGA D T LH+AA G + LL+
Sbjct: 420 TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 479
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G G T + A E H + +LLL G+ I+ + LH A + ++
Sbjct: 480 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVD 539
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
+ E+L+ D+ A + G +PLH A C + L LS +D + G TPL
Sbjct: 540 IAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVV--LFLSRDSDVTLKNKEGETPLQC 597
Query: 360 AALN 363
A+LN
Sbjct: 598 ASLN 601
Score = 66.5 bits (155), Expect = 3e-10
Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 3/143 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G D D G TCLHL+ G E V+ LL +G + + TP+ A
Sbjct: 444 LIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG--QMDVNCQDDGGWTPMIWATE 501
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + VK+L++ G+D+N ++ + LH+A S ++ + LL A + ++P
Sbjct: 502 YKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSP 561
Query: 222 LHVAASLGSASCTKLLLNAGADV 244
LH+AA C L L+ +DV
Sbjct: 562 LHIAARENRYDCVVLFLSRDSDV 584
Score = 39.5 bits (88), Expect = 0.043
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E + L+ NG D Q +GG+ T ++WA L+ LL G D + D+
Sbjct: 472 EVVQYLLSNGQMDVNCQ----DDGGW---TPMIWATEYKHVDLVKLLLSKGSDINIRDNE 524
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + G + ++LL + + + +PLH AA CV + ++
Sbjct: 525 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGD---SPLHIAARENRYDCVVLFLSRD 581
Query: 177 ADVN-AGLSDRSPLHYAVLSDAPEVVKELLEA--GACPDTP 214
+DV +PL A L+ ++ +A + PD P
Sbjct: 582 SDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRP 622
Score = 35.9 bits (79), Expect = 0.52
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ MLVD + + + + R+PLH A G DI +L+ AGA+ + TPL
Sbjct: 372 KVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGH--VDICHMLVQAGANIDTCSEDQRTPL 429
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA N V L+ G V + G + L ++ + +YL
Sbjct: 430 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 477
>AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein.
Length = 917
Score = 113 bits (271), Expect = 3e-24
Identities = 81/238 (34%), Positives = 122/238 (51%), Gaps = 7/238 (2%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNAGL---SDRSPLHYAVLSDAPEVVKELLEAGACPDT 213
L+ +A L V +++ G D N + + RSPLH A + ++ L++AGA DT
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANIDT 420
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPL AA K L+ AGA V G +T LHLAA+ GH E + LL
Sbjct: 421 CSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEG-STCLHLAAKKGHYEVVQYLLS 479
Query: 274 HGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+G ++ + G TP+ AT + +++V++L+ + +D+ +D + LH A G
Sbjct: 480 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGC-- 537
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
DIA +LL+A D +A + G +PLHIAA CV+L L DVTL+ G + L
Sbjct: 538 VDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPL 595
Score = 98.7 bits (235), Expect = 7e-20
Identities = 75/244 (30%), Positives = 114/244 (46%), Gaps = 4/244 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+ S G + V L+L G PN + + K +PLH AA A + +L+ GA+++
Sbjct: 361 LYFSARQGELQKVLLMLVDGIDPN-FKMEHQNKRSPLHAAAEAGHVDICHMLVQAGANID 419
Query: 181 AGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
D R+PL A ++ E VK L++AGA D T LH+AA G + LL+
Sbjct: 420 TCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 479
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G G T + A E H + +LLL G+ I+ + LH A + ++
Sbjct: 480 NGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVD 539
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
+ E+L+ D+ A + G +PLH A C + L LS +D + G TPL
Sbjct: 540 IAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVV--LFLSRDSDVTLKNKEGETPLQC 597
Query: 360 AALN 363
A+LN
Sbjct: 598 ASLN 601
Score = 66.5 bits (155), Expect = 3e-10
Identities = 44/143 (30%), Positives = 70/143 (48%), Gaps = 3/143 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+K G D D G TCLHL+ G E V+ LL +G + + TP+ A
Sbjct: 444 LIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLSNG--QMDVNCQDDGGWTPMIWATE 501
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + VK+L++ G+D+N ++ + LH+A S ++ + LL A + ++P
Sbjct: 502 YKHVDLVKLLLSKGSDINIRDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSP 561
Query: 222 LHVAASLGSASCTKLLLNAGADV 244
LH+AA C L L+ +DV
Sbjct: 562 LHIAARENRYDCVVLFLSRDSDV 584
Score = 39.5 bits (88), Expect = 0.043
Identities = 40/161 (24%), Positives = 67/161 (41%), Gaps = 13/161 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E + L+ NG D Q +GG+ T ++WA L+ LL G D + D+
Sbjct: 472 EVVQYLLSNGQMDVNCQ----DDGGW---TPMIWATEYKHVDLVKLLLSKGSDINIRDNE 524
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + G + ++LL + + + +PLH AA CV + ++
Sbjct: 525 ENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGD---SPLHIAARENRYDCVVLFLSRD 581
Query: 177 ADVN-AGLSDRSPLHYAVLSDAPEVVKELLEA--GACPDTP 214
+DV +PL A L+ ++ +A + PD P
Sbjct: 582 SDVTLKNKEGETPLQCASLNSQVWSALQMSKALQDSAPDRP 622
Score = 35.9 bits (79), Expect = 0.52
Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ MLVD + + + + R+PLH A G DI +L+ AGA+ + TPL
Sbjct: 372 KVLLMLVDGIDPNFKMEHQNKRSPLHAAAEAGH--VDICHMLVQAGANIDTCSEDQRTPL 429
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYL 405
AA N V L+ G V + G + L ++ + +YL
Sbjct: 430 MEAAENNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYL 477
>BC126351-1|AAI26352.1| 467|Homo sapiens ASB10 protein protein.
Length = 467
Score = 112 bits (270), Expect = 4e-24
Identities = 82/223 (36%), Positives = 105/223 (47%), Gaps = 15/223 (6%)
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGAC 210
E TPLH AAS +++L+ A ++ R+ LH A + V LL AGA
Sbjct: 114 EELTTPLHVAASRGHTEVLRLLLRRRARPDSAPGGRTALHEACAAGHTACVHVLLVAGAD 173
Query: 211 PDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARL 270
P+ + PLH+ G+ C +LLL GA V + T LH+AA GH E A L
Sbjct: 174 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 233
Query: 271 LLDHGAHIDWPNFRGQTPLHL-------------ATLAQSLEVVEMLVDRCADVRAKDAD 317
LL GA D N G TPL AT A+ L++ +L+ AD A D D
Sbjct: 234 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 293
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
+ PLH A RG A + LLLS G N D G+TPLH A
Sbjct: 294 KQRPLHLACRRGHAA--VVELLLSCGVSANTMDYGGHTPLHCA 334
Score = 106 bits (255), Expect = 2e-22
Identities = 83/216 (38%), Positives = 107/216 (49%), Gaps = 14/216 (6%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH A EV++ LL A PD+ T LH A + G +C +LL AGAD
Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPDSAPG-GRTALHEACAAGHTACVHVLLVAGADPNI 176
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLV 305
A GK LHL G ECA LLL GA +D + + TPLH+A +E+ ++L+
Sbjct: 177 ADQDGKRP-LHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLL 235
Query: 306 DRCADVRAKDADGRTPLHGAI-VR----------GARACDIARLLLSAGADPNAADNFGY 354
R A A++A+G TPL A VR AR + LLLSAGAD +AAD
Sbjct: 236 RRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQ 295
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
PLH+A +A V LLL G GG + L
Sbjct: 296 RPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPL 331
Score = 89.4 bits (212), Expect = 4e-17
Identities = 89/245 (36%), Positives = 107/245 (43%), Gaps = 23/245 (9%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G E ++LLL A P+ S T LH A +A ACV VL+ GAD
Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPD----SAPGGRTALHEACAAGHTACVHVLLVAGAD 173
Query: 179 VNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTETPLHVAASLGSASCTKL 236
N D + PLH E + LL GA D + ETPLHVAA LG L
Sbjct: 174 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 233
Query: 237 LLNAGA--DVRAAMG-PGKATALHLAAE---DGHAECAR------LLLDHGAHIDWPNFR 284
LL GA D R A G A + + D A AR LLL GA D +
Sbjct: 234 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 293
Query: 285 GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC-----DIARLL 339
Q PLHLA VVE+L+ D G TPLH A+ A A + R L
Sbjct: 294 KQRPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRAL 353
Query: 340 LSAGA 344
L+ GA
Sbjct: 354 LNHGA 358
Score = 81.4 bits (192), Expect = 1e-14
Identities = 77/240 (32%), Positives = 110/240 (45%), Gaps = 24/240 (10%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G RTA+ AC G + + LL G DP+ D G+ LHL G+ EC +LLL GA
Sbjct: 147 GGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGAR 206
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAV------LS 195
+ S E + TPLH AA + +L+ GA +A ++ +PL A ++
Sbjct: 207 VD--GRSEEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAACDVRCQSIT 264
Query: 196 DAP-------EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
DA ++ LL AGA D + PLH+A G A+ +LLL+ G M
Sbjct: 265 DAEATTARCLQLCSLLLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSAN-TM 323
Query: 249 GPGKATALHLAAEDGHAECA-------RLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVV 301
G T LH A + A A R LL+HGA WP + +T +++EV+
Sbjct: 324 DYGGHTPLHCALQGPAAALAQSPEHVVRALLNHGAVRVWPGALPKVLERWSTCPRTIEVL 383
>AK125565-1|BAC86204.1| 452|Homo sapiens protein ( Homo sapiens
cDNA FLJ43577 fis, clone SKMUS2006394, weakly similar
to Mus musculus ankyrin repeat-containing protein Asb-4
mRNA. ).
Length = 452
Score = 112 bits (270), Expect = 4e-24
Identities = 82/223 (36%), Positives = 105/223 (47%), Gaps = 15/223 (6%)
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGAC 210
E TPLH AAS +++L+ A ++ R+ LH A + V LL AGA
Sbjct: 99 EELTTPLHVAASRGHTEVLRLLLRRRARPDSAPGGRTALHEACAAGHTACVHVLLVAGAD 158
Query: 211 PDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARL 270
P+ + PLH+ G+ C +LLL GA V + T LH+AA GH E A L
Sbjct: 159 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 218
Query: 271 LLDHGAHIDWPNFRGQTPLHL-------------ATLAQSLEVVEMLVDRCADVRAKDAD 317
LL GA D N G TPL AT A+ L++ +L+ AD A D D
Sbjct: 219 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 278
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
+ PLH A RG A + LLLS G N D G+TPLH A
Sbjct: 279 KQRPLHLACRRGHAA--VVELLLSCGVSANTMDYGGHTPLHCA 319
Score = 106 bits (255), Expect = 2e-22
Identities = 83/216 (38%), Positives = 107/216 (49%), Gaps = 14/216 (6%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH A EV++ LL A PD+ T LH A + G +C +LL AGAD
Sbjct: 103 TPLHVAASRGHTEVLRLLLRRRARPDSAPG-GRTALHEACAAGHTACVHVLLVAGADPNI 161
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLV 305
A GK LHL G ECA LLL GA +D + + TPLH+A +E+ ++L+
Sbjct: 162 ADQDGKRP-LHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLL 220
Query: 306 DRCADVRAKDADGRTPLHGAI-VR----------GARACDIARLLLSAGADPNAADNFGY 354
R A A++A+G TPL A VR AR + LLLSAGAD +AAD
Sbjct: 221 RRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQ 280
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
PLH+A +A V LLL G GG + L
Sbjct: 281 RPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPL 316
Score = 89.4 bits (212), Expect = 4e-17
Identities = 89/245 (36%), Positives = 107/245 (43%), Gaps = 23/245 (9%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G E ++LLL A P+ S T LH A +A ACV VL+ GAD
Sbjct: 103 TPLHVAASRGHTEVLRLLLRRRARPD----SAPGGRTALHEACAAGHTACVHVLLVAGAD 158
Query: 179 VNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTETPLHVAASLGSASCTKL 236
N D + PLH E + LL GA D + ETPLHVAA LG L
Sbjct: 159 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 218
Query: 237 LLNAGA--DVRAAMG-PGKATALHLAAE---DGHAECAR------LLLDHGAHIDWPNFR 284
LL GA D R A G A + + D A AR LLL GA D +
Sbjct: 219 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 278
Query: 285 GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC-----DIARLL 339
Q PLHLA VVE+L+ D G TPLH A+ A A + R L
Sbjct: 279 KQRPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRAL 338
Query: 340 LSAGA 344
L+ GA
Sbjct: 339 LNHGA 343
Score = 81.4 bits (192), Expect = 1e-14
Identities = 77/240 (32%), Positives = 110/240 (45%), Gaps = 24/240 (10%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G RTA+ AC G + + LL G DP+ D G+ LHL G+ EC +LLL GA
Sbjct: 132 GGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGAR 191
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAV------LS 195
+ S E + TPLH AA + +L+ GA +A ++ +PL A ++
Sbjct: 192 VD--GRSEEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPLLAACDVRCQSIT 249
Query: 196 DAP-------EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
DA ++ LL AGA D + PLH+A G A+ +LLL+ G M
Sbjct: 250 DAEATTARCLQLCSLLLSAGADADAADQDKQRPLHLACRRGHAAVVELLLSCGVSAN-TM 308
Query: 249 GPGKATALHLAAEDGHAECA-------RLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVV 301
G T LH A + A A R LL+HGA WP + +T +++EV+
Sbjct: 309 DYGGHTPLHCALQGPAAALAQSPEHVVRALLNHGAVRVWPGALPKVLERWSTCPRTIEVL 368
>AF417920-1|AAL59159.1| 429|Homo sapiens ASB-10 protein.
Length = 429
Score = 112 bits (270), Expect = 4e-24
Identities = 82/223 (36%), Positives = 105/223 (47%), Gaps = 15/223 (6%)
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGAC 210
E TPLH AAS +++L+ A ++ R+ LH A + V LL AGA
Sbjct: 114 EELTTPLHVAASRGHTEVLRLLLRRRARPDSAPGGRTALHEACAAGHTACVHVLLVAGAD 173
Query: 211 PDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARL 270
P+ + PLH+ G+ C +LLL GA V + T LH+AA GH E A L
Sbjct: 174 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 233
Query: 271 LLDHGAHIDWPNFRGQTPLHL-------------ATLAQSLEVVEMLVDRCADVRAKDAD 317
LL GA D N G TPL AT A+ L++ +L+ AD A D D
Sbjct: 234 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 293
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
+ PLH A RG A + LLLS G N D G+TPLH A
Sbjct: 294 KQRPLHLACRRGHAA--VVELLLSCGVSANTMDYGGHTPLHCA 334
Score = 106 bits (255), Expect = 2e-22
Identities = 83/216 (38%), Positives = 107/216 (49%), Gaps = 14/216 (6%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PLH A EV++ LL A PD+ T LH A + G +C +LL AGAD
Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPDSAPG-GRTALHEACAAGHTACVHVLLVAGADPNI 176
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLV 305
A GK LHL G ECA LLL GA +D + + TPLH+A +E+ ++L+
Sbjct: 177 ADQDGKRP-LHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADLLL 235
Query: 306 DRCADVRAKDADGRTPLHGAI-VR----------GARACDIARLLLSAGADPNAADNFGY 354
R A A++A+G TPL A VR AR + LLLSAGAD +AAD
Sbjct: 236 RRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQDKQ 295
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
PLH+A +A V LLL G GG + L
Sbjct: 296 RPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPL 331
Score = 89.4 bits (212), Expect = 4e-17
Identities = 89/245 (36%), Positives = 107/245 (43%), Gaps = 23/245 (9%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH++ G E ++LLL A P+ S T LH A +A ACV VL+ GAD
Sbjct: 118 TPLHVAASRGHTEVLRLLLRRRARPD----SAPGGRTALHEACAAGHTACVHVLLVAGAD 173
Query: 179 VNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPD-TPQVFTETPLHVAASLGSASCTKL 236
N D + PLH E + LL GA D + ETPLHVAA LG L
Sbjct: 174 PNIADQDGKRPLHLCRGPGTLECAELLLRFGARVDGRSEEEEETPLHVAARLGHVELADL 233
Query: 237 LLNAGA--DVRAAMG-PGKATALHLAAE---DGHAECAR------LLLDHGAHIDWPNFR 284
LL GA D R A G A + + D A AR LLL GA D +
Sbjct: 234 LLRRGACPDARNAEGWTPLLAACDVRCQSITDAEATTARCLQLCSLLLSAGADADAADQD 293
Query: 285 GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC-----DIARLL 339
Q PLHLA VVE+L+ D G TPLH A+ A A + R L
Sbjct: 294 KQRPLHLACRRGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRAL 353
Query: 340 LSAGA 344
L+ GA
Sbjct: 354 LNHGA 358
Score = 80.2 bits (189), Expect = 2e-14
Identities = 82/235 (34%), Positives = 105/235 (44%), Gaps = 31/235 (13%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G RTA+ AC G + + LL G DP+ D G+ LHL G+ EC +LLL GA
Sbjct: 147 GGRTALHEACAAGHTACVHVLLVAGADPNIADQDGKRPLHLCRGPGTLECAELLLRFGAR 206
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVV 201
+ S E + TPLH AA + +L+ GA +A ++ +PL
Sbjct: 207 VD--GRSEEEEETPLHVAARLGHVELADLLLRRGACPDARNAEGWTPL------------ 252
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
AC Q T+ A L S LLL+AGAD AA K LHLA
Sbjct: 253 -----LAACDVRCQSITDAEATTARCLQLCS---LLLSAGADADAA-DQDKQRPLHLACR 303
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLH------LATLAQSLE-VVEMLVDRCA 309
GHA LLL G + ++ G TPLH A LAQS E VV L++ A
Sbjct: 304 RGHAAVVELLLSCGVSANTMDYGGHTPLHCALQGPAAALAQSPEHVVRALLNHGA 358
>AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens
cDNA FLJ10421 fis, clone NT2RP1000202, weakly similar to
ANKYRIN. ).
Length = 445
Score = 112 bits (269), Expect = 5e-24
Identities = 85/272 (31%), Positives = 135/272 (49%), Gaps = 15/272 (5%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G LHL+ G + V++LL+ GA PN ++T + TPL A + +++L+ HG
Sbjct: 6 GFCALHLAASQGHWKIVQILLEAGADPN---ATTLEETTPLFSAVENGQIDVLRLLLQHG 62
Query: 177 ADVNA--GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
A+VN + + LH A + E++K LL GA + F TPL VAA G
Sbjct: 63 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 122
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID-WPNFRG-QTPLHLA 292
+L+++GA+V KAT L +AA++GH +C LLL GA D + N Q P+H A
Sbjct: 123 SILISSGANVN-CQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAA 181
Query: 293 TLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD-- 350
+++++L+ + +P++ A+ G C +LL G P+A
Sbjct: 182 AQMGHTKILDLLIPLTNRACDTGLNKVSPVYSAVFGGHEDC--LEILLRNGYSPDAQACL 239
Query: 351 NFGY-TPLHIAALN--EFSACVLLLLDYGGDV 379
FG+ +P+ +A EF V +LL YG +
Sbjct: 240 VFGFSSPVCMAFQKDCEFFGIVNILLKYGAQI 271
Score = 85.0 bits (201), Expect = 9e-16
Identities = 59/164 (35%), Positives = 86/164 (52%), Gaps = 4/164 (2%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AAS G ++LL AGAD A + T L A E+G + RLLL HGA+++
Sbjct: 10 LHLAASQGHWKIVQILLEAGADPNATTLE-ETTPLFSAVENGQIDVLRLLLQHGANVNGS 68
Query: 282 NFR-GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G LH A+ ++ E++++L+ + A+ +D G TPL A G + +L+
Sbjct: 69 HSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGK--LESLSILI 126
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTN 384
S+GA+ N TPL IAA + CV LLL G D L N
Sbjct: 127 SSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGADPDLYCN 170
Score = 62.1 bits (144), Expect = 7e-09
Identities = 65/250 (26%), Positives = 106/250 (42%), Gaps = 7/250 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G DP+ T L + G + ++LLL HGA+ N S + LH A+
Sbjct: 25 LLEAGADPNATTLEETTPLFSAVENGQIDVLRLLLQHGANVN--GSHSMCGWNSLHQASF 82
Query: 163 AKSLACVKVLIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
++ +K+L+ GA+ +PL A E + L+ +GA + + TP
Sbjct: 83 QENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATP 142
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDW 280
L +AA G C +LLL++GAD +H AA+ GH + LL+
Sbjct: 143 LFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACD 202
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDR--CADVRAKDADG-RTPLHGAIVRGARACDIAR 337
+P++ A + +E+L+ D +A G +P+ A + I
Sbjct: 203 TGLNKVSPVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSSPVCMAFQKDCEFFGIVN 262
Query: 338 LLLSAGADPN 347
+LL GA N
Sbjct: 263 ILLKYGAQIN 272
Score = 54.4 bits (125), Expect = 1e-06
Identities = 35/109 (32%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
F G LHLA ++V++L++ AD A + TPL A+ G D+ RLLL
Sbjct: 4 FEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFSAVENG--QIDVLRLLLQH 61
Query: 343 GADPNAADNF-GYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA+ N + + G+ LH A+ E + + LLL G + + + G++ L
Sbjct: 62 GANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPL 110
>AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein.
Length = 394
Score = 111 bits (267), Expect = 9e-24
Identities = 100/324 (30%), Positives = 147/324 (45%), Gaps = 18/324 (5%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
E++ G ++ + A + G L LL+ VD D D+ GRT L L+ G ECV+ L
Sbjct: 11 ESDSG-ATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEAL 69
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA----GLSDRSPLHYA 192
++ GA + + TK TPLH + C+++L+ + A ++PL A
Sbjct: 70 INQGA--SIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLA 127
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
V + V LLE A DT + T LH G C ++LL + G+
Sbjct: 128 VAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGR 187
Query: 253 ATALHLAAEDGHAECARLLLDHGAHID---WPNFRGQTPLHLATLAQSLEVVEMLVD-RC 308
T LH AA GHA LL + + + +G TPLH A + +E+L++ +C
Sbjct: 188 -TPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKC 246
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSA--GADPNAADNFGYTPLHIAALNEFS 366
R + TPLH AI+ C A LLL A + + D+ G TPLH AA +
Sbjct: 247 --FRKFIGNPFTPLHCAIINDHGNC--ASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHV 302
Query: 367 ACVLLLLDYGGDVTLRTNGGVSAL 390
C+ LLL + V N G +AL
Sbjct: 303 ECLQLLLRHSAPVNAVDNSGKTAL 326
Score = 106 bits (255), Expect = 2e-22
Identities = 99/298 (33%), Positives = 142/298 (47%), Gaps = 19/298 (6%)
Query: 95 GKSILLFKLLKMGVDPDELD--DA-GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
G ++ L LL++ +P+ +D DA G+T L L+ G + V LLL+ A+ +T D
Sbjct: 95 GHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDI--- 151
Query: 152 TKATPLHCAASAKSLACVKVLIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGAC 210
T LH CV++L+ + S R+PLHYA + ELL+ A
Sbjct: 152 LGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQM-AL 210
Query: 211 PDTPQVFTE----TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE 266
+ F + TPLH A G+ +C ++LL R +G T LH A + H
Sbjct: 211 SEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKC-FRKFIG-NPFTPLHCAIINDHGN 268
Query: 267 CARLLLD--HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
CA LLL + + + +G+TPLH A A +E +++L+ A V A D G+T L
Sbjct: 269 CASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMM 328
Query: 325 AIVRG-ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
A G A A DI L+ SA AD D TPLH+A C LL+LD D +L
Sbjct: 329 AAENGQAGAVDI--LVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESL 384
Score = 79.8 bits (188), Expect = 3e-14
Identities = 59/183 (32%), Positives = 87/183 (47%), Gaps = 7/183 (3%)
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
T++PLH+AA G ++LL + D+ G+ TAL LAA GH EC L++ GA
Sbjct: 17 TKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGR-TALDLAAFKGHTECVEALINQGAS 75
Query: 278 IDWP-NFRGQTPLHLATL---AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
I N +TPLH + + L ++ + D V KDA G+TPL A+ G
Sbjct: 76 IFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGH--I 133
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFI 393
D LLL A+ + D G T LH + CV +LL+ + + + G + L +
Sbjct: 134 DAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYA 193
Query: 394 VRR 396
R
Sbjct: 194 AAR 196
>X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein.
Length = 1001
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 445 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 503
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 504 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 563
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 564 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 623
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 624 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 677
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 475 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 534
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 535 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 593
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 594 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 651
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 652 ESYHDCVLLFLSRGANPELRNKEGDTA 678
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 460 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 516
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 517 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 576
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 577 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 635
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 636 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 677
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 456 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 513
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 514 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 546
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 556 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 608
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 609 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 665
Query: 177 AD 178
A+
Sbjct: 666 AN 667
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 615 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 674
Query: 150 TET 152
+T
Sbjct: 675 GDT 677
>BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 922
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 366 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 424
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 425 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 484
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 485 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 544
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 545 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 598
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 396 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 455
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 456 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 514
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 515 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 572
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 573 ESYHDCVLLFLSRGANPELRNKEGDTA 599
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 381 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 437
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 438 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 497
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 498 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 556
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 557 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 598
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 377 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 434
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 435 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 467
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 477 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 529
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 530 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 586
Query: 177 AD 178
A+
Sbjct: 587 AN 588
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 536 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 595
Query: 150 TET 152
+T
Sbjct: 596 GDT 598
>BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 888
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 332 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 390
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 391 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 450
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 451 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 510
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 511 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 564
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 362 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 421
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 422 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 480
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 481 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 538
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 539 ESYHDCVLLFLSRGANPELRNKEGDTA 565
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 347 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 403
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 404 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 463
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 464 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 522
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 523 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 564
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 343 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 400
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 401 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 433
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 443 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 495
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 496 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 552
Query: 177 AD 178
A+
Sbjct: 553 AN 554
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 502 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 561
Query: 150 TET 152
+T
Sbjct: 562 GDT 564
>BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase
protein.
Length = 1327
Score = 110 bits (264), Expect = 2e-23
Identities = 90/258 (34%), Positives = 117/258 (45%), Gaps = 23/258 (8%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
+TPLH AA ++ V+ L+ HGADV+A PLH A EV + L+ GA +
Sbjct: 685 STPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADV----RAAMGP----------------GK 252
++ TPLH AA+ G KLLL GAD R P G
Sbjct: 745 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGD 804
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A L A + A +L + R TPLHLA +LEV E L++ ADV
Sbjct: 805 AALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVN 864
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A+D G PLH A G DIA LL+ NA D + +TPLH AA + LL
Sbjct: 865 AQDKGGLIPLHNAASYGH--VDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 922
Query: 373 LDYGGDVTLRTNGGVSAL 390
L +G D T++ G + L
Sbjct: 923 LAHGADPTMKNQEGQTPL 940
Score = 103 bits (247), Expect = 2e-21
Identities = 102/289 (35%), Positives = 129/289 (44%), Gaps = 27/289 (9%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-G 182
+C G VK L+D A+ N D + K++PLH AA V+ L+ GA+V+A
Sbjct: 189 ACRNGDVSRVKRLVD-AANVNAKDMAGR-KSSPLHFAAGFGRKDVVEHLLQMGANVHARD 246
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
PLH A EVV LL GA P+ + TPLH AA G +LL GA
Sbjct: 247 DGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGA 306
Query: 243 DVRAAMGPGKATALHLAAEDGHA------------ECAR---------LLLDHGAHIDWP 281
D GK+ AL LA A E AR LL +
Sbjct: 307 DPNIRNTDGKS-ALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHAS 365
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ R TPLHLA + +V++L+ ADV AKD G PLH A G ++ LLL
Sbjct: 366 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY--EVTELLLK 423
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA NA D + +TPLH AA LLL +G D TL G SA+
Sbjct: 424 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAV 472
Score = 103 bits (246), Expect = 3e-21
Identities = 91/275 (33%), Positives = 121/275 (44%), Gaps = 17/275 (6%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
+A G+ ++ LL+MG + DD G LH +C G E V LLL GA PN D+
Sbjct: 222 FAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDN- 280
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGA 209
TPLH AA + VL+ HGAD N +D + L A K +L
Sbjct: 281 --WNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGK----SALDLADPSAKAVL---- 330
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
T + + L A S LL + A+ G K+T LHLAA +
Sbjct: 331 ---TGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR-KSTPLHLAAGYNRVRIVQ 386
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL HGA + + G PLH A EV E+L+ A V A D TPLH A +
Sbjct: 387 LLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASK- 445
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
++ LLLS GADP + G + + +A E
Sbjct: 446 -NRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPE 479
Score = 100 bits (240), Expect = 2e-20
Identities = 88/270 (32%), Positives = 119/270 (44%), Gaps = 21/270 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 703 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADL---WKFTPLHEAAA 759
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL D +++LL A
Sbjct: 760 KGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTD--IQDLLRGDAA----------- 806
Query: 222 LHVAASLGS-ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G A KL + R G +T LHLAA + E A LL+HGA ++
Sbjct: 807 LLDAAKKGCLARVQKLCTPENINCRDTQGRN-STPLHLAAGYNNLEVAEYLLEHGADVNA 865
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A +++ +L+ V A D TPLH A +G + LLL
Sbjct: 866 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKG--RTQLCALLL 923
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVL 370
+ GADP + G TPL +A ++ A ++
Sbjct: 924 AHGADPTMKNQEGQTPLDLATADDIRALLI 953
Score = 93.9 bits (223), Expect = 2e-18
Identities = 96/335 (28%), Positives = 141/335 (42%), Gaps = 32/335 (9%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K G + LD G+T LH + L G + +LLL +G+ P+ T A+
Sbjct: 577 LHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT--------AA 628
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGA--CPDTPQVFTET 220
V+ +++ + D L + D E VK+L + C D + T
Sbjct: 629 QMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDL-ETVKQLCSSQNVNCRDLEGRHS-T 686
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH AA S + LL+ GADV A G LH A GH E A LL+ HGA ++
Sbjct: 687 PLHFAAGYNRVSVVEYLLHHGADVHAK-DKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL----------------HG 324
+ TPLH A E+ ++L+ AD K+ DG TPL
Sbjct: 746 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDA 805
Query: 325 AIVRGARACDIARL-LLSAGADPNAADNFG--YTPLHIAALNEFSACVLLLLDYGGDVTL 381
A++ A+ +AR+ L + N D G TPLH+AA LL++G DV
Sbjct: 806 ALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 865
Query: 382 RTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSE 416
+ GG+ L I L K++ V+ ++
Sbjct: 866 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 900
Score = 91.1 bits (216), Expect = 1e-17
Identities = 90/291 (30%), Positives = 136/291 (46%), Gaps = 26/291 (8%)
Query: 119 TCLHLSCLVGS-----EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
T LH C V S ++ +LLL GA+ N + TPLH AA ++VL
Sbjct: 524 TALH--CAVASLHPKRKQVTELLLRKGANVN---EKNKDFMTPLHVAAERAHNDVMEVLH 578
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
HGA +NA ++ LH A L+ + + LL G+ P + T AA +G+ +
Sbjct: 579 KHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEA 634
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ--TPLH 290
++L + +R + + L A++ G E + L +++ + G+ TPLH
Sbjct: 635 VQQIL-SESTPIRTSDVDYR---LLEASKAGDLETVKQLCS-SQNVNCRDLEGRHSTPLH 689
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A + VVE L+ ADV AKD G PLH A G ++A LL+ GA N AD
Sbjct: 690 FAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHY--EVAELLVRHGASVNVAD 747
Query: 351 NFGYTPLH-IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
+ +TPLH AA ++ C LLL +G D T + G + L + D+
Sbjct: 748 LWKFTPLHEAAAKGKYEIC-KLLLKHGADPTKKNRDGNTPLDLVKEGDTDI 797
Score = 84.2 bits (199), Expect = 2e-15
Identities = 78/258 (30%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E + T LH++ + +++L HGA N D+ +T LH AA
Sbjct: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTA---LHRAAL 600
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
A L ++L+++G+D S S + E V+++L T V + L
Sbjct: 601 AGHLQTCRLLLSYGSDP----SIISLQGFTAAQMGNEAVQQILSESTPIRTSDV--DYRL 654
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWP 281
A+ G K L ++ +V G+ +T LH AA LL HGA +
Sbjct: 655 LEASKAGDLETVKQLCSS-QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 713
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 714 DKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKG--KYEICKLLLK 771
Query: 342 AGADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 772 HGADPTKKNRDGNTPLDL 789
Score = 48.8 bits (111), Expect = 7e-05
Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 11/164 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA-TPLHCAA 161
LL+ G D + D G LH + G + LL+ + NT ++T+ A TPLH AA
Sbjct: 856 LLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKY----NTCVNATDKWAFTPLHEAA 911
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT-PQVFTE 219
+L+AHGAD + ++PL A D ++ LL P+ P F
Sbjct: 912 QKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADD----IRALLIDAMPPEALPTCFKP 967
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
V+ASL S + T L+A + + GP A+ A+ G
Sbjct: 968 QATVVSASLISPASTPSCLSAASSIDNLTGPLAGLAVGGASNAG 1011
>BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein.
Length = 1198
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 642 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 700
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 701 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 760
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 761 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 820
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 821 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 874
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 672 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 731
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 732 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 790
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 791 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 848
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 849 ESYHDCVLLFLSRGANPELRNKEGDTA 875
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 657 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 713
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 714 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 773
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 774 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 832
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 833 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 874
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 653 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 710
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 711 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 743
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 753 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 805
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 806 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 862
Query: 177 AD 178
A+
Sbjct: 863 AN 864
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 812 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 871
Query: 150 TET 152
+T
Sbjct: 872 GDT 874
>BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein.
Length = 1001
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 445 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 503
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 504 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 563
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 564 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 623
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 624 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 677
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 475 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 534
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 535 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 593
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 594 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 651
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 652 ESYHDCVLLFLSRGANPELRNKEGDTA 678
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 460 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 516
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 517 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 576
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 577 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 635
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 636 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 677
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 456 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 513
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 514 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 546
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 556 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 608
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 609 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 665
Query: 177 AD 178
A+
Sbjct: 666 AN 667
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 615 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 674
Query: 150 TET 152
+T
Sbjct: 675 GDT 677
>BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein.
Length = 1209
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 653 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 711
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 712 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 771
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 772 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 831
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 832 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 885
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 683 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 742
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 743 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 801
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 802 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 859
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 860 ESYHDCVLLFLSRGANPELRNKEGDTA 886
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 668 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 724
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 725 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 784
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 785 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 843
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 844 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 885
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 664 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 721
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 722 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 754
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 764 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 816
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 817 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 873
Query: 177 AD 178
A+
Sbjct: 874 AN 875
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 823 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 882
Query: 150 TET 152
+T
Sbjct: 883 GDT 885
>BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein.
Length = 1043
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 487 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 545
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 546 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 605
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 606 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 665
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 666 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 719
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 517 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 576
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 577 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 635
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 636 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 693
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 694 ESYHDCVLLFLSRGANPELRNKEGDTA 720
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 502 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 558
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 559 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 618
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 619 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 677
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 678 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 719
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 498 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 555
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 556 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 588
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 598 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 650
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 651 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 707
Query: 177 AD 178
A+
Sbjct: 708 AN 709
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 657 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 716
Query: 150 TET 152
+T
Sbjct: 717 GDT 719
>BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 445 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 503
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 504 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 563
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 564 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 623
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 624 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 677
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 475 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 534
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 535 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 593
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 594 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 651
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 652 ESYHDCVLLFLSRGANPELRNKEGDTA 678
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 460 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 516
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 517 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 576
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 577 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 635
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 636 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 677
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 456 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 513
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 514 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 546
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 556 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 608
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 609 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 665
Query: 177 AD 178
A+
Sbjct: 666 AN 667
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 615 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 674
Query: 150 TET 152
+T
Sbjct: 675 GDT 677
>AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1210
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 654 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 712
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 713 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 772
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 773 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 832
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 833 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 886
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 684 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 743
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 744 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 802
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 803 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 860
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 861 ESYHDCVLLFLSRGANPELRNKEGDTA 887
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 669 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 725
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 726 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 785
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 786 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 844
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 845 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 886
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 665 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 722
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 723 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 755
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 765 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 817
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 818 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 874
Query: 177 AD 178
A+
Sbjct: 875 AN 876
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 824 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 883
Query: 150 TET 152
+T
Sbjct: 884 GDT 886
>AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1176
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 620 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 678
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 679 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 738
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 739 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 798
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 799 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 852
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 650 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 709
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 710 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 768
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 769 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 826
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 827 ESYHDCVLLFLSRGANPELRNKEGDTA 853
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 635 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 691
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 692 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 751
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 752 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 810
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 811 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 852
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 631 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 688
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 689 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 721
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 731 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 783
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 784 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 840
Query: 177 AD 178
A+
Sbjct: 841 AN 842
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 790 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 849
Query: 150 TET 152
+T
Sbjct: 850 GDT 852
>AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 654 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 712
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 713 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 772
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 773 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 832
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 833 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 886
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 684 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 743
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 744 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 802
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 803 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 860
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 861 ESYHDCVLLFLSRGANPELRNKEGDTA 887
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 669 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 725
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 726 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 785
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 786 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 844
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 845 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 886
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 665 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 722
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 723 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 755
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 765 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 817
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 818 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 874
Query: 177 AD 178
A+
Sbjct: 875 AN 876
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 824 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 883
Query: 150 TET 152
+T
Sbjct: 884 GDT 886
>AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 620 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 678
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 679 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 738
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 739 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 798
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 799 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 852
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 650 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 709
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 710 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 768
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 769 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 826
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 827 ESYHDCVLLFLSRGANPELRNKEGDTA 853
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 635 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 691
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 692 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 751
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 752 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 810
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 811 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 852
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 631 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 688
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 689 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 721
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 731 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 783
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 784 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 840
Query: 177 AD 178
A+
Sbjct: 841 AN 842
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 790 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 849
Query: 150 TET 152
+T
Sbjct: 850 GDT 852
>AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 711 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 769
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 770 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 829
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 830 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 889
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 890 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 943
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 741 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 800
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 801 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 859
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 860 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 917
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 918 ESYHDCVLLFLSRGANPELRNKEGDTA 944
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 726 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 782
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 783 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 842
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 843 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 901
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 902 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 943
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 722 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 779
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 780 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 812
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 822 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 874
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 875 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 931
Query: 177 AD 178
A+
Sbjct: 932 AN 933
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 881 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 940
Query: 150 TET 152
+T
Sbjct: 941 GDT 943
>AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 677 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 735
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 736 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 795
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 796 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 855
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 856 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 909
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 707 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 766
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 767 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 825
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 826 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 883
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 884 ESYHDCVLLFLSRGANPELRNKEGDTA 910
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 692 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 748
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 749 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 808
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 809 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 867
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 868 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 909
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 688 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 745
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 746 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 778
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 788 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 840
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 841 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 897
Query: 177 AD 178
A+
Sbjct: 898 AN 899
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 847 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 906
Query: 150 TET 152
+T
Sbjct: 907 GDT 909
>AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 620 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 678
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 679 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 738
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 739 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 798
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 799 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 852
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 650 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 709
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 710 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 768
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 769 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 826
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 827 ESYHDCVLLFLSRGANPELRNKEGDTA 853
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 635 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 691
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 692 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 751
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 752 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 810
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 811 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 852
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 631 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 688
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 689 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 721
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 731 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 783
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 784 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 840
Query: 177 AD 178
A+
Sbjct: 841 AN 842
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 790 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 849
Query: 150 TET 152
+T
Sbjct: 850 GDT 852
>AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 654 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 712
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 713 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 772
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 773 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 832
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 833 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 886
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 684 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 743
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 744 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 802
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 803 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 860
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 861 ESYHDCVLLFLSRGANPELRNKEGDTA 887
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 669 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 725
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 726 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 785
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 786 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 844
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 845 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 886
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 665 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 722
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 723 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 755
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 765 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 817
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 818 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 874
Query: 177 AD 178
A+
Sbjct: 875 AN 876
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 824 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 883
Query: 150 TET 152
+T
Sbjct: 884 GDT 886
>AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 711 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 769
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 770 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 829
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 830 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 889
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 890 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 943
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 741 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 800
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 801 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 859
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 860 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 917
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 918 ESYHDCVLLFLSRGANPELRNKEGDTA 944
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 726 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 782
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 783 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 842
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 843 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 901
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 902 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 943
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 722 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 779
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 780 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 812
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 822 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 874
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 875 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 931
Query: 177 AD 178
A+
Sbjct: 932 AN 933
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 881 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 940
Query: 150 TET 152
+T
Sbjct: 941 GDT 943
>AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 677 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 735
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 736 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 795
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 796 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 855
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 856 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 909
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 707 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 766
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 767 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 825
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 826 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 883
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 884 ESYHDCVLLFLSRGANPELRNKEGDTA 910
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 692 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 748
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 749 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 808
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 809 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 867
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 868 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 909
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 688 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 745
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 746 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 778
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 788 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 840
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 841 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 897
Query: 177 AD 178
A+
Sbjct: 898 AN 899
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 847 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 906
Query: 150 TET 152
+T
Sbjct: 907 GDT 909
>AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein.
Length = 1210
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 654 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 712
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 713 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 772
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 773 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 832
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 833 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 886
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 684 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 743
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 744 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 802
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 803 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 860
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 861 ESYHDCVLLFLSRGANPELRNKEGDTA 887
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 669 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 725
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 726 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 785
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 786 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 844
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 845 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 886
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 665 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 722
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 723 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 755
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 765 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 817
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 818 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 874
Query: 177 AD 178
A+
Sbjct: 875 AN 876
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 824 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 883
Query: 150 TET 152
+T
Sbjct: 884 GDT 886
>AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 110 bits (264), Expect = 2e-23
Identities = 79/236 (33%), Positives = 116/236 (49%), Gaps = 4/236 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 445 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 503
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 504 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 563
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
G A G T + AAE H E R+LL GA + + LH A+ S
Sbjct: 564 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAA 623
Query: 300 VVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
+ E+L++ D+ A + G TPLH A C + L LS GA+P + G T
Sbjct: 624 IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKEGDT 677
Score = 99 bits (238), Expect = 3e-20
Identities = 73/207 (35%), Positives = 102/207 (49%), Gaps = 4/207 (1%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 475 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 534
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 535 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 593
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G TPLHIAA
Sbjct: 594 MLLTRGADVTLTDNEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDTPLHIAAR 651
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ CVLL L G + LR G +A
Sbjct: 652 ESYHDCVLLFLSRGANPELRNKEGDTA 678
Score = 67.7 bits (158), Expect = 1e-10
Identities = 65/222 (29%), Positives = 97/222 (43%), Gaps = 8/222 (3%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 460 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 516
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 517 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 576
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
TP+ AA ++LL GADV + LH A+ G A A +LL+ +
Sbjct: 577 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDL 635
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 636 HAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 677
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 456 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 513
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 514 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 546
Score = 40.7 bits (91), Expect = 0.018
Identities = 34/122 (27%), Positives = 54/122 (44%), Gaps = 10/122 (8%)
Query: 57 EEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
E +S+L+ G D Q + GG+ T I+WA ++ LL G D D+
Sbjct: 556 EMVSLLLSTGQVDVNAQDS----GGW---TPIIWAAEHKHIEVIRMLLTRGADVTLTDNE 608
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
CLH + GS ++LL+ + + + TPLH AA CV + ++ G
Sbjct: 609 ENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGD---TPLHIAARESYHDCVLLFLSRG 665
Query: 177 AD 178
A+
Sbjct: 666 AN 667
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 615 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 674
Query: 150 TET 152
+T
Sbjct: 675 GDT 677
>AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1094
Score = 110 bits (264), Expect = 2e-23
Identities = 90/258 (34%), Positives = 117/258 (45%), Gaps = 23/258 (8%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
+TPLH AA ++ V+ L+ HGADV+A PLH A EV + L+ GA +
Sbjct: 452 STPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 511
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADV----RAAMGP----------------GK 252
++ TPLH AA+ G KLLL GAD R P G
Sbjct: 512 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLKGD 571
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A L A + A +L + R TPLHLA +LEV E L++ ADV
Sbjct: 572 AALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVN 631
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A+D G PLH A G DIA LL+ NA D + +TPLH AA + LL
Sbjct: 632 AQDKGGLIPLHNAASYGH--VDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 689
Query: 373 LDYGGDVTLRTNGGVSAL 390
L +G D T++ G + L
Sbjct: 690 LAHGADPTMKNQEGQTPL 707
Score = 101 bits (241), Expect = 1e-20
Identities = 88/270 (32%), Positives = 120/270 (44%), Gaps = 21/270 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 470 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADL---WKFTPLHEAAA 526
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL D +++LL+ A
Sbjct: 527 KGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTD--IQDLLKGDAA----------- 573
Query: 222 LHVAASLGS-ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G A KL + R G +T LHLAA + E A LL+HGA ++
Sbjct: 574 LLDAAKKGCLARVQKLCTPENINCRDTQGRN-STPLHLAAGYNNLEVAEYLLEHGADVNA 632
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A +++ +L+ V A D TPLH A +G + LLL
Sbjct: 633 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKG--RTQLCALLL 690
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVL 370
+ GADP + G TPL +A ++ A ++
Sbjct: 691 AHGADPTMKNQEGQTPLDLATADDIRALLI 720
Score = 100 bits (240), Expect = 2e-20
Identities = 89/262 (33%), Positives = 115/262 (43%), Gaps = 17/262 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+MG + DD G LH +C G E V LLL GA PN D+ TPLH AA
Sbjct: 2 LLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDN---WNYTPLHEAAI 58
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
+ VL+ HGAD N +D + L A K +L T + + L
Sbjct: 59 KGKIDVCIVLLQHGADPNIRNTDGK----SALDLADPSAKAVL-------TGEYKKDELL 107
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
A S LL + A+ G K+T LHLAA +LLL HGA + +
Sbjct: 108 EAARSGNEEKLMALLTPLNVNCHASDGR-KSTPLHLAAGYNRVRIVQLLLQHGADVHAKD 166
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
G PLH A EV E+L+ A V A D TPLH A + ++ LLLS
Sbjct: 167 KGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASK--NRVEVCSLLLSH 224
Query: 343 GADPNAADNFGYTPLHIAALNE 364
GADP + G + + +A E
Sbjct: 225 GADPTLVNCHGKSAVDMAPTPE 246
Score = 93.9 bits (223), Expect = 2e-18
Identities = 96/335 (28%), Positives = 141/335 (42%), Gaps = 32/335 (9%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K G + LD G+T LH + L G + +LLL +G+ P+ T A+
Sbjct: 344 LHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT--------AA 395
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGA--CPDTPQVFTET 220
V+ +++ + D L + D E VK+L + C D + T
Sbjct: 396 QMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDL-ETVKQLCSSQNVNCRDLEGRHS-T 453
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH AA S + LL+ GADV A G LH A GH E A LL+ HGA ++
Sbjct: 454 PLHFAAGYNRVSVVEYLLHHGADVHAK-DKGGLVPLHNACSYGHYEVAELLVRHGASVNV 512
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL----------------HG 324
+ TPLH A E+ ++L+ AD K+ DG TPL
Sbjct: 513 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDA 572
Query: 325 AIVRGARACDIARL-LLSAGADPNAADNFG--YTPLHIAALNEFSACVLLLLDYGGDVTL 381
A++ A+ +AR+ L + N D G TPLH+AA LL++G DV
Sbjct: 573 ALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 632
Query: 382 RTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSE 416
+ GG+ L I L K++ V+ ++
Sbjct: 633 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 667
Score = 91.1 bits (216), Expect = 1e-17
Identities = 90/291 (30%), Positives = 136/291 (46%), Gaps = 26/291 (8%)
Query: 119 TCLHLSCLVGS-----EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
T LH C V S ++ +LLL GA+ N + TPLH AA ++VL
Sbjct: 291 TALH--CAVASLHPKRKQVTELLLRKGANVN---EKNKDFMTPLHVAAERAHNDVMEVLH 345
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
HGA +NA ++ LH A L+ + + LL G+ P + T AA +G+ +
Sbjct: 346 KHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEA 401
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ--TPLH 290
++L + +R + + L A++ G E + L +++ + G+ TPLH
Sbjct: 402 VQQIL-SESTPIRTSDVDYR---LLEASKAGDLETVKQLCS-SQNVNCRDLEGRHSTPLH 456
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A + VVE L+ ADV AKD G PLH A G ++A LL+ GA N AD
Sbjct: 457 FAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHY--EVAELLVRHGASVNVAD 514
Query: 351 NFGYTPLH-IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
+ +TPLH AA ++ C LLL +G D T + G + L + D+
Sbjct: 515 LWKFTPLHEAAAKGKYEIC-KLLLKHGADPTKKNRDGNTPLDLVKEGDTDI 564
Score = 89.8 bits (213), Expect = 3e-17
Identities = 80/237 (33%), Positives = 106/237 (44%), Gaps = 18/237 (7%)
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTP 214
PLH A S V +L+ GAD NA + + +PLH A + +V LL+ GA P+
Sbjct: 19 PLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIR 78
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLD 273
++ L +A A T G K L AA G+ E LL
Sbjct: 79 NTDGKSALDLADPSAKAVLT--------------GEYKKDELLEAARSGNEEKLMALLTP 124
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+ + R TPLHLA + +V++L+ ADV AKD G PLH A G
Sbjct: 125 LNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY-- 182
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
++ LLL GA NA D + +TPLH AA LLL +G D TL G SA+
Sbjct: 183 EVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAV 239
Score = 84.2 bits (199), Expect = 2e-15
Identities = 78/258 (30%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E + T LH++ + +++L HGA N D+ +T LH AA
Sbjct: 311 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTA---LHRAAL 367
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
A L ++L+++G+D S S + E V+++L T V + L
Sbjct: 368 AGHLQTCRLLLSYGSDP----SIISLQGFTAAQMGNEAVQQILSESTPIRTSDV--DYRL 421
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWP 281
A+ G K L ++ +V G+ +T LH AA LL HGA +
Sbjct: 422 LEASKAGDLETVKQLCSS-QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 480
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 481 DKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKG--KYEICKLLLK 538
Query: 342 AGADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 539 HGADPTKKNRDGNTPLDL 556
Score = 83.4 bits (197), Expect = 3e-15
Identities = 89/295 (30%), Positives = 125/295 (42%), Gaps = 22/295 (7%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
L+ L + V+ D T LHL+ V+LLL HGA + D PLH
Sbjct: 118 LMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG---GLVPLH 174
Query: 159 CAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
A S ++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 175 NACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP------ 228
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
T H +++ A +L + + + L A E A+ + L +
Sbjct: 229 TLVNCHGKSAVDMAPTPELRERLTYEFKG------HSLLQAAREADLAKVKKTLALEIIN 282
Query: 278 IDWPNFRGQTPLHLATLA---QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACD 334
P +T LH A + + +V E+L+ + A+V K+ D TPLH A R D
Sbjct: 283 FKQPQSH-ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHN--D 339
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ +L GA NA D G T LH AAL LLL YG D ++ + G +A
Sbjct: 340 VMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTA 394
Score = 75.4 bits (177), Expect = 7e-13
Identities = 71/231 (30%), Positives = 97/231 (41%), Gaps = 17/231 (7%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + ++ LL G DP+ D+ T LH + + G + +LL HGA PN +T
Sbjct: 23 ACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNI--RNT 80
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL-EAGA 209
+ K+ SAK+ V G + L A S E + LL
Sbjct: 81 DGKSALDLADPSAKA-------------VLTGEYKKDELLEAARSGNEEKLMALLTPLNV 127
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
TPLH+AA +LLL GADV A G LH A GH E
Sbjct: 128 NCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVH-AKDKGGLVPLHNACSYGHYEVTE 186
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
LLL HGA ++ + TPLH A +EV +L+ AD + G++
Sbjct: 187 LLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKS 237
Score = 68.9 bits (161), Expect = 6e-11
Identities = 38/87 (43%), Positives = 49/87 (56%), Gaps = 2/87 (2%)
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ A+V A+D G PLH A G ++ LLL GADPNA DN+ YTPLH AA+
Sbjct: 2 LLQMGANVHARDDGGLIPLHNACSFGH--AEVVSLLLCQGADPNARDNWNYTPLHEAAIK 59
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
++LL +G D +R G SAL
Sbjct: 60 GKIDVCIVLLQHGADPNIRNTDGKSAL 86
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 11/164 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA-TPLHCAA 161
LL+ G D + D G LH + G + LL+ + NT ++T+ A TPLH AA
Sbjct: 623 LLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKY----NTCVNATDKWAFTPLHEAA 678
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT-PQVFTE 219
+L+AHGAD + ++PL A D ++ LL P+ P F
Sbjct: 679 QKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADD----IRALLIDAMPPEALPTCFKP 734
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
V+ASL S + T L+A + + GP A+ A+ G
Sbjct: 735 QATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAG 778
>AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting
ankyrin-related ADP-ribose polymerase protein.
Length = 1327
Score = 110 bits (264), Expect = 2e-23
Identities = 90/258 (34%), Positives = 117/258 (45%), Gaps = 23/258 (8%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
+TPLH AA ++ V+ L+ HGADV+A PLH A EV + L+ GA +
Sbjct: 685 STPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 744
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADV----RAAMGP----------------GK 252
++ TPLH AA+ G KLLL GAD R P G
Sbjct: 745 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLKGD 804
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A L A + A +L + R TPLHLA +LEV E L++ ADV
Sbjct: 805 AALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVN 864
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A+D G PLH A G DIA LL+ NA D + +TPLH AA + LL
Sbjct: 865 AQDKGGLIPLHNAASYGH--VDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 922
Query: 373 LDYGGDVTLRTNGGVSAL 390
L +G D T++ G + L
Sbjct: 923 LAHGADPTMKNQEGQTPL 940
Score = 103 bits (247), Expect = 2e-21
Identities = 102/289 (35%), Positives = 129/289 (44%), Gaps = 27/289 (9%)
Query: 124 SCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-G 182
+C G VK L+D A+ N D + K++PLH AA V+ L+ GA+V+A
Sbjct: 189 ACRNGDVSRVKRLVD-AANVNAKDMAGR-KSSPLHFAAGFGRKDVVEHLLQMGANVHARD 246
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
PLH A EVV LL GA P+ + TPLH AA G +LL GA
Sbjct: 247 DGGLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGA 306
Query: 243 DVRAAMGPGKATALHLAAEDGHA------------ECAR---------LLLDHGAHIDWP 281
D GK+ AL LA A E AR LL +
Sbjct: 307 DPNIRNTDGKS-ALDLADPSAKAVLTGEYKKDELLEAARSGNEEKLMALLTPLNVNCHAS 365
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ R TPLHLA + +V++L+ ADV AKD G PLH A G ++ LLL
Sbjct: 366 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY--EVTELLLK 423
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
GA NA D + +TPLH AA LLL +G D TL G SA+
Sbjct: 424 HGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAV 472
Score = 103 bits (246), Expect = 3e-21
Identities = 91/275 (33%), Positives = 121/275 (44%), Gaps = 17/275 (6%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
+A G+ ++ LL+MG + DD G LH +C G E V LLL GA PN D+
Sbjct: 222 FAAGFGRKDVVEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADPNARDN- 280
Query: 150 TETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGA 209
TPLH AA + VL+ HGAD N +D + L A K +L
Sbjct: 281 --WNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGK----SALDLADPSAKAVL---- 330
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
T + + L A S LL + A+ G K+T LHLAA +
Sbjct: 331 ---TGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR-KSTPLHLAAGYNRVRIVQ 386
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
LLL HGA + + G PLH A EV E+L+ A V A D TPLH A +
Sbjct: 387 LLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASK- 445
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
++ LLLS GADP + G + + +A E
Sbjct: 446 -NRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPE 479
Score = 101 bits (241), Expect = 1e-20
Identities = 88/270 (32%), Positives = 120/270 (44%), Gaps = 21/270 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 703 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADL---WKFTPLHEAAA 759
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL D +++LL+ A
Sbjct: 760 KGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTD--IQDLLKGDAA----------- 806
Query: 222 LHVAASLGS-ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G A KL + R G +T LHLAA + E A LL+HGA ++
Sbjct: 807 LLDAAKKGCLARVQKLCTPENINCRDTQGRN-STPLHLAAGYNNLEVAEYLLEHGADVNA 865
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A +++ +L+ V A D TPLH A +G + LLL
Sbjct: 866 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKG--RTQLCALLL 923
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVL 370
+ GADP + G TPL +A ++ A ++
Sbjct: 924 AHGADPTMKNQEGQTPLDLATADDIRALLI 953
Score = 93.9 bits (223), Expect = 2e-18
Identities = 96/335 (28%), Positives = 141/335 (42%), Gaps = 32/335 (9%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K G + LD G+T LH + L G + +LLL +G+ P+ T A+
Sbjct: 577 LHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT--------AA 628
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGA--CPDTPQVFTET 220
V+ +++ + D L + D E VK+L + C D + T
Sbjct: 629 QMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDL-ETVKQLCSSQNVNCRDLEGRHS-T 686
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH AA S + LL+ GADV A G LH A GH E A LL+ HGA ++
Sbjct: 687 PLHFAAGYNRVSVVEYLLHHGADVHAK-DKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL----------------HG 324
+ TPLH A E+ ++L+ AD K+ DG TPL
Sbjct: 746 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLKGDA 805
Query: 325 AIVRGARACDIARL-LLSAGADPNAADNFG--YTPLHIAALNEFSACVLLLLDYGGDVTL 381
A++ A+ +AR+ L + N D G TPLH+AA LL++G DV
Sbjct: 806 ALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 865
Query: 382 RTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSE 416
+ GG+ L I L K++ V+ ++
Sbjct: 866 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 900
Score = 91.1 bits (216), Expect = 1e-17
Identities = 90/291 (30%), Positives = 136/291 (46%), Gaps = 26/291 (8%)
Query: 119 TCLHLSCLVGS-----EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
T LH C V S ++ +LLL GA+ N + TPLH AA ++VL
Sbjct: 524 TALH--CAVASLHPKRKQVTELLLRKGANVN---EKNKDFMTPLHVAAERAHNDVMEVLH 578
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
HGA +NA ++ LH A L+ + + LL G+ P + T AA +G+ +
Sbjct: 579 KHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEA 634
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ--TPLH 290
++L + +R + + L A++ G E + L +++ + G+ TPLH
Sbjct: 635 VQQIL-SESTPIRTSDVDYR---LLEASKAGDLETVKQLCS-SQNVNCRDLEGRHSTPLH 689
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A + VVE L+ ADV AKD G PLH A G ++A LL+ GA N AD
Sbjct: 690 FAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHY--EVAELLVRHGASVNVAD 747
Query: 351 NFGYTPLH-IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
+ +TPLH AA ++ C LLL +G D T + G + L + D+
Sbjct: 748 LWKFTPLHEAAAKGKYEIC-KLLLKHGADPTKKNRDGNTPLDLVKEGDTDI 797
Score = 84.2 bits (199), Expect = 2e-15
Identities = 78/258 (30%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E + T LH++ + +++L HGA N D+ +T LH AA
Sbjct: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTA---LHRAAL 600
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
A L ++L+++G+D S S + E V+++L T V + L
Sbjct: 601 AGHLQTCRLLLSYGSDP----SIISLQGFTAAQMGNEAVQQILSESTPIRTSDV--DYRL 654
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWP 281
A+ G K L ++ +V G+ +T LH AA LL HGA +
Sbjct: 655 LEASKAGDLETVKQLCSS-QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 713
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 714 DKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKG--KYEICKLLLK 771
Query: 342 AGADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 772 HGADPTKKNRDGNTPLDL 789
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 11/164 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA-TPLHCAA 161
LL+ G D + D G LH + G + LL+ + NT ++T+ A TPLH AA
Sbjct: 856 LLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKY----NTCVNATDKWAFTPLHEAA 911
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT-PQVFTE 219
+L+AHGAD + ++PL A D ++ LL P+ P F
Sbjct: 912 QKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADD----IRALLIDAMPPEALPTCFKP 967
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
V+ASL S + T L+A + + GP A+ A+ G
Sbjct: 968 QATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAG 1011
>AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase,
TRF1-interacting ankyrin-related ADP-ribose polymerase
variant protein.
Length = 1055
Score = 110 bits (264), Expect = 2e-23
Identities = 90/258 (34%), Positives = 117/258 (45%), Gaps = 23/258 (8%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPD 212
+TPLH AA ++ V+ L+ HGADV+A PLH A EV + L+ GA +
Sbjct: 413 STPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVN 472
Query: 213 TPQVFTETPLHVAASLGSASCTKLLLNAGADV----RAAMGP----------------GK 252
++ TPLH AA+ G KLLL GAD R P G
Sbjct: 473 VADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGD 532
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A L A + A +L + R TPLHLA +LEV E L++ ADV
Sbjct: 533 AALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVN 592
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A+D G PLH A G DIA LL+ NA D + +TPLH AA + LL
Sbjct: 593 AQDKGGLIPLHNAASYGH--VDIAALLIKYNTCVNATDKWAFTPLHEAAQKGRTQLCALL 650
Query: 373 LDYGGDVTLRTNGGVSAL 390
L +G D T++ G + L
Sbjct: 651 LAHGADPTMKNQEGQTPL 668
Score = 100 bits (240), Expect = 2e-20
Identities = 88/270 (32%), Positives = 119/270 (44%), Gaps = 21/270 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D D G LH +C G E +LL+ HGA N D K TPLH AA+
Sbjct: 431 LLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADL---WKFTPLHEAAA 487
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K+L+ HGAD D +PL D +++LL A
Sbjct: 488 KGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTD--IQDLLRGDAA----------- 534
Query: 222 LHVAASLGS-ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
L AA G A KL + R G +T LHLAA + E A LL+HGA ++
Sbjct: 535 LLDAAKKGCLARVQKLCTPENINCRDTQGRN-STPLHLAAGYNNLEVAEYLLEHGADVNA 593
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
+ G PLH A +++ +L+ V A D TPLH A +G + LLL
Sbjct: 594 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQKG--RTQLCALLL 651
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVL 370
+ GADP + G TPL +A ++ A ++
Sbjct: 652 AHGADPTMKNQEGQTPLDLATADDIRALLI 681
Score = 93.9 bits (223), Expect = 2e-18
Identities = 96/335 (28%), Positives = 141/335 (42%), Gaps = 32/335 (9%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K G + LD G+T LH + L G + +LLL +G+ P+ T A+
Sbjct: 305 LHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT--------AA 356
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGA--CPDTPQVFTET 220
V+ +++ + D L + D E VK+L + C D + T
Sbjct: 357 QMGNEAVQQILSESTPIRTSDVDYRLLEASKAGDL-ETVKQLCSSQNVNCRDLEGRHS-T 414
Query: 221 PLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDW 280
PLH AA S + LL+ GADV A G LH A GH E A LL+ HGA ++
Sbjct: 415 PLHFAAGYNRVSVVEYLLHHGADVHAK-DKGGLVPLHNACSYGHYEVAELLVRHGASVNV 473
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL----------------HG 324
+ TPLH A E+ ++L+ AD K+ DG TPL
Sbjct: 474 ADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLVKEGDTDIQDLLRGDA 533
Query: 325 AIVRGARACDIARL-LLSAGADPNAADNFG--YTPLHIAALNEFSACVLLLLDYGGDVTL 381
A++ A+ +AR+ L + N D G TPLH+AA LL++G DV
Sbjct: 534 ALLDAAKKGCLARVQKLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNA 593
Query: 382 RTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSE 416
+ GG+ L I L K++ V+ ++
Sbjct: 594 QDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATD 628
Score = 91.1 bits (216), Expect = 1e-17
Identities = 90/291 (30%), Positives = 136/291 (46%), Gaps = 26/291 (8%)
Query: 119 TCLHLSCLVGS-----EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
T LH C V S ++ +LLL GA+ N + TPLH AA ++VL
Sbjct: 252 TALH--CAVASLHPKRKQVTELLLRKGANVN---EKNKDFMTPLHVAAERAHNDVMEVLH 306
Query: 174 AHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
HGA +NA ++ LH A L+ + + LL G+ P + T AA +G+ +
Sbjct: 307 KHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFT----AAQMGNEA 362
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ--TPLH 290
++L + +R + + L A++ G E + L +++ + G+ TPLH
Sbjct: 363 VQQIL-SESTPIRTSDVDYR---LLEASKAGDLETVKQLCS-SQNVNCRDLEGRHSTPLH 417
Query: 291 LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A + VVE L+ ADV AKD G PLH A G ++A LL+ GA N AD
Sbjct: 418 FAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHY--EVAELLVRHGASVNVAD 475
Query: 351 NFGYTPLH-IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
+ +TPLH AA ++ C LLL +G D T + G + L + D+
Sbjct: 476 LWKFTPLHEAAAKGKYEIC-KLLLKHGADPTKKNRDGNTPLDLVKEGDTDI 525
Score = 84.2 bits (199), Expect = 2e-15
Identities = 78/258 (30%), Positives = 115/258 (44%), Gaps = 13/258 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + +E + T LH++ + +++L HGA N D+ +T LH AA
Sbjct: 272 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTA---LHRAAL 328
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
A L ++L+++G+D S S + E V+++L T V + L
Sbjct: 329 AGHLQTCRLLLSYGSDP----SIISLQGFTAAQMGNEAVQQILSESTPIRTSDV--DYRL 382
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWP 281
A+ G K L ++ +V G+ +T LH AA LL HGA +
Sbjct: 383 LEASKAGDLETVKQLCSS-QNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGADVHAK 441
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+ G PLH A EV E+LV A V D TPLH A +G +I +LLL
Sbjct: 442 DKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKG--KYEICKLLLK 499
Query: 342 AGADPNAADNFGYTPLHI 359
GADP + G TPL +
Sbjct: 500 HGADPTKKNRDGNTPLDL 517
Score = 83.8 bits (198), Expect = 2e-15
Identities = 81/256 (31%), Positives = 111/256 (43%), Gaps = 20/256 (7%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G D D G LH +C G E +LLL HGA N D + TPLH AAS
Sbjct: 116 LLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDL---WQFTPLHEAAS 172
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPL 222
+ +L++HGAD L + ++ PE+ + L T + + L
Sbjct: 173 KNRVEVCSLLLSHGADPT--LVNCHGKSAVDMAPTPELRERL--------TYEFKGHSLL 222
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH---AECARLLLDHGAHID 279
A A K L A + TALH A H + LLL GA+++
Sbjct: 223 QAAREADLAKVKKTL--ALEIINFKQPQSHETALHCAVASLHPKRKQVTELLLRKGANVN 280
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
N TPLH+A +V+E+L A + A D G+T LH A + G RLL
Sbjct: 281 EKNKDFMTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAG--HLQTCRLL 338
Query: 340 LSAGADPNAADNFGYT 355
LS G+DP+ G+T
Sbjct: 339 LSYGSDPSIISLQGFT 354
Score = 83.4 bits (197), Expect = 3e-15
Identities = 89/295 (30%), Positives = 125/295 (42%), Gaps = 22/295 (7%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
L+ L + V+ D T LHL+ V+LLL HGA + D PLH
Sbjct: 79 LMALLTPLNVNCHASDGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKG---GLVPLH 135
Query: 159 CAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
A S ++L+ HGA VNA L +PLH A + EV LL GA P
Sbjct: 136 NACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKNRVEVCSLLLSHGADP------ 189
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
T H +++ A +L + + + L A E A+ + L +
Sbjct: 190 TLVNCHGKSAVDMAPTPELRERLTYEFKG------HSLLQAAREADLAKVKKTLALEIIN 243
Query: 278 IDWPNFRGQTPLHLATLA---QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACD 334
P +T LH A + + +V E+L+ + A+V K+ D TPLH A R D
Sbjct: 244 FKQPQSH-ETALHCAVASLHPKRKQVTELLLRKGANVNEKNKDFMTPLHVAAERAHN--D 300
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ +L GA NA D G T LH AAL LLL YG D ++ + G +A
Sbjct: 301 VMEVLHKHGAKMNALDTLGQTALHRAALAGHLQTCRLLLSYGSDPSIISLQGFTA 355
Score = 76.6 bits (180), Expect = 3e-13
Identities = 72/216 (33%), Positives = 96/216 (44%), Gaps = 18/216 (8%)
Query: 177 ADVNAGLS-DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
AD NA + + +PLH A + +V LL+ GA P+ ++ L +A A T
Sbjct: 1 ADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLADPSAKAVLT- 59
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAE-CARLLLDHGAHIDWPNFRGQTPLHLATL 294
G K L AA G+ E LL + + R TPLHLA
Sbjct: 60 -------------GEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGRKSTPLHLAAG 106
Query: 295 AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGY 354
+ +V++L+ ADV AKD G PLH A G ++ LLL GA NA D + +
Sbjct: 107 YNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHY--EVTELLLKHGACVNAMDLWQF 164
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
TPLH AA LLL +G D TL G SA+
Sbjct: 165 TPLHEAASKNRVEVCSLLLSHGADPTLVNCHGKSAV 200
Score = 72.5 bits (170), Expect = 5e-12
Identities = 72/224 (32%), Positives = 95/224 (42%), Gaps = 17/224 (7%)
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEV 200
A PN D+ TPLH AA + VL+ HGAD N +D + L A
Sbjct: 1 ADPNARDN---WNYTPLHEAAIKGKIDVCIVLLQHGADPNIRNTDGK----SALDLADPS 53
Query: 201 VKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAA 260
K +L T + + L A S LL + A+ G K+T LHLAA
Sbjct: 54 AKAVL-------TGEYKKDELLEAARSGNEEKLMALLTPLNVNCHASDGR-KSTPLHLAA 105
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
+LLL HGA + + G PLH A EV E+L+ A V A D T
Sbjct: 106 GYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFT 165
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
PLH A + ++ LLLS GADP + G + + +A E
Sbjct: 166 PLHEAASK--NRVEVCSLLLSHGADPTLVNCHGKSAVDMAPTPE 207
Score = 48.4 bits (110), Expect = 9e-05
Identities = 49/164 (29%), Positives = 73/164 (44%), Gaps = 11/164 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA-TPLHCAA 161
LL+ G D + D G LH + G + LL+ + NT ++T+ A TPLH AA
Sbjct: 584 LLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKY----NTCVNATDKWAFTPLHEAA 639
Query: 162 SAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT-PQVFTE 219
+L+AHGAD + ++PL A D ++ LL P+ P F
Sbjct: 640 QKGRTQLCALLLAHGADPTMKNQEGQTPLDLATADD----IRALLIDAMPPEALPTCFKP 695
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
V+ASL S + T L+A + + GP A+ A+ G
Sbjct: 696 QATVVSASLISPASTPSCLSAASSIDNLTGPLAELAVGGASNAG 739
>BC131801-1|AAI31802.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 107 bits (258), Expect = 1e-22
Identities = 74/221 (33%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
LK V PD ++ G T LH C+ EE VKLLL HGA+ N D+ T PLH AA+
Sbjct: 88 LKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWT---PLHAAATC 144
Query: 164 KSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE--TP 221
+ VK+L+ +GAD+ A SD + + Y + D P + +++E C + E
Sbjct: 145 GHINLVKILVQYGADLLAVNSDGN-MPYDLCEDEPTL--DVIET--CMAYQGITQEKINE 199
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+ VA + ++ AG D+ G AT LH+A +G+ A LLLDHG +D
Sbjct: 200 MRVAPEQQMIADIHCMIAAGQDLDWIDAQG-ATLLHIAGANGYLRAAELLLDHGVRVDVK 258
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
++ G PLH A +++ E+LV A + A+ + P+
Sbjct: 259 DWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPI 299
Score = 69.3 bits (162), Expect = 5e-11
Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 9/238 (3%)
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL 205
D E T LH VK+L++HGA+VNA ++ +PLH A +VK L+
Sbjct: 95 DLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILV 154
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ GA P + + + + + K + +A E
Sbjct: 155 QYGADLLAVNSDGNMPYDLCEDEPTLDVIETCM-----AYQGITQEKINEMRVAPEQQMI 209
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
++ G +DW + +G T LH+A L E+L+D V KD DG PLH A
Sbjct: 210 ADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAA 269
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G +A LL+S GA +A + P+ + EF +LL L + DV +++
Sbjct: 270 AFWG--QMQMAELLVSHGASLSARTSMDEMPIDLCEEEEFKV-LLLELKHKHDVIMKS 324
Score = 58.8 bits (136), Expect = 7e-08
Identities = 56/191 (29%), Positives = 82/191 (42%), Gaps = 7/191 (3%)
Query: 192 AVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPG 251
A L + E V+ L+ PD T LH KLLL+ GA+V A
Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNE- 133
Query: 252 KATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
T LH AA GH ++L+ +GA + N G P L +L+V+E +
Sbjct: 134 LWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGIT 193
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+ K + R ++ DI +++AG D + D G T LHIA N + L
Sbjct: 194 QEKINEMRVAPEQQMI-----ADI-HCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAEL 247
Query: 372 LLDYGGDVTLR 382
LLD+G V ++
Sbjct: 248 LLDHGVRVDVK 258
Score = 56.0 bits (129), Expect = 5e-07
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH + + E+VK LL GA + TPLH AA+ G + K+L+ GAD+ A
Sbjct: 105 LHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN 164
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G L ++ + + + + +A Q + + ++
Sbjct: 165 SDGNMP-YDLCEDEPTLDVIETCMAYQGITQ----EKINEMRVAPEQQMIADIHCMIAAG 219
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
D+ DA G T LH A G A LLL G + D G+ PLH AA
Sbjct: 220 QDLDWIDAQGATLLHIAGANGYLRA--AELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQM 277
Query: 369 VLLLLDYGGDVTLRTN 384
LL+ +G ++ RT+
Sbjct: 278 AELLVSHGASLSARTS 293
Score = 48.8 bits (111), Expect = 7e-05
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+F L A+L E V + + DG T LH + +I +LLLS
Sbjct: 65 SFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFE--EIVKLLLS 122
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
GA+ NA DN +TPLH AA V +L+ YG D+ + G
Sbjct: 123 HGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDG 167
Score = 46.8 bits (106), Expect = 3e-04
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT--WDSSTETKATPLHCA 160
++ G D D +D G T LH++ G +LLLDHG + WD PLH A
Sbjct: 215 MIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDG-----WEPLHAA 269
Query: 161 ASAKSLACVKVLIAHGADVNAGLS-DRSPL 189
A + ++L++HGA ++A S D P+
Sbjct: 270 AFWGQMQMAELLVSHGASLSARTSMDEMPI 299
Score = 46.0 bits (104), Expect = 5e-04
Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
+ AL A+ AE R L + D N G T LH + E+V++L+ A+V
Sbjct: 69 SVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVN 128
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
AKD + TPLH A G ++ ++L+ GAD A ++ G P
Sbjct: 129 AKDNELWTPLHAAATCG--HINLVKILVQYGADLLAVNSDGNMP 170
Score = 40.3 bits (90), Expect = 0.024
Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 9/190 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G + + D+ T LH + G VK+L+ +GA +S P
Sbjct: 120 LLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN---MPYDLCED 176
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+L ++ +A+ +++ R +++D + ++ AG D T
Sbjct: 177 EPTLDVIETCMAYQGITQEKINEMRVAPEQQMIAD----IHCMIAAGQDLDWIDAQGATL 232
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+A + G +LLL+ G V G LH AA G + A LL+ HGA +
Sbjct: 233 LHIAGANGYLRAAELLLDHGVRVDVKDWDG-WEPLHAAAFWGQMQMAELLVSHGASLSAR 291
Query: 282 NFRGQTPLHL 291
+ P+ L
Sbjct: 292 TSMDEMPIDL 301
>AL121889-1|CAI19080.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 107 bits (258), Expect = 1e-22
Identities = 74/221 (33%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
LK V PD ++ G T LH C+ EE VKLLL HGA+ N D+ T PLH AA+
Sbjct: 88 LKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWT---PLHAAATC 144
Query: 164 KSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE--TP 221
+ VK+L+ +GAD+ A SD + + Y + D P + +++E C + E
Sbjct: 145 GHINLVKILVQYGADLLAVNSDGN-MPYDLCEDEPTL--DVIET--CMAYQGITQEKINE 199
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+ VA + ++ AG D+ G AT LH+A +G+ A LLLDHG +D
Sbjct: 200 MRVAPEQQMIADIHCMIAAGQDLDWIDAQG-ATLLHIAGANGYLRAAELLLDHGVRVDVK 258
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
++ G PLH A +++ E+LV A + A+ + P+
Sbjct: 259 DWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPI 299
Score = 69.3 bits (162), Expect = 5e-11
Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 9/238 (3%)
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL 205
D E T LH VK+L++HGA+VNA ++ +PLH A +VK L+
Sbjct: 95 DLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILV 154
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ GA P + + + + + K + +A E
Sbjct: 155 QYGADLLAVNSDGNMPYDLCEDEPTLDVIETCM-----AYQGITQEKINEMRVAPEQQMI 209
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
++ G +DW + +G T LH+A L E+L+D V KD DG PLH A
Sbjct: 210 ADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAA 269
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G +A LL+S GA +A + P+ + EF +LL L + DV +++
Sbjct: 270 AFWG--QMQMAELLVSHGASLSARTSMDEMPIDLCEEEEFKV-LLLELKHKHDVIMKS 324
Score = 58.8 bits (136), Expect = 7e-08
Identities = 56/191 (29%), Positives = 82/191 (42%), Gaps = 7/191 (3%)
Query: 192 AVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPG 251
A L + E V+ L+ PD T LH KLLL+ GA+V A
Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNE- 133
Query: 252 KATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
T LH AA GH ++L+ +GA + N G P L +L+V+E +
Sbjct: 134 LWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGIT 193
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+ K + R ++ DI +++AG D + D G T LHIA N + L
Sbjct: 194 QEKINEMRVAPEQQMI-----ADI-HCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAEL 247
Query: 372 LLDYGGDVTLR 382
LLD+G V ++
Sbjct: 248 LLDHGVRVDVK 258
Score = 56.0 bits (129), Expect = 5e-07
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH + + E+VK LL GA + TPLH AA+ G + K+L+ GAD+ A
Sbjct: 105 LHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN 164
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G L ++ + + + + +A Q + + ++
Sbjct: 165 SDGNMP-YDLCEDEPTLDVIETCMAYQGITQ----EKINEMRVAPEQQMIADIHCMIAAG 219
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
D+ DA G T LH A G A LLL G + D G+ PLH AA
Sbjct: 220 QDLDWIDAQGATLLHIAGANGYLRA--AELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQM 277
Query: 369 VLLLLDYGGDVTLRTN 384
LL+ +G ++ RT+
Sbjct: 278 AELLVSHGASLSARTS 293
Score = 48.8 bits (111), Expect = 7e-05
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+F L A+L E V + + DG T LH + +I +LLLS
Sbjct: 65 SFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFE--EIVKLLLS 122
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
GA+ NA DN +TPLH AA V +L+ YG D+ + G
Sbjct: 123 HGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDG 167
Score = 46.8 bits (106), Expect = 3e-04
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT--WDSSTETKATPLHCA 160
++ G D D +D G T LH++ G +LLLDHG + WD PLH A
Sbjct: 215 MIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDG-----WEPLHAA 269
Query: 161 ASAKSLACVKVLIAHGADVNAGLS-DRSPL 189
A + ++L++HGA ++A S D P+
Sbjct: 270 AFWGQMQMAELLVSHGASLSARTSMDEMPI 299
Score = 46.0 bits (104), Expect = 5e-04
Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
+ AL A+ AE R L + D N G T LH + E+V++L+ A+V
Sbjct: 69 SVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVN 128
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
AKD + TPLH A G ++ ++L+ GAD A ++ G P
Sbjct: 129 AKDNELWTPLHAAATCG--HINLVKILVQYGADLLAVNSDGNMP 170
Score = 40.3 bits (90), Expect = 0.024
Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 9/190 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G + + D+ T LH + G VK+L+ +GA +S P
Sbjct: 120 LLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN---MPYDLCED 176
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+L ++ +A+ +++ R +++D + ++ AG D T
Sbjct: 177 EPTLDVIETCMAYQGITQEKINEMRVAPEQQMIAD----IHCMIAAGQDLDWIDAQGATL 232
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+A + G +LLL+ G V G LH AA G + A LL+ HGA +
Sbjct: 233 LHIAGANGYLRAAELLLDHGVRVDVKDWDG-WEPLHAAAFWGQMQMAELLVSHGASLSAR 291
Query: 282 NFRGQTPLHL 291
+ P+ L
Sbjct: 292 TSMDEMPIDL 301
>AL031657-1|CAI20058.1| 567|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16B protein.
Length = 567
Score = 107 bits (258), Expect = 1e-22
Identities = 74/221 (33%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
LK V PD ++ G T LH C+ EE VKLLL HGA+ N D+ T PLH AA+
Sbjct: 88 LKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWT---PLHAAATC 144
Query: 164 KSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE--TP 221
+ VK+L+ +GAD+ A SD + + Y + D P + +++E C + E
Sbjct: 145 GHINLVKILVQYGADLLAVNSDGN-MPYDLCEDEPTL--DVIET--CMAYQGITQEKINE 199
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+ VA + ++ AG D+ G AT LH+A +G+ A LLLDHG +D
Sbjct: 200 MRVAPEQQMIADIHCMIAAGQDLDWIDAQG-ATLLHIAGANGYLRAAELLLDHGVRVDVK 258
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
++ G PLH A +++ E+LV A + A+ + P+
Sbjct: 259 DWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPI 299
Score = 69.3 bits (162), Expect = 5e-11
Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 9/238 (3%)
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL 205
D E T LH VK+L++HGA+VNA ++ +PLH A +VK L+
Sbjct: 95 DLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILV 154
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ GA P + + + + + K + +A E
Sbjct: 155 QYGADLLAVNSDGNMPYDLCEDEPTLDVIETCM-----AYQGITQEKINEMRVAPEQQMI 209
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
++ G +DW + +G T LH+A L E+L+D V KD DG PLH A
Sbjct: 210 ADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAA 269
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G +A LL+S GA +A + P+ + EF +LL L + DV +++
Sbjct: 270 AFWG--QMQMAELLVSHGASLSARTSMDEMPIDLCEEEEFKV-LLLELKHKHDVIMKS 324
Score = 58.8 bits (136), Expect = 7e-08
Identities = 56/191 (29%), Positives = 82/191 (42%), Gaps = 7/191 (3%)
Query: 192 AVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPG 251
A L + E V+ L+ PD T LH KLLL+ GA+V A
Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNE- 133
Query: 252 KATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
T LH AA GH ++L+ +GA + N G P L +L+V+E +
Sbjct: 134 LWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGIT 193
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+ K + R ++ DI +++AG D + D G T LHIA N + L
Sbjct: 194 QEKINEMRVAPEQQMI-----ADI-HCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAEL 247
Query: 372 LLDYGGDVTLR 382
LLD+G V ++
Sbjct: 248 LLDHGVRVDVK 258
Score = 56.0 bits (129), Expect = 5e-07
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH + + E+VK LL GA + TPLH AA+ G + K+L+ GAD+ A
Sbjct: 105 LHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN 164
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G L ++ + + + + +A Q + + ++
Sbjct: 165 SDGNMP-YDLCEDEPTLDVIETCMAYQGITQ----EKINEMRVAPEQQMIADIHCMIAAG 219
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
D+ DA G T LH A G A LLL G + D G+ PLH AA
Sbjct: 220 QDLDWIDAQGATLLHIAGANGYLRA--AELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQM 277
Query: 369 VLLLLDYGGDVTLRTN 384
LL+ +G ++ RT+
Sbjct: 278 AELLVSHGASLSARTS 293
Score = 48.8 bits (111), Expect = 7e-05
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+F L A+L E V + + DG T LH + +I +LLLS
Sbjct: 65 SFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFE--EIVKLLLS 122
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
GA+ NA DN +TPLH AA V +L+ YG D+ + G
Sbjct: 123 HGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDG 167
Score = 46.8 bits (106), Expect = 3e-04
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT--WDSSTETKATPLHCA 160
++ G D D +D G T LH++ G +LLLDHG + WD PLH A
Sbjct: 215 MIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDG-----WEPLHAA 269
Query: 161 ASAKSLACVKVLIAHGADVNAGLS-DRSPL 189
A + ++L++HGA ++A S D P+
Sbjct: 270 AFWGQMQMAELLVSHGASLSARTSMDEMPI 299
Score = 46.0 bits (104), Expect = 5e-04
Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
+ AL A+ AE R L + D N G T LH + E+V++L+ A+V
Sbjct: 69 SVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVN 128
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
AKD + TPLH A G ++ ++L+ GAD A ++ G P
Sbjct: 129 AKDNELWTPLHAAATCG--HINLVKILVQYGADLLAVNSDGNMP 170
Score = 40.3 bits (90), Expect = 0.024
Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 9/190 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G + + D+ T LH + G VK+L+ +GA +S P
Sbjct: 120 LLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN---MPYDLCED 176
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+L ++ +A+ +++ R +++D + ++ AG D T
Sbjct: 177 EPTLDVIETCMAYQGITQEKINEMRVAPEQQMIAD----IHCMIAAGQDLDWIDAQGATL 232
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+A + G +LLL+ G V G LH AA G + A LL+ HGA +
Sbjct: 233 LHIAGANGYLRAAELLLDHGVRVDVKDWDG-WEPLHAAAFWGQMQMAELLVSHGASLSAR 291
Query: 282 NFRGQTPLHL 291
+ P+ L
Sbjct: 292 TSMDEMPIDL 301
>AF362910-1|AAK52796.1| 567|Homo sapiens CAAX box protein TIMAP
protein.
Length = 567
Score = 107 bits (258), Expect = 1e-22
Identities = 74/221 (33%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
LK V PD ++ G T LH C+ EE VKLLL HGA+ N D+ T PLH AA+
Sbjct: 88 LKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWT---PLHAAATC 144
Query: 164 KSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE--TP 221
+ VK+L+ +GAD+ A SD + + Y + D P + +++E C + E
Sbjct: 145 GHINLVKILVQYGADLLAVNSDGN-MPYDLCEDEPTL--DVIET--CMAYQGITQEKINE 199
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+ VA + ++ AG D+ G AT LH+A +G+ A LLLDHG +D
Sbjct: 200 MRVAPEQQMIADIHCMIAAGQDLDWIDAQG-ATLLHIAGANGYLRAAELLLDHGVRVDVK 258
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
++ G PLH A +++ E+LV A + A+ + P+
Sbjct: 259 DWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPI 299
Score = 69.3 bits (162), Expect = 5e-11
Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 9/238 (3%)
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL 205
D E T LH VK+L++HGA+VNA ++ +PLH A +VK L+
Sbjct: 95 DLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILV 154
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ GA P + + + + + K + +A E
Sbjct: 155 QYGADLLAVNSDGNMPYDLCEDEPTLDVIETCM-----AYQGITQEKINEMRVAPEQQMI 209
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
++ G +DW + +G T LH+A L E+L+D V KD DG PLH A
Sbjct: 210 ADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAA 269
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G +A LL+S GA +A + P+ + EF +LL L + DV +++
Sbjct: 270 AFWG--QMQMAELLVSHGASLSARTSMDEMPIDLCEEEEFKV-LLLELKHKHDVIMKS 324
Score = 58.8 bits (136), Expect = 7e-08
Identities = 56/191 (29%), Positives = 82/191 (42%), Gaps = 7/191 (3%)
Query: 192 AVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPG 251
A L + E V+ L+ PD T LH KLLL+ GA+V A
Sbjct: 75 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNE- 133
Query: 252 KATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
T LH AA GH ++L+ +GA + N G P L +L+V+E +
Sbjct: 134 LWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGIT 193
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+ K + R ++ DI +++AG D + D G T LHIA N + L
Sbjct: 194 QEKINEMRVAPEQQMI-----ADI-HCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAEL 247
Query: 372 LLDYGGDVTLR 382
LLD+G V ++
Sbjct: 248 LLDHGVRVDVK 258
Score = 56.0 bits (129), Expect = 5e-07
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH + + E+VK LL GA + TPLH AA+ G + K+L+ GAD+ A
Sbjct: 105 LHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN 164
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G L ++ + + + + +A Q + + ++
Sbjct: 165 SDGNMP-YDLCEDEPTLDVIETCMAYQGITQ----EKINEMRVAPEQQMIADIHCMIAAG 219
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
D+ DA G T LH A G A LLL G + D G+ PLH AA
Sbjct: 220 QDLDWIDAQGATLLHIAGANGYLRA--AELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQM 277
Query: 369 VLLLLDYGGDVTLRTN 384
LL+ +G ++ RT+
Sbjct: 278 AELLVSHGASLSARTS 293
Score = 48.8 bits (111), Expect = 7e-05
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+F L A+L E V + + DG T LH + +I +LLLS
Sbjct: 65 SFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFE--EIVKLLLS 122
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
GA+ NA DN +TPLH AA V +L+ YG D+ + G
Sbjct: 123 HGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDG 167
Score = 46.8 bits (106), Expect = 3e-04
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT--WDSSTETKATPLHCA 160
++ G D D +D G T LH++ G +LLLDHG + WD PLH A
Sbjct: 215 MIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDG-----WEPLHAA 269
Query: 161 ASAKSLACVKVLIAHGADVNAGLS-DRSPL 189
A + ++L++HGA ++A S D P+
Sbjct: 270 AFWGQMQMAELLVSHGASLSARTSMDEMPI 299
Score = 46.0 bits (104), Expect = 5e-04
Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
+ AL A+ AE R L + D N G T LH + E+V++L+ A+V
Sbjct: 69 SVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVN 128
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
AKD + TPLH A G ++ ++L+ GAD A ++ G P
Sbjct: 129 AKDNELWTPLHAAATCG--HINLVKILVQYGADLLAVNSDGNMP 170
Score = 40.3 bits (90), Expect = 0.024
Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 9/190 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G + + D+ T LH + G VK+L+ +GA +S P
Sbjct: 120 LLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN---MPYDLCED 176
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+L ++ +A+ +++ R +++D + ++ AG D T
Sbjct: 177 EPTLDVIETCMAYQGITQEKINEMRVAPEQQMIAD----IHCMIAAGQDLDWIDAQGATL 232
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+A + G +LLL+ G V G LH AA G + A LL+ HGA +
Sbjct: 233 LHIAGANGYLRAAELLLDHGVRVDVKDWDG-WEPLHAAAFWGQMQMAELLVSHGASLSAR 291
Query: 282 NFRGQTPLHL 291
+ P+ L
Sbjct: 292 TSMDEMPIDL 301
>AB020630-1|BAA74846.2| 578|Homo sapiens KIAA0823 protein protein.
Length = 578
Score = 107 bits (258), Expect = 1e-22
Identities = 74/221 (33%), Positives = 112/221 (50%), Gaps = 11/221 (4%)
Query: 104 LKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASA 163
LK V PD ++ G T LH C+ EE VKLLL HGA+ N D+ T PLH AA+
Sbjct: 99 LKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWT---PLHAAATC 155
Query: 164 KSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE--TP 221
+ VK+L+ +GAD+ A SD + + Y + D P + +++E C + E
Sbjct: 156 GHINLVKILVQYGADLLAVNSDGN-MPYDLCEDEPTL--DVIET--CMAYQGITQEKINE 210
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
+ VA + ++ AG D+ G AT LH+A +G+ A LLLDHG +D
Sbjct: 211 MRVAPEQQMIADIHCMIAAGQDLDWIDAQG-ATLLHIAGANGYLRAAELLLDHGVRVDVK 269
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
++ G PLH A +++ E+LV A + A+ + P+
Sbjct: 270 DWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPI 310
Score = 69.3 bits (162), Expect = 5e-11
Identities = 64/238 (26%), Positives = 100/238 (42%), Gaps = 9/238 (3%)
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL 205
D E T LH VK+L++HGA+VNA ++ +PLH A +VK L+
Sbjct: 106 DLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILV 165
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ GA P + + + + + K + +A E
Sbjct: 166 QYGADLLAVNSDGNMPYDLCEDEPTLDVIETCM-----AYQGITQEKINEMRVAPEQQMI 220
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
++ G +DW + +G T LH+A L E+L+D V KD DG PLH A
Sbjct: 221 ADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAA 280
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
G +A LL+S GA +A + P+ + EF +LL L + DV +++
Sbjct: 281 AFWG--QMQMAELLVSHGASLSARTSMDEMPIDLCEEEEFKV-LLLELKHKHDVIMKS 335
Score = 58.8 bits (136), Expect = 7e-08
Identities = 56/191 (29%), Positives = 82/191 (42%), Gaps = 7/191 (3%)
Query: 192 AVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPG 251
A L + E V+ L+ PD T LH KLLL+ GA+V A
Sbjct: 86 ASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNE- 144
Query: 252 KATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
T LH AA GH ++L+ +GA + N G P L +L+V+E +
Sbjct: 145 LWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGIT 204
Query: 312 RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+ K + R ++ DI +++AG D + D G T LHIA N + L
Sbjct: 205 QEKINEMRVAPEQQMI-----ADI-HCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAEL 258
Query: 372 LLDYGGDVTLR 382
LLD+G V ++
Sbjct: 259 LLDHGVRVDVK 269
Score = 56.0 bits (129), Expect = 5e-07
Identities = 52/196 (26%), Positives = 80/196 (40%), Gaps = 7/196 (3%)
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH + + E+VK LL GA + TPLH AA+ G + K+L+ GAD+ A
Sbjct: 116 LHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVN 175
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G L ++ + + + + +A Q + + ++
Sbjct: 176 SDGNMP-YDLCEDEPTLDVIETCMAYQGITQ----EKINEMRVAPEQQMIADIHCMIAAG 230
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
D+ DA G T LH A G A LLL G + D G+ PLH AA
Sbjct: 231 QDLDWIDAQGATLLHIAGANGYLRA--AELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQM 288
Query: 369 VLLLLDYGGDVTLRTN 384
LL+ +G ++ RT+
Sbjct: 289 AELLVSHGASLSARTS 304
Score = 48.8 bits (111), Expect = 7e-05
Identities = 34/105 (32%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
+F L A+L E V + + DG T LH + +I +LLLS
Sbjct: 76 SFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFE--EIVKLLLS 133
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
GA+ NA DN +TPLH AA V +L+ YG D+ + G
Sbjct: 134 HGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDG 178
Score = 46.8 bits (106), Expect = 3e-04
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 8/90 (8%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT--WDSSTETKATPLHCA 160
++ G D D +D G T LH++ G +LLLDHG + WD PLH A
Sbjct: 226 MIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDG-----WEPLHAA 280
Query: 161 ASAKSLACVKVLIAHGADVNAGLS-DRSPL 189
A + ++L++HGA ++A S D P+
Sbjct: 281 AFWGQMQMAELLVSHGASLSARTSMDEMPI 310
Score = 46.0 bits (104), Expect = 5e-04
Identities = 34/104 (32%), Positives = 51/104 (49%), Gaps = 2/104 (1%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
+ AL A+ AE R L + D N G T LH + E+V++L+ A+V
Sbjct: 80 SVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVN 139
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
AKD + TPLH A G ++ ++L+ GAD A ++ G P
Sbjct: 140 AKDNELWTPLHAAATCG--HINLVKILVQYGADLLAVNSDGNMP 181
Score = 40.3 bits (90), Expect = 0.024
Identities = 46/190 (24%), Positives = 77/190 (40%), Gaps = 9/190 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G + + D+ T LH + G VK+L+ +GA +S P
Sbjct: 131 LLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGN---MPYDLCED 187
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+L ++ +A+ +++ R +++D + ++ AG D T
Sbjct: 188 EPTLDVIETCMAYQGITQEKINEMRVAPEQQMIAD----IHCMIAAGQDLDWIDAQGATL 243
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+A + G +LLL+ G V G LH AA G + A LL+ HGA +
Sbjct: 244 LHIAGANGYLRAAELLLDHGVRVDVKDWDG-WEPLHAAAFWGQMQMAELLVSHGASLSAR 302
Query: 282 NFRGQTPLHL 291
+ P+ L
Sbjct: 303 TSMDEMPIDL 312
>BC065710-1|AAH65710.1| 329|Homo sapiens ankyrin repeat and SOCS
box-containing 5 protein.
Length = 329
Score = 107 bits (257), Expect = 1e-22
Identities = 78/218 (35%), Positives = 110/218 (50%), Gaps = 6/218 (2%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+PLH AAS L ++ L++ G +VNA D +PLH A L D + LLEAGA +
Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPL A S GS SC +LLL GA +A + + H AA GH EC +L+
Sbjct: 132 ITIDGVTPLFNACSQGSPSCAELLLEYGA--KAQLESCLPSPTHEAASKGHHECLDILIS 189
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
G +D TPL++A ++Q + L+ ADV+ K TPLH A + +
Sbjct: 190 WGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ-KGKYWDTPLHAAAQQS--ST 246
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+I LLL GAD NA + P+ +A + +LL
Sbjct: 247 EIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILL 284
Score = 85.0 bits (201), Expect = 9e-16
Identities = 75/243 (30%), Positives = 107/243 (44%), Gaps = 11/243 (4%)
Query: 63 IGNGNYDETIQFASE------AEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
I GN E + A+E +G + R+ + A G+ + L LL G + + +
Sbjct: 43 IVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLD 102
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
T LH +CL C + LL+ GA+ N + T TPL A S S +C ++L+ +G
Sbjct: 103 HVTPLHEACLGDHVACARTLLEAGANVN---AITIDGVTPLFNACSQGSPSCAELLLEYG 159
Query: 177 ADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
A SP H A E + L+ G D TPL+VA C
Sbjct: 160 AKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWK 219
Query: 237 LLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQ 296
LL AGADV+ G T LH AA+ E LLL+ GA I+ N P+ +AT +
Sbjct: 220 LLYAGADVQ--KGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSS 277
Query: 297 SLE 299
+E
Sbjct: 278 MVE 280
Score = 80.2 bits (189), Expect = 2e-14
Identities = 66/199 (33%), Positives = 92/199 (46%), Gaps = 5/199 (2%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
+DRSPLH A ++ LL G + + TPLH A +C + LL AGA+
Sbjct: 69 ADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGAN 128
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V A G T L A G CA LLL++GA + +P H A E +++
Sbjct: 129 VNAITIDG-VTPLFNACSQGSPSCAELLLEYGAKAQLESCL-PSPTHEAASKGHHECLDI 186
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ DV + TPL+ A + C I +LL AGAD + TPLH AA
Sbjct: 187 LISWGIDVDQEIPHLGTPLYVACMSQQFHC-IWKLLY-AGADVQKG-KYWDTPLHAAAQQ 243
Query: 364 EFSACVLLLLDYGGDVTLR 382
+ V LLL++G D+ +
Sbjct: 244 SSTEIVNLLLEFGADINAK 262
Score = 55.2 bits (127), Expect = 8e-07
Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Query: 266 ECARLLLD-HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
E AR+ + +G ++ ++PLH A L + L+ + +V A D TPLH
Sbjct: 50 EAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHE 109
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A + AC AR LL AGA+ NA G TPL A +C LLL+YG L +
Sbjct: 110 ACLGDHVAC--ARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLES 166
Score = 44.0 bits (99), Expect = 0.002
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
R+PLH A +G R LLS G + NA TPLH A L + AC LL+ G +
Sbjct: 71 RSPLHEAASQGRLLA--LRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGAN 128
Query: 379 VTLRTNGGVSAL 390
V T GV+ L
Sbjct: 129 VNAITIDGVTPL 140
>AY057053-1|AAL18248.1| 329|Homo sapiens SOCS box protein ASB-5
protein.
Length = 329
Score = 107 bits (257), Expect = 1e-22
Identities = 78/218 (35%), Positives = 110/218 (50%), Gaps = 6/218 (2%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+PLH AAS L ++ L++ G +VNA D +PLH A L D + LLEAGA +
Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPL A S GS SC +LLL GA +A + + H AA GH EC +L+
Sbjct: 132 ITIDGVTPLFNACSQGSPSCAELLLEYGA--KAQLESCLPSPTHEAASKGHHECLDILIS 189
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
G +D TPL++A ++Q + L+ ADV+ K TPLH A + +
Sbjct: 190 WGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ-KGKYWDTPLHAAAQQS--ST 246
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+I LLL GAD NA + P+ +A + +LL
Sbjct: 247 EIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILL 284
Score = 85.0 bits (201), Expect = 9e-16
Identities = 75/243 (30%), Positives = 107/243 (44%), Gaps = 11/243 (4%)
Query: 63 IGNGNYDETIQFASE------AEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
I GN E + A+E +G + R+ + A G+ + L LL G + + +
Sbjct: 43 IVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLD 102
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
T LH +CL C + LL+ GA+ N + T TPL A S S +C ++L+ +G
Sbjct: 103 HVTPLHEACLGDHVACARTLLEAGANVN---AITIDGVTPLFNACSQGSPSCAELLLEYG 159
Query: 177 ADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
A SP H A E + L+ G D TPL+VA C
Sbjct: 160 AKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWK 219
Query: 237 LLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQ 296
LL AGADV+ G T LH AA+ E LLL+ GA I+ N P+ +AT +
Sbjct: 220 LLYAGADVQ--KGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSS 277
Query: 297 SLE 299
+E
Sbjct: 278 MVE 280
Score = 80.2 bits (189), Expect = 2e-14
Identities = 66/199 (33%), Positives = 92/199 (46%), Gaps = 5/199 (2%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
+DRSPLH A ++ LL G + + TPLH A +C + LL AGA+
Sbjct: 69 ADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGAN 128
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V A G T L A G CA LLL++GA + +P H A E +++
Sbjct: 129 VNAITIDG-VTPLFNACSQGSPSCAELLLEYGAKAQLESCL-PSPTHEAASKGHHECLDI 186
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ DV + TPL+ A + C I +LL AGAD + TPLH AA
Sbjct: 187 LISWGIDVDQEIPHLGTPLYVACMSQQFHC-IWKLLY-AGADVQKG-KYWDTPLHAAAQQ 243
Query: 364 EFSACVLLLLDYGGDVTLR 382
+ V LLL++G D+ +
Sbjct: 244 SSTEIVNLLLEFGADINAK 262
Score = 55.2 bits (127), Expect = 8e-07
Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Query: 266 ECARLLLD-HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
E AR+ + +G ++ ++PLH A L + L+ + +V A D TPLH
Sbjct: 50 EAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHE 109
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A + AC AR LL AGA+ NA G TPL A +C LLL+YG L +
Sbjct: 110 ACLGDHVAC--ARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLES 166
Score = 44.0 bits (99), Expect = 0.002
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
R+PLH A +G R LLS G + NA TPLH A L + AC LL+ G +
Sbjct: 71 RSPLHEAASQGRLLA--LRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGAN 128
Query: 379 VTLRTNGGVSAL 390
V T GV+ L
Sbjct: 129 VNAITIDGVTPL 140
>AK098693-1|BAC05382.1| 276|Homo sapiens protein ( Homo sapiens
cDNA FLJ25827 fis, clone TST08047. ).
Length = 276
Score = 107 bits (257), Expect = 1e-22
Identities = 78/218 (35%), Positives = 110/218 (50%), Gaps = 6/218 (2%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+PLH AAS L ++ L++ G +VNA D +PLH A L D + LLEAGA +
Sbjct: 19 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 78
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPL A S GS SC +LLL GA +A + + H AA GH EC +L+
Sbjct: 79 ITIDGVTPLFNACSQGSPSCAELLLEYGA--KAQLESCLPSPTHEAASKGHHECLDILIS 136
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
G +D TPL++A ++Q + L+ ADV+ K TPLH A + +
Sbjct: 137 WGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ-KGKYWDTPLHAAAQQS--ST 193
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+I LLL GAD NA + P+ +A + +LL
Sbjct: 194 EIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILL 231
Score = 82.6 bits (195), Expect = 5e-15
Identities = 69/220 (31%), Positives = 98/220 (44%), Gaps = 5/220 (2%)
Query: 80 GGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDH 139
G + R+ + A G+ + L LL G + + + T LH +CL C + LL+
Sbjct: 13 GSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEA 72
Query: 140 GAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPE 199
GA+ N + T TPL A S S +C ++L+ +GA SP H A E
Sbjct: 73 GANVN---AITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLESCLPSPTHEAASKGHHE 129
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
+ L+ G D TPL+VA C LL AGADV+ G T LH A
Sbjct: 130 CLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ--KGKYWDTPLHAA 187
Query: 260 AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLE 299
A+ E LLL+ GA I+ N P+ +AT + +E
Sbjct: 188 AQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSSMVE 227
Score = 81.0 bits (191), Expect = 1e-14
Identities = 67/204 (32%), Positives = 93/204 (45%), Gaps = 5/204 (2%)
Query: 179 VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLL 238
V +DRSPLH A ++ LL G + + TPLH A +C + LL
Sbjct: 11 VTGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLL 70
Query: 239 NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSL 298
AGA+V A G T L A G CA LLL++GA + +P H A
Sbjct: 71 EAGANVNAITIDG-VTPLFNACSQGSPSCAELLLEYGAKAQLESCL-PSPTHEAASKGHH 128
Query: 299 EVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
E +++L+ DV + TPL+ A + C I +LL AGAD + TPLH
Sbjct: 129 ECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHC-IWKLLY-AGADVQKG-KYWDTPLH 185
Query: 359 IAALNEFSACVLLLLDYGGDVTLR 382
AA + V LLL++G D+ +
Sbjct: 186 AAAQQSSTEIVNLLLEFGADINAK 209
Score = 69.7 bits (163), Expect = 3e-11
Identities = 56/175 (32%), Positives = 82/175 (46%), Gaps = 9/175 (5%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL+ G + + + G T L +C GS C +LLL++GA +P H AAS
Sbjct: 69 LLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQL----ESCLPSPTHEAAS 124
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
C+ +LI+ G DV+ + +PL+ A +S + +LL AGA + + +TP
Sbjct: 125 KGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGK-YWDTP 183
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGA 276
LH AA S LLL GAD+ A + +A E R+LL H A
Sbjct: 184 LHAAAQQSSTEIVNLLLEFGADIN-AKNTELLRPIDVATSSSMVE--RILLQHEA 235
Score = 54.0 bits (124), Expect = 2e-06
Identities = 37/98 (37%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 286 QTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGAD 345
++PLH A L + L+ + +V A D TPLH A + AC AR LL AGA+
Sbjct: 18 RSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVAC--ARTLLEAGAN 75
Query: 346 PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
NA G TPL A +C LLL+YG L +
Sbjct: 76 VNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLES 113
Score = 44.0 bits (99), Expect = 0.002
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
R+PLH A +G R LLS G + NA TPLH A L + AC LL+ G +
Sbjct: 18 RSPLHEAASQGRLLA--LRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGAN 75
Query: 379 VTLRTNGGVSAL 390
V T GV+ L
Sbjct: 76 VNAITIDGVTPL 87
>AK096441-1|BAC04791.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ39122 fis, clone NTONG2006783, weakly similar to
ANKYRIN 1. ).
Length = 329
Score = 107 bits (257), Expect = 1e-22
Identities = 78/218 (35%), Positives = 110/218 (50%), Gaps = 6/218 (2%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+PLH AAS L ++ L++ G +VNA D +PLH A L D + LLEAGA +
Sbjct: 72 SPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGANVNA 131
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
+ TPL A S GS SC +LLL GA +A + + H AA GH EC +L+
Sbjct: 132 ITIDGVTPLFNACSQGSPSCAELLLEYGA--KAQLESCLPSPTHEAASKGHHECLDILIS 189
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
G +D TPL++A ++Q + L+ ADV+ K TPLH A + +
Sbjct: 190 WGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAGADVQ-KGKYWDTPLHAAAQQS--ST 246
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLL 371
+I LLL GAD NA + P+ +A + +LL
Sbjct: 247 EIVNLLLEFGADINAKNTELLRPIDVATSSSMVERILL 284
Score = 85.0 bits (201), Expect = 9e-16
Identities = 75/243 (30%), Positives = 107/243 (44%), Gaps = 11/243 (4%)
Query: 63 IGNGNYDETIQFASE------AEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDA 116
I GN E + A+E +G + R+ + A G+ + L LL G + + +
Sbjct: 43 IVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLD 102
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
T LH +CL C + LL+ GA+ N + T TPL A S S +C ++L+ +G
Sbjct: 103 HVTPLHEACLGDHVACARTLLEAGANVN---AITIDGVTPLFNACSQGSPSCAELLLEYG 159
Query: 177 ADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKL 236
A SP H A E + L+ G D TPL+VA C
Sbjct: 160 AKAQLESCLPSPTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWK 219
Query: 237 LLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQ 296
LL AGADV+ G T LH AA+ E LLL+ GA I+ N P+ +AT +
Sbjct: 220 LLYAGADVQ--KGKYWDTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATSSS 277
Query: 297 SLE 299
+E
Sbjct: 278 MVE 280
Score = 80.2 bits (189), Expect = 2e-14
Identities = 66/199 (33%), Positives = 92/199 (46%), Gaps = 5/199 (2%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
+DRSPLH A ++ LL G + + TPLH A +C + LL AGA+
Sbjct: 69 ADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGAN 128
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V A G T L A G CA LLL++GA + +P H A E +++
Sbjct: 129 VNAITIDG-VTPLFNACSQGSPSCAELLLEYGAKAQLESCL-PSPTHEAASKGHHECLDI 186
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ DV + TPL+ A + C I +LL AGAD + TPLH AA
Sbjct: 187 LISWGIDVDQEIPHLGTPLYVACMSQQFHC-IWKLLY-AGADVQKG-KYWDTPLHAAAQQ 243
Query: 364 EFSACVLLLLDYGGDVTLR 382
+ V LLL++G D+ +
Sbjct: 244 SSTEIVNLLLEFGADINAK 262
Score = 55.2 bits (127), Expect = 8e-07
Identities = 41/119 (34%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Query: 266 ECARLLLD-HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHG 324
E AR+ + +G ++ ++PLH A L + L+ + +V A D TPLH
Sbjct: 50 EAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHE 109
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
A + AC AR LL AGA+ NA G TPL A +C LLL+YG L +
Sbjct: 110 ACLGDHVAC--ARTLLEAGANVNAITIDGVTPLFNACSQGSPSCAELLLEYGAKAQLES 166
Score = 44.0 bits (99), Expect = 0.002
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
R+PLH A +G R LLS G + NA TPLH A L + AC LL+ G +
Sbjct: 71 RSPLHEAASQGRLLA--LRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAGAN 128
Query: 379 VTLRTNGGVSAL 390
V T GV+ L
Sbjct: 129 VNAITIDGVTPL 140
>BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein.
Length = 1030
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 541 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 599
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 600 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 657
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 658 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 715
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 716 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 775
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 776 GDTALHVALQR 786
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 517 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 574
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 575 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 633
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 634 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 692
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 693 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 751
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 752 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 800
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 488 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 542
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 543 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 602
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 603 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 661
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 662 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 721
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 722 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 779
Query: 390 LSFIVRR 396
L ++R
Sbjct: 780 LHVALQR 786
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 666 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 723
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 724 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 783
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 784 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 840
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 841 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 896
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 897 GAAPGPEAAECLVCSELALLVL--FSPC 922
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 505 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 560
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 561 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 620
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 621 VVRALCE 627
>AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 919
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 430 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 488
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 489 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 546
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 547 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 604
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 605 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 664
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 665 GDTALHVALQR 675
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 406 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 463
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 464 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 522
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 523 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 581
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 582 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 640
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 641 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 689
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 377 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 431
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 432 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 491
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 492 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 550
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 551 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 610
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 611 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 668
Query: 390 LSFIVRR 396
L ++R
Sbjct: 669 LHVALQR 675
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 555 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 612
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 613 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 672
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 673 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 729
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 730 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 785
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 786 GAAPGPEAAECLVCSELALLVL--FSPC 811
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 394 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 449
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 450 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 509
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 510 VVRALCE 516
>AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 753
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 401 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 459
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 460 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 517
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 518 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 575
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 576 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 635
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 636 GDTALHVALQR 646
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 377 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 434
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 435 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 493
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 494 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 552
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 553 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 611
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 612 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 660
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 348 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 402
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 403 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 462
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 463 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 521
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 522 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 581
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 582 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 639
Query: 390 LSFIVRR 396
L ++R
Sbjct: 640 LHVALQR 646
Score = 63.3 bits (147), Expect = 3e-09
Identities = 73/267 (27%), Positives = 112/267 (41%), Gaps = 13/267 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D ++ T LH++ G E V+ L + G N D+ ++T PLH A S
Sbjct: 452 LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDT---PLHSAIS 508
Query: 163 AKSLAC--VKVLI-AHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL-EAGACPDTPQVF 217
A + A V+VL DV A S + LH+A L V+++L A D +
Sbjct: 509 AGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKED 568
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
T LH+AA ++L+ G + LHLA + H LL+D G
Sbjct: 569 GFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCS 628
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA-DVRAKDADGRTPLHG--AIVRGARACD 334
++ + G T LH+A Q +++ ++ D D R G
Sbjct: 629 VNAEDEEGDTALHVAL--QRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAA 686
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAA 361
+A L GAD + ++ G +PL +AA
Sbjct: 687 VACFLALEGADVSYTNHRGRSPLDLAA 713
Score = 53.6 bits (123), Expect = 2e-06
Identities = 65/217 (29%), Positives = 96/217 (44%), Gaps = 13/217 (5%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 526 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 583
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 584 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 643
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 644 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 700
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
N RG++PL LA + L+ ++ R VRA+D +
Sbjct: 701 TNHRGRSPLDLAAEGRVLKALQGCAQRFR-VRAQDEE 736
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 365 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 420
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 421 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 480
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 481 VVRALCE 487
>AL691432-2|CAM12831.1| 999|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 999
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 510 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 568
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 569 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 626
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 627 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 684
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 685 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 744
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 745 GDTALHVALQR 755
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 486 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 543
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 544 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 602
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 603 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 661
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 662 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 720
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 721 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 769
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 457 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 511
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 512 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 571
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 572 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 630
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 631 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 690
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 691 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 748
Query: 390 LSFIVRR 396
L ++R
Sbjct: 749 LHVALQR 755
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 635 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 692
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 693 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 752
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 753 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 809
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 810 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 865
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 866 GAAPGPEAAECLVCSELALLVL--FSPC 891
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 474 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 529
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 530 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 589
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 590 VVRALCE 596
>AL691432-1|CAM12830.1| 948|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 948
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 459 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 517
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 518 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 575
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 576 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 633
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 634 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 693
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 694 GDTALHVALQR 704
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 435 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 492
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 493 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 551
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 552 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 610
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 611 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 669
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 670 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 718
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 406 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 460
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 461 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 520
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 521 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 579
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 580 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 639
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 640 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 697
Query: 390 LSFIVRR 396
L ++R
Sbjct: 698 LHVALQR 704
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 584 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 641
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 642 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 701
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 702 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 758
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 759 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 814
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 815 GAAPGPEAAECLVCSELALLVL--FSPC 840
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 423 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 478
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 479 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 538
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 539 VVRALCE 545
>AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens
cDNA FLJ25919 fis, clone CBR04994. ).
Length = 802
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 466 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 524
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 525 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 582
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 583 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 640
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 641 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 700
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 701 GDTALHVALQR 711
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 442 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 499
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 500 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 558
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 559 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 617
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 618 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 676
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 677 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 725
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 413 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 467
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 468 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 527
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 528 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 586
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 587 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 646
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 647 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 704
Query: 390 LSFIVRR 396
L ++R
Sbjct: 705 LHVALQR 711
Score = 63.3 bits (147), Expect = 3e-09
Identities = 73/267 (27%), Positives = 112/267 (41%), Gaps = 13/267 (4%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D ++ T LH++ G E V+ L + G N D+ ++T PLH A S
Sbjct: 517 LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDT---PLHSAIS 573
Query: 163 AKSLAC--VKVLI-AHGADVNAGLSDR-SPLHYAVLSDAPEVVKELL-EAGACPDTPQVF 217
A + A V+VL DV A S + LH+A L V+++L A D +
Sbjct: 574 AGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKED 633
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
T LH+AA ++L+ G + LHLA + H LL+D G
Sbjct: 634 GFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCS 693
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA-DVRAKDADGRTPLHG--AIVRGARACD 334
++ + G T LH+A Q +++ ++ D D R G
Sbjct: 694 VNAEDEEGDTALHVAL--QRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAA 751
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAA 361
+A L GAD + ++ G +PL +AA
Sbjct: 752 VACFLALEGADVSYTNHRGRSPLDLAA 778
Score = 51.2 bits (117), Expect = 1e-05
Identities = 62/213 (29%), Positives = 93/213 (43%), Gaps = 12/213 (5%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 591 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 648
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 649 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 708
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 709 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 765
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
N RG++PL LA + L+ ++ R + +A
Sbjct: 766 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA 798
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 430 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 485
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 486 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 545
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 546 VVRALCE 552
>AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens
cDNA FLJ25613 fis, clone STM01546. ).
Length = 353
Score = 107 bits (256), Expect = 2e-22
Identities = 90/250 (36%), Positives = 118/250 (47%), Gaps = 8/250 (3%)
Query: 97 SILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATP 156
SI + + G + + D LH + +E+ + LLL H A N D +T P
Sbjct: 72 SIKIGNYIPTGANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQT---P 128
Query: 157 LHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
LH AA+ ++ C + L + +N A S RS LH+AV S E V LL GA +
Sbjct: 129 LHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVCD 188
Query: 216 VFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
PLH AA LG KLL+ GAD+ G LH AA G E + LL G
Sbjct: 189 KKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGL-LHTAAASGQIEVVKYLLRMG 247
Query: 276 AHIDWPNFRGQTPLHLAT-LAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACD 334
A ID PN G T LH+A L Q +E LV+ A+V + G TPLH A V A
Sbjct: 248 AEIDEPNAFGNTALHIACYLGQDAVAIE-LVNAGANVNQPNDKGFTPLHVAAVSTNGALC 306
Query: 335 IARLLLSAGA 344
+ LL++ GA
Sbjct: 307 L-ELLVNNGA 315
Score = 104 bits (250), Expect = 1e-21
Identities = 75/223 (33%), Positives = 117/223 (52%), Gaps = 5/223 (2%)
Query: 156 PLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTP 214
PLH AA++++ + +L+AH ADVNA ++PLH A + A + + L + +
Sbjct: 95 PLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPLLSSLNVA 154
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH 274
+ LH A G LLLN GA + + LH AA GH E +LL+
Sbjct: 155 DRSGRSALHHAVHSGHLETVNLLLNKGASLNVC-DKKERQPLHWAAFLGHLEVLKLLVAR 213
Query: 275 GAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACD 334
GA + + +G LH A + +EVV+ L+ A++ +A G T LH A G A
Sbjct: 214 GADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQDA-- 271
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAALNEFSA-CVLLLLDYG 376
+A L++AGA+ N ++ G+TPLH+AA++ A C+ LL++ G
Sbjct: 272 VAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNG 314
Score = 100 bits (240), Expect = 2e-20
Identities = 74/219 (33%), Positives = 109/219 (49%), Gaps = 4/219 (1%)
Query: 173 IAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
I GA+VNA +PLH A S +V+ LL A + +TPLHVAA+ +
Sbjct: 79 IPTGANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRAT 138
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
C + L + + A G++ ALH A GH E LLL+ GA ++ + + + PLH
Sbjct: 139 KCAEALAPLLSSLNVADRSGRS-ALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHW 197
Query: 292 ATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADN 351
A LEV+++LV R AD+ KD G LH A G ++ + LL GA+ + +
Sbjct: 198 AAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASG--QIEVVKYLLRMGAEIDEPNA 255
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
FG T LHIA A + L++ G +V + G + L
Sbjct: 256 FGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPL 294
Score = 48.0 bits (109), Expect = 1e-04
Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSAC 368
A+V AKD PLH A +R + LLL+ AD NA D TPLH+AA N + C
Sbjct: 83 ANVNAKDTLWLAPLHRAAA--SRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKC 140
Query: 369 VLLLLDYGGDVTLRTNGGVSALSFIV 394
L + + G SAL V
Sbjct: 141 AEALAPLLSSLNVADRSGRSALHHAV 166
Score = 42.7 bits (96), Expect = 0.005
Identities = 41/123 (33%), Positives = 53/123 (43%), Gaps = 6/123 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R + WA +LG +L L+ G D D G LH + G E VK LL GA
Sbjct: 192 RQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAE-- 249
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVK 202
D T LH A A L+ GA+VN +D+ +PLH A +S +
Sbjct: 250 -IDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQP-NDKGFTPLHVAAVSTNGALCL 307
Query: 203 ELL 205
ELL
Sbjct: 308 ELL 310
>AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens
cDNA FLJ39787 fis, clone SPLEN2002744, weakly similar to
ANKYRIN 2. ).
Length = 819
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 330 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 388
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 389 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 446
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 447 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 504
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 505 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 564
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 565 GDTALHVALQR 575
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 306 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 363
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 364 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 422
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 423 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 481
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 482 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 540
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 541 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 589
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 277 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 331
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 332 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 391
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 392 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 450
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 451 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 510
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 511 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 568
Query: 390 LSFIVRR 396
L ++R
Sbjct: 569 LHVALQR 575
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 455 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 512
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 513 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 572
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 573 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 629
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 630 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 685
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 686 GAAPGPEAAECLVCSELALLVL--FSPC 711
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 294 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 349
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 350 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 409
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 410 VVRALCE 416
>AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens
cDNA FLJ38976 fis, clone NT2RI2004099, weakly similar to
ANKYRIN 2. ).
Length = 681
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 192 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 250
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 251 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 308
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 309 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKEEDGFTALHL 366
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 367 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 426
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 427 GDTALHVALQR 437
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 168 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 225
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 226 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 284
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 285 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 343
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 344 KILARARQLVDAKEEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 402
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 403 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 451
Score = 81.8 bits (193), Expect = 8e-15
Identities = 86/307 (28%), Positives = 133/307 (43%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 139 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 193
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 194 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 253
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 254 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 312
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK+ DG T LH A +
Sbjct: 313 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKEEDGFTALHLAALNNH 372
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 373 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 430
Query: 390 LSFIVRR 396
L ++R
Sbjct: 431 LHVALQR 437
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 317 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKEEDGFTALHLAALNNHRE 374
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 375 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 434
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 435 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 491
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 492 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 547
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 548 GAAPGPEAAECLVCSELALLVL--FSPC 573
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 156 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 211
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 212 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 271
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 272 VVRALCE 278
>AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens
cDNA FLJ38595 fis, clone HEART2001773, weakly similar to
ANKYRIN 2. ).
Length = 681
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 192 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 250
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 251 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 308
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 309 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 366
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 367 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 426
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 427 GDTALHVALQR 437
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 168 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 225
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 226 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 284
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 285 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 343
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 344 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 402
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 403 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 451
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 139 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 193
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 194 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 253
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 254 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 312
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 313 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 372
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 373 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 430
Query: 390 LSFIVRR 396
L ++R
Sbjct: 431 LHVALQR 437
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 317 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 374
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 375 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 434
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 435 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 491
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 492 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 547
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 548 GAAPGPEAAECLVCSELALLVL--FSPC 573
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 156 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 211
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 212 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 271
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 272 VVRALCE 278
>AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens
cDNA FLJ34291 fis, clone FEBRA2004620, weakly similar to
ANKYRIN 2. ).
Length = 645
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 156 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 214
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 215 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 272
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 273 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 330
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 331 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 390
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 391 GDTALHVALQR 401
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 132 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 189
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 190 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 248
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 249 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 307
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 308 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 366
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 367 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 415
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 103 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 157
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 158 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 217
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 218 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 276
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 277 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 336
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 337 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 394
Query: 390 LSFIVRR 396
L ++R
Sbjct: 395 LHVALQR 401
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 281 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 338
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 339 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 398
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 399 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 455
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 456 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 511
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 512 GAAPGPEAAECLVCSELALLVL--FSPC 537
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 120 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 175
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 176 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 235
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 236 VVRALCE 242
>AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activating
protein protein.
Length = 999
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 510 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 568
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 569 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 626
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 627 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 684
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 685 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 744
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 745 GDTALHVALQR 755
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 486 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 543
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 544 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 602
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 603 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 661
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 662 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 720
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 721 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 769
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 457 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 511
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 512 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 571
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 572 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 630
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 631 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 690
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 691 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 748
Query: 390 LSFIVRR 396
L ++R
Sbjct: 749 LHVALQR 755
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 635 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 692
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 693 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 752
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 753 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 809
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 810 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 865
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 866 GAAPGPEAAECLVCSELALLVL--FSPC 891
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 474 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 529
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 530 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 589
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 590 VVRALCE 596
>AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma
protein.
Length = 1009
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 520 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 578
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 579 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 636
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 637 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 694
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 695 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 754
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 755 GDTALHVALQR 765
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 496 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 553
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 554 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 612
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 613 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 671
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 672 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 730
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 731 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 779
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 467 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 521
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 522 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 581
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 582 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 640
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 641 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 700
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 701 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 758
Query: 390 LSFIVRR 396
L ++R
Sbjct: 759 LHVALQR 765
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 645 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 702
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 703 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 762
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 763 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 819
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 820 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 875
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 876 GAAPGPEAAECLVCSELALLVL--FSPC 901
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 484 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 539
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 540 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 599
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 600 VVRALCE 606
>AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein.
Length = 948
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 459 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 517
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 518 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 575
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 576 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 633
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 634 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 693
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 694 GDTALHVALQR 704
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 435 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 492
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 493 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 551
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 552 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 610
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 611 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 669
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 670 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 718
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 406 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 460
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 461 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 520
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 521 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 579
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 580 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 639
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 640 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 697
Query: 390 LSFIVRR 396
L ++R
Sbjct: 698 LHVALQR 704
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 584 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 641
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 642 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 701
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 702 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 758
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 759 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 814
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 815 GAAPGPEAAECLVCSELALLVL--FSPC 840
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 423 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 478
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 479 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 538
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 539 VVRALCE 545
>AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha
protein.
Length = 999
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 510 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 568
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 569 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 626
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 627 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 684
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 685 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 744
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 745 GDTALHVALQR 755
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 486 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 543
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 544 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 602
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 603 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 661
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 662 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 720
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 721 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 769
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 457 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 511
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 512 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 571
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 572 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 630
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 631 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 690
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 691 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 748
Query: 390 LSFIVRR 396
L ++R
Sbjct: 749 LHVALQR 755
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 635 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 692
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 693 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 752
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 753 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 809
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 810 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 865
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 866 GAAPGPEAAECLVCSELALLVL--FSPC 891
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 474 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 529
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 530 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 589
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 590 VVRALCE 596
>AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein.
Length = 1013
Score = 107 bits (256), Expect = 2e-22
Identities = 84/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 524 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 582
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAV-----LSDAP 198
D+ T++T LH A L V+ L G DVN +PLH A+ S
Sbjct: 583 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 640
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 641 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 698
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 699 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 758
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 759 GDTALHVALQR 769
Score = 105 bits (253), Expect = 4e-22
Identities = 93/292 (31%), Positives = 135/292 (46%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 500 LGNAARALDLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 557
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 558 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 616
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G++ ++L DV A G T LH A+ GHA R
Sbjct: 617 LPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 675
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 676 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 734
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 735 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 783
Score = 80.6 bits (190), Expect = 2e-14
Identities = 86/307 (28%), Positives = 132/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 471 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALDLLR---RRPEQVDTKNQGR-T 525
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 526 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 585
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G + +L
Sbjct: 586 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGASGIVEVLT 644
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 645 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 704
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 705 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 762
Query: 390 LSFIVRR 396
L ++R
Sbjct: 763 LHVALQR 769
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 649 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 706
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 707 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 766
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 767 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 823
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 824 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 879
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 880 GAAPGPEAAECLVCSELALLVL--FSPC 905
Score = 38.3 bits (85), Expect = 0.098
Identities = 38/127 (29%), Positives = 56/127 (44%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + +++L R V K+ GRT L A G ++ RLLL
Sbjct: 488 PEHPGRLVVEVA-LGNAARALDLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 543
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 544 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 603
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 604 VVRALCE 610
>BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein.
Length = 999
Score = 105 bits (253), Expect = 4e-22
Identities = 83/251 (33%), Positives = 118/251 (47%), Gaps = 12/251 (4%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA+ A +LG+ L+ LL+ D DD G T LH + L E ++LL G
Sbjct: 510 RTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRA- 568
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDA-----P 198
D+ T++T LH A L V+ L G DVN +PLH A+ +
Sbjct: 569 --DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSAISAGTGAGGIV 626
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
EV+ E+ Q F T LH A+ G A + +L + A TALHL
Sbjct: 627 EVLTEVPNIDVTATNSQGF--TLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 684
Query: 259 AAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
AA + H E A++L+ G ++ N + Q+PLHLA + +V +LVD V A+D +
Sbjct: 685 AALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEE 744
Query: 318 GRTPLHGAIVR 328
G T LH A+ R
Sbjct: 745 GDTALHVALQR 755
Score = 105 bits (251), Expect = 8e-22
Identities = 93/292 (31%), Positives = 134/292 (45%), Gaps = 15/292 (5%)
Query: 94 LGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETK 153
LG + LL+ + + + GRT L ++ +G E ++LLL A + D
Sbjct: 486 LGNAARALGLLRRRPEQVDTKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGN-- 543
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPD 212
T LH AA +VL++ G +A S +S LH AV EVV+ L E G +
Sbjct: 544 -TALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVN 602
Query: 213 TPQVFTETPLH--VAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAAEDGHAECAR 269
P ++TPLH ++A G+ ++L DV A G T LH A+ GHA R
Sbjct: 603 LPDAHSDTPLHSAISAGTGAGGIVEVLTEVPNIDVTATNSQG-FTLLHHASLKGHALAVR 661
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLV--DRCADVRAKDADGRTPLHGAI 326
+L +D G T LHLA L EV ++L+ RC DV ++ ++PLH A+
Sbjct: 662 KILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRC-DVNVRNRKLQSPLHLAV 720
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+ + LL+ AG NA D G T LH+ AL L+ GGD
Sbjct: 721 QQA--HVGLVPLLVDAGCSVNAEDEEGDTALHV-ALQRHQLLPLVADGAGGD 769
Score = 79.8 bits (188), Expect = 3e-14
Identities = 86/307 (28%), Positives = 131/307 (42%), Gaps = 14/307 (4%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
KS L L K+ + + GR + ++ L + + LL P D+ + + T
Sbjct: 457 KSSLSVALDKLRAQKSDPEHPGRLVVEVA-LGNAARALGLLR---RRPEQVDTKNQGR-T 511
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTP 214
L AA + +++L+ A V+ + + LHYA L + PE + LL AG D
Sbjct: 512 ALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAI 571
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH--LAAEDGHAECARLLL 272
T LHVA G + L G DV T LH ++A G +L
Sbjct: 572 NSTQSTALHVAVQRGFLEVVRALCERGCDVNLP-DAHSDTPLHSAISAGTGAGGIVEVLT 630
Query: 273 D-HGAHIDWPNFRGQTPLHLATL-AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
+ + N +G T LH A+L +L V ++L V AK DG T LH A +
Sbjct: 631 EVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNH 690
Query: 331 RACDIARLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
R ++A++L+ G D N + +PLH+A V LL+D G V G +A
Sbjct: 691 R--EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTA 748
Query: 390 LSFIVRR 396
L ++R
Sbjct: 749 LHVALQR 755
Score = 52.0 bits (119), Expect = 7e-06
Identities = 75/268 (27%), Positives = 111/268 (41%), Gaps = 18/268 (6%)
Query: 108 VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLA 167
+D + G T LH + L G V+ +L D+ E T LH AA
Sbjct: 635 IDVTATNSQGFTLLHHASLKGHALAVRKILARARQ--LVDAKKEDGFTALHLAALNNHRE 692
Query: 168 CVKVLIAHG-ADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVA 225
++LI G DVN +SPLH AV +V L++AG + +T LHVA
Sbjct: 693 VAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVA 752
Query: 226 ASLGSASCTKLLLN-AGADVRAA--MGPGKATALHLAAE--DGHAECARLLLDHGAHIDW 280
L L+ + AG D + +A+ L +AE G A L L+ GA + +
Sbjct: 753 --LQRHQLLPLVADGAGGDPGPLQLLSRLQASGLPGSAELTVGAAVACFLALE-GADVSY 809
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
N RG++PL LA + L+ ++ R + +A G P G + L +
Sbjct: 810 TNHRGRSPLDLAAEGRVLKALQGCAQRFRERQA--GGGAAP--GPRQTLGTPNTVTNLHV 865
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSAC 368
A P AA+ + L + L FS C
Sbjct: 866 GAAPGPEAAECLVCSELALLVL--FSPC 891
Score = 36.7 bits (81), Expect = 0.30
Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 4/127 (3%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P G+ + +A L + + +L R V K+ GRT L A G ++ RLLL
Sbjct: 474 PEHPGRLVVEVA-LGNAARALGLLRRRPEQVDTKN-QGRTALQVAAYLGQ--VELIRLLL 529
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDV 400
A A + D+ G T LH AAL +LL G + +AL V+R
Sbjct: 530 QARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLE 589
Query: 401 IPRYLCK 407
+ R LC+
Sbjct: 590 VVRALCE 596
>D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein.
Length = 1180
Score = 105 bits (252), Expect = 6e-22
Identities = 77/214 (35%), Positives = 113/214 (52%), Gaps = 6/214 (2%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVR 245
+PLH+A L+ +VV+ LL A + PLH+AA G A +LL++ G + R
Sbjct: 128 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 187
Query: 246 A-AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
TALH AA+ GH E ++LL+ N + +TPL LA L LEVV+ML
Sbjct: 188 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 247
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
++ ++ + + TPLH A G +A + ++LL AG D N G + LH AAL
Sbjct: 248 LNAHPNLLSCNTKKHTPLHLAARNGHKA--VVQVLLDAGMDSNYQTEMG-SALHEAALFG 304
Query: 365 FSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
+ V +LL G DV ++ N G++AL VR +P
Sbjct: 305 KTDVVQILLAAGTDVNIKDNHGLTALD-TVRELP 337
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/207 (30%), Positives = 94/207 (45%), Gaps = 6/207 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG---A 276
TPLH AA G ++LL A A G LHLAA G A+ RLL+ G
Sbjct: 128 TPLHHAALNGHKDVVEVLLRNDALTNVADSKG-CYPLHLAAWKGDAQIVRLLIHQGPSHT 186
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ N +T LH A EVV++L++ D ++ TPL A + G ++
Sbjct: 187 RVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGR--LEVV 244
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
++LL+A + + + +TPLH+AA N A V +LLD G D +T G + +
Sbjct: 245 KMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFG 304
Query: 397 VPDVIPRYLCKFDDAVHVSEHELGDVD 423
DV+ L D H L +D
Sbjct: 305 KTDVVQILLAAGTDVNIKDNHGLTALD 331
Score = 72.1 bits (169), Expect = 7e-12
Identities = 62/212 (29%), Positives = 90/212 (42%), Gaps = 6/212 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D G LHL+ G + V+LL+ G + T LHCAA VKVL+
Sbjct: 156 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL 215
Query: 174 AHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
D + +PL A L EVVK LL A + TPLH+AA G +
Sbjct: 216 EELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKA 275
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
++LL+AG D G +ALH AA G + ++LL G ++ + G T L
Sbjct: 276 VVQVLLDAGMDSNYQTEMG--SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTV 333
Query: 293 ---TLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+S ++ ++ D R+ +TP
Sbjct: 334 RELPSQKSQQIAALIEDHMTGKRSTKEVDKTP 365
Score = 62.5 bits (145), Expect = 5e-09
Identities = 48/123 (39%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + ++ LL+ DP ++ T L L+ L G E VK+LL+ AHPN
Sbjct: 197 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLN--AHPNL 254
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+T+ K TPLH AA A V+VL+ G D N S LH A L +VV+ LL
Sbjct: 255 LSCNTK-KHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 313
Query: 206 EAG 208
AG
Sbjct: 314 AAG 316
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + L + G +++ + G TPLH A L +VVE+L+ A D+ G PLH
Sbjct: 105 HPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLH 164
Query: 324 GAIVRGARACDIARLLLSAGAD---PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
A +G I RLL+ G N +N T LH AA + V +LL+ D T
Sbjct: 165 LAAWKG--DAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 222
Query: 381 LRTN 384
+R N
Sbjct: 223 MRNN 226
>BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 105 bits (252), Expect = 6e-22
Identities = 77/214 (35%), Positives = 113/214 (52%), Gaps = 6/214 (2%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVR 245
+PLH+A L+ +VV+ LL A + PLH+AA G A +LL++ G + R
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 246 A-AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
TALH AA+ GH E ++LL+ N + +TPL LA L LEVV+ML
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
++ ++ + + TPLH A G +A + ++LL AG D N G + LH AAL
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKA--VVQVLLDAGMDSNYQTEMG-SALHEAALFG 258
Query: 365 FSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
+ V +LL G DV ++ N G++AL VR +P
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD-TVRELP 291
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/207 (30%), Positives = 94/207 (45%), Gaps = 6/207 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG---A 276
TPLH AA G ++LL A A G LHLAA G A+ RLL+ G
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKG-CYPLHLAAWKGDAQIVRLLIHQGPSHT 140
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ N +T LH A EVV++L++ D ++ TPL A + G ++
Sbjct: 141 RVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGR--LEVV 198
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
++LL+A + + + +TPLH+AA N A V +LLD G D +T G + +
Sbjct: 199 KMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFG 258
Query: 397 VPDVIPRYLCKFDDAVHVSEHELGDVD 423
DV+ L D H L +D
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD 285
Score = 72.1 bits (169), Expect = 7e-12
Identities = 62/212 (29%), Positives = 90/212 (42%), Gaps = 6/212 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D G LHL+ G + V+LL+ G + T LHCAA VKVL+
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL 169
Query: 174 AHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
D + +PL A L EVVK LL A + TPLH+AA G +
Sbjct: 170 EELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKA 229
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
++LL+AG D G +ALH AA G + ++LL G ++ + G T L
Sbjct: 230 VVQVLLDAGMDSNYQTEMG--SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTV 287
Query: 293 ---TLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+S ++ ++ D R+ +TP
Sbjct: 288 RELPSQKSQQIAALIEDHMTGKRSTKEVDKTP 319
Score = 62.5 bits (145), Expect = 5e-09
Identities = 48/123 (39%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + ++ LL+ DP ++ T L L+ L G E VK+LL+ AHPN
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLN--AHPNL 208
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+T+ K TPLH AA A V+VL+ G D N S LH A L +VV+ LL
Sbjct: 209 LSCNTK-KHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 267
Query: 206 EAG 208
AG
Sbjct: 268 AAG 270
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + L + G +++ + G TPLH A L +VVE+L+ A D+ G PLH
Sbjct: 59 HPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLH 118
Query: 324 GAIVRGARACDIARLLLSAGAD---PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
A +G I RLL+ G N +N T LH AA + V +LL+ D T
Sbjct: 119 LAAWKG--DAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 176
Query: 381 LRTN 384
+R N
Sbjct: 177 MRNN 180
>BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for
IMAGE:4618556) protein.
Length = 472
Score = 105 bits (252), Expect = 6e-22
Identities = 77/214 (35%), Positives = 113/214 (52%), Gaps = 6/214 (2%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVR 245
+PLH+A L+ +VV+ LL A + PLH+AA G A +LL++ G + R
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 246 A-AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
TALH AA+ GH E ++LL+ N + +TPL LA L LEVV+ML
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
++ ++ + + TPLH A G +A + ++LL AG D N G + LH AAL
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKA--VVQVLLDAGMDSNYQTEMG-SALHEAALFG 258
Query: 365 FSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
+ V +LL G DV ++ N G++AL VR +P
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD-TVRELP 291
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/207 (30%), Positives = 94/207 (45%), Gaps = 6/207 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG---A 276
TPLH AA G ++LL A A G LHLAA G A+ RLL+ G
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKG-CYPLHLAAWKGDAQIVRLLIHQGPSHT 140
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ N +T LH A EVV++L++ D ++ TPL A + G ++
Sbjct: 141 RVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGR--LEVV 198
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
++LL+A + + + +TPLH+AA N A V +LLD G D +T G + +
Sbjct: 199 KMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFG 258
Query: 397 VPDVIPRYLCKFDDAVHVSEHELGDVD 423
DV+ L D H L +D
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD 285
Score = 72.1 bits (169), Expect = 7e-12
Identities = 62/212 (29%), Positives = 90/212 (42%), Gaps = 6/212 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D G LHL+ G + V+LL+ G + T LHCAA VKVL+
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL 169
Query: 174 AHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
D + +PL A L EVVK LL A + TPLH+AA G +
Sbjct: 170 EELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKA 229
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
++LL+AG D G +ALH AA G + ++LL G ++ + G T L
Sbjct: 230 VVQVLLDAGMDSNYQTEMG--SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTV 287
Query: 293 ---TLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+S ++ ++ D R+ +TP
Sbjct: 288 RELPSQKSQQIAALIEDHMTGKRSTKEVDKTP 319
Score = 62.5 bits (145), Expect = 5e-09
Identities = 48/123 (39%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + ++ LL+ DP ++ T L L+ L G E VK+LL+ AHPN
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLN--AHPNL 208
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+T+ K TPLH AA A V+VL+ G D N S LH A L +VV+ LL
Sbjct: 209 LSCNTK-KHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 267
Query: 206 EAG 208
AG
Sbjct: 268 AAG 270
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + L + G +++ + G TPLH A L +VVE+L+ A D+ G PLH
Sbjct: 59 HPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLH 118
Query: 324 GAIVRGARACDIARLLLSAGAD---PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
A +G I RLL+ G N +N T LH AA + V +LL+ D T
Sbjct: 119 LAAWKG--DAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 176
Query: 381 LRTN 384
+R N
Sbjct: 177 MRNN 180
>AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 105 bits (252), Expect = 6e-22
Identities = 77/214 (35%), Positives = 113/214 (52%), Gaps = 6/214 (2%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVR 245
+PLH+A L+ +VV+ LL A + PLH+AA G A +LL++ G + R
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 246 A-AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
TALH AA+ GH E ++LL+ N + +TPL LA L LEVV+ML
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
++ ++ + + TPLH A G +A + ++LL AG D N G + LH AAL
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKA--VVQVLLDAGMDSNYQTEMG-SALHEAALFG 258
Query: 365 FSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
+ V +LL G DV ++ N G++AL VR +P
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD-TVRELP 291
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/207 (30%), Positives = 94/207 (45%), Gaps = 6/207 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG---A 276
TPLH AA G ++LL A A G LHLAA G A+ RLL+ G
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKG-CYPLHLAAWKGDAQIVRLLIHQGPSHT 140
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ N +T LH A EVV++L++ D ++ TPL A + G ++
Sbjct: 141 RVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGR--LEVV 198
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
++LL+A + + + +TPLH+AA N A V +LLD G D +T G + +
Sbjct: 199 KMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFG 258
Query: 397 VPDVIPRYLCKFDDAVHVSEHELGDVD 423
DV+ L D H L +D
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD 285
Score = 72.1 bits (169), Expect = 7e-12
Identities = 62/212 (29%), Positives = 90/212 (42%), Gaps = 6/212 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D G LHL+ G + V+LL+ G + T LHCAA VKVL+
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL 169
Query: 174 AHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
D + +PL A L EVVK LL A + TPLH+AA G +
Sbjct: 170 EELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKA 229
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
++LL+AG D G +ALH AA G + ++LL G ++ + G T L
Sbjct: 230 VVQVLLDAGMDSNYQTEMG--SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTV 287
Query: 293 ---TLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+S ++ ++ D R+ +TP
Sbjct: 288 RELPSQKSQQIAALIEDHMTGKRSTKEVDKTP 319
Score = 62.5 bits (145), Expect = 5e-09
Identities = 48/123 (39%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + ++ LL+ DP ++ T L L+ L G E VK+LL+ AHPN
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLN--AHPNL 208
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+T+ K TPLH AA A V+VL+ G D N S LH A L +VV+ LL
Sbjct: 209 LSCNTK-KHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 267
Query: 206 EAG 208
AG
Sbjct: 268 AAG 270
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + L + G +++ + G TPLH A L +VVE+L+ A D+ G PLH
Sbjct: 59 HPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLH 118
Query: 324 GAIVRGARACDIARLLLSAGAD---PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
A +G I RLL+ G N +N T LH AA + V +LL+ D T
Sbjct: 119 LAAWKG--DAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 176
Query: 381 LRTN 384
+R N
Sbjct: 177 MRNN 180
>AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 105 bits (252), Expect = 6e-22
Identities = 77/214 (35%), Positives = 113/214 (52%), Gaps = 6/214 (2%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVR 245
+PLH+A L+ +VV+ LL A + PLH+AA G A +LL++ G + R
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 246 A-AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
TALH AA+ GH E ++LL+ N + +TPL LA L LEVV+ML
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
++ ++ + + TPLH A G +A + ++LL AG D N G + LH AAL
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKA--VVQVLLDAGMDSNYQTEMG-SALHEAALFG 258
Query: 365 FSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
+ V +LL G DV ++ N G++AL VR +P
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD-TVRELP 291
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/207 (30%), Positives = 94/207 (45%), Gaps = 6/207 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG---A 276
TPLH AA G ++LL A A G LHLAA G A+ RLL+ G
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKG-CYPLHLAAWKGDAQIVRLLIHQGPSHT 140
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ N +T LH A EVV++L++ D ++ TPL A + G ++
Sbjct: 141 RVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGR--LEVV 198
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
++LL+A + + + +TPLH+AA N A V +LLD G D +T G + +
Sbjct: 199 KMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFG 258
Query: 397 VPDVIPRYLCKFDDAVHVSEHELGDVD 423
DV+ L D H L +D
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD 285
Score = 72.1 bits (169), Expect = 7e-12
Identities = 62/212 (29%), Positives = 90/212 (42%), Gaps = 6/212 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D G LHL+ G + V+LL+ G + T LHCAA VKVL+
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL 169
Query: 174 AHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
D + +PL A L EVVK LL A + TPLH+AA G +
Sbjct: 170 EELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKA 229
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
++LL+AG D G +ALH AA G + ++LL G ++ + G T L
Sbjct: 230 VVQVLLDAGMDSNYQTEMG--SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTV 287
Query: 293 ---TLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+S ++ ++ D R+ +TP
Sbjct: 288 RELPSQKSQQIAALIEDHMTGKRSTKEVDKTP 319
Score = 62.5 bits (145), Expect = 5e-09
Identities = 48/123 (39%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + ++ LL+ DP ++ T L L+ L G E VK+LL+ AHPN
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLN--AHPNL 208
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+T+ K TPLH AA A V+VL+ G D N S LH A L +VV+ LL
Sbjct: 209 LSCNTK-KHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 267
Query: 206 EAG 208
AG
Sbjct: 268 AAG 270
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + L + G +++ + G TPLH A L +VVE+L+ A D+ G PLH
Sbjct: 59 HPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLH 118
Query: 324 GAIVRGARACDIARLLLSAGAD---PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
A +G I RLL+ G N +N T LH AA + V +LL+ D T
Sbjct: 119 LAAWKG--DAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 176
Query: 381 LRTN 384
+R N
Sbjct: 177 MRNN 180
>AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and sterile
alpha motif domain containing 1A protein.
Length = 1134
Score = 105 bits (252), Expect = 6e-22
Identities = 77/214 (35%), Positives = 113/214 (52%), Gaps = 6/214 (2%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVR 245
+PLH+A L+ +VV+ LL A + PLH+AA G A +LL++ G + R
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTR 141
Query: 246 A-AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
TALH AA+ GH E ++LL+ N + +TPL LA L LEVV+ML
Sbjct: 142 VNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKML 201
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNE 364
++ ++ + + TPLH A G +A + ++LL AG D N G + LH AAL
Sbjct: 202 LNAHPNLLSCNTKKHTPLHLAARNGHKA--VVQVLLDAGMDSNYQTEMG-SALHEAALFG 258
Query: 365 FSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
+ V +LL G DV ++ N G++AL VR +P
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD-TVRELP 291
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/207 (30%), Positives = 94/207 (45%), Gaps = 6/207 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG---A 276
TPLH AA G ++LL A A G LHLAA G A+ RLL+ G
Sbjct: 82 TPLHHAALNGHKDVVEVLLRNDALTNVADSKG-CYPLHLAAWKGDAQIVRLLIHQGPSHT 140
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++ N +T LH A EVV++L++ D ++ TPL A + G ++
Sbjct: 141 RVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGR--LEVV 198
Query: 337 RLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRR 396
++LL+A + + + +TPLH+AA N A V +LLD G D +T G + +
Sbjct: 199 KMLLNAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFG 258
Query: 397 VPDVIPRYLCKFDDAVHVSEHELGDVD 423
DV+ L D H L +D
Sbjct: 259 KTDVVQILLAAGTDVNIKDNHGLTALD 285
Score = 72.1 bits (169), Expect = 7e-12
Identities = 62/212 (29%), Positives = 90/212 (42%), Gaps = 6/212 (2%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI 173
D G LHL+ G + V+LL+ G + T LHCAA VKVL+
Sbjct: 110 DSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLL 169
Query: 174 AHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSAS 232
D + +PL A L EVVK LL A + TPLH+AA G +
Sbjct: 170 EELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHKA 229
Query: 233 CTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA 292
++LL+AG D G +ALH AA G + ++LL G ++ + G T L
Sbjct: 230 VVQVLLDAGMDSNYQTEMG--SALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTV 287
Query: 293 ---TLAQSLEVVEMLVDRCADVRAKDADGRTP 321
+S ++ ++ D R+ +TP
Sbjct: 288 RELPSQKSQQIAALIEDHMTGKRSTKEVDKTP 319
Score = 62.5 bits (145), Expect = 5e-09
Identities = 48/123 (39%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G + ++ LL+ DP ++ T L L+ L G E VK+LL+ AHPN
Sbjct: 151 TALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLN--AHPNL 208
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
+T+ K TPLH AA A V+VL+ G D N S LH A L +VV+ LL
Sbjct: 209 LSCNTK-KHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILL 267
Query: 206 EAG 208
AG
Sbjct: 268 AAG 270
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/124 (33%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH 323
H + L + G +++ + G TPLH A L +VVE+L+ A D+ G PLH
Sbjct: 59 HPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLH 118
Query: 324 GAIVRGARACDIARLLLSAGAD---PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVT 380
A +G I RLL+ G N +N T LH AA + V +LL+ D T
Sbjct: 119 LAAWKG--DAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPT 176
Query: 381 LRTN 384
+R N
Sbjct: 177 MRNN 180
>AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens
cDNA FLJ34236 fis, clone FCBBF3027199, weakly similar to
ANKYRIN. ).
Length = 505
Score = 105 bits (252), Expect = 6e-22
Identities = 93/309 (30%), Positives = 145/309 (46%), Gaps = 14/309 (4%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A + G L L + V+ D D GRT L L+ GS ECV++L HGA +
Sbjct: 21 AAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGA--SALIKER 78
Query: 151 ETKATPLHCAASAKSLACVKVLIAHG--ADVN--AGLSDRSPLHYAVLSDAPEVVKELLE 206
+ K TPLH AA++ + +LI G AD+ + ++PL A+++ + V LLE
Sbjct: 79 KRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDVYGQTPLMLAIMNGHVDCVHLLLE 138
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE 266
G+ D + T LH A G C LL+ A V G+ T +HLA+ GH
Sbjct: 139 KGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGR-TPIHLASACGHTA 197
Query: 267 CARLLLDHGAHID----WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
R LL D ++ G +P+H A+ + +E+L++ + + + TPL
Sbjct: 198 VLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEH-SPFSYLEGNPFTPL 256
Query: 323 HGAIVRGARACDIARLLLSAGAD-PNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
H A++ + LL + GA N+ D G TPLH AA + + + +LL + +V
Sbjct: 257 HCAVINN-QDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFADNVSGLRMLLQHQAEVNA 315
Query: 382 RTNGGVSAL 390
+ G +AL
Sbjct: 316 TDHTGRTAL 324
Score = 105 bits (251), Expect = 8e-22
Identities = 98/309 (31%), Positives = 145/309 (46%), Gaps = 24/309 (7%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+T ++ A G + LL+ G D D GRT LH + G E+C+ LLDH A
Sbjct: 118 QTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVL 177
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLI--AHGAD-VNAGL--SDRSPLHYAVLSDAPE 199
D TP+H A++ A ++ L+ A D ++AG+ S SP+H+A + +
Sbjct: 178 CRDFKGR---TPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHED 234
Query: 200 VVKELLEAGACPDTPQVFTE----TPLHVAASLGSASCTKLLLNA-GADVRAAMGPGKAT 254
++ LLE +P + E TPLH A S T++LL A GA + + T
Sbjct: 235 CLELLLE-----HSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGRT 289
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDR-CADVRA 313
LH AA + R+LL H A ++ + G+T L A VE L+ R AD+
Sbjct: 290 PLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLTV 349
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGAD---PNAADNFGYTPLHIAALNEFSACVL 370
D + T LH A +G C A ++L+ D NA ++ PLHIAA N ++ V
Sbjct: 350 LDENKNTALHLACSKGHEKC--ALMILAETQDLGLINATNSALQMPLHIAARNGLASVVQ 407
Query: 371 LLLDYGGDV 379
LL +G V
Sbjct: 408 ALLSHGATV 416
Score = 95.9 bits (228), Expect = 5e-19
Identities = 89/287 (31%), Positives = 126/287 (43%), Gaps = 14/287 (4%)
Query: 111 DELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVK 170
D +D G+T L L+ + G +CV LLL+ G+ T D++ T LH A C+
Sbjct: 111 DVMDVYGQTPLMLAIMNGHVDCVHLLLEKGS---TADAADLRGRTALHRGAVTGCEDCLA 167
Query: 171 VLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE----TPLHVA 225
L+ H A V R+P+H A V++ LL+A D + +P+H A
Sbjct: 168 ALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWA 227
Query: 226 ASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GAHI-DWPNF 283
+ G C +LLL P T LH A + +LL GA I + +
Sbjct: 228 SYTGHEDCLELLLEHSPFSYLEGNP--FTPLHCAVINNQDSTTEMLLGALGAKIVNSRDT 285
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAG 343
+G+TPLH A A ++ + ML+ A+V A D GRT L A G A + LL
Sbjct: 286 KGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAA-VEFLLYRGK 344
Query: 344 ADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
AD D T LH+A C L++L D+ L N SAL
Sbjct: 345 ADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGL-INATNSAL 390
Score = 95.1 bits (226), Expect = 8e-19
Identities = 79/239 (33%), Positives = 112/239 (46%), Gaps = 14/239 (5%)
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD---RSPLHYAVLSDAPEVVKE 203
D + +PLH AA +K L VN + D R+ L A + E V+
Sbjct: 8 DVESTIPVSPLHLAAYNGHCEALKTLAE--TLVNLDVRDHKGRTALFLATERGSTECVEV 65
Query: 204 LLEAGACPDTPQVFTE-TPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAA 260
L GA + + TPLH AA+ G LL+++G AD+ M T L LA
Sbjct: 66 LTAHGASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDVYGQTPLMLAI 125
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
+GH +C LLL+ G+ D + RG+T LH + + + L+D A V +D GRT
Sbjct: 126 MNGHVDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDCLAALLDHDAFVLCRDFKGRT 185
Query: 321 PLHGAIVRGARACDIARLLLSA--GADPNAA--DNFGYTPLHIAALNEFSACVLLLLDY 375
P+H A G A + R LL A DP A D GY+P+H A+ C+ LLL++
Sbjct: 186 PIHLASACGHTA--VLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEH 242
Score = 93.9 bits (223), Expect = 2e-18
Identities = 79/248 (31%), Positives = 116/248 (46%), Gaps = 16/248 (6%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDD----AGRTCLHLSCLVGSEECVKLLLDHG 140
RT I A G + +L LL+ + D LD +G + +H + G E+C++LLL+H
Sbjct: 184 RTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHS 243
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLI-AHGADV--NAGLSDRSPLHYAVLSDA 197
P ++ TPLHCA + ++L+ A GA + + R+PLH A +D
Sbjct: 244 --PFSYLEGNPF--TPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFADN 299
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALH 257
++ LL+ A + T L AA G + + LL G + K TALH
Sbjct: 300 VSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFLLYRGKADLTVLDENKNTALH 359
Query: 258 LAAEDGHAECARLLL----DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
LA GH +CA ++L D G I+ N Q PLH+A VV+ L+ A V A
Sbjct: 360 LACSKGHEKCALMILAETQDLGL-INATNSALQMPLHIAARNGLASVVQALLSHGATVLA 418
Query: 314 KDADGRTP 321
D +G TP
Sbjct: 419 VDEEGHTP 426
Score = 83.4 bits (197), Expect = 3e-15
Identities = 78/268 (29%), Positives = 123/268 (45%), Gaps = 11/268 (4%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA-TPLHCAASAKSLACVKVL 172
D GRT +HL+ G ++ LL + D+ + +P+H A+ C+++L
Sbjct: 180 DFKGRTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELL 239
Query: 173 IAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEA-GA-CPDTPQVFTETPLHVAASLGS 230
+ H + +PLH AV+++ + LL A GA ++ TPLH AA +
Sbjct: 240 LEHSPFSYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDTKGRTPLHAAAFADN 299
Query: 231 ASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPL 289
S ++LL A+V A G+ TAL AAE+G LL G A + + T L
Sbjct: 300 VSGLRMLLQHQAEVNATDHTGR-TALMTAAENGQTAAVEFLLYRGKADLTVLDENKNTAL 358
Query: 290 HLATLAQSLEVVEMLVDRCAD---VRAKDADGRTPLHGAIVRGARACDIARLLLSAGADP 346
HLA + M++ D + A ++ + PLH A G + + + LLS GA
Sbjct: 359 HLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLAS--VVQALLSHGATV 416
Query: 347 NAADNFGYTPLHIAALN-EFSACVLLLL 373
A D G+TP A N + + C+ L+L
Sbjct: 417 LAVDEEGHTPALACAPNKDVADCLALIL 444
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 1613 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 1671
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 1672 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 1731
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 1732 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1788
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 1789 LGAARELRDQAGLA 1802
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 1585 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 1638
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 1639 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 1698
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 1699 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1756
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 1757 GADKDAQDN 1765
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 1609 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1668
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 1669 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 1725
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 1726 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 1784
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 1785 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 1636 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 1695
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 1696 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 1751
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 1752 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 1807
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 1703 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 1762
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 1763 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 1820 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 1877
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 1878 QARTWSVDLAARGGGA 1893
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 1735 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 1794
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 1795 LRDQAGLAPADVAH 1808
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 1609 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 1667
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 1668 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 1727
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 1728 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1784
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 1785 LGAARELRDQAGLA 1798
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 1581 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 1634
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 1635 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 1694
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 1695 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1752
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 1753 GADKDAQDN 1761
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 1605 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1664
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 1665 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 1721
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 1722 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 1780
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 1781 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1815
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 1632 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 1691
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 1692 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 1747
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 1748 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 1803
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 1699 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 1758
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 1759 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1815
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 1816 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 1873
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 1874 QARTWSVDLAARGGGA 1889
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 1731 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 1790
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 1791 LRDQAGLAPADVAH 1804
>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein
protein.
Length = 1095
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 705 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 763
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 764 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 823
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 824 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 880
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 881 LGAARELRDQAGLA 894
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 677 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 730
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 731 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 790
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 791 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 848
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 849 GADKDAQDN 857
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 701 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 760
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 761 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 817
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 818 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 876
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 877 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 911
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 728 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 787
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 788 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 843
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 844 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 899
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 795 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 854
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 855 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 911
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 912 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 969
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 970 QARTWSVDLAARGGGA 985
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 827 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 886
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 887 LRDQAGLAPADVAH 900
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 1613 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 1671
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 1672 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 1731
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 1732 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1788
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 1789 LGAARELRDQAGLA 1802
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 1585 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 1638
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 1639 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 1698
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 1699 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1756
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 1757 GADKDAQDN 1765
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 1609 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1668
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 1669 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 1725
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 1726 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 1784
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 1785 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 1636 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 1695
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 1696 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 1751
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 1752 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 1807
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 1703 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 1762
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 1763 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 1820 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 1877
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 1878 QARTWSVDLAARGGGA 1893
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 1735 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 1794
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 1795 LRDQAGLAPADVAH 1808
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 1613 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 1671
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 1672 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 1731
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 1732 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1788
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 1789 LGAARELRDQAGLA 1802
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 1585 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 1638
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 1639 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 1698
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 1699 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1756
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 1757 GADKDAQDN 1765
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 1609 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1668
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 1669 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 1725
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 1726 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 1784
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 1785 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 1636 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 1695
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 1696 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 1751
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 1752 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 1807
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 1703 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 1762
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 1763 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 1820 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 1877
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 1878 QARTWSVDLAARGGGA 1893
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 1735 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 1794
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 1795 LRDQAGLAPADVAH 1808
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 1613 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 1671
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 1672 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 1731
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 1732 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1788
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 1789 LGAARELRDQAGLA 1802
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 1585 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 1638
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 1639 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 1698
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 1699 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1756
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 1757 GADKDAQDN 1765
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 1609 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1668
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 1669 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 1725
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 1726 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 1784
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 1785 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 1636 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 1695
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 1696 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 1751
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 1752 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 1807
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 1703 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 1762
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 1763 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 1820 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 1877
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 1878 QARTWSVDLAARGGGA 1893
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 1735 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 1794
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 1795 LRDQAGLAPADVAH 1808
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 1613 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 1671
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 1672 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 1731
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 1732 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1788
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 1789 LGAARELRDQAGLA 1802
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 1585 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 1638
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 1639 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 1698
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 1699 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1756
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 1757 GADKDAQDN 1765
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 1609 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1668
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 1669 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 1725
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 1726 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 1784
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 1785 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 1636 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 1695
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 1696 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 1751
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 1752 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 1807
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 1703 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 1762
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 1763 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 1820 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 1877
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 1878 QARTWSVDLAARGGGA 1893
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 1735 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 1794
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 1795 LRDQAGLAPADVAH 1808
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 1613 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 1671
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 1672 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 1731
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 1732 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1788
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 1789 LGAARELRDQAGLA 1802
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 1585 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 1638
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 1639 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 1698
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 1699 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1756
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 1757 GADKDAQDN 1765
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 1609 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1668
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 1669 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 1725
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 1726 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 1784
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 1785 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 1636 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 1695
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 1696 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 1751
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 1752 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 1807
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 1703 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 1762
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 1763 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1819
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 1820 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 1877
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 1878 QARTWSVDLAARGGGA 1893
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 1735 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 1794
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 1795 LRDQAGLAPADVAH 1808
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2005
Score = 105 bits (251), Expect = 8e-22
Identities = 79/194 (40%), Positives = 96/194 (49%), Gaps = 7/194 (3%)
Query: 198 PEVVKELLEAGACPDTPQVFT-ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATAL 256
PE + LL+ GACP V T ETPLH+AA + + LL AGA+ G+ T L
Sbjct: 1615 PEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR-TPL 1673
Query: 257 HLA-AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
H A A D C LL +D G TPL LA ++VE L+ ADV A+D
Sbjct: 1674 HAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARD 1733
Query: 316 ADGRTPLH-GAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
G+T LH A V ARA AR LL AGAD +A DN TPL +AA LLL
Sbjct: 1734 KWGKTALHWAAAVNNARA---ARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1790
Query: 375 YGGDVTLRTNGGVS 388
G LR G++
Sbjct: 1791 LGAARELRDQAGLA 1804
Score = 77.8 bits (183), Expect = 1e-13
Identities = 64/189 (33%), Positives = 91/189 (48%), Gaps = 10/189 (5%)
Query: 198 PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATAL 256
P+ V L+ A C + ++ A LG + LL+ GA +A +G G+ T L
Sbjct: 1587 PDGVTPLMSAVCCGEV-----QSGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGE-TPL 1640
Query: 257 HLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV-DRCADVRAKD 315
HLAA AR LL+ GA+ + P+ G+TPLH A A + EV ++L+ R V A+
Sbjct: 1641 HLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDART 1700
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG TPL + D+ L++A AD A D +G T LH AA + LL
Sbjct: 1701 EDGTTPL--MLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQA 1758
Query: 376 GGDVTLRTN 384
G D + N
Sbjct: 1759 GADKDAQDN 1767
Score = 77.4 bits (182), Expect = 2e-13
Identities = 68/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 93 WLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTE 151
WLG LL G P G T LHL+ + LL+ GA+PN D +
Sbjct: 1611 WLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1670
Query: 152 TKATPLHCAASAKSL-ACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
T PLH A +A + C +L + V+A D +PL A ++V+EL+ A A
Sbjct: 1671 T---PLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQA 1727
Query: 210 CPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ +T LH AA++ +A + LL AGAD + A + T L LAA +G E A+
Sbjct: 1728 DVGARDKWGKTALHWAAAVNNARAARSLLQAGAD-KDAQDNREQTPLFLAAREGAVEVAQ 1786
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
LLL GA + + G P +A +++ +L
Sbjct: 1787 LLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1821
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/178 (33%), Positives = 76/178 (42%), Gaps = 10/178 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA---GAD 243
+PLH A P + LLEAGA P+ P TPLH A + + +LLL + D
Sbjct: 1638 TPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVD 1697
Query: 244 VRAAMGPGK-ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
R G A LA ED E D GA W G+T LH A +
Sbjct: 1698 ARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKW----GKTALHWAAAVNNARAAR 1753
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L+ AD A+D +TPL A G A ++A+LLL GA D G P +A
Sbjct: 1754 SLLQAGADKDAQDNREQTPLFLAAREG--AVEVAQLLLGLGAARELRDQAGLAPADVA 1809
Score = 36.3 bits (80), Expect = 0.40
Identities = 51/196 (26%), Positives = 75/196 (38%), Gaps = 21/196 (10%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A L L+ +L+ D D G+T LH + V + + LL GA +
Sbjct: 1705 TPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDA 1764
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGA----DVNAGLSDRSPLH-------YAVL 194
D+ + TPL AA ++ ++L+ GA AGL+ H +L
Sbjct: 1765 QDNREQ---TPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLL 1821
Query: 195 SDA--PEVVKELL---EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
A PE + EAG P V P H +L C L AG A
Sbjct: 1822 EGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGAL--PRCRTLSAGAGPRGGGACL 1879
Query: 250 PGKATALHLAAEDGHA 265
+ ++ LAA G A
Sbjct: 1880 QARTWSVDLAARGGGA 1895
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/74 (31%), Positives = 34/74 (45%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
+TA+ WA + + LL+ G D D D+ +T L L+ G+ E +LLL GA
Sbjct: 1737 KTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARE 1796
Query: 145 TWDSSTETKATPLH 158
D + A H
Sbjct: 1797 LRDQAGLAPADVAH 1810
>BC103875-1|AAI03876.1| 323|Homo sapiens ankyrin repeat and SOCS
box-containing 11 protein.
Length = 323
Score = 104 bits (250), Expect = 1e-21
Identities = 83/246 (33%), Positives = 114/246 (46%), Gaps = 9/246 (3%)
Query: 63 IGNGNYDETIQFASEAEGG----FGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGR 118
I GN E + A E GG + R+ + A G+ + L L+ GV+ + +
Sbjct: 40 IVKGNRKEAARIAEEIYGGISDCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRV 99
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ LH +CL G C K LL++GAH N T ATPL A + S ACV VL+ GA
Sbjct: 100 SSLHEACLGGHVACAKALLENGAHVN---GVTVHGATPLFNACCSGSAACVNVLLEFGAK 156
Query: 179 VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLL 238
+ SP+H AV E ++ LL D TPL+VA + C K LL
Sbjct: 157 AQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLL 216
Query: 239 NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSL 298
GA V G T LH AA + E LL D+GA++ N +G++ L LA S+
Sbjct: 217 ELGASV--DHGQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSV 274
Query: 299 EVVEML 304
E +L
Sbjct: 275 EQALLL 280
Score = 91.5 bits (217), Expect = 1e-17
Identities = 77/220 (35%), Positives = 109/220 (49%), Gaps = 8/220 (3%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+PLH AA+ L +K LIA G +VN +R S LH A L K LLE GA +
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNG 126
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
V TPL A GSA+C +LL GA +A + A+ +H A + GH EC +LL
Sbjct: 127 VTVHGATPLFNACCSGSAACVNVLLEFGA--KAQLEVHLASPIHEAVKRGHRECMEILLA 184
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTPLHGAIVRGARA 332
+ +ID + TPL++A Q ++ V+ L++ A V + D TPLH A R +
Sbjct: 185 NNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TPLHAA-ARQSNV 241
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
++ LL GA+ + G + L +AA LLL
Sbjct: 242 -EVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLL 280
Score = 75.4 bits (177), Expect = 7e-13
Identities = 51/160 (31%), Positives = 78/160 (48%), Gaps = 4/160 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
+PLH AA+ G K L+ G +V + ++LH A GH CA+ LL++GAH++
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVT-INRVSSLHEACLGGHVACAKALLENGAHVN 125
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
G TPL A + S V +L++ A + + +P+H A+ RG R C L
Sbjct: 126 GVTVHGATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEILLA 184
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ D + G TPL++A + CV LL+ G V
Sbjct: 185 NNVNID-HEVPQLG-TPLYVACTYQRVDCVKKLLELGASV 222
Score = 73.7 bits (173), Expect = 2e-12
Identities = 64/207 (30%), Positives = 88/207 (42%), Gaps = 5/207 (2%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
+DRSPLH A +K L+ G + + + LH A G +C K LL GA
Sbjct: 64 ADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAH 123
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V G AT L A G A C +LL+ GA +P+H A E +E+
Sbjct: 124 VNGVTVHG-ATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEI 181
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ ++ + TPL+ A + D + LL GA + TPLH AA
Sbjct: 182 LLANNVNIDHEVPQLGTPLYVACT--YQRVDCVKKLLELGASVDHGQWLD-TPLHAAARQ 238
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ LL DYG ++ R G SAL
Sbjct: 239 SNVEVIHLLTDYGANLKRRNAQGKSAL 265
Score = 48.8 bits (111), Expect = 7e-05
Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 5/156 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + AC G + + LL+ G +L+ + +H + G EC+++LL + +
Sbjct: 133 TPLFNACCSGSAACVNVLLEFGAKA-QLEVHLASPIHEAVKRGHRECMEILLANNVNI-- 189
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D TPL+ A + + + CVK L+ GA V+ G +PLH A EV+ L
Sbjct: 190 -DHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLT 248
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG 241
+ GA ++ L +AA S LLL G
Sbjct: 249 DYGANLKRRNAQGKSALDLAAPKSSVE-QALLLREG 283
>BC103874-1|AAI03875.1| 323|Homo sapiens ankyrin repeat and SOCS
box-containing 11 protein.
Length = 323
Score = 104 bits (250), Expect = 1e-21
Identities = 83/246 (33%), Positives = 114/246 (46%), Gaps = 9/246 (3%)
Query: 63 IGNGNYDETIQFASEAEGG----FGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGR 118
I GN E + A E GG + R+ + A G+ + L L+ GV+ + +
Sbjct: 40 IVKGNRKEAARIAEEIYGGISDCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRV 99
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ LH +CL G C K LL++GAH N T ATPL A + S ACV VL+ GA
Sbjct: 100 SSLHEACLGGHVACAKALLENGAHVN---GVTVHGATPLFNACCSGSAACVNVLLEFGAK 156
Query: 179 VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLL 238
+ SP+H AV E ++ LL D TPL+VA + C K LL
Sbjct: 157 AQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLL 216
Query: 239 NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSL 298
GA V G T LH AA + E LL D+GA++ N +G++ L LA S+
Sbjct: 217 ELGASV--DHGQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSV 274
Query: 299 EVVEML 304
E +L
Sbjct: 275 EQALLL 280
Score = 91.5 bits (217), Expect = 1e-17
Identities = 77/220 (35%), Positives = 109/220 (49%), Gaps = 8/220 (3%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+PLH AA+ L +K LIA G +VN +R S LH A L K LLE GA +
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNG 126
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
V TPL A GSA+C +LL GA +A + A+ +H A + GH EC +LL
Sbjct: 127 VTVHGATPLFNACCSGSAACVNVLLEFGA--KAQLEVHLASPIHEAVKRGHRECMEILLA 184
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTPLHGAIVRGARA 332
+ +ID + TPL++A Q ++ V+ L++ A V + D TPLH A R +
Sbjct: 185 NNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TPLHAA-ARQSNV 241
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
++ LL GA+ + G + L +AA LLL
Sbjct: 242 -EVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLL 280
Score = 75.4 bits (177), Expect = 7e-13
Identities = 51/160 (31%), Positives = 78/160 (48%), Gaps = 4/160 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
+PLH AA+ G K L+ G +V + ++LH A GH CA+ LL++GAH++
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVT-INRVSSLHEACLGGHVACAKALLENGAHVN 125
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
G TPL A + S V +L++ A + + +P+H A+ RG R C L
Sbjct: 126 GVTVHGATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEILLA 184
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ D + G TPL++A + CV LL+ G V
Sbjct: 185 NNVNID-HEVPQLG-TPLYVACTYQRVDCVKKLLELGASV 222
Score = 73.7 bits (173), Expect = 2e-12
Identities = 64/207 (30%), Positives = 88/207 (42%), Gaps = 5/207 (2%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
+DRSPLH A +K L+ G + + + LH A G +C K LL GA
Sbjct: 64 ADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAH 123
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V G AT L A G A C +LL+ GA +P+H A E +E+
Sbjct: 124 VNGVTVHG-ATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEI 181
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ ++ + TPL+ A + D + LL GA + TPLH AA
Sbjct: 182 LLANNVNIDHEVPQLGTPLYVACT--YQRVDCVKKLLELGASVDHGQWLD-TPLHAAARQ 238
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ LL DYG ++ R G SAL
Sbjct: 239 SNVEVIHLLTDYGANLKRRNAQGKSAL 265
Score = 48.8 bits (111), Expect = 7e-05
Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 5/156 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + AC G + + LL+ G +L+ + +H + G EC+++LL + +
Sbjct: 133 TPLFNACCSGSAACVNVLLEFGAKA-QLEVHLASPIHEAVKRGHRECMEILLANNVNI-- 189
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D TPL+ A + + + CVK L+ GA V+ G +PLH A EV+ L
Sbjct: 190 -DHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLT 248
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG 241
+ GA ++ L +AA S LLL G
Sbjct: 249 DYGANLKRRNAQGKSALDLAAPKSSVE-QALLLREG 283
>BC069340-1|AAH69340.1| 323|Homo sapiens ankyrin repeat and SOCS
box-containing protein 11 protein.
Length = 323
Score = 104 bits (250), Expect = 1e-21
Identities = 83/246 (33%), Positives = 114/246 (46%), Gaps = 9/246 (3%)
Query: 63 IGNGNYDETIQFASEAEGG----FGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGR 118
I GN E + A E GG + R+ + A G+ + L L+ GV+ + +
Sbjct: 40 IVKGNRKEAARIAEEIYGGISDCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRV 99
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ LH +CL G C K LL++GAH N T ATPL A + S ACV VL+ GA
Sbjct: 100 SSLHEACLGGHVACAKALLENGAHVN---GVTVHGATPLFNACCSGSAACVNVLLEFGAK 156
Query: 179 VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLL 238
+ SP+H AV E ++ LL D TPL+VA + C K LL
Sbjct: 157 AQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLL 216
Query: 239 NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSL 298
GA V G T LH AA + E LL D+GA++ N +G++ L LA S+
Sbjct: 217 ELGASV--DHGQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSV 274
Query: 299 EVVEML 304
E +L
Sbjct: 275 EQALLL 280
Score = 91.5 bits (217), Expect = 1e-17
Identities = 77/220 (35%), Positives = 109/220 (49%), Gaps = 8/220 (3%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+PLH AA+ L +K LIA G +VN +R S LH A L K LLE GA +
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNG 126
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
V TPL A GSA+C +LL GA +A + A+ +H A + GH EC +LL
Sbjct: 127 VTVHGATPLFNACCSGSAACVNVLLEFGA--KAQLEVHLASPIHEAVKRGHRECMEILLA 184
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTPLHGAIVRGARA 332
+ +ID + TPL++A Q ++ V+ L++ A V + D TPLH A R +
Sbjct: 185 NNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TPLHAA-ARQSNV 241
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
++ LL GA+ + G + L +AA LLL
Sbjct: 242 -EVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLL 280
Score = 75.4 bits (177), Expect = 7e-13
Identities = 51/160 (31%), Positives = 78/160 (48%), Gaps = 4/160 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
+PLH AA+ G K L+ G +V + ++LH A GH CA+ LL++GAH++
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVT-INRVSSLHEACLGGHVACAKALLENGAHVN 125
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
G TPL A + S V +L++ A + + +P+H A+ RG R C L
Sbjct: 126 GVTVHGATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEILLA 184
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ D + G TPL++A + CV LL+ G V
Sbjct: 185 NNVNID-HEVPQLG-TPLYVACTYQRVDCVKKLLELGASV 222
Score = 73.7 bits (173), Expect = 2e-12
Identities = 64/207 (30%), Positives = 88/207 (42%), Gaps = 5/207 (2%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
+DRSPLH A +K L+ G + + + LH A G +C K LL GA
Sbjct: 64 ADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAH 123
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V G AT L A G A C +LL+ GA +P+H A E +E+
Sbjct: 124 VNGVTVHG-ATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEI 181
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ ++ + TPL+ A + D + LL GA + TPLH AA
Sbjct: 182 LLANNVNIDHEVPQLGTPLYVACT--YQRVDCVKKLLELGASVDHGQWLD-TPLHAAARQ 238
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ LL DYG ++ R G SAL
Sbjct: 239 SNVEVIHLLTDYGANLKRRNAQGKSAL 265
Score = 48.8 bits (111), Expect = 7e-05
Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 5/156 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + AC G + + LL+ G +L+ + +H + G EC+++LL + +
Sbjct: 133 TPLFNACCSGSAACVNVLLEFGAKA-QLEVHLASPIHEAVKRGHRECMEILLANNVNI-- 189
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D TPL+ A + + + CVK L+ GA V+ G +PLH A EV+ L
Sbjct: 190 -DHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLT 248
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG 241
+ GA ++ L +AA S LLL G
Sbjct: 249 DYGANLKRRNAQGKSALDLAAPKSSVE-QALLLREG 283
>AF425642-1|AAL60519.1| 323|Homo sapiens ankyrin repeat
domain-containing SOCS box protein ASB11 protein.
Length = 323
Score = 104 bits (250), Expect = 1e-21
Identities = 83/246 (33%), Positives = 114/246 (46%), Gaps = 9/246 (3%)
Query: 63 IGNGNYDETIQFASEAEGG----FGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGR 118
I GN E + A E GG + R+ + A G+ + L L+ GV+ + +
Sbjct: 40 IVKGNRKEAARIAEEIYGGISDCWADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRV 99
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ LH +CL G C K LL++GAH N T ATPL A + S ACV VL+ GA
Sbjct: 100 SSLHEACLGGHVACAKALLENGAHVN---GVTVHGATPLFNACCSGSAACVNVLLEFGAK 156
Query: 179 VNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLL 238
+ SP+H AV E ++ LL D TPL+VA + C K LL
Sbjct: 157 AQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLL 216
Query: 239 NAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSL 298
GA V G T LH AA + E LL D+GA++ N +G++ L LA S+
Sbjct: 217 ELGASV--DHGQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSSV 274
Query: 299 EVVEML 304
E +L
Sbjct: 275 EQALLL 280
Score = 91.5 bits (217), Expect = 1e-17
Identities = 77/220 (35%), Positives = 109/220 (49%), Gaps = 8/220 (3%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+PLH AA+ L +K LIA G +VN +R S LH A L K LLE GA +
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVNG 126
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
V TPL A GSA+C +LL GA +A + A+ +H A + GH EC +LL
Sbjct: 127 VTVHGATPLFNACCSGSAACVNVLLEFGA--KAQLEVHLASPIHEAVKRGHRECMEILLA 184
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTPLHGAIVRGARA 332
+ +ID + TPL++A Q ++ V+ L++ A V + D TPLH A R +
Sbjct: 185 NNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TPLHAA-ARQSNV 241
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
++ LL GA+ + G + L +AA LLL
Sbjct: 242 -EVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLL 280
Score = 75.4 bits (177), Expect = 7e-13
Identities = 51/160 (31%), Positives = 78/160 (48%), Gaps = 4/160 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
+PLH AA+ G K L+ G +V + ++LH A GH CA+ LL++GAH++
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQGVNVNLVT-INRVSSLHEACLGGHVACAKALLENGAHVN 125
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
G TPL A + S V +L++ A + + +P+H A+ RG R C L
Sbjct: 126 GVTVHGATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEILLA 184
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ D + G TPL++A + CV LL+ G V
Sbjct: 185 NNVNID-HEVPQLG-TPLYVACTYQRVDCVKKLLELGASV 222
Score = 73.7 bits (173), Expect = 2e-12
Identities = 64/207 (30%), Positives = 88/207 (42%), Gaps = 5/207 (2%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
+DRSPLH A +K L+ G + + + LH A G +C K LL GA
Sbjct: 64 ADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAH 123
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V G AT L A G A C +LL+ GA +P+H A E +E+
Sbjct: 124 VNGVTVHG-ATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEI 181
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ ++ + TPL+ A + D + LL GA + TPLH AA
Sbjct: 182 LLANNVNIDHEVPQLGTPLYVACT--YQRVDCVKKLLELGASVDHGQWLD-TPLHAAARQ 238
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ LL DYG ++ R G SAL
Sbjct: 239 SNVEVIHLLTDYGANLKRRNAQGKSAL 265
Score = 48.8 bits (111), Expect = 7e-05
Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 5/156 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + AC G + + LL+ G +L+ + +H + G EC+++LL + +
Sbjct: 133 TPLFNACCSGSAACVNVLLEFGAKA-QLEVHLASPIHEAVKRGHRECMEILLANNVNI-- 189
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D TPL+ A + + + CVK L+ GA V+ G +PLH A EV+ L
Sbjct: 190 -DHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLT 248
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG 241
+ GA ++ L +AA S LLL G
Sbjct: 249 DYGANLKRRNAQGKSALDLAAPKSSVE-QALLLREG 283
>BC075088-1|AAH75088.1| 453|Homo sapiens ankyrin repeat and SOCS
box-containing protein 16 protein.
Length = 453
Score = 103 bits (246), Expect = 3e-21
Identities = 78/239 (32%), Positives = 107/239 (44%), Gaps = 11/239 (4%)
Query: 131 ECVKLLLDHGAHPNTWDSSTETKAT-PLHCAASAKSLACVKVLIAHGADVNAGLSDRSPL 189
E V L A W + +TK T PL A + C + LI GA+++A + R+ L
Sbjct: 88 ETVSNQLAWSAEQGFWVLTPKTKQTAPLAIATARGYTDCARHLIRQGAELDARVGGRAAL 147
Query: 190 HYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
H A + V+ LL GA + TPLH+ S C KLLL AGA V A G
Sbjct: 148 HEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAG 207
Query: 250 PGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA--------TLAQSLEVV 301
+ T LH+AA G + L L+HGA + +G+T L+ A + +
Sbjct: 208 ESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAA 267
Query: 302 EMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L++ AD RA TPLH A G +A LLL GA + G+TP+ A
Sbjct: 268 RRLLEAGADARAAGRKRHTPLHNACASGCGG--LAELLLRYGARAEVPNGAGHTPMDCA 324
Score = 85.4 bits (202), Expect = 7e-16
Identities = 68/220 (30%), Positives = 96/220 (43%), Gaps = 9/220 (4%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PL A + + L+ GA D +V LH A + C +LLL GA
Sbjct: 113 APLAIATARGYTDCARHLIRQGAELDA-RVGGRAALHEACARAQFDCVRLLLTFGAKANV 171
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLV 305
G T LHL +CA+LLL+ GA ++ Q TPLH+A + V + +
Sbjct: 172 LTEEG-TTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYL 230
Query: 306 DRCADVRAKDADGRTPLHGAIV--RGARACD----IARLLLSAGADPNAADNFGYTPLHI 359
+ ADV + + G T L+ A G +C AR LL AGAD AA +TPLH
Sbjct: 231 EHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHN 290
Query: 360 AALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
A + LLL YG + G + + ++ V D
Sbjct: 291 ACASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQD 330
Score = 72.5 bits (170), Expect = 5e-12
Identities = 75/245 (30%), Positives = 104/245 (42%), Gaps = 21/245 (8%)
Query: 72 IQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEE 131
I+ +E + G R A+ AC + + LL G + L + G T LHL + S +
Sbjct: 131 IRQGAELDARVGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQ 190
Query: 132 CVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHY 191
C KLLL+ GA N ++ E++ TPLH AA+ V + + HGADV S
Sbjct: 191 CAKLLLEAGATVNL--AAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALN 248
Query: 192 AVLSDA---------PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
A + A + LLEAGA TPLH A + G +LLL GA
Sbjct: 249 AACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGA 308
Query: 243 DVRAAMGPGKA---TALHLAAEDGHAECARL---LLDHGAHIDWPNFRGQTPLHLATLAQ 296
G G AL + + E L LLD+GA R + H A +
Sbjct: 309 RAEVPNGAGHTPMDCALQAVQDAPNWEPEVLFAALLDYGAQ----PVRPEMLKHCANFPR 364
Query: 297 SLEVV 301
+LEV+
Sbjct: 365 ALEVL 369
Score = 54.0 bits (124), Expect = 2e-06
Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+ G + P + PL +AT + L+ + A++ A+ GR LH A R
Sbjct: 99 EQGFWVLTPKTKQTAPLAIATARGYTDCARHLIRQGAELDAR-VGGRAALHEACARAQFD 157
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
C RLLL+ GA N G TPLH+ + E C LLL+ G V L
Sbjct: 158 C--VRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNL 204
>AK054727-1|BAB70800.1| 453|Homo sapiens protein ( Homo sapiens
cDNA FLJ30165 fis, clone BRACE2000698, weakly similar to
ANKYRIN 2. ).
Length = 453
Score = 103 bits (246), Expect = 3e-21
Identities = 78/239 (32%), Positives = 107/239 (44%), Gaps = 11/239 (4%)
Query: 131 ECVKLLLDHGAHPNTWDSSTETKAT-PLHCAASAKSLACVKVLIAHGADVNAGLSDRSPL 189
E V L A W + +TK T PL A + C + LI GA+++A + R+ L
Sbjct: 88 ETVSNQLAWSAEQGFWVLTPKTKQTAPLAIATARGYTDCARHLIRQGAELDARVGGRAAL 147
Query: 190 HYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
H A + V+ LL GA + TPLH+ S C KLLL AGA V A G
Sbjct: 148 HEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAG 207
Query: 250 PGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLA--------TLAQSLEVV 301
+ T LH+AA G + L L+HGA + +G+T L+ A + +
Sbjct: 208 ESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAA 267
Query: 302 EMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
L++ AD RA TPLH A G +A LLL GA + G+TP+ A
Sbjct: 268 RRLLEAGADARAAGRKRHTPLHNACASGCGG--LAELLLRYGARAEVPNGAGHTPMDCA 324
Score = 85.4 bits (202), Expect = 7e-16
Identities = 68/220 (30%), Positives = 96/220 (43%), Gaps = 9/220 (4%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PL A + + L+ GA D +V LH A + C +LLL GA
Sbjct: 113 APLAIATARGYTDCARHLIRQGAELDA-RVGGRAALHEACARAQFDCVRLLLTFGAKANV 171
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLV 305
G T LHL +CA+LLL+ GA ++ Q TPLH+A + V + +
Sbjct: 172 LTEEG-TTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYL 230
Query: 306 DRCADVRAKDADGRTPLHGAIV--RGARACD----IARLLLSAGADPNAADNFGYTPLHI 359
+ ADV + + G T L+ A G +C AR LL AGAD AA +TPLH
Sbjct: 231 EHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHN 290
Query: 360 AALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
A + LLL YG + G + + ++ V D
Sbjct: 291 ACASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQD 330
Score = 72.5 bits (170), Expect = 5e-12
Identities = 75/245 (30%), Positives = 104/245 (42%), Gaps = 21/245 (8%)
Query: 72 IQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEE 131
I+ +E + G R A+ AC + + LL G + L + G T LHL + S +
Sbjct: 131 IRQGAELDARVGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQ 190
Query: 132 CVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHY 191
C KLLL+ GA N ++ E++ TPLH AA+ V + + HGADV S
Sbjct: 191 CAKLLLEAGATVNL--AAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALN 248
Query: 192 AVLSDA---------PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
A + A + LLEAGA TPLH A + G +LLL GA
Sbjct: 249 AACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGA 308
Query: 243 DVRAAMGPGKA---TALHLAAEDGHAECARL---LLDHGAHIDWPNFRGQTPLHLATLAQ 296
G G AL + + E L LLD+GA R + H A +
Sbjct: 309 RAEVPNGAGHTPMDCALQAVQDAPNWEPEVLFAALLDYGAQ----PVRPEMLKHCANFPR 364
Query: 297 SLEVV 301
+LEV+
Sbjct: 365 ALEVL 369
Score = 54.0 bits (124), Expect = 2e-06
Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 3/109 (2%)
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+ G + P + PL +AT + L+ + A++ A+ GR LH A R
Sbjct: 99 EQGFWVLTPKTKQTAPLAIATARGYTDCARHLIRQGAELDAR-VGGRAALHEACARAQFD 157
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
C RLLL+ GA N G TPLH+ + E C LLL+ G V L
Sbjct: 158 C--VRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNL 204
>BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 102 bits (244), Expect = 5e-21
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 11/250 (4%)
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
AG T + + G + +KLLL D + +H AA A ++VL
Sbjct: 463 AGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRA---VHHAAFGDEGAVIEVLHRG 519
Query: 176 GADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
AD+NA R +PLH AV +VVK LL+ G P +TPLH A S
Sbjct: 520 SADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDIL 579
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH---IDWPNFRGQTPLHL 291
+LL AGADV G ALH AA G+ R+LL +D G T LHL
Sbjct: 580 AVLLEAGADVTITNNNG-FNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHL 638
Query: 292 ATLAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A L +EV E+LV + A++ ++ + +T LH A+ R + I RLL+ AGA + D
Sbjct: 639 AALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER--QHTQIVRLLVRAGAKLDIQD 696
Query: 351 NFGYTPLHIA 360
G TPLH A
Sbjct: 697 KDGDTPLHEA 706
Score = 98.7 bits (235), Expect = 7e-20
Identities = 94/294 (31%), Positives = 135/294 (45%), Gaps = 16/294 (5%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
EAE G R A+ A + + ++ L + D + + +T LH++ G + VK L
Sbjct: 491 EAEDKDGDR-AVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTL 549
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLS 195
LD G HP+ DS +T PLH A S K + VL+ GADV ++ + LH+A L
Sbjct: 550 LDFGCHPSLQDSEGDT---PLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALR 606
Query: 196 DAPEVVKELLEAGACP---DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
P ++ LL P D + T LH+AA +LL++ G +
Sbjct: 607 GNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQ 666
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
TALHLA E H + RLL+ GA +D + G TPLH A +L + L D DV
Sbjct: 667 QTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQD-MQDVG 725
Query: 313 AKDA----DGRTPLHGAIVRGAR---ACDIARLLLSAGADPNAADNFGYTPLHI 359
DA T + G +GA A IA L + GAD + + G +PL +
Sbjct: 726 KVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDL 779
Score = 83.0 bits (196), Expect = 3e-15
Identities = 73/267 (27%), Positives = 122/267 (45%), Gaps = 9/267 (3%)
Query: 160 AASAKSLACVKVLIAH-GADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA+ +A V+ L+ DVN + + + A + +++K LL+ +
Sbjct: 438 AAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDG 497
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
+ +H AA + ++L AD+ A + T LH+A GH + + LLD G H
Sbjct: 498 DRAVHHAAFGDEGAVIEVLHRGSADLNAR-NKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ G TPLH A + +++ +L++ ADV + +G LH A +RG + R+
Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSA--MRV 614
Query: 339 LLSAGADPNAAD---NFGYTPLHIAALNEFSACVLLLLDYG-GDVTLRTNGGVSALSFIV 394
LLS P D + GYT LH+AALN LL+ G ++ ++ +AL V
Sbjct: 615 LLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAV 674
Query: 395 RRVPDVIPRYLCKFDDAVHVSEHELGD 421
R I R L + + + + + GD
Sbjct: 675 ERQHTQIVRLLVRAGAKLDIQDKD-GD 700
>BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 102 bits (244), Expect = 5e-21
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 11/250 (4%)
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
AG T + + G + +KLLL D + +H AA A ++VL
Sbjct: 463 AGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRA---VHHAAFGDEGAVIEVLHRG 519
Query: 176 GADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
AD+NA R +PLH AV +VVK LL+ G P +TPLH A S
Sbjct: 520 SADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDIL 579
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH---IDWPNFRGQTPLHL 291
+LL AGADV G ALH AA G+ R+LL +D G T LHL
Sbjct: 580 AVLLEAGADVTITNNNG-FNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHL 638
Query: 292 ATLAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A L +EV E+LV + A++ ++ + +T LH A+ R + I RLL+ AGA + D
Sbjct: 639 AALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER--QHTQIVRLLVRAGAKLDIQD 696
Query: 351 NFGYTPLHIA 360
G TPLH A
Sbjct: 697 KDGDTPLHEA 706
Score = 98.7 bits (235), Expect = 7e-20
Identities = 94/294 (31%), Positives = 135/294 (45%), Gaps = 16/294 (5%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
EAE G R A+ A + + ++ L + D + + +T LH++ G + VK L
Sbjct: 491 EAEDKDGDR-AVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTL 549
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLS 195
LD G HP+ DS +T PLH A S K + VL+ GADV ++ + LH+A L
Sbjct: 550 LDFGCHPSLQDSEGDT---PLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALR 606
Query: 196 DAPEVVKELLEAGACP---DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
P ++ LL P D + T LH+AA +LL++ G +
Sbjct: 607 GNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQ 666
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
TALHLA E H + RLL+ GA +D + G TPLH A +L + L D DV
Sbjct: 667 QTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQD-MQDVG 725
Query: 313 AKDA----DGRTPLHGAIVRGAR---ACDIARLLLSAGADPNAADNFGYTPLHI 359
DA T + G +GA A IA L + GAD + + G +PL +
Sbjct: 726 KVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDL 779
Score = 83.0 bits (196), Expect = 3e-15
Identities = 73/267 (27%), Positives = 122/267 (45%), Gaps = 9/267 (3%)
Query: 160 AASAKSLACVKVLIAH-GADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA+ +A V+ L+ DVN + + + A + +++K LL+ +
Sbjct: 438 AAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDG 497
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
+ +H AA + ++L AD+ A + T LH+A GH + + LLD G H
Sbjct: 498 DRAVHHAAFGDEGAVIEVLHRGSADLNAR-NKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ G TPLH A + +++ +L++ ADV + +G LH A +RG + R+
Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSA--MRV 614
Query: 339 LLSAGADPNAAD---NFGYTPLHIAALNEFSACVLLLLDYG-GDVTLRTNGGVSALSFIV 394
LLS P D + GYT LH+AALN LL+ G ++ ++ +AL V
Sbjct: 615 LLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAV 674
Query: 395 RRVPDVIPRYLCKFDDAVHVSEHELGD 421
R I R L + + + + + GD
Sbjct: 675 ERQHTQIVRLLVRAGAKLDIQDKD-GD 700
>BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein.
Length = 420
Score = 102 bits (244), Expect = 5e-21
Identities = 82/278 (29%), Positives = 131/278 (47%), Gaps = 9/278 (3%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L LS G +++L++ GA + ++ T LHCAA + + ++ DV
Sbjct: 1 LLLSAWFGHLRILQILVNSGAKIHC---ESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA 57
Query: 181 AGLSD---RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
D R+ H A + + L+ +G + T LH+AA G + + L
Sbjct: 58 LDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRL 117
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
++ G D+ G TALH AA H +C +LLL G+ ++ + + LH A L+ S
Sbjct: 118 VDIGLDLEEQNAEG-LTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGS 176
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V +L+ D G +PLH A+ A + RLL+++ +D NA DN TPL
Sbjct: 177 EDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPA--LVRLLINSDSDVNAVDNRQQTPL 234
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
H+AA + + +LL G D+ LR G +AL+ VR
Sbjct: 235 HLAAEHAWQDIADMLLIAGVDLNLRDEQGKTALAVAVR 272
Score = 96.3 bits (229), Expect = 4e-19
Identities = 70/222 (31%), Positives = 111/222 (50%), Gaps = 5/222 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA A G+ L L+ G D + D G T LHL+ G ++ L+D G
Sbjct: 66 RTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLD-- 123
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T LH AA CV++L+ G+ VNA + S LHYA LS + +V +
Sbjct: 124 -LEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 182
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
L+ AG C + +PLH+A + +LL+N+ +DV A + + T LHLAAE
Sbjct: 183 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNA-VDNRQQTPLHLAAEHA 241
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
+ A +LL G ++ + +G+T L +A + + +V+M++
Sbjct: 242 WQDIADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMII 283
Score = 95.1 bits (226), Expect = 8e-19
Identities = 80/287 (27%), Positives = 125/287 (43%), Gaps = 5/287 (1%)
Query: 88 ILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWD 147
+L + W G +L L+ G G T LH + G + +++ D
Sbjct: 1 LLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMED-LEDVALD 59
Query: 148 SSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLE 206
+ T H AA L + L+ G D N + + LH A V++ L++
Sbjct: 60 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVD 119
Query: 207 AGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAE 266
G + T LH AA C +LLL AG+ V A + + LH AA G +
Sbjct: 120 IGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNA-LTQKNLSCLHYAALSGSED 178
Query: 267 CARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAI 326
+R+L+ G + + +G +PLHLA +V +L++ +DV A D +TPLH A
Sbjct: 179 VSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAA 238
Query: 327 VRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ DIA +LL AG D N D G T L +A + + V +++
Sbjct: 239 EHAWQ--DIADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMII 283
Score = 76.2 bits (179), Expect = 4e-13
Identities = 63/227 (27%), Positives = 98/227 (43%), Gaps = 8/227 (3%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD--HGAHID 279
L ++A G ++L+N+GA + G T LH AA+ GH +++ +D
Sbjct: 1 LLLSAWFGHLRILQILVNSGAKIHCESKDG-LTLLHCAAQKGHVPVLAFIMEDLEDVALD 59
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
+ G+T H A L+ ++ LV D KD +G T LH A RG A + + L
Sbjct: 60 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMA--VLQRL 117
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
+ G D + G T LH AA CV LLL G V T +S L + +
Sbjct: 118 VDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSE 177
Query: 400 VIPRYLCKFDDAVHVSEHELGDVDCELTI--DFRPLVPCLTRGEAEL 444
+ R L +V +H+ G L + +F LV L ++++
Sbjct: 178 DVSRVLIHAGGCANVVDHQ-GASPLHLAVRHNFPALVRLLINSDSDV 223
Score = 75.4 bits (177), Expect = 7e-13
Identities = 59/196 (30%), Positives = 92/196 (46%), Gaps = 5/196 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G +L +L+ +G+D +E + G T LH + +CV+LLL G +T
Sbjct: 100 TALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAG---ST 156
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
++ T+ + LH AA + S +VLI G N SPLH AV + P +V+ L
Sbjct: 157 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 216
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
+ + + + +TPLH+AA +LL AG D+ GK TAL +A H
Sbjct: 217 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDEQGK-TALAVAVRSNH 275
Query: 265 AECARLLLDHGAHIDW 280
+++ W
Sbjct: 276 VSLVDMIIKADRFYRW 291
Score = 72.9 bits (171), Expect = 4e-12
Identities = 60/199 (30%), Positives = 86/199 (43%), Gaps = 3/199 (1%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAA-MGPGKATALHLAAEDGHAECARLLLDHGAHI 278
T LH AA G ++ DV + TA H AAE G + L+ G
Sbjct: 32 TLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDH 91
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ + G T LHLA + V++ LVD D+ ++A+G T LH A G D +L
Sbjct: 92 NVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAA--GGSHPDCVQL 149
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL AG+ NA + LH AAL+ +L+ GG + + G S L VR
Sbjct: 150 LLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNF 209
Query: 399 DVIPRYLCKFDDAVHVSEH 417
+ R L D V+ ++
Sbjct: 210 PALVRLLINSDSDVNAVDN 228
>BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 102 bits (244), Expect = 5e-21
Identities = 82/278 (29%), Positives = 131/278 (47%), Gaps = 9/278 (3%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L LS G +++L++ GA + ++ T LHCAA + + ++ DV
Sbjct: 4 LLLSAWFGHLRILQILVNSGAKIHC---ESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA 60
Query: 181 AGLSD---RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
D R+ H A + + L+ +G + T LH+AA G + + L
Sbjct: 61 LDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRL 120
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
++ G D+ G TALH AA H +C +LLL G+ ++ + + LH A L+ S
Sbjct: 121 VDIGLDLEEQNAEG-LTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGS 179
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V +L+ D G +PLH A+ A + RLL+++ +D NA DN TPL
Sbjct: 180 EDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPA--LVRLLINSDSDVNAVDNRQQTPL 237
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
H+AA + + +LL G D+ LR G +AL+ VR
Sbjct: 238 HLAAEHAWQDIADMLLIAGVDLNLRDKQGKTALAVAVR 275
Score = 96.7 bits (230), Expect = 3e-19
Identities = 81/288 (28%), Positives = 126/288 (43%), Gaps = 5/288 (1%)
Query: 87 AILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTW 146
A+L + W G +L L+ G G T LH + G + +++
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMED-LEDVAL 61
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELL 205
D + T H AA L + L+ G D N + + LH A V++ L+
Sbjct: 62 DHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLV 121
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ G + T LH AA C +LLL AG+ V A + + LH AA G
Sbjct: 122 DIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNA-LTQKNLSCLHYAALSGSE 180
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +R+L+ G + + +G +PLHLA +V +L++ +DV A D +TPLH A
Sbjct: 181 DVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLA 240
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ DIA +LL AG D N D G T L +A + + V +++
Sbjct: 241 AEHAWQ--DIADMLLIAGVDLNLRDKQGKTALAVAVRSNHVSLVDMII 286
Score = 96.3 bits (229), Expect = 4e-19
Identities = 70/222 (31%), Positives = 111/222 (50%), Gaps = 5/222 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA A G+ L L+ G D + D G T LHL+ G ++ L+D G
Sbjct: 69 RTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLD-- 126
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T LH AA CV++L+ G+ VNA + S LHYA LS + +V +
Sbjct: 127 -LEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
L+ AG C + +PLH+A + +LL+N+ +DV A + + T LHLAAE
Sbjct: 186 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNA-VDNRQQTPLHLAAEHA 244
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
+ A +LL G ++ + +G+T L +A + + +V+M++
Sbjct: 245 WQDIADMLLIAGVDLNLRDKQGKTALAVAVRSNHVSLVDMII 286
Score = 76.2 bits (179), Expect = 4e-13
Identities = 63/227 (27%), Positives = 98/227 (43%), Gaps = 8/227 (3%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD--HGAHID 279
L ++A G ++L+N+GA + G T LH AA+ GH +++ +D
Sbjct: 4 LLLSAWFGHLRILQILVNSGAKIHCESKDG-LTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
+ G+T H A L+ ++ LV D KD +G T LH A RG A + + L
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMA--VLQRL 120
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
+ G D + G T LH AA CV LLL G V T +S L + +
Sbjct: 121 VDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSE 180
Query: 400 VIPRYLCKFDDAVHVSEHELGDVDCELTI--DFRPLVPCLTRGEAEL 444
+ R L +V +H+ G L + +F LV L ++++
Sbjct: 181 DVSRVLIHAGGCANVVDHQ-GASPLHLAVRHNFPALVRLLINSDSDV 226
Score = 75.4 bits (177), Expect = 7e-13
Identities = 59/196 (30%), Positives = 92/196 (46%), Gaps = 5/196 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G +L +L+ +G+D +E + G T LH + +CV+LLL G +T
Sbjct: 103 TALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAG---ST 159
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
++ T+ + LH AA + S +VLI G N SPLH AV + P +V+ L
Sbjct: 160 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
+ + + + +TPLH+AA +LL AG D+ GK TAL +A H
Sbjct: 220 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGK-TALAVAVRSNH 278
Query: 265 AECARLLLDHGAHIDW 280
+++ W
Sbjct: 279 VSLVDMIIKADRFYRW 294
Score = 72.9 bits (171), Expect = 4e-12
Identities = 60/199 (30%), Positives = 86/199 (43%), Gaps = 3/199 (1%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAA-MGPGKATALHLAAEDGHAECARLLLDHGAHI 278
T LH AA G ++ DV + TA H AAE G + L+ G
Sbjct: 35 TLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDH 94
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ + G T LHLA + V++ LVD D+ ++A+G T LH A G D +L
Sbjct: 95 NVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAA--GGSHPDCVQL 152
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL AG+ NA + LH AAL+ +L+ GG + + G S L VR
Sbjct: 153 LLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNF 212
Query: 399 DVIPRYLCKFDDAVHVSEH 417
+ R L D V+ ++
Sbjct: 213 PALVRLLINSDSDVNAVDN 231
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/138 (32%), Positives = 65/138 (47%), Gaps = 4/138 (2%)
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
AL L+A GH ++L++ GA I + G T LH A + V+ +++ DV
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 315 DAD--GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D GRT H A G D L+ +G D N D G T LH+AA A + L
Sbjct: 63 HVDKLGRTAFHRAAEHG--QLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRL 120
Query: 373 LDYGGDVTLRTNGGVSAL 390
+D G D+ + G++AL
Sbjct: 121 VDIGLDLEEQNAEGLTAL 138
>BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 102 bits (244), Expect = 5e-21
Identities = 82/278 (29%), Positives = 131/278 (47%), Gaps = 9/278 (3%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L LS G +++L++ GA + ++ T LHCAA + + ++ DV
Sbjct: 4 LLLSAWFGHLRILQILVNSGAKIHC---ESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA 60
Query: 181 AGLSD---RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
D R+ H A + + L+ +G + T LH+AA G + + L
Sbjct: 61 LDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRL 120
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
++ G D+ G TALH AA H +C +LLL G+ ++ + + LH A L+ S
Sbjct: 121 VDIGLDLEEQNAEG-LTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGS 179
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V +L+ D G +PLH A+ A + RLL+++ +D NA DN TPL
Sbjct: 180 EDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPA--LVRLLINSDSDVNAVDNRQQTPL 237
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
H+AA + + +LL G D+ LR G +AL+ VR
Sbjct: 238 HLAAEHAWQDIADMLLIAGVDLNLRDEQGKTALAVAVR 275
Score = 96.7 bits (230), Expect = 3e-19
Identities = 81/288 (28%), Positives = 126/288 (43%), Gaps = 5/288 (1%)
Query: 87 AILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTW 146
A+L + W G +L L+ G G T LH + G + +++
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMED-LEDVAL 61
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELL 205
D + T H AA L + L+ G D N + + LH A V++ L+
Sbjct: 62 DHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLV 121
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ G + T LH AA C +LLL AG+ V A + + LH AA G
Sbjct: 122 DIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNA-LTQKNLSCLHYAALSGSE 180
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +R+L+ G + + +G +PLHLA +V +L++ +DV A D +TPLH A
Sbjct: 181 DVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLA 240
Query: 326 IVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ DIA +LL AG D N D G T L +A + + V +++
Sbjct: 241 AEHAWQ--DIADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMII 286
Score = 96.3 bits (229), Expect = 4e-19
Identities = 70/222 (31%), Positives = 111/222 (50%), Gaps = 5/222 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA A G+ L L+ G D + D G T LHL+ G ++ L+D G
Sbjct: 69 RTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLD-- 126
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T LH AA CV++L+ G+ VNA + S LHYA LS + +V +
Sbjct: 127 -LEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
L+ AG C + +PLH+A + +LL+N+ +DV A + + T LHLAAE
Sbjct: 186 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNA-VDNRQQTPLHLAAEHA 244
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
+ A +LL G ++ + +G+T L +A + + +V+M++
Sbjct: 245 WQDIADMLLIAGVDLNLRDEQGKTALAVAVRSNHVSLVDMII 286
Score = 76.2 bits (179), Expect = 4e-13
Identities = 63/227 (27%), Positives = 98/227 (43%), Gaps = 8/227 (3%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD--HGAHID 279
L ++A G ++L+N+GA + G T LH AA+ GH +++ +D
Sbjct: 4 LLLSAWFGHLRILQILVNSGAKIHCESKDG-LTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
+ G+T H A L+ ++ LV D KD +G T LH A RG A + + L
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMA--VLQRL 120
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
+ G D + G T LH AA CV LLL G V T +S L + +
Sbjct: 121 VDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSE 180
Query: 400 VIPRYLCKFDDAVHVSEHELGDVDCELTI--DFRPLVPCLTRGEAEL 444
+ R L +V +H+ G L + +F LV L ++++
Sbjct: 181 DVSRVLIHAGGCANVVDHQ-GASPLHLAVRHNFPALVRLLINSDSDV 226
Score = 75.4 bits (177), Expect = 7e-13
Identities = 59/196 (30%), Positives = 92/196 (46%), Gaps = 5/196 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G +L +L+ +G+D +E + G T LH + +CV+LLL G +T
Sbjct: 103 TALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAG---ST 159
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
++ T+ + LH AA + S +VLI G N SPLH AV + P +V+ L
Sbjct: 160 VNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLL 219
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
+ + + + +TPLH+AA +LL AG D+ GK TAL +A H
Sbjct: 220 INSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDEQGK-TALAVAVRSNH 278
Query: 265 AECARLLLDHGAHIDW 280
+++ W
Sbjct: 279 VSLVDMIIKADRFYRW 294
Score = 72.9 bits (171), Expect = 4e-12
Identities = 60/199 (30%), Positives = 86/199 (43%), Gaps = 3/199 (1%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAA-MGPGKATALHLAAEDGHAECARLLLDHGAHI 278
T LH AA G ++ DV + TA H AAE G + L+ G
Sbjct: 35 TLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDH 94
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ + G T LHLA + V++ LVD D+ ++A+G T LH A G D +L
Sbjct: 95 NVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAA--GGSHPDCVQL 152
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL AG+ NA + LH AAL+ +L+ GG + + G S L VR
Sbjct: 153 LLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNF 212
Query: 399 DVIPRYLCKFDDAVHVSEH 417
+ R L D V+ ++
Sbjct: 213 PALVRLLINSDSDVNAVDN 231
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/138 (32%), Positives = 65/138 (47%), Gaps = 4/138 (2%)
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
AL L+A GH ++L++ GA I + G T LH A + V+ +++ DV
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 315 DAD--GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
D GRT H A G D L+ +G D N D G T LH+AA A + L
Sbjct: 63 HVDKLGRTAFHRAAEHG--QLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRL 120
Query: 373 LDYGGDVTLRTNGGVSAL 390
+D G D+ + G++AL
Sbjct: 121 VDIGLDLEEQNAEGLTAL 138
>AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein.
Length = 1006
Score = 102 bits (244), Expect = 5e-21
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 11/250 (4%)
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
AG T + + G + +KLLL D + +H AA A ++VL
Sbjct: 463 AGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRA---VHHAAFGDEGAVIEVLHRG 519
Query: 176 GADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
AD+NA R +PLH AV +VVK LL+ G P +TPLH A S
Sbjct: 520 SADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDIL 579
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH---IDWPNFRGQTPLHL 291
+LL AGADV G ALH AA G+ R+LL +D G T LHL
Sbjct: 580 AVLLEAGADVTITNNNG-FNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHL 638
Query: 292 ATLAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A L +EV E+LV + A++ ++ + +T LH A+ R + I RLL+ AGA + D
Sbjct: 639 AALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER--QHTQIVRLLVRAGAKLDIQD 696
Query: 351 NFGYTPLHIA 360
G TPLH A
Sbjct: 697 KDGDTPLHEA 706
Score = 98.7 bits (235), Expect = 7e-20
Identities = 94/294 (31%), Positives = 135/294 (45%), Gaps = 16/294 (5%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
EAE G R A+ A + + ++ L + D + + +T LH++ G + VK L
Sbjct: 491 EAEDKDGDR-AVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTL 549
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLS 195
LD G HP+ DS +T PLH A S K + VL+ GADV ++ + LH+A L
Sbjct: 550 LDFGCHPSLQDSEGDT---PLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALR 606
Query: 196 DAPEVVKELLEAGACP---DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
P ++ LL P D + T LH+AA +LL++ G +
Sbjct: 607 GNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQ 666
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
TALHLA E H + RLL+ GA +D + G TPLH A +L + L D DV
Sbjct: 667 QTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQD-MQDVG 725
Query: 313 AKDA----DGRTPLHGAIVRGAR---ACDIARLLLSAGADPNAADNFGYTPLHI 359
DA T + G +GA A IA L + GAD + + G +PL +
Sbjct: 726 KVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDL 779
Score = 83.0 bits (196), Expect = 3e-15
Identities = 73/267 (27%), Positives = 122/267 (45%), Gaps = 9/267 (3%)
Query: 160 AASAKSLACVKVLIAH-GADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA+ +A V+ L+ DVN + + + A + +++K LL+ +
Sbjct: 438 AAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDG 497
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
+ +H AA + ++L AD+ A + T LH+A GH + + LLD G H
Sbjct: 498 DRAVHHAAFGDEGAVIEVLHRGSADLNAR-NKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 556
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ G TPLH A + +++ +L++ ADV + +G LH A +RG + R+
Sbjct: 557 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSA--MRV 614
Query: 339 LLSAGADPNAAD---NFGYTPLHIAALNEFSACVLLLLDYG-GDVTLRTNGGVSALSFIV 394
LLS P D + GYT LH+AALN LL+ G ++ ++ +AL V
Sbjct: 615 LLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAV 674
Query: 395 RRVPDVIPRYLCKFDDAVHVSEHELGD 421
R I R L + + + + + GD
Sbjct: 675 ERQHTQIVRLLVRAGAKLDIQDKD-GD 700
>AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein.
Length = 997
Score = 102 bits (244), Expect = 5e-21
Identities = 88/250 (35%), Positives = 118/250 (47%), Gaps = 11/250 (4%)
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
AG T + + G + +KLLL D + +H AA A ++VL
Sbjct: 454 AGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRA---VHHAAFGDEGAVIEVLHRG 510
Query: 176 GADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
AD+NA R +PLH AV +VVK LL+ G P +TPLH A S
Sbjct: 511 SADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDIL 570
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH---IDWPNFRGQTPLHL 291
+LL AGADV G ALH AA G+ R+LL +D G T LHL
Sbjct: 571 AVLLEAGADVTITNNNG-FNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHL 629
Query: 292 ATLAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAAD 350
A L +EV E+LV + A++ ++ + +T LH A+ R + I RLL+ AGA + D
Sbjct: 630 AALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER--QHTQIVRLLVRAGAKLDIQD 687
Query: 351 NFGYTPLHIA 360
G TPLH A
Sbjct: 688 KDGDTPLHEA 697
Score = 98.7 bits (235), Expect = 7e-20
Identities = 94/294 (31%), Positives = 135/294 (45%), Gaps = 16/294 (5%)
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
EAE G R A+ A + + ++ L + D + + +T LH++ G + VK L
Sbjct: 482 EAEDKDGDR-AVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTL 540
Query: 137 LDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLS 195
LD G HP+ DS +T PLH A S K + VL+ GADV ++ + LH+A L
Sbjct: 541 LDFGCHPSLQDSEGDT---PLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALR 597
Query: 196 DAPEVVKELLEAGACP---DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
P ++ LL P D + T LH+AA +LL++ G +
Sbjct: 598 GNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQ 657
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
TALHLA E H + RLL+ GA +D + G TPLH A +L + L D DV
Sbjct: 658 QTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQLRQLQD-MQDVG 716
Query: 313 AKDA----DGRTPLHGAIVRGAR---ACDIARLLLSAGADPNAADNFGYTPLHI 359
DA T + G +GA A IA L + GAD + + G +PL +
Sbjct: 717 KVDAAWEPSKNTLIMGLGTQGAEKKSAASIACFLAANGADLSIRNKKGQSPLDL 770
Score = 83.0 bits (196), Expect = 3e-15
Identities = 73/267 (27%), Positives = 122/267 (45%), Gaps = 9/267 (3%)
Query: 160 AASAKSLACVKVLIAH-GADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA+ +A V+ L+ DVN + + + A + +++K LL+ +
Sbjct: 429 AAANGDVAKVEDLLKRPDVDVNGQCAGHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDG 488
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
+ +H AA + ++L AD+ A + T LH+A GH + + LLD G H
Sbjct: 489 DRAVHHAAFGDEGAVIEVLHRGSADLNAR-NKRRQTPLHIAVNKGHLQVVKTLLDFGCHP 547
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ G TPLH A + +++ +L++ ADV + +G LH A +RG + R+
Sbjct: 548 SLQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAALRGNPSA--MRV 605
Query: 339 LLSAGADPNAAD---NFGYTPLHIAALNEFSACVLLLLDYG-GDVTLRTNGGVSALSFIV 394
LLS P D + GYT LH+AALN LL+ G ++ ++ +AL V
Sbjct: 606 LLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAV 665
Query: 395 RRVPDVIPRYLCKFDDAVHVSEHELGD 421
R I R L + + + + + GD
Sbjct: 666 ERQHTQIVRLLVRAGAKLDIQDKD-GD 691
>AL158217-11|CAI22163.1| 854|Homo sapiens espin protein.
Length = 854
Score = 102 bits (244), Expect = 5e-21
Identities = 87/275 (31%), Positives = 125/275 (45%), Gaps = 12/275 (4%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD-- 178
+H + G C++ L++ A P + ATP H A++ LAC++ L++ G
Sbjct: 40 VHHAARAGKLHCLRFLVEEAALPAA--ARARNGATPAHDASATGHLACLQWLLSQGGCRV 97
Query: 179 VNAGLSDRSPLHYAVLSDAPEVVKELLE-AGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ S + LH A PEVV LL G P P+H AA+ G +LL
Sbjct: 98 QDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLL 157
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQ 296
+ + A AT L+LA ++GH E + L+ GA G TPLH A
Sbjct: 158 VEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMG 217
Query: 297 SLEVVEMLVDRCADVRA--KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGY 354
V+ LV C DV +D DG T +H A RG ++ LLL G +AD +G
Sbjct: 218 HSPVIVWLVS-CTDVSLSEQDKDGATAMHFAASRGHTKV-LSWLLLHGGEI--SADLWGG 273
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
TPLH AA N C +L+ G ++ +R G +A
Sbjct: 274 TPLHDAAENGELECCQILVVNGAELDVRDRDGYTA 308
Score = 96.3 bits (229), Expect = 4e-19
Identities = 74/225 (32%), Positives = 108/225 (48%), Gaps = 6/225 (2%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
L + L + G + D++G T LHL+ G E V LL HG T ++T+ A P+H
Sbjct: 86 LQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPT--AATDMGALPIH 143
Query: 159 CAASAKSLACVKVLIAHGAD-VNAGLSD-RSPLHYAVLSDAPEVVKELL-EAGACPDTPQ 215
AA+ +++L+ H + VNA + +PL+ A EV + L+ E GA P
Sbjct: 144 YAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARA 203
Query: 216 VFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
TPLH AA +G + L++ + ATA+H AA GH + LL HG
Sbjct: 204 HDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHG 263
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
I + G TPLH A LE ++LV A++ +D DG T
Sbjct: 264 GEIS-ADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYT 307
Score = 88.6 bits (210), Expect = 7e-17
Identities = 77/239 (32%), Positives = 108/239 (45%), Gaps = 8/239 (3%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACP 211
A P+H AA A L C++ L+ A A + +P H A + ++ LL G C
Sbjct: 37 ALPVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCR 96
Query: 212 DTPQVFT-ETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + T LH+AA G LL+ G D AA G A +H AA G R
Sbjct: 97 VQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMG-ALPIHYAAAKGDFPSLR 155
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIV 327
LL++H ++ G TPL+LA LEV + LV C AD A+ DG TPLH A
Sbjct: 156 LLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQ 215
Query: 328 RGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
G + I L+ + D G T +H AA + + LL +GG+++ GG
Sbjct: 216 MG-HSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISADLWGG 273
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/189 (30%), Positives = 88/189 (46%), Gaps = 7/189 (3%)
Query: 107 GVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSL 166
G DP D G +H + G ++LL++H +P ++ T+ ATPL+ A L
Sbjct: 128 GGDPTAATDMGALPIHYAAAKGDFPSLRLLVEH--YPEGVNAQTKNGATPLYLACQEGHL 185
Query: 167 ACVKVLIAH-GADVNAGLSD-RSPLHYAV-LSDAPEVVKELLEAGACPDTPQVFTETPLH 223
+ L+ GAD +A D +PLH A + +P +V + T +H
Sbjct: 186 EVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMH 245
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
AAS G LL G ++ A + G T LH AAE+G EC ++L+ +GA +D +
Sbjct: 246 FAASRGHTKVLSWLLLHGGEISADLWGG--TPLHDAAENGELECCQILVVNGAELDVRDR 303
Query: 284 RGQTPLHLA 292
G T L+
Sbjct: 304 DGYTAADLS 312
Score = 70.9 bits (166), Expect = 2e-11
Identities = 74/263 (28%), Positives = 108/263 (41%), Gaps = 15/263 (5%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G T H + G C++ LL G + AT LH AA V L+ HG
Sbjct: 70 GATPAHDASATGHLACLQWLLSQGGC--RVQDKDNSGATVLHLAARFGHPEVVNWLLHHG 127
Query: 177 ADVNAGLSDRS--PLHYAVLSDAPEVVKELLEAGACPDTPQVFTE---TPLHVAASLGSA 231
+D P+HYA ++ L+E P+ T+ TPL++A G
Sbjct: 128 GGDPTAATDMGALPIHYAAAKGDFPSLRLLVEH--YPEGVNAQTKNGATPLYLACQEGHL 185
Query: 232 SCTKLLLN-AGADVRAAMGPGKATALHLAAEDGHAECARLLLD-HGAHIDWPNFRGQTPL 289
T+ L+ GAD A G T LH AA+ GH+ L+ + + G T +
Sbjct: 186 EVTQYLVQECGADPHARAHDGM-TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAM 244
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
H A +V+ L+ ++ A D G TPLH A G C ++L+ GA+ +
Sbjct: 245 HFAASRGHTKVLSWLLLHGGEISA-DLWGGTPLHDAAENGELEC--CQILVVNGAELDVR 301
Query: 350 DNFGYTPLHIAALNEFSACVLLL 372
D GYT ++ N S C L
Sbjct: 302 DRDGYTAADLSDFNGHSHCTRYL 324
>AL031848-3|CAI19773.1| 854|Homo sapiens espin protein.
Length = 854
Score = 102 bits (244), Expect = 5e-21
Identities = 87/275 (31%), Positives = 125/275 (45%), Gaps = 12/275 (4%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD-- 178
+H + G C++ L++ A P + ATP H A++ LAC++ L++ G
Sbjct: 40 VHHAARAGKLHCLRFLVEEAALPAA--ARARNGATPAHDASATGHLACLQWLLSQGGCRV 97
Query: 179 VNAGLSDRSPLHYAVLSDAPEVVKELLE-AGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ S + LH A PEVV LL G P P+H AA+ G +LL
Sbjct: 98 QDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYAAAKGDFPSLRLL 157
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH-GAHIDWPNFRGQTPLHLATLAQ 296
+ + A AT L+LA ++GH E + L+ GA G TPLH A
Sbjct: 158 VEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMG 217
Query: 297 SLEVVEMLVDRCADVRA--KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGY 354
V+ LV C DV +D DG T +H A RG ++ LLL G +AD +G
Sbjct: 218 HSPVIVWLVS-CTDVSLSEQDKDGATAMHFAASRGHTKV-LSWLLLHGGEI--SADLWGG 273
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
TPLH AA N C +L+ G ++ +R G +A
Sbjct: 274 TPLHDAAENGELECCQILVVNGAELDVRDRDGYTA 308
Score = 96.3 bits (229), Expect = 4e-19
Identities = 74/225 (32%), Positives = 108/225 (48%), Gaps = 6/225 (2%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
L + L + G + D++G T LHL+ G E V LL HG T ++T+ A P+H
Sbjct: 86 LQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPT--AATDMGALPIH 143
Query: 159 CAASAKSLACVKVLIAHGAD-VNAGLSD-RSPLHYAVLSDAPEVVKELL-EAGACPDTPQ 215
AA+ +++L+ H + VNA + +PL+ A EV + L+ E GA P
Sbjct: 144 YAAAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARA 203
Query: 216 VFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
TPLH AA +G + L++ + ATA+H AA GH + LL HG
Sbjct: 204 HDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHG 263
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
I + G TPLH A LE ++LV A++ +D DG T
Sbjct: 264 GEIS-ADLWGGTPLHDAAENGELECCQILVVNGAELDVRDRDGYT 307
Score = 88.6 bits (210), Expect = 7e-17
Identities = 77/239 (32%), Positives = 108/239 (45%), Gaps = 8/239 (3%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADVNAGLSDR--SPLHYAVLSDAPEVVKELLEAGACP 211
A P+H AA A L C++ L+ A A + +P H A + ++ LL G C
Sbjct: 37 ALPVHHAARAGKLHCLRFLVEEAALPAAARARNGATPAHDASATGHLACLQWLLSQGGCR 96
Query: 212 DTPQVFT-ETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + T LH+AA G LL+ G D AA G A +H AA G R
Sbjct: 97 VQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMG-ALPIHYAAAKGDFPSLR 155
Query: 270 LLLDHGAH-IDWPNFRGQTPLHLATLAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIV 327
LL++H ++ G TPL+LA LEV + LV C AD A+ DG TPLH A
Sbjct: 156 LLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQ 215
Query: 328 RGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGG 386
G + I L+ + D G T +H AA + + LL +GG+++ GG
Sbjct: 216 MG-HSPVIVWLVSCTDVSLSEQDKDGATAMHFAASRGHTKVLSWLLLHGGEISADLWGG 273
Score = 73.7 bits (173), Expect = 2e-12
Identities = 57/189 (30%), Positives = 88/189 (46%), Gaps = 7/189 (3%)
Query: 107 GVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSL 166
G DP D G +H + G ++LL++H +P ++ T+ ATPL+ A L
Sbjct: 128 GGDPTAATDMGALPIHYAAAKGDFPSLRLLVEH--YPEGVNAQTKNGATPLYLACQEGHL 185
Query: 167 ACVKVLIAH-GADVNAGLSD-RSPLHYAV-LSDAPEVVKELLEAGACPDTPQVFTETPLH 223
+ L+ GAD +A D +PLH A + +P +V + T +H
Sbjct: 186 EVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAMH 245
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
AAS G LL G ++ A + G T LH AAE+G EC ++L+ +GA +D +
Sbjct: 246 FAASRGHTKVLSWLLLHGGEISADLWGG--TPLHDAAENGELECCQILVVNGAELDVRDR 303
Query: 284 RGQTPLHLA 292
G T L+
Sbjct: 304 DGYTAADLS 312
Score = 70.9 bits (166), Expect = 2e-11
Identities = 74/263 (28%), Positives = 108/263 (41%), Gaps = 15/263 (5%)
Query: 117 GRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG 176
G T H + G C++ LL G + AT LH AA V L+ HG
Sbjct: 70 GATPAHDASATGHLACLQWLLSQGGC--RVQDKDNSGATVLHLAARFGHPEVVNWLLHHG 127
Query: 177 ADVNAGLSDRS--PLHYAVLSDAPEVVKELLEAGACPDTPQVFTE---TPLHVAASLGSA 231
+D P+HYA ++ L+E P+ T+ TPL++A G
Sbjct: 128 GGDPTAATDMGALPIHYAAAKGDFPSLRLLVEH--YPEGVNAQTKNGATPLYLACQEGHL 185
Query: 232 SCTKLLLN-AGADVRAAMGPGKATALHLAAEDGHAECARLLLD-HGAHIDWPNFRGQTPL 289
T+ L+ GAD A G T LH AA+ GH+ L+ + + G T +
Sbjct: 186 EVTQYLVQECGADPHARAHDGM-TPLHAAAQMGHSPVIVWLVSCTDVSLSEQDKDGATAM 244
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAA 349
H A +V+ L+ ++ A D G TPLH A G C ++L+ GA+ +
Sbjct: 245 HFAASRGHTKVLSWLLLHGGEISA-DLWGGTPLHDAAENGELEC--CQILVVNGAELDVR 301
Query: 350 DNFGYTPLHIAALNEFSACVLLL 372
D GYT ++ N S C L
Sbjct: 302 DRDGYTAADLSDFNGHSHCTRYL 324
>BX005460-4|CAM26150.1| 297|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 297
Score = 101 bits (242), Expect = 9e-21
Identities = 84/240 (35%), Positives = 119/240 (49%), Gaps = 25/240 (10%)
Query: 152 TKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGAC 210
+K TPLH AA S+ VL+ GA++NA R+PL AV+++ EV + +++ G C
Sbjct: 1 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 60
Query: 211 PDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + T LH AA +G+ LLL+ G DV A G+ L + H +
Sbjct: 61 VYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQ---GQLPPPSLPS---HPQ--- 111
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
D G G TP+ A + +EV+ ML+ R ADV D + LH A G
Sbjct: 112 ---DSG---------GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTG 159
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ A IA +LL+A D +A + G TPLHIAA + CVLL L G + LR G +A
Sbjct: 160 SAA--IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTA 217
Score = 60.1 bits (139), Expect = 3e-08
Identities = 63/218 (28%), Positives = 92/218 (42%), Gaps = 19/218 (8%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
RT LH + GS E +LL GA+ N D + + TPL A L + ++ G
Sbjct: 3 RTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEAVVNNHLEVARYMVQRGG 59
Query: 178 DVNAGLSDRSP-LHYAVLSDAPEVVKELLEAG-------------ACPDTPQVFTE-TPL 222
V + D S LH+A E+V LL G + P PQ TP+
Sbjct: 60 CVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPI 119
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA ++LL GADV + LH A+ G A A +LL+ + N
Sbjct: 120 IWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDLHAVN 178
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 179 YHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 216
Score = 54.8 bits (126), Expect = 1e-06
Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 12/142 (8%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHG---------AHPNTWDSSTETKA--TPLHCAAS 162
++ G TCLH + +G+ E V LLL G P + S + TP+ AA
Sbjct: 65 EEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPIIWAAE 124
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + +++L+ GADV ++ + LH+A + + + + LL A +TP
Sbjct: 125 HKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTP 184
Query: 222 LHVAASLGSASCTKLLLNAGAD 243
LH+AA C L L+ GA+
Sbjct: 185 LHIAARESYHDCVLLFLSRGAN 206
Score = 41.9 bits (94), Expect = 0.008
Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
RTPLH A +G+ +I +LL AGA+ NA D TPL A +N ++ GG
Sbjct: 3 RTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 60
Query: 379 VTLRTNGGVSAL 390
V + G + L
Sbjct: 61 VYSKEEDGSTCL 72
Score = 37.1 bits (82), Expect = 0.23
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T I+WA ++ LL G D D+ CLH + GS ++LL+ +
Sbjct: 117 TPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHA 176
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ + TPLH AA CV + ++ GA+
Sbjct: 177 VNYHGD---TPLHIAARESYHDCVLLFLSRGAN 206
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 154 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 213
Query: 150 TET 152
+T
Sbjct: 214 GDT 216
>BT006845-1|AAP35491.1| 528|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16A protein.
Length = 528
Score = 101 bits (242), Expect = 9e-21
Identities = 77/221 (34%), Positives = 108/221 (48%), Gaps = 7/221 (3%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+ L GV PD ++ G T LH C+ E V+ LL+ GA+ N DS T PLH AA
Sbjct: 89 QFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWT---PLHAAA 145
Query: 162 SAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ L V++LIA GA++ A +D + + Y + D E + LE +
Sbjct: 146 TCGHLHLVELLIASGANLLAVNTDGN-MPYDLCDD--EQTLDCLETAMADRGITQDSIEA 202
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L + L AGAD+ A + G AT LH+AA +G +E A LLL+H A +
Sbjct: 203 ARAVPELRMLDDIRSRLQAGADLHAPLDHG-ATLLHVAAANGFSEAAALLLEHRASLSAK 261
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ G PLH A + +VE+LV AD+ AK TPL
Sbjct: 262 DQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDETPL 302
Score = 68.5 bits (160), Expect = 8e-11
Identities = 59/189 (31%), Positives = 82/189 (43%), Gaps = 9/189 (4%)
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
E V++ L +G PD T LH + LL AGA++ A T LH
Sbjct: 85 EEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECW-TPLHA 143
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM-LVDRCADVRAKDAD 317
AA GH LL+ GA++ N G P L Q+L+ +E + DR + +A
Sbjct: 144 AATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMADRGITQDSIEAA 203
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
P R D R L AGAD +A + G T LH+AA N FS LLL++
Sbjct: 204 RAVP-------ELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRA 256
Query: 378 DVTLRTNGG 386
++ + G
Sbjct: 257 SLSAKDQDG 265
Score = 64.9 bits (151), Expect = 1e-09
Identities = 64/226 (28%), Positives = 97/226 (42%), Gaps = 10/226 (4%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA+ L V+ + G + D + LH + D E+V++LLEAGA +
Sbjct: 78 AAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSEC 137
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL-DHGAH 277
TPLH AA+ G +LL+ +GA++ A G L ++ +C + D G
Sbjct: 138 WTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMP-YDLCDDEQTLDCLETAMADRGIT 196
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIAR 337
D P + L+ + + AD+ A G T LH A G + A
Sbjct: 197 QDSIEAARAVPE-----LRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFS--EAAA 249
Query: 338 LLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
LLL A +A D G+ PLH AA V LL+ +G D+ ++
Sbjct: 250 LLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKS 295
Score = 63.3 bits (147), Expect = 3e-09
Identities = 74/253 (29%), Positives = 101/253 (39%), Gaps = 12/253 (4%)
Query: 131 ECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPL 189
E V+ L G P D + E T LH V+ L+ GA++NA S+ +PL
Sbjct: 85 EEVRQFLGSGVSP---DLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPL 141
Query: 190 HYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
H A +V+ L+ +GA P + + C L A AD +
Sbjct: 142 HAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDC---LETAMAD--RGIT 196
Query: 250 PGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA 309
A E + R L GA + P G T LH+A E +L++ A
Sbjct: 197 QDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRA 256
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
+ AKD DG PLH A G + LL++ GAD NA TPL + E A
Sbjct: 257 SLSAKDQDGWEPLHAAAYWG--QVPLVELLVAHGADLNAKSLMDETPLDVCGDEEVRA-K 313
Query: 370 LLLLDYGGDVTLR 382
LL L + D LR
Sbjct: 314 LLELKHKHDALLR 326
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
++ + P L AA + E R L G D N G T LH + E+V+
Sbjct: 64 LKQVLFPPSVVLLEAAARNDLEE-VRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQ 122
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
L++ A++ A D++ TPLH A G + LL+++GA+ A + G P
Sbjct: 123 LLEAGANINACDSECWTPLHAAATCG--HLHLVELLIASGANLLAVNTDGNMP 173
>BC053506-1|AAH53506.1| 528|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16A protein.
Length = 528
Score = 101 bits (242), Expect = 9e-21
Identities = 77/221 (34%), Positives = 108/221 (48%), Gaps = 7/221 (3%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+ L GV PD ++ G T LH C+ E V+ LL+ GA+ N DS T PLH AA
Sbjct: 89 QFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWT---PLHAAA 145
Query: 162 SAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ L V++LIA GA++ A +D + + Y + D E + LE +
Sbjct: 146 TCGHLHLVELLIASGANLLAVNTDGN-MPYDLCDD--EQTLDCLETAMADRGITQDSIEA 202
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L + L AGAD+ A + G AT LH+AA +G +E A LLL+H A +
Sbjct: 203 ARAVPELRMLDDIRSRLQAGADLHAPLDHG-ATLLHVAAANGFSEAAALLLEHRASLSAK 261
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ G PLH A + +VE+LV AD+ AK TPL
Sbjct: 262 DQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDETPL 302
Score = 68.5 bits (160), Expect = 8e-11
Identities = 59/189 (31%), Positives = 82/189 (43%), Gaps = 9/189 (4%)
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
E V++ L +G PD T LH + LL AGA++ A T LH
Sbjct: 85 EEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECW-TPLHA 143
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM-LVDRCADVRAKDAD 317
AA GH LL+ GA++ N G P L Q+L+ +E + DR + +A
Sbjct: 144 AATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMADRGITQDSIEAA 203
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
P R D R L AGAD +A + G T LH+AA N FS LLL++
Sbjct: 204 RAVP-------ELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRA 256
Query: 378 DVTLRTNGG 386
++ + G
Sbjct: 257 SLSAKDQDG 265
Score = 64.9 bits (151), Expect = 1e-09
Identities = 64/226 (28%), Positives = 97/226 (42%), Gaps = 10/226 (4%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA+ L V+ + G + D + LH + D E+V++LLEAGA +
Sbjct: 78 AAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSEC 137
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL-DHGAH 277
TPLH AA+ G +LL+ +GA++ A G L ++ +C + D G
Sbjct: 138 WTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMP-YDLCDDEQTLDCLETAMADRGIT 196
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIAR 337
D P + L+ + + AD+ A G T LH A G + A
Sbjct: 197 QDSIEAARAVPE-----LRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFS--EAAA 249
Query: 338 LLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
LLL A +A D G+ PLH AA V LL+ +G D+ ++
Sbjct: 250 LLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKS 295
Score = 63.3 bits (147), Expect = 3e-09
Identities = 74/253 (29%), Positives = 101/253 (39%), Gaps = 12/253 (4%)
Query: 131 ECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPL 189
E V+ L G P D + E T LH V+ L+ GA++NA S+ +PL
Sbjct: 85 EEVRQFLGSGVSP---DLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPL 141
Query: 190 HYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
H A +V+ L+ +GA P + + C L A AD +
Sbjct: 142 HAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDC---LETAMAD--RGIT 196
Query: 250 PGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA 309
A E + R L GA + P G T LH+A E +L++ A
Sbjct: 197 QDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRA 256
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
+ AKD DG PLH A G + LL++ GAD NA TPL + E A
Sbjct: 257 SLSAKDQDGWEPLHAAAYWG--QVPLVELLVAHGADLNAKSLMDETPLDVCGDEEVRA-K 313
Query: 370 LLLLDYGGDVTLR 382
LL L + D LR
Sbjct: 314 LLELKHKHDALLR 326
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
++ + P L AA + E R L G D N G T LH + E+V+
Sbjct: 64 LKQVLFPPSVVLLEAAARNDLEE-VRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQ 122
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
L++ A++ A D++ TPLH A G + LL+++GA+ A + G P
Sbjct: 123 LLEAGANINACDSECWTPLHAAATCG--HLHLVELLIASGANLLAVNTDGNMP 173
>BC049841-1|AAH49841.1| 528|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16A protein.
Length = 528
Score = 101 bits (242), Expect = 9e-21
Identities = 77/221 (34%), Positives = 108/221 (48%), Gaps = 7/221 (3%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+ L GV PD ++ G T LH C+ E V+ LL+ GA+ N DS T PLH AA
Sbjct: 89 QFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWT---PLHAAA 145
Query: 162 SAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ L V++LIA GA++ A +D + + Y + D E + LE +
Sbjct: 146 TCGHLHLVELLIASGANLLAVNTDGN-MPYDLCDD--EQTLDCLETAMADRGITQDSIEA 202
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L + L AGAD+ A + G AT LH+AA +G +E A LLL+H A +
Sbjct: 203 ARAVPELRMLDDIRSRLQAGADLHAPLDHG-ATLLHVAAANGFSEAAALLLEHRASLSAK 261
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ G PLH A + +VE+LV AD+ AK TPL
Sbjct: 262 DQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDETPL 302
Score = 68.5 bits (160), Expect = 8e-11
Identities = 59/189 (31%), Positives = 82/189 (43%), Gaps = 9/189 (4%)
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
E V++ L +G PD T LH + LL AGA++ A T LH
Sbjct: 85 EEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECW-TPLHA 143
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM-LVDRCADVRAKDAD 317
AA GH LL+ GA++ N G P L Q+L+ +E + DR + +A
Sbjct: 144 AATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMADRGITQDSIEAA 203
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
P R D R L AGAD +A + G T LH+AA N FS LLL++
Sbjct: 204 RAVP-------ELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRA 256
Query: 378 DVTLRTNGG 386
++ + G
Sbjct: 257 SLSAKDQDG 265
Score = 64.9 bits (151), Expect = 1e-09
Identities = 64/226 (28%), Positives = 97/226 (42%), Gaps = 10/226 (4%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA+ L V+ + G + D + LH + D E+V++LLEAGA +
Sbjct: 78 AAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSEC 137
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL-DHGAH 277
TPLH AA+ G +LL+ +GA++ A G L ++ +C + D G
Sbjct: 138 WTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMP-YDLCDDEQTLDCLETAMADRGIT 196
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIAR 337
D P + L+ + + AD+ A G T LH A G + A
Sbjct: 197 QDSIEAARAVPE-----LRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFS--EAAA 249
Query: 338 LLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
LLL A +A D G+ PLH AA V LL+ +G D+ ++
Sbjct: 250 LLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKS 295
Score = 63.3 bits (147), Expect = 3e-09
Identities = 74/253 (29%), Positives = 101/253 (39%), Gaps = 12/253 (4%)
Query: 131 ECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPL 189
E V+ L G P D + E T LH V+ L+ GA++NA S+ +PL
Sbjct: 85 EEVRQFLGSGVSP---DLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPL 141
Query: 190 HYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
H A +V+ L+ +GA P + + C L A AD +
Sbjct: 142 HAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDC---LETAMAD--RGIT 196
Query: 250 PGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA 309
A E + R L GA + P G T LH+A E +L++ A
Sbjct: 197 QDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRA 256
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
+ AKD DG PLH A G + LL++ GAD NA TPL + E A
Sbjct: 257 SLSAKDQDGWEPLHAAAYWG--QVPLVELLVAHGADLNAKSLMDETPLDVCGDEEVRA-K 313
Query: 370 LLLLDYGGDVTLR 382
LL L + D LR
Sbjct: 314 LLELKHKHDALLR 326
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
++ + P L AA + E R L G D N G T LH + E+V+
Sbjct: 64 LKQVLFPPSVVLLEAAARNDLEE-VRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQ 122
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
L++ A++ A D++ TPLH A G + LL+++GA+ A + G P
Sbjct: 123 LLEAGANINACDSECWTPLHAAATCG--HLHLVELLIASGANLLAVNTDGNMP 173
>BC007854-1|AAH07854.1| 528|Homo sapiens protein phosphatase 1,
regulatory (inhibitor) subunit 16A protein.
Length = 528
Score = 101 bits (242), Expect = 9e-21
Identities = 77/221 (34%), Positives = 108/221 (48%), Gaps = 7/221 (3%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
+ L GV PD ++ G T LH C+ E V+ LL+ GA+ N DS T PLH AA
Sbjct: 89 QFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWT---PLHAAA 145
Query: 162 SAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ L V++LIA GA++ A +D + + Y + D E + LE +
Sbjct: 146 TCGHLHLVELLIASGANLLAVNTDGN-MPYDLCDD--EQTLDCLETAMADRGITQDSIEA 202
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L + L AGAD+ A + G AT LH+AA +G +E A LLL+H A +
Sbjct: 203 ARAVPELRMLDDIRSRLQAGADLHAPLDHG-ATLLHVAAANGFSEAAALLLEHRASLSAK 261
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ G PLH A + +VE+LV AD+ AK TPL
Sbjct: 262 DQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDETPL 302
Score = 68.5 bits (160), Expect = 8e-11
Identities = 59/189 (31%), Positives = 82/189 (43%), Gaps = 9/189 (4%)
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
E V++ L +G PD T LH + LL AGA++ A T LH
Sbjct: 85 EEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECW-TPLHA 143
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM-LVDRCADVRAKDAD 317
AA GH LL+ GA++ N G P L Q+L+ +E + DR + +A
Sbjct: 144 AATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMADRGITQDSIEAA 203
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
P R D R L AGAD +A + G T LH+AA N FS LLL++
Sbjct: 204 RAVP-------ELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRA 256
Query: 378 DVTLRTNGG 386
++ + G
Sbjct: 257 SLSAKDQDG 265
Score = 64.9 bits (151), Expect = 1e-09
Identities = 64/226 (28%), Positives = 97/226 (42%), Gaps = 10/226 (4%)
Query: 160 AASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
AA+ L V+ + G + D + LH + D E+V++LLEAGA +
Sbjct: 78 AAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSEC 137
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL-DHGAH 277
TPLH AA+ G +LL+ +GA++ A G L ++ +C + D G
Sbjct: 138 WTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMP-YDLCDDEQTLDCLETAMADRGIT 196
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIAR 337
D P + L+ + + AD+ A G T LH A G + A
Sbjct: 197 QDSIEAARAVPE-----LRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFS--EAAA 249
Query: 338 LLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRT 383
LLL A +A D G+ PLH AA V LL+ +G D+ ++
Sbjct: 250 LLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKS 295
Score = 63.3 bits (147), Expect = 3e-09
Identities = 74/253 (29%), Positives = 101/253 (39%), Gaps = 12/253 (4%)
Query: 131 ECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPL 189
E V+ L G P D + E T LH V+ L+ GA++NA S+ +PL
Sbjct: 85 EEVRQFLGSGVSP---DLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPL 141
Query: 190 HYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG 249
H A +V+ L+ +GA P + + C L A AD +
Sbjct: 142 HAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDC---LETAMAD--RGIT 196
Query: 250 PGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA 309
A E + R L GA + P G T LH+A E +L++ A
Sbjct: 197 QDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRA 256
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
+ AKD DG PLH A G + LL++ GAD NA TPL + E A
Sbjct: 257 SLSAKDQDGWEPLHAAAYWG--QVPLVELLVAHGADLNAKSLMDETPLDVCGDEEVRA-K 313
Query: 370 LLLLDYGGDVTLR 382
LL L + D LR
Sbjct: 314 LLELKHKHDALLR 326
Score = 44.8 bits (101), Expect = 0.001
Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
++ + P L AA + E R L G D N G T LH + E+V+
Sbjct: 64 LKQVLFPPSVVLLEAAARNDLEE-VRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQ 122
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTP 356
L++ A++ A D++ TPLH A G + LL+++GA+ A + G P
Sbjct: 123 LLEAGANINACDSECWTPLHAAATCG--HLHLVELLIASGANLLAVNTDGNMP 173
>AL671762-12|CAI18225.2| 297|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 297
Score = 101 bits (242), Expect = 9e-21
Identities = 84/240 (35%), Positives = 119/240 (49%), Gaps = 25/240 (10%)
Query: 152 TKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGAC 210
+K TPLH AA S+ VL+ GA++NA R+PL AV+++ EV + +++ G C
Sbjct: 1 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 60
Query: 211 PDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + T LH AA +G+ LLL+ G DV A G+ L + H +
Sbjct: 61 VYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQ---GQLPPPSLPS---HPQ--- 111
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
D G G TP+ A + +EV+ ML+ R ADV D + LH A G
Sbjct: 112 ---DSG---------GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTG 159
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ A IA +LL+A D +A + G TPLHIAA + CVLL L G + LR G +A
Sbjct: 160 SAA--IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTA 217
Score = 60.1 bits (139), Expect = 3e-08
Identities = 63/218 (28%), Positives = 92/218 (42%), Gaps = 19/218 (8%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
RT LH + GS E +LL GA+ N D + + TPL A L + ++ G
Sbjct: 3 RTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEAVVNNHLEVARYMVQRGG 59
Query: 178 DVNAGLSDRSP-LHYAVLSDAPEVVKELLEAG-------------ACPDTPQVFTE-TPL 222
V + D S LH+A E+V LL G + P PQ TP+
Sbjct: 60 CVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPI 119
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA ++LL GADV + LH A+ G A A +LL+ + N
Sbjct: 120 IWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDLHAVN 178
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 179 YHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 216
Score = 54.8 bits (126), Expect = 1e-06
Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 12/142 (8%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHG---------AHPNTWDSSTETKA--TPLHCAAS 162
++ G TCLH + +G+ E V LLL G P + S + TP+ AA
Sbjct: 65 EEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPIIWAAE 124
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + +++L+ GADV ++ + LH+A + + + + LL A +TP
Sbjct: 125 HKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTP 184
Query: 222 LHVAASLGSASCTKLLLNAGAD 243
LH+AA C L L+ GA+
Sbjct: 185 LHIAARESYHDCVLLFLSRGAN 206
Score = 41.9 bits (94), Expect = 0.008
Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
RTPLH A +G+ +I +LL AGA+ NA D TPL A +N ++ GG
Sbjct: 3 RTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 60
Query: 379 VTLRTNGGVSAL 390
V + G + L
Sbjct: 61 VYSKEEDGSTCL 72
Score = 37.1 bits (82), Expect = 0.23
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T I+WA ++ LL G D D+ CLH + GS ++LL+ +
Sbjct: 117 TPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHA 176
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ + TPLH AA CV + ++ GA+
Sbjct: 177 VNYHGD---TPLHIAARESYHDCVLLFLSRGAN 206
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 154 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 213
Query: 150 TET 152
+T
Sbjct: 214 GDT 216
>AL662834-23|CAM24991.1| 297|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 297
Score = 101 bits (242), Expect = 9e-21
Identities = 84/240 (35%), Positives = 119/240 (49%), Gaps = 25/240 (10%)
Query: 152 TKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGAC 210
+K TPLH AA S+ VL+ GA++NA R+PL AV+++ EV + +++ G C
Sbjct: 1 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 60
Query: 211 PDTPQVFTETPLHVAASLGSASCTKLLLNAG-ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + T LH AA +G+ LLL+ G DV A G+ L + H +
Sbjct: 61 VYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQ---GQLPPPSLPS---HPQ--- 111
Query: 270 LLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRG 329
D G G TP+ A + +EV+ ML+ R ADV D + LH A G
Sbjct: 112 ---DSG---------GWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTG 159
Query: 330 ARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ A IA +LL+A D +A + G TPLHIAA + CVLL L G + LR G +A
Sbjct: 160 SAA--IAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTA 217
Score = 60.1 bits (139), Expect = 3e-08
Identities = 63/218 (28%), Positives = 92/218 (42%), Gaps = 19/218 (8%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
RT LH + GS E +LL GA+ N D + + TPL A L + ++ G
Sbjct: 3 RTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEAVVNNHLEVARYMVQRGG 59
Query: 178 DVNAGLSDRSP-LHYAVLSDAPEVVKELLEAG-------------ACPDTPQVFTE-TPL 222
V + D S LH+A E+V LL G + P PQ TP+
Sbjct: 60 CVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPI 119
Query: 223 HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPN 282
AA ++LL GADV + LH A+ G A A +LL+ + N
Sbjct: 120 IWAAEHKHIEVIRMLLTRGADVTLTDNE-ENICLHWASFTGSAAIAEVLLNARCDLHAVN 178
Query: 283 FRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 179 YHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 216
Score = 54.8 bits (126), Expect = 1e-06
Identities = 41/142 (28%), Positives = 66/142 (46%), Gaps = 12/142 (8%)
Query: 114 DDAGRTCLHLSCLVGSEECVKLLLDHG---------AHPNTWDSSTETKA--TPLHCAAS 162
++ G TCLH + +G+ E V LLL G P + S + TP+ AA
Sbjct: 65 EEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQGQLPPPSLPSHPQDSGGWTPIIWAAE 124
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
K + +++L+ GADV ++ + LH+A + + + + LL A +TP
Sbjct: 125 HKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTP 184
Query: 222 LHVAASLGSASCTKLLLNAGAD 243
LH+AA C L L+ GA+
Sbjct: 185 LHIAARESYHDCVLLFLSRGAN 206
Score = 41.9 bits (94), Expect = 0.008
Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
RTPLH A +G+ +I +LL AGA+ NA D TPL A +N ++ GG
Sbjct: 3 RTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 60
Query: 379 VTLRTNGGVSAL 390
V + G + L
Sbjct: 61 VYSKEEDGSTCL 72
Score = 37.1 bits (82), Expect = 0.23
Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T I+WA ++ LL G D D+ CLH + GS ++LL+ +
Sbjct: 117 TPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVLLNARCDLHA 176
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
+ + TPLH AA CV + ++ GA+
Sbjct: 177 VNYHGD---TPLHIAARESYHDCVLLFLSRGAN 206
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 154 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 213
Query: 150 TET 152
+T
Sbjct: 214 GDT 216
>AF403034-1|AAL57353.1| 253|Homo sapiens ankyrin repeat
domain-containing SOCS box protein Asb-16 protein.
Length = 253
Score = 101 bits (242), Expect = 9e-21
Identities = 74/224 (33%), Positives = 103/224 (45%), Gaps = 11/224 (4%)
Query: 146 WDSSTETKAT-PLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKEL 204
W + +TK T PL A + C + LI GA+++A + R+ LH A + V+ L
Sbjct: 2 WVLTPKTKQTAPLAIATARGYTDCARHLIRQGAELDARVGGRAALHEACARAQFDCVRLL 61
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
L GA + TPLH+ S C KLLL AGA V A G + T LH+AA G
Sbjct: 62 LTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGL 121
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLA--------TLAQSLEVVEMLVDRCADVRAKDA 316
+ L L+HGA + +G+T L+ A + + L++ AD RA
Sbjct: 122 EQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGR 181
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
TPLH A G +A LLL GA + G+TP+ A
Sbjct: 182 KRHTPLHNACASGCGG--LAELLLRYGARAEVPNGAGHTPMDCA 223
Score = 85.4 bits (202), Expect = 7e-16
Identities = 68/220 (30%), Positives = 96/220 (43%), Gaps = 9/220 (4%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+PL A + + L+ GA D +V LH A + C +LLL GA
Sbjct: 12 APLAIATARGYTDCARHLIRQGAELDA-RVGGRAALHEACARAQFDCVRLLLTFGAKANV 70
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSLEVVEMLV 305
G T LHL +CA+LLL+ GA ++ Q TPLH+A + V + +
Sbjct: 71 LTEEG-TTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYL 129
Query: 306 DRCADVRAKDADGRTPLHGAIV--RGARACD----IARLLLSAGADPNAADNFGYTPLHI 359
+ ADV + + G T L+ A G +C AR LL AGAD AA +TPLH
Sbjct: 130 EHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHN 189
Query: 360 AALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
A + LLL YG + G + + ++ V D
Sbjct: 190 ACASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQAVQD 229
Score = 71.3 bits (167), Expect = 1e-11
Identities = 60/189 (31%), Positives = 82/189 (43%), Gaps = 11/189 (5%)
Query: 72 IQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEE 131
I+ +E + G R A+ AC + + LL G + L + G T LHL + S +
Sbjct: 30 IRQGAELDARVGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQ 89
Query: 132 CVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHY 191
C KLLL+ GA N ++ E++ TPLH AA+ V + + HGADV S
Sbjct: 90 CAKLLLEAGATVNL--AAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALN 147
Query: 192 AVLSDA---------PEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
A + A + LLEAGA TPLH A + G +LLL GA
Sbjct: 148 AACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGA 207
Query: 243 DVRAAMGPG 251
G G
Sbjct: 208 RAEVPNGAG 216
Score = 53.6 bits (123), Expect = 2e-06
Identities = 35/101 (34%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 281 PNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLL 340
P + PL +AT + L+ + A++ A+ GR LH A R C RLLL
Sbjct: 6 PKTKQTAPLAIATARGYTDCARHLIRQGAELDAR-VGGRAALHEACARAQFDC--VRLLL 62
Query: 341 SAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
+ GA N G TPLH+ + E C LLL+ G V L
Sbjct: 63 TFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNL 103
>AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated
transcript 8 BAT8 isoform a variant protein.
Length = 1031
Score = 101 bits (242), Expect = 9e-21
Identities = 79/243 (32%), Positives = 117/243 (48%), Gaps = 11/243 (4%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L+LS G + V L+L PN + S ++K TPLH AA S+ VL+ GA++N
Sbjct: 468 LYLSVKQGELQKVILMLLDNLDPN-FQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANIN 526
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
A R+PL AV+++ EV + +++ G C + + T LH AA +G+ LLL+
Sbjct: 527 AVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLS 586
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-------TPLHLA 292
G A G T + AAE H E R+LL GA + + + LH A
Sbjct: 587 TGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNVSERLVEEENICLHWA 646
Query: 293 TLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNF 352
+ S + E+L++ D+ A + G TPLH A C + L LS GA+P +
Sbjct: 647 SFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVL--LFLSRGANPELRNKE 704
Query: 353 GYT 355
G T
Sbjct: 705 GDT 707
Score = 91.1 bits (216), Expect = 1e-17
Identities = 73/214 (34%), Positives = 102/214 (47%), Gaps = 11/214 (5%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
S R+PLH A + E+ LL+AGA + TPL A + ++ G
Sbjct: 498 SKRTPLHAAAQKGSVEICHVLLQAGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGC 557
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHG-AHIDWPNFRGQTPLHLATLAQSLEVVE 302
V + G +T LH AA+ G+ E LLL G ++ + G TP+ A + +EV+
Sbjct: 558 VYSKEEDG-STCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIR 616
Query: 303 MLVDRCADVRAKD-------ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
ML+ R ADV D + LH A G+ A IA +LL+A D +A + G T
Sbjct: 617 MLLTRGADVTLTDNVSERLVEEENICLHWASFTGSAA--IAEVLLNARCDLHAVNYHGDT 674
Query: 356 PLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
PLHIAA + CVLL L G + LR G +A
Sbjct: 675 PLHIAARESYHDCVLLFLSRGANPELRNKEGDTA 708
Score = 63.7 bits (148), Expect = 2e-09
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 13/228 (5%)
Query: 103 LLKMGVDPDELDD--AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCA 160
+L +DP+ D + RT LH + GS E +LL GA+ N D + + TPL A
Sbjct: 483 MLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANINAVD---KQQRTPLMEA 539
Query: 161 ASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPEVVKELLEAGACPDTPQVFTE 219
L + ++ G V + D S LH+A E+V LL G Q
Sbjct: 540 VVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDVNAQDSGG 599
Query: 220 -TPLHVAASLGSASCTKLLLNAGADVRAA------MGPGKATALHLAAEDGHAECARLLL 272
TP+ AA ++LL GADV + + LH A+ G A A +LL
Sbjct: 600 WTPIIWAAEHKHIEVIRMLLTRGADVTLTDNVSERLVEEENICLHWASFTGSAAIAEVLL 659
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
+ + N+ G TPLH+A + V + + R A+ ++ +G T
Sbjct: 660 NARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDT 707
Score = 44.4 bits (100), Expect = 0.001
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Query: 299 EVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V+ ML+D + ++ RTPLH A +G+ +I +LL AGA+ NA D TPL
Sbjct: 479 KVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGS--VEICHVLLQAGANINAVDKQQRTPL 536
Query: 358 HIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A +N ++ GG V + G + L
Sbjct: 537 MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCL 569
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/63 (28%), Positives = 29/63 (46%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
WA + G + + LL D ++ G T LH++ +CV L L GA+P +
Sbjct: 645 WASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKE 704
Query: 150 TET 152
+T
Sbjct: 705 GDT 707
>BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 35
protein.
Length = 1001
Score = 100 bits (240), Expect = 2e-20
Identities = 69/187 (36%), Positives = 96/187 (51%), Gaps = 5/187 (2%)
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPE 199
A P DS+ ++ P H AAS C+ +L+A+GAD+N+ D S LH A +S P+
Sbjct: 45 ARPTKLDSNGQS---PFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQ 101
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
VK LL+ GA D +PLH AAS G AS LL + A + G+ T L +A
Sbjct: 102 CVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGR-TPLMIA 160
Query: 260 AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR 319
+ GHA LL GA ++ + ++ L LA S EV E+L+ AD A D+ G
Sbjct: 161 SLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGH 220
Query: 320 TPLHGAI 326
LH A+
Sbjct: 221 DALHYAL 227
Score = 98.7 bits (235), Expect = 7e-20
Identities = 72/188 (38%), Positives = 92/188 (48%), Gaps = 5/188 (2%)
Query: 110 PDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACV 169
P +LD G++ HL+ G EC+ +LL +GA N S E +T LH A + CV
Sbjct: 47 PTKLDSNGQSPFHLAASKGLTECLTILLANGADIN---SKNEDGSTALHLATISCQPQCV 103
Query: 170 KVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASL 228
KVL+ HGA+ +A +RSPLH+A S V L + A D TPL +A+
Sbjct: 104 KVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLG 163
Query: 229 GSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTP 288
G A+ LL GA V K +AL LA E G AE A LLL HGA + G
Sbjct: 164 GHAAICSQLLQRGARVNVTDKNDK-SALILACEKGSAEVAELLLSHGADAGAVDSTGHDA 222
Query: 289 LHLATLAQ 296
LH A Q
Sbjct: 223 LHYALHTQ 230
Score = 90.6 bits (215), Expect = 2e-17
Identities = 63/187 (33%), Positives = 90/187 (48%), Gaps = 3/187 (1%)
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
++P H+AAS G C +LL GAD+ + G +TALHLA +C ++LL HGA+
Sbjct: 55 QSPFHLAASKGLTECLTILLANGADINSKNEDG-STALHLATISCQPQCVKVLLQHGANE 113
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
D + ++PLH A + V +L D A + D DGRTPL A + G A I
Sbjct: 114 DAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAA--ICSQ 171
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL GA N D + L +A + LLL +G D + G AL + +
Sbjct: 172 LLQRGARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYALHTQD 231
Query: 399 DVIPRYL 405
+ R+L
Sbjct: 232 KALWRHL 238
Score = 78.2 bits (184), Expect = 1e-13
Identities = 55/158 (34%), Positives = 82/158 (51%), Gaps = 5/158 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + ++ G T LHL+ + +CVK+LL HGA+ + D+ +PLH AAS
Sbjct: 73 LLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENR---SPLHWAAS 129
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ + V +L H A ++ +D R+PL A L + +LL+ GA + ++
Sbjct: 130 SGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSA 189
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
L +A GSA +LLL+ GAD A G ALH A
Sbjct: 190 LILACEKGSAEVAELLLSHGADAGAVDSTGH-DALHYA 226
Score = 60.5 bits (140), Expect = 2e-08
Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Query: 285 GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGA 344
GQ+P HLA E + +L+ AD+ +K+ DG T LH A + C ++LL GA
Sbjct: 54 GQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQC--VKVLLQHGA 111
Query: 345 DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ +A D +PLH AA + ++ VLLL D+ + + N G + L
Sbjct: 112 NEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPL 157
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R+ + WA G + + L D LD+ GRT L ++ L G LL GA N
Sbjct: 121 RSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVN 180
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D + + A L C + +A ++L++HGAD A + LHYA+ + + +
Sbjct: 181 VTDKN-DKSALILACEKGSAEVA--ELLLSHGADAGAVDSTGHDALHYALHTQDKALWRH 237
Query: 204 LLEA 207
L +A
Sbjct: 238 LQQA 241
Score = 38.3 bits (85), Expect = 0.098
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A L A P D+ G +P H+AA + C+ +LL G D+ + G +AL
Sbjct: 36 VAALASRKSARPTKLDSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTAL 91
>BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 35
protein.
Length = 1001
Score = 100 bits (240), Expect = 2e-20
Identities = 69/187 (36%), Positives = 96/187 (51%), Gaps = 5/187 (2%)
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPE 199
A P DS+ ++ P H AAS C+ +L+A+GAD+N+ D S LH A +S P+
Sbjct: 45 ARPTKLDSNGQS---PFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQ 101
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
VK LL+ GA D +PLH AAS G AS LL + A + G+ T L +A
Sbjct: 102 CVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGR-TPLMIA 160
Query: 260 AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR 319
+ GHA LL GA ++ + ++ L LA S EV E+L+ AD A D+ G
Sbjct: 161 SLGGHAAICSQLLQRGARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGH 220
Query: 320 TPLHGAI 326
LH A+
Sbjct: 221 DALHYAL 227
Score = 98.7 bits (235), Expect = 7e-20
Identities = 72/188 (38%), Positives = 92/188 (48%), Gaps = 5/188 (2%)
Query: 110 PDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACV 169
P +LD G++ HL+ G EC+ +LL +GA N S E +T LH A + CV
Sbjct: 47 PTKLDSNGQSPFHLAASKGLTECLTILLANGADIN---SKNEDGSTALHLATISCQPQCV 103
Query: 170 KVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASL 228
KVL+ HGA+ +A +RSPLH+A S V L + A D TPL +A+
Sbjct: 104 KVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLG 163
Query: 229 GSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTP 288
G A+ LL GA V K +AL LA E G AE A LLL HGA + G
Sbjct: 164 GHAAICSQLLQRGARVNVTDKNDK-SALILACEKGSAEVAELLLSHGADAGAVDSTGHDA 222
Query: 289 LHLATLAQ 296
LH A Q
Sbjct: 223 LHYALHTQ 230
Score = 90.6 bits (215), Expect = 2e-17
Identities = 63/187 (33%), Positives = 90/187 (48%), Gaps = 3/187 (1%)
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
++P H+AAS G C +LL GAD+ + G +TALHLA +C ++LL HGA+
Sbjct: 55 QSPFHLAASKGLTECLTILLANGADINSKNEDG-STALHLATISCQPQCVKVLLQHGANE 113
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
D + ++PLH A + V +L D A + D DGRTPL A + G A I
Sbjct: 114 DAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAA--ICSQ 171
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL GA N D + L +A + LLL +G D + G AL + +
Sbjct: 172 LLQRGARVNVTDKNDKSALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYALHTQD 231
Query: 399 DVIPRYL 405
+ R+L
Sbjct: 232 KALWRHL 238
Score = 78.2 bits (184), Expect = 1e-13
Identities = 55/158 (34%), Positives = 82/158 (51%), Gaps = 5/158 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + ++ G T LHL+ + +CVK+LL HGA+ + D+ +PLH AAS
Sbjct: 73 LLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENR---SPLHWAAS 129
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ + V +L H A ++ +D R+PL A L + +LL+ GA + ++
Sbjct: 130 SGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKSA 189
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
L +A GSA +LLL+ GAD A G ALH A
Sbjct: 190 LILACEKGSAEVAELLLSHGADAGAVDSTGH-DALHYA 226
Score = 60.5 bits (140), Expect = 2e-08
Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Query: 285 GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGA 344
GQ+P HLA E + +L+ AD+ +K+ DG T LH A + C ++LL GA
Sbjct: 54 GQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQC--VKVLLQHGA 111
Query: 345 DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ +A D +PLH AA + ++ VLLL D+ + + N G + L
Sbjct: 112 NEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPL 157
Score = 44.8 bits (101), Expect = 0.001
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R+ + WA G + + L D LD+ GRT L ++ L G LL GA N
Sbjct: 121 RSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVN 180
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D + + A L C + +A ++L++HGAD A + LHYA+ + + +
Sbjct: 181 VTDKN-DKSALILACEKGSAEVA--ELLLSHGADAGAVDSTGHDALHYALHTQDKALWRH 237
Query: 204 LLEA 207
L +A
Sbjct: 238 LQQA 241
Score = 38.3 bits (85), Expect = 0.098
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A L A P D+ G +P H+AA + C+ +LL G D+ + G +AL
Sbjct: 36 VAALASRKSARPTKLDSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTAL 91
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 100 bits (240), Expect = 2e-20
Identities = 83/271 (30%), Positives = 125/271 (46%), Gaps = 15/271 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 204 TALHLAVYKDNAELITSLLHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 263
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 264 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 319
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 320 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLAC 379
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 380 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 439
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPN 347
DG T LH A G + + LL GAD N
Sbjct: 440 DGHTGLHSACYHG--HIRLVQFLLDNGADMN 468
Score = 97.5 bits (232), Expect = 2e-19
Identities = 88/297 (29%), Positives = 126/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 180 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADVQQVGYG---GL 236
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 237 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 294
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 295 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDIVK 353
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 354 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 413
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D+ L
Sbjct: 414 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNL 469
Score = 88.2 bits (209), Expect = 9e-17
Identities = 74/252 (29%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 168 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 224
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GADV G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 225 GADVQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 284
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 285 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 343
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 344 SRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 401
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 402 ENIFSETAFHSA 413
Score = 85.4 bits (202), Expect = 7e-16
Identities = 59/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA + + G T LH+AT+A LE ++L+ A+V
Sbjct: 204 TALHLAVYKDNAELITSLLHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 263
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 264 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 321
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R I +YL + D
Sbjct: 322 EEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSD 359
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/245 (29%), Positives = 109/245 (44%), Gaps = 11/245 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 232 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 291
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 292 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 348
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 349 HDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 408
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 409 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 468
Query: 313 AKDAD 317
D
Sbjct: 469 LVACD 473
Score = 37.1 bits (82), Expect = 0.23
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 167 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 225
Query: 377 GDVTLRTNGGVSAL 390
DV GG++AL
Sbjct: 226 ADVQQVGYGGLTAL 239
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 100 bits (239), Expect = 2e-20
Identities = 83/271 (30%), Positives = 125/271 (46%), Gaps = 15/271 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 163 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 218
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLAC 278
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 338
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPN 347
DG T LH A G + + LL GAD N
Sbjct: 339 DGHTGLHSACYHG--HIRLVQFLLDNGADMN 367
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/297 (29%), Positives = 126/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 79 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG---GL 135
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 136 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDIVK 252
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 253 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D+ L
Sbjct: 313 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNL 368
Score = 87.8 bits (208), Expect = 1e-16
Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 67 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 123
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GAD+ G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 124 GADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 183
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 184 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 242
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 243 SRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 300
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 301 ENIFSETAFHSA 312
Score = 85.8 bits (203), Expect = 5e-16
Identities = 60/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA I + G T LH+AT+A LE ++L+ A+V
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 163 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R I +YL + D
Sbjct: 221 EEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSD 258
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/245 (29%), Positives = 109/245 (44%), Gaps = 11/245 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 131 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 190
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 191 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 247
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 248 HDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 307
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 308 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
Query: 313 AKDAD 317
D
Sbjct: 368 LVACD 372
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 66 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 377 GDVTLRTNGGVSAL 390
D+ GG++AL
Sbjct: 125 ADIQQVGYGGLTAL 138
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 100 bits (239), Expect = 2e-20
Identities = 83/271 (30%), Positives = 125/271 (46%), Gaps = 15/271 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 163 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 218
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLAC 278
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 338
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPN 347
DG T LH A G + + LL GAD N
Sbjct: 339 DGHTGLHSACYHG--HIRLVQFLLDNGADMN 367
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/297 (29%), Positives = 126/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 79 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG---GL 135
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 136 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDIVK 252
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 253 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D+ L
Sbjct: 313 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNL 368
Score = 87.8 bits (208), Expect = 1e-16
Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 67 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 123
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GAD+ G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 124 GADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 183
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 184 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 242
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 243 SRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 300
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 301 ENIFSETAFHSA 312
Score = 85.8 bits (203), Expect = 5e-16
Identities = 60/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA I + G T LH+AT+A LE ++L+ A+V
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 163 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R I +YL + D
Sbjct: 221 EEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSD 258
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/245 (29%), Positives = 109/245 (44%), Gaps = 11/245 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 131 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 190
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 191 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 247
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 248 HDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 307
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 308 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
Query: 313 AKDAD 317
D
Sbjct: 368 LVACD 372
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 66 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 377 GDVTLRTNGGVSAL 390
D+ GG++AL
Sbjct: 125 ADIQQVGYGGLTAL 138
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 100 bits (239), Expect = 2e-20
Identities = 83/271 (30%), Positives = 125/271 (46%), Gaps = 15/271 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 163 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 218
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLAC 278
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 338
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPN 347
DG T LH A G + + LL GAD N
Sbjct: 339 DGHTGLHSACYHG--HIRLVQFLLDNGADMN 367
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/297 (29%), Positives = 126/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 79 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG---GL 135
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 136 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDIVK 252
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 253 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D+ L
Sbjct: 313 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNL 368
Score = 87.8 bits (208), Expect = 1e-16
Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 67 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 123
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GAD+ G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 124 GADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 183
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 184 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 242
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 243 SRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 300
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 301 ENIFSETAFHSA 312
Score = 85.8 bits (203), Expect = 5e-16
Identities = 60/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA I + G T LH+AT+A LE ++L+ A+V
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 163 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R I +YL + D
Sbjct: 221 EEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSD 258
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/245 (29%), Positives = 109/245 (44%), Gaps = 11/245 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 131 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 190
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 191 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 247
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 248 HDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 307
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 308 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
Query: 313 AKDAD 317
D
Sbjct: 368 LVACD 372
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 66 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 377 GDVTLRTNGGVSAL 390
D+ GG++AL
Sbjct: 125 ADIQQVGYGGLTAL 138
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 100 bits (239), Expect = 2e-20
Identities = 83/271 (30%), Positives = 125/271 (46%), Gaps = 15/271 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 163 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 218
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLAC 278
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 338
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPN 347
DG T LH A G + + LL GAD N
Sbjct: 339 DGHTGLHSACYHG--HIRLVQFLLDNGADMN 367
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/297 (29%), Positives = 126/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 79 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG---GL 135
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 136 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDIVK 252
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 253 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D+ L
Sbjct: 313 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNL 368
Score = 87.8 bits (208), Expect = 1e-16
Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 67 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 123
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GAD+ G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 124 GADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 183
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 184 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 242
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 243 SRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 300
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 301 ENIFSETAFHSA 312
Score = 85.8 bits (203), Expect = 5e-16
Identities = 60/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA I + G T LH+AT+A LE ++L+ A+V
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 163 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R I +YL + D
Sbjct: 221 EEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSD 258
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/245 (29%), Positives = 109/245 (44%), Gaps = 11/245 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 131 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 190
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 191 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 247
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 248 HDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 307
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 308 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
Query: 313 AKDAD 317
D
Sbjct: 368 LVACD 372
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 66 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 377 GDVTLRTNGGVSAL 390
D+ GG++AL
Sbjct: 125 ADIQQVGYGGLTAL 138
>BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 100 bits (239), Expect = 2e-20
Identities = 69/208 (33%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Query: 174 AHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC 233
AH AD N DR + A D +V L + G P V + HV S G+ C
Sbjct: 26 AHAADWNK-YDDRL-MKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLEC 83
Query: 234 TKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT 293
+L G D+ + G+ ALHLAA+ GHA C + LL + + + +G+T LH A
Sbjct: 84 LNAILIHGVDITTSDTAGR-NALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAA 142
Query: 294 LAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFG 353
+A +++L D A V AKD DGRTPL + I +LL+ GAD N+ D
Sbjct: 143 MADCPSSIQLLCDHGASVNAKDVDGRTPL--VLATQMSRPTICQLLIDRGADVNSRDKQN 200
Query: 354 YTPLHIAALNEFSACVLLLLDYGGDVTL 381
T L + V +L+ G D++L
Sbjct: 201 RTALMLGCEYGCRDAVEVLIKNGADISL 228
Score = 93.5 bits (222), Expect = 2e-18
Identities = 60/203 (29%), Positives = 101/203 (49%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K GV+P +LD GR+ H+ G+ EC+ +L HG T D++ LH AA
Sbjct: 54 LAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNA---LHLAAK 110
Query: 163 AKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
C++ L+ + +A L R+ LH A ++D P ++ L + GA + V TP
Sbjct: 111 YGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTP 170
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L +A + + +LL++ GADV + + TAL L E G + +L+ +GA I
Sbjct: 171 LVLATQMSRPTICQLLIDRGADVNSRDKQNR-TALMLGCEYGCRDAVEVLIKNGADISLL 229
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G + A + +L+++ +L
Sbjct: 230 DALGHDSSYYARIGDNLDILTLL 252
Score = 68.5 bits (160), Expect = 8e-11
Identities = 60/219 (27%), Positives = 96/219 (43%), Gaps = 7/219 (3%)
Query: 130 EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSDRSP 188
E+ +L G +P D E ++ H S +L C+ ++ HG D+ + R+
Sbjct: 48 EKVTSILAKKGVNPGKLD--VEGRSV-FHVVTSKGNLECLNAILIHGVDITTSDTAGRNA 104
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH A +++LL+ + + T LH AA S +LL + GA V A
Sbjct: 105 LHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKD 164
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G+ T L LA + +LL+D GA ++ + + +T L L + VE+L+
Sbjct: 165 VDGR-TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNG 223
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
AD+ DA G + A R DI LL +A + N
Sbjct: 224 ADISLLDALGHDSSYYA--RIGDNLDILTLLKTASENTN 260
Score = 61.7 bits (143), Expect = 9e-09
Identities = 46/138 (33%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT-LAQSLEVVEMLVDRCADVR 312
+ H+ G+ EC +L HG I + G+ LHLA +L + ++L C
Sbjct: 70 SVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 129
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D GRT LH A + A +LL GA NA D G TPL +A LL
Sbjct: 130 A-DLQGRTALHDAAM--ADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLL 186
Query: 373 LDYGGDVTLRTNGGVSAL 390
+D G DV R +AL
Sbjct: 187 IDRGADVNSRDKQNRTAL 204
Score = 52.0 bits (119), Expect = 7e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R A+ A G ++ L KLL+ + D GRT LH + + ++LL DHGA N
Sbjct: 102 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVN 161
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D TPL A ++LI GADVN+ +R+ L + V+
Sbjct: 162 AKDVDGR---TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEV 218
Query: 204 LLEAGA 209
L++ GA
Sbjct: 219 LIKNGA 224
Score = 35.1 bits (77), Expect = 0.92
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT ++ A + + + L+ G D + D RT L L C G + V++L+ +GA +
Sbjct: 168 RTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADIS 227
Query: 145 TWDS 148
D+
Sbjct: 228 LLDA 231
>BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 100 bits (239), Expect = 2e-20
Identities = 69/208 (33%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Query: 174 AHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC 233
AH AD N DR + A D +V L + G P V + HV S G+ C
Sbjct: 26 AHAADWNK-YDDRL-MKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLEC 83
Query: 234 TKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT 293
+L G D+ + G+ ALHLAA+ GHA C + LL + + + +G+T LH A
Sbjct: 84 LNAILIHGVDITTSDTAGR-NALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAA 142
Query: 294 LAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFG 353
+A +++L D A V AKD DGRTPL + I +LL+ GAD N+ D
Sbjct: 143 MADCPSSIQLLCDHGASVNAKDVDGRTPL--VLATQMSRPTICQLLIDRGADVNSRDKQN 200
Query: 354 YTPLHIAALNEFSACVLLLLDYGGDVTL 381
T L + V +L+ G D++L
Sbjct: 201 RTALMLGCEYGCRDAVEVLIKNGADISL 228
Score = 93.5 bits (222), Expect = 2e-18
Identities = 60/203 (29%), Positives = 101/203 (49%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K GV+P +LD GR+ H+ G+ EC+ +L HG T D++ LH AA
Sbjct: 54 LAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNA---LHLAAK 110
Query: 163 AKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
C++ L+ + +A L R+ LH A ++D P ++ L + GA + V TP
Sbjct: 111 YGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTP 170
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L +A + + +LL++ GADV + + TAL L E G + +L+ +GA I
Sbjct: 171 LVLATQMSRPTICQLLIDRGADVNSRDKQNR-TALMLGCEYGCRDAVEVLIKNGADISLL 229
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G + A + +L+++ +L
Sbjct: 230 DALGHDSSYYARIGDNLDILTLL 252
Score = 68.5 bits (160), Expect = 8e-11
Identities = 60/219 (27%), Positives = 96/219 (43%), Gaps = 7/219 (3%)
Query: 130 EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSDRSP 188
E+ +L G +P D E ++ H S +L C+ ++ HG D+ + R+
Sbjct: 48 EKVTSILAKKGVNPGKLD--VEGRSV-FHVVTSKGNLECLNAILIHGVDITTSDTAGRNA 104
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH A +++LL+ + + T LH AA S +LL + GA V A
Sbjct: 105 LHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKD 164
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G+ T L LA + +LL+D GA ++ + + +T L L + VE+L+
Sbjct: 165 VDGR-TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNG 223
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
AD+ DA G + A R DI LL +A + N
Sbjct: 224 ADISLLDALGHDSSYYA--RIGDNLDILTLLKTASENTN 260
Score = 61.7 bits (143), Expect = 9e-09
Identities = 46/138 (33%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT-LAQSLEVVEMLVDRCADVR 312
+ H+ G+ EC +L HG I + G+ LHLA +L + ++L C
Sbjct: 70 SVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 129
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D GRT LH A + A +LL GA NA D G TPL +A LL
Sbjct: 130 A-DLQGRTALHDAAM--ADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLL 186
Query: 373 LDYGGDVTLRTNGGVSAL 390
+D G DV R +AL
Sbjct: 187 IDRGADVNSRDKQNRTAL 204
Score = 52.0 bits (119), Expect = 7e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R A+ A G ++ L KLL+ + D GRT LH + + ++LL DHGA N
Sbjct: 102 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVN 161
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D TPL A ++LI GADVN+ +R+ L + V+
Sbjct: 162 AKDVDGR---TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEV 218
Query: 204 LLEAGA 209
L++ GA
Sbjct: 219 LIKNGA 224
Score = 35.1 bits (77), Expect = 0.92
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT ++ A + + + L+ G D + D RT L L C G + V++L+ +GA +
Sbjct: 168 RTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADIS 227
Query: 145 TWDS 148
D+
Sbjct: 228 LLDA 231
>BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing 7 protein.
Length = 274
Score = 100 bits (239), Expect = 2e-20
Identities = 79/239 (33%), Positives = 114/239 (47%), Gaps = 15/239 (6%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD--VNAGLSD 185
G V+ +L+ G PN D++ T LH +A+ CV+V + HGAD V +
Sbjct: 25 GDVHTVRKMLEQGYSPNGRDANGWTL---LHFSAARGKERCVRVFLEHGADPTVKDLIGG 81
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE---TPLHVAASLGSASCTKLLLNAGA 242
+ LHYA + + + +LE+ D + TPLHVAA G S +LLL A
Sbjct: 82 FTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKA 141
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+V G T L LA + C ++LLDH A+ID N L A + +
Sbjct: 142 EVDPLSDKG-TTPLQLAIIRERSSCVKILLDHNANIDIQN---GFLLRYAVIKSNHSYCR 197
Query: 303 MLVDRCADVR-AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
M + R AD + DG+TPLH + +R C AR+L + GAD N + G TPL ++
Sbjct: 198 MFLQRGADTNLGRLEDGQTPLHLSALRDDVLC--ARMLYNYGADTNTRNYEGQTPLAVS 254
Score = 92.7 bits (220), Expect = 4e-18
Identities = 72/226 (31%), Positives = 106/226 (46%), Gaps = 11/226 (4%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
K+L+ G P+ D G T LH S G E CV++ L+HGA P D T LH AA
Sbjct: 32 KMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD--LIGGFTALHYAA 89
Query: 162 SAKSLACVKVLI--AHGAD-VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
++++ + +D +NA +D +PLH A V+ LLE A D
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL +A +SC K+LL+ A++ G + + H+ C R+ L GA
Sbjct: 150 GTTPLQLAIIRERSSCVKILLDHNANIDIQNG---FLLRYAVIKSNHSYC-RMFLQRGAD 205
Query: 278 IDWPNFR-GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ GQTPLHL+ L + ML + AD ++ +G+TPL
Sbjct: 206 TNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPL 251
Score = 90.2 bits (214), Expect = 2e-17
Identities = 70/240 (29%), Positives = 111/240 (46%), Gaps = 10/240 (4%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
+ A +A + V+ ++ G N + + LH++ V+ LE GA P
Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77
Query: 216 VFTE-TPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ T LH AA G A +L+L + +D+ A T LH+AA G RLLL
Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLL 137
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+ A +D + +G TPL LA + + V++L+D A++ D L A+++ +
Sbjct: 138 EFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI---DIQNGFLLRYAVIKSNHS 194
Query: 333 CDIARLLLSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R+ L GAD N G TPLH++AL + C +L +YG D R G + L+
Sbjct: 195 --YCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLA 252
Score = 78.6 bits (185), Expect = 8e-14
Identities = 70/251 (27%), Positives = 106/251 (42%), Gaps = 9/251 (3%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
++ H N L + + AV + V+++LE G P+ T LH +A+ G
Sbjct: 1 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE 60
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFR---GQTP 288
C ++ L GAD G TALH AA G A ARL+L+ D N + G TP
Sbjct: 61 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP 120
Query: 289 LHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNA 348
LH+A V +L++ A+V G TPL AI+R +C ++LL A+ +
Sbjct: 121 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSC--VKILLDHNANIDI 178
Query: 349 ADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL-RTNGGVSALSFIVRRVPDVIPRYLCK 407
+ F L A + + + L G D L R G + L R + R L
Sbjct: 179 QNGF---LLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYN 235
Query: 408 FDDAVHVSEHE 418
+ + +E
Sbjct: 236 YGADTNTRNYE 246
Score = 56.4 bits (130), Expect = 3e-07
Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 8/144 (5%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A G+ + LL+ + D L D G T L L+ + CVK+LLDH A+ + +
Sbjct: 124 AAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQNGFL 183
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSD-RSPLHYAVLSDAPEVVKELLEAG 208
L A + + ++ + GAD N G L D ++PLH + L D + L G
Sbjct: 184 ------LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYG 237
Query: 209 ACPDTPQVFTETPLHVAASLGSAS 232
A +T +TPL V+ S+ +S
Sbjct: 238 ADTNTRNYEGQTPLAVSISISGSS 261
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 100 bits (239), Expect = 2e-20
Identities = 83/271 (30%), Positives = 125/271 (46%), Gaps = 15/271 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 163 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 218
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLAC 278
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 338
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPN 347
DG T LH A G + + LL GAD N
Sbjct: 339 DGHTGLHSACYHG--HIRLVQFLLDNGADMN 367
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/297 (29%), Positives = 126/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 79 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG---GL 135
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 136 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDIVK 252
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 253 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D+ L
Sbjct: 313 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNL 368
Score = 87.8 bits (208), Expect = 1e-16
Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 67 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 123
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GAD+ G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 124 GADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 183
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 184 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 242
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 243 SRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 300
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 301 ENIFSETAFHSA 312
Score = 85.8 bits (203), Expect = 5e-16
Identities = 60/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA I + G T LH+AT+A LE ++L+ A+V
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 163 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R I +YL + D
Sbjct: 221 EEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSD 258
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/245 (29%), Positives = 109/245 (44%), Gaps = 11/245 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 131 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 190
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 191 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 247
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 248 HDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 307
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 308 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
Query: 313 AKDAD 317
D
Sbjct: 368 LVACD 372
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 66 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 377 GDVTLRTNGGVSAL 390
D+ GG++AL
Sbjct: 125 ADIQQVGYGGLTAL 138
>AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens
cDNA FLJ33801 fis, clone CTONG2000411. ).
Length = 1001
Score = 100 bits (239), Expect = 2e-20
Identities = 69/187 (36%), Positives = 95/187 (50%), Gaps = 5/187 (2%)
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSP-LHYAVLSDAPE 199
A P DS+ ++ P H AAS C+ +L+A+GAD+N+ D S LH A +S P+
Sbjct: 45 ARPTKLDSNGQS---PFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQ 101
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
VK LL+ GA D +PLH AAS G AS LL + A + G+ T L +A
Sbjct: 102 CVKVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGR-TPLMIA 160
Query: 260 AEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGR 319
+ GHA LL GA ++ + + L LA S EV E+L+ AD A D+ G
Sbjct: 161 SLGGHAAICSQLLQRGARVNVTDKNDKAALILACEKGSAEVAELLLSHGADAGAVDSTGH 220
Query: 320 TPLHGAI 326
LH A+
Sbjct: 221 DALHYAL 227
Score = 99 bits (238), Expect = 3e-20
Identities = 73/188 (38%), Positives = 92/188 (48%), Gaps = 5/188 (2%)
Query: 110 PDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACV 169
P +LD G++ HL+ G EC+ +LL +GA N S E +T LH A + CV
Sbjct: 47 PTKLDSNGQSPFHLAASKGLTECLTILLANGADIN---SKNEDGSTALHLATISCQPQCV 103
Query: 170 KVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASL 228
KVL+ HGA+ +A +RSPLH+A S V L + A D TPL +A+
Sbjct: 104 KVLLQHGANEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLG 163
Query: 229 GSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTP 288
G A+ LL GA V KA AL LA E G AE A LLL HGA + G
Sbjct: 164 GHAAICSQLLQRGARVNVTDKNDKA-ALILACEKGSAEVAELLLSHGADAGAVDSTGHDA 222
Query: 289 LHLATLAQ 296
LH A Q
Sbjct: 223 LHYALHTQ 230
Score = 90.2 bits (214), Expect = 2e-17
Identities = 63/187 (33%), Positives = 89/187 (47%), Gaps = 3/187 (1%)
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
++P H+AAS G C +LL GAD+ + G +TALHLA +C ++LL HGA+
Sbjct: 55 QSPFHLAASKGLTECLTILLANGADINSKNEDG-STALHLATISCQPQCVKVLLQHGANE 113
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
D + ++PLH A + V +L D A + D DGRTPL A + G A I
Sbjct: 114 DAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAA--ICSQ 171
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL GA N D L +A + LLL +G D + G AL + +
Sbjct: 172 LLQRGARVNVTDKNDKAALILACEKGSAEVAELLLSHGADAGAVDSTGHDALHYALHTQD 231
Query: 399 DVIPRYL 405
+ R+L
Sbjct: 232 KALWRHL 238
Score = 77.8 bits (183), Expect = 1e-13
Identities = 55/158 (34%), Positives = 81/158 (51%), Gaps = 5/158 (3%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D + ++ G T LHL+ + +CVK+LL HGA+ + D+ +PLH AAS
Sbjct: 73 LLANGADINSKNEDGSTALHLATISCQPQCVKVLLQHGANEDAVDAENR---SPLHWAAS 129
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ + V +L H A ++ +D R+PL A L + +LL+ GA + +
Sbjct: 130 SGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVNVTDKNDKAA 189
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
L +A GSA +LLL+ GAD A G ALH A
Sbjct: 190 LILACEKGSAEVAELLLSHGADAGAVDSTGH-DALHYA 226
Score = 60.5 bits (140), Expect = 2e-08
Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 2/106 (1%)
Query: 285 GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGA 344
GQ+P HLA E + +L+ AD+ +K+ DG T LH A + C ++LL GA
Sbjct: 54 GQSPFHLAASKGLTECLTILLANGADINSKNEDGSTALHLATISCQPQC--VKVLLQHGA 111
Query: 345 DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ +A D +PLH AA + ++ VLLL D+ + + N G + L
Sbjct: 112 NEDAVDAENRSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPL 157
Score = 44.4 bits (100), Expect = 0.001
Identities = 36/124 (29%), Positives = 57/124 (45%), Gaps = 4/124 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R+ + WA G + + L D LD+ GRT L ++ L G LL GA N
Sbjct: 121 RSPLHWAASSGCASSVLLLCDHEAFLDVLDNDGRTPLMIASLGGHAAICSQLLQRGARVN 180
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D + + A L C + +A ++L++HGAD A + LHYA+ + + +
Sbjct: 181 VTDKN-DKAALILACEKGSAEVA--ELLLSHGADAGAVDSTGHDALHYALHTQDKALWRH 237
Query: 204 LLEA 207
L +A
Sbjct: 238 LQQA 241
Score = 38.3 bits (85), Expect = 0.098
Identities = 18/56 (32%), Positives = 28/56 (50%)
Query: 335 IARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+A L A P D+ G +P H+AA + C+ +LL G D+ + G +AL
Sbjct: 36 VAALASRKSARPTKLDSNGQSPFHLAASKGLTECLTILLANGADINSKNEDGSTAL 91
>AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containing
SOCS box protein 7 protein.
Length = 318
Score = 100 bits (239), Expect = 2e-20
Identities = 79/239 (33%), Positives = 114/239 (47%), Gaps = 15/239 (6%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD--VNAGLSD 185
G V+ +L+ G PN D++ T LH +A+ CV+V + HGAD V +
Sbjct: 25 GDVHTVRKMLEQGYSPNGRDANGWTL---LHFSAARGKERCVRVFLEHGADPTVKDLIGG 81
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE---TPLHVAASLGSASCTKLLLNAGA 242
+ LHYA + + + +LE+ D + TPLHVAA G S +LLL A
Sbjct: 82 FTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKA 141
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+V G T L LA + C ++LLDH A+ID N L A + +
Sbjct: 142 EVDPLSDKG-TTPLQLAIIRERSSCVKILLDHNANIDIQN---GFLLRYAVIKSNHSYCR 197
Query: 303 MLVDRCADVR-AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
M + R AD + DG+TPLH + +R C AR+L + GAD N + G TPL ++
Sbjct: 198 MFLQRGADTNLGRLEDGQTPLHLSALRDDVLC--ARMLYNYGADTNTRNYEGQTPLAVS 254
Score = 92.7 bits (220), Expect = 4e-18
Identities = 72/226 (31%), Positives = 106/226 (46%), Gaps = 11/226 (4%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
K+L+ G P+ D G T LH S G E CV++ L+HGA P D T LH AA
Sbjct: 32 KMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD--LIGGFTALHYAA 89
Query: 162 SAKSLACVKVLI--AHGAD-VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
++++ + +D +NA +D +PLH A V+ LLE A D
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL +A +SC K+LL+ A++ G + + H+ C R+ L GA
Sbjct: 150 GTTPLQLAIIRERSSCVKILLDHNANIDIQNG---FLLRYAVIKSNHSYC-RMFLQRGAD 205
Query: 278 IDWPNFR-GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ GQTPLHL+ L + ML + AD ++ +G+TPL
Sbjct: 206 TNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPL 251
Score = 90.2 bits (214), Expect = 2e-17
Identities = 70/240 (29%), Positives = 111/240 (46%), Gaps = 10/240 (4%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
+ A +A + V+ ++ G N + + LH++ V+ LE GA P
Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77
Query: 216 VFTE-TPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ T LH AA G A +L+L + +D+ A T LH+AA G RLLL
Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLL 137
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+ A +D + +G TPL LA + + V++L+D A++ D L A+++ +
Sbjct: 138 EFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANI---DIQNGFLLRYAVIKSNHS 194
Query: 333 CDIARLLLSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R+ L GAD N G TPLH++AL + C +L +YG D R G + L+
Sbjct: 195 --YCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLA 252
Score = 78.6 bits (185), Expect = 8e-14
Identities = 70/251 (27%), Positives = 106/251 (42%), Gaps = 9/251 (3%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
++ H N L + + AV + V+++LE G P+ T LH +A+ G
Sbjct: 1 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE 60
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFR---GQTP 288
C ++ L GAD G TALH AA G A ARL+L+ D N + G TP
Sbjct: 61 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP 120
Query: 289 LHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNA 348
LH+A V +L++ A+V G TPL AI+R +C ++LL A+ +
Sbjct: 121 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSC--VKILLDHNANIDI 178
Query: 349 ADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL-RTNGGVSALSFIVRRVPDVIPRYLCK 407
+ F L A + + + L G D L R G + L R + R L
Sbjct: 179 QNGF---LLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYN 235
Query: 408 FDDAVHVSEHE 418
+ + +E
Sbjct: 236 YGADTNTRNYE 246
Score = 56.4 bits (130), Expect = 3e-07
Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 8/144 (5%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A G+ + LL+ + D L D G T L L+ + CVK+LLDH A+ + +
Sbjct: 124 AAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNANIDIQNGFL 183
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSD-RSPLHYAVLSDAPEVVKELLEAG 208
L A + + ++ + GAD N G L D ++PLH + L D + L G
Sbjct: 184 ------LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYG 237
Query: 209 ACPDTPQVFTETPLHVAASLGSAS 232
A +T +TPL V+ S+ +S
Sbjct: 238 ADTNTRNYEGQTPLAVSISISGSS 261
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 100 bits (239), Expect = 2e-20
Identities = 83/271 (30%), Positives = 125/271 (46%), Gaps = 15/271 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 163 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 218
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 219 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLAC 278
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 279 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 338
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPN 347
DG T LH A G + + LL GAD N
Sbjct: 339 DGHTGLHSACYHG--HIRLVQFLLDNGADMN 367
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/297 (29%), Positives = 126/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 79 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG---GL 135
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 136 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 193
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 194 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDIVK 252
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 253 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 312
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D+ L
Sbjct: 313 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNL 368
Score = 87.8 bits (208), Expect = 1e-16
Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 67 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 123
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GAD+ G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 124 GADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 183
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 184 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 242
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 243 SRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 300
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 301 ENIFSETAFHSA 312
Score = 85.8 bits (203), Expect = 5e-16
Identities = 60/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA I + G T LH+AT+A LE ++L+ A+V
Sbjct: 103 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 162
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 163 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 220
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R I +YL + D
Sbjct: 221 EEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSD 258
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/245 (29%), Positives = 109/245 (44%), Gaps = 11/245 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 131 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 190
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 191 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 247
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 248 HDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 307
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 308 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
Query: 313 AKDAD 317
D
Sbjct: 368 LVACD 372
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 66 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 124
Query: 377 GDVTLRTNGGVSAL 390
D+ GG++AL
Sbjct: 125 ADIQQVGYGGLTAL 138
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 100 bits (239), Expect = 2e-20
Identities = 83/271 (30%), Positives = 125/271 (46%), Gaps = 15/271 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 209 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 268
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 269 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 324
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 325 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLAC 384
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 385 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 444
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPN 347
DG T LH A G + + LL GAD N
Sbjct: 445 DGHTGLHSACYHG--HIRLVQFLLDNGADMN 473
Score = 97.1 bits (231), Expect = 2e-19
Identities = 88/297 (29%), Positives = 126/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 185 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG---GL 241
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 242 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 299
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 300 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDIVK 358
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 359 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 418
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D+ L
Sbjct: 419 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMNL 474
Score = 87.8 bits (208), Expect = 1e-16
Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 173 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 229
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GAD+ G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 230 GADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 289
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 290 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 348
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 349 SRFGHHDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 406
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 407 ENIFSETAFHSA 418
Score = 85.8 bits (203), Expect = 5e-16
Identities = 60/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA I + G T LH+AT+A LE ++L+ A+V
Sbjct: 209 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 268
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 269 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 326
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R I +YL + D
Sbjct: 327 EEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSD 364
Score = 80.2 bits (189), Expect = 2e-14
Identities = 73/245 (29%), Positives = 109/245 (44%), Gaps = 11/245 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 237 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 296
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 297 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 353
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 354 HDIVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 413
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 414 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 473
Query: 313 AKDAD 317
D
Sbjct: 474 LVACD 478
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 172 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 230
Query: 377 GDVTLRTNGGVSAL 390
D+ GG++AL
Sbjct: 231 ADIQQVGYGGLTAL 244
>AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein.
Length = 1416
Score = 100 bits (239), Expect = 2e-20
Identities = 69/208 (33%), Positives = 98/208 (47%), Gaps = 5/208 (2%)
Query: 174 AHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC 233
AH AD N DR + A D +V L + G P V + HV S G+ C
Sbjct: 26 AHAADWNK-YDDRL-MKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLEC 83
Query: 234 TKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT 293
+L G D+ + G+ ALHLAA+ GHA C + LL + + + +G+T LH A
Sbjct: 84 LNAILIHGVDITTSDTAGR-NALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAA 142
Query: 294 LAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFG 353
+A +++L D A V AKD DGRTPL + I +LL+ GAD N+ D
Sbjct: 143 MADCPSSIQLLCDHGASVNAKDVDGRTPL--VLATQMSRPTICQLLIDRGADVNSRDKQN 200
Query: 354 YTPLHIAALNEFSACVLLLLDYGGDVTL 381
T L + V +L+ G D++L
Sbjct: 201 RTALMLGCEYGCRDAVEVLIKNGADISL 228
Score = 93.5 bits (222), Expect = 2e-18
Identities = 60/203 (29%), Positives = 101/203 (49%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K GV+P +LD GR+ H+ G+ EC+ +L HG T D++ LH AA
Sbjct: 54 LAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNA---LHLAAK 110
Query: 163 AKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
C++ L+ + +A L R+ LH A ++D P ++ L + GA + V TP
Sbjct: 111 YGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTP 170
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L +A + + +LL++ GADV + + TAL L E G + +L+ +GA I
Sbjct: 171 LVLATQMSRPTICQLLIDRGADVNSRDKQNR-TALMLGCEYGCRDAVEVLIKNGADISLL 229
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G + A + +L+++ +L
Sbjct: 230 DALGHDSSYYARIGDNLDILTLL 252
Score = 68.5 bits (160), Expect = 8e-11
Identities = 60/219 (27%), Positives = 96/219 (43%), Gaps = 7/219 (3%)
Query: 130 EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSDRSP 188
E+ +L G +P D E ++ H S +L C+ ++ HG D+ + R+
Sbjct: 48 EKVTSILAKKGVNPGKLD--VEGRSV-FHVVTSKGNLECLNAILIHGVDITTSDTAGRNA 104
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH A +++LL+ + + T LH AA S +LL + GA V A
Sbjct: 105 LHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKD 164
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G+ T L LA + +LL+D GA ++ + + +T L L + VE+L+
Sbjct: 165 VDGR-TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNG 223
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
AD+ DA G + A R DI LL +A + N
Sbjct: 224 ADISLLDALGHDSSYYA--RIGDNLDILTLLKTASENTN 260
Score = 61.7 bits (143), Expect = 9e-09
Identities = 46/138 (33%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT-LAQSLEVVEMLVDRCADVR 312
+ H+ G+ EC +L HG I + G+ LHLA +L + ++L C
Sbjct: 70 SVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 129
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D GRT LH A + A +LL GA NA D G TPL +A LL
Sbjct: 130 A-DLQGRTALHDAAM--ADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLL 186
Query: 373 LDYGGDVTLRTNGGVSAL 390
+D G DV R +AL
Sbjct: 187 IDRGADVNSRDKQNRTAL 204
Score = 52.0 bits (119), Expect = 7e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R A+ A G ++ L KLL+ + D GRT LH + + ++LL DHGA N
Sbjct: 102 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVN 161
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D TPL A ++LI GADVN+ +R+ L + V+
Sbjct: 162 AKDVDGR---TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEV 218
Query: 204 LLEAGA 209
L++ GA
Sbjct: 219 LIKNGA 224
Score = 35.1 bits (77), Expect = 0.92
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT ++ A + + + L+ G D + D RT L L C G + V++L+ +GA +
Sbjct: 168 RTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADIS 227
Query: 145 TWDS 148
D+
Sbjct: 228 LLDA 231
>AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing protein 7 isoform 1 variant protein.
Length = 274
Score = 99 bits (238), Expect = 3e-20
Identities = 79/239 (33%), Positives = 114/239 (47%), Gaps = 15/239 (6%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD--VNAGLSD 185
G V+ +L+ G PN D++ T LH +A+ CV+V + HGAD V +
Sbjct: 25 GDVHTVRKMLEQGYSPNGRDANGWTL---LHFSAARGKERCVRVFLEHGADPTVKDLIGG 81
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE---TPLHVAASLGSASCTKLLLNAGA 242
+ LHYA + + + +LE+ D + TPLHVAA G S +LLL A
Sbjct: 82 FTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKA 141
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+V G T L LA + C ++LLDH A+ID N L A + +
Sbjct: 142 EVDPLSDKG-TTPLQLAIIREKSSCVKILLDHNANIDIQN---GFLLRYAVIKSNHSYCR 197
Query: 303 MLVDRCADVR-AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
M + R AD + DG+TPLH + +R C AR+L + GAD N + G TPL ++
Sbjct: 198 MFLQRGADTNLGRLEDGQTPLHLSALRDDVLC--ARMLYNYGADTNTRNYEGQTPLAVS 254
Score = 93.1 bits (221), Expect = 3e-18
Identities = 72/226 (31%), Positives = 106/226 (46%), Gaps = 11/226 (4%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
K+L+ G P+ D G T LH S G E CV++ L+HGA P D T LH AA
Sbjct: 32 KMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD--LIGGFTALHYAA 89
Query: 162 SAKSLACVKVLI--AHGAD-VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
++++ + +D +NA +D +PLH A V+ LLE A D
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL +A +SC K+LL+ A++ G + + H+ C R+ L GA
Sbjct: 150 GTTPLQLAIIREKSSCVKILLDHNANIDIQNG---FLLRYAVIKSNHSYC-RMFLQRGAD 205
Query: 278 IDWPNFR-GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ GQTPLHL+ L + ML + AD ++ +G+TPL
Sbjct: 206 TNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPL 251
Score = 90.6 bits (215), Expect = 2e-17
Identities = 70/240 (29%), Positives = 111/240 (46%), Gaps = 10/240 (4%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
+ A +A + V+ ++ G N + + LH++ V+ LE GA P
Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77
Query: 216 VFTE-TPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ T LH AA G A +L+L + +D+ A T LH+AA G RLLL
Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLL 137
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+ A +D + +G TPL LA + + V++L+D A++ D L A+++ +
Sbjct: 138 EFKAEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNANI---DIQNGFLLRYAVIKSNHS 194
Query: 333 CDIARLLLSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R+ L GAD N G TPLH++AL + C +L +YG D R G + L+
Sbjct: 195 --YCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLA 252
Score = 78.6 bits (185), Expect = 8e-14
Identities = 70/251 (27%), Positives = 106/251 (42%), Gaps = 9/251 (3%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
++ H N L + + AV + V+++LE G P+ T LH +A+ G
Sbjct: 1 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE 60
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFR---GQTP 288
C ++ L GAD G TALH AA G A ARL+L+ D N + G TP
Sbjct: 61 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP 120
Query: 289 LHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNA 348
LH+A V +L++ A+V G TPL AI+R +C ++LL A+ +
Sbjct: 121 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSC--VKILLDHNANIDI 178
Query: 349 ADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL-RTNGGVSALSFIVRRVPDVIPRYLCK 407
+ F L A + + + L G D L R G + L R + R L
Sbjct: 179 QNGF---LLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYN 235
Query: 408 FDDAVHVSEHE 418
+ + +E
Sbjct: 236 YGADTNTRNYE 246
Score = 56.8 bits (131), Expect = 3e-07
Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 8/144 (5%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A G+ + LL+ + D L D G T L L+ + CVK+LLDH A+ + +
Sbjct: 124 AAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNANIDIQNGFL 183
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSD-RSPLHYAVLSDAPEVVKELLEAG 208
L A + + ++ + GAD N G L D ++PLH + L D + L G
Sbjct: 184 ------LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYG 237
Query: 209 ACPDTPQVFTETPLHVAASLGSAS 232
A +T +TPL V+ S+ +S
Sbjct: 238 ADTNTRNYEGQTPLAVSISISGSS 261
>AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing protein 7 isoform 1 variant protein.
Length = 274
Score = 99 bits (238), Expect = 3e-20
Identities = 79/239 (33%), Positives = 114/239 (47%), Gaps = 15/239 (6%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD--VNAGLSD 185
G V+ +L+ G PN D++ T LH +A+ CV+V + HGAD V +
Sbjct: 25 GDVHTVRKMLEQGYSPNGRDANGWTL---LHFSAARGKERCVRVFLEHGADPTVKDLIGG 81
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE---TPLHVAASLGSASCTKLLLNAGA 242
+ LHYA + + + +LE+ D + TPLHVAA G S +LLL A
Sbjct: 82 FTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKA 141
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+V G T L LA + C ++LLDH A+ID N L A + +
Sbjct: 142 EVDPLSDKG-TTPLQLAIIREKSSCVKILLDHNANIDIQN---GFLLRYAVIKSNHSYCR 197
Query: 303 MLVDRCADVR-AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
M + R AD + DG+TPLH + +R C AR+L + GAD N + G TPL ++
Sbjct: 198 MFLQRGADTNLGRLEDGQTPLHLSALRDDVLC--ARMLYNYGADTNTRNYEGQTPLAVS 254
Score = 93.1 bits (221), Expect = 3e-18
Identities = 72/226 (31%), Positives = 106/226 (46%), Gaps = 11/226 (4%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
K+L+ G P+ D G T LH S G E CV++ L+HGA P D T LH AA
Sbjct: 32 KMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD--LIGGFTALHYAA 89
Query: 162 SAKSLACVKVLI--AHGAD-VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
++++ + +D +NA +D +PLH A V+ LLE A D
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL +A +SC K+LL+ A++ G + + H+ C R+ L GA
Sbjct: 150 GTTPLQLAIIREKSSCVKILLDHNANIDIQNG---FLLRYAVIKSNHSYC-RMFLQRGAD 205
Query: 278 IDWPNFR-GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ GQTPLHL+ L + ML + AD ++ +G+TPL
Sbjct: 206 TNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPL 251
Score = 90.6 bits (215), Expect = 2e-17
Identities = 70/240 (29%), Positives = 111/240 (46%), Gaps = 10/240 (4%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
+ A +A + V+ ++ G N + + LH++ V+ LE GA P
Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77
Query: 216 VFTE-TPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ T LH AA G A +L+L + +D+ A T LH+AA G RLLL
Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLL 137
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+ A +D + +G TPL LA + + V++L+D A++ D L A+++ +
Sbjct: 138 EFKAEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNANI---DIQNGFLLRYAVIKSNHS 194
Query: 333 CDIARLLLSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R+ L GAD N G TPLH++AL + C +L +YG D R G + L+
Sbjct: 195 --YCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLA 252
Score = 78.6 bits (185), Expect = 8e-14
Identities = 70/251 (27%), Positives = 106/251 (42%), Gaps = 9/251 (3%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
++ H N L + + AV + V+++LE G P+ T LH +A+ G
Sbjct: 1 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE 60
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFR---GQTP 288
C ++ L GAD G TALH AA G A ARL+L+ D N + G TP
Sbjct: 61 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP 120
Query: 289 LHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNA 348
LH+A V +L++ A+V G TPL AI+R +C ++LL A+ +
Sbjct: 121 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSC--VKILLDHNANIDI 178
Query: 349 ADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL-RTNGGVSALSFIVRRVPDVIPRYLCK 407
+ F L A + + + L G D L R G + L R + R L
Sbjct: 179 QNGF---LLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYN 235
Query: 408 FDDAVHVSEHE 418
+ + +E
Sbjct: 236 YGADTNTRNYE 246
Score = 56.8 bits (131), Expect = 3e-07
Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 8/144 (5%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A G+ + LL+ + D L D G T L L+ + CVK+LLDH A+ + +
Sbjct: 124 AAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNANIDIQNGFL 183
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSD-RSPLHYAVLSDAPEVVKELLEAG 208
L A + + ++ + GAD N G L D ++PLH + L D + L G
Sbjct: 184 ------LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYG 237
Query: 209 ACPDTPQVFTETPLHVAASLGSAS 232
A +T +TPL V+ S+ +S
Sbjct: 238 ADTNTRNYEGQTPLAVSISISGSS 261
>AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22551 fis, clone HSI00804. ).
Length = 274
Score = 99 bits (238), Expect = 3e-20
Identities = 79/239 (33%), Positives = 114/239 (47%), Gaps = 15/239 (6%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD--VNAGLSD 185
G V+ +L+ G PN D++ T LH +A+ CV+V + HGAD V +
Sbjct: 25 GDVHTVRKMLEQGYSPNGRDANGWTL---LHFSAARGKERCVRVFLEHGADPTVKDLIGG 81
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTE---TPLHVAASLGSASCTKLLLNAGA 242
+ LHYA + + + +LE+ D + TPLHVAA G S +LLL A
Sbjct: 82 FTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKA 141
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+V G T L LA + C ++LLDH A+ID N L A + +
Sbjct: 142 EVDPLSDKG-TTPLQLAIIREKSSCVKILLDHNANIDIQN---GFLLRYAVIKSNHSYCR 197
Query: 303 MLVDRCADVR-AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
M + R AD + DG+TPLH + +R C AR+L + GAD N + G TPL ++
Sbjct: 198 MFLQRGADTNLGRLEDGQTPLHLSALRDDVLC--ARMLYNYGADTNTRNYEGQTPLAVS 254
Score = 93.1 bits (221), Expect = 3e-18
Identities = 72/226 (31%), Positives = 106/226 (46%), Gaps = 11/226 (4%)
Query: 102 KLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAA 161
K+L+ G P+ D G T LH S G E CV++ L+HGA P D T LH AA
Sbjct: 32 KMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD--LIGGFTALHYAA 89
Query: 162 SAKSLACVKVLI--AHGAD-VNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVF 217
++++ + +D +NA +D +PLH A V+ LLE A D
Sbjct: 90 MHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFKAEVDPLSDK 149
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
TPL +A +SC K+LL+ A++ G + + H+ C R+ L GA
Sbjct: 150 GTTPLQLAIIREKSSCVKILLDHNANIDIQNG---FLLRYAVIKSNHSYC-RMFLQRGAD 205
Query: 278 IDWPNFR-GQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
+ GQTPLHL+ L + ML + AD ++ +G+TPL
Sbjct: 206 TNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPL 251
Score = 90.6 bits (215), Expect = 2e-17
Identities = 70/240 (29%), Positives = 111/240 (46%), Gaps = 10/240 (4%)
Query: 157 LHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQ 215
+ A +A + V+ ++ G N + + LH++ V+ LE GA P
Sbjct: 18 IQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKD 77
Query: 216 VFTE-TPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ T LH AA G A +L+L + +D+ A T LH+AA G RLLL
Sbjct: 78 LIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLL 137
Query: 273 DHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARA 332
+ A +D + +G TPL LA + + V++L+D A++ D L A+++ +
Sbjct: 138 EFKAEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNANI---DIQNGFLLRYAVIKSNHS 194
Query: 333 CDIARLLLSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALS 391
R+ L GAD N G TPLH++AL + C +L +YG D R G + L+
Sbjct: 195 --YCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNYEGQTPLA 252
Score = 78.6 bits (185), Expect = 8e-14
Identities = 70/251 (27%), Positives = 106/251 (42%), Gaps = 9/251 (3%)
Query: 172 LIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSA 231
++ H N L + + AV + V+++LE G P+ T LH +A+ G
Sbjct: 1 MLHHHCRRNPELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKE 60
Query: 232 SCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFR---GQTP 288
C ++ L GAD G TALH AA G A ARL+L+ D N + G TP
Sbjct: 61 RCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTP 120
Query: 289 LHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNA 348
LH+A V +L++ A+V G TPL AI+R +C ++LL A+ +
Sbjct: 121 LHVAAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSC--VKILLDHNANIDI 178
Query: 349 ADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL-RTNGGVSALSFIVRRVPDVIPRYLCK 407
+ F L A + + + L G D L R G + L R + R L
Sbjct: 179 QNGF---LLRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYN 235
Query: 408 FDDAVHVSEHE 418
+ + +E
Sbjct: 236 YGADTNTRNYE 246
Score = 56.8 bits (131), Expect = 3e-07
Identities = 43/144 (29%), Positives = 67/144 (46%), Gaps = 8/144 (5%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
A G+ + LL+ + D L D G T L L+ + CVK+LLDH A+ + +
Sbjct: 124 AAHYGRDSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNANIDIQNGFL 183
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSD-RSPLHYAVLSDAPEVVKELLEAG 208
L A + + ++ + GAD N G L D ++PLH + L D + L G
Sbjct: 184 ------LRYAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYG 237
Query: 209 ACPDTPQVFTETPLHVAASLGSAS 232
A +T +TPL V+ S+ +S
Sbjct: 238 ADTNTRNYEGQTPLAVSISISGSS 261
>BX537853-1|CAD97861.1| 302|Homo sapiens hypothetical protein
protein.
Length = 302
Score = 99.5 bits (237), Expect = 4e-20
Identities = 73/210 (34%), Positives = 100/210 (47%), Gaps = 5/210 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G+ + L L+ GV+ + + + LH +CL G C K LL++GAH N T A
Sbjct: 55 GRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAHVN---GVTVHGA 111
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTP 214
TPL A + S ACV VL+ GA + SP+H AV E ++ LL D
Sbjct: 112 TPLFNACCSGSAACVNVLLEFGAKAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHE 171
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH 274
TPL+VA + C K LL GA V G T LH AA + E LL D+
Sbjct: 172 VPQLGTPLYVACTYQRVDCVKKLLELGASV--DHGQWLDTPLHAAARQSNVEVIHLLTDY 229
Query: 275 GAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
GA++ N +G++ L LA S+E +L
Sbjct: 230 GANLKRRNAQGKSALDLAAPKSSVEQALLL 259
Score = 93.1 bits (221), Expect = 3e-18
Identities = 78/231 (33%), Positives = 112/231 (48%), Gaps = 8/231 (3%)
Query: 144 NTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVK 202
+T+ +PLH AA+ L +K LIA G +VN +R S LH A L K
Sbjct: 35 HTFQGDCRADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAK 94
Query: 203 ELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAED 262
LLE GA + V TPL A GSA+C +LL GA +A + A+ +H A +
Sbjct: 95 ALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGA--KAQLEVHLASPIHEAVKR 152
Query: 263 GHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTP 321
GH EC +LL + +ID + TPL++A Q ++ V+ L++ A V + D TP
Sbjct: 153 GHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TP 210
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
LH A R + ++ LL GA+ + G + L +AA LLL
Sbjct: 211 LHAA-ARQSNV-EVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLL 259
Score = 75.4 bits (177), Expect = 7e-13
Identities = 51/160 (31%), Positives = 78/160 (48%), Gaps = 4/160 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
+PLH AA+ G K L+ G +V + ++LH A GH CA+ LL++GAH++
Sbjct: 46 SPLHEAAAQGRLLALKTLIAQGVNVNLVT-INRVSSLHEACLGGHVACAKALLENGAHVN 104
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
G TPL A + S V +L++ A + + +P+H A+ RG R C L
Sbjct: 105 GVTVHGATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEILLA 163
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+ D + G TPL++A + CV LL+ G V
Sbjct: 164 NNVNID-HEVPQLG-TPLYVACTYQRVDCVKKLLELGASV 201
Score = 73.7 bits (173), Expect = 2e-12
Identities = 64/207 (30%), Positives = 88/207 (42%), Gaps = 5/207 (2%)
Query: 184 SDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD 243
+DRSPLH A +K L+ G + + + LH A G +C K LL GA
Sbjct: 43 ADRSPLHEAAAQGRLLALKTLIAQGVNVNLVTINRVSSLHEACLGGHVACAKALLENGAH 102
Query: 244 VRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEM 303
V G AT L A G A C +LL+ GA +P+H A E +E+
Sbjct: 103 VNGVTVHG-ATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASPIHEAVKRGHRECMEI 160
Query: 304 LVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN 363
L+ ++ + TPL+ A + D + LL GA + TPLH AA
Sbjct: 161 LLANNVNIDHEVPQLGTPLYVACTY--QRVDCVKKLLELGASVDHGQWLD-TPLHAAARQ 217
Query: 364 EFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ LL DYG ++ R G SAL
Sbjct: 218 SNVEVIHLLTDYGANLKRRNAQGKSAL 244
Score = 48.8 bits (111), Expect = 7e-05
Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 5/156 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + AC G + + LL+ G +L+ + +H + G EC+++LL + +
Sbjct: 112 TPLFNACCSGSAACVNVLLEFGAKA-QLEVHLASPIHEAVKRGHRECMEILLANNVNI-- 168
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D TPL+ A + + + CVK L+ GA V+ G +PLH A EV+ L
Sbjct: 169 -DHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLT 227
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG 241
+ GA ++ L +AA S LLL G
Sbjct: 228 DYGANLKRRNAQGKSALDLAAPKSSVE-QALLLREG 262
Score = 33.9 bits (74), Expect = 2.1
Identities = 31/109 (28%), Positives = 54/109 (49%), Gaps = 6/109 (5%)
Query: 72 IQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPD-ELDDAGRTCLHLSCLVGSE 130
++F ++A+ L + I A G + LL V+ D E+ G T L+++C
Sbjct: 130 LEFGAKAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQLG-TPLYVACTYQRV 188
Query: 131 ECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADV 179
+CVK LL+ GA + + TPLH AA ++ + +L +GA++
Sbjct: 189 DCVKKLLELGASVD----HGQWLDTPLHAAARQSNVEVIHLLTDYGANL 233
>BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS
box-containing 2 protein.
Length = 587
Score = 99.5 bits (237), Expect = 4e-20
Identities = 82/276 (29%), Positives = 124/276 (44%), Gaps = 9/276 (3%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI-AHGADVNAG-LSD 185
G EE +K ++ G N + + E PLH AA + C+KVL A+ ++ L +
Sbjct: 68 GDEEALKTMIKEGK--NLAEPNKEGWL-PLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQE 124
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
+ ++ A + + LL+AGA PD ETPL+ A +A K+L+ AD
Sbjct: 125 ETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTN 184
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G TALH + E ++L+ GA ++ N G TPL +A + LE + L
Sbjct: 185 HRCNRGW-TALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLA 243
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
AD+ + +D + L+ A ++ LLS GAD N + G PLHIA+
Sbjct: 244 KYGADINTQASDNASALYEACKNEHE--EVVEFLLSQGADANKTNKDGLLPLHIASKKGN 301
Query: 366 SACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
V +LL +R GVS L R D +
Sbjct: 302 YRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEV 336
Score = 92.7 bits (220), Expect = 4e-18
Identities = 63/208 (30%), Positives = 97/208 (46%), Gaps = 2/208 (0%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
L+ PL A+ E +K +++ G P PLH AA G C K+L A
Sbjct: 55 LAPADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYP 114
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+ TA++LA GH +C LL GA D N +TPL+ A ++ E V+
Sbjct: 115 GTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVK 174
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
+LV AD + G T LH ++ R ++ ++L+S GA + + +G TPL +AA
Sbjct: 175 ILVQHNADTNHRCNRGWTALHESVSR--NDLEVMQILVSGGAKVESKNAYGITPLFVAAQ 232
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ + L YG D+ + + SAL
Sbjct: 233 SGQLEALRFLAKYGADINTQASDNASAL 260
Score = 87.8 bits (208), Expect = 1e-16
Identities = 82/286 (28%), Positives = 126/286 (44%), Gaps = 7/286 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G L ++K G + E + G LH + G C+K+L A+P T D T +
Sbjct: 68 GDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVL--QRAYPGTIDQRTLQEE 125
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
T ++ A L C+ L+ GA+ + R +PL+ A E VK L++ A +
Sbjct: 126 TAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNH 185
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
T LH + S ++L++ GA V + G T L +AA+ G E R L
Sbjct: 186 RCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG-ITPLFVAAQSGQLEALRFLAK 244
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+GA I+ + L+ A + EVVE L+ + AD + DG PLH A +G
Sbjct: 245 YGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYR- 303
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
I ++LL + + G +PLH+AA + LL DV
Sbjct: 304 -IVQMLLPVTSRTRIRRS-GVSPLHLAAERNHDEVLEALLSARFDV 347
Score = 80.2 bits (189), Expect = 2e-14
Identities = 84/302 (27%), Positives = 131/302 (43%), Gaps = 16/302 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G L LL+ G +PD + + T L+ +C + E VK+L+ H A N
Sbjct: 126 TAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTN- 184
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
T LH + S L +++L++ GA V + +PL A S E ++ L
Sbjct: 185 --HRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFL 242
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
+ GA +T + L+ A + LL+ GAD G LH+A++ G+
Sbjct: 243 AKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDG-LLPLHIASKKGN 301
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH- 323
++LL + G +PLHLA EV+E L+ DV A R L+
Sbjct: 302 YRIVQMLLPVTSRTRIRR-SGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYE 360
Query: 324 ----GAIVRGARACDI--ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
A+ ++ LLL GADPN +PL +A + + LLLD+G
Sbjct: 361 DRRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVAIRHGCLRTMQLLLDHGA 417
Query: 378 DV 379
++
Sbjct: 418 NI 419
Score = 78.2 bits (184), Expect = 1e-13
Identities = 71/239 (29%), Positives = 100/239 (41%), Gaps = 5/239 (2%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEA-GACP 211
A PL A +K +I G ++ PLH A +K L A
Sbjct: 58 ADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTI 117
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
D + ET +++A G C LL AGA+ + + T L+ A E +AE ++L
Sbjct: 118 DQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDIS-NKSRETPLYKACERKNAEAVKIL 176
Query: 272 LDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGAR 331
+ H A + RG T LH + LEV+++LV A V +K+A G TPL A G
Sbjct: 177 VQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSG-- 234
Query: 332 ACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ R L GAD N + + L+ A NE V LL G D G+ L
Sbjct: 235 QLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPL 293
Score = 66.1 bits (154), Expect = 4e-10
Identities = 67/252 (26%), Positives = 108/252 (42%), Gaps = 16/252 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+ G + + G T L ++ G E ++ L +GA NT S A+ L+ A
Sbjct: 209 LVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDN---ASALYEACK 265
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V+ L++ GAD N D PLH A +V+ LL + + +P
Sbjct: 266 NEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRRSGV-SP 324
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKA--------TALHLAAEDGHAECARLLLD 273
LH+AA + LL+A DV + P +A +AL+ A + + LLL
Sbjct: 325 LHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQ 384
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
HGA PN +PL +A L +++L+D A++ A A T I+ +
Sbjct: 385 HGAD---PNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCL 441
Query: 334 DIARLLLSAGAD 345
+ + L+ G D
Sbjct: 442 SLLKFLMDLGCD 453
Score = 52.8 bits (121), Expect = 4e-06
Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 7/147 (4%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL---AQSLEVVEMLVDRCA 309
A L A +DG E + ++ G ++ PN G PLH A L+V++
Sbjct: 58 ADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTI 117
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
D R + T ++ A RG C ++ LL AGA+P+ ++ TPL+ A + + V
Sbjct: 118 DQRTLQEE--TAVYLATCRGHLDCLLS--LLQAGAEPDISNKSRETPLYKACERKNAEAV 173
Query: 370 LLLLDYGGDVTLRTNGGVSALSFIVRR 396
+L+ + D R N G +AL V R
Sbjct: 174 KILVQHNADTNHRCNRGWTALHESVSR 200
>AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein
protein.
Length = 587
Score = 99.5 bits (237), Expect = 4e-20
Identities = 82/276 (29%), Positives = 124/276 (44%), Gaps = 9/276 (3%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI-AHGADVNAG-LSD 185
G EE +K ++ G N + + E PLH AA + C+KVL A+ ++ L +
Sbjct: 68 GDEEALKTMIKEGK--NLAEPNKEGWL-PLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQE 124
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
+ ++ A + + LL+AGA PD ETPL+ A +A K+L+ AD
Sbjct: 125 ETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTN 184
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G TALH + E ++L+ GA ++ N G TPL +A + LE + L
Sbjct: 185 HRCNRGW-TALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLA 243
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
AD+ + +D + L+ A ++ LLS GAD N + G PLHIA+
Sbjct: 244 KYGADINTQASDNASALYEACKNEHE--EVVEFLLSQGADANKTNKDGLLPLHIASKKGN 301
Query: 366 SACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
V +LL +R GVS L R D +
Sbjct: 302 YRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEV 336
Score = 92.7 bits (220), Expect = 4e-18
Identities = 63/208 (30%), Positives = 97/208 (46%), Gaps = 2/208 (0%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
L+ PL A+ E +K +++ G P PLH AA G C K+L A
Sbjct: 55 LAPADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYP 114
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+ TA++LA GH +C LL GA D N +TPL+ A ++ E V+
Sbjct: 115 GTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVK 174
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
+LV AD + G T LH ++ R ++ ++L+S GA + + +G TPL +AA
Sbjct: 175 ILVQHNADTNHRCNRGWTALHESVSR--NDLEVMQILVSGGAKVESKNAYGITPLFVAAQ 232
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ + L YG D+ + + SAL
Sbjct: 233 SGQLEALRFLAKYGADINTQASDNASAL 260
Score = 87.8 bits (208), Expect = 1e-16
Identities = 82/286 (28%), Positives = 126/286 (44%), Gaps = 7/286 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G L ++K G + E + G LH + G C+K+L A+P T D T +
Sbjct: 68 GDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVL--QRAYPGTIDQRTLQEE 125
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
T ++ A L C+ L+ GA+ + R +PL+ A E VK L++ A +
Sbjct: 126 TAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNH 185
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
T LH + S ++L++ GA V + G T L +AA+ G E R L
Sbjct: 186 RCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG-ITPLFVAAQSGQLEALRFLAK 244
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+GA I+ + L+ A + EVVE L+ + AD + DG PLH A +G
Sbjct: 245 YGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYR- 303
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
I ++LL + + G +PLH+AA + LL DV
Sbjct: 304 -IVQMLLPVTSRTRIRRS-GVSPLHLAAERNHDEVLEALLSARFDV 347
Score = 80.2 bits (189), Expect = 2e-14
Identities = 84/302 (27%), Positives = 131/302 (43%), Gaps = 16/302 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G L LL+ G +PD + + T L+ +C + E VK+L+ H A N
Sbjct: 126 TAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTN- 184
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
T LH + S L +++L++ GA V + +PL A S E ++ L
Sbjct: 185 --HRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFL 242
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
+ GA +T + L+ A + LL+ GAD G LH+A++ G+
Sbjct: 243 AKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDG-LLPLHIASKKGN 301
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH- 323
++LL + G +PLHLA EV+E L+ DV A R L+
Sbjct: 302 YRIVQMLLPVTSRTRIRR-SGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYE 360
Query: 324 ----GAIVRGARACDI--ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
A+ ++ LLL GADPN +PL +A + + LLLD+G
Sbjct: 361 DRRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVAIRHGCLRTMQLLLDHGA 417
Query: 378 DV 379
++
Sbjct: 418 NI 419
Score = 78.2 bits (184), Expect = 1e-13
Identities = 71/239 (29%), Positives = 100/239 (41%), Gaps = 5/239 (2%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEA-GACP 211
A PL A +K +I G ++ PLH A +K L A
Sbjct: 58 ADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTI 117
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
D + ET +++A G C LL AGA+ + + T L+ A E +AE ++L
Sbjct: 118 DQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDIS-NKSRETPLYKACERKNAEAVKIL 176
Query: 272 LDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGAR 331
+ H A + RG T LH + LEV+++LV A V +K+A G TPL A G
Sbjct: 177 VQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSG-- 234
Query: 332 ACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ R L GAD N + + L+ A NE V LL G D G+ L
Sbjct: 235 QLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPL 293
Score = 66.1 bits (154), Expect = 4e-10
Identities = 67/252 (26%), Positives = 108/252 (42%), Gaps = 16/252 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+ G + + G T L ++ G E ++ L +GA NT S A+ L+ A
Sbjct: 209 LVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDN---ASALYEACK 265
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V+ L++ GAD N D PLH A +V+ LL + + +P
Sbjct: 266 NEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRRSGV-SP 324
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKA--------TALHLAAEDGHAECARLLLD 273
LH+AA + LL+A DV + P +A +AL+ A + + LLL
Sbjct: 325 LHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQ 384
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
HGA PN +PL +A L +++L+D A++ A A T I+ +
Sbjct: 385 HGAD---PNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCL 441
Query: 334 DIARLLLSAGAD 345
+ + L+ G D
Sbjct: 442 SLLKFLMDLGCD 453
Score = 52.8 bits (121), Expect = 4e-06
Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 7/147 (4%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL---AQSLEVVEMLVDRCA 309
A L A +DG E + ++ G ++ PN G PLH A L+V++
Sbjct: 58 ADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTI 117
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
D R + T ++ A RG C ++ LL AGA+P+ ++ TPL+ A + + V
Sbjct: 118 DQRTLQEE--TAVYLATCRGHLDCLLS--LLQAGAEPDISNKSRETPLYKACERKNAEAV 173
Query: 370 LLLLDYGGDVTLRTNGGVSALSFIVRR 396
+L+ + D R N G +AL V R
Sbjct: 174 KILVQHNADTNHRCNRGWTALHESVSR 200
>AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteining
protein with a SOCS box-2 protein.
Length = 587
Score = 99.5 bits (237), Expect = 4e-20
Identities = 82/276 (29%), Positives = 124/276 (44%), Gaps = 9/276 (3%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI-AHGADVNAG-LSD 185
G EE +K ++ G N + + E PLH AA + C+KVL A+ ++ L +
Sbjct: 68 GDEEALKTMIKEGK--NLAEPNKEGWL-PLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQE 124
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
+ ++ A + + LL+AGA PD ETPL+ A +A K+L+ AD
Sbjct: 125 ETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTN 184
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G TALH + E ++L+ GA ++ N G TPL +A + LE + L
Sbjct: 185 HRCNRGW-TALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLA 243
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
AD+ + +D + L+ A ++ LLS GAD N + G PLHIA+
Sbjct: 244 KYGADINTQASDNASALYEACKNEHE--EVVEFLLSQGADANKTNKDGLLPLHIASKKGN 301
Query: 366 SACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
V +LL +R GVS L R D +
Sbjct: 302 YRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEV 336
Score = 92.7 bits (220), Expect = 4e-18
Identities = 63/208 (30%), Positives = 97/208 (46%), Gaps = 2/208 (0%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
L+ PL A+ E +K +++ G P PLH AA G C K+L A
Sbjct: 55 LAPADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYP 114
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+ TA++LA GH +C LL GA D N +TPL+ A ++ E V+
Sbjct: 115 GTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVK 174
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
+LV AD + G T LH ++ R ++ ++L+S GA + + +G TPL +AA
Sbjct: 175 ILVQHNADTNHRCNRGWTALHESVSR--NDLEVMQILVSGGAKVESKNAYGITPLFVAAQ 232
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ + L YG D+ + + SAL
Sbjct: 233 SGQLEALRFLAKYGADINTQASDNASAL 260
Score = 87.8 bits (208), Expect = 1e-16
Identities = 82/286 (28%), Positives = 126/286 (44%), Gaps = 7/286 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G L ++K G + E + G LH + G C+K+L A+P T D T +
Sbjct: 68 GDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVL--QRAYPGTIDQRTLQEE 125
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
T ++ A L C+ L+ GA+ + R +PL+ A E VK L++ A +
Sbjct: 126 TAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNH 185
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
T LH + S ++L++ GA V + G T L +AA+ G E R L
Sbjct: 186 RCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG-ITPLFVAAQSGQLEALRFLAK 244
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+GA I+ + L+ A + EVVE L+ + AD + DG PLH A +G
Sbjct: 245 YGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYR- 303
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
I ++LL + + G +PLH+AA + LL DV
Sbjct: 304 -IVQMLLPVTSRTRIRRS-GVSPLHLAAERNHDEVLEALLSARFDV 347
Score = 80.2 bits (189), Expect = 2e-14
Identities = 84/302 (27%), Positives = 131/302 (43%), Gaps = 16/302 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G L LL+ G +PD + + T L+ +C + E VK+L+ H A N
Sbjct: 126 TAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTN- 184
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKEL 204
T LH + S L +++L++ GA V + +PL A S E ++ L
Sbjct: 185 --HRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFL 242
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
+ GA +T + L+ A + LL+ GAD G LH+A++ G+
Sbjct: 243 AKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDG-LLPLHIASKKGN 301
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH- 323
++LL + G +PLHLA EV+E L+ DV A R L+
Sbjct: 302 YRIVQMLLPVTSRTRIRR-SGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYE 360
Query: 324 ----GAIVRGARACDI--ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
A+ ++ LLL GADPN +PL +A + + LLLD+G
Sbjct: 361 DRRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVAIRHGCLRTMQLLLDHGA 417
Query: 378 DV 379
++
Sbjct: 418 NI 419
Score = 78.2 bits (184), Expect = 1e-13
Identities = 71/239 (29%), Positives = 100/239 (41%), Gaps = 5/239 (2%)
Query: 154 ATPLHCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEA-GACP 211
A PL A +K +I G ++ PLH A +K L A
Sbjct: 58 ADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTI 117
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
D + ET +++A G C LL AGA+ + + T L+ A E +AE ++L
Sbjct: 118 DQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDIS-NKSRETPLYKACERKNAEAVKIL 176
Query: 272 LDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGAR 331
+ H A + RG T LH + LEV+++LV A V +K+A G TPL A G
Sbjct: 177 VQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSG-- 234
Query: 332 ACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ R L GAD N + + L+ A NE V LL G D G+ L
Sbjct: 235 QLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPL 293
Score = 66.1 bits (154), Expect = 4e-10
Identities = 67/252 (26%), Positives = 108/252 (42%), Gaps = 16/252 (6%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L+ G + + G T L ++ G E ++ L +GA NT S A+ L+ A
Sbjct: 209 LVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDN---ASALYEACK 265
Query: 163 AKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
+ V+ L++ GAD N D PLH A +V+ LL + + +P
Sbjct: 266 NEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRRSGV-SP 324
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKA--------TALHLAAEDGHAECARLLLD 273
LH+AA + LL+A DV + P +A +AL+ A + + LLL
Sbjct: 325 LHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQ 384
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
HGA PN +PL +A L +++L+D A++ A A T I+ +
Sbjct: 385 HGAD---PNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCL 441
Query: 334 DIARLLLSAGAD 345
+ + L+ G D
Sbjct: 442 SLLKFLMDLGCD 453
Score = 52.8 bits (121), Expect = 4e-06
Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 7/147 (4%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL---AQSLEVVEMLVDRCA 309
A L A +DG E + ++ G ++ PN G PLH A L+V++
Sbjct: 58 ADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTI 117
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
D R + T ++ A RG C ++ LL AGA+P+ ++ TPL+ A + + V
Sbjct: 118 DQRTLQEE--TAVYLATCRGHLDCLLS--LLQAGAEPDISNKSRETPLYKACERKNAEAV 173
Query: 370 LLLLDYGGDVTLRTNGGVSALSFIVRR 396
+L+ + D R N G +AL V R
Sbjct: 174 KILVQHNADTNHRCNRGWTALHESVSR 200
>BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein
protein.
Length = 714
Score = 98.7 bits (235), Expect = 7e-20
Identities = 82/269 (30%), Positives = 124/269 (46%), Gaps = 15/269 (5%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A + + L+ LL G D ++ G T LH++ + G E +LL HGA+ N
Sbjct: 221 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 280
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG--LSDRSPLHYAVLSDAPEVVKE 203
D+ TPLH AA ++L+ GADVN + DR PLH A + K
Sbjct: 281 QDA---VFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDR-PLHLASAKGFLNIAKL 336
Query: 204 LLEAGACPDTPQVFTE--TPLHVAASLGSASCTKLLLNAGADVRA-AMGPGKATALHLAA 260
L+E G+ D E PLH + G K LL + +V+ + T LHLA
Sbjct: 337 LMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLLQSDLEVQPHVVNIYGDTPLHLAC 396
Query: 261 EDGHAECARLLLDHGA--HIDWPNFRGQTPLHLA-TLAQSLEVVEMLVDR-CADVRAKDA 316
+G E A+ ++ + N +T H A T +S+++V+ L+D+ ++ +
Sbjct: 397 YNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQNVININHQGR 456
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGAD 345
DG T LH A G + + LL GAD
Sbjct: 457 DGHTGLHSACYHG--HIRLVQFLLDNGAD 483
Score = 97.5 bits (232), Expect = 2e-19
Identities = 88/297 (29%), Positives = 127/297 (42%), Gaps = 17/297 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK + L+ G+ P L G T LHL+ + E + LL GA
Sbjct: 197 GKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSLLHSGADIQQVGYG---GL 253
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVKELLEAGACP 211
T LH A A L VL+ HGA+VN + D +PLH A +V + LL+ GA
Sbjct: 254 TALHIATIAGHLEAADVLLQHGANVN--IQDAVFFTPLHIAAYYGHEQVTRLLLKFGADV 311
Query: 212 DTPQVFTETPLHVAASLGSASCTKLLLNAG--ADVRAAMGPGKATALHLAAEDGHAECAR 269
+ + PLH+A++ G + KLL+ G ADV A LH + GH + +
Sbjct: 312 NVSGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDH-VPLHFCSRFGHHDMVK 370
Query: 270 LLLDHGAHID--WPNFRGQTPLHLATLAQSLEVVEML--VDRCADVRAKDADGRTPLHGA 325
LL + N G TPLHLA EV + + + + ++ T H A
Sbjct: 371 YLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSA 430
Query: 326 IVRGARACDIARLLLSAGA-DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTL 381
G ++ D+ + LL + N G+T LH A + V LLD G D++L
Sbjct: 431 CTYG-KSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMSL 486
Score = 87.0 bits (206), Expect = 2e-16
Identities = 73/252 (28%), Positives = 116/252 (46%), Gaps = 14/252 (5%)
Query: 117 GRTCLHLSCLVGSEEC-VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL C+ G ++ ++ L+ G P+ T T LH A + + L+
Sbjct: 185 GLSLLHLCCICGGKKSHIRTLMLKGLRPSRL---TRNGFTALHLAVYKDNAELITSLLHS 241
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GAD+ G + LH A ++ E LL+ GA + TPLH+AA G T
Sbjct: 242 GADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVT 301
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG--AHIDWPNFRGQTPLHLA 292
+LLL GADV + G LHLA+ G A+LL++ G A ++ + PLH
Sbjct: 302 RLLLKFGADVNVS-GEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFC 360
Query: 293 TLAQSLEVVEMLVDRCADVRAKDAD--GRTPLHGAIVRGARACDIARLLLS-AGADPNAA 349
+ ++V+ L+ +V+ + G TPLH A G ++A+ ++ +G +
Sbjct: 361 SRFGHHDMVKYLLQSDLEVQPHVVNIYGDTPLHLACYNG--KFEVAKEIIQISGTESLTK 418
Query: 350 DN-FGYTPLHIA 360
+N F T H A
Sbjct: 419 ENIFSETAFHSA 430
Score = 84.6 bits (200), Expect = 1e-15
Identities = 59/158 (37%), Positives = 78/158 (49%), Gaps = 4/158 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALHLA +AE LL GA I + G T LH+AT+A LE ++L+ A+V
Sbjct: 221 TALHLAVYKDNAELITSLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNI 280
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+DA TPLH A G + RLLL GAD N + G PLH+A+ F LL+
Sbjct: 281 QDAVFFTPLHIAAYYGHE--QVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLLM 338
Query: 374 DYG--GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFD 409
+ G DV + N L F R + +YL + D
Sbjct: 339 EEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLLQSD 376
Score = 79.0 bits (186), Expect = 6e-14
Identities = 72/239 (30%), Positives = 108/239 (45%), Gaps = 11/239 (4%)
Query: 81 GFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
G+G TA+ A G LL+ G + + D T LH++ G E+ +LLL G
Sbjct: 249 GYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFG 308
Query: 141 AHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHG--ADVNA-GLSDRSPLHYAVLSDA 197
A N S E PLH A++ L K+L+ G ADVNA D PLH+
Sbjct: 309 ADVNV---SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGH 365
Query: 198 PEVVKELLEAG--ACPDTPQVFTETPLHVAASLGSASCTKLLLN-AGADVRAAMGPGKAT 254
++VK LL++ P ++ +TPLH+A G K ++ +G + T
Sbjct: 366 HDMVKYLLQSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSET 425
Query: 255 ALHLAAEDGHA-ECARLLLDHGA-HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV 311
A H A G + + + LLD +I+ G T LH A + +V+ L+D AD+
Sbjct: 426 AFHSACTYGKSIDLVKFLLDQNVININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADM 484
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 1/74 (1%)
Query: 317 DGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+G + LH + G + I L+L G P+ G+T LH+A + + + LL G
Sbjct: 184 NGLSLLHLCCICGGKKSHIRTLMLK-GLRPSRLTRNGFTALHLAVYKDNAELITSLLHSG 242
Query: 377 GDVTLRTNGGVSAL 390
D+ GG++AL
Sbjct: 243 ADIQQVGYGGLTAL 256
>BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 16
protein.
Length = 361
Score = 98.7 bits (235), Expect = 7e-20
Identities = 92/292 (31%), Positives = 127/292 (43%), Gaps = 22/292 (7%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
+ +L + G+D + + + LH + +G +CV+ LL GA D + T
Sbjct: 50 RDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGA---AVDCLKKADWT 106
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPD-- 212
PL A + K+L ++ L+ HGA+ D + H A P +++ LL CP
Sbjct: 107 PLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTV--CPGAW 164
Query: 213 -TPQVFTETPLHVAASLGSASCTKLLLNA---GADVRAAMGPGKATALHLAAEDGHAECA 268
T TPLH AA G K+LL D R G TAL A + GH + A
Sbjct: 165 KTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCG---VTALMDAIQCGHIDVA 221
Query: 269 RLLLD-HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA---DVRAKDADGRTPLHG 324
RLLLD HGA + + G LH A + E + LV DVRA T LH
Sbjct: 222 RLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTH-LTALHY 280
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
A G + + LLS GAD N+ D + LH+A + AC LL G
Sbjct: 281 AAKEGHTST--IQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSG 330
Score = 79.4 bits (187), Expect = 4e-14
Identities = 80/279 (28%), Positives = 119/279 (42%), Gaps = 7/279 (2%)
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
AG T LH + G + + L + A +++ PLH AAS CV+ L+
Sbjct: 36 AGDTLLHCAARHGHRDVLAYLAE--AWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGR 93
Query: 176 GADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GA V+ +D +PL A V++EL+E GA P H+A+ G
Sbjct: 94 GAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLIL 153
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI-DWPNFRGQTPLHLAT 293
+ LL + T LH AA GH E ++LL + D+ + G T L A
Sbjct: 154 QYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAI 213
Query: 294 LAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNA-ADN 351
++V +L+D A + A+D+ G LH A V G I L+ G D + A +
Sbjct: 214 QCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEA-IRFLVSELGVDVDVRATS 272
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
T LH AA ++ + LL G D+ + SAL
Sbjct: 273 THLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSAL 311
Score = 74.5 bits (175), Expect = 1e-12
Identities = 63/225 (28%), Positives = 98/225 (43%), Gaps = 8/225 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ AC ++ +L++ G +P + G H++ G ++ LL P
Sbjct: 106 TPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLT--VCPGA 163
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVK 202
W + ++ + TPLH AA L VKVL+ D + L A+ +V +
Sbjct: 164 WKTESKIRRTPLHTAAMHGHLEAVKVLLKR-CQYEPDYRDNCGVTALMDAIQCGHIDVAR 222
Query: 203 ELL-EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAA 260
LL E GAC LH AA G + L++ G DV TALH AA
Sbjct: 223 LLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAA 282
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
++GH + LL GA I+ + + ++ LHLA Q L + L+
Sbjct: 283 KEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLL 327
Score = 69.7 bits (163), Expect = 3e-11
Identities = 70/221 (31%), Positives = 93/221 (42%), Gaps = 7/221 (3%)
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAA 260
+EL AG CP +T LH AA G L A G D+ A K LH AA
Sbjct: 24 EELQAAGGCPGPAG---DTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRP-LHEAA 79
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
GH +C R LL GA +D TPL +A ++L V++ LV+ A+ K+ DG
Sbjct: 80 SMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWN 139
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN-EFSACVLLLLDYGGDV 379
H A G L + GA TPLH AA++ A +LL +
Sbjct: 140 SFHIASREGDPLILQYLLTVCPGA-WKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEP 198
Query: 380 TLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHELG 420
R N GV+AL ++ + R L A +E LG
Sbjct: 199 DYRDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLG 239
Score = 37.1 bits (82), Expect = 0.23
Identities = 19/55 (34%), Positives = 28/55 (50%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
TA+ +A G + + LL +G D + D+ R+ LHL+C C K LL G
Sbjct: 276 TALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSG 330
>BC016881-1|AAH16881.1| 638|Homo sapiens Unknown (protein for
IMAGE:3914496) protein.
Length = 638
Score = 98.7 bits (235), Expect = 7e-20
Identities = 68/207 (32%), Positives = 97/207 (46%), Gaps = 5/207 (2%)
Query: 175 HGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
H AD N DR + A D +V L + G P V + HV S G+ C
Sbjct: 14 HAADWNK-YDDRL-MKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECL 71
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL 294
+L G D+ + G+ ALHLAA+ GHA C + LL + + + +G+T LH A +
Sbjct: 72 NAILIHGVDITTSDTAGR-NALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAM 130
Query: 295 AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGY 354
A +++L D A V AKD DGRTPL + I +LL+ GAD N+ D
Sbjct: 131 ADCPSSIQLLCDHGASVNAKDVDGRTPL--VLATQMSRPTICQLLIDRGADVNSRDKQNR 188
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTL 381
T L + V +L+ G D++L
Sbjct: 189 TALMLGCEYGCRDAVEVLIKNGADISL 215
Score = 93.5 bits (222), Expect = 2e-18
Identities = 60/203 (29%), Positives = 101/203 (49%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K GV+P +LD GR+ H+ G+ EC+ +L HG T D++ LH AA
Sbjct: 41 LAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNA---LHLAAK 97
Query: 163 AKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
C++ L+ + +A L R+ LH A ++D P ++ L + GA + V TP
Sbjct: 98 YGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTP 157
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L +A + + +LL++ GADV + + TAL L E G + +L+ +GA I
Sbjct: 158 LVLATQMSRPTICQLLIDRGADVNSRDKQNR-TALMLGCEYGCRDAVEVLIKNGADISLL 216
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G + A + +L+++ +L
Sbjct: 217 DALGHDSSYYARIGDNLDILTLL 239
Score = 68.5 bits (160), Expect = 8e-11
Identities = 60/219 (27%), Positives = 96/219 (43%), Gaps = 7/219 (3%)
Query: 130 EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSDRSP 188
E+ +L G +P D E ++ H S +L C+ ++ HG D+ + R+
Sbjct: 35 EKVTSILAKKGVNPGKLD--VEGRSV-FHVVTSKGNLECLNAILIHGVDITTSDTAGRNA 91
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH A +++LL+ + + T LH AA S +LL + GA V A
Sbjct: 92 LHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKD 151
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G+ T L LA + +LL+D GA ++ + + +T L L + VE+L+
Sbjct: 152 VDGR-TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNG 210
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
AD+ DA G + A R DI LL +A + N
Sbjct: 211 ADISLLDALGHDSSYYA--RIGDNLDILTLLKTASENTN 247
Score = 61.7 bits (143), Expect = 9e-09
Identities = 46/138 (33%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT-LAQSLEVVEMLVDRCADVR 312
+ H+ G+ EC +L HG I + G+ LHLA +L + ++L C
Sbjct: 57 SVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 116
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D GRT LH A + A +LL GA NA D G TPL +A LL
Sbjct: 117 A-DLQGRTALHDAAM--ADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLL 173
Query: 373 LDYGGDVTLRTNGGVSAL 390
+D G DV R +AL
Sbjct: 174 IDRGADVNSRDKQNRTAL 191
Score = 52.0 bits (119), Expect = 7e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R A+ A G ++ L KLL+ + D GRT LH + + ++LL DHGA N
Sbjct: 89 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVN 148
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D TPL A ++LI GADVN+ +R+ L + V+
Sbjct: 149 AKDVDGR---TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEV 205
Query: 204 LLEAGA 209
L++ GA
Sbjct: 206 LIKNGA 211
Score = 35.1 bits (77), Expect = 0.92
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT ++ A + + + L+ G D + D RT L L C G + V++L+ +GA +
Sbjct: 155 RTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADIS 214
Query: 145 TWDS 148
D+
Sbjct: 215 LLDA 218
>AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 16
protein.
Length = 361
Score = 98.7 bits (235), Expect = 7e-20
Identities = 92/292 (31%), Positives = 127/292 (43%), Gaps = 22/292 (7%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
+ +L + G+D + + + LH + +G +CV+ LL GA D + T
Sbjct: 50 RDVLAYLAEAWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGRGA---AVDCLKKADWT 106
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPD-- 212
PL A + K+L ++ L+ HGA+ D + H A P +++ LL CP
Sbjct: 107 PLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLTV--CPGAW 164
Query: 213 -TPQVFTETPLHVAASLGSASCTKLLLNA---GADVRAAMGPGKATALHLAAEDGHAECA 268
T TPLH AA G K+LL D R G TAL A + GH + A
Sbjct: 165 KTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCG---VTALMDAIQCGHIDVA 221
Query: 269 RLLLD-HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA---DVRAKDADGRTPLHG 324
RLLLD HGA + + G LH A + E + LV DVRA T LH
Sbjct: 222 RLLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTH-LTALHY 280
Query: 325 AIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
A G + + LLS GAD N+ D + LH+A + AC LL G
Sbjct: 281 AAKEGHTST--IQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSG 330
Score = 79.4 bits (187), Expect = 4e-14
Identities = 80/279 (28%), Positives = 119/279 (42%), Gaps = 7/279 (2%)
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
AG T LH + G + + L + A +++ PLH AAS CV+ L+
Sbjct: 36 AGDTLLHCAARHGHRDVLAYLAE--AWGMDIEATNRDYKRPLHEAASMGHRDCVRYLLGR 93
Query: 176 GADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
GA V+ +D +PL A V++EL+E GA P H+A+ G
Sbjct: 94 GAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLIL 153
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI-DWPNFRGQTPLHLAT 293
+ LL + T LH AA GH E ++LL + D+ + G T L A
Sbjct: 154 QYLLTVCPGAWKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEPDYRDNCGVTALMDAI 213
Query: 294 LAQSLEVVEMLVDRC-ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNA-ADN 351
++V +L+D A + A+D+ G LH A V G I L+ G D + A +
Sbjct: 214 QCGHIDVARLLLDEHGACLSAEDSLGAQALHRAAVTGQDEA-IRFLVSELGVDVDVRATS 272
Query: 352 FGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
T LH AA ++ + LL G D+ + SAL
Sbjct: 273 THLTALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSAL 311
Score = 74.5 bits (175), Expect = 1e-12
Identities = 63/225 (28%), Positives = 98/225 (43%), Gaps = 8/225 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ AC ++ +L++ G +P + G H++ G ++ LL P
Sbjct: 106 TPLMMACTRKNLGVIQELVEHGANPLLKNKDGWNSFHIASREGDPLILQYLLT--VCPGA 163
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLSDAPEVVK 202
W + ++ + TPLH AA L VKVL+ D + L A+ +V +
Sbjct: 164 WKTESKIRRTPLHTAAMHGHLEAVKVLLKR-CQYEPDYRDNCGVTALMDAIQCGHIDVAR 222
Query: 203 ELL-EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAA 260
LL E GAC LH AA G + L++ G DV TALH AA
Sbjct: 223 LLLDEHGACLSAEDSLGAQALHRAAVTGQDEAIRFLVSELGVDVDVRATSTHLTALHYAA 282
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
++GH + LL GA I+ + + ++ LHLA Q L + L+
Sbjct: 283 KEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLL 327
Score = 69.7 bits (163), Expect = 3e-11
Identities = 70/221 (31%), Positives = 93/221 (42%), Gaps = 7/221 (3%)
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA-GADVRAAMGPGKATALHLAA 260
+EL AG CP +T LH AA G L A G D+ A K LH AA
Sbjct: 24 EELQAAGGCPGPAG---DTLLHCAARHGHRDVLAYLAEAWGMDIEATNRDYKRP-LHEAA 79
Query: 261 EDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
GH +C R LL GA +D TPL +A ++L V++ LV+ A+ K+ DG
Sbjct: 80 SMGHRDCVRYLLGRGAAVDCLKKADWTPLMMACTRKNLGVIQELVEHGANPLLKNKDGWN 139
Query: 321 PLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALN-EFSACVLLLLDYGGDV 379
H A G L + GA TPLH AA++ A +LL +
Sbjct: 140 SFHIASREGDPLILQYLLTVCPGA-WKTESKIRRTPLHTAAMHGHLEAVKVLLKRCQYEP 198
Query: 380 TLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHELG 420
R N GV+AL ++ + R L A +E LG
Sbjct: 199 DYRDNCGVTALMDAIQCGHIDVARLLLDEHGACLSAEDSLG 239
Score = 37.1 bits (82), Expect = 0.23
Identities = 19/55 (34%), Positives = 28/55 (50%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHG 140
TA+ +A G + + LL +G D + D+ R+ LHL+C C K LL G
Sbjct: 276 TALHYAAKEGHTSTIQTLLSLGADINSKDEKNRSALHLACAGQHLACAKFLLQSG 330
>AK055435-1|BAB70922.1| 634|Homo sapiens protein ( Homo sapiens
cDNA FLJ30873 fis, clone FEBRA2004325, moderately
similar to Canis familiaris mRNA for C3VS protein. ).
Length = 634
Score = 98.7 bits (235), Expect = 7e-20
Identities = 68/207 (32%), Positives = 97/207 (46%), Gaps = 5/207 (2%)
Query: 175 HGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
H AD N DR + A D +V L + G P V + HV S G+ C
Sbjct: 14 HAADWNK-YDDRL-MKAAERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECL 71
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL 294
+L G D+ + G+ ALHLAA+ GHA C + LL + + + +G+T LH A +
Sbjct: 72 NAILIHGVDITTSDTAGR-NALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAM 130
Query: 295 AQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGY 354
A +++L D A V AKD DGRTPL + I +LL+ GAD N+ D
Sbjct: 131 ADCPSSIQLLCDHGASVNAKDVDGRTPL--VLATQMSRPTICQLLIDRGADVNSRDKQNR 188
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTL 381
T L + V +L+ G D++L
Sbjct: 189 TALMLGCEYGCRDAVEVLIKNGADISL 215
Score = 93.5 bits (222), Expect = 2e-18
Identities = 60/203 (29%), Positives = 101/203 (49%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L K GV+P +LD GR+ H+ G+ EC+ +L HG T D++ LH AA
Sbjct: 41 LAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNA---LHLAAK 97
Query: 163 AKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
C++ L+ + +A L R+ LH A ++D P ++ L + GA + V TP
Sbjct: 98 YGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKDVDGRTP 157
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L +A + + +LL++ GADV + + TAL L E G + +L+ +GA I
Sbjct: 158 LVLATQMSRPTICQLLIDRGADVNSRDKQNR-TALMLGCEYGCRDAVEVLIKNGADISLL 216
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ G + A + +L+++ +L
Sbjct: 217 DALGHDSSYYARIGDNLDILTLL 239
Score = 68.5 bits (160), Expect = 8e-11
Identities = 60/219 (27%), Positives = 96/219 (43%), Gaps = 7/219 (3%)
Query: 130 EECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAG-LSDRSP 188
E+ +L G +P D E ++ H S +L C+ ++ HG D+ + R+
Sbjct: 35 EKVTSILAKKGVNPGKLD--VEGRSV-FHVVTSKGNLECLNAILIHGVDITTSDTAGRNA 91
Query: 189 LHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAM 248
LH A +++LL+ + + T LH AA S +LL + GA V A
Sbjct: 92 LHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVNAKD 151
Query: 249 GPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRC 308
G+ T L LA + +LL+D GA ++ + + +T L L + VE+L+
Sbjct: 152 VDGR-TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNG 210
Query: 309 ADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
AD+ DA G + A R DI LL +A + N
Sbjct: 211 ADISLLDALGHDSSYYA--RIGDNLDILTLLKTASENTN 247
Score = 61.7 bits (143), Expect = 9e-09
Identities = 46/138 (33%), Positives = 61/138 (44%), Gaps = 4/138 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLAT-LAQSLEVVEMLVDRCADVR 312
+ H+ G+ EC +L HG I + G+ LHLA +L + ++L C
Sbjct: 57 SVFHVVTSKGNLECLNAILIHGVDITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEH 116
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D GRT LH A + A +LL GA NA D G TPL +A LL
Sbjct: 117 A-DLQGRTALHDAAM--ADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLL 173
Query: 373 LDYGGDVTLRTNGGVSAL 390
+D G DV R +AL
Sbjct: 174 IDRGADVNSRDKQNRTAL 191
Score = 52.0 bits (119), Expect = 7e-06
Identities = 39/126 (30%), Positives = 57/126 (45%), Gaps = 4/126 (3%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
R A+ A G ++ L KLL+ + D GRT LH + + ++LL DHGA N
Sbjct: 89 RNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTALHDAAMADCPSSIQLLCDHGASVN 148
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
D TPL A ++LI GADVN+ +R+ L + V+
Sbjct: 149 AKDVDGR---TPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEV 205
Query: 204 LLEAGA 209
L++ GA
Sbjct: 206 LIKNGA 211
Score = 35.1 bits (77), Expect = 0.92
Identities = 18/64 (28%), Positives = 32/64 (50%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT ++ A + + + L+ G D + D RT L L C G + V++L+ +GA +
Sbjct: 155 RTPLVLATQMSRPTICQLLIDRGADVNSRDKQNRTALMLGCEYGCRDAVEVLIKNGADIS 214
Query: 145 TWDS 148
D+
Sbjct: 215 LLDA 218
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 98.3 bits (234), Expect = 9e-20
Identities = 101/395 (25%), Positives = 172/395 (43%), Gaps = 12/395 (3%)
Query: 19 SDESAHGADLAERLRVK-PSKDIWELDEIQYT-LRLLPYSEEISVLIGNGNYDETIQFAS 76
S+ SA D RL VK P K + D +Q+ ++ + +S N ++ +FA+
Sbjct: 242 SNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAA 301
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ +R L L +S L + + D LD+ + +++ V L
Sbjct: 302 RKKWKQSVRLISLCQR-LSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL 360
Query: 137 LDHGAHPNTWDSSTETK--ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAV 193
+ +D + K PL AA ++ +++LI G+ ++ + +++A
Sbjct: 361 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA 420
Query: 194 LSDAPEVVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ +K L E CP D E LHVAA G A ++ A A + + +
Sbjct: 421 RHGHVDTLKFLSE-NKCPLDVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEE 479
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
T LH AA G+ A+ L + G +++ N G+TPL A+ ++VE L + AD+
Sbjct: 480 ETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 539
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D DG LH A+ R ++ + LLS G + D G TPLH+A + V+ L
Sbjct: 540 ACDKDGHIALHLAVRR--CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 597
Query: 373 LDYGGDVTLRTNGGVSALSFIVRR-VPDVIPRYLC 406
+ ++ + G + L + DV+ RYLC
Sbjct: 598 CEANCNLDISNKYGRTPLHLAANNGILDVV-RYLC 631
Score = 82.6 bits (195), Expect = 5e-15
Identities = 78/283 (27%), Positives = 124/283 (43%), Gaps = 8/283 (2%)
Query: 109 DPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLAC 168
D ++ + G L ++ G+ + ++LL+ G+ + D + ++ AA +
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGG---SNAVYWAARHGHVDT 427
Query: 169 VKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGA-CPDTPQVFTETPLHVAA 226
+K L + ++ S LH A +V + A A P + ETPLH AA
Sbjct: 428 LKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEEETPLHCAA 487
Query: 227 SLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ 286
G S K L AG +V G+ T L A+ G+ + L +HGA ++ + G
Sbjct: 488 WHGYYSVAKALCEAGCNVNIKNREGE-TPLLTASARGYHDIVECLAEHGADLNACDKDGH 546
Query: 287 TPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADP 346
LHLA +EV++ L+ + V +D G TPLH A G +A L A +
Sbjct: 547 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA--LCEANCNL 604
Query: 347 NAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
+ ++ +G TPLH+AA N V L G V T G +A
Sbjct: 605 DISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTA 647
Score = 77.8 bits (183), Expect = 1e-13
Identities = 71/239 (29%), Positives = 99/239 (41%), Gaps = 4/239 (1%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G A+ WA G L L + D D +G LH++ G + ++ A
Sbjct: 411 GGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVTCAASAQ 470
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVV 201
S T+ + TPLHCAA + K L G +VN +PL A ++V
Sbjct: 471 IPI--SRTKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 528
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L E GA + LH+A K LL+ G V G T LH+A +
Sbjct: 529 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGN-TPLHVACK 587
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
DG+ L + ++D N G+TPLHLA L+VV L A V A DG+T
Sbjct: 588 DGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 646
Score = 68.5 bits (160), Expect = 8e-11
Identities = 61/187 (32%), Positives = 81/187 (43%), Gaps = 5/187 (2%)
Query: 119 TCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD 178
T LH + G K L + G + N + ET PL A++ V+ L HGAD
Sbjct: 481 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGET---PLLTASARGYHDIVECLAEHGAD 537
Query: 179 VNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+NA D LH AV EV+K LL G D TPLHVA G+ L
Sbjct: 538 LNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 597
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
A ++ + G+ T LHLAA +G + R L GA ++ G+T LA Q
Sbjct: 598 CEANCNLDISNKYGR-TPLHLAANNGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQH 656
Query: 298 LEVVEML 304
V +L
Sbjct: 657 EHVAGLL 663
Score = 40.3 bits (90), Expect = 0.024
Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 3/103 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
LL G D D G T LH++C G+ V L + A+ N D S + TPLH AA+
Sbjct: 564 LLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE--ANCNL-DISNKYGRTPLHLAAN 620
Query: 163 AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
L V+ L GA V A +D S+ E V LL
Sbjct: 621 NGILDVVRYLCLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 663
>AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protein 1
protein.
Length = 1431
Score = 98.3 bits (234), Expect = 9e-20
Identities = 80/215 (37%), Positives = 107/215 (49%), Gaps = 12/215 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
S LH+A L+ E++ LLEA A D PLH AA G KL+L AG+ V
Sbjct: 51 SALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSAVNI 110
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV- 305
G LHLAA+ GH + + +LL H ++ + G+TPL LA + VV++L+
Sbjct: 111 PSDEGH-IPLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLS 169
Query: 306 -DRCADV------RAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
+ CA + A D +G +PLH A G DI RLLL AG D N G T LH
Sbjct: 170 SNMCAALLEPRPGDATDPNGTSPLHLAAKNG--HIDIIRLLLQAGIDINRQTKSG-TALH 226
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFI 393
AAL + V LLLD G + +R +AL +
Sbjct: 227 EAALCGKTEVVRLLLDSGINAHVRNTYSQTALDIV 261
Score = 77.4 bits (182), Expect = 2e-13
Identities = 71/236 (30%), Positives = 108/236 (45%), Gaps = 14/236 (5%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
GK+ LL K+ V+ + D G + LH + L G+ E + LLL+ A + D+
Sbjct: 29 GKAKLLGSTKKINVNFQDPD--GFSALHHAALNGNTELISLLLEAQAAVDIKDNK---GM 83
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDT 213
PLH AA +K+++ G+ VN + PLH A +V + LL+ + P
Sbjct: 84 RPLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQSNPCM 143
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRA-------AMGPGKATALHLAAEDGHAE 266
+TPL +A G +LLL++ A P + LHLAA++GH +
Sbjct: 144 VDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHID 203
Query: 267 CARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
RLLL G I+ G T LH A L EVV +L+D + ++ +T L
Sbjct: 204 IIRLLLQAGIDINRQTKSG-TALHEAALCGKTEVVRLLLDSGINAHVRNTYSQTAL 258
Score = 60.9 bits (141), Expect = 2e-08
Identities = 72/246 (29%), Positives = 111/246 (45%), Gaps = 34/246 (13%)
Query: 73 QFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEEC 132
Q A + + G+R + +A W G+ + +LK G + D G LHL+ G +
Sbjct: 72 QAAVDIKDNKGMRP-LHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDV 130
Query: 133 VKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYA 192
++LL H ++P D+S + TPL A + V++L++ +++ A L + P
Sbjct: 131 SEMLLQHQSNPCMVDNSGK---TPLDLACEFGRVGVVQLLLS--SNMCAALLEPRP---- 181
Query: 193 VLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
DA + G P LH+AA G +LLL AG D+ G
Sbjct: 182 --GDATD------PNGTSP----------LHLAAKNGHIDIIRLLLQAGIDINRQTKSG- 222
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPL---HLATLAQ-SLEVVEMLVDRC 308
TALH AA G E RLLLD G + N QT L H T +Q S E+ ++L +
Sbjct: 223 -TALHEAALCGKTEVVRLLLDSGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREAS 281
Query: 309 ADVRAK 314
A ++ +
Sbjct: 282 AALQVR 287
Score = 59.7 bits (138), Expect = 4e-08
Identities = 37/111 (33%), Positives = 57/111 (51%), Gaps = 2/111 (1%)
Query: 250 PGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCA 309
P +ALH AA +G+ E LLL+ A +D + +G PLH A E +++++ +
Sbjct: 47 PDGFSALHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGS 106
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIA 360
V +G PLH A G D++ +LL ++P DN G TPL +A
Sbjct: 107 AVNIPSDEGHIPLHLAAQHG--HYDVSEMLLQHQSNPCMVDNSGKTPLDLA 155
>AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein.
Length = 371
Score = 97.5 bits (232), Expect = 2e-19
Identities = 79/235 (33%), Positives = 111/235 (47%), Gaps = 10/235 (4%)
Query: 163 AKSLACVKVL--IAHGADV-NAGLSDRSP-LHYAVLSDAPEVVKELLEAGACP-DTPQVF 217
+KSL ++++ + HG N G S LH AV + +++ +L+ G D P F
Sbjct: 110 SKSLVKIRMVTSVLHGPPTENTGEPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKF 169
Query: 218 TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAH 277
T L VAA G K+L++ G DV G GK +L LA GH + + L HGA
Sbjct: 170 GFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGK-DSLMLACYAGHLDVVKYLRRHGAS 228
Query: 278 IDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDA-DGRTPL-HGAIVRGARACDI 335
+ G T LH A V+E ++ +V D G TPL + V G + +
Sbjct: 229 WQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQR--V 286
Query: 336 ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
A LL+ AGA+ N D G TPL +A LN V LLLD G D +++ G L
Sbjct: 287 ASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVL 341
Score = 76.2 bits (179), Expect = 4e-13
Identities = 63/209 (30%), Positives = 98/209 (46%), Gaps = 4/209 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
LH + V E+ + +L G D + T L AA VK+L+++G DVN
Sbjct: 140 LHRAVSVNDEDLLVRILQGGRVKV--DVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVN 197
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
S + L A + +VVK L GA + T LH AA G S + ++
Sbjct: 198 LKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIK 257
Query: 240 AGADVRAA-MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSL 298
G +V G G + ++A G+ A LL+D GA+++ + G+TPL +A L
Sbjct: 258 DGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHE 317
Query: 299 EVVEMLVDRCADVRAKDADGRTPLHGAIV 327
E+V++L+D+ AD K+ G+ L A V
Sbjct: 318 ELVQLLLDKGADASVKNEFGKGVLEMARV 346
Score = 70.5 bits (165), Expect = 2e-11
Identities = 66/239 (27%), Positives = 106/239 (44%), Gaps = 11/239 (4%)
Query: 139 HGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR---SPLHYAVLS 195
HG P T ++ + LH A S + V I G V + ++ + L A
Sbjct: 124 HG--PPTENTGEPISSEHLHRAVSVNDEDLL-VRILQGGRVKVDVPNKFGFTALMVAAQK 180
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
+VK L+ G + + L +A G K L GA +A G TA
Sbjct: 181 GYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQAR-DLGGCTA 239
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNF-RGQTPL-HLATLAQSLEVVEMLVDRCADVRA 313
LH AA+ GH ++ G +D + G TPL ++ ++ + V +L+D A+V
Sbjct: 240 LHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNV 299
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
KD +G+TPL A++ ++ +LLL GAD + + FG L +A + + + V LL
Sbjct: 300 KDRNGKTPLMVAVLNNHE--ELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLL 356
Score = 68.5 bits (160), Expect = 8e-11
Identities = 69/220 (31%), Positives = 101/220 (45%), Gaps = 8/220 (3%)
Query: 99 LLFKLLKMG-VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPL 157
LL ++L+ G V D + G T L ++ G VK+L+ +G N + S + L
Sbjct: 151 LLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDS---L 207
Query: 158 HCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQV 216
A A L VK L HGA A L + LH+A V++ +++ G D
Sbjct: 208 MLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDT 267
Query: 217 FTE-TPL-HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH 274
+ TPL V+A G+ LL++AGA+V GK T L +A + H E +LLLD
Sbjct: 268 GSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGK-TPLMVAVLNNHEELVQLLLDK 326
Query: 275 GAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
GA N G+ L +A + VV +L +R R K
Sbjct: 327 GADASVKNEFGKGVLEMARVFDRQSVVSLLEERKKKQRPK 366
Score = 58.4 bits (135), Expect = 9e-08
Identities = 51/175 (29%), Positives = 80/175 (45%), Gaps = 9/175 (5%)
Query: 82 FGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
FG TA++ A G + L+ L+ G D + + +G+ L L+C G + VK L HGA
Sbjct: 169 FGF-TALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGA 227
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD---VNAGLSDRSPLHYAVLSDAP 198
+W + T LH AA + ++ +I G + V+ G + + +S
Sbjct: 228 ---SWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQ 284
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD--VRAAMGPG 251
V L++AGA + +TPL VA +LLL+ GAD V+ G G
Sbjct: 285 RVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKG 339
>BC012056-1|AAH12056.1| 173|Homo sapiens ASB13 protein protein.
Length = 173
Score = 97.1 bits (231), Expect = 2e-19
Identities = 61/158 (38%), Positives = 89/158 (56%), Gaps = 4/158 (2%)
Query: 185 DRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV 244
+R+P+H A +++L+E+GAC + V + TPLH A+ G A C +LLL AGA V
Sbjct: 19 ERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV 78
Query: 245 RAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEML 304
A G +T L A G EC +LLL +GA ++ P + +PLH A ++ S E V +L
Sbjct: 79 DARNIDG-STPLCDACASGSIECVKLLLSYGAKVNPPLYTA-SPLHEACMSGSSECVRLL 136
Query: 305 VDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSA 342
+D A++ A D TPLH A R D ++LL+A
Sbjct: 137 IDVGANLEAHDCHFGTPLHVACAR--EHLDCVKVLLNA 172
Score = 93.5 bits (222), Expect = 2e-18
Identities = 58/156 (37%), Positives = 86/156 (55%), Gaps = 3/156 (1%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RT + A G+S+ L +L++ G +++ T LH + L G CV+LLL GA
Sbjct: 20 RTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV- 78
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKEL 204
D+ +TPL A ++ S+ CVK+L+++GA VN L SPLH A +S + E V+ L
Sbjct: 79 --DARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLL 136
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA 240
++ GA + TPLHVA + C K+LLNA
Sbjct: 137 IDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNA 172
Score = 86.2 bits (204), Expect = 4e-16
Identities = 60/156 (38%), Positives = 82/156 (52%), Gaps = 6/156 (3%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
TP+H AA G + + L+ +GA V T LH A+ G A C +LLL GA +D
Sbjct: 21 TPVHEAAQRGESLQLQQLIESGACVNQVT-VDSITPLHAASLQGQARCVQLLLAAGAQVD 79
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
N G TPL A + S+E V++L+ A V +PLH A + G+ C RLL
Sbjct: 80 ARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTA-SPLHEACMSGSSEC--VRLL 136
Query: 340 LSAGADPNAAD-NFGYTPLHIAALNEFSACVLLLLD 374
+ GA+ A D +FG TPLH+A E CV +LL+
Sbjct: 137 IDVGANLEAHDCHFG-TPLHVACAREHLDCVKVLLN 171
Score = 70.1 bits (164), Expect = 3e-11
Identities = 45/126 (35%), Positives = 68/126 (53%), Gaps = 3/126 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
T +H AA+ G + + L++ GA ++ TPLH A+L V++L+ A V A
Sbjct: 21 TPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDA 80
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
++ DG TPL A G+ C +LLLS GA N + +PLH A ++ S CV LL+
Sbjct: 81 RNIDGSTPLCDACASGSIEC--VKLLLSYGAKVN-PPLYTASPLHEACMSGSSECVRLLI 137
Query: 374 DYGGDV 379
D G ++
Sbjct: 138 DVGANL 143
Score = 54.8 bits (126), Expect = 1e-06
Identities = 37/95 (38%), Positives = 52/95 (54%), Gaps = 4/95 (4%)
Query: 286 QTPLH-LATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGA 344
+TP+H A +SL++ + L++ A V D TPLH A ++G C +LLL+AGA
Sbjct: 20 RTPVHEAAQRGESLQL-QQLIESGACVNQVTVDSITPLHAASLQGQARC--VQLLLAAGA 76
Query: 345 DPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
+A + G TPL A + CV LLL YG V
Sbjct: 77 QVDARNIDGSTPLCDACASGSIECVKLLLSYGAKV 111
Score = 39.5 bits (88), Expect = 0.043
Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
RTP+H A RG + + +L+ S GA N TPLH A+L + CV LLL G
Sbjct: 20 RTPVHEAAQRG-ESLQLQQLIES-GACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQ 77
Query: 379 VTLRTNGGVSAL 390
V R G + L
Sbjct: 78 VDARNIDGSTPL 89
>AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 97.1 bits (231), Expect = 2e-19
Identities = 61/174 (35%), Positives = 86/174 (49%), Gaps = 3/174 (1%)
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
E++ L+ G D T LH A+ G + KLL+ AGA+V A G TALHL
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGN-TALHL 60
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
A ++ H++ R+LL G+ D N G T LH+A L ++ +L+ V K+ G
Sbjct: 61 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
T LH A + +A++LL AGAD +N G TPL A + LLL
Sbjct: 121 DTALHVAAALNHK--KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLL 172
Score = 62.1 bits (144), Expect = 7e-09
Identities = 44/137 (32%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALH A+ G ++ A+LL+ GA++ N G T LHLA + +L+ +
Sbjct: 23 TALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADL 82
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
K+ G T LH + I RLLL+A + + G T LH+AA +LL
Sbjct: 83 KNNAGDTCLH--VAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILL 140
Query: 374 DYGGDVTLRTNGGVSAL 390
+ G D T+ N G + L
Sbjct: 141 EAGADTTIVNNAGQTPL 157
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/253 (26%), Positives = 97/253 (38%), Gaps = 6/253 (2%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
++ L+ G D D G T LH + G + KLL+ GA+ + + T A L
Sbjct: 3 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNT-ALHLA 61
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
C S V +L AD+ D LH A + +++ LL A
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTC-LHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
+T LHVAA+L K+LL AGAD G+ T L A + E A LL +
Sbjct: 121 DTALHVAAALNHKKVAKILLEAGADTTIVNNAGQ-TPLETARYHNNPEVALLLTKAPQVL 179
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ R L + + D A + + G TP V AR +
Sbjct: 180 RFSRGRSLRKKR-ERLKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAV--ARKEEAREE 236
Query: 339 LLSAGADPNAADN 351
LSA +P A D+
Sbjct: 237 FLSASPEPRAKDD 249
Score = 59.7 bits (138), Expect = 4e-08
Identities = 62/231 (26%), Positives = 92/231 (39%), Gaps = 6/231 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A W G S L+K G + + AG T LHL+C + ++LL G+
Sbjct: 23 TALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRA-- 80
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
D T LH AA L+ +++L+ V+ + + LH A + +V K L
Sbjct: 81 -DLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 139
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
LEAGA +TPL A + LL A +R + G E+
Sbjct: 140 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERR 199
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
A+ + D A G TP +A+ E E + + RAKD
Sbjct: 200 AQ--SVPRDEVAQSKGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD 248
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Query: 299 EVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
E++ L+ + +D DG T LH A G A+LL+ AGA+ A + G T LH
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQS--AKLLIKAGANVLAKNKAGNTALH 59
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+A N S +LL G L+ N G + L R I R L +VH +++
Sbjct: 60 LACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVH-EKNQ 118
Query: 419 LGD 421
GD
Sbjct: 119 AGD 121
>AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 97.1 bits (231), Expect = 2e-19
Identities = 61/174 (35%), Positives = 86/174 (49%), Gaps = 3/174 (1%)
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
E++ L+ G D T LH A+ G + KLL+ AGA+V A G TALHL
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGN-TALHL 60
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
A ++ H++ R+LL G+ D N G T LH+A L ++ +L+ V K+ G
Sbjct: 61 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
T LH A + +A++LL AGAD +N G TPL A + LLL
Sbjct: 121 DTALHVAAALNHK--KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLL 172
Score = 62.1 bits (144), Expect = 7e-09
Identities = 44/137 (32%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALH A+ G ++ A+LL+ GA++ N G T LHLA + +L+ +
Sbjct: 23 TALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADL 82
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
K+ G T LH + I RLLL+A + + G T LH+AA +LL
Sbjct: 83 KNNAGDTCLH--VAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILL 140
Query: 374 DYGGDVTLRTNGGVSAL 390
+ G D T+ N G + L
Sbjct: 141 EAGADTTIVNNAGQTPL 157
Score = 61.3 bits (142), Expect = 1e-08
Identities = 68/253 (26%), Positives = 97/253 (38%), Gaps = 6/253 (2%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
++ L+ G D D G T LH + G + KLL+ GA+ + + T A L
Sbjct: 3 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNT-ALHLA 61
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
C S V +L AD+ D LH A + +++ LL A
Sbjct: 62 CQNSHSQSTRVLLLAGSRADLKNNAGDTC-LHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
+T LHVAA+L K+LL AGAD G+ T L A + E A LL +
Sbjct: 121 DTALHVAAALNHKKVAKILLEAGADTTIVNNAGQ-TPLETARYHNNPEVALLLTKAPQVL 179
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ R L + + D A + + G TP V AR +
Sbjct: 180 RFSRGRSLRKKR-ERLKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAV--ARKEEAREE 236
Query: 339 LLSAGADPNAADN 351
LSA +P A D+
Sbjct: 237 FLSASPEPRAKDD 249
Score = 59.7 bits (138), Expect = 4e-08
Identities = 62/231 (26%), Positives = 92/231 (39%), Gaps = 6/231 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A W G S L+K G + + AG T LHL+C + ++LL G+
Sbjct: 23 TALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRA-- 80
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
D T LH AA L+ +++L+ V+ + + LH A + +V K L
Sbjct: 81 -DLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 139
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
LEAGA +TPL A + LL A +R + G E+
Sbjct: 140 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERR 199
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
A+ + D A G TP +A+ E E + + RAKD
Sbjct: 200 AQ--SVPRDEVAQSKGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD 248
Score = 50.4 bits (115), Expect = 2e-05
Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Query: 299 EVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
E++ L+ + +D DG T LH A G A+LL+ AGA+ A + G T LH
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQS--AKLLIKAGANVLAKNKAGNTALH 59
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+A N S +LL G L+ N G + L R I R L +VH +++
Sbjct: 60 LACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVH-EKNQ 118
Query: 419 LGD 421
GD
Sbjct: 119 AGD 121
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 96.7 bits (230), Expect = 3e-19
Identities = 102/395 (25%), Positives = 173/395 (43%), Gaps = 13/395 (3%)
Query: 19 SDESAHGADLAERLRVK-PSKDIWELDEIQYT-LRLLPYSEEISVLIGNGNYDETIQFAS 76
S+ SA D RL VK P K + D +Q+ ++ + +S N ++ +FA+
Sbjct: 242 SNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAA 301
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ +R L L +S L + + D LD+ + +++ V L
Sbjct: 302 RKKWKQSVRLISLCQR-LSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL 360
Query: 137 LDHGAHPNTWDSSTETK--ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAV 193
+ +D + K PL AA ++ +++LI G+ ++ + +++A
Sbjct: 361 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA 420
Query: 194 LSDAPEVVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ +K L E CP D E LHVAA G A +LL + G++ +
Sbjct: 421 RHGHVDTLKFLSE-NKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNI-QDKEE 478
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
T LH AA G+ A+ L + G +++ N G+TPL A+ ++VE L + AD+
Sbjct: 479 ETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 538
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D DG LH A+ R ++ + LLS G + D G TPLH+A + V+ L
Sbjct: 539 ACDKDGHIALHLAVRR--CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 373 LDYGGDVTLRTNGGVSALSFIVRR-VPDVIPRYLC 406
+ ++ + G + L + DV+ RYLC
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVV-RYLC 630
Score = 90.2 bits (214), Expect = 2e-17
Identities = 75/239 (31%), Positives = 102/239 (42%), Gaps = 5/239 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G A+ WA G L L + D D +G LH++ G + +LL G++
Sbjct: 411 GGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSN 470
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVV 201
PN D ET PLHCAA + K L G +VN +PL A ++V
Sbjct: 471 PNIQDKEEET---PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 527
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L E GA + LH+A K LL+ G V G T LH+A +
Sbjct: 528 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGN-TPLHVACK 586
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
DG+ L + ++D N G+TPLHLA L+VV L A V A DG+T
Sbjct: 587 DGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 88.6 bits (210), Expect = 7e-17
Identities = 78/282 (27%), Positives = 125/282 (44%), Gaps = 7/282 (2%)
Query: 109 DPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLAC 168
D ++ + G L ++ G+ + ++LL+ G+ + D + ++ AA +
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGG---SNAVYWAARHGHVDT 427
Query: 169 VKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
+K L + ++ S LH A +V + L G+ P+ ETPLH AA
Sbjct: 428 LKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAW 487
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
G S K L AG +V G+ T L A+ G+ + L +HGA ++ + G
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNREGE-TPLLTASARGYHDIVECLAEHGADLNACDKDGHI 546
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LHLA +EV++ L+ + V +D G TPLH A G +A L A + +
Sbjct: 547 ALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA--LCEANCNLD 604
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
++ +G TPLH+AA N V L G V T G +A
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTA 646
Score = 73.7 bits (173), Expect = 2e-12
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L G +P+ D T LH + G K L + G + N + ET PL A++
Sbjct: 464 LCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGET---PLLTASA 520
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V+ L HGAD+NA D LH AV EV+K LL G D TP
Sbjct: 521 RGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTP 580
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA G+ L A ++ + G+ T LHLAA +G + R L GA ++
Sbjct: 581 LHVACKDGNMPIVVALCEANCNLDISNKYGR-TPLHLAANNGILDVVRYLCLMGASVEAL 639
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
G+T LA Q V +L
Sbjct: 640 TTDGKTAEDLARSEQHEHVAGLL 662
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 96.7 bits (230), Expect = 3e-19
Identities = 102/395 (25%), Positives = 173/395 (43%), Gaps = 13/395 (3%)
Query: 19 SDESAHGADLAERLRVK-PSKDIWELDEIQYT-LRLLPYSEEISVLIGNGNYDETIQFAS 76
S+ SA D RL VK P K + D +Q+ ++ + +S N ++ +FA+
Sbjct: 242 SNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAA 301
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ +R L L +S L + + D LD+ + +++ V L
Sbjct: 302 RKKWKQSVRLISLCQR-LSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL 360
Query: 137 LDHGAHPNTWDSSTETK--ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAV 193
+ +D + K PL AA ++ +++LI G+ ++ + +++A
Sbjct: 361 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA 420
Query: 194 LSDAPEVVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ +K L E CP D E LHVAA G A +LL + G++ +
Sbjct: 421 RHGHVDTLKFLSE-NKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNI-QDKEE 478
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
T LH AA G+ A+ L + G +++ N G+TPL A+ ++VE L + AD+
Sbjct: 479 ETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 538
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D DG LH A+ R ++ + LLS G + D G TPLH+A + V+ L
Sbjct: 539 ACDKDGHIALHLAVRR--CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 373 LDYGGDVTLRTNGGVSALSFIVRR-VPDVIPRYLC 406
+ ++ + G + L + DV+ RYLC
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVV-RYLC 630
Score = 90.2 bits (214), Expect = 2e-17
Identities = 75/239 (31%), Positives = 102/239 (42%), Gaps = 5/239 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G A+ WA G L L + D D +G LH++ G + +LL G++
Sbjct: 411 GGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSN 470
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVV 201
PN D ET PLHCAA + K L G +VN +PL A ++V
Sbjct: 471 PNIQDKEEET---PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 527
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L E GA + LH+A K LL+ G V G T LH+A +
Sbjct: 528 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGN-TPLHVACK 586
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
DG+ L + ++D N G+TPLHLA L+VV L A V A DG+T
Sbjct: 587 DGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 88.6 bits (210), Expect = 7e-17
Identities = 78/282 (27%), Positives = 125/282 (44%), Gaps = 7/282 (2%)
Query: 109 DPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLAC 168
D ++ + G L ++ G+ + ++LL+ G+ + D + ++ AA +
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGG---SNAVYWAARHGHVDT 427
Query: 169 VKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
+K L + ++ S LH A +V + L G+ P+ ETPLH AA
Sbjct: 428 LKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAW 487
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
G S K L AG +V G+ T L A+ G+ + L +HGA ++ + G
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNREGE-TPLLTASARGYHDIVECLAEHGADLNACDKDGHI 546
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LHLA +EV++ L+ + V +D G TPLH A G +A L A + +
Sbjct: 547 ALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA--LCEANCNLD 604
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
++ +G TPLH+AA N V L G V T G +A
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTA 646
Score = 73.7 bits (173), Expect = 2e-12
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L G +P+ D T LH + G K L + G + N + ET PL A++
Sbjct: 464 LCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGET---PLLTASA 520
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V+ L HGAD+NA D LH AV EV+K LL G D TP
Sbjct: 521 RGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTP 580
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA G+ L A ++ + G+ T LHLAA +G + R L GA ++
Sbjct: 581 LHVACKDGNMPIVVALCEANCNLDISNKYGR-TPLHLAANNGILDVVRYLCLMGASVEAL 639
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
G+T LA Q V +L
Sbjct: 640 TTDGKTAEDLARSEQHEHVAGLL 662
>BC013172-1|AAH13172.1| 294|Homo sapiens ankyrin repeat and SOCS
box-containing 9 protein.
Length = 294
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/171 (37%), Positives = 80/171 (46%), Gaps = 5/171 (2%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
LH +CL G CVK+LL HGA N T TPL A + S CV +L+ HGA V
Sbjct: 73 LHEACLGGHLSCVKILLKHGAQVN---GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQ 129
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA 240
SP+H A E V L+ G D TPL++A +C K LL +
Sbjct: 130 PESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLES 189
Query: 241 GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
GADV G G+ + LH A E A LL+D GA N G+ P+ L
Sbjct: 190 GADVN--QGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVEL 238
Score = 93.9 bits (223), Expect = 2e-18
Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 9/204 (4%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
+H + + G + ++ L+ G N T +PLH A L+CVK+L+ HGA VN
Sbjct: 40 MHEAAIHGHQLSLRNLISQGWAVNI---ITADHVSPLHEACLGGHLSCVKILLKHGAQVN 96
Query: 181 AGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
+D +PL A +S + + V LL+ GA P+ +P+H AA G C L+
Sbjct: 97 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQ-PESDLASPIHEAARRGHVECVNSLIA 155
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSL 298
G ++ + T L+LA E+ C + LL+ GA ++ +GQ +PLH S
Sbjct: 156 YGGNIDHKIS-HLGTPLYLACENQQRACVKKLLESGADVN--QGKGQDSPLHAVARTASE 212
Query: 299 EVVEMLVDRCADVRAKDADGRTPL 322
E+ +L+D AD +AK+A+G+ P+
Sbjct: 213 ELACLLMDFGADTQAKNAEGKRPV 236
Score = 90.6 bits (215), Expect = 2e-17
Identities = 75/207 (36%), Positives = 102/207 (49%), Gaps = 8/207 (3%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+P+H AA ++ LI+ G VN +D SPLH A L VK LL+ GA +
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPL A GS C LLL GA V+ A+ +H AA GH EC L+
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESD--LASPIHEAARRGHVECVNSLIA 155
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTPLHGAIVRGARA 332
+G +ID TPL+LA Q V+ L++ ADV + K D +PLH A+ R A
Sbjct: 156 YGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQGKGQD--SPLH-AVARTASE 212
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHI 359
++A LL+ GAD A + G P+ +
Sbjct: 213 -ELACLLMDFGADTQAKNAEGKRPVEL 238
Score = 83.8 bits (198), Expect = 2e-15
Identities = 64/216 (29%), Positives = 91/216 (42%), Gaps = 5/216 (2%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
+SD SP+H A + ++ L+ G + +PLH A G SC K+LL GA
Sbjct: 34 VSDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGA 93
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
V T L A G +C LLL HGA + P +P+H A +E V
Sbjct: 94 QVNGVTADWH-TPLFNACVSGSWDCVNLLLQHGASVQ-PESDLASPIHEAARRGHVECVN 151
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
L+ ++ K + TPL+ A RAC + LL +GAD N +PLH A
Sbjct: 152 SLIAYGGNIDHKISHLGTPLYLACENQQRAC--VKKLLESGADVNQGKGQD-SPLHAVAR 208
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL+D+G D + G + + P
Sbjct: 209 TASEELACLLMDFGADTQAKNAEGKRPVELVPPESP 244
Score = 75.4 bits (177), Expect = 7e-13
Identities = 57/189 (30%), Positives = 89/189 (47%), Gaps = 5/189 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
+P+H AA G + L++ G V + LH A GH C ++LL HGA ++
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITAD-HVSPLHEACLGGHLSCVKILLKHGAQVN 96
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
TPL A ++ S + V +L+ A V+ ++D +P+H A RG C + L+
Sbjct: 97 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQP-ESDLASPIHEAARRGHVEC-VNSLI 154
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
G + + G TPL++A N+ ACV LL+ G DV + G S L + R +
Sbjct: 155 AYGGNIDHKISHLG-TPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLHAVARTASE 212
Query: 400 VIPRYLCKF 408
+ L F
Sbjct: 213 ELACLLMDF 221
Score = 74.5 bits (175), Expect = 1e-12
Identities = 57/164 (34%), Positives = 81/164 (49%), Gaps = 8/164 (4%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + LLK G + + T L +C+ GS +CV LLL HGA
Sbjct: 76 ACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASV----QPE 131
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
A+P+H AA + CV LIA+G +++ +S +PL+ A + VK+LLE+GA
Sbjct: 132 SDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGA 191
Query: 210 CPDTPQ-VFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
D Q ++PLH A S LL++ GAD +A GK
Sbjct: 192 --DVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGK 233
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 96.7 bits (230), Expect = 3e-19
Identities = 102/395 (25%), Positives = 173/395 (43%), Gaps = 13/395 (3%)
Query: 19 SDESAHGADLAERLRVK-PSKDIWELDEIQYT-LRLLPYSEEISVLIGNGNYDETIQFAS 76
S+ SA D RL VK P K + D +Q+ ++ + +S N ++ +FA+
Sbjct: 242 SNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAA 301
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ +R L L +S L + + D LD+ + +++ V L
Sbjct: 302 RKKWKQSVRLISLCQR-LSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL 360
Query: 137 LDHGAHPNTWDSSTETK--ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAV 193
+ +D + K PL AA ++ +++LI G+ ++ + +++A
Sbjct: 361 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA 420
Query: 194 LSDAPEVVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ +K L E CP D E LHVAA G A +LL + G++ +
Sbjct: 421 RHGHVDTLKFLSE-NKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNI-QDKEE 478
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
T LH AA G+ A+ L + G +++ N G+TPL A+ ++VE L + AD+
Sbjct: 479 ETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 538
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D DG LH A+ R ++ + LLS G + D G TPLH+A + V+ L
Sbjct: 539 ACDKDGHIALHLAVRR--CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 373 LDYGGDVTLRTNGGVSALSFIVRR-VPDVIPRYLC 406
+ ++ + G + L + DV+ RYLC
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVV-RYLC 630
Score = 90.2 bits (214), Expect = 2e-17
Identities = 75/239 (31%), Positives = 102/239 (42%), Gaps = 5/239 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G A+ WA G L L + D D +G LH++ G + +LL G++
Sbjct: 411 GGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSN 470
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVV 201
PN D ET PLHCAA + K L G +VN +PL A ++V
Sbjct: 471 PNIQDKEEET---PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 527
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L E GA + LH+A K LL+ G V G T LH+A +
Sbjct: 528 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGN-TPLHVACK 586
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
DG+ L + ++D N G+TPLHLA L+VV L A V A DG+T
Sbjct: 587 DGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 88.6 bits (210), Expect = 7e-17
Identities = 78/282 (27%), Positives = 125/282 (44%), Gaps = 7/282 (2%)
Query: 109 DPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLAC 168
D ++ + G L ++ G+ + ++LL+ G+ + D + ++ AA +
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGG---SNAVYWAARHGHVDT 427
Query: 169 VKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
+K L + ++ S LH A +V + L G+ P+ ETPLH AA
Sbjct: 428 LKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAW 487
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
G S K L AG +V G+ T L A+ G+ + L +HGA ++ + G
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNREGE-TPLLTASARGYHDIVECLAEHGADLNACDKDGHI 546
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LHLA +EV++ L+ + V +D G TPLH A G +A L A + +
Sbjct: 547 ALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA--LCEANCNLD 604
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
++ +G TPLH+AA N V L G V T G +A
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTA 646
Score = 73.7 bits (173), Expect = 2e-12
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L G +P+ D T LH + G K L + G + N + ET PL A++
Sbjct: 464 LCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGET---PLLTASA 520
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V+ L HGAD+NA D LH AV EV+K LL G D TP
Sbjct: 521 RGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTP 580
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA G+ L A ++ + G+ T LHLAA +G + R L GA ++
Sbjct: 581 LHVACKDGNMPIVVALCEANCNLDISNKYGR-TPLHLAANNGILDVVRYLCLMGASVEAL 639
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
G+T LA Q V +L
Sbjct: 640 TTDGKTAEDLARSEQHEHVAGLL 662
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 96.7 bits (230), Expect = 3e-19
Identities = 102/395 (25%), Positives = 173/395 (43%), Gaps = 13/395 (3%)
Query: 19 SDESAHGADLAERLRVK-PSKDIWELDEIQYT-LRLLPYSEEISVLIGNGNYDETIQFAS 76
S+ SA D RL VK P K + D +Q+ ++ + +S N ++ +FA+
Sbjct: 242 SNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAA 301
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ +R L L +S L + + D LD+ + +++ V L
Sbjct: 302 RKKWKQSVRLISLCQR-LSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL 360
Query: 137 LDHGAHPNTWDSSTETK--ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAV 193
+ +D + K PL AA ++ +++LI G+ ++ + +++A
Sbjct: 361 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA 420
Query: 194 LSDAPEVVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ +K L E CP D E LHVAA G A +LL + G++ +
Sbjct: 421 RHGHVDTLKFLSE-NKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNI-QDKEE 478
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
T LH AA G+ A+ L + G +++ N G+TPL A+ ++VE L + AD+
Sbjct: 479 ETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 538
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D DG LH A+ R ++ + LLS G + D G TPLH+A + V+ L
Sbjct: 539 ACDKDGHIALHLAVRR--CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 373 LDYGGDVTLRTNGGVSALSFIVRR-VPDVIPRYLC 406
+ ++ + G + L + DV+ RYLC
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVV-RYLC 630
Score = 90.2 bits (214), Expect = 2e-17
Identities = 75/239 (31%), Positives = 102/239 (42%), Gaps = 5/239 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G A+ WA G L L + D D +G LH++ G + +LL G++
Sbjct: 411 GGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSN 470
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVV 201
PN D ET PLHCAA + K L G +VN +PL A ++V
Sbjct: 471 PNIQDKEEET---PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 527
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L E GA + LH+A K LL+ G V G T LH+A +
Sbjct: 528 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGN-TPLHVACK 586
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
DG+ L + ++D N G+TPLHLA L+VV L A V A DG+T
Sbjct: 587 DGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 88.6 bits (210), Expect = 7e-17
Identities = 78/282 (27%), Positives = 125/282 (44%), Gaps = 7/282 (2%)
Query: 109 DPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLAC 168
D ++ + G L ++ G+ + ++LL+ G+ + D + ++ AA +
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGG---SNAVYWAARHGHVDT 427
Query: 169 VKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
+K L + ++ S LH A +V + L G+ P+ ETPLH AA
Sbjct: 428 LKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAW 487
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
G S K L AG +V G+ T L A+ G+ + L +HGA ++ + G
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNREGE-TPLLTASARGYHDIVECLAEHGADLNACDKDGHI 546
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LHLA +EV++ L+ + V +D G TPLH A G +A L A + +
Sbjct: 547 ALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA--LCEANCNLD 604
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
++ +G TPLH+AA N V L G V T G +A
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTA 646
Score = 73.7 bits (173), Expect = 2e-12
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L G +P+ D T LH + G K L + G + N + ET PL A++
Sbjct: 464 LCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGET---PLLTASA 520
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V+ L HGAD+NA D LH AV EV+K LL G D TP
Sbjct: 521 RGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTP 580
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA G+ L A ++ + G+ T LHLAA +G + R L GA ++
Sbjct: 581 LHVACKDGNMPIVVALCEANCNLDISNKYGR-TPLHLAANNGILDVVRYLCLMGASVEAL 639
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
G+T LA Q V +L
Sbjct: 640 TTDGKTAEDLARSEQHEHVAGLL 662
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 96.7 bits (230), Expect = 3e-19
Identities = 102/395 (25%), Positives = 173/395 (43%), Gaps = 13/395 (3%)
Query: 19 SDESAHGADLAERLRVK-PSKDIWELDEIQYT-LRLLPYSEEISVLIGNGNYDETIQFAS 76
S+ SA D RL VK P K + D +Q+ ++ + +S N ++ +FA+
Sbjct: 242 SNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAA 301
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ +R L L +S L + + D LD+ + +++ V L
Sbjct: 302 RKKWKQSVRLISLCQR-LSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL 360
Query: 137 LDHGAHPNTWDSSTETK--ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAV 193
+ +D + K PL AA ++ +++LI G+ ++ + +++A
Sbjct: 361 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA 420
Query: 194 LSDAPEVVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ +K L E CP D E LHVAA G A +LL + G++ +
Sbjct: 421 RHGHVDTLKFLSE-NKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNI-QDKEE 478
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
T LH AA G+ A+ L + G +++ N G+TPL A+ ++VE L + AD+
Sbjct: 479 ETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 538
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D DG LH A+ R ++ + LLS G + D G TPLH+A + V+ L
Sbjct: 539 ACDKDGHIALHLAVRR--CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 596
Query: 373 LDYGGDVTLRTNGGVSALSFIVRR-VPDVIPRYLC 406
+ ++ + G + L + DV+ RYLC
Sbjct: 597 CEANCNLDISNKYGRTPLHLAANNGILDVV-RYLC 630
Score = 90.2 bits (214), Expect = 2e-17
Identities = 75/239 (31%), Positives = 102/239 (42%), Gaps = 5/239 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G A+ WA G L L + D D +G LH++ G + +LL G++
Sbjct: 411 GGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSN 470
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVV 201
PN D ET PLHCAA + K L G +VN +PL A ++V
Sbjct: 471 PNIQDKEEET---PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 527
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L E GA + LH+A K LL+ G V G T LH+A +
Sbjct: 528 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGN-TPLHVACK 586
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
DG+ L + ++D N G+TPLHLA L+VV L A V A DG+T
Sbjct: 587 DGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 88.6 bits (210), Expect = 7e-17
Identities = 78/282 (27%), Positives = 125/282 (44%), Gaps = 7/282 (2%)
Query: 109 DPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLAC 168
D ++ + G L ++ G+ + ++LL+ G+ + D + ++ AA +
Sbjct: 371 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGG---SNAVYWAARHGHVDT 427
Query: 169 VKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
+K L + ++ S LH A +V + L G+ P+ ETPLH AA
Sbjct: 428 LKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAW 487
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
G S K L AG +V G+ T L A+ G+ + L +HGA ++ + G
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNREGE-TPLLTASARGYHDIVECLAEHGADLNACDKDGHI 546
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LHLA +EV++ L+ + V +D G TPLH A G +A L A + +
Sbjct: 547 ALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA--LCEANCNLD 604
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
++ +G TPLH+AA N V L G V T G +A
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTA 646
Score = 73.7 bits (173), Expect = 2e-12
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L G +P+ D T LH + G K L + G + N + ET PL A++
Sbjct: 464 LCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGET---PLLTASA 520
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V+ L HGAD+NA D LH AV EV+K LL G D TP
Sbjct: 521 RGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTP 580
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA G+ L A ++ + G+ T LHLAA +G + R L GA ++
Sbjct: 581 LHVACKDGNMPIVVALCEANCNLDISNKYGR-TPLHLAANNGILDVVRYLCLMGASVEAL 639
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
G+T LA Q V +L
Sbjct: 640 TTDGKTAEDLARSEQHEHVAGLL 662
>AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein
protein.
Length = 641
Score = 96.7 bits (230), Expect = 3e-19
Identities = 61/174 (35%), Positives = 86/174 (49%), Gaps = 3/174 (1%)
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
E++ L+ G D T LH A+ G + KLL+ AGA+V A G TALHL
Sbjct: 3 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGN-TALHL 61
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
A ++ H++ R+LL G+ D N G T LH+A L ++ +L+ V K+ G
Sbjct: 62 ACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 121
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
T LH A + +A++LL AGAD +N G TPL A + LLL
Sbjct: 122 DTALHVAAALNHK--KVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLL 173
Score = 61.7 bits (143), Expect = 9e-09
Identities = 44/137 (32%), Positives = 65/137 (47%), Gaps = 2/137 (1%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
TALH A+ G ++ A+LL+ GA++ N G T LHLA + +L+ +
Sbjct: 24 TALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADL 83
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
K+ G T LH + I RLLL+A + + G T LH+AA +LL
Sbjct: 84 KNNAGDTCLH--VAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILL 141
Query: 374 DYGGDVTLRTNGGVSAL 390
+ G D T+ N G + L
Sbjct: 142 EAGADTTIVNNAGQTPL 158
Score = 60.9 bits (141), Expect = 2e-08
Identities = 68/253 (26%), Positives = 97/253 (38%), Gaps = 6/253 (2%)
Query: 99 LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLH 158
++ L+ G D D G T LH + G + KLL+ GA+ + + T A L
Sbjct: 4 IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNT-ALHLA 62
Query: 159 CAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
C S V +L AD+ D LH A + +++ LL A
Sbjct: 63 CQNSHSQSTRVLLLAGSRADLKNNAGDTC-LHVAARYNHLSIIRLLLTAFCSVHEKNQAG 121
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHI 278
+T LHVAA+L K+LL AGAD G+ T L A + E A LL +
Sbjct: 122 DTALHVAAALNHKKVAKILLEAGADTTIVNNAGQ-TPLETARYHNNPEVALLLTKAPQVL 180
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ R L + + D A + + G TP V AR +
Sbjct: 181 RFSRGRSLRKKR-ERLKEERRAQSVPRDEVAQSKGSVSAGDTPSSEQAV--ARKEEAREE 237
Query: 339 LLSAGADPNAADN 351
LSA +P A D+
Sbjct: 238 FLSASPEPRAKDD 250
Score = 59.3 bits (137), Expect = 5e-08
Identities = 62/231 (26%), Positives = 92/231 (39%), Gaps = 6/231 (2%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A W G S L+K G + + AG T LHL+C + ++LL G+
Sbjct: 24 TALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRA-- 81
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKEL 204
D T LH AA L+ +++L+ V+ + + LH A + +V K L
Sbjct: 82 -DLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKIL 140
Query: 205 LEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGH 264
LEAGA +TPL A + LL A +R + G E+
Sbjct: 141 LEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERR 200
Query: 265 AECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
A+ + D A G TP +A+ E E + + RAKD
Sbjct: 201 AQ--SVPRDEVAQSKGSVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKD 249
Score = 50.0 bits (114), Expect = 3e-05
Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Query: 299 EVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
E++ L+ + +D DG T LH A G A+LL+ AGA+ A + G T LH
Sbjct: 3 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQS--AKLLVKAGANVLAKNKAGNTALH 60
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHVSEHE 418
+A N S +LL G L+ N G + L R I R L +VH +++
Sbjct: 61 LACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVH-EKNQ 119
Query: 419 LGD 421
GD
Sbjct: 120 AGD 122
>AK000643-1|BAA91302.1| 262|Homo sapiens protein ( Homo sapiens
cDNA FLJ20636 fis, clone KAT03434. ).
Length = 262
Score = 96.7 bits (230), Expect = 3e-19
Identities = 64/171 (37%), Positives = 80/171 (46%), Gaps = 5/171 (2%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
LH +CL G CVK+LL HGA N T TPL A + S CV +L+ HGA V
Sbjct: 73 LHEACLGGHLSCVKILLKHGAQVN---GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQ 129
Query: 181 AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNA 240
SP+H A E V L+ G D TPL++A +C K LL +
Sbjct: 130 PESDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLES 189
Query: 241 GADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHL 291
GADV G G+ + LH A E A LL+D GA N G+ P+ L
Sbjct: 190 GADVN--QGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGKRPVEL 238
Score = 93.9 bits (223), Expect = 2e-18
Identities = 65/204 (31%), Positives = 105/204 (51%), Gaps = 9/204 (4%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
+H + + G + ++ L+ G N T +PLH A L+CVK+L+ HGA VN
Sbjct: 40 MHEAAIHGHQLSLRNLISQGWAVNI---ITADHVSPLHEACLGGHLSCVKILLKHGAQVN 96
Query: 181 AGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
+D +PL A +S + + V LL+ GA P+ +P+H AA G C L+
Sbjct: 97 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQ-PESDLASPIHEAARRGHVECVNSLIA 155
Query: 240 AGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQ-TPLHLATLAQSL 298
G ++ + T L+LA E+ C + LL+ GA ++ +GQ +PLH S
Sbjct: 156 YGGNIDHKIS-HLGTPLYLACENQQRACVKKLLESGADVN--QGKGQDSPLHAVARTASE 212
Query: 299 EVVEMLVDRCADVRAKDADGRTPL 322
E+ +L+D AD +AK+A+G+ P+
Sbjct: 213 ELACLLMDFGADTQAKNAEGKRPV 236
Score = 90.6 bits (215), Expect = 2e-17
Identities = 75/207 (36%), Positives = 102/207 (49%), Gaps = 8/207 (3%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
+P+H AA ++ LI+ G VN +D SPLH A L VK LL+ GA +
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGAQVNG 97
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
TPL A GS C LLL GA V+ A+ +H AA GH EC L+
Sbjct: 98 VTADWHTPLFNACVSGSWDCVNLLLQHGASVQPESD--LASPIHEAARRGHVECVNSLIA 155
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTPLHGAIVRGARA 332
+G +ID TPL+LA Q V+ L++ ADV + K D +PLH A+ R A
Sbjct: 156 YGGNIDHKISHLGTPLYLACENQQRACVKKLLESGADVNQGKGQD--SPLH-AVARTASE 212
Query: 333 CDIARLLLSAGADPNAADNFGYTPLHI 359
++A LL+ GAD A + G P+ +
Sbjct: 213 -ELACLLMDFGADTQAKNAEGKRPVEL 238
Score = 83.8 bits (198), Expect = 2e-15
Identities = 64/216 (29%), Positives = 91/216 (42%), Gaps = 5/216 (2%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
+SD SP+H A + ++ L+ G + +PLH A G SC K+LL GA
Sbjct: 34 VSDWSPMHEAAIHGHQLSLRNLISQGWAVNIITADHVSPLHEACLGGHLSCVKILLKHGA 93
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
V T L A G +C LLL HGA + P +P+H A +E V
Sbjct: 94 QVNGVTADWH-TPLFNACVSGSWDCVNLLLQHGASVQ-PESDLASPIHEAARRGHVECVN 151
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
L+ ++ K + TPL+ A RAC + LL +GAD N +PLH A
Sbjct: 152 SLIAYGGNIDHKISHLGTPLYLACENQQRAC--VKKLLESGADVNQGKGQD-SPLHAVAR 208
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL+D+G D + G + + P
Sbjct: 209 TASEELACLLMDFGADTQAKNAEGKRPVELVPPESP 244
Score = 75.4 bits (177), Expect = 7e-13
Identities = 57/189 (30%), Positives = 89/189 (47%), Gaps = 5/189 (2%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHID 279
+P+H AA G + L++ G V + LH A GH C ++LL HGA ++
Sbjct: 38 SPMHEAAIHGHQLSLRNLISQGWAVNIITAD-HVSPLHEACLGGHLSCVKILLKHGAQVN 96
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
TPL A ++ S + V +L+ A V+ ++D +P+H A RG C + L+
Sbjct: 97 GVTADWHTPLFNACVSGSWDCVNLLLQHGASVQP-ESDLASPIHEAARRGHVEC-VNSLI 154
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
G + + G TPL++A N+ ACV LL+ G DV + G S L + R +
Sbjct: 155 AYGGNIDHKISHLG-TPLYLACENQQRACVKKLLESGADVN-QGKGQDSPLHAVARTASE 212
Query: 400 VIPRYLCKF 408
+ L F
Sbjct: 213 ELACLLMDF 221
Score = 74.5 bits (175), Expect = 1e-12
Identities = 57/164 (34%), Positives = 81/164 (49%), Gaps = 8/164 (4%)
Query: 91 ACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSST 150
AC G + LLK G + + T L +C+ GS +CV LLL HGA
Sbjct: 76 ACLGGHLSCVKILLKHGAQVNGVTADWHTPLFNACVSGSWDCVNLLLQHGASV----QPE 131
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGA 209
A+P+H AA + CV LIA+G +++ +S +PL+ A + VK+LLE+GA
Sbjct: 132 SDLASPIHEAARRGHVECVNSLIAYGGNIDHKISHLGTPLYLACENQQRACVKKLLESGA 191
Query: 210 CPDTPQ-VFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
D Q ++PLH A S LL++ GAD +A GK
Sbjct: 192 --DVNQGKGQDSPLHAVARTASEELACLLMDFGADTQAKNAEGK 233
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 96.7 bits (230), Expect = 3e-19
Identities = 102/395 (25%), Positives = 173/395 (43%), Gaps = 13/395 (3%)
Query: 19 SDESAHGADLAERLRVK-PSKDIWELDEIQYT-LRLLPYSEEISVLIGNGNYDETIQFAS 76
S+ SA D RL VK P K + D +Q+ ++ + +S N ++ +FA+
Sbjct: 245 SNTSALAKDFIRRLLVKDPKKRMTIQDSLQHPWIKPKDTQQALSRKASAVNMEKFKKFAA 304
Query: 77 EAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLL 136
+ +R L L +S L + + D LD+ + +++ V L
Sbjct: 305 RKKWKQSVRLISLCQR-LSRSFLSRSNMSVARSDDTLDEEDSFVMKAIIHAINDDNVPGL 363
Query: 137 LDHGAHPNTWDSSTETK--ATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAV 193
+ +D + K PL AA ++ +++LI G+ ++ + +++A
Sbjct: 364 QHLLGSLSNYDVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAA 423
Query: 194 LSDAPEVVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGK 252
+ +K L E CP D E LHVAA G A +LL + G++ +
Sbjct: 424 RHGHVDTLKFLSE-NKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNI-QDKEE 481
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVR 312
T LH AA G+ A+ L + G +++ N G+TPL A+ ++VE L + AD+
Sbjct: 482 ETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 541
Query: 313 AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
A D DG LH A+ R ++ + LLS G + D G TPLH+A + V+ L
Sbjct: 542 ACDKDGHIALHLAVRR--CQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVAL 599
Query: 373 LDYGGDVTLRTNGGVSALSFIVRR-VPDVIPRYLC 406
+ ++ + G + L + DV+ RYLC
Sbjct: 600 CEANCNLDISNKYGRTPLHLAANNGILDVV-RYLC 633
Score = 90.2 bits (214), Expect = 2e-17
Identities = 75/239 (31%), Positives = 102/239 (42%), Gaps = 5/239 (2%)
Query: 83 GLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
G A+ WA G L L + D D +G LH++ G + +LL G++
Sbjct: 414 GGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSN 473
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVV 201
PN D ET PLHCAA + K L G +VN +PL A ++V
Sbjct: 474 PNIQDKEEET---PLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIV 530
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ L E GA + LH+A K LL+ G V G T LH+A +
Sbjct: 531 ECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGN-TPLHVACK 589
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRT 320
DG+ L + ++D N G+TPLHLA L+VV L A V A DG+T
Sbjct: 590 DGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 648
Score = 88.6 bits (210), Expect = 7e-17
Identities = 78/282 (27%), Positives = 125/282 (44%), Gaps = 7/282 (2%)
Query: 109 DPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLAC 168
D ++ + G L ++ G+ + ++LL+ G+ + D + ++ AA +
Sbjct: 374 DVNQPNKHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGG---SNAVYWAARHGHVDT 430
Query: 169 VKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAAS 227
+K L + ++ S LH A +V + L G+ P+ ETPLH AA
Sbjct: 431 LKFLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAW 490
Query: 228 LGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQT 287
G S K L AG +V G+ T L A+ G+ + L +HGA ++ + G
Sbjct: 491 HGYYSVAKALCEAGCNVNIKNREGE-TPLLTASARGYHDIVECLAEHGADLNACDKDGHI 549
Query: 288 PLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPN 347
LHLA +EV++ L+ + V +D G TPLH A G +A L A + +
Sbjct: 550 ALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVA--LCEANCNLD 607
Query: 348 AADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSA 389
++ +G TPLH+AA N V L G V T G +A
Sbjct: 608 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTA 649
Score = 73.7 bits (173), Expect = 2e-12
Identities = 65/203 (32%), Positives = 87/203 (42%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
L G +P+ D T LH + G K L + G + N + ET PL A++
Sbjct: 467 LCSFGSNPNIQDKEEETPLHCAAWHGYYSVAKALCEAGCNVNIKNREGET---PLLTASA 523
Query: 163 AKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
V+ L HGAD+NA D LH AV EV+K LL G D TP
Sbjct: 524 RGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTP 583
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LHVA G+ L A ++ + G+ T LHLAA +G + R L GA ++
Sbjct: 584 LHVACKDGNMPIVVALCEANCNLDISNKYGR-TPLHLAANNGILDVVRYLCLMGASVEAL 642
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
G+T LA Q V +L
Sbjct: 643 TTDGKTAEDLARSEQHEHVAGLL 665
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 96.3 bits (229), Expect = 4e-19
Identities = 65/197 (32%), Positives = 96/197 (48%), Gaps = 3/197 (1%)
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
DA +V L + GA +T H+AA+ G C ++++ G DV A G +A
Sbjct: 31 DAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGH-SA 89
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
LHLAA++ H EC R LL + + G+T LH A L+ V++L + + + KD
Sbjct: 90 LHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKD 149
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG PL A+ G +I LL GAD N+ + G T L +A S V L+
Sbjct: 150 LDGNIPLLLAVQNG--HSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 207
Query: 376 GGDVTLRTNGGVSALSF 392
G D+ L + G +AL +
Sbjct: 208 GADLNLVDSLGYNALHY 224
Score = 91.9 bits (218), Expect = 8e-18
Identities = 62/196 (31%), Positives = 95/196 (48%), Gaps = 5/196 (2%)
Query: 129 SEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRS 187
+E+ LL GA DS +T H AA+ + C++V+I HG DV A + S
Sbjct: 32 AEKVASLLGKKGASATKHDSEGKTA---FHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 88
Query: 188 PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAA 247
LH A + E +++LL++ ++ +T LH AA+ G ++L + +
Sbjct: 89 ALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 148
Query: 248 MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDR 307
G L LA ++GH+E LLDHGA ++ N G+T L LA S VE L+ +
Sbjct: 149 DLDGNIPLL-LAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 207
Query: 308 CADVRAKDADGRTPLH 323
AD+ D+ G LH
Sbjct: 208 GADLNLVDSLGYNALH 223
Score = 84.2 bits (199), Expect = 2e-15
Identities = 59/218 (27%), Positives = 101/218 (46%), Gaps = 9/218 (4%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K G + D G+T HL+ G EC+++++ HG D+ T + LH AA
Sbjct: 41 KKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDT---TGHSALHLAAKNS 97
Query: 165 SLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
C++ L+ + S ++ LHYA + V+ L E + + + PL
Sbjct: 98 HHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLL 157
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
+A G + LL+ GADV + G+ TAL LA E G + L+ GA ++ +
Sbjct: 158 LAVQNGHSEICHFLLDHGADVNSRNKSGR-TALMLACEIGSSNAVEALIKKGADLNLVDS 216
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
G LH + L+++ + +L+ + ++DAD +TP
Sbjct: 217 LGYNALHYSKLSENAGIQSLLLSKI----SQDADLKTP 250
Score = 83.0 bits (196), Expect = 3e-15
Identities = 58/199 (29%), Positives = 89/199 (44%), Gaps = 4/199 (2%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
++ H A E ++ ++ G + LH+AA C + LL +
Sbjct: 54 KTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAE 113
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
+ GK TALH AA G + ++L +H + I+ + G PL LA E+ L+
Sbjct: 114 SVDSSGK-TALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 172
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
D ADV +++ GRT L A G+ + L+ GAD N D+ GY LH + L+E
Sbjct: 173 DHGADVNSRNKSGRTALMLACEIGSS--NAVEALIKKGADLNLVDSLGYNALHYSKLSEN 230
Query: 366 SACVLLLLD-YGGDVTLRT 383
+ LLL D L+T
Sbjct: 231 AGIQSLLLSKISQDADLKT 249
Score = 69.7 bits (163), Expect = 3e-11
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 12/218 (5%)
Query: 56 SEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDD 115
+E+++ L+G T ++EG +TA A G L ++ GVD D
Sbjct: 32 AEKVASLLGKKGASAT---KHDSEG----KTAFHLAAAKGHVECLRVMITHGVDVTAQDT 84
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL+ EC++ LL + DSS + T LH AA+ L V++L H
Sbjct: 85 TGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGK---TALHYAAAQGCLQAVQILCEH 141
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
+ +N L PL AV + E+ LL+ GA ++ T L +A +GS++
Sbjct: 142 KSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAV 201
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ L+ GAD+ G ALH + +A LLL
Sbjct: 202 EALIKKGADLNLVDSLG-YNALHYSKLSENAGIQSLLL 238
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Query: 259 AAEDGHAE-CARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
A E+G AE A LL GA + G+T HLA +E + +++ DV A+D
Sbjct: 26 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 85
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A C R LL + + D+ G T LH AA V +L ++
Sbjct: 86 GHSALHLAAKNSHHEC--IRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 143
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYL 405
+ L+ G L V+ I +L
Sbjct: 144 PINLKDLDGNIPLLLAVQNGHSEICHFL 171
>AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 14
isoform protein.
Length = 972
Score = 96.3 bits (229), Expect = 4e-19
Identities = 65/197 (32%), Positives = 96/197 (48%), Gaps = 3/197 (1%)
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
DA +V L + GA +T H+AA+ G C ++++ G DV A G +A
Sbjct: 23 DAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGH-SA 81
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
LHLAA++ H EC R LL + + G+T LH A L+ V++L + + + KD
Sbjct: 82 LHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKD 141
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG PL A+ G +I LL GAD N+ + G T L +A S V L+
Sbjct: 142 LDGNIPLLLAVQNG--HSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 199
Query: 376 GGDVTLRTNGGVSALSF 392
G D+ L + G +AL +
Sbjct: 200 GADLNLVDSLGYNALHY 216
Score = 91.9 bits (218), Expect = 8e-18
Identities = 62/196 (31%), Positives = 95/196 (48%), Gaps = 5/196 (2%)
Query: 129 SEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRS 187
+E+ LL GA DS +T H AA+ + C++V+I HG DV A + S
Sbjct: 24 AEKVASLLGKKGASATKHDSEGKTA---FHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 80
Query: 188 PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAA 247
LH A + E +++LL++ ++ +T LH AA+ G ++L + +
Sbjct: 81 ALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 140
Query: 248 MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDR 307
G L LA ++GH+E LLDHGA ++ N G+T L LA S VE L+ +
Sbjct: 141 DLDGNIPLL-LAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 199
Query: 308 CADVRAKDADGRTPLH 323
AD+ D+ G LH
Sbjct: 200 GADLNLVDSLGYNALH 215
Score = 84.2 bits (199), Expect = 2e-15
Identities = 59/218 (27%), Positives = 101/218 (46%), Gaps = 9/218 (4%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K G + D G+T HL+ G EC+++++ HG D+ T + LH AA
Sbjct: 33 KKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDT---TGHSALHLAAKNS 89
Query: 165 SLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
C++ L+ + S ++ LHYA + V+ L E + + + PL
Sbjct: 90 HHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLL 149
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
+A G + LL+ GADV + G+ TAL LA E G + L+ GA ++ +
Sbjct: 150 LAVQNGHSEICHFLLDHGADVNSRNKSGR-TALMLACEIGSSNAVEALIKKGADLNLVDS 208
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
G LH + L+++ + +L+ + ++DAD +TP
Sbjct: 209 LGYNALHYSKLSENAGIQSLLLSKI----SQDADLKTP 242
Score = 83.0 bits (196), Expect = 3e-15
Identities = 58/199 (29%), Positives = 89/199 (44%), Gaps = 4/199 (2%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
++ H A E ++ ++ G + LH+AA C + LL +
Sbjct: 46 KTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAE 105
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
+ GK TALH AA G + ++L +H + I+ + G PL LA E+ L+
Sbjct: 106 SVDSSGK-TALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 164
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
D ADV +++ GRT L A G+ + L+ GAD N D+ GY LH + L+E
Sbjct: 165 DHGADVNSRNKSGRTALMLACEIGSS--NAVEALIKKGADLNLVDSLGYNALHYSKLSEN 222
Query: 366 SACVLLLLD-YGGDVTLRT 383
+ LLL D L+T
Sbjct: 223 AGIQSLLLSKISQDADLKT 241
Score = 69.7 bits (163), Expect = 3e-11
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 12/218 (5%)
Query: 56 SEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDD 115
+E+++ L+G T ++EG +TA A G L ++ GVD D
Sbjct: 24 AEKVASLLGKKGASAT---KHDSEG----KTAFHLAAAKGHVECLRVMITHGVDVTAQDT 76
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL+ EC++ LL + DSS + T LH AA+ L V++L H
Sbjct: 77 TGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGK---TALHYAAAQGCLQAVQILCEH 133
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
+ +N L PL AV + E+ LL+ GA ++ T L +A +GS++
Sbjct: 134 KSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAV 193
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ L+ GAD+ G ALH + +A LLL
Sbjct: 194 EALIKKGADLNLVDSLG-YNALHYSKLSENAGIQSLLL 230
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Query: 259 AAEDGHAE-CARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
A E+G AE A LL GA + G+T HLA +E + +++ DV A+D
Sbjct: 18 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 77
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A C R LL + + D+ G T LH AA V +L ++
Sbjct: 78 GHSALHLAAKNSHHEC--IRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 135
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYL 405
+ L+ G L V+ I +L
Sbjct: 136 PINLKDLDGNIPLLLAVQNGHSEICHFL 163
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 96.3 bits (229), Expect = 4e-19
Identities = 65/197 (32%), Positives = 96/197 (48%), Gaps = 3/197 (1%)
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
DA +V L + GA +T H+AA+ G C ++++ G DV A G +A
Sbjct: 34 DAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGH-SA 92
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
LHLAA++ H EC R LL + + G+T LH A L+ V++L + + + KD
Sbjct: 93 LHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKD 152
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG PL A+ G +I LL GAD N+ + G T L +A S V L+
Sbjct: 153 LDGNIPLLLAVQNG--HSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 210
Query: 376 GGDVTLRTNGGVSALSF 392
G D+ L + G +AL +
Sbjct: 211 GADLNLVDSLGYNALHY 227
Score = 91.9 bits (218), Expect = 8e-18
Identities = 62/196 (31%), Positives = 95/196 (48%), Gaps = 5/196 (2%)
Query: 129 SEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRS 187
+E+ LL GA DS +T H AA+ + C++V+I HG DV A + S
Sbjct: 35 AEKVASLLGKKGASATKHDSEGKTA---FHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 91
Query: 188 PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAA 247
LH A + E +++LL++ ++ +T LH AA+ G ++L + +
Sbjct: 92 ALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 151
Query: 248 MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDR 307
G L LA ++GH+E LLDHGA ++ N G+T L LA S VE L+ +
Sbjct: 152 DLDGNIPLL-LAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 210
Query: 308 CADVRAKDADGRTPLH 323
AD+ D+ G LH
Sbjct: 211 GADLNLVDSLGYNALH 226
Score = 84.2 bits (199), Expect = 2e-15
Identities = 59/218 (27%), Positives = 101/218 (46%), Gaps = 9/218 (4%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K G + D G+T HL+ G EC+++++ HG D+ T + LH AA
Sbjct: 44 KKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDT---TGHSALHLAAKNS 100
Query: 165 SLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
C++ L+ + S ++ LHYA + V+ L E + + + PL
Sbjct: 101 HHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLL 160
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
+A G + LL+ GADV + G+ TAL LA E G + L+ GA ++ +
Sbjct: 161 LAVQNGHSEICHFLLDHGADVNSRNKSGR-TALMLACEIGSSNAVEALIKKGADLNLVDS 219
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
G LH + L+++ + +L+ + ++DAD +TP
Sbjct: 220 LGYNALHYSKLSENAGIQSLLLSKI----SQDADLKTP 253
Score = 83.0 bits (196), Expect = 3e-15
Identities = 58/199 (29%), Positives = 89/199 (44%), Gaps = 4/199 (2%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
++ H A E ++ ++ G + LH+AA C + LL +
Sbjct: 57 KTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAE 116
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
+ GK TALH AA G + ++L +H + I+ + G PL LA E+ L+
Sbjct: 117 SVDSSGK-TALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 175
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
D ADV +++ GRT L A G+ + L+ GAD N D+ GY LH + L+E
Sbjct: 176 DHGADVNSRNKSGRTALMLACEIGSS--NAVEALIKKGADLNLVDSLGYNALHYSKLSEN 233
Query: 366 SACVLLLLD-YGGDVTLRT 383
+ LLL D L+T
Sbjct: 234 AGIQSLLLSKISQDADLKT 252
Score = 69.7 bits (163), Expect = 3e-11
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 12/218 (5%)
Query: 56 SEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDD 115
+E+++ L+G T ++EG +TA A G L ++ GVD D
Sbjct: 35 AEKVASLLGKKGASAT---KHDSEG----KTAFHLAAAKGHVECLRVMITHGVDVTAQDT 87
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL+ EC++ LL + DSS + T LH AA+ L V++L H
Sbjct: 88 TGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGK---TALHYAAAQGCLQAVQILCEH 144
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
+ +N L PL AV + E+ LL+ GA ++ T L +A +GS++
Sbjct: 145 KSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAV 204
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ L+ GAD+ G ALH + +A LLL
Sbjct: 205 EALIKKGADLNLVDSLG-YNALHYSKLSENAGIQSLLL 241
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Query: 259 AAEDGHAE-CARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
A E+G AE A LL GA + G+T HLA +E + +++ DV A+D
Sbjct: 29 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 88
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A C R LL + + D+ G T LH AA V +L ++
Sbjct: 89 GHSALHLAAKNSHHEC--IRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 146
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYL 405
+ L+ G L V+ I +L
Sbjct: 147 PINLKDLDGNIPLLLAVQNGHSEICHFL 174
>AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containing
protein ASB-2 protein.
Length = 544
Score = 96.3 bits (229), Expect = 4e-19
Identities = 82/276 (29%), Positives = 124/276 (44%), Gaps = 10/276 (3%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLI-AHGADVNAG-LSD 185
G EE +K ++ G N + + E PLH AA + C+KVL A+ ++ L +
Sbjct: 27 GDEEALKTMIKEGK--NLAEPNKEGWL-PLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQE 83
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
+ ++ A + + LL+AGA PD ETPL+ A +A K+L+ AD
Sbjct: 84 ETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTN 143
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
G TALH + E ++L+ GA ++ N G TPL +A + LE + L
Sbjct: 144 HRCNRGW-TALHESVSRNDLEVMQILVSGGAKVESKNAYG-TPLFVAAQSGQLEALRFLA 201
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
AD+ + +D + L+ A ++ LLS GAD N + G PLHIA+
Sbjct: 202 KYGADINTQASDNASALYEACKNEHE--EVVEFLLSQGADANKTNKDGLLPLHIASKKGN 259
Query: 366 SACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPDVI 401
V +LL +R GVS L R D +
Sbjct: 260 YRIVQMLLPVTSRTRIR-RSGVSPLHLAAERNHDEV 294
Score = 88.6 bits (210), Expect = 7e-17
Identities = 63/208 (30%), Positives = 97/208 (46%), Gaps = 3/208 (1%)
Query: 183 LSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
L+ PL A+ E +K +++ G P PLH AA G C K+L A
Sbjct: 14 LAPADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYP 73
Query: 243 DVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVE 302
+ TA++LA GH +C LL GA D N +TPL+ A ++ E V+
Sbjct: 74 GTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVK 133
Query: 303 MLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAAL 362
+LV AD + G T LH ++ R ++ ++L+S GA + + +G TPL +AA
Sbjct: 134 ILVQHNADTNHRCNRGWTALHESVSR--NDLEVMQILVSGGAKVESKNAYG-TPLFVAAQ 190
Query: 363 NEFSACVLLLLDYGGDVTLRTNGGVSAL 390
+ + L YG D+ + + SAL
Sbjct: 191 SGQLEALRFLAKYGADINTQASDNASAL 218
Score = 87.4 bits (207), Expect = 2e-16
Identities = 82/286 (28%), Positives = 126/286 (44%), Gaps = 8/286 (2%)
Query: 95 GKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKA 154
G L ++K G + E + G LH + G C+K+L A+P T D T +
Sbjct: 27 GDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVL--QRAYPGTIDQRTLQEE 84
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDT 213
T ++ A L C+ L+ GA+ + R +PL+ A E VK L++ A +
Sbjct: 85 TAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNH 144
Query: 214 PQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD 273
T LH + S ++L++ GA V + G T L +AA+ G E R L
Sbjct: 145 RCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG--TPLFVAAQSGQLEALRFLAK 202
Query: 274 HGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARAC 333
+GA I+ + L+ A + EVVE L+ + AD + DG PLH A +G
Sbjct: 203 YGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYR- 261
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDV 379
I ++LL + + G +PLH+AA + LL DV
Sbjct: 262 -IVQMLLPVTSRTRIRRS-GVSPLHLAAERNHDEVLEALLSARFDV 305
Score = 83.8 bits (198), Expect = 2e-15
Identities = 84/301 (27%), Positives = 132/301 (43%), Gaps = 15/301 (4%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
TA+ A G L LL+ G +PD + + T L+ +C + E VK+L+ H A N
Sbjct: 85 TAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTN- 143
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
T LH + S L +++L++ GA V + + +PL A S E ++ L
Sbjct: 144 --HRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGTPLFVAAQSGQLEALRFLA 201
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ GA +T + L+ A + LL+ GAD G LH+A++ G+
Sbjct: 202 KYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDG-LLPLHIASKKGNY 260
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLH-- 323
++LL + G +PLHLA EV+E L+ DV A R L+
Sbjct: 261 RIVQMLLPVTSRTRIRR-SGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYED 319
Query: 324 ---GAIVRGARACDI--ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
A+ ++ LLL GADPN +PL +A + + LLLD+G +
Sbjct: 320 RRSSALYFAVVNNNVYATELLLQHGADPN---RDVISPLLVAIRHGCLRTMQLLLDHGAN 376
Query: 379 V 379
+
Sbjct: 377 I 377
Score = 65.7 bits (153), Expect = 6e-10
Identities = 68/255 (26%), Positives = 110/255 (43%), Gaps = 16/255 (6%)
Query: 100 LFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHC 159
+ ++L G E +A T L ++ G E ++ L +GA NT S A+ L+
Sbjct: 164 VMQILVSGGAKVESKNAYGTPLFVAAQSGQLEALRFLAKYGADINTQASDN---ASALYE 220
Query: 160 AASAKSLACVKVLIAHGADVNAGLSDRS-PLHYAVLSDAPEVVKELLEAGACPDTPQVFT 218
A + V+ L++ GAD N D PLH A +V+ LL + +
Sbjct: 221 ACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIVQMLLPVTSRTRIRRSGV 280
Query: 219 ETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKA--------TALHLAAEDGHAECARL 270
+PLH+AA + LL+A DV + P +A +AL+ A + + L
Sbjct: 281 -SPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATEL 339
Query: 271 LLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
LL HGA PN +PL +A L +++L+D A++ A A T I+
Sbjct: 340 LLQHGAD---PNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAM 396
Query: 331 RACDIARLLLSAGAD 345
+ + + L+ G D
Sbjct: 397 KCLSLLKFLMDLGCD 411
Score = 52.8 bits (121), Expect = 4e-06
Identities = 43/147 (29%), Positives = 68/147 (46%), Gaps = 7/147 (4%)
Query: 253 ATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATL---AQSLEVVEMLVDRCA 309
A L A +DG E + ++ G ++ PN G PLH A L+V++
Sbjct: 17 ADPLIKAIKDGDEEALKTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTI 76
Query: 310 DVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACV 369
D R + T ++ A RG C ++ LL AGA+P+ ++ TPL+ A + + V
Sbjct: 77 DQRTLQEE--TAVYLATCRGHLDCLLS--LLQAGAEPDISNKSRETPLYKACERKNAEAV 132
Query: 370 LLLLDYGGDVTLRTNGGVSALSFIVRR 396
+L+ + D R N G +AL V R
Sbjct: 133 KILVQHNADTNHRCNRGWTALHESVSR 159
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 96.3 bits (229), Expect = 4e-19
Identities = 65/197 (32%), Positives = 96/197 (48%), Gaps = 3/197 (1%)
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
DA +V L + GA +T H+AA+ G C ++++ G DV A G +A
Sbjct: 31 DAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGH-SA 89
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
LHLAA++ H EC R LL + + G+T LH A L+ V++L + + + KD
Sbjct: 90 LHLAAKNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKD 149
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG PL A+ G +I LL GAD N+ + G T L +A S V L+
Sbjct: 150 LDGNIPLLLAVQNG--HSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 207
Query: 376 GGDVTLRTNGGVSALSF 392
G D+ L + G +AL +
Sbjct: 208 GADLNLVDSLGYNALHY 224
Score = 91.5 bits (217), Expect = 1e-17
Identities = 62/196 (31%), Positives = 94/196 (47%), Gaps = 5/196 (2%)
Query: 129 SEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRS 187
+E+ LL GA DS +T H AA+ + C++V+I HG DV A + S
Sbjct: 32 AEKVASLLGKKGASATKHDSEGKTA---FHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 88
Query: 188 PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAA 247
LH A + E ++ LL++ ++ +T LH AA+ G ++L + +
Sbjct: 89 ALHLAAKNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 148
Query: 248 MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDR 307
G L LA ++GH+E LLDHGA ++ N G+T L LA S VE L+ +
Sbjct: 149 DLDGNIPLL-LAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 207
Query: 308 CADVRAKDADGRTPLH 323
AD+ D+ G LH
Sbjct: 208 GADLNLVDSLGYNALH 223
Score = 83.8 bits (198), Expect = 2e-15
Identities = 59/218 (27%), Positives = 101/218 (46%), Gaps = 9/218 (4%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K G + D G+T HL+ G EC+++++ HG D+ T + LH AA
Sbjct: 41 KKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDT---TGHSALHLAAKNS 97
Query: 165 SLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
C++ L+ + S ++ LHYA + V+ L E + + + PL
Sbjct: 98 HHECIRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLL 157
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
+A G + LL+ GADV + G+ TAL LA E G + L+ GA ++ +
Sbjct: 158 LAVQNGHSEICHFLLDHGADVNSRNKSGR-TALMLACEIGSSNAVEALIKKGADLNLVDS 216
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
G LH + L+++ + +L+ + ++DAD +TP
Sbjct: 217 LGYNALHYSKLSENAGIQSLLLSKI----SQDADLKTP 250
Score = 83.0 bits (196), Expect = 3e-15
Identities = 58/199 (29%), Positives = 89/199 (44%), Gaps = 4/199 (2%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
++ H A E ++ ++ G + LH+AA C + LL +
Sbjct: 54 KTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRRLLQSKCPAE 113
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
+ GK TALH AA G + ++L +H + I+ + G PL LA E+ L+
Sbjct: 114 SVDSSGK-TALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 172
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
D ADV +++ GRT L A G+ + L+ GAD N D+ GY LH + L+E
Sbjct: 173 DHGADVNSRNKSGRTALMLACEIGSS--NAVEALIKKGADLNLVDSLGYNALHYSKLSEN 230
Query: 366 SACVLLLLD-YGGDVTLRT 383
+ LLL D L+T
Sbjct: 231 AGIQSLLLSKISQDADLKT 249
Score = 69.7 bits (163), Expect = 3e-11
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 12/218 (5%)
Query: 56 SEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDD 115
+E+++ L+G T ++EG +TA A G L ++ GVD D
Sbjct: 32 AEKVASLLGKKGASAT---KHDSEG----KTAFHLAAAKGHVECLRVMITHGVDVTAQDT 84
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL+ EC++ LL + DSS + T LH AA+ L V++L H
Sbjct: 85 TGHSALHLAAKNSHHECIRRLLQSKCPAESVDSSGK---TALHYAAAQGCLQAVQILCEH 141
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
+ +N L PL AV + E+ LL+ GA ++ T L +A +GS++
Sbjct: 142 KSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAV 201
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ L+ GAD+ G ALH + +A LLL
Sbjct: 202 EALIKKGADLNLVDSLG-YNALHYSKLSENAGIQSLLL 238
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Query: 259 AAEDGHAE-CARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
A E+G AE A LL GA + G+T HLA +E + +++ DV A+D
Sbjct: 26 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 85
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A C R LL + + D+ G T LH AA V +L ++
Sbjct: 86 GHSALHLAAKNSHHEC--IRRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 143
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYL 405
+ L+ G L V+ I +L
Sbjct: 144 PINLKDLDGNIPLLLAVQNGHSEICHFL 171
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 96.3 bits (229), Expect = 4e-19
Identities = 65/197 (32%), Positives = 96/197 (48%), Gaps = 3/197 (1%)
Query: 196 DAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATA 255
DA +V L + GA +T H+AA+ G C ++++ G DV A G +A
Sbjct: 40 DAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGH-SA 98
Query: 256 LHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKD 315
LHLAA++ H EC R LL + + G+T LH A L+ V++L + + + KD
Sbjct: 99 LHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKD 158
Query: 316 ADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDY 375
DG PL A+ G +I LL GAD N+ + G T L +A S V L+
Sbjct: 159 LDGNIPLLLAVQNG--HSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 216
Query: 376 GGDVTLRTNGGVSALSF 392
G D+ L + G +AL +
Sbjct: 217 GADLNLVDSLGYNALHY 233
Score = 91.9 bits (218), Expect = 8e-18
Identities = 62/196 (31%), Positives = 95/196 (48%), Gaps = 5/196 (2%)
Query: 129 SEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRS 187
+E+ LL GA DS +T H AA+ + C++V+I HG DV A + S
Sbjct: 41 AEKVASLLGKKGASATKHDSEGKTA---FHLAAAKGHVECLRVMITHGVDVTAQDTTGHS 97
Query: 188 PLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAA 247
LH A + E +++LL++ ++ +T LH AA+ G ++L + +
Sbjct: 98 ALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLK 157
Query: 248 MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDR 307
G L LA ++GH+E LLDHGA ++ N G+T L LA S VE L+ +
Sbjct: 158 DLDGNIPLL-LAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEALIKK 216
Query: 308 CADVRAKDADGRTPLH 323
AD+ D+ G LH
Sbjct: 217 GADLNLVDSLGYNALH 232
Score = 84.2 bits (199), Expect = 2e-15
Identities = 59/218 (27%), Positives = 101/218 (46%), Gaps = 9/218 (4%)
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K G + D G+T HL+ G EC+++++ HG D+ T + LH AA
Sbjct: 50 KKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDT---TGHSALHLAAKNS 106
Query: 165 SLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
C++ L+ + S ++ LHYA + V+ L E + + + PL
Sbjct: 107 HHECIRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLL 166
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNF 283
+A G + LL+ GADV + G+ TAL LA E G + L+ GA ++ +
Sbjct: 167 LAVQNGHSEICHFLLDHGADVNSRNKSGR-TALMLACEIGSSNAVEALIKKGADLNLVDS 225
Query: 284 RGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
G LH + L+++ + +L+ + ++DAD +TP
Sbjct: 226 LGYNALHYSKLSENAGIQSLLLSKI----SQDADLKTP 259
Score = 83.0 bits (196), Expect = 3e-15
Identities = 58/199 (29%), Positives = 89/199 (44%), Gaps = 4/199 (2%)
Query: 186 RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVR 245
++ H A E ++ ++ G + LH+AA C + LL +
Sbjct: 63 KTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAE 122
Query: 246 AAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLV 305
+ GK TALH AA G + ++L +H + I+ + G PL LA E+ L+
Sbjct: 123 SVDSSGK-TALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLL 181
Query: 306 DRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
D ADV +++ GRT L A G+ + L+ GAD N D+ GY LH + L+E
Sbjct: 182 DHGADVNSRNKSGRTALMLACEIGSS--NAVEALIKKGADLNLVDSLGYNALHYSKLSEN 239
Query: 366 SACVLLLLD-YGGDVTLRT 383
+ LLL D L+T
Sbjct: 240 AGIQSLLLSKISQDADLKT 258
Score = 69.7 bits (163), Expect = 3e-11
Identities = 63/218 (28%), Positives = 98/218 (44%), Gaps = 12/218 (5%)
Query: 56 SEEISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLLKMGVDPDELDD 115
+E+++ L+G T ++EG +TA A G L ++ GVD D
Sbjct: 41 AEKVASLLGKKGASAT---KHDSEG----KTAFHLAAAKGHVECLRVMITHGVDVTAQDT 93
Query: 116 AGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAH 175
G + LHL+ EC++ LL + DSS + T LH AA+ L V++L H
Sbjct: 94 TGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGK---TALHYAAAQGCLQAVQILCEH 150
Query: 176 GADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCT 234
+ +N L PL AV + E+ LL+ GA ++ T L +A +GS++
Sbjct: 151 KSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAV 210
Query: 235 KLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLL 272
+ L+ GAD+ G ALH + +A LLL
Sbjct: 211 EALIKKGADLNLVDSLG-YNALHYSKLSENAGIQSLLL 247
Score = 54.8 bits (126), Expect = 1e-06
Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 3/148 (2%)
Query: 259 AAEDGHAE-CARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDAD 317
A E+G AE A LL GA + G+T HLA +E + +++ DV A+D
Sbjct: 35 AVENGDAEKVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTT 94
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGG 377
G + LH A C R LL + + D+ G T LH AA V +L ++
Sbjct: 95 GHSALHLAAKNSHHEC--IRKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 152
Query: 378 DVTLRTNGGVSALSFIVRRVPDVIPRYL 405
+ L+ G L V+ I +L
Sbjct: 153 PINLKDLDGNIPLLLAVQNGHSEICHFL 180
>BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protein 2
protein.
Length = 1202
Score = 95.9 bits (228), Expect = 5e-19
Identities = 81/215 (37%), Positives = 108/215 (50%), Gaps = 12/215 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
S LH+A L + E++ LLEA A D PLH AA G +LLL A A V A
Sbjct: 51 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNA 110
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
A G+ LHLAA+ GH E + +LL H ++ N +TPL LA L+V ++L++
Sbjct: 111 ASLDGQ-IPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLN 169
Query: 307 R--CA---DVRAK---DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
C + AK D + TPLH A G R ++ R LL AG + N G T LH
Sbjct: 170 SHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHR--EVIRQLLRAGIEINRQTKTG-TALH 226
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFI 393
AAL + V LLL+ G DV +R +AL +
Sbjct: 227 EAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIV 261
Score = 89.4 bits (212), Expect = 4e-17
Identities = 80/235 (34%), Positives = 109/235 (46%), Gaps = 14/235 (5%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
K+ LL ++ V+ + D G + LH + L GS E + LLL+ A T D
Sbjct: 30 KTKLLGSTKRLNVNYQDAD--GFSALHHAALGGSLELIALLLEAQA---TVDIKDSNGMR 84
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTP 214
PLH AA L V++L+ A VNA L + PLH A EV + LL+ + P
Sbjct: 85 PLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLV 144
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG-------PGKATALHLAAEDGHAEC 267
+TPL +A G +LLLN+ V G P T LHLAA++GH E
Sbjct: 145 NKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREV 204
Query: 268 ARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
R LL G I+ G T LH A L EVV +L++ DV ++ +T L
Sbjct: 205 IRQLLRAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTAL 258
Score = 64.5 bits (150), Expect = 1e-09
Identities = 73/260 (28%), Positives = 109/260 (41%), Gaps = 19/260 (7%)
Query: 94 LGKSI-LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTET 152
LG S+ L+ LL+ D D G LH + G E V+LLL A N +++
Sbjct: 58 LGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVN---AASLD 114
Query: 153 KATPLHCAASAKSLACVKVLIAHGAD-VNAGLSDRSPLHYAVLSDAPEVVKELLEAGAC- 210
PLH AA ++L+ H ++ + ++PL A +V + LL + C
Sbjct: 115 GQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCV 174
Query: 211 -------PDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
D TPLH+AA G + LL AG ++ G TALH AA G
Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG--TALHEAALYG 232
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHL----ATLAQSLEVVEMLVDRCADVRAKDADGR 319
E RLLL+ G ++ N QT L + T S E+ ++L + ++ +
Sbjct: 233 KTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDF 292
Query: 320 TPLHGAIVRGARACDIARLL 339
LH RA D+ +L
Sbjct: 293 WNLHDPTALNVRAGDVITVL 312
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++++ + G + LH A L SLE++ +L++ A V KD++G PLH A +G +
Sbjct: 41 NVNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQG--RLEPV 98
Query: 337 RLLLSAGADPNAADNFGYTPLHIAA 361
RLLL A A NAA G PLH+AA
Sbjct: 99 RLLLRASAAVNAASLDGQIPLHLAA 123
Score = 52.4 bits (120), Expect = 6e-06
Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 15/165 (9%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
+A W G+ + LL+ + G+ LHL+ G E ++LL H ++P
Sbjct: 88 YAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCL---V 144
Query: 150 TETKATPLHCAAS----------AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPE 199
+ K TPL A S CV +L D + +PLH A + E
Sbjct: 145 NKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKD-PCDPNYTTPLHLAAKNGHRE 203
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV 244
V+++LL AG Q T T LH AA G +LLL G DV
Sbjct: 204 VIRQLLRAG-IEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDV 247
>BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 29
protein.
Length = 301
Score = 95.9 bits (228), Expect = 5e-19
Identities = 86/256 (33%), Positives = 120/256 (46%), Gaps = 7/256 (2%)
Query: 128 GSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGL-SDR 186
G+ +KLLL+ G S T T L AA A + CV+ L+ GAD+N S
Sbjct: 23 GNLALLKLLLNSGRVDVDCRDSHGT--TLLMVAAYAGHIDCVRELVLQGADINLQRESGT 80
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
+ L +A +VV+ L GA + T L A+ G + LL GA++
Sbjct: 81 TALFFAAQQGHNDVVRFLFGFGASTEFRTKDEGTALLAASQYGHMQVVETLLKHGANIHD 140
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
+ G ATAL LAA+ G+ + RLLL GA ++ P G PL +A+ EVV +++
Sbjct: 141 QLYDG-ATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLL 199
Query: 307 RCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFS 366
R AD A DG T L A +G D+ + LL N G + LH A L+
Sbjct: 200 RGADRDAARNDGTTALLKAANKGYN--DVIKELLKFSPTLGILKN-GTSALHAAVLSGNI 256
Query: 367 ACVLLLLDYGGDVTLR 382
V LLL+ G D +LR
Sbjct: 257 KTVALLLEAGADPSLR 272
Score = 81.0 bits (191), Expect = 1e-14
Identities = 85/278 (30%), Positives = 118/278 (42%), Gaps = 9/278 (3%)
Query: 84 LRTAILWACWLGKSILLFKLLKMG-VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAH 142
L A WA G LL LL G VD D D G T L ++ G +CV+ L+ GA
Sbjct: 12 LANAAFWAARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGAD 71
Query: 143 PNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDR-SPLHYAVLSDAPEVV 201
N E+ T L AA V+ L GA D + L A +VV
Sbjct: 72 INL---QRESGTTALFFAAQQGHNDVVRFLFGFGASTEFRTKDEGTALLAASQYGHMQVV 128
Query: 202 KELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAE 261
+ LL+ GA T L +AA G +LLL +GA V G A L +A++
Sbjct: 129 ETLLKHGANIHDQLYDGATALFLAAQGGYLDVIRLLLASGAKVNQPRQDGTAP-LWIASQ 187
Query: 262 DGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTP 321
GH+E R++L GA D G T L A +V++ L+ + + +G +
Sbjct: 188 MGHSEVVRVMLLRGADRDAARNDGTTALLKAANKGYNDVIKELL-KFSPTLGILKNGTSA 246
Query: 322 LHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHI 359
LH A++ G LLL AGADP+ + P +
Sbjct: 247 LHAAVLSGN--IKTVALLLEAGADPSLRNKANELPAEL 282
Score = 77.4 bits (182), Expect = 2e-13
Identities = 67/216 (31%), Positives = 97/216 (44%), Gaps = 4/216 (1%)
Query: 200 VVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHL 258
++K LL +G D T L VAA G C + L+ GAD+ G TAL
Sbjct: 27 LLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQGADINLQRESG-TTALFF 85
Query: 259 AAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADG 318
AA+ GH + R L GA ++ T L A+ ++VVE L+ A++ + DG
Sbjct: 86 AAQQGHNDVVRFLFGFGASTEFRTKDEGTALLAASQYGHMQVVETLLKHGANIHDQLYDG 145
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
T L A G D+ RLLL++GA N G PL IA+ S V ++L G D
Sbjct: 146 ATALFLAAQGGY--LDVIRLLLASGAKVNQPRQDGTAPLWIASQMGHSEVVRVMLLRGAD 203
Query: 379 VTLRTNGGVSALSFIVRRVPDVIPRYLCKFDDAVHV 414
N G +AL + + + + L KF + +
Sbjct: 204 RDAARNDGTTALLKAANKGYNDVIKELLKFSPTLGI 239
Score = 43.2 bits (97), Expect = 0.003
Identities = 31/92 (33%), Positives = 48/92 (52%), Gaps = 3/92 (3%)
Query: 320 TPLHGAIVRGARACDIA--RLLLSAG-ADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
TPL A AR ++A +LLL++G D + D+ G T L +AA CV L+ G
Sbjct: 10 TPLANAAFWAARRGNLALLKLLLNSGRVDVDCRDSHGTTLLMVAAYAGHIDCVRELVLQG 69
Query: 377 GDVTLRTNGGVSALSFIVRRVPDVIPRYLCKF 408
D+ L+ G +AL F ++ + + R+L F
Sbjct: 70 ADINLQRESGTTALFFAAQQGHNDVVRFLFGF 101
>BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III and
ankyrin repeat domains 1 protein.
Length = 345
Score = 95.9 bits (228), Expect = 5e-19
Identities = 71/205 (34%), Positives = 97/205 (47%), Gaps = 6/205 (2%)
Query: 189 LHYAVLSDAPEVVKELLEAGACP-DTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAA 247
LH AV + +++ +L+ G D P F T L VAA G K+L++ G DV
Sbjct: 114 LHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLK 173
Query: 248 MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDR 307
G GK +L LA GH + + L HGA + G T LH A V+E ++
Sbjct: 174 NGSGK-DSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKD 232
Query: 308 CADVRAKDA-DGRTPL-HGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEF 365
+V D G TPL + V G + +A LL+ AGA+ N D G TPL +A LN
Sbjct: 233 GCEVDVVDTGSGWTPLMRVSAVSGNQR--VASLLIDAGANVNVKDRNGKTPLMVAVLNNH 290
Query: 366 SACVLLLLDYGGDVTLRTNGGVSAL 390
V LLLD G D +++ G L
Sbjct: 291 EELVQLLLDKGADASVKNEFGKGVL 315
Score = 76.2 bits (179), Expect = 4e-13
Identities = 63/209 (30%), Positives = 98/209 (46%), Gaps = 4/209 (1%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
LH + V E+ + +L G D + T L AA VK+L+++G DVN
Sbjct: 114 LHRAVSVNDEDLLVRILQGGRVKV--DVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVN 171
Query: 181 A-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLN 239
S + L A + +VVK L GA + T LH AA G S + ++
Sbjct: 172 LKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIK 231
Query: 240 AGADVRAA-MGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSL 298
G +V G G + ++A G+ A LL+D GA+++ + G+TPL +A L
Sbjct: 232 DGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHE 291
Query: 299 EVVEMLVDRCADVRAKDADGRTPLHGAIV 327
E+V++L+D+ AD K+ G+ L A V
Sbjct: 292 ELVQLLLDKGADASVKNEFGKGVLEMARV 320
Score = 68.5 bits (160), Expect = 8e-11
Identities = 69/220 (31%), Positives = 101/220 (45%), Gaps = 8/220 (3%)
Query: 99 LLFKLLKMG-VDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPL 157
LL ++L+ G V D + G T L ++ G VK+L+ +G N + S + L
Sbjct: 125 LLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDS---L 181
Query: 158 HCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQV 216
A A L VK L HGA A L + LH+A V++ +++ G D
Sbjct: 182 MLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDT 241
Query: 217 FTE-TPL-HVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH 274
+ TPL V+A G+ LL++AGA+V GK T L +A + H E +LLLD
Sbjct: 242 GSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGK-TPLMVAVLNNHEELVQLLLDK 300
Query: 275 GAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
GA N G+ L +A + VV +L +R R K
Sbjct: 301 GADASVKNEFGKGVLEMARVFDRQSVVSLLEERKKKQRPK 340
Score = 68.5 bits (160), Expect = 8e-11
Identities = 52/175 (29%), Positives = 84/175 (48%), Gaps = 5/175 (2%)
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLA 259
+VK L+ G + + L +A G K L GA +A G TALH A
Sbjct: 159 LVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQAR-DLGGCTALHWA 217
Query: 260 AEDGHAECARLLLDHGAHIDWPNF-RGQTPL-HLATLAQSLEVVEMLVDRCADVRAKDAD 317
A+ GH ++ G +D + G TPL ++ ++ + V +L+D A+V KD +
Sbjct: 218 ADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRN 277
Query: 318 GRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
G+TPL A++ ++ +LLL GAD + + FG L +A + + + V LL
Sbjct: 278 GKTPLMVAVLNNHE--ELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLL 330
Score = 58.4 bits (135), Expect = 9e-08
Identities = 51/175 (29%), Positives = 80/175 (45%), Gaps = 9/175 (5%)
Query: 82 FGLRTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGA 141
FG TA++ A G + L+ L+ G D + + +G+ L L+C G + VK L HGA
Sbjct: 143 FGF-TALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGA 201
Query: 142 HPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGAD---VNAGLSDRSPLHYAVLSDAP 198
+W + T LH AA + ++ +I G + V+ G + + +S
Sbjct: 202 ---SWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQ 258
Query: 199 EVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGAD--VRAAMGPG 251
V L++AGA + +TPL VA +LLL+ GAD V+ G G
Sbjct: 259 RVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKG 313
>AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protein 2
protein.
Length = 1202
Score = 95.9 bits (228), Expect = 5e-19
Identities = 81/215 (37%), Positives = 108/215 (50%), Gaps = 12/215 (5%)
Query: 187 SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRA 246
S LH+A L + E++ LLEA A D PLH AA G +LLL A A V A
Sbjct: 51 SALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNA 110
Query: 247 AMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVD 306
A G+ LHLAA+ GH E + +LL H ++ N +TPL LA L+V ++L++
Sbjct: 111 ASLDGQ-IPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLN 169
Query: 307 R--CA---DVRAK---DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLH 358
C + AK D + TPLH A G R ++ R LL AG + N G T LH
Sbjct: 170 SHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHR--EVIRQLLRAGIEINRQTKTG-TALH 226
Query: 359 IAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFI 393
AAL + V LLL+ G DV +R +AL +
Sbjct: 227 EAALYGKTEVVRLLLEGGVDVNIRNTYNQTALDIV 261
Score = 89.4 bits (212), Expect = 4e-17
Identities = 80/235 (34%), Positives = 109/235 (46%), Gaps = 14/235 (5%)
Query: 96 KSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKAT 155
K+ LL ++ V+ + D G + LH + L GS E + LLL+ A T D
Sbjct: 30 KTKLLGSTKRLNVNYQDAD--GFSALHHAALGGSLELIALLLEAQA---TVDIKDSNGMR 84
Query: 156 PLHCAASAKSLACVKVLIAHGADVNAG-LSDRSPLHYAVLSDAPEVVKELLEAGACPDTP 214
PLH AA L V++L+ A VNA L + PLH A EV + LL+ + P
Sbjct: 85 PLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCLV 144
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMG-------PGKATALHLAAEDGHAEC 267
+TPL +A G +LLLN+ V G P T LHLAA++GH E
Sbjct: 145 NKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKDPCDPNYTTPLHLAAKNGHREV 204
Query: 268 ARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPL 322
R LL G I+ G T LH A L EVV +L++ DV ++ +T L
Sbjct: 205 IRQLLRAGIEINRQTKTG-TALHEAALYGKTEVVRLLLEGGVDVNIRNTYNQTAL 258
Score = 64.5 bits (150), Expect = 1e-09
Identities = 73/260 (28%), Positives = 109/260 (41%), Gaps = 19/260 (7%)
Query: 94 LGKSI-LLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTET 152
LG S+ L+ LL+ D D G LH + G E V+LLL A N +++
Sbjct: 58 LGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVN---AASLD 114
Query: 153 KATPLHCAASAKSLACVKVLIAHGAD-VNAGLSDRSPLHYAVLSDAPEVVKELLEAGAC- 210
PLH AA ++L+ H ++ + ++PL A +V + LL + C
Sbjct: 115 GQIPLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCV 174
Query: 211 -------PDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
D TPLH+AA G + LL AG ++ G TALH AA G
Sbjct: 175 ALLEGEAKDPCDPNYTTPLHLAAKNGHREVIRQLLRAGIEINRQTKTG--TALHEAALYG 232
Query: 264 HAECARLLLDHGAHIDWPNFRGQTPLHL----ATLAQSLEVVEMLVDRCADVRAKDADGR 319
E RLLL+ G ++ N QT L + T S E+ ++L + ++ +
Sbjct: 233 KTEVVRLLLEGGVDVNIRNTYNQTALDIVNQFTTSQASREIKQLLREASGILKVRALKDF 292
Query: 320 TPLHGAIVRGARACDIARLL 339
LH RA D+ +L
Sbjct: 293 WNLHDPTALNVRAGDVITVL 312
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/85 (40%), Positives = 50/85 (58%), Gaps = 2/85 (2%)
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
++++ + G + LH A L SLE++ +L++ A V KD++G PLH A +G +
Sbjct: 41 NVNYQDADGFSALHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQG--RLEPV 98
Query: 337 RLLLSAGADPNAADNFGYTPLHIAA 361
RLLL A A NAA G PLH+AA
Sbjct: 99 RLLLRASAAVNAASLDGQIPLHLAA 123
Score = 52.4 bits (120), Expect = 6e-06
Identities = 49/165 (29%), Positives = 69/165 (41%), Gaps = 15/165 (9%)
Query: 90 WACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSS 149
+A W G+ + LL+ + G+ LHL+ G E ++LL H ++P
Sbjct: 88 YAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQHQSNPCL---V 144
Query: 150 TETKATPLHCAAS----------AKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPE 199
+ K TPL A S CV +L D + +PLH A + E
Sbjct: 145 NKAKKTPLDLACEFGRLKVAQLLLNSHLCVALLEGEAKD-PCDPNYTTPLHLAAKNGHRE 203
Query: 200 VVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADV 244
V+++LL AG Q T T LH AA G +LLL G DV
Sbjct: 204 VIRQLLRAG-IEINRQTKTGTALHEAALYGKTEVVRLLLEGGVDV 247
>BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein.
Length = 399
Score = 95.1 bits (226), Expect = 8e-19
Identities = 77/265 (29%), Positives = 124/265 (46%), Gaps = 9/265 (3%)
Query: 121 LHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN 180
L LS G +++L++ GA + ++ T LHCAA + + ++ DV
Sbjct: 4 LLLSAWFGHLRILQILVNSGAKIHC---ESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA 60
Query: 181 AGLSD---RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
D R+ H A + + L+ +G + T LH+AA G + + L
Sbjct: 61 LDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRL 120
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
++ G D+ G TALH AA H +C +LLL G+ ++ + + LH A L+ S
Sbjct: 121 VDIGLDLEEQNAEG-LTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGS 179
Query: 298 LEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPL 357
+V +L+ D G +PLH A+ A + RLL+++ +D NA DN TPL
Sbjct: 180 EDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPA--LVRLLINSDSDVNAVDNRQQTPL 237
Query: 358 HIAALNEFSACVLLLLDYGGDVTLR 382
H+AA + + +LL G D+ LR
Sbjct: 238 HLAAEHAWQDIADMLLIAGVDLNLR 262
Score = 90.2 bits (214), Expect = 2e-17
Identities = 76/265 (28%), Positives = 115/265 (43%), Gaps = 5/265 (1%)
Query: 87 AILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTW 146
A+L + W G +L L+ G G T LH + G + +++
Sbjct: 3 ALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMED-LEDVAL 61
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSD-RSPLHYAVLSDAPEVVKELL 205
D + T H AA L + L+ G D N + + LH A V++ L+
Sbjct: 62 DHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLV 121
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ G + T LH AA C +LLL AG+ V A + + LH AA G
Sbjct: 122 DIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNA-LTQKNLSCLHYAALSGSE 180
Query: 266 ECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGA 325
+ +R+L+ G + + +G +PLHLA +V +L++ +DV A D +TPLH A
Sbjct: 181 DVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLA 240
Query: 326 IVRGARACDIARLLLSAGADPNAAD 350
+ DIA +LL AG D N D
Sbjct: 241 AEHAWQ--DIADMLLIAGVDLNLRD 263
Score = 84.6 bits (200), Expect = 1e-15
Identities = 64/196 (32%), Positives = 95/196 (48%), Gaps = 5/196 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
RTA A G+ L L+ G D + D G T LHL+ G ++ L+D G
Sbjct: 69 RTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGL--- 125
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKE 203
+ T LH AA CV++L+ G+ VNA + S LHYA LS + +V +
Sbjct: 126 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 185
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDG 263
L+ AG C + +PLH+A + +LL+N+ +DV A+ + T LHLAAE
Sbjct: 186 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVN-AVDNRQQTPLHLAAEHA 244
Query: 264 HAECARLLLDHGAHID 279
+ A +LL G ++
Sbjct: 245 WQDIADMLLIAGVDLN 260
Score = 81.0 bits (191), Expect = 1e-14
Identities = 60/208 (28%), Positives = 96/208 (46%), Gaps = 5/208 (2%)
Query: 111 DELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVK 170
D +D GRT H + G + + L+ G N D T LH AA +A ++
Sbjct: 62 DHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTA---LHLAAGRGHMAVLQ 118
Query: 171 VLIAHGADVNAGLSDR-SPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLG 229
L+ G D+ ++ + LH A P+ V+ LL AG+ + + LH AA G
Sbjct: 119 RLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSG 178
Query: 230 SASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPL 289
S +++L++AG G A+ LHLA RLL++ + ++ + R QTPL
Sbjct: 179 SEDVSRVLIHAGGCANVVDHQG-ASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPL 237
Query: 290 HLATLAQSLEVVEMLVDRCADVRAKDAD 317
HLA ++ +ML+ D+ +D D
Sbjct: 238 HLAAEHAWQDIADMLLIAGVDLNLRDKD 265
Score = 76.2 bits (179), Expect = 4e-13
Identities = 63/227 (27%), Positives = 98/227 (43%), Gaps = 8/227 (3%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLD--HGAHID 279
L ++A G ++L+N+GA + G T LH AA+ GH +++ +D
Sbjct: 4 LLLSAWFGHLRILQILVNSGAKIHCESKDG-LTLLHCAAQKGHVPVLAFIMEDLEDVALD 62
Query: 280 WPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLL 339
+ G+T H A L+ ++ LV D KD +G T LH A RG A + + L
Sbjct: 63 HVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMA--VLQRL 120
Query: 340 LSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVPD 399
+ G D + G T LH AA CV LLL G V T +S L + +
Sbjct: 121 VDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSE 180
Query: 400 VIPRYLCKFDDAVHVSEHELGDVDCELTI--DFRPLVPCLTRGEAEL 444
+ R L +V +H+ G L + +F LV L ++++
Sbjct: 181 DVSRVLIHAGGCANVVDHQ-GASPLHLAVRHNFPALVRLLINSDSDV 226
Score = 72.9 bits (171), Expect = 4e-12
Identities = 60/199 (30%), Positives = 86/199 (43%), Gaps = 3/199 (1%)
Query: 220 TPLHVAASLGSASCTKLLLNAGADVRAA-MGPGKATALHLAAEDGHAECARLLLDHGAHI 278
T LH AA G ++ DV + TA H AAE G + L+ G
Sbjct: 35 TLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDH 94
Query: 279 DWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARL 338
+ + G T LHLA + V++ LVD D+ ++A+G T LH A G D +L
Sbjct: 95 NVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSA--AGGSHPDCVQL 152
Query: 339 LLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVRRVP 398
LL AG+ NA + LH AAL+ +L+ GG + + G S L VR
Sbjct: 153 LLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNF 212
Query: 399 DVIPRYLCKFDDAVHVSEH 417
+ R L D V+ ++
Sbjct: 213 PALVRLLINSDSDVNAVDN 231
>BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 909
Score = 94.7 bits (225), Expect = 1e-18
Identities = 69/200 (34%), Positives = 93/200 (46%), Gaps = 6/200 (3%)
Query: 178 DVNA--GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTK 235
DVN G RS LH A + E + LL+ GA P+ + TPLH+AA G C
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMS 115
Query: 236 LLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLA 295
LL ADV G TA+H A +G E L+ H + +D + GQT LH+A
Sbjct: 116 KLLEYSADVNICNNEG-LTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQN 174
Query: 296 QSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYT 355
V+ L+D AD+ + G TPL+ A G R D A++LL GA D G T
Sbjct: 175 GHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQR--DTAQILLLRGA-KYLPDKNGVT 231
Query: 356 PLHIAALNEFSACVLLLLDY 375
PL + + +L+ Y
Sbjct: 232 PLDLCVQGGYGETCEVLIQY 251
Score = 88.6 bits (210), Expect = 7e-17
Identities = 60/177 (33%), Positives = 86/177 (48%), Gaps = 4/177 (2%)
Query: 216 VFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHG 275
V+T P+ +A S S +LL N+ DV A G K + LH+AA G EC LLL G
Sbjct: 31 VYTLMPMVMADQHRSVS--ELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKG 88
Query: 276 AHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDI 335
A+ ++ + G TPLHLA + + L++ ADV + +G T +H V G ++
Sbjct: 89 ANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNG--RTEL 146
Query: 336 ARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSF 392
L+ +D + D G T LH+A N V LLD G D+ G + L F
Sbjct: 147 LHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYF 203
Score = 85.4 bits (202), Expect = 7e-16
Identities = 60/174 (34%), Positives = 85/174 (48%), Gaps = 4/174 (2%)
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
LH+AA+ GS C LLL GA+ G T LHLAA +G +C LL++ A ++
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISG-CTPLHLAARNGQKKCMSKLLEYSADVNIC 127
Query: 282 NFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLS 341
N G T +H + E++ LV +DV +DA G+T LH A G + + LL
Sbjct: 128 NNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTT--VQCLLD 185
Query: 342 AGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFIVR 395
+GAD N + G TPL+ A + +LL G L GV+ L V+
Sbjct: 186 SGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKY-LPDKNGVTPLDLCVQ 238
Score = 70.1 bits (164), Expect = 3e-11
Identities = 63/231 (27%), Positives = 104/231 (45%), Gaps = 15/231 (6%)
Query: 48 YTLRLLPYSEE---ISVLIGNGNYDETIQFASEAEGGFGLRTAILWACWLGKSILLFKLL 104
YTL + +++ +S L+ N +D F G R+ + A G L LL
Sbjct: 32 YTLMPMVMADQHRSVSELLSNSKFDVNYAF------GRVKRSLLHIAANCGSVECLVLLL 85
Query: 105 KMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAK 164
K G +P+ D +G T LHL+ G ++C+ LL++ A N ++ T +H A
Sbjct: 86 KKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNE---GLTAIHWLAVNG 142
Query: 165 SLACVKVLIAHGADVNA-GLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLH 223
+ L+ H +DV+ ++ LH A + V+ LL++GA + P V TPL+
Sbjct: 143 RTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLY 202
Query: 224 VAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH 274
A S G ++LL GA + T L L + G+ E +L+ +
Sbjct: 203 FACSHGQRDTAQILLLRGA--KYLPDKNGVTPLDLCVQGGYGETCEVLIQY 251
Score = 55.6 bits (128), Expect = 6e-07
Identities = 38/99 (38%), Positives = 53/99 (53%), Gaps = 3/99 (3%)
Query: 296 QSLEVVEMLVDRCADVR-AKDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGY 354
Q V E+L + DV A R+ LH A G+ C + LLL GA+PN D G
Sbjct: 42 QHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLV--LLLKKGANPNYQDISGC 99
Query: 355 TPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSALSFI 393
TPLH+AA N C+ LL+Y DV + N G++A+ ++
Sbjct: 100 TPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWL 138
>BX537857-1|CAD97864.1| 306|Homo sapiens hypothetical protein
protein.
Length = 306
Score = 93.9 bits (223), Expect = 2e-18
Identities = 67/187 (35%), Positives = 89/187 (47%), Gaps = 5/187 (2%)
Query: 118 RTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIAHGA 177
+T + +CL G C K LL++GAH N T ATPL A + S ACV VL+ GA
Sbjct: 82 KTLIAQACLGGHVACAKALLENGAHVN---GVTVHGATPLFNACCSGSAACVNVLLEFGA 138
Query: 178 DVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASCTKLL 237
+ SP+H AV E ++ LL D TPL+VA + C K L
Sbjct: 139 KAQLEVHLASPIHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTYQRVDCVKKL 198
Query: 238 LNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQS 297
L GA V G T LH AA + E LL D+GA++ N +G++ L LA S
Sbjct: 199 LELGASV--DHGQWLDTPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSALDLAAPKSS 256
Query: 298 LEVVEML 304
+E +L
Sbjct: 257 VEQALLL 263
Score = 78.2 bits (184), Expect = 1e-13
Identities = 68/218 (31%), Positives = 103/218 (47%), Gaps = 8/218 (3%)
Query: 56 SEEISVLIGNGNYDETIQFASEAEGGF-GLRTAILWACWLGKSILLFKLLKMGVDPDELD 114
+EEI I + D + + A+G L+T I AC G LL+ G + +
Sbjct: 52 AEEIYGGISDCWADRSPLHEAAAQGRLLALKTLIAQACLGGHVACAKALLENGAHVNGVT 111
Query: 115 DAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAASAKSLACVKVLIA 174
G T L +C GS CV +LL+ GA A+P+H A C+++L+A
Sbjct: 112 VHGATPLFNACCSGSAACVNVLLEFGAKAQL----EVHLASPIHEAVKRGHRECMEILLA 167
Query: 175 HGADVNAGLSD-RSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETPLHVAASLGSASC 233
+ +++ + +PL+ A + VK+LLE GA D Q + +TPLH AA +
Sbjct: 168 NNVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQ-WLDTPLHAAARQSNVEV 226
Query: 234 TKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLL 271
LL + GA+++ GK +AL LAA E A LL
Sbjct: 227 IHLLTDYGANLKRRNAQGK-SALDLAAPKSSVEQALLL 263
Score = 67.7 bits (158), Expect = 1e-10
Identities = 70/219 (31%), Positives = 100/219 (45%), Gaps = 23/219 (10%)
Query: 155 TPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTP 214
+PLH AA+ L +K LIA A L K LLE GA +
Sbjct: 67 SPLHEAAAQGRLLALKTLIAQ----------------ACLGGHVACAKALLENGAHVNGV 110
Query: 215 QVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDH 274
V TPL A GSA+C +LL GA +A + A+ +H A + GH EC +LL +
Sbjct: 111 TVHGATPLFNACCSGSAACVNVLLEFGA--KAQLEVHLASPIHEAVKRGHRECMEILLAN 168
Query: 275 GAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADV-RAKDADGRTPLHGAIVRGARAC 333
+ID + TPL++A Q ++ V+ L++ A V + D TPLH A R +
Sbjct: 169 NVNIDHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLD--TPLHAA-ARQSNV- 224
Query: 334 DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLL 372
++ LL GA+ + G + L +AA LLL
Sbjct: 225 EVIHLLTDYGANLKRRNAQGKSALDLAAPKSSVEQALLL 263
Score = 59.7 bits (138), Expect = 4e-08
Identities = 40/126 (31%), Positives = 61/126 (48%), Gaps = 3/126 (2%)
Query: 254 TALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRA 313
T + A GH CA+ LL++GAH++ G TPL A + S V +L++ A +
Sbjct: 83 TLIAQACLGGHVACAKALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAKAQL 142
Query: 314 KDADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLL 373
+ +P+H A+ RG R C L + D + G TPL++A + CV LL
Sbjct: 143 -EVHLASPIHEAVKRGHRECMEILLANNVNID-HEVPQLG-TPLYVACTYQRVDCVKKLL 199
Query: 374 DYGGDV 379
+ G V
Sbjct: 200 ELGASV 205
Score = 57.6 bits (133), Expect = 2e-07
Identities = 51/162 (31%), Positives = 69/162 (42%), Gaps = 5/162 (3%)
Query: 229 GSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTP 288
G +C K LL GA V G AT L A G A C +LL+ GA +P
Sbjct: 92 GHVACAKALLENGAHVNGVTVHG-ATPLFNACCSGSAACVNVLLEFGAKAQL-EVHLASP 149
Query: 289 LHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIARLLLSAGADPNA 348
+H A E +E+L+ ++ + TPL+ A + D + LL GA +
Sbjct: 150 IHEAVKRGHRECMEILLANNVNIDHEVPQLGTPLYVACTY--QRVDCVKKLLELGASVDH 207
Query: 349 ADNFGYTPLHIAALNEFSACVLLLLDYGGDVTLRTNGGVSAL 390
TPLH AA + LL DYG ++ R G SAL
Sbjct: 208 GQWLD-TPLHAAARQSNVEVIHLLTDYGANLKRRNAQGKSAL 248
Score = 48.8 bits (111), Expect = 7e-05
Identities = 44/156 (28%), Positives = 70/156 (44%), Gaps = 5/156 (3%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T + AC G + + LL+ G +L+ + +H + G EC+++LL + +
Sbjct: 116 TPLFNACCSGSAACVNVLLEFGAKA-QLEVHLASPIHEAVKRGHRECMEILLANNVNI-- 172
Query: 146 WDSSTETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELL 205
D TPL+ A + + + CVK L+ GA V+ G +PLH A EV+ L
Sbjct: 173 -DHEVPQLGTPLYVACTYQRVDCVKKLLELGASVDHGQWLDTPLHAAARQSNVEVIHLLT 231
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAG 241
+ GA ++ L +AA S LLL G
Sbjct: 232 DYGANLKRRNAQGKSALDLAAPKSSVE-QALLLREG 266
Score = 35.5 bits (78), Expect = 0.69
Identities = 23/66 (34%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 319 RTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYGGD 378
+T + A + G AC A+ LL GA N G TPL A + +ACV +LL++G
Sbjct: 82 KTLIAQACLGGHVAC--AKALLENGAHVNGVTVHGATPLFNACCSGSAACVNVLLEFGAK 139
Query: 379 VTLRTN 384
L +
Sbjct: 140 AQLEVH 145
>AB075861-1|BAB85567.1| 863|Homo sapiens KIAA1981 protein protein.
Length = 863
Score = 93.5 bits (222), Expect = 2e-18
Identities = 74/228 (32%), Positives = 103/228 (45%), Gaps = 8/228 (3%)
Query: 151 ETKATPLHCAASAKSLACVKVLIAHGADVNAGLSDRSPLHYAVLSDAPEVVKELLEAGAC 210
E +A P A A C+ A A + G SD L +DAP V + G
Sbjct: 7 EPRAPPAPRAPDAMKQLCL-CAAASFASQDWGKSDERLLQAVENNDAPRVAALIARKGLV 65
Query: 211 PDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARL 270
P ++ H+AA G+ASC ++++ G++V + G G ALHLAA+ GH +C +
Sbjct: 66 PTKLDPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSTDGAG-YNALHLAAKYGHPQCLKQ 124
Query: 271 LLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGA 330
LL +D + G T LH A L E+L A + +D G TPL + A
Sbjct: 125 LLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSGATPL----IIAA 180
Query: 331 RAC--DIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLDYG 376
+ C D+ RLLL GA N D G T L +A V +LL G
Sbjct: 181 QMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVEVLLQGG 228
Score = 84.2 bits (199), Expect = 2e-15
Identities = 63/191 (32%), Positives = 96/191 (50%), Gaps = 4/191 (2%)
Query: 158 HCAASAKSLACVKVLIAHGADV-NAGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQV 216
H AA + +C++V+IAHG++V + + + LH A P+ +K+LL+A D
Sbjct: 78 HLAAMRGAASCLEVMIAHGSNVMSTDGAGYNALHLAAKYGHPQCLKQLLQASCVVDVVDS 137
Query: 217 FTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGA 276
T LH AA+ G SC+++L + A + G AT L +AA+ H + RLLL GA
Sbjct: 138 SGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSG-ATPLIIAAQMCHTDLCRLLLQQGA 196
Query: 277 HIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAKDADGRTPLHGAIVRGARACDIA 336
+ + +G+T L LA S E VE+L+ A DA G+ H + G + I
Sbjct: 197 AANDQDLQGRTALMLACEGASPETVEVLLQGGAQPGITDALGQDAAHYGALAGDKL--IL 254
Query: 337 RLLLSAGADPN 347
LL A P+
Sbjct: 255 HLLQEAAQRPS 265
Score = 66.5 bits (155), Expect = 3e-10
Identities = 54/203 (26%), Positives = 88/203 (43%), Gaps = 5/203 (2%)
Query: 103 LLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTWDSSTETKATPLHCAAS 162
+ + G+ P +LD G++ HL+ + G+ C+++++ HG++ + D + LH AA
Sbjct: 59 IARKGLVPTKLDPEGKSAFHLAAMRGAASCLEVMIAHGSNVMSTDGA---GYNALHLAAK 115
Query: 163 AKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELLEAGACPDTPQVFTETP 221
C+K L+ V+ S + LH+A + L A + TP
Sbjct: 116 YGHPQCLKQLLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSGATP 175
Query: 222 LHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHAECARLLLDHGAHIDWP 281
L +AA + +LLL GA G+ TAL LA E E +LL GA
Sbjct: 176 LIIAAQMCHTDLCRLLLQQGAAANDQDLQGR-TALMLACEGASPETVEVLLQGGAQPGIT 234
Query: 282 NFRGQTPLHLATLAQSLEVVEML 304
+ GQ H LA ++ +L
Sbjct: 235 DALGQDAAHYGALAGDKLILHLL 257
Score = 63.3 bits (147), Expect = 3e-09
Identities = 56/196 (28%), Positives = 83/196 (42%), Gaps = 4/196 (2%)
Query: 197 APEVVKELLEAGACPDTPQVF--TETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKAT 254
AP+ +K+L A Q + ++ L A A L+ V + P +
Sbjct: 16 APDAMKQLCLCAAASFASQDWGKSDERLLQAVENNDAPRVAALIARKGLVPTKLDPEGKS 75
Query: 255 ALHLAAEDGHAECARLLLDHGAHIDWPNFRGQTPLHLATLAQSLEVVEMLVDRCADVRAK 314
A HLAA G A C +++ HG+++ + G LHLA + ++ L+ V
Sbjct: 76 AFHLAAMRGAASCLEVMIAHGSNVMSTDGAGYNALHLAAKYGHPQCLKQLLQASCVVDVV 135
Query: 315 DADGRTPLHGAIVRGARACDIARLLLSAGADPNAADNFGYTPLHIAALNEFSACVLLLLD 374
D+ G T LH A G +C + +L S A N D G TPL IAA + LLL
Sbjct: 136 DSSGWTALHHAAAGGCLSC--SEVLCSFKAHLNPQDRSGATPLIIAAQMCHTDLCRLLLQ 193
Query: 375 YGGDVTLRTNGGVSAL 390
G + G +AL
Sbjct: 194 QGAAANDQDLQGRTAL 209
Score = 57.6 bits (133), Expect = 2e-07
Identities = 57/190 (30%), Positives = 79/190 (41%), Gaps = 11/190 (5%)
Query: 87 AILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNTW 146
A+ A G L +LL+ D +D +G T LH + G C ++L AH N
Sbjct: 109 ALHLAAKYGHPQCLKQLLQASCVVDVVDSSGWTALHHAAAGGCLSCSEVLCSFKAHLNPQ 168
Query: 147 DSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKELL 205
D S ATPL AA ++L+ GA N L R+ L A +PE V+ LL
Sbjct: 169 DRS---GATPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVEVLL 225
Query: 206 EAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGADVRAAMGPGKATALHLAAEDGHA 265
+ GA P + H A G KL+L+ + AA P +AL + G A
Sbjct: 226 QGGAQPGITDALGQDAAHYGALAGD----KLILHLLQE--AAQRPSPPSAL-TEDDSGEA 278
Query: 266 ECARLLLDHG 275
+ HG
Sbjct: 279 SSQNSMSSHG 288
Score = 54.0 bits (124), Expect = 2e-06
Identities = 46/159 (28%), Positives = 71/159 (44%), Gaps = 4/159 (2%)
Query: 85 RTAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPN 144
++A A G + L ++ G + D AG LHL+ G +C+K LL +
Sbjct: 74 KSAFHLAAMRGAASCLEVMIAHGSNVMSTDGAGYNALHLAAKYGHPQCLKQLLQASCVVD 133
Query: 145 TWDSSTETKATPLHCAASAKSLACVKVLIAHGADVN-AGLSDRSPLHYAVLSDAPEVVKE 203
DSS T LH AA+ L+C +VL + A +N S +PL A ++ +
Sbjct: 134 VVDSS---GWTALHHAAAGGCLSCSEVLCSFKAHLNPQDRSGATPLIIAAQMCHTDLCRL 190
Query: 204 LLEAGACPDTPQVFTETPLHVAASLGSASCTKLLLNAGA 242
LL+ GA + + T L +A S ++LL GA
Sbjct: 191 LLQQGAAANDQDLQGRTALMLACEGASPETVEVLLQGGA 229
Score = 36.7 bits (81), Expect = 0.30
Identities = 22/63 (34%), Positives = 33/63 (52%)
Query: 86 TAILWACWLGKSILLFKLLKMGVDPDELDDAGRTCLHLSCLVGSEECVKLLLDHGAHPNT 145
T ++ A + + L LL+ G ++ D GRT L L+C S E V++LL GA P
Sbjct: 174 TPLIIAAQMCHTDLCRLLLQQGAAANDQDLQGRTALMLACEGASPETVEVLLQGGAQPGI 233
Query: 146 WDS 148
D+
Sbjct: 234 TDA 236
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.136 0.409
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,267,185
Number of Sequences: 224733
Number of extensions: 4398125
Number of successful extensions: 30814
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 947
Number of HSP's successfully gapped in prelim test: 182
Number of HSP's that attempted gapping in prelim test: 10021
Number of HSP's gapped (non-prelim): 7360
length of query: 746
length of database: 73,234,838
effective HSP length: 95
effective length of query: 651
effective length of database: 51,885,203
effective search space: 33777267153
effective search space used: 33777267153
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 69 (31.9 bits)
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