GeneModel BLAST Result against human

BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA005151-TA|BGIBMGA005151-PA|IPR001208|MCM,
IPR008994|Nucleic acid-binding, OB-fold, IPR008048|MCM protein 5
         (675 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

Z82244-2|CAB05110.1|  733|Homo sapiens MCM5 minichromosome maint...   791   0.0  
X74795-1|CAA52802.2|  734|Homo sapiens P1 Cdc46 protein.              791   0.0  
CR456517-1|CAG30403.1|  734|Homo sapiens MCM5 protein.                791   0.0  
BC000142-1|AAH00142.1|  734|Homo sapiens minichromosome maintena...   791   0.0  
AY212028-1|AAO21127.1|  734|Homo sapiens MCM5 minichromosome mai...   791   0.0  
D83986-1|BAA12176.1|  733|Homo sapiens huMCM5 protein.                790   0.0  
BC003656-1|AAH03656.1|  734|Homo sapiens minichromosome maintena...   789   0.0  
AK223323-1|BAD97043.1|  734|Homo sapiens minichromosome maintena...   789   0.0  
AB209612-1|BAD92849.1|  418|Homo sapiens minichromosome maintena...   405   e-112
X74796-1|CAA52803.1|  617|Homo sapiens p85Mcm protein protein.        290   1e-77
D55716-1|BAA09534.1|  719|Homo sapiens P1cdc47 protein.               290   1e-77
BC013375-1|AAH13375.1|  719|Homo sapiens minichromosome maintena...   290   1e-77
X74794-1|CAA52801.1|  923|Homo sapiens P1 Cdc21 protein protein.      284   6e-76
U63630-1|AAC52018.1|  712|Homo sapiens MCM4 protein.                  283   1e-75
BC031061-1|AAH31061.1|  863|Homo sapiens minichromosome maintena...   283   1e-75
AY588245-1|AAS83108.1|  863|Homo sapiens MCM4 minichromosome mai...   283   1e-75
D21063-1|BAA04642.1|  914|Homo sapiens KIAA0030 protein.              273   1e-72
BT009734-1|AAP88736.1|  895|Homo sapiens MCM2 minichromosome mai...   273   1e-72
BC030131-1|AAH30131.2|  808|Homo sapiens MCM2 protein protein.        273   1e-72
BC017490-1|AAH17490.2|  904|Homo sapiens minichromosome maintena...   273   1e-72
BC014272-1|AAH14272.2|  904|Homo sapiens minichromosome maintena...   273   1e-72
BC007938-1|AAH07938.2|  904|Homo sapiens minichromosome maintena...   273   1e-72
BC007670-1|AAH07670.2|  904|Homo sapiens minichromosome maintena...   273   1e-72
BC006165-1|AAH06165.3|  904|Homo sapiens minichromosome maintena...   273   1e-72
AY675259-1|AAT70723.1|  904|Homo sapiens MCM2 minichromosome mai...   273   1e-72
D28480-1|BAA05839.1|  543|Homo sapiens hMCM2 protein.                 272   3e-72
BC017258-1|AAH17258.2|  904|Homo sapiens minichromosome maintena...   270   1e-71
D83987-1|BAA12177.1|  895|Homo sapiens huMCM2 protein.                270   1e-71
X62153-1|CAA44078.2|  808|Homo sapiens P1.h protein protein.          266   2e-70
BC003509-1|AAH03509.2|  808|Homo sapiens minichromosome maintena...   266   2e-70
BC001626-1|AAH01626.1|  808|Homo sapiens minichromosome maintena...   266   2e-70
AY621074-1|AAT27321.1|  808|Homo sapiens MCM3 minichromosome mai...   266   2e-70
AY032603-1|AAK56392.1|  676|Homo sapiens cervical cancer proto-o...   266   2e-70
AL034343-1|CAB75298.1|  808|Homo sapiens MCM3 minichromosome mai...   266   2e-70
AK222586-1|BAD96306.1|  808|Homo sapiens minichromosome maintena...   266   2e-70
D38073-1|BAA07267.1|  808|Homo sapiens hRlf beta subunit (p102 p...   262   2e-69
X67334-1|CAA47749.1|  892|Homo sapiens polypeptide BM28 protein.      261   7e-69
D84557-1|BAA12699.1|  821|Homo sapiens HsMcm6 protein.                227   1e-58
BC032374-1|AAH32374.1|  821|Homo sapiens minichromosome maintena...   227   1e-58
AY220757-1|AAO26043.1|  821|Homo sapiens MCM6 minichromosome mai...   227   1e-58
AC011893-4|AAX88925.1|  785|Homo sapiens unknown protein.             227   1e-58
U46838-1|AAC50766.1|  821|Homo sapiens p105MCM protein.               217   8e-56
AY007130-1|AAG01994.1|  351|Homo sapiens protein ( Homo sapiens ...   209   2e-53
BC101057-1|AAI01058.1|  840|Homo sapiens MCM8 protein protein.        203   1e-51
BC101056-1|AAI01057.1|  840|Homo sapiens minichromosome maintena...   203   1e-51
BC080656-1|AAH80656.1|  840|Homo sapiens minichromosome maintena...   203   1e-51
BC008830-1|AAH08830.2|  735|Homo sapiens MCM8 protein protein.        203   1e-51
AL035461-6|CAB55276.2|  840|Homo sapiens MCM8 minichromosome mai...   203   1e-51
AJ439063-1|CAD27750.1|  840|Homo sapiens minichromosome maintena...   203   1e-51
AY158211-1|AAO21222.1|  824|Homo sapiens MCM8 isoform protein.        202   2e-51
AL035461-7|CAI23480.1|  824|Homo sapiens MCM8 minichromosome mai...   202   2e-51
AK027644-1|BAB55260.1|  603|Homo sapiens protein ( Homo sapiens ...   186   2e-46
AK160378-1|BAD18721.1|  450|Homo sapiens FLJ00323 protein protein.    157   2e-37
BC101055-1|AAI01056.1|  880|Homo sapiens MCM8 protein protein.        153   1e-36
BC000300-1|AAH00300.2|  362|Homo sapiens MCM2 protein protein.        149   3e-35
BC101054-1|AAI01055.1|  793|Homo sapiens MCM8 protein protein.        119   4e-26
AL132874-5|CAI42607.1|  451|Homo sapiens protein ( an).  ).).         114   8e-25
BC031658-1|AAH31658.1|  391|Homo sapiens minichromosome maintena...   104   1e-21
AL132874-4|CAI42606.1|  156|Homo sapiens protein ( Human DNA seq...    74   2e-12
BC009398-1|AAH09398.1|  389|Homo sapiens MCM7 protein protein.         57   2e-07
BC093974-1|AAH93974.1|  584|Homo sapiens epsin 2 protein.              35   1.1  
BC093972-1|AAH93972.1|  584|Homo sapiens epsin 2 protein.              35   1.1  
AK024115-1|BAB14831.1|  371|Homo sapiens protein ( Homo sapiens ...    35   1.1  
AF062085-1|AAC78609.1|  642|Homo sapiens epsin 2b protein.             35   1.1  
AF062084-1|AAC78608.1|  584|Homo sapiens epsin 2a protein.             35   1.1  
AB028988-1|BAA83017.2|  665|Homo sapiens KIAA1065 protein protein.     35   1.1  
BC041613-1|AAH41613.1|  348|Homo sapiens transcription elongatio...    33   4.4  
AL357134-3|CAI22178.1|  348|Homo sapiens transcription elongatio...    33   4.4  
AL109936-2|CAI19025.1|  348|Homo sapiens transcription elongatio...    33   4.4  
AJ223473-1|CAA11393.1|  320|Homo sapiens transcription elongatio...    33   4.4  
Y08768-1|CAA70021.1|  380|Homo sapiens IL-13 receptor protein.         32   7.6  
X95302-1|CAA64617.1|  380|Homo sapiens interleukin 13 receptor p...    32   7.6  
U70981-1|AAB17170.1|  380|Homo sapiens interleukin-13 receptor p...    32   7.6  
BC126472-1|AAI26473.1|  452|Homo sapiens tripartite motif-contai...    32   7.6  
BC126470-1|AAI26471.1|  452|Homo sapiens tripartite motif-contai...    32   7.6  
BC075020-1|AAH75020.1|  452|Homo sapiens ring finger protein 18 ...    32   7.6  
BC075019-1|AAH75019.1|  452|Homo sapiens tripartite motif-contai...    32   7.6  
BC033705-1|AAH33705.1|  380|Homo sapiens interleukin 13 receptor...    32   7.6  
BC020739-1|AAH20739.1|  380|Homo sapiens interleukin 13 receptor...    32   7.6  
AY656702-1|AAT49099.1|  380|Homo sapiens interleukin 13 receptor...    32   7.6  
AL121878-1|CAD18962.1|  380|Homo sapiens interleukin 13 receptor...    32   7.6  
AB037682-1|BAB03503.1|  452|Homo sapiens testis-specific RING Fi...    32   7.6  

>Z82244-2|CAB05110.1|  733|Homo sapiens MCM5 minichromosome
           maintenance deficient 5, cellr) protein.
          Length = 733

 Score =  791 bits (1957), Expect = 0.0
 Identities = 364/555 (65%), Positives = 448/555 (80%), Gaps = 8/555 (1%)

Query: 1   MEGFDDPGVFFSDNFGVEENESQDHVNLQAVKKKFKEFMRQFHTGN----FNYKYRDALK 56
           M GFDDPG+F+SD+FG +    +       ++++FKEF+RQ+  G     F +KYRD LK
Sbjct: 1   MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK 60

Query: 57  RNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEK 116
           R+YNL +YW+E+ +EDL+SFD+ LA+ LYK+P EHL +              PRP GEE 
Sbjct: 61  RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV 120

Query: 117 VEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIP 176
           ++DIQV+L SDA  S++R LKS+ +S LVKIPGI+I+AS ++AKAT+ISIQCRSCRN + 
Sbjct: 121 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT 180

Query: 177 NLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGE 236
           N+ ++PGLEGY +PRKCNT+Q+GRPKCPLDPYFI+PDKCKC+D+Q LKLQE P+++P GE
Sbjct: 181 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE 240

Query: 237 MPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLT 296
           MPRH+ +YCDR LC++V PG RVT++GIYSIKK       GRD+  VG+RSSY+R +G+ 
Sbjct: 241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ 300

Query: 297 AEEGVT--SGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGG 354
            +   +  S     + +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGG
Sbjct: 301 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG 360

Query: 355 SRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIR 414
           SRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+R
Sbjct: 361 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR 420

Query: 415 DPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 474
           DP SRNF+MEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
Sbjct: 421 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 480

Query: 475 RCSVLAAANSVFGRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRD-IARYVL-MRT 532
           RCSVLAAANSVFGRWD+TK +DNIDFMPTILSRFDMIFIVKDEH++ RD +A++V+ +  
Sbjct: 481 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDMLAKHVITLHV 540

Query: 533 GALQHERQADKRLSI 547
            AL   +  +  + +
Sbjct: 541 SALTQTQAVEGEIDL 555



 Score =  237 bits (580), Expect = 9e-62
 Identities = 110/149 (73%), Positives = 137/149 (91%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MR+GA QHER +D+R SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 584 RYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 643

Query: 586 QVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQTIIQDFLRQKYP 645
           QVSTLDAA++G+L+G EGFT++ED EML+R+EKQLKRRFA+GSQVSE +II+DF +QKYP
Sbjct: 644 QVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYP 703

Query: 646 ERAILKVIHMMIRRGELQHRLQRKMLYRL 674
           E AI KV+ +M+RRGE+QHR+QRK+LYRL
Sbjct: 704 EHAIHKVLQLMLRRGEIQHRMQRKVLYRL 732


>X74795-1|CAA52802.2|  734|Homo sapiens P1 Cdc46 protein.
          Length = 734

 Score =  791 bits (1956), Expect = 0.0
 Identities = 364/556 (65%), Positives = 448/556 (80%), Gaps = 9/556 (1%)

Query: 1   MEGFDDPGVFFSDNFGVEENESQDHVNLQAVKKKFKEFMRQFHTGN----FNYKYRDALK 56
           M GFDDPG+F+SD+FG +    +       ++++FKEF+RQ+  G     F +KYRD LK
Sbjct: 1   MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK 60

Query: 57  RNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEK 116
           R+YNL +YW+E+ +EDL+SFD+ LA+ LYK+P EHL +              PRP GEE 
Sbjct: 61  RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV 120

Query: 117 VEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIP 176
           ++DIQV+L SDA  S++R LKS+ +S LVKIPGI+I+AS ++AKAT+ISIQCRSCRN + 
Sbjct: 121 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT 180

Query: 177 NLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGE 236
           N+ ++PGLEGY +PRKCNT+Q+GRPKCPLDPYFI+PDKCKC+D+Q LKLQE P+++P GE
Sbjct: 181 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE 240

Query: 237 MPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLT 296
           MPRH+ +YCDR LC++V PG RVT++GIYSIKK       GRD+  VG+RSSY+R +G+ 
Sbjct: 241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ 300

Query: 297 AEEGVT--SGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGG 354
            +   +  S     + +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGG
Sbjct: 301 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG 360

Query: 355 SRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIR 414
           SRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+R
Sbjct: 361 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR 420

Query: 415 DPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 474
           DP SRNF+MEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
Sbjct: 421 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 480

Query: 475 RCSVLAAANSVFGRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDI--ARYVL-MR 531
           RCSVLAAANSVFGRWD+TK +DNIDFMPTILSRFDMIFIVKDEH++ RD+  A++V+ + 
Sbjct: 481 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH 540

Query: 532 TGALQHERQADKRLSI 547
             AL   +  +  + +
Sbjct: 541 VSALTQTQAVEGEIDL 556



 Score =  237 bits (580), Expect = 9e-62
 Identities = 110/149 (73%), Positives = 137/149 (91%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MR+GA QHER +D+R SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 585 RYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 644

Query: 586 QVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQTIIQDFLRQKYP 645
           QVSTLDAA++G+L+G EGFT++ED EML+R+EKQLKRRFA+GSQVSE +II+DF +QKYP
Sbjct: 645 QVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYP 704

Query: 646 ERAILKVIHMMIRRGELQHRLQRKMLYRL 674
           E AI KV+ +M+RRGE+QHR+QRK+LYRL
Sbjct: 705 EHAIHKVLQLMLRRGEIQHRMQRKVLYRL 733


>CR456517-1|CAG30403.1|  734|Homo sapiens MCM5 protein.
          Length = 734

 Score =  791 bits (1956), Expect = 0.0
 Identities = 364/556 (65%), Positives = 448/556 (80%), Gaps = 9/556 (1%)

Query: 1   MEGFDDPGVFFSDNFGVEENESQDHVNLQAVKKKFKEFMRQFHTGN----FNYKYRDALK 56
           M GFDDPG+F+SD+FG +    +       ++++FKEF+RQ+  G     F +KYRD LK
Sbjct: 1   MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK 60

Query: 57  RNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEK 116
           R+YNL +YW+E+ +EDL+SFD+ LA+ LYK+P EHL +              PRP GEE 
Sbjct: 61  RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV 120

Query: 117 VEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIP 176
           ++DIQV+L SDA  S++R LKS+ +S LVKIPGI+I+AS ++AKAT+ISIQCRSCRN + 
Sbjct: 121 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT 180

Query: 177 NLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGE 236
           N+ ++PGLEGY +PRKCNT+Q+GRPKCPLDPYFI+PDKCKC+D+Q LKLQE P+++P GE
Sbjct: 181 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE 240

Query: 237 MPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLT 296
           MPRH+ +YCDR LC++V PG RVT++GIYSIKK       GRD+  VG+RSSY+R +G+ 
Sbjct: 241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ 300

Query: 297 AEEGVT--SGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGG 354
            +   +  S     + +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGG
Sbjct: 301 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG 360

Query: 355 SRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIR 414
           SRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+R
Sbjct: 361 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR 420

Query: 415 DPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 474
           DP SRNF+MEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
Sbjct: 421 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 480

Query: 475 RCSVLAAANSVFGRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDI--ARYVL-MR 531
           RCSVLAAANSVFGRWD+TK +DNIDFMPTILSRFDMIFIVKDEH++ RD+  A++V+ + 
Sbjct: 481 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH 540

Query: 532 TGALQHERQADKRLSI 547
             AL   +  +  + +
Sbjct: 541 VSALTQTQAVEGEIDL 556



 Score =  237 bits (580), Expect = 9e-62
 Identities = 110/149 (73%), Positives = 137/149 (91%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MR+GA QHER +D+R SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 585 RYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 644

Query: 586 QVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQTIIQDFLRQKYP 645
           QVSTLDAA++G+L+G EGFT++ED EML+R+EKQLKRRFA+GSQVSE +II+DF +QKYP
Sbjct: 645 QVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYP 704

Query: 646 ERAILKVIHMMIRRGELQHRLQRKMLYRL 674
           E AI KV+ +M+RRGE+QHR+QRK+LYRL
Sbjct: 705 EHAIHKVLQLMLRRGEIQHRMQRKVLYRL 733


>BC000142-1|AAH00142.1|  734|Homo sapiens minichromosome maintenance
           complex component 5 protein.
          Length = 734

 Score =  791 bits (1956), Expect = 0.0
 Identities = 364/556 (65%), Positives = 448/556 (80%), Gaps = 9/556 (1%)

Query: 1   MEGFDDPGVFFSDNFGVEENESQDHVNLQAVKKKFKEFMRQFHTGN----FNYKYRDALK 56
           M GFDDPG+F+SD+FG +    +       ++++FKEF+RQ+  G     F +KYRD LK
Sbjct: 1   MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK 60

Query: 57  RNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEK 116
           R+YNL +YW+E+ +EDL+SFD+ LA+ LYK+P EHL +              PRP GEE 
Sbjct: 61  RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV 120

Query: 117 VEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIP 176
           ++DIQV+L SDA  S++R LKS+ +S LVKIPGI+I+AS ++AKAT+ISIQCRSCRN + 
Sbjct: 121 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT 180

Query: 177 NLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGE 236
           N+ ++PGLEGY +PRKCNT+Q+GRPKCPLDPYFI+PDKCKC+D+Q LKLQE P+++P GE
Sbjct: 181 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE 240

Query: 237 MPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLT 296
           MPRH+ +YCDR LC++V PG RVT++GIYSIKK       GRD+  VG+RSSY+R +G+ 
Sbjct: 241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ 300

Query: 297 AEEGVT--SGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGG 354
            +   +  S     + +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGG
Sbjct: 301 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG 360

Query: 355 SRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIR 414
           SRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+R
Sbjct: 361 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR 420

Query: 415 DPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 474
           DP SRNF+MEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
Sbjct: 421 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 480

Query: 475 RCSVLAAANSVFGRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDI--ARYVL-MR 531
           RCSVLAAANSVFGRWD+TK +DNIDFMPTILSRFDMIFIVKDEH++ RD+  A++V+ + 
Sbjct: 481 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH 540

Query: 532 TGALQHERQADKRLSI 547
             AL   +  +  + +
Sbjct: 541 VSALTQTQAVEGEIDL 556



 Score =  237 bits (580), Expect = 9e-62
 Identities = 110/149 (73%), Positives = 137/149 (91%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MR+GA QHER +D+R SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 585 RYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 644

Query: 586 QVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQTIIQDFLRQKYP 645
           QVSTLDAA++G+L+G EGFT++ED EML+R+EKQLKRRFA+GSQVSE +II+DF +QKYP
Sbjct: 645 QVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYP 704

Query: 646 ERAILKVIHMMIRRGELQHRLQRKMLYRL 674
           E AI KV+ +M+RRGE+QHR+QRK+LYRL
Sbjct: 705 EHAIHKVLQLMLRRGEIQHRMQRKVLYRL 733


>AY212028-1|AAO21127.1|  734|Homo sapiens MCM5 minichromosome
           maintenance deficient 5, cell division cycle 46 (S.
           cerevis protein.
          Length = 734

 Score =  791 bits (1956), Expect = 0.0
 Identities = 364/556 (65%), Positives = 448/556 (80%), Gaps = 9/556 (1%)

Query: 1   MEGFDDPGVFFSDNFGVEENESQDHVNLQAVKKKFKEFMRQFHTGN----FNYKYRDALK 56
           M GFDDPG+F+SD+FG +    +       ++++FKEF+RQ+  G     F +KYRD LK
Sbjct: 1   MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK 60

Query: 57  RNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEK 116
           R+YNL +YW+E+ +EDL+SFD+ LA+ LYK+P EHL +              PRP GEE 
Sbjct: 61  RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV 120

Query: 117 VEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIP 176
           ++DIQV+L SDA  S++R LKS+ +S LVKIPGI+I+AS ++AKAT+ISIQCRSCRN + 
Sbjct: 121 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT 180

Query: 177 NLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGE 236
           N+ ++PGLEGY +PRKCNT+Q+GRPKCPLDPYFI+PDKCKC+D+Q LKLQE P+++P GE
Sbjct: 181 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE 240

Query: 237 MPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLT 296
           MPRH+ +YCDR LC++V PG RVT++GIYSIKK       GRD+  VG+RSSY+R +G+ 
Sbjct: 241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ 300

Query: 297 AEEGVT--SGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGG 354
            +   +  S     + +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGG
Sbjct: 301 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG 360

Query: 355 SRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIR 414
           SRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+R
Sbjct: 361 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR 420

Query: 415 DPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 474
           DP SRNF+MEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
Sbjct: 421 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 480

Query: 475 RCSVLAAANSVFGRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDI--ARYVL-MR 531
           RCSVLAAANSVFGRWD+TK +DNIDFMPTILSRFDMIFIVKDEH++ RD+  A++V+ + 
Sbjct: 481 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH 540

Query: 532 TGALQHERQADKRLSI 547
             AL   +  +  + +
Sbjct: 541 VSALTQTQAVEGEIDL 556



 Score =  237 bits (580), Expect = 9e-62
 Identities = 110/149 (73%), Positives = 137/149 (91%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MR+GA QHER +D+R SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 585 RYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 644

Query: 586 QVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQTIIQDFLRQKYP 645
           QVSTLDAA++G+L+G EGFT++ED EML+R+EKQLKRRFA+GSQVSE +II+DF +QKYP
Sbjct: 645 QVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYP 704

Query: 646 ERAILKVIHMMIRRGELQHRLQRKMLYRL 674
           E AI KV+ +M+RRGE+QHR+QRK+LYRL
Sbjct: 705 EHAIHKVLQLMLRRGEIQHRMQRKVLYRL 733


>D83986-1|BAA12176.1|  733|Homo sapiens huMCM5 protein.
          Length = 733

 Score =  790 bits (1953), Expect = 0.0
 Identities = 364/556 (65%), Positives = 448/556 (80%), Gaps = 9/556 (1%)

Query: 1   MEGFDDPGVFFSDNFGVEENESQDHVNLQAVKKKFKEFMRQFHTGN----FNYKYRDALK 56
           M GFDDPG+F+SD+FG +    +       ++++FKEF+RQ+  G     F +KYRD LK
Sbjct: 1   MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK 60

Query: 57  RNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEK 116
           R+YNL +YW+E+ +EDL+SFD+ LA+ LYK+P EHL +              PRP GEE 
Sbjct: 61  RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV 120

Query: 117 VEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIP 176
           ++DIQV+L SDA  S++R LKS+ +S LVKIPGI+I+AS ++AKAT+ISIQCRSCRN + 
Sbjct: 121 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT 180

Query: 177 NLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGE 236
           N+ ++PGLEGY +PRKCNT+Q+GRPKCPLDPYFI+PDKCKC+D+Q LKLQE P+++P GE
Sbjct: 181 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE 240

Query: 237 MPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLT 296
           MPRH+ +YCDR LC++V PG RVT++GIYSIKK       GRD+  VG+RSSY+R +G+ 
Sbjct: 241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ 300

Query: 297 AEEGVT--SGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGG 354
            +   +  S     + +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGG
Sbjct: 301 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG 360

Query: 355 SRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIR 414
           SRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+R
Sbjct: 361 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR 420

Query: 415 DPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 474
           DP SRNF+MEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
Sbjct: 421 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 480

Query: 475 RCSVLAAANSVFGRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDI--ARYVL-MR 531
           RCSVLAAANSVFGRWD+TK +DNIDFMPTILSRFDMIFIVKDEH++ RD+  A++V+ + 
Sbjct: 481 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEVRDVMLAKHVITLH 540

Query: 532 TGALQHERQADKRLSI 547
             AL   +  +  + +
Sbjct: 541 VSALTQTQAVEGEIDL 556



 Score =  217 bits (531), Expect = 8e-56
 Identities = 105/149 (70%), Positives = 130/149 (87%), Gaps = 1/149 (0%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MRTG +   R      SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 585 RYIIMRTGPVS-TRGTVTASSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 643

Query: 586 QVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQTIIQDFLRQKYP 645
           QVSTLDAA++G+L+G EGFT++ED EML+R+EKQLKRRFA+GSQVSE +II+DF +QKYP
Sbjct: 644 QVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYP 703

Query: 646 ERAILKVIHMMIRRGELQHRLQRKMLYRL 674
           E AI KV+ +M+RRGE+QHR+QRK+LYRL
Sbjct: 704 EHAIHKVLQLMLRRGEIQHRMQRKVLYRL 732


>BC003656-1|AAH03656.1|  734|Homo sapiens minichromosome maintenance
           complex component 5 protein.
          Length = 734

 Score =  789 bits (1952), Expect = 0.0
 Identities = 363/556 (65%), Positives = 448/556 (80%), Gaps = 9/556 (1%)

Query: 1   MEGFDDPGVFFSDNFGVEENESQDHVNLQAVKKKFKEFMRQFHTGN----FNYKYRDALK 56
           M GFDDPG+F+SD+FG +    +       ++++FKEF+R++  G     F +KYRD LK
Sbjct: 1   MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRRYRVGTDRTGFTFKYRDELK 60

Query: 57  RNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEK 116
           R+YNL +YW+E+ +EDL+SFD+ LA+ LYK+P EHL +              PRP GEE 
Sbjct: 61  RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV 120

Query: 117 VEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIP 176
           ++DIQV+L SDA  S++R LKS+ +S LVKIPGI+I+AS ++AKAT+ISIQCRSCRN + 
Sbjct: 121 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT 180

Query: 177 NLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGE 236
           N+ ++PGLEGY +PRKCNT+Q+GRPKCPLDPYFI+PDKCKC+D+Q LKLQE P+++P GE
Sbjct: 181 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE 240

Query: 237 MPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLT 296
           MPRH+ +YCDR LC++V PG RVT++GIYSIKK       GRD+  VG+RSSY+R +G+ 
Sbjct: 241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ 300

Query: 297 AEEGVT--SGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGG 354
            +   +  S     + +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGG
Sbjct: 301 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG 360

Query: 355 SRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIR 414
           SRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+R
Sbjct: 361 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR 420

Query: 415 DPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 474
           DP SRNF+MEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
Sbjct: 421 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 480

Query: 475 RCSVLAAANSVFGRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDI--ARYVL-MR 531
           RCSVLAAANSVFGRWD+TK +DNIDFMPTILSRFDMIFIVKDEH++ RD+  A++V+ + 
Sbjct: 481 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH 540

Query: 532 TGALQHERQADKRLSI 547
             AL   +  +  + +
Sbjct: 541 VSALTQTQAVEGEIDL 556



 Score =  237 bits (580), Expect = 9e-62
 Identities = 110/149 (73%), Positives = 137/149 (91%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MR+GA QHER +D+R SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 585 RYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 644

Query: 586 QVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQTIIQDFLRQKYP 645
           QVSTLDAA++G+L+G EGFT++ED EML+R+EKQLKRRFA+GSQVSE +II+DF +QKYP
Sbjct: 645 QVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYP 704

Query: 646 ERAILKVIHMMIRRGELQHRLQRKMLYRL 674
           E AI KV+ +M+RRGE+QHR+QRK+LYRL
Sbjct: 705 EHAIHKVLQLMLRRGEIQHRMQRKVLYRL 733


>AK223323-1|BAD97043.1|  734|Homo sapiens minichromosome maintenance
           deficient protein 5 variant protein.
          Length = 734

 Score =  789 bits (1951), Expect = 0.0
 Identities = 363/556 (65%), Positives = 447/556 (80%), Gaps = 9/556 (1%)

Query: 1   MEGFDDPGVFFSDNFGVEENESQDHVNLQAVKKKFKEFMRQFHTGN----FNYKYRDALK 56
           M GFDDPG+F+SD+FG +    +       ++++FKEF+RQ+  G     F +KYRD LK
Sbjct: 1   MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK 60

Query: 57  RNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEK 116
           R+YNL +YW+E+ +EDL+SFD+ LA+ LYK+P EHL +              PRP GEE 
Sbjct: 61  RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV 120

Query: 117 VEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIP 176
           ++DIQV+L SDA  S++R LKS+ +  LVKIPGI+I+AS ++AKAT+ISIQCRSCRN + 
Sbjct: 121 LQDIQVMLKSDASPSSIRSLKSDMMPHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT 180

Query: 177 NLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGE 236
           N+ ++PGLEGY +PRKCNT+Q+GRPKCPLDPYFI+PDKCKC+D+Q LKLQE P+++P GE
Sbjct: 181 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE 240

Query: 237 MPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLT 296
           MPRH+ +YCDR LC++V PG RVT++GIYSIKK       GRD+  VG+RSSY+R +G+ 
Sbjct: 241 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ 300

Query: 297 AEEGVT--SGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGG 354
            +   +  S     + +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGG
Sbjct: 301 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG 360

Query: 355 SRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIR 414
           SRKRLPDGLTRRGDIN+L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+R
Sbjct: 361 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR 420

Query: 415 DPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 474
           DP SRNF+MEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
Sbjct: 421 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS 480

Query: 475 RCSVLAAANSVFGRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDI--ARYVL-MR 531
           RCSVLAAANSVFGRWD+TK +DNIDFMPTILSRFDMIFIVKDEH++ RD+  A++V+ + 
Sbjct: 481 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH 540

Query: 532 TGALQHERQADKRLSI 547
             AL   +  +  + +
Sbjct: 541 VSALTQTQAVEGEIDL 556



 Score =  234 bits (573), Expect = 6e-61
 Identities = 109/149 (73%), Positives = 136/149 (91%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MR+GA QHER +D+R SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 585 RYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 644

Query: 586 QVSTLDAAMTGSLAGAEGFTTEEDHEMLTRVEKQLKRRFAVGSQVSEQTIIQDFLRQKYP 645
           QVSTLDAA++G+L+G EGFT++ED EML+R+EKQLK RFA+GSQVSE +II+DF +QKYP
Sbjct: 645 QVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKPRFAIGSQVSEHSIIKDFTKQKYP 704

Query: 646 ERAILKVIHMMIRRGELQHRLQRKMLYRL 674
           E AI KV+ +M+RRGE+QHR+QRK+LYRL
Sbjct: 705 EHAIHKVLQLMLRRGEIQHRMQRKVLYRL 733


>AB209612-1|BAD92849.1|  418|Homo sapiens minichromosome maintenance
           deficient protein 5 variant protein.
          Length = 418

 Score =  405 bits (996), Expect = e-112
 Identities = 194/240 (80%), Positives = 217/240 (90%), Gaps = 3/240 (1%)

Query: 311 EEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDIN 370
           +EEE+FRRLAA P++YE I KSIAPS+FG  DMKKAIACLLFGGSRKRLPDGLTRRGDIN
Sbjct: 34  QEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDIN 93

Query: 371 ILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVL 430
           +L+LGDPGTAKSQLLKFVEK +PIGVYTSGKGSSAAGLTASV+RDP SRNF+MEGGAMVL
Sbjct: 94  LLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVL 153

Query: 431 ADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWD 490
           ADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWD
Sbjct: 154 ADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWD 213

Query: 491 DTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDI--ARYVL-MRTGALQHERQADKRLSI 547
           +TK +DNIDFMPTILSRFDMIFIVKDEH++ RD+  A++V+ +   AL   +  +  + +
Sbjct: 214 ETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDL 273



 Score =  121 bits (291), Expect = 1e-26
 Identities = 57/77 (74%), Positives = 71/77 (92%)

Query: 526 RYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLF 585
           RY++MR+GA QHER +D+R SIPITVRQLEAIVRI+E+L+KM+LQPFATEA V EALRLF
Sbjct: 302 RYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLF 361

Query: 586 QVSTLDAAMTGSLAGAE 602
           QVSTLDAA++G+L+G +
Sbjct: 362 QVSTLDAALSGTLSGEQ 378


>X74796-1|CAA52803.1|  617|Homo sapiens p85Mcm protein protein.
          Length = 617

 Score =  290 bits (711), Expect = 1e-77
 Identities = 177/455 (38%), Positives = 257/455 (56%), Gaps = 26/455 (5%)

Query: 133 LRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVM--P 190
           +RE+++++V +LV + GIV   S +K K    +  C  C          P     +M   
Sbjct: 47  IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 106

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLC 250
           ++C T +SG         ++     + I +Q +K+QE  + +P G +PR +TV  +    
Sbjct: 107 QECQTNRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENT 160

Query: 251 ERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRA---VGLTAEEGVTSGLRP 307
               PG  V+V GI+    I + G     +G +    +YL A   V +   E   SG   
Sbjct: 161 RIAQPGDHVSVTGIFL--PILRTGFRQVVQGLLS--ETYLEAHRIVKMNKSEDDESGAGE 216

Query: 308 FTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRG 367
            T EE  Q     A  D YE++  SIAP ++G  D+KKA+  LL GG  +  P G+  RG
Sbjct: 217 LTREELRQI----AEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRG 271

Query: 368 DINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGA 427
           +INI L+GDPG AKSQLL +++++AP   YT+G+GSS  GLTA+V+RD  S    +EGGA
Sbjct: 272 NINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGA 331

Query: 428 MVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 487
           +VLAD GV CIDEFDKM E DR AIHE MEQQTISIAKAGI TTLN+RCS+LAAAN  +G
Sbjct: 332 LVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 391

Query: 488 RWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLS 546
           R++  ++ + NI     +LSRFD++++++D  D++ D+ R     T   QH RQ   +  
Sbjct: 392 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDL-RLAQHITYVHQHSRQPPSQFE 450

Query: 547 IPI---TVRQLEAIVRISESLAKMQLQPFATEAHV 578
            P+    +R+  A+ R  + +    L  + T A+V
Sbjct: 451 -PLDMKLMRRYIAMCREKQPMVPESLADYITAAYV 484



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%)

Query: 524 IARYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALR 583
           +A Y+      ++ E  A K  +   + R L AI+R+S +LA++++     +  VNEA+R
Sbjct: 475 LADYITAAYVEMRREAWASKDATYT-SARTLLAILRLSTALARLRMVDVVEKEDVNEAIR 533

Query: 584 LFQVS 588
           L ++S
Sbjct: 534 LMEMS 538


>D55716-1|BAA09534.1|  719|Homo sapiens P1cdc47 protein.
          Length = 719

 Score =  290 bits (711), Expect = 1e-77
 Identities = 177/455 (38%), Positives = 257/455 (56%), Gaps = 26/455 (5%)

Query: 133 LRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVM--P 190
           +RE+++++V +LV + GIV   S +K K    +  C  C          P     +M   
Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLC 250
           ++C T +SG         ++     + I +Q +K+QE  + +P G +PR +TV  +    
Sbjct: 209 QECQTNRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENT 262

Query: 251 ERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRA---VGLTAEEGVTSGLRP 307
               PG  V+V GI+    I + G     +G +    +YL A   V +   E   SG   
Sbjct: 263 RIAQPGDHVSVTGIFL--PILRTGFRQVVQGLLS--ETYLEAHRIVKMNKSEDDESGAGE 318

Query: 308 FTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRG 367
            T EE  Q     A  D YE++  SIAP ++G  D+KKA+  LL GG  +  P G+  RG
Sbjct: 319 LTREELRQI----AEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRG 373

Query: 368 DINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGA 427
           +INI L+GDPG AKSQLL +++++AP   YT+G+GSS  GLTA+V+RD  S    +EGGA
Sbjct: 374 NINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGA 433

Query: 428 MVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 487
           +VLAD GV CIDEFDKM E DR AIHE MEQQTISIAKAGI TTLN+RCS+LAAAN  +G
Sbjct: 434 LVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 493

Query: 488 RWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLS 546
           R++  ++ + NI     +LSRFD++++++D  D++ D+ R     T   QH RQ   +  
Sbjct: 494 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDL-RLAQHITYVHQHSRQPPSQFE 552

Query: 547 IPI---TVRQLEAIVRISESLAKMQLQPFATEAHV 578
            P+    +R+  A+ R  + +    L  + T A+V
Sbjct: 553 -PLDMKLMRRYIAMCREKQPMVPESLADYITAAYV 586



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%)

Query: 524 IARYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALR 583
           +A Y+      ++ E  A K  +   + R L AI+R+S +LA++++     +  VNEA+R
Sbjct: 577 LADYITAAYVEMRREAWASKDATYT-SARTLLAILRLSTALARLRMVDVVEKEDVNEAIR 635

Query: 584 LFQVS 588
           L ++S
Sbjct: 636 LMEMS 640


>BC013375-1|AAH13375.1|  719|Homo sapiens minichromosome maintenance
           complex component 7 protein.
          Length = 719

 Score =  290 bits (711), Expect = 1e-77
 Identities = 177/455 (38%), Positives = 257/455 (56%), Gaps = 26/455 (5%)

Query: 133 LRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVM--P 190
           +RE+++++V +LV + GIV   S +K K    +  C  C          P     +M   
Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLC 250
           ++C T +SG         ++     + I +Q +K+QE  + +P G +PR +TV  +    
Sbjct: 209 QECQTNRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENT 262

Query: 251 ERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRA---VGLTAEEGVTSGLRP 307
               PG  V+V GI+    I + G     +G +    +YL A   V +   E   SG   
Sbjct: 263 RIAQPGDHVSVTGIFL--PILRTGFRQVVQGLLS--ETYLEAHRIVKMNKSEDDESGAGE 318

Query: 308 FTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRG 367
            T EE  Q     A  D YE++  SIAP ++G  D+KKA+  LL GG  +  P G+  RG
Sbjct: 319 LTREELRQI----AEEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRG 373

Query: 368 DINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGA 427
           +INI L+GDPG AKSQLL +++++AP   YT+G+GSS  GLTA+V+RD  S    +EGGA
Sbjct: 374 NINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGA 433

Query: 428 MVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFG 487
           +VLAD GV CIDEFDKM E DR AIHE MEQQTISIAKAGI TTLN+RCS+LAAAN  +G
Sbjct: 434 LVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 493

Query: 488 RWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLS 546
           R++  ++ + NI     +LSRFD++++++D  D++ D+ R     T   QH RQ   +  
Sbjct: 494 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDL-RLAQHITYVHQHSRQPPSQFE 552

Query: 547 IPI---TVRQLEAIVRISESLAKMQLQPFATEAHV 578
            P+    +R+  A+ R  + +    L  + T A+V
Sbjct: 553 -PLDMKLMRRYIAMCREKQPMVPESLADYITAAYV 586



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%)

Query: 524 IARYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALR 583
           +A Y+      ++ E  A K  +   + R L AI+R+S +LA++++     +  VNEA+R
Sbjct: 577 LADYITAAYVEMRREAWASKDATYT-SARTLLAILRLSTALARLRMVDVVEKEDVNEAIR 635

Query: 584 LFQVS 588
           L ++S
Sbjct: 636 LMEMS 640


>X74794-1|CAA52801.1|  923|Homo sapiens P1 Cdc21 protein protein.
          Length = 923

 Score =  284 bits (697), Expect = 6e-76
 Identities = 189/540 (35%), Positives = 282/540 (52%), Gaps = 35/540 (6%)

Query: 26  VNLQAVKKKFKEFMRQF------HTGNFNYKYRDAL--KRNYNLN---QYWVEINIEDLS 74
           VN+ A K+ F+ F+++F         N      + L  +R   +N   + ++ +N E + 
Sbjct: 217 VNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEQFLNVNCEHIK 276

Query: 75  SFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLR 134
           SFD  L  +L   P E +P                R         IQV   +   + N+R
Sbjct: 277 SFDKNLYRQLISYPQEVIP----TFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMR 332

Query: 135 ELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCN 194
            L  E + +L+ I G+VI  S +  +  +   QC+ C +       +  +    +  +C+
Sbjct: 333 NLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCH 392

Query: 195 TEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVA 254
           T  S           +I ++    D Q++KLQE+PE +P G+ P  + ++    L ++V 
Sbjct: 393 TTHS---------MALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQ 443

Query: 255 PGARVTVLGIYSIKKIAKVGREGRDKG--SVGVRSSYLRAVGLTAEEGVTSGLRP--FTA 310
           PG RV V GIY    I    R    K      +   + R        G+        F+ 
Sbjct: 444 PGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSE 503

Query: 311 EEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPD-GLTR-RGD 368
           +  E  + L+  PDIYER+  ++APS++   D+KK I   LFGG+RK     G  + R +
Sbjct: 504 KRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAE 563

Query: 369 INILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAM 428
           INILL GDPGT+KSQLL++V  + P G YTSGKGSSA GLTA V++DP +R  V++ GA+
Sbjct: 564 INILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGAL 623

Query: 429 VLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGR 488
           VL+D G+ CIDEFDKM E  R  +HE MEQQT+SIAKAGI   LN+R SVLAAAN +  +
Sbjct: 624 VLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQ 683

Query: 489 WDDTKAD-DNIDFMPTILSRFDMIFIVKDEHDQ--NRDIARYVLMRTGALQHERQADKRL 545
           W+  K   +NI    T+LSRFD+IF++ D  D+  +R +A +++      Q E QA++ L
Sbjct: 684 WNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVAL--YYQSEEQAEEEL 741


>U63630-1|AAC52018.1|  712|Homo sapiens MCM4 protein.
          Length = 712

 Score =  283 bits (695), Expect = 1e-75
 Identities = 189/540 (35%), Positives = 282/540 (52%), Gaps = 35/540 (6%)

Query: 26  VNLQAVKKKFKEFMRQF------HTGNFNYKYRDAL--KRNYNLN---QYWVEINIEDLS 74
           VN+ A K+ F+ F+++F         N      + L  +R   +N   + ++ +N E + 
Sbjct: 157 VNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIK 216

Query: 75  SFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLR 134
           SFD  L  +L   P E +P                R         IQV   +   + N+R
Sbjct: 217 SFDKNLYRQLISYPQEVIP----TFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMR 272

Query: 135 ELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCN 194
            L  E + +L+ I G+VI  S +  +  +   QC+ C +       +  +    +  +C+
Sbjct: 273 NLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCH 332

Query: 195 TEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVA 254
           T  S           +I ++    D Q++KLQE+PE +P G+ P  + ++    L ++V 
Sbjct: 333 TTHS---------MALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQ 383

Query: 255 PGARVTVLGIYSIKKIAKVGREGRDKG--SVGVRSSYLRAVGLTAEEGVTSGLRP--FTA 310
           PG RV V GIY    I    R    K      +   + R        G+        F+ 
Sbjct: 384 PGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSE 443

Query: 311 EEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPD-GLTR-RGD 368
           +  E  + L+  PDIYER+  ++APS++   D+KK I   LFGG+RK     G  + R +
Sbjct: 444 KRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAE 503

Query: 369 INILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAM 428
           INILL GDPGT+KSQLL++V  + P G YTSGKGSSA GLTA V++DP +R  V++ GA+
Sbjct: 504 INILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGAL 563

Query: 429 VLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGR 488
           VL+D G+ CIDEFDKM E  R  +HE MEQQT+SIAKAGI   LN+R SVLAAAN +  +
Sbjct: 564 VLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQ 623

Query: 489 WDDTKAD-DNIDFMPTILSRFDMIFIVKDEHDQ--NRDIARYVLMRTGALQHERQADKRL 545
           W+  K   +NI    T+LSRFD+IF++ D  D+  +R +A +++      Q E QA++ L
Sbjct: 624 WNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVAL--YYQSEEQAEEEL 681


>BC031061-1|AAH31061.1|  863|Homo sapiens minichromosome maintenance
           complex component 4 protein.
          Length = 863

 Score =  283 bits (695), Expect = 1e-75
 Identities = 189/540 (35%), Positives = 282/540 (52%), Gaps = 35/540 (6%)

Query: 26  VNLQAVKKKFKEFMRQF------HTGNFNYKYRDAL--KRNYNLN---QYWVEINIEDLS 74
           VN+ A K+ F+ F+++F         N      + L  +R   +N   + ++ +N E + 
Sbjct: 157 VNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIK 216

Query: 75  SFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLR 134
           SFD  L  +L   P E +P                R         IQV   +   + N+R
Sbjct: 217 SFDKNLYRQLISYPQEVIP----TFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMR 272

Query: 135 ELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCN 194
            L  E + +L+ I G+VI  S +  +  +   QC+ C +       +  +    +  +C+
Sbjct: 273 NLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCH 332

Query: 195 TEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVA 254
           T  S           +I ++    D Q++KLQE+PE +P G+ P  + ++    L ++V 
Sbjct: 333 TTHS---------MALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQ 383

Query: 255 PGARVTVLGIYSIKKIAKVGREGRDKG--SVGVRSSYLRAVGLTAEEGVTSGLRP--FTA 310
           PG RV V GIY    I    R    K      +   + R        G+        F+ 
Sbjct: 384 PGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSE 443

Query: 311 EEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPD-GLTR-RGD 368
           +  E  + L+  PDIYER+  ++APS++   D+KK I   LFGG+RK     G  + R +
Sbjct: 444 KRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAE 503

Query: 369 INILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAM 428
           INILL GDPGT+KSQLL++V  + P G YTSGKGSSA GLTA V++DP +R  V++ GA+
Sbjct: 504 INILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGAL 563

Query: 429 VLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGR 488
           VL+D G+ CIDEFDKM E  R  +HE MEQQT+SIAKAGI   LN+R SVLAAAN +  +
Sbjct: 564 VLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQ 623

Query: 489 WDDTKAD-DNIDFMPTILSRFDMIFIVKDEHDQ--NRDIARYVLMRTGALQHERQADKRL 545
           W+  K   +NI    T+LSRFD+IF++ D  D+  +R +A +++      Q E QA++ L
Sbjct: 624 WNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVAL--YYQSEEQAEEEL 681


>AY588245-1|AAS83108.1|  863|Homo sapiens MCM4 minichromosome
           maintenance deficient 4 (S. cerevisiae) protein.
          Length = 863

 Score =  283 bits (695), Expect = 1e-75
 Identities = 189/540 (35%), Positives = 282/540 (52%), Gaps = 35/540 (6%)

Query: 26  VNLQAVKKKFKEFMRQF------HTGNFNYKYRDAL--KRNYNLN---QYWVEINIEDLS 74
           VN+ A K+ F+ F+++F         N      + L  +R   +N   + ++ +N E + 
Sbjct: 157 VNVAACKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIK 216

Query: 75  SFDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLR 134
           SFD  L  +L   P E +P                R         IQV   +   + N+R
Sbjct: 217 SFDKNLYRQLISYPQEVIP----TFDMAVNEIFFDRYPDSILEHQIQVRPFNALKTKNMR 272

Query: 135 ELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCN 194
            L  E + +L+ I G+VI  S +  +  +   QC+ C +       +  +    +  +C+
Sbjct: 273 NLNPEDIDQLITISGMVIRTSQLIPEMQEAFFQCQVCAHTTRVEMDRGRIAEPSVCGRCH 332

Query: 195 TEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVA 254
           T  S           +I ++    D Q++KLQE+PE +P G+ P  + ++    L ++V 
Sbjct: 333 TTHS---------MALIHNRSLFSDKQMIKLQESPEDMPAGQTPHTVILFAHNDLVDKVQ 383

Query: 255 PGARVTVLGIYSIKKIAKVGREGRDKG--SVGVRSSYLRAVGLTAEEGVTSGLRP--FTA 310
           PG RV V GIY    I    R    K      +   + R        G+        F+ 
Sbjct: 384 PGDRVNVTGIYRAVPIRVNPRVSNVKSVYKTHIDVIHYRKTDAKRLHGLDEEAEQKLFSE 443

Query: 311 EEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPD-GLTR-RGD 368
           +  E  + L+  PDIYER+  ++APS++   D+KK I   LFGG+RK     G  + R +
Sbjct: 444 KRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAE 503

Query: 369 INILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAM 428
           INILL GDPGT+KSQLL++V  + P G YTSGKGSSA GLTA V++DP +R  V++ GA+
Sbjct: 504 INILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGAL 563

Query: 429 VLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGR 488
           VL+D G+ CIDEFDKM E  R  +HE MEQQT+SIAKAGI   LN+R SVLAAAN +  +
Sbjct: 564 VLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQ 623

Query: 489 WDDTKAD-DNIDFMPTILSRFDMIFIVKDEHDQ--NRDIARYVLMRTGALQHERQADKRL 545
           W+  K   +NI    T+LSRFD+IF++ D  D+  +R +A +++      Q E QA++ L
Sbjct: 624 WNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVAL--YYQSEEQAEEEL 681


>D21063-1|BAA04642.1|  914|Homo sapiens KIAA0030 protein.
          Length = 914

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 205 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 264

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 265 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 321

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 322 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 373

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 374 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 433

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 434 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 488

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 489 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 547

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 548 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 607

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 608 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 667

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 668 DILCVVRDTVDPVQDEMLARFVV 690



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 769 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 814


>BT009734-1|AAP88736.1|  895|Homo sapiens MCM2 minichromosome
           maintenance deficient 2, mitotin (S. cerevisiae)
           protein.
          Length = 895

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 186 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 245

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 246 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 302

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 303 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 354

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 355 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 414

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 415 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 469

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 470 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 528

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 529 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 588

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 589 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 648

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 649 DILCVVRDTVDPVQDEMLARFVV 671



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 750 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 795


>BC030131-1|AAH30131.2|  808|Homo sapiens MCM2 protein protein.
          Length = 808

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 99  IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 158

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 159 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 215

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 216 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 267

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 268 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 327

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 328 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 382

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 383 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 441

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 442 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 501

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 502 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 561

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 562 DILCVVRDTVDPVQDEMLARFVV 584



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 663 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 708


>BC017490-1|AAH17490.2|  904|Homo sapiens minichromosome maintenance
           complex component 2 protein.
          Length = 904

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 254

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 255 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 363

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 364 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 423

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 424 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 478

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 479 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 537

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 538 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 597

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 598 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 657

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 658 DILCVVRDTVDPVQDEMLARFVV 680



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 759 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 804


>BC014272-1|AAH14272.2|  904|Homo sapiens minichromosome maintenance
           complex component 2 protein.
          Length = 904

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 254

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 255 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 363

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 364 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 423

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 424 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 478

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 479 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 537

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 538 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 597

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 598 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 657

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 658 DILCVVRDTVDPVQDEMLARFVV 680



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 759 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 804


>BC007938-1|AAH07938.2|  904|Homo sapiens minichromosome maintenance
           complex component 2 protein.
          Length = 904

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 254

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 255 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 363

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 364 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 423

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 424 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 478

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 479 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 537

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 538 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 597

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 598 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 657

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 658 DILCVVRDTVDPVQDEMLARFVV 680



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 759 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 804


>BC007670-1|AAH07670.2|  904|Homo sapiens minichromosome maintenance
           complex component 2 protein.
          Length = 904

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 254

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 255 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 363

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 364 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 423

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 424 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 478

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 479 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 537

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 538 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 597

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 598 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 657

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 658 DILCVVRDTVDPVQDEMLARFVV 680



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 759 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 804


>BC006165-1|AAH06165.3|  904|Homo sapiens minichromosome maintenance
           complex component 2 protein.
          Length = 904

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 254

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 255 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 363

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 364 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 423

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 424 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 478

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 479 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 537

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 538 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 597

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 598 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 657

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 658 DILCVVRDTVDPVQDEMLARFVV 680



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 759 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 804


>AY675259-1|AAT70723.1|  904|Homo sapiens MCM2 minichromosome
           maintenance deficient 2, mitotin (S. cerevisiae)
           protein.
          Length = 904

 Score =  273 bits (670), Expect = 1e-72
 Identities = 171/503 (33%), Positives = 270/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 254

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 255 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 363

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 364 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 423

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 424 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 478

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 479 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 537

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 538 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 597

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 598 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 657

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 658 DILCVVRDTVDPVQDEMLARFVV 680



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 759 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 804


>D28480-1|BAA05839.1|  543|Homo sapiens hMCM2 protein.
          Length = 543

 Score =  272 bits (667), Expect = 3e-72
 Identities = 158/368 (42%), Positives = 221/368 (60%), Gaps = 18/368 (4%)

Query: 218 IDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGREG 277
           I +Q +K+QE  + +P G +PR +TV  +        PG  V+V GI+    I + G   
Sbjct: 54  IKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFL--PILRTGFRQ 111

Query: 278 RDKGSVGVRSSYLRA---VGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIGKSIA 334
             +G +    +YL A   V +   E   SG    T EE  Q     A  D YE++  SIA
Sbjct: 112 VVQGLLS--ETYLEAHRIVKMNKSEDDESGAGELTREELRQI----AEEDFYEKLAASIA 165

Query: 335 PSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPI 394
           P ++G  D+KKA+  LL GG  +  P G+  RG+INI L+GDPG AKSQLL +++++AP 
Sbjct: 166 PEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPR 224

Query: 395 GVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHE 454
             YT+G+GSS  GLTA+V+RD  S    +EGGA+VLAD GV CIDEFDKM E DR AIHE
Sbjct: 225 SQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHE 284

Query: 455 AMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRFDMIFI 513
            MEQQTISIAKAGI TTLN+RCS+LAAAN  +GR++  ++ + NI     +LSRFD++++
Sbjct: 285 VMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWL 344

Query: 514 VKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPI---TVRQLEAIVRISESLAKMQLQ 570
           ++D  D++ D+ R     T   QH RQ   +   P+    +R+  A+ R  + +    L 
Sbjct: 345 IQDRPDRDNDL-RLAQHITYVHQHSRQPPSQFE-PLDMKLMRRYIAMCREKQPMVPESLA 402

Query: 571 PFATEAHV 578
            + T A+V
Sbjct: 403 DYITAAYV 410



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%)

Query: 524 IARYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALR 583
           +A Y+      ++ E  A K  +   + R L AI+R+S +LA++++     +  VNEA+R
Sbjct: 401 LADYITAAYVEMRREAWASKDATYT-SARTLLAILRLSTALARLRMVDVVEKEDVNEAIR 459

Query: 584 LFQVS 588
           L ++S
Sbjct: 460 LMEMS 464


>BC017258-1|AAH17258.2|  904|Homo sapiens minichromosome maintenance
           complex component 2 protein.
          Length = 904

 Score =  270 bits (662), Expect = 1e-71
 Identities = 170/503 (33%), Positives = 269/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 195 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 254

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 255 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 311

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 312 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 363

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +   PG  + + GIY     
Sbjct: 364 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYD 423

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 424 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 478

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LF G  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 479 ASIAPSIYGHEDIKRGLALALFRGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 537

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 538 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 597

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 598 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 657

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 658 DILCVVRDTVDPVQDEMLARFVV 680



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 759 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 804


>D83987-1|BAA12177.1|  895|Homo sapiens huMCM2 protein.
          Length = 895

 Score =  270 bits (661), Expect = 1e-71
 Identities = 170/503 (33%), Positives = 269/503 (53%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 186 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 245

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 246 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 302

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 303 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 354

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +  G +PR         L +    G  + + GIY     
Sbjct: 355 NMEETIYQNYQRIRIQESPGKVAAGRLPRSKDAILLADLVDSCNAGDEIELTGIYHNNYD 414

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 415 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 469

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+ +A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 470 ASIAPSIYGHEDIKRGLALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 528

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 529 KVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 588

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 589 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 648

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 649 DILCVVRDTVDPVQDEMLARFVV 671



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 750 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 795


>X62153-1|CAA44078.2|  808|Homo sapiens P1.h protein protein.
          Length = 808

 Score =  266 bits (652), Expect = 2e-70
 Identities = 185/517 (35%), Positives = 274/517 (52%), Gaps = 33/517 (6%)

Query: 24  DHVNLQAVKKKFKEFMR-QFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAE 82
           D V L+  ++ + +F+  +   G +  K R+ +  N    QY + +N+ DL   ++  A 
Sbjct: 8   DDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDN----QYRLIVNVNDLRRKNEKRAN 63

Query: 83  KLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNL--RELKSET 140
           +L     E L                   +   + E+  V L     S ++  R L S  
Sbjct: 64  RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 141 VSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYV-MPRKCNTEQSG 199
           +S +V + GIV   S ++ K  +    C + +  I        L   V  P         
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR--YSDLTTLVAFPSSSVYPTKD 178

Query: 200 RPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARV 259
               PL+  + +       D+Q + +QE PE  P G++PR + V  D  L ++  PG RV
Sbjct: 179 EENNPLETEYGLS---VYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRV 235

Query: 260 TVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAE-EGVTSGLRP-FTAEEEEQFR 317
            V+G Y        G++G      G  S   R V +    + ++   +P F+AE+  + +
Sbjct: 236 QVVGTYRCLP----GKKG------GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIK 285

Query: 318 RLAA--SPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLG 375
           + +   S DI++++ KS+APS+ G   +KKAI CLL GG  + L +G   RGDINILL+G
Sbjct: 286 KFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345

Query: 376 DPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGV 435
           DP  AKSQLL++V   AP  + T+G+GSS  GLTA+V  D  +    +E GAMVLAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405

Query: 436 VCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKAD 495
           VCIDEFDKM + DR AIHE MEQ  ++IAKAGI   LN+RCSVLAAAN V+GR+D  K  
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465

Query: 496 -DNIDFMPTILSRFDMIFIVKDEHD--QNRDIARYVL 529
            +NI    ++LSRFD++FI+ D+ D  Q+R+I+ +VL
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 502


>BC003509-1|AAH03509.2|  808|Homo sapiens minichromosome maintenance
           complex component 3 protein.
          Length = 808

 Score =  266 bits (652), Expect = 2e-70
 Identities = 185/517 (35%), Positives = 274/517 (52%), Gaps = 33/517 (6%)

Query: 24  DHVNLQAVKKKFKEFMR-QFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAE 82
           D V L+  ++ + +F+  +   G +  K R+ +  N    QY + +N+ DL   ++  A 
Sbjct: 8   DDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDN----QYRLIVNVNDLRRKNEKRAN 63

Query: 83  KLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNL--RELKSET 140
           +L     E L                   +   + E+  V L     S ++  R L S  
Sbjct: 64  RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 141 VSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYV-MPRKCNTEQSG 199
           +S +V + GIV   S ++ K  +    C + +  I        L   V  P         
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR--YSDLTTLVAFPSSSVYPTKD 178

Query: 200 RPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARV 259
               PL+  + +       D+Q + +QE PE  P G++PR + V  D  L ++  PG RV
Sbjct: 179 EENNPLETEYGLS---VYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRV 235

Query: 260 TVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAE-EGVTSGLRP-FTAEEEEQFR 317
            V+G Y        G++G      G  S   R V +    + ++   +P F+AE+  + +
Sbjct: 236 QVVGTYRCLP----GKKG------GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIK 285

Query: 318 RLAA--SPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLG 375
           + +   S DI++++ KS+APS+ G   +KKAI CLL GG  + L +G   RGDINILL+G
Sbjct: 286 KFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345

Query: 376 DPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGV 435
           DP  AKSQLL++V   AP  + T+G+GSS  GLTA+V  D  +    +E GAMVLAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405

Query: 436 VCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKAD 495
           VCIDEFDKM + DR AIHE MEQ  ++IAKAGI   LN+RCSVLAAAN V+GR+D  K  
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465

Query: 496 -DNIDFMPTILSRFDMIFIVKDEHD--QNRDIARYVL 529
            +NI    ++LSRFD++FI+ D+ D  Q+R+I+ +VL
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 502


>BC001626-1|AAH01626.1|  808|Homo sapiens minichromosome maintenance
           complex component 3 protein.
          Length = 808

 Score =  266 bits (652), Expect = 2e-70
 Identities = 185/517 (35%), Positives = 274/517 (52%), Gaps = 33/517 (6%)

Query: 24  DHVNLQAVKKKFKEFMR-QFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAE 82
           D V L+  ++ + +F+  +   G +  K R+ +  N    QY + +N+ DL   ++  A 
Sbjct: 8   DDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDN----QYRLIVNVNDLRRKNEKRAN 63

Query: 83  KLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNL--RELKSET 140
           +L     E L                   +   + E+  V L     S ++  R L S  
Sbjct: 64  RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 141 VSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYV-MPRKCNTEQSG 199
           +S +V + GIV   S ++ K  +    C + +  I        L   V  P         
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR--YSDLTTLVAFPSSSVYPTKD 178

Query: 200 RPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARV 259
               PL+  + +       D+Q + +QE PE  P G++PR + V  D  L ++  PG RV
Sbjct: 179 EENNPLETEYGLS---VYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRV 235

Query: 260 TVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAE-EGVTSGLRP-FTAEEEEQFR 317
            V+G Y        G++G      G  S   R V +    + ++   +P F+AE+  + +
Sbjct: 236 QVVGTYRCLP----GKKG------GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIK 285

Query: 318 RLAA--SPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLG 375
           + +   S DI++++ KS+APS+ G   +KKAI CLL GG  + L +G   RGDINILL+G
Sbjct: 286 KFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345

Query: 376 DPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGV 435
           DP  AKSQLL++V   AP  + T+G+GSS  GLTA+V  D  +    +E GAMVLAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405

Query: 436 VCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKAD 495
           VCIDEFDKM + DR AIHE MEQ  ++IAKAGI   LN+RCSVLAAAN V+GR+D  K  
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465

Query: 496 -DNIDFMPTILSRFDMIFIVKDEHD--QNRDIARYVL 529
            +NI    ++LSRFD++FI+ D+ D  Q+R+I+ +VL
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 502


>AY621074-1|AAT27321.1|  808|Homo sapiens MCM3 minichromosome
           maintenance deficient 3 (S. cerevisiae) protein.
          Length = 808

 Score =  266 bits (652), Expect = 2e-70
 Identities = 185/517 (35%), Positives = 274/517 (52%), Gaps = 33/517 (6%)

Query: 24  DHVNLQAVKKKFKEFMR-QFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAE 82
           D V L+  ++ + +F+  +   G +  K R+ +  N    QY + +N+ DL   ++  A 
Sbjct: 8   DDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDN----QYRLIVNVNDLRRKNEKRAN 63

Query: 83  KLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNL--RELKSET 140
           +L     E L                   +   + E+  V L     S ++  R L S  
Sbjct: 64  RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 141 VSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYV-MPRKCNTEQSG 199
           +S +V + GIV   S ++ K  +    C + +  I        L   V  P         
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR--YSDLTTLVAFPSSSVYPTKD 178

Query: 200 RPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARV 259
               PL+  + +       D+Q + +QE PE  P G++PR + V  D  L ++  PG RV
Sbjct: 179 EENNPLETEYGLS---VYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRV 235

Query: 260 TVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAE-EGVTSGLRP-FTAEEEEQFR 317
            V+G Y        G++G      G  S   R V +    + ++   +P F+AE+  + +
Sbjct: 236 QVVGTYRCLP----GKKG------GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIK 285

Query: 318 RLAA--SPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLG 375
           + +   S DI++++ KS+APS+ G   +KKAI CLL GG  + L +G   RGDINILL+G
Sbjct: 286 KFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345

Query: 376 DPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGV 435
           DP  AKSQLL++V   AP  + T+G+GSS  GLTA+V  D  +    +E GAMVLAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405

Query: 436 VCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKAD 495
           VCIDEFDKM + DR AIHE MEQ  ++IAKAGI   LN+RCSVLAAAN V+GR+D  K  
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465

Query: 496 -DNIDFMPTILSRFDMIFIVKDEHD--QNRDIARYVL 529
            +NI    ++LSRFD++FI+ D+ D  Q+R+I+ +VL
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 502


>AY032603-1|AAK56392.1|  676|Homo sapiens cervical cancer
           proto-oncogene 5 protein.
          Length = 676

 Score =  266 bits (652), Expect = 2e-70
 Identities = 185/517 (35%), Positives = 274/517 (52%), Gaps = 33/517 (6%)

Query: 24  DHVNLQAVKKKFKEFMR-QFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAE 82
           D V L+  ++ + +F+  +   G +  K R+ +  N    QY + +N+ DL   ++  A 
Sbjct: 8   DDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDN----QYRLIVNVNDLRRKNEKRAN 63

Query: 83  KLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNL--RELKSET 140
           +L     E L                   +   + E+  V L     S ++  R L S  
Sbjct: 64  RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 141 VSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYV-MPRKCNTEQSG 199
           +S +V + GIV   S ++ K  +    C + +  I        L   V  P         
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR--YSDLTTLVAFPSSSVYPTKD 178

Query: 200 RPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARV 259
               PL+  + +       D+Q + +QE PE  P G++PR + V  D  L ++  PG RV
Sbjct: 179 EENNPLETEYGLS---VYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRV 235

Query: 260 TVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAE-EGVTSGLRP-FTAEEEEQFR 317
            V+G Y        G++G      G  S   R V +    + ++   +P F+AE+  + +
Sbjct: 236 QVVGTYRCLP----GKKG------GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIK 285

Query: 318 RLAA--SPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLG 375
           + +   S DI++++ KS+APS+ G   +KKAI CLL GG  + L +G   RGDINILL+G
Sbjct: 286 KFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345

Query: 376 DPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGV 435
           DP  AKSQLL++V   AP  + T+G+GSS  GLTA+V  D  +    +E GAMVLAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405

Query: 436 VCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKAD 495
           VCIDEFDKM + DR AIHE MEQ  ++IAKAGI   LN+RCSVLAAAN V+GR+D  K  
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465

Query: 496 -DNIDFMPTILSRFDMIFIVKDEHD--QNRDIARYVL 529
            +NI    ++LSRFD++FI+ D+ D  Q+R+I+ +VL
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 502


>AL034343-1|CAB75298.1|  808|Homo sapiens MCM3 minichromosome
           maintenance deficient 3 (S. cerevisiae) protein.
          Length = 808

 Score =  266 bits (652), Expect = 2e-70
 Identities = 185/517 (35%), Positives = 274/517 (52%), Gaps = 33/517 (6%)

Query: 24  DHVNLQAVKKKFKEFMR-QFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAE 82
           D V L+  ++ + +F+  +   G +  K R+ +  N    QY + +N+ DL   ++  A 
Sbjct: 8   DDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDN----QYRLIVNVNDLRRKNEKRAN 63

Query: 83  KLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNL--RELKSET 140
           +L     E L                   +   + E+  V L     S ++  R L S  
Sbjct: 64  RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 141 VSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYV-MPRKCNTEQSG 199
           +S +V + GIV   S ++ K  +    C + +  I        L   V  P         
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR--YSDLTTLVAFPSSSVYPTKD 178

Query: 200 RPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARV 259
               PL+  + +       D+Q + +QE PE  P G++PR + V  D  L ++  PG RV
Sbjct: 179 EENNPLETEYGLS---VYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRV 235

Query: 260 TVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAE-EGVTSGLRP-FTAEEEEQFR 317
            V+G Y        G++G      G  S   R V +    + ++   +P F+AE+  + +
Sbjct: 236 QVVGTYRCLP----GKKG------GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIK 285

Query: 318 RLAA--SPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLG 375
           + +   S DI++++ KS+APS+ G   +KKAI CLL GG  + L +G   RGDINILL+G
Sbjct: 286 KFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345

Query: 376 DPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGV 435
           DP  AKSQLL++V   AP  + T+G+GSS  GLTA+V  D  +    +E GAMVLAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405

Query: 436 VCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKAD 495
           VCIDEFDKM + DR AIHE MEQ  ++IAKAGI   LN+RCSVLAAAN V+GR+D  K  
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465

Query: 496 -DNIDFMPTILSRFDMIFIVKDEHD--QNRDIARYVL 529
            +NI    ++LSRFD++FI+ D+ D  Q+R+I+ +VL
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 502


>AK222586-1|BAD96306.1|  808|Homo sapiens minichromosome maintenance
           protein 3 variant protein.
          Length = 808

 Score =  266 bits (652), Expect = 2e-70
 Identities = 185/517 (35%), Positives = 274/517 (52%), Gaps = 33/517 (6%)

Query: 24  DHVNLQAVKKKFKEFMR-QFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAE 82
           D V L+  ++ + +F+  +   G +  K R+ +  N    QY + +N+ DL   ++  A 
Sbjct: 8   DDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDN----QYRLIVNVNDLRRKNEKRAN 63

Query: 83  KLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNL--RELKSET 140
           +L     E L                   +   + E+  V L     S ++  R L S  
Sbjct: 64  RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 141 VSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYV-MPRKCNTEQSG 199
           +S +V + GIV   S ++ K  +    C + +  I        L   V  P         
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR--YSDLTTLVAFPSSSVYPTKD 178

Query: 200 RPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARV 259
               PL+  + +       D+Q + +QE PE  P G++PR + V  D  L ++  PG RV
Sbjct: 179 EENNPLETEYGLS---VYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRV 235

Query: 260 TVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAE-EGVTSGLRP-FTAEEEEQFR 317
            V+G Y        G++G      G  S   R V +    + ++   +P F+AE+  + +
Sbjct: 236 QVVGTYRCLP----GKKG------GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIK 285

Query: 318 RLAA--SPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLG 375
           + +   S DI++++ KS+APS+ G   +KKAI CLL GG  + L +G   RGDINILL+G
Sbjct: 286 KFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345

Query: 376 DPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGV 435
           DP  AKSQLL++V   AP  + T+G+GSS  GLTA+V  D  +    +E GAMVLAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405

Query: 436 VCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKAD 495
           VCIDEFDKM + DR AIHE MEQ  ++IAKAGI   LN+RCSVLAAAN V+GR+D  K  
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465

Query: 496 -DNIDFMPTILSRFDMIFIVKDEHD--QNRDIARYVL 529
            +NI    ++LSRFD++FI+ D+ D  Q+R+I+ +VL
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 502


>D38073-1|BAA07267.1|  808|Homo sapiens hRlf beta subunit (p102
           protein) protein.
          Length = 808

 Score =  262 bits (643), Expect = 2e-69
 Identities = 184/517 (35%), Positives = 273/517 (52%), Gaps = 33/517 (6%)

Query: 24  DHVNLQAVKKKFKEFMR-QFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAE 82
           D V L+  ++ + +F+  +   G +  K R+ +  N    QY + +N+ DL   ++  A 
Sbjct: 8   DDVELREAQRDYLDFLDDEEDQGIYQSKVRELISDN----QYRLIVNVNDLRRKNEKRAN 63

Query: 83  KLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNL--RELKSET 140
           +L     E L                   +   + E+  V L     S ++  R L S  
Sbjct: 64  RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120

Query: 141 VSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYV-MPRKCNTEQSG 199
           +S +V + GIV   S ++ K  +    C + +  I        L   V  P         
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERR--YSDLTTLVAFPSSSVYPTKD 178

Query: 200 RPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARV 259
               PL+  + +       D+Q + +QE PE  P G++PR + V  D  L ++   G RV
Sbjct: 179 EENNPLETEYGLS---VYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKANAGDRV 235

Query: 260 TVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAE-EGVTSGLRP-FTAEEEEQFR 317
            V+G Y        G++G      G  S   R V +    + ++   +P F+AE+  + +
Sbjct: 236 QVVGTYRCLP----GKKG------GYTSGTFRTVLIACNVKQMSKDAQPSFSAEDIAKIK 285

Query: 318 RLAA--SPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLG 375
           + +   S DI++++ KS+APS+ G   +KKAI CLL GG  + L +G   RGDINILL+G
Sbjct: 286 KFSKTRSKDIFDQLAKSLAPSIHGHDYVKKAILCLLLGGVERDLENGSHIRGDINILLIG 345

Query: 376 DPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGV 435
           DP  AKSQLL++V   AP  + T+G+GSS  GLTA+V  D  +    +E GAMVLAD GV
Sbjct: 346 DPSVAKSQLLRYVLCTAPRAIPTTGRGSSGVGLTAAVTTDQETGERRLEAGAMVLADRGV 405

Query: 436 VCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKAD 495
           VCIDEFDKM + DR AIHE MEQ  ++IAKAGI   LN+RCSVLAAAN V+GR+D  K  
Sbjct: 406 VCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCSVLAAANPVYGRYDQYKTP 465

Query: 496 -DNIDFMPTILSRFDMIFIVKDEHD--QNRDIARYVL 529
            +NI    ++LSRFD++FI+ D+ D  Q+R+I+ +VL
Sbjct: 466 MENIGLQDSLLSRFDLLFIMLDQMDPEQDREISDHVL 502


>X67334-1|CAA47749.1|  892|Homo sapiens polypeptide BM28 protein.
          Length = 892

 Score =  261 bits (639), Expect = 7e-69
 Identities = 167/503 (33%), Positives = 266/503 (52%), Gaps = 21/503 (4%)

Query: 31  VKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSSFDDVLAEKLYKKPTE 90
           +  +FK F+R     + +  +++ +      N+  + +N EDL++ + VLA  L + P E
Sbjct: 184 IHHRFKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAE 243

Query: 91  HLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRELKSETVSRLVKIPGI 150
            L I                P+ +     I V +S       LR L+   +++L++  G+
Sbjct: 244 LLQIFDEAALEVVLAMY---PKYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGV 300

Query: 151 VISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNTEQSGRPKCPLDPYFI 210
           V S +G+  + + +   C  C  V+   P        V P  C   QS        P+ +
Sbjct: 301 VTSCTGVLPQLSMVKYNCNKCNFVLG--PFCQSQNQEVKPGSCPECQSA------GPFEV 352

Query: 211 IPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKI 270
             ++    +YQ +++QE+P  +    +PR         L +    G  + + GIY     
Sbjct: 353 NMEETIYQNYQRIRIQESPGKVAARRLPRSKDAILLADLVDSCNAGDEIELTGIYHNNYD 412

Query: 271 AKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTAEEEEQFRRLAASPDIYERIG 330
             +           V ++ + A  +  ++   + +   T E+ +    L+    I E+I 
Sbjct: 413 GSLNTAN----GFPVFATVILANHVAKKDNKVA-VGELTDEDVKMITSLSKDQQIGEKIF 467

Query: 331 KSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTR-RGDINILLLGDPGTAKSQLLKFVE 389
            SIAPS++G  D+K+  A  LFGG  K  P G  + RGDIN+LL GDPGTAKSQ LK++E
Sbjct: 468 ASIAPSIYGHEDIKRGPALALFGGEPKN-PGGKHKVRGDINVLLCGDPGTAKSQFLKYIE 526

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
           KV+   ++T+G+G+SA  +TA V R P SR + +E GA+VLAD GV  IDEFDKM + DR
Sbjct: 527 KVSSRAIFTTGQGASAVAVTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDR 586

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRF 508
            +IHEAMEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRF
Sbjct: 587 TSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRF 646

Query: 509 DMIFIVKDEHD--QNRDIARYVL 529
           D++ +V+D  D  Q+  +AR+V+
Sbjct: 647 DILCVVRDTVDPVQDEMLARFVV 669


>D84557-1|BAA12699.1|  821|Homo sapiens HsMcm6 protein.
          Length = 821

 Score =  227 bits (555), Expect = 1e-58
 Identities = 114/229 (49%), Positives = 156/229 (68%), Gaps = 1/229 (0%)

Query: 298 EEGVTSGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRK 357
           E+   S     T +E E+   ++   ++Y  +  S+ P++ G  ++K+ +  +LFGG  K
Sbjct: 319 EQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPK 378

Query: 358 RLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
              +G + RGDIN+ ++GDP TAKSQ LK VE+ +P  VYTSGK SSAAGLTA+V+RD  
Sbjct: 379 TTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEE 438

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S  FV+E GA++LAD GV CIDEFDKM   D+VAIHEAMEQQTISI KAG+  TLN+R S
Sbjct: 439 SHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTS 498

Query: 478 VLAAANSVFGRWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIA 525
           +LAAAN + G +D +K+   NI+    I+SRFD+ FI+ DE ++  D A
Sbjct: 499 ILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYA 547



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 53/264 (20%), Positives = 102/264 (38%), Gaps = 16/264 (6%)

Query: 16  GVEENESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSS 75
           G +  E +D V  +  +K F +F+ +F + +   KY    +      +  + ++  DL  
Sbjct: 12  GSQHLEVRDEV-AEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQ 70

Query: 76  FDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRE 135
           F+  L+  + ++     P                R E     +D  V          +RE
Sbjct: 71  FNQQLSTTIQEEFYRVYPYLCRALKTFVKD----RKE-IPLAKDFYVAFQDLPTRHKIRE 125

Query: 136 LKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNT 195
           L S  +  L +I G V+    +  +    +  C  C+ VI ++  +     Y  P  C  
Sbjct: 126 LTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQ---FKYTQPNICRN 182

Query: 196 EQSGRPKCPLDPYFIIP-DKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVA 254
                P C     F++  +K + +D+Q +++QE    +P+G +PR L V       E   
Sbjct: 183 -----PVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQ 237

Query: 255 PGARVTVLG-IYSIKKIAKVGREG 277
            G +    G +  +  ++K+   G
Sbjct: 238 AGDKCDFTGTLIVVPDVSKLSTPG 261



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 4/59 (6%)

Query: 536 QHERQAD----KRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +H RQ D     + S  ITVRQLE+++R+SE++A+M         HV EA RL   S +
Sbjct: 599 KHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 657


>BC032374-1|AAH32374.1|  821|Homo sapiens minichromosome maintenance
           complex component 6 protein.
          Length = 821

 Score =  227 bits (555), Expect = 1e-58
 Identities = 114/229 (49%), Positives = 156/229 (68%), Gaps = 1/229 (0%)

Query: 298 EEGVTSGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRK 357
           E+   S     T +E E+   ++   ++Y  +  S+ P++ G  ++K+ +  +LFGG  K
Sbjct: 319 EQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPK 378

Query: 358 RLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
              +G + RGDIN+ ++GDP TAKSQ LK VE+ +P  VYTSGK SSAAGLTA+V+RD  
Sbjct: 379 TTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEE 438

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S  FV+E GA++LAD GV CIDEFDKM   D+VAIHEAMEQQTISI KAG+  TLN+R S
Sbjct: 439 SHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTS 498

Query: 478 VLAAANSVFGRWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIA 525
           +LAAAN + G +D +K+   NI+    I+SRFD+ FI+ DE ++  D A
Sbjct: 499 ILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYA 547



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 53/264 (20%), Positives = 102/264 (38%), Gaps = 16/264 (6%)

Query: 16  GVEENESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSS 75
           G +  E +D V  +  +K F +F+ +F + +   KY    +      +  + ++  DL  
Sbjct: 12  GSQHLEVRDEV-AEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQ 70

Query: 76  FDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRE 135
           F+  L+  + ++     P                R E     +D  V          +RE
Sbjct: 71  FNQQLSTTIQEEFYRVYPYLCRALKTFVKD----RKE-IPLAKDFYVAFQDLPTRHKIRE 125

Query: 136 LKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNT 195
           L S  +  L +I G V+    +  +    +  C  C+ VI ++  +     Y  P  C  
Sbjct: 126 LTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQ---FKYTQPNICRN 182

Query: 196 EQSGRPKCPLDPYFIIP-DKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVA 254
                P C     F++  +K + +D+Q +++QE    +P+G +PR L V       E   
Sbjct: 183 -----PVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQ 237

Query: 255 PGARVTVLG-IYSIKKIAKVGREG 277
            G +    G +  +  ++K+   G
Sbjct: 238 AGDKCDFTGTLIVVPDVSKLSTPG 261



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 4/59 (6%)

Query: 536 QHERQAD----KRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +H RQ D     + S  ITVRQLE+++R+SE++A+M         HV EA RL   S +
Sbjct: 599 KHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 657


>AY220757-1|AAO26043.1|  821|Homo sapiens MCM6 minichromosome
           maintenance deficient 6 (MIS5 homolog, S. pombe) (S.
           cerevi protein.
          Length = 821

 Score =  227 bits (555), Expect = 1e-58
 Identities = 114/229 (49%), Positives = 156/229 (68%), Gaps = 1/229 (0%)

Query: 298 EEGVTSGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRK 357
           E+   S     T +E E+   ++   ++Y  +  S+ P++ G  ++K+ +  +LFGG  K
Sbjct: 319 EQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPK 378

Query: 358 RLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
              +G + RGDIN+ ++GDP TAKSQ LK VE+ +P  VYTSGK SSAAGLTA+V+RD  
Sbjct: 379 TTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEE 438

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S  FV+E GA++LAD GV CIDEFDKM   D+VAIHEAMEQQTISI KAG+  TLN+R S
Sbjct: 439 SHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTS 498

Query: 478 VLAAANSVFGRWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIA 525
           +LAAAN + G +D +K+   NI+    I+SRFD+ FI+ DE ++  D A
Sbjct: 499 ILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYA 547



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 53/264 (20%), Positives = 102/264 (38%), Gaps = 16/264 (6%)

Query: 16  GVEENESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSS 75
           G +  E +D V  +  +K F +F+ +F + +   KY    +      +  + ++  DL  
Sbjct: 12  GSQHLEVRDEV-AEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQ 70

Query: 76  FDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRE 135
           F+  L+  + ++     P                R E     +D  V          +RE
Sbjct: 71  FNQQLSTTIQEEFYRVYPYLCRALKTFVKD----RKE-IPLAKDFYVAFQDLPTRHKIRE 125

Query: 136 LKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNT 195
           L S  +  L +I G V+    +  +    +  C  C+ VI ++  +     Y  P  C  
Sbjct: 126 LTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQ---FKYTQPNICRN 182

Query: 196 EQSGRPKCPLDPYFIIP-DKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVA 254
                P C     F++  +K + +D+Q +++QE    +P+G +PR L V       E   
Sbjct: 183 -----PVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQ 237

Query: 255 PGARVTVLG-IYSIKKIAKVGREG 277
            G +    G +  +  ++K+   G
Sbjct: 238 AGDKCDFTGTLIVVPDVSKLSTPG 261



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 4/59 (6%)

Query: 536 QHERQAD----KRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +H RQ D     + S  ITVRQLE+++R+SE++A+M         HV EA RL   S +
Sbjct: 599 KHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 657


>AC011893-4|AAX88925.1|  785|Homo sapiens unknown protein.
          Length = 785

 Score =  227 bits (555), Expect = 1e-58
 Identities = 114/229 (49%), Positives = 156/229 (68%), Gaps = 1/229 (0%)

Query: 298 EEGVTSGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRK 357
           E+   S     T +E E+   ++   ++Y  +  S+ P++ G  ++K+ +  +LFGG  K
Sbjct: 283 EQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPK 342

Query: 358 RLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
              +G + RGDIN+ ++GDP TAKSQ LK VE+ +P  VYTSGK SSAAGLTA+V+RD  
Sbjct: 343 TTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEE 402

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S  FV+E GA++LAD GV CIDEFDKM   D+VAIHEAMEQQTISI KAG+  TLN+R S
Sbjct: 403 SHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTS 462

Query: 478 VLAAANSVFGRWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIA 525
           +LAAAN + G +D +K+   NI+    I+SRFD+ FI+ DE ++  D A
Sbjct: 463 ILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYA 511



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 34/147 (23%), Positives = 63/147 (42%), Gaps = 10/147 (6%)

Query: 133 LRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRK 192
           +REL S  +  L +I G V+    +  +    +  C  C+ VI ++  +     Y  P  
Sbjct: 87  IRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQ---FKYTQPNI 143

Query: 193 CNTEQSGRPKCPLDPYFIIP-DKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCE 251
           C       P C     F++  +K + +D+Q +++QE    +P+G +PR L V       E
Sbjct: 144 CRN-----PVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVE 198

Query: 252 RVAPGARVTVLG-IYSIKKIAKVGREG 277
               G +    G +  +  ++K+   G
Sbjct: 199 SAQAGDKCDFTGTLIVVPDVSKLSTPG 225



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 4/59 (6%)

Query: 536 QHERQAD----KRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +H RQ D     + S  ITVRQLE+++R+SE++A+M         HV EA RL   S +
Sbjct: 563 KHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 621


>U46838-1|AAC50766.1|  821|Homo sapiens p105MCM protein.
          Length = 821

 Score =  217 bits (531), Expect = 8e-56
 Identities = 112/229 (48%), Positives = 152/229 (66%), Gaps = 1/229 (0%)

Query: 298 EEGVTSGLRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRK 357
           E+   S     T +E E+   ++   ++Y  +  S+ P++ G  ++K+ +  +LFGG  K
Sbjct: 319 EQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVSK 378

Query: 358 RLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
                    GDIN+ ++GDP TAKSQ LK VE+ +P  VYTSGK SSAAGLTA+V+RD  
Sbjct: 379 DNRRRDLSSGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEE 438

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S  FV+E GA++LAD GV CIDEFDKM   D+VAIHEAMEQQTISI KAG+  TLN+R S
Sbjct: 439 SHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNTRTS 498

Query: 478 VLAAANSVFGRWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIA 525
           +LAAAN + G +D +K+   NI+    I+SRFD+ FI+ DE ++  D A
Sbjct: 499 ILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYA 547



 Score = 52.4 bits (120), Expect = 5e-06
 Identities = 53/264 (20%), Positives = 102/264 (38%), Gaps = 16/264 (6%)

Query: 16  GVEENESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYRDALKRNYNLNQYWVEINIEDLSS 75
           G +  E +D V  +  +K F +F+ +F + +   KY    +      +  + ++  DL  
Sbjct: 12  GSQHLEVRDEV-AEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQ 70

Query: 76  FDDVLAEKLYKKPTEHLPIXXXXXXXXXXXXXXPRPEGEEKVEDIQVLLSSDAHSSNLRE 135
           F+  L+  + ++     P                R E     +D  V          +RE
Sbjct: 71  FNQQLSTTIQEEFYRVYPYLCRALKTFVKD----RKE-IPLAKDFYVAFQDLPTRHKIRE 125

Query: 136 LKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMPRKCNT 195
           L S  +  L +I G V+    +  +    +  C  C+ VI ++  +     Y  P  C  
Sbjct: 126 LTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQ---FKYTQPNICRN 182

Query: 196 EQSGRPKCPLDPYFIIP-DKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLCERVA 254
                P C     F++  +K + +D+Q +++QE    +P+G +PR L V       E   
Sbjct: 183 -----PVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQ 237

Query: 255 PGARVTVLG-IYSIKKIAKVGREG 277
            G +    G +  +  ++K+   G
Sbjct: 238 AGDKCDFTGTLIVVPDVSKLSTPG 261



 Score = 40.7 bits (91), Expect = 0.016
 Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 4/59 (6%)

Query: 536 QHERQAD----KRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +H RQ D     + S  ITVRQLE+++R+SE++A+M         HV EA RL   S +
Sbjct: 599 KHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSII 657


>AY007130-1|AAG01994.1|  351|Homo sapiens protein ( Homo sapiens
           clone CDABP0042 mRNA sequence. ).
          Length = 351

 Score =  209 bits (511), Expect = 2e-53
 Identities = 108/217 (49%), Positives = 148/217 (68%), Gaps = 6/217 (2%)

Query: 366 RGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEG 425
           RG+INI L+GDPG AKSQLL +++++AP   YT+G+GSS  GLTA+V+RD  S    +EG
Sbjct: 4   RGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEG 63

Query: 426 GAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSV 485
           GA+VLAD GV CIDEFDKM E DR AIHE MEQQTISIAKAGI TTLN+RCS+LAAAN  
Sbjct: 64  GALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPA 123

Query: 486 FGRWDDTKA-DDNIDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKR 544
           +GR++  ++ + NI     +LSRFD++++++D  D++ D+ R     T   QH RQ   +
Sbjct: 124 YGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDL-RLAQHITYVHQHSRQPPSQ 182

Query: 545 LSIPI---TVRQLEAIVRISESLAKMQLQPFATEAHV 578
              P+    +R+  A+ R  + +    L  + T A+V
Sbjct: 183 FE-PLDMKLMRRYIAMCREKQPMVPESLADYITAAYV 218



 Score = 34.7 bits (76), Expect = 1.1
 Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 1/65 (1%)

Query: 524 IARYVLMRTGALQHERQADKRLSIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALR 583
           +A Y+      ++ E  A K  +   + R L AI+R+S +LA++++     +  VNEA+R
Sbjct: 209 LADYITAAYVEMRREAWASKDATYT-SARTLLAILRLSTALARLRMVDVVEKEDVNEAIR 267

Query: 584 LFQVS 588
           L ++S
Sbjct: 268 LMEMS 272


>BC101057-1|AAI01058.1|  840|Homo sapiens MCM8 protein protein.
          Length = 840

 Score =  203 bits (496), Expect = 1e-51
 Identities = 132/407 (32%), Positives = 217/407 (53%), Gaps = 23/407 (5%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGV---RSSYLRAVGL---TAEEG 300
             L +   PG  VT+ GI  +    +  R   DK    +    +S   + G    ++E+G
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDG 376

Query: 301 VTSG-LRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRL 359
              G L  F+ ++    + + A  ++++ I  S+ P +FG   +K  +A  LFGGS+K  
Sbjct: 377 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 436

Query: 360 PDG--LTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
            D   +  RGD +IL++GDPG  KSQ+L+    VAP GVY  G  ++ +GLT ++ +D  
Sbjct: 437 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 496

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S +F +E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+IS+AKAG+  +L +R S
Sbjct: 497 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTS 555

Query: 478 VLAAANSVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHDQNRD 523
           ++AAAN V G ++  K   +N+     +LSRFD++FI+ D  +++ D
Sbjct: 556 IIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHD 602



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 599 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 657

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 658 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 716

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 717 IRLTEARARLELREEATKEDAEDIVEIMKYSML 749


>BC101056-1|AAI01057.1|  840|Homo sapiens minichromosome maintenance
           complex component 8 protein.
          Length = 840

 Score =  203 bits (496), Expect = 1e-51
 Identities = 132/407 (32%), Positives = 217/407 (53%), Gaps = 23/407 (5%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGV---RSSYLRAVGL---TAEEG 300
             L +   PG  VT+ GI  +    +  R   DK    +    +S   + G    ++E+G
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDG 376

Query: 301 VTSG-LRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRL 359
              G L  F+ ++    + + A  ++++ I  S+ P +FG   +K  +A  LFGGS+K  
Sbjct: 377 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 436

Query: 360 PDG--LTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
            D   +  RGD +IL++GDPG  KSQ+L+    VAP GVY  G  ++ +GLT ++ +D  
Sbjct: 437 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 496

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S +F +E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+IS+AKAG+  +L +R S
Sbjct: 497 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTS 555

Query: 478 VLAAANSVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHDQNRD 523
           ++AAAN V G ++  K   +N+     +LSRFD++FI+ D  +++ D
Sbjct: 556 IIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHD 602



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 599 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 657

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 658 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 716

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 717 IRLTEARARLELREEATKEDAEDIVEIMKYSML 749


>BC080656-1|AAH80656.1|  840|Homo sapiens minichromosome maintenance
           complex component 8 protein.
          Length = 840

 Score =  203 bits (496), Expect = 1e-51
 Identities = 132/407 (32%), Positives = 217/407 (53%), Gaps = 23/407 (5%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGV---RSSYLRAVGL---TAEEG 300
             L +   PG  VT+ GI  +    +  R   DK    +    +S   + G    ++E+G
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDG 376

Query: 301 VTSG-LRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRL 359
              G L  F+ ++    + + A  ++++ I  S+ P +FG   +K  +A  LFGGS+K  
Sbjct: 377 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 436

Query: 360 PDG--LTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
            D   +  RGD +IL++GDPG  KSQ+L+    VAP GVY  G  ++ +GLT ++ +D  
Sbjct: 437 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 496

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S +F +E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+IS+AKAG+  +L +R S
Sbjct: 497 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTS 555

Query: 478 VLAAANSVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHDQNRD 523
           ++AAAN V G ++  K   +N+     +LSRFD++FI+ D  +++ D
Sbjct: 556 IIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHD 602



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 599 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 657

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 658 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 716

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 717 IRLTEARARLELREEATKEDAEDIVEIMKYSML 749


>BC008830-1|AAH08830.2|  735|Homo sapiens MCM8 protein protein.
          Length = 735

 Score =  203 bits (496), Expect = 1e-51
 Identities = 132/407 (32%), Positives = 217/407 (53%), Gaps = 23/407 (5%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 100 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 156

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 157 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 211

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGV---RSSYLRAVGL---TAEEG 300
             L +   PG  VT+ GI  +    +  R   DK    +    +S   + G    ++E+G
Sbjct: 212 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDG 271

Query: 301 VTSG-LRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRL 359
              G L  F+ ++    + + A  ++++ I  S+ P +FG   +K  +A  LFGGS+K  
Sbjct: 272 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 331

Query: 360 PDG--LTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
            D   +  RGD +IL++GDPG  KSQ+L+    VAP GVY  G  ++ +GLT ++ +D  
Sbjct: 332 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 391

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S +F +E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+IS+AKAG+  +L +R S
Sbjct: 392 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTS 450

Query: 478 VLAAANSVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHDQNRD 523
           ++AAAN V G ++  K   +N+     +LSRFD++FI+ D  +++ D
Sbjct: 451 IIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHD 497



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 494 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 552

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 553 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 611

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 612 IRLTEARARLELREEATKEDAEDIVEIMKYSML 644


>AL035461-6|CAB55276.2|  840|Homo sapiens MCM8 minichromosome
           maintenance deficient 8 (S. cerevisiae) protein.
          Length = 840

 Score =  203 bits (496), Expect = 1e-51
 Identities = 132/407 (32%), Positives = 217/407 (53%), Gaps = 23/407 (5%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGV---RSSYLRAVGL---TAEEG 300
             L +   PG  VT+ GI  +    +  R   DK    +    +S   + G    ++E+G
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDG 376

Query: 301 VTSG-LRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRL 359
              G L  F+ ++    + + A  ++++ I  S+ P +FG   +K  +A  LFGGS+K  
Sbjct: 377 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 436

Query: 360 PDG--LTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
            D   +  RGD +IL++GDPG  KSQ+L+    VAP GVY  G  ++ +GLT ++ +D  
Sbjct: 437 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 496

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S +F +E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+IS+AKAG+  +L +R S
Sbjct: 497 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTS 555

Query: 478 VLAAANSVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHDQNRD 523
           ++AAAN V G ++  K   +N+     +LSRFD++FI+ D  +++ D
Sbjct: 556 IIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHD 602



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 599 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 657

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 658 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 716

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 717 IRLTEARARLELREEATKEDAEDIVEIMKYSML 749


>AJ439063-1|CAD27750.1|  840|Homo sapiens minichromosome maintenance
           8 protein.
          Length = 840

 Score =  203 bits (496), Expect = 1e-51
 Identities = 132/407 (32%), Positives = 217/407 (53%), Gaps = 23/407 (5%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGV---RSSYLRAVGL---TAEEG 300
             L +   PG  VT+ GI  +    +  R   DK    +    +S   + G    ++E+G
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDG 376

Query: 301 VTSG-LRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRL 359
              G L  F+ ++    + + A  ++++ I  S+ P +FG   +K  +A  LFGGS+K  
Sbjct: 377 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYA 436

Query: 360 PDG--LTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPG 417
            D   +  RGD +IL++GDPG  KSQ+L+    VAP GVY  G  ++ +GLT ++ +D  
Sbjct: 437 DDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSS 496

Query: 418 SRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCS 477
           S +F +E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+IS+AKAG+  +L +R S
Sbjct: 497 SGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTS 555

Query: 478 VLAAANSVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHDQNRD 523
           ++AAAN V G ++  K   +N+     +LSRFD++FI+ D  +++ D
Sbjct: 556 IIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHD 602



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 599 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 657

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 658 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 716

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 717 IRLTEARARLELREEATKEDAEDIVEIMKYSML 749


>AY158211-1|AAO21222.1|  824|Homo sapiens MCM8 isoform protein.
          Length = 824

 Score =  202 bits (494), Expect = 2e-51
 Identities = 131/401 (32%), Positives = 212/401 (52%), Gaps = 27/401 (6%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSG-L 305
             L +   PG  VT+ GI  +    +       KG    +SS         E+G   G L
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEANSISNSKGQK-TKSS---------EDGCKHGML 366

Query: 306 RPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDG--L 363
             F+ ++    + + A  ++++ I  S+ P +FG   +K  +A  LFGGS+K   D   +
Sbjct: 367 MEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRI 426

Query: 364 TRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVM 423
             RGD +IL++GDPG  KSQ+L+    VAP GVY  G  ++ +GLT ++ +D  S +F +
Sbjct: 427 PIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFAL 486

Query: 424 EGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAAN 483
           E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+IS+AKAG+  +L +R S++AAAN
Sbjct: 487 EAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAAN 545

Query: 484 SVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHDQNRD 523
            V G ++  K   +N+     +LSRFD++FI+ D  +++ D
Sbjct: 546 PVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHD 586



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 583 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 641

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 642 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 700

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 701 IRLTEARARLELREEATKEDAEDIVEIMKYSML 733


>AL035461-7|CAI23480.1|  824|Homo sapiens MCM8 minichromosome
           maintenance deficient 8 (S. cerevisiae) protein.
          Length = 824

 Score =  202 bits (494), Expect = 2e-51
 Identities = 131/401 (32%), Positives = 212/401 (52%), Gaps = 27/401 (6%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSG-L 305
             L +   PG  VT+ GI  +    +       KG    +SS         E+G   G L
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEANSISNSKGQK-TKSS---------EDGCKHGML 366

Query: 306 RPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDG--L 363
             F+ ++    + + A  ++++ I  S+ P +FG   +K  +A  LFGGS+K   D   +
Sbjct: 367 MEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRI 426

Query: 364 TRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVM 423
             RGD +IL++GDPG  KSQ+L+    VAP GVY  G  ++ +GLT ++ +D  S +F +
Sbjct: 427 PIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFAL 486

Query: 424 EGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAAN 483
           E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+IS+AKAG+  +L +R S++AAAN
Sbjct: 487 EAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAAN 545

Query: 484 SVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHDQNRD 523
            V G ++  K   +N+     +LSRFD++FI+ D  +++ D
Sbjct: 546 PVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHD 586



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 583 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 641

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 642 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 700

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 701 IRLTEARARLELREEATKEDAEDIVEIMKYSML 733


>AK027644-1|BAB55260.1|  603|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14738 fis, clone NT2RP3002399, weakly similar to
           DNA REPLICATION LICENSING FACTOR MCM4. ).
          Length = 603

 Score =  186 bits (454), Expect = 2e-46
 Identities = 113/318 (35%), Positives = 181/318 (56%), Gaps = 13/318 (4%)

Query: 218 IDYQVLKLQE--APESIPQGEMPRHLTVYCDRTLCERVAPGARVTVLGIYSIKKIAKVGR 275
           +D+Q +K+QE  + +    G +PR +       L +   PG  VT+ GI  +    +  R
Sbjct: 49  MDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSR 108

Query: 276 EGRDKGSVGV---RSSYLRAVGL---TAEEGVTSG-LRPFTAEEEEQFRRLAASPDIYER 328
              DK    +    +S   + G    ++E+G   G L  F+ ++    + + A  ++++ 
Sbjct: 109 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 168

Query: 329 IGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDG--LTRRGDINILLLGDPGTAKSQLLK 386
           I  S+ P +FG   +K  +A  LFGGS+K   D   +  RGD +IL++GDPG  KSQ+L+
Sbjct: 169 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 228

Query: 387 FVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMRE 446
               VAP GVY  G  ++ +GLT ++ +D  S +F +E GA+VL D G+  IDEFDKM  
Sbjct: 229 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 288

Query: 447 DDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTK-ADDNIDFMPTIL 505
             + A+ EAMEQQ+IS+AKAG+  +L +R S++AAAN V G ++  K   +N+     +L
Sbjct: 289 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 347

Query: 506 SRFDMIFIVKDEHDQNRD 523
           SRFD++FI+ D  +++ D
Sbjct: 348 SRFDLVFILLDTPNEHHD 365



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 362 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 420

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 421 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 479

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 480 IRLTEARARLELREEATKEDAEDIVEIMKYSML 512


>AK160378-1|BAD18721.1|  450|Homo sapiens FLJ00323 protein protein.
          Length = 450

 Score =  157 bits (380), Expect = 2e-37
 Identities = 85/195 (43%), Positives = 125/195 (64%), Gaps = 4/195 (2%)

Query: 332 SIAPSVFGAVDMKKAIACLLFGGSRKRLPDG--LTRRGDINILLLGDPGTAKSQLLKFVE 389
           S+  S F    +K  +A  LFGGS+K   D   +  RGD +IL++GDPG  KSQ+L+   
Sbjct: 19  SVFCSFFALELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAAC 78

Query: 390 KVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDR 449
            VAP GVY  G  ++ +GLT ++ +D  S +F +E GA+VL D G+  IDEFDKM    +
Sbjct: 79  NVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ 138

Query: 450 VAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTK-ADDNIDFMPTILSRF 508
            A+ EAMEQQ+IS+AKAG+  +L +R S++AAAN V G ++  K   +N+     +LSRF
Sbjct: 139 -ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRF 197

Query: 509 DMIFIVKDEHDQNRD 523
           D++FI+ D  +++ D
Sbjct: 198 DLVFILLDTPNEHHD 212



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 209 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 267

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 268 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 326

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 327 IRLTEARARLELREEATKEDAEDIVEIMKYSML 359


>BC101055-1|AAI01056.1|  880|Homo sapiens MCM8 protein protein.
          Length = 880

 Score =  153 bits (372), Expect = 1e-36
 Identities = 82/184 (44%), Positives = 120/184 (65%), Gaps = 4/184 (2%)

Query: 343 MKKAIACLLFGGSRKRLPDG--LTRRGDINILLLGDPGTAKSQLLKFVEKVAPIGVYTSG 400
           +K  +A  LFGGS+K   D   +  RGD +IL++GDPG  KSQ+L+    VAP GVY  G
Sbjct: 460 VKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCG 519

Query: 401 KGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQT 460
             ++ +GLT ++ +D  S +F +E GA+VL D G+  IDEFDKM    + A+ EAMEQQ+
Sbjct: 520 NTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQS 578

Query: 461 ISIAKAGITTTLNSRCSVLAAANSVFGRWDDTK-ADDNIDFMPTILSRFDMIFIVKDEHD 519
           IS+AKAG+  +L +R S++AAAN V G ++  K   +N+     +LSRFD+ FI+ D  +
Sbjct: 579 ISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLAFILLDTPN 638

Query: 520 QNRD 523
           ++ D
Sbjct: 639 EHHD 642



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 37/154 (24%), Positives = 66/154 (42%), Gaps = 12/154 (7%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDK 280
             L +   PG  VT+ GI  +    +  R   DK
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDK 350



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 639 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 697

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 698 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 756

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 757 IRLTEARARLELREEATKEDAEDIVEIMKYSML 789


>BC000300-1|AAH00300.2|  362|Homo sapiens MCM2 protein protein.
          Length = 362

 Score =  149 bits (361), Expect = 3e-35
 Identities = 73/137 (53%), Positives = 103/137 (75%), Gaps = 3/137 (2%)

Query: 396 VYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEA 455
           ++T+G+G+SA GLTA V R P SR + +E GA+VLAD GV  IDEFDKM + DR +IHEA
Sbjct: 2   IFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEA 61

Query: 456 MEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTKA-DDNIDFMPTILSRFDMIFIV 514
           MEQQ+ISI+KAGI T+L +RC+V+AAAN + GR+D +    +N+D    I+SRFD++ +V
Sbjct: 62  MEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCVV 121

Query: 515 KDEHD--QNRDIARYVL 529
           +D  D  Q+  +AR+V+
Sbjct: 122 RDTVDPVQDEMLARFVV 138



 Score = 42.7 bits (96), Expect = 0.004
 Identities = 19/46 (41%), Positives = 33/46 (71%)

Query: 546 SIPITVRQLEAIVRISESLAKMQLQPFATEAHVNEALRLFQVSTLD 591
           SIPITVR +E+++R++E+ A++ L+ +  E  VN A+R+   S +D
Sbjct: 217 SIPITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFID 262


>BC101054-1|AAI01055.1|  793|Homo sapiens MCM8 protein protein.
          Length = 793

 Score =  119 bits (286), Expect = 4e-26
 Identities = 60/134 (44%), Positives = 90/134 (67%), Gaps = 2/134 (1%)

Query: 391 VAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRV 450
           VAP GVY  G  ++ +GLT ++ +D  S +F +E GA+VL D G+  IDEFDKM    + 
Sbjct: 423 VAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ- 481

Query: 451 AIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDDTK-ADDNIDFMPTILSRFD 509
           A+ EAMEQQ+IS+AKAG+  +L +R S++AAAN V G ++  K   +N+     +LSRFD
Sbjct: 482 ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFD 541

Query: 510 MIFIVKDEHDQNRD 523
           ++FI+ D  +++ D
Sbjct: 542 LVFILLDTPNEHHD 555



 Score = 55.6 bits (128), Expect = 5e-07
 Identities = 50/220 (22%), Positives = 96/220 (43%), Gaps = 19/220 (8%)

Query: 131 SNLRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVMP 190
           + L+ +++    + + + G V+  S IK   TK++  C +C   I + P+  G   Y +P
Sbjct: 205 TQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGE-IQSFPLPDGK--YSLP 261

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCI--DYQVLKLQE--APESIPQGEMPRHLTVYCD 246
            KC       P C    +  +      +  D+Q +K+QE  + +    G +PR +     
Sbjct: 262 TKCPV-----PVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELV 316

Query: 247 RTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGV---RSSYLRAVG---LTAEEG 300
             L +   PG  VT+ GI  +    +  R   DK    +    +S   + G    ++E+G
Sbjct: 317 HDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDG 376

Query: 301 VTSG-LRPFTAEEEEQFRRLAASPDIYERIGKSIAPSVFG 339
              G L  F+ ++    + + A  ++++ I  S+ P +FG
Sbjct: 377 CKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFG 416



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 39/153 (25%), Positives = 75/153 (49%), Gaps = 3/153 (1%)

Query: 439 DEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVL-AAANSVFGRWDDTKADDN 497
           +  D +  +  +AI  A +Q+TIS A      + +S  SVL   +             + 
Sbjct: 552 EHHDHLLSEHVIAIR-AGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGET 610

Query: 498 IDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLSIPITVRQLEAI 557
           ID +P  L R  + +  +  + +    A  VL +   L+  +Q+ +  S PIT RQLE++
Sbjct: 611 IDPIPHQLLRKYIGYARQYVYPRLSTEAARVL-QDFYLELRKQSQRLNSSPITTRQLESL 669

Query: 558 VRISESLAKMQLQPFATEAHVNEALRLFQVSTL 590
           +R++E+ A+++L+  AT+    + + + + S L
Sbjct: 670 IRLTEARARLELREEATKEDAEDIVEIMKYSML 702


>AL132874-5|CAI42607.1|  451|Homo sapiens protein ( an).  ).).
          Length = 451

 Score =  114 bits (275), Expect = 8e-25
 Identities = 110/448 (24%), Positives = 208/448 (46%), Gaps = 31/448 (6%)

Query: 137 KSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVM---PRKC 193
           K++ V   + + G VI  S +K    +    C  C++V     +K   E Y     P  C
Sbjct: 6   KTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFV---IKADFEQYYTFCRPSSC 62

Query: 194 NTEQS---GRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLC 250
            + +S    +  C L      P +C+  DYQ +K+QE  + +  G +PR + V  +  L 
Sbjct: 63  PSLESCDSSKFTC-LSGLSSSPTRCR--DYQEIKIQEQVQRLSVGSIPRSMKVILEDDLV 119

Query: 251 ERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTA 310
           +    G  +T+ GI  +++     ++ R +  + ++++Y++ V      G+   +     
Sbjct: 120 DSCKSGDDLTIYGIV-MQRWKPFQQDVRCEVEIVLKANYIQ-VNNEQSSGII--MDEEVQ 175

Query: 311 EEEEQFRRLAASPDIYER--IGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGD 368
           +E E F     S     R  I  S+ P VFG   +K A+A +L GG ++    G   RG+
Sbjct: 176 KEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGE 235

Query: 369 INILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGLTASVIRDPGSRNFVMEGGAM 428
            ++LL+GDPGT KSQ LK+  K+ P  V T+G GS++AG+  +    PGS    +     
Sbjct: 236 SHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGIVLNCTVSPGSLVCKLNTRTT 295

Query: 429 VLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAK--AGITTTLNSRCSVLAAANSVF 486
           +LA       +   +    + V+++ A+    +S       +  T N     + ++  + 
Sbjct: 296 ILA-----ATNPKGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILE 350

Query: 487 GRWDDTKADDNIDFMPTILSRFDMIFIVKDEHDQNRDIARYVLMRTGALQHERQADKRLS 546
            +   +K+ + +  M  + + F    ++++      D+   VL+R    Q +RQ+D R +
Sbjct: 351 NKGYPSKS-EKLWSMEKMKTYF---CLIRNLQPTLSDVGNQVLLR--YYQMQRQSDCRNA 404

Query: 547 IPITVRQLEAIVRISESLAKMQLQPFAT 574
              T+R LE+++R++E+ A++  +   T
Sbjct: 405 ARTTIRLLESLIRLAEAHARLMFRDTVT 432


>BC031658-1|AAH31658.1|  391|Homo sapiens minichromosome maintenance
           complex component 9 protein.
          Length = 391

 Score =  104 bits (249), Expect = 1e-21
 Identities = 80/280 (28%), Positives = 136/280 (48%), Gaps = 18/280 (6%)

Query: 137 KSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVM---PRKC 193
           K++ V   + + G VI  S +K    +    C  C++V     +K   E Y     P  C
Sbjct: 116 KTKDVGHFLSVTGTVIRTSLVKVLEFERDYMCNKCKHVFV---IKADFEQYYTFCRPSSC 172

Query: 194 NTEQS---GRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLC 250
            + +S    +  C L      P +C+  DYQ +K+QE  + +  G +PR + V  +  L 
Sbjct: 173 PSLESCDSSKFTC-LSGLSSSPTRCR--DYQEIKIQEQVQRLSVGSIPRSMKVILEDDLV 229

Query: 251 ERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTSGLRPFTA 310
           +    G  +T+ GI  +++     ++ R +  + ++++Y++ V      G+   +     
Sbjct: 230 DSCKSGDDLTIYGIV-MQRWKPFQQDVRCEVEIVLKANYIQ-VNNEQSSGII--MDEEVQ 285

Query: 311 EEEEQFRRLAASPDIYER--IGKSIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGD 368
           +E E F     S     R  I  S+ P VFG   +K A+A +L GG ++    G   RG+
Sbjct: 286 KEFEDFWEYYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGE 345

Query: 369 INILLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAGL 408
            ++LL+GDPGT KSQ LK+  K+ P  V T+G GS++AG+
Sbjct: 346 SHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGI 385


>AL132874-4|CAI42606.1|  156|Homo sapiens protein ( Human DNA
           sequence from clone RP3-329L24 on chromosome
           6q22.1-22.33.om chromosome 14 of Homo sapiens (Human).
           ).
          Length = 156

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 35/77 (45%), Positives = 51/77 (66%)

Query: 332 SIAPSVFGAVDMKKAIACLLFGGSRKRLPDGLTRRGDINILLLGDPGTAKSQLLKFVEKV 391
           S+ P VFG   +K A+A +L GG ++    G   RG+ ++LL+GDPGT KSQ LK+  K+
Sbjct: 74  SLCPQVFGMYLVKLAVAMVLAGGIQRTDATGTRVRGESHLLLVGDPGTGKSQFLKYAAKI 133

Query: 392 APIGVYTSGKGSSAAGL 408
            P  V T+G GS++AG+
Sbjct: 134 TPRSVLTTGIGSTSAGI 150


>BC009398-1|AAH09398.1|  389|Homo sapiens MCM7 protein protein.
          Length = 389

 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 50/188 (26%), Positives = 82/188 (43%), Gaps = 15/188 (7%)

Query: 133 LRELKSETVSRLVKIPGIVISASGIKAKATKISIQCRSCRNVIPNLPVKPGLEGYVM--P 190
           +RE+++++V +LV + GIV   S +K K    +  C  C          P     +M   
Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208

Query: 191 RKCNTEQSGRPKCPLDPYFIIPDKCKCIDYQVLKLQEAPESIPQGEMPRHLTVYCDRTLC 250
           ++C T +SG         ++     + I +Q +K+QE  + +P G +PR +TV  +    
Sbjct: 209 QECQTNRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENT 262

Query: 251 ERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYL---RAVGLTAEEGVTSGLRP 307
               PG  V+V GI+    I + G     +G +    +YL   R V +   E   SG   
Sbjct: 263 RIAQPGDHVSVTGIF--LPILRTGFRQVVQGLLS--ETYLEAHRIVKMNKSEDDESGAGE 318

Query: 308 FTAEEEEQ 315
            T EE  Q
Sbjct: 319 LTREELRQ 326


>BC093974-1|AAH93974.1|  584|Homo sapiens epsin 2 protein.
          Length = 584

 Score = 34.7 bits (76), Expect = 1.1
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 244 YCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTS 303
           Y  +T  ERVA   R  +  I ++K    + R+G+D+G + VR    + V L  +E    
Sbjct: 83  YLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG-INVREKSKQLVALLKDEERLK 141

Query: 304 GLRPFTAEEEEQFRRLA 320
             R    + +E+  ++A
Sbjct: 142 AERAQALKTKERMAQVA 158


>BC093972-1|AAH93972.1|  584|Homo sapiens epsin 2 protein.
          Length = 584

 Score = 34.7 bits (76), Expect = 1.1
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 244 YCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTS 303
           Y  +T  ERVA   R  +  I ++K    + R+G+D+G + VR    + V L  +E    
Sbjct: 83  YLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG-INVREKSKQLVALLKDEERLK 141

Query: 304 GLRPFTAEEEEQFRRLA 320
             R    + +E+  ++A
Sbjct: 142 AERAQALKTKERMAQVA 158


>AK024115-1|BAB14831.1|  371|Homo sapiens protein ( Homo sapiens
           cDNA FLJ14053 fis, clone HEMBA1007174, highly similar to
           Homo sapiens epsin 2b mRNA. ).
          Length = 371

 Score = 34.7 bits (76), Expect = 1.1
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 244 YCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTS 303
           Y  +T  ERVA   R  +  I ++K    + R+G+D+G + VR    + V L  +E    
Sbjct: 44  YLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG-INVREKSKQLVALLKDEERLK 102

Query: 304 GLRPFTAEEEEQFRRLA 320
             R    + +E+  ++A
Sbjct: 103 AERAQALKTKERMAQVA 119


>AF062085-1|AAC78609.1|  642|Homo sapiens epsin 2b protein.
          Length = 642

 Score = 34.7 bits (76), Expect = 1.1
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 244 YCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTS 303
           Y  +T  ERVA   R  +  I ++K    + R+G+D+G + VR    + V L  +E    
Sbjct: 83  YLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG-INVREKSKQLVALLKDEERLK 141

Query: 304 GLRPFTAEEEEQFRRLA 320
             R    + +E+  ++A
Sbjct: 142 AERAQALKTKERMAQVA 158


>AF062084-1|AAC78608.1|  584|Homo sapiens epsin 2a protein.
          Length = 584

 Score = 34.7 bits (76), Expect = 1.1
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 244 YCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTS 303
           Y  +T  ERVA   R  +  I ++K    + R+G+D+G + VR    + V L  +E    
Sbjct: 83  YLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG-INVREKSKQLVALLKDEERLK 141

Query: 304 GLRPFTAEEEEQFRRLA 320
             R    + +E+  ++A
Sbjct: 142 AERAQALKTKERMAQVA 158


>AB028988-1|BAA83017.2|  665|Homo sapiens KIAA1065 protein protein.
          Length = 665

 Score = 34.7 bits (76), Expect = 1.1
 Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 1/77 (1%)

Query: 244 YCDRTLCERVAPGARVTVLGIYSIKKIAKVGREGRDKGSVGVRSSYLRAVGLTAEEGVTS 303
           Y  +T  ERVA   R  +  I ++K    + R+G+D+G + VR    + V L  +E    
Sbjct: 107 YLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQG-INVREKSKQLVALLKDEERLK 165

Query: 304 GLRPFTAEEEEQFRRLA 320
             R    + +E+  ++A
Sbjct: 166 AERAQALKTKERMAQVA 182


>BC041613-1|AAH41613.1|  348|Homo sapiens transcription elongation
           factor A (SII), 3 protein.
          Length = 348

 Score = 32.7 bits (71), Expect = 4.4
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)

Query: 414 RDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTI---SIAKAGITT 470
           R+PG R  V+ G        G++     ++M  D+   +  AM Q+ I    +AK G TT
Sbjct: 249 RNPGLRRNVLSGAI----SAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTT 304

Query: 471 TLNSRCSVLAAANSVFGRWDDTKADD 496
           T   +CS     N  + +     AD+
Sbjct: 305 TDLFQCSKCKKKNCTYNQVQTRSADE 330


>AL357134-3|CAI22178.1|  348|Homo sapiens transcription elongation
           factor A (SII), 3 protein.
          Length = 348

 Score = 32.7 bits (71), Expect = 4.4
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)

Query: 414 RDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTI---SIAKAGITT 470
           R+PG R  V+ G        G++     ++M  D+   +  AM Q+ I    +AK G TT
Sbjct: 249 RNPGLRRNVLSGAI----SAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTT 304

Query: 471 TLNSRCSVLAAANSVFGRWDDTKADD 496
           T   +CS     N  + +     AD+
Sbjct: 305 TDLFQCSKCKKKNCTYNQVQTRSADE 330


>AL109936-2|CAI19025.1|  348|Homo sapiens transcription elongation
           factor A (SII), 3 protein.
          Length = 348

 Score = 32.7 bits (71), Expect = 4.4
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)

Query: 414 RDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTI---SIAKAGITT 470
           R+PG R  V+ G        G++     ++M  D+   +  AM Q+ I    +AK G TT
Sbjct: 249 RNPGLRRNVLSGAI----SAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTT 304

Query: 471 TLNSRCSVLAAANSVFGRWDDTKADD 496
           T   +CS     N  + +     AD+
Sbjct: 305 TDLFQCSKCKKKNCTYNQVQTRSADE 330


>AJ223473-1|CAA11393.1|  320|Homo sapiens transcription elongation
           factor TFIIS.h protein.
          Length = 320

 Score = 32.7 bits (71), Expect = 4.4
 Identities = 24/86 (27%), Positives = 38/86 (44%), Gaps = 7/86 (8%)

Query: 414 RDPGSRNFVMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTI---SIAKAGITT 470
           R+PG R  V+ G        G++     ++M  D+   +  AM Q+ I    +AK G TT
Sbjct: 221 RNPGLRRNVLSGAI----SAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTT 276

Query: 471 TLNSRCSVLAAANSVFGRWDDTKADD 496
           T   +CS     N  + +     AD+
Sbjct: 277 TDLFQCSKCKKKNCTYNQVQTRSADE 302


>Y08768-1|CAA70021.1|  380|Homo sapiens IL-13 receptor protein.
          Length = 380

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 437 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTL----NSRCSVLAAANSVFGRWDDT 492
           C D   ++REDD   +   +E +T ++     T  L     S+ ++  + + ++  W D 
Sbjct: 269 CFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDK 328

Query: 493 KADDNIDFMPTILSRFDMIF 512
           +  +  D     L RF + F
Sbjct: 329 QCWEGEDLSKKTLLRFWLPF 348


>X95302-1|CAA64617.1|  380|Homo sapiens interleukin 13 receptor
           protein.
          Length = 380

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 437 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTL----NSRCSVLAAANSVFGRWDDT 492
           C D   ++REDD   +   +E +T ++     T  L     S+ ++  + + ++  W D 
Sbjct: 269 CFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDK 328

Query: 493 KADDNIDFMPTILSRFDMIF 512
           +  +  D     L RF + F
Sbjct: 329 QCWEGEDLSKKTLLRFWLPF 348


>U70981-1|AAB17170.1|  380|Homo sapiens interleukin-13 receptor
           protein.
          Length = 380

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 437 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTL----NSRCSVLAAANSVFGRWDDT 492
           C D   ++REDD   +   +E +T ++     T  L     S+ ++  + + ++  W D 
Sbjct: 269 CFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDK 328

Query: 493 KADDNIDFMPTILSRFDMIF 512
           +  +  D     L RF + F
Sbjct: 329 QCWEGEDLSKKTLLRFWLPF 348


>BC126472-1|AAI26473.1|  452|Homo sapiens tripartite
           motif-containing 49 protein.
          Length = 452

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 20  NESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYR-DALKRNY-NLNQYWVEINIEDLSSFD 77
           +E + H NL+ +KKK KE   + H       +R + L+  Y  LN+   + ++E L +F 
Sbjct: 191 HEEEKH-NLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFG 249

Query: 78  DVL 80
           D+L
Sbjct: 250 DIL 252


>BC126470-1|AAI26471.1|  452|Homo sapiens tripartite
           motif-containing 49 protein.
          Length = 452

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 20  NESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYR-DALKRNY-NLNQYWVEINIEDLSSFD 77
           +E + H NL+ +KKK KE   + H       +R + L+  Y  LN+   + ++E L +F 
Sbjct: 191 HEEEKH-NLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFG 249

Query: 78  DVL 80
           D+L
Sbjct: 250 DIL 252


>BC075020-1|AAH75020.1|  452|Homo sapiens ring finger protein 18
           protein.
          Length = 452

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 20  NESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYR-DALKRNY-NLNQYWVEINIEDLSSFD 77
           +E + H NL+ +KKK KE   + H       +R + L+  Y  LN+   + ++E L +F 
Sbjct: 191 HEEEKH-NLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFG 249

Query: 78  DVL 80
           D+L
Sbjct: 250 DIL 252


>BC075019-1|AAH75019.1|  452|Homo sapiens tripartite
           motif-containing 49 protein.
          Length = 452

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 20  NESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYR-DALKRNY-NLNQYWVEINIEDLSSFD 77
           +E + H NL+ +KKK KE   + H       +R + L+  Y  LN+   + ++E L +F 
Sbjct: 191 HEEEKH-NLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFG 249

Query: 78  DVL 80
           D+L
Sbjct: 250 DIL 252


>BC033705-1|AAH33705.1|  380|Homo sapiens interleukin 13 receptor,
           alpha 2 protein.
          Length = 380

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 437 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTL----NSRCSVLAAANSVFGRWDDT 492
           C D   ++REDD   +   +E +T ++     T  L     S+ ++  + + ++  W D 
Sbjct: 269 CFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDK 328

Query: 493 KADDNIDFMPTILSRFDMIF 512
           +  +  D     L RF + F
Sbjct: 329 QCWEGEDLSKKTLLRFWLPF 348


>BC020739-1|AAH20739.1|  380|Homo sapiens interleukin 13 receptor,
           alpha 2 protein.
          Length = 380

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 437 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTL----NSRCSVLAAANSVFGRWDDT 492
           C D   ++REDD   +   +E +T ++     T  L     S+ ++  + + ++  W D 
Sbjct: 269 CFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDK 328

Query: 493 KADDNIDFMPTILSRFDMIF 512
           +  +  D     L RF + F
Sbjct: 329 QCWEGEDLSKKTLLRFWLPF 348


>AY656702-1|AAT49099.1|  380|Homo sapiens interleukin 13 receptor,
           alpha 2 protein.
          Length = 380

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 437 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTL----NSRCSVLAAANSVFGRWDDT 492
           C D   ++REDD   +   +E +T ++     T  L     S+ ++  + + ++  W D 
Sbjct: 269 CFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDK 328

Query: 493 KADDNIDFMPTILSRFDMIF 512
           +  +  D     L RF + F
Sbjct: 329 QCWEGEDLSKKTLLRFWLPF 348


>AL121878-1|CAD18962.1|  380|Homo sapiens interleukin 13 receptor,
           alpha 2 protein.
          Length = 380

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 18/80 (22%), Positives = 35/80 (43%), Gaps = 4/80 (5%)

Query: 437 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTL----NSRCSVLAAANSVFGRWDDT 492
           C D   ++REDD   +   +E +T ++     T  L     S+ ++  + + ++  W D 
Sbjct: 269 CFDYEIEIREDDTTLVTATVENETYTLKTTNETRQLCFVVRSKVNIYCSDDGIWSEWSDK 328

Query: 493 KADDNIDFMPTILSRFDMIF 512
           +  +  D     L RF + F
Sbjct: 329 QCWEGEDLSKKTLLRFWLPF 348


>AB037682-1|BAB03503.1|  452|Homo sapiens testis-specific RING
           Finger protein protein.
          Length = 452

 Score = 31.9 bits (69), Expect = 7.6
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 20  NESQDHVNLQAVKKKFKEFMRQFHTGNFNYKYR-DALKRNY-NLNQYWVEINIEDLSSFD 77
           +E + H NL+ +KKK KE   + H       +R + L+  Y  LN+   + ++E L +F 
Sbjct: 191 HEEEKH-NLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFG 249

Query: 78  DVL 80
           D+L
Sbjct: 250 DIL 252


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.319    0.136    0.388 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,277,661
Number of Sequences: 224733
Number of extensions: 3691589
Number of successful extensions: 7455
Number of sequences better than 10.0: 82
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 7172
Number of HSP's gapped (non-prelim): 158
length of query: 675
length of database: 73,234,838
effective HSP length: 95
effective length of query: 580
effective length of database: 51,885,203
effective search space: 30093417740
effective search space used: 30093417740
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 69 (31.9 bits)