Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005155-TA|BGIBMGA005155-PA|IPR001395|Aldo/keto reductase
(298 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 112 1e-24
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 112 1e-24
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 112 1e-24
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 112 1e-24
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 112 1e-24
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 112 1e-24
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 112 1e-24
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 112 1e-24
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 106 1e-22
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 104 4e-22
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 103 6e-22
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 103 6e-22
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 103 6e-22
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 103 6e-22
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 103 6e-22
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 103 6e-22
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 103 6e-22
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 103 6e-22
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 103 6e-22
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 103 6e-22
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 103 6e-22
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 103 6e-22
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 103 6e-22
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 101 2e-21
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 101 2e-21
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 100 5e-21
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 100 5e-21
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 100 5e-21
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 100 5e-21
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 100 5e-21
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 100 5e-21
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 100 5e-21
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 100 5e-21
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 100 5e-21
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 100 5e-21
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 100 5e-21
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 100 5e-21
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 100 7e-21
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 100 7e-21
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 100 7e-21
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 100 7e-21
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 100 7e-21
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 100 7e-21
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 100 7e-21
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 100 7e-21
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 100 7e-21
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 100 7e-21
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 100 7e-21
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 100 7e-21
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 99 9e-21
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 99 9e-21
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 99 9e-21
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 99 9e-21
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 99 9e-21
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 99 9e-21
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 99 9e-21
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 99 9e-21
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 99 9e-21
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 99 9e-21
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 99 9e-21
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 99 9e-21
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 99 9e-21
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 99 2e-20
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 98 3e-20
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 98 3e-20
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 98 3e-20
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 98 3e-20
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 98 3e-20
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 98 3e-20
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 98 3e-20
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 98 3e-20
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 98 4e-20
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 98 4e-20
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 97 5e-20
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 97 5e-20
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 97 7e-20
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 97 9e-20
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 96 2e-19
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 96 2e-19
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 85 4e-16
AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-relate... 65 3e-10
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 57 9e-08
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 54 8e-07
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 52 2e-06
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 49 2e-05
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 49 2e-05
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 44 6e-04
AY744466-1|AAV30885.1| 278|Homo sapiens FSHD region gene 2 prot... 31 3.7
AY714545-1|AAU14220.1| 278|Homo sapiens FSHD region gene 2 prot... 31 3.7
AY028079-2|AAK21977.1| 278|Homo sapiens FSHD Region Gene 2 prot... 31 3.7
AL731696-1|CAH69901.1| 279|Homo sapiens novel protein similar t... 31 3.7
AL138902-1|CAI22858.2| 626|Homo sapiens grainyhead-like 3 (Dros... 31 4.9
AL031431-1|CAI21407.2| 626|Homo sapiens grainyhead-like 3 (Dros... 31 4.9
AK074386-1|BAB85067.1| 626|Homo sapiens protein ( Homo sapiens ... 31 4.9
D50487-1|BAA09078.1| 1220|Homo sapiens RNA helicase protein. 31 6.4
BC047327-1|AAH47327.2| 1220|Homo sapiens DEAH (Asp-Glu-Ala-His) ... 31 6.4
BC044586-1|AAH44586.2| 1220|Homo sapiens DEAH (Asp-Glu-Ala-His) ... 31 6.4
BC036890-1|AAH36890.1| 555|Homo sapiens GRHL3 protein protein. 31 6.4
AY231160-1|AAO67370.1| 607|Homo sapiens sister-of-mammalian gra... 31 6.4
AL138902-3|CAM12854.1| 556|Homo sapiens grainyhead-like 3 (Dros... 31 6.4
AL138902-2|CAI22857.2| 607|Homo sapiens grainyhead-like 3 (Dros... 31 6.4
AL137763-1|CAB70911.1| 117|Homo sapiens hypothetical protein pr... 31 6.4
AL031431-3|CAM12855.1| 556|Homo sapiens grainyhead-like 3 (Dros... 31 6.4
AL031431-2|CAI21406.2| 607|Homo sapiens grainyhead-like 3 (Dros... 31 6.4
U77782-1|AAB71624.1| 1236|Homo sapiens N-methyl-D-aspartate rece... 30 8.5
L76224-1|AAA88096.1| 1233|Homo sapiens NMDA receptor protein. 30 8.5
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 69/165 (41%), Positives = 91/165 (55%), Gaps = 8/165 (4%)
Query: 112 YKRTKINEVATLLK-LKESGQVRHLGVSNLNLEQLTRLSKIE--KPACLQVEVHLLCQQK 168
Y T E L+ L G V+ LG+SN N Q+ + + +PA LQVE H Q
Sbjct: 135 YDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQN 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L+ + + + AYSPLGS A D P LL+ PVV +AE + RSPAQ+L
Sbjct: 195 ELIAHCQARGLEVTAYSPLGSSD-----RAWRDPDEPVLLEEPVVLALAEKYGRSPAQIL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
LR+ VQR + IPKS P+RI QN+ ++DF S EMK L AL+K
Sbjct: 250 LRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 69/165 (41%), Positives = 91/165 (55%), Gaps = 8/165 (4%)
Query: 112 YKRTKINEVATLLK-LKESGQVRHLGVSNLNLEQLTRLSKIE--KPACLQVEVHLLCQQK 168
Y T E L+ L G V+ LG+SN N Q+ + + +PA LQVE H Q
Sbjct: 135 YDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQN 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L+ + + + AYSPLGS A D P LL+ PVV +AE + RSPAQ+L
Sbjct: 195 ELIAHCQARGLEVTAYSPLGSSD-----RAWRDPDEPVLLEEPVVLALAEKYGRSPAQIL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
LR+ VQR + IPKS P+RI QN+ ++DF S EMK L AL+K
Sbjct: 250 LRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 69/165 (41%), Positives = 91/165 (55%), Gaps = 8/165 (4%)
Query: 112 YKRTKINEVATLLK-LKESGQVRHLGVSNLNLEQLTRLSKIE--KPACLQVEVHLLCQQK 168
Y T E L+ L G V+ LG+SN N Q+ + + +PA LQVE H Q
Sbjct: 135 YDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQN 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L+ + + + AYSPLGS A D P LL+ PVV +AE + RSPAQ+L
Sbjct: 195 ELIAHCQARGLEVTAYSPLGSSD-----RAWRDPDEPVLLEEPVVLALAEKYGRSPAQIL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
LR+ VQR + IPKS P+RI QN+ ++DF S EMK L AL+K
Sbjct: 250 LRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 69/165 (41%), Positives = 91/165 (55%), Gaps = 8/165 (4%)
Query: 112 YKRTKINEVATLLK-LKESGQVRHLGVSNLNLEQLTRLSKIE--KPACLQVEVHLLCQQK 168
Y T E L+ L G V+ LG+SN N Q+ + + +PA LQVE H Q
Sbjct: 135 YDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQN 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L+ + + + AYSPLGS A D P LL+ PVV +AE + RSPAQ+L
Sbjct: 195 ELIAHCQARGLEVTAYSPLGSSD-----RAWRDPDEPVLLEEPVVLALAEKYGRSPAQIL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
LR+ VQR + IPKS P+RI QN+ ++DF S EMK L AL+K
Sbjct: 250 LRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 69/165 (41%), Positives = 91/165 (55%), Gaps = 8/165 (4%)
Query: 112 YKRTKINEVATLLK-LKESGQVRHLGVSNLNLEQLTRLSKIE--KPACLQVEVHLLCQQK 168
Y T E L+ L G V+ LG+SN N Q+ + + +PA LQVE H Q
Sbjct: 135 YDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQN 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L+ + + + AYSPLGS A D P LL+ PVV +AE + RSPAQ+L
Sbjct: 195 ELIAHCQARGLEVTAYSPLGSSD-----RAWRDPDEPVLLEEPVVLALAEKYGRSPAQIL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
LR+ VQR + IPKS P+RI QN+ ++DF S EMK L AL+K
Sbjct: 250 LRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 69/165 (41%), Positives = 91/165 (55%), Gaps = 8/165 (4%)
Query: 112 YKRTKINEVATLLK-LKESGQVRHLGVSNLNLEQLTRLSKIE--KPACLQVEVHLLCQQK 168
Y T E L+ L G V+ LG+SN N Q+ + + +PA LQVE H Q
Sbjct: 135 YDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQN 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L+ + + + AYSPLGS A D P LL+ PVV +AE + RSPAQ+L
Sbjct: 195 ELIAHCQARGLEVTAYSPLGSSD-----RAWRDPDEPVLLEEPVVLALAEKYGRSPAQIL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
LR+ VQR + IPKS P+RI QN+ ++DF S EMK L AL+K
Sbjct: 250 LRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 69/165 (41%), Positives = 91/165 (55%), Gaps = 8/165 (4%)
Query: 112 YKRTKINEVATLLK-LKESGQVRHLGVSNLNLEQLTRLSKIE--KPACLQVEVHLLCQQK 168
Y T E L+ L G V+ LG+SN N Q+ + + +PA LQVE H Q
Sbjct: 135 YDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQN 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L+ + + + AYSPLGS A D P LL+ PVV +AE + RSPAQ+L
Sbjct: 195 ELIAHCQARGLEVTAYSPLGSSD-----RAWRDPDEPVLLEEPVVLALAEKYGRSPAQIL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
LR+ VQR + IPKS P+RI QN+ ++DF S EMK L AL+K
Sbjct: 250 LRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 112 bits (270), Expect = 1e-24
Identities = 69/165 (41%), Positives = 91/165 (55%), Gaps = 8/165 (4%)
Query: 112 YKRTKINEVATLLK-LKESGQVRHLGVSNLNLEQLTRLSKIE--KPACLQVEVHLLCQQK 168
Y T E L+ L G V+ LG+SN N Q+ + + +PA LQVE H Q
Sbjct: 135 YDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQN 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L+ + + + AYSPLGS A D P LL+ PVV +AE + RSPAQ+L
Sbjct: 195 ELIAHCQARGLEVTAYSPLGSSD-----RAWRDPDEPVLLEEPVVLALAEKYGRSPAQIL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
LR+ VQR + IPKS P+RI QN+ ++DF S EMK L AL+K
Sbjct: 250 LRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNK 294
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 106 bits (254), Expect = 1e-22
Identities = 61/172 (35%), Positives = 94/172 (54%), Gaps = 20/172 (11%)
Query: 129 SGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIPIVAY 184
+G V+++GVSN N EQL RL KP Q+E H QK L+ + + + AY
Sbjct: 161 TGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAY 220
Query: 185 SPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAIPKST 244
PLG + DL+ PV+KRIA+ H +SPAQ+L+R+ +QR + IP S
Sbjct: 221 RPLGGSC-----------EGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSI 269
Query: 245 NPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
P+ IK+N+ ++DFEL+ +M ++ +L+ R FP + H ++PF
Sbjct: 270 TPSHIKENIQVFDFELTQHDMDNILSLN-----RNLRLAMFPITKNHNDYPF 316
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 104 bits (249), Expect = 4e-22
Identities = 68/180 (37%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLNLEQLTR-LSKIE---KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N Q+ LSK KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILSKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 103 bits (248), Expect = 6e-22
Identities = 65/180 (36%), Positives = 97/180 (53%), Gaps = 14/180 (7%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 143 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 202
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRG 236
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQVL+R+ +QR
Sbjct: 203 KGIVVTAYSPLGSP---DRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRN 257
Query: 237 LAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
L IPKS P RI +N ++DFELS +M L L R+C H ++PF
Sbjct: 258 LVVIPKSVTPERIAENFKVFDFELSSQDMTTL--LSYNRNWRVCALL---SCTSHKDYPF 312
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 101 bits (243), Expect = 2e-21
Identities = 55/149 (36%), Positives = 86/149 (57%), Gaps = 15/149 (10%)
Query: 129 SGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIPIVAY 184
+G V+++GVSN N EQL RL KP Q+E H QK L+ + + + AY
Sbjct: 161 TGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAY 220
Query: 185 SPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAIPKST 244
PLG + DL+ PV+KRIA+ H +SPAQ+L+R+ +QR + IP S
Sbjct: 221 RPLGGSC-----------EGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSI 269
Query: 245 NPTRIKQNLSIWDFELSDSEMKDLGALDK 273
P+ IK+N+ ++DFEL+ +M ++ +L++
Sbjct: 270 TPSHIKENIQVFDFELTQHDMDNILSLNR 298
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 101 bits (243), Expect = 2e-21
Identities = 55/149 (36%), Positives = 86/149 (57%), Gaps = 15/149 (10%)
Query: 129 SGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIPIVAY 184
+G V+++GVSN N EQL RL KP Q+E H QK L+ + + + AY
Sbjct: 161 TGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAY 220
Query: 185 SPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAIPKST 244
PLG + DL+ PV+KRIA+ H +SPAQ+L+R+ +QR + IP S
Sbjct: 221 RPLGGSC-----------EGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSI 269
Query: 245 NPTRIKQNLSIWDFELSDSEMKDLGALDK 273
P+ IK+N+ ++DFEL+ +M ++ +L++
Sbjct: 270 TPSHIKENIQVFDFELTQHDMDNILSLNR 298
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 136 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 195
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 196 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 251
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 252 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 284
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 13/178 (7%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VA+S LG++ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAHSALGTQRHKLWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPFKN 298
KS N RI++N+ +++F+L+ +MK L L++ + DF + H ++PF +
Sbjct: 269 AKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----VMDHPDYPFSD 321
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 100 bits (240), Expect = 5e-21
Identities = 57/153 (37%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 100 bits (239), Expect = 7e-21
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 113 KRTKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQK 168
K T ++ + +L + G V+ LGVSN + Q+ +L KP QVE H Q+
Sbjct: 135 KATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L++ I + AYSPLGS D AK + P LL+ P +K IA H ++ AQVL
Sbjct: 195 KLIQYCHSKGITVTAYSPLGSP---DRPWAKP--EDPSLLEDPKIKEIAAKHKKTAAQVL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEM 265
+R+ +QR + IPKS P RI +N+ ++DF+LSD EM
Sbjct: 250 IRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEM 286
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 100 bits (239), Expect = 7e-21
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 13/178 (7%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VA+S LG++ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAHSALGTQRHKLWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPFKN 298
KS N RI++N+ +++F+L+ +MK L L++ + DF + H ++PF +
Sbjct: 269 AKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----LMDHPDYPFSD 321
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 100 bits (239), Expect = 7e-21
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 13/178 (7%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q L++ K I
Sbjct: 138 KCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 197
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VA+S LG++ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 198 LVAHSALGTQRHKLWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 253
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPFKN 298
KS N RI++N+ +++F+L+ +MK L L++ + DF + H ++PF +
Sbjct: 254 AKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----LMDHPDYPFSD 306
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 100 bits (239), Expect = 7e-21
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 13/178 (7%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q L++ K I
Sbjct: 151 KCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 210
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VA+S LG++ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 211 LVAHSALGTQRHKLWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 266
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPFKN 298
KS N RI++N+ +++F+L+ +MK L L++ + DF + H ++PF +
Sbjct: 267 AKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----LMDHPDYPFSD 319
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 100 bits (239), Expect = 7e-21
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 113 KRTKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQK 168
K T ++ + +L + G V+ LGVSN + Q+ +L KP QVE H Q+
Sbjct: 135 KATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L++ I + AYSPLGS D AK + P LL+ P +K IA H ++ AQVL
Sbjct: 195 KLIQYCHSKGITVTAYSPLGSP---DRPWAKP--EDPSLLEDPKIKEIAAKHKKTAAQVL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEM 265
+R+ +QR + IPKS P RI +N+ ++DF+LSD EM
Sbjct: 250 IRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEM 286
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 100 bits (239), Expect = 7e-21
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 113 KRTKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQK 168
K T ++ + +L + G V+ LGVSN + Q+ +L KP QVE H Q+
Sbjct: 135 KATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L++ I + AYSPLGS D AK + P LL+ P +K IA H ++ AQVL
Sbjct: 195 KLIQYCHSKGITVTAYSPLGSP---DRPWAKP--EDPSLLEDPKIKEIAAKHKKTAAQVL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEM 265
+R+ +QR + IPKS P RI +N+ ++DF+LSD EM
Sbjct: 250 IRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEM 286
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 100 bits (239), Expect = 7e-21
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 13/178 (7%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VA+S LG++ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAHSALGTQRHKLWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPFKN 298
KS N RI++N+ +++F+L+ +MK L L++ + DF + H ++PF +
Sbjct: 269 AKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----LMDHPDYPFSD 321
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 100 bits (239), Expect = 7e-21
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 113 KRTKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQK 168
K T ++ + +L + G V+ LGVSN + Q+ +L KP QVE H Q+
Sbjct: 135 KATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L++ I + AYSPLGS D AK + P LL+ P +K IA H ++ AQVL
Sbjct: 195 KLIQYCHSKGITVTAYSPLGSP---DRPWAKP--EDPSLLEDPKIKEIAAKHKKTAAQVL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEM 265
+R+ +QR + IPKS P RI +N+ ++DF+LSD EM
Sbjct: 250 IRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEM 286
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 100 bits (239), Expect = 7e-21
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 113 KRTKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQK 168
K T ++ + +L + G V+ LGVSN + Q+ +L KP QVE H Q+
Sbjct: 135 KATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L++ I + AYSPLGS D AK + P LL+ P +K IA H ++ AQVL
Sbjct: 195 KLIQYCHSKGITVTAYSPLGSP---DRPWAKP--EDPSLLEDPKIKEIAAKHKKTAAQVL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEM 265
+R+ +QR + IPKS P RI +N+ ++DF+LSD EM
Sbjct: 250 IRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEM 286
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 100 bits (239), Expect = 7e-21
Identities = 61/157 (38%), Positives = 88/157 (56%), Gaps = 9/157 (5%)
Query: 113 KRTKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQK 168
K T ++ + +L + G V+ LGVSN + Q+ +L KP QVE H Q+
Sbjct: 135 KATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKPVTNQVECHPYLTQE 194
Query: 169 ALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVL 228
L++ I + AYSPLGS D AK + P LL+ P +K IA H ++ AQVL
Sbjct: 195 KLIQYCHSKGITVTAYSPLGSP---DRPWAKP--EDPSLLEDPKIKEIAAKHKKTAAQVL 249
Query: 229 LRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEM 265
+R+ +QR + IPKS P RI +N+ ++DF+LSD EM
Sbjct: 250 IRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEM 286
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 100 bits (239), Expect = 7e-21
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 13/178 (7%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VA+S LG++ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAHSALGTQRHKLWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPFKN 298
KS N RI++N+ +++F+L+ +MK L L++ + DF + H ++PF +
Sbjct: 269 AKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----LMDHPDYPFSD 321
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 100 bits (239), Expect = 7e-21
Identities = 59/178 (33%), Positives = 97/178 (54%), Gaps = 13/178 (7%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VA+S LG++ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAHSALGTQRHKLWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPFKN 298
KS N RI++N+ +++F+L+ +MK L L++ + DF + H ++PF +
Sbjct: 269 AKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----LMDHPDYPFSD 321
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 99 bits (238), Expect = 9e-21
Identities = 64/174 (36%), Positives = 98/174 (56%), Gaps = 13/174 (7%)
Query: 127 KESGQVRHLGVSNLNLEQLTR-LSKI---EKPACLQVEVHLLCQQKALVEAAKKLSIPIV 182
K++G V+ LGVSN N QL L+K KP QVE H Q L++ ++ I I
Sbjct: 158 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVIT 217
Query: 183 AYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAIPK 242
AYSPLG+ + + P LL+ ++ + + ++++ AQ++LR+ +QRG+ IPK
Sbjct: 218 AYSPLGTSRNPIWVNVSS----PPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPK 273
Query: 243 STNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
S N RIK+N I+DF L++ EMKD+ AL+K R + + H E+PF
Sbjct: 274 SFNLERIKENFQIFDFSLTEEEMKDIEALNKNV--RFVELLMW---RDHPEYPF 322
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 99 bits (238), Expect = 9e-21
Identities = 64/174 (36%), Positives = 98/174 (56%), Gaps = 13/174 (7%)
Query: 127 KESGQVRHLGVSNLNLEQLTR-LSKI---EKPACLQVEVHLLCQQKALVEAAKKLSIPIV 182
K++G V+ LGVSN N QL L+K KP QVE H Q L++ ++ I I
Sbjct: 158 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVIT 217
Query: 183 AYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAIPK 242
AYSPLG+ + + P LL+ ++ + + ++++ AQ++LR+ +QRG+ IPK
Sbjct: 218 AYSPLGTSRNPIWVNVSS----PPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPK 273
Query: 243 STNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
S N RIK+N I+DF L++ EMKD+ AL+K R + + H E+PF
Sbjct: 274 SFNLERIKENFQIFDFSLTEEEMKDIEALNKNV--RFVELLMW---RDHPEYPF 322
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 99 bits (238), Expect = 9e-21
Identities = 64/174 (36%), Positives = 98/174 (56%), Gaps = 13/174 (7%)
Query: 127 KESGQVRHLGVSNLNLEQLTR-LSKI---EKPACLQVEVHLLCQQKALVEAAKKLSIPIV 182
K++G V+ LGVSN N QL L+K KP QVE H Q L++ ++ I I
Sbjct: 158 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVIT 217
Query: 183 AYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAIPK 242
AYSPLG+ + + P LL+ ++ + + ++++ AQ++LR+ +QRG+ IPK
Sbjct: 218 AYSPLGTSRNPIWVNVSS----PPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPK 273
Query: 243 STNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
S N RIK+N I+DF L++ EMKD+ AL+K R + + H E+PF
Sbjct: 274 SFNLERIKENFQIFDFSLTEEEMKDIEALNKNV--RFVELLMW---RDHPEYPF 322
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 99 bits (238), Expect = 9e-21
Identities = 64/174 (36%), Positives = 98/174 (56%), Gaps = 13/174 (7%)
Query: 127 KESGQVRHLGVSNLNLEQLTR-LSKI---EKPACLQVEVHLLCQQKALVEAAKKLSIPIV 182
K++G V+ LGVSN N QL L+K KP QVE H Q L++ ++ I I
Sbjct: 158 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVIT 217
Query: 183 AYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAIPK 242
AYSPLG+ + + P LL+ ++ + + ++++ AQ++LR+ +QRG+ IPK
Sbjct: 218 AYSPLGTSRNPIWVNVSS----PPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPK 273
Query: 243 STNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPF 296
S N RIK+N I+DF L++ EMKD+ AL+K R + + H E+PF
Sbjct: 274 SFNLERIKENFQIFDFSLTEEEMKDIEALNKNV--RFVELLMW---RDHPEYPF 322
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 99 bits (238), Expect = 9e-21
Identities = 57/153 (37%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 98.7 bits (235), Expect = 2e-20
Identities = 58/178 (32%), Positives = 97/178 (54%), Gaps = 13/178 (7%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VA+S LG++ + + P LL+ PV+ +A+ H ++PA + LRY +QRG+ +
Sbjct: 213 LVAHSALGTQRHKLWVDPNS----PVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFFPGIEKHAEFPFKN 298
KS N RI++N+ +++F+L+ +MK L L++ + DF + H ++PF +
Sbjct: 269 AKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----LMDHPDYPFSD 321
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 155 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 214
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 215 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 270
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 271 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 303
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 98.3 bits (234), Expect = 3e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 97.9 bits (233), Expect = 4e-20
Identities = 56/153 (36%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ +P C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 97.9 bits (233), Expect = 4e-20
Identities = 56/153 (36%), Positives = 89/153 (58%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ +P C QVE H Q+ L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNHRLLEMILNEPGLKYEPVCNQVECHPYFNQRKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 301
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 97.5 bits (232), Expect = 5e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 97.5 bits (232), Expect = 5e-20
Identities = 56/153 (36%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEIILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 AKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 97.1 bits (231), Expect = 7e-20
Identities = 55/153 (35%), Positives = 87/153 (56%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H + L++ K I
Sbjct: 153 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIV 212
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS+ + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 213 LVAYSALGSQRDKRWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 268
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
+S N RI+QN+ +++F+L+ +MK + LD+
Sbjct: 269 ARSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDR 301
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 96.7 bits (230), Expect = 9e-20
Identities = 56/153 (36%), Positives = 88/153 (57%), Gaps = 8/153 (5%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++ + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 150 KCKDAELAKSIGVSNFNRSTLEMILNKPGLQVKPVCNQVECHPYFNQRKLLDFCKSKDIV 209
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 210 LVAYSALGSLREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 265
Query: 241 PKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
KS N RI+QN+ +++F+L+ EMK + L++
Sbjct: 266 AKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNR 298
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 95.9 bits (228), Expect = 2e-19
Identities = 56/141 (39%), Positives = 79/141 (56%), Gaps = 6/141 (4%)
Query: 153 KPACLQV-EVHLLCQQKALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLP 211
KP C QV E H Q L+E K I +VAYS LGS+ + D P LL+ P
Sbjct: 166 KPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDP----DCPHLLEEP 221
Query: 212 VVKRIAEAHDRSPAQVLLRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGAL 271
++K IA+ H RSP QV LRY +QRG+ + KS + RIK+N I+DFEL+ +MK + L
Sbjct: 222 ILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMKAIDGL 281
Query: 272 DKG-EEGRICDFTFFPGIEKH 291
++ + +FP E++
Sbjct: 282 NRNLRYDNAANHPYFPFSEEY 302
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 95.9 bits (228), Expect = 2e-19
Identities = 56/141 (39%), Positives = 79/141 (56%), Gaps = 6/141 (4%)
Query: 153 KPACLQV-EVHLLCQQKALVEAAKKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLP 211
KP C QV E H Q L+E K I +VAYS LGS+ + D P LL+ P
Sbjct: 166 KPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDP----DCPHLLEEP 221
Query: 212 VVKRIAEAHDRSPAQVLLRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGAL 271
++K IA+ H RSP QV LRY +QRG+ + KS + RIK+N I+DFEL+ +MK + L
Sbjct: 222 ILKSIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPEDMKAIDGL 281
Query: 272 DKG-EEGRICDFTFFPGIEKH 291
++ + +FP E++
Sbjct: 282 NRNLRYDNAANHPYFPFSEEY 302
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 84.6 bits (200), Expect = 4e-16
Identities = 51/133 (38%), Positives = 73/133 (54%), Gaps = 8/133 (6%)
Query: 125 KLKESGQVRHLGVSNLNLEQLTRLSKIE----KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N QL + KP C QVE H Q+ L++ K I
Sbjct: 119 KCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 178
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQVLLRYTVQRGLAAI 240
+VAYS LGS + + P LL+ PV+ +A+ H R+PA + LRY +QRG+ +
Sbjct: 179 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVL 234
Query: 241 PKSTNPTRIKQNL 253
KS N RI+QN+
Sbjct: 235 AKSYNEQRIRQNV 247
>AF044961-1|AAC15671.1| 85|Homo sapiens aldose reductase-related
protein protein.
Length = 85
Score = 64.9 bits (151), Expect = 3e-10
Identities = 27/55 (49%), Positives = 39/55 (70%)
Query: 211 PVVKRIAEAHDRSPAQVLLRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEM 265
P +K IA H ++ AQVL+R+ +QR + IPKS P RI +N+ ++DF+LSD EM
Sbjct: 1 PKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEM 55
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 56.8 bits (131), Expect = 9e-08
Identities = 39/111 (35%), Positives = 61/111 (54%), Gaps = 9/111 (8%)
Query: 121 ATLLKLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKK 176
A + +L + G V+ +G+SN N +E + ++ KPA Q+E H Q+ L++ +
Sbjct: 140 AAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQS 199
Query: 177 LSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPAQV 227
I + AYSPLGS D AK + P LL+ P +K IA H+++ AQV
Sbjct: 200 KGIVVTAYSPLGS---PDRPWAKP--EDPSLLEDPRIKAIAAKHNKTTAQV 245
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 53.6 bits (123), Expect = 8e-07
Identities = 24/71 (33%), Positives = 43/71 (60%), Gaps = 5/71 (7%)
Query: 226 QVLLRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFF 285
Q+L+R+ +QR + IP S P+ IK+N+ ++DFEL+ +M ++ +L+ R F
Sbjct: 194 QILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLN-----RNLRLAMF 248
Query: 286 PGIEKHAEFPF 296
P + H ++PF
Sbjct: 249 PITKNHKDYPF 259
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 52.4 bits (120), Expect = 2e-06
Identities = 23/71 (32%), Positives = 43/71 (60%), Gaps = 5/71 (7%)
Query: 226 QVLLRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDKGEEGRICDFTFF 285
++L+R+ +QR + IP S P+ IK+N+ ++DFEL+ +M ++ +L+ R F
Sbjct: 153 EILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLN-----RNLRLAMF 207
Query: 286 PGIEKHAEFPF 296
P + H ++PF
Sbjct: 208 PITKNHKDYPF 218
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 49.2 bits (112), Expect = 2e-05
Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 8/105 (7%)
Query: 125 KLKESGQVRHLGVSNLN---LEQLTRLSKIE-KPACLQVEVHLLCQQKALVEAAKKLSIP 180
K K++G + +GVSN N LE + ++ KP C QVE H Q+ L++ K I
Sbjct: 166 KCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIV 225
Query: 181 IVAYSPLGSKALADALAAKTGRDYPDLLQLPVVKRIAEAHDRSPA 225
+VAYS LGS + + P LL+ PV+ +A+ +P+
Sbjct: 226 LVAYSALGSHREEPWVDPNS----PVLLEDPVLCALAKKAQANPS 266
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 48.8 bits (111), Expect = 2e-05
Identities = 18/48 (37%), Positives = 35/48 (72%)
Query: 226 QVLLRYTVQRGLAAIPKSTNPTRIKQNLSIWDFELSDSEMKDLGALDK 273
Q+L+R+ +QR + IP S P+ IK+N+ ++DFEL+ +M ++ +L++
Sbjct: 194 QILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNR 241
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 44.0 bits (99), Expect = 6e-04
Identities = 29/67 (43%), Positives = 38/67 (56%), Gaps = 4/67 (5%)
Query: 127 KESGQVRHLGVSNLNLEQLTR-LSKI---EKPACLQVEVHLLCQQKALVEAAKKLSIPIV 182
K++G V+ LGVSN N QL L+K KP QVE H Q L++ ++ I I
Sbjct: 36 KDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVIT 95
Query: 183 AYSPLGS 189
AYSPLG+
Sbjct: 96 AYSPLGT 102
>AY744466-1|AAV30885.1| 278|Homo sapiens FSHD region gene 2 protein
protein.
Length = 278
Score = 31.5 bits (68), Expect = 3.7
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 138 SNLNLEQLTRLSKIEKPACLQVE-VHLLCQQKALVEAAKKLSIPIVAYSPLGSKAL 192
S L EQLT L+++ P C QV+ ++ + Q A V A+ +P P G AL
Sbjct: 200 SPLTCEQLTLLTRLRGPLCAQVQTLYSMATQAAYVFPAESWLVPATLPGP-GESAL 254
>AY714545-1|AAU14220.1| 278|Homo sapiens FSHD region gene 2 protein
protein.
Length = 278
Score = 31.5 bits (68), Expect = 3.7
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 138 SNLNLEQLTRLSKIEKPACLQVE-VHLLCQQKALVEAAKKLSIPIVAYSPLGSKAL 192
S L EQLT L+++ P C QV+ ++ + Q A V A+ +P P G AL
Sbjct: 200 SPLTCEQLTLLTRLRGPLCAQVQTLYSMATQAAYVFPAESWLVPATLPGP-GESAL 254
>AY028079-2|AAK21977.1| 278|Homo sapiens FSHD Region Gene 2 protein
protein.
Length = 278
Score = 31.5 bits (68), Expect = 3.7
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 138 SNLNLEQLTRLSKIEKPACLQVE-VHLLCQQKALVEAAKKLSIPIVAYSPLGSKAL 192
S L EQLT L+++ P C QV+ ++ + Q A V A+ +P P G AL
Sbjct: 200 SPLTCEQLTLLTRLRGPLCAQVQTLYSMATQAAYVFPAESWLVPATLPGP-GESAL 254
>AL731696-1|CAH69901.1| 279|Homo sapiens novel protein similar to
FSHD Region Gene 2 protein protein.
Length = 279
Score = 31.5 bits (68), Expect = 3.7
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 2/56 (3%)
Query: 138 SNLNLEQLTRLSKIEKPACLQVE-VHLLCQQKALVEAAKKLSIPIVAYSPLGSKAL 192
S L EQLT L+++ P C QV+ ++ + Q A V A+ +P P G AL
Sbjct: 201 SPLTCEQLTLLTRLRGPLCAQVQTLYSMATQAAYVFPAESWLVPATLPGP-GESAL 255
>AL138902-1|CAI22858.2| 626|Homo sapiens grainyhead-like 3
(Drosophila) protein.
Length = 626
Score = 31.1 bits (67), Expect = 4.9
Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKNVKDVSDLVGV-H 62
FT+ +E + +K + D++ + L +EV+ +TP LK L+N +S+ G
Sbjct: 495 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNA--ISEKYGFPE 552
Query: 63 NNIHHKTNMEQSWSKVYKSPPPKRHSP 89
NI+ + P RH P
Sbjct: 553 ENIYKVYKKCKRGETSLLHPRLSRHPP 579
>AL031431-1|CAI21407.2| 626|Homo sapiens grainyhead-like 3
(Drosophila) protein.
Length = 626
Score = 31.1 bits (67), Expect = 4.9
Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKNVKDVSDLVGV-H 62
FT+ +E + +K + D++ + L +EV+ +TP LK L+N +S+ G
Sbjct: 495 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRNA--ISEKYGFPE 552
Query: 63 NNIHHKTNMEQSWSKVYKSPPPKRHSP 89
NI+ + P RH P
Sbjct: 553 ENIYKVYKKCKRGETSLLHPRLSRHPP 579
>AK074386-1|BAB85067.1| 626|Homo sapiens protein ( Homo sapiens
cDNA FLJ23806 fis, clone HRC03576. ).
Length = 626
Score = 31.1 bits (67), Expect = 4.9
Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKNVKDVSDLVGV-H 62
FT+ +E + +K + D++ + L +EV+ +TP LK L+N +S+ G
Sbjct: 495 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLRTPDLKGLRNA--ISEKYGFPE 552
Query: 63 NNIHHKTNMEQSWSKVYKSPPPKRHSP 89
NI+ + P RH P
Sbjct: 553 ENIYKVYKKCKRGETSLLHPRLSRHPP 579
>D50487-1|BAA09078.1| 1220|Homo sapiens RNA helicase protein.
Length = 1220
Score = 30.7 bits (66), Expect = 6.4
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 6/99 (6%)
Query: 115 TKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIEKPACLQVEVHLLCQQKALVEAA 174
T + ++ TL L + G + LG L K+ L + VHL C ++ L
Sbjct: 956 TAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKM-----LIMSVHLGCSEEMLT-IV 1009
Query: 175 KKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVV 213
LS+ V Y P +ALAD AK + D L L V
Sbjct: 1010 SMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAV 1048
>BC047327-1|AAH47327.2| 1220|Homo sapiens DEAH (Asp-Glu-Ala-His) box
polypeptide 8 protein.
Length = 1220
Score = 30.7 bits (66), Expect = 6.4
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 6/99 (6%)
Query: 115 TKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIEKPACLQVEVHLLCQQKALVEAA 174
T + ++ TL L + G + LG L K+ L + VHL C ++ L
Sbjct: 956 TAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKM-----LIMSVHLGCSEEMLT-IV 1009
Query: 175 KKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVV 213
LS+ V Y P +ALAD AK + D L L V
Sbjct: 1010 SMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAV 1048
>BC044586-1|AAH44586.2| 1220|Homo sapiens DEAH (Asp-Glu-Ala-His) box
polypeptide 8 protein.
Length = 1220
Score = 30.7 bits (66), Expect = 6.4
Identities = 30/99 (30%), Positives = 42/99 (42%), Gaps = 6/99 (6%)
Query: 115 TKINEVATLLKLKESGQVRHLGVSNLNLEQLTRLSKIEKPACLQVEVHLLCQQKALVEAA 174
T + ++ TL L + G + LG L K+ L + VHL C ++ L
Sbjct: 956 TAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKM-----LIMSVHLGCSEEMLT-IV 1009
Query: 175 KKLSIPIVAYSPLGSKALADALAAKTGRDYPDLLQLPVV 213
LS+ V Y P +ALAD AK + D L L V
Sbjct: 1010 SMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAV 1048
>BC036890-1|AAH36890.1| 555|Homo sapiens GRHL3 protein protein.
Length = 555
Score = 30.7 bits (66), Expect = 6.4
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKN 51
FT+ +E + +K + D++ + L +EV+ +TP LK L+N
Sbjct: 448 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRN 495
>AY231160-1|AAO67370.1| 607|Homo sapiens sister-of-mammalian
grainyhead isoform 1 protein.
Length = 607
Score = 30.7 bits (66), Expect = 6.4
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKN 51
FT+ +E + +K + D++ + L +EV+ +TP LK L+N
Sbjct: 500 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRN 547
>AL138902-3|CAM12854.1| 556|Homo sapiens grainyhead-like 3
(Drosophila) protein.
Length = 556
Score = 30.7 bits (66), Expect = 6.4
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKN 51
FT+ +E + +K + D++ + L +EV+ +TP LK L+N
Sbjct: 449 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRN 496
>AL138902-2|CAI22857.2| 607|Homo sapiens grainyhead-like 3
(Drosophila) protein.
Length = 607
Score = 30.7 bits (66), Expect = 6.4
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKN 51
FT+ +E + +K + D++ + L +EV+ +TP LK L+N
Sbjct: 500 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRN 547
>AL137763-1|CAB70911.1| 117|Homo sapiens hypothetical protein
protein.
Length = 117
Score = 30.7 bits (66), Expect = 6.4
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKN 51
FT+ +E + +K + D++ + L +EV+ +TP LK L+N
Sbjct: 10 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRN 57
>AL031431-3|CAM12855.1| 556|Homo sapiens grainyhead-like 3
(Drosophila) protein.
Length = 556
Score = 30.7 bits (66), Expect = 6.4
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKN 51
FT+ +E + +K + D++ + L +EV+ +TP LK L+N
Sbjct: 449 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRN 496
>AL031431-2|CAI21406.2| 607|Homo sapiens grainyhead-like 3
(Drosophila) protein.
Length = 607
Score = 30.7 bits (66), Expect = 6.4
Identities = 14/48 (29%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 5 FTDSYE-VNNKNKQYSDIKNIKLNANYRNDEVYQECSYQTPTLKSLKN 51
FT+ +E + +K + D++ + L +EV+ +TP LK L+N
Sbjct: 500 FTEEFEPLPSKQAKEGDLQRVLLYVRRETEEVFDALMLKTPDLKGLRN 547
>U77782-1|AAB71624.1| 1236|Homo sapiens N-methyl-D-aspartate
receptor 2C subunit precursor protein.
Length = 1236
Score = 30.3 bits (65), Expect = 8.5
Identities = 13/45 (28%), Positives = 23/45 (51%)
Query: 40 SYQTPTLKSLKNVKDVSDLVGVHNNIHHKTNMEQSWSKVYKSPPP 84
S Q LK L+ +D+ GV +++ T ++W ++PPP
Sbjct: 888 SAQASVLKMLQAARDMVTTAGVSSSLDRATRTIENWGGGRRAPPP 932
>L76224-1|AAA88096.1| 1233|Homo sapiens NMDA receptor protein.
Length = 1233
Score = 30.3 bits (65), Expect = 8.5
Identities = 13/45 (28%), Positives = 23/45 (51%)
Query: 40 SYQTPTLKSLKNVKDVSDLVGVHNNIHHKTNMEQSWSKVYKSPPP 84
S Q LK L+ +D+ GV +++ T ++W ++PPP
Sbjct: 888 SAQASVLKMLQAARDMVTTAGVSSSLDRATRTIENWGGGRRAPPP 932
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.314 0.131 0.374
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 41,544,193
Number of Sequences: 224733
Number of extensions: 1597372
Number of successful extensions: 2596
Number of sequences better than 10.0: 106
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 2358
Number of HSP's gapped (non-prelim): 108
length of query: 298
length of database: 73,234,838
effective HSP length: 90
effective length of query: 208
effective length of database: 53,008,868
effective search space: 11025844544
effective search space used: 11025844544
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)
S2: 65 (30.3 bits)
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