Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005129-TA|BGIBMGA005129-PA|IPR013273|ADAM-TS,
IPR002223|Proteinase inhibitor I2, Kunitz metazoa,
IPR000884|Thrombospondin, type I, IPR010294|ADAM-TS Spacer 1
(2102 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr... 388 e-107
AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein. 385 e-106
AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein. 372 e-102
AB209685-1|BAD92922.1| 530|Homo sapiens a disintegrin and metal... 361 1e-98
BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase w... 359 8e-98
AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disinte... 334 3e-90
AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptida... 332 1e-89
BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase w... 327 2e-88
AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein. 327 2e-88
AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and ... 326 4e-88
AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein. 320 3e-86
AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and ... 305 8e-82
AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein. 301 1e-80
AB209515-1|BAD92752.1| 847|Homo sapiens a disintegrin-like and ... 301 2e-80
AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and ... 295 8e-79
AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein. 291 2e-77
AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein. 291 2e-77
BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase w... 291 2e-77
AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein. 291 2e-77
AL356356-13|CAI15500.2| 1074|Homo sapiens ADAMTS-like 4 protein. 289 5e-77
AF140674-1|AAD56357.1| 860|Homo sapiens zinc metalloprotease AD... 276 7e-73
AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin metalloprot... 272 9e-72
BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein. 256 6e-67
BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase w... 256 6e-67
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 255 1e-66
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 254 3e-66
AF237652-1|AAK15041.1| 766|Homo sapiens a disintegrin-like and ... 252 8e-66
AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein. 252 1e-65
AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-protein... 252 1e-65
AK131414-1|BAD18561.1| 493|Homo sapiens protein ( Homo sapiens ... 250 3e-65
AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein. 245 1e-63
AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and ... 245 1e-63
AL358817-5|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase w... 244 2e-63
AL358817-4|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase w... 244 2e-63
AL355344-5|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase w... 244 2e-63
AL355344-4|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase w... 244 2e-63
AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disinte... 235 2e-60
AY358122-1|AAQ88489.1| 877|Homo sapiens ENWT2803 protein. 233 5e-60
AL356356-12|CAI15499.1| 877|Homo sapiens ADAMTS-like 4 protein. 233 5e-60
AF176313-1|AAK84170.1| 525|Homo sapiens ADAM-TS related protein... 222 9e-57
BC036515-1|AAH36515.1| 967|Homo sapiens ADAM metallopeptidase w... 221 3e-56
AP001697-1|BAA95502.1| 967|Homo sapiens metalloprotease with th... 221 3e-56
AL162080-1|CAB82413.1| 550|Homo sapiens hypothetical protein pr... 221 3e-56
AF207664-1|AAF23772.1| 967|Homo sapiens matrix metalloprotease ... 221 3e-56
AF170084-1|AAF15317.1| 967|Homo sapiens metalloproteinase with ... 221 3e-56
AF060152-1|AAD48080.1| 950|Homo sapiens METH1 protein protein. 221 3e-56
AB037767-1|BAA92584.1| 999|Homo sapiens KIAA1346 protein protein. 221 3e-56
AL353895-1|CAI14851.1| 525|Homo sapiens ADAMTS-like 1 protein. 220 5e-56
AY358327-1|AAQ88693.1| 525|Homo sapiens ADAMTSL1 protein. 219 9e-56
BC030262-1|AAH30262.1| 439|Homo sapiens ADAMTS-like 1 protein. 218 2e-55
AK023772-1|BAB14673.1| 538|Homo sapiens protein ( Homo sapiens ... 213 4e-54
AB209717-1|BAD92954.1| 418|Homo sapiens ADAMTS-8 precursor vari... 201 2e-50
BC089435-1|AAH89435.1| 918|Homo sapiens ADAMTS8 protein protein. 200 4e-50
AF060153-1|AAD48081.1| 890|Homo sapiens METH2 protein protein. 200 4e-50
BC094811-1|AAH94811.1| 602|Homo sapiens ADAMTSL4 protein protein. 199 1e-49
BC071852-1|AAH71852.1| 602|Homo sapiens ADAMTSL4 protein protein. 199 1e-49
BC027478-1|AAH27478.1| 424|Homo sapiens ADAMTSL4 protein protein. 199 1e-49
AY358118-1|AAQ88485.1| 1097|Homo sapiens ADAMTS13 protein. 198 2e-49
DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase w... 196 5e-49
AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase ... 196 5e-49
AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase ... 196 5e-49
AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase w... 196 5e-49
AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase ... 196 5e-49
AL158826-23|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase ... 196 5e-49
AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase ... 196 5e-49
AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, vari... 196 5e-49
AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein. 196 5e-49
AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein. 196 5e-49
AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand factor-c... 196 5e-49
AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand factor-c... 196 7e-49
BC113874-1|AAI13875.1| 676|Homo sapiens ADAMTS8 protein protein. 195 1e-48
AK131551-1|BAD18685.1| 577|Homo sapiens protein ( Homo sapiens ... 194 3e-48
BX649571-2|CAI18773.1| 951|Homo sapiens ADAMTS-like 2 protein. 193 7e-48
BX649571-1|CAM26559.1| 1060|Homo sapiens ADAMTS-like 2 protein. 193 7e-48
BX629352-2|CAI23592.1| 951|Homo sapiens ADAMTS-like 2 protein. 193 7e-48
BX629352-1|CAM28356.1| 1060|Homo sapiens ADAMTS-like 2 protein. 193 7e-48
BX324209-2|CAI17317.1| 951|Homo sapiens ADAMTS-like 2 protein. 193 7e-48
BX324209-1|CAM24586.1| 1060|Homo sapiens ADAMTS-like 2 protein. 193 7e-48
BC050544-1|AAH50544.1| 951|Homo sapiens ADAMTS-like 2 protein. 193 7e-48
AB011177-1|BAA25531.2| 1031|Homo sapiens KIAA0605 protein protein. 193 7e-48
BX641106-1|CAE46049.1| 321|Homo sapiens hypothetical protein pr... 188 2e-46
AK131403-1|BAD18550.1| 415|Homo sapiens protein ( Homo sapiens ... 187 4e-46
AY358886-1|AAQ89245.1| 837|Homo sapiens ADAMTS4 protein. 183 7e-45
AL590714-6|CAH72146.1| 837|Homo sapiens ADAM metallopeptidase w... 183 7e-45
AF148213-1|AAD41494.1| 837|Homo sapiens aggrecanase-1 protein. 183 7e-45
AB014588-1|BAA31663.2| 849|Homo sapiens KIAA0688 protein protein. 183 7e-45
BC040620-1|AAH40620.1| 356|Homo sapiens ADAMTSL5 protein protein. 182 1e-44
AK131571-1|BAD18703.1| 471|Homo sapiens protein ( Homo sapiens ... 182 2e-44
BC063293-1|AAH63293.1| 837|Homo sapiens ADAM metallopeptidase w... 180 5e-44
BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein. 180 7e-44
AY044847-1|AAL02262.1| 837|Homo sapiens aggrecanase 1 protein. 180 7e-44
BC109114-1|AAI09115.1| 950|Homo sapiens ADAM metallopeptidase w... 173 6e-42
AJ315733-1|CAC86014.1| 950|Homo sapiens metalloprotease disinte... 173 6e-42
AF140675-1|AAD56358.1| 997|Homo sapiens zinc metalloprotease AD... 173 6e-42
AK092324-1|BAC03862.1| 296|Homo sapiens protein ( Homo sapiens ... 166 7e-40
AF141293-1|AAF02493.1| 518|Homo sapiens ADAMTS5 protein protein. 164 3e-39
BC093777-1|AAH93777.1| 930|Homo sapiens ADAM metallopeptidase w... 163 5e-39
BC093775-1|AAH93775.1| 930|Homo sapiens ADAM metallopeptidase w... 163 5e-39
AY172951-1|AAO45695.1| 387|Homo sapiens disintegrin and metallo... 163 5e-39
AF142099-1|AAD49577.1| 930|Homo sapiens aggrecanase-2 protein. 163 5e-39
AP001697-2|BAA95503.1| 517|Homo sapiens disintegrin-like and me... 162 1e-38
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 157 5e-37
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 157 5e-37
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 157 5e-37
AK122677-1|BAC85503.1| 375|Homo sapiens protein ( Homo sapiens ... 151 2e-35
DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase w... 139 1e-31
AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disinte... 139 1e-31
L27624-1|AAA20094.1| 235|Homo sapiens tissue factor pathway inh... 136 1e-30
D29992-1|BAA06272.1| 235|Homo sapiens placental protein 5 (PP5)... 136 1e-30
BC005330-1|AAH05330.1| 235|Homo sapiens tissue factor pathway i... 136 1e-30
AY691946-1|AAU04568.1| 235|Homo sapiens tissue factor pathway i... 136 1e-30
AK023228-1|BAB14479.1| 622|Homo sapiens protein ( Homo sapiens ... 136 1e-30
AF217542-1|AAK13254.1| 235|Homo sapiens tissue factor pathway i... 136 1e-30
AC002076-1|AAS02022.1| 235|Homo sapiens unknown protein. 136 1e-30
AY692423-1|AAW47396.1| 270|Homo sapiens ADAMTS6 variant 2 protein. 135 2e-30
AK092499-1|BAC03906.1| 224|Homo sapiens rase. protein. 130 4e-29
AK128469-1|BAC87455.1| 327|Homo sapiens protein ( Homo sapiens ... 129 9e-29
AK131344-1|BAD18500.1| 502|Homo sapiens protein ( Homo sapiens ... 128 2e-28
M59499-1|AAA59526.1| 304|Homo sapiens lipoprotein-associated co... 120 4e-26
M58650-1|AAA59480.1| 304|Homo sapiens lipoprotein associated co... 120 4e-26
J03225-1|AAA52022.1| 304|Homo sapiens TFPI protein. 120 4e-26
AY263365-1|AAO89075.1| 304|Homo sapiens tissue factor pathway i... 120 4e-26
AC007319-2|AAY14807.1| 304|Homo sapiens unknown protein. 120 4e-26
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 120 6e-26
BC100788-1|AAI00789.1| 467|Homo sapiens C9orf94 protein protein. 119 1e-25
BC100790-1|AAI00791.1| 284|Homo sapiens C9orf94 protein protein. 119 1e-25
BC016451-1|AAH16451.1| 364|Homo sapiens ADAMTS3 protein protein. 118 2e-25
AK131039-1|BAC85480.1| 288|Homo sapiens protein ( Homo sapiens ... 118 2e-25
AJ011374-1|CAB66157.1| 364|Homo sapiens hypothetical protein pr... 116 9e-25
AL359934-1|CAB95770.1| 432|Homo sapiens ADAMTS7, alternatively ... 111 3e-23
AY358142-1|AAQ88509.1| 576|Homo sapiens Bikunin hlg protein. 110 6e-23
AF468657-1|AAL77058.1| 576|Homo sapiens multivalent protease in... 110 6e-23
X54818-1|CAA38587.1| 151|Homo sapiens bikunin protein. 109 8e-23
X54816-1|CAA38585.1| 352|Homo sapiens bikunin protein. 109 8e-23
X04494-1|CAA28182.1| 352|Homo sapiens protein ( Human mRNA for ... 109 8e-23
X04225-1|CAA27803.1| 352|Homo sapiens HC polypeptide protein. 109 8e-23
M88249-1|AAA59196.1| 352|Homo sapiens inter-alpha-trypsin inhib... 109 8e-23
BC041593-1|AAH41593.1| 352|Homo sapiens alpha-1-microglobulin/b... 109 8e-23
AY544123-1|AAT11154.1| 352|Homo sapiens growth-inhibiting prote... 109 8e-23
AL137850-4|CAI15899.1| 352|Homo sapiens alpha-1-microglobulin/b... 109 8e-23
Z84479-2|CAM26437.1| 548|Homo sapiens WAP, follistatin/kazal, i... 108 2e-22
BC101606-1|AAI01607.1| 548|Homo sapiens WAP, follistatin/kazal,... 108 2e-22
BC101602-1|AAI01603.1| 548|Homo sapiens WAP, follistatin/kazal,... 108 2e-22
AF422194-1|AAL18839.1| 548|Homo sapiens putative multivalent pr... 108 2e-22
AE006464-5|AAK61237.1| 491|Homo sapiens unknown protein. 108 2e-22
BC015514-1|AAH15514.1| 251|Homo sapiens tissue factor pathway i... 106 7e-22
AF021834-1|AAD01700.1| 251|Homo sapiens tissue factor pathway i... 106 7e-22
AB209866-1|BAD93103.1| 201|Homo sapiens tissue factor pathway i... 106 7e-22
AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein. 103 7e-21
BC042057-1|AAH42057.1| 129|Homo sapiens PAPLN protein protein. 102 1e-20
AF217974-1|AAG17217.1| 237|Homo sapiens unknown protein. 102 2e-20
AB023177-1|BAA76804.2| 1502|Homo sapiens KIAA0960 protein protein. 102 2e-20
BC034155-1|AAH34155.1| 167|Homo sapiens Similar to tissue facto... 98 3e-19
BT007425-1|AAP36093.1| 513|Homo sapiens serine protease inhibit... 96 1e-18
BC018702-1|AAH18702.1| 513|Homo sapiens serine peptidase inhibi... 96 1e-18
BC004140-1|AAH04140.1| 513|Homo sapiens serine peptidase inhibi... 96 1e-18
AB000095-1|BAA25014.1| 513|Homo sapiens hepatocyte growth facto... 96 1e-18
AK131196-1|BAD18391.1| 283|Homo sapiens protein ( Homo sapiens ... 93 1e-17
AY358969-1|AAQ89328.1| 529|Homo sapiens HAI-1 protein. 91 3e-17
AY296715-1|AAP44001.1| 529|Homo sapiens hepatocyte growth facto... 91 3e-17
AF027205-1|AAB84031.1| 252|Homo sapiens Kunitz-type protease in... 90 7e-17
U78095-1|AAC02781.1| 252|Homo sapiens bikunin protein. 89 2e-16
CR407604-1|CAG28532.1| 252|Homo sapiens SPINT2 protein. 89 2e-16
BT020117-1|AAV38920.1| 252|Homo sapiens serine protease inhibit... 89 2e-16
BT020116-1|AAV38919.1| 252|Homo sapiens serine protease inhibit... 89 2e-16
BT020115-1|AAV38918.1| 252|Homo sapiens serine protease inhibit... 89 2e-16
BC012868-1|AAH12868.1| 252|Homo sapiens serine peptidase inhibi... 89 2e-16
BC011955-1|AAH11955.1| 252|Homo sapiens serine peptidase inhibi... 89 2e-16
BC011951-1|AAH11951.1| 252|Homo sapiens serine peptidase inhibi... 89 2e-16
BC007705-1|AAH07705.1| 252|Homo sapiens serine peptidase inhibi... 89 2e-16
BC001668-1|AAH01668.1| 252|Homo sapiens serine peptidase inhibi... 89 2e-16
AB006534-1|BAA25024.1| 252|Homo sapiens hepatocyte growth facto... 89 2e-16
AL353895-4|CAI14853.2| 470|Homo sapiens ADAMTS-like 1 protein. 87 6e-16
AF251058-1|AAK34948.1| 417|Homo sapiens thrombospondin protein. 87 6e-16
AB051466-1|BAB21770.1| 1536|Homo sapiens KIAA1679 protein protein. 87 6e-16
BC033125-1|AAH33125.1| 740|Homo sapiens THSD7B protein protein. 83 8e-15
BC019344-1|AAH19344.1| 740|Homo sapiens THSD7B protein protein. 83 8e-15
X52022-1|CAA36267.1| 3176|Homo sapiens collagen type VI, alpha 3... 81 3e-14
BX641155-1|CAE46068.1| 558|Homo sapiens hypothetical protein pr... 81 3e-14
BC033174-1|AAH33174.1| 979|Homo sapiens Similar to collagen, ty... 81 3e-14
AC112715-1|AAY14906.1| 588|Homo sapiens unknown protein. 81 3e-14
AB209636-1|BAD92873.1| 1702|Homo sapiens alpha 3 type VI collage... 81 3e-14
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 77 5e-13
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 77 5e-13
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 77 5e-13
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 77 5e-13
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 77 5e-13
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 77 5e-13
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 77 5e-13
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 77 5e-13
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 77 5e-13
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 77 5e-13
BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein pr... 76 2e-12
AB051390-1|BAB18461.1| 807|Homo sapiens VSGP/F-spondin protein. 74 6e-12
AB018305-1|BAA34482.2| 724|Homo sapiens KIAA0762 protein protein. 74 6e-12
X06989-1|CAA30050.1| 751|Homo sapiens amyloid A4 protein protein. 72 2e-11
X06982-1|CAA30042.1| 62|Homo sapiens amyloid beta-protein prot... 72 2e-11
X06981-1|CAA30041.1| 81|Homo sapiens protein ( Human mRNA frag... 72 2e-11
M34875-1|AAB59501.1| 547|Homo sapiens amyloid-beta protein prot... 72 2e-11
M33112-1|AAB59502.1| 770|Homo sapiens amyloid-beta protein prot... 72 2e-11
M28373-1|AAA58727.1| 484|Homo sapiens amyloid precursor protein... 72 2e-11
D87675-1|BAA22264.1| 770|Homo sapiens amyloid precursor protein... 72 2e-11
BC065529-1|AAH65529.1| 751|Homo sapiens amyloid beta (A4) precu... 72 2e-11
AY919674-1|AAW82435.1| 770|Homo sapiens amyloid beta (A4) precu... 72 2e-11
L23982-1|AAA58965.1| 2912|Homo sapiens collagen type VII protein. 72 3e-11
L06862-1|AAA89196.1| 550|Homo sapiens type VII collagen protein. 72 3e-11
L02870-1|AAA75438.1| 2944|Homo sapiens alpha-1 type VII collagen... 72 3e-11
EF488667-1|ABP02055.1| 95|Homo sapiens TFPI2 variant protein. 72 3e-11
BC053369-1|AAH53369.1| 133|Homo sapiens serine peptidase inhibi... 72 3e-11
BC044829-1|AAH44829.2| 133|Homo sapiens serine peptidase inhibi... 72 3e-11
AL118493-1|CAB56343.1| 133|Homo sapiens hypothetical protein pr... 72 3e-11
AL031663-12|CAB37635.1| 133|Homo sapiens serine peptidase inhib... 72 3e-11
AL031663-11|CAC36265.1| 117|Homo sapiens serine peptidase inhib... 72 3e-11
AF286370-1|AAG00548.1| 133|Homo sapiens eppin-3 protein. 72 3e-11
AF286369-1|AAG00547.1| 117|Homo sapiens eppin-2 protein. 72 3e-11
AF286368-1|AAG00546.1| 133|Homo sapiens eppin-1 protein. 72 3e-11
X77166-1|CAA54410.1| 64|Homo sapiens Kunitz-type protease inhi... 71 3e-11
AL031663-6|CAB37639.3| 89|Homo sapiens serine peptidase inhibi... 71 3e-11
AK074803-1|BAC11217.1| 807|Homo sapiens protein ( Homo sapiens ... 71 5e-11
BC065523-1|AAH65523.1| 352|Homo sapiens APP protein protein. 70 1e-10
AB005297-1|BAA23647.1| 1584|Homo sapiens BAI 1 protein. 68 3e-10
Z22572-1|CAA80295.1| 763|Homo sapiens CDEI binding protein prot... 65 2e-09
S60099-1|AAC60589.1| 763|Homo sapiens APPH protein. 65 2e-09
L27631-1|AAC41701.1| 763|Homo sapiens amyloid precursor-like pr... 65 2e-09
L23113-1|AAA36032.1| 523|Homo sapiens binding protein protein. 65 2e-09
L09209-1|AAA35526.1| 763|Homo sapiens amyloid protein protein. 65 2e-09
BC000373-1|AAH00373.1| 751|Homo sapiens APLP2 protein protein. 65 2e-09
AF168956-1|AAD47291.1| 763|Homo sapiens amyloid precursor prote... 65 2e-09
AJ890451-1|CAI67595.1| 1125|Homo sapiens collagen, type XXVIII p... 64 4e-09
AL354919-5|CAI16890.1| 1584|Homo sapiens brain-specific angiogen... 63 1e-08
AL354919-2|CAM12875.1| 1554|Homo sapiens brain-specific angiogen... 63 1e-08
AK128724-1|BAC87592.1| 160|Homo sapiens protein ( Homo sapiens ... 63 1e-08
AB065648-1|BAC05874.1| 1573|Homo sapiens seven transmembrane hel... 63 1e-08
AB005298-1|BAA25362.1| 1572|Homo sapiens BAI 2 protein. 63 1e-08
AL591715-1|CAC39449.1| 232|Homo sapiens hypothetical protein pr... 62 2e-08
AL121778-2|CAI22977.1| 241|Homo sapiens WAP four-disulfide core... 62 2e-08
AL031663-1|CAI21403.1| 241|Homo sapiens WAP four-disulfide core... 62 2e-08
AF492016-1|AAN70998.1| 241|Homo sapiens probable protease inhib... 62 2e-08
AF492015-1|AAN70997.1| 241|Homo sapiens probable protease inhib... 62 2e-08
AY372172-1|AAR17081.1| 69|Homo sapiens serine protease inhibit... 59 1e-07
L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein. 59 2e-07
BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein. 59 2e-07
AL391807-1|CAI21673.1| 1522|Homo sapiens brain-specific angiogen... 58 3e-07
AL359714-1|CAH71522.1| 1522|Homo sapiens brain-specific angiogen... 58 3e-07
AL356117-1|CAH71772.1| 1522|Homo sapiens brain-specific angiogen... 58 3e-07
AL160401-1|CAH73864.1| 1522|Homo sapiens brain-specific angiogen... 58 3e-07
AL158051-1|CAI19625.1| 1522|Homo sapiens brain-specific angiogen... 58 3e-07
AL133378-1|CAC34969.2| 1522|Homo sapiens brain-specific angiogen... 58 3e-07
BC111720-1|AAI11721.1| 1522|Homo sapiens brain-specific angiogen... 56 1e-06
AB011122-1|BAA25476.2| 1524|Homo sapiens KIAA0550 protein protein. 56 1e-06
AB005299-1|BAA25363.1| 1522|Homo sapiens BAI 3 protein. 56 1e-06
X14787-1|CAA32889.1| 1170|Homo sapiens precursor polypeptide (AA... 56 1e-06
X04665-1|CAA28370.1| 1170|Homo sapiens protein ( Human mRNA for ... 56 1e-06
AB209912-1|BAD93149.1| 1225|Homo sapiens thrombospondin 1 precur... 56 1e-06
BC041974-1|AAH41974.1| 257|Homo sapiens SPON1 protein protein. 56 2e-06
AK129873-1|BAC85245.1| 226|Homo sapiens protein ( Homo sapiens ... 56 2e-06
BC077726-1|AAH77726.1| 1151|Homo sapiens sema domain, seven thro... 55 3e-06
BC019825-1|AAH19825.1| 259|Homo sapiens SPON1 protein protein. 55 3e-06
AL122085-1|CAB59258.1| 111|Homo sapiens hypothetical protein pr... 55 3e-06
AB040878-1|BAA95969.1| 1202|Homo sapiens KIAA1445 protein protein. 55 3e-06
AY358143-1|AAQ88510.1| 219|Homo sapiens FVSY9334 protein. 54 7e-06
AL354919-7|CAM12879.1| 1500|Homo sapiens brain-specific angiogen... 53 1e-05
AL354919-3|CAM12876.1| 1499|Homo sapiens brain-specific angiogen... 53 1e-05
M11562-1|AAA59194.1| 51|Homo sapiens inter-alpha-trypsin inhib... 52 2e-05
BC115696-1|AAI15697.1| 1074|Homo sapiens sema domain, seven thro... 52 2e-05
AL354919-4|CAM12877.1| 847|Homo sapiens brain-specific angiogen... 52 2e-05
AL354919-1|CAM12874.1| 1466|Homo sapiens brain-specific angiogen... 52 2e-05
AY358124-1|AAQ88491.1| 1092|Homo sapiens SEMA5B protein. 51 4e-05
U52840-1|AAC09473.1| 1074|Homo sapiens semaphorin F homolog prot... 51 5e-05
AY372174-1|AAR17083.1| 99|Homo sapiens serine protease inhibit... 51 5e-05
AY372173-1|AAR17082.1| 99|Homo sapiens serine protease inhibit... 51 5e-05
AL109656-2|CAC36025.2| 99|Homo sapiens serine peptidase inhibi... 51 5e-05
AL050348-2|CAC36104.1| 51|Homo sapiens chromosome 20 open read... 50 7e-05
D86864-1|BAA24070.1| 830|Homo sapiens acetyl LDL receptor protein. 46 0.001
D63483-1|BAA09770.1| 830|Homo sapiens KIAA0149 protein. 46 0.001
BC039735-1|AAH39735.1| 830|Homo sapiens scavenger receptor clas... 46 0.001
AB052948-1|BAC02694.1| 569|Homo sapiens SREC-3 protein. 46 0.001
AB052946-1|BAC02692.1| 830|Homo sapiens SREC protein. 46 0.001
DQ364570-1|ABC88384.1| 127|Homo sapiens ADAM metallopeptidase w... 46 0.002
X70872-1|CAA50220.1| 469|Homo sapiens properdin protein. 45 0.003
X57748-1|CAA40914.1| 469|Homo sapiens properdin protein. 45 0.003
M83652-1|AAA36489.1| 469|Homo sapiens complement omponent prope... 45 0.003
BC015756-1|AAH15756.1| 469|Homo sapiens complement factor prope... 45 0.003
AY297813-1|AAP43692.1| 469|Homo sapiens properdin P factor, com... 45 0.003
AL359513-1|CAH71657.1| 852|Homo sapiens thrombospondin, type I,... 45 0.003
AF005668-1|AAB62886.1| 469|Homo sapiens properdin protein. 45 0.003
AB044385-1|BAA96553.1| 852|Homo sapiens transmembrane molecule ... 45 0.003
AF005666-1|AAC51626.1| 469|Homo sapiens properdin protein. 44 0.004
BC084578-1|AAH84578.1| 719|Homo sapiens AGRN protein protein. 44 0.006
AL645608-12|CAI15575.2| 2045|Homo sapiens agrin protein. 44 0.006
AL009172-3|CAA15658.1| 454|Homo sapiens complement factor prope... 44 0.006
AF016903-1|AAC39776.1| 2026|Homo sapiens agrin precursor protein. 44 0.006
AB191264-1|BAD52440.1| 2045|Homo sapiens agrin protein. 44 0.006
BC139833-1|AAI39834.1| 240|Homo sapiens ADAMTSL5 protein protein. 44 0.008
BC119796-1|AAI19797.1| 131|Homo sapiens ADAMTSL5 protein protein. 44 0.008
AY358149-1|AAQ88516.1| 429|Homo sapiens THSD1 protein. 43 0.010
AK027344-1|BAB55049.1| 741|Homo sapiens protein ( Homo sapiens ... 43 0.010
AL353779-7|CAI20981.1| 114|Homo sapiens late cornified envelope... 43 0.014
AB111888-1|BAC98376.1| 1322|Homo sapiens KIAA2036 protein protein. 43 0.014
AF005664-1|AAB63279.1| 160|Homo sapiens properdin protein. 42 0.024
BC131820-1|AAI31821.1| 1976|Homo sapiens FRAS1 protein protein. 42 0.032
BC104233-1|AAI04234.1| 118|Homo sapiens late cornified envelope... 42 0.032
BC104232-1|AAI04233.1| 118|Homo sapiens late cornified envelope... 42 0.032
BC064487-1|AAH64487.1| 651|Homo sapiens FRAS1 protein protein. 42 0.032
BC052281-1|AAH52281.1| 651|Homo sapiens FRAS1 protein protein. 42 0.032
AL353779-8|CAI20982.1| 118|Homo sapiens late cornified envelope... 42 0.032
AL162596-1|CAI19550.1| 118|Homo sapiens late cornified envelope... 42 0.032
AK027833-1|BAB55399.1| 441|Homo sapiens protein ( Homo sapiens ... 42 0.032
AJ512501-1|CAD54734.1| 4007|Homo sapiens extracellular matrix pr... 42 0.032
AF005665-1|AAB63280.1| 469|Homo sapiens properdin protein. 41 0.042
BC030532-1|AAH30532.1| 855|Homo sapiens suppression of tumorige... 40 0.096
BC018146-1|AAH18146.1| 422|Homo sapiens ST14 protein protein. 40 0.096
BC005826-1|AAH05826.2| 526|Homo sapiens ST14 protein protein. 40 0.096
AF283256-1|AAG13949.1| 325|Homo sapiens serine protease SNC19 p... 40 0.096
AF133086-1|AAF00109.1| 855|Homo sapiens membrane-type serine pr... 40 0.096
AF118224-1|AAD42765.2| 855|Homo sapiens matriptase protein. 40 0.096
AF057145-1|AAG15395.1| 855|Homo sapiens serine protease TADG15 ... 40 0.096
AB030036-1|BAB20376.1| 855|Homo sapiens prostamin protein. 40 0.096
L00352-1|AAA56833.1| 860|Homo sapiens low density lipoprotein r... 40 0.13
BT007361-1|AAP36025.1| 860|Homo sapiens low density lipoprotein... 40 0.13
BC014514-1|AAH14514.1| 860|Homo sapiens low density lipoprotein... 40 0.13
AY324609-1|AAP72971.1| 860|Homo sapiens low density lipoprotein... 40 0.13
AY114155-1|AAM56036.1| 860|Homo sapiens low density lipoprotein... 40 0.13
AL031663-9|CAI21404.1| 161|Homo sapiens WAP four-disulfide core... 40 0.13
AF283408-1|AAL38109.1| 1537|Homo sapiens candidate tumor suppres... 40 0.13
AF217403-1|AAF24515.1| 837|Homo sapiens low density lipoprotein... 40 0.13
AF176832-1|AAF70379.1| 4599|Homo sapiens low density lipoprotein... 40 0.13
AC068195-1|AAX93243.1| 1126|Homo sapiens unknown protein. 40 0.13
AB209707-1|BAD92944.1| 1720|Homo sapiens low density lipoprotein... 40 0.13
AB209409-1|BAD92646.1| 870|Homo sapiens low density lipoprotein... 40 0.13
AL353779-6|CAI20980.1| 118|Homo sapiens late cornified envelope... 39 0.17
AF117899-1|AAF27280.1| 363|Homo sapiens LDLR-FUT fusion protein... 39 0.17
AK092602-1|BAC03925.1| 262|Homo sapiens protein ( Homo sapiens ... 38 0.39
X72177-1|CAA50994.1| 934|Homo sapiens complement component C6 p... 38 0.51
J05064-1|AAA51860.1| 934|Homo sapiens C6 protein. 38 0.51
J05024-1|AAA59668.1| 934|Homo sapiens completement component C6... 38 0.51
J04506-1|AAB59433.1| 491|Homo sapiens complement component C6 p... 38 0.51
BC035723-1|AAH35723.1| 934|Homo sapiens C6 protein protein. 38 0.51
AB126592-1|BAD02321.1| 934|Homo sapiens complement component 6 ... 38 0.51
U33837-1|AAB41649.1| 4655|Homo sapiens gp330 precursor protein. 37 0.68
AY265358-1|AAP88586.1| 4655|Homo sapiens glycoprotein receptor g... 37 0.68
AY265357-1|AAP88585.1| 4655|Homo sapiens glycoprotein receptor g... 37 0.68
AL513320-1|CAI14334.1| 1229|Homo sapiens multiple EGF-like-domai... 37 0.68
AL512413-3|CAH70834.1| 1229|Homo sapiens multiple EGF-like-domai... 37 0.68
AC007556-2|AAX88965.1| 3881|Homo sapiens unknown protein. 37 0.68
AB011539-1|BAA32467.2| 1246|Homo sapiens MEGF6 protein. 37 0.68
AY358351-1|AAQ88717.1| 945|Homo sapiens GARS1883 protein. 37 0.90
AY126437-1|AAM95701.1| 934|Homo sapiens transmembrane receptor ... 37 0.90
AL359832-2|CAI16738.1| 934|Homo sapiens unc-5 homolog B (C. ele... 37 0.90
AL359832-1|CAI16737.1| 945|Homo sapiens unc-5 homolog B (C. ele... 37 0.90
AL359384-3|CAI16090.1| 934|Homo sapiens unc-5 homolog B (C. ele... 37 0.90
AL359384-2|CAI16089.1| 945|Homo sapiens unc-5 homolog B (C. ele... 37 0.90
AB096256-1|BAC57998.1| 945|Homo sapiens p53-regulated receptor ... 37 0.90
AK126555-1|BAC86591.1| 159|Homo sapiens protein ( Homo sapiens ... 36 1.2
S76436-1|AAB21121.2| 507|Homo sapiens heparan sulfate proteogly... 36 1.6
BC130605-1|AAI30606.1| 110|Homo sapiens late cornified envelope... 36 1.6
BC130603-1|AAI30604.1| 110|Homo sapiens late cornified envelope... 36 1.6
AL139247-4|CAI21682.1| 110|Homo sapiens late cornified envelope... 36 1.6
AL353779-5|CAI20979.1| 118|Homo sapiens late cornified envelope... 35 2.7
AK075302-1|BAC11535.1| 587|Homo sapiens protein ( Homo sapiens ... 35 3.6
AB231860-1|BAE19678.1| 1640|Homo sapiens hypothetical protein pr... 34 4.8
BC037300-1|AAH37300.1| 399|Homo sapiens KIAA1737 protein. 34 6.3
AY358147-1|AAQ88514.1| 953|Homo sapiens UNC5D protein. 34 6.3
AL353779-1|CAI20975.1| 250|Homo sapiens chromosome 1 open readi... 34 6.3
AK056571-1|BAB71219.1| 955|Homo sapiens protein ( Homo sapiens ... 34 6.3
AF005081-1|AAB83961.1| 112|Homo sapiens skin-specific protein p... 34 6.3
AB055056-1|BAB83663.1| 948|Homo sapiens KIAA1777 protein (Unc5h... 34 6.3
AB051524-1|BAB21828.1| 400|Homo sapiens KIAA1737 protein protein. 34 6.3
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 33 8.4
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 33 8.4
M64283-1|AAA52699.1| 453|Homo sapiens heparan sulfate proteogly... 33 8.4
BC074841-1|AAH74841.1| 367|Homo sapiens WNT1 inducible signalin... 33 8.4
BC074840-1|AAH74840.1| 367|Homo sapiens WNT1 inducible signalin... 33 8.4
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 33 8.4
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 33 8.4
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 33 8.4
AJ628247-1|CAF31639.1| 221|Homo sapiens keratin associated prot... 33 8.4
AF100779-1|AAC96321.1| 367|Homo sapiens connective tissue growt... 33 8.4
AB126074-1|BAD20201.1| 221|Homo sapiens keratin associated prot... 33 8.4
>AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein
protein.
Length = 1235
Score = 388 bits (956), Expect = e-107
Identities = 203/537 (37%), Positives = 286/537 (53%), Gaps = 47/537 (8%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN 115
+PCSRTCGGGV+ ++R C +G C G + SC T+ CP+ + DFRAEQCA+++
Sbjct: 36 SPCSRTCGGGVSFRERPCYSQRRDGGSSCVGPARSHRSCRTESCPDGARDFRAEQCAEFD 95
Query: 116 NVTFRGKKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQ 175
F+G++YRW+PY CEL C+ G+ FYY+H+E V+DGT C DVCVDG C+
Sbjct: 96 GAEFQGRRYRWLPYYSAPNKCELNCIPKGENFYYKHREAVVDGTPCEPGKRDVCVDGSCR 155
Query: 176 PVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITE 235
VGCD L S+ +EDKC +C G+G C+ + DL +GYN IL++P GAT+I I E
Sbjct: 156 VVGCDHELDSSKQEDKCLRCGGDGTTCYPVAGTFDANDLSRGYNQILIVPMGATSILIDE 215
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPIN 295
S N+LA+++ G YYLNG + I+ R++ A + +YER +G AP++L + GP +
Sbjct: 216 AAASRNFLAVKNVRGEYYLNGHWTIEAARALPAASTILHYERGAEGDLAPERLHARGPTS 275
Query: 296 EPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCR 355
EPL + L+ + N GV YEY LP+ + P+ +SW HG++S CSA CGGG QSR V C
Sbjct: 276 EPLVIELISQEPNPGVHYEYHLPLRR---PSPGFSWSHGSWSDCSAECGGGHQSRLVFCT 332
Query: 356 SREELEVVDEGLCDDGLKPATNQTCNTQACPP------------------------QWVP 391
+ E + +C +PA ++CN CP W
Sbjct: 333 I--DHEAYPDHMCQRQPRPADRRSCNLHPCPETKRTSYLHRPGAWRLAGAQRVCGNSWKA 390
Query: 392 GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP 451
G W+ CS CG G++SR V C G+ V++ EC L G PA+ ++CN+ C
Sbjct: 391 GPWAPCSASCG-GGSQSRSVYCISSDGAGIQEAVEEAECAGLPGKPPAI-QACNLQ-RCA 447
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPCELEPCEG 510
W PW C CG G + R V C R ++L CS E++P +PC E C
Sbjct: 448 AWSPEPWGECSVSCGVGVRKRSVTC---RGERGSLLHTAACSLEDRPPLTEPCVHEDCPL 504
Query: 511 VD---WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCS--YHPTPALEEPCD 561
+ W V W C +C + R R C + S C H P EPC+
Sbjct: 505 LSDQAWHVGTWGLCSKSCSSGTRRRQVICA-----IGPPSHCGSLQHSKPVDVEPCN 556
Score = 101 bits (243), Expect = 2e-20
Identities = 71/189 (37%), Positives = 85/189 (44%), Gaps = 25/189 (13%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREEL---EVVDEGLCDDGL--KPATNQTCNTQA 384
SW G ++ CSA+CGGG QSR V C S + E V+E C GL KP Q CN Q
Sbjct: 387 SWKAGPWAPCSASCGGGSQSRSVYCISSDGAGIQEAVEEAECA-GLPGKPPAIQACNLQR 445
Query: 385 CPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC 444
C W P W CS CG G R R V C G S++ C L +P L E C
Sbjct: 446 CAA-WSPEPWGECSVSCGV-GVRKRSVTCRG--ERG--SLLHTAACS--LEDRPPLTEPC 497
Query: 445 NVDAACP-----TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLD 499
V CP W + W C K C SG + RQV+C L KP+D
Sbjct: 498 -VHEDCPLLSDQAWHVGTWGLCSKSCSSGTRRRQVICAIGPPSHCGSL-----QHSKPVD 551
Query: 500 RQPCELEPC 508
+PC +PC
Sbjct: 552 VEPCNTQPC 560
Score = 94.7 bits (225), Expect = 3e-18
Identities = 72/267 (26%), Positives = 102/267 (38%), Gaps = 47/267 (17%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCE- 509
+W W C CG G Q+R V C + D C + +P DR+ C L PC
Sbjct: 307 SWSHGSWSDCSAECGGGHQSRLVFCTIDHEA----YPDHMCQRQPRPADRRSCNLHPCPE 362
Query: 510 ----------------------GVDWMVSEWTGCD-TCLATVRSRVAQCVTKD----YRV 542
G W W C +C +SR C++ D
Sbjct: 363 TKRTSYLHRPGAWRLAGAQRVCGNSWKAGPWAPCSASCGGGSQSRSVYCISSDGAGIQEA 422
Query: 543 VNSSFCSYHP-TPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGA 601
V + C+ P P + C+ + A W W +CSV CGVG + R V C + +
Sbjct: 423 VEEAECAGLPGKPPAIQACNLQRCAA----WSPEPWGECSVSCGVGVRKRSVTC-RGERG 477
Query: 602 SVMKVDDSNCPKEEKYNDSKPCEVPEEKCP----SKWYAAPWSECTKSCGKGLRFRSVVC 657
S++ + C E++ ++PC E CP W+ W C+KSC G R R V+C
Sbjct: 478 SLLHT--AACSLEDRPPLTEPCV--HEDCPLLSDQAWHVGTWGLCSKSCSSGTRRRQVIC 533
Query: 658 LRGGKEFSDCPKKSLPDSAGSCNEQSC 684
G + S P CN Q C
Sbjct: 534 AIGPPSHCGSLQHSKPVDVEPCNTQPC 560
Score = 83.4 bits (197), Expect = 8e-15
Identities = 36/87 (41%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 1492 DCSTSKYGCCPDGQTLAEGPKFFGCTDIPENKQ-VACSLAKDRGSGRDYSVYWYYDMEYG 1550
+C S++GCC D A GP GC P + V C L GS D++ WY+ G
Sbjct: 656 ECRGSQFGCCYDNVATAAGPLGEGCVGQPSHAYPVRCLLPSAHGSCADWAARWYFVASVG 715
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVC 1577
C+RFWYGG GN N FA+++EC C
Sbjct: 716 QCNRFWYGGCHGNANNFASEQECMSSC 742
Score = 79.8 bits (188), Expect = 1e-13
Identities = 58/210 (27%), Positives = 83/210 (39%), Gaps = 31/210 (14%)
Query: 507 PCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
P G W W+ C C +SR+ C T D+ C P PA C+
Sbjct: 302 PSPGFSWSHGSWSDCSAECGGGHQSRLVFC-TIDHEAYPDHMCQRQPRPADRRSCNLHPC 360
Query: 566 P---------------------ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVM 604
P C W A W+ CS CG G ++R V+C DGA +
Sbjct: 361 PETKRTSYLHRPGAWRLAGAQRVCGNSWKAGPWAPCSASCGGGSQSRSVYCISSDGAGIQ 420
Query: 605 K-VDDSNCP-KEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL--RG 660
+ V+++ C K + C + ++C + W PW EC+ SCG G+R RSV C RG
Sbjct: 421 EAVEEAECAGLPGKPPAIQACNL--QRC-AAWSPEPWGECSVSCGVGVRKRSVTCRGERG 477
Query: 661 G-KEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+ C + P C + C L +
Sbjct: 478 SLLHTAACSLEDRPPLTEPCVHEDCPLLSD 507
Score = 64.9 bits (151), Expect = 3e-09
Identities = 24/52 (46%), Positives = 33/52 (63%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
C LP G+C + RWY+ + QC++F YGGC GNANNF + + C S C+
Sbjct: 692 CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQ 743
Score = 64.5 bits (150), Expect = 4e-09
Identities = 25/59 (42%), Positives = 35/59 (59%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
P P C LP+ G CA++ +W++ S +C +F+YGGC GN N F S+ EC S C
Sbjct: 684 PSHAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 742
Score = 61.7 bits (143), Expect = 3e-08
Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 1866 CAPFQYGGCGGNTNNFASE--EHCQYYCHFTQDV-CQLPMLAGPCNDSIVSWFYDASRDA 1922
C Q+G C N A E C V C LP G C D W++ AS
Sbjct: 657 CRGSQFGCCYDNVATAAGPLGEGCVGQPSHAYPVRCLLPSAHGSCADWAARWYFVASVGQ 716
Query: 1923 CSQFAYGGCGGNDNRFASRDECESRCR 1949
C++F YGGC GN N FAS EC S C+
Sbjct: 717 CNRFWYGGCHGNANNFASEQECMSSCQ 743
Score = 60.9 bits (141), Expect = 5e-08
Identities = 40/115 (34%), Positives = 48/115 (41%), Gaps = 6/115 (5%)
Query: 1606 SEREQCSQFVYGGCLGNANNF--DTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGF 1663
+E +C +G C N E C Q A +C LP GSCA RW F
Sbjct: 652 NEPSECRGSQFGCCYDNVATAAGPLGEGCVGQPSHAYPV-RCLLPSAHGSCADWAARWYF 710
Query: 1664 NDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQ-PRCSQPREQGGCNET 1717
+C F +GGC GN+N F SE C C G+L PR QP G T
Sbjct: 711 VASVGQCNRFWYGGCHGNANNFASEQECMSSCQ--GSLHGPRRPQPGASGRSTHT 763
Score = 60.5 bits (140), Expect = 6e-08
Identities = 24/52 (46%), Positives = 29/52 (55%)
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
RC P G C + AA W+F + G+C F+Y GC GN N F E C SSC
Sbjct: 691 RCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 742
Score = 58.4 bits (135), Expect = 3e-07
Identities = 25/60 (41%), Positives = 30/60 (50%)
Query: 1832 QPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
QP C + G C + RW + A G+C F YGGC GN NNFASE+ C C
Sbjct: 683 QPSHAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 742
Score = 50.4 bits (115), Expect = 7e-05
Identities = 20/52 (38%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
CL P G C + ++YF C F YGGCHG N F++ EC C+
Sbjct: 692 CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQ 743
Score = 40.3 bits (90), Expect = 0.073
Identities = 17/39 (43%), Positives = 21/39 (53%)
Query: 1329 HTPAEDAEMKGCPLTCATSRFGCCPDDVTPAHGPDGEGC 1367
H + + P C S+FGCC D+V A GP GEGC
Sbjct: 642 HNTHQPQAQQNEPSECRGSQFGCCYDNVATAAGPLGEGC 680
Score = 35.9 bits (79), Expect = 1.6
Identities = 24/58 (41%), Positives = 27/58 (46%), Gaps = 7/58 (12%)
Query: 1190 PEEKGCPPSLCAESLFGCCLSDNKTAAGGNDQEGCPPMP----PACKLAP--YGCCAD 1241
P+ + PS C S FGCC DN A G EGC P P L P +G CAD
Sbjct: 647 PQAQQNEPSECRGSQFGCCY-DNVATAAGPLGEGCVGQPSHAYPVRCLLPSAHGSCAD 703
Score = 35.5 bits (78), Expect = 2.1
Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 7/52 (13%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACP 386
+S CS TCGGG+ R+ C S+ D G G PA ++++C T++CP
Sbjct: 35 WSPCSRTCGGGVSFRERPCYSQRR----DGGSSCVG--PARSHRSCRTESCP 80
Score = 35.1 bits (77), Expect = 2.7
Identities = 12/24 (50%), Positives = 17/24 (70%)
Query: 1172 CKETRFGCCSDGVSAALGPEEKGC 1195
C+ ++FGCC D V+ A GP +GC
Sbjct: 657 CRGSQFGCCYDNVATAAGPLGEGC 680
Score = 34.7 bits (76), Expect = 3.6
Identities = 12/25 (48%), Positives = 16/25 (64%)
Query: 1142 KCATTKFGCCPDKRTAASGPFDEGC 1166
+C ++FGCC D A+GP EGC
Sbjct: 656 ECRGSQFGCCYDNVATAAGPLGEGC 680
>AY692424-1|AAW47397.1| 1117|Homo sapiens ADAMTS6 variant 2 protein.
Length = 1117
Score = 385 bits (948), Expect = e-106
Identities = 195/511 (38%), Positives = 275/511 (53%), Gaps = 18/511 (3%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQ-CTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV+S R C P+G + C G +Y SC T CP S DFR +QCA ++N
Sbjct: 570 CSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDN 629
Query: 117 VTFRGKKYRWVPYLKVS-KPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQ 175
+ FRGK Y W PY KPC L C+ G FY VIDGT+CN DS D+C++G C+
Sbjct: 630 MPFRGKYYNWKPYTGGGVKPCALNCLAEGYNFYTERAPAVIDGTQCNADSLDICINGECK 689
Query: 176 PVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITE 235
VGCD +LGS+A+ED+CR C G+G C + N R GY +++ IP G+ I + E
Sbjct: 690 HVGCDNILGSDAREDRCRVCGGDGSTCDAIEGFFNDSLPRGGYMEVVQIPRGSVHIEVRE 749
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPIN 295
+ S NY+AL+S+ YY+NG + ID+PR +AG ++Y+R P+ L +LGP +
Sbjct: 750 VAMSKNYIALKSEGDDYYINGAWTIDWPRKFDVAGTAFHYKRPTD---EPESLEALGPTS 806
Query: 296 EPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQR--YSWVHGNFSSCSATCGGGIQSRDVT 353
E L + +LL ++N+G+ Y++++PI + ++W H +S CSATC GG+Q ++V
Sbjct: 807 ENLIVMVLLQEQNLGIRYKFNVPITRTGSGDNEVGFTWNHQPWSECSATCAGGVQRQEVV 866
Query: 354 CRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR 412
C+ ++ +V CD KP NQ CNT+ CPP+W G+W CSK C G R+R V
Sbjct: 867 CKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTC-DGGMRTRAVL 925
Query: 413 CEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTR 472
C + I +D C L +P E CN + P W W C CG G + R
Sbjct: 926 CIRKIGPSEEETLDYSGC---LTHRPVEKEPCNNQSCPPQWVALDWSECTPKCGPGFKHR 982
Query: 473 QVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEGVDWMVSEWTGCDT-CLATVRS 530
V+C K++ +C EE KP R C L C W+ +W C C +
Sbjct: 983 IVLC--KSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQM 1040
Query: 531 RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
R QC++ Y SS C P + C+
Sbjct: 1041 RTVQCLS--YTGQASSDCLETVRPPSMQQCE 1069
Score = 131 bits (316), Expect = 3e-29
Identities = 76/244 (31%), Positives = 117/244 (47%), Gaps = 21/244 (8%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQ-PCELEPCE 509
TW PW C C G Q ++VVC + ++ +++ ++ C + KP + Q C EPC
Sbjct: 843 TWNHQPWSECSATCAGGVQRQEVVCKRLDDN--SIVQNNYCDPDSKPPENQRACNTEPCP 900
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDK 564
+W + +W C TC +R+R C+ K + ++ S C H P +EPC+
Sbjct: 901 P-EWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTH-RPVEKEPCNNQ- 957
Query: 565 LPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCE 624
+C QW A WS+C+ +CG G K R V C D + + CP+E K C
Sbjct: 958 --SCPPQWVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPA--AQCPEESKPPVRIRCS 1013
Query: 625 VPEEKCPS-KWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQ 682
+ +CP +W W +C+ CG G + R+V CL G+ SDC + P S C E
Sbjct: 1014 LG--RCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASSDCLETVRPPSMQQC-ES 1070
Query: 683 SCEA 686
C++
Sbjct: 1071 KCDS 1074
Score = 114 bits (274), Expect = 4e-24
Identities = 75/277 (27%), Positives = 118/277 (42%), Gaps = 17/277 (6%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W WS CS C G + +EV C+++ N S+V + C D P +CN +
Sbjct: 844 WNHQPWSECSATCA-GGVQRQEVVCKRLDDN---SIVQNNYC-DPDSKPPENQRACNTEP 898
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQK-NNGRINVLSDDECSEEKPLDRQPCELEP 507
P WFI W C K C G +TR V+C +K L C +P++++PC +
Sbjct: 899 CPPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQS 958
Query: 508 CEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDY-RVVNSSFCSYHPTPALEEPCDKDKL 565
C W+ +W+ C C + R+ C + D + ++ C P + C +
Sbjct: 959 CPP-QWVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRC 1017
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGAS----VMKVDDSNCPKEEKYNDSK 621
P +W W +CS +CG+G++ R V C + G + + V + + E DS
Sbjct: 1018 PP--PRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASSDCLETVRPPSMQQCESKCDST 1075
Query: 622 PCEVPEE-KCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
P EE K +K P K C + FR + C
Sbjct: 1076 PISNTEECKDVNKVAYCPLVLKFKFCSRAY-FRQMCC 1111
Score = 88.2 bits (209), Expect = 3e-16
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 14/183 (7%)
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVT-KDYRVVNSSFCSYHPTPALEE-PCDKDKLP 566
G W W+ C TC V+ + C D +V +++C P + C+ +
Sbjct: 841 GFTWNHQPWSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEP-- 898
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMK-VDDSNCPKEEKYNDSKPCEV 625
C +W+ W +CS C G +TR V C + G S + +D S C + +PC
Sbjct: 899 -CPPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPV-EKEPCN- 955
Query: 626 PEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG--GKEF--SDCPKKSLPDSAGSCNE 681
+ CP +W A WSECT CG G + R V+C K F + CP++S P C+
Sbjct: 956 -NQSCPPQWVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSL 1014
Query: 682 QSC 684
C
Sbjct: 1015 GRC 1017
Score = 72.9 bits (171), Expect = 1e-11
Identities = 45/146 (30%), Positives = 67/146 (45%), Gaps = 19/146 (13%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNC-PKEEKYNDSKPCEVPEEKC 630
W WS+CS C G + + V C + D S+ V ++ C P + + + C E C
Sbjct: 844 WNHQPWSECSATCAGGVQRQEVVCKRLDDNSI--VQNNYCDPDSKPPENQRACNT--EPC 899
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVCLR--GGKE-----FSDCPKKSLPDSAGSCNEQS 683
P +W+ W EC+K+C G+R R+V+C+R G E +S C P CN QS
Sbjct: 900 PPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGC-LTHRPVEKEPCNNQS 958
Query: 684 CEALGEGSGYFTSLDLESTFPEIGSG 709
C + +LD P+ G G
Sbjct: 959 CPP------QWVALDWSECTPKCGPG 978
>AB095949-1|BAC23125.1| 1021|Homo sapiens KIAA2029 protein protein.
Length = 1021
Score = 372 bits (916), Expect = e-102
Identities = 208/568 (36%), Positives = 293/568 (51%), Gaps = 38/568 (6%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSRTCGGGV+ + R+C P+ G C G C +Q CP +S+DFRA QCA++
Sbjct: 393 SPCSRTCGGGVSHRSRLCTNPKPSHGGKFCEGSTRTLKLCNSQKCPRDSVDFRAAQCAEH 452
Query: 115 NNVTFRGKKYRWVPYLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDG 172
N+ FRG+ Y+W PY +V C+L C+ G F++ KV DGT C++DS +VC+DG
Sbjct: 453 NSRRFRGRHYKWKPYTQVEDQDLCKLYCIAEGFDFFFSLSNKVKDGTPCSEDSRNVCIDG 512
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIY 232
+C+ VGCD +LGS+A ED C C GN C + L Y ++ IP GA +I
Sbjct: 513 ICERVGCDNVLGSDAVEDVCGVCNGNNSACTIHRGLYTKHHHTNQYYHMVTIPSGARSIR 572
Query: 233 ITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLG 292
I E+ S +Y+++R+ YYLNG + +D+P +G ++Y R+ P+ L + G
Sbjct: 573 IYEMNVSTSYISVRNALRRYYLNGHWTVDWPGRYKFSGTTFDYRRS---YNEPENLIATG 629
Query: 293 PINEPLYLSLLLIDENVGVEYEYSLP---IEKAPLPTQRYSWVHGNFSSCSATCGGGIQS 349
P NE L + LL N GV +EYS+P EK P Y+W S CS +CGGG +
Sbjct: 630 PTNETLIVELLFQGRNPGVAWEYSMPRLGTEKQPPAQPSYTWAIVR-SECSVSCGGGQMT 688
Query: 350 RDVTCRSREELEVVDEGLCDDGLKPATNQT-CNTQACPPQWVPGNWSRCSKRCGKDGTRS 408
C R+ V+ C+ +P T C ACPP W GNWS CS+ CG G +S
Sbjct: 689 VREGC-YRDLKFQVNMSFCNPKTRPVTGLVPCKVSACPPSWSVGNWSACSRTCG-GGAQS 746
Query: 409 REVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSG 468
R V+C + + V C P P+ ++CN + P W PW C CG G
Sbjct: 747 RPVQCTRRVHYD-SEPVPASLCPQ---PAPSSRQACNSQSCPPAWSAGPWAECSHTCGKG 802
Query: 469 QQTRQVVCYQKN-NGRINVLSDDEC-SEEKPLDRQPCELEPC---EGVDWMVSEWTGCD- 522
+ R V C N + R +L D C SE KP + C L+ C + + W+VS W+ C
Sbjct: 803 WRKRAVACKSTNPSARAQLLPDAVCTSEPKPRMHEACLLQRCHKPKKLQWLVSAWSQCSV 862
Query: 523 TCLATVRSRVAQCVTK----DYRVVNSSFCSYHPTPALE-------EPCDKDKLPAC--- 568
TC + R +C K YR + S CS+ P P+LE PC + A
Sbjct: 863 TCERGTQKRFLKCAEKYVSGKYRELASKKCSHLPKPSLELERACAPLPCPRHPPFAAAGP 922
Query: 569 -QVQWYATQWSKCSVECGVGKKTRRVFC 595
+ W+A+ WS+C+ CG G +TR V C
Sbjct: 923 SRGSWFASPWSQCTASCGGGVQTRSVQC 950
Score = 133 bits (321), Expect = 7e-30
Identities = 93/326 (28%), Positives = 134/326 (41%), Gaps = 30/326 (9%)
Query: 382 TQACPPQWVPGNW----SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
T+ PP W S CS CG RE C + L V+ C P
Sbjct: 659 TEKQPPAQPSYTWAIVRSECSVSCGGGQMTVRE-GCYR----DLKFQVNMSFCNPKTRPV 713
Query: 438 PALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKP 497
L C V A P+W + W C + CG G Q+R V C ++ + + C + P
Sbjct: 714 TGLVP-CKVSACPPSWSVGNWSACSRTCGGGAQSRPVQCTRRVHYDSEPVPASLCPQPAP 772
Query: 498 LDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKD----YRVVNSSFCSYHP 552
RQ C + C W W C TC R R C + + +++ + C+ P
Sbjct: 773 SSRQACNSQSCPPA-WSAGPWAECSHTCGKGWRKRAVACKSTNPSARAQLLPDAVCTSEP 831
Query: 553 TPALEEPCDKDKL-PACQVQWYATQWSKCSVECGVGKKTRRVFCG-KFDGASVMKVDDSN 610
P + E C + ++QW + WS+CSV C G + R + C K+ ++
Sbjct: 832 KPRMHEACLLQRCHKPKKLQWLVSAWSQCSVTCERGTQKRFLKCAEKYVSGKYRELASKK 891
Query: 611 C-----PKEEKYNDSKPCEVPEEKC-----PSK--WYAAPWSECTKSCGKGLRFRSVVCL 658
C P E P P PS+ W+A+PWS+CT SCG G++ RSV CL
Sbjct: 892 CSHLPKPSLELERACAPLPCPRHPPFAAAGPSRGSWFASPWSQCTASCGGGVQTRSVQCL 951
Query: 659 RGGKEFSDCPKKSLPDSAGSCNEQSC 684
GG+ S C P ++ +CN C
Sbjct: 952 AGGRPASGCLLHQKPSASLACNTHFC 977
Score = 66.5 bits (155), Expect = 1e-09
Identities = 52/164 (31%), Positives = 74/164 (45%), Gaps = 17/164 (10%)
Query: 532 VAQCVTKDYRVVNSSFCSYHPTPALEEPCDK---DKLPACQVQW-YATQWSKCSVECGVG 587
+A T + +V F +P A E + +K P Q + +A S+CSV CG G
Sbjct: 626 IATGPTNETLIVELLFQGRNPGVAWEYSMPRLGTEKQPPAQPSYTWAIVRSECSVSCGGG 685
Query: 588 KKTRRVFCGKFDGASVMKVDDSNC-PKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSC 646
+ T R C + +V+ S C PK PC+V CP W WS C+++C
Sbjct: 686 QMTVREGCYR---DLKFQVNMSFCNPKTRPVTGLVPCKV--SACPPSWSVGNWSACSRTC 740
Query: 647 GKGLRFRSVVCLRGGKEFSD------CPKKSLPDSAGSCNEQSC 684
G G + R V C R S+ CP+ + P S +CN QSC
Sbjct: 741 GGGAQSRPVQCTRRVHYDSEPVPASLCPQPA-PSSRQACNSQSC 783
Score = 44.4 bits (100), Expect = 0.004
Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 328 RYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP 386
R SW +S C+A+CGGG+Q+R V C + C KP+ + CNT CP
Sbjct: 924 RGSWFASPWSQCTASCGGGVQTRSVQCLAGGR----PASGCLLHQKPSASLACNTHFCP 978
Score = 39.9 bits (89), Expect = 0.096
Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 320 EKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQT 379
++ P PT + ++S CS TCGGG+ R C + + C+ + T +
Sbjct: 376 DEGPKPTHGHWSDWSSWSPCSRTCGGGVSHRSRLCTNPKPSH--GGKFCEGSTR--TLKL 431
Query: 380 CNTQACPPQWVPGNWSRCSK 399
CN+Q CP V ++C++
Sbjct: 432 CNSQKCPRDSVDFRAAQCAE 451
>AB209685-1|BAD92922.1| 530|Homo sapiens a disintegrin and
metalloprotease with thrombospondin motifs-6 variant
protein.
Length = 530
Score = 361 bits (889), Expect = 1e-98
Identities = 182/488 (37%), Positives = 259/488 (53%), Gaps = 17/488 (3%)
Query: 80 GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNVTFRGKKYRWVPYLKVS-KPCEL 138
G C G +Y SC T CP S DFR +QCA ++N+ FRGK Y W PY KPC L
Sbjct: 6 GGKYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDNMPFRGKYYNWKPYTGGGVKPCAL 65
Query: 139 TCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGN 198
C+ G FY VIDGT+CN DS D+C++G C+ VGCD +LGS+A+ED+CR C G+
Sbjct: 66 NCLAEGYNFYTERAPAVIDGTQCNADSLDICINGECKHVGCDNILGSDAREDRCRVCGGD 125
Query: 199 GHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDY 258
G C + N R GY +++ IP G+ I + E+ S NY+AL+S+ YY+NG +
Sbjct: 126 GSTCDAIEGFFNDSLPRGGYMEVVQIPRGSVHIEVREVAMSKNYIALKSEGDDYYINGAW 185
Query: 259 HIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLP 318
ID+PR +AG ++Y+R P+ L +LGP +E L + +LL ++N+G+ Y++++P
Sbjct: 186 TIDWPRKFDVAGTAFHYKRPTD---EPESLEALGPTSENLIVMVLLQEQNLGIRYKFNVP 242
Query: 319 IEKAPLPTQR--YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPAT 376
I + ++W H +S CSATC GG+Q ++V C+ ++ +V CD KP
Sbjct: 243 ITRTGSGDNEVGFTWNHQPWSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPE 302
Query: 377 NQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLG 435
NQ CNT+ CPP+W G+W CSK C G R+R V C + I +D C L
Sbjct: 303 NQRACNTEPCPPEWFIGDWLECSKTC-DGGMRTRAVLCIRKIGPSEEETLDYSGC---LT 358
Query: 436 PKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE 495
+P E CN + P W W C CG G + R V+C K++ +C EE
Sbjct: 359 HRPVEKEPCNNQSCPPQWVALDWSECTPKCGPGFKHRIVLC--KSSDLSKTFPAAQCPEE 416
Query: 496 -KPLDRQPCELEPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFCSYHPT 553
KP R C L C W+ +W C C + R QC++ Y SS C
Sbjct: 417 SKPPVRIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLS--YTGQASSDCLETVR 474
Query: 554 PALEEPCD 561
P + C+
Sbjct: 475 PPSMQQCE 482
Score = 131 bits (316), Expect = 3e-29
Identities = 76/244 (31%), Positives = 117/244 (47%), Gaps = 21/244 (8%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQ-PCELEPCE 509
TW PW C C G Q ++VVC + ++ +++ ++ C + KP + Q C EPC
Sbjct: 256 TWNHQPWSECSATCAGGVQRQEVVCKRLDDN--SIVQNNYCDPDSKPPENQRACNTEPCP 313
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDK 564
+W + +W C TC +R+R C+ K + ++ S C H P +EPC+
Sbjct: 314 P-EWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTH-RPVEKEPCNNQ- 370
Query: 565 LPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCE 624
+C QW A WS+C+ +CG G K R V C D + + CP+E K C
Sbjct: 371 --SCPPQWVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPA--AQCPEESKPPVRIRCS 426
Query: 625 VPEEKCPS-KWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQ 682
+ +CP +W W +C+ CG G + R+V CL G+ SDC + P S C E
Sbjct: 427 LG--RCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASSDCLETVRPPSMQQC-ES 483
Query: 683 SCEA 686
C++
Sbjct: 484 KCDS 487
Score = 114 bits (274), Expect = 4e-24
Identities = 75/277 (27%), Positives = 118/277 (42%), Gaps = 17/277 (6%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W WS CS C G + +EV C+++ N S+V + C D P +CN +
Sbjct: 257 WNHQPWSECSATCA-GGVQRQEVVCKRLDDN---SIVQNNYC-DPDSKPPENQRACNTEP 311
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQK-NNGRINVLSDDECSEEKPLDRQPCELEP 507
P WFI W C K C G +TR V+C +K L C +P++++PC +
Sbjct: 312 CPPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQS 371
Query: 508 CEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDY-RVVNSSFCSYHPTPALEEPCDKDKL 565
C W+ +W+ C C + R+ C + D + ++ C P + C +
Sbjct: 372 CPP-QWVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRC 430
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGAS----VMKVDDSNCPKEEKYNDSK 621
P +W W +CS +CG+G++ R V C + G + + V + + E DS
Sbjct: 431 PP--PRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASSDCLETVRPPSMQQCESKCDST 488
Query: 622 PCEVPEE-KCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
P EE K +K P K C + FR + C
Sbjct: 489 PISNTEECKDVNKVAYCPLVLKFKFCSRAY-FRQMCC 524
Score = 88.2 bits (209), Expect = 3e-16
Identities = 54/183 (29%), Positives = 81/183 (44%), Gaps = 14/183 (7%)
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVT-KDYRVVNSSFCSYHPTPALEE-PCDKDKLP 566
G W W+ C TC V+ + C D +V +++C P + C+ +
Sbjct: 254 GFTWNHQPWSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEP-- 311
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMK-VDDSNCPKEEKYNDSKPCEV 625
C +W+ W +CS C G +TR V C + G S + +D S C + +PC
Sbjct: 312 -CPPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPV-EKEPCN- 368
Query: 626 PEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG--GKEF--SDCPKKSLPDSAGSCNE 681
+ CP +W A WSECT CG G + R V+C K F + CP++S P C+
Sbjct: 369 -NQSCPPQWVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSL 427
Query: 682 QSC 684
C
Sbjct: 428 GRC 430
Score = 72.9 bits (171), Expect = 1e-11
Identities = 45/146 (30%), Positives = 67/146 (45%), Gaps = 19/146 (13%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNC-PKEEKYNDSKPCEVPEEKC 630
W WS+CS C G + + V C + D S+ V ++ C P + + + C E C
Sbjct: 257 WNHQPWSECSATCAGGVQRQEVVCKRLDDNSI--VQNNYCDPDSKPPENQRACNT--EPC 312
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVCLR--GGKE-----FSDCPKKSLPDSAGSCNEQS 683
P +W+ W EC+K+C G+R R+V+C+R G E +S C P CN QS
Sbjct: 313 PPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGC-LTHRPVEKEPCNNQS 371
Query: 684 CEALGEGSGYFTSLDLESTFPEIGSG 709
C + +LD P+ G G
Sbjct: 372 CPP------QWVALDWSECTPKCGPG 391
>BC063283-1|AAH63283.1| 1221|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 18 protein.
Length = 1221
Score = 359 bits (882), Expect = 8e-98
Identities = 222/633 (35%), Positives = 314/633 (49%), Gaps = 60/633 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV Q+R C P G C G Y C C ENSLDFRA+QCA+YN+
Sbjct: 601 CSRTCGGGVKFQERHCNNPKPQYGGIFCPGSSRIYQLCNINPCNENSLDFRAQQCAEYNS 660
Query: 117 VTFRGKKYRWVPYLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVC 174
FRG Y+W PY KV + C+L C F++ KV DGT C+ + DVC+DGVC
Sbjct: 661 KPFRGWFYQWKPYTKVEEEDRCKLYCKAENFEFFFAMSGKVKDGTPCSPNKNDVCIDGVC 720
Query: 175 QPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYIT 234
+ VGCD LGS A D C C+G+ C K L Q Y +++IP GA +I I
Sbjct: 721 ELVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLNQHKANEYYPVVIIPAGARSIEIQ 780
Query: 235 EIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPI 294
E++ S++YLA+RS + YYL G + ID+P AG + Y+R+ P++L + GP
Sbjct: 781 ELQVSSSYLAVRSLSQKYYLTGGWSIDWPGEFPFAGTTFEYQRS---FNRPERLYAPGPT 837
Query: 295 NEPLYLSLLLIDENVGVEYEYSLP--IEKAPLPTQR--YSWVHGNFSSCSATCGGGIQSR 350
NE L +L+ +N G+ ++Y+LP + P T+R Y+W S CS +CGGG +
Sbjct: 838 NETLVFEILMQGKNPGIAWKYALPKVMNGTPPATKRPAYTWSIVQ-SECSVSCGGGYINV 896
Query: 351 DVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSRCSKRCGKDGTRSR 409
C R++ V+ C KP T + CN +CP W+PG WS CSK C G +SR
Sbjct: 897 KAIC-LRDQNTQVNSSFCSAKTKPVTEPKICNAFSCPAYWMPGEWSTCSKACA-GGQQSR 954
Query: 410 EVRCEKIITNGLPSVVDDKECFDLLG-PKPALYESCNVDAACPTWFISPWKPCDKLCGSG 468
+++C P ++ L P ++CN A P W + PW C K CG G
Sbjct: 955 KIQC----VQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLGPWSQCSKTCGRG 1010
Query: 469 QQTRQVVCYQKNNGRINVLSDDEC-SEEKPLDRQPCELEPC---EGVDWMVSEWTGCD-T 523
+ R+++C L + +C S +P ++ C L C + W+ S W+ C T
Sbjct: 1011 VRKRELLC---KGSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRLQWVASSWSECSAT 1067
Query: 524 CLATVRSRVAQCVTKDYRVVNSSF----CS--YHPTPALEEPCDKDKLPACQVQ-----W 572
C VR R +C K ++ +F C P LEE C++ PA V W
Sbjct: 1068 CGLGVRKREMKCSEKGFQGKLITFPERRCRNIKKPNLDLEETCNRRACPAHPVYNMVAGW 1127
Query: 573 YATQWSKCSVECGVGKKTRRVFC---GKFDGA-------SVMKVDDSN-CPKEEKYNDSK 621
Y+ W +C+V CG G +TR V C G+ + V++ ++N CP EK D
Sbjct: 1128 YSLPWQQCTVTCGGGVQTRSVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPAPEKREDPS 1187
Query: 622 PCE-------VPEE-KCPSKWYAAPWSECTKSC 646
+ VP+ C K+Y +C KSC
Sbjct: 1188 CVDFFNWCHLVPQHGVCNHKFYG---KQCCKSC 1217
Score = 134 bits (325), Expect = 2e-30
Identities = 78/257 (30%), Positives = 112/257 (43%), Gaps = 17/257 (6%)
Query: 444 CNVDAACPT-WFISPWKPCDKLCGSGQQTRQVVCYQKNN-GRINVLSDDECSEEKPLDRQ 501
CN +CP W W C K C GQQ+R++ C QK + + C P Q
Sbjct: 926 CNA-FSCPAYWMPGEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQ 984
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C C W + W+ C TC VR R C + S C+ P P L+E C
Sbjct: 985 ACNSHACPP-QWSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGC 1043
Query: 561 DKDKLPA-CQVQWYATQWSKCSVECGVGKKTRRVFCGK--FDGASVMKVDDSNCPKEEKY 617
+ P ++QW A+ WS+CS CG+G + R + C + F G ++ + C +K
Sbjct: 1044 VLGRCPKNSRLQWVASSWSECSATCGLGVRKREMKCSEKGFQG-KLITFPERRCRNIKKP 1102
Query: 618 NDSKPCEVPEEKCPSK--------WYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPK 669
N CP+ WY+ PW +CT +CG G++ RSV C++ G+ S C
Sbjct: 1103 NLDLEETCNRRACPAHPVYNMVAGWYSLPWQQCTVTCGGGVQTRSVHCVQQGRPSSSCLL 1162
Query: 670 KSLPDSAGSCNEQSCEA 686
P +CN C A
Sbjct: 1163 HQKPPVLRACNTNFCPA 1179
>AJ315734-1|CAC86015.1| 1072|Homo sapiens metalloprotease disintegrin
16 with thrombospondin type I motif protein.
Length = 1072
Score = 334 bits (820), Expect = 3e-90
Identities = 178/476 (37%), Positives = 251/476 (52%), Gaps = 22/476 (4%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSRTCGGGV+ + R+C P+ G C G C +Q CP +S+DFRA QCA++
Sbjct: 596 SPCSRTCGGGVSHRSRLCTNPKPSHGGKFCEGSTRTLKLCNSQKCPRDSVDFRAAQCAEH 655
Query: 115 NNVTFRGKKYRWVPYLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDG 172
N+ FRG+ Y+W PY +V C+L C+ G F++ KV DGT C++DS +VC+DG
Sbjct: 656 NSRRFRGRHYKWKPYTQVEDQDLCKLYCIAEGFDFFFSLSNKVKDGTPCSEDSRNVCIDG 715
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIY 232
+C+ VGCD +LGS+A ED C C GN C + L Y ++ IP GA +I
Sbjct: 716 ICERVGCDNVLGSDAVEDVCGVCNGNNSACTIHRGLYTKHHHTNQYYHMVTIPSGARSIR 775
Query: 233 ITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLG 292
I E+ S +Y+++R+ YYLNG + +D+P +G ++Y R+ P+ L + G
Sbjct: 776 IYEMNVSTSYISVRNALRRYYLNGHWTVDWPGRYKFSGTTFDYRRS---YNEPENLIATG 832
Query: 293 PINEPLYLSLLLIDENVGVEYEYSLP---IEKAPLPTQRYSWVHGNFSSCSATCGGGIQS 349
P NE L + LL N GV +EYS+P EK P Y+W S CS +CGGG +
Sbjct: 833 PTNETLIVELLFQGRNPGVAWEYSMPRLGTEKQPPAQPSYTWAIVR-SECSVSCGGGQMT 891
Query: 350 RDVTCRSREELEVVDEGLCDDGLKPATNQT-CNTQACPPQWVPGNWSRCSKRCGKDGTRS 408
C R+ V+ C+ +P T C ACPP W GNWS CS+ CG G +S
Sbjct: 892 VREGC-YRDLKFQVNMSFCNPKTRPVTGLVPCKVSACPPSWSVGNWSACSRTCG-GGAQS 949
Query: 409 REVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSG 468
R V+C + + V C P P+ ++CN + P W PW C CG G
Sbjct: 950 RPVQCTRRVHYD-SEPVPASLCPQ---PAPSSRQACNSQSCPPAWSAGPWAECSHTCGKG 1005
Query: 469 QQTRQVVCYQKN-NGRINVLSDDEC-SEEKPLDRQPCELEPC---EGVDWMVSEWT 519
+ R V C N + R +L D C SE KP + C L+ C + + W+VS W+
Sbjct: 1006 WRKRAVACKSTNPSARAQLLPDAVCTSEPKPRMHEACLLQRCHKPKKLQWLVSAWS 1061
Score = 79.0 bits (186), Expect = 2e-13
Identities = 43/116 (37%), Positives = 56/116 (48%), Gaps = 7/116 (6%)
Query: 543 VNSSFCSYHPTPALE-EPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGA 601
VN SFC+ P PC K+ AC W WS CS CG G ++R V C +
Sbjct: 904 VNMSFCNPKTRPVTGLVPC---KVSACPPSWSVGNWSACSRTCGGGAQSRPVQCTRRVHY 960
Query: 602 SVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
V S CP+ + + C + CP W A PW+EC+ +CGKG R R+V C
Sbjct: 961 DSEPVPASLCPQPAP-SSRQACN--SQSCPPAWSAGPWAECSHTCGKGWRKRAVAC 1013
Score = 66.5 bits (155), Expect = 1e-09
Identities = 52/164 (31%), Positives = 74/164 (45%), Gaps = 17/164 (10%)
Query: 532 VAQCVTKDYRVVNSSFCSYHPTPALEEPCDK---DKLPACQVQW-YATQWSKCSVECGVG 587
+A T + +V F +P A E + +K P Q + +A S+CSV CG G
Sbjct: 829 IATGPTNETLIVELLFQGRNPGVAWEYSMPRLGTEKQPPAQPSYTWAIVRSECSVSCGGG 888
Query: 588 KKTRRVFCGKFDGASVMKVDDSNC-PKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSC 646
+ T R C + +V+ S C PK PC+V CP W WS C+++C
Sbjct: 889 QMTVREGCYR---DLKFQVNMSFCNPKTRPVTGLVPCKV--SACPPSWSVGNWSACSRTC 943
Query: 647 GKGLRFRSVVCLRGGKEFSD------CPKKSLPDSAGSCNEQSC 684
G G + R V C R S+ CP+ + P S +CN QSC
Sbjct: 944 GGGAQSRPVQCTRRVHYDSEPVPASLCPQPA-PSSRQACNSQSC 986
Score = 39.9 bits (89), Expect = 0.096
Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
Query: 320 EKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQT 379
++ P PT + ++S CS TCGGG+ R C + + C+ + T +
Sbjct: 579 DEGPKPTHGHWSDWSSWSPCSRTCGGGVSHRSRLCTNPKPSH--GGKFCEGSTR--TLKL 634
Query: 380 CNTQACPPQWVPGNWSRCSK 399
CN+Q CP V ++C++
Sbjct: 635 CNSQKCPRDSVDFRAAQCAE 654
>AF163762-1|AAG35563.1| 1077|Homo sapiens zinc metalloendopeptidase
protein.
Length = 1077
Score = 332 bits (815), Expect = 1e-89
Identities = 180/511 (35%), Positives = 252/511 (49%), Gaps = 18/511 (3%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV+S R C P G C G ++ SC T DCP S DFR QC+++++
Sbjct: 533 CSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDS 592
Query: 117 VTFRGKKYRWVPYLKVS-KPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQ 175
+ FRGK Y+W Y K C LT + G FY V+DGT C D+ D+CV G C+
Sbjct: 593 IPFRGKFYKWKTYRGGGVKACSLTSLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECK 652
Query: 176 PVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITE 235
VGCD +LGS+ +EDKCR C G+G C T + + + GY D++ IP+G+ I+I +
Sbjct: 653 HVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQD 712
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPIN 295
+ S ++LAL+ + L G P + +AG + +QG L +LGPIN
Sbjct: 713 LNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQL---RQGPDQVQSLEALGPIN 769
Query: 296 EPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCR 355
L + +L E + Y ++ PI + LP YSW + ++ CSA C GG Q + V CR
Sbjct: 770 ASLIVMVLARTELPALRYRFNAPIARDSLPP--YSWHYAPWTKCSAQCAGGSQVQAVECR 827
Query: 356 SREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCE 414
++ + V C K P + CNT+ CPP WV GNWS CS+ C G RSR V C+
Sbjct: 828 NQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDA-GVRSRSVVCQ 886
Query: 415 KIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQV 474
+ ++ +DD C P+P + E+C+ P W W C CG G + R V
Sbjct: 887 RRVSAAEEKALDDSACPQ---PRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVV 943
Query: 475 VCYQKNNGRINVLSDDECS-EEKPLDRQPCELEPCEGVDWMVSEWTGCDT-CLATVRSRV 532
+C K+ L CS KP C L C W+ EW C C R R
Sbjct: 944 LC--KSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCGVGQRQRS 1001
Query: 533 AQCVTKDYRVVNSSFCSYHP--TPALEEPCD 561
+C + + + + P T E CD
Sbjct: 1002 VRCTSHTGQASHECTEALRPPTTQQCEAKCD 1032
Score = 122 bits (293), Expect = 2e-26
Identities = 75/250 (30%), Positives = 113/250 (45%), Gaps = 21/250 (8%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQP--CELEPCE 509
+W +PW C C G Q + V C +N + ++ CS L ++ C EPC
Sbjct: 802 SWHYAPWTKCSAQCAGGSQVQAVEC--RNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCP 859
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDK 564
DW+V W+ C +C A VRSR C + + + ++ S C P P + E C
Sbjct: 860 P-DWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACP-QPRPPVLEACHG-- 915
Query: 565 LPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCE 624
P C +W A WS+C+ CG G + R V C D + + ++C K + C
Sbjct: 916 -PTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLP--PAHCSPAAKPPATMRCN 972
Query: 625 VPEEKCP-SKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNEQ 682
+ +CP ++W A W EC+ CG G R RSV C G+ +C + P + C E
Sbjct: 973 L--RRCPPARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQC-EA 1029
Query: 683 SCEALGEGSG 692
C++ G G
Sbjct: 1030 KCDSPTPGDG 1039
Score = 41.9 bits (94), Expect = 0.024
Identities = 23/63 (36%), Positives = 30/63 (47%), Gaps = 5/63 (7%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
WV G + CSA CG G + R V C S + E C + L+P T Q C + P
Sbjct: 981 WVAGEWGECSAQCGVGQRQRSVRCTSHTG-QASHE--CTEALRPPTTQQCEAKCDSP--T 1035
Query: 391 PGN 393
PG+
Sbjct: 1036 PGD 1038
Score = 35.5 bits (78), Expect = 2.1
Identities = 16/59 (27%), Positives = 26/59 (44%), Gaps = 5/59 (8%)
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCP-----KKSLPDSAGSCNEQSC 684
P W+ APW++C+ C G + ++V C + P LP +CN + C
Sbjct: 800 PYSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPC 858
>BC130578-1|AAI30579.1| 1935|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 9 protein.
Length = 1935
Score = 327 bits (804), Expect = 2e-88
Identities = 214/665 (32%), Positives = 315/665 (47%), Gaps = 63/665 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN- 115
CSRTCGGG+ + R C P NG C G K+ SC T+ C + DFR EQCA ++
Sbjct: 600 CSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDG 659
Query: 116 ---NVTFRGKKYRWVPY---LKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
N+ RWVP + + C+L C G+ YY+ +++VIDGT C D+ D+C
Sbjct: 660 KHFNINGLLPNVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDIC 719
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGAT 229
V G+C+ GCD +L S A+ DKC C G+ +C T NT + GYN ++ IP GAT
Sbjct: 720 VQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNT--VHYGYNTVVRIPAGAT 777
Query: 230 TIYITEIEPS-----NNYLALRSKNGTYYLNGDYHIDF-PRSMTIAGALWNYERNQQGIT 283
I + + S +NYLAL S G + LNG++ + R + I A+ Y ++ T
Sbjct: 778 NIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSE---T 834
Query: 284 APDKLRSLGPINEPLYLSLLLIDE--NVGVEYEYSLPIEKAPLPTQRYSW-VHGNFSSCS 340
A +++ S I + L L +L + + N V Y +++PIE P Q++ W HG + +CS
Sbjct: 835 AVERINSTDRIEQELLLQVLSVGKLYNPDVRYSFNIPIEDKP---QQFYWNSHGPWQACS 891
Query: 341 ATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACPPQWVPGNWSRCSK 399
C G + + V R ++L V D+ CD +P + C T C +W + S CS
Sbjct: 892 KPCQGERKRKLVCTRESDQLTVSDQ-RCDRLPQPGHITEPCGTD-CDLRWHVASRSECSA 949
Query: 400 RCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPW 458
+CG G R+ ++ C K +G VDD C PKP+ E C+ + W S W
Sbjct: 950 QCGL-GYRTLDIYCAKYSRLDGKTEKVDDGFCSS--HPKPSNREKCSGECNTGGWRYSAW 1006
Query: 459 KPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEW 518
C K C G Q R+ +C N R +VL D +C+ ++ + Q C PC W +W
Sbjct: 1007 TECSKSCDGGTQRRRAICV---NTRNDVLDDSKCTHQEKVTIQRCSEFPCP--QWKSGDW 1061
Query: 519 TGC-DTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
+ C TC + R C + R +N C P + C + P C W A W
Sbjct: 1062 SECLVTCGKGHKHRQVWCQFGEDR-LNDRMCDPETKPTSMQTCQQ---PEC-ASWQAGPW 1116
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP------ 631
+CSV CG G + R V C G + VDD++C + D++ CE+P P
Sbjct: 1117 GQCSVTCGQGYQLRAVKC--IIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPET 1174
Query: 632 ---------SKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD---CPKKSLPDSAGSC 679
++W W+ C+ +CGKG R R V C +D C P + C
Sbjct: 1175 RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLPRPVAKEEC 1234
Query: 680 NEQSC 684
+ C
Sbjct: 1235 SVTPC 1239
Score = 173 bits (422), Expect = 4e-42
Identities = 118/376 (31%), Positives = 159/376 (42%), Gaps = 30/376 (7%)
Query: 320 EKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQT 379
E P P W +GN+ C+ CGGGI++R V C+ R E + C+ KP +
Sbjct: 1379 ESGPCP----QWAYGNWGECTKLCGGGIRTRLVVCQ-RSNGERFPDLSCEILDKPPDREQ 1433
Query: 380 CNTQACPPQ--WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CNT ACP W G WS CS CG+ G + R V C + +G S ++ C L K
Sbjct: 1434 CNTHACPHDAAWSTGPWSSCSVSCGR-GHKQRNVYC--MAKDG--SHLESDYCKHLA--K 1486
Query: 438 PALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EK 496
P + C CP W W C CG G Q R V C G + + EC+ +
Sbjct: 1487 PHGHRKCR-GGRCPKWKAGAWSQCSVSCGRGVQQRHVGC---QIGTHKIARETECNPYTR 1542
Query: 497 PLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPA 555
P + C+ C W EW C TC R R CV + V+ + C P
Sbjct: 1543 PESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARCDVSKRPV 1602
Query: 556 LEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGK-FDGASVMKVD---DSNC 611
E C L C+ W +WS+CSV CG G K R V C + + G + NC
Sbjct: 1603 DRESCS---LQPCEYVWITGEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINC 1659
Query: 612 PKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD-CPKK 670
P + PC + + + W W C+ SCG G+ RSV CL + S C
Sbjct: 1660 PGTQP-PSVHPCYLRDCPVSATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQPSHLCHTD 1718
Query: 671 SLPDSAGSC-NEQSCE 685
P+ +C N +CE
Sbjct: 1719 LKPEERKTCRNVYNCE 1734
Score = 169 bits (411), Expect = 9e-41
Identities = 107/340 (31%), Positives = 152/340 (44%), Gaps = 31/340 (9%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W G + +CS+TC GG Q R V C+ D C + +KP + C + C PQW
Sbjct: 1332 WRTGPWGACSSTCAGGSQRRVVVCQDENGYTAND---CVERIKPDEQRACESGPC-PQWA 1387
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
GNW C+K CG G R+R V C++ +NG D C ++L KP E CN AC
Sbjct: 1388 YGNWGECTKLCG-GGIRTRLVVCQR--SNG--ERFPDLSC-EIL-DKPPDREQCNTH-AC 1439
Query: 451 P---TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELE 506
P W PW C CG G + R V C K+ L D C KP + C
Sbjct: 1440 PHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSH---LESDYCKHLAKPHGHRKCRGG 1496
Query: 507 PCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
C W W+ C +C V+ R C +++ + C+ + P E C +
Sbjct: 1497 RCP--KWKAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRC 1554
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
P W A +W +C+ CG G + R+V C D + +V + C ++ D + C +
Sbjct: 1555 PL--YTWRAEEWQECTKTCGEGSRYRKVVCVD-DNKN--EVHGARCDVSKRPVDRESCSL 1609
Query: 626 PEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC--LRGGKE 663
+ C W WSEC+ +CGKG + R V C + GKE
Sbjct: 1610 --QPCEYVWITGEWSECSVTCGKGYKQRLVSCSEIYTGKE 1647
Score = 156 bits (379), Expect = 7e-37
Identities = 117/394 (29%), Positives = 165/394 (41%), Gaps = 61/394 (15%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLC---------------------- 368
W ++SSCS TCG G +R V C + + V+D C
Sbjct: 1242 WKALDWSSCSVTCGQGRATRQVMCVNYSD-HVIDRSECDQDYIPETDQDCSMSPCPQRTP 1300
Query: 369 DDGLK--PATNQTCNTQACPP---------QWVPGNWSRCSKRCGKDGTRSREVRCEKII 417
D GL P N+ ++ P QW G W CS C G++ R V C+
Sbjct: 1301 DSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCA-GGSQRRVVVCQD-- 1357
Query: 418 TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCY 477
NG + +C + + KP +C CP W W C KLCG G +TR VVC
Sbjct: 1358 ENGYTA----NDCVERI--KPDEQRACE-SGPCPQWAYGNWGECTKLCGGGIRTRLVVCQ 1410
Query: 478 QKNNGRINVLSDDECSEEKPLDRQPCELEPC-EGVDWMVSEWTGCD-TCLATVRSRVAQC 535
+ N R LS + +KP DR+ C C W W+ C +C + R C
Sbjct: 1411 RSNGERFPDLSCEIL--DKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYC 1468
Query: 536 VTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ KD + S +C + P C + P +W A WS+CSV CG G + R V C
Sbjct: 1469 MAKDGSHLESDYCKHLAKPHGHRKCRGGRCP----KWKAGAWSQCSVSCGRGVQQRHVGC 1524
Query: 596 GKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP-SKWYAAPWSECTKSCGKGLRFRS 654
+ + + ++ C + + C+ P +CP W A W ECTK+CG+G R+R
Sbjct: 1525 -QIGTHKIAR--ETECNPYTRPESERDCQGP--RCPLYTWRAEEWQECTKTCGEGSRYRK 1579
Query: 655 VVCLRGGK---EFSDCPKKSLPDSAGSCNEQSCE 685
VVC+ K + C P SC+ Q CE
Sbjct: 1580 VVCVDDNKNEVHGARCDVSKRPVDRESCSLQPCE 1613
Score = 155 bits (377), Expect = 1e-36
Identities = 116/408 (28%), Positives = 165/408 (40%), Gaps = 65/408 (15%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W + ++ CS +C GG Q R C + +V+D+ C K T Q C+ CP QW
Sbjct: 1001 WRYSAWTECSKSCDGGTQRRRAICVNTRN-DVLDDSKCTHQEK-VTIQRCSEFPCP-QWK 1057
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G+WS C CGK G + R+V C+ G ++D+ C KP ++C C
Sbjct: 1058 SGDWSECLVTCGK-GHKHRQVWCQF----G-EDRLNDRMCDP--ETKPTSMQTCQ-QPEC 1108
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCE 509
+W PW C CG G Q R V C ++V+ D++C+ +P D Q CEL C
Sbjct: 1109 ASWQAGPWGQCSVTCGQGYQLRAVKCIIGTY--MSVVDDNDCNAATRPTDTQDCELPSCH 1166
Query: 510 G----------------VDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHP 552
W WT C TC R R C ++ V + S C+ P
Sbjct: 1167 PPPAAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLP 1226
Query: 553 TPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASV--MKVDDSN 610
P +E C + C QW A WS CSV CG G+ TR+V C + + + D
Sbjct: 1227 RPVAKEECS---VTPCG-QWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDY 1282
Query: 611 CPKEEKYNDSKPCEV------------------PEEKCPSK--------WYAAPWSECTK 644
P+ ++ PC P PS+ W PW C+
Sbjct: 1283 IPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSS 1342
Query: 645 SCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+C G + R VVC G +DC ++ PD +C C G+
Sbjct: 1343 TCAGGSQRRVVVCQDENGYTANDCVERIKPDEQRACESGPCPQWAYGN 1390
Score = 151 bits (367), Expect = 2e-35
Identities = 112/387 (28%), Positives = 159/387 (41%), Gaps = 47/387 (12%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREEL----EVVDEGLCDDGLKPATNQTCNTQACP 386
W + S CSA CG G ++ D+ C L E VD+G C KP+ + C+ +
Sbjct: 939 WHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNT 998
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV 446
W W+ CSK C GT+ R C N V+DD +C + + C+
Sbjct: 999 GGWRYSAWTECSKSCD-GGTQRRRAIC----VNTRNDVLDDSKCTH---QEKVTIQRCS- 1049
Query: 447 DAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCEL 505
+ CP W W C CG G + RQV C Q R+N D C E KP Q C+
Sbjct: 1050 EFPCPQWKSGDWSECLVTCGKGHKHRQVWC-QFGEDRLN---DRMCDPETKPTSMQTCQQ 1105
Query: 506 EPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYR-VVNSSFC--------------- 548
C W W C TC + R +C+ Y VV+ + C
Sbjct: 1106 PEC--ASWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELP 1163
Query: 549 SYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDD 608
S HP PA E + A + QW W+ CS CG G + R V C +G+ D+
Sbjct: 1164 SCHPPPAAPET-RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVA---DE 1219
Query: 609 SNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGK---EFS 665
S C + + C V C +W A WS C+ +CG+G R V+C+ + S
Sbjct: 1220 SACATLPRPVAKEECSVTP--C-GQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRS 1276
Query: 666 DCPKKSLPDSAGSCNEQSCEALGEGSG 692
+C + +P++ C+ C SG
Sbjct: 1277 ECDQDYIPETDQDCSMSPCPQRTPDSG 1303
Score = 111 bits (266), Expect = 3e-23
Identities = 69/197 (35%), Positives = 89/197 (45%), Gaps = 29/197 (14%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP-- 387
SW G + CS TCG G Q R V C + VVD+ C+ +P Q C +C P
Sbjct: 1110 SWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPP 1169
Query: 388 ---------------QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFD 432
QW G+W+ CS CGK GTR R V C NG SV D+ C
Sbjct: 1170 AAPETRRSTYSAPRTQWRFGSWTPCSATCGK-GTRMRYVSCRD--ENG--SVADESACAT 1224
Query: 433 LLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
L P+P E C+V C W W C CG G+ TRQV+C ++ +V+ EC
Sbjct: 1225 L--PRPVAKEECSV-TPCGQWKALDWSSCSVTCGQGRATRQVMCVNYSD---HVIDRSEC 1278
Query: 493 SEEK-PLDRQPCELEPC 508
++ P Q C + PC
Sbjct: 1279 DQDYIPETDQDCSMSPC 1295
Score = 90.6 bits (215), Expect = 5e-17
Identities = 57/189 (30%), Positives = 80/189 (42%), Gaps = 9/189 (4%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y+W + C+ TCG G + R V C + EV CD +P ++C+ Q C
Sbjct: 1557 YTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEV-HGARCDVSKRPVDRESCSLQPCEYV 1615
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W+ G WS CS CGK G + R V C +I T + + G +P C +
Sbjct: 1616 WITGEWSECSVTCGK-GYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYL-R 1673
Query: 449 ACP---TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ--PC 503
CP TW + W C CG G R V C + ++ D EE+ R C
Sbjct: 1674 DCPVSATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQPSHLCHTDLKPEERKTCRNVYNC 1733
Query: 504 EL-EPCEGV 511
EL + C+ V
Sbjct: 1734 ELPQNCKEV 1742
>AB037733-1|BAA92550.1| 1471|Homo sapiens KIAA1312 protein protein.
Length = 1471
Score = 327 bits (804), Expect = 2e-88
Identities = 214/665 (32%), Positives = 315/665 (47%), Gaps = 63/665 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN- 115
CSRTCGGG+ + R C P NG C G K+ SC T+ C + DFR EQCA ++
Sbjct: 442 CSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDG 501
Query: 116 ---NVTFRGKKYRWVPY---LKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
N+ RWVP + + C+L C G+ YY+ +++VIDGT C D+ D+C
Sbjct: 502 KHFNINGLLPNVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDIC 561
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGAT 229
V G+C+ GCD +L S A+ DKC C G+ +C T NT + GYN ++ IP GAT
Sbjct: 562 VQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNT--VHYGYNTVVRIPAGAT 619
Query: 230 TIYITEIEPS-----NNYLALRSKNGTYYLNGDYHIDF-PRSMTIAGALWNYERNQQGIT 283
I + + S +NYLAL S G + LNG++ + R + I A+ Y ++ T
Sbjct: 620 NIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSE---T 676
Query: 284 APDKLRSLGPINEPLYLSLLLIDE--NVGVEYEYSLPIEKAPLPTQRYSW-VHGNFSSCS 340
A +++ S I + L L +L + + N V Y +++PIE P Q++ W HG + +CS
Sbjct: 677 AVERINSTDRIEQELLLQVLSVGKLYNPDVRYSFNIPIEDKP---QQFYWNSHGPWQACS 733
Query: 341 ATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACPPQWVPGNWSRCSK 399
C G + + V R ++L V D+ CD +P + C T C +W + S CS
Sbjct: 734 KPCQGERKRKLVCTRESDQLTVSDQ-RCDRLPQPGHITEPCGTD-CDLRWHVASRSECSA 791
Query: 400 RCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPW 458
+CG G R+ ++ C K +G VDD C PKP+ E C+ + W S W
Sbjct: 792 QCGL-GYRTLDIYCAKYSRLDGKTEKVDDGFCSS--HPKPSNREKCSGECNTGGWRYSAW 848
Query: 459 KPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEW 518
C K C G Q R+ +C N R +VL D +C+ ++ + Q C PC W +W
Sbjct: 849 TECSKSCDGGTQRRRAICV---NTRNDVLDDSKCTHQEKVTIQRCSEFPCP--QWKSGDW 903
Query: 519 TGC-DTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
+ C TC + R C + R +N C P + C + P C W A W
Sbjct: 904 SECLVTCGKGHKHRQVWCQFGEDR-LNDRMCDPETKPTSMQTCQQ---PEC-ASWQAGPW 958
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP------ 631
+CSV CG G + R V C G + VDD++C + D++ CE+P P
Sbjct: 959 GQCSVTCGQGYQLRAVKC--IIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPET 1016
Query: 632 ---------SKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD---CPKKSLPDSAGSC 679
++W W+ C+ +CGKG R R V C +D C P + C
Sbjct: 1017 RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLPRPVAKEEC 1076
Query: 680 NEQSC 684
+ C
Sbjct: 1077 SVTPC 1081
Score = 156 bits (379), Expect = 7e-37
Identities = 117/394 (29%), Positives = 165/394 (41%), Gaps = 61/394 (15%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLC---------------------- 368
W ++SSCS TCG G +R V C + + V+D C
Sbjct: 1084 WKALDWSSCSVTCGQGRATRQVMCVNYSD-HVIDRSECDQDYIPETDQDCSMSPCPQRTP 1142
Query: 369 DDGLK--PATNQTCNTQACPP---------QWVPGNWSRCSKRCGKDGTRSREVRCEKII 417
D GL P N+ ++ P QW G W CS C G++ R V C+
Sbjct: 1143 DSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCA-GGSQRRVVVCQD-- 1199
Query: 418 TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCY 477
NG + +C + + KP +C CP W W C KLCG G +TR VVC
Sbjct: 1200 ENGYTA----NDCVERI--KPDEQRACE-SGPCPQWAYGNWGECTKLCGGGIRTRLVVCQ 1252
Query: 478 QKNNGRINVLSDDECSEEKPLDRQPCELEPC-EGVDWMVSEWTGCD-TCLATVRSRVAQC 535
+ N R LS + +KP DR+ C C W W+ C +C + R C
Sbjct: 1253 RSNGERFPDLSCEIL--DKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYC 1310
Query: 536 VTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ KD + S +C + P C + P +W A WS+CSV CG G + R V C
Sbjct: 1311 MAKDGSHLESDYCKHLAKPHGHRKCRGGRCP----KWKAGAWSQCSVSCGRGVQQRHVGC 1366
Query: 596 GKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP-SKWYAAPWSECTKSCGKGLRFRS 654
+ + + ++ C + + C+ P +CP W A W ECTK+CG+G R+R
Sbjct: 1367 -QIGTHKIAR--ETECNPYTRPESERDCQGP--RCPLYTWRAEEWQECTKTCGEGSRYRK 1421
Query: 655 VVCLRGGK---EFSDCPKKSLPDSAGSCNEQSCE 685
VVC+ K + C P SC+ Q CE
Sbjct: 1422 VVCVDDNKNEVHGARCDVSKRPVDRESCSLQPCE 1455
Score = 155 bits (377), Expect = 1e-36
Identities = 116/408 (28%), Positives = 165/408 (40%), Gaps = 65/408 (15%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W + ++ CS +C GG Q R C + +V+D+ C K T Q C+ CP QW
Sbjct: 843 WRYSAWTECSKSCDGGTQRRRAICVNTRN-DVLDDSKCTHQEK-VTIQRCSEFPCP-QWK 899
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G+WS C CGK G + R+V C+ G ++D+ C KP ++C C
Sbjct: 900 SGDWSECLVTCGK-GHKHRQVWCQF----G-EDRLNDRMCDP--ETKPTSMQTCQ-QPEC 950
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCE 509
+W PW C CG G Q R V C ++V+ D++C+ +P D Q CEL C
Sbjct: 951 ASWQAGPWGQCSVTCGQGYQLRAVKCIIGTY--MSVVDDNDCNAATRPTDTQDCELPSCH 1008
Query: 510 G----------------VDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHP 552
W WT C TC R R C ++ V + S C+ P
Sbjct: 1009 PPPAAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLP 1068
Query: 553 TPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASV--MKVDDSN 610
P +E C + C QW A WS CSV CG G+ TR+V C + + + D
Sbjct: 1069 RPVAKEECS---VTPCG-QWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDY 1124
Query: 611 CPKEEKYNDSKPCEV------------------PEEKCPSK--------WYAAPWSECTK 644
P+ ++ PC P PS+ W PW C+
Sbjct: 1125 IPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSS 1184
Query: 645 SCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+C G + R VVC G +DC ++ PD +C C G+
Sbjct: 1185 TCAGGSQRRVVVCQDENGYTANDCVERIKPDEQRACESGPCPQWAYGN 1232
Score = 151 bits (367), Expect = 2e-35
Identities = 112/387 (28%), Positives = 159/387 (41%), Gaps = 47/387 (12%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREEL----EVVDEGLCDDGLKPATNQTCNTQACP 386
W + S CSA CG G ++ D+ C L E VD+G C KP+ + C+ +
Sbjct: 781 WHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNT 840
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV 446
W W+ CSK C GT+ R C N V+DD +C + + C+
Sbjct: 841 GGWRYSAWTECSKSCD-GGTQRRRAIC----VNTRNDVLDDSKCTH---QEKVTIQRCS- 891
Query: 447 DAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCEL 505
+ CP W W C CG G + RQV C Q R+N D C E KP Q C+
Sbjct: 892 EFPCPQWKSGDWSECLVTCGKGHKHRQVWC-QFGEDRLN---DRMCDPETKPTSMQTCQQ 947
Query: 506 EPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYR-VVNSSFC--------------- 548
C W W C TC + R +C+ Y VV+ + C
Sbjct: 948 PEC--ASWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELP 1005
Query: 549 SYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDD 608
S HP PA E + A + QW W+ CS CG G + R V C +G+ D+
Sbjct: 1006 SCHPPPAAPET-RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVA---DE 1061
Query: 609 SNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGK---EFS 665
S C + + C V C +W A WS C+ +CG+G R V+C+ + S
Sbjct: 1062 SACATLPRPVAKEECSVTP--C-GQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRS 1118
Query: 666 DCPKKSLPDSAGSCNEQSCEALGEGSG 692
+C + +P++ C+ C SG
Sbjct: 1119 ECDQDYIPETDQDCSMSPCPQRTPDSG 1145
Score = 150 bits (363), Expect = 6e-35
Identities = 96/316 (30%), Positives = 137/316 (43%), Gaps = 29/316 (9%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W G + +CS+TC GG Q R V C+ D C + +KP + C + C PQW
Sbjct: 1174 WRTGPWGACSSTCAGGSQRRVVVCQDENGYTAND---CVERIKPDEQRACESGPC-PQWA 1229
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
GNW C+K CG G R+R V C++ +NG D C ++L KP E CN AC
Sbjct: 1230 YGNWGECTKLCG-GGIRTRLVVCQR--SNG--ERFPDLSC-EIL-DKPPDREQCNTH-AC 1281
Query: 451 P---TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELE 506
P W PW C CG G + R V C K+ L D C KP + C
Sbjct: 1282 PHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSH---LESDYCKHLAKPHGHRKCRGG 1338
Query: 507 PCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
C W W+ C +C V+ R C +++ + C+ + P E C +
Sbjct: 1339 RCP--KWKAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRC 1396
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
P W A +W +C+ CG G + R+V C D + +V + C ++ D + C +
Sbjct: 1397 PL--YTWRAEEWQECTKTCGEGSRYRKVVCVD-DNKN--EVHGARCDVSKRPVDRESCSL 1451
Query: 626 PEEKCPSKWYAAPWSE 641
+ C W WSE
Sbjct: 1452 --QPCEYVWITGEWSE 1465
Score = 126 bits (304), Expect = 9e-28
Identities = 83/264 (31%), Positives = 111/264 (42%), Gaps = 23/264 (8%)
Query: 320 EKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQT 379
E P P W +GN+ C+ CGGGI++R V C+ R E + C+ KP +
Sbjct: 1221 ESGPCP----QWAYGNWGECTKLCGGGIRTRLVVCQ-RSNGERFPDLSCEILDKPPDREQ 1275
Query: 380 CNTQACP--PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CNT ACP W G WS CS CG+ G + R V C + +G S ++ C L K
Sbjct: 1276 CNTHACPHDAAWSTGPWSSCSVSCGR-GHKQRNVYC--MAKDG--SHLESDYCKHL--AK 1328
Query: 438 PALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EK 496
P + C CP W W C CG G Q R V C G + + EC+ +
Sbjct: 1329 PHGHRKCR-GGRCPKWKAGAWSQCSVSCGRGVQQRHVGC---QIGTHKIARETECNPYTR 1384
Query: 497 PLDRQPCELEPCEGVDWMVSEWTGC-DTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPA 555
P + C+ C W EW C TC R R CV + V+ + C P
Sbjct: 1385 PESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARCDVSKRPV 1444
Query: 556 LEEPCDKDKLPACQVQWYATQWSK 579
E C L C+ W +WS+
Sbjct: 1445 DRESC---SLQPCEYVWITGEWSE 1465
Score = 111 bits (266), Expect = 3e-23
Identities = 69/197 (35%), Positives = 89/197 (45%), Gaps = 29/197 (14%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP-- 387
SW G + CS TCG G Q R V C + VVD+ C+ +P Q C +C P
Sbjct: 952 SWQAGPWGQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPP 1011
Query: 388 ---------------QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFD 432
QW G+W+ CS CGK GTR R V C NG SV D+ C
Sbjct: 1012 AAPETRRSTYSAPRTQWRFGSWTPCSATCGK-GTRMRYVSCRD--ENG--SVADESACAT 1066
Query: 433 LLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
L P+P E C+V C W W C CG G+ TRQV+C ++ +V+ EC
Sbjct: 1067 L--PRPVAKEECSV-TPCGQWKALDWSSCSVTCGQGRATRQVMCVNYSD---HVIDRSEC 1120
Query: 493 SEEK-PLDRQPCELEPC 508
++ P Q C + PC
Sbjct: 1121 DQDYIPETDQDCSMSPC 1137
>AF488803-1|AAO15765.1| 1935|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motifs 9B
protein.
Length = 1935
Score = 326 bits (802), Expect = 4e-88
Identities = 214/665 (32%), Positives = 315/665 (47%), Gaps = 63/665 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN- 115
CSRTCGGG+ + R C P NG C G K+ SC T+ C + DFR EQCA ++
Sbjct: 600 CSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDG 659
Query: 116 ---NVTFRGKKYRWVPY---LKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
N+ RWVP + + C+L C G+ YY+ +++VIDGT C D+ D+C
Sbjct: 660 KHFNINGLLPNVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDIC 719
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGAT 229
V G+C+ GCD +L S A+ DKC C G+ +C T NT + GYN ++ IP GAT
Sbjct: 720 VQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNT--VHYGYNTVVRIPAGAT 777
Query: 230 TIYITEIEPS-----NNYLALRSKNGTYYLNGDYHIDF-PRSMTIAGALWNYERNQQGIT 283
I + + S +NYLAL S G + LNG++ + R + I A+ Y ++ T
Sbjct: 778 NIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSE---T 834
Query: 284 APDKLRSLGPINEPLYLSLLLIDE--NVGVEYEYSLPIEKAPLPTQRYSW-VHGNFSSCS 340
A +++ S I + L L +L + + N V Y +++PIE P Q++ W HG + +CS
Sbjct: 835 AVERINSTDRIEQELLLQVLSVGKLYNPDVRYSFNIPIEDKP---QQFYWNSHGPWQACS 891
Query: 341 ATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACPPQWVPGNWSRCSK 399
C G + + V R ++L V D+ CD +P + C T C +W + S CS
Sbjct: 892 KPCQGERKRKLVCTRESDQLTVSDQ-RCDRLPQPGHITEPCGTD-CDLRWHVASRSECSA 949
Query: 400 RCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPW 458
+CG G R+ ++ C K +G VDD C PKP+ E C+ + W S W
Sbjct: 950 QCGL-GYRTLDIYCAKYSRLDGKTEKVDDGFCSS--HPKPSNREKCSGECNTGGWRYSAW 1006
Query: 459 KPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEW 518
C K C G Q R+ +C N R +VL D +C+ ++ + Q C PC W +W
Sbjct: 1007 TECSKSCDGGTQRRRAICV---NTRNDVLDDSKCTHQEKVTIQRCSEFPCP--QWKSGDW 1061
Query: 519 TGC-DTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
+ C TC + R C + R +N C P + C + P C W A W
Sbjct: 1062 SECLVTCGKGHKHRQVWCQFGEDR-LNDRMCDPETKPTSMQTCQQ---PEC-ASWQAGPW 1116
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP------ 631
+CSV CG G + R V C G + VDD++C + D++ CE+P P
Sbjct: 1117 VQCSVTCGQGYQLRAVKC--IIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPPAAPET 1174
Query: 632 ---------SKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD---CPKKSLPDSAGSC 679
++W W+ C+ +CGKG R R V C +D C P + C
Sbjct: 1175 RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLPRPVAKEEC 1234
Query: 680 NEQSC 684
+ C
Sbjct: 1235 SVTPC 1239
Score = 175 bits (425), Expect = 2e-42
Identities = 119/376 (31%), Positives = 159/376 (42%), Gaps = 30/376 (7%)
Query: 320 EKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQT 379
E P P W +GN+ C+ CGGGI++R V C+ R E + C+ KP +
Sbjct: 1379 ESGPCP----QWAYGNWGECTKLCGGGIRTRLVVCQ-RSNGERFPDLSCEILDKPPDREQ 1433
Query: 380 CNTQACPPQ--WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CNT ACP W G WS CS CG+ G + R V C + +G S ++ C L K
Sbjct: 1434 CNTHACPHDAAWSTGPWSSCSVSCGR-GHKQRNVYC--MAKDG--SHLESDYCKHLA--K 1486
Query: 438 PALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EK 496
P + C CP W W C CG G Q R V C G + + EC+ +
Sbjct: 1487 PHGHRKCR-GGRCPKWKAGAWSQCSVSCGRGVQQRHVGC---QIGTHKIARETECNPYTR 1542
Query: 497 PLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPA 555
P + C+ C W EW C TC R R CV + V+ + C P
Sbjct: 1543 PESERDCQGPRCPLYTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEVHGARCDVSKRPV 1602
Query: 556 LEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGK-FDGASVMKVD---DSNC 611
E C L C+ W +WS+CSV CG G K R V C + + G + NC
Sbjct: 1603 DRESCS---LQPCEYVWITGEWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINC 1659
Query: 612 PKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD-CPKK 670
P + PC + E + W W C+ SCG G+ RSV CL + S C
Sbjct: 1660 PGTQP-PSVHPCYLRECPVSATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQPSHLCHTD 1718
Query: 671 SLPDSAGSC-NEQSCE 685
P+ +C N +CE
Sbjct: 1719 LKPEERKTCRNVYNCE 1734
Score = 169 bits (411), Expect = 9e-41
Identities = 107/340 (31%), Positives = 152/340 (44%), Gaps = 31/340 (9%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W G + +CS+TC GG Q R V C+ D C + +KP + C + C PQW
Sbjct: 1332 WRTGPWGACSSTCAGGSQRRVVVCQDENGYTAND---CVERIKPDEQRACESGPC-PQWA 1387
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
GNW C+K CG G R+R V C++ +NG D C ++L KP E CN AC
Sbjct: 1388 YGNWGECTKLCG-GGIRTRLVVCQR--SNG--ERFPDLSC-EIL-DKPPDREQCNTH-AC 1439
Query: 451 P---TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELE 506
P W PW C CG G + R V C K+ L D C KP + C
Sbjct: 1440 PHDAAWSTGPWSSCSVSCGRGHKQRNVYCMAKDGSH---LESDYCKHLAKPHGHRKCRGG 1496
Query: 507 PCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
C W W+ C +C V+ R C +++ + C+ + P E C +
Sbjct: 1497 RCP--KWKAGAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRC 1554
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
P W A +W +C+ CG G + R+V C D + +V + C ++ D + C +
Sbjct: 1555 PL--YTWRAEEWQECTKTCGEGSRYRKVVCVD-DNKN--EVHGARCDVSKRPVDRESCSL 1609
Query: 626 PEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC--LRGGKE 663
+ C W WSEC+ +CGKG + R V C + GKE
Sbjct: 1610 --QPCEYVWITGEWSECSVTCGKGYKQRLVSCSEIYTGKE 1647
Score = 156 bits (379), Expect = 7e-37
Identities = 117/394 (29%), Positives = 165/394 (41%), Gaps = 61/394 (15%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLC---------------------- 368
W ++SSCS TCG G +R V C + + V+D C
Sbjct: 1242 WKALDWSSCSVTCGQGRATRQVMCVNYSD-HVIDRSECDQDYIPETDQDCSMSPCPQRTP 1300
Query: 369 DDGLK--PATNQTCNTQACPP---------QWVPGNWSRCSKRCGKDGTRSREVRCEKII 417
D GL P N+ ++ P QW G W CS C G++ R V C+
Sbjct: 1301 DSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCA-GGSQRRVVVCQD-- 1357
Query: 418 TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCY 477
NG + +C + + KP +C CP W W C KLCG G +TR VVC
Sbjct: 1358 ENGYTA----NDCVERI--KPDEQRACE-SGPCPQWAYGNWGECTKLCGGGIRTRLVVCQ 1410
Query: 478 QKNNGRINVLSDDECSEEKPLDRQPCELEPC-EGVDWMVSEWTGCD-TCLATVRSRVAQC 535
+ N R LS + +KP DR+ C C W W+ C +C + R C
Sbjct: 1411 RSNGERFPDLSCEIL--DKPPDREQCNTHACPHDAAWSTGPWSSCSVSCGRGHKQRNVYC 1468
Query: 536 VTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ KD + S +C + P C + P +W A WS+CSV CG G + R V C
Sbjct: 1469 MAKDGSHLESDYCKHLAKPHGHRKCRGGRCP----KWKAGAWSQCSVSCGRGVQQRHVGC 1524
Query: 596 GKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP-SKWYAAPWSECTKSCGKGLRFRS 654
+ + + ++ C + + C+ P +CP W A W ECTK+CG+G R+R
Sbjct: 1525 -QIGTHKIAR--ETECNPYTRPESERDCQGP--RCPLYTWRAEEWQECTKTCGEGSRYRK 1579
Query: 655 VVCLRGGK---EFSDCPKKSLPDSAGSCNEQSCE 685
VVC+ K + C P SC+ Q CE
Sbjct: 1580 VVCVDDNKNEVHGARCDVSKRPVDRESCSLQPCE 1613
Score = 155 bits (377), Expect = 1e-36
Identities = 116/408 (28%), Positives = 165/408 (40%), Gaps = 65/408 (15%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W + ++ CS +C GG Q R C + +V+D+ C K T Q C+ CP QW
Sbjct: 1001 WRYSAWTECSKSCDGGTQRRRAICVNTRN-DVLDDSKCTHQEK-VTIQRCSEFPCP-QWK 1057
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G+WS C CGK G + R+V C+ G ++D+ C KP ++C C
Sbjct: 1058 SGDWSECLVTCGK-GHKHRQVWCQF----G-EDRLNDRMCDP--ETKPTSMQTCQ-QPEC 1108
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCE 509
+W PW C CG G Q R V C ++V+ D++C+ +P D Q CEL C
Sbjct: 1109 ASWQAGPWVQCSVTCGQGYQLRAVKCIIGTY--MSVVDDNDCNAATRPTDTQDCELPSCH 1166
Query: 510 G----------------VDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHP 552
W WT C TC R R C ++ V + S C+ P
Sbjct: 1167 PPPAAPETRRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVADESACATLP 1226
Query: 553 TPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASV--MKVDDSN 610
P +E C + C QW A WS CSV CG G+ TR+V C + + + D
Sbjct: 1227 RPVAKEECS---VTPCG-QWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRSECDQDY 1282
Query: 611 CPKEEKYNDSKPCEV------------------PEEKCPSK--------WYAAPWSECTK 644
P+ ++ PC P PS+ W PW C+
Sbjct: 1283 IPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSS 1342
Query: 645 SCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+C G + R VVC G +DC ++ PD +C C G+
Sbjct: 1343 TCAGGSQRRVVVCQDENGYTANDCVERIKPDEQRACESGPCPQWAYGN 1390
Score = 152 bits (369), Expect = 1e-35
Identities = 112/387 (28%), Positives = 159/387 (41%), Gaps = 47/387 (12%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREEL----EVVDEGLCDDGLKPATNQTCNTQACP 386
W + S CSA CG G ++ D+ C L E VD+G C KP+ + C+ +
Sbjct: 939 WHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGECNT 998
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV 446
W W+ CSK C GT+ R C N V+DD +C + + C+
Sbjct: 999 GGWRYSAWTECSKSCD-GGTQRRRAIC----VNTRNDVLDDSKCTH---QEKVTIQRCS- 1049
Query: 447 DAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCEL 505
+ CP W W C CG G + RQV C Q R+N D C E KP Q C+
Sbjct: 1050 EFPCPQWKSGDWSECLVTCGKGHKHRQVWC-QFGEDRLN---DRMCDPETKPTSMQTCQQ 1105
Query: 506 EPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYR-VVNSSFC--------------- 548
C W W C TC + R +C+ Y VV+ + C
Sbjct: 1106 PEC--ASWQAGPWVQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELP 1163
Query: 549 SYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDD 608
S HP PA E + A + QW W+ CS CG G + R V C +G+ D+
Sbjct: 1164 SCHPPPAAPET-RRSTYSAPRTQWRFGSWTPCSATCGKGTRMRYVSCRDENGSVA---DE 1219
Query: 609 SNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGK---EFS 665
S C + + C V C +W A WS C+ +CG+G R V+C+ + S
Sbjct: 1220 SACATLPRPVAKEECSVTP--C-GQWKALDWSSCSVTCGQGRATRQVMCVNYSDHVIDRS 1276
Query: 666 DCPKKSLPDSAGSCNEQSCEALGEGSG 692
+C + +P++ C+ C SG
Sbjct: 1277 ECDQDYIPETDQDCSMSPCPQRTPDSG 1303
Score = 110 bits (264), Expect = 6e-23
Identities = 69/197 (35%), Positives = 89/197 (45%), Gaps = 29/197 (14%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP-- 387
SW G + CS TCG G Q R V C + VVD+ C+ +P Q C +C P
Sbjct: 1110 SWQAGPWVQCSVTCGQGYQLRAVKCIIGTYMSVVDDNDCNAATRPTDTQDCELPSCHPPP 1169
Query: 388 ---------------QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFD 432
QW G+W+ CS CGK GTR R V C NG SV D+ C
Sbjct: 1170 AAPETRRSTYSAPRTQWRFGSWTPCSATCGK-GTRMRYVSCRD--ENG--SVADESACAT 1224
Query: 433 LLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
L P+P E C+V C W W C CG G+ TRQV+C ++ +V+ EC
Sbjct: 1225 L--PRPVAKEECSV-TPCGQWKALDWSSCSVTCGQGRATRQVMCVNYSD---HVIDRSEC 1278
Query: 493 SEEK-PLDRQPCELEPC 508
++ P Q C + PC
Sbjct: 1279 DQDYIPETDQDCSMSPC 1295
Score = 91.1 bits (216), Expect = 4e-17
Identities = 57/189 (30%), Positives = 80/189 (42%), Gaps = 9/189 (4%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y+W + C+ TCG G + R V C + EV CD +P ++C+ Q C
Sbjct: 1557 YTWRAEEWQECTKTCGEGSRYRKVVCVDDNKNEV-HGARCDVSKRPVDRESCSLQPCEYV 1615
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W+ G WS CS CGK G + R V C +I T + + G +P C +
Sbjct: 1616 WITGEWSECSVTCGK-GYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYL-R 1673
Query: 449 ACP---TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ--PC 503
CP TW + W C CG G R V C + ++ D EE+ R C
Sbjct: 1674 ECPVSATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQPSHLCHTDLKPEERKTCRNVYNC 1733
Query: 504 EL-EPCEGV 511
EL + C+ V
Sbjct: 1734 ELPQNCKEV 1742
>AJ311903-1|CAC83612.1| 1081|Homo sapiens ADAMTS18 protein protein.
Length = 1081
Score = 320 bits (787), Expect = 3e-86
Identities = 176/475 (37%), Positives = 247/475 (52%), Gaps = 26/475 (5%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV Q+R C P G C G Y C C ENSLDFRA+QCA+YN+
Sbjct: 600 CSRTCGGGVKFQERHCNNPKPQYGGIFCPGSSRIYQLCNINPCNENSLDFRAQQCAEYNS 659
Query: 117 VTFRGKKYRWVPYLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVC 174
FRG Y+W PY KV + C+L C F++ KV DGT C+ + DVC+DGVC
Sbjct: 660 KPFRGWFYQWKPYTKVEEEDRCKLYCKAENFEFFFAMSGKVKDGTPCSPNKNDVCIDGVC 719
Query: 175 QPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYIT 234
+ VGCD LGS A D C C+G+ C K L Q Y ++LIP GA +I I
Sbjct: 720 ELVGCDHELGSKAVSDACGVCKGDNSTCKFYKGLYLNQHKANEYYPVVLIPAGARSIEIQ 779
Query: 235 EIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPI 294
E++ S++YLA+RS + YYL G + ID+P AG + Y+R+ P++L + GP
Sbjct: 780 ELQVSSSYLAVRSLSQKYYLTGGWSIDWPGEFPFAGTTFEYQRS---FNRPERLYAPGPT 836
Query: 295 NEPLYLSLLLIDENVGVEYEYSLP--IEKAPLPTQR--YSWVHGNFSSCSATCGGGIQSR 350
NE L +L+ +N G+ ++Y+LP + P T+R Y+W S CS +CGGG +
Sbjct: 837 NETLVFEILMQGKNPGIAWKYALPKVMNGTPPATKRPAYTWSIVQ-SECSVSCGGGYINV 895
Query: 351 DVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSRCSKRCGKDGTRSR 409
C R++ V+ C KP T + CN +CP W+PG WS CSK C G +SR
Sbjct: 896 KAIC-LRDQNTQVNSSFCSAKTKPVTEPKICNAFSCPAYWMPGEWSTCSKSCA-GGQQSR 953
Query: 410 EVRCEKIITNGLPSVVDDKECFDLLG-PKPALYESCNVDAACPTWFISPWKPCDKLCGSG 468
+++C P ++ L P ++CN A P W + PW C K CG G
Sbjct: 954 KIQC----VQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLGPWSQCSKTCGRG 1009
Query: 469 QQTRQVVCYQKNNGRINVLSDDEC-SEEKPLDRQPCELEPC---EGVDWMVSEWT 519
+ R+++C L + +C S +P ++ C L C + W+ S W+
Sbjct: 1010 VRKRELLC---KGSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRLQWVASSWS 1061
Score = 77.0 bits (181), Expect = 7e-13
Identities = 48/152 (31%), Positives = 66/152 (43%), Gaps = 11/152 (7%)
Query: 533 AQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWYATQWSKCSVECGVGKKTR 591
A C+ VNSSFCS P E C+ PA W +WS CS C G+++R
Sbjct: 897 AICLRDQNTQVNSSFCSAKTKPVTEPKICNAFSCPA---YWMPGEWSTCSKSCAGGQQSR 953
Query: 592 RVFC-GKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGL 650
++ C K V S CP + C CP +W PWS+C+K+CG+G+
Sbjct: 954 KIQCVQKKPFQKEEAVLHSLCPVSTP-TQVQACN--SHACPPQWSLGPWSQCSKTCGRGV 1010
Query: 651 RFRSVVCLRGGKEF---SDCPKKSLPDSAGSC 679
R R ++C E S C P+ C
Sbjct: 1011 RKRELLCKGSAAETLPESQCTSLPRPELQEGC 1042
Score = 75.4 bits (177), Expect = 2e-12
Identities = 43/140 (30%), Positives = 59/140 (42%), Gaps = 6/140 (4%)
Query: 444 CNVDAACPT-WFISPWKPCDKLCGSGQQTRQVVCYQKNN-GRINVLSDDECSEEKPLDRQ 501
CN +CP W W C K C GQQ+R++ C QK + + C P Q
Sbjct: 925 CNA-FSCPAYWMPGEWSTCSKSCAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQ 983
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C C W + W+ C TC VR R C + S C+ P P L+E C
Sbjct: 984 ACNSHACPP-QWSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGC 1042
Query: 561 DKDKLPA-CQVQWYATQWSK 579
+ P ++QW A+ WS+
Sbjct: 1043 VLGRCPKNSRLQWVASSWSE 1062
Score = 52.4 bits (120), Expect = 2e-05
Identities = 38/121 (31%), Positives = 53/121 (43%), Gaps = 15/121 (12%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNC-PKEEKYNDSKPCEVPEEKC 630
W Q S+CSV CG G + C + +V+ S C K + + K C C
Sbjct: 877 WSIVQ-SECSVSCGGGYINVKAICLRDQNT---QVNSSFCSAKTKPVTEPKICNA--FSC 930
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVCLRG---GKE----FSDCPKKSLPDSAGSCNEQS 683
P+ W WS C+KSC G + R + C++ KE S CP S P +CN +
Sbjct: 931 PAYWMPGEWSTCSKSCAGGQQSRKIQCVQKKPFQKEEAVLHSLCP-VSTPTQVQACNSHA 989
Query: 684 C 684
C
Sbjct: 990 C 990
>AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 1593
Score = 305 bits (750), Expect = 8e-82
Identities = 168/461 (36%), Positives = 245/461 (53%), Gaps = 29/461 (6%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG GV S +R+C P G CTG +Y C C + FR QC++++
Sbjct: 554 CSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTFRQMQCSEFDT 613
Query: 117 VTFRGKKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC--NDDSFDVCVDGVC 174
V ++ + Y W P + PCEL C +F + + VIDGT C +S +VC++G+C
Sbjct: 614 VPYKNELYHWFPIFNPAHPCELYCRPIDGQFSEKMLDAVIDGTPCFEGGNSRNVCINGIC 673
Query: 175 QPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYIT 234
+ VGCD + SNA ED+C C G+G +C T +K+ ++ GY DI LIP+GA I +
Sbjct: 674 KMVGCDYEIDSNATEDRCGVCLGDGSSCQTVRKMFKQKE-GSGYVDIGLIPKGARDIRVM 732
Query: 235 EIEPSNNYLALRSKN-GTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGP 293
EIE + N+LA+RS++ YYLNG + I + + +AG ++ Y+R +KL + GP
Sbjct: 733 EIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGD----LEKLMATGP 788
Query: 294 INEPLYLSLLLIDENVGVEYEYSLPIEKAPLPT---QRYSWVHGNFSSCSATCGGGIQSR 350
NE +++ LL N G++YEY+ I+K L Q Y W +G+++ CS TCG GI+ +
Sbjct: 789 TNESVWIQLLFQVTNPGIKYEYT--IQKDGLDNDVEQMYFWQYGHWTECSVTCGTGIRRQ 846
Query: 351 DVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSR 409
C ++ +V CD +P Q C+ +ACPP+W G W CS CG G + R
Sbjct: 847 TAHC-IKKGRGMVKATFCDPETQPNGRQKKCHEKACPPRWWAGEWEACSATCGPHGEKKR 905
Query: 410 EVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFISPWKPCDKLCGSG 468
V C + + + + +C LL PK L SCN D CP+ W + W C CG G
Sbjct: 906 TVLCIQTMVSD-EQALPPTDCQHLLKPKTLL--SCNRDILCPSDWTVGNWSECSVSCGGG 962
Query: 469 QQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPCELEPC 508
+ R V C KN+ D+ C KP R C L+ C
Sbjct: 963 VRIRSVTC-AKNH-------DEPCDVTRKPNSRALCGLQQC 995
Score = 103 bits (247), Expect = 7e-21
Identities = 57/174 (32%), Positives = 80/174 (45%), Gaps = 7/174 (4%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W WT C TC +R + A C+ K +V ++FC P + +K AC +
Sbjct: 827 WQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKCHEK--ACPPR 884
Query: 572 WYATQWSKCSVECGV-GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W+A +W CS CG G+K R V C + + + ++C K C + C
Sbjct: 885 WWAGEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCN-RDILC 943
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSC 684
PS W WSEC+ SCG G+R RSV C + E D +K P+S C Q C
Sbjct: 944 PSDWTVGNWSECSVSCGGGVRIRSVTCAKNHDEPCDVTRK--PNSRALCGLQQC 995
Score = 96.3 bits (229), Expect = 1e-18
Identities = 67/236 (28%), Positives = 99/236 (41%), Gaps = 28/236 (11%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W+ GN+S CS TCG G + V C ++ + + C +P + C+ + C W
Sbjct: 1316 WIVGNWSECSTTCGLGAYWKRVECTTQMDSD------CAAIQRPDPAKRCHLRPCAG-WK 1368
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
GNWS+CS+ C G + RE++C + + + C L G P L SCN + C
Sbjct: 1369 VGNWSKCSRNCS-GGFKIREIQC---VDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEP-C 1423
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + PW C + CG G Q R V C G L D ++P C C
Sbjct: 1424 EAWQVEPWSQCSRSCGGGVQERGVFC---PGG----LCD---WTKRPTSTMSCNEHLC-- 1471
Query: 511 VDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRVV---NSSFCSYHPTPALEEPCDK 562
W W C T C + R+ QCV + + C + P P + C++
Sbjct: 1472 CHWATGNWDLCSTSCGGGFQKRIVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQ 1527
Score = 92.7 bits (220), Expect = 1e-17
Identities = 70/244 (28%), Positives = 100/244 (40%), Gaps = 39/244 (15%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGV 511
W + W C CG G ++V C + D +C+ ++P + C L PC G
Sbjct: 1316 WIVGNWSECSTTCGLGAYWKRVECTTQ--------MDSDCAAIQRPDPAKRCHLRPCAG- 1366
Query: 512 DWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFCSYHP--TPALEEPCDKDKLPA 567
W V W+ C C + R QCV ++D+R + C + P L C+ + A
Sbjct: 1367 -WKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEA 1425
Query: 568 CQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPE 627
QV+ WS+CS CG G + R VFC C ++ + C E
Sbjct: 1426 WQVE----PWSQCSRSCGGGVQERGVFC-----------PGGLCDWTKRPTSTMSCN--E 1468
Query: 628 EKCPSKWYAAPWSECTKSCGKGLRFRSVVCL--RGGK-EFSD---CPKKSLPDSAGSCNE 681
C W W C+ SCG G + R V C+ G K E D C K P CN+
Sbjct: 1469 HLC-CHWATGNWDLCSTSCGGGFQKRIVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQ 1527
Query: 682 QSCE 685
Q+C+
Sbjct: 1528 QACK 1531
Score = 80.2 bits (189), Expect = 7e-14
Identities = 60/237 (25%), Positives = 87/237 (36%), Gaps = 29/237 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W+ GNWS CS CG G + V C + D +C + P PA + C++
Sbjct: 1316 WIVGNWSECSTTCGL-GAYWKRVECTTQM---------DSDCAAIQRPDPA--KRCHL-R 1362
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEP 507
C W + W C + C G + R++ C + R + + P C EP
Sbjct: 1363 PCAGWKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEP 1422
Query: 508 CEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLP 566
CE W V W+ C +C V+ R C C + P C++
Sbjct: 1423 CEA--WQVEPWSQCSRSCGGGVQERGVFCP--------GGLCDWTKRPTSTMSCNEHL-- 1470
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C W W CS CG G + R V C +G D C + + + K C
Sbjct: 1471 CCH--WATGNWDLCSTSCGGGFQKRIVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKC 1525
Score = 69.7 bits (163), Expect = 1e-10
Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 14/131 (10%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN 377
P+ + P +W +S CS +CGGG+Q R V C GLCD +P +
Sbjct: 1413 PLSMSCNPEPCEAWQVEPWSQCSRSCGGGVQERGVFCPG---------GLCDWTKRPTST 1463
Query: 378 QTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
+CN C W GNW CS CG G + R V+C + + G D +C P+
Sbjct: 1464 MSCNEHLC-CHWATGNWDLCSTSCG-GGFQKRIVQC--VPSEG-NKTEDQDQCLCDHKPR 1518
Query: 438 PALYESCNVDA 448
P ++ CN A
Sbjct: 1519 PPEFKKCNQQA 1529
Score = 52.8 bits (121), Expect = 1e-05
Identities = 25/57 (43%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSRE--ELEVVDEGLCDDGLKPATNQTCNTQAC 385
W GN+ CS +CGGG Q R V C E + E D+ LCD +P + CN QAC
Sbjct: 1474 WATGNWDLCSTSCGGGFQKRIVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQQAC 1530
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP 386
W GN+S CS +CGGG++ R VTC DE CD KP + C Q CP
Sbjct: 947 WTVGNWSECSVSCGGGVRIRSVTCAKNH-----DEP-CDVTRKPNSRALCGLQQCP 996
>AJ515153-1|CAD56159.3| 1908|Homo sapiens ADAMTS-20 protein protein.
Length = 1908
Score = 301 bits (740), Expect = 1e-80
Identities = 192/636 (30%), Positives = 303/636 (47%), Gaps = 62/636 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN- 115
CSRTCGGG+ S R C P NG C G K+ SC T CP+ + DFR +QC+ +N
Sbjct: 568 CSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNG 627
Query: 116 ---NVTFRGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
+++ RW+P Y V C+L C G ++Y K+ V DGT C ++ D+C
Sbjct: 628 KHLDISGIPSNVRWLPRYSGVGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTETHDIC 687
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGAT 229
V G C GCD +L S+AK DKC C G+ +C T + N+ GYN ++ IP GAT
Sbjct: 688 VQGQCMAAGCDHVLNSSAKIDKCGVCGGDNSSCKTITGVFNSSHY--GYNVVVKIPAGAT 745
Query: 230 TIYITEI----EPSNNYLALRSKNGTYYLNGDYHIDFPRS-MTIAGALWNYERNQQGITA 284
+ I + +P ++YLAL G + NG++ + + + + G + Y + +
Sbjct: 746 NVDIRQYSYSGQPDDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTVIEYSGSNNAV-- 803
Query: 285 PDKLRSLGPINEPLYLSLLLIDE--NVGVEYEYSLPIEKAPLPTQRYSW-VHGNFSSCSA 341
+++ S + + + +L + N V Y +++P+E+ + ++W +G + C+
Sbjct: 804 -ERINSTNRQEKEILIEVLCVGNLYNPDVHYSFNIPLEER---SDMFTWDPYGPWEGCTK 859
Query: 342 TCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACPPQWVPGNWSRCSKR 400
C G +Q R++TC + + VV + CD P+ Q+CNT C +W S CS +
Sbjct: 860 MCQG-LQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTD-CELRWHVIGKSECSSQ 917
Query: 401 CGKDGTRSREVRCEKI-ITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWK 459
CG+ G R+ ++ C K I G VDD C D L KP E C+ + W S W
Sbjct: 918 CGQ-GYRTLDIHCMKYSIHEGQTVQVDDHYCGDQL--KPPTQELCHGNCVFTRWHYSEWS 974
Query: 460 PCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWT 519
C + CG G+++R+ C R L+D+EC E + R+ C C W SEW+
Sbjct: 975 QCSRSCGGGERSRESYCMNNFGHR---LADNECQELSRVTRENCNEFSCPS--WAASEWS 1029
Query: 520 GC-DTCLATVRSRVAQC-VTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
C TC + R C + D+ ++ FC+ P PC+ L C W W
Sbjct: 1030 ECLVTCGKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPCE---LHTC-ASWQVGPW 1083
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK-----PCEVPEE---- 628
C+ CG G + R V C ++V+ +D+ C + + +D + PC +
Sbjct: 1084 GPCTTTCGHGYQMRDVKCVNELASAVL--EDTECHEASRPSDRQSCVLTPCSFISKLETA 1141
Query: 629 -------KCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
K ++W W+ C+ SCG+G + R V C
Sbjct: 1142 LLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC 1177
Score = 134 bits (325), Expect = 2e-30
Identities = 103/353 (29%), Positives = 153/353 (43%), Gaps = 36/353 (10%)
Query: 352 VTCRSREELEVVDEGLCDDGL-KPATNQTCNT----QACPPQWVP-GNWSRCSKRCGKDG 405
+ +R+E E++ E LC L P + + N ++ W P G W C+K C G
Sbjct: 806 INSTNRQEKEILIEVLCVGNLYNPDVHYSFNIPLEERSDMFTWDPYGPWEGCTKMC--QG 863
Query: 406 TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY-ESCNVDAACPTWFISPWKPCDKL 464
+ R + C I SVV DKEC L P P+ +SCN D W + C
Sbjct: 864 LQRRNITC---IHKSDHSVVSDKECDHL--PLPSFVTQSCNTDCEL-RWHVIGKSECSSQ 917
Query: 465 CGSGQQTRQVVC--YQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEGVDWMVSEWTGC 521
CG G +T + C Y + G+ + D C ++ KP ++ C C W SEW+ C
Sbjct: 918 CGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGN-CVFTRWHYSEWSQC 976
Query: 522 D-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKC 580
+C RSR + C+ + + C + E C++ P+ W A++WS+C
Sbjct: 977 SRSCGGGERSRESYCMNNFGHRLADNECQ-ELSRVTRENCNEFSCPS----WAASEWSEC 1031
Query: 581 SVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWS 640
V CG G K R+V+C +V + D C K PCE+ C S W PW
Sbjct: 1032 LVTCGKGTKQRQVWCQ----LNVDHLSDGFCNSSTKPESLSPCEL--HTCAS-WQVGPWG 1084
Query: 641 ECTKSCGKGLRFRSVVCLR----GGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
CT +CG G + R V C+ E ++C + S P SC C + +
Sbjct: 1085 PCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISK 1137
Score = 130 bits (315), Expect = 4e-29
Identities = 93/365 (25%), Positives = 150/365 (41%), Gaps = 24/365 (6%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP--Q 388
W +GN+ CS TCGGGI+SR V C+ +++++ C+ KP + C+ ACP
Sbjct: 1360 WNYGNWGECSQTCGGGIKSRLVICQFPNG-QILEDHNCEIVNKPPSVIQCHMHACPADVS 1418
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W W+ CS CGK G + REV C + ++D C + KP +++C
Sbjct: 1419 WHQEPWTSCSASCGK-GRKYREVFC----IDQFQRKLEDTNCSQV--QKPPTHKACR-SV 1470
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEP 507
CP+W + W C CGSG Q R V C K G++ ++ C + +P ++ C +
Sbjct: 1471 RCPSWKANSWNECSVTCGSGVQQRDVYCRLKGVGQV---VEEMCDQSTRPCSQRRCWSQD 1527
Query: 508 CEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLP 566
C M C T C + +C R VN + + C + P
Sbjct: 1528 CVQHKGMERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNC---RNP 1584
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVP 626
C S+C+ CG + R +C + K+ ++ +V
Sbjct: 1585 PCNYIVVTADSSQCANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVY 1644
Query: 627 E--EKC--PSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNE 681
+ C + W WS+C+ +CG G+ R V C+ + G C P + C
Sbjct: 1645 QCINSCLHLATWKVGKWSKCSVTCGIGIMKRQVKCITKHGLSSDLCLNHLKPGAQKKCYA 1704
Query: 682 QSCEA 686
C++
Sbjct: 1705 NDCKS 1709
Score = 126 bits (304), Expect = 9e-28
Identities = 104/376 (27%), Positives = 159/376 (42%), Gaps = 51/376 (13%)
Query: 319 IEKAPLPT----QRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP 374
+E A LPT + W HG+++ CS +CG G Q+R V+CR + + DE C +P
Sbjct: 1138 LETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALD-RIADESYCAHLPRP 1196
Query: 375 ATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLL 434
A C T +W G+WS CS CG G +R+V C +D+ C +
Sbjct: 1197 AEIWDCFTPC--GEWQAGDWSPCSASCGH-GKTTRQVLCMNY-----HQPIDENYCDPEV 1248
Query: 435 GPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE 494
+P + + C++ AACP P + S + + QK L D+E
Sbjct: 1249 --RPLMEQECSL-AACPP--AHSHFPSSPVQPSYYLSTNLPLTQK-------LEDNENQV 1296
Query: 495 EKPLDRQPCELEPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFCSYHPT 553
P R G W W C + C ++ R C +D ++S+C
Sbjct: 1297 VHPSVR---------GNQWRTGPWGQCSSSCSGGLQHRAVVC--QDENGQSASYCDAASK 1345
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
P + C P QW W +CS CG G K+R V C +F ++ +D NC
Sbjct: 1346 PPELQQCGPGPCP----QWNYGNWGECSQTCGGGIKSRLVIC-QFPNGQIL--EDHNCEI 1398
Query: 614 EEKYNDSKPCEVPEEKCPS--KWYAAPWSECTKSCGKGLRFRSVVCL---RGGKEFSDCP 668
K C + CP+ W+ PW+ C+ SCGKG ++R V C+ + E ++C
Sbjct: 1399 VNKPPSVIQCHM--HACPADVSWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNCS 1456
Query: 669 KKSLPDSAGSCNEQSC 684
+ P + +C C
Sbjct: 1457 QVQKPPTHKACRSVRC 1472
Score = 124 bits (299), Expect = 3e-27
Identities = 93/332 (28%), Positives = 134/332 (40%), Gaps = 29/332 (8%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W G + CS++C GG+Q R V C+ CD KP Q C C PQW
Sbjct: 1306 WRTGPWGQCSSSCSGGLQHRAVVCQDENGQSA---SYCDAASKPPELQQCGPGPC-PQWN 1361
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
GNW CS+ CG G +SR V C+ NG +++D C +++ P++ + C++ AC
Sbjct: 1362 YGNWGECSQTCG-GGIKSRLVICQ--FPNG--QILEDHNC-EIVNKPPSVIQ-CHMH-AC 1413
Query: 451 P---TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELE 506
P +W PW C CG G++ R+V C + + L D CS+ +KP + C
Sbjct: 1414 PADVSWHQEPWTSCSASCGKGRKYREVFCIDQFQRK---LEDTNCSQVQKPPTHKACRSV 1470
Query: 507 PCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
C W + W C TC + V+ R C K V C P + C
Sbjct: 1471 RCP--SWKANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEEMCDQSTRPCSQRRCWSQ-- 1526
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
Q + CS C +R+ C + +V++ SK C
Sbjct: 1527 DCVQHKGMERGRLNCSTSCERKDSHQRMEC---TDNQIRQVNEIVYNSSTISLTSKNCRN 1583
Query: 626 PEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
P C A S+C +CG R R C
Sbjct: 1584 P--PCNYIVVTADSSQCANNCGFSYRQRITYC 1613
Score = 107 bits (257), Expect = 4e-22
Identities = 95/383 (24%), Positives = 146/383 (38%), Gaps = 61/383 (15%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
SW +S C TCG G + R V C+ ++ + +G C+ KP + C C W
Sbjct: 1022 SWAASEWSECLVTCGKGTKQRQVWCQLN--VDHLSDGFCNSSTKPESLSPCELHTCA-SW 1078
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK--------PALY 441
G W C+ CG G + R+V+C + + +V++D EC + P P +
Sbjct: 1079 QVGPWGPCTTTCGH-GYQMRDVKCVNELAS---AVLEDTECHEASRPSDRQSCVLTPCSF 1134
Query: 442 ESCNVDAACPT--------WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS 493
S A PT W W PC CG G Q R V C + + + C+
Sbjct: 1135 ISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC---RDALDRIADESYCA 1191
Query: 494 E-EKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYH 551
+P + C PC +W +W+ C +C +R C+ +YH
Sbjct: 1192 HLPRPAEIWDC-FTPCG--EWQAGDWSPCSASCGHGKTTRQVLCM------------NYH 1236
Query: 552 PTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVD--DS 609
P E CD + P + +CS+ + F + V +
Sbjct: 1237 Q-PIDENYCDPEVRPLME--------QECSLAACPPAHSH------FPSSPVQPSYYLST 1281
Query: 610 NCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCP 668
N P +K D++ V ++W PW +C+ SC GL+ R+VVC G+ S C
Sbjct: 1282 NLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCSSSCSGGLQHRAVVCQDENGQSASYCD 1341
Query: 669 KKSLPDSAGSCNEQSCEALGEGS 691
S P C C G+
Sbjct: 1342 AASKPPELQQCGPGPCPQWNYGN 1364
Score = 101 bits (243), Expect = 2e-20
Identities = 76/257 (29%), Positives = 107/257 (41%), Gaps = 22/257 (8%)
Query: 372 LKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
L+ NQ + QW G W +CS C G + R V C+ NG + D
Sbjct: 1289 LEDNENQVVHPSVRGNQWRTGPWGQCSSSCS-GGLQHRAVVCQD--ENGQSASYCDA--- 1342
Query: 432 DLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDE 491
KP + C CP W W C + CG G ++R V+C Q NG+I L D
Sbjct: 1343 ---ASKPPELQQCG-PGPCPQWNYGNWGECSQTCGGGIKSRLVIC-QFPNGQI--LEDHN 1395
Query: 492 CS-EEKPLDRQPCELEPCEG-VDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
C KP C + C V W WT C +C + R C+ + R + + C
Sbjct: 1396 CEIVNKPPSVIQCHMHACPADVSWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNC 1455
Query: 549 SYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCG-KFDGASVMKV- 606
S P + C + P+ W A W++CSV CG G + R V+C K G V ++
Sbjct: 1456 SQVQKPPTHKACRSVRCPS----WKANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEEMC 1511
Query: 607 DDSNCPKEEKYNDSKPC 623
D S P ++ S+ C
Sbjct: 1512 DQSTRPCSQRRCWSQDC 1528
Score = 88.2 bits (209), Expect = 3e-16
Identities = 68/273 (24%), Positives = 110/273 (40%), Gaps = 18/273 (6%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
SW ++SCSA+CG G + R+V C + + ++ D C KP T++ C + C P W
Sbjct: 1418 SWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTN-CSQVQKPPTHKACRSVRC-PSW 1475
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC-NVDA 448
+W+ CS CG G + R+V C G+ VV++ C +P C + D
Sbjct: 1476 KANSWNECSVTCG-SGVQQRDVYCR---LKGVGQVVEEM-CDQ--STRPCSQRRCWSQDC 1528
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
C C +++ C ++N + + S L + C PC
Sbjct: 1529 VQHKGMERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYN--SSTISLTSKNCRNPPC 1586
Query: 509 EGVDWMVSEWTGCDTCLATVRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDK 564
+ + C + R R+ C TK +++ Y P +
Sbjct: 1587 NYIVVTADSSQCANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQC 1646
Query: 565 LPAC--QVQWYATQWSKCSVECGVGKKTRRVFC 595
+ +C W +WSKCSV CG+G R+V C
Sbjct: 1647 INSCLHLATWKVGKWSKCSVTCGIGIMKRQVKC 1679
Score = 73.7 bits (173), Expect = 6e-12
Identities = 61/251 (24%), Positives = 97/251 (38%), Gaps = 18/251 (7%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN 377
P KA + SW +++ CS TCG G+Q RDV CR + +VV+E +CD +P +
Sbjct: 1462 PTHKACRSVRCPSWKANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEE-MCDQSTRPCSQ 1520
Query: 378 QTCNTQAC-PPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP 436
+ C +Q C + + CS C + + R + C + +V + L
Sbjct: 1521 RRCWSQDCVQHKGMERGRLNCSTSCERKDSHQR-MECTDNQIRQVNEIVYNSSTISLTS- 1578
Query: 437 KPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQ----KNN--GRINVLSDD 490
K CN + C CG + R C + K + R+ +
Sbjct: 1579 KNCRNPPCNYIVV-----TADSSQCANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQ 1633
Query: 491 ECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCS 549
EC C W V +W+ C TC + R +C+TK ++S C
Sbjct: 1634 ECPVVPSSQVYQCINSCLHLATWKVGKWSKCSVTCGIGIMKRQVKCITK--HGLSSDLCL 1691
Query: 550 YHPTPALEEPC 560
H P ++ C
Sbjct: 1692 NHLKPGAQKKC 1702
Score = 36.3 bits (80), Expect = 1.2
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWS 395
+SSCS TCGGGI+S C E C + ++CNT +CP
Sbjct: 565 YSSCSRTCGGGIESATRRCNRPEPRN--GGNYCVG--RRMKFRSCNTDSCPKGTQDFREK 620
Query: 396 RCSKRCGK 403
+CS GK
Sbjct: 621 QCSDFNGK 628
>AB209515-1|BAD92752.1| 847|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 847
Score = 301 bits (739), Expect = 2e-80
Identities = 152/404 (37%), Positives = 215/404 (53%), Gaps = 12/404 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV+S R C P G C G ++ SC T DCP S DFR QC+++++
Sbjct: 313 CSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCPPGSQDFREVQCSEFDS 372
Query: 117 VTFRGKKYRWVPYLKVS-KPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQ 175
+ FRGK Y+W Y K C LTC+ G FY V+DGT C D+ D+CV G C+
Sbjct: 373 IPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECK 432
Query: 176 PVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITE 235
VGCD +LGS+ +EDKCR C G+G C T + + + GY D++ IP+G+ I+I +
Sbjct: 433 HVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQD 492
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPIN 295
+ S ++LAL+ + L G P + +AG + +QG L +LGPIN
Sbjct: 493 LNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQL---RQGPDQVQSLEALGPIN 549
Query: 296 EPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCR 355
L + +L E + Y ++ PI + LP YSW + ++ CSA C GG Q + V CR
Sbjct: 550 ASLIVMVLARTELPALRYRFNAPIARDSLPP--YSWHYAPWTKCSAQCAGGSQVQAVECR 607
Query: 356 SREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCE 414
++ + V C K P + CNT+ CPP WV GNWS CS+ C G RSR V C+
Sbjct: 608 NQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDA-GVRSRSVVCQ 666
Query: 415 KIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPW 458
+ ++ +DD C P+P + E+C+ P W W
Sbjct: 667 RRVSAAEEKALDDSACPQ---PRPPVLEACHGPTCPPEWAALDW 707
Score = 89.4 bits (212), Expect = 1e-16
Identities = 70/280 (25%), Positives = 110/280 (39%), Gaps = 34/280 (12%)
Query: 386 PPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCN 445
P W W++CS +C G++ + V C + + S V C P +CN
Sbjct: 580 PYSWHYAPWTKCSAQCA-GGSQVQAVECRNQLDS---SAVAPHYC-SAHSKLPKRQRACN 634
Query: 446 VDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQK-NNGRINVLSDDECSEEKPLDRQPCE 504
+ P W + W C + C +G ++R VVC ++ + L D C + +P + C
Sbjct: 635 TEPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACH 694
Query: 505 LEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDK 564
C +W +W+ L SR C + P L+ C
Sbjct: 695 GPTCP-PEWAALDWSEVSRPLP---SRPLGC--------PGGVSTETPLRGLQVSC---- 738
Query: 565 LPACQVQWYATQWSK------CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYN 618
P W +T +K C+ CG G + R V C D + + ++C K
Sbjct: 739 -PLLTSHWGSTLSTKRPFQLQCTPSCGPGLRHRVVLCKSADHRATL--PPAHCSPAAKPP 795
Query: 619 DSKPCEVPEEKC-PSKWYAAPWSECTKSCGKGLRFRSVVC 657
+ C + +C P++W A W EC+ CG G R RSV C
Sbjct: 796 ATMRCNL--RRCPPARWVAGEWGECSAQCGVGQRQRSVRC 833
Score = 73.7 bits (173), Expect = 6e-12
Identities = 57/212 (26%), Positives = 82/212 (38%), Gaps = 23/212 (10%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSR---EELEVVDEGLCDDGLKPATNQTCNTQACPP 387
WV GN+S CS +C G++SR V C+ R E + +D+ C +P + C+ CPP
Sbjct: 642 WVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQP-RPPVLEACHGPTCPP 700
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVD 447
+W +WS S+ SR + C ++ P C P + +
Sbjct: 701 EWAALDWSEVSR-----PLPSRPLGCPGGVSTETPLRGLQVSC-----PLLTSHWGSTLS 750
Query: 448 AACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPCELE 506
P C CG G + R V+C K+ L CS KP C L
Sbjct: 751 TKRPFQL-----QCTPSCGPGLRHRVVLC--KSADHRATLPPAHCSPAAKPPATMRCNLR 803
Query: 507 PCEGVDWMVSEWTGCDT-CLATVRSRVAQCVT 537
C W+ EW C C R R +C +
Sbjct: 804 RCPPARWVAGEWGECSAQCGVGQRQRSVRCTS 835
Score = 68.1 bits (159), Expect = 3e-10
Identities = 42/119 (35%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query: 559 PCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC-GKFDGASVMKVDDSNCPKEEKY 617
P +D LP W+ W+KCS +C G + + V C + D ++V S K K
Sbjct: 572 PIARDSLPP--YSWHYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKR 629
Query: 618 NDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSA 676
+ C E CP W WS C++SC G+R RSVVC R S +K+L DSA
Sbjct: 630 Q--RACNT--EPCPPDWVVGNWSLCSRSCDAGVRSRSVVCQR---RVSAAEEKALDDSA 681
Score = 49.6 bits (113), Expect = 1e-04
Identities = 25/79 (31%), Positives = 39/79 (49%), Gaps = 3/79 (3%)
Query: 523 TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCS 581
+C +R RV C + D+R + + CS P C+ + P + W A +W +CS
Sbjct: 762 SCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPAR--WVAGEWGECS 819
Query: 582 VECGVGKKTRRVFCGKFDG 600
+CGVG++ R V C G
Sbjct: 820 AQCGVGQRQRSVRCTSHTG 838
>AF488804-1|AAO15766.1| 1911|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motifs 20
protein.
Length = 1911
Score = 295 bits (725), Expect = 8e-79
Identities = 191/636 (30%), Positives = 299/636 (47%), Gaps = 59/636 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN- 115
CSRTCGGG+ S R C P NG C G K+ SC T CP+ + DFR +QC+ +N
Sbjct: 568 CSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNG 627
Query: 116 ---NVTFRGKKYRWVPY---LKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
+++ RW+P + C+L C G ++Y K+ V DGT C ++ D+C
Sbjct: 628 KHLDISGIPSNVRWLPRYSGIGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTETHDIC 687
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGAT 229
V G C GCD +L S+AK DKC C G+ +C T + N+ GYN ++ IP GAT
Sbjct: 688 VQGQCMAAGCDHVLNSSAKIDKCGVCGGDNSSCKTITGVFNSSHY--GYNVVVKIPAGAT 745
Query: 230 TIYITEI----EPSNNYLALRSKNGTYYLNGDYHIDFPRS-MTIAGALWNYERNQQGITA 284
+ I + +P ++YLAL G + NG++ + + + + G E + A
Sbjct: 746 NVDIRQYSYSGQPDDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTRTVIEYSGSN-NA 804
Query: 285 PDKLRSLGPINEPLYLSLLLIDE--NVGVEYEYSLPIEKAPLPTQRYSW-VHGNFSSCSA 341
+++ S + L L +L + N V Y +++P+E+ + ++W +G + C+
Sbjct: 805 VERINSTNRQEKELILQVLCVGNLYNPDVHYSFNIPLEER---SDMFTWDPYGPWEGCTK 861
Query: 342 TCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACPPQWVPGNWSRCSKR 400
C G +Q R++TC + + VV + CD P+ Q+CNT + S CS +
Sbjct: 862 MCQG-LQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTDCELRGMLLAKKSECSSQ 920
Query: 401 CGKDGTRSREVRCEKI-ITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWK 459
CG+ G R+ ++ C K I G VDD C D L KP E C+ + W S W
Sbjct: 921 CGQ-GYRTLDIHCMKYSIHEGQTVQVDDHYCGDQL--KPPTQELCHGNCVFTRWHYSEWS 977
Query: 460 PCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWT 519
C + CG G+++R+ C R L+D+EC E + R+ C C W SEW+
Sbjct: 978 QCSRSCGGGERSRESYCMNNFGHR---LADNECQELSRVTRENCNEFSCPS--WAASEWS 1032
Query: 520 GC-DTCLATVRSRVAQC-VTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
C TC + R C + D+ ++ FC+ P PC+ L C W W
Sbjct: 1033 ECLVTCGKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPCE---LHTC-ASWQVGPW 1086
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK-----PCEVPEE---- 628
C+ CG G + R V C ++V+ +D+ C + + +D + PC +
Sbjct: 1087 GPCTTTCGHGYQMRDVKCVNELASAVL--EDTECHEASRPSDRQSCVLTPCSFISKLETA 1144
Query: 629 -------KCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
K ++W W+ C+ SCG+G + R V C
Sbjct: 1145 LLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC 1180
Score = 133 bits (321), Expect = 7e-30
Identities = 101/353 (28%), Positives = 153/353 (43%), Gaps = 35/353 (9%)
Query: 352 VTCRSREELEVVDEGLCDDGL-KPATNQTCNT----QACPPQWVP-GNWSRCSKRCGKDG 405
+ +R+E E++ + LC L P + + N ++ W P G W C+K C G
Sbjct: 808 INSTNRQEKELILQVLCVGNLYNPDVHYSFNIPLEERSDMFTWDPYGPWEGCTKMC--QG 865
Query: 406 TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY-ESCNVDAACPTWFISPWKPCDKL 464
+ R + C I SVV DKEC L P P+ +SCN D ++ C
Sbjct: 866 LQRRNITC---IHKSDHSVVSDKECDHL--PLPSFVTQSCNTDCELRGMLLAKKSECSSQ 920
Query: 465 CGSGQQTRQVVC--YQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEGVDWMVSEWTGC 521
CG G +T + C Y + G+ + D C ++ KP ++ C C W SEW+ C
Sbjct: 921 CGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGN-CVFTRWHYSEWSQC 979
Query: 522 D-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKC 580
+C RSR + C+ + + C + E C++ P+ W A++WS+C
Sbjct: 980 SRSCGGGERSRESYCMNNFGHRLADNECQ-ELSRVTRENCNEFSCPS----WAASEWSEC 1034
Query: 581 SVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWS 640
V CG G K R+V+C +V + D C K PCE+ C S W PW
Sbjct: 1035 LVTCGKGTKQRQVWCQ----LNVDHLSDGFCNSSTKPESLSPCEL--HTCAS-WQVGPWG 1087
Query: 641 ECTKSCGKGLRFRSVVCLR----GGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
CT +CG G + R V C+ E ++C + S P SC C + +
Sbjct: 1088 PCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISK 1140
Score = 130 bits (315), Expect = 4e-29
Identities = 93/365 (25%), Positives = 150/365 (41%), Gaps = 24/365 (6%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP--Q 388
W +GN+ CS TCGGGI+SR V C+ +++++ C+ KP + C+ ACP
Sbjct: 1363 WNYGNWGECSQTCGGGIKSRLVICQFPNG-QILEDHNCEIVNKPPSVIQCHMHACPADVS 1421
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W W+ CS CGK G + REV C + ++D C + KP +++C
Sbjct: 1422 WHQEPWTSCSASCGK-GRKYREVFC----IDQFQRKLEDTNCSQV--QKPPTHKACR-SV 1473
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEP 507
CP+W + W C CGSG Q R V C K G++ ++ C + +P ++ C +
Sbjct: 1474 RCPSWKANSWNECSVTCGSGVQQRDVYCRLKGVGQV---VEEMCDQSTRPCSQRRCWSQD 1530
Query: 508 CEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLP 566
C M C T C + +C R VN + + C + P
Sbjct: 1531 CVQHKGMERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYNSSTISLTSKNC---RNP 1587
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVP 626
C S+C+ CG + R +C + K+ ++ +V
Sbjct: 1588 PCNYIVVTADSSQCANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVY 1647
Query: 627 E--EKC--PSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNE 681
+ C + W WS+C+ +CG G+ R V C+ + G C P + C
Sbjct: 1648 QCINSCLHLATWKVGKWSKCSVTCGIGIMKRQVKCITKHGLSSDLCLNHLKPGAQKKCYA 1707
Query: 682 QSCEA 686
C++
Sbjct: 1708 NDCKS 1712
Score = 124 bits (300), Expect = 3e-27
Identities = 103/376 (27%), Positives = 158/376 (42%), Gaps = 51/376 (13%)
Query: 319 IEKAPLPT----QRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP 374
+E A LPT + W HG+++ CS +CG G Q+R V+CR + + DE C +P
Sbjct: 1141 LETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALD-RIADESYCAHLPRP 1199
Query: 375 ATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLL 434
A C T +W G+WS CS CG G +R+V C +D+ C +
Sbjct: 1200 AEIWDCFTPC--GEWQAGDWSPCSASCGH-GKTTRQVLCMNY-----HQPIDENYCDPEV 1251
Query: 435 GPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE 494
+P + + C++ AACP P + S + + QK L D+E
Sbjct: 1252 --RPLMEQECSL-AACPP--AHSHFPSSPVQPSYYLSTNLPLTQK-------LEDNENQV 1299
Query: 495 EKPLDRQPCELEPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFCSYHPT 553
P R G W W C + C ++ C +D ++S+C
Sbjct: 1300 VHPSVR---------GNQWRTGPWGSCSSSCSGGLQHTAVVC--QDENGQSASYCDAASK 1348
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
P + C P QW W +CS CG G K+R V C +F ++ +D NC
Sbjct: 1349 PPELQQCGPGPCP----QWNYGNWGECSQTCGGGIKSRLVIC-QFPNGQIL--EDHNCEI 1401
Query: 614 EEKYNDSKPCEVPEEKCPS--KWYAAPWSECTKSCGKGLRFRSVVCL---RGGKEFSDCP 668
K C + CP+ W+ PW+ C+ SCGKG ++R V C+ + E ++C
Sbjct: 1402 VNKPPSVIQCHM--HACPADVSWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNCS 1459
Query: 669 KKSLPDSAGSCNEQSC 684
+ P + +C C
Sbjct: 1460 QVQKPPTHKACRSVRC 1475
Score = 123 bits (297), Expect = 6e-27
Identities = 93/332 (28%), Positives = 134/332 (40%), Gaps = 29/332 (8%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W G + SCS++C GG+Q V C+ CD KP Q C C PQW
Sbjct: 1309 WRTGPWGSCSSSCSGGLQHTAVVCQDENGQSA---SYCDAASKPPELQQCGPGPC-PQWN 1364
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
GNW CS+ CG G +SR V C+ NG +++D C +++ P++ + C++ AC
Sbjct: 1365 YGNWGECSQTCG-GGIKSRLVICQ--FPNG--QILEDHNC-EIVNKPPSVIQ-CHMH-AC 1416
Query: 451 P---TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELE 506
P +W PW C CG G++ R+V C + + L D CS+ +KP + C
Sbjct: 1417 PADVSWHQEPWTSCSASCGKGRKYREVFCIDQFQRK---LEDTNCSQVQKPPTHKACRSV 1473
Query: 507 PCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
C W + W C TC + V+ R C K V C P + C
Sbjct: 1474 RCP--SWKANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEEMCDQSTRPCSQRRCWSQ-- 1529
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
Q + CS C +R+ C + +V++ SK C
Sbjct: 1530 DCVQHKGMERGRLNCSTSCERKDSHQRMEC---TDNQIRQVNEIVYNSSTISLTSKNCRN 1586
Query: 626 PEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
P C A S+C +CG R R C
Sbjct: 1587 P--PCNYIVVTADSSQCANNCGFSYRQRITYC 1616
Score = 104 bits (249), Expect = 4e-21
Identities = 94/383 (24%), Positives = 144/383 (37%), Gaps = 61/383 (15%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
SW +S C TCG G + R V C+ ++ + +G C+ KP + C C W
Sbjct: 1025 SWAASEWSECLVTCGKGTKQRQVWCQLN--VDHLSDGFCNSSTKPESLSPCELHTCA-SW 1081
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK--------PALY 441
G W C+ CG G + R+V+C + + +V++D EC + P P +
Sbjct: 1082 QVGPWGPCTTTCGH-GYQMRDVKCVNELAS---AVLEDTECHEASRPSDRQSCVLTPCSF 1137
Query: 442 ESCNVDAACPT--------WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS 493
S A PT W W PC CG G Q R V C + + + C+
Sbjct: 1138 ISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC---RDALDRIADESYCA 1194
Query: 494 E-EKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYH 551
+P + C PC +W +W+ C +C +R C+ +YH
Sbjct: 1195 HLPRPAEIWDC-FTPCG--EWQAGDWSPCSASCGHGKTTRQVLCM------------NYH 1239
Query: 552 PTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVD--DS 609
P E CD + P + +CS+ + F + V +
Sbjct: 1240 Q-PIDENYCDPEVRPLME--------QECSLAACPPAHSH------FPSSPVQPSYYLST 1284
Query: 610 NCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCP 668
N P +K D++ V ++W PW C+ SC GL+ +VVC G+ S C
Sbjct: 1285 NLPLTQKLEDNENQVVHPSVRGNQWRTGPWGSCSSSCSGGLQHTAVVCQDENGQSASYCD 1344
Query: 669 KKSLPDSAGSCNEQSCEALGEGS 691
S P C C G+
Sbjct: 1345 AASKPPELQQCGPGPCPQWNYGN 1367
Score = 98.7 bits (235), Expect = 2e-19
Identities = 75/257 (29%), Positives = 105/257 (40%), Gaps = 22/257 (8%)
Query: 372 LKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
L+ NQ + QW G W CS C G + V C+ NG + D
Sbjct: 1292 LEDNENQVVHPSVRGNQWRTGPWGSCSSSCS-GGLQHTAVVCQD--ENGQSASYCDA--- 1345
Query: 432 DLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDE 491
KP + C CP W W C + CG G ++R V+C Q NG+I L D
Sbjct: 1346 ---ASKPPELQQCG-PGPCPQWNYGNWGECSQTCGGGIKSRLVIC-QFPNGQI--LEDHN 1398
Query: 492 CS-EEKPLDRQPCELEPCEG-VDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
C KP C + C V W WT C +C + R C+ + R + + C
Sbjct: 1399 CEIVNKPPSVIQCHMHACPADVSWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTNC 1458
Query: 549 SYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCG-KFDGASVMKV- 606
S P + C + P+ W A W++CSV CG G + R V+C K G V ++
Sbjct: 1459 SQVQKPPTHKACRSVRCPS----WKANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEEMC 1514
Query: 607 DDSNCPKEEKYNDSKPC 623
D S P ++ S+ C
Sbjct: 1515 DQSTRPCSQRRCWSQDC 1531
Score = 88.2 bits (209), Expect = 3e-16
Identities = 68/273 (24%), Positives = 110/273 (40%), Gaps = 18/273 (6%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
SW ++SCSA+CG G + R+V C + + ++ D C KP T++ C + C P W
Sbjct: 1421 SWHQEPWTSCSASCGKGRKYREVFCIDQFQRKLEDTN-CSQVQKPPTHKACRSVRC-PSW 1478
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC-NVDA 448
+W+ CS CG G + R+V C G+ VV++ C +P C + D
Sbjct: 1479 KANSWNECSVTCG-SGVQQRDVYCR---LKGVGQVVEEM-CDQ--STRPCSQRRCWSQDC 1531
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
C C +++ C ++N + + S L + C PC
Sbjct: 1532 VQHKGMERGRLNCSTSCERKDSHQRMECTDNQIRQVNEIVYN--SSTISLTSKNCRNPPC 1589
Query: 509 EGVDWMVSEWTGCDTCLATVRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDK 564
+ + C + R R+ C TK +++ Y P +
Sbjct: 1590 NYIVVTADSSQCANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQECPVVPSSQVYQC 1649
Query: 565 LPAC--QVQWYATQWSKCSVECGVGKKTRRVFC 595
+ +C W +WSKCSV CG+G R+V C
Sbjct: 1650 INSCLHLATWKVGKWSKCSVTCGIGIMKRQVKC 1682
Score = 73.7 bits (173), Expect = 6e-12
Identities = 61/251 (24%), Positives = 97/251 (38%), Gaps = 18/251 (7%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN 377
P KA + SW +++ CS TCG G+Q RDV CR + +VV+E +CD +P +
Sbjct: 1465 PTHKACRSVRCPSWKANSWNECSVTCGSGVQQRDVYCRLKGVGQVVEE-MCDQSTRPCSQ 1523
Query: 378 QTCNTQAC-PPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP 436
+ C +Q C + + CS C + + R + C + +V + L
Sbjct: 1524 RRCWSQDCVQHKGMERGRLNCSTSCERKDSHQR-MECTDNQIRQVNEIVYNSSTISLTS- 1581
Query: 437 KPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQ----KNN--GRINVLSDD 490
K CN + C CG + R C + K + R+ +
Sbjct: 1582 KNCRNPPCNYIVV-----TADSSQCANNCGFSYRQRITYCTEIPSTKKHKLHRLRPIVYQ 1636
Query: 491 ECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCS 549
EC C W V +W+ C TC + R +C+TK ++S C
Sbjct: 1637 ECPVVPSSQVYQCINSCLHLATWKVGKWSKCSVTCGIGIMKRQVKCITK--HGLSSDLCL 1694
Query: 550 YHPTPALEEPC 560
H P ++ C
Sbjct: 1695 NHLKPGAQKKC 1705
Score = 36.3 bits (80), Expect = 1.2
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWS 395
+SSCS TCGGGI+S C E C + ++CNT +CP
Sbjct: 565 YSSCSRTCGGGIESATRRCNRPEPRN--GGNYCVG--RRMKFRSCNTDSCPKGTQDFREK 620
Query: 396 RCSKRCGK 403
+CS GK
Sbjct: 621 QCSDFNGK 628
>AY327122-1|AAQ94616.1| 1686|Homo sapiens COMPase precursor protein.
Length = 1686
Score = 291 bits (714), Expect = 2e-77
Identities = 154/430 (35%), Positives = 223/430 (51%), Gaps = 21/430 (4%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQ-CTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CG GV S +R C + P + + C G ++ C Q CP FR QC+ ++
Sbjct: 550 CSRSCGMGVQSAERQCTQPTPKYKGRYCVGERKRFRLCNLQACPAGXPSFRHVQCSHFDA 609
Query: 117 VTFRGKKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCND--DSFDVCVDGVC 174
+ ++G+ + WVP + PCEL C + F + ++ V+DGT C S D+C++G+C
Sbjct: 610 MLYKGQLHTWVPVVNDVNPCELHCRPANEYFAEKLRDAVVDGTPCYQVRASRDLCINGIC 669
Query: 175 QPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYIT 234
+ VGCD + S A ED+C C GNG CHT + GY D+ LIP GA I I
Sbjct: 670 KNVGCDFEIDSGAMEDRCGVCHGNGSTCHTVSGTFEEAE-GLGYVDVGLIPAGAREIRIQ 728
Query: 235 EIEPSNNYLALRSKNGT-YYLNGDYHIDFPRSMTIAGALWNYER--NQQGITAPDKLRSL 291
E+ + N+LALRS++ Y+LNG + I + +AG + Y R N + +T+P
Sbjct: 729 EVAEAANFLALRSEDPEKYFLNGGWTIQWNGDYQVAGTTFTYARRGNWENLTSP------ 782
Query: 292 GPINEPLYLSLLLIDENVGVEYEYSLPIEKA---PLPTQRYSWVHGNFSSCSATCGGGIQ 348
GP EP+++ LL + N GV YEY++ E +P +SW +G ++ C+ TCG G+Q
Sbjct: 783 GPTKEPVWIQLLFQESNPGVHYEYTIHREAGGHDEVPPPVFSWHYGPWTKCTVTCGRGVQ 842
Query: 349 SRDVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTR 407
++V C R + VDE CD +P Q C+ Q CP +W G W CS CG G
Sbjct: 843 RQNVYCLER-QAGPVDEEHCDPLGRPDDQQRKCSEQPCPARWWAGEWQLCSSSCGPGGLS 901
Query: 408 SREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP-TWFISPWKPCDKLCG 466
R V C + + S ++ C L P+P CN CP TW + W C CG
Sbjct: 902 RRAVLCIRSVGLDEQSALEPPACEHL--PRPPTETPCNRHVPCPATWAVGNWSQCSVTCG 959
Query: 467 SGQQTRQVVC 476
G Q R V+C
Sbjct: 960 EGTQRRNVLC 969
Score = 108 bits (259), Expect = 2e-22
Identities = 73/243 (30%), Positives = 105/243 (43%), Gaps = 31/243 (12%)
Query: 323 PLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNT 382
PL + SW GN+S CS TCG G R V C S + + G +P + C+
Sbjct: 1407 PLVVRNASWQAGNWSECSTTCGLGAVWRPVRCSSGRDEDCAPAG------RPQPARRCHL 1460
Query: 383 QACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP-KPALY 441
+ C W GNWS+CS+ C G+ R+V+C + T L + + GP KP +
Sbjct: 1461 RPC-ATWHSGNWSKCSRSC-DGGSSVRDVQC--VDTRDLRPL---RPFHCQPGPAKPHAH 1513
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
C C +W+ S W+ C + CG G+Q R V C + C E +P
Sbjct: 1514 RPCGAQ-PCLSWYTSSWRECSEACGGGEQQRLVTCPEPG----------LCEEALRPNTT 1562
Query: 501 QPCELEPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRV--VNSSFCSYHPTPALE 557
+PC PC W+V W C C V+ R+ +CV + +S C + P
Sbjct: 1563 RPCNTHPC--TQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTGLPEEDSDQCGHEAWPESS 1620
Query: 558 EPC 560
PC
Sbjct: 1621 RPC 1623
Score = 100 bits (239), Expect = 6e-20
Identities = 70/243 (28%), Positives = 105/243 (43%), Gaps = 36/243 (14%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEG 510
+W W C CG G R V C ++GR D++C+ +P + C L PC
Sbjct: 1414 SWQAGNWSECSTTCGLGAVWRPVRC---SSGR-----DEDCAPAGRPQPARRCHLRPC-- 1463
Query: 511 VDWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFCSYHPT-PALEEPCDKDKLPA 567
W W+ C +C R QCV T+D R + C P P PC
Sbjct: 1464 ATWHSGNWSKCSRSCDGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPHAHRPCGAQP--- 1520
Query: 568 CQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPE 627
C + WY + W +CS CG G++ R V C + C + + N ++PC
Sbjct: 1521 C-LSWYTSSWRECSEACGGGEQQRLVTCP----------EPGLCEEALRPNTTRPCNT-- 1567
Query: 628 EKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG----GKEFSD-CPKKSLPDSAGSCNEQ 682
C ++W PW +C+ CG G++ R V C+ +E SD C ++ P+S+ C +
Sbjct: 1568 HPC-TQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTGLPEEDSDQCGHEAWPESSRPCGTE 1626
Query: 683 SCE 685
CE
Sbjct: 1627 DCE 1629
Score = 97.1 bits (231), Expect = 6e-19
Identities = 60/185 (32%), Positives = 78/185 (42%), Gaps = 19/185 (10%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDG-LKPATNQTCNTQACPPQ 388
+W GN+S CS +C GG RDV C +L + C G KP ++ C Q C
Sbjct: 1465 TWHSGNWSKCSRSCDGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPHAHRPCGAQPCL-S 1523
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W +W CS+ CG G + R V C + P + C + L P CN
Sbjct: 1524 WYTSSWRECSEACG-GGEQQRLVTCPE------PGL-----CEEALRPNTT--RPCNTHP 1569
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK-PLDRQPCELEP 507
C W + PW C CG G Q R V C G + D+C E P +PC E
Sbjct: 1570 -CTQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTG-LPEEDSDQCGHEAWPESSRPCGTED 1627
Query: 508 CEGVD 512
CE V+
Sbjct: 1628 CEPVE 1632
Score = 81.4 bits (192), Expect = 3e-14
Identities = 48/172 (27%), Positives = 73/172 (42%), Gaps = 17/172 (9%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQ-PCELEPCE 509
+W PW C CG G Q + V C ++ G ++ ++ C +P D+Q C +PC
Sbjct: 824 SWHYGPWTKCTVTCGRGVQRQNVYCLERQAGPVD---EEHCDPLGRPDDQQRKCSEQPCP 880
Query: 510 GVDWMVSEWTGCDTCLAT--VRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKD 563
W EW C + + R C+ + + C + P P E PC++
Sbjct: 881 -ARWWAGEWQLCSSSCGPGGLSRRAVLCIRSVGLDEQSALEPPACEHLPRPPTETPCNR- 938
Query: 564 KLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEE 615
+P C W WS+CSV CG G + R V C G + D++ P E
Sbjct: 939 HVP-CPATWAVGNWSQCSVTCGEGTQRRNVLCTNDTG---VPCDEAQQPASE 986
Score = 74.9 bits (176), Expect = 3e-12
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W WT C TC V+ + C+ + V+ C P ++ K C +
Sbjct: 825 WHYGPWTKCTVTCGRGVQRQNVYCLERQAGPVDEEHCD--PLGRPDDQQRKCSEQPCPAR 882
Query: 572 WYATQWSKCSVECGVGKKTRR-VFCGKFDGASVMK-VDDSNCPKEEKYNDSKPCEVPEEK 629
W+A +W CS CG G +RR V C + G ++ C + PC
Sbjct: 883 WWAGEWQLCSSSCGPGGLSRRAVLCIRSVGLDEQSALEPPACEHLPRPPTETPCN-RHVP 941
Query: 630 CPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCE---- 685
CP+ W WS+C+ +CG+G + R+V+C C + P S +C+ C
Sbjct: 942 CPATWAVGNWSQCSVTCGEGTQRRNVLCT--NDTGVPCDEAQQPASEVTCSLPLCRWPLG 999
Query: 686 ALG-EGSG 692
LG EGSG
Sbjct: 1000 TLGPEGSG 1007
Score = 70.1 bits (164), Expect = 8e-11
Identities = 32/98 (32%), Positives = 55/98 (56%), Gaps = 5/98 (5%)
Query: 563 DKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP 622
D++P W+ W+KC+V CG G + + V+C + VD+ +C + +D +
Sbjct: 816 DEVPPPVFSWHYGPWTKCTVTCGRGVQRQNVYCLERQAG---PVDEEHCDPLGRPDDQQR 872
Query: 623 CEVPEEKCPSKWYAAPWSECTKSCGK-GLRFRSVVCLR 659
+ E+ CP++W+A W C+ SCG GL R+V+C+R
Sbjct: 873 -KCSEQPCPARWWAGEWQLCSSSCGPGGLSRRAVLCIR 909
Score = 55.2 bits (127), Expect = 2e-06
Identities = 37/127 (29%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 563 DKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP 622
D L W A WS+CS CG+G R V C G D +C + ++
Sbjct: 1406 DPLVVRNASWQAGNWSECSTTCGLGAVWRPVRCS--SGR------DEDCAPAGRPQPARR 1457
Query: 623 CEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPDSAG 677
C + C + W++ WS+C++SC G R V C LR + F P + P +
Sbjct: 1458 CHL--RPC-ATWHSGNWSKCSRSCDGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPHAHR 1514
Query: 678 SCNEQSC 684
C Q C
Sbjct: 1515 PCGAQPC 1521
Score = 48.0 bits (109), Expect = 4e-04
Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 8/57 (14%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGL-CDDGLKPATNQTCNTQAC 385
+W GN+S CS TCG G Q R+V C + D G+ CD+ +PA+ TC+ C
Sbjct: 945 TWAVGNWSQCSVTCGEGTQRRNVLCTN-------DTGVPCDEAQQPASEVTCSLPLC 994
Score = 44.4 bits (100), Expect = 0.004
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+ W A WSEC+ +CG G +R V C G E DC P A C+ + C G+
Sbjct: 1413 ASWQAGNWSECSTTCGLGAVWRPVRCSSGRDE--DCAPAGRPQPARRCHLRPCATWHSGN 1470
Score = 33.9 bits (74), Expect = 6.3
Identities = 20/50 (40%), Positives = 22/50 (44%), Gaps = 5/50 (10%)
Query: 56 TPCSRTCGGGVASQKRICLE--IGPNGEPQCT---GGDTKYFSCETQDCP 100
T C+ TCG GV Q CLE GP E C D + C Q CP
Sbjct: 831 TKCTVTCGRGVQRQNVYCLERQAGPVDEEHCDPLGRPDDQQRKCSEQPCP 880
>AJ515154-1|CAD56160.2| 1502|Homo sapiens ADAMTS-20 protein protein.
Length = 1502
Score = 291 bits (714), Expect = 2e-77
Identities = 189/636 (29%), Positives = 303/636 (47%), Gaps = 62/636 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN- 115
CSRTCGGG+ S R C P NG C G K+ SC T CP+ + DFR +QC+ +N
Sbjct: 568 CSRTCGGGIESATRRCNRPEPRNGGNYCVGRRMKFRSCNTDSCPKGTQDFREKQCSDFNG 627
Query: 116 ---NVTFRGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
+++ RW+P Y V C+L C G ++Y K+ V DGT C +S+++
Sbjct: 628 KHLDISGIPSNVRWLPRYSGVGTKDRCKLYCQVAGTNYFYLLKDMVEDGTPCGTESYNID 687
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGAT 229
+ V + GCD +L S+AK DKC C G+ +C T + N+ GYN ++ IP GAT
Sbjct: 688 CNCVLKAAGCDHVLNSSAKIDKCGVCGGDNSSCKTITGVFNSSHY--GYNVVVKIPAGAT 745
Query: 230 TIYITEI----EPSNNYLALRSKNGTYYLNGDYHIDFPRS-MTIAGALWNYERNQQGITA 284
+ I + +P ++YLAL G + NG++ + + + + G + Y + +
Sbjct: 746 NVDIRQYSYSGQPDDSYLALSDAEGNFLFNGNFLLSTSKKEINVQGTVIEYSGSNNAV-- 803
Query: 285 PDKLRSLGPINEPLYLSLLLIDE--NVGVEYEYSLPIEKAPLPTQRYSW-VHGNFSSCSA 341
+++ S + + + +L + N V Y +++P+E+ + ++W +G + C+
Sbjct: 804 -ERINSTNRQEKEILIEVLCVGNLYNPDVHYSFNIPLEER---SDMFTWDPYGPWEGCTK 859
Query: 342 TCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACPPQWVPGNWSRCSKR 400
C G +Q R++TC + + VV + CD P+ Q+CNT C +W S CS +
Sbjct: 860 MCQG-LQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTD-CELRWHVIGKSECSSQ 917
Query: 401 CGKDGTRSREVRCEKI-ITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWK 459
CG+ G R+ ++ C K I G VDD C D L KP E C+ + W S W
Sbjct: 918 CGQ-GYRTLDIHCMKYSIHEGQTVQVDDHYCGDQL--KPPTQELCHGNCVFTRWHYSEWS 974
Query: 460 PCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWT 519
C + CG G+++R+ C R L+D+EC E + R+ C C W SEW+
Sbjct: 975 QCSRSCGGGERSRESYCMNNFGHR---LADNECQELSRVTRENCNEFSCPS--WAASEWS 1029
Query: 520 GC-DTCLATVRSRVAQC-VTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
C TC + R C + D+ ++ FC+ P PC+ L C W W
Sbjct: 1030 ECLVTCGKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPCE---LHTC-ASWQVGPW 1083
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK-----PCEVPEE---- 628
C+ CG G + R V C ++V+ +D+ C + + +D + PC +
Sbjct: 1084 GPCTTTCGHGYQMRDVKCVNELASAVL--EDTECHEASRPSDRQSCVLTPCSFISKLETA 1141
Query: 629 -------KCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
K ++W W+ C+ SCG+G + R V C
Sbjct: 1142 LLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC 1177
Score = 152 bits (369), Expect = 1e-35
Identities = 116/372 (31%), Positives = 158/372 (42%), Gaps = 46/372 (12%)
Query: 337 SSCSATCGGGIQSRDVTCRSREELE----VVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
S CS+ CG G ++ D+ C E VD+ C D LKP T + C+ +W
Sbjct: 912 SECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGNCVFTRWHYS 971
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
WS+CS+ CG G RSRE C N + D EC +L E+CN + +CP+
Sbjct: 972 EWSQCSRSCG-GGERSRESYC----MNNFGHRLADNECQEL---SRVTRENCN-EFSCPS 1022
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC-SEEKPLDRQPCELEPCEGV 511
W S W C CG G + RQV C Q N ++ LSD C S KP PCEL C
Sbjct: 1023 WAASEWSECLVTCGKGTKQRQVWC-QLN---VDHLSDGFCNSSTKPESLSPCELHTC--A 1076
Query: 512 DWMVSEWTGCDT-CLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPALEEPC--------- 560
W V W C T C + R +CV + V+ + C P+ + C
Sbjct: 1077 SWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFIS 1136
Query: 561 --DKDKLPACQV----QWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKE 614
+ LP + QW W+ CSV CG G + R V C A D+S C
Sbjct: 1137 KLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRD---ALDRIADESYCAHL 1193
Query: 615 EKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD--CPKKSL 672
+ + C P C +W A WS C+ SCG G R V+C+ + + C +
Sbjct: 1194 PRPAEIWDCFTP---C-GEWQAGDWSPCSASCGHGKTTRQVLCMNYHQPIDENYCDPEVR 1249
Query: 673 PDSAGSCNEQSC 684
P C+ +C
Sbjct: 1250 PLMEQECSLAAC 1261
Score = 134 bits (325), Expect = 2e-30
Identities = 103/353 (29%), Positives = 153/353 (43%), Gaps = 36/353 (10%)
Query: 352 VTCRSREELEVVDEGLCDDGL-KPATNQTCNT----QACPPQWVP-GNWSRCSKRCGKDG 405
+ +R+E E++ E LC L P + + N ++ W P G W C+K C G
Sbjct: 806 INSTNRQEKEILIEVLCVGNLYNPDVHYSFNIPLEERSDMFTWDPYGPWEGCTKMC--QG 863
Query: 406 TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY-ESCNVDAACPTWFISPWKPCDKL 464
+ R + C I SVV DKEC L P P+ +SCN D W + C
Sbjct: 864 LQRRNITC---IHKSDHSVVSDKECDHL--PLPSFVTQSCNTDCEL-RWHVIGKSECSSQ 917
Query: 465 CGSGQQTRQVVC--YQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEGVDWMVSEWTGC 521
CG G +T + C Y + G+ + D C ++ KP ++ C C W SEW+ C
Sbjct: 918 CGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCHGN-CVFTRWHYSEWSQC 976
Query: 522 D-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKC 580
+C RSR + C+ + + C + E C++ P+ W A++WS+C
Sbjct: 977 SRSCGGGERSRESYCMNNFGHRLADNECQ-ELSRVTRENCNEFSCPS----WAASEWSEC 1031
Query: 581 SVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWS 640
V CG G K R+V+C +V + D C K PCE+ C S W PW
Sbjct: 1032 LVTCGKGTKQRQVWCQ----LNVDHLSDGFCNSSTKPESLSPCEL--HTCAS-WQVGPWG 1084
Query: 641 ECTKSCGKGLRFRSVVCLR----GGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
CT +CG G + R V C+ E ++C + S P SC C + +
Sbjct: 1085 PCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQSCVLTPCSFISK 1137
Score = 107 bits (257), Expect = 4e-22
Identities = 95/383 (24%), Positives = 146/383 (38%), Gaps = 61/383 (15%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
SW +S C TCG G + R V C+ ++ + +G C+ KP + C C W
Sbjct: 1022 SWAASEWSECLVTCGKGTKQRQVWCQLN--VDHLSDGFCNSSTKPESLSPCELHTCA-SW 1078
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK--------PALY 441
G W C+ CG G + R+V+C + + +V++D EC + P P +
Sbjct: 1079 QVGPWGPCTTTCGH-GYQMRDVKCVNELAS---AVLEDTECHEASRPSDRQSCVLTPCSF 1134
Query: 442 ESCNVDAACPT--------WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS 493
S A PT W W PC CG G Q R V C + + + C+
Sbjct: 1135 ISKLETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSC---RDALDRIADESYCA 1191
Query: 494 E-EKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYH 551
+P + C PC +W +W+ C +C +R C+ +YH
Sbjct: 1192 HLPRPAEIWDC-FTPCG--EWQAGDWSPCSASCGHGKTTRQVLCM------------NYH 1236
Query: 552 PTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVD--DS 609
P E CD + P + +CS+ + F + V +
Sbjct: 1237 Q-PIDENYCDPEVRPLME--------QECSLAACPPAHSH------FPSSPVQPSYYLST 1281
Query: 610 NCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCP 668
N P +K D++ V ++W PW +C+ SC GL+ R+VVC G+ S C
Sbjct: 1282 NLPLTQKLEDNENQVVHPSVRGNQWRTGPWGQCSSSCSGGLQHRAVVCQDENGQSASYCD 1341
Query: 669 KKSLPDSAGSCNEQSCEALGEGS 691
S P C C G+
Sbjct: 1342 AASKPPELQQCGPGPCPQWNYGN 1364
Score = 98.7 bits (235), Expect = 2e-19
Identities = 90/329 (27%), Positives = 135/329 (41%), Gaps = 48/329 (14%)
Query: 319 IEKAPLPT----QRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP 374
+E A LPT + W HG+++ CS +CG G Q+R V+CR + + DE C +P
Sbjct: 1138 LETALLPTVLIKKMAQWRHGSWTPCSVSCGRGTQARYVSCRDALD-RIADESYCAHLPRP 1196
Query: 375 ATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLL 434
A C T +W G+WS CS CG G +R+V C +D+ C +
Sbjct: 1197 AEIWDCFTPC--GEWQAGDWSPCSASCG-HGKTTRQVLC-----MNYHQPIDENYCDPEV 1248
Query: 435 GPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE 494
+P + + C++ AACP P + S + + QK L D+E
Sbjct: 1249 --RPLMEQECSL-AACPP--AHSHFPSSPVQPSYYLSTNLPLTQK-------LEDNENQV 1296
Query: 495 EKPLDRQPCELEPCEGVDWMVSEWTGC-DTCLATVRSRVAQCVTKDYRVVNSSFCSYHPT 553
P R G W W C +C ++ R C +D ++S+C
Sbjct: 1297 VHPSVR---------GNQWRTGPWGQCSSSCSGGLQHRAVVC--QDENGQSASYCDAASK 1345
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
P + C P QW W +CS CG G K+R V C +F ++ +D NC
Sbjct: 1346 PPELQQCGPGPCP----QWNYGNWGECSQTCGGGIKSRLVIC-QFPNGQIL--EDHNCEI 1398
Query: 614 EEKYNDSKPCEVPEEKCPS--KWYAAPWS 640
K C + CP+ W+ PW+
Sbjct: 1399 VNKPPSVIQCHM--HACPADVSWHQEPWT 1425
Score = 64.5 bits (150), Expect = 4e-09
Identities = 47/153 (30%), Positives = 60/153 (39%), Gaps = 15/153 (9%)
Query: 372 LKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
L+ NQ + QW G W +CS C G + R V C+ NG + D
Sbjct: 1289 LEDNENQVVHPSVRGNQWRTGPWGQCSSSCS-GGLQHRAVVCQD--ENGQSASYCDA--- 1342
Query: 432 DLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDE 491
KP + C CP W W C + CG G ++R V+C Q NG+I L D
Sbjct: 1343 ---ASKPPELQQCG-PGPCPQWNYGNWGECSQTCGGGIKSRLVIC-QFPNGQI--LEDHN 1395
Query: 492 CS-EEKPLDRQPCELEPCEG-VDWMVSEWTGCD 522
C KP C + C V W WT D
Sbjct: 1396 CEIVNKPPSVIQCHMHACPADVSWHQEPWTSED 1428
Score = 60.5 bits (140), Expect = 6e-08
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 571 QWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
QW W +CS C G + R V C +G S D ++ P E + PC
Sbjct: 1305 QWRTGPWGQCSSSCSGGLQHRAVVCQDENGQSASYCDAASKPPELQQCGPGPC------- 1357
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVC-LRGGKEFSD--CPKKSLPDSAGSCNEQSCEA 686
+W W EC+++CG G++ R V+C G+ D C + P S C+ +C A
Sbjct: 1358 -PQWNYGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACPA 1415
Score = 36.3 bits (80), Expect = 1.2
Identities = 23/68 (33%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWS 395
+SSCS TCGGGI+S C E C + ++CNT +CP
Sbjct: 565 YSSCSRTCGGGIESATRRCNRPEPRN--GGNYCVG--RRMKFRSCNTDSCPKGTQDFREK 620
Query: 396 RCSKRCGK 403
+CS GK
Sbjct: 621 QCSDFNGK 628
>BC061631-1|AAH61631.1| 1686|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 7 protein.
Length = 1686
Score = 291 bits (713), Expect = 2e-77
Identities = 154/430 (35%), Positives = 223/430 (51%), Gaps = 21/430 (4%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQ-CTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CG GV S +R C + P + + C G ++ C Q CP FR QC+ ++
Sbjct: 550 CSRSCGMGVQSAERQCTQPTPKYKGRYCVGERKRFRLCNLQACPAGRPSFRHVQCSHFDA 609
Query: 117 VTFRGKKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCND--DSFDVCVDGVC 174
+ ++G+ + WVP + PCEL C + F + ++ V+DGT C S D+C++G+C
Sbjct: 610 MLYKGQLHTWVPVVNDVNPCELHCRPANEYFAEKLRDAVVDGTPCYQVRASRDLCINGIC 669
Query: 175 QPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYIT 234
+ VGCD + S A ED+C C GNG CHT + GY D+ LIP GA I I
Sbjct: 670 KNVGCDFEIDSGAMEDRCGVCHGNGSTCHTVSGTFEEAE-GLGYVDVGLIPAGAREIRIQ 728
Query: 235 EIEPSNNYLALRSKNGT-YYLNGDYHIDFPRSMTIAGALWNYER--NQQGITAPDKLRSL 291
E+ + N+LALRS++ Y+LNG + I + +AG + Y R N + +T+P
Sbjct: 729 EVAEAANFLALRSEDPEKYFLNGGWTIQWNGDYQVAGTTFTYARRGNWENLTSP------ 782
Query: 292 GPINEPLYLSLLLIDENVGVEYEYSLPIEKA---PLPTQRYSWVHGNFSSCSATCGGGIQ 348
GP EP+++ LL + N GV YEY++ E +P +SW +G ++ C+ TCG G+Q
Sbjct: 783 GPTKEPVWIQLLFQESNPGVHYEYTIHREAGGHDEVPPPVFSWHYGPWTKCTVTCGRGVQ 842
Query: 349 SRDVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTR 407
++V C R + VDE CD +P Q C+ Q CP +W G W CS CG G
Sbjct: 843 RQNVYCLER-QAGPVDEEHCDPLGRPDDQQRKCSEQPCPARWWAGEWQLCSSSCGPGGLS 901
Query: 408 SREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP-TWFISPWKPCDKLCG 466
R V C + + S ++ C L P+P CN CP TW + W C CG
Sbjct: 902 RRAVLCIRSVGLDEQSALEPPACEHL--PRPPTETPCNRHVPCPATWAVGNWSQCSVTCG 959
Query: 467 SGQQTRQVVC 476
G Q R V+C
Sbjct: 960 EGTQRRNVLC 969
Score = 109 bits (262), Expect = 1e-22
Identities = 73/243 (30%), Positives = 105/243 (43%), Gaps = 31/243 (12%)
Query: 323 PLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNT 382
PL + W GN+S CS TCG G R V C S + + G +P + C+
Sbjct: 1407 PLVVRNAGWQAGNWSECSTTCGLGAVWRPVRCSSGRDEDCAPAG------RPQPARRCHL 1460
Query: 383 QACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP-KPALY 441
+ C W GNWS+CS+ CG G+ R+V+C + T L + + GP KP +
Sbjct: 1461 RPC-ATWHSGNWSKCSRSCG-GGSSVRDVQC--VDTRDLRPL---RPFHCQPGPAKPPAH 1513
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
C C +W+ S W+ C + CG G+Q R V C + C E +P
Sbjct: 1514 RPCGAQ-PCLSWYTSSWRECSEACGGGEQQRLVTCPEPG----------LCEEALRPNTT 1562
Query: 501 QPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRV--VNSSFCSYHPTPALE 557
+PC PC W+V W C C V+ R+ +CV + +S C + P
Sbjct: 1563 RPCNTHPC--TQWVVGPWGQCSGPCGGGVQRRLVKCVNTQTGLPEEDSDQCGHEAWPESS 1620
Query: 558 EPC 560
PC
Sbjct: 1621 RPC 1623
Score = 99 bits (238), Expect = 9e-20
Identities = 70/242 (28%), Positives = 104/242 (42%), Gaps = 36/242 (14%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEGV 511
W W C CG G R V C ++GR D++C+ +P + C L PC
Sbjct: 1415 WQAGNWSECSTTCGLGAVWRPVRC---SSGR-----DEDCAPAGRPQPARRCHLRPC--A 1464
Query: 512 DWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFCSYHPT-PALEEPCDKDKLPAC 568
W W+ C +C R QCV T+D R + C P P PC C
Sbjct: 1465 TWHSGNWSKCSRSCGGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPPAHRPCGAQP---C 1521
Query: 569 QVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEE 628
+ WY + W +CS CG G++ R V C + C + + N ++PC
Sbjct: 1522 -LSWYTSSWRECSEACGGGEQQRLVTCP----------EPGLCEEALRPNTTRPCNT--H 1568
Query: 629 KCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG----GKEFSD-CPKKSLPDSAGSCNEQS 683
C ++W PW +C+ CG G++ R V C+ +E SD C ++ P+S+ C +
Sbjct: 1569 PC-TQWVVGPWGQCSGPCGGGVQRRLVKCVNTQTGLPEEDSDQCGHEAWPESSRPCGTED 1627
Query: 684 CE 685
CE
Sbjct: 1628 CE 1629
Score = 99 bits (238), Expect = 9e-20
Identities = 61/185 (32%), Positives = 79/185 (42%), Gaps = 19/185 (10%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDG-LKPATNQTCNTQACPPQ 388
+W GN+S CS +CGGG RDV C +L + C G KP ++ C Q C
Sbjct: 1465 TWHSGNWSKCSRSCGGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPPAHRPCGAQPCL-S 1523
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W +W CS+ CG G + R V C + P + C + L P CN
Sbjct: 1524 WYTSSWRECSEACG-GGEQQRLVTCPE------PGL-----CEEALRPNTT--RPCNTHP 1569
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK-PLDRQPCELEP 507
C W + PW C CG G Q R V C G + D+C E P +PC E
Sbjct: 1570 -CTQWVVGPWGQCSGPCGGGVQRRLVKCVNTQTG-LPEEDSDQCGHEAWPESSRPCGTED 1627
Query: 508 CEGVD 512
CE V+
Sbjct: 1628 CEPVE 1632
Score = 81.4 bits (192), Expect = 3e-14
Identities = 48/172 (27%), Positives = 73/172 (42%), Gaps = 17/172 (9%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQ-PCELEPCE 509
+W PW C CG G Q + V C ++ G ++ ++ C +P D+Q C +PC
Sbjct: 824 SWHYGPWTKCTVTCGRGVQRQNVYCLERQAGPVD---EEHCDPLGRPDDQQRKCSEQPCP 880
Query: 510 GVDWMVSEWTGCDTCLAT--VRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKD 563
W EW C + + R C+ + + C + P P E PC++
Sbjct: 881 -ARWWAGEWQLCSSSCGPGGLSRRAVLCIRSVGLDEQSALEPPACEHLPRPPTETPCNR- 938
Query: 564 KLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEE 615
+P C W WS+CSV CG G + R V C G + D++ P E
Sbjct: 939 HVP-CPATWAVGNWSQCSVTCGEGTQRRNVLCTNDTG---VPCDEAQQPASE 986
Score = 74.9 bits (176), Expect = 3e-12
Identities = 52/188 (27%), Positives = 78/188 (41%), Gaps = 13/188 (6%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W WT C TC V+ + C+ + V+ C P ++ K C +
Sbjct: 825 WHYGPWTKCTVTCGRGVQRQNVYCLERQAGPVDEEHCD--PLGRPDDQQRKCSEQPCPAR 882
Query: 572 WYATQWSKCSVECGVGKKTRR-VFCGKFDGASVMK-VDDSNCPKEEKYNDSKPCEVPEEK 629
W+A +W CS CG G +RR V C + G ++ C + PC
Sbjct: 883 WWAGEWQLCSSSCGPGGLSRRAVLCIRSVGLDEQSALEPPACEHLPRPPTETPCN-RHVP 941
Query: 630 CPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCE---- 685
CP+ W WS+C+ +CG+G + R+V+C C + P S +C+ C
Sbjct: 942 CPATWAVGNWSQCSVTCGEGTQRRNVLCT--NDTGVPCDEAQQPASEVTCSLPLCRWPLG 999
Query: 686 ALG-EGSG 692
LG EGSG
Sbjct: 1000 TLGPEGSG 1007
Score = 70.1 bits (164), Expect = 8e-11
Identities = 32/98 (32%), Positives = 55/98 (56%), Gaps = 5/98 (5%)
Query: 563 DKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP 622
D++P W+ W+KC+V CG G + + V+C + VD+ +C + +D +
Sbjct: 816 DEVPPPVFSWHYGPWTKCTVTCGRGVQRQNVYCLERQAG---PVDEEHCDPLGRPDDQQR 872
Query: 623 CEVPEEKCPSKWYAAPWSECTKSCGK-GLRFRSVVCLR 659
+ E+ CP++W+A W C+ SCG GL R+V+C+R
Sbjct: 873 -KCSEQPCPARWWAGEWQLCSSSCGPGGLSRRAVLCIR 909
Score = 57.2 bits (132), Expect = 6e-07
Identities = 38/127 (29%), Positives = 54/127 (42%), Gaps = 16/127 (12%)
Query: 563 DKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP 622
D L W A WS+CS CG+G R V C G D +C + ++
Sbjct: 1406 DPLVVRNAGWQAGNWSECSTTCGLGAVWRPVRCSS--GR------DEDCAPAGRPQPARR 1457
Query: 623 CEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPDSAG 677
C + C + W++ WS+C++SCG G R V C LR + F P + P +
Sbjct: 1458 CHL--RPCAT-WHSGNWSKCSRSCGGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPPAHR 1514
Query: 678 SCNEQSC 684
C Q C
Sbjct: 1515 PCGAQPC 1521
Score = 48.0 bits (109), Expect = 4e-04
Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 8/57 (14%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGL-CDDGLKPATNQTCNTQAC 385
+W GN+S CS TCG G Q R+V C + D G+ CD+ +PA+ TC+ C
Sbjct: 945 TWAVGNWSQCSVTCGEGTQRRNVLCTN-------DTGVPCDEAQQPASEVTCSLPLC 994
Score = 44.0 bits (99), Expect = 0.006
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Query: 634 WYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
W A WSEC+ +CG G +R V C G E DC P A C+ + C G+
Sbjct: 1415 WQAGNWSECSTTCGLGAVWRPVRCSSGRDE--DCAPAGRPQPARRCHLRPCATWHSGN 1470
Score = 33.9 bits (74), Expect = 6.3
Identities = 20/50 (40%), Positives = 22/50 (44%), Gaps = 5/50 (10%)
Query: 56 TPCSRTCGGGVASQKRICLE--IGPNGEPQCT---GGDTKYFSCETQDCP 100
T C+ TCG GV Q CLE GP E C D + C Q CP
Sbjct: 831 TKCTVTCGRGVQRQNVYCLERQAGPVDEEHCDPLGRPDDQQRKCSEQPCP 880
>AJ311904-1|CAC84565.1| 1207|Homo sapiens ADAMTS-19 protein.
Length = 1207
Score = 291 bits (713), Expect = 2e-77
Identities = 178/523 (34%), Positives = 258/523 (49%), Gaps = 36/523 (6%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN 115
+PCSRTC G++S++R C + C G +Y CE CP FR QC Y+
Sbjct: 643 SPCSRTCSAGISSRERKCPGLDSEAR-DCNGPRKQYRICENPPCPAGLPGFRDWQCQAYS 701
Query: 116 NVTFRGKKY-RWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVC 174
T K +W L KPC L C G EKV+DGT C D+C +G C
Sbjct: 702 VRTSSPKHILQWQAVLDEEKPCALFCSPVGKEQPILLSEKVMDGTSCGYQGLDICANGRC 761
Query: 175 QPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYIT 234
Q VGCD +LGS A+ED C C GNG +C K N GY ++L+IP GA I +
Sbjct: 762 QKVGCDGLLGSLAREDHCGVCNGNGKSCKIIKGDFN-HTRGAGYVEVLVIPAGARRIKVV 820
Query: 235 EIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPI 294
E +P+++YLALR G +N D+ I+ + +AG +Y R +G+ +K+ + GP
Sbjct: 821 EEKPAHSYLALRDA-GKQSINSDWKIEHSGAFNLAGTTVHYVR--RGLW--EKISAKGPT 875
Query: 295 NEPLYLSLLLI-DENVGVEYEYSLPIEKAP------LPTQRYSWVHGNFSSCSATCGGGI 347
PL+L +LL D+N G+ YEY++P + P P + W H ++ C ATCGGG
Sbjct: 876 TAPLHLLVLLFQDQNYGLHYEYTIPSDPLPENQSSKAPEPLFMWTHTSWEDCDATCGGGE 935
Query: 348 QSRDVTCRS--REELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSRCSKRCGKD 404
+ V+C + + +VD C KP + CN Q C +W+ W+ CS+ CGK
Sbjct: 936 RKTTVSCTKIMSKNISIVDNEKCKYLTKPEPQIRKCNEQPCQTRWMMTEWTPCSRTCGK- 994
Query: 405 GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKL 464
G +SR+V C + ++NG +++C +GPKPA + C W W
Sbjct: 995 GMQSRQVACTQQLSNGTLIRARERDC---IGPKPASAQRCEGQDCMTVWEAGVWSEFSVK 1051
Query: 465 CGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-T 523
CG G + R V C N + VLS +P + + CE + + W + +W+ C T
Sbjct: 1052 CGKGIRHRTVRC--TNPRKKCVLS------TRPREAEDCE-DYSKCYVWRMGDWSKCSIT 1102
Query: 524 CLATVRSRVAQCVTK-DYRVVNSSFCSYHPT---PALEEPCDK 562
C ++SRV QC+ K R N F S P P +PC++
Sbjct: 1103 CGKGMQSRVIQCMHKITGRHGNECFSSEKPAAYRPCHLQPCNE 1145
Score = 101 bits (241), Expect = 4e-20
Identities = 68/240 (28%), Positives = 112/240 (46%), Gaps = 23/240 (9%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDR-QPCELEPCEG 510
W + W+ CD CG G++ V C + + I+++ +++C KP + + C +PC+
Sbjct: 919 WTHTSWEDCDATCGGGERKTTVSCTKIMSKNISIVDNEKCKYLTKPEPQIRKCNEQPCQ- 977
Query: 511 VDWMVSEWTGCD-TCLATVRSRVAQC---VTKDYRVVNSSFCSYHPTPALEEPCDKDKLP 566
WM++EWT C TC ++SR C ++ + P PA + C+
Sbjct: 978 TRWMMTEWTPCSRTCGKGMQSRQVACTQQLSNGTLIRARERDCIGPKPASAQRCEGQD-- 1035
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVP 626
C W A WS+ SV+CG G + R V C V+ S P+E ++ CE
Sbjct: 1036 -CMTVWEAGVWSEFSVKCGKGIRHRTVRCTNPRKKCVL----STRPRE-----AEDCE-D 1084
Query: 627 EEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR--GGKEFSDCPKKSLPDSAGSCNEQSC 684
KC W WS+C+ +CGKG++ R + C+ G+ ++C P + C+ Q C
Sbjct: 1085 YSKC-YVWRMGDWSKCSITCGKGMQSRVIQCMHKITGRHGNECFSSEKPAAYRPCHLQPC 1143
Score = 68.9 bits (161), Expect = 2e-10
Identities = 45/148 (30%), Positives = 62/148 (41%), Gaps = 16/148 (10%)
Query: 552 PTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNC 611
P+ L E K P W T W C CG G++ V C K ++ VD+ C
Sbjct: 900 PSDPLPEN-QSSKAPEPLFMWTHTSWEDCDATCGGGERKTTVSCTKIMSKNISIVDNEKC 958
Query: 612 PKEEKYNDS-KPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC---LRGG----KE 663
K + C E+ C ++W W+ C+++CGKG++ R V C L G
Sbjct: 959 KYLTKPEPQIRKCN--EQPCQTRWMMTEWTPCSRTCGKGMQSRQVACTQQLSNGTLIRAR 1016
Query: 664 FSDC--PKKSLPDSAGSCNEQSCEALGE 689
DC PK P SA C Q C + E
Sbjct: 1017 ERDCIGPK---PASAQRCEGQDCMTVWE 1041
>AL356356-13|CAI15500.2| 1074|Homo sapiens ADAMTS-like 4 protein.
Length = 1074
Score = 289 bits (710), Expect = 5e-77
Identities = 192/629 (30%), Positives = 275/629 (43%), Gaps = 44/629 (6%)
Query: 82 PQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNVTFRGKKYRWVPYLKV--SKPCELT 139
P+C+G + +C CP D RA QCA +N+ F G+ Y+W P+ +V S+ CEL
Sbjct: 362 PRCSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQLYQWEPFTEVQGSQRCELN 421
Query: 140 CMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNG 199
C G RFY RH EKV DGT C + D+CV G C GCD +LGS + D C C G+
Sbjct: 422 CRPRGFRFYVRHTEKVQDGTLCQPGAPDICVAGRCLSPGCDGILGSGRRPDGCGVCGGDD 481
Query: 200 HNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYH 259
C + + GY IL IP GA + I ++ PS+NYLALR G +NG++
Sbjct: 482 STCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWA 541
Query: 260 IDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL-- 317
+D P S G ++ Y R + + L + GP +P+ + ++ +EN GV Y+Y +
Sbjct: 542 VDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIFQEENPGVFYQYVISS 601
Query: 318 --PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA 375
PI + P P + + + ++ + PA
Sbjct: 602 PPPILENPTPEPPVPQLQPEILRVEPPLAPAPRPARTPGTLQRQVRIPQ--------MPA 653
Query: 376 TNQTCNTQACP-PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLL 434
P W S CS CGK G C I+ +D++ C
Sbjct: 654 PPHPRTPLGSPAAYWKRVGHSACSASCGK-GVWRPIFLC---ISRESGEELDERSCAAGA 709
Query: 435 GPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE 494
P PA E C+ P W W C + CG G Q RQ+ C Q+ G + + + C
Sbjct: 710 RP-PASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGH 768
Query: 495 -EKPLDRQPCELEPCEGVDWMV-SEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFC-SY 550
+P Q C+L C W V S W+ C C RSR +CV + V+ C S
Sbjct: 769 LPRPNITQSCQLRLCG--HWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASG 826
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQW-SKCSVECGVGKKTRRVFC-------GKFDGAS 602
P P E CD + C W+ + W SKCS ECG G + R V C G G +
Sbjct: 827 PPQPPSREACD---MGPCTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEA 883
Query: 603 VMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGG 661
S CP + D + C + + +WY PW EC+ CG G + R ++C+ + G
Sbjct: 884 GAGTGQS-CPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLG 942
Query: 662 KEF-----SDCPKKSLPDSAGSCNEQSCE 685
EF S+C P + C Q+C+
Sbjct: 943 TEFNVTSPSNCSHLPRPPALQPCQGQACQ 971
Score = 199 bits (485), Expect = 1e-49
Identities = 120/382 (31%), Positives = 179/382 (46%), Gaps = 26/382 (6%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PAT 376
P + PL + W S+CSA+CG G+ C SRE E +DE C G + PA+
Sbjct: 655 PHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPAS 714
Query: 377 NQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP 436
+ C+ CPP W G W+ CS+ CG GT+ R+++C + G SV ++ C L P
Sbjct: 715 PEPCHGTPCPPYWEAGEWTSCSRSCG-PGTQHRQLQCRQEFGGGGSSVPPER-CGHL--P 770
Query: 437 KPALYESCNVDAACPTWFI-SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE- 494
+P + +SC + C W + SPW C CG GQ++RQV C NNG + +S+ EC+
Sbjct: 771 RPNITQSCQL-RLCGHWEVGSPWSQCSVRCGRGQRSRQVRCV-GNNG--DEVSEQECASG 826
Query: 495 -EKPLDRQPCELEPCEGVDWMVSEWTG-CDT-CLATVRSRVAQCVTKDYRV------VNS 545
+P R+ C++ PC W S+W+ C C ++ R C+ + +
Sbjct: 827 PPQPPSREACDMGPCT-TAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGA 885
Query: 546 SFCSYHPTPALEEPCDKDKLPACQ--VQWYATQWSKCSVECGVGKKTRRVFCGKFDGASV 603
PT + L C+ +WY W +CS ECG G + R + C G
Sbjct: 886 GTGQSCPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEF 945
Query: 604 MKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKE 663
SNC + +PC+ + C +W++ PWS C++SC G + R V CL +
Sbjct: 946 NVTSPSNCSHLPRPPALQPCQ--GQACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQT 1003
Query: 664 FSD-CPKKSLPDSAGSCNEQSC 684
S CP + P CN Q C
Sbjct: 1004 LSTRCPPQLRPSRKRPCNSQPC 1025
>AF140674-1|AAD56357.1| 860|Homo sapiens zinc metalloprotease
ADAMTS6 protein.
Length = 860
Score = 276 bits (676), Expect = 7e-73
Identities = 132/317 (41%), Positives = 189/317 (59%), Gaps = 9/317 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQ-CTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV+S R C P+G + C G +Y SC T CP S DFR +QCA ++N
Sbjct: 522 CSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDN 581
Query: 117 VTFRGKKYRWVPYLKVS-KPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQ 175
+ FRGK Y W PY KPC L C+ G FY VIDGT+CN DS D+C++G C+
Sbjct: 582 MPFRGKYYNWKPYTGGGVKPCALNCLAEGYNFYTERAPAVIDGTQCNADSLDICINGECK 641
Query: 176 PVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITE 235
VGCD +LGS+A+ED+CR C G G C + N R GY +++ IP G+ I + E
Sbjct: 642 HVGCDNILGSDAREDRCRVCGGGGSTCDAIEGFFNDSLPRGGYMEVVQIPRGSVHIEVRE 701
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPIN 295
+ S NY+AL+S+ YY+NG + ID+PR +AG ++Y+R P+ L +LGP +
Sbjct: 702 VAMSKNYIALKSEGDDYYINGAWTIDWPRKFDVAGTAFHYKRPTD---EPESLEALGPTS 758
Query: 296 EPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQR--YSWVHGNFSSCSATCGGG-IQSRDV 352
E L + +LL ++N+G+ Y++++PI + ++W H +S CSATC GG + +R
Sbjct: 759 ENLIVMVLLQEQNLGIRYKFNVPITRTGSGDNEVGFTWNHQPWSECSATCAGGKMPTRQP 818
Query: 353 TCRSR-EELEVVDEGLC 368
T R+R ++ LC
Sbjct: 819 TQRARWRTKHILSYALC 835
>AF261918-1|AAF89106.1| 1072|Homo sapiens disintegrin
metalloproteinase with thrombospondin repeats protein.
Length = 1072
Score = 272 bits (667), Expect = 9e-72
Identities = 167/486 (34%), Positives = 245/486 (50%), Gaps = 38/486 (7%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN- 115
CSRTCGGG+ + R C P NG C G K+ SC T+ C + DFR EQCA ++
Sbjct: 600 CSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPCLKQKRDFRDEQCAHFDG 659
Query: 116 ---NVTFRGKKYRWVPY---LKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
N+ RWVP + + C+L C G+ YY+ +++VIDGT C D+ D+C
Sbjct: 660 KHFNINGLLPNVRWVPKYSGILMKDRCKLFCRVAGNTAYYQLRDRVIDGTPCGQDTNDIC 719
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGAT 229
V G+C+ GCD +L S A+ DKC C G+ +C T NT + GYN ++ IP GAT
Sbjct: 720 VQGLCRQAGCDHVLNSKARRDKCGVCGGDNSSCKTVAGTFNT--VHYGYNTVVRIPAGAT 777
Query: 230 TIYITEIEPS-----NNYLALRSKNGTYYLNGDYHIDF-PRSMTIAGALWNYERNQQGIT 283
I + + S +NYLAL S G + LNG++ + R + I A+ Y ++ T
Sbjct: 778 NIDVRQHSFSGETDDDNYLALSSSKGEFLLNGNFVVTMAKREIRIGNAVVEYSGSE---T 834
Query: 284 APDKLRSLGPINEPLYLSLLLIDE--NVGVEYEYSLPIEKAPLPTQRYSW-VHGNFSSCS 340
A +++ S I + L L +L + + N V Y +++PIE P Q++ W HG + +CS
Sbjct: 835 AVERINSTDRIEQELLLQVLSVGKLYNPDVRYSFNIPIEDKP---QQFYWNSHGPWQACS 891
Query: 341 ATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACPPQWVPGNWSRCSK 399
C G + + V R ++L V D+ CD +P + C T C +W + S CS
Sbjct: 892 KPCQGERKRKLVCTRESDQLTVSDQ-RCDRLPQPGHITEPCGTD-CDLRWHVASRSECSA 949
Query: 400 RCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPW 458
+CG G R+ ++ C K +G VDD C PKP+ E C+ + W S W
Sbjct: 950 QCGL-GYRTLDIYCAKYSRLDGKTEKVDDGFCSS--HPKPSNREKCSGECNTGGWRYSAW 1006
Query: 459 KPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC---EGVDWMV 515
C K C G Q R+ +C N R +VL D +C+ ++ + Q C PC + DW
Sbjct: 1007 TECSKSCDGGTQRRRAICV---NTRNDVLDDSKCTHQEKVTIQRCSEFPCPQWKSGDWSE 1063
Query: 516 SEWTGC 521
W GC
Sbjct: 1064 VRWEGC 1069
Score = 81.4 bits (192), Expect = 3e-14
Identities = 45/156 (28%), Positives = 68/156 (43%), Gaps = 10/156 (6%)
Query: 518 WTGCDTCLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCDKDKLPACQVQWYAT 575
W C R R C + D V+ C P P + EPC D C ++W+
Sbjct: 887 WQACSKPCQGERKRKLVCTRESDQLTVSDQRCDRLPQPGHITEPCGTD----CDLRWHVA 942
Query: 576 QWSKCSVECGVGKKTRRVFCGKFD--GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
S+CS +CG+G +T ++C K+ KVDD C K ++ + C E
Sbjct: 943 SRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCS--GECNTGG 1000
Query: 634 WYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPK 669
W + W+EC+KSC G + R +C+ + D K
Sbjct: 1001 WRYSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSK 1036
Score = 70.9 bits (166), Expect = 5e-11
Identities = 60/197 (30%), Positives = 88/197 (44%), Gaps = 31/197 (15%)
Query: 457 PWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCEL-EPCEGVD--- 512
PW+ C K C G++ R++VC ++++ ++ V SD C + P QP + EPC G D
Sbjct: 886 PWQACSKPC-QGERKRKLVCTRESD-QLTV-SDQRC-DRLP---QPGHITEPC-GTDCDL 937
Query: 513 -WMVSEWTGCDT-CLATVRSRVAQCVTKDY-----RVVNSSFCSYHPTPALEEPCDKDKL 565
W V+ + C C R+ C V+ FCS HP P+ E C +
Sbjct: 938 RWHVASRSECSAQCGLGYRTLDIYCAKYSRLDGKTEKVDDGFCSSHPKPSNREKCSGE-- 995
Query: 566 PACQVQ-WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCE 624
C W + W++CS C G + RR C + DDS C +EK + E
Sbjct: 996 --CNTGGWRYSAWTECSKSCDGGTQRRRAICVNTRNDVL---DDSKCTHQEKVTIQRCSE 1050
Query: 625 VPEEKCPSKWYAAPWSE 641
P CP +W + WSE
Sbjct: 1051 FP---CP-QWKSGDWSE 1063
>BC132735-1|AAI32736.1| 1205|Homo sapiens ADAMTS3 protein protein.
Length = 1205
Score = 256 bits (627), Expect = 6e-67
Identities = 156/473 (32%), Positives = 221/473 (46%), Gaps = 42/473 (8%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG GV + R C P NG C G + +Y C T++C ++ DFRA+QC Q N+
Sbjct: 563 CSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNS 622
Query: 117 -VTFRGKKYRWVPYLKVS--KPCELTCM--QHGDRFYYRHKEKVIDGTRCN-DDSFDVCV 170
++ K+ W+PY K C L C + GD Y K+ V DGT C+ D + +CV
Sbjct: 623 HFEYQNTKHHWLPYEHPDPKKRCHLYCQSKETGDVAYM--KQLVHDGTHCSYKDPYSICV 680
Query: 171 DGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATT 230
G C VGCD +GSN EDKC C G+ +C T K + GY + IP GA
Sbjct: 681 RGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARH 740
Query: 231 IYITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLR 289
+ I E E S + LA++++ G Y LNG R+ G W+Y + L
Sbjct: 741 VLIQEDEASPHILAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDD----IESLH 796
Query: 290 SLGPINEPLYLSLLLIDENVGVEYEYSLPIEKAPLPT-----------QRYSWVHGNFSS 338
+ GP+++P+ + ++ + + Y I + +PT + W ++S
Sbjct: 797 TDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQ 856
Query: 339 CSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQACP-PQWVPGNWSR 396
CS CGGG Q CR + + ++V C+ KP + CN Q C P WV W
Sbjct: 857 CSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPLWVAEEWEH 916
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFI 455
C+K CG G + R VRC + + +G V K C +G +P CN CP W
Sbjct: 917 CTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYC---MGDRPESRRPCN-RVPCPAQWKT 972
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
PW C CG G + RQV+C + D C EKP + C+L PC
Sbjct: 973 GPWSECSVTCGEGTEVRQVLC----------RAGDHCDGEKPESVRACQLPPC 1015
Score = 83.0 bits (196), Expect = 1e-14
Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVD 512
W + W C K CG G Q + C +K++ ++ S E +++ R+ C ++ C
Sbjct: 849 WALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPL 908
Query: 513 WMVSEWTGC-DTCLAT-VRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDKLP 566
W+ EW C TC ++ + R +C+ R V+S +C P PC +++P
Sbjct: 909 WVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYC-MGDRPESRRPC--NRVP 965
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C QW WS+CSV CG G + R+V C D K + + ND +PC
Sbjct: 966 -CPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCND-EPC 1020
Score = 80.6 bits (190), Expect = 6e-14
Identities = 57/190 (30%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV- 446
+W +WS+CSK CG G + + C + N +V C PKP + CN+
Sbjct: 848 EWALKSWSQCSKPCG-GGFQYTKYGCRRKSDN---KMVHRSFCEANKKPKP-IRRMCNIQ 902
Query: 447 DAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKN-NGRINVLSDDECSEEKPLDRQPCE 504
+ P W W+ C K CGS G Q R V C Q +G + C ++P R+PC
Sbjct: 903 ECTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESRRPCN 962
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDY--RVVNSSFCSYHPTPALEEPCD 561
PC W W+ C TC R C D+ S + P +EPC
Sbjct: 963 RVPCPA-QWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCNDEPCL 1021
Query: 562 KDKLPACQVQ 571
DK CQ++
Sbjct: 1022 GDKSIFCQME 1031
Score = 77.4 bits (182), Expect = 5e-13
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 16/193 (8%)
Query: 506 EPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCDK 562
E + +W + W+ C C + C K D ++V+ SFC + P + C+
Sbjct: 842 EELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNI 901
Query: 563 DKLPACQVQWYATQWSKCSVECGV-GKKTRRVFCGK--FDGASVMKVDDSNCPKEEKYND 619
+ W A +W C+ CG G + R V C + DG + V C ++
Sbjct: 902 QE--CTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTN-RSVHSKYC-MGDRPES 957
Query: 620 SKPCE-VPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGS 678
+PC VP CP++W PWSEC+ +CG+G R V+C G + P+
Sbjct: 958 RRPCNRVP---CPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPP 1014
Query: 679 CNEQSCEALGEGS 691
CN++ C LG+ S
Sbjct: 1015 CNDEPC--LGDKS 1025
Score = 35.9 bits (79), Expect = 1.6
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 625 VPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGG------KEFSDCPKKSLPDSAGS 678
+ EE +W WS+C+K CG G ++ C R + F + KK P
Sbjct: 840 IQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKP-IRRM 898
Query: 679 CNEQSC 684
CN Q C
Sbjct: 899 CNIQEC 904
>BC130287-1|AAI30288.1| 1205|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 3 protein.
Length = 1205
Score = 256 bits (627), Expect = 6e-67
Identities = 156/473 (32%), Positives = 221/473 (46%), Gaps = 42/473 (8%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG GV + R C P NG C G + +Y C T++C ++ DFRA+QC Q N+
Sbjct: 563 CSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNS 622
Query: 117 -VTFRGKKYRWVPYLKVS--KPCELTCM--QHGDRFYYRHKEKVIDGTRCN-DDSFDVCV 170
++ K+ W+PY K C L C + GD Y K+ V DGT C+ D + +CV
Sbjct: 623 HFEYQNTKHHWLPYEHPDPKKRCHLYCQSKETGDVAYM--KQLVHDGTHCSYKDPYSICV 680
Query: 171 DGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATT 230
G C VGCD +GSN EDKC C G+ +C T K + GY + IP GA
Sbjct: 681 RGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARH 740
Query: 231 IYITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLR 289
+ I E E S + LA++++ G Y LNG R+ G W+Y + L
Sbjct: 741 VLIQEDEASPHILAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDD----IESLH 796
Query: 290 SLGPINEPLYLSLLLIDENVGVEYEYSLPIEKAPLPT-----------QRYSWVHGNFSS 338
+ GP+++P+ + ++ + + Y I + +PT + W ++S
Sbjct: 797 TDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQ 856
Query: 339 CSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQACP-PQWVPGNWSR 396
CS CGGG Q CR + + ++V C+ KP + CN Q C P WV W
Sbjct: 857 CSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPLWVAEEWEH 916
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFI 455
C+K CG G + R VRC + + +G V K C +G +P CN CP W
Sbjct: 917 CTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYC---MGDRPESRRPCN-RVPCPAQWKT 972
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
PW C CG G + RQV+C + D C EKP + C+L PC
Sbjct: 973 GPWSECSVTCGEGTEVRQVLC----------RAGDHCDGEKPESVRACQLPPC 1015
Score = 83.0 bits (196), Expect = 1e-14
Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVD 512
W + W C K CG G Q + C +K++ ++ S E +++ R+ C ++ C
Sbjct: 849 WALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPL 908
Query: 513 WMVSEWTGC-DTCLAT-VRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDKLP 566
W+ EW C TC ++ + R +C+ R V+S +C P PC +++P
Sbjct: 909 WVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYC-MGDRPESRRPC--NRVP 965
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C QW WS+CSV CG G + R+V C D K + + ND +PC
Sbjct: 966 -CPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCND-EPC 1020
Score = 80.6 bits (190), Expect = 6e-14
Identities = 57/190 (30%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV- 446
+W +WS+CSK CG G + + C + N +V C PKP + CN+
Sbjct: 848 EWALKSWSQCSKPCG-GGFQYTKYGCRRKSDN---KMVHRSFCEANKKPKP-IRRMCNIQ 902
Query: 447 DAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKN-NGRINVLSDDECSEEKPLDRQPCE 504
+ P W W+ C K CGS G Q R V C Q +G + C ++P R+PC
Sbjct: 903 ECTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESRRPCN 962
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDY--RVVNSSFCSYHPTPALEEPCD 561
PC W W+ C TC R C D+ S + P +EPC
Sbjct: 963 RVPCPA-QWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCNDEPCL 1021
Query: 562 KDKLPACQVQ 571
DK CQ++
Sbjct: 1022 GDKSIFCQME 1031
Score = 77.4 bits (182), Expect = 5e-13
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 16/193 (8%)
Query: 506 EPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCDK 562
E + +W + W+ C C + C K D ++V+ SFC + P + C+
Sbjct: 842 EELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNI 901
Query: 563 DKLPACQVQWYATQWSKCSVECGV-GKKTRRVFCGK--FDGASVMKVDDSNCPKEEKYND 619
+ W A +W C+ CG G + R V C + DG + V C ++
Sbjct: 902 QE--CTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTN-RSVHSKYC-MGDRPES 957
Query: 620 SKPCE-VPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGS 678
+PC VP CP++W PWSEC+ +CG+G R V+C G + P+
Sbjct: 958 RRPCNRVP---CPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPP 1014
Query: 679 CNEQSCEALGEGS 691
CN++ C LG+ S
Sbjct: 1015 CNDEPC--LGDKS 1025
Score = 35.9 bits (79), Expect = 1.6
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 7/66 (10%)
Query: 625 VPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGG------KEFSDCPKKSLPDSAGS 678
+ EE +W WS+C+K CG G ++ C R + F + KK P
Sbjct: 840 IQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKP-IRRM 898
Query: 679 CNEQSC 684
CN Q C
Sbjct: 899 CNIQEC 904
>BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein.
Length = 1691
Score = 255 bits (624), Expect = 1e-66
Identities = 193/706 (27%), Positives = 307/706 (43%), Gaps = 104/706 (14%)
Query: 54 DVTPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQ 113
D + CSRTCGGG + R CL G N C G + +Y +C DCP ++ DFRA+QC+
Sbjct: 83 DWSDCSRTCGGGASYSLRRCLT-GRN----CEGQNIRYKTCSNHDCPPDAEDFRAQQCSA 137
Query: 114 YNNVTFRGKKYRWVP-YLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDG 172
YN+V ++G+ Y W+P Y + PC L C G KV+DGTRCN DS D+C+ G
Sbjct: 138 YNDVQYQGRYYEWLPRYNDPAAPCALKCHAQGQNLVVELAPKVLDGTRCNTDSLDMCISG 197
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQ-DLRKGYNDILLIPEGATTI 231
+CQ VGCD LGSNAKED C C G+G C + + K +++ +P G+ ++
Sbjct: 198 ICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSV 257
Query: 232 YITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSL 291
IT P++ ++ ++ G+ G++ + P + ++R + T +
Sbjct: 258 RITVKGPAHLFIESKTLQGS---KGEHSFNSPGVFVVENTTVEFQRGSERQT----FKIP 310
Query: 292 GPI-NEPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSR 350
GP+ + ++ + ++ V++ + PI + W +F C+ TCGGG Q
Sbjct: 311 GPLMADFIFKTRYTAAKDSVVQFFFYQPIS--------HQWRQTDFFPCTVTCGGGYQLN 362
Query: 351 DVTCRSREELEVVDEGLC---DDGLKPATN-QTCNTQACP-----------------PQW 389
C VV + C + +KP + C+ CP P+W
Sbjct: 363 SAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSDGFKEIMPYDHFQPLPRW 422
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
W+ CS CG G + R C + +G V++ +C + PKP + ++CN+
Sbjct: 423 EHNPWTACSVSCG-GGIQRRSFVCVEESMHGEILQVEEWKC--MYAPKPKVMQTCNL-FD 478
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKN-------NGRINVLSDDEC---------S 493
CP W W C CG G + R V+C N ++ + +EC
Sbjct: 479 CPKWIAMEWSQCTVTCGRGLRYRVVLCINHRGEHVGGCNPQLKLHIKEECVIPIPCYKPK 538
Query: 494 EEKPLD------RQPCELE----PCEGVDWMVSEWTGCD-TC-----LATVRSRVAQCVT 537
E+ P++ +Q ELE E ++ W+ C TC + V+ RV T
Sbjct: 539 EKSPVEAKLPWLKQAQELEETRIATEEPTFIPEPWSACSTTCGPGVQVREVKCRVLLTFT 598
Query: 538 KDYRVVNSSFCS--YHPT--PALEEPCDKD--------KLP---ACQVQWYATQWSKCSV 582
+ + C PT P L E CD+ LP W ++ C+
Sbjct: 599 QTETELPEEECEGPKLPTERPCLLEACDESPASRELDIPLPEDSETTYDWEYAGFTPCTA 658
Query: 583 ECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND-SKPCEVPEEKCPSKWYAAPWSE 641
C G + C + V+DS C + S+ C E CP +W+ W
Sbjct: 659 TCLGGHQEAIAVCLHIQ--TQQTVNDSLCDMVHRPPAMSQACNT--EPCPPRWHVGSWGP 714
Query: 642 CTKSCGKGLRFRSVVCLRGGKEFS---DCPKKSLPDSAGSCNEQSC 684
C+ +CG G++ R V CL G+ + +C + P + +CN+ C
Sbjct: 715 CSATCGVGIQTRDVYCLHPGETPAPPEEC-RDEKPHALQACNQFDC 759
Score = 126 bits (305), Expect = 6e-28
Identities = 81/256 (31%), Positives = 117/256 (45%), Gaps = 22/256 (8%)
Query: 323 PLPTQR---YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQ 378
PLP Y W + F+ C+ATC GG Q C + + V++ LCD +P A +Q
Sbjct: 637 PLPEDSETTYDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQTVNDSLCDMVHRPPAMSQ 696
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKP 438
CNT+ CPP+W G+W CS CG G ++R+V C + P+ +EC D KP
Sbjct: 697 ACNTEPCPPRWHVGSWGPCSATCGV-GIQTRDVYC--LHPGETPA--PPEECRD---EKP 748
Query: 439 ALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSEEKP 497
++CN P W I W+ C + CG G Q R+V C Q +G LSD+ C K
Sbjct: 749 HALQACNQFDCPPGWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGSFLNLSDELCQGPKA 808
Query: 498 LDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQC---VTKDYRV-VNSSFCSYHP 552
+ C C V +W+ C +C ++ R C K R+ ++ C P
Sbjct: 809 SSHKSCARTDCP-PHLAVGDWSKCSVSCGVGIQRRKQVCQRLAAKGRRIPLSEMMCRDLP 867
Query: 553 TPALEEPCDKDKLPAC 568
L C ++P C
Sbjct: 868 GLPLVRSC---QMPEC 880
Score = 120 bits (290), Expect = 4e-26
Identities = 83/256 (32%), Positives = 111/256 (43%), Gaps = 19/256 (7%)
Query: 376 TNQTCNTQACPPQ---WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFD 432
TN T PPQ W PGNWS CS CG G R + +C ++ NG V + C
Sbjct: 1412 TNSNDPTGEPPPQEPFWEPGNWSHCSATCGHLGARIQRPQC--VMANG--QEVSEALCDH 1467
Query: 433 LLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDE 491
L P A +E CN+ WF S W C CG G +RQV C + K NG + V+S
Sbjct: 1468 LQKPL-AGFEPCNIRDCPARWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRS 1526
Query: 492 CS-EEKPLDRQPCELEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSY 550
C+ +++PL R+PC PC V W C R+ Q T + S C
Sbjct: 1527 CAPKDRPLGRKPCFGHPC--VQW--EPGNRCPGRCMGRAVRMQQRHTACQHNSSDSNCDD 1582
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSN 610
P L C AC V W+ W C+ CG G ++R+V C S V +
Sbjct: 1583 RKRPTLRRNCTSG---ACDVCWHTGPWKPCTAACGRGFQSRKVDC--IHTRSCKPVAKRH 1637
Query: 611 CPKEEKYNDSKPCEVP 626
C +++K + C P
Sbjct: 1638 CVQKKKPISWRHCLGP 1653
Score = 107 bits (258), Expect = 3e-22
Identities = 84/295 (28%), Positives = 124/295 (42%), Gaps = 34/295 (11%)
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCEKIIT-NGLPSVVDDKECFDLLGP--KPALYES 443
P ++P WS CS CG G + REV+C ++T + + ++EC P +P L E+
Sbjct: 566 PTFIPEPWSACSTTCGP-GVQVREVKCRVLLTFTQTETELPEEECEGPKLPTERPCLLEA 624
Query: 444 CN-------VDAACPT-------WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSD 489
C+ +D P W + + PC C G Q VC + ++D
Sbjct: 625 CDESPASRELDIPLPEDSETTYDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQ--TVND 682
Query: 490 DECS--EEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSS 546
C P Q C EPC W V W C TC +++R C+
Sbjct: 683 SLCDMVHRPPAMSQACNTEPCPP-RWHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPE 741
Query: 547 FCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKF--DGASVM 604
C AL+ C++ C W+ +W +CS CG G + RRV C + DG S +
Sbjct: 742 ECRDEKPHALQA-CNQFD---CPPGWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDG-SFL 796
Query: 605 KVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
+ D C + K + K C + CP WS+C+ SCG G++ R VC R
Sbjct: 797 NLSDELC-QGPKASSHKSCARTD--CPPHLAVGDWSKCSVSCGVGIQRRKQVCQR 848
Score = 100 bits (240), Expect = 5e-20
Identities = 81/272 (29%), Positives = 111/272 (40%), Gaps = 28/272 (10%)
Query: 325 PTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNT 382
P Q W GN+S CSATCG G + + C E V E LCD KP A + CN
Sbjct: 1422 PPQEPFWEPGNWSHCSATCGHLGARIQRPQCVMANGQE-VSEALCDHLQKPLAGFEPCNI 1480
Query: 383 QACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL---LGPKPA 439
+ CP +W WS+CS CG +G SR+V C++ NG VV + C LG KP
Sbjct: 1481 RDCPARWFTSVWSQCSVSCG-EGYHSRQVTCKRTKANGTVQVVSPRSCAPKDRPLGRKPC 1539
Query: 440 LYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK-PL 498
C W+P ++ C R V Q++ + SD C + K P
Sbjct: 1540 FGHPC-----------VQWEPGNR-CPGRCMGRAVRMQQRHTACQHNSSDSNCDDRKRPT 1587
Query: 499 DRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFCSYHPTP-- 554
R+ C C+ V W W C C +SR C+ T+ + V C P
Sbjct: 1588 LRRNCTSGACD-VCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCKPVAKRHCVQKKKPIS 1646
Query: 555 ---ALEEPCDKDKLPACQVQWYATQWSKCSVE 583
L CD+D + + CS++
Sbjct: 1647 WRHCLGPSCDRDCTDTTHYCMFVKHLNLCSLD 1678
Score = 72.9 bits (171), Expect = 1e-11
Identities = 67/246 (27%), Positives = 97/246 (39%), Gaps = 26/246 (10%)
Query: 451 PTWFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECSEEKPLDR-QPCELEPC 508
P W W C CG G + ++ C N ++ D +KPL +PC + C
Sbjct: 1426 PFWEPGNWSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHL--QKPLAGFEPCNIRDC 1483
Query: 509 EGVDWMVSEWTGCD-TCLATVRSRVAQCV-TK---DYRVVNSSFCSYHPTPALEEPCDKD 563
W S W+ C +C SR C TK +VV+ C+ P +PC
Sbjct: 1484 PA-RWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRSCAPKDRPLGRKPCFGH 1542
Query: 564 KLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C VQW ++C C +G+ R + A DSNC ++ + C
Sbjct: 1543 P---C-VQW--EPGNRCPGRC-MGRAVRMQ---QRHTACQHNSSDSNCDDRKRPTLRRNC 1592
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL--RGGKEFS--DCPKKSLPDSAGSC 679
C W+ PW CT +CG+G + R V C+ R K + C +K P S C
Sbjct: 1593 T--SGACDVCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCKPVAKRHCVQKKKPISWRHC 1650
Query: 680 NEQSCE 685
SC+
Sbjct: 1651 LGPSCD 1656
>BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein.
Length = 1682
Score = 254 bits (621), Expect = 3e-66
Identities = 193/706 (27%), Positives = 306/706 (43%), Gaps = 104/706 (14%)
Query: 54 DVTPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQ 113
D + CSRTCGGG + R CL G N C G + +Y +C DCP ++ DFRA+QC+
Sbjct: 83 DWSDCSRTCGGGASYSLRRCLT-GRN----CEGQNIRYKTCSNHDCPPDAEDFRAQQCSA 137
Query: 114 YNNVTFRGKKYRWVP-YLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDG 172
YN+V ++G Y W+P Y + PC L C G KV+DGTRCN DS D+C+ G
Sbjct: 138 YNDVQYQGHYYEWLPRYNDPAAPCALKCHAQGQNLVVELAPKVLDGTRCNTDSLDMCISG 197
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQ-DLRKGYNDILLIPEGATTI 231
+CQ VGCD LGSNAKED C C G+G C + + K +++ +P G+ ++
Sbjct: 198 ICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSV 257
Query: 232 YITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSL 291
IT P++ ++ ++ G+ G++ + P + ++R + T +
Sbjct: 258 RITVKGPAHLFIESKTLQGS---KGEHSFNSPGVFVVENTTVEFQRGSERQT----FKIP 310
Query: 292 GPI-NEPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSR 350
GP+ + ++ + ++ V++ + PI + W +F C+ TCGGG Q
Sbjct: 311 GPLMADFIFKTRYTAAKDSVVQFFFYQPIS--------HQWRQTDFFPCTVTCGGGYQLN 362
Query: 351 DVTCRSREELEVVDEGLC---DDGLKPATN-QTCNTQACP-----------------PQW 389
C VV + C + +KP + C+ CP P+W
Sbjct: 363 SAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSDGFKEIMPYDHFQPLPRW 422
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
W+ CS CG G + R C + +G V++ +C + PKP + ++CN+
Sbjct: 423 EHNPWTACSVSCG-GGIQRRSFVCVEESMHGEILQVEEWKC--MYAPKPKVMQTCNL-FD 478
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKN-------NGRINVLSDDEC---------S 493
CP W W C CG G + R V+C N ++ + +EC
Sbjct: 479 CPKWIAMEWSQCTVTCGRGLRYRVVLCINHRGEHVGGCNPQLKLHIKEECVIPIPCYKPK 538
Query: 494 EEKPLD------RQPCELE----PCEGVDWMVSEWTGCD-TC-----LATVRSRVAQCVT 537
E+ P++ +Q ELE E ++ W+ C TC + V+ RV T
Sbjct: 539 EKSPVEAKLPWLKQAQELEETRIATEEPTFIPEPWSACSTTCGPGVQVREVKCRVLLTFT 598
Query: 538 KDYRVVNSSFCS--YHPT--PALEEPCDKD--------KLP---ACQVQWYATQWSKCSV 582
+ + C PT P L E CD+ LP W ++ C+
Sbjct: 599 QTETELPEEECEGPKLPTERPCLLEACDESPASRELDIPLPEDSETTYDWEYAGFTPCTA 658
Query: 583 ECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND-SKPCEVPEEKCPSKWYAAPWSE 641
C G + C + V+DS C + S+ C E CP +W+ W
Sbjct: 659 TCLGGHQEAIAVCLHIQ--TQQTVNDSLCDMVHRPPAMSQACNT--EPCPPRWHVGSWGP 714
Query: 642 CTKSCGKGLRFRSVVCLRGGKEFS---DCPKKSLPDSAGSCNEQSC 684
C+ +CG G++ R V CL G+ + +C + P + +CN+ C
Sbjct: 715 CSATCGVGIQTRDVYCLHPGETPAPPEEC-RDEKPHALQACNQFDC 759
Score = 126 bits (304), Expect = 9e-28
Identities = 73/219 (33%), Positives = 104/219 (47%), Gaps = 15/219 (6%)
Query: 323 PLPTQR---YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQ 378
PLP Y W + F+ C+ATC GG Q C + + V++ LCD +P A +Q
Sbjct: 637 PLPEDSETTYDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQTVNDSLCDMVHRPPAMSQ 696
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKP 438
CNT+ CPP+W G+W CS CG G ++R+V C + P+ +EC D KP
Sbjct: 697 ACNTEPCPPRWHVGSWGPCSATCGV-GIQTRDVYC--LHPGETPA--PPEECRD---EKP 748
Query: 439 ALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSEEKP 497
++CN P W I W+ C + CG G Q R+V C Q +G LSD+ C K
Sbjct: 749 HALQACNQFDCPPGWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGSFLNLSDELCQGPKA 808
Query: 498 LDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQC 535
+ C C V +W+ C +C ++ R C
Sbjct: 809 SSHKSCARTDCP-PHLAVGDWSKCSVSCGVGIQRRKQVC 846
Score = 120 bits (289), Expect = 6e-26
Identities = 83/256 (32%), Positives = 111/256 (43%), Gaps = 19/256 (7%)
Query: 376 TNQTCNTQACPPQ---WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFD 432
TN T PPQ W PGNWS CS CG G R + +C ++ NG V + C
Sbjct: 1412 TNSNDPTGEPPPQEPFWEPGNWSHCSATCGHLGARIQRPQC--VMANG--QEVSEALCDH 1467
Query: 433 LLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDE 491
L P A +E CN+ WF S W C CG G +RQV C + K NG + V+S
Sbjct: 1468 LQKPL-AGFEPCNIRDCPARWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRA 1526
Query: 492 CS-EEKPLDRQPCELEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSY 550
C+ +++PL R+PC PC V W C R+ Q T + S C
Sbjct: 1527 CAPKDRPLGRKPCFGHPC--VQW--EPGNRCPGRCMGRAVRMQQRHTACQHNSSDSNCDD 1582
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSN 610
P L C AC V W+ W C+ CG G ++R+V C S V +
Sbjct: 1583 RKRPTLRRNCTSG---ACDVCWHTGPWKPCTAACGRGFQSRKVDC--IHTRSCKPVAKRH 1637
Query: 611 CPKEEKYNDSKPCEVP 626
C +++K + C P
Sbjct: 1638 CVQKKKPISWRHCLGP 1653
Score = 113 bits (271), Expect = 9e-24
Identities = 91/338 (26%), Positives = 142/338 (42%), Gaps = 43/338 (12%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCR-----SREELEVVDEGLCDDGLK 373
+E+ + T+ +++ +S+CS TCG G+Q R+V CR ++ E E+ +E C+ G K
Sbjct: 556 LEETRIATEEPTFIPEPWSACSTTCGPGVQVREVKCRVLLTFTQTETELPEEE-CE-GPK 613
Query: 374 PATNQTCNTQACP------------PQ-------WVPGNWSRCSKRCGKDGTRSREVRCE 414
T + C +AC P+ W ++ C+ C G + C
Sbjct: 614 LPTERPCLLEACDESPASRELDIPLPEDSETTYDWEYAGFTPCTATC-LGGHQEAIAVCL 672
Query: 415 KIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQV 474
I T V+D C D++ PA+ ++CN + P W + W PC CG G QTR V
Sbjct: 673 HIQTQ---QTVNDSLC-DMVHRPPAMSQACNTEPCPPRWHVGSWGPCSATCGVGIQTRDV 728
Query: 475 VCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVA 533
C +EC +EKP Q C C W + EW C TC ++R
Sbjct: 729 YCLHPGE---TPAPPEECRDEKPHALQACNQFDCP-PGWHIEEWQQCSRTCGGGTQNRRV 784
Query: 534 QC--VTKDYRVVN-SSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKT 590
C + D +N S P + + C + C WSKCSV CGVG +
Sbjct: 785 TCRQLLTDGSFLNLSDELCQGPKASSHKSCARTD---CPPHLAVGDWSKCSVSCGVGIQR 841
Query: 591 RRVFCGKFDG-ASVMKVDDSNCPKEEKYNDSKPCEVPE 627
R+ C + + + + C + + C++PE
Sbjct: 842 RKQVCQRLAAKGRRIPLSEMMCRDLPGFPLVRSCQMPE 879
Score = 107 bits (258), Expect = 3e-22
Identities = 84/295 (28%), Positives = 124/295 (42%), Gaps = 34/295 (11%)
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCEKIIT-NGLPSVVDDKECFDLLGP--KPALYES 443
P ++P WS CS CG G + REV+C ++T + + ++EC P +P L E+
Sbjct: 566 PTFIPEPWSACSTTCGP-GVQVREVKCRVLLTFTQTETELPEEECEGPKLPTERPCLLEA 624
Query: 444 CN-------VDAACPT-------WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSD 489
C+ +D P W + + PC C G Q VC + ++D
Sbjct: 625 CDESPASRELDIPLPEDSETTYDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQ--TVND 682
Query: 490 DECS--EEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSS 546
C P Q C EPC W V W C TC +++R C+
Sbjct: 683 SLCDMVHRPPAMSQACNTEPCPP-RWHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPE 741
Query: 547 FCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKF--DGASVM 604
C AL+ C++ C W+ +W +CS CG G + RRV C + DG S +
Sbjct: 742 ECRDEKPHALQA-CNQFD---CPPGWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDG-SFL 796
Query: 605 KVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
+ D C + K + K C + CP WS+C+ SCG G++ R VC R
Sbjct: 797 NLSDELC-QGPKASSHKSCARTD--CPPHLAVGDWSKCSVSCGVGIQRRKQVCQR 848
Score = 97.5 bits (232), Expect = 5e-19
Identities = 76/244 (31%), Positives = 101/244 (41%), Gaps = 23/244 (9%)
Query: 325 PTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNT 382
P Q W GN+S CSATCG G + + C E V E LCD KP A + CN
Sbjct: 1422 PPQEPFWEPGNWSHCSATCGHLGARIQRPQCVMANGQE-VSEALCDHLQKPLAGFEPCNI 1480
Query: 383 QACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL---LGPKPA 439
+ CP +W WS+CS CG +G SR+V C++ NG VV + C LG KP
Sbjct: 1481 RDCPARWFTSVWSQCSVSCG-EGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPC 1539
Query: 440 LYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK-PL 498
C W+P ++ C R V Q++ + SD C + K P
Sbjct: 1540 FGHPC-----------VQWEPGNR-CPGRCMGRAVRMQQRHTACQHNSSDSNCDDRKRPT 1587
Query: 499 DRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFCSYHPTPAL 556
R+ C C+ V W W C C +SR C+ T+ + V C P
Sbjct: 1588 LRRNCTSGACD-VCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCKPVAKRHCVQKKKPIS 1646
Query: 557 EEPC 560
C
Sbjct: 1647 WRHC 1650
Score = 81.8 bits (193), Expect = 2e-14
Identities = 56/184 (30%), Positives = 78/184 (42%), Gaps = 19/184 (10%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE---LEVVDEGLCDDGLKPATNQTCNTQACPP 387
W +S CS +CG G SR VTC+ + ++VV C +P + C C
Sbjct: 1487 WFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGHPCV- 1545
Query: 388 QWVPGNWSRCSKRCGKDGTR--SREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCN 445
QW PGN RC RC R R C+ N S DD++ +P L +C
Sbjct: 1546 QWEPGN--RCPGRCMGRAVRMQQRHTACQH---NSSDSNCDDRK-------RPTLRRNCT 1593
Query: 446 VDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCEL 505
A W PWKPC CG G Q+R+V C + + V ++KP+ + C
Sbjct: 1594 SGACDVCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCK-PVAKRHCVQKKKPISWRHCLG 1652
Query: 506 EPCE 509
C+
Sbjct: 1653 PSCD 1656
Score = 73.3 bits (172), Expect = 8e-12
Identities = 67/247 (27%), Positives = 98/247 (39%), Gaps = 26/247 (10%)
Query: 451 PTWFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECSEEKPLDR-QPCELEPC 508
P W W C CG G + ++ C N ++ D +KPL +PC + C
Sbjct: 1426 PFWEPGNWSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHL--QKPLAGFEPCNIRDC 1483
Query: 509 EGVDWMVSEWTGCD-TCLATVRSRVAQCV-TK---DYRVVNSSFCSYHPTPALEEPCDKD 563
W S W+ C +C SR C TK +VV+ C+ P +PC
Sbjct: 1484 PA-RWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGH 1542
Query: 564 KLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C VQW ++C C +G+ R + A DSNC ++ + C
Sbjct: 1543 P---C-VQW--EPGNRCPGRC-MGRAVRMQ---QRHTACQHNSSDSNCDDRKRPTLRRNC 1592
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL--RGGKEFS--DCPKKSLPDSAGSC 679
C W+ PW CT +CG+G + R V C+ R K + C +K P S C
Sbjct: 1593 T--SGACDVCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCKPVAKRHCVQKKKPISWRHC 1650
Query: 680 NEQSCEA 686
SC++
Sbjct: 1651 LGPSCDS 1657
>AF237652-1|AAK15041.1| 766|Homo sapiens a disintegrin-like and
metalloprotease domain with thrombospondin type I motifs
protein.
Length = 766
Score = 252 bits (618), Expect = 8e-66
Identities = 193/706 (27%), Positives = 305/706 (43%), Gaps = 104/706 (14%)
Query: 54 DVTPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQ 113
D + CSRTCGGG + R CL G N C G + +Y +C DCP ++ DFRA+QC+
Sbjct: 83 DWSDCSRTCGGGASYSLRRCLT-GRN----CEGQNIRYKTCSNHDCPPDAEDFRAQQCSA 137
Query: 114 YNNVTFRGKKYRWVP-YLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDG 172
YN+V ++G Y W+P Y + PC L C G KV+DGTRCN DS D+C+ G
Sbjct: 138 YNDVQYQGHYYEWLPRYNDPAAPCALKCHAQGQNLVVELAPKVLDGTRCNTDSLDMCISG 197
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQ-DLRKGYNDILLIPEGATTI 231
+CQ VGCD LGSNAKED C C G+G C + + K +++ +P G+ ++
Sbjct: 198 ICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSV 257
Query: 232 YITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSL 291
IT P + ++ ++ G+ G++ + P + ++R + T +
Sbjct: 258 RITVKGPVHLFIESKTLQGS---KGEHSFNSPGVFVVENTTVEFQRGSERQT----FKIP 310
Query: 292 GPI-NEPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSR 350
GP+ + ++ + ++ V++ + PI + W +F C+ TCGGG Q
Sbjct: 311 GPLMADFIFKTRYTAAKDSVVQFFFYQPIS--------HQWRQTDFFPCTVTCGGGYQLN 362
Query: 351 DVTCRSREELEVVDEGLC---DDGLKPATN-QTCNTQACP-----------------PQW 389
C VV + C + +KP + C+ CP P+W
Sbjct: 363 SAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSDGFKEIMPYDHFQPLPRW 422
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
W+ CS CG G + R C + +G V++ +C + PKP + ++CN+
Sbjct: 423 EHNPWTACSVSCG-GGIQRRSFVCVEESMHGEILQVEEWKC--MYAPKPKVMQTCNL-FD 478
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKN-------NGRINVLSDDEC---------S 493
CP W W C CG G + R V+C N ++ + +EC
Sbjct: 479 CPKWIAMEWSQCTVTCGRGLRYRVVLCINHRGEHVGGCNPQLKLHIKEECVIPIPCYKPK 538
Query: 494 EEKPLD------RQPCELE----PCEGVDWMVSEWTGCD-TC-----LATVRSRVAQCVT 537
E+ P++ +Q ELE E ++ W+ C TC + V+ RV T
Sbjct: 539 EKSPVEAKLPWLKQAQELEETRIATEEPTFIPEPWSACSTTCGPGVQVREVKCRVLLTFT 598
Query: 538 KDYRVVNSSFCS--YHPT--PALEEPCDKD--------KLP---ACQVQWYATQWSKCSV 582
+ + C PT P L E CD+ LP W ++ C+
Sbjct: 599 QTETELPEEECEGPKLPTERPCLLEACDESPASRELDIPLPEDSETTYDWEYAGFTPCTA 658
Query: 583 ECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND-SKPCEVPEEKCPSKWYAAPWSE 641
C G + C + V+DS C + S+ C E CP +W+ W
Sbjct: 659 TCLGGHQEAIAVCLHIQ--TQQTVNDSLCDMVHRPPAMSQACNT--EPCPPRWHVGSWGP 714
Query: 642 CTKSCGKGLRFRSVVCLRGGKEFS---DCPKKSLPDSAGSCNEQSC 684
C+ +CG G++ R V CL G+ + +C + P + +CN+ C
Sbjct: 715 CSATCGVGIQTRDVYCLHPGETPAPPEEC-RDEKPHALQACNQFDC 759
Score = 86.2 bits (204), Expect = 1e-15
Identities = 49/137 (35%), Positives = 69/137 (50%), Gaps = 12/137 (8%)
Query: 323 PLPTQR---YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQ 378
PLP Y W + F+ C+ATC GG Q C + + V++ LCD +P A +Q
Sbjct: 637 PLPEDSETTYDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQTVNDSLCDMVHRPPAMSQ 696
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKP 438
CNT+ CPP+W G+W CS CG G ++R+V C + P+ +EC D KP
Sbjct: 697 ACNTEPCPPRWHVGSWGPCSATCGV-GIQTRDVYC--LHPGETPA--PPEECRD---EKP 748
Query: 439 ALYESCNVDAACPTWFI 455
++CN P W I
Sbjct: 749 HALQACNQFDCPPGWHI 765
Score = 81.4 bits (192), Expect = 3e-14
Identities = 59/208 (28%), Positives = 89/208 (42%), Gaps = 32/208 (15%)
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVC--YQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
PT+ PW C CG G Q R+V C L ++EC K +PC LE C
Sbjct: 566 PTFIPEPWSACSTTCGPGVQVREVKCRVLLTFTQTETELPEEECEGPKLPTERPCLLEAC 625
Query: 509 EG------------------VDWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFC 548
+ DW + +T C TCL + +A C+ + + VN S C
Sbjct: 626 DESPASRELDIPLPEDSETTYDWEYAGFTPCTATCLGGHQEAIAVCLHIQTQQTVNDSLC 685
Query: 549 SY-HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVD 607
H PA+ + C+ + C +W+ W CS CGVG +TR V+C G + +
Sbjct: 686 DMVHRPPAMSQACNTEP---CPPRWHVGSWGPCSATCGVGIQTRDVYC-LHPGETPAPPE 741
Query: 608 DSNCPKEEKYNDSKPCEVPEEKCPSKWY 635
+ C ++EK + + C + CP W+
Sbjct: 742 E--C-RDEKPHALQACN--QFDCPPGWH 764
>AB002364-1|BAA20821.1| 1201|Homo sapiens KIAA0366 protein.
Length = 1201
Score = 252 bits (617), Expect = 1e-65
Identities = 155/473 (32%), Positives = 220/473 (46%), Gaps = 42/473 (8%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG GV + R C P NG C G + +Y C T++C ++ DFRA+QC Q N+
Sbjct: 559 CSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNS 618
Query: 117 -VTFRGKKYRWVPYLKVS--KPCELTCM--QHGDRFYYRHKEKVIDGTRCN-DDSFDVCV 170
++ K+ W+PY K C L C + GD Y K+ V DGT C+ D + +CV
Sbjct: 619 HFEYQNTKHHWLPYEHPDPKKRCHLYCQSKETGDVAYM--KQLVHDGTHCSYKDPYSICV 676
Query: 171 DGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATT 230
G C VGCD +GSN EDKC C G+ +C T K + GY + IP GA
Sbjct: 677 RGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLGYLKMFDIPPGARH 736
Query: 231 IYITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLR 289
+ I E E S + LA++++ G Y LNG R+ G W+Y + L
Sbjct: 737 VLIQEDEASPHILAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDD----IESLH 792
Query: 290 SLGPINEPLYLSLLLIDENVGVEYEYSLPIEKAPLPT-----------QRYSWVHGNFSS 338
+ GP+++P+ + ++ + + Y I + +PT + W ++S
Sbjct: 793 TDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQ 852
Query: 339 CSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQACP-PQWVPGNWSR 396
S CGGG Q CR + + ++V C+ KP + CN Q C P WV W
Sbjct: 853 VSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPLWVAEEWEH 912
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFI 455
C+K CG G + R VRC + + +G V K C +G +P CN CP W
Sbjct: 913 CTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYC---MGDRPESRRPCN-RVPCPAQWKT 968
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
PW C CG G + RQV+C + D C EKP + C+L PC
Sbjct: 969 GPWSECSVTCGEGTEVRQVLC----------RAGDHCDGEKPESVRACQLPPC 1011
Score = 79.0 bits (186), Expect = 2e-13
Identities = 50/177 (28%), Positives = 80/177 (45%), Gaps = 11/177 (6%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVD 512
W + W K CG G Q + C +K++ ++ S E +++ R+ C ++ C
Sbjct: 845 WALKSWSQVSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPL 904
Query: 513 WMVSEWTGC-DTCLAT-VRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDKLP 566
W+ EW C TC ++ + R +C+ R V+S +C P PC +++P
Sbjct: 905 WVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYC-MGDRPESRRPC--NRVP 961
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C QW WS+CSV CG G + R+V C D K + + ND +PC
Sbjct: 962 -CPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCND-EPC 1016
Score = 76.6 bits (180), Expect = 9e-13
Identities = 56/190 (29%), Positives = 78/190 (41%), Gaps = 12/190 (6%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV- 446
+W +WS+ SK CG G + + C + N +V C PKP + CN+
Sbjct: 844 EWALKSWSQVSKPCG-GGFQYTKYGCRRKSDN---KMVHRSFCEANKKPKP-IRRMCNIQ 898
Query: 447 DAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKN-NGRINVLSDDECSEEKPLDRQPCE 504
+ P W W+ C K CGS G Q R V C Q +G + C ++P R+PC
Sbjct: 899 ECTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESRRPCN 958
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDY--RVVNSSFCSYHPTPALEEPCD 561
PC W W+ C TC R C D+ S + P +EPC
Sbjct: 959 RVPCPA-QWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCNDEPCL 1017
Query: 562 KDKLPACQVQ 571
DK CQ++
Sbjct: 1018 GDKSIFCQME 1027
Score = 73.3 bits (172), Expect = 8e-12
Identities = 53/193 (27%), Positives = 84/193 (43%), Gaps = 16/193 (8%)
Query: 506 EPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCDK 562
E + +W + W+ C + C K D ++V+ SFC + P + C+
Sbjct: 838 EELDTFEWALKSWSQVSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNI 897
Query: 563 DKLPACQVQWYATQWSKCSVECGV-GKKTRRVFCGK--FDGASVMKVDDSNCPKEEKYND 619
+ W A +W C+ CG G + R V C + DG + V C ++
Sbjct: 898 QE--CTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTN-RSVHSKYC-MGDRPES 953
Query: 620 SKPCE-VPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGS 678
+PC VP CP++W PWSEC+ +CG+G R V+C G + P+
Sbjct: 954 RRPCNRVP---CPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPP 1010
Query: 679 CNEQSCEALGEGS 691
CN++ C LG+ S
Sbjct: 1011 CNDEPC--LGDKS 1021
>AJ003125-1|CAA05880.1| 1211|Homo sapiens procollagen I N-proteinase
protein.
Length = 1211
Score = 252 bits (616), Expect = 1e-65
Identities = 151/469 (32%), Positives = 227/469 (48%), Gaps = 31/469 (6%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG GV + R C P NG C+G + C QDCP++ DFR EQC Q++
Sbjct: 573 CSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYDFQLCSRQDCPDSLADFREEQCRQWDL 632
Query: 117 VTFRGK-KYRWVPY--LKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVDG 172
G ++ W+P+ + C L C K V DGTRC+ D+F +CV G
Sbjct: 633 YFEHGDAQHHWLPHEHRDAKERCHLYCESRETGEVVSMKRMVHDGTRCSYKDAFSLCVRG 692
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIY 232
C+ VGCD ++GS+ +EDKC C G+ +C K + GY + IP GA +
Sbjct: 693 DCRKVGCDGVIGSSKQEDKCGVCGGDNSHCKVVKGTFTRSPKKHGYIKMFEIPAGARHLL 752
Query: 233 ITEIEPSNNYLALRS-KNGTYYLNGDYHIDFPRSMTIA-GALWNYERNQQGITAPDKLRS 290
I E++ ++++LA+++ + G + LN + +D IA G W Y R++ G + L++
Sbjct: 753 IQEVDATSHHLAVKNLETGKFILNEENDVDASSKTFIAMGVEWEY-RDEDG---RETLQT 808
Query: 291 LGPINEPLYLSLLLI-DENVGVEYEYSLPIEKAPLPTQR--------YSWVHGNFSSCSA 341
+GP++ + + ++ + D V + Y+Y + + + Y W +S CS
Sbjct: 809 MGPLHGTITVLVIPVGDTRVSLTYKYMIHEDSLNVDDNNVLEEDSVVYEWALKKWSPCSK 868
Query: 342 TCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQAC-PPQWVPGNWSRCSK 399
CGGG Q CR R + ++V G C KP A + CN Q C P WV G W CS+
Sbjct: 869 PCGGGSQFTKYGCRRRLDHKMVHRGFCAALSKPKAIRRACNPQECSQPVWVTGEWEPCSQ 928
Query: 400 RCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWK 459
CG+ G + R VRC + + + V K C D +P +C+ + W PW
Sbjct: 929 TCGRTGMQVRSVRCIQPLHDNTTRSVHAKHCND---ARPESRRACSRELCPGRWRAGPWS 985
Query: 460 PCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
C CG+G Q R V C ++ S C EE+P + C L PC
Sbjct: 986 QCSVTCGNGTQERPVPCRTADD------SFGICQEERPETARTCRLGPC 1028
Score = 78.6 bits (185), Expect = 2e-13
Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 11/178 (6%)
Query: 512 DWMVSEWTGCDT-CLATVRSRVAQCVTK-DYRVVNSSFCSYHPTP-ALEEPCDKDKLPAC 568
+W + +W+ C C + C + D+++V+ FC+ P A+ C+ +
Sbjct: 857 EWALKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVHRGFCAALSKPKAIRRACNPQE--CS 914
Query: 569 QVQWYATQWSKCSVECG-VGKKTRRVFCGK-FDGASVMKVDDSNCPKEEKYNDSKPCEVP 626
Q W +W CS CG G + R V C + + V +C + + + C
Sbjct: 915 QPVWVTGEWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHC-NDARPESRRACS-- 971
Query: 627 EEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSC 684
E CP +W A PWS+C+ +CG G + R V C F C ++ P++A +C C
Sbjct: 972 RELCPGRWRAGPWSQCSVTCGNGTQERPVPCRTADDSFGIC-QEERPETARTCRLGPC 1028
Score = 71.3 bits (167), Expect = 3e-11
Identities = 42/155 (27%), Positives = 63/155 (40%), Gaps = 2/155 (1%)
Query: 447 DAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELE 506
D+ W + W PC K CG G Q + C ++ + ++ + R+ C +
Sbjct: 852 DSVVYEWALKKWSPCSKPCGGGSQFTKYGCRRRLDHKMVHRGFCAALSKPKAIRRACNPQ 911
Query: 507 PCEGVDWMVSEWTGC-DTCLAT-VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDK 564
C W+ EW C TC T ++ R +C+ + S + H A E
Sbjct: 912 ECSQPVWVTGEWEPCSQTCGRTGMQVRSVRCIQPLHDNTTRSVHAKHCNDARPESRRACS 971
Query: 565 LPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFD 599
C +W A WS+CSV CG G + R V C D
Sbjct: 972 RELCPGRWRAGPWSQCSVTCGNGTQERPVPCRTAD 1006
Score = 35.5 bits (78), Expect = 2.1
Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 13/69 (18%)
Query: 629 KCPSKWYA-APWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSDCPKKSLPDS 675
K W A +P+ C+++CG G++FR+ C GG+ +F C ++ PDS
Sbjct: 559 KRDGSWGAWSPFGSCSRTCGTGVKFRTRQCDNPHPANGGRTCSGLAYDFQLCSRQDCPDS 618
Query: 676 AGSCNEQSC 684
E+ C
Sbjct: 619 LADFREEQC 627
>AK131414-1|BAD18561.1| 493|Homo sapiens protein ( Homo sapiens
cDNA FLJ16524 fis, clone OCBBF2003327, moderately
similar to ADAM-TS 6 precursor (EC 3.4.24.-). ).
Length = 493
Score = 250 bits (613), Expect = 3e-65
Identities = 133/380 (35%), Positives = 190/380 (50%), Gaps = 13/380 (3%)
Query: 131 KVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQPVGCDMMLGSNAKED 190
+ + C LTC+ G FY V+DGT C D+ D+CV G C+ VGCD +LGS+ +ED
Sbjct: 121 RTGEACSLTCLAEGFNFYTERAAAVVDGTPCRPDTVDICVSGECKHVGCDRVLGSDLRED 180
Query: 191 KCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNG 250
KCR C G+G C T + + + GY D++ IP+G+ I+I ++ S N+LAL+
Sbjct: 181 KCRVCGGDGSACETIEGVFSPASPGAGYEDVVWIPKGSVHIFIQDLNLSLNHLALKGDQE 240
Query: 251 TYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVG 310
+ L G P + +AG + +QG L +LGPIN L + +L E
Sbjct: 241 SLLLEGLPGTPQPHRLPLAGTTFQL---RQGPDQVQSLEALGPINASLIVMVLARTELPA 297
Query: 311 VEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDD 370
+ Y ++ PI + LP YSW + ++ CSA C GG Q + V CR++ + V C
Sbjct: 298 LRYRFNAPIARDSLPP--YSWHYAPWTRCSAQCAGGSQVQAVECRNQLDGSAVAPHYCSA 355
Query: 371 GLK-PATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKE 429
K P + CNT+ CPP WV GNWS CS+ C G RSR V C++ ++ +DD
Sbjct: 356 HSKLPKRQRACNTEPCPPDWVVGNWSLCSRSCDA-GVRSRSVVCQRRVSAAEEKALDDSA 414
Query: 430 CFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSD 489
C P+P + E+C+ P W W C CG G + R V+C K+ L
Sbjct: 415 CPQ---PRPPVLEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLC--KSADHRATLPP 469
Query: 490 DECS-EEKPLDRQPCELEPC 508
CS KP C L C
Sbjct: 470 AHCSPAAKPPATMRCNLRRC 489
Score = 91.5 bits (217), Expect = 3e-17
Identities = 57/180 (31%), Positives = 80/180 (44%), Gaps = 14/180 (7%)
Query: 513 WMVSEWTGCDT-CLATVRSRVAQCVTK-DYRVVNSSFCSYHPT-PALEEPCDKDKLPACQ 569
W + WT C C + + +C + D V +CS H P + C+ + C
Sbjct: 316 WHYAPWTRCSAQCAGGSQVQAVECRNQLDGSAVAPHYCSAHSKLPKRQRACNTEP---CP 372
Query: 570 VQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMK-VDDSNCPKEEKYNDSKPCEVPEE 628
W WS CS C G ++R V C + A+ K +DDS CP + + + C P
Sbjct: 373 PDWVVGNWSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACP-QPRPPVLEACHGPT- 430
Query: 629 KCPSKWYAAPWSECTKSCGKGLRFRSVVCL----RGGKEFSDCPKKSLPDSAGSCNEQSC 684
CP +W A WSECT SCG GLR R V+C R + C + P + CN + C
Sbjct: 431 -CPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRC 489
Score = 50.0 bits (114), Expect = 9e-05
Identities = 20/63 (31%), Positives = 30/63 (47%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQA 384
PT W ++S C+ +CG G++ R V C+S + + C KP CN +
Sbjct: 429 PTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRR 488
Query: 385 CPP 387
CPP
Sbjct: 489 CPP 491
Score = 35.1 bits (77), Expect = 2.7
Identities = 18/59 (30%), Positives = 27/59 (45%), Gaps = 5/59 (8%)
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVCLR--GGKEFSD--CPKKS-LPDSAGSCNEQSC 684
P W+ APW+ C+ C G + ++V C G + C S LP +CN + C
Sbjct: 313 PYSWHYAPWTRCSAQCAGGSQVQAVECRNQLDGSAVAPHYCSAHSKLPKRQRACNTEPC 371
>AF366351-1|AAL79814.1| 1159|Homo sapiens ADAMTS14 protein.
Length = 1159
Score = 245 bits (600), Expect = 1e-63
Identities = 170/538 (31%), Positives = 244/538 (45%), Gaps = 51/538 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP--NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN 115
CSR+CGGGV S+ R C P G P C G +Y C +++CP DFRA+QCA+ N
Sbjct: 500 CSRSCGGGVRSRSRSCNNPSPAYGGRP-CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRN 558
Query: 116 NV-TFRGKKYRWVPYLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVD 171
+ + K+ WVPY ++ CEL C + V DGTRC+ D + VC
Sbjct: 559 SYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCAR 618
Query: 172 GVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTI 231
G C PVGCD +GS +DKC C G+ +C T K + + G ++ IP GA I
Sbjct: 619 GECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHI 678
Query: 232 YITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRS 290
I +E S + + ++++ G++ LN R+ T G W A + L++
Sbjct: 679 QIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVED----AKESLKT 734
Query: 291 LGPINEPLYLSLLLIDE---NVGVEYEYSLPIEKAPL---------PTQRYSWVHGNFSS 338
GP+ E + + L E + Y+Y + + PL Y W +++
Sbjct: 735 SGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAP 794
Query: 339 CSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQAC-PPQWVPGNWSR 396
CS CGGGIQ CR R + +V LCD +P + CN C P WV W
Sbjct: 795 CSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGA 854
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFI 455
CS+ CGK G ++R ++C ++NG V+ K C G +P C + CP W +
Sbjct: 855 CSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKAC---AGDRPEARRPC-LRVPCPAQWRL 910
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
W C CG G Q RQVVC R N S C ++P Q C L C G
Sbjct: 911 GAWSQCSATCGEGIQQRQVVC------RTNANSLGHCEGDRPDTVQVCSLPACGG----- 959
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE--EPCDKDKLPACQVQ 571
+ +TVR+ V + T + + V S HP + EPC D+ CQ++
Sbjct: 960 ------NHQNSTVRADVWELGTPEGQWVPQSE-PLHPINKISSTEPCTGDRSVFCQME 1010
Score = 81.8 bits (193), Expect = 2e-14
Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 20/240 (8%)
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCD 561
LE + +W + W C C ++ C + D+ +V C + P + C+
Sbjct: 779 LEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCN 838
Query: 562 KDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDS 620
+ P Q W +W CS CG +G +TR + C KV + ++
Sbjct: 839 QH--PCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEAR 896
Query: 621 KPC-EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSC 679
+PC VP CP++W WS+C+ +CG+G++ R VVC C + PD+ C
Sbjct: 897 RPCLRVP---CPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHC-EGDRPDTVQVC 952
Query: 680 NEQSCEALGEGSGYFTSLDLESTFPEIGSGTEIGKGFLKKSRYLTSINNTTSIKDCIVDQ 739
+ +C G + + + E+ GT G+ ++ +S L IN +S + C D+
Sbjct: 953 SLPAC------GGNHQNSTVRADVWEL--GTPEGQ-WVPQSEPLHPINKISSTEPCTGDR 1003
Score = 74.9 bits (176), Expect = 3e-12
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEPCEGV 511
W + W PC K CG G Q + C ++ + + D KP+ R+ C PC
Sbjct: 787 WALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRR-CNQHPCSQP 845
Query: 512 DWMVSEWTGCD-TC-LATVRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
W+ EW C +C V++R QC+ ++V+ + C+ P PC ++
Sbjct: 846 VWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACA-GDRPEARRPC--LRV 902
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFC 595
P C QW WS+CS CG G + R+V C
Sbjct: 903 P-CPAQWRLGAWSQCSATCGEGIQQRQVVC 931
Score = 38.7 bits (86), Expect = 0.22
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQ 388
SW F SCS +CGGG++SR +C + C L P Q CN++ CP
Sbjct: 493 SWT--KFGSCSRSCGGGVRSRSRSCNNPS--PAYGGRPC---LGPMFEYQVCNSEECPGT 545
Query: 389 WVPGNWSRCSKR 400
+ +C+KR
Sbjct: 546 YEDFRAQQCAKR 557
>AF358666-1|AAL40229.1| 1223|Homo sapiens a disintegrin-like and
metalloprotease with thrombospondin type 1 motif 14 prec
protein.
Length = 1223
Score = 245 bits (600), Expect = 1e-63
Identities = 170/538 (31%), Positives = 244/538 (45%), Gaps = 51/538 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP--NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN 115
CSR+CGGGV S+ R C P G P C G +Y C +++CP DFRA+QCA+ N
Sbjct: 564 CSRSCGGGVRSRSRSCNNPSPAYGGRP-CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRN 622
Query: 116 NV-TFRGKKYRWVPYLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVD 171
+ + K+ WVPY ++ CEL C + V DGTRC+ D + VC
Sbjct: 623 SYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCAR 682
Query: 172 GVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTI 231
G C PVGCD +GS +DKC C G+ +C T K + + G ++ IP GA I
Sbjct: 683 GECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHI 742
Query: 232 YITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRS 290
I +E S + + ++++ G++ LN R+ T G W A + L++
Sbjct: 743 QIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVED----AKESLKT 798
Query: 291 LGPINEPLYLSLLLIDE---NVGVEYEYSLPIEKAPL---------PTQRYSWVHGNFSS 338
GP+ E + + L E + Y+Y + + PL Y W +++
Sbjct: 799 SGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAP 858
Query: 339 CSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQAC-PPQWVPGNWSR 396
CS CGGGIQ CR R + +V LCD +P + CN C P WV W
Sbjct: 859 CSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGA 918
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFI 455
CS+ CGK G ++R ++C ++NG V+ K C G +P C + CP W +
Sbjct: 919 CSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKAC---AGDRPEARRPC-LRVPCPAQWRL 974
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
W C CG G Q RQVVC R N S C ++P Q C L C G
Sbjct: 975 GAWSQCSATCGEGIQQRQVVC------RTNANSLGHCEGDRPDTVQVCSLPACGG----- 1023
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE--EPCDKDKLPACQVQ 571
+ +TVR+ V + T + + V S HP + EPC D+ CQ++
Sbjct: 1024 ------NHQNSTVRADVWELGTPEGQWVPQSE-PLHPINKISSTEPCTGDRSVFCQME 1074
Score = 81.8 bits (193), Expect = 2e-14
Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 20/240 (8%)
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCD 561
LE + +W + W C C ++ C + D+ +V C + P + C+
Sbjct: 843 LEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCN 902
Query: 562 KDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDS 620
+ P Q W +W CS CG +G +TR + C KV + ++
Sbjct: 903 QH--PCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEAR 960
Query: 621 KPC-EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSC 679
+PC VP CP++W WS+C+ +CG+G++ R VVC C + PD+ C
Sbjct: 961 RPCLRVP---CPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHC-EGDRPDTVQVC 1016
Query: 680 NEQSCEALGEGSGYFTSLDLESTFPEIGSGTEIGKGFLKKSRYLTSINNTTSIKDCIVDQ 739
+ +C G + + + E+ GT G+ ++ +S L IN +S + C D+
Sbjct: 1017 SLPAC------GGNHQNSTVRADVWEL--GTPEGQ-WVPQSEPLHPINKISSTEPCTGDR 1067
Score = 74.9 bits (176), Expect = 3e-12
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEPCEGV 511
W + W PC K CG G Q + C ++ + + D KP+ R+ C PC
Sbjct: 851 WALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRR-CNQHPCSQP 909
Query: 512 DWMVSEWTGCD-TC-LATVRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
W+ EW C +C V++R QC+ ++V+ + C+ P PC ++
Sbjct: 910 VWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACA-GDRPEARRPC--LRV 966
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFC 595
P C QW WS+CS CG G + R+V C
Sbjct: 967 P-CPAQWRLGAWSQCSATCGEGIQQRQVVC 995
Score = 38.7 bits (86), Expect = 0.22
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQ 388
SW F SCS +CGGG++SR +C + C L P Q CN++ CP
Sbjct: 557 SWT--KFGSCSRSCGGGVRSRSRSCNNPS--PAYGGRPC---LGPMFEYQVCNSEECPGT 609
Query: 389 WVPGNWSRCSKR 400
+ +C+KR
Sbjct: 610 YEDFRAQQCAKR 621
>AL358817-5|CAI13857.1| 1226|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1226
Score = 244 bits (598), Expect = 2e-63
Identities = 169/537 (31%), Positives = 243/537 (45%), Gaps = 49/537 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV S+ R C P G C G +Y C +++CP DFRA+QCA+ N+
Sbjct: 567 CSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNS 626
Query: 117 V-TFRGKKYRWVPYLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVDG 172
+ K+ WVPY ++ CEL C + V DGTRC+ D + VC G
Sbjct: 627 YYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARG 686
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIY 232
C PVGCD +GS +DKC C G+ +C T K + + G ++ IP GA I
Sbjct: 687 ECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQ 746
Query: 233 ITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSL 291
I +E S + + ++++ G++ LN R+ T G W A + L++
Sbjct: 747 IEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVED----AKESLKTS 802
Query: 292 GPINEPLYLSLLLIDE---NVGVEYEYSLPIEKAPL---------PTQRYSWVHGNFSSC 339
GP+ E + + L E + Y+Y + + PL Y W +++ C
Sbjct: 803 GPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPC 862
Query: 340 SATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQAC-PPQWVPGNWSRC 397
S CGGGIQ CR R + +V LCD +P + CN C P WV W C
Sbjct: 863 SKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGAC 922
Query: 398 SKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFIS 456
S+ CGK G ++R ++C ++NG V+ K C G +P C + CP W +
Sbjct: 923 SRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKAC---AGDRPEARRPC-LRVPCPAQWRLG 978
Query: 457 PWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVS 516
W C CG G Q RQVVC R N S C ++P Q C L C G
Sbjct: 979 AWSQCSATCGEGIQQRQVVC------RTNANSLGHCEGDRPDTVQVCSLPACGG------ 1026
Query: 517 EWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE--EPCDKDKLPACQVQ 571
+ +TVR+ V + T + + V S HP + EPC D+ CQ++
Sbjct: 1027 -----NHQNSTVRADVWELGTPEGQWVPQSE-PLHPINKISSTEPCTGDRSVFCQME 1077
Score = 81.8 bits (193), Expect = 2e-14
Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 20/240 (8%)
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCD 561
LE + +W + W C C ++ C + D+ +V C + P + C+
Sbjct: 846 LEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCN 905
Query: 562 KDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDS 620
+ P Q W +W CS CG +G +TR + C KV + ++
Sbjct: 906 QH--PCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEAR 963
Query: 621 KPC-EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSC 679
+PC VP CP++W WS+C+ +CG+G++ R VVC C + PD+ C
Sbjct: 964 RPCLRVP---CPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHC-EGDRPDTVQVC 1019
Query: 680 NEQSCEALGEGSGYFTSLDLESTFPEIGSGTEIGKGFLKKSRYLTSINNTTSIKDCIVDQ 739
+ +C G + + + E+ GT G+ ++ +S L IN +S + C D+
Sbjct: 1020 SLPAC------GGNHQNSTVRADVWEL--GTPEGQ-WVPQSEPLHPINKISSTEPCTGDR 1070
Score = 74.9 bits (176), Expect = 3e-12
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEPCEGV 511
W + W PC K CG G Q + C ++ + + D KP+ R+ C PC
Sbjct: 854 WALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRR-CNQHPCSQP 912
Query: 512 DWMVSEWTGCD-TC-LATVRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
W+ EW C +C V++R QC+ ++V+ + C+ P PC ++
Sbjct: 913 VWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACA-GDRPEARRPC--LRV 969
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFC 595
P C QW WS+CS CG G + R+V C
Sbjct: 970 P-CPAQWRLGAWSQCSATCGEGIQQRQVVC 998
Score = 41.5 bits (93), Expect = 0.032
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQ 388
SW F SCS +CGGG++SR +C + LC L P Q CN++ CP
Sbjct: 560 SWT--KFGSCSRSCGGGVRSRSRSCNNPS--PAYGGRLC---LGPMFEYQVCNSEECPGT 612
Query: 389 WVPGNWSRCSKR 400
+ +C+KR
Sbjct: 613 YEDFRAQQCAKR 624
>AL358817-4|CAI13858.1| 1223|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1223
Score = 244 bits (598), Expect = 2e-63
Identities = 169/537 (31%), Positives = 243/537 (45%), Gaps = 49/537 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV S+ R C P G C G +Y C +++CP DFRA+QCA+ N+
Sbjct: 564 CSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNS 623
Query: 117 V-TFRGKKYRWVPYLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVDG 172
+ K+ WVPY ++ CEL C + V DGTRC+ D + VC G
Sbjct: 624 YYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARG 683
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIY 232
C PVGCD +GS +DKC C G+ +C T K + + G ++ IP GA I
Sbjct: 684 ECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQ 743
Query: 233 ITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSL 291
I +E S + + ++++ G++ LN R+ T G W A + L++
Sbjct: 744 IEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVED----AKESLKTS 799
Query: 292 GPINEPLYLSLLLIDE---NVGVEYEYSLPIEKAPL---------PTQRYSWVHGNFSSC 339
GP+ E + + L E + Y+Y + + PL Y W +++ C
Sbjct: 800 GPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPC 859
Query: 340 SATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQAC-PPQWVPGNWSRC 397
S CGGGIQ CR R + +V LCD +P + CN C P WV W C
Sbjct: 860 SKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGAC 919
Query: 398 SKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFIS 456
S+ CGK G ++R ++C ++NG V+ K C G +P C + CP W +
Sbjct: 920 SRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKAC---AGDRPEARRPC-LRVPCPAQWRLG 975
Query: 457 PWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVS 516
W C CG G Q RQVVC R N S C ++P Q C L C G
Sbjct: 976 AWSQCSATCGEGIQQRQVVC------RTNANSLGHCEGDRPDTVQVCSLPACGG------ 1023
Query: 517 EWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE--EPCDKDKLPACQVQ 571
+ +TVR+ V + T + + V S HP + EPC D+ CQ++
Sbjct: 1024 -----NHQNSTVRADVWELGTPEGQWVPQSE-PLHPINKISSTEPCTGDRSVFCQME 1074
Score = 81.8 bits (193), Expect = 2e-14
Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 20/240 (8%)
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCD 561
LE + +W + W C C ++ C + D+ +V C + P + C+
Sbjct: 843 LEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCN 902
Query: 562 KDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDS 620
+ P Q W +W CS CG +G +TR + C KV + ++
Sbjct: 903 QH--PCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEAR 960
Query: 621 KPC-EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSC 679
+PC VP CP++W WS+C+ +CG+G++ R VVC C + PD+ C
Sbjct: 961 RPCLRVP---CPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHC-EGDRPDTVQVC 1016
Query: 680 NEQSCEALGEGSGYFTSLDLESTFPEIGSGTEIGKGFLKKSRYLTSINNTTSIKDCIVDQ 739
+ +C G + + + E+ GT G+ ++ +S L IN +S + C D+
Sbjct: 1017 SLPAC------GGNHQNSTVRADVWEL--GTPEGQ-WVPQSEPLHPINKISSTEPCTGDR 1067
Score = 74.9 bits (176), Expect = 3e-12
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEPCEGV 511
W + W PC K CG G Q + C ++ + + D KP+ R+ C PC
Sbjct: 851 WALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRR-CNQHPCSQP 909
Query: 512 DWMVSEWTGCD-TC-LATVRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
W+ EW C +C V++R QC+ ++V+ + C+ P PC ++
Sbjct: 910 VWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACA-GDRPEARRPC--LRV 966
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFC 595
P C QW WS+CS CG G + R+V C
Sbjct: 967 P-CPAQWRLGAWSQCSATCGEGIQQRQVVC 995
Score = 41.5 bits (93), Expect = 0.032
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQ 388
SW F SCS +CGGG++SR +C + LC L P Q CN++ CP
Sbjct: 557 SWT--KFGSCSRSCGGGVRSRSRSCNNPS--PAYGGRLC---LGPMFEYQVCNSEECPGT 609
Query: 389 WVPGNWSRCSKR 400
+ +C+KR
Sbjct: 610 YEDFRAQQCAKR 621
>AL355344-5|CAI41278.1| 1226|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1226
Score = 244 bits (598), Expect = 2e-63
Identities = 169/537 (31%), Positives = 243/537 (45%), Gaps = 49/537 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV S+ R C P G C G +Y C +++CP DFRA+QCA+ N+
Sbjct: 567 CSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNS 626
Query: 117 V-TFRGKKYRWVPYLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVDG 172
+ K+ WVPY ++ CEL C + V DGTRC+ D + VC G
Sbjct: 627 YYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARG 686
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIY 232
C PVGCD +GS +DKC C G+ +C T K + + G ++ IP GA I
Sbjct: 687 ECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQ 746
Query: 233 ITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSL 291
I +E S + + ++++ G++ LN R+ T G W A + L++
Sbjct: 747 IEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVED----AKESLKTS 802
Query: 292 GPINEPLYLSLLLIDE---NVGVEYEYSLPIEKAPL---------PTQRYSWVHGNFSSC 339
GP+ E + + L E + Y+Y + + PL Y W +++ C
Sbjct: 803 GPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPC 862
Query: 340 SATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQAC-PPQWVPGNWSRC 397
S CGGGIQ CR R + +V LCD +P + CN C P WV W C
Sbjct: 863 SKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGAC 922
Query: 398 SKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFIS 456
S+ CGK G ++R ++C ++NG V+ K C G +P C + CP W +
Sbjct: 923 SRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKAC---AGDRPEARRPC-LRVPCPAQWRLG 978
Query: 457 PWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVS 516
W C CG G Q RQVVC R N S C ++P Q C L C G
Sbjct: 979 AWSQCSATCGEGIQQRQVVC------RTNANSLGHCEGDRPDTVQVCSLPACGG------ 1026
Query: 517 EWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE--EPCDKDKLPACQVQ 571
+ +TVR+ V + T + + V S HP + EPC D+ CQ++
Sbjct: 1027 -----NHQNSTVRADVWELGTPEGQWVPQSE-PLHPINKISSTEPCTGDRSVFCQME 1077
Score = 81.8 bits (193), Expect = 2e-14
Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 20/240 (8%)
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCD 561
LE + +W + W C C ++ C + D+ +V C + P + C+
Sbjct: 846 LEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCN 905
Query: 562 KDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDS 620
+ P Q W +W CS CG +G +TR + C KV + ++
Sbjct: 906 QH--PCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEAR 963
Query: 621 KPC-EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSC 679
+PC VP CP++W WS+C+ +CG+G++ R VVC C + PD+ C
Sbjct: 964 RPCLRVP---CPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHC-EGDRPDTVQVC 1019
Query: 680 NEQSCEALGEGSGYFTSLDLESTFPEIGSGTEIGKGFLKKSRYLTSINNTTSIKDCIVDQ 739
+ +C G + + + E+ GT G+ ++ +S L IN +S + C D+
Sbjct: 1020 SLPAC------GGNHQNSTVRADVWEL--GTPEGQ-WVPQSEPLHPINKISSTEPCTGDR 1070
Score = 74.9 bits (176), Expect = 3e-12
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEPCEGV 511
W + W PC K CG G Q + C ++ + + D KP+ R+ C PC
Sbjct: 854 WALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRR-CNQHPCSQP 912
Query: 512 DWMVSEWTGCD-TC-LATVRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
W+ EW C +C V++R QC+ ++V+ + C+ P PC ++
Sbjct: 913 VWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACA-GDRPEARRPC--LRV 969
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFC 595
P C QW WS+CS CG G + R+V C
Sbjct: 970 P-CPAQWRLGAWSQCSATCGEGIQQRQVVC 998
Score = 41.5 bits (93), Expect = 0.032
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQ 388
SW F SCS +CGGG++SR +C + LC L P Q CN++ CP
Sbjct: 560 SWT--KFGSCSRSCGGGVRSRSRSCNNPS--PAYGGRLC---LGPMFEYQVCNSEECPGT 612
Query: 389 WVPGNWSRCSKR 400
+ +C+KR
Sbjct: 613 YEDFRAQQCAKR 624
>AL355344-4|CAI41277.1| 1223|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 14 protein.
Length = 1223
Score = 244 bits (598), Expect = 2e-63
Identities = 169/537 (31%), Positives = 243/537 (45%), Gaps = 49/537 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV S+ R C P G C G +Y C +++CP DFRA+QCA+ N+
Sbjct: 564 CSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNS 623
Query: 117 V-TFRGKKYRWVPYLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVDG 172
+ K+ WVPY ++ CEL C + V DGTRC+ D + VC G
Sbjct: 624 YYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARG 683
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIY 232
C PVGCD +GS +DKC C G+ +C T K + + G ++ IP GA I
Sbjct: 684 ECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQ 743
Query: 233 ITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSL 291
I +E S + + ++++ G++ LN R+ T G W A + L++
Sbjct: 744 IEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVED----AKESLKTS 799
Query: 292 GPINEPLYLSLLLIDE---NVGVEYEYSLPIEKAPL---------PTQRYSWVHGNFSSC 339
GP+ E + + L E + Y+Y + + PL Y W +++ C
Sbjct: 800 GPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAPC 859
Query: 340 SATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQAC-PPQWVPGNWSRC 397
S CGGGIQ CR R + +V LCD +P + CN C P WV W C
Sbjct: 860 SKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCNQHPCSQPVWVTEEWGAC 919
Query: 398 SKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFIS 456
S+ CGK G ++R ++C ++NG V+ K C G +P C + CP W +
Sbjct: 920 SRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKAC---AGDRPEARRPC-LRVPCPAQWRLG 975
Query: 457 PWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVS 516
W C CG G Q RQVVC R N S C ++P Q C L C G
Sbjct: 976 AWSQCSATCGEGIQQRQVVC------RTNANSLGHCEGDRPDTVQVCSLPACGG------ 1023
Query: 517 EWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE--EPCDKDKLPACQVQ 571
+ +TVR+ V + T + + V S HP + EPC D+ CQ++
Sbjct: 1024 -----NHQNSTVRADVWELGTPEGQWVPQSE-PLHPINKISSTEPCTGDRSVFCQME 1074
Score = 81.8 bits (193), Expect = 2e-14
Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 20/240 (8%)
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCD 561
LE + +W + W C C ++ C + D+ +V C + P + C+
Sbjct: 843 LEEMDTYEWALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRRCN 902
Query: 562 KDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDS 620
+ P Q W +W CS CG +G +TR + C KV + ++
Sbjct: 903 QH--PCSQPVWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEAR 960
Query: 621 KPC-EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSC 679
+PC VP CP++W WS+C+ +CG+G++ R VVC C + PD+ C
Sbjct: 961 RPCLRVP---CPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHC-EGDRPDTVQVC 1016
Query: 680 NEQSCEALGEGSGYFTSLDLESTFPEIGSGTEIGKGFLKKSRYLTSINNTTSIKDCIVDQ 739
+ +C G + + + E+ GT G+ ++ +S L IN +S + C D+
Sbjct: 1017 SLPAC------GGNHQNSTVRADVWEL--GTPEGQ-WVPQSEPLHPINKISSTEPCTGDR 1067
Score = 74.9 bits (176), Expect = 3e-12
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 12/150 (8%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEPCEGV 511
W + W PC K CG G Q + C ++ + + D KP+ R+ C PC
Sbjct: 851 WALKSWAPCSKACGGGIQFTKYGCRRRRDHHMVQRHLCDHKKRPKPIRRR-CNQHPCSQP 909
Query: 512 DWMVSEWTGCD-TC-LATVRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
W+ EW C +C V++R QC+ ++V+ + C+ P PC ++
Sbjct: 910 VWVTEEWGACSRSCGKLGVQTRGIQCLLPLSNGTHKVMPAKACA-GDRPEARRPC--LRV 966
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFC 595
P C QW WS+CS CG G + R+V C
Sbjct: 967 P-CPAQWRLGAWSQCSATCGEGIQQRQVVC 995
Score = 41.5 bits (93), Expect = 0.032
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQ 388
SW F SCS +CGGG++SR +C + LC L P Q CN++ CP
Sbjct: 557 SWT--KFGSCSRSCGGGVRSRSRSCNNPS--PAYGGRLC---LGPMFEYQVCNSEECPGT 609
Query: 389 WVPGNWSRCSKR 400
+ +C+KR
Sbjct: 610 YEDFRAQQCAKR 621
>AJ345098-1|CAC87943.1| 1223|Homo sapiens metalloprotease-disintegrin
protease protein.
Length = 1223
Score = 235 bits (574), Expect = 2e-60
Identities = 167/538 (31%), Positives = 241/538 (44%), Gaps = 51/538 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP--NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN 115
CSR+CGGGV S+ R C P G P C G +Y C +++CP DFRA+QCA+ N
Sbjct: 564 CSRSCGGGVRSRSRSCNNPSPAYGGRP-CLGPMFEYQVCNSEECPGTYEDFRAQQCAKRN 622
Query: 116 NV-TFRGKKYRWVPYLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVD 171
+ + K+ WVPY ++ CEL C + V DGTRC+ D + VC
Sbjct: 623 SYYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCAR 682
Query: 172 GVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTI 231
G C PVGCD +GS +DKC C G+ +C T K + + G ++ IP GA I
Sbjct: 683 GECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHI 742
Query: 232 YITEIEPSNNYLALRSK-NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRS 290
I +E S + + ++++ G++ LN R+ T G W A + L++
Sbjct: 743 QIEALEKSPHRIVVKNQVTGSFILNPKGKEATSRTFTAMGLEWEDAVED----AKESLKT 798
Query: 291 LGPINEPLYLSLLLIDE---NVGVEYEYSLPIEKAPL---------PTQRYSWVHGNFSS 338
GP+ E + + L E + Y+Y + + PL Y W +++
Sbjct: 799 SGPLPEAIAILALPPTEGGPRSSLAYKYVIHEDLLPLIGSNNVLLEEMDTYEWALKSWAP 858
Query: 339 CSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNTQAC-PPQWVPGNWSR 396
CS CGGGI+ CR R + +V LCD +P + N C P WV W
Sbjct: 859 CSKACGGGIRFTKYGCRRRRDHHMVHRHLCDHKKRPKPIRRRSNQHPCSQPVWVTEEWGA 918
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT-WFI 455
CS+ GK G ++R ++C ++NG V+ K C G +P C + CP W +
Sbjct: 919 CSRSYGKLGVQTRGIQCLLPLSNGTHKVMPAKAC---AGDRPEARRPC-LRVPCPAQWRL 974
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
W C CG G Q RQVVC R N S C ++P Q C L C G
Sbjct: 975 GAWSQCSATCGEGIQQRQVVC------RTNANSLGHCEGDRPDTVQVCSLPACGGSHQN- 1027
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE--EPCDKDKLPACQVQ 571
+TVR+ V + T + + V S HP + EPC D+ CQ++
Sbjct: 1028 ----------STVRADVWELGTPEGQWVPQSE-PLHPINKISSTEPCTGDRSVFCQME 1074
Score = 76.6 bits (180), Expect = 9e-13
Identities = 60/241 (24%), Positives = 104/241 (43%), Gaps = 22/241 (9%)
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPALEEPCDK 562
LE + +W + W C C +R C + D+ +V+ C + P +P +
Sbjct: 843 LEEMDTYEWALKSWAPCSKACGGGIRFTKYGCRRRRDHHMVHRHLCDHKKRP---KPIRR 899
Query: 563 --DKLPACQVQWYATQWSKCSVECG-VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
++ P Q W +W CS G +G +TR + C KV + ++
Sbjct: 900 RSNQHPCSQPVWVTEEWGACSRSYGKLGVQTRGIQCLLPLSNGTHKVMPAKACAGDRPEA 959
Query: 620 SKPC-EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGS 678
+PC VP CP++W WS+C+ +CG+G++ R VVC C + PD+
Sbjct: 960 RRPCLRVP---CPAQWRLGAWSQCSATCGEGIQQRQVVCRTNANSLGHC-EGDRPDTVQV 1015
Query: 679 CNEQSCEALGEGSGYFTSLDLESTFPEIGSGTEIGKGFLKKSRYLTSINNTTSIKDCIVD 738
C+ +C G + + + E+ GT G+ ++ +S L IN +S + C D
Sbjct: 1016 CSLPAC------GGSHQNSTVRADVWEL--GTPEGQ-WVPQSEPLHPINKISSTEPCTGD 1066
Query: 739 Q 739
+
Sbjct: 1067 R 1067
Score = 70.1 bits (164), Expect = 8e-11
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEPCEGV 511
W + W PC K CG G + + C ++ + ++ D KP+ R+ + PC
Sbjct: 851 WALKSWAPCSKACGGGIRFTKYGCRRRRDHHMVHRHLCDHKKRPKPIRRRSNQ-HPCSQP 909
Query: 512 DWMVSEWTGCDTCLAT--VRSRVAQCV----TKDYRVVNSSFCSYHPTPALEEPCDKDKL 565
W+ EW C V++R QC+ ++V+ + C+ P PC ++
Sbjct: 910 VWVTEEWGACSRSYGKLGVQTRGIQCLLPLSNGTHKVMPAKACA-GDRPEARRPC--LRV 966
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFC 595
P C QW WS+CS CG G + R+V C
Sbjct: 967 P-CPAQWRLGAWSQCSATCGEGIQQRQVVC 995
Score = 38.7 bits (86), Expect = 0.22
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 8/72 (11%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQ 388
SW F SCS +CGGG++SR +C + C L P Q CN++ CP
Sbjct: 557 SWT--KFGSCSRSCGGGVRSRSRSCNNPS--PAYGGRPC---LGPMFEYQVCNSEECPGT 609
Query: 389 WVPGNWSRCSKR 400
+ +C+KR
Sbjct: 610 YEDFRAQQCAKR 621
>AY358122-1|AAQ88489.1| 877|Homo sapiens ENWT2803 protein.
Length = 877
Score = 233 bits (570), Expect = 5e-60
Identities = 155/508 (30%), Positives = 221/508 (43%), Gaps = 29/508 (5%)
Query: 82 PQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNVTFRGKKYRWVPYLKV--SKPCELT 139
P+C+G + +C CP D RA QCA +N+ F G+ Y+W P+ +V S+ CEL
Sbjct: 362 PRCSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQLYQWEPFTEVQGSQRCELN 421
Query: 140 CMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNG 199
C G RFY RH EKV DGT C + D+CV G C GCD +LGS + D C C G+
Sbjct: 422 CRPRGFRFYVRHTEKVQDGTLCQPGAPDICVAGRCLSPGCDGILGSGRRPDGCGVCGGDD 481
Query: 200 HNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYH 259
C + + GY IL IP GA + I ++ PS+NYLALR G +NG++
Sbjct: 482 STCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWA 541
Query: 260 IDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL-- 317
+D P S G ++ Y R + + L + GP +P+ + ++ +EN GV Y+Y +
Sbjct: 542 VDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIFQEENPGVFYQYVISS 601
Query: 318 --PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA 375
PI + P P + + + ++ + PA
Sbjct: 602 PPPILENPTPEPPVPQLQPEILRVEPPLAPAPRPARTPGTLQRQVRIPQ--------MPA 653
Query: 376 TNQTCNTQACP-PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLL 434
P W S CS CGK G C I+ +D++ C
Sbjct: 654 PPHPRTPLGSPAAYWKRVGHSACSASCGK-GVWRPIFLC---ISRESGEELDERSCAAGA 709
Query: 435 GPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE 494
P PA E C+ P W W C + CG G Q RQ+ C Q+ G + + + C
Sbjct: 710 RP-PASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGH 768
Query: 495 -EKPLDRQPCELEPCEGVDWMV-SEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFC-SY 550
+P Q C+L C W V S W+ C C RSR +CV + V+ C S
Sbjct: 769 LPRPNITQSCQLRLCG--HWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASG 826
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWS 578
P P E CD + C W+ + WS
Sbjct: 827 PPQPPSREACD---MGPCTTAWFHSDWS 851
Score = 71.3 bits (167), Expect = 3e-11
Identities = 49/187 (26%), Positives = 83/187 (44%), Gaps = 18/187 (9%)
Query: 461 CDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE--EKPLDRQPCELEPCEGVDWMVSEW 518
C CG G +C + +G L + C+ P +PC PC W EW
Sbjct: 676 CSASCGKGVWRPIFLCISRESGE--ELDERSCAAGARPPASPEPCHGTPCPPY-WEAGEW 732
Query: 519 TGCD-TCLATVRSRVAQCVTKDYRVVNSSF----CSYHPTPALEEPCDKDKLPACQVQWY 573
T C +C + R QC +++ SS C + P P + + C +L C
Sbjct: 733 TSCSRSCGPGTQHRQLQC-RQEFGGGGSSVPPERCGHLPRPNITQSC---QLRLCGHWEV 788
Query: 574 ATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV CG G+++R+V C +G V + + ++ P + ++ C++ C +
Sbjct: 789 GSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREA--CDM--GPCTTA 844
Query: 634 WYAAPWS 640
W+ + WS
Sbjct: 845 WFHSDWS 851
Score = 66.5 bits (155), Expect = 1e-09
Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 9/135 (6%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA EPC C W A +W+ CS CG G + R++ C + G V C
Sbjct: 712 PASPEPCHGTP---CPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGH 768
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFS--DCPK- 669
+ N ++ C++ C +PWS+C+ CG+G R R V C+ G E S +C
Sbjct: 769 LPRPNITQSCQL--RLCGHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASG 826
Query: 670 KSLPDSAGSCNEQSC 684
P S +C+ C
Sbjct: 827 PPQPPSREACDMGPC 841
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 11/133 (8%)
Query: 559 PCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYN 618
P + L + W S CS CG G C S ++D+ +C +
Sbjct: 655 PHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLC--ISRESGEELDERSCAAGARPP 712
Query: 619 DS-KPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR--GGKEFSDCPKK----S 671
S +PC CP W A W+ C++SCG G + R + C + GG S P++
Sbjct: 713 ASPEPCH--GTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLP 770
Query: 672 LPDSAGSCNEQSC 684
P+ SC + C
Sbjct: 771 RPNITQSCQLRLC 783
>AL356356-12|CAI15499.1| 877|Homo sapiens ADAMTS-like 4 protein.
Length = 877
Score = 233 bits (570), Expect = 5e-60
Identities = 155/508 (30%), Positives = 221/508 (43%), Gaps = 29/508 (5%)
Query: 82 PQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNVTFRGKKYRWVPYLKV--SKPCELT 139
P+C+G + +C CP D RA QCA +N+ F G+ Y+W P+ +V S+ CEL
Sbjct: 362 PRCSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQLYQWEPFTEVQGSQRCELN 421
Query: 140 CMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNG 199
C G RFY RH EKV DGT C + D+CV G C GCD +LGS + D C C G+
Sbjct: 422 CRPRGFRFYVRHTEKVQDGTLCQPGAPDICVAGRCLSPGCDGILGSGRRPDGCGVCGGDD 481
Query: 200 HNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYH 259
C + + GY IL IP GA + I ++ PS+NYLALR G +NG++
Sbjct: 482 STCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWA 541
Query: 260 IDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL-- 317
+D P S G ++ Y R + + L + GP +P+ + ++ +EN GV Y+Y +
Sbjct: 542 VDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIFQEENPGVFYQYVISS 601
Query: 318 --PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA 375
PI + P P + + + ++ + PA
Sbjct: 602 PPPILENPTPEPPVPQLQPEILRVEPPLAPAPRPARTPGTLQRQVRIPQ--------MPA 653
Query: 376 TNQTCNTQACP-PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLL 434
P W S CS CGK G C I+ +D++ C
Sbjct: 654 PPHPRTPLGSPAAYWKRVGHSACSASCGK-GVWRPIFLC---ISRESGEELDERSCAAGA 709
Query: 435 GPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE 494
P PA E C+ P W W C + CG G Q RQ+ C Q+ G + + + C
Sbjct: 710 RP-PASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGH 768
Query: 495 -EKPLDRQPCELEPCEGVDWMV-SEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFC-SY 550
+P Q C+L C W V S W+ C C RSR +CV + V+ C S
Sbjct: 769 LPRPNITQSCQLRLCG--HWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASG 826
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWS 578
P P E CD + C W+ + WS
Sbjct: 827 PPQPPSREACD---MGPCTTAWFHSDWS 851
Score = 71.3 bits (167), Expect = 3e-11
Identities = 49/187 (26%), Positives = 83/187 (44%), Gaps = 18/187 (9%)
Query: 461 CDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE--EKPLDRQPCELEPCEGVDWMVSEW 518
C CG G +C + +G L + C+ P +PC PC W EW
Sbjct: 676 CSASCGKGVWRPIFLCISRESGE--ELDERSCAAGARPPASPEPCHGTPCPPY-WEAGEW 732
Query: 519 TGCD-TCLATVRSRVAQCVTKDYRVVNSSF----CSYHPTPALEEPCDKDKLPACQVQWY 573
T C +C + R QC +++ SS C + P P + + C +L C
Sbjct: 733 TSCSRSCGPGTQHRQLQC-RQEFGGGGSSVPPERCGHLPRPNITQSC---QLRLCGHWEV 788
Query: 574 ATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV CG G+++R+V C +G V + + ++ P + ++ C++ C +
Sbjct: 789 GSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREA--CDM--GPCTTA 844
Query: 634 WYAAPWS 640
W+ + WS
Sbjct: 845 WFHSDWS 851
Score = 66.5 bits (155), Expect = 1e-09
Identities = 41/135 (30%), Positives = 60/135 (44%), Gaps = 9/135 (6%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA EPC C W A +W+ CS CG G + R++ C + G V C
Sbjct: 712 PASPEPCHGTP---CPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGH 768
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFS--DCPK- 669
+ N ++ C++ C +PWS+C+ CG+G R R V C+ G E S +C
Sbjct: 769 LPRPNITQSCQL--RLCGHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASG 826
Query: 670 KSLPDSAGSCNEQSC 684
P S +C+ C
Sbjct: 827 PPQPPSREACDMGPC 841
Score = 48.0 bits (109), Expect = 4e-04
Identities = 36/133 (27%), Positives = 54/133 (40%), Gaps = 11/133 (8%)
Query: 559 PCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYN 618
P + L + W S CS CG G C S ++D+ +C +
Sbjct: 655 PHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLC--ISRESGEELDERSCAAGARPP 712
Query: 619 DS-KPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR--GGKEFSDCPKK----S 671
S +PC CP W A W+ C++SCG G + R + C + GG S P++
Sbjct: 713 ASPEPCH--GTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLP 770
Query: 672 LPDSAGSCNEQSC 684
P+ SC + C
Sbjct: 771 RPNITQSCQLRLC 783
>AF176313-1|AAK84170.1| 525|Homo sapiens ADAM-TS related protein 1
protein.
Length = 525
Score = 222 bits (543), Expect = 9e-57
Identities = 139/445 (31%), Positives = 201/445 (45%), Gaps = 52/445 (11%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNV 117
CSRTCGGG A+ R CL C G + +Y +C DCP + DFRA+QC+ +N+V
Sbjct: 45 CSRTCGGGAANSLRRCLS-----SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDV 99
Query: 118 TFRGKKYRWVPYLK-VSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQP 176
G+ Y W+P PC L C G KV+DGTRC +S D+C+ G+CQ
Sbjct: 100 KHHGQFYEWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQI 159
Query: 177 VGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQ-DLRKGYNDILLIPEGATTIYITE 235
VGCD LGS KED C C G+G C + +Q K + ++ IP G+ I +
Sbjct: 160 VGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVL 219
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDK--LRSLGP 293
P + YL ++ GT G+ + + + + ++++ PDK LR GP
Sbjct: 220 KGPDHLYLETKTLQGT---KGENSLSSTGTFLVDNSSVDFQK------FPDKEILRMAGP 270
Query: 294 INEPLYLSLLLI-DENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDV 352
+ + + + V++ + PI + W +F CSATCGGG Q
Sbjct: 271 LTADFIVKIRNSGSADSTVQFIFYQPI--------IHRWRETDFFPCSATCGGGYQLTSA 322
Query: 353 TCRSREELEVVDEGLC---DDGLKPATN-QTCNTQACP-----------------PQWVP 391
C VV + C + +KP Q CN CP P+W
Sbjct: 323 ECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPASDGYKQIMPYDLYHPLPRWEA 382
Query: 392 GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP 451
W+ CS CG G +SR V C + G + V++ +C + PK + + CN+ CP
Sbjct: 383 TPWTACSSSCG-GGIQSRAVSCVEEDIQGHVTSVEEWKC--MYTPKMPIAQPCNI-FDCP 438
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVC 476
W W PC CG G + R V+C
Sbjct: 439 KWLAQEWSPCTVTCGQGLRYRVVLC 463
Score = 87.0 bits (206), Expect = 6e-16
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 27/190 (14%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVT-KDYRVVNSSFCSYHPT-----PALEEPCDKDKL 565
W +++ C TC + A+C + RVV +C Y+P P L+E C+ D
Sbjct: 301 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQE-CNLDPC 359
Query: 566 PAC----QV----------QWYATQWSKCSVECGVGKKTRRVFCGKFD-GASVMKVDDSN 610
PA Q+ +W AT W+ CS CG G ++R V C + D V V++
Sbjct: 360 PASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWK 419
Query: 611 CPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPK 669
C K ++PC + + CP KW A WS CT +CG+GLR+R V+C+ G C
Sbjct: 420 CMYTPKMPIAQPCNIFD--CP-KWLAQEWSPCTVTCGQGLRYRVVLCIDHRGMHTGGCSP 476
Query: 670 KSLPDSAGSC 679
K+ P C
Sbjct: 477 KTKPHIKEEC 486
Score = 74.1 bits (174), Expect = 5e-12
Identities = 65/238 (27%), Positives = 104/238 (43%), Gaps = 43/238 (18%)
Query: 369 DDGLKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
+ G +T Q Q +W ++ CS CG G + C + +N VV D+
Sbjct: 281 NSGSADSTVQFIFYQPIIHRWRETDFFPCSATCG-GGYQLTSAECYDLRSN---RVVADQ 336
Query: 429 ECF---DLLGPKPALYESCNVDAA-----------------CPTWFISPWKPCDKLCGSG 468
C + + PKP L E CN+D P W +PW C CG G
Sbjct: 337 YCHYYPENIKPKPKLQE-CNLDPCPASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGG 395
Query: 469 QQTRQVVCYQKN-NGRINVLSDDEC--SEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TC 524
Q+R V C +++ G + + + +C + + P+ QPC + C W+ EW+ C TC
Sbjct: 396 IQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPI-AQPCNIFDCP--KWLAQEWSPCTVTC 452
Query: 525 LATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC--------DKDKLPA-CQVQWY 573
+R RV C+ D+R +++ CS P ++E C K+KLP ++ W+
Sbjct: 453 GQGLRYRVVLCI--DHRGMHTGGCSPKTKPHIKEECIVPTPCYKPKEKLPVEAKLPWF 508
Score = 35.1 bits (77), Expect = 2.7
Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 7/67 (10%)
Query: 627 EEKCPSKWYA-APWSECTKSCGKG----LR--FRSVVCLRGGKEFSDCPKKSLPDSAGSC 679
EE W A PWSEC+++CG G LR S C + C P AG
Sbjct: 29 EEDRDGLWDAWGPWSECSRTCGGGAANSLRRCLSSKSCEGRNIRYRTCSNVDCPPEAGDF 88
Query: 680 NEQSCEA 686
Q C A
Sbjct: 89 RAQQCSA 95
>BC036515-1|AAH36515.1| 967|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 1 protein.
Length = 967
Score = 221 bits (539), Expect = 3e-56
Identities = 140/401 (34%), Positives = 204/401 (50%), Gaps = 37/401 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G +Y SC +DCP+N+ FR EQC +N
Sbjct: 571 CSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHN 630
Query: 116 N---VTF-RGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+F G W+P Y VS C+L C G +++ + KV+DGT C+ DS V
Sbjct: 631 EFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSTDSTSV 690
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLI-NTQDLRKGYNDILLIPEG 227
CV G C GCD ++ S K DKC C GNG C KK+ + + GY+DI+ IP G
Sbjct: 691 CVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTC---KKISGSVTSAKPGYHDIITIPTG 747
Query: 228 ATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQG 281
AT I + + + ++LA+++ +GTY LNGDY + + + G + Y +
Sbjct: 748 ATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDYTLSTLEQDIMYKGVVLRYSGSS-- 805
Query: 282 ITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKA-----PLPTQRYSWVHGNF 336
A +++RS P+ EPL + +L + + + +Y+ ++K +PT +WV +
Sbjct: 806 -AALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFS-AWVIEEW 863
Query: 337 SSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSR 396
CS +C G Q R V CR ++ C +KPA+ + C C PQW G WS
Sbjct: 864 GECSKSCELGWQRRLVECR---DINGQPASECAKEVKPASTRPCADHPC-PQWQLGEWSS 919
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CSK CGK G + R ++C + +G V+ + C L PK
Sbjct: 920 CSKTCGK-GYKKRSLKC--LSHDG--GVLSHESCDPLKKPK 955
Score = 66.9 bits (156), Expect = 7e-10
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W +W +CS C +G + R V C +G S C KE K ++PC + CP
Sbjct: 858 WVIEEWGECSKSCELGWQRRLVECRDINGQPA-----SECAKEVKPASTRPCA--DHPCP 910
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL 658
+W WS C+K+CGKG + RS+ CL
Sbjct: 911 -QWQLGEWSSCSKTCGKGYKKRSLKCL 936
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/108 (36%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
WV W CSK C + G + R V C I NG P+ KE KPA C D
Sbjct: 858 WVIEEWGECSKSC-ELGWQRRLVECRDI--NGQPASECAKEV------KPASTRPC-ADH 907
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
CP W + W C K CG G + R + C + G VLS + C K
Sbjct: 908 PCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGG---VLSHESCDPLK 952
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
ES N W I W C K C G Q R V C IN EC++E KP
Sbjct: 847 ESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRD-----INGQPASECAKEVKPAST 901
Query: 501 QPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
+PC PC W + EW+ C TC + R +C++ D V++ C
Sbjct: 902 RPCADHPCP--QWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESC 948
Score = 53.6 bits (123), Expect = 7e-06
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W++ EW C +C + R+ +C +D +S C+ PA PC P Q
Sbjct: 858 WVIEEWGECSKSCELGWQRRLVEC--RDINGQPASECAKEVKPASTRPCADHPCP----Q 911
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDG 600
W +WS CS CG G K R + C DG
Sbjct: 912 WQLGEWSSCSKTCGKGYKKRSLKCLSHDG 940
Score = 42.7 bits (96), Expect = 0.014
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCE--ALG 688
S W W EC+KSC G + R V C G+ S+C K+ P S C + C LG
Sbjct: 856 SAWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPASTRPCADHPCPQWQLG 915
Query: 689 EGS 691
E S
Sbjct: 916 EWS 918
Score = 34.3 bits (75), Expect = 4.8
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 619 DSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSD 666
D K + P W PW +C+++CG G+++ C GGK +
Sbjct: 550 DRKHFDTPFHGSWGMW--GPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRS 607
Query: 667 CPKKSLPDSAG-SCNEQSCEALGEGS 691
C + PD+ G + E+ CEA E S
Sbjct: 608 CNLEDCPDNNGKTFREEQCEAHNEFS 633
>AP001697-1|BAA95502.1| 967|Homo sapiens metalloprotease with
thrombospondin type 1 motifs protein.
Length = 967
Score = 221 bits (539), Expect = 3e-56
Identities = 140/401 (34%), Positives = 204/401 (50%), Gaps = 37/401 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G +Y SC +DCP+N+ FR EQC +N
Sbjct: 571 CSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHN 630
Query: 116 N---VTF-RGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+F G W+P Y VS C+L C G +++ + KV+DGT C+ DS V
Sbjct: 631 EFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDSTSV 690
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLI-NTQDLRKGYNDILLIPEG 227
CV G C GCD ++ S K DKC C GNG C KK+ + + GY+DI+ IP G
Sbjct: 691 CVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTC---KKISGSVTSAKPGYHDIITIPTG 747
Query: 228 ATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQG 281
AT I + + + ++LA+++ +GTY LNGDY + + + G + Y +
Sbjct: 748 ATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDYTLSTLEQDIMYKGVVLRYSGSS-- 805
Query: 282 ITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKA-----PLPTQRYSWVHGNF 336
A +++RS P+ EPL + +L + + + +Y+ ++K +PT +WV +
Sbjct: 806 -AALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFS-AWVIEEW 863
Query: 337 SSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSR 396
CS +C G Q R V CR ++ C +KPA+ + C C PQW G WS
Sbjct: 864 GECSKSCELGWQRRLVECR---DINGQPASECAKEVKPASTRPCADHPC-PQWQLGEWSS 919
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CSK CGK G + R ++C + +G V+ + C L PK
Sbjct: 920 CSKTCGK-GYKKRSLKC--LSHDG--GVLSHESCDPLKKPK 955
Score = 66.9 bits (156), Expect = 7e-10
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W +W +CS C +G + R V C +G S C KE K ++PC + CP
Sbjct: 858 WVIEEWGECSKSCELGWQRRLVECRDINGQPA-----SECAKEVKPASTRPCA--DHPCP 910
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL 658
+W WS C+K+CGKG + RS+ CL
Sbjct: 911 -QWQLGEWSSCSKTCGKGYKKRSLKCL 936
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/108 (36%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
WV W CSK C + G + R V C I NG P+ KE KPA C D
Sbjct: 858 WVIEEWGECSKSC-ELGWQRRLVECRDI--NGQPASECAKEV------KPASTRPC-ADH 907
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
CP W + W C K CG G + R + C + G VLS + C K
Sbjct: 908 PCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGG---VLSHESCDPLK 952
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
ES N W I W C K C G Q R V C IN EC++E KP
Sbjct: 847 ESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRD-----INGQPASECAKEVKPAST 901
Query: 501 QPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
+PC PC W + EW+ C TC + R +C++ D V++ C
Sbjct: 902 RPCADHPCP--QWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESC 948
Score = 53.6 bits (123), Expect = 7e-06
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W++ EW C +C + R+ +C +D +S C+ PA PC P Q
Sbjct: 858 WVIEEWGECSKSCELGWQRRLVEC--RDINGQPASECAKEVKPASTRPCADHPCP----Q 911
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDG 600
W +WS CS CG G K R + C DG
Sbjct: 912 WQLGEWSSCSKTCGKGYKKRSLKCLSHDG 940
Score = 42.7 bits (96), Expect = 0.014
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCE--ALG 688
S W W EC+KSC G + R V C G+ S+C K+ P S C + C LG
Sbjct: 856 SAWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPASTRPCADHPCPQWQLG 915
Query: 689 EGS 691
E S
Sbjct: 916 EWS 918
Score = 34.3 bits (75), Expect = 4.8
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 619 DSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSD 666
D K + P W PW +C+++CG G+++ C GGK +
Sbjct: 550 DRKHFDTPFHGSWGMW--GPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRS 607
Query: 667 CPKKSLPDSAG-SCNEQSCEALGEGS 691
C + PD+ G + E+ CEA E S
Sbjct: 608 CNLEDCPDNNGKTFREEQCEAHNEFS 633
>AL162080-1|CAB82413.1| 550|Homo sapiens hypothetical protein
protein.
Length = 550
Score = 221 bits (539), Expect = 3e-56
Identities = 140/401 (34%), Positives = 204/401 (50%), Gaps = 37/401 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G +Y SC +DCP+N+ FR EQC +N
Sbjct: 154 CSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHN 213
Query: 116 N---VTF-RGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+F G W+P Y VS C+L C G +++ + KV+DGT C+ DS V
Sbjct: 214 EFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDSTSV 273
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLI-NTQDLRKGYNDILLIPEG 227
CV G C GCD ++ S K DKC C GNG C KK+ + + GY+DI+ IP G
Sbjct: 274 CVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTC---KKISGSVTSAKPGYHDIITIPTG 330
Query: 228 ATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQG 281
AT I + + + ++LA+++ +GTY LNGDY + + + G + Y +
Sbjct: 331 ATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDYTLSTLEQDIMYKGVVLRYSGSS-- 388
Query: 282 ITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKA-----PLPTQRYSWVHGNF 336
A +++RS P+ EPL + +L + + + +Y+ ++K +PT +WV +
Sbjct: 389 -AALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFS-AWVIEEW 446
Query: 337 SSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSR 396
CS +C G Q R V CR ++ C +KPA+ + C C PQW G WS
Sbjct: 447 GECSKSCELGWQRRLVECR---DINGQPASECAKEVKPASTRPCADHPC-PQWQLGEWSS 502
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CSK CGK G + R ++C + +G V+ + C L PK
Sbjct: 503 CSKTCGK-GYKKRSLKC--LSHDG--GVLSHESCDPLKKPK 538
Score = 66.9 bits (156), Expect = 7e-10
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W +W +CS C +G + R V C +G S C KE K ++PC + CP
Sbjct: 441 WVIEEWGECSKSCELGWQRRLVECRDINGQPA-----SECAKEVKPASTRPCA--DHPCP 493
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL 658
+W WS C+K+CGKG + RS+ CL
Sbjct: 494 -QWQLGEWSSCSKTCGKGYKKRSLKCL 519
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/108 (36%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
WV W CSK C + G + R V C I NG P+ KE KPA C D
Sbjct: 441 WVIEEWGECSKSC-ELGWQRRLVECRDI--NGQPASECAKEV------KPASTRPC-ADH 490
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
CP W + W C K CG G + R + C + G VLS + C K
Sbjct: 491 PCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGG---VLSHESCDPLK 535
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
ES N W I W C K C G Q R V C IN EC++E KP
Sbjct: 430 ESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRD-----INGQPASECAKEVKPAST 484
Query: 501 QPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
+PC PC W + EW+ C TC + R +C++ D V++ C
Sbjct: 485 RPCADHPCP--QWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESC 531
Score = 53.6 bits (123), Expect = 7e-06
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W++ EW C +C + R+ +C +D +S C+ PA PC P Q
Sbjct: 441 WVIEEWGECSKSCELGWQRRLVEC--RDINGQPASECAKEVKPASTRPCADHPCP----Q 494
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDG 600
W +WS CS CG G K R + C DG
Sbjct: 495 WQLGEWSSCSKTCGKGYKKRSLKCLSHDG 523
Score = 42.7 bits (96), Expect = 0.014
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCE--ALG 688
S W W EC+KSC G + R V C G+ S+C K+ P S C + C LG
Sbjct: 439 SAWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPASTRPCADHPCPQWQLG 498
Query: 689 EGS 691
E S
Sbjct: 499 EWS 501
Score = 34.3 bits (75), Expect = 4.8
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 619 DSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSD 666
D K + P W PW +C+++CG G+++ C GGK +
Sbjct: 133 DRKHFDTPFHGSWGMW--GPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRS 190
Query: 667 CPKKSLPDSAG-SCNEQSCEALGEGS 691
C + PD+ G + E+ CEA E S
Sbjct: 191 CNLEDCPDNNGKTFREEQCEAHNEFS 216
>AF207664-1|AAF23772.1| 967|Homo sapiens matrix metalloprotease
protein.
Length = 967
Score = 221 bits (539), Expect = 3e-56
Identities = 140/401 (34%), Positives = 204/401 (50%), Gaps = 37/401 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G +Y SC +DCP+N+ FR EQC +N
Sbjct: 571 CSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHN 630
Query: 116 N---VTF-RGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+F G W+P Y VS C+L C G +++ + KV+DGT C+ DS V
Sbjct: 631 EFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDSTSV 690
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLI-NTQDLRKGYNDILLIPEG 227
CV G C GCD ++ S K DKC C GNG C KK+ + + GY+DI+ IP G
Sbjct: 691 CVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTC---KKISGSVTSAKPGYHDIITIPTG 747
Query: 228 ATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQG 281
AT I + + + ++LA+++ +GTY LNGDY + + + G + Y +
Sbjct: 748 ATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDYTLSTLEQDIMYKGVVLRYSGSS-- 805
Query: 282 ITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKA-----PLPTQRYSWVHGNF 336
A +++RS P+ EPL + +L + + + +Y+ ++K +PT +WV +
Sbjct: 806 -AALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFS-AWVIEEW 863
Query: 337 SSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSR 396
CS +C G Q R V CR ++ C +KPA+ + C C PQW G WS
Sbjct: 864 GECSKSCELGWQRRLVECR---DINGQPASECAKEVKPASTRPCADHPC-PQWQLGEWSS 919
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CSK CGK G + R ++C + +G V+ + C L PK
Sbjct: 920 CSKTCGK-GYKKRSLKC--LSHDG--GVLSHESCDPLKKPK 955
Score = 66.9 bits (156), Expect = 7e-10
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W +W +CS C +G + R V C +G S C KE K ++PC + CP
Sbjct: 858 WVIEEWGECSKSCELGWQRRLVECRDINGQPA-----SECAKEVKPASTRPCA--DHPCP 910
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL 658
+W WS C+K+CGKG + RS+ CL
Sbjct: 911 -QWQLGEWSSCSKTCGKGYKKRSLKCL 936
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/108 (36%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
WV W CSK C + G + R V C I NG P+ KE KPA C D
Sbjct: 858 WVIEEWGECSKSC-ELGWQRRLVECRDI--NGQPASECAKEV------KPASTRPC-ADH 907
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
CP W + W C K CG G + R + C + G VLS + C K
Sbjct: 908 PCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGG---VLSHESCDPLK 952
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
ES N W I W C K C G Q R V C IN EC++E KP
Sbjct: 847 ESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRD-----INGQPASECAKEVKPAST 901
Query: 501 QPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
+PC PC W + EW+ C TC + R +C++ D V++ C
Sbjct: 902 RPCADHPCP--QWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESC 948
Score = 53.6 bits (123), Expect = 7e-06
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W++ EW C +C + R+ +C +D +S C+ PA PC P Q
Sbjct: 858 WVIEEWGECSKSCELGWQRRLVEC--RDINGQPASECAKEVKPASTRPCADHPCP----Q 911
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDG 600
W +WS CS CG G K R + C DG
Sbjct: 912 WQLGEWSSCSKTCGKGYKKRSLKCLSHDG 940
Score = 42.7 bits (96), Expect = 0.014
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCE--ALG 688
S W W EC+KSC G + R V C G+ S+C K+ P S C + C LG
Sbjct: 856 SAWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPASTRPCADHPCPQWQLG 915
Query: 689 EGS 691
E S
Sbjct: 916 EWS 918
Score = 34.3 bits (75), Expect = 4.8
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 619 DSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSD 666
D K + P W PW +C+++CG G+++ C GGK +
Sbjct: 550 DRKHFDTPFHGSWGMW--GPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRS 607
Query: 667 CPKKSLPDSAG-SCNEQSCEALGEGS 691
C + PD+ G + E+ CEA E S
Sbjct: 608 CNLEDCPDNNGKTFREEQCEAHNEFS 633
>AF170084-1|AAF15317.1| 967|Homo sapiens metalloproteinase with
thrombospondin type 1 motifs ADAMTS1 protein.
Length = 967
Score = 221 bits (539), Expect = 3e-56
Identities = 140/401 (34%), Positives = 204/401 (50%), Gaps = 37/401 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G +Y SC +DCP+N+ FR EQC +N
Sbjct: 571 CSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHN 630
Query: 116 N---VTF-RGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+F G W+P Y VS C+L C G +++ + KV+DGT C+ DS V
Sbjct: 631 EFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDSTSV 690
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLI-NTQDLRKGYNDILLIPEG 227
CV G C GCD ++ S K DKC C GNG C KK+ + + GY+DI+ IP G
Sbjct: 691 CVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTC---KKISGSVTSAKPGYHDIITIPTG 747
Query: 228 ATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQG 281
AT I + + + ++LA+++ +GTY LNGDY + + + G + Y +
Sbjct: 748 ATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDYTLSTLEQDIMYKGVVLRYSGSS-- 805
Query: 282 ITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKA-----PLPTQRYSWVHGNF 336
A +++RS P+ EPL + +L + + + +Y+ ++K +PT +WV +
Sbjct: 806 -AALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFS-AWVIEEW 863
Query: 337 SSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSR 396
CS +C G Q R V CR ++ C +KPA+ + C C PQW G WS
Sbjct: 864 GECSKSCELGWQRRLVECR---DINGQPASECAKEVKPASTRPCADHPC-PQWQLGEWSS 919
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CSK CGK G + R ++C + +G V+ + C L PK
Sbjct: 920 CSKTCGK-GYKKRSLKC--LSHDG--GVLSHESCDPLKKPK 955
Score = 66.9 bits (156), Expect = 7e-10
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W +W +CS C +G + R V C +G S C KE K ++PC + CP
Sbjct: 858 WVIEEWGECSKSCELGWQRRLVECRDINGQPA-----SECAKEVKPASTRPCA--DHPCP 910
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL 658
+W WS C+K+CGKG + RS+ CL
Sbjct: 911 -QWQLGEWSSCSKTCGKGYKKRSLKCL 936
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/108 (36%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
WV W CSK C + G + R V C I NG P+ KE KPA C D
Sbjct: 858 WVIEEWGECSKSC-ELGWQRRLVECRDI--NGQPASECAKEV------KPASTRPC-ADH 907
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
CP W + W C K CG G + R + C + G VLS + C K
Sbjct: 908 PCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGG---VLSHESCDPLK 952
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
ES N W I W C K C G Q R V C IN EC++E KP
Sbjct: 847 ESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRD-----INGQPASECAKEVKPAST 901
Query: 501 QPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
+PC PC W + EW+ C TC + R +C++ D V++ C
Sbjct: 902 RPCADHPCP--QWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESC 948
Score = 53.6 bits (123), Expect = 7e-06
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W++ EW C +C + R+ +C +D +S C+ PA PC P Q
Sbjct: 858 WVIEEWGECSKSCELGWQRRLVEC--RDINGQPASECAKEVKPASTRPCADHPCP----Q 911
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDG 600
W +WS CS CG G K R + C DG
Sbjct: 912 WQLGEWSSCSKTCGKGYKKRSLKCLSHDG 940
Score = 42.7 bits (96), Expect = 0.014
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCE--ALG 688
S W W EC+KSC G + R V C G+ S+C K+ P S C + C LG
Sbjct: 856 SAWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPASTRPCADHPCPQWQLG 915
Query: 689 EGS 691
E S
Sbjct: 916 EWS 918
Score = 33.5 bits (73), Expect = 8.4
Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 13/67 (19%)
Query: 638 PWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSDCPKKSLPDSAG-SCNEQSC 684
PW +C+++CG G+++ C GGK + C + PD+ G + E+ C
Sbjct: 567 PWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQC 626
Query: 685 EALGEGS 691
EA E S
Sbjct: 627 EAHNEFS 633
>AF060152-1|AAD48080.1| 950|Homo sapiens METH1 protein protein.
Length = 950
Score = 221 bits (539), Expect = 3e-56
Identities = 140/401 (34%), Positives = 204/401 (50%), Gaps = 37/401 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G +Y SC +DCP+N+ FR EQC +N
Sbjct: 554 CSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHN 613
Query: 116 N---VTF-RGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+F G W+P Y VS C+L C G +++ + KV+DGT C+ DS V
Sbjct: 614 EFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDSTSV 673
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLI-NTQDLRKGYNDILLIPEG 227
CV G C GCD ++ S K DKC C GNG C KK+ + + GY+DI+ IP G
Sbjct: 674 CVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTC---KKISGSVTSAKPGYHDIITIPTG 730
Query: 228 ATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQG 281
AT I + + + ++LA+++ +GTY LNGDY + + + G + Y +
Sbjct: 731 ATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDYTLSTLEQDIMYKGVVLRYSGSS-- 788
Query: 282 ITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKA-----PLPTQRYSWVHGNF 336
A +++RS P+ EPL + +L + + + +Y+ ++K +PT +WV +
Sbjct: 789 -AALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFS-AWVIEEW 846
Query: 337 SSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSR 396
CS +C G Q R V CR ++ C +KPA+ + C C PQW G WS
Sbjct: 847 GECSKSCELGWQRRLVECR---DINGQPASECAKEVKPASTRPCADHPC-PQWQLGEWSS 902
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CSK CGK G + R ++C + +G V+ + C L PK
Sbjct: 903 CSKTCGK-GYKKRSLKC--LSHDG--GVLSHESCDPLKKPK 938
Score = 66.9 bits (156), Expect = 7e-10
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W +W +CS C +G + R V C +G S C KE K ++PC + CP
Sbjct: 841 WVIEEWGECSKSCELGWQRRLVECRDINGQPA-----SECAKEVKPASTRPCA--DHPCP 893
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL 658
+W WS C+K+CGKG + RS+ CL
Sbjct: 894 -QWQLGEWSSCSKTCGKGYKKRSLKCL 919
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/108 (36%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
WV W CSK C + G + R V C I NG P+ KE KPA C D
Sbjct: 841 WVIEEWGECSKSC-ELGWQRRLVECRDI--NGQPASECAKEV------KPASTRPC-ADH 890
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
CP W + W C K CG G + R + C + G VLS + C K
Sbjct: 891 PCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGG---VLSHESCDPLK 935
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
ES N W I W C K C G Q R V C IN EC++E KP
Sbjct: 830 ESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRD-----INGQPASECAKEVKPAST 884
Query: 501 QPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
+PC PC W + EW+ C TC + R +C++ D V++ C
Sbjct: 885 RPCADHPCP--QWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESC 931
Score = 53.6 bits (123), Expect = 7e-06
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W++ EW C +C + R+ +C +D +S C+ PA PC P Q
Sbjct: 841 WVIEEWGECSKSCELGWQRRLVEC--RDINGQPASECAKEVKPASTRPCADHPCP----Q 894
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDG 600
W +WS CS CG G K R + C DG
Sbjct: 895 WQLGEWSSCSKTCGKGYKKRSLKCLSHDG 923
Score = 42.7 bits (96), Expect = 0.014
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCE--ALG 688
S W W EC+KSC G + R V C G+ S+C K+ P S C + C LG
Sbjct: 839 SAWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPASTRPCADHPCPQWQLG 898
Query: 689 EGS 691
E S
Sbjct: 899 EWS 901
Score = 34.3 bits (75), Expect = 4.8
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 619 DSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSD 666
D K + P W PW +C+++CG G+++ C GGK +
Sbjct: 533 DRKHFDTPFHGSWGMW--GPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRS 590
Query: 667 CPKKSLPDSAG-SCNEQSCEALGEGS 691
C + PD+ G + E+ CEA E S
Sbjct: 591 CNLEDCPDNNGKTFREEQCEAHNEFS 616
>AB037767-1|BAA92584.1| 999|Homo sapiens KIAA1346 protein protein.
Length = 999
Score = 221 bits (539), Expect = 3e-56
Identities = 140/401 (34%), Positives = 204/401 (50%), Gaps = 37/401 (9%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G +Y SC +DCP+N+ FR EQC +N
Sbjct: 603 CSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRSCNLEDCPDNNGKTFREEQCEAHN 662
Query: 116 N---VTF-RGKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+F G W+P Y VS C+L C G +++ + KV+DGT C+ DS V
Sbjct: 663 EFSKASFGSGPAVEWIPKYAGVSPKDRCKLICQAKGIGYFFVLQPKVVDGTPCSPDSTSV 722
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLI-NTQDLRKGYNDILLIPEG 227
CV G C GCD ++ S K DKC C GNG C KK+ + + GY+DI+ IP G
Sbjct: 723 CVQGQCVKAGCDRIIDSKKKFDKCGVCGGNGSTC---KKISGSVTSAKPGYHDIITIPTG 779
Query: 228 ATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQG 281
AT I + + + ++LA+++ +GTY LNGDY + + + G + Y +
Sbjct: 780 ATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDYTLSTLEQDIMYKGVVLRYSGSS-- 837
Query: 282 ITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKA-----PLPTQRYSWVHGNF 336
A +++RS P+ EPL + +L + + + +Y+ ++K +PT +WV +
Sbjct: 838 -AALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAIPTFS-AWVIEEW 895
Query: 337 SSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSR 396
CS +C G Q R V CR ++ C +KPA+ + C C PQW G WS
Sbjct: 896 GECSKSCELGWQRRLVECR---DINGQPASECAKEVKPASTRPCADHPC-PQWQLGEWSS 951
Query: 397 CSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
CSK CGK G + R ++C + +G V+ + C L PK
Sbjct: 952 CSKTCGK-GYKKRSLKC--LSHDG--GVLSHESCDPLKKPK 987
Score = 66.9 bits (156), Expect = 7e-10
Identities = 32/87 (36%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W +W +CS C +G + R V C +G S C KE K ++PC + CP
Sbjct: 890 WVIEEWGECSKSCELGWQRRLVECRDINGQPA-----SECAKEVKPASTRPCA--DHPCP 942
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL 658
+W WS C+K+CGKG + RS+ CL
Sbjct: 943 -QWQLGEWSSCSKTCGKGYKKRSLKCL 968
Score = 62.1 bits (144), Expect = 2e-08
Identities = 39/108 (36%), Positives = 47/108 (43%), Gaps = 13/108 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
WV W CSK C + G + R V C I NG P+ KE KPA C D
Sbjct: 890 WVIEEWGECSKSC-ELGWQRRLVECRDI--NGQPASECAKEV------KPASTRPC-ADH 939
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
CP W + W C K CG G + R + C + G VLS + C K
Sbjct: 940 PCPQWQLGEWSSCSKTCGKGYKKRSLKCLSHDGG---VLSHESCDPLK 984
Score = 61.3 bits (142), Expect = 4e-08
Identities = 36/109 (33%), Positives = 47/109 (43%), Gaps = 9/109 (8%)
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
ES N W I W C K C G Q R V C IN EC++E KP
Sbjct: 879 ESFNAIPTFSAWVIEEWGECSKSCELGWQRRLVECRD-----INGQPASECAKEVKPAST 933
Query: 501 QPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFC 548
+PC PC W + EW+ C TC + R +C++ D V++ C
Sbjct: 934 RPCADHPCP--QWQLGEWSSCSKTCGKGYKKRSLKCLSHDGGVLSHESC 980
Score = 53.6 bits (123), Expect = 7e-06
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W++ EW C +C + R+ +C +D +S C+ PA PC P Q
Sbjct: 890 WVIEEWGECSKSCELGWQRRLVEC--RDINGQPASECAKEVKPASTRPCADHPCP----Q 943
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDG 600
W +WS CS CG G K R + C DG
Sbjct: 944 WQLGEWSSCSKTCGKGYKKRSLKCLSHDG 972
Score = 42.7 bits (96), Expect = 0.014
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 3/63 (4%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCE--ALG 688
S W W EC+KSC G + R V C G+ S+C K+ P S C + C LG
Sbjct: 888 SAWVIEEWGECSKSCELGWQRRLVECRDINGQPASECAKEVKPASTRPCADHPCPQWQLG 947
Query: 689 EGS 691
E S
Sbjct: 948 EWS 950
Score = 34.3 bits (75), Expect = 4.8
Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 15/86 (17%)
Query: 619 DSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSD 666
D K + P W PW +C+++CG G+++ C GGK +
Sbjct: 582 DRKHFDTPFHGSWGMW--GPWGDCSRTCGGGVQYTMRECDNPVPKNGGKYCEGKRVRYRS 639
Query: 667 CPKKSLPDSAG-SCNEQSCEALGEGS 691
C + PD+ G + E+ CEA E S
Sbjct: 640 CNLEDCPDNNGKTFREEQCEAHNEFS 665
>AL353895-1|CAI14851.1| 525|Homo sapiens ADAMTS-like 1 protein.
Length = 525
Score = 220 bits (537), Expect = 5e-56
Identities = 138/445 (31%), Positives = 200/445 (44%), Gaps = 52/445 (11%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNV 117
CSRTCGGG + R CL C G + +Y +C DCP + DFRA+QC+ +N+V
Sbjct: 45 CSRTCGGGASYSLRRCLS-----SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDV 99
Query: 118 TFRGKKYRWVPYLK-VSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQP 176
G+ Y W+P PC L C G KV+DGTRC +S D+C+ G+CQ
Sbjct: 100 KHHGQFYEWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQI 159
Query: 177 VGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQ-DLRKGYNDILLIPEGATTIYITE 235
VGCD LGS KED C C G+G C + +Q K + ++ IP G+ I +
Sbjct: 160 VGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVL 219
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDK--LRSLGP 293
P + YL ++ GT G+ + + + + ++++ PDK LR GP
Sbjct: 220 KGPDHLYLETKTLQGT---KGENSLSSTGTFLVDNSSVDFQK------FPDKEILRMAGP 270
Query: 294 INEPLYLSLLLI-DENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDV 352
+ + + + V++ + PI + W +F CSATCGGG Q
Sbjct: 271 LTADFIVKIRNSGSADSTVQFIFYQPI--------IHRWRETDFFPCSATCGGGYQLTSA 322
Query: 353 TCRSREELEVVDEGLC---DDGLKPATN-QTCNTQACP-----------------PQWVP 391
C VV + C + +KP Q CN CP P+W
Sbjct: 323 ECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPASDGYKQIMPYDLYHPLPRWEA 382
Query: 392 GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP 451
W+ CS CG G +SR V C + G + V++ +C + PK + + CN+ CP
Sbjct: 383 TPWTACSSSCG-GGIQSRAVSCVEEDIQGHVTSVEEWKC--MYTPKMPIAQPCNI-FDCP 438
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVC 476
W W PC CG G + R V+C
Sbjct: 439 KWLAQEWSPCTVTCGQGLRYRVVLC 463
Score = 87.0 bits (206), Expect = 6e-16
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 27/190 (14%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVT-KDYRVVNSSFCSYHPT-----PALEEPCDKDKL 565
W +++ C TC + A+C + RVV +C Y+P P L+E C+ D
Sbjct: 301 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQE-CNLDPC 359
Query: 566 PAC----QV----------QWYATQWSKCSVECGVGKKTRRVFCGKFD-GASVMKVDDSN 610
PA Q+ +W AT W+ CS CG G ++R V C + D V V++
Sbjct: 360 PASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWK 419
Query: 611 CPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPK 669
C K ++PC + + CP KW A WS CT +CG+GLR+R V+C+ G C
Sbjct: 420 CMYTPKMPIAQPCNIFD--CP-KWLAQEWSPCTVTCGQGLRYRVVLCIDHRGMHTGGCSP 476
Query: 670 KSLPDSAGSC 679
K+ P C
Sbjct: 477 KTKPHIKEEC 486
Score = 74.1 bits (174), Expect = 5e-12
Identities = 65/238 (27%), Positives = 104/238 (43%), Gaps = 43/238 (18%)
Query: 369 DDGLKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
+ G +T Q Q +W ++ CS CG G + C + +N VV D+
Sbjct: 281 NSGSADSTVQFIFYQPIIHRWRETDFFPCSATCG-GGYQLTSAECYDLRSN---RVVADQ 336
Query: 429 ECF---DLLGPKPALYESCNVDAA-----------------CPTWFISPWKPCDKLCGSG 468
C + + PKP L E CN+D P W +PW C CG G
Sbjct: 337 YCHYYPENIKPKPKLQE-CNLDPCPASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGG 395
Query: 469 QQTRQVVCYQKN-NGRINVLSDDEC--SEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TC 524
Q+R V C +++ G + + + +C + + P+ QPC + C W+ EW+ C TC
Sbjct: 396 IQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPI-AQPCNIFDCP--KWLAQEWSPCTVTC 452
Query: 525 LATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC--------DKDKLPA-CQVQWY 573
+R RV C+ D+R +++ CS P ++E C K+KLP ++ W+
Sbjct: 453 GQGLRYRVVLCI--DHRGMHTGGCSPKTKPHIKEECIVPTPCYKPKEKLPVEAKLPWF 508
Score = 37.1 bits (82), Expect = 0.68
Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 7/67 (10%)
Query: 627 EEKCPSKWYA-APWSECTKSCGKGLRFRSVVCLRG----GK--EFSDCPKKSLPDSAGSC 679
EE W A PWSEC+++CG G + CL G+ + C P AG
Sbjct: 29 EEDRDGLWDAWGPWSECSRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNVDCPPEAGDF 88
Query: 680 NEQSCEA 686
Q C A
Sbjct: 89 RAQQCSA 95
>AY358327-1|AAQ88693.1| 525|Homo sapiens ADAMTSL1 protein.
Length = 525
Score = 219 bits (535), Expect = 9e-56
Identities = 137/445 (30%), Positives = 200/445 (44%), Gaps = 52/445 (11%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNV 117
CSRTCGGG + R CL C G + +Y +C DCP + DFRA+QC+ +N+V
Sbjct: 45 CSRTCGGGASYSLRRCLS-----SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDV 99
Query: 118 TFRGKKYRWVPYLK-VSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQP 176
G+ Y W+P PC L C G KV+DGTRC +S D+C+ G+CQ
Sbjct: 100 KHHGQFYEWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQI 159
Query: 177 VGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQ-DLRKGYNDILLIPEGATTIYITE 235
VGCD LGS KED C C G+G C + +Q K + ++ +P G+ I +
Sbjct: 160 VGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVALPYGSRHIRLVL 219
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDK--LRSLGP 293
P + YL ++ GT G+ + + + + ++++ PDK LR GP
Sbjct: 220 KGPDHLYLETKTLQGT---KGENSLSSTGTFLVDNSSVDFQK------FPDKEILRMAGP 270
Query: 294 INEPLYLSLLLI-DENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDV 352
+ + + + V++ + PI + W +F CSATCGGG Q
Sbjct: 271 LTADFIVKIRNSGSADSTVQFIFYQPI--------IHRWRETDFFPCSATCGGGYQLTSA 322
Query: 353 TCRSREELEVVDEGLC---DDGLKPATN-QTCNTQACP-----------------PQWVP 391
C VV + C + +KP Q CN CP P+W
Sbjct: 323 ECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPASDGYKQIMPYDLYHPLPRWEA 382
Query: 392 GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP 451
W+ CS CG G +SR V C + G + V++ +C + PK + + CN+ CP
Sbjct: 383 TPWTACSSSCG-GGIQSRAVSCVEEDIQGHVTSVEEWKC--MYTPKMPIAQPCNI-FDCP 438
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVC 476
W W PC CG G + R V+C
Sbjct: 439 KWLAQEWSPCTVTCGQGLRYRVVLC 463
Score = 87.0 bits (206), Expect = 6e-16
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 27/190 (14%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVT-KDYRVVNSSFCSYHPT-----PALEEPCDKDKL 565
W +++ C TC + A+C + RVV +C Y+P P L+E C+ D
Sbjct: 301 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQE-CNLDPC 359
Query: 566 PAC----QV----------QWYATQWSKCSVECGVGKKTRRVFCGKFD-GASVMKVDDSN 610
PA Q+ +W AT W+ CS CG G ++R V C + D V V++
Sbjct: 360 PASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWK 419
Query: 611 CPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPK 669
C K ++PC + + CP KW A WS CT +CG+GLR+R V+C+ G C
Sbjct: 420 CMYTPKMPIAQPCNIFD--CP-KWLAQEWSPCTVTCGQGLRYRVVLCIDHRGMHTGGCSP 476
Query: 670 KSLPDSAGSC 679
K+ P C
Sbjct: 477 KTKPHIKEEC 486
Score = 74.1 bits (174), Expect = 5e-12
Identities = 65/238 (27%), Positives = 104/238 (43%), Gaps = 43/238 (18%)
Query: 369 DDGLKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
+ G +T Q Q +W ++ CS CG G + C + +N VV D+
Sbjct: 281 NSGSADSTVQFIFYQPIIHRWRETDFFPCSATCG-GGYQLTSAECYDLRSN---RVVADQ 336
Query: 429 ECF---DLLGPKPALYESCNVDAA-----------------CPTWFISPWKPCDKLCGSG 468
C + + PKP L E CN+D P W +PW C CG G
Sbjct: 337 YCHYYPENIKPKPKLQE-CNLDPCPASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGG 395
Query: 469 QQTRQVVCYQKN-NGRINVLSDDEC--SEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TC 524
Q+R V C +++ G + + + +C + + P+ QPC + C W+ EW+ C TC
Sbjct: 396 IQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPI-AQPCNIFDCP--KWLAQEWSPCTVTC 452
Query: 525 LATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC--------DKDKLPA-CQVQWY 573
+R RV C+ D+R +++ CS P ++E C K+KLP ++ W+
Sbjct: 453 GQGLRYRVVLCI--DHRGMHTGGCSPKTKPHIKEECIVPTPCYKPKEKLPVEAKLPWF 508
Score = 37.1 bits (82), Expect = 0.68
Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 7/67 (10%)
Query: 627 EEKCPSKWYA-APWSECTKSCGKGLRFRSVVCLRG----GK--EFSDCPKKSLPDSAGSC 679
EE W A PWSEC+++CG G + CL G+ + C P AG
Sbjct: 29 EEDRDGLWDAWGPWSECSRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNVDCPPEAGDF 88
Query: 680 NEQSCEA 686
Q C A
Sbjct: 89 RAQQCSA 95
>BC030262-1|AAH30262.1| 439|Homo sapiens ADAMTS-like 1 protein.
Length = 439
Score = 218 bits (532), Expect = 2e-55
Identities = 130/412 (31%), Positives = 190/412 (46%), Gaps = 35/412 (8%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNV 117
CSRTCGGG + R CL C G + +Y +C DCP + DFRA+QC+ +N+V
Sbjct: 45 CSRTCGGGASYSLRRCLS-----SKSCEGRNIRYRTCSNVDCPPEAGDFRAQQCSAHNDV 99
Query: 118 TFRGKKYRWVPYLK-VSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQP 176
G+ Y W+P PC L C G KV+DGTRC +S D+C+ G+CQ
Sbjct: 100 KHHGQFYEWLPVSNDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCYTESLDMCISGLCQI 159
Query: 177 VGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQ-DLRKGYNDILLIPEGATTIYITE 235
VGCD LGS KED C C G+G C + +Q K + ++ IP G+ I +
Sbjct: 160 VGCDHQLGSTVKEDNCGVCNGDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGSRHIRLVL 219
Query: 236 IEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDK--LRSLGP 293
P + YL ++ GT G+ + + + + ++++ PDK LR GP
Sbjct: 220 KGPDHLYLETKTLQGT---KGENSLSSTGTFLVDNSSVDFQK------FPDKEILRMAGP 270
Query: 294 INEPLYLSLLLI-DENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDV 352
+ + + + V++ + PI + W +F CSATCGGG Q
Sbjct: 271 LTADFIVKIRNSGSADSTVQFIFYQPI--------IHRWRETDFFPCSATCGGGYQLTSA 322
Query: 353 TCRSREELEVVDEGLC---DDGLKPATN-QTCNTQACPPQWVPGNWSRCSKRCGKDGTRS 408
C VV + C + +KP Q CN CP +W W+ CS CG G +S
Sbjct: 323 ECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCPARWEATPWTACSSSCG-GGIQS 381
Query: 409 REVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKP 460
R V C + G + V++ +C + PK + + CN+ CP W W P
Sbjct: 382 RAVSCVEEDIQGHVTSVEEWKC--MYTPKMPIAQPCNI-FDCPKWLAQEWSP 430
Score = 68.9 bits (161), Expect = 2e-10
Identities = 42/135 (31%), Positives = 63/135 (46%), Gaps = 7/135 (5%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVT-KDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQ 569
W +++ C TC + A+C + RVV +C Y+P +P + L C
Sbjct: 301 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDPCP 360
Query: 570 VQWYATQWSKCSVECGVGKKTRRVFCGKFD-GASVMKVDDSNCPKEEKYNDSKPCEVPEE 628
+W AT W+ CS CG G ++R V C + D V V++ C K ++PC + +
Sbjct: 361 ARWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPIAQPCNIFD- 419
Query: 629 KCPSKWYAAPWSECT 643
CP KW A WS T
Sbjct: 420 -CP-KWLAQEWSPVT 432
Score = 66.9 bits (156), Expect = 7e-10
Identities = 45/157 (28%), Positives = 72/157 (45%), Gaps = 14/157 (8%)
Query: 369 DDGLKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
+ G +T Q Q +W ++ CS CG G + C + +N VV D+
Sbjct: 281 NSGSADSTVQFIFYQPIIHRWRETDFFPCSATCG-GGYQLTSAECYDLRSN---RVVADQ 336
Query: 429 ECF---DLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKN-NGRI 484
C + + PKP L E CN+D W +PW C CG G Q+R V C +++ G +
Sbjct: 337 YCHYYPENIKPKPKLQE-CNLDPCPARWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHV 395
Query: 485 NVLSDDEC--SEEKPLDRQPCELEPCEGVDWMVSEWT 519
+ + +C + + P+ QPC + C W+ EW+
Sbjct: 396 TSVEEWKCMYTPKMPI-AQPCNIFDCP--KWLAQEWS 429
Score = 57.6 bits (133), Expect = 4e-07
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 4/90 (4%)
Query: 571 QWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC--EVPEE 628
+W T + CS CG G + C +D S V D C + KP E +
Sbjct: 300 RWRETDFFPCSATCGGGYQLTSAEC--YDLRSNRVVADQYCHYYPENIKPKPKLQECNLD 357
Query: 629 KCPSKWYAAPWSECTKSCGKGLRFRSVVCL 658
CP++W A PW+ C+ SCG G++ R+V C+
Sbjct: 358 PCPARWEATPWTACSSSCGGGIQSRAVSCV 387
Score = 37.1 bits (82), Expect = 0.68
Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 7/67 (10%)
Query: 627 EEKCPSKWYA-APWSECTKSCGKGLRFRSVVCLRG----GK--EFSDCPKKSLPDSAGSC 679
EE W A PWSEC+++CG G + CL G+ + C P AG
Sbjct: 29 EEDRDGLWDAWGPWSECSRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNVDCPPEAGDF 88
Query: 680 NEQSCEA 686
Q C A
Sbjct: 89 RAQQCSA 95
>AK023772-1|BAB14673.1| 538|Homo sapiens protein ( Homo sapiens
cDNA FLJ13710 fis, clone PLACE2000373, weakly similar to
F-SPONDIN PRECURSOR. ).
Length = 538
Score = 213 bits (521), Expect = 4e-54
Identities = 125/373 (33%), Positives = 178/373 (47%), Gaps = 19/373 (5%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN 377
P + P ++ ++W + CS TCG G Q C R E E CD +KP
Sbjct: 128 PAPQPPRRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRSTHEEAPESYCDSSMKPTPE 187
Query: 378 QT-CNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP 436
+ CN CP W G WS CSK CG G + R+V C ++ N V C L
Sbjct: 188 EEPCNIFPCPAFWDIGEWSECSKTCGL-GMQHRQVLCRQVYANR-SLTVQPYRCQHL--E 243
Query: 437 KPALYESCNVDAACPTWFI-SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE 495
KP +C + C W I + W C CG GQ+TR V C N G +V+ D+EC+ +
Sbjct: 244 KPETTSTCQLKI-CSEWQIRTDWTSCSVPCGVGQRTRDVKCVS-NIG--DVVDDEECNMK 299
Query: 496 -KPLDRQPCELEPCEGVDWMVSEWTGCDT--CLATVRSRVAQCVTKDYRVVNSSFCSYHP 552
+P D + C++ PC W ++EW+ + C A VR+R C+T + C +
Sbjct: 300 LRPNDIENCDMGPC-AKSWFLTEWSERSSAECGAGVRTRSVVCMTNHVSSLPLEGCGNN- 357
Query: 553 TPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP 612
PA PCD +V+W+A WS+CS+ECG G + R V C + + + +D S C
Sbjct: 358 RPAEATPCDNGPCTG-KVEWFAGSWSQCSIECGSGTQQREVICVRKNADTFEVLDPSECS 416
Query: 613 KEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD-CPKKS 671
EK + C + + C +KW++ WS C+KSC G R R V CL S+ C +
Sbjct: 417 FLEKPPSQQSCHL--KPCGAKWFSTEWSMCSKSCQGGFRVREVRCLSDDMTLSNLCDPQL 474
Query: 672 LPDSAGSCNEQSC 684
P+ SCN Q C
Sbjct: 475 KPEERESCNPQDC 487
Score = 48.8 bits (111), Expect = 2e-04
Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 3/58 (5%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
W +S CS +C GG + R+V C S + + LCD LKP ++CN Q C P+
Sbjct: 436 WFSTEWSMCSKSCQGGFRVREVRCLSDD---MTLSNLCDPQLKPEERESCNPQDCVPE 490
>AB209717-1|BAD92954.1| 418|Homo sapiens ADAMTS-8 precursor variant
protein.
Length = 418
Score = 201 bits (490), Expect = 2e-50
Identities = 126/359 (35%), Positives = 176/359 (49%), Gaps = 38/359 (10%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV R C + P NG C G KY SC T++CP + FR +QC +YN
Sbjct: 67 CSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNA 126
Query: 117 VTFR---GKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCV 170
+ G +WVP Y VS C+L C G + + KVIDGT C ++ +CV
Sbjct: 127 YNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICV 186
Query: 171 DGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATT 230
G C GCD ++ S K DKC C G G++C + + GYNDI+ IP GAT
Sbjct: 187 RGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNY--GYNDIVTIPAGATN 244
Query: 231 IYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQGITA 284
I + + ++ NYLAL++ +G Y LNG+ I + + + G + Y + I
Sbjct: 245 IDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGS---IAT 301
Query: 285 PDKLRSLGPINEPLYLSLLLIDENV---GVEYEYSLP----------IEKAPL----PTQ 327
++L+S P+ EPL + LL + V V+Y + +P E+A P
Sbjct: 302 LERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLL 361
Query: 328 RYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP 386
WV G++S CS+TCG G Q R V CR C+ LKP + C +Q CP
Sbjct: 362 HAQWVLGDWSECSSTCGAGWQRRTVECRDPSSQA---SATCNKALKPEDAKPCESQLCP 417
Score = 43.6 bits (98), Expect = 0.008
Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 7/66 (10%)
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
P QW WS+CS CG G + R V C D +S + C K K D+KPCE
Sbjct: 359 PLLHAQWVLGDWSECSSTCGAGWQRRTVECR--DPSSQA---SATCNKALKPEDAKPCE- 412
Query: 626 PEEKCP 631
+ CP
Sbjct: 413 -SQLCP 417
Score = 43.6 bits (98), Expect = 0.008
Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 1/54 (1%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFS-DCPKKSLPDSAGSCNEQSC 684
++W WSEC+ +CG G + R+V C + S C K P+ A C Q C
Sbjct: 363 AQWVLGDWSECSSTCGAGWQRRTVECRDPSSQASATCNKALKPEDAKPCESQLC 416
Score = 39.5 bits (88), Expect = 0.13
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%)
Query: 317 LPIEKA--PLPTQRYSWVH-GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK 373
LP E+ P P W G + CS TCGGG+Q C+ + E + G G +
Sbjct: 42 LPEEEVERPKPVVDGGWAPWGPWGECSRTCGGGVQFSHRECK---DPEPQNGGRYCLG-R 97
Query: 374 PATNQTCNTQACPPQWVPGNWSRCSK 399
A Q+C+T+ CPP +C K
Sbjct: 98 RAKYQSCHTEECPPDGKSFREQQCEK 123
Score = 38.3 bits (85), Expect = 0.29
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 6/57 (10%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPC 508
W + W C CG+G Q R V C ++ + C++ KP D +PCE + C
Sbjct: 365 WVLGDWSECSSTCGAGWQRRTVECRDPSS-----QASATCNKALKPEDAKPCESQLC 416
Score = 35.5 bits (78), Expect = 2.1
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 17/90 (18%)
Query: 608 DSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK 662
+ +C EE+ KP V P W PW EC+++CG G++F C GG+
Sbjct: 38 EGSCLPEEEVERPKPV-VDGGWAP--W--GPWGECSRTCGGGVQFSHRECKDPEPQNGGR 92
Query: 663 -------EFSDCPKKSLPDSAGSCNEQSCE 685
++ C + P S EQ CE
Sbjct: 93 YCLGRRAKYQSCHTEECPPDGKSFREQQCE 122
Score = 34.3 bits (75), Expect = 4.8
Identities = 14/26 (53%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRC 413
QWV G+WS CS CG G + R V C
Sbjct: 364 QWVLGDWSECSSTCGA-GWQRRTVEC 388
>BC089435-1|AAH89435.1| 918|Homo sapiens ADAMTS8 protein protein.
Length = 918
Score = 200 bits (488), Expect = 4e-50
Identities = 126/359 (35%), Positives = 176/359 (49%), Gaps = 38/359 (10%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV R C + P NG C G KY SC T++CP + FR +QC +YN
Sbjct: 567 CSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNA 626
Query: 117 VTFR---GKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCV 170
+ G +WVP Y VS C+L C G + + KVIDGT C ++ +CV
Sbjct: 627 YNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICV 686
Query: 171 DGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATT 230
G C GCD ++ S K DKC C G G++C + + GYNDI+ IP GAT
Sbjct: 687 RGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNY--GYNDIVTIPAGATN 744
Query: 231 IYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQGITA 284
I + + ++ NYLAL++ +G Y LNG+ I + + + G + Y + I
Sbjct: 745 IDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGS---IAT 801
Query: 285 PDKLRSLGPINEPLYLSLLLIDENV---GVEYEYSLP----------IEKAPL----PTQ 327
++L+S P+ EPL + LL + V V+Y + +P E+A P
Sbjct: 802 LERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLL 861
Query: 328 RYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP 386
WV G++S CS+TCG G Q R V CR C+ LKP + C +Q CP
Sbjct: 862 HAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQA---SATCNKALKPEDAKPCESQLCP 917
Score = 45.2 bits (102), Expect = 0.003
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 7/66 (10%)
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
P QW WS+CS CG G + R V C G + + C K K D+KPCE
Sbjct: 859 PLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQA-----SATCNKALKPEDAKPCE- 912
Query: 626 PEEKCP 631
+ CP
Sbjct: 913 -SQLCP 917
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNEQSC 684
++W WSEC+ +CG G + R+V C G+ + C K P+ A C Q C
Sbjct: 863 AQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLC 916
Score = 39.9 bits (89), Expect = 0.096
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%)
Query: 317 LPIEKA--PLPTQRYSWVH-GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK 373
LP E+ P P W G + CS TCGGG+Q C+ + E + G G +
Sbjct: 542 LPEEEVERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECK---DPEPQNGGRYCLG-R 597
Query: 374 PATNQTCNTQACPPQWVPGNWSRCSK 399
A Q+C+T+ CPP +C K
Sbjct: 598 RAKYQSCHTEECPPDGKSFREQQCEK 623
Score = 38.7 bits (86), Expect = 0.22
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 4/56 (7%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
W + W C CG+G Q R V C + +G+ + + KP D +PCE + C
Sbjct: 865 WVLGDWSECSSTCGAGWQRRTVEC-RDPSGQASATCNKAL---KPEDAKPCESQLC 916
Score = 34.7 bits (76), Expect = 3.6
Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 13/75 (17%)
Query: 624 EVPEEKCPSKWYA-APWSECTKSCGKGLRFRSVVC-----LRGGK-------EFSDCPKK 670
E P+ W PW EC+++CG G++F C GG+ ++ C +
Sbjct: 548 ERPKPVADGGWAPWGPWGECSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTE 607
Query: 671 SLPDSAGSCNEQSCE 685
P S EQ CE
Sbjct: 608 ECPPDGKSFREQQCE 622
Score = 34.3 bits (75), Expect = 4.8
Identities = 14/26 (53%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRC 413
QWV G+WS CS CG G + R V C
Sbjct: 864 QWVLGDWSECSSTCGA-GWQRRTVEC 888
>AF060153-1|AAD48081.1| 890|Homo sapiens METH2 protein protein.
Length = 890
Score = 200 bits (488), Expect = 4e-50
Identities = 126/359 (35%), Positives = 176/359 (49%), Gaps = 38/359 (10%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV R C + P NG C G KY SC T++CP + FR +QC +YN
Sbjct: 539 CSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNA 598
Query: 117 VTFR---GKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCV 170
+ G +WVP Y VS C+L C G + + KVIDGT C ++ +CV
Sbjct: 599 YNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICV 658
Query: 171 DGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATT 230
G C GCD ++ S K DKC C G G++C + + GYNDI+ IP GAT
Sbjct: 659 RGQCVKAGCDHVVDSPRKLDKCGVCGGKGNSCRKVSGSLTPTNY--GYNDIVTIPAGATN 716
Query: 231 IYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQGITA 284
I + + ++ NYLAL++ +G Y LNG+ I + + + G + Y + I
Sbjct: 717 IDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGS---IAT 773
Query: 285 PDKLRSLGPINEPLYLSLLLIDENV---GVEYEYSLP----------IEKAPL----PTQ 327
++L+S P+ EPL + LL + V V+Y + +P E+A P
Sbjct: 774 LERLQSFRPLPEPLTVQLLTVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLL 833
Query: 328 RYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP 386
WV G++S CS+TCG G Q R V CR C+ LKP + C +Q CP
Sbjct: 834 HAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQA---SATCNKALKPEDAKPCESQLCP 889
Score = 45.2 bits (102), Expect = 0.003
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 7/66 (10%)
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
P QW WS+CS CG G + R V C G + + C K K D+KPCE
Sbjct: 831 PLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQA-----SATCNKALKPEDAKPCE- 884
Query: 626 PEEKCP 631
+ CP
Sbjct: 885 -SQLCP 889
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNEQSC 684
++W WSEC+ +CG G + R+V C G+ + C K P+ A C Q C
Sbjct: 835 AQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLC 888
Score = 39.5 bits (88), Expect = 0.13
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%)
Query: 317 LPIEKA--PLPTQRYSWVH-GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK 373
LP E+ P P W G + CS TCGGG+Q C+ + E + G G +
Sbjct: 514 LPEEEVERPKPVVDGGWAPWGPWGECSRTCGGGVQFSHRECK---DPEPQNGGRYCLG-R 569
Query: 374 PATNQTCNTQACPPQWVPGNWSRCSK 399
A Q+C+T+ CPP +C K
Sbjct: 570 RAKYQSCHTEECPPDGKSFREQQCEK 595
Score = 38.7 bits (86), Expect = 0.22
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 4/56 (7%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
W + W C CG+G Q R V C + +G+ + + KP D +PCE + C
Sbjct: 837 WVLGDWSECSSTCGAGWQRRTVEC-RDPSGQASATCNKAL---KPEDAKPCESQLC 888
Score = 35.5 bits (78), Expect = 2.1
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 17/90 (18%)
Query: 608 DSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK 662
+ +C EE+ KP V P W PW EC+++CG G++F C GG+
Sbjct: 510 EGSCLPEEEVERPKPV-VDGGWAP--W--GPWGECSRTCGGGVQFSHRECKDPEPQNGGR 564
Query: 663 -------EFSDCPKKSLPDSAGSCNEQSCE 685
++ C + P S EQ CE
Sbjct: 565 YCLGRRAKYQSCHTEECPPDGKSFREQQCE 594
Score = 34.3 bits (75), Expect = 4.8
Identities = 14/26 (53%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRC 413
QWV G+WS CS CG G + R V C
Sbjct: 836 QWVLGDWSECSSTCGA-GWQRRTVEC 860
>BC094811-1|AAH94811.1| 602|Homo sapiens ADAMTSL4 protein protein.
Length = 602
Score = 199 bits (485), Expect = 1e-49
Identities = 120/382 (31%), Positives = 179/382 (46%), Gaps = 26/382 (6%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PAT 376
P + PL + W S+CSA+CG G+ C SRE E +DE C G + PA+
Sbjct: 183 PHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPAS 242
Query: 377 NQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP 436
+ C+ CPP W G W+ CS+ CG GT+ R+++C + G SV ++ C L P
Sbjct: 243 PEPCHGTPCPPYWEAGEWTSCSRSCG-PGTQHRQLQCRQEFGGGGSSVPPER-CGHL--P 298
Query: 437 KPALYESCNVDAACPTWFI-SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE- 494
+P + +SC + C W + SPW C CG GQ++RQV C NNG + +S+ EC+
Sbjct: 299 RPNITQSCQL-RLCGHWEVGSPWSQCSVRCGRGQRSRQVRCV-GNNG--DEVSEQECASG 354
Query: 495 -EKPLDRQPCELEPCEGVDWMVSEWTG-CDT-CLATVRSRVAQCVTKDYRV------VNS 545
+P R+ C++ PC W S+W+ C C ++ R C+ + +
Sbjct: 355 PPQPPSREACDMGPCT-TAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGA 413
Query: 546 SFCSYHPTPALEEPCDKDKLPACQ--VQWYATQWSKCSVECGVGKKTRRVFCGKFDGASV 603
PT + L C+ +WY W +CS ECG G + R + C G
Sbjct: 414 GTGQSCPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEF 473
Query: 604 MKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKE 663
SNC + +PC+ + C +W++ PWS C++SC G + R V CL +
Sbjct: 474 NVTSPSNCSHLPRPPALQPCQ--GQACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQT 531
Query: 664 FSD-CPKKSLPDSAGSCNEQSC 684
S CP + P CN Q C
Sbjct: 532 LSTRCPPQLRPSRKRPCNSQPC 553
Score = 188 bits (459), Expect = 1e-46
Identities = 143/517 (27%), Positives = 211/517 (40%), Gaps = 42/517 (8%)
Query: 192 CRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGT 251
C C G+ C + + GY IL IP GA + I ++ PS+NYLALR G
Sbjct: 2 CGVCGGDDSTCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGR 61
Query: 252 YYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGV 311
+NG++ +D P S G ++ Y R + + L + GP +P+ + ++ +EN GV
Sbjct: 62 SIINGNWAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIFQEENPGV 121
Query: 312 EYEYSL----PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGL 367
Y+Y + PI + P P + + + ++ +
Sbjct: 122 FYQYVISSPPPILENPTPEPPVPQLQPEILRVEPPLAPAPRPARTPGTLQRQVRIPQ--- 178
Query: 368 CDDGLKPATNQTCNTQACPPQ-WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVD 426
PA P W S CS CGK G C I+ +D
Sbjct: 179 -----MPAPPHPRTPLGSPAAYWKRVGHSACSASCGK-GVWRPIFLC---ISRESGEELD 229
Query: 427 DKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINV 486
++ C P PA E C+ P W W C + CG G Q RQ+ C Q+ G +
Sbjct: 230 ERSCAAGARP-PASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSS 288
Query: 487 LSDDECSE-EKPLDRQPCELEPCEGVDWMV-SEWTGCDT-CLATVRSRVAQCVTKDYRVV 543
+ + C +P Q C+L C W V S W+ C C RSR +CV + V
Sbjct: 289 VPPERCGHLPRPNITQSCQLRLCG--HWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEV 346
Query: 544 NSSFC-SYHPTPALEEPCDKDKLPACQVQWYATQWS-KCSVECGVGKKTRRVFC------ 595
+ C S P P E CD + C W+ + WS KCS ECG G + R V C
Sbjct: 347 SEQECASGPPQPPSREACD---MGPCTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAA 403
Query: 596 -GKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRS 654
G G + S CP + D + C + + +WY PW EC+ CG G + R
Sbjct: 404 LGPGQGEAGAGTGQS-CPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRD 462
Query: 655 VVCL-RGGKEF-----SDCPKKSLPDSAGSCNEQSCE 685
++C+ + G EF S+C P + C Q+C+
Sbjct: 463 IICVSKLGTEFNVTSPSNCSHLPRPPALQPCQGQACQ 499
>BC071852-1|AAH71852.1| 602|Homo sapiens ADAMTSL4 protein protein.
Length = 602
Score = 199 bits (485), Expect = 1e-49
Identities = 120/382 (31%), Positives = 179/382 (46%), Gaps = 26/382 (6%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PAT 376
P + PL + W S+CSA+CG G+ C SRE E +DE C G + PA+
Sbjct: 183 PHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPAS 242
Query: 377 NQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP 436
+ C+ CPP W G W+ CS+ CG GT+ R+++C + G SV ++ C L P
Sbjct: 243 PEPCHGTPCPPYWEAGEWTSCSRSCG-PGTQHRQLQCRQEFGGGGSSVPPER-CGHL--P 298
Query: 437 KPALYESCNVDAACPTWFI-SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE- 494
+P + +SC + C W + SPW C CG GQ++RQV C NNG + +S+ EC+
Sbjct: 299 RPNITQSCQL-RLCGHWEVGSPWSQCSVRCGRGQRSRQVRCV-GNNG--DEVSEQECASG 354
Query: 495 -EKPLDRQPCELEPCEGVDWMVSEWTG-CDT-CLATVRSRVAQCVTKDYRV------VNS 545
+P R+ C++ PC W S+W+ C C ++ R C+ + +
Sbjct: 355 PPQPPSREACDMGPCT-TAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGA 413
Query: 546 SFCSYHPTPALEEPCDKDKLPACQ--VQWYATQWSKCSVECGVGKKTRRVFCGKFDGASV 603
PT + L C+ +WY W +CS ECG G + R + C G
Sbjct: 414 GTGQSCPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEF 473
Query: 604 MKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKE 663
SNC + +PC+ + C +W++ PWS C++SC G + R V CL +
Sbjct: 474 NVTSPSNCSHLPRPPALQPCQ--GQACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQT 531
Query: 664 FSD-CPKKSLPDSAGSCNEQSC 684
S CP + P CN Q C
Sbjct: 532 LSTRCPPQLRPSRKRPCNSQPC 553
Score = 188 bits (459), Expect = 1e-46
Identities = 143/517 (27%), Positives = 211/517 (40%), Gaps = 42/517 (8%)
Query: 192 CRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGT 251
C C G+ C + + GY IL IP GA + I ++ PS+NYLALR G
Sbjct: 2 CGVCGGDDSTCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGR 61
Query: 252 YYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGV 311
+NG++ +D P S G ++ Y R + + L + GP +P+ + ++ +EN GV
Sbjct: 62 SIINGNWAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIFQEENPGV 121
Query: 312 EYEYSL----PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGL 367
Y+Y + PI + P P + + + ++ +
Sbjct: 122 FYQYVISSPPPILENPTPEPPVPQLQPEILRVEPPLAPAPRPARTPGTLQRQVRIPQ--- 178
Query: 368 CDDGLKPATNQTCNTQACPPQ-WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVD 426
PA P W S CS CGK G C I+ +D
Sbjct: 179 -----MPAPPHPRTPLGSPAAYWKRVGHSACSASCGK-GVWRPIFLC---ISRESGEELD 229
Query: 427 DKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINV 486
++ C P PA E C+ P W W C + CG G Q RQ+ C Q+ G +
Sbjct: 230 ERSCAAGARP-PASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSS 288
Query: 487 LSDDECSE-EKPLDRQPCELEPCEGVDWMV-SEWTGCDT-CLATVRSRVAQCVTKDYRVV 543
+ + C +P Q C+L C W V S W+ C C RSR +CV + V
Sbjct: 289 VPPERCGHLPRPNITQSCQLRLCG--HWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEV 346
Query: 544 NSSFC-SYHPTPALEEPCDKDKLPACQVQWYATQWS-KCSVECGVGKKTRRVFC------ 595
+ C S P P E CD + C W+ + WS KCS ECG G + R V C
Sbjct: 347 SEQECASGPPQPPSREACD---MGPCTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAA 403
Query: 596 -GKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRS 654
G G + S CP + D + C + + +WY PW EC+ CG G + R
Sbjct: 404 LGPGQGEAGAGTGQS-CPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRD 462
Query: 655 VVCL-RGGKEF-----SDCPKKSLPDSAGSCNEQSCE 685
++C+ + G EF S+C P + C Q+C+
Sbjct: 463 IICVSKLGTEFNVTSPSNCSHLPRPPALQPCQGQACQ 499
>BC027478-1|AAH27478.1| 424|Homo sapiens ADAMTSL4 protein protein.
Length = 424
Score = 199 bits (485), Expect = 1e-49
Identities = 120/382 (31%), Positives = 179/382 (46%), Gaps = 26/382 (6%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PAT 376
P + PL + W S+CSA+CG G+ C SRE E +DE C G + PA+
Sbjct: 5 PHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPAS 64
Query: 377 NQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP 436
+ C+ CPP W G W+ CS+ CG GT+ R+++C + G SV ++ C L P
Sbjct: 65 PEPCHGTPCPPYWEAGEWTSCSRSCG-PGTQHRQLQCRQEFGGGGSSVPPER-CGHL--P 120
Query: 437 KPALYESCNVDAACPTWFI-SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE- 494
+P + +SC + C W + SPW C CG GQ++RQV C NNG + +S+ EC+
Sbjct: 121 RPNITQSCQL-RLCGHWEVGSPWSQCSVRCGRGQRSRQVRCV-GNNG--DEVSEQECASG 176
Query: 495 -EKPLDRQPCELEPCEGVDWMVSEWTG-CDT-CLATVRSRVAQCVTKDYRV------VNS 545
+P R+ C++ PC W S+W+ C C ++ R C+ + +
Sbjct: 177 PPQPPSREACDMGPCT-TAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGA 235
Query: 546 SFCSYHPTPALEEPCDKDKLPACQ--VQWYATQWSKCSVECGVGKKTRRVFCGKFDGASV 603
PT + L C+ +WY W +CS ECG G + R + C G
Sbjct: 236 GTGQSCPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEF 295
Query: 604 MKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKE 663
SNC + +PC+ + C +W++ PWS C++SC G + R V CL +
Sbjct: 296 NVTSPSNCSHLPRPPALQPCQ--GQACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQT 353
Query: 664 FSD-CPKKSLPDSAGSCNEQSC 684
S CP + P CN Q C
Sbjct: 354 LSTRCPPQLRPSRKRPCNSQPC 375
Score = 134 bits (323), Expect = 4e-30
Identities = 96/315 (30%), Positives = 133/315 (42%), Gaps = 29/315 (9%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W S CS CGK G C I+ +D++ C P PA E C+
Sbjct: 18 WKRVGHSACSASCGK-GVWRPIFLC---ISRESGEELDERSCAAGARP-PASPEPCHGTP 72
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEP 507
P W W C + CG G Q RQ+ C Q+ G + + + C +P Q C+L
Sbjct: 73 CPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSCQLRL 132
Query: 508 CEGVDWMV-SEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFC-SYHPTPALEEPCDKDK 564
C W V S W+ C C RSR +CV + V+ C S P P E CD
Sbjct: 133 CG--HWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACD--- 187
Query: 565 LPACQVQWYATQWS-KCSVECGVGKKTRRVFC-------GKFDGASVMKVDDSNCPKEEK 616
+ C W+ + WS KCS ECG G + R V C G G + S CP +
Sbjct: 188 MGPCTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQS-CPTGSR 246
Query: 617 YNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEF-----SDCPKK 670
D + C + + +WY PW EC+ CG G + R ++C+ + G EF S+C
Sbjct: 247 PPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHL 306
Query: 671 SLPDSAGSCNEQSCE 685
P + C Q+C+
Sbjct: 307 PRPPALQPCQGQACQ 321
>AY358118-1|AAQ88485.1| 1097|Homo sapiens ADAMTS13 protein.
Length = 1097
Score = 198 bits (482), Expect = 2e-49
Identities = 172/660 (26%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F +EQCA+
Sbjct: 64 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSEQCART 123
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 124 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 183
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 184 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 242
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 243 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 301
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 302 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 358
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 359 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 417
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 418 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 475
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 476 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 535
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 536 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 595
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 596 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 655
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 656 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 711
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 416 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 475
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 476 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 529
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 530 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 589
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 590 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 646
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 647 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 703
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 704 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 761
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 762 IQRRRDTCL 770
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 573 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 631
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 632 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 688
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 689 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 747
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 748 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 795
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 630 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 689
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 690 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 745
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 746 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 802
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 401 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 457
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 458 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 504
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 358 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 413
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 414 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 473
Query: 684 CEALGEGS 691
C A E S
Sbjct: 474 CPARWEVS 481
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 26/63 (41%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 744 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 803
Query: 389 WVP 391
P
Sbjct: 804 GTP 806
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 574 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 628
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 629 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 682
>DQ422807-1|ABD72606.1| 1427|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 26/63 (41%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVP 391
P
Sbjct: 1134 GTP 1136
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>AL593848-11|CAI17258.1| 1371|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1371
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 41.5 bits (93), Expect = 0.032
Identities = 22/64 (34%), Positives = 26/64 (40%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVPG 392
G
Sbjct: 1134 GACG 1137
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>AL593848-10|CAI17256.1| 1427|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 26/63 (41%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVP 391
P
Sbjct: 1134 GTP 1136
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>AL593848-9|CAI17257.1| 1340|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1340
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 363 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 422
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 423 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 482
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 483 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 541
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 542 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 600
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 601 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 657
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 658 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 716
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 717 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 774
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 775 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 834
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 835 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 894
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 895 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 954
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 955 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1010
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 715 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 774
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 775 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 828
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 829 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 888
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 889 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 945
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 946 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1002
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1003 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1060
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1061 IQRRRDTCL 1069
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 872 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 930
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 931 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 987
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 988 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1046
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1047 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1094
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 929 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 988
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 989 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1044
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1045 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1101
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 700 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 756
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 757 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 803
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 657 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 712
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 713 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 772
Query: 684 CEALGEGS 691
C A E S
Sbjct: 773 CPARWEVS 780
Score = 41.5 bits (93), Expect = 0.032
Identities = 22/64 (34%), Positives = 26/64 (40%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1043 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1102
Query: 389 WVPG 392
G
Sbjct: 1103 GACG 1106
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 873 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 927
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 928 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 981
>AL158826-24|CAI12850.1| 1427|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1427
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 26/63 (41%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVP 391
P
Sbjct: 1134 GTP 1136
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>AL158826-23|CAI12852.1| 1340|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1340
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 363 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 422
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 423 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 482
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 483 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 541
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 542 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 600
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 601 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 657
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 658 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 716
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 717 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 774
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 775 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 834
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 835 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 894
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 895 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 954
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 955 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1010
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 715 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 774
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 775 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 828
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 829 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 888
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 889 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 945
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 946 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1002
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1003 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1060
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1061 IQRRRDTCL 1069
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 872 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 930
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 931 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 987
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 988 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1046
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1047 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1094
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 929 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 988
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 989 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1044
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1045 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1101
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 700 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 756
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 757 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 803
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 657 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 712
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 713 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 772
Query: 684 CEALGEGS 691
C A E S
Sbjct: 773 CPARWEVS 780
Score = 41.5 bits (93), Expect = 0.032
Identities = 22/64 (34%), Positives = 26/64 (40%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1043 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1102
Query: 389 WVPG 392
G
Sbjct: 1103 GACG 1106
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 873 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 927
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 928 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 981
>AL158826-22|CAI12851.1| 1371|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 13 protein.
Length = 1371
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 41.5 bits (93), Expect = 0.032
Identities = 22/64 (34%), Positives = 26/64 (40%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVPG 392
G
Sbjct: 1134 GACG 1137
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>AJ420810-1|CAD12729.1| 1371|Homo sapiens ADAMTS-13 protein, variant 2
protein.
Length = 1371
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 41.5 bits (93), Expect = 0.032
Identities = 22/64 (34%), Positives = 26/64 (40%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVPG 392
G
Sbjct: 1134 GACG 1137
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>AJ305314-1|CAC83682.1| 1340|Homo sapiens ADAMTS-13 protein protein.
Length = 1340
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 363 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 422
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 423 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 482
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 483 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 541
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 542 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 600
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 601 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 657
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 658 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 716
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 717 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 774
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 775 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 834
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 835 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 894
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 895 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 954
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 955 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1010
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 715 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 774
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 775 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 828
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 829 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 888
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 889 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 945
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 946 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1002
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1003 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1060
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1061 IQRRRDTCL 1069
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 872 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 930
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 931 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 987
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 988 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1046
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1047 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1094
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 929 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 988
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 989 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1044
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1045 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1101
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 700 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 756
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 757 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 803
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 657 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 712
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 713 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 772
Query: 684 CEALGEGS 691
C A E S
Sbjct: 773 CPARWEVS 780
Score = 41.5 bits (93), Expect = 0.032
Identities = 22/64 (34%), Positives = 26/64 (40%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1043 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1102
Query: 389 WVPG 392
G
Sbjct: 1103 GACG 1106
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 873 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 927
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 928 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 981
>AF414401-1|AAL11095.1| 1427|Homo sapiens ADAMTS13 protein.
Length = 1427
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 26/63 (41%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVP 391
P
Sbjct: 1134 GTP 1136
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>AB069698-1|BAB69487.2| 1427|Homo sapiens von Willebrand
factor-cleaving protease protein.
Length = 1427
Score = 196 bits (479), Expect = 5e-49
Identities = 171/660 (25%), Positives = 265/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEW----TGCDTCLATVRSRVAQCVTKDYRVVNSSF-C--SYHP 552
L+ + S W TG + + V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 26/63 (41%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVP 391
P
Sbjct: 1134 GTP 1136
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>AY055376-1|AAL17652.1| 1427|Homo sapiens von Willebrand
factor-cleaving protease precursor protein.
Length = 1427
Score = 196 bits (478), Expect = 7e-49
Identities = 175/660 (26%), Positives = 268/660 (40%), Gaps = 68/660 (10%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 394 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 453
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 454 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 513
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 514 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 572
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 573 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 631
Query: 277 RNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEY-EYSLP----IEKAPLPTQRYSW 331
+ + +++R GP+ E + + G EY + P P P Q + W
Sbjct: 632 LTEDRLPRLEEIRIWGPLQEDADIQ---VYRRYGEEYGNLTRPDITFTYFQPKPRQAWVW 688
Query: 332 VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPPQWV 390
CS +CG G++ + +C + E+V+ C + PA + C + CPP W
Sbjct: 689 AAVR-GPCSVSCGAGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWA 747
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
G++ CS CG G R R VRC + + L ++ + P AL E+CN
Sbjct: 748 VGDFGPCSASCG-GGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVAL-ETCNPQPCP 805
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPC------ 503
W +S C G+G C +G +++ S +EK +PC
Sbjct: 806 ARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCP 865
Query: 504 ----ELEPCEGVDWMVSEWTGCDT--CLATVRSRVA-QC-VTKDYRVVNSSF-C--SYHP 552
L+ + S W T A V + VA C V+ ++ F C S
Sbjct: 866 PGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPVAGSCSVSCGRGLMELRFLCMDSALR 925
Query: 553 TPALEEPCDKDKLP-----ACQVQWYATQW----SKCSVECGVGKKTRRVFC----GKFD 599
P EE C P CQ +W + CSV CG G R ++C G+ D
Sbjct: 926 VPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDD 985
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
G ++ D+ C + + C + E CP +W C+ SCG G RSV C++
Sbjct: 986 GEEILL--DTQCQGLPRPEPQEACSL--EPCPPRWKVMSLGPCSASCGLGTARRSVACVQ 1041
Score = 111 bits (268), Expect = 2e-23
Identities = 102/369 (27%), Positives = 148/369 (40%), Gaps = 55/369 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREE--LEVVDEGLCDDGLK-PATN-QTCNTQACP 386
W G+F CSA+CGGG++ R V C + L+ + C G + PA +TCN Q CP
Sbjct: 746 WAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCP 805
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRC-------EKIITNGLPSVVDDKECFDLLGPKPA 439
+W S C+ G G C E +T G P VD+K L P+P
Sbjct: 806 ARWEVSEPSSCTS-AGGAGLALENETCVPGADGLEAPVTEG-PGSVDEK----LPAPEPC 859
Query: 440 LYESC-----NVDAA-----CPT-W--------FISPWKP----CDKLCGSGQQTRQVVC 476
+ SC ++DA P+ W W P C CG G + +C
Sbjct: 860 VGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPVAGSCSVSCGRGLMELRFLC 919
Query: 477 YQKNNGRINVLSDDECS-EEKPLDRQP-CELEPCEGVDWMVSEWTGCDTCLATVRSRVAQ 534
R+ V ++ C KP R+ C+ PC W +C V R+
Sbjct: 920 MDSAL-RVPV-QEELCGLASKPGSRREVCQAVPCPA-RWQYKLAACSVSCGRGVVRRILY 976
Query: 535 CVTKD-----YRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKK 589
C ++ + C P P +E C L C +W CS CG+G
Sbjct: 977 CARAHGEDDGEEILLDTQCQGLPRPEPQEACS---LEPCPPRWKVMSLGPCSASCGLGTA 1033
Query: 590 TRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG 649
R V C + D ++VD++ C + S PC + + C +W+ W EC+ SCG G
Sbjct: 1034 RRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIAD--CTYRWHVGTWMECSVSCGDG 1091
Query: 650 LRFRSVVCL 658
++ R CL
Sbjct: 1092 IQRRRDTCL 1100
Score = 90.6 bits (215), Expect = 5e-17
Identities = 61/228 (26%), Positives = 94/228 (41%), Gaps = 10/228 (4%)
Query: 338 SCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSR 396
SCS +CG G+ C V E LC KP + + C CP +W +
Sbjct: 903 SCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW-QYKLAA 961
Query: 397 CSKRCGKDGTRSREVRCEKII-TNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS CG+ G R + C + + ++ D +C L P+P E+C+++ P W +
Sbjct: 962 CSVSCGR-GVVRRILYCARAHGEDDGEEILLDTQCQGL--PRPEPQEACSLEPCPPRWKV 1018
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGVDWM 514
PC CG G R V C Q + G+ + + C+ +P PC + C W
Sbjct: 1019 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCT-YRWH 1077
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTKDYRV-VNSSFCSYHPTPALEEPC 560
V W C +C ++ R C+ + V + FC + P P C
Sbjct: 1078 VGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGC 1125
Score = 76.6 bits (180), Expect = 9e-13
Identities = 50/178 (28%), Positives = 79/178 (44%), Gaps = 9/178 (5%)
Query: 337 SSCSATCGGGIQSRDVTC-RSREE---LEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
++CS +CG G+ R + C R+ E E++ + C +P + C+ + CPP+W
Sbjct: 960 AACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVM 1019
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
+ CS CG GT R V C + + G VD+ C L+ P+ ++ C +
Sbjct: 1020 SLGPCSASCGL-GTARRSVACVQ-LDQGQDVEVDEAACAALVRPEASV--PCLIADCTYR 1075
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + W C CG G Q R+ C + V +D KP+ + C PC G
Sbjct: 1076 WHVGTWMECSVSCGDGIQRRRDTCLGP-QAQAPVPADFCQHLPKPVTVRGCWAGPCVG 1132
Score = 49.6 bits (113), Expect = 1e-04
Identities = 28/107 (26%), Positives = 43/107 (40%), Gaps = 3/107 (2%)
Query: 554 PALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK 613
PA E C L C W + CS CG G + R V C + G+ + + + C
Sbjct: 731 PAWPEAC---VLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRA 787
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG 660
+ + CP++W + S CT + G GL + C+ G
Sbjct: 788 GAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG 834
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 12/128 (9%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
W A + CSV CG G + C D A V+ C ++ + P E CP
Sbjct: 688 WAAVR-GPCSVSCGAGLRWVNYSC--LDQARKELVETVQCQGSQQ-PPAWPEACVLEPCP 743
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSA-------GSCNEQS 683
W + C+ SCG GLR R V C+ G P A +CN Q
Sbjct: 744 PYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQP 803
Query: 684 CEALGEGS 691
C A E S
Sbjct: 804 CPARWEVS 811
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 26/63 (41%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
Y W G + CS +CG GIQ R TC + V C KP T + C C Q
Sbjct: 1074 YRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQ 1133
Query: 389 WVP 391
P
Sbjct: 1134 GTP 1136
Score = 40.3 bits (90), Expect = 0.073
Identities = 33/115 (28%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 580 CSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP-CE-VPEEKCPSKWYAA 637
CSV CG G R C D A + V + C K + C+ VP CP++W
Sbjct: 904 CSVSCGRGLMELRFLC--MDSALRVPVQEELCGLASKPGSRREVCQAVP---CPARWQYK 958
Query: 638 PWSECTKSCGKGLRFRSVVCLRG-----GKEF---SDCPKKSLPDSAGSCNEQSC 684
+ C+ SCG+G+ R + C R G+E + C P+ +C+ + C
Sbjct: 959 -LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPC 1012
>BC113874-1|AAI13875.1| 676|Homo sapiens ADAMTS8 protein protein.
Length = 676
Score = 195 bits (476), Expect = 1e-48
Identities = 125/359 (34%), Positives = 175/359 (48%), Gaps = 38/359 (10%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCGGGV R C + P NG C G KY SC T++CP + FR +QC +YN
Sbjct: 325 CSRTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDGKSFREQQCEKYNA 384
Query: 117 VTFR---GKKYRWVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCV 170
+ G +WVP Y VS C+L C G + + KVIDGT C ++ +CV
Sbjct: 385 YNYTDMDGNLLQWVPKYAGVSPRDRCKLFCRARGRSEFKVFEAKVIDGTLCGPETLAICV 444
Query: 171 DGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATT 230
G C GCD ++ S K DKC G G++C + + GYNDI+ IP GAT
Sbjct: 445 RGQCVKAGCDHVVDSPRKLDKCGVRGGKGNSCRKVSGSLTPTNY--GYNDIVTIPAGATN 502
Query: 231 IYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQGITA 284
I + + ++ NYLAL++ +G Y LNG+ I + + + G + Y + I
Sbjct: 503 IDVKQRSHPGVQNDGNYLALKTADGQYLLNGNLAISAIEQDILVKGTILKYSGS---IAT 559
Query: 285 PDKLRSLGPINEPLYLSLLLIDENV---GVEYEYSLP----------IEKAPL----PTQ 327
++L+S P+ EPL + LL + V V+Y + +P E+A P
Sbjct: 560 LERLQSFRPLPEPLTVQLLAVPGEVFPPKVKYTFFVPNDVDFSMQSSKERATTNIIQPLL 619
Query: 328 RYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP 386
WV G++S CS+TCG G Q R V CR C+ LKP + C +Q CP
Sbjct: 620 HAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQA---SATCNKALKPEDAKPCESQLCP 675
Score = 45.2 bits (102), Expect = 0.003
Identities = 24/66 (36%), Positives = 30/66 (45%), Gaps = 7/66 (10%)
Query: 566 PACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEV 625
P QW WS+CS CG G + R V C G + + C K K D+KPCE
Sbjct: 617 PLLHAQWVLGDWSECSSTCGAGWQRRTVECRDPSGQA-----SATCNKALKPEDAKPCE- 670
Query: 626 PEEKCP 631
+ CP
Sbjct: 671 -SQLCP 675
Score = 44.8 bits (101), Expect = 0.003
Identities = 19/54 (35%), Positives = 28/54 (51%), Gaps = 1/54 (1%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNEQSC 684
++W WSEC+ +CG G + R+V C G+ + C K P+ A C Q C
Sbjct: 621 AQWVLGDWSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLC 674
Score = 39.5 bits (88), Expect = 0.13
Identities = 28/86 (32%), Positives = 39/86 (45%), Gaps = 7/86 (8%)
Query: 317 LPIEKA--PLPTQRYSWVH-GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK 373
LP E+ P P W G + CS TCGGG+Q C+ + E + G G +
Sbjct: 300 LPEEEVERPKPVVDGGWAPWGPWGECSRTCGGGVQFSHRECK---DPEPQNGGRYCLG-R 355
Query: 374 PATNQTCNTQACPPQWVPGNWSRCSK 399
A Q+C+T+ CPP +C K
Sbjct: 356 RAKYQSCHTEECPPDGKSFREQQCEK 381
Score = 38.7 bits (86), Expect = 0.22
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 4/56 (7%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
W + W C CG+G Q R V C + +G+ + + KP D +PCE + C
Sbjct: 623 WVLGDWSECSSTCGAGWQRRTVEC-RDPSGQASATCNKAL---KPEDAKPCESQLC 674
Score = 35.5 bits (78), Expect = 2.1
Identities = 26/90 (28%), Positives = 38/90 (42%), Gaps = 17/90 (18%)
Query: 608 DSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGK 662
+ +C EE+ KP V P W PW EC+++CG G++F C GG+
Sbjct: 296 EGSCLPEEEVERPKPV-VDGGWAP--W--GPWGECSRTCGGGVQFSHRECKDPEPQNGGR 350
Query: 663 -------EFSDCPKKSLPDSAGSCNEQSCE 685
++ C + P S EQ CE
Sbjct: 351 YCLGRRAKYQSCHTEECPPDGKSFREQQCE 380
Score = 34.3 bits (75), Expect = 4.8
Identities = 14/26 (53%), Positives = 16/26 (61%), Gaps = 1/26 (3%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRC 413
QWV G+WS CS CG G + R V C
Sbjct: 622 QWVLGDWSECSSTCGA-GWQRRTVEC 646
>AK131551-1|BAD18685.1| 577|Homo sapiens protein ( Homo sapiens
cDNA FLJ16791 fis, clone TBAES2004105, weakly similar
to ADAM-TS 6 precursor (EC 3.4.24.-). ).
Length = 577
Score = 194 bits (473), Expect = 3e-48
Identities = 98/235 (41%), Positives = 131/235 (55%), Gaps = 3/235 (1%)
Query: 84 CTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNVTFRGKKYRWVPYLKV--SKPCELTCM 141
C G +Y C T CPE+S R QCA YNN F G+ Y W P+ +V ++ CEL C
Sbjct: 291 CIGAYRQYKLCNTNVCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQ 350
Query: 142 QHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHN 201
G RFY R EKVIDGT C+ + +CV G C+ +GCD LGS+ DKC C G+
Sbjct: 351 AMGYRFYVRQAEKVIDGTPCDQNGTAICVSGQCKSIGCDDYLGSDKVVDKCGVCGGDNTG 410
Query: 202 CHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID 261
C + GY+ ++ I EGAT I ITE+ SNNYLALRS++G +NG++ ID
Sbjct: 411 CQVVSGVFKHALTSLGYHRVVEISEGATKINITEMYKSNNYLALRSRSGRSIINGNWAID 470
Query: 262 FPRSMTIAGALWNYER-NQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEY 315
P G ++ Y+R N+ TA + + GP NE L + ++ N GV YEY
Sbjct: 471 RPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEY 525
>BX649571-2|CAI18773.1| 951|Homo sapiens ADAMTS-like 2 protein.
Length = 951
Score = 193 bits (470), Expect = 7e-48
Identities = 115/363 (31%), Positives = 155/363 (42%), Gaps = 20/363 (5%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQ 383
P Y W + CSATC G+ S C + +EV D+ CD +P ++ C +
Sbjct: 562 PADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEV-DDSYCDALTRPEPVHEFCAGR 620
Query: 384 ACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYES 443
C P+W +WS CS+ CG +G + R VRC K+++ G S V C +P ++
Sbjct: 621 ECQPRWETSSWSECSRTCG-EGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKT 679
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQ-TRQVVCYQKNNGRINVLSDDECSEEKPLDRQP 502
C A P W +S W C CG TR + C + L D +P+ +
Sbjct: 680 CRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEK-----LCDPNT---RPVGEKN 731
Query: 503 CELEPCEGVDWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C PC+ W VS+W C R+ R C T D RVV S C P PC
Sbjct: 732 CTGPPCDR-QWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCG 790
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
PA W A W +C+ CG G K R V C + C +K +
Sbjct: 791 DKNCPA---HWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEES 847
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNE 681
C E C KWY +PWSECTK+CG G+R R V C +G C P +C+
Sbjct: 848 TCF--ERPC-FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDL 904
Query: 682 QSC 684
Q C
Sbjct: 905 QPC 907
Score = 168 bits (408), Expect = 2e-40
Identities = 103/289 (35%), Positives = 149/289 (51%), Gaps = 23/289 (7%)
Query: 56 TPCSRTCGGGVASQKRICLEI------GPNGEPQCTGGDTKYFSCETQDCPENSLDFRAE 109
T CSR+CGGGV SQ+R CL+ GP G CTG +Y C Q+CP + FR E
Sbjct: 57 TACSRSCGGGVTSQERHCLQQRRKSVPGP-GNRTCTGTSKRYQLCRVQECPPDGRSFREE 115
Query: 110 QCAQYNNVTFRGKKYRWVP-----YLKVS-KPCELTCMQ-HGDRFYYRHKEKVIDGTRCN 162
QC +N+ + G+ ++W P Y+ +S KPC+L C G R + DGT C
Sbjct: 116 QCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQR---QLMVPARDGTSCK 172
Query: 163 -DDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDI 221
D VCV G C+P+GCD +L S DKC C+G+G +C + GY+ +
Sbjct: 173 LTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLV 232
Query: 222 LLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQG 281
IP GA I I E + S + LAL + G Y+ NG+Y +D P++ IAG + Y R
Sbjct: 233 THIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDV 292
Query: 282 I-TAPDKLRSLGPINEPLYLSLLLID-ENVGVEYEYSL---PIEKAPLP 325
T + + + GP N+ L + + + ++ + +EY+L P E P P
Sbjct: 293 YETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQP 341
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
+ W +S C+ TCG G++ RDV C ++ G CD +KP Q C+ Q CP +
Sbjct: 855 FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIV---RG-CDPLVKPVGRQACDLQPCPTE 910
Score = 35.1 bits (77), Expect = 2.7
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP 387
+++CS +CGGG+ S++ C + V G Q C Q CPP
Sbjct: 56 WTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPP 107
>BX649571-1|CAM26559.1| 1060|Homo sapiens ADAMTS-like 2 protein.
Length = 1060
Score = 193 bits (470), Expect = 7e-48
Identities = 115/363 (31%), Positives = 155/363 (42%), Gaps = 20/363 (5%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQ 383
P Y W + CSATC G+ S C + +EV D+ CD +P ++ C +
Sbjct: 671 PADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEV-DDSYCDALTRPEPVHEFCAGR 729
Query: 384 ACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYES 443
C P+W +WS CS+ CG +G + R VRC K+++ G S V C +P ++
Sbjct: 730 ECQPRWETSSWSECSRTCG-EGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKT 788
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQ-TRQVVCYQKNNGRINVLSDDECSEEKPLDRQP 502
C A P W +S W C CG TR + C + L D +P+ +
Sbjct: 789 CRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEK-----LCDPNT---RPVGEKN 840
Query: 503 CELEPCEGVDWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C PC+ W VS+W C R+ R C T D RVV S C P PC
Sbjct: 841 CTGPPCDR-QWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCG 899
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
PA W A W +C+ CG G K R V C + C +K +
Sbjct: 900 DKNCPA---HWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEES 956
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNE 681
C E C KWY +PWSECTK+CG G+R R V C +G C P +C+
Sbjct: 957 TCF--ERPC-FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDL 1013
Query: 682 QSC 684
Q C
Sbjct: 1014 QPC 1016
Score = 168 bits (408), Expect = 2e-40
Identities = 103/289 (35%), Positives = 149/289 (51%), Gaps = 23/289 (7%)
Query: 56 TPCSRTCGGGVASQKRICLEI------GPNGEPQCTGGDTKYFSCETQDCPENSLDFRAE 109
T CSR+CGGGV SQ+R CL+ GP G CTG +Y C Q+CP + FR E
Sbjct: 166 TACSRSCGGGVTSQERHCLQQRRKSVPGP-GNRTCTGTSKRYQLCRVQECPPDGRSFREE 224
Query: 110 QCAQYNNVTFRGKKYRWVP-----YLKVS-KPCELTCMQ-HGDRFYYRHKEKVIDGTRCN 162
QC +N+ + G+ ++W P Y+ +S KPC+L C G R + DGT C
Sbjct: 225 QCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQR---QLMVPARDGTSCK 281
Query: 163 -DDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDI 221
D VCV G C+P+GCD +L S DKC C+G+G +C + GY+ +
Sbjct: 282 LTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLV 341
Query: 222 LLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQG 281
IP GA I I E + S + LAL + G Y+ NG+Y +D P++ IAG + Y R
Sbjct: 342 THIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDV 401
Query: 282 I-TAPDKLRSLGPINEPLYLSLLLID-ENVGVEYEYSL---PIEKAPLP 325
T + + + GP N+ L + + + ++ + +EY+L P E P P
Sbjct: 402 YETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQP 450
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
+ W +S C+ TCG G++ RDV C ++ G CD +KP Q C+ Q CP +
Sbjct: 964 FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIV---RG-CDPLVKPVGRQACDLQPCPTE 1019
Score = 35.1 bits (77), Expect = 2.7
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP 387
+++CS +CGGG+ S++ C + V G Q C Q CPP
Sbjct: 165 WTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPP 216
>BX629352-2|CAI23592.1| 951|Homo sapiens ADAMTS-like 2 protein.
Length = 951
Score = 193 bits (470), Expect = 7e-48
Identities = 115/363 (31%), Positives = 155/363 (42%), Gaps = 20/363 (5%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQ 383
P Y W + CSATC G+ S C + +EV D+ CD +P ++ C +
Sbjct: 562 PADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEV-DDSYCDALTRPEPVHEFCAGR 620
Query: 384 ACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYES 443
C P+W +WS CS+ CG +G + R VRC K+++ G S V C +P ++
Sbjct: 621 ECQPRWETSSWSECSRTCG-EGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKT 679
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQ-TRQVVCYQKNNGRINVLSDDECSEEKPLDRQP 502
C A P W +S W C CG TR + C + L D +P+ +
Sbjct: 680 CRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEK-----LCDPNT---RPVGEKN 731
Query: 503 CELEPCEGVDWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C PC+ W VS+W C R+ R C T D RVV S C P PC
Sbjct: 732 CTGPPCDR-QWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCG 790
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
PA W A W +C+ CG G K R V C + C +K +
Sbjct: 791 DKNCPA---HWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEES 847
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNE 681
C E C KWY +PWSECTK+CG G+R R V C +G C P +C+
Sbjct: 848 TCF--ERPC-FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDL 904
Query: 682 QSC 684
Q C
Sbjct: 905 QPC 907
Score = 168 bits (408), Expect = 2e-40
Identities = 103/289 (35%), Positives = 149/289 (51%), Gaps = 23/289 (7%)
Query: 56 TPCSRTCGGGVASQKRICLEI------GPNGEPQCTGGDTKYFSCETQDCPENSLDFRAE 109
T CSR+CGGGV SQ+R CL+ GP G CTG +Y C Q+CP + FR E
Sbjct: 57 TACSRSCGGGVTSQERHCLQQRRKSVPGP-GNRTCTGTSKRYQLCRVQECPPDGRSFREE 115
Query: 110 QCAQYNNVTFRGKKYRWVP-----YLKVS-KPCELTCMQ-HGDRFYYRHKEKVIDGTRCN 162
QC +N+ + G+ ++W P Y+ +S KPC+L C G R + DGT C
Sbjct: 116 QCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQR---QLMVPARDGTSCK 172
Query: 163 -DDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDI 221
D VCV G C+P+GCD +L S DKC C+G+G +C + GY+ +
Sbjct: 173 LTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLV 232
Query: 222 LLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQG 281
IP GA I I E + S + LAL + G Y+ NG+Y +D P++ IAG + Y R
Sbjct: 233 THIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDV 292
Query: 282 I-TAPDKLRSLGPINEPLYLSLLLID-ENVGVEYEYSL---PIEKAPLP 325
T + + + GP N+ L + + + ++ + +EY+L P E P P
Sbjct: 293 YETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQP 341
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
+ W +S C+ TCG G++ RDV C ++ G CD +KP Q C+ Q CP +
Sbjct: 855 FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIV---RG-CDPLVKPVGRQACDLQPCPTE 910
Score = 35.1 bits (77), Expect = 2.7
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP 387
+++CS +CGGG+ S++ C + V G Q C Q CPP
Sbjct: 56 WTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPP 107
>BX629352-1|CAM28356.1| 1060|Homo sapiens ADAMTS-like 2 protein.
Length = 1060
Score = 193 bits (470), Expect = 7e-48
Identities = 115/363 (31%), Positives = 155/363 (42%), Gaps = 20/363 (5%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQ 383
P Y W + CSATC G+ S C + +EV D+ CD +P ++ C +
Sbjct: 671 PADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEV-DDSYCDALTRPEPVHEFCAGR 729
Query: 384 ACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYES 443
C P+W +WS CS+ CG +G + R VRC K+++ G S V C +P ++
Sbjct: 730 ECQPRWETSSWSECSRTCG-EGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKT 788
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQ-TRQVVCYQKNNGRINVLSDDECSEEKPLDRQP 502
C A P W +S W C CG TR + C + L D +P+ +
Sbjct: 789 CRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEK-----LCDPNT---RPVGEKN 840
Query: 503 CELEPCEGVDWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C PC+ W VS+W C R+ R C T D RVV S C P PC
Sbjct: 841 CTGPPCDR-QWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCG 899
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
PA W A W +C+ CG G K R V C + C +K +
Sbjct: 900 DKNCPA---HWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEES 956
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNE 681
C E C KWY +PWSECTK+CG G+R R V C +G C P +C+
Sbjct: 957 TCF--ERPC-FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDL 1013
Query: 682 QSC 684
Q C
Sbjct: 1014 QPC 1016
Score = 168 bits (408), Expect = 2e-40
Identities = 103/289 (35%), Positives = 149/289 (51%), Gaps = 23/289 (7%)
Query: 56 TPCSRTCGGGVASQKRICLEI------GPNGEPQCTGGDTKYFSCETQDCPENSLDFRAE 109
T CSR+CGGGV SQ+R CL+ GP G CTG +Y C Q+CP + FR E
Sbjct: 166 TACSRSCGGGVTSQERHCLQQRRKSVPGP-GNRTCTGTSKRYQLCRVQECPPDGRSFREE 224
Query: 110 QCAQYNNVTFRGKKYRWVP-----YLKVS-KPCELTCMQ-HGDRFYYRHKEKVIDGTRCN 162
QC +N+ + G+ ++W P Y+ +S KPC+L C G R + DGT C
Sbjct: 225 QCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQR---QLMVPARDGTSCK 281
Query: 163 -DDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDI 221
D VCV G C+P+GCD +L S DKC C+G+G +C + GY+ +
Sbjct: 282 LTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLV 341
Query: 222 LLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQG 281
IP GA I I E + S + LAL + G Y+ NG+Y +D P++ IAG + Y R
Sbjct: 342 THIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDV 401
Query: 282 I-TAPDKLRSLGPINEPLYLSLLLID-ENVGVEYEYSL---PIEKAPLP 325
T + + + GP N+ L + + + ++ + +EY+L P E P P
Sbjct: 402 YETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQP 450
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
+ W +S C+ TCG G++ RDV C ++ G CD +KP Q C+ Q CP +
Sbjct: 964 FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIV---RG-CDPLVKPVGRQACDLQPCPTE 1019
Score = 35.1 bits (77), Expect = 2.7
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP 387
+++CS +CGGG+ S++ C + V G Q C Q CPP
Sbjct: 165 WTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPP 216
>BX324209-2|CAI17317.1| 951|Homo sapiens ADAMTS-like 2 protein.
Length = 951
Score = 193 bits (470), Expect = 7e-48
Identities = 115/363 (31%), Positives = 155/363 (42%), Gaps = 20/363 (5%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQ 383
P Y W + CSATC G+ S C + +EV D+ CD +P ++ C +
Sbjct: 562 PADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEV-DDSYCDALTRPEPVHEFCAGR 620
Query: 384 ACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYES 443
C P+W +WS CS+ CG +G + R VRC K+++ G S V C +P ++
Sbjct: 621 ECQPRWETSSWSECSRTCG-EGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKT 679
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQ-TRQVVCYQKNNGRINVLSDDECSEEKPLDRQP 502
C A P W +S W C CG TR + C + L D +P+ +
Sbjct: 680 CRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEK-----LCDPNT---RPVGEKN 731
Query: 503 CELEPCEGVDWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C PC+ W VS+W C R+ R C T D RVV S C P PC
Sbjct: 732 CTGPPCDR-QWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCG 790
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
PA W A W +C+ CG G K R V C + C +K +
Sbjct: 791 DKNCPA---HWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEES 847
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNE 681
C E C KWY +PWSECTK+CG G+R R V C +G C P +C+
Sbjct: 848 TCF--ERPC-FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDL 904
Query: 682 QSC 684
Q C
Sbjct: 905 QPC 907
Score = 168 bits (408), Expect = 2e-40
Identities = 103/289 (35%), Positives = 149/289 (51%), Gaps = 23/289 (7%)
Query: 56 TPCSRTCGGGVASQKRICLEI------GPNGEPQCTGGDTKYFSCETQDCPENSLDFRAE 109
T CSR+CGGGV SQ+R CL+ GP G CTG +Y C Q+CP + FR E
Sbjct: 57 TACSRSCGGGVTSQERHCLQQRRKSVPGP-GNRTCTGTSKRYQLCRVQECPPDGRSFREE 115
Query: 110 QCAQYNNVTFRGKKYRWVP-----YLKVS-KPCELTCMQ-HGDRFYYRHKEKVIDGTRCN 162
QC +N+ + G+ ++W P Y+ +S KPC+L C G R + DGT C
Sbjct: 116 QCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQR---QLMVPARDGTSCK 172
Query: 163 -DDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDI 221
D VCV G C+P+GCD +L S DKC C+G+G +C + GY+ +
Sbjct: 173 LTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLV 232
Query: 222 LLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQG 281
IP GA I I E + S + LAL + G Y+ NG+Y +D P++ IAG + Y R
Sbjct: 233 THIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDV 292
Query: 282 I-TAPDKLRSLGPINEPLYLSLLLID-ENVGVEYEYSL---PIEKAPLP 325
T + + + GP N+ L + + + ++ + +EY+L P E P P
Sbjct: 293 YETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQP 341
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
+ W +S C+ TCG G++ RDV C ++ G CD +KP Q C+ Q CP +
Sbjct: 855 FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIV---RG-CDPLVKPVGRQACDLQPCPTE 910
Score = 35.1 bits (77), Expect = 2.7
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP 387
+++CS +CGGG+ S++ C + V G Q C Q CPP
Sbjct: 56 WTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPP 107
>BX324209-1|CAM24586.1| 1060|Homo sapiens ADAMTS-like 2 protein.
Length = 1060
Score = 193 bits (470), Expect = 7e-48
Identities = 115/363 (31%), Positives = 155/363 (42%), Gaps = 20/363 (5%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQ 383
P Y W + CSATC G+ S C + +EV D+ CD +P ++ C +
Sbjct: 671 PADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEV-DDSYCDALTRPEPVHEFCAGR 729
Query: 384 ACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYES 443
C P+W +WS CS+ CG +G + R VRC K+++ G S V C +P ++
Sbjct: 730 ECQPRWETSSWSECSRTCG-EGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKT 788
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQ-TRQVVCYQKNNGRINVLSDDECSEEKPLDRQP 502
C A P W +S W C CG TR + C + L D +P+ +
Sbjct: 789 CRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEK-----LCDPNT---RPVGEKN 840
Query: 503 CELEPCEGVDWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C PC+ W VS+W C R+ R C T D RVV S C P PC
Sbjct: 841 CTGPPCDR-QWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCG 899
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
PA W A W +C+ CG G K R V C + C +K +
Sbjct: 900 DKNCPA---HWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEES 956
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNE 681
C E C KWY +PWSECTK+CG G+R R V C +G C P +C+
Sbjct: 957 TCF--ERPC-FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDL 1013
Query: 682 QSC 684
Q C
Sbjct: 1014 QPC 1016
Score = 168 bits (408), Expect = 2e-40
Identities = 103/289 (35%), Positives = 149/289 (51%), Gaps = 23/289 (7%)
Query: 56 TPCSRTCGGGVASQKRICLEI------GPNGEPQCTGGDTKYFSCETQDCPENSLDFRAE 109
T CSR+CGGGV SQ+R CL+ GP G CTG +Y C Q+CP + FR E
Sbjct: 166 TACSRSCGGGVTSQERHCLQQRRKSVPGP-GNRTCTGTSKRYQLCRVQECPPDGRSFREE 224
Query: 110 QCAQYNNVTFRGKKYRWVP-----YLKVS-KPCELTCMQ-HGDRFYYRHKEKVIDGTRCN 162
QC +N+ + G+ ++W P Y+ +S KPC+L C G R + DGT C
Sbjct: 225 QCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQR---QLMVPARDGTSCK 281
Query: 163 -DDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDI 221
D VCV G C+P+GCD +L S DKC C+G+G +C + GY+ +
Sbjct: 282 LTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLV 341
Query: 222 LLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQG 281
IP GA I I E + S + LAL + G Y+ NG+Y +D P++ IAG + Y R
Sbjct: 342 THIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDV 401
Query: 282 I-TAPDKLRSLGPINEPLYLSLLLID-ENVGVEYEYSL---PIEKAPLP 325
T + + + GP N+ L + + + ++ + +EY+L P E P P
Sbjct: 402 YETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQP 450
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
+ W +S C+ TCG G++ RDV C ++ G CD +KP Q C+ Q CP +
Sbjct: 964 FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIV---RG-CDPLVKPVGRQACDLQPCPTE 1019
Score = 35.1 bits (77), Expect = 2.7
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP 387
+++CS +CGGG+ S++ C + V G Q C Q CPP
Sbjct: 165 WTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPP 216
>BC050544-1|AAH50544.1| 951|Homo sapiens ADAMTS-like 2 protein.
Length = 951
Score = 193 bits (470), Expect = 7e-48
Identities = 115/363 (31%), Positives = 155/363 (42%), Gaps = 20/363 (5%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQ 383
P Y W + CSATC G+ S C + +EV D+ CD +P ++ C +
Sbjct: 562 PADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEV-DDSYCDALTRPEPVHEFCAGR 620
Query: 384 ACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYES 443
C P+W +WS CS+ CG +G + R VRC K+++ G S V C +P ++
Sbjct: 621 ECQPRWETSSWSECSRTCG-EGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKT 679
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQ-TRQVVCYQKNNGRINVLSDDECSEEKPLDRQP 502
C A P W +S W C CG TR + C + L D +P+ +
Sbjct: 680 CRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEK-----LCDPNT---RPVGEKN 731
Query: 503 CELEPCEGVDWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C PC+ W VS+W C R+ R C T D RVV S C P PC
Sbjct: 732 CTGPPCDR-QWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCG 790
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
PA W A W +C+ CG G K R V C + C +K +
Sbjct: 791 DKNCPA---HWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEES 847
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNE 681
C E C KWY +PWSECTK+CG G+R R V C +G C P +C+
Sbjct: 848 TCF--ERPC-FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDL 904
Query: 682 QSC 684
Q C
Sbjct: 905 QPC 907
Score = 168 bits (408), Expect = 2e-40
Identities = 103/289 (35%), Positives = 149/289 (51%), Gaps = 23/289 (7%)
Query: 56 TPCSRTCGGGVASQKRICLEI------GPNGEPQCTGGDTKYFSCETQDCPENSLDFRAE 109
T CSR+CGGGV SQ+R CL+ GP G CTG +Y C Q+CP + FR E
Sbjct: 57 TACSRSCGGGVTSQERHCLQQRRKSVPGP-GNRTCTGTSKRYQLCRVQECPPDGRSFREE 115
Query: 110 QCAQYNNVTFRGKKYRWVP-----YLKVS-KPCELTCMQ-HGDRFYYRHKEKVIDGTRCN 162
QC +N+ + G+ ++W P Y+ +S KPC+L C G R + DGT C
Sbjct: 116 QCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQR---QLMVPARDGTSCK 172
Query: 163 -DDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDI 221
D VCV G C+P+GCD +L S DKC C+G+G +C + GY+ +
Sbjct: 173 LTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLV 232
Query: 222 LLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQG 281
IP GA I I E + S + LAL + G Y+ NG+Y +D P++ IAG + Y R
Sbjct: 233 THIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDV 292
Query: 282 I-TAPDKLRSLGPINEPLYLSLLLID-ENVGVEYEYSL---PIEKAPLP 325
T + + + GP N+ L + + + ++ + +EY+L P E P P
Sbjct: 293 YETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQP 341
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
+ W +S C+ TCG G++ RDV C ++ G CD +KP Q C+ Q CP +
Sbjct: 855 FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIV---RG-CDPLVKPVGRQACDLQPCPTE 910
Score = 35.1 bits (77), Expect = 2.7
Identities = 16/52 (30%), Positives = 24/52 (46%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP 387
+++CS +CGGG+ S++ C + V G Q C Q CPP
Sbjct: 56 WTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPP 107
>AB011177-1|BAA25531.2| 1031|Homo sapiens KIAA0605 protein protein.
Length = 1031
Score = 193 bits (470), Expect = 7e-48
Identities = 115/363 (31%), Positives = 155/363 (42%), Gaps = 20/363 (5%)
Query: 325 PTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQ 383
P Y W + CSATC G+ S C + +EV D+ CD +P ++ C +
Sbjct: 642 PADMYRWKLSSHEPCSATCTTGVMSAYAMCVRYDGVEV-DDSYCDALTRPEPVHEFCAGR 700
Query: 384 ACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYES 443
C P+W +WS CS+ CG +G + R VRC K+++ G S V C +P ++
Sbjct: 701 ECQPRWETSSWSECSRTCG-EGYQFRVVRCWKMLSPGFDSSVYSDLCEAAEAVRPEERKT 759
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQ-TRQVVCYQKNNGRINVLSDDECSEEKPLDRQP 502
C A P W +S W C CG TR + C + L D +P+ +
Sbjct: 760 CRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEK-----LCDPNT---RPVGEKN 811
Query: 503 CELEPCEGVDWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C PC+ W VS+W C R+ R C T D RVV S C P PC
Sbjct: 812 CTGPPCDR-QWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCG 870
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
PA W A W +C+ CG G K R V C + C +K +
Sbjct: 871 DKNCPA---HWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEES 927
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNE 681
C E C KWY +PWSECTK+CG G+R R V C +G C P +C+
Sbjct: 928 TCF--ERPC-FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDL 984
Query: 682 QSC 684
Q C
Sbjct: 985 QPC 987
Score = 163 bits (397), Expect = 5e-39
Identities = 102/289 (35%), Positives = 148/289 (51%), Gaps = 23/289 (7%)
Query: 56 TPCSRTCGGGVASQKRICLEI------GPNGEPQCTGGDTKYFSCETQDCPENSLDFRAE 109
T SR+CGGGV SQ+R CL+ GP G CTG +Y C Q+CP + FR E
Sbjct: 137 TAFSRSCGGGVTSQERHCLQQRRKSVPGP-GNRTCTGTSKRYQLCRVQECPPDGRSFREE 195
Query: 110 QCAQYNNVTFRGKKYRWVP-----YLKVS-KPCELTCMQ-HGDRFYYRHKEKVIDGTRCN 162
QC +N+ + G+ ++W P Y+ +S KPC+L C G R + DGT C
Sbjct: 196 QCVSFNSHVYNGRTHQWKPLYPDDYVHISSKPCDLHCTTVDGQR---QLMVPARDGTSCK 252
Query: 163 -DDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDI 221
D VCV G C+P+GCD +L S DKC C+G+G +C + GY+ +
Sbjct: 253 LTDLRGVCVSGKCEPIGCDGVLFSTHTLDKCGICQGDGSSCTHVTGNYRKGNAHLGYSLV 312
Query: 222 LLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQG 281
IP GA I I E + S + LAL + G Y+ NG+Y +D P++ IAG + Y R
Sbjct: 313 THIPAGARDIQIVERKKSADVLALADEAGYYFFNGNYKVDSPKNFNIAGTVVKYRRPMDV 372
Query: 282 I-TAPDKLRSLGPINEPLYLSLLLID-ENVGVEYEYSL---PIEKAPLP 325
T + + + GP N+ L + + + ++ + +EY+L P E P P
Sbjct: 373 YETGIEYIVAQGPTNQGLNVMVWNQNGKSPSITFEYTLLQPPHESRPQP 421
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
+ W +S C+ TCG G++ RDV C ++ G CD +KP Q C+ Q CP +
Sbjct: 935 FKWYTSPWSECTKTCGVGVRMRDVKCYQGTDIV---RG-CDPLVKPVGRQACDLQPCPTE 990
>BX641106-1|CAE46049.1| 321|Homo sapiens hypothetical protein
protein.
Length = 321
Score = 188 bits (458), Expect = 2e-46
Identities = 96/224 (42%), Positives = 127/224 (56%), Gaps = 5/224 (2%)
Query: 84 CTGGDTKYFSCETQDCPENSLDFRAEQCAQYNNVTFRGKKYRWVPYLKV--SKPCELTCM 141
C G +Y C T CPE+S R QCA YNN F G+ Y W P+ +V ++ CEL C
Sbjct: 89 CIGAYRQYKLCNTNVCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQ 148
Query: 142 QHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHN 201
G RFY R EKVIDGT C+ + +CV G C+ +GCD LGS+ DKC C G+
Sbjct: 149 AMGYRFYVRQAEKVIDGTPCDQNGTAICVSGQCKSIGCDDYLGSDKVVDKCGVCGGDNTG 208
Query: 202 CHTTKKLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID 261
C + GY+ ++ IPEGAT I ITE+ SNNYLALRS++G +NG++ ID
Sbjct: 209 CQVVSGVFKHALTSLGYHRVVEIPEGATKINITEMYKSNNYLALRSRSGRSIINGNWAID 268
Query: 262 FPRSMTIAGALWNYER-NQQGITAPDKLRSLGPINEPL--YLSL 302
P G ++ Y+R N+ TA + + GP NE L Y+SL
Sbjct: 269 RPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYVSL 312
>AK131403-1|BAD18550.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ16501 fis, clone FEBRA2006519, weakly similar
to Mus musculus papilin mRNA. ).
Length = 415
Score = 187 bits (455), Expect = 4e-46
Identities = 113/318 (35%), Positives = 164/318 (51%), Gaps = 29/318 (9%)
Query: 147 FYYRHKEKVIDGTRCNDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTK 206
F++ KV DGT C+ + DVC+DGVC+ VGCD LGS A D C C+G+ C K
Sbjct: 71 FFFAMSGKVKDGTPCSPNKNDVCIDGVCELVGCDHELGSKAVSDACGVCKGDNSTCKFYK 130
Query: 207 KLINTQDLRKGYNDILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSM 266
L Q Y ++LIP GA +I I E++ S++YLA+RS + +YL G + ID+P
Sbjct: 131 GLYLNQHKANEYYPVVLIPAGARSIEIQELQVSSSYLAVRSLSQKHYLTGGWSIDWPGEF 190
Query: 267 TIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLP--IEKAPL 324
AG + Y+R+ P++L + GP NE L +L+ +N G+ ++Y+LP + P
Sbjct: 191 PFAGTTFEYQRS---FNRPERLYAPGPTNETLVFEILMQGKNPGIAWKYALPKVMNGTPP 247
Query: 325 PTQR--YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCN 381
T+R Y+W S CS +CGGG + C R++ V+ C KP T + CN
Sbjct: 248 ATKRPAYTWSIVQ-SECSVSCGGGYINVKAIC-LRDQNTQVNSSFCSAKTKPVTEPKICN 305
Query: 382 TQACPPQ--------WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
+ACP W W +C+ CG G ++R V C + G PS C L
Sbjct: 306 RRACPAHPVYNMVAGWYSLPWQQCTVTCG-GGVQTRSVHC---VQQGRPS----SSC--L 355
Query: 434 LGPKPALYESCNVDAACP 451
L KP + +CN + CP
Sbjct: 356 LHQKPPVLRACNTN-FCP 372
Score = 64.1 bits (149), Expect = 5e-09
Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK---EEKYNDSKPCEV-PE 627
W Q S+CSV CG G + C + V S K E K + + C P
Sbjct: 256 WSIVQ-SECSVSCGGGYINVKAICLRDQNTQVNSSFCSAKTKPVTEPKICNRRACPAHPV 314
Query: 628 EKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
+ WY+ PW +CT +CG G++ RSV C++ G+ S C P +CN C A
Sbjct: 315 YNMVAGWYSLPWQQCTVTCGGGVQTRSVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPA 373
Score = 50.4 bits (115), Expect = 7e-05
Identities = 44/139 (31%), Positives = 62/139 (44%), Gaps = 28/139 (20%)
Query: 533 AQCVTKDYRVVNSSFCSYHPTPALE-EPCDKDKLPACQVQ-----WYATQWSKCSVECGV 586
A C+ VNSSFCS P E + C++ PA V WY+ W +C+V CG
Sbjct: 276 AICLRDQNTQVNSSFCSAKTKPVTEPKICNRRACPAHPVYNMVAGWYSLPWQQCTVTCGG 335
Query: 587 GKKTRRVFC---GKFDGA-------SVMKVDDSN-CPKEEKYNDSKPCE-------VPEE 628
G +TR V C G+ + V++ ++N CP EK D + VP+
Sbjct: 336 GVQTRSVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPAPEKREDPSCVDFFNWCHLVPQH 395
Query: 629 -KCPSKWYAAPWSECTKSC 646
C K+Y +C KSC
Sbjct: 396 GVCNHKFYG---KQCCKSC 411
Score = 41.1 bits (92), Expect = 0.042
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 11/123 (8%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRIN----VLSDDECSEEKPLDRQPCELEP 507
TW I C CG G + +C + N ++N +E K +R+ C P
Sbjct: 255 TWSIVQ-SECSVSCGGGYINVKAICLRDQNTQVNSSFCSAKTKPVTEPKICNRRACPAHP 313
Query: 508 CEGV--DWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDK 564
+ W W C TC V++R CV + SS C H P + C+ +
Sbjct: 314 VYNMVAGWYSLPWQQCTVTCGGGVQTRSVHCVQQGR---PSSSCLLHQKPPVLRACNTNF 370
Query: 565 LPA 567
PA
Sbjct: 371 CPA 373
>AY358886-1|AAQ89245.1| 837|Homo sapiens ADAMTS4 protein.
Length = 837
Score = 183 bits (445), Expect = 7e-45
Identities = 113/293 (38%), Positives = 153/293 (52%), Gaps = 22/293 (7%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G T++ SC T+DCP S L FR EQCA YN
Sbjct: 532 CSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYN 591
Query: 116 NVTFRGKKYR----WVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+ T K + WVP Y V+ C+LTC +YY + +V+DGT C+ DS V
Sbjct: 592 HRTDLFKSFPGPMDWVPRYTGVAPQDQCKLTCQARALGYYYVLEPRVVDGTPCSPDSSSV 651
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGA 228
CV G C GCD ++GS K DKC C G+G C +K+ + + R GYN+++ IP GA
Sbjct: 652 CVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSGC--SKQSGSFRKFRYGYNNVVTIPAGA 709
Query: 229 TTIYITEI-EPSNN--YLALRSKNGTYYLNGDYHI-DFPRSMTIAGALWNYERNQQGITA 284
T I + + P + YLAL+ +G+Y LNG+Y + P + + GA+ R A
Sbjct: 710 THILVRQQGNPGHRSIYLALKLPDGSYALNGEYTLMPSPTDVVLPGAV--SLRYSGATAA 767
Query: 285 PDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL----PIEKAPLPTQRYSWVH 333
+ L GP+ +PL L +L+ YS P P PT + W+H
Sbjct: 768 SETLSGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVPRPTPSTPRPTPQ-DWLH 819
Score = 35.5 bits (78), Expect = 2.1
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 13/72 (18%)
Query: 638 PWSECTKSCGKGLRFRSVVCLR-----GGK-------EFSDCPKKSLP-DSAGSCNEQSC 684
PW +C+++CG G++F S C R GGK F C + P SA + E+ C
Sbjct: 528 PWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQC 587
Query: 685 EALGEGSGYFTS 696
A + F S
Sbjct: 588 AAYNHRTDLFKS 599
>AL590714-6|CAH72146.1| 837|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 4 protein.
Length = 837
Score = 183 bits (445), Expect = 7e-45
Identities = 113/293 (38%), Positives = 153/293 (52%), Gaps = 22/293 (7%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G T++ SC T+DCP S L FR EQCA YN
Sbjct: 532 CSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYN 591
Query: 116 NVTFRGKKYR----WVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+ T K + WVP Y V+ C+LTC +YY + +V+DGT C+ DS V
Sbjct: 592 HRTDLFKSFPGPMDWVPRYTGVAPQDQCKLTCQAQALGYYYVLEPRVVDGTPCSPDSSSV 651
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGA 228
CV G C GCD ++GS K DKC C G+G C +K+ + + R GYN+++ IP GA
Sbjct: 652 CVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSGC--SKQSGSFRKFRYGYNNVVTIPAGA 709
Query: 229 TTIYITEI-EPSNN--YLALRSKNGTYYLNGDYHI-DFPRSMTIAGALWNYERNQQGITA 284
T I + + P + YLAL+ +G+Y LNG+Y + P + + GA+ R A
Sbjct: 710 THILVRQQGNPGHRSIYLALKLPDGSYALNGEYTLMPSPTDVVLPGAV--SLRYSGATAA 767
Query: 285 PDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL----PIEKAPLPTQRYSWVH 333
+ L GP+ +PL L +L+ YS P P PT + W+H
Sbjct: 768 SETLSGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVPRPTPSTPRPTPQ-DWLH 819
Score = 35.5 bits (78), Expect = 2.1
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 13/72 (18%)
Query: 638 PWSECTKSCGKGLRFRSVVCLR-----GGK-------EFSDCPKKSLP-DSAGSCNEQSC 684
PW +C+++CG G++F S C R GGK F C + P SA + E+ C
Sbjct: 528 PWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQC 587
Query: 685 EALGEGSGYFTS 696
A + F S
Sbjct: 588 AAYNHRTDLFKS 599
>AF148213-1|AAD41494.1| 837|Homo sapiens aggrecanase-1 protein.
Length = 837
Score = 183 bits (445), Expect = 7e-45
Identities = 113/293 (38%), Positives = 153/293 (52%), Gaps = 22/293 (7%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G T++ SC T+DCP S L FR EQCA YN
Sbjct: 532 CSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYN 591
Query: 116 NVTFRGKKYR----WVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+ T K + WVP Y V+ C+LTC +YY + +V+DGT C+ DS V
Sbjct: 592 HRTDLFKSFPGPMDWVPRYTGVAPQDQCKLTCQARALGYYYVLEPRVVDGTPCSPDSSSV 651
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGA 228
CV G C GCD ++GS K DKC C G+G C +K+ + + R GYN+++ IP GA
Sbjct: 652 CVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSGC--SKQSGSFRKFRYGYNNVVTIPAGA 709
Query: 229 TTIYITEI-EPSNN--YLALRSKNGTYYLNGDYHI-DFPRSMTIAGALWNYERNQQGITA 284
T I + + P + YLAL+ +G+Y LNG+Y + P + + GA+ R A
Sbjct: 710 THILVRQQGNPGHRSIYLALKLPDGSYALNGEYTLMPSPTDVVLPGAV--SLRYSGATAA 767
Query: 285 PDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL----PIEKAPLPTQRYSWVH 333
+ L GP+ +PL L +L+ YS P P PT + W+H
Sbjct: 768 SETLSGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVPRPTPSTPRPTPQ-DWLH 819
Score = 35.5 bits (78), Expect = 2.1
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 13/72 (18%)
Query: 638 PWSECTKSCGKGLRFRSVVCLR-----GGK-------EFSDCPKKSLP-DSAGSCNEQSC 684
PW +C+++CG G++F S C R GGK F C + P SA + E+ C
Sbjct: 528 PWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQC 587
Query: 685 EALGEGSGYFTS 696
A + F S
Sbjct: 588 AAYNHRTDLFKS 599
>AB014588-1|BAA31663.2| 849|Homo sapiens KIAA0688 protein protein.
Length = 849
Score = 183 bits (445), Expect = 7e-45
Identities = 113/293 (38%), Positives = 153/293 (52%), Gaps = 22/293 (7%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G T++ SC T+DCP S L FR EQCA YN
Sbjct: 544 CSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYN 603
Query: 116 NVTFRGKKYR----WVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+ T K + WVP Y V+ C+LTC +YY + +V+DGT C+ DS V
Sbjct: 604 HRTDLFKSFPGPMDWVPRYTGVAPQDQCKLTCQARALGYYYVLEPRVVDGTPCSPDSSSV 663
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGA 228
CV G C GCD ++GS K DKC C G+G C +K+ + + R GYN+++ IP GA
Sbjct: 664 CVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSGC--SKQSGSFRKFRYGYNNVVTIPAGA 721
Query: 229 TTIYITEI-EPSNN--YLALRSKNGTYYLNGDYHI-DFPRSMTIAGALWNYERNQQGITA 284
T I + + P + YLAL+ +G+Y LNG+Y + P + + GA+ R A
Sbjct: 722 THILVRQQGNPGHRSIYLALKLPDGSYALNGEYTLMPSPTDVVLPGAV--SLRYSGATAA 779
Query: 285 PDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL----PIEKAPLPTQRYSWVH 333
+ L GP+ +PL L +L+ YS P P PT + W+H
Sbjct: 780 SETLSGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVPRPTPSTPRPTPQ-DWLH 831
Score = 35.5 bits (78), Expect = 2.1
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 13/72 (18%)
Query: 638 PWSECTKSCGKGLRFRSVVCLR-----GGK-------EFSDCPKKSLP-DSAGSCNEQSC 684
PW +C+++CG G++F S C R GGK F C + P SA + E+ C
Sbjct: 540 PWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQC 599
Query: 685 EALGEGSGYFTS 696
A + F S
Sbjct: 600 AAYNHRTDLFKS 611
>BC040620-1|AAH40620.1| 356|Homo sapiens ADAMTSL5 protein protein.
Length = 356
Score = 182 bits (443), Expect = 1e-44
Identities = 102/269 (37%), Positives = 145/269 (53%), Gaps = 12/269 (4%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN 115
T CS +CG GV+ + R CL + P EP C G +Y C+ DCP ++ FR QCA YN
Sbjct: 45 TRCSSSCGRGVSVRSRRCLRL-PGEEP-CWGDSHEYRLCQLPDCPPGAVPFRDLQCALYN 102
Query: 116 NVTFRG--KKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGV 173
G K Y+WVP+ C+L C+ G FY+ +V+DGT C+ + VCV G
Sbjct: 103 GRPVLGTQKTYQWVPFHGAPNQCDLNCLAEGHAFYHSFG-RVLDGTACSPGAQGVCVAGR 161
Query: 174 CQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYI 233
C GCD +LGS A ED+C +C G +C +++ GY ++ LIPEGA I +
Sbjct: 162 CLSAGCDGLLGSGALEDRCGRCGGANDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRV 221
Query: 234 TEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAP-DKLRSLG 292
S N+LAL +G Y LNG + + P + AG Y R+ T P + L++ G
Sbjct: 222 E--HRSRNHLALMGGDGRYVLNGHWVVSPPGTYEAAGTHVVYTRD----TGPQETLQAAG 275
Query: 293 PINEPLYLSLLLIDENVGVEYEYSLPIEK 321
P + L L +LL + N G+E+E+ LP E+
Sbjct: 276 PTSHDLLLQVLLQEPNPGIEFEFWLPRER 304
Score = 33.5 bits (73), Expect = 8.4
Identities = 13/30 (43%), Positives = 18/30 (60%), Gaps = 1/30 (3%)
Query: 631 PSKWYA-APWSECTKSCGKGLRFRSVVCLR 659
P +W W+ C+ SCG+G+ RS CLR
Sbjct: 35 PGEWTPWVSWTRCSSSCGRGVSVRSRRCLR 64
>AK131571-1|BAD18703.1| 471|Homo sapiens protein ( Homo sapiens
cDNA FLJ16825 fis, clone UTERU2036507, weakly similar
to ADAM-TS 6 precursor (EC 3.4.24.-). ).
Length = 471
Score = 182 bits (442), Expect = 2e-44
Identities = 102/269 (37%), Positives = 145/269 (53%), Gaps = 12/269 (4%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN 115
T CS +CG GV+ + R CL + P EP C G +Y C+ DCP ++ FR QCA YN
Sbjct: 45 TRCSSSCGRGVSVRSRRCLRL-PGEEP-CWGDSHEYRLCQLPDCPPGAVPFRDLQCALYN 102
Query: 116 NVTFRG--KKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGV 173
G K Y+WVP+ C+L C+ G FY+ +V+DGT C+ + VCV G
Sbjct: 103 GRPVLGTQKTYQWVPFHGAPNQCDLNCLAEGHAFYHSFG-RVLDGTACSPGAQGVCVAGR 161
Query: 174 CQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYI 233
C GCD +LGS A ED+C +C G +C +++ GY ++ LIPEGA I +
Sbjct: 162 CLSAGCDGLLGSGALEDRCGRCGGADDSCLFVQRVFRDAGAFAGYWNVTLIPEGARHIRV 221
Query: 234 TEIEPSNNYLALRSKNGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAP-DKLRSLG 292
S N+LAL +G Y LNG + + P + AG Y R+ T P + L++ G
Sbjct: 222 E--HRSRNHLALMGGDGRYVLNGHWVVSPPGTYEAAGTHVVYTRD----TGPQETLQAAG 275
Query: 293 PINEPLYLSLLLIDENVGVEYEYSLPIEK 321
P + L L +LL + N G+E+E+ LP E+
Sbjct: 276 PTSHDLLLQVLLQEPNPGIEFEFWLPRER 304
Score = 33.5 bits (73), Expect = 8.4
Identities = 13/30 (43%), Positives = 18/30 (60%), Gaps = 1/30 (3%)
Query: 631 PSKWYA-APWSECTKSCGKGLRFRSVVCLR 659
P +W W+ C+ SCG+G+ RS CLR
Sbjct: 35 PGEWTPWVSWTRCSSSCGRGVSVRSRRCLR 64
>BC063293-1|AAH63293.1| 837|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 4 protein.
Length = 837
Score = 180 bits (438), Expect = 5e-44
Identities = 111/293 (37%), Positives = 152/293 (51%), Gaps = 22/293 (7%)
Query: 58 CSRTCGGGVASQKRICLE-IGPNGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C + NG C G ++ SC T+DCP S L FR EQCA YN
Sbjct: 532 CSRTCGGGVQFSSRDCTRPVTRNGGKYCEGRRARFRSCNTEDCPTGSALTFREEQCAAYN 591
Query: 116 NVTFRGKKYR----WVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+ T K + WVP Y V+ C+LTC +YY + +V+DGT C+ DS V
Sbjct: 592 HRTDLFKSFPGPMDWVPRYTGVAPQDQCKLTCQAQALGYYYVLEPRVVDGTPCSPDSSSV 651
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGA 228
CV G C GCD ++GS K DKC C G+G C +K+ + + R GYN+++ IP GA
Sbjct: 652 CVQGRCIHAGCDRIIGSKKKFDKCMVCGGDGSGC--SKQSGSFRKFRYGYNNVVTIPAGA 709
Query: 229 TTIYITEI-EPSNN--YLALRSKNGTYYLNGDYHI-DFPRSMTIAGALWNYERNQQGITA 284
T I + + P + YLAL+ +G+Y LNG+Y + P + + GA+ R A
Sbjct: 710 THILVRQQGNPGHRSIYLALKLPDGSYALNGEYTLMPSPTDVVLPGAV--SLRYSGATAA 767
Query: 285 PDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL----PIEKAPLPTQRYSWVH 333
+ L GP+ +PL L +L+ YS P P PT + W+H
Sbjct: 768 SETLSGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVPRPTPSTPRPTPQ-DWLH 819
Score = 35.5 bits (78), Expect = 2.1
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 13/72 (18%)
Query: 638 PWSECTKSCGKGLRFRSVVCLR-----GGK-------EFSDCPKKSLP-DSAGSCNEQSC 684
PW +C+++CG G++F S C R GGK F C + P SA + E+ C
Sbjct: 528 PWGDCSRTCGGGVQFSSRDCTRPVTRNGGKYCEGRRARFRSCNTEDCPTGSALTFREEQC 587
Query: 685 EALGEGSGYFTS 696
A + F S
Sbjct: 588 AAYNHRTDLFKS 599
>BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.
Length = 1509
Score = 180 bits (437), Expect = 7e-44
Identities = 105/298 (35%), Positives = 154/298 (51%), Gaps = 22/298 (7%)
Query: 217 GYNDILLIPEGATTIYITEIEPSNNYLALRSKNGT-YYLNGDYHIDFPRSMTIAGALWNY 275
GY DI LIP+GA I + EIE + N+LA+RS++ YYLNG + I + + +AG ++ Y
Sbjct: 630 GYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQY 689
Query: 276 ERNQQGITAPDKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKAP--LPTQRYSWVH 333
+R +KL + GP NE +++ LL N G++YEY++ + + Q Y W +
Sbjct: 690 DRKGD----LEKLMATGPTNESVWIQLLFQVTNPGIKYEYTIQKDGLDNDVEQQMYFWQY 745
Query: 334 GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQT-CNTQACPPQWVPG 392
G+++ CS TCG GI+ + C + +V CD +P Q C+ +ACPP+W G
Sbjct: 746 GHWTECSVTCGTGIRRQTAHCIKKGR-GMVKATFCDPETQPNGRQKKCHEKACPPRWWAG 804
Query: 393 NWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT 452
W CS CG G + R V C + + + + +C LL PK L SCN D CP+
Sbjct: 805 EWEACSATCGPHGEKKRTVLCIQTMVSD-EQALPPTDCQHLLKPKTLL--SCNRDILCPS 861
Query: 453 -WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPCELEPC 508
W + W C CG G + R V C KN+ D+ C KP R C L+ C
Sbjct: 862 DWTVGNWSECSVSCGGGVRIRSVTC-AKNH-------DEPCDVTRKPNSRALCGLQQC 911
Score = 103 bits (247), Expect = 7e-21
Identities = 57/174 (32%), Positives = 80/174 (45%), Gaps = 7/174 (4%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQ 571
W WT C TC +R + A C+ K +V ++FC P + +K AC +
Sbjct: 743 WQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKCHEK--ACPPR 800
Query: 572 WYATQWSKCSVECGV-GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W+A +W CS CG G+K R V C + + + ++C K C + C
Sbjct: 801 WWAGEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCN-RDILC 859
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSC 684
PS W WSEC+ SCG G+R RSV C + E D +K P+S C Q C
Sbjct: 860 PSDWTVGNWSECSVSCGGGVRIRSVTCAKNHDEPCDVTRK--PNSRALCGLQQC 911
Score = 96.3 bits (229), Expect = 1e-18
Identities = 68/236 (28%), Positives = 98/236 (41%), Gaps = 28/236 (11%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W+ GN+S CS TCG G R V C ++ + + C +P + C+ + C W
Sbjct: 1232 WIVGNWSECSTTCGLGAYWRRVECSTQMDSD------CAAIQRPDPAKRCHLRPCAG-WK 1284
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
GNWS+CS+ C G + RE++C + + + C L G P L SCN + C
Sbjct: 1285 VGNWSKCSRNCS-GGFKIREIQC---VDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEP-C 1339
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
W + PW C + CG G Q R V C G L D ++P C C
Sbjct: 1340 EAWQVEPWSQCSRSCGGGVQERGVFC---PGG----LCD---WTKRPTSTMSCNEHLC-- 1387
Query: 511 VDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRVV---NSSFCSYHPTPALEEPCDK 562
W W C T C + R QCV + + C + P P + C++
Sbjct: 1388 CHWATGNWDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQ 1443
Score = 95.5 bits (227), Expect = 2e-18
Identities = 71/244 (29%), Positives = 101/244 (41%), Gaps = 39/244 (15%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCEGV 511
W + W C CG G R+V C + D +C+ ++P + C L PC G
Sbjct: 1232 WIVGNWSECSTTCGLGAYWRRVEC--------STQMDSDCAAIQRPDPAKRCHLRPCAG- 1282
Query: 512 DWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFCSYHP--TPALEEPCDKDKLPA 567
W V W+ C C + R QCV ++D+R + C + P L C+ + A
Sbjct: 1283 -WKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEA 1341
Query: 568 CQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPE 627
QV+ WS+CS CG G + R VFC C ++ + C E
Sbjct: 1342 WQVE----PWSQCSRSCGGGVQERGVFC-----------PGGLCDWTKRPTSTMSCN--E 1384
Query: 628 EKCPSKWYAAPWSECTKSCGKGLRFRSVVCL--RGGK-EFSD---CPKKSLPDSAGSCNE 681
C W W C+ SCG G + R+V C+ G K E D C K P CN+
Sbjct: 1385 HLC-CHWATGNWDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQ 1443
Query: 682 QSCE 685
Q+C+
Sbjct: 1444 QACK 1447
Score = 83.4 bits (197), Expect = 8e-15
Identities = 62/237 (26%), Positives = 87/237 (36%), Gaps = 29/237 (12%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W+ GNWS CS CG G R V C S D +C + P PA + C++
Sbjct: 1232 WIVGNWSECSTTCGL-GAYWRRVEC---------STQMDSDCAAIQRPDPA--KRCHL-R 1278
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGR-INVLSDDECSEEKPLDRQPCELEP 507
C W + W C + C G + R++ C + R + + P C EP
Sbjct: 1279 PCAGWKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEP 1338
Query: 508 CEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLP 566
CE W V W+ C +C V+ R C C + P C++
Sbjct: 1339 CEA--WQVEPWSQCSRSCGGGVQERGVFCP--------GGLCDWTKRPTSTMSCNEHL-- 1386
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C W W CS CG G + R V C +G D C + + + K C
Sbjct: 1387 CCH--WATGNWDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKC 1441
Score = 70.5 bits (165), Expect = 6e-11
Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 14/131 (10%)
Query: 318 PIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN 377
P+ + P +W +S CS +CGGG+Q R V C GLCD +P +
Sbjct: 1329 PLSMSCNPEPCEAWQVEPWSQCSRSCGGGVQERGVFCPG---------GLCDWTKRPTST 1379
Query: 378 QTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPK 437
+CN C W GNW CS CG G + R V+C + + G D +C P+
Sbjct: 1380 MSCNEHLC-CHWATGNWDLCSTSCG-GGFQKRTVQC--VPSEG-NKTEDQDQCLCDHKPR 1434
Query: 438 PALYESCNVDA 448
P ++ CN A
Sbjct: 1435 PPEFKKCNQQA 1445
Score = 63.7 bits (148), Expect = 7e-09
Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG GV S +R+C P G CTG +Y C C + FR QC++++
Sbjct: 554 CSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTFRQMQCSEFDT 613
Query: 117 VTFRGKKYRWVP 128
V ++ + Y W P
Sbjct: 614 VPYKNELYHWFP 625
Score = 53.6 bits (123), Expect = 7e-06
Identities = 25/57 (43%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSRE--ELEVVDEGLCDDGLKPATNQTCNTQAC 385
W GN+ CS +CGGG Q R V C E + E D+ LCD +P + CN QAC
Sbjct: 1390 WATGNWDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQQAC 1446
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP 386
W GN+S CS +CGGG++ R VTC DE CD KP + C Q CP
Sbjct: 863 WTVGNWSECSVSCGGGVRIRSVTCAKNH-----DEP-CDVTRKPNSRALCGLQQCP 912
>AY044847-1|AAL02262.1| 837|Homo sapiens aggrecanase 1 protein.
Length = 837
Score = 180 bits (437), Expect = 7e-44
Identities = 112/293 (38%), Positives = 152/293 (51%), Gaps = 22/293 (7%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENS-LDFRAEQCAQYN 115
CSRTCGGGV R C P NG C G T++ SC T+DCP S L FR EQCA YN
Sbjct: 532 CSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYN 591
Query: 116 NVTFRGKKYR----WVP-YLKVSKP--CELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDV 168
+ T K + WVP Y V+ C+LTC +YY + +V+DGT C+ DS V
Sbjct: 592 HRTDLFKSFPGPMDWVPRYTGVAPQDQCKLTCQAQALGYYYVLEPRVVDGTPCSPDSSSV 651
Query: 169 CVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGA 228
CV G C GCD ++GS K DKC C G+ C +K+ + + R GYN+++ IP GA
Sbjct: 652 CVQGRCIHAGCDRIIGSKKKFDKCMVCGGDRSGC--SKQSGSFRKFRYGYNNVVTIPAGA 709
Query: 229 TTIYITEI-EPSNN--YLALRSKNGTYYLNGDYHI-DFPRSMTIAGALWNYERNQQGITA 284
T I + + P + YLAL+ +G+Y LNG+Y + P + + GA+ R A
Sbjct: 710 THILVRQQGNPGHRSIYLALKLPDGSYALNGEYTLMPSPTDVVLPGAV--SLRYSGATAA 767
Query: 285 PDKLRSLGPINEPLYLSLLLIDENVGVEYEYSL----PIEKAPLPTQRYSWVH 333
+ L GP+ +PL L +L+ YS P P PT + W+H
Sbjct: 768 SETLSGHGPLAQPLTLQVLVAGNPQDTRLRYSFFVPRPTPSTPRPTPQ-DWLH 819
Score = 35.5 bits (78), Expect = 2.1
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 13/72 (18%)
Query: 638 PWSECTKSCGKGLRFRSVVCLR-----GGK-------EFSDCPKKSLP-DSAGSCNEQSC 684
PW +C+++CG G++F S C R GGK F C + P SA + E+ C
Sbjct: 528 PWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQC 587
Query: 685 EALGEGSGYFTS 696
A + F S
Sbjct: 588 AAYNHRTDLFKS 599
>BC109114-1|AAI09115.1| 950|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 15 protein.
Length = 950
Score = 173 bits (421), Expect = 6e-42
Identities = 133/400 (33%), Positives = 183/400 (45%), Gaps = 49/400 (12%)
Query: 57 PCSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSL--DFRAEQCAQ 113
PCSRTCGGGV +R C P NG C G KY SC + CP ++ FR EQC
Sbjct: 527 PCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEA 586
Query: 114 YNNVTFRGKKYR----WVP-YLKVSK--PCELTCMQHGDRFYYRHKEKVIDGTRCNDDSF 166
+N + WVP Y VS C+L C +G ++Y KV+DGT C+ DS
Sbjct: 587 FNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRANGTGYFYVLAPKVVDGTLCSPDST 646
Query: 167 DVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPE 226
VCV G C GCD LGS + DKC C G+ +C L T+ + GYN ++ IP
Sbjct: 647 SVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGDNKSCKKVTGLF-TKPMH-GYNFVVAIPA 704
Query: 227 GATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQ 280
GA++I I + + +NYLAL++ G Y LNG + + R + + G+L Y
Sbjct: 705 GASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTG- 763
Query: 281 GITAPDKLRSLGPINEPLYLSLLLIDENV--GVEYEYSLPIE------KAPLPTQRYSWV 332
TA + L++ PI EPL + +L + + V Y + LP E P + S +
Sbjct: 764 --TAVESLQASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSSHPKDPRGPSVL 821
Query: 333 HGNFSSCS------------ATCGGGIQSRDVTCRSREELEVVD-EGLCDDGLKP---AT 376
H + S S G +C S + VD G P A
Sbjct: 822 HNSVLSLSNQVEQPDDRPPARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAA 881
Query: 377 NQTCNTQACP---PQWVPGNWSRCSKRCGKDGTRSREVRC 413
++ TQAC P W WS CSK CG+ G + R ++C
Sbjct: 882 HRPVETQACGEPCPTWELSAWSPCSKSCGR-GFQRRSLKC 920
Score = 71.7 bits (168), Expect = 3e-11
Identities = 42/124 (33%), Positives = 56/124 (45%), Gaps = 14/124 (11%)
Query: 386 PPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCN 445
P +WV G+W CS CG G + R V C D +P ++C
Sbjct: 840 PARWVAGSWGPCSASCGS-GLQKRAVDCRGSAGQRTVPACDAAH-------RPVETQACG 891
Query: 446 VDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPCE 504
CPTW +S W PC K CG G Q R + C + GR+ L+ D+C+ KP + C
Sbjct: 892 --EPCPTWELSAWSPCSKSCGRGFQRRSLKCV-GHGGRL--LARDQCNLHRKPQELDFCV 946
Query: 505 LEPC 508
L PC
Sbjct: 947 LRPC 950
Score = 60.9 bits (141), Expect = 5e-08
Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 18/133 (13%)
Query: 556 LEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC-GKFDGASVMKVDDSNCPKE 614
+E+P D+ PA +W A W CS CG G + R V C G +V D ++ P E
Sbjct: 832 VEQPDDRP--PA---RWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVE 886
Query: 615 EKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFS--DCPKKS 671
++ C P CP+ W + WS C+KSCG+G + RS+ C+ GG+ + C
Sbjct: 887 -----TQACGEP---CPT-WELSAWSPCSKSCGRGFQRRSLKCVGHGGRLLARDQCNLHR 937
Query: 672 LPDSAGSCNEQSC 684
P C + C
Sbjct: 938 KPQELDFCVLRPC 950
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC--LRGGKEFSDCPKKSLPDSAG 677
S E P+++ P++W A W C+ SCG GL+ R+V C G + C P
Sbjct: 829 SNQVEQPDDRPPARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVETQ 888
Query: 678 SCNE 681
+C E
Sbjct: 889 ACGE 892
>AJ315733-1|CAC86014.1| 950|Homo sapiens metalloprotease
disintegrin 15 with thrombospondin domains protein.
Length = 950
Score = 173 bits (421), Expect = 6e-42
Identities = 133/400 (33%), Positives = 183/400 (45%), Gaps = 49/400 (12%)
Query: 57 PCSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSL--DFRAEQCAQ 113
PCSRTCGGGV +R C P NG C G KY SC + CP ++ FR EQC
Sbjct: 527 PCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEA 586
Query: 114 YNNVTFRGKKYR----WVP-YLKVSK--PCELTCMQHGDRFYYRHKEKVIDGTRCNDDSF 166
+N + WVP Y VS C+L C +G ++Y KV+DGT C+ DS
Sbjct: 587 FNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRANGTGYFYVLAPKVVDGTLCSPDST 646
Query: 167 DVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPE 226
VCV G C GCD LGS + DKC C G+ +C L T+ + GYN ++ IP
Sbjct: 647 SVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGDNKSCKKVTGLF-TKPMH-GYNFVVAIPA 704
Query: 227 GATTIYITE-----IEPSNNYLALRSKNGTYYLNGDYHID-FPRSMTIAGALWNYERNQQ 280
GA++I I + + +NYLAL++ G Y LNG + + R + + G+L Y
Sbjct: 705 GASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTG- 763
Query: 281 GITAPDKLRSLGPINEPLYLSLLLIDENV--GVEYEYSLPIE------KAPLPTQRYSWV 332
TA + L++ PI EPL + +L + + V Y + LP E P + S +
Sbjct: 764 --TAVESLQASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSSHPKDPRGPSVL 821
Query: 333 HGNFSSCS------------ATCGGGIQSRDVTCRSREELEVVD-EGLCDDGLKP---AT 376
H + S S G +C S + VD G P A
Sbjct: 822 HNSVLSLSNQVEQPDDRPPARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAA 881
Query: 377 NQTCNTQACP---PQWVPGNWSRCSKRCGKDGTRSREVRC 413
++ TQAC P W WS CSK CG+ G + R ++C
Sbjct: 882 HRPVETQACGEPCPTWELSAWSPCSKSCGR-GFQRRSLKC 920
Score = 71.7 bits (168), Expect = 3e-11
Identities = 42/124 (33%), Positives = 56/124 (45%), Gaps = 14/124 (11%)
Query: 386 PPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCN 445
P +WV G+W CS CG G + R V C D +P ++C
Sbjct: 840 PARWVAGSWGPCSASCGS-GLQKRAVDCRGSAGQRTVPACDAAH-------RPVETQACG 891
Query: 446 VDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPCE 504
CPTW +S W PC K CG G Q R + C + GR+ L+ D+C+ KP + C
Sbjct: 892 --EPCPTWELSAWSPCSKSCGRGFQRRSLKCV-GHGGRL--LARDQCNLHRKPQELDFCV 946
Query: 505 LEPC 508
L PC
Sbjct: 947 LRPC 950
Score = 60.9 bits (141), Expect = 5e-08
Identities = 43/133 (32%), Positives = 63/133 (47%), Gaps = 18/133 (13%)
Query: 556 LEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC-GKFDGASVMKVDDSNCPKE 614
+E+P D+ PA +W A W CS CG G + R V C G +V D ++ P E
Sbjct: 832 VEQPDDRP--PA---RWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVE 886
Query: 615 EKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFS--DCPKKS 671
++ C P CP+ W + WS C+KSCG+G + RS+ C+ GG+ + C
Sbjct: 887 -----TQACGEP---CPT-WELSAWSPCSKSCGRGFQRRSLKCVGHGGRLLARDQCNLHR 937
Query: 672 LPDSAGSCNEQSC 684
P C + C
Sbjct: 938 KPQELDFCVLRPC 950
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 2/64 (3%)
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC--LRGGKEFSDCPKKSLPDSAG 677
S E P+++ P++W A W C+ SCG GL+ R+V C G + C P
Sbjct: 829 SNQVEQPDDRPPARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVETQ 888
Query: 678 SCNE 681
+C E
Sbjct: 889 ACGE 892
>AF140675-1|AAD56358.1| 997|Homo sapiens zinc metalloprotease
ADAMTS7 protein.
Length = 997
Score = 173 bits (421), Expect = 6e-42
Identities = 90/251 (35%), Positives = 137/251 (54%), Gaps = 13/251 (5%)
Query: 58 CSRTCGGGVASQKRICLEIGPNGEPQ-CTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CG GV S +R C + P + + C G ++ C Q CP FR QC+ ++
Sbjct: 550 CSRSCGMGVQSAERQCTQPTPKYKGRYCVGERKRFRLCNLQACPAGRPSFRHVQCSHFDA 609
Query: 117 VTFRGKKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCND--DSFDVCVDGVC 174
+ ++G+ + WVP + PCEL C + F + ++ V+DGT C S D+C++G+C
Sbjct: 610 MLYKGQLHTWVPVVNDVNPCELHCRPANEYFAKKLRDAVVDGTPCYQVRASRDLCINGIC 669
Query: 175 QPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYIT 234
+ VGCD + S A ED+C C GNG CHT + GY D+ LIP GA I I
Sbjct: 670 KNVGCDFEIDSGAMEDRCGVCHGNGSTCHTVSGTFEEAE-GLGYVDVGLIPAGAREIRIQ 728
Query: 235 EIEPSNNYLALRSKN-GTYYLNGDYHIDFPRSMTIAGALWNYER--NQQGITAPDKLRSL 291
E+ + N+LALRS++ Y+LNG + I + +AG + Y R N + +T+P
Sbjct: 729 EVAEAANFLALRSEDPEKYFLNGGWTIQWNGDYQVAGTTFTYARRGNWENLTSP------ 782
Query: 292 GPINEPLYLSL 302
GP EP+++ +
Sbjct: 783 GPTKEPVWIQV 793
Score = 39.1 bits (87), Expect = 0.17
Identities = 21/59 (35%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 302 LLLIDENVGVEYEYSLPIEKA---PLPTQRYSWVHGNFSSCSATCGGGIQ--SRDVTCR 355
LL + N GV YEY++ E +P +SW +G ++ C+ TCG G + TCR
Sbjct: 887 LLFQESNPGVHYEYTIHREAGGHDEVPPPVFSWHYGPWTKCTVTCGRGEKWGRHSPTCR 945
>AK092324-1|BAC03862.1| 296|Homo sapiens protein ( Homo sapiens
cDNA FLJ35005 fis, clone OCBBF2012001, weakly similar to
Homo sapiens zinc metalloprotease ADAMTS6 (ADAMTS6)
mRNA. ).
Length = 296
Score = 166 bits (404), Expect = 7e-40
Identities = 78/189 (41%), Positives = 108/189 (57%), Gaps = 7/189 (3%)
Query: 54 DVTPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQ 113
D + CSRTCGGG + R CL G N C G + +Y +C DCP ++ DFRA+QC+
Sbjct: 83 DWSDCSRTCGGGASYSLRRCLT-GRN----CEGQNIRYKTCSNHDCPPDAEDFRAQQCSA 137
Query: 114 YNNVTFRGKKYRWVP-YLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDG 172
YN+V ++G Y W+P Y + PC L C G KV+DGTRCN DS D+C+ G
Sbjct: 138 YNDVQYQGHYYEWLPRYNDPAAPCALKCHAQGQNLVVELAPKVLDGTRCNTDSLDMCISG 197
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQ-DLRKGYNDILLIPEGATTI 231
+CQ VGCD LGSNAKED C C G+G C + + K +++ +P G+ ++
Sbjct: 198 ICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSV 257
Query: 232 YITEIEPSN 240
IT P++
Sbjct: 258 RITVKGPAH 266
>AF141293-1|AAF02493.1| 518|Homo sapiens ADAMTS5 protein protein.
Length = 518
Score = 164 bits (399), Expect = 3e-39
Identities = 119/361 (32%), Positives = 161/361 (44%), Gaps = 42/361 (11%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV R C P N CTG Y SC CP N FR EQC N
Sbjct: 167 CSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYHSCSLMPCPPNGKSFRHEQCEAKNG 226
Query: 117 VTFRGKKYR----WVP-YLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
K + WVP Y V + C+LTC G +Y KV DGT C S VC
Sbjct: 227 YQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRPYSNSVC 286
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLR-KGYNDILLIPEGA 228
V G C GCD ++GS + DKC C G+ +C K++ T + + KGY D++ IPEGA
Sbjct: 287 VRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSC---TKIVGTFNKKSKGYTDVVRIPEGA 343
Query: 229 TTIYITEIEPSNN-----YLALRSKNGTYYLNGDYHIDFPRS-MTIAGALWNYERNQQGI 282
T I + + + + YLAL+ KNG Y +NG Y I + + I G + NY
Sbjct: 344 THIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSH-- 401
Query: 283 TAPDKLRSLG--PINEPLYLSLLLIDENVGVEYEYSLPIEKAPLP--------------- 325
D L +G E L + +L D ++ YS + K P
Sbjct: 402 -RDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGS 460
Query: 326 -TQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQA 384
T + WV G + +CS TC G +R V C+ + +G C +P+ + C +
Sbjct: 461 HTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGN--RKLAKG-CPLSQRPSAFKQCLLKK 517
Query: 385 C 385
C
Sbjct: 518 C 518
Score = 40.7 bits (91), Expect = 0.055
Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 1/80 (1%)
Query: 606 VDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFS 665
V + PK +V +W PW C+++C G R+V C G ++ +
Sbjct: 439 VPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLA 498
Query: 666 -DCPKKSLPDSAGSCNEQSC 684
CP P + C + C
Sbjct: 499 KGCPLSQRPSAFKQCLLKKC 518
Score = 34.7 bits (76), Expect = 3.6
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKN 480
P W PW C + C +G TR V C N
Sbjct: 465 PQWVTGPWLACSRTCDTGWHTRTVQCQDGN 494
Score = 33.5 bits (73), Expect = 8.4
Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCE 414
PQWV G W CS+ C G +R V+C+
Sbjct: 465 PQWVTGPWLACSRTC-DTGWHTRTVQCQ 491
>BC093777-1|AAH93777.1| 930|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
Length = 930
Score = 163 bits (397), Expect = 5e-39
Identities = 119/361 (32%), Positives = 161/361 (44%), Gaps = 42/361 (11%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV R C P N CTG Y SC CP N FR EQC N
Sbjct: 579 CSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNG 638
Query: 117 VTFRGKKYR----WVP-YLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
K + WVP Y V + C+LTC G +Y KV DGT C S VC
Sbjct: 639 YQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRPYSNSVC 698
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLR-KGYNDILLIPEGA 228
V G C GCD ++GS + DKC C G+ +C K++ T + + KGY D++ IPEGA
Sbjct: 699 VRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSC---TKIVGTFNKKSKGYTDVVRIPEGA 755
Query: 229 TTIYITEIEPSNN-----YLALRSKNGTYYLNGDYHIDFPRS-MTIAGALWNYERNQQGI 282
T I + + + + YLAL+ KNG Y +NG Y I + + I G + NY
Sbjct: 756 THIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSH-- 813
Query: 283 TAPDKLRSLG--PINEPLYLSLLLIDENVGVEYEYSLPIEKAPLP--------------- 325
D L +G E L + +L D ++ YS + K P
Sbjct: 814 -RDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGS 872
Query: 326 -TQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQA 384
T + WV G + +CS TC G +R V C+ + +G C +P+ + C +
Sbjct: 873 HTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGN--RKLAKG-CPLSQRPSAFKQCLLKK 929
Query: 385 C 385
C
Sbjct: 930 C 930
Score = 40.7 bits (91), Expect = 0.055
Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 1/80 (1%)
Query: 606 VDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFS 665
V + PK +V +W PW C+++C G R+V C G ++ +
Sbjct: 851 VPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLA 910
Query: 666 -DCPKKSLPDSAGSCNEQSC 684
CP P + C + C
Sbjct: 911 KGCPLSQRPSAFKQCLLKKC 930
Score = 34.7 bits (76), Expect = 3.6
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKN 480
P W PW C + C +G TR V C N
Sbjct: 877 PQWVTGPWLACSRTCDTGWHTRTVQCQDGN 906
Score = 33.5 bits (73), Expect = 8.4
Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCE 414
PQWV G W CS+ C G +R V+C+
Sbjct: 877 PQWVTGPWLACSRTC-DTGWHTRTVQCQ 903
>BC093775-1|AAH93775.1| 930|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif, 5 (aggrecanase-2) protein.
Length = 930
Score = 163 bits (397), Expect = 5e-39
Identities = 119/361 (32%), Positives = 161/361 (44%), Gaps = 42/361 (11%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV R C P N CTG Y SC CP N FR EQC N
Sbjct: 579 CSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNG 638
Query: 117 VTFRGKKYR----WVP-YLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
K + WVP Y V + C+LTC G +Y KV DGT C S VC
Sbjct: 639 YQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRPYSNSVC 698
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLR-KGYNDILLIPEGA 228
V G C GCD ++GS + DKC C G+ +C K++ T + + KGY D++ IPEGA
Sbjct: 699 VRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSC---TKIVGTFNKKSKGYTDVVRIPEGA 755
Query: 229 TTIYITEIEPSNN-----YLALRSKNGTYYLNGDYHIDFPRS-MTIAGALWNYERNQQGI 282
T I + + + + YLAL+ KNG Y +NG Y I + + I G + NY
Sbjct: 756 THIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSH-- 813
Query: 283 TAPDKLRSLG--PINEPLYLSLLLIDENVGVEYEYSLPIEKAPLP--------------- 325
D L +G E L + +L D ++ YS + K P
Sbjct: 814 -RDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGS 872
Query: 326 -TQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQA 384
T + WV G + +CS TC G +R V C+ + +G C +P+ + C +
Sbjct: 873 HTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGN--RKLAKG-CPLSQRPSAFKQCLLKK 929
Query: 385 C 385
C
Sbjct: 930 C 930
Score = 40.7 bits (91), Expect = 0.055
Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 1/80 (1%)
Query: 606 VDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFS 665
V + PK +V +W PW C+++C G R+V C G ++ +
Sbjct: 851 VPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLA 910
Query: 666 -DCPKKSLPDSAGSCNEQSC 684
CP P + C + C
Sbjct: 911 KGCPLSQRPSAFKQCLLKKC 930
Score = 34.7 bits (76), Expect = 3.6
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKN 480
P W PW C + C +G TR V C N
Sbjct: 877 PQWVTGPWLACSRTCDTGWHTRTVQCQDGN 906
Score = 33.5 bits (73), Expect = 8.4
Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCE 414
PQWV G W CS+ C G +R V+C+
Sbjct: 877 PQWVTGPWLACSRTC-DTGWHTRTVQCQ 903
>AY172951-1|AAO45695.1| 387|Homo sapiens disintegrin and
metalloprotease-like protein protein.
Length = 387
Score = 163 bits (397), Expect = 5e-39
Identities = 121/396 (30%), Positives = 179/396 (45%), Gaps = 54/396 (13%)
Query: 292 GPINEPLYLSLLLIDENVGVEYEYSLP--IEKAPLPTQR--YSWVHGNFSSCSATCGGGI 347
GP NE L +L+ +N G+ ++Y+LP + P T+R Y+W S CS +CGGG
Sbjct: 1 GPTNETLVFEILMQGKNPGIAWKYALPKVMNGTPPATKRPAYTWSIVQ-SECSVSCGGGY 59
Query: 348 QSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSRCSKRCGKDGT 406
+ C R++ V+ C KP T + CN +CP W+PG WS CSK C G
Sbjct: 60 INVKAICL-RDQNTQVNSSFCSAKTKPVTEPKICNAFSCPAYWMPGEWSTCSKACA-GGQ 117
Query: 407 RSREVRCEKIITNGLPSVVDDKECFDLLG-PKPALYESCNVDAACPTWFISPWKPCDKLC 465
+SR+++C P ++ L P ++CN A P W + PW C K C
Sbjct: 118 QSRKIQC----VQKKPFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLGPWSQCSKTC 173
Query: 466 GSGQQTRQVVCYQKNNGRINVLSDDEC-SEEKPLDRQPCELEPC---EGVDWMVSEWTGC 521
G G + R+++C L + +C S +P ++ C L C + W+ S W+ C
Sbjct: 174 GRGVRKRELLC---KGSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRLQWVASSWSEC 230
Query: 522 D-TCLATVRSRVAQCVTKDYRVVNSSF----CS--YHPTPALEEPCDKDKLPACQVQ--- 571
TC VR R +C K ++ +F C P LEE C++ PA V
Sbjct: 231 SATCGLGVRKREMKCSEKGFQGKLITFPERRCRNIKKPNLDLEETCNRRACPAHPVYNMV 290
Query: 572 --WYATQWSKCSVECGVGKKTRRVFCGKFDGAS----------VMKVDDSN-CPKEEKYN 618
WY+ W +C+V CG G +TR V C + S V++ ++N CP EK
Sbjct: 291 AGWYSLPWQQCTVTCGGGVQTRSVHCVQQGRPSSTCLLHQKPPVLRACNTNFCPAPEKRE 350
Query: 619 DSKPCE-------VPEE-KCPSKWYAAPWSECTKSC 646
D + VP+ C K+Y +C KSC
Sbjct: 351 DPSCVDFFNWCHLVPQHGVCNHKFYG---KQCCKSC 383
Score = 134 bits (324), Expect = 3e-30
Identities = 78/257 (30%), Positives = 112/257 (43%), Gaps = 17/257 (6%)
Query: 444 CNVDAACPT-WFISPWKPCDKLCGSGQQTRQVVCYQKNN-GRINVLSDDECSEEKPLDRQ 501
CN +CP W W C K C GQQ+R++ C QK + + C P Q
Sbjct: 92 CNA-FSCPAYWMPGEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQ 150
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C C W + W+ C TC VR R C + S C+ P P L+E C
Sbjct: 151 ACNSHACPP-QWSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGC 209
Query: 561 DKDKLPA-CQVQWYATQWSKCSVECGVGKKTRRVFCGK--FDGASVMKVDDSNCPKEEKY 617
+ P ++QW A+ WS+CS CG+G + R + C + F G ++ + C +K
Sbjct: 210 VLGRCPKNSRLQWVASSWSECSATCGLGVRKREMKCSEKGFQG-KLITFPERRCRNIKKP 268
Query: 618 NDSKPCEVPEEKCPSK--------WYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPK 669
N CP+ WY+ PW +CT +CG G++ RSV C++ G+ S C
Sbjct: 269 NLDLEETCNRRACPAHPVYNMVAGWYSLPWQQCTVTCGGGVQTRSVHCVQQGRPSSTCLL 328
Query: 670 KSLPDSAGSCNEQSCEA 686
P +CN C A
Sbjct: 329 HQKPPVLRACNTNFCPA 345
>AF142099-1|AAD49577.1| 930|Homo sapiens aggrecanase-2 protein.
Length = 930
Score = 163 bits (397), Expect = 5e-39
Identities = 119/361 (32%), Positives = 161/361 (44%), Gaps = 42/361 (11%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV R C P N CTG Y SC CP N FR EQC N
Sbjct: 579 CSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNG 638
Query: 117 VTFRGKKYR----WVP-YLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
K + WVP Y V + C+LTC G +Y KV DGT C S VC
Sbjct: 639 YQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRPYSNSVC 698
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLR-KGYNDILLIPEGA 228
V G C GCD ++GS + DKC C G+ +C K++ T + + KGY D++ IPEGA
Sbjct: 699 VRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSC---TKIVGTFNKKSKGYTDVVRIPEGA 755
Query: 229 TTIYITEIEPSNN-----YLALRSKNGTYYLNGDYHIDFPRS-MTIAGALWNYERNQQGI 282
T I + + + + YLAL+ KNG Y +NG Y I + + I G + NY
Sbjct: 756 THIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSH-- 813
Query: 283 TAPDKLRSLG--PINEPLYLSLLLIDENVGVEYEYSLPIEKAPLP--------------- 325
D L +G E L + +L D ++ YS + K P
Sbjct: 814 -RDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGS 872
Query: 326 -TQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQA 384
T + WV G + +CS TC G +R V C+ + +G C +P+ + C +
Sbjct: 873 HTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGN--RKLAKG-CPLSQRPSAFKQCLLKK 929
Query: 385 C 385
C
Sbjct: 930 C 930
Score = 40.7 bits (91), Expect = 0.055
Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 1/80 (1%)
Query: 606 VDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFS 665
V + PK +V +W PW C+++C G R+V C G ++ +
Sbjct: 851 VPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLA 910
Query: 666 -DCPKKSLPDSAGSCNEQSC 684
CP P + C + C
Sbjct: 911 KGCPLSQRPSAFKQCLLKKC 930
Score = 34.7 bits (76), Expect = 3.6
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKN 480
P W PW C + C +G TR V C N
Sbjct: 877 PQWVTGPWLACSRTCDTGWHTRTVQCQDGN 906
Score = 33.5 bits (73), Expect = 8.4
Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCE 414
PQWV G W CS+ C G +R V+C+
Sbjct: 877 PQWVTGPWLACSRTC-DTGWHTRTVQCQ 903
>AP001697-2|BAA95503.1| 517|Homo sapiens disintegrin-like and
metalloprotease with thrombospondin type 1 motif, 5
protein.
Length = 517
Score = 162 bits (394), Expect = 1e-38
Identities = 119/361 (32%), Positives = 161/361 (44%), Gaps = 42/361 (11%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV R C P N CTG Y SC CP N FR EQC N
Sbjct: 166 CSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRHEQCEAKNG 225
Query: 117 VTFRGKKYR----WVP-YLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVC 169
K + WVP Y V + C+LTC G +Y KV DGT C S VC
Sbjct: 226 YQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRLYSNSVC 285
Query: 170 VDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLR-KGYNDILLIPEGA 228
V G C GCD ++GS + DKC C G+ +C K++ T + + KGY D++ IPEGA
Sbjct: 286 VRGKCVRTGCDGIIGSKLQYDKCGVCGGDNSSC---TKIVGTFNKKSKGYTDVVRIPEGA 342
Query: 229 TTIYITEIEPSNN-----YLALRSKNGTYYLNGDYHIDFPRS-MTIAGALWNYERNQQGI 282
T I + + + + YLAL+ KNG Y +NG Y I + + I G + NY
Sbjct: 343 THIKVRQFKAKDQTRFTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSH-- 400
Query: 283 TAPDKLRSLG--PINEPLYLSLLLIDENVGVEYEYSLPIEKAPLP--------------- 325
D L +G E L + +L D ++ YS + K P
Sbjct: 401 -RDDFLHGMGYSATKEILIVQILATDPTKPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGS 459
Query: 326 -TQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQA 384
T + WV G + +CS TC G +R V C+ + +G C +P+ + C +
Sbjct: 460 HTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGN--RKLAKG-CPLSQRPSAFKQCLLKK 516
Query: 385 C 385
C
Sbjct: 517 C 517
Score = 40.7 bits (91), Expect = 0.055
Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 1/80 (1%)
Query: 606 VDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFS 665
V + PK +V +W PW C+++C G R+V C G ++ +
Sbjct: 438 VPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLA 497
Query: 666 -DCPKKSLPDSAGSCNEQSC 684
CP P + C + C
Sbjct: 498 KGCPLSQRPSAFKQCLLKKC 517
Score = 34.7 bits (76), Expect = 3.6
Identities = 12/30 (40%), Positives = 14/30 (46%)
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKN 480
P W PW C + C +G TR V C N
Sbjct: 464 PQWVTGPWLACSRTCDTGWHTRTVQCQDGN 493
Score = 33.5 bits (73), Expect = 8.4
Identities = 13/28 (46%), Positives = 17/28 (60%), Gaps = 1/28 (3%)
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCE 414
PQWV G W CS+ C G +R V+C+
Sbjct: 464 PQWVTGPWLACSRTC-DTGWHTRTVQCQ 490
>AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 157 bits (380), Expect = 5e-37
Identities = 82/241 (34%), Positives = 126/241 (52%), Gaps = 14/241 (5%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPP 387
Y W + F+ CS +CGGG+Q V+C +++ E +E LC +P ++CN CP
Sbjct: 110 YDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPA 169
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVV--DDKECFDLLGPKPALYESCN 445
+W G WS CS CG G ++R+V C +++ + V D+ C PKP+ ++CN
Sbjct: 170 RWEIGKWSPCSLTCGV-GLQTRDVFCSHLLSREMNETVILADELCRQ---PKPSTVQACN 225
Query: 446 VDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQK-NNGRINVLSDDECSEEKPLDRQPCE 504
P W+ + W+PC + CG G Q R+V+C Q+ +G L + CS KP +Q C+
Sbjct: 226 RFNCPPAWYPAQWQPCSRTCGGGVQKREVLCKQRMADGSFLELPETFCSASKPACQQACK 285
Query: 505 LEPCEGVDWMVSEWTGCDT-CLATVRSRVAQC----VTKDYRVVNSSFCSYHPTPALEEP 559
+ C +W++S+WT C T C ++R A C T VVNS+ C P + P
Sbjct: 286 KDDCPS-EWLLSDWTECSTSCGEGTQTRSAICRKMLKTGLSTVVNSTLCPPLPFSSSIRP 344
Query: 560 C 560
C
Sbjct: 345 C 345
Score = 120 bits (288), Expect = 7e-26
Identities = 93/325 (28%), Positives = 140/325 (43%), Gaps = 48/325 (14%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELE--VVDEGLCD-DGLKPATNQTCNTQACP---PQW 389
+S+C+ TCG G Q R V C+ V D + + +G KPA+ + C C P++
Sbjct: 32 WSACTVTCGVGTQVRIVRCQVLLSFSQSVADLPIDECEGPKPASQRACYAGPCSGEIPEF 91
Query: 390 VPG----------------NW-----SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
P +W ++CS+ CG G + V C + ++
Sbjct: 92 NPDETDGLFGGLQDFDELYDWEYEGFTKCSESCG-GGVQEAVVSC---LNKQTREPAEEN 147
Query: 429 ECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRIN--- 485
C P P L +SCN+D W I W PC CG G QTR V C + +N
Sbjct: 148 LCVTSRRP-PQLLKSCNLDPCPARWEIGKWSPCSLTCGVGLQTRDVFCSHLLSREMNETV 206
Query: 486 VLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK----DY 540
+L+D+ C + KP Q C C W ++W C TC V+ R C + +
Sbjct: 207 ILADELCRQPKPSTVQACNRFNCPPA-WYPAQWQPCSRTCGGGVQKREVLCKQRMADGSF 265
Query: 541 RVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKF-- 598
+ +FCS PA ++ C KD P+ +W + W++CS CG G +TR C K
Sbjct: 266 LELPETFCSASK-PACQQACKKDDCPS---EWLLSDWTECSTSCGEGTQTRSAICRKMLK 321
Query: 599 DGASVMKVDDSNCPKEEKYNDSKPC 623
G S + V+ + CP + +PC
Sbjct: 322 TGLSTV-VNSTLCPPLPFSSSIRPC 345
Score = 119 bits (287), Expect = 1e-25
Identities = 81/257 (31%), Positives = 123/257 (47%), Gaps = 18/257 (7%)
Query: 314 EYSLPIEKAPLPTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGL 372
E + ++KA L Q Y W ++CSA+CG G+Q + C V+ C +
Sbjct: 975 EAGVLMQKASLVIQDYWWSVDRLATCSASCGNRGVQQPRLRCLLNST--EVNPAHCAGKV 1032
Query: 373 KPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
+PA CN + CP +W+ +WS C++ CG G ++R V C+K+ +G+ + V + C
Sbjct: 1033 RPAVQPIACNRRDCPSRWMVTSWSACTRSCG-GGVQTRRVTCQKLKASGISTPVSNDMCT 1091
Query: 432 DLLGPKPALYESCNVDAACPTWFISPWKPCDKLC---GSGQQTRQVVCYQKNNGRINVLS 488
+ +P ++CN C W S W C+ C Q RQV C Q +G L
Sbjct: 1092 Q-VAKRPVDTQACN-QQLCVEWAFSSWGQCNGPCIGPHLAVQHRQVFC-QTRDG--ITLP 1146
Query: 489 DDECSE-EKPLDRQPCELEPCEGVDWMVSEWTGCD-TC-LATVRSRVAQCV-TKDYRVVN 544
++CS +P+ Q C E C V W VS WT C TC +SR +CV + + V
Sbjct: 1147 SEQCSALPRPVSTQNCWSEAC-SVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVP 1205
Query: 545 SSFCSYHPTPALEEPCD 561
CS+ P PA + C+
Sbjct: 1206 EHLCSWGPRPANWQRCN 1222
Score = 106 bits (255), Expect = 7e-22
Identities = 80/301 (26%), Positives = 126/301 (41%), Gaps = 41/301 (13%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC--- 444
+++P WS C+ CG GT+ R VRC+ +++ V D + GPKPA +C
Sbjct: 26 RFIPEAWSACTVTCGV-GTQVRIVRCQVLLS--FSQSVADLPIDECEGPKPASQRACYAG 82
Query: 445 ---------NVDAA------------CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGR 483
N D W + C + CG G Q V C K
Sbjct: 83 PCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTRE 142
Query: 484 INVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRV 542
+ S P + C L+PC W + +W+ C TC +++R C R
Sbjct: 143 PAEENLCVTSRRPPQLLKSCNLDPCPA-RWEIGKWSPCSLTCGVGLQTRDVFCSHLLSRE 201
Query: 543 VNSSFC-----SYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCG- 596
+N + P P+ + C++ P WY QW CS CG G + R V C
Sbjct: 202 MNETVILADELCRQPKPSTVQACNRFNCPPA---WYPAQWQPCSRTCGGGVQKREVLCKQ 258
Query: 597 KFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVV 656
+ S +++ ++ C K + C+ ++ CPS+W + W+EC+ SCG+G + RS +
Sbjct: 259 RMADGSFLELPETFC-SASKPACQQACK--KDDCPSEWLLSDWTECSTSCGEGTQTRSAI 315
Query: 657 C 657
C
Sbjct: 316 C 316
Score = 105 bits (251), Expect = 2e-21
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 23/217 (10%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYE-SCNVD 447
W + CS CG G + +RC + N + V+ C + +PA+ +CN
Sbjct: 992 WSVDRLATCSASCGNRGVQQPRLRC---LLNS--TEVNPAHCAGKV--RPAVQPIACN-R 1043
Query: 448 AACPT-WFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSE--EKPLDRQPC 503
CP+ W ++ W C + CG G QTR+V C + K +G +S+D C++ ++P+D Q C
Sbjct: 1044 RDCPSRWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQAC 1103
Query: 504 ELEPCEGVDWMVSEWTGCD-TCLA---TVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP 559
+ C V+W S W C+ C+ V+ R C T+D + S CS P P +
Sbjct: 1104 NQQLC--VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVSTQN 1161
Query: 560 CDKDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFC 595
C + AC V W + W+ C+ CG G ++RRV C
Sbjct: 1162 CWSE---ACSVHWRVSLWTLCTATCGNYGFQSRRVEC 1195
Score = 89.4 bits (212), Expect = 1e-16
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 17/187 (9%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEV---VDEGLCDDGLK-PATNQTCNTQACP 386
W+ ++S+C+ +CGGG+Q+R VTC+ + + V +C K P Q CN Q C
Sbjct: 1050 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQLC- 1108
Query: 387 PQWVPGNWSRCSKRC-GKD-GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC 444
+W +W +C+ C G + R+V C+ LPS ++C L P+P ++C
Sbjct: 1109 VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPS----EQCSAL--PRPVSTQNC 1162
Query: 445 NVDAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQP 502
+A W +S W C CG+ G Q+R+V C + + + CS +P + Q
Sbjct: 1163 WSEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNK--AVPEHLCSWGPRPANWQR 1220
Query: 503 CELEPCE 509
C + PCE
Sbjct: 1221 CNITPCE 1227
Score = 60.5 bits (140), Expect = 6e-08
Identities = 61/247 (24%), Positives = 98/247 (39%), Gaps = 25/247 (10%)
Query: 453 WFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQP--CELEPCE 509
W + C CG+ G Q ++ C N+ +N C+ + QP C C
Sbjct: 992 WSVDRLATCSASCGNRGVQQPRLRCLL-NSTEVNPA---HCAGKVRPAVQPIACNRRDCP 1047
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL--P 566
WMV+ W+ C +C V++R C +++ + T + P D
Sbjct: 1048 S-RWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQ 1106
Query: 567 ACQVQWYATQWSKCSVEC---GVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C V+W + W +C+ C + + R+VFC DG ++ S P+ ++ C
Sbjct: 1107 LC-VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVS---TQNC 1162
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGK-GLRFRSVVCL--RGGKEFSD--CPKKSLPDSAGS 678
E C W + W+ CT +CG G + R V C+ R K + C P +
Sbjct: 1163 W--SEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQR 1220
Query: 679 CNEQSCE 685
CN CE
Sbjct: 1221 CNITPCE 1227
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 331 WVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
W ++ C+ATCG G QSR V C + V E LC G +PA Q CN C
Sbjct: 1171 WRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNITPCENSM 1230
Query: 390 VPGNWSRCSK 399
C K
Sbjct: 1231 CRDTTRYCEK 1240
Score = 34.3 bits (75), Expect = 4.8
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
Query: 57 PCSRTCGGGVASQKRICLEIGPNG------EPQCTGGDTK-YFSCETQDCPENSL 104
PCSRTCGGGV ++ +C + +G E C+ +C+ DCP L
Sbjct: 240 PCSRTCGGGVQKREVLCKQRMADGSFLELPETFCSASKPACQQACKKDDCPSEWL 294
>AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 157 bits (380), Expect = 5e-37
Identities = 82/241 (34%), Positives = 126/241 (52%), Gaps = 14/241 (5%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPP 387
Y W + F+ CS +CGGG+Q V+C +++ E +E LC +P ++CN CP
Sbjct: 110 YDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPA 169
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVV--DDKECFDLLGPKPALYESCN 445
+W G WS CS CG G ++R+V C +++ + V D+ C PKP+ ++CN
Sbjct: 170 RWEIGKWSPCSLTCGV-GLQTRDVFCSHLLSREMNETVILADELCRQ---PKPSTVQACN 225
Query: 446 VDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQK-NNGRINVLSDDECSEEKPLDRQPCE 504
P W+ + W+PC + CG G Q R+V+C Q+ +G L + CS KP +Q C+
Sbjct: 226 RFNCPPAWYPAQWQPCSRTCGGGVQKREVLCKQRMADGSFLELPETFCSASKPACQQACK 285
Query: 505 LEPCEGVDWMVSEWTGCDT-CLATVRSRVAQC----VTKDYRVVNSSFCSYHPTPALEEP 559
+ C +W++S+WT C T C ++R A C T VVNS+ C P + P
Sbjct: 286 KDDCPS-EWLLSDWTECSTSCGEGTQTRSAICRKMLKTGLSTVVNSTLCPPLPFSSSIRP 344
Query: 560 C 560
C
Sbjct: 345 C 345
Score = 120 bits (288), Expect = 7e-26
Identities = 93/325 (28%), Positives = 140/325 (43%), Gaps = 48/325 (14%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELE--VVDEGLCD-DGLKPATNQTCNTQACP---PQW 389
+S+C+ TCG G Q R V C+ V D + + +G KPA+ + C C P++
Sbjct: 32 WSACTVTCGVGTQVRIVRCQVLLSFSQSVADLPIDECEGPKPASQRACYAGPCSGEIPEF 91
Query: 390 VPG----------------NW-----SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
P +W ++CS+ CG G + V C + ++
Sbjct: 92 NPDETDGLFGGLQDFDELYDWEYEGFTKCSESCG-GGVQEAVVSC---LNKQTREPAEEN 147
Query: 429 ECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRIN--- 485
C P P L +SCN+D W I W PC CG G QTR V C + +N
Sbjct: 148 LCVTSRRP-PQLLKSCNLDPCPARWEIGKWSPCSLTCGVGLQTRDVFCSHLLSREMNETV 206
Query: 486 VLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK----DY 540
+L+D+ C + KP Q C C W ++W C TC V+ R C + +
Sbjct: 207 ILADELCRQPKPSTVQACNRFNCPPA-WYPAQWQPCSRTCGGGVQKREVLCKQRMADGSF 265
Query: 541 RVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKF-- 598
+ +FCS PA ++ C KD P+ +W + W++CS CG G +TR C K
Sbjct: 266 LELPETFCSASK-PACQQACKKDDCPS---EWLLSDWTECSTSCGEGTQTRSAICRKMLK 321
Query: 599 DGASVMKVDDSNCPKEEKYNDSKPC 623
G S + V+ + CP + +PC
Sbjct: 322 TGLSTV-VNSTLCPPLPFSSSIRPC 345
Score = 119 bits (287), Expect = 1e-25
Identities = 81/257 (31%), Positives = 123/257 (47%), Gaps = 18/257 (7%)
Query: 314 EYSLPIEKAPLPTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGL 372
E + ++KA L Q Y W ++CSA+CG G+Q + C V+ C +
Sbjct: 975 EAGVLMQKASLVIQDYWWSVDRLATCSASCGNRGVQQPRLRCLLNST--EVNPAHCAGKV 1032
Query: 373 KPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
+PA CN + CP +W+ +WS C++ CG G ++R V C+K+ +G+ + V + C
Sbjct: 1033 RPAVQPIACNRRDCPSRWMVTSWSACTRSCG-GGVQTRRVTCQKLKASGISTPVSNDMCT 1091
Query: 432 DLLGPKPALYESCNVDAACPTWFISPWKPCDKLC---GSGQQTRQVVCYQKNNGRINVLS 488
+ +P ++CN C W S W C+ C Q RQV C Q +G L
Sbjct: 1092 Q-VAKRPVDTQACN-QQLCVEWAFSSWGQCNGPCIGPHLAVQHRQVFC-QTRDG--ITLP 1146
Query: 489 DDECSE-EKPLDRQPCELEPCEGVDWMVSEWTGCD-TC-LATVRSRVAQCV-TKDYRVVN 544
++CS +P+ Q C E C V W VS WT C TC +SR +CV + + V
Sbjct: 1147 SEQCSALPRPVSTQNCWSEAC-SVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVP 1205
Query: 545 SSFCSYHPTPALEEPCD 561
CS+ P PA + C+
Sbjct: 1206 EHLCSWGPRPANWQRCN 1222
Score = 106 bits (255), Expect = 7e-22
Identities = 80/301 (26%), Positives = 126/301 (41%), Gaps = 41/301 (13%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC--- 444
+++P WS C+ CG GT+ R VRC+ +++ V D + GPKPA +C
Sbjct: 26 RFIPEAWSACTVTCGV-GTQVRIVRCQVLLS--FSQSVADLPIDECEGPKPASQRACYAG 82
Query: 445 ---------NVDAA------------CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGR 483
N D W + C + CG G Q V C K
Sbjct: 83 PCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTRE 142
Query: 484 INVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRV 542
+ S P + C L+PC W + +W+ C TC +++R C R
Sbjct: 143 PAEENLCVTSRRPPQLLKSCNLDPCPA-RWEIGKWSPCSLTCGVGLQTRDVFCSHLLSRE 201
Query: 543 VNSSFC-----SYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCG- 596
+N + P P+ + C++ P WY QW CS CG G + R V C
Sbjct: 202 MNETVILADELCRQPKPSTVQACNRFNCPPA---WYPAQWQPCSRTCGGGVQKREVLCKQ 258
Query: 597 KFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVV 656
+ S +++ ++ C K + C+ ++ CPS+W + W+EC+ SCG+G + RS +
Sbjct: 259 RMADGSFLELPETFC-SASKPACQQACK--KDDCPSEWLLSDWTECSTSCGEGTQTRSAI 315
Query: 657 C 657
C
Sbjct: 316 C 316
Score = 105 bits (251), Expect = 2e-21
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 23/217 (10%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYE-SCNVD 447
W + CS CG G + +RC + N + V+ C + +PA+ +CN
Sbjct: 992 WSVDRLATCSASCGNRGVQQPRLRC---LLNS--TEVNPAHCAGKV--RPAVQPIACN-R 1043
Query: 448 AACPT-WFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSE--EKPLDRQPC 503
CP+ W ++ W C + CG G QTR+V C + K +G +S+D C++ ++P+D Q C
Sbjct: 1044 RDCPSRWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQAC 1103
Query: 504 ELEPCEGVDWMVSEWTGCD-TCLA---TVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP 559
+ C V+W S W C+ C+ V+ R C T+D + S CS P P +
Sbjct: 1104 NQQLC--VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVSTQN 1161
Query: 560 CDKDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFC 595
C + AC V W + W+ C+ CG G ++RRV C
Sbjct: 1162 CWSE---ACSVHWRVSLWTLCTATCGNYGFQSRRVEC 1195
Score = 89.4 bits (212), Expect = 1e-16
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 17/187 (9%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEV---VDEGLCDDGLK-PATNQTCNTQACP 386
W+ ++S+C+ +CGGG+Q+R VTC+ + + V +C K P Q CN Q C
Sbjct: 1050 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQLC- 1108
Query: 387 PQWVPGNWSRCSKRC-GKD-GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC 444
+W +W +C+ C G + R+V C+ LPS ++C L P+P ++C
Sbjct: 1109 VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPS----EQCSAL--PRPVSTQNC 1162
Query: 445 NVDAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQP 502
+A W +S W C CG+ G Q+R+V C + + + CS +P + Q
Sbjct: 1163 WSEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNK--AVPEHLCSWGPRPANWQR 1220
Query: 503 CELEPCE 509
C + PCE
Sbjct: 1221 CNITPCE 1227
Score = 60.5 bits (140), Expect = 6e-08
Identities = 61/247 (24%), Positives = 98/247 (39%), Gaps = 25/247 (10%)
Query: 453 WFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQP--CELEPCE 509
W + C CG+ G Q ++ C N+ +N C+ + QP C C
Sbjct: 992 WSVDRLATCSASCGNRGVQQPRLRCLL-NSTEVNPA---HCAGKVRPAVQPIACNRRDCP 1047
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL--P 566
WMV+ W+ C +C V++R C +++ + T + P D
Sbjct: 1048 S-RWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQ 1106
Query: 567 ACQVQWYATQWSKCSVEC---GVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C V+W + W +C+ C + + R+VFC DG ++ S P+ ++ C
Sbjct: 1107 LC-VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVS---TQNC 1162
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGK-GLRFRSVVCL--RGGKEFSD--CPKKSLPDSAGS 678
E C W + W+ CT +CG G + R V C+ R K + C P +
Sbjct: 1163 W--SEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQR 1220
Query: 679 CNEQSCE 685
CN CE
Sbjct: 1221 CNITPCE 1227
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 331 WVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
W ++ C+ATCG G QSR V C + V E LC G +PA Q CN C
Sbjct: 1171 WRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNITPCENSM 1230
Query: 390 VPGNWSRCSK 399
C K
Sbjct: 1231 CRDTTRYCEK 1240
Score = 34.3 bits (75), Expect = 4.8
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
Query: 57 PCSRTCGGGVASQKRICLEIGPNG------EPQCTGGDTK-YFSCETQDCPENSL 104
PCSRTCGGGV ++ +C + +G E C+ +C+ DCP L
Sbjct: 240 PCSRTCGGGVQKREVLCKQRMADGSFLELPETFCSASKPACQQACKKDDCPSEWL 294
>AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open reading
frame 9 protein.
Length = 1263
Score = 157 bits (380), Expect = 5e-37
Identities = 82/241 (34%), Positives = 126/241 (52%), Gaps = 14/241 (5%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPP 387
Y W + F+ CS +CGGG+Q V+C +++ E +E LC +P ++CN CP
Sbjct: 110 YDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPA 169
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVV--DDKECFDLLGPKPALYESCN 445
+W G WS CS CG G ++R+V C +++ + V D+ C PKP+ ++CN
Sbjct: 170 RWEIGKWSPCSLTCGV-GLQTRDVFCSHLLSREMNETVILADELCRQ---PKPSTVQACN 225
Query: 446 VDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQK-NNGRINVLSDDECSEEKPLDRQPCE 504
P W+ + W+PC + CG G Q R+V+C Q+ +G L + CS KP +Q C+
Sbjct: 226 RFNCPPAWYPAQWQPCSRTCGGGVQKREVLCKQRMADGSFLELPETFCSASKPACQQACK 285
Query: 505 LEPCEGVDWMVSEWTGCDT-CLATVRSRVAQC----VTKDYRVVNSSFCSYHPTPALEEP 559
+ C +W++S+WT C T C ++R A C T VVNS+ C P + P
Sbjct: 286 KDDCPS-EWLLSDWTECSTSCGEGTQTRSAICRKMLKTGLSTVVNSTLCPPLPFSSSIRP 344
Query: 560 C 560
C
Sbjct: 345 C 345
Score = 120 bits (288), Expect = 7e-26
Identities = 93/325 (28%), Positives = 140/325 (43%), Gaps = 48/325 (14%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELE--VVDEGLCD-DGLKPATNQTCNTQACP---PQW 389
+S+C+ TCG G Q R V C+ V D + + +G KPA+ + C C P++
Sbjct: 32 WSACTVTCGVGTQVRIVRCQVLLSFSQSVADLPIDECEGPKPASQRACYAGPCSGEIPEF 91
Query: 390 VPG----------------NW-----SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
P +W ++CS+ CG G + V C + ++
Sbjct: 92 NPDETDGLFGGLQDFDELYDWEYEGFTKCSESCG-GGVQEAVVSC---LNKQTREPAEEN 147
Query: 429 ECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRIN--- 485
C P P L +SCN+D W I W PC CG G QTR V C + +N
Sbjct: 148 LCVTSRRP-PQLLKSCNLDPCPARWEIGKWSPCSLTCGVGLQTRDVFCSHLLSREMNETV 206
Query: 486 VLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTK----DY 540
+L+D+ C + KP Q C C W ++W C TC V+ R C + +
Sbjct: 207 ILADELCRQPKPSTVQACNRFNCPPA-WYPAQWQPCSRTCGGGVQKREVLCKQRMADGSF 265
Query: 541 RVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKF-- 598
+ +FCS PA ++ C KD P+ +W + W++CS CG G +TR C K
Sbjct: 266 LELPETFCSASK-PACQQACKKDDCPS---EWLLSDWTECSTSCGEGTQTRSAICRKMLK 321
Query: 599 DGASVMKVDDSNCPKEEKYNDSKPC 623
G S + V+ + CP + +PC
Sbjct: 322 TGLSTV-VNSTLCPPLPFSSSIRPC 345
Score = 119 bits (287), Expect = 1e-25
Identities = 81/257 (31%), Positives = 123/257 (47%), Gaps = 18/257 (7%)
Query: 314 EYSLPIEKAPLPTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGL 372
E + ++KA L Q Y W ++CSA+CG G+Q + C V+ C +
Sbjct: 975 EAGVLMQKASLVIQDYWWSVDRLATCSASCGNRGVQQPRLRCLLNST--EVNPAHCAGKV 1032
Query: 373 KPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
+PA CN + CP +W+ +WS C++ CG G ++R V C+K+ +G+ + V + C
Sbjct: 1033 RPAVQPIACNRRDCPSRWMVTSWSACTRSCG-GGVQTRRVTCQKLKASGISTPVSNDMCT 1091
Query: 432 DLLGPKPALYESCNVDAACPTWFISPWKPCDKLC---GSGQQTRQVVCYQKNNGRINVLS 488
+ +P ++CN C W S W C+ C Q RQV C Q +G L
Sbjct: 1092 Q-VAKRPVDTQACN-QQLCVEWAFSSWGQCNGPCIGPHLAVQHRQVFC-QTRDG--ITLP 1146
Query: 489 DDECSE-EKPLDRQPCELEPCEGVDWMVSEWTGCD-TC-LATVRSRVAQCV-TKDYRVVN 544
++CS +P+ Q C E C V W VS WT C TC +SR +CV + + V
Sbjct: 1147 SEQCSALPRPVSTQNCWSEAC-SVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVP 1205
Query: 545 SSFCSYHPTPALEEPCD 561
CS+ P PA + C+
Sbjct: 1206 EHLCSWGPRPANWQRCN 1222
Score = 106 bits (255), Expect = 7e-22
Identities = 80/301 (26%), Positives = 126/301 (41%), Gaps = 41/301 (13%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC--- 444
+++P WS C+ CG GT+ R VRC+ +++ V D + GPKPA +C
Sbjct: 26 RFIPEAWSACTVTCGV-GTQVRIVRCQVLLS--FSQSVADLPIDECEGPKPASQRACYAG 82
Query: 445 ---------NVDAA------------CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGR 483
N D W + C + CG G Q V C K
Sbjct: 83 PCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEAVVSCLNKQTRE 142
Query: 484 INVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRV 542
+ S P + C L+PC W + +W+ C TC +++R C R
Sbjct: 143 PAEENLCVTSRRPPQLLKSCNLDPCPA-RWEIGKWSPCSLTCGVGLQTRDVFCSHLLSRE 201
Query: 543 VNSSFC-----SYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCG- 596
+N + P P+ + C++ P WY QW CS CG G + R V C
Sbjct: 202 MNETVILADELCRQPKPSTVQACNRFNCPPA---WYPAQWQPCSRTCGGGVQKREVLCKQ 258
Query: 597 KFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVV 656
+ S +++ ++ C K + C+ ++ CPS+W + W+EC+ SCG+G + RS +
Sbjct: 259 RMADGSFLELPETFC-SASKPACQQACK--KDDCPSEWLLSDWTECSTSCGEGTQTRSAI 315
Query: 657 C 657
C
Sbjct: 316 C 316
Score = 105 bits (251), Expect = 2e-21
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 23/217 (10%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYE-SCNVD 447
W + CS CG G + +RC + N + V+ C + +PA+ +CN
Sbjct: 992 WSVDRLATCSASCGNRGVQQPRLRC---LLNS--TEVNPAHCAGKV--RPAVQPIACN-R 1043
Query: 448 AACPT-WFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSE--EKPLDRQPC 503
CP+ W ++ W C + CG G QTR+V C + K +G +S+D C++ ++P+D Q C
Sbjct: 1044 RDCPSRWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQAC 1103
Query: 504 ELEPCEGVDWMVSEWTGCD-TCLA---TVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP 559
+ C V+W S W C+ C+ V+ R C T+D + S CS P P +
Sbjct: 1104 NQQLC--VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVSTQN 1161
Query: 560 CDKDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFC 595
C + AC V W + W+ C+ CG G ++RRV C
Sbjct: 1162 CWSE---ACSVHWRVSLWTLCTATCGNYGFQSRRVEC 1195
Score = 89.4 bits (212), Expect = 1e-16
Identities = 57/187 (30%), Positives = 92/187 (49%), Gaps = 17/187 (9%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEV---VDEGLCDDGLK-PATNQTCNTQACP 386
W+ ++S+C+ +CGGG+Q+R VTC+ + + V +C K P Q CN Q C
Sbjct: 1050 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQLC- 1108
Query: 387 PQWVPGNWSRCSKRC-GKD-GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC 444
+W +W +C+ C G + R+V C+ LPS ++C L P+P ++C
Sbjct: 1109 VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPS----EQCSAL--PRPVSTQNC 1162
Query: 445 NVDAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQP 502
+A W +S W C CG+ G Q+R+V C + + + CS +P + Q
Sbjct: 1163 WSEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNK--AVPEHLCSWGPRPANWQR 1220
Query: 503 CELEPCE 509
C + PCE
Sbjct: 1221 CNITPCE 1227
Score = 60.5 bits (140), Expect = 6e-08
Identities = 61/247 (24%), Positives = 98/247 (39%), Gaps = 25/247 (10%)
Query: 453 WFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQP--CELEPCE 509
W + C CG+ G Q ++ C N+ +N C+ + QP C C
Sbjct: 992 WSVDRLATCSASCGNRGVQQPRLRCLL-NSTEVNPA---HCAGKVRPAVQPIACNRRDCP 1047
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL--P 566
WMV+ W+ C +C V++R C +++ + T + P D
Sbjct: 1048 S-RWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQ 1106
Query: 567 ACQVQWYATQWSKCSVEC---GVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C V+W + W +C+ C + + R+VFC DG ++ S P+ ++ C
Sbjct: 1107 LC-VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVS---TQNC 1162
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGK-GLRFRSVVCL--RGGKEFSD--CPKKSLPDSAGS 678
E C W + W+ CT +CG G + R V C+ R K + C P +
Sbjct: 1163 W--SEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQR 1220
Query: 679 CNEQSCE 685
CN CE
Sbjct: 1221 CNITPCE 1227
Score = 44.4 bits (100), Expect = 0.004
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Query: 331 WVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
W ++ C+ATCG G QSR V C + V E LC G +PA Q CN C
Sbjct: 1171 WRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNITPCENSM 1230
Query: 390 VPGNWSRCSK 399
C K
Sbjct: 1231 CRDTTRYCEK 1240
Score = 34.3 bits (75), Expect = 4.8
Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 7/55 (12%)
Query: 57 PCSRTCGGGVASQKRICLEIGPNG------EPQCTGGDTK-YFSCETQDCPENSL 104
PCSRTCGGGV ++ +C + +G E C+ +C+ DCP L
Sbjct: 240 PCSRTCGGGVQKREVLCKQRMADGSFLELPETFCSASKPACQQACKKDDCPSEWL 294
>AK122677-1|BAC85503.1| 375|Homo sapiens protein ( Homo sapiens
cDNA FLJ16125 fis, clone BRACE2027018. ).
Length = 375
Score = 151 bits (367), Expect = 2e-35
Identities = 115/381 (30%), Positives = 172/381 (45%), Gaps = 54/381 (14%)
Query: 307 ENVGVEYEYSLP--IEKAPLPTQR--YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEV 362
+N G+ ++Y+LP + P T+R Y+W S CS +CGGG + C R++
Sbjct: 4 KNPGIAWKYALPKVMNGTPPATKRPAYTWSIVQ-SECSVSCGGGYINVKAICL-RDQNTQ 61
Query: 363 VDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGL 421
V+ C KP T + CN +CP W+PG WS CSK C G +SR+++C
Sbjct: 62 VNSSFCSAKTKPVTEPKICNAFSCPAYWMPGEWSTCSKACA-GGQQSRKIQC----VQKK 116
Query: 422 PSVVDDKECFDLLG-PKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKN 480
P ++ L P ++CN A P W + PW C K CG G + R+++C
Sbjct: 117 PFQKEEAVLHSLCPVSTPTQVQACNSHACPPQWSLGPWSQCSKTCGRGVRKRELLC---K 173
Query: 481 NGRINVLSDDEC-SEEKPLDRQPCELEPC---EGVDWMVSEWTGCD-TCLATVRSRVAQC 535
L + +C S +P ++ C L C + W+ S W+ C TC VR R +C
Sbjct: 174 GSAAETLPESQCTSLPRPELQEGCVLGRCPKNSRLQWVASSWSECSATCGLGVRKREMKC 233
Query: 536 VTKDYRVVNSSF----CS--YHPTPALEEPCDKDKLPACQVQ-----WYATQWSKCSVEC 584
K ++ +F C P LEE C++ PA V WY+ W +C+V C
Sbjct: 234 REKGFQGKLITFPERRCRNIKKPNLDLEETCNRRACPAHPVYNMVAGWYSLPWQQCTVTC 293
Query: 585 GVGKKTRRVFC---GKFDGA-------SVMKVDDSN-CPKEEKYNDSKPCE-------VP 626
G G +TR V C G+ + V++ ++N CP EK D + VP
Sbjct: 294 GGGVQTRSVHCVQQGRPSSSCLLHQKPPVLRACNTNFCPAPEKREDPSCVDFFNWCHLVP 353
Query: 627 EE-KCPSKWYAAPWSECTKSC 646
+ C K+Y +C KSC
Sbjct: 354 QHGVCNHKFYG---KQCCKSC 371
Score = 134 bits (323), Expect = 4e-30
Identities = 78/257 (30%), Positives = 112/257 (43%), Gaps = 17/257 (6%)
Query: 444 CNVDAACPT-WFISPWKPCDKLCGSGQQTRQVVCYQKNN-GRINVLSDDECSEEKPLDRQ 501
CN +CP W W C K C GQQ+R++ C QK + + C P Q
Sbjct: 80 CNA-FSCPAYWMPGEWSTCSKACAGGQQSRKIQCVQKKPFQKEEAVLHSLCPVSTPTQVQ 138
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C C W + W+ C TC VR R C + S C+ P P L+E C
Sbjct: 139 ACNSHACPP-QWSLGPWSQCSKTCGRGVRKRELLCKGSAAETLPESQCTSLPRPELQEGC 197
Query: 561 DKDKLPA-CQVQWYATQWSKCSVECGVGKKTRRVFCGK--FDGASVMKVDDSNCPKEEKY 617
+ P ++QW A+ WS+CS CG+G + R + C + F G ++ + C +K
Sbjct: 198 VLGRCPKNSRLQWVASSWSECSATCGLGVRKREMKCREKGFQG-KLITFPERRCRNIKKP 256
Query: 618 NDSKPCEVPEEKCPSK--------WYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPK 669
N CP+ WY+ PW +CT +CG G++ RSV C++ G+ S C
Sbjct: 257 NLDLEETCNRRACPAHPVYNMVAGWYSLPWQQCTVTCGGGVQTRSVHCVQQGRPSSSCLL 316
Query: 670 KSLPDSAGSCNEQSCEA 686
P +CN C A
Sbjct: 317 HQKPPVLRACNTNFCPA 333
>DQ217943-1|ABB70740.1| 1095|Homo sapiens ADAM metallopeptidase with
thrombospondin type 1 motif 17 protein.
Length = 1095
Score = 139 bits (336), Expect = 1e-31
Identities = 91/303 (30%), Positives = 137/303 (45%), Gaps = 30/303 (9%)
Query: 249 NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLI-DE 307
+G +N D+ I+ P IAG Y R +G+ +K+ + GP PL+L +LL D+
Sbjct: 717 SGKGSINSDWKIELPGEFQIAGTTVRYVR--RGLW--EKISAKGPTKLPLHLMVLLFHDQ 772
Query: 308 NVGVEYEYSLPIEKA------PLPTQR--YSWVHGNFSSCSATCGGGIQSRDVTCRS--R 357
+ G+ YEY++P+ + P Q + W H + CS CGGG + V+C
Sbjct: 773 DYGIHYEYTVPVNRTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTRIVN 832
Query: 358 EELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKI 416
+ +V++ C +P + CN C +WV G WS CS C K G + REV C
Sbjct: 833 KTTTLVNDSDCPQASRPEPQVRRCNLHPCQSRWVAGPWSPCSATCEK-GFQHREVTCVYQ 891
Query: 417 ITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVC 476
+ NG C GP+PA +SC W S W C CG G R V C
Sbjct: 892 LQNGTHVATRPLYC---PGPRPAAVQSCEGQDCLSIWEASEWSQCSASCGKGVWKRTVAC 948
Query: 477 YQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGC-DTCLATVRSRVAQC 535
+ G+ + + +P + CE + +W +W+ C TC ++SRV QC
Sbjct: 949 -TNSQGKCD-------ASTRPRAEEACE-DYSGCYEWKTGDWSTCSSTCGKGLQSRVVQC 999
Query: 536 VTK 538
+ K
Sbjct: 1000 MHK 1002
Score = 115 bits (277), Expect = 2e-24
Identities = 57/150 (38%), Positives = 77/150 (51%), Gaps = 2/150 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG G +R C P G C G ++ CE CP+ FR +QC ++
Sbjct: 555 CSRTCGTGARFTQRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDR 614
Query: 117 VTFRGKKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQP 176
++ + KK + KPCEL C G ++V+DGT C D+CV G CQ
Sbjct: 615 LSPK-KKGLLTAVVVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYETDLCVHGKCQK 673
Query: 177 VGCDMMLGSNAKEDKCRQCRGNGHNCHTTK 206
+GCD ++GS AKED+C C G+G CH K
Sbjct: 674 IGCDGIIGSAAKEDRCGVCSGDGKTCHLVK 703
Score = 109 bits (262), Expect = 1e-22
Identities = 72/228 (31%), Positives = 95/228 (41%), Gaps = 22/228 (9%)
Query: 377 NQTCNTQACP--PQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKE 429
N+T Q+ P PQ W W CS +CG G R V C +I+ N ++V+D +
Sbjct: 785 NRTAENQSEPEKPQDSLFIWTHSGWEGCSVQCG-GGERRTIVSCTRIV-NKTTTLVNDSD 842
Query: 430 CFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVC-YQKNNGRINVLS 488
C P+P + CN+ W PW PC C G Q R+V C YQ NG
Sbjct: 843 CPQASRPEPQV-RRCNLHPCQSRWVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATR 901
Query: 489 DDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSF 547
C +P Q CE + C + W SEW+ C +C V R C +
Sbjct: 902 PLYCPGPRPAAVQSCEGQDCLSI-WEASEWSQCSASCGKGVWKRTVACTNSQGK------ 954
Query: 548 CSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
C P EE C + C +W WS CS CG G ++R V C
Sbjct: 955 CDASTRPRAEEAC--EDYSGC-YEWKTGDWSTCSSTCGKGLQSRVVQC 999
Score = 109 bits (262), Expect = 1e-22
Identities = 74/243 (30%), Positives = 106/243 (43%), Gaps = 29/243 (11%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC---SEEKPLDRQPCELEPCE 509
W S W+ C CG G++ V C + N +++D +C S +P R+ C L PC+
Sbjct: 804 WTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRR-CNLHPCQ 862
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDK 564
W+ W+ C TC + R CV + + +C P PA + C+
Sbjct: 863 S-RWVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCP-GPRPAAVQSCEGQD 920
Query: 565 LPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK-EEKYNDSKPC 623
C W A++WS+CS CG G R V C G K D S P+ EE D C
Sbjct: 921 ---CLSIWEASEWSQCSASCGKGVWKRTVACTNSQG----KCDASTRPRAEEACEDYSGC 973
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR--GGKEFSDCPKKSLPDSAGSCNE 681
+W WS C+ +CGKGL+ R V C+ G+ S+CP S P C +
Sbjct: 974 Y--------EWKTGDWSTCSSTCGKGLQSRVVQCMHKVTGRHGSECPALSKPAPYRQCYQ 1025
Query: 682 QSC 684
+ C
Sbjct: 1026 EVC 1028
Score = 94.7 bits (225), Expect = 3e-18
Identities = 63/181 (34%), Positives = 77/181 (42%), Gaps = 20/181 (11%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTC--RSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
WV G +S CSATC G Q R+VTC + + V L G +PA Q+C Q C
Sbjct: 865 WVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCPGPRPAAVQSCEGQDCLSI 924
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W WS+CS CGK G R V C TN +C +P E+C +
Sbjct: 925 WEASEWSQCSASCGK-GVWKRTVAC----TNS------QGKCD--ASTRPRAEEACEDYS 971
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC-SEEKPLDRQPCELEP 507
C W W C CG G Q+R V C K GR EC + KP + C E
Sbjct: 972 GCYEWKTGDWSTCSSTCGKGLQSRVVQCMHKVTGR----HGSECPALSKPAPYRQCYQEV 1027
Query: 508 C 508
C
Sbjct: 1028 C 1028
Score = 76.2 bits (179), Expect = 1e-12
Identities = 41/128 (32%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDS-KPCEVPEEKC 630
W + W CSV+CG G++ V C + + V+DS+CP+ + + C + C
Sbjct: 804 WTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNL--HPC 861
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVC---LRGGKEFSD----CPKKSLPDSAGSCNEQS 683
S+W A PWS C+ +C KG + R V C L+ G + CP P + SC Q
Sbjct: 862 QSRWVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCPGPR-PAAVQSCEGQD 920
Query: 684 CEALGEGS 691
C ++ E S
Sbjct: 921 CLSIWEAS 928
Score = 44.0 bits (99), Expect = 0.006
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQAC 385
Y W G++S+CS+TCG G+QSR V C + E C KPA + C + C
Sbjct: 974 YEWKTGDWSTCSSTCGKGLQSRVVQCMHKVTGRHGSE--CPALSKPAPYRQCYQEVC 1028
>AJ315735-1|CAC86016.1| 1095|Homo sapiens metalloprotease disintegrin
17, with thrombospondin domains protein.
Length = 1095
Score = 139 bits (336), Expect = 1e-31
Identities = 91/303 (30%), Positives = 137/303 (45%), Gaps = 30/303 (9%)
Query: 249 NGTYYLNGDYHIDFPRSMTIAGALWNYERNQQGITAPDKLRSLGPINEPLYLSLLLI-DE 307
+G +N D+ I+ P IAG Y R +G+ +K+ + GP PL+L +LL D+
Sbjct: 717 SGKGSINSDWKIELPGEFQIAGTTVRYVR--RGLW--EKISAKGPTKLPLHLMVLLFHDQ 772
Query: 308 NVGVEYEYSLPIEKA------PLPTQR--YSWVHGNFSSCSATCGGGIQSRDVTCRS--R 357
+ G+ YEY++P+ + P Q + W H + CS CGGG + V+C
Sbjct: 773 DYGIHYEYTVPVNRTAENQSEPEKPQDSLFIWTHSGWEGCSVQCGGGERRTIVSCTRIVN 832
Query: 358 EELEVVDEGLCDDGLKPATN-QTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKI 416
+ +V++ C +P + CN C +WV G WS CS C K G + REV C
Sbjct: 833 KTTTLVNDSDCPQASRPEPQVRRCNLHPCQSRWVAGPWSPCSATCEK-GFQHREVTCVYQ 891
Query: 417 ITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVC 476
+ NG C GP+PA +SC W S W C CG G R V C
Sbjct: 892 LQNGTHVATRPLYC---PGPRPAAVQSCEGQDCLSIWEASEWSQCSASCGKGVWKRTVAC 948
Query: 477 YQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGC-DTCLATVRSRVAQC 535
+ G+ + + +P + CE + +W +W+ C TC ++SRV QC
Sbjct: 949 -TNSQGKCD-------ASTRPRAEEACE-DYSGCYEWKTGDWSTCSSTCGKGLQSRVVQC 999
Query: 536 VTK 538
+ K
Sbjct: 1000 MHK 1002
Score = 116 bits (279), Expect = 9e-25
Identities = 57/150 (38%), Positives = 78/150 (52%), Gaps = 2/150 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG G ++R C P G C G ++ CE CP+ FR +QC ++
Sbjct: 555 CSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDR 614
Query: 117 VTFRGKKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQP 176
++ + KK + KPCEL C G ++V+DGT C D+CV G CQ
Sbjct: 615 LSPK-KKGLLTAVVVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYETDLCVHGKCQK 673
Query: 177 VGCDMMLGSNAKEDKCRQCRGNGHNCHTTK 206
+GCD ++GS AKED+C C G+G CH K
Sbjct: 674 IGCDGIIGSAAKEDRCGVCSGDGKTCHLVK 703
Score = 109 bits (262), Expect = 1e-22
Identities = 72/228 (31%), Positives = 95/228 (41%), Gaps = 22/228 (9%)
Query: 377 NQTCNTQACP--PQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKE 429
N+T Q+ P PQ W W CS +CG G R V C +I+ N ++V+D +
Sbjct: 785 NRTAENQSEPEKPQDSLFIWTHSGWEGCSVQCG-GGERRTIVSCTRIV-NKTTTLVNDSD 842
Query: 430 CFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVC-YQKNNGRINVLS 488
C P+P + CN+ W PW PC C G Q R+V C YQ NG
Sbjct: 843 CPQASRPEPQV-RRCNLHPCQSRWVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATR 901
Query: 489 DDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSF 547
C +P Q CE + C + W SEW+ C +C V R C +
Sbjct: 902 PLYCPGPRPAAVQSCEGQDCLSI-WEASEWSQCSASCGKGVWKRTVACTNSQGK------ 954
Query: 548 CSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
C P EE C + C +W WS CS CG G ++R V C
Sbjct: 955 CDASTRPRAEEAC--EDYSGC-YEWKTGDWSTCSSTCGKGLQSRVVQC 999
Score = 109 bits (262), Expect = 1e-22
Identities = 74/243 (30%), Positives = 106/243 (43%), Gaps = 29/243 (11%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC---SEEKPLDRQPCELEPCE 509
W S W+ C CG G++ V C + N +++D +C S +P R+ C L PC+
Sbjct: 804 WTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRR-CNLHPCQ 862
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDK 564
W+ W+ C TC + R CV + + +C P PA + C+
Sbjct: 863 S-RWVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCP-GPRPAAVQSCEGQD 920
Query: 565 LPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPK-EEKYNDSKPC 623
C W A++WS+CS CG G R V C G K D S P+ EE D C
Sbjct: 921 ---CLSIWEASEWSQCSASCGKGVWKRTVACTNSQG----KCDASTRPRAEEACEDYSGC 973
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR--GGKEFSDCPKKSLPDSAGSCNE 681
+W WS C+ +CGKGL+ R V C+ G+ S+CP S P C +
Sbjct: 974 Y--------EWKTGDWSTCSSTCGKGLQSRVVQCMHKVTGRHGSECPALSKPAPYRQCYQ 1025
Query: 682 QSC 684
+ C
Sbjct: 1026 EVC 1028
Score = 94.7 bits (225), Expect = 3e-18
Identities = 63/181 (34%), Positives = 77/181 (42%), Gaps = 20/181 (11%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTC--RSREELEVVDEGLCDDGLKPATNQTCNTQACPPQ 388
WV G +S CSATC G Q R+VTC + + V L G +PA Q+C Q C
Sbjct: 865 WVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCPGPRPAAVQSCEGQDCLSI 924
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W WS+CS CGK G R V C TN +C +P E+C +
Sbjct: 925 WEASEWSQCSASCGK-GVWKRTVAC----TNS------QGKCD--ASTRPRAEEACEDYS 971
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC-SEEKPLDRQPCELEP 507
C W W C CG G Q+R V C K GR EC + KP + C E
Sbjct: 972 GCYEWKTGDWSTCSSTCGKGLQSRVVQCMHKVTGR----HGSECPALSKPAPYRQCYQEV 1027
Query: 508 C 508
C
Sbjct: 1028 C 1028
Score = 76.2 bits (179), Expect = 1e-12
Identities = 41/128 (32%), Positives = 62/128 (48%), Gaps = 11/128 (8%)
Query: 572 WYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDS-KPCEVPEEKC 630
W + W CSV+CG G++ V C + + V+DS+CP+ + + C + C
Sbjct: 804 WTHSGWEGCSVQCGGGERRTIVSCTRIVNKTTTLVNDSDCPQASRPEPQVRRCNL--HPC 861
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVC---LRGGKEFSD----CPKKSLPDSAGSCNEQS 683
S+W A PWS C+ +C KG + R V C L+ G + CP P + SC Q
Sbjct: 862 QSRWVAGPWSPCSATCEKGFQHREVTCVYQLQNGTHVATRPLYCPGPR-PAAVQSCEGQD 920
Query: 684 CEALGEGS 691
C ++ E S
Sbjct: 921 CLSIWEAS 928
Score = 44.0 bits (99), Expect = 0.006
Identities = 22/57 (38%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQAC 385
Y W G++S+CS+TCG G+QSR V C + E C KPA + C + C
Sbjct: 974 YEWKTGDWSTCSSTCGKGLQSRVVQCMHKVTGRHGSE--CPALSKPAPYRQCYQEVC 1028
>L27624-1|AAA20094.1| 235|Homo sapiens tissue factor pathway
inhibitor-2 protein.
Length = 235
Score = 136 bits (328), Expect = 1e-30
Identities = 70/195 (35%), Positives = 95/195 (48%), Gaps = 7/195 (3%)
Query: 1567 FATKEECDDVCVQPSPKDA--CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNAN 1624
F T+ D +P+ +A C LP G C +R+YYD + C QF+YGGC GNAN
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1625 NFDTRELCQSQC-EPARTKDQCSLPIE-RGSCAGNFPRWGFNDETQRCEEFIWGGCEGN- 1681
NF T E C C + C L + C G+ ++ FN + CE+F GGC N
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNR 134
Query: 1682 -SNRFGSEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGG 1740
NRF EA C C P + C P+++G C+ ++F+P C F Y+GCGG
Sbjct: 135 IENRFPDEATCMGFC-APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGG 193
Query: 1741 NQNRFEDEAACASSC 1755
N N F C +C
Sbjct: 194 NDNNFVSREDCKRAC 208
Score = 121 bits (292), Expect = 2e-26
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQPR 1704
C LP++ G C R+ ++ TQ C +F++GGCEGN+N F + AC C +
Sbjct: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKV 95
Query: 1705 CS-QPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGN--QNRFEDEAACASSCPEPFVP 1761
C Q C + ++F+ + C F+ GC N +NRF DEA C C +P
Sbjct: 96 CRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
C P + G C+ +++++ + C F Y GCGGN+N F S+ +C+ C++
Sbjct: 156 SFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
Score = 120 bits (290), Expect = 4e-26
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 6/179 (3%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQ 1579
N C L D G R + +YYD C +F YGG +GN N F T E CDD C ++
Sbjct: 31 NNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 90
Query: 1580 PSPKDACKLP-KVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN--ANNFDTRELCQSQC 1636
PK C+L V C G +++++ C +F GGC N N F C C
Sbjct: 91 KVPK-VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
P + C P + G C+ N R+ FN + C+ F + GC GN N F S CK+ C
Sbjct: 150 APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 102 bits (245), Expect = 1e-20
Identities = 62/210 (29%), Positives = 88/210 (41%), Gaps = 22/210 (10%)
Query: 1745 FEDEAACASSCPEPFV--PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNEN 1802
F EAA + EP ++C LP + G C +++YD + CRQF YGGC GN N
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1803 KFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDAR 1862
F + C+ C I+ V ++E FF C +F +
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFS------- 127
Query: 1863 GGRCAPFQYGGCGGN--TNNFASEEHCQYYC--HFTQDVCQLPMLAGPCNDSIVSWFYDA 1918
GGC N N F E C +C C P G C+ ++ ++++
Sbjct: 128 ---------GGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNP 178
Query: 1919 SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C F Y GCGGNDN F SR++C+ C
Sbjct: 179 RYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 81.4 bits (192), Expect = 3e-14
Identities = 44/129 (34%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Query: 1831 QQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYY 1890
Q+P N+E C D GPC R+ YD C F YGGC GN NNF + E C
Sbjct: 26 QEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDA 85
Query: 1891 C---HFTQDVCQLPM-LAGPCNDSIVSWFYDASRDACSQFAYGGCGGN--DNRFASRDEC 1944
C VC+L + + C S +F++ S C +F GGC N +NRF C
Sbjct: 86 CWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC 145
Query: 1945 ESRCRSGRV 1953
C ++
Sbjct: 146 MGFCAPKKI 154
Score = 71.7 bits (168), Expect = 3e-11
Identities = 27/52 (51%), Positives = 35/52 (67%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+CL PLD GPCRA L +YY+D +SC++F+YGGC G N F T C + C
Sbjct: 35 ICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNG--NRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNV 1600
+++++ C +F+ GG N NRF + C C C PK +G C
Sbjct: 113 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVT 172
Query: 1601 RWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
R+Y++ C F Y GC GN NNF +RE C+ C A K
Sbjct: 173 RYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/76 (32%), Positives = 34/76 (44%)
Query: 2027 FQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRF 2086
F + C C K + C P D G C A + +YYF+ R+C F Y GC G N F
Sbjct: 139 FPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNF 198
Query: 2087 STIAECTEVCKNYIGK 2102
+ +C C + K
Sbjct: 199 VSREDCKRACAKALKK 214
Score = 54.0 bits (124), Expect = 6e-06
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 7/159 (4%)
Query: 1439 EGCGCHTYQFGCCPDGV-TISKGPGLQGCRCEQSQYGCCGDGETHATGPNLGGCDCSTSK 1497
EG + Y + C D I K P + CR + S C +G T NL C
Sbjct: 70 EGNANNFYTWEACDDACWRIEKVPKV--CRLQVSVDDQC-EGSTEKYFFNLSSMTCEKFF 126
Query: 1498 YGCCPDGQTLAEGPKFFGCTDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRF 1555
G C + P C K++ C KD G +Y++ Y C F
Sbjct: 127 SGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAF 186
Query: 1556 WYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGA 1594
Y G GN N F ++E+C C + K K+PK++ A
Sbjct: 187 TYTGCGGNDNNFVSREDCKRACAKALKKKK-KMPKLRFA 224
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 2023 NTGTFQTQEACERSCGAFKDI-NVCLYPLD-PGPCRAYLPKYYFDNERRSCQEFVYGGCH 2080
N F T EAC+ +C + + VC + C KY+F+ +C++F GGCH
Sbjct: 72 NANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCH 131
Query: 2081 GG--PNRFSTIAECTEVC 2096
NRF A C C
Sbjct: 132 RNRIENRFPDEATCMGFC 149
>D29992-1|BAA06272.1| 235|Homo sapiens placental protein 5 (PP5)
protein.
Length = 235
Score = 136 bits (328), Expect = 1e-30
Identities = 70/195 (35%), Positives = 95/195 (48%), Gaps = 7/195 (3%)
Query: 1567 FATKEECDDVCVQPSPKDA--CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNAN 1624
F T+ D +P+ +A C LP G C +R+YYD + C QF+YGGC GNAN
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1625 NFDTRELCQSQC-EPARTKDQCSLPIE-RGSCAGNFPRWGFNDETQRCEEFIWGGCEGN- 1681
NF T E C C + C L + C G+ ++ FN + CE+F GGC N
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNR 134
Query: 1682 -SNRFGSEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGG 1740
NRF EA C C P + C P+++G C+ ++F+P C F Y+GCGG
Sbjct: 135 IENRFPDEATCMGFC-APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGG 193
Query: 1741 NQNRFEDEAACASSC 1755
N N F C +C
Sbjct: 194 NDNNFVSREDCKRAC 208
Score = 121 bits (292), Expect = 2e-26
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQPR 1704
C LP++ G C R+ ++ TQ C +F++GGCEGN+N F + AC C +
Sbjct: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKV 95
Query: 1705 CS-QPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGN--QNRFEDEAACASSCPEPFVP 1761
C Q C + ++F+ + C F+ GC N +NRF DEA C C +P
Sbjct: 96 CRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
C P + G C+ +++++ + C F Y GCGGN+N F S+ +C+ C++
Sbjct: 156 SFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
Score = 120 bits (290), Expect = 4e-26
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 6/179 (3%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQ 1579
N C L D G R + +YYD C +F YGG +GN N F T E CDD C ++
Sbjct: 31 NNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 90
Query: 1580 PSPKDACKLP-KVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN--ANNFDTRELCQSQC 1636
PK C+L V C G +++++ C +F GGC N N F C C
Sbjct: 91 KVPK-VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
P + C P + G C+ N R+ FN + C+ F + GC GN N F S CK+ C
Sbjct: 150 APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 102 bits (245), Expect = 1e-20
Identities = 62/210 (29%), Positives = 88/210 (41%), Gaps = 22/210 (10%)
Query: 1745 FEDEAACASSCPEPFV--PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNEN 1802
F EAA + EP ++C LP + G C +++YD + CRQF YGGC GN N
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1803 KFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDAR 1862
F + C+ C I+ V ++E FF C +F +
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFS------- 127
Query: 1863 GGRCAPFQYGGCGGN--TNNFASEEHCQYYC--HFTQDVCQLPMLAGPCNDSIVSWFYDA 1918
GGC N N F E C +C C P G C+ ++ ++++
Sbjct: 128 ---------GGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNP 178
Query: 1919 SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C F Y GCGGNDN F SR++C+ C
Sbjct: 179 RYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 81.4 bits (192), Expect = 3e-14
Identities = 44/129 (34%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Query: 1831 QQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYY 1890
Q+P N+E C D GPC R+ YD C F YGGC GN NNF + E C
Sbjct: 26 QEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDA 85
Query: 1891 C---HFTQDVCQLPM-LAGPCNDSIVSWFYDASRDACSQFAYGGCGGN--DNRFASRDEC 1944
C VC+L + + C S +F++ S C +F GGC N +NRF C
Sbjct: 86 CWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC 145
Query: 1945 ESRCRSGRV 1953
C ++
Sbjct: 146 MGFCAPKKI 154
Score = 71.7 bits (168), Expect = 3e-11
Identities = 27/52 (51%), Positives = 35/52 (67%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+CL PLD GPCRA L +YY+D +SC++F+YGGC G N F T C + C
Sbjct: 35 ICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNG--NRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNV 1600
+++++ C +F+ GG N NRF + C C C PK +G C
Sbjct: 113 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVT 172
Query: 1601 RWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
R+Y++ C F Y GC GN NNF +RE C+ C A K
Sbjct: 173 RYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/76 (32%), Positives = 34/76 (44%)
Query: 2027 FQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRF 2086
F + C C K + C P D G C A + +YYF+ R+C F Y GC G N F
Sbjct: 139 FPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNF 198
Query: 2087 STIAECTEVCKNYIGK 2102
+ +C C + K
Sbjct: 199 VSREDCKRACAKALKK 214
Score = 54.0 bits (124), Expect = 6e-06
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 7/159 (4%)
Query: 1439 EGCGCHTYQFGCCPDGV-TISKGPGLQGCRCEQSQYGCCGDGETHATGPNLGGCDCSTSK 1497
EG + Y + C D I K P + CR + S C +G T NL C
Sbjct: 70 EGNANNFYTWEACDDACWRIEKVPKV--CRLQVSVDDQC-EGSTEKYFFNLSSMTCEKFF 126
Query: 1498 YGCCPDGQTLAEGPKFFGCTDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRF 1555
G C + P C K++ C KD G +Y++ Y C F
Sbjct: 127 SGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAF 186
Query: 1556 WYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGA 1594
Y G GN N F ++E+C C + K K+PK++ A
Sbjct: 187 TYTGCGGNDNNFVSREDCKRACAKALKKKK-KMPKLRFA 224
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 2023 NTGTFQTQEACERSCGAFKDI-NVCLYPLD-PGPCRAYLPKYYFDNERRSCQEFVYGGCH 2080
N F T EAC+ +C + + VC + C KY+F+ +C++F GGCH
Sbjct: 72 NANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCH 131
Query: 2081 GG--PNRFSTIAECTEVC 2096
NRF A C C
Sbjct: 132 RNRIENRFPDEATCMGFC 149
>BC005330-1|AAH05330.1| 235|Homo sapiens tissue factor pathway
inhibitor 2 protein.
Length = 235
Score = 136 bits (328), Expect = 1e-30
Identities = 70/195 (35%), Positives = 95/195 (48%), Gaps = 7/195 (3%)
Query: 1567 FATKEECDDVCVQPSPKDA--CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNAN 1624
F T+ D +P+ +A C LP G C +R+YYD + C QF+YGGC GNAN
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1625 NFDTRELCQSQC-EPARTKDQCSLPIE-RGSCAGNFPRWGFNDETQRCEEFIWGGCEGN- 1681
NF T E C C + C L + C G+ ++ FN + CE+F GGC N
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNR 134
Query: 1682 -SNRFGSEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGG 1740
NRF EA C C P + C P+++G C+ ++F+P C F Y+GCGG
Sbjct: 135 IENRFPDEATCMGFC-APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGG 193
Query: 1741 NQNRFEDEAACASSC 1755
N N F C +C
Sbjct: 194 NDNNFVSREDCKRAC 208
Score = 121 bits (292), Expect = 2e-26
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQPR 1704
C LP++ G C R+ ++ TQ C +F++GGCEGN+N F + AC C +
Sbjct: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKV 95
Query: 1705 CS-QPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGN--QNRFEDEAACASSCPEPFVP 1761
C Q C + ++F+ + C F+ GC N +NRF DEA C C +P
Sbjct: 96 CRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
C P + G C+ +++++ + C F Y GCGGN+N F S+ +C+ C++
Sbjct: 156 SFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
Score = 120 bits (290), Expect = 4e-26
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 6/179 (3%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQ 1579
N C L D G R + +YYD C +F YGG +GN N F T E CDD C ++
Sbjct: 31 NNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 90
Query: 1580 PSPKDACKLP-KVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN--ANNFDTRELCQSQC 1636
PK C+L V C G +++++ C +F GGC N N F C C
Sbjct: 91 KVPK-VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
P + C P + G C+ N R+ FN + C+ F + GC GN N F S CK+ C
Sbjct: 150 APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 102 bits (245), Expect = 1e-20
Identities = 62/210 (29%), Positives = 88/210 (41%), Gaps = 22/210 (10%)
Query: 1745 FEDEAACASSCPEPFV--PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNEN 1802
F EAA + EP ++C LP + G C +++YD + CRQF YGGC GN N
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1803 KFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDAR 1862
F + C+ C I+ V ++E FF C +F +
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFS------- 127
Query: 1863 GGRCAPFQYGGCGGN--TNNFASEEHCQYYC--HFTQDVCQLPMLAGPCNDSIVSWFYDA 1918
GGC N N F E C +C C P G C+ ++ ++++
Sbjct: 128 ---------GGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNP 178
Query: 1919 SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C F Y GCGGNDN F SR++C+ C
Sbjct: 179 RYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 81.4 bits (192), Expect = 3e-14
Identities = 44/129 (34%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Query: 1831 QQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYY 1890
Q+P N+E C D GPC R+ YD C F YGGC GN NNF + E C
Sbjct: 26 QEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDA 85
Query: 1891 C---HFTQDVCQLPM-LAGPCNDSIVSWFYDASRDACSQFAYGGCGGN--DNRFASRDEC 1944
C VC+L + + C S +F++ S C +F GGC N +NRF C
Sbjct: 86 CWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC 145
Query: 1945 ESRCRSGRV 1953
C ++
Sbjct: 146 MGFCAPKKI 154
Score = 71.7 bits (168), Expect = 3e-11
Identities = 27/52 (51%), Positives = 35/52 (67%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+CL PLD GPCRA L +YY+D +SC++F+YGGC G N F T C + C
Sbjct: 35 ICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNG--NRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNV 1600
+++++ C +F+ GG N NRF + C C C PK +G C
Sbjct: 113 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVT 172
Query: 1601 RWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
R+Y++ C F Y GC GN NNF +RE C+ C A K
Sbjct: 173 RYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/76 (32%), Positives = 34/76 (44%)
Query: 2027 FQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRF 2086
F + C C K + C P D G C A + +YYF+ R+C F Y GC G N F
Sbjct: 139 FPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNF 198
Query: 2087 STIAECTEVCKNYIGK 2102
+ +C C + K
Sbjct: 199 VSREDCKRACAKALKK 214
Score = 54.0 bits (124), Expect = 6e-06
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 7/159 (4%)
Query: 1439 EGCGCHTYQFGCCPDGV-TISKGPGLQGCRCEQSQYGCCGDGETHATGPNLGGCDCSTSK 1497
EG + Y + C D I K P + CR + S C +G T NL C
Sbjct: 70 EGNANNFYTWEACDDACWRIEKVPKV--CRLQVSVDDQC-EGSTEKYFFNLSSMTCEKFF 126
Query: 1498 YGCCPDGQTLAEGPKFFGCTDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRF 1555
G C + P C K++ C KD G +Y++ Y C F
Sbjct: 127 SGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAF 186
Query: 1556 WYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGA 1594
Y G GN N F ++E+C C + K K+PK++ A
Sbjct: 187 TYTGCGGNDNNFVSREDCKRACAKALKKKK-KMPKLRFA 224
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 2023 NTGTFQTQEACERSCGAFKDI-NVCLYPLD-PGPCRAYLPKYYFDNERRSCQEFVYGGCH 2080
N F T EAC+ +C + + VC + C KY+F+ +C++F GGCH
Sbjct: 72 NANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCH 131
Query: 2081 GG--PNRFSTIAECTEVC 2096
NRF A C C
Sbjct: 132 RNRIENRFPDEATCMGFC 149
>AY691946-1|AAU04568.1| 235|Homo sapiens tissue factor pathway
inhibitor 2 protein.
Length = 235
Score = 136 bits (328), Expect = 1e-30
Identities = 70/195 (35%), Positives = 95/195 (48%), Gaps = 7/195 (3%)
Query: 1567 FATKEECDDVCVQPSPKDA--CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNAN 1624
F T+ D +P+ +A C LP G C +R+YYD + C QF+YGGC GNAN
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1625 NFDTRELCQSQC-EPARTKDQCSLPIE-RGSCAGNFPRWGFNDETQRCEEFIWGGCEGN- 1681
NF T E C C + C L + C G+ ++ FN + CE+F GGC N
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNR 134
Query: 1682 -SNRFGSEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGG 1740
NRF EA C C P + C P+++G C+ ++F+P C F Y+GCGG
Sbjct: 135 IENRFPDEATCMGFC-APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGG 193
Query: 1741 NQNRFEDEAACASSC 1755
N N F C +C
Sbjct: 194 NDNNFVSREDCKRAC 208
Score = 121 bits (292), Expect = 2e-26
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQPR 1704
C LP++ G C R+ ++ TQ C +F++GGCEGN+N F + AC C +
Sbjct: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKV 95
Query: 1705 CS-QPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGN--QNRFEDEAACASSCPEPFVP 1761
C Q C + ++F+ + C F+ GC N +NRF DEA C C +P
Sbjct: 96 CRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
C P + G C+ +++++ + C F Y GCGGN+N F S+ +C+ C++
Sbjct: 156 SFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
Score = 120 bits (290), Expect = 4e-26
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 6/179 (3%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQ 1579
N C L D G R + +YYD C +F YGG +GN N F T E CDD C ++
Sbjct: 31 NNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 90
Query: 1580 PSPKDACKLP-KVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN--ANNFDTRELCQSQC 1636
PK C+L V C G +++++ C +F GGC N N F C C
Sbjct: 91 KVPK-VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
P + C P + G C+ N R+ FN + C+ F + GC GN N F S CK+ C
Sbjct: 150 APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 102 bits (245), Expect = 1e-20
Identities = 62/210 (29%), Positives = 88/210 (41%), Gaps = 22/210 (10%)
Query: 1745 FEDEAACASSCPEPFV--PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNEN 1802
F EAA + EP ++C LP + G C +++YD + CRQF YGGC GN N
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1803 KFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDAR 1862
F + C+ C I+ V ++E FF C +F +
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFS------- 127
Query: 1863 GGRCAPFQYGGCGGN--TNNFASEEHCQYYC--HFTQDVCQLPMLAGPCNDSIVSWFYDA 1918
GGC N N F E C +C C P G C+ ++ ++++
Sbjct: 128 ---------GGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNP 178
Query: 1919 SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C F Y GCGGNDN F SR++C+ C
Sbjct: 179 RYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 81.4 bits (192), Expect = 3e-14
Identities = 44/129 (34%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Query: 1831 QQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYY 1890
Q+P N+E C D GPC R+ YD C F YGGC GN NNF + E C
Sbjct: 26 QEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDA 85
Query: 1891 C---HFTQDVCQLPM-LAGPCNDSIVSWFYDASRDACSQFAYGGCGGN--DNRFASRDEC 1944
C VC+L + + C S +F++ S C +F GGC N +NRF C
Sbjct: 86 CWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC 145
Query: 1945 ESRCRSGRV 1953
C ++
Sbjct: 146 MGFCAPKKI 154
Score = 71.7 bits (168), Expect = 3e-11
Identities = 27/52 (51%), Positives = 35/52 (67%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+CL PLD GPCRA L +YY+D +SC++F+YGGC G N F T C + C
Sbjct: 35 ICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNG--NRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNV 1600
+++++ C +F+ GG N NRF + C C C PK +G C
Sbjct: 113 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVT 172
Query: 1601 RWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
R+Y++ C F Y GC GN NNF +RE C+ C A K
Sbjct: 173 RYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/76 (32%), Positives = 34/76 (44%)
Query: 2027 FQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRF 2086
F + C C K + C P D G C A + +YYF+ R+C F Y GC G N F
Sbjct: 139 FPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNF 198
Query: 2087 STIAECTEVCKNYIGK 2102
+ +C C + K
Sbjct: 199 VSREDCKRACAKALKK 214
Score = 54.0 bits (124), Expect = 6e-06
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 7/159 (4%)
Query: 1439 EGCGCHTYQFGCCPDGV-TISKGPGLQGCRCEQSQYGCCGDGETHATGPNLGGCDCSTSK 1497
EG + Y + C D I K P + CR + S C +G T NL C
Sbjct: 70 EGNANNFYTWEACDDACWRIEKVPKV--CRLQVSVDDQC-EGSTEKYFFNLSSMTCEKFF 126
Query: 1498 YGCCPDGQTLAEGPKFFGCTDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRF 1555
G C + P C K++ C KD G +Y++ Y C F
Sbjct: 127 SGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAF 186
Query: 1556 WYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGA 1594
Y G GN N F ++E+C C + K K+PK++ A
Sbjct: 187 TYTGCGGNDNNFVSREDCKRACAKALKKKK-KMPKLRFA 224
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 2023 NTGTFQTQEACERSCGAFKDI-NVCLYPLD-PGPCRAYLPKYYFDNERRSCQEFVYGGCH 2080
N F T EAC+ +C + + VC + C KY+F+ +C++F GGCH
Sbjct: 72 NANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCH 131
Query: 2081 GG--PNRFSTIAECTEVC 2096
NRF A C C
Sbjct: 132 RNRIENRFPDEATCMGFC 149
>AK023228-1|BAB14479.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ13166 fis, clone NT2RP3003701, weakly similar to
F-SPONDIN PRECURSOR. ).
Length = 622
Score = 136 bits (328), Expect = 1e-30
Identities = 91/302 (30%), Positives = 140/302 (46%), Gaps = 24/302 (7%)
Query: 329 YSW-VHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACP 386
++W +G + C+ C G +Q R++TC + + VV + CD P+ Q+CNT C
Sbjct: 2 FTWDPYGPWEGCTKMCQG-LQRRNITCIHKSDHSVVSDKECDHLPLPSFVTQSCNTD-CE 59
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCEKI-ITNGLPSVVDDKECFDLLGPKPALYESCN 445
+W S CS +CG+ G R+ ++ C K I G VDD C D L KP E C+
Sbjct: 60 LRWHVIGKSECSSQCGQ-GYRTLDIHCMKYSIHEGQTVQVDDHYCGDQL--KPPTQELCH 116
Query: 446 VDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCEL 505
+ W S W C + CG G+++R+ C R L+D+EC E + R+ C
Sbjct: 117 GNCVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHR---LADNECQELSRVTRENCNE 173
Query: 506 EPCEGVDWMVSEWTGC-DTCLATVRSRVAQC-VTKDYRVVNSSFCSYHPTPALEEPCDKD 563
C W SEW+ C TC + R C + D+ ++ FC+ P PC+
Sbjct: 174 FSCP--SWAASEWSECLVTCGKGTKQRQVWCQLNVDH--LSDGFCNSSTKPESLSPCE-- 227
Query: 564 KLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
L C W W C+ CG G + R V C ++V+ +D+ C + + +D + C
Sbjct: 228 -LHTC-ASWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVL--EDTECHEASRPSD-RQC 282
Query: 624 EV 625
V
Sbjct: 283 SV 284
Score = 131 bits (316), Expect = 3e-29
Identities = 92/302 (30%), Positives = 130/302 (43%), Gaps = 44/302 (14%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W + +S CS +CGGG +SR+ C + + D C + L T + CN +C P W
Sbjct: 124 WHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNE-CQE-LSRVTRENCNEFSC-PSWA 180
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
WS C CGK GT+ R+V C+ + + + D C KP C + C
Sbjct: 181 ASEWSECLVTCGK-GTKQRQVWCQLNVDH-----LSDGFCNS--STKPESLSPCELH-TC 231
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPCE 509
+W + PW PC CG G Q R V C N VL D EC E +P DRQ C +
Sbjct: 232 ASWQVGPWGPCTTTCGHGYQMRDVKCV--NELASAVLEDTECHEASRPSDRQ-CSV---- 284
Query: 510 GVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQ 569
+C ++R C R+ + S+C++ P PA C C
Sbjct: 285 -------------SCGRGTQARYVSCRDALDRIADESYCAHLPRPAEIWDC----FTPCG 327
Query: 570 VQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEK 629
+W A WS CS CG GK TR+V C + +D++ C E + + C +
Sbjct: 328 -EWQAGDWSPCSASCGHGKTTRQVLCMNYQ----QPIDENYCDPEVRPLMEQECSL--AA 380
Query: 630 CP 631
CP
Sbjct: 381 CP 382
Score = 128 bits (308), Expect = 3e-28
Identities = 87/276 (31%), Positives = 123/276 (44%), Gaps = 27/276 (9%)
Query: 389 WVP-GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY-ESCNV 446
W P G W C+K C G + R + C I SVV DKEC L P P+ +SCN
Sbjct: 4 WDPYGPWEGCTKMC--QGLQRRNITC---IHKSDHSVVSDKECDHL--PLPSFVTQSCNT 56
Query: 447 DAACPTWFISPWKPCDKLCGSGQQTRQVVC--YQKNNGRINVLSDDECSEE-KPLDRQPC 503
D W + C CG G +T + C Y + G+ + D C ++ KP ++ C
Sbjct: 57 DCEL-RWHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELC 115
Query: 504 ELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDK 562
C W SEW+ C +C RSR + C+ + + C + E C++
Sbjct: 116 HGN-CVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGHRLADNECQ-ELSRVTRENCNE 173
Query: 563 DKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP 622
P+ W A++WS+C V CG G K R+V+C +V + D C K P
Sbjct: 174 FSCPS----WAASEWSECLVTCGKGTKQRQVWC----QLNVDHLSDGFCNSSTKPESLSP 225
Query: 623 CEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL 658
CE+ C S W PW CT +CG G + R V C+
Sbjct: 226 CEL--HTCAS-WQVGPWGPCTTTCGHGYQMRDVKCV 258
Score = 104 bits (250), Expect = 3e-21
Identities = 94/361 (26%), Positives = 144/361 (39%), Gaps = 62/361 (17%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
SW G + C+ TCG G Q RDV C + V+++ C + +P+ Q
Sbjct: 233 SWQVGPWGPCTTTCGHGYQMRDVKCVNELASAVLEDTECHEASRPSDRQ----------- 281
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
CS CG+ GT++R V C + L + D+ C L P+PA C
Sbjct: 282 -------CSVSCGR-GTQARYVSCR----DALDRIADESYCAHL--PRPAEIWDCFTP-- 325
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
C W W PC CG G+ TRQV+C + ++P+D C+ E
Sbjct: 326 CGEWQAGDWSPCSASCGHGKTTRQVLCM---------------NYQQPIDENYCDPE--- 367
Query: 510 GVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQ 569
V ++ + C + V Y + + T LE+ ++ P+ +
Sbjct: 368 -VRPLMEQECSLAACPPAHSHFPSSPVQPSYYLSTN----LPLTQKLEDNENQVVHPSVR 422
Query: 570 V-QWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEE 628
QW W CS C G + R V C +G S D ++ P E + PC
Sbjct: 423 GNQWRTGPWGSCSSSCSGGLQHRAVVCQDENGQSASYCDAASKPPELQQCGPGPC----- 477
Query: 629 KCPSKWYAAPWSECTKSCGKGLRFRSVVC-LRGGKEFSD--CPKKSLPDSAGSCNEQSCE 685
+W W EC+++CG G++ R V+C G+ D C + P S C+ +C
Sbjct: 478 ---PQWNYGNWGECSQTCGGGIKSRLVICQFPNGQILEDHNCEIVNKPPSVIQCHMHACP 534
Query: 686 A 686
A
Sbjct: 535 A 535
Score = 95.9 bits (228), Expect = 1e-18
Identities = 72/245 (29%), Positives = 110/245 (44%), Gaps = 28/245 (11%)
Query: 452 TWF-ISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDR---QPCELEP 507
TW PW+ C K+C G Q R + C K++ +V+SD EC + PL Q C +
Sbjct: 3 TWDPYGPWEGCTKMC-QGLQRRNITCIHKSDH--SVVSDKEC-DHLPLPSFVTQSCNTD- 57
Query: 508 CEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRV-----VNSSFCSYHPTPALEEPCD 561
CE + W V + C + C R+ C+ V+ +C P +E C
Sbjct: 58 CE-LRWHVIGKSECSSQCGQGYRTLDIHCMKYSIHEGQTVQVDDHYCGDQLKPPTQELCH 116
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
+ +W+ ++WS+CS CG G+++R +C G ++ D+ C + +
Sbjct: 117 GN---CVFTRWHYSEWSQCSRSCGGGERSRESYCMNNFGH---RLADNECQELSRVTREN 170
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD--CPKKSLPDSAGSC 679
C E CPS W A+ WSEC +CGKG + R V C SD C + P+S C
Sbjct: 171 -CN--EFSCPS-WAASEWSECLVTCGKGTKQRQVWCQLNVDHLSDGFCNSSTKPESLSPC 226
Query: 680 NEQSC 684
+C
Sbjct: 227 ELHTC 231
Score = 93.1 bits (221), Expect = 1e-17
Identities = 85/366 (23%), Positives = 133/366 (36%), Gaps = 63/366 (17%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQW 389
SW +S C TCG G + R V C+ ++ + +G C+ KP + C C W
Sbjct: 178 SWAASEWSECLVTCGKGTKQRQVWCQLN--VDHLSDGFCNSSTKPESLSPCELHTCA-SW 234
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
G W C+ CG G + R+V+C + + +V++D EC + P
Sbjct: 235 QVGPWGPCTTTCGH-GYQMRDVKCVNELAS---AVLEDTECHEASRPSD----------- 279
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQPCELEPC 508
+ C CG G Q R V C + + + C+ +P + C PC
Sbjct: 280 ---------RQCSVSCGRGTQARYVSC---RDALDRIADESYCAHLPRPAEIWDC-FTPC 326
Query: 509 EGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPAC 568
+W +W+ C A C + C + P E CD + P
Sbjct: 327 G--EWQAGDWSPCS----------ASC--GHGKTTRQVLCMNYQQPIDENYCDPEVRPLM 372
Query: 569 QVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVD--DSNCPKEEKYNDSKPCEVP 626
+ +CS+ + F + V +N P +K D++ V
Sbjct: 373 E--------QECSLAACPPAHSH------FPSSPVQPSYYLSTNLPLTQKLEDNENQVVH 418
Query: 627 EEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPKKSLPDSAGSCNEQSCE 685
++W PW C+ SC GL+ R+VVC G+ S C S P C C
Sbjct: 419 PSVRGNQWRTGPWGSCSSSCSGGLQHRAVVCQDENGQSASYCDAASKPPELQQCGPGPCP 478
Query: 686 ALGEGS 691
G+
Sbjct: 479 QWNYGN 484
Score = 79.0 bits (186), Expect = 2e-13
Identities = 46/131 (35%), Positives = 66/131 (50%), Gaps = 15/131 (11%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W G + SCS++C GG+Q R V C+ CD KP Q C C PQW
Sbjct: 426 WRTGPWGSCSSSCSGGLQHRAVVCQDENGQSA---SYCDAASKPPELQQCGPGPC-PQWN 481
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
GNW CS+ CG G +SR V C+ NG +++D C +++ P++ + C++ AC
Sbjct: 482 YGNWGECSQTCG-GGIKSRLVICQ--FPNG--QILEDHNC-EIVNKPPSVIQ-CHMH-AC 533
Query: 451 P---TWFISPW 458
P +W PW
Sbjct: 534 PADVSWHQEPW 544
Score = 63.7 bits (148), Expect = 7e-09
Identities = 47/153 (30%), Positives = 59/153 (38%), Gaps = 15/153 (9%)
Query: 372 LKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
L+ NQ + QW G W CS C G + R V C+ NG + D
Sbjct: 409 LEDNENQVVHPSVRGNQWRTGPWGSCSSSCS-GGLQHRAVVCQD--ENGQSASYCDA--- 462
Query: 432 DLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDE 491
KP + C CP W W C + CG G ++R V+C Q NG+I L D
Sbjct: 463 ---ASKPPELQQCG-PGPCPQWNYGNWGECSQTCGGGIKSRLVIC-QFPNGQI--LEDHN 515
Query: 492 CS-EEKPLDRQPCELEPCEG-VDWMVSEWTGCD 522
C KP C + C V W WT D
Sbjct: 516 CEIVNKPPSVIQCHMHACPADVSWHQEPWTSED 548
Score = 50.4 bits (115), Expect = 7e-05
Identities = 24/67 (35%), Positives = 37/67 (55%), Gaps = 3/67 (4%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP--Q 388
W +GN+ CS TCGGGI+SR V C+ +++++ C+ KP + C+ ACP
Sbjct: 480 WNYGNWGECSQTCGGGIKSRLVICQFPNG-QILEDHNCEIVNKPPSVIQCHMHACPADVS 538
Query: 389 WVPGNWS 395
W W+
Sbjct: 539 WHQEPWT 545
>AF217542-1|AAK13254.1| 235|Homo sapiens tissue factor pathway
inhibitor 2 protein.
Length = 235
Score = 136 bits (328), Expect = 1e-30
Identities = 70/195 (35%), Positives = 95/195 (48%), Gaps = 7/195 (3%)
Query: 1567 FATKEECDDVCVQPSPKDA--CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNAN 1624
F T+ D +P+ +A C LP G C +R+YYD + C QF+YGGC GNAN
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1625 NFDTRELCQSQC-EPARTKDQCSLPIE-RGSCAGNFPRWGFNDETQRCEEFIWGGCEGN- 1681
NF T E C C + C L + C G+ ++ FN + CE+F GGC N
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNR 134
Query: 1682 -SNRFGSEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGG 1740
NRF EA C C P + C P+++G C+ ++F+P C F Y+GCGG
Sbjct: 135 IENRFPDEATCMGFC-APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGG 193
Query: 1741 NQNRFEDEAACASSC 1755
N N F C +C
Sbjct: 194 NDNNFVSREDCKRAC 208
Score = 121 bits (292), Expect = 2e-26
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQPR 1704
C LP++ G C R+ ++ TQ C +F++GGCEGN+N F + AC C +
Sbjct: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKV 95
Query: 1705 CS-QPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGN--QNRFEDEAACASSCPEPFVP 1761
C Q C + ++F+ + C F+ GC N +NRF DEA C C +P
Sbjct: 96 CRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
C P + G C+ +++++ + C F Y GCGGN+N F S+ +C+ C++
Sbjct: 156 SFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
Score = 120 bits (290), Expect = 4e-26
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 6/179 (3%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQ 1579
N C L D G R + +YYD C +F YGG +GN N F T E CDD C ++
Sbjct: 31 NNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 90
Query: 1580 PSPKDACKLP-KVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN--ANNFDTRELCQSQC 1636
PK C+L V C G +++++ C +F GGC N N F C C
Sbjct: 91 KVPK-VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
P + C P + G C+ N R+ FN + C+ F + GC GN N F S CK+ C
Sbjct: 150 APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 102 bits (245), Expect = 1e-20
Identities = 62/210 (29%), Positives = 88/210 (41%), Gaps = 22/210 (10%)
Query: 1745 FEDEAACASSCPEPFV--PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNEN 1802
F EAA + EP ++C LP + G C +++YD + CRQF YGGC GN N
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1803 KFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDAR 1862
F + C+ C I+ V ++E FF C +F +
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFS------- 127
Query: 1863 GGRCAPFQYGGCGGN--TNNFASEEHCQYYC--HFTQDVCQLPMLAGPCNDSIVSWFYDA 1918
GGC N N F E C +C C P G C+ ++ ++++
Sbjct: 128 ---------GGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNP 178
Query: 1919 SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C F Y GCGGNDN F SR++C+ C
Sbjct: 179 RYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 81.4 bits (192), Expect = 3e-14
Identities = 44/129 (34%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Query: 1831 QQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYY 1890
Q+P N+E C D GPC R+ YD C F YGGC GN NNF + E C
Sbjct: 26 QEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDA 85
Query: 1891 C---HFTQDVCQLPM-LAGPCNDSIVSWFYDASRDACSQFAYGGCGGN--DNRFASRDEC 1944
C VC+L + + C S +F++ S C +F GGC N +NRF C
Sbjct: 86 CWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC 145
Query: 1945 ESRCRSGRV 1953
C ++
Sbjct: 146 MGFCAPKKI 154
Score = 71.7 bits (168), Expect = 3e-11
Identities = 27/52 (51%), Positives = 35/52 (67%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+CL PLD GPCRA L +YY+D +SC++F+YGGC G N F T C + C
Sbjct: 35 ICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNG--NRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNV 1600
+++++ C +F+ GG N NRF + C C C PK +G C
Sbjct: 113 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVT 172
Query: 1601 RWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
R+Y++ C F Y GC GN NNF +RE C+ C A K
Sbjct: 173 RYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/76 (32%), Positives = 34/76 (44%)
Query: 2027 FQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRF 2086
F + C C K + C P D G C A + +YYF+ R+C F Y GC G N F
Sbjct: 139 FPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNF 198
Query: 2087 STIAECTEVCKNYIGK 2102
+ +C C + K
Sbjct: 199 VSREDCKRACAKALKK 214
Score = 54.0 bits (124), Expect = 6e-06
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 7/159 (4%)
Query: 1439 EGCGCHTYQFGCCPDGV-TISKGPGLQGCRCEQSQYGCCGDGETHATGPNLGGCDCSTSK 1497
EG + Y + C D I K P + CR + S C +G T NL C
Sbjct: 70 EGNANNFYTWEACDDACWRIEKVPKV--CRLQVSVDDQC-EGSTEKYFFNLSSMTCEKFF 126
Query: 1498 YGCCPDGQTLAEGPKFFGCTDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRF 1555
G C + P C K++ C KD G +Y++ Y C F
Sbjct: 127 SGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAF 186
Query: 1556 WYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGA 1594
Y G GN N F ++E+C C + K K+PK++ A
Sbjct: 187 TYTGCGGNDNNFVSREDCKRACAKALKKKK-KMPKLRFA 224
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 2023 NTGTFQTQEACERSCGAFKDI-NVCLYPLD-PGPCRAYLPKYYFDNERRSCQEFVYGGCH 2080
N F T EAC+ +C + + VC + C KY+F+ +C++F GGCH
Sbjct: 72 NANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCH 131
Query: 2081 GG--PNRFSTIAECTEVC 2096
NRF A C C
Sbjct: 132 RNRIENRFPDEATCMGFC 149
>AC002076-1|AAS02022.1| 235|Homo sapiens unknown protein.
Length = 235
Score = 136 bits (328), Expect = 1e-30
Identities = 70/195 (35%), Positives = 95/195 (48%), Gaps = 7/195 (3%)
Query: 1567 FATKEECDDVCVQPSPKDA--CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNAN 1624
F T+ D +P+ +A C LP G C +R+YYD + C QF+YGGC GNAN
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1625 NFDTRELCQSQC-EPARTKDQCSLPIE-RGSCAGNFPRWGFNDETQRCEEFIWGGCEGN- 1681
NF T E C C + C L + C G+ ++ FN + CE+F GGC N
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNR 134
Query: 1682 -SNRFGSEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGG 1740
NRF EA C C P + C P+++G C+ ++F+P C F Y+GCGG
Sbjct: 135 IENRFPDEATCMGFC-APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGG 193
Query: 1741 NQNRFEDEAACASSC 1755
N N F C +C
Sbjct: 194 NDNNFVSREDCKRAC 208
Score = 121 bits (292), Expect = 2e-26
Identities = 56/175 (32%), Positives = 89/175 (50%), Gaps = 3/175 (1%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQPR 1704
C LP++ G C R+ ++ TQ C +F++GGCEGN+N F + AC C +
Sbjct: 36 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKV 95
Query: 1705 CS-QPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGN--QNRFEDEAACASSCPEPFVP 1761
C Q C + ++F+ + C F+ GC N +NRF DEA C C +P
Sbjct: 96 CRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIP 155
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
C P + G C+ +++++ + C F Y GCGGN+N F S+ +C+ C++
Sbjct: 156 SFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 210
Score = 120 bits (290), Expect = 4e-26
Identities = 62/179 (34%), Positives = 83/179 (46%), Gaps = 6/179 (3%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQ 1579
N C L D G R + +YYD C +F YGG +GN N F T E CDD C ++
Sbjct: 31 NNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 90
Query: 1580 PSPKDACKLP-KVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN--ANNFDTRELCQSQC 1636
PK C+L V C G +++++ C +F GGC N N F C C
Sbjct: 91 KVPK-VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC 149
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
P + C P + G C+ N R+ FN + C+ F + GC GN N F S CK+ C
Sbjct: 150 APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 102 bits (245), Expect = 1e-20
Identities = 62/210 (29%), Positives = 88/210 (41%), Gaps = 22/210 (10%)
Query: 1745 FEDEAACASSCPEPFV--PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNEN 1802
F EAA + EP ++C LP + G C +++YD + CRQF YGGC GN N
Sbjct: 15 FLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNAN 74
Query: 1803 KFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDAR 1862
F + C+ C I+ V ++E FF C +F +
Sbjct: 75 NFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFS------- 127
Query: 1863 GGRCAPFQYGGCGGN--TNNFASEEHCQYYC--HFTQDVCQLPMLAGPCNDSIVSWFYDA 1918
GGC N N F E C +C C P G C+ ++ ++++
Sbjct: 128 ---------GGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNP 178
Query: 1919 SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C F Y GCGGNDN F SR++C+ C
Sbjct: 179 RYRTCDAFTYTGCGGNDNNFVSREDCKRAC 208
Score = 81.4 bits (192), Expect = 3e-14
Identities = 44/129 (34%), Positives = 58/129 (44%), Gaps = 6/129 (4%)
Query: 1831 QQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYY 1890
Q+P N+E C D GPC R+ YD C F YGGC GN NNF + E C
Sbjct: 26 QEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDA 85
Query: 1891 C---HFTQDVCQLPM-LAGPCNDSIVSWFYDASRDACSQFAYGGCGGN--DNRFASRDEC 1944
C VC+L + + C S +F++ S C +F GGC N +NRF C
Sbjct: 86 CWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC 145
Query: 1945 ESRCRSGRV 1953
C ++
Sbjct: 146 MGFCAPKKI 154
Score = 71.7 bits (168), Expect = 3e-11
Identities = 27/52 (51%), Positives = 35/52 (67%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+CL PLD GPCRA L +YY+D +SC++F+YGGC G N F T C + C
Sbjct: 35 ICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 86
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNG--NRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNV 1600
+++++ C +F+ GG N NRF + C C C PK +G C
Sbjct: 113 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVT 172
Query: 1601 RWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
R+Y++ C F Y GC GN NNF +RE C+ C A K
Sbjct: 173 RYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 214
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/76 (32%), Positives = 34/76 (44%)
Query: 2027 FQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRF 2086
F + C C K + C P D G C A + +YYF+ R+C F Y GC G N F
Sbjct: 139 FPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNF 198
Query: 2087 STIAECTEVCKNYIGK 2102
+ +C C + K
Sbjct: 199 VSREDCKRACAKALKK 214
Score = 54.0 bits (124), Expect = 6e-06
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 7/159 (4%)
Query: 1439 EGCGCHTYQFGCCPDGV-TISKGPGLQGCRCEQSQYGCCGDGETHATGPNLGGCDCSTSK 1497
EG + Y + C D I K P + CR + S C +G T NL C
Sbjct: 70 EGNANNFYTWEACDDACWRIEKVPKV--CRLQVSVDDQC-EGSTEKYFFNLSSMTCEKFF 126
Query: 1498 YGCCPDGQTLAEGPKFFGCTDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRF 1555
G C + P C K++ C KD G +Y++ Y C F
Sbjct: 127 SGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAF 186
Query: 1556 WYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGA 1594
Y G GN N F ++E+C C + K K+PK++ A
Sbjct: 187 TYTGCGGNDNNFVSREDCKRACAKALKKKK-KMPKLRFA 224
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 2023 NTGTFQTQEACERSCGAFKDI-NVCLYPLD-PGPCRAYLPKYYFDNERRSCQEFVYGGCH 2080
N F T EAC+ +C + + VC + C KY+F+ +C++F GGCH
Sbjct: 72 NANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCH 131
Query: 2081 GG--PNRFSTIAECTEVC 2096
NRF A C C
Sbjct: 132 RNRIENRFPDEATCMGFC 149
>AY692423-1|AAW47396.1| 270|Homo sapiens ADAMTS6 variant 2 protein.
Length = 270
Score = 135 bits (326), Expect = 2e-30
Identities = 77/229 (33%), Positives = 105/229 (45%), Gaps = 11/229 (4%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNW 394
+S CSATC GG+Q ++V C+ ++ +V CD KP NQ CNT+ CPP+W G+W
Sbjct: 2 WSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCPPEWFIGDW 61
Query: 395 SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWF 454
CSK C G R+R V C + I +D C L +P E CN + P W
Sbjct: 62 LECSKTC-DGGMRTRAVLCIRKIGPSEEETLDYSGC---LTHRPVEKEPCNNQSCPPQWV 117
Query: 455 ISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEGVDW 513
W C CG G + R V+C K++ +C EE KP R C L C W
Sbjct: 118 ALDWSECTPKCGPGFKHRIVLC--KSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPPPRW 175
Query: 514 MVSEWTGCDT-CLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
+ +W C C + R QC++ Y SS C P + C+
Sbjct: 176 VTGDWGQCSAQCGLGQQMRTVQCLS--YTGQASSDCLETVRPPSMQQCE 222
Score = 127 bits (306), Expect = 5e-28
Identities = 74/239 (30%), Positives = 115/239 (48%), Gaps = 21/239 (8%)
Query: 457 PWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQ-PCELEPCEGVDWM 514
PW C C G Q ++VVC + ++ +++ ++ C + KP + Q C EPC +W
Sbjct: 1 PWSECSATCAGGVQRQEVVCKRLDDN--SIVQNNYCDPDSKPPENQRACNTEPCP-PEWF 57
Query: 515 VSEWTGCD-TCLATVRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDKLPACQ 569
+ +W C TC +R+R C+ K + ++ S C H P +EPC+ +C
Sbjct: 58 IGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTH-RPVEKEPCNNQ---SCP 113
Query: 570 VQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEK 629
QW A WS+C+ +CG G K R V C D + + CP+E K C + +
Sbjct: 114 PQWVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPA--AQCPEESKPPVRIRCSL--GR 169
Query: 630 C-PSKWYAAPWSECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCEA 686
C P +W W +C+ CG G + R+V CL G+ SDC + P S C E C++
Sbjct: 170 CPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASSDCLETVRPPSMQQC-ESKCDS 227
Score = 113 bits (272), Expect = 6e-24
Identities = 74/272 (27%), Positives = 117/272 (43%), Gaps = 17/272 (6%)
Query: 394 WSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTW 453
WS CS C G + +EV C+++ N S+V + C D P +CN + P W
Sbjct: 2 WSECSATCA-GGVQRQEVVCKRLDDN---SIVQNNYC-DPDSKPPENQRACNTEPCPPEW 56
Query: 454 FISPWKPCDKLCGSGQQTRQVVCYQK-NNGRINVLSDDECSEEKPLDRQPCELEPCEGVD 512
FI W C K C G +TR V+C +K L C +P++++PC + C
Sbjct: 57 FIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQSCPP-Q 115
Query: 513 WMVSEWTGCDT-CLATVRSRVAQCVTKDY-RVVNSSFCSYHPTPALEEPCDKDKLPACQV 570
W+ +W+ C C + R+ C + D + ++ C P + C + P
Sbjct: 116 WVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPP--P 173
Query: 571 QWYATQWSKCSVECGVGKKTRRVFCGKFDGAS----VMKVDDSNCPKEEKYNDSKPCEVP 626
+W W +CS +CG+G++ R V C + G + + V + + E DS P
Sbjct: 174 RWVTGDWGQCSAQCGLGQQMRTVQCLSYTGQASSDCLETVRPPSMQQCESKCDSTPISNT 233
Query: 627 EE-KCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
EE K +K P K C + FR + C
Sbjct: 234 EECKDVNKVAYCPLVLKFKFCSRAY-FRQMCC 264
Score = 92.7 bits (220), Expect = 1e-17
Identities = 66/212 (31%), Positives = 92/212 (43%), Gaps = 24/212 (11%)
Query: 305 IDENVGVEYEYSLPIEKAPLPTQRY--------SWVHGNFSSCSATCGGGIQSRDVTCRS 356
+D+N V+ Y P K P QR W G++ CS TC GG+++R V C
Sbjct: 23 LDDNSIVQNNYCDPDSKPP-ENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIR 81
Query: 357 R---EELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRC 413
+ E E +D C +P + CN Q+CPPQWV +WS C+ +CG G + R V C
Sbjct: 82 KIGPSEEETLDYSGCLTH-RPVEKEPCNNQSCPPQWVALDWSECTPKCG-PGFKHRIVLC 139
Query: 414 EKIITNGLPSVVDDKECFDLLGPKPALYESCNVD-AACPTWFISPWKPCDKLCGSGQQTR 472
+ ++ L +C + KP + C++ P W W C CG GQQ R
Sbjct: 140 K---SSDLSKTFPAAQCPE--ESKPPVRIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMR 194
Query: 473 QVVCYQKNNGRINVLSDDECSEEKPLDRQPCE 504
V C S D +P Q CE
Sbjct: 195 TVQCLSYT----GQASSDCLETVRPPSMQQCE 222
Score = 70.9 bits (166), Expect = 5e-11
Identities = 44/141 (31%), Positives = 66/141 (46%), Gaps = 19/141 (13%)
Query: 577 WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNC-PKEEKYNDSKPCEVPEEKCPSKWY 635
WS+CS C G + + V C + D S+ V ++ C P + + + C E CP +W+
Sbjct: 2 WSECSATCAGGVQRQEVVCKRLDDNSI--VQNNYCDPDSKPPENQRACNT--EPCPPEWF 57
Query: 636 AAPWSECTKSCGKGLRFRSVVCLR--GGKE-----FSDCPKKSLPDSAGSCNEQSCEALG 688
W EC+K+C G+R R+V+C+R G E +S C P CN QSC
Sbjct: 58 IGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGC-LTHRPVEKEPCNNQSCPP-- 114
Query: 689 EGSGYFTSLDLESTFPEIGSG 709
+ +LD P+ G G
Sbjct: 115 ----QWVALDWSECTPKCGPG 131
>AK092499-1|BAC03906.1| 224|Homo sapiens rase. protein.
Length = 224
Score = 130 bits (315), Expect = 4e-29
Identities = 65/176 (36%), Positives = 87/176 (49%), Gaps = 5/176 (2%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC-EPARTK 1642
DA + P G C +R+YYD + C QF+YGGC GNANNF T E C C +
Sbjct: 23 DAAQEPTDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVP 82
Query: 1643 DQCSLPIE-RGSCAGNFPRWGFNDETQRCEEFIWGGCEGN--SNRFGSEAACKQRCDPPG 1699
C L + C G+ ++ FN + CE+F GGC N NRF EA C C P
Sbjct: 83 KVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFC-APK 141
Query: 1700 TLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
+ C P+++G C+ ++F+P C F Y+GCGGN N F C +C
Sbjct: 142 KIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 197
Score = 116 bits (280), Expect = 7e-25
Identities = 55/177 (31%), Positives = 87/177 (49%), Gaps = 3/177 (1%)
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQ 1702
D P + G C R+ ++ TQ C +F++GGCEGN+N F + AC C +
Sbjct: 23 DAAQEPTDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVP 82
Query: 1703 PRCS-QPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGN--QNRFEDEAACASSCPEPF 1759
C Q C + ++F+ + C F+ GC N +NRF DEA C C
Sbjct: 83 KVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKK 142
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
+P C P + G C+ +++++ + C F Y GCGGN+N F S+ +C+ C++
Sbjct: 143 IPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAK 199
Score = 116 bits (280), Expect = 7e-25
Identities = 59/169 (34%), Positives = 80/169 (47%), Gaps = 6/169 (3%)
Query: 1532 DRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQPSPKDACKLP 1589
D G R + +YYD C +F YGG +GN N F T E CDD C ++ PK C+L
Sbjct: 30 DYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPK-VCRLQ 88
Query: 1590 -KVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN--ANNFDTRELCQSQCEPARTKDQCS 1646
V C G +++++ C +F GGC N N F C C P + C
Sbjct: 89 VSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCY 148
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
P + G C+ N R+ FN + C+ F + GC GN N F S CK+ C
Sbjct: 149 SPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 197
Score = 94.7 bits (225), Expect = 3e-18
Identities = 56/196 (28%), Positives = 80/196 (40%), Gaps = 20/196 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D P + G C +++YD + CRQF YGGC GN N F + C+ C
Sbjct: 18 EAALGDAAQEPTDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWR 77
Query: 1817 IQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGG 1876
I+ V ++E FF C +F + GGC
Sbjct: 78 IEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFS----------------GGCHR 121
Query: 1877 N--TNNFASEEHCQYYC--HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCG 1932
N N F E C +C C P G C+ ++ ++++ C F Y GCG
Sbjct: 122 NRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCG 181
Query: 1933 GNDNRFASRDECESRC 1948
GNDN F SR++C+ C
Sbjct: 182 GNDNNFVSREDCKRAC 197
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNG--NRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNV 1600
+++++ C +F+ GG N NRF + C C C PK +G C
Sbjct: 102 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVT 161
Query: 1601 RWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
R+Y++ C F Y GC GN NNF +RE C+ C A K
Sbjct: 162 RYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 203
Score = 63.7 bits (148), Expect = 7e-09
Identities = 24/48 (50%), Positives = 31/48 (64%)
Query: 2049 PLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
P D GPCRA L +YY+D +SC++F+YGGC G N F T C + C
Sbjct: 28 PTDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 75
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/76 (32%), Positives = 34/76 (44%)
Query: 2027 FQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRF 2086
F + C C K + C P D G C A + +YYF+ R+C F Y GC G N F
Sbjct: 128 FPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNF 187
Query: 2087 STIAECTEVCKNYIGK 2102
+ +C C + K
Sbjct: 188 VSREDCKRACAKALKK 203
Score = 54.0 bits (124), Expect = 6e-06
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 7/159 (4%)
Query: 1439 EGCGCHTYQFGCCPDGV-TISKGPGLQGCRCEQSQYGCCGDGETHATGPNLGGCDCSTSK 1497
EG + Y + C D I K P + CR + S C +G T NL C
Sbjct: 59 EGNANNFYTWEACDDACWRIEKVPKV--CRLQVSVDDQC-EGSTEKYFFNLSSMTCEKFF 115
Query: 1498 YGCCPDGQTLAEGPKFFGCTDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRF 1555
G C + P C K++ C KD G +Y++ Y C F
Sbjct: 116 SGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAF 175
Query: 1556 WYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGA 1594
Y G GN N F ++E+C C + K K+PK++ A
Sbjct: 176 TYTGCGGNDNNFVSREDCKRACAKALKKKK-KMPKLRFA 213
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 2023 NTGTFQTQEACERSCGAFKDI-NVCLYPLD-PGPCRAYLPKYYFDNERRSCQEFVYGGCH 2080
N F T EAC+ +C + + VC + C KY+F+ +C++F GGCH
Sbjct: 61 NANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCH 120
Query: 2081 GG--PNRFSTIAECTEVC 2096
NRF A C C
Sbjct: 121 RNRIENRFPDEATCMGFC 138
>AK128469-1|BAC87455.1| 327|Homo sapiens protein ( Homo sapiens
cDNA FLJ46613 fis, clone TKIDN2011160, moderately
similar to ADAM-TS 3 precursor (EC 3.4.24.-). ).
Length = 327
Score = 129 bits (312), Expect = 9e-29
Identities = 71/187 (37%), Positives = 96/187 (51%), Gaps = 5/187 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSR+CGGGV S+ R C P G C G +Y C +++CP DFRA+QCA+ N+
Sbjct: 87 CSRSCGGGVRSRSRSCNNPSPAYGGRLCLGPMFEYQVCNSEECPGTYEDFRAQQCAKRNS 146
Query: 117 V-TFRGKKYRWVPYLKV--SKPCELTCMQHGDRFYYRHKEKVIDGTRCN-DDSFDVCVDG 172
+ K+ WVPY ++ CEL C + V DGTRC+ D + VC G
Sbjct: 147 YYVHQNAKHSWVPYEPDDDAQKCELICQSADTGDVVFMNQVVHDGTRCSYRDPYSVCARG 206
Query: 173 VCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIY 232
C PVGCD +GS +DKC C G+ +C T K + + G ++ IP GA I
Sbjct: 207 ECVPVGCDKEVGSMKADDKCGVCGGDNSHCRTVKGTLGKASKQAGALKLVQIPAGARHIQ 266
Query: 233 ITEIEPS 239
I +E S
Sbjct: 267 IEALEKS 273
Score = 41.5 bits (93), Expect = 0.032
Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN-QTCNTQACPPQ 388
SW F SCS +CGGG++SR +C + LC L P Q CN++ CP
Sbjct: 80 SWT--KFGSCSRSCGGGVRSRSRSCNNPS--PAYGGRLC---LGPMFEYQVCNSEECPGT 132
Query: 389 WVPGNWSRCSKR 400
+ +C+KR
Sbjct: 133 YEDFRAQQCAKR 144
>AK131344-1|BAD18500.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ16363 fis, clone THYMU2031139, weakly similar
to Homo sapiens zinc metalloprotease ADAMTS7 (ADAMTS7)
mRNA. ).
Length = 502
Score = 128 bits (310), Expect = 2e-28
Identities = 67/187 (35%), Positives = 97/187 (51%), Gaps = 3/187 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CSRTCG G ++R C P G C G ++ CE CP+ FR +QC ++
Sbjct: 312 CSRTCGTGARFRQRKCDNPPPGPGGTHCPGASVEHAVCENLPCPKGLPSFRDQQCQAHDR 371
Query: 117 VTFRGKKYRWVPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRCNDDSFDVCVDGVCQP 176
++ + KK + KPCEL C G ++V+DGT C D+CV G CQ
Sbjct: 372 LSPK-KKGLLTAVVVDDKPCELYCSPLGKESPLLVADRVLDGTPCGPYETDLCVHGKCQK 430
Query: 177 VGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYNDILLIPEGATTIYITEI 236
+GCD ++GS AKED+C C G+G CH K + GY + +IP GA I + E
Sbjct: 431 IGCDGIIGSAAKEDRCGVCSGDGKTCHLAKGDF-SHARGTGYIEAAVIPAGARRIRVVED 489
Query: 237 EPSNNYL 243
+P++++L
Sbjct: 490 KPAHSFL 496
>M59499-1|AAA59526.1| 304|Homo sapiens lipoprotein-associated
coagulation inhibitor protein.
Length = 304
Score = 120 bits (290), Expect = 4e-26
Identities = 70/214 (32%), Positives = 93/214 (43%), Gaps = 27/214 (12%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFV---- 1760
C+ + G C ++F+ +C F Y GC GNQNRFE C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1761 --------PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECES 1812
PD C L + G C Y ++FY+ K+C +F YGGC GN N F + EC++
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1813 RCSEIQXXXXXXXXXVQ---------PQQPG-PENSEF-----CFFETDPGPCTQFETRW 1857
C + Q PQ P EF C D G C E R+
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1858 SYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
Y++ G+C PF+Y GCGGN NNF S++ C C
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
Score = 106 bits (255), Expect = 7e-22
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCS 1815
P + C A+ G C +++F++ ++C +F YGGC GN+N+F S EC+ C+
Sbjct: 46 PLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCT 105
Query: 1816 EIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCG 1875
+Q ++P +FCF E DPG C + TR+ Y+ + +C F+YGGC
Sbjct: 106 R-DNANRIIKTTLQQEKP-----DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCL 159
Query: 1876 GNTNNFASEEHCQYYC 1891
GN NNF + E C+ C
Sbjct: 160 GNMNNFETLEECKNIC 175
Score = 94.3 bits (224), Expect = 4e-18
Identities = 48/135 (35%), Positives = 73/135 (54%), Gaps = 14/135 (10%)
Query: 1517 TDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECD 1574
T++P K + C+ D G + +++++ C F YGG +GN NRF + EEC
Sbjct: 42 TELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECK 101
Query: 1575 DVC------------VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN 1622
+C +Q D C L + G C GY R++Y+++ +QC +F YGGCLGN
Sbjct: 102 KMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGN 161
Query: 1623 ANNFDTRELCQSQCE 1637
NNF+T E C++ CE
Sbjct: 162 MNNFETLEECKNICE 176
Score = 91.1 bits (216), Expect = 4e-17
Identities = 64/220 (29%), Positives = 92/220 (41%), Gaps = 46/220 (20%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK--- 1642
C G C R++++ QC +F+YGGC GN N F++ E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1643 ---------DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQ 1693
D C L + G C G R+ +N++T++CE F +GGC GN N F + CK
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1694 RC-DPPGTLQPRCSQPREQGGCNET---------------AAVWWFSPAE-GRCRP---- 1732
C D P Q + + N + W +PA+ G CR
Sbjct: 174 ICEDGPNGFQVD-NYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENR 232
Query: 1733 FY------------YSGCGGNQNRFEDEAACASSCPEPFV 1760
FY YSGCGGN+N F + C +C + F+
Sbjct: 233 FYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFI 272
Score = 84.2 bits (199), Expect = 5e-15
Identities = 44/126 (34%), Positives = 57/126 (45%), Gaps = 14/126 (11%)
Query: 1840 FCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-------- 1891
FC F+ D GPC R+ ++ +C F YGGC GN N F S E C+ C
Sbjct: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRI 112
Query: 1892 ------HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
D C L G C I +FY+ C +F YGGC GN N F + +EC+
Sbjct: 113 IKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECK 172
Query: 1946 SRCRSG 1951
+ C G
Sbjct: 173 NICEDG 178
Score = 83.4 bits (197), Expect = 8e-15
Identities = 67/216 (31%), Positives = 89/216 (41%), Gaps = 44/216 (20%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG----- 1699
C+ + G C R+ FN T++CEEFI+GGCEGN NRF S CK+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1700 --TLQPR----CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
TLQ C + G C ++++ +C F Y GC GN N FE C +
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1754 SC---PEPFVPD----------LCTLPAETGECANYE---EKWFYDTSEK-RCR----QF 1792
C P F D P T + +E W +++ CR +F
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1793 YY------------GGCGGNENKFNSQIECESRCSE 1816
YY GCGGNEN F S+ EC C +
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/51 (43%), Positives = 35/51 (68%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C + D GPC+A + +++F+ R C+EF+YGGC G NRF ++ EC ++C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
C DPG CR Y+ +Y+++N+ + C+ F YGGC G N F T+ EC +C++
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
Score = 52.8 bits (121), Expect = 1e-05
Identities = 21/60 (35%), Positives = 31/60 (51%)
Query: 1898 CQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRVAEVS 1957
C P G C + ++Y++ C F Y GCGGN+N F S+ EC C+ G + +S
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRIS 276
Score = 52.4 bits (120), Expect = 2e-05
Identities = 21/52 (40%), Positives = 29/52 (55%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
CL P D G CRA ++Y+++ C+ F Y GC G N F++ EC CK
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
Score = 42.3 bits (95), Expect = 0.018
Identities = 20/51 (39%), Positives = 24/51 (47%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C DRG R +YY+ G C F Y G GN N F +K+EC C
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
>M58650-1|AAA59480.1| 304|Homo sapiens lipoprotein associated
coagulation inhibitor protein.
Length = 304
Score = 120 bits (290), Expect = 4e-26
Identities = 70/214 (32%), Positives = 93/214 (43%), Gaps = 27/214 (12%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFV---- 1760
C+ + G C ++F+ +C F Y GC GNQNRFE C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1761 --------PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECES 1812
PD C L + G C Y ++FY+ K+C +F YGGC GN N F + EC++
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1813 RCSEIQXXXXXXXXXVQ---------PQQPG-PENSEF-----CFFETDPGPCTQFETRW 1857
C + Q PQ P EF C D G C E R+
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1858 SYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
Y++ G+C PF+Y GCGGN NNF S++ C C
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
Score = 106 bits (255), Expect = 7e-22
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCS 1815
P + C A+ G C +++F++ ++C +F YGGC GN+N+F S EC+ C+
Sbjct: 46 PLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCT 105
Query: 1816 EIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCG 1875
+Q ++P +FCF E DPG C + TR+ Y+ + +C F+YGGC
Sbjct: 106 R-DNANRIIKTTLQQEKP-----DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCL 159
Query: 1876 GNTNNFASEEHCQYYC 1891
GN NNF + E C+ C
Sbjct: 160 GNMNNFETLEECKNIC 175
Score = 94.3 bits (224), Expect = 4e-18
Identities = 48/135 (35%), Positives = 73/135 (54%), Gaps = 14/135 (10%)
Query: 1517 TDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECD 1574
T++P K + C+ D G + +++++ C F YGG +GN NRF + EEC
Sbjct: 42 TELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECK 101
Query: 1575 DVC------------VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN 1622
+C +Q D C L + G C GY R++Y+++ +QC +F YGGCLGN
Sbjct: 102 KMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGN 161
Query: 1623 ANNFDTRELCQSQCE 1637
NNF+T E C++ CE
Sbjct: 162 MNNFETLEECKNICE 176
Score = 91.1 bits (216), Expect = 4e-17
Identities = 64/220 (29%), Positives = 92/220 (41%), Gaps = 46/220 (20%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK--- 1642
C G C R++++ QC +F+YGGC GN N F++ E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1643 ---------DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQ 1693
D C L + G C G R+ +N++T++CE F +GGC GN N F + CK
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1694 RC-DPPGTLQPRCSQPREQGGCNET---------------AAVWWFSPAE-GRCRP---- 1732
C D P Q + + N + W +PA+ G CR
Sbjct: 174 ICEDGPNGFQVD-NYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENR 232
Query: 1733 FY------------YSGCGGNQNRFEDEAACASSCPEPFV 1760
FY YSGCGGN+N F + C +C + F+
Sbjct: 233 FYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFI 272
Score = 84.2 bits (199), Expect = 5e-15
Identities = 44/126 (34%), Positives = 57/126 (45%), Gaps = 14/126 (11%)
Query: 1840 FCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-------- 1891
FC F+ D GPC R+ ++ +C F YGGC GN N F S E C+ C
Sbjct: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRI 112
Query: 1892 ------HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
D C L G C I +FY+ C +F YGGC GN N F + +EC+
Sbjct: 113 IKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECK 172
Query: 1946 SRCRSG 1951
+ C G
Sbjct: 173 NICEDG 178
Score = 83.4 bits (197), Expect = 8e-15
Identities = 67/216 (31%), Positives = 89/216 (41%), Gaps = 44/216 (20%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG----- 1699
C+ + G C R+ FN T++CEEFI+GGCEGN NRF S CK+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1700 --TLQPR----CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
TLQ C + G C ++++ +C F Y GC GN N FE C +
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1754 SC---PEPFVPD----------LCTLPAETGECANYE---EKWFYDTSEK-RCR----QF 1792
C P F D P T + +E W +++ CR +F
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1793 YY------------GGCGGNENKFNSQIECESRCSE 1816
YY GCGGNEN F S+ EC C +
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/51 (43%), Positives = 35/51 (68%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C + D GPC+A + +++F+ R C+EF+YGGC G NRF ++ EC ++C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
C DPG CR Y+ +Y+++N+ + C+ F YGGC G N F T+ EC +C++
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
Score = 52.8 bits (121), Expect = 1e-05
Identities = 21/60 (35%), Positives = 31/60 (51%)
Query: 1898 CQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRVAEVS 1957
C P G C + ++Y++ C F Y GCGGN+N F S+ EC C+ G + +S
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRIS 276
Score = 52.4 bits (120), Expect = 2e-05
Identities = 21/52 (40%), Positives = 29/52 (55%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
CL P D G CRA ++Y+++ C+ F Y GC G N F++ EC CK
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
Score = 42.3 bits (95), Expect = 0.018
Identities = 20/51 (39%), Positives = 24/51 (47%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C DRG R +YY+ G C F Y G GN N F +K+EC C
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
>J03225-1|AAA52022.1| 304|Homo sapiens TFPI protein.
Length = 304
Score = 120 bits (290), Expect = 4e-26
Identities = 70/214 (32%), Positives = 93/214 (43%), Gaps = 27/214 (12%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFV---- 1760
C+ + G C ++F+ +C F Y GC GNQNRFE C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1761 --------PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECES 1812
PD C L + G C Y ++FY+ K+C +F YGGC GN N F + EC++
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1813 RCSEIQXXXXXXXXXVQ---------PQQPG-PENSEF-----CFFETDPGPCTQFETRW 1857
C + Q PQ P EF C D G C E R+
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1858 SYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
Y++ G+C PF+Y GCGGN NNF S++ C C
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
Score = 106 bits (255), Expect = 7e-22
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCS 1815
P + C A+ G C +++F++ ++C +F YGGC GN+N+F S EC+ C+
Sbjct: 46 PLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCT 105
Query: 1816 EIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCG 1875
+Q ++P +FCF E DPG C + TR+ Y+ + +C F+YGGC
Sbjct: 106 R-DNANRIIKTTLQQEKP-----DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCL 159
Query: 1876 GNTNNFASEEHCQYYC 1891
GN NNF + E C+ C
Sbjct: 160 GNMNNFETLEECKNIC 175
Score = 94.3 bits (224), Expect = 4e-18
Identities = 48/135 (35%), Positives = 73/135 (54%), Gaps = 14/135 (10%)
Query: 1517 TDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECD 1574
T++P K + C+ D G + +++++ C F YGG +GN NRF + EEC
Sbjct: 42 TELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECK 101
Query: 1575 DVC------------VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN 1622
+C +Q D C L + G C GY R++Y+++ +QC +F YGGCLGN
Sbjct: 102 KMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGN 161
Query: 1623 ANNFDTRELCQSQCE 1637
NNF+T E C++ CE
Sbjct: 162 MNNFETLEECKNICE 176
Score = 91.1 bits (216), Expect = 4e-17
Identities = 64/220 (29%), Positives = 92/220 (41%), Gaps = 46/220 (20%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK--- 1642
C G C R++++ QC +F+YGGC GN N F++ E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1643 ---------DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQ 1693
D C L + G C G R+ +N++T++CE F +GGC GN N F + CK
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1694 RC-DPPGTLQPRCSQPREQGGCNET---------------AAVWWFSPAE-GRCRP---- 1732
C D P Q + + N + W +PA+ G CR
Sbjct: 174 ICEDGPNGFQVD-NYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENR 232
Query: 1733 FY------------YSGCGGNQNRFEDEAACASSCPEPFV 1760
FY YSGCGGN+N F + C +C + F+
Sbjct: 233 FYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFI 272
Score = 84.2 bits (199), Expect = 5e-15
Identities = 44/126 (34%), Positives = 57/126 (45%), Gaps = 14/126 (11%)
Query: 1840 FCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-------- 1891
FC F+ D GPC R+ ++ +C F YGGC GN N F S E C+ C
Sbjct: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRI 112
Query: 1892 ------HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
D C L G C I +FY+ C +F YGGC GN N F + +EC+
Sbjct: 113 IKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECK 172
Query: 1946 SRCRSG 1951
+ C G
Sbjct: 173 NICEDG 178
Score = 83.4 bits (197), Expect = 8e-15
Identities = 67/216 (31%), Positives = 89/216 (41%), Gaps = 44/216 (20%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG----- 1699
C+ + G C R+ FN T++CEEFI+GGCEGN NRF S CK+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1700 --TLQPR----CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
TLQ C + G C ++++ +C F Y GC GN N FE C +
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1754 SC---PEPFVPD----------LCTLPAETGECANYE---EKWFYDTSEK-RCR----QF 1792
C P F D P T + +E W +++ CR +F
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1793 YY------------GGCGGNENKFNSQIECESRCSE 1816
YY GCGGNEN F S+ EC C +
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/51 (43%), Positives = 35/51 (68%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C + D GPC+A + +++F+ R C+EF+YGGC G NRF ++ EC ++C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
C DPG CR Y+ +Y+++N+ + C+ F YGGC G N F T+ EC +C++
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
Score = 52.8 bits (121), Expect = 1e-05
Identities = 21/60 (35%), Positives = 31/60 (51%)
Query: 1898 CQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRVAEVS 1957
C P G C + ++Y++ C F Y GCGGN+N F S+ EC C+ G + +S
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRIS 276
Score = 52.4 bits (120), Expect = 2e-05
Identities = 21/52 (40%), Positives = 29/52 (55%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
CL P D G CRA ++Y+++ C+ F Y GC G N F++ EC CK
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
Score = 42.3 bits (95), Expect = 0.018
Identities = 20/51 (39%), Positives = 24/51 (47%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C DRG R +YY+ G C F Y G GN N F +K+EC C
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
>AY263365-1|AAO89075.1| 304|Homo sapiens tissue factor pathway
inhibitor (lipoprotein-associated coagulation inhibitor)
protein.
Length = 304
Score = 120 bits (290), Expect = 4e-26
Identities = 70/214 (32%), Positives = 93/214 (43%), Gaps = 27/214 (12%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFV---- 1760
C+ + G C ++F+ +C F Y GC GNQNRFE C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1761 --------PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECES 1812
PD C L + G C Y ++FY+ K+C +F YGGC GN N F + EC++
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1813 RCSEIQXXXXXXXXXVQ---------PQQPG-PENSEF-----CFFETDPGPCTQFETRW 1857
C + Q PQ P EF C D G C E R+
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1858 SYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
Y++ G+C PF+Y GCGGN NNF S++ C C
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
Score = 106 bits (255), Expect = 7e-22
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCS 1815
P + C A+ G C +++F++ ++C +F YGGC GN+N+F S EC+ C+
Sbjct: 46 PLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCT 105
Query: 1816 EIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCG 1875
+Q ++P +FCF E DPG C + TR+ Y+ + +C F+YGGC
Sbjct: 106 R-DNANRIIKTTLQQEKP-----DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCL 159
Query: 1876 GNTNNFASEEHCQYYC 1891
GN NNF + E C+ C
Sbjct: 160 GNMNNFETLEECKNIC 175
Score = 94.3 bits (224), Expect = 4e-18
Identities = 48/135 (35%), Positives = 73/135 (54%), Gaps = 14/135 (10%)
Query: 1517 TDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECD 1574
T++P K + C+ D G + +++++ C F YGG +GN NRF + EEC
Sbjct: 42 TELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECK 101
Query: 1575 DVC------------VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN 1622
+C +Q D C L + G C GY R++Y+++ +QC +F YGGCLGN
Sbjct: 102 KMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGN 161
Query: 1623 ANNFDTRELCQSQCE 1637
NNF+T E C++ CE
Sbjct: 162 MNNFETLEECKNICE 176
Score = 91.1 bits (216), Expect = 4e-17
Identities = 64/220 (29%), Positives = 92/220 (41%), Gaps = 46/220 (20%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK--- 1642
C G C R++++ QC +F+YGGC GN N F++ E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1643 ---------DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQ 1693
D C L + G C G R+ +N++T++CE F +GGC GN N F + CK
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1694 RC-DPPGTLQPRCSQPREQGGCNET---------------AAVWWFSPAE-GRCRP---- 1732
C D P Q + + N + W +PA+ G CR
Sbjct: 174 ICEDGPNGFQVD-NYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENR 232
Query: 1733 FY------------YSGCGGNQNRFEDEAACASSCPEPFV 1760
FY YSGCGGN+N F + C +C + F+
Sbjct: 233 FYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFI 272
Score = 84.2 bits (199), Expect = 5e-15
Identities = 44/126 (34%), Positives = 57/126 (45%), Gaps = 14/126 (11%)
Query: 1840 FCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-------- 1891
FC F+ D GPC R+ ++ +C F YGGC GN N F S E C+ C
Sbjct: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRI 112
Query: 1892 ------HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
D C L G C I +FY+ C +F YGGC GN N F + +EC+
Sbjct: 113 IKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECK 172
Query: 1946 SRCRSG 1951
+ C G
Sbjct: 173 NICEDG 178
Score = 83.4 bits (197), Expect = 8e-15
Identities = 67/216 (31%), Positives = 89/216 (41%), Gaps = 44/216 (20%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG----- 1699
C+ + G C R+ FN T++CEEFI+GGCEGN NRF S CK+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1700 --TLQPR----CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
TLQ C + G C ++++ +C F Y GC GN N FE C +
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1754 SC---PEPFVPD----------LCTLPAETGECANYE---EKWFYDTSEK-RCR----QF 1792
C P F D P T + +E W +++ CR +F
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1793 YY------------GGCGGNENKFNSQIECESRCSE 1816
YY GCGGNEN F S+ EC C +
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/51 (43%), Positives = 35/51 (68%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C + D GPC+A + +++F+ R C+EF+YGGC G NRF ++ EC ++C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
C DPG CR Y+ +Y+++N+ + C+ F YGGC G N F T+ EC +C++
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
Score = 52.8 bits (121), Expect = 1e-05
Identities = 21/60 (35%), Positives = 31/60 (51%)
Query: 1898 CQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRVAEVS 1957
C P G C + ++Y++ C F Y GCGGN+N F S+ EC C+ G + +S
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRIS 276
Score = 52.4 bits (120), Expect = 2e-05
Identities = 21/52 (40%), Positives = 29/52 (55%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
CL P D G CRA ++Y+++ C+ F Y GC G N F++ EC CK
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
Score = 42.3 bits (95), Expect = 0.018
Identities = 20/51 (39%), Positives = 24/51 (47%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C DRG R +YY+ G C F Y G GN N F +K+EC C
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
>AC007319-2|AAY14807.1| 304|Homo sapiens unknown protein.
Length = 304
Score = 120 bits (290), Expect = 4e-26
Identities = 70/214 (32%), Positives = 93/214 (43%), Gaps = 27/214 (12%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFV---- 1760
C+ + G C ++F+ +C F Y GC GNQNRFE C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1761 --------PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECES 1812
PD C L + G C Y ++FY+ K+C +F YGGC GN N F + EC++
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1813 RCSEIQXXXXXXXXXVQ---------PQQPG-PENSEF-----CFFETDPGPCTQFETRW 1857
C + Q PQ P EF C D G C E R+
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1858 SYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
Y++ G+C PF+Y GCGGN NNF S++ C C
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
Score = 106 bits (255), Expect = 7e-22
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCS 1815
P + C A+ G C +++F++ ++C +F YGGC GN+N+F S EC+ C+
Sbjct: 46 PLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCT 105
Query: 1816 EIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCG 1875
+Q ++P +FCF E DPG C + TR+ Y+ + +C F+YGGC
Sbjct: 106 R-DNANRIIKTTLQQEKP-----DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCL 159
Query: 1876 GNTNNFASEEHCQYYC 1891
GN NNF + E C+ C
Sbjct: 160 GNMNNFETLEECKNIC 175
Score = 94.3 bits (224), Expect = 4e-18
Identities = 48/135 (35%), Positives = 73/135 (54%), Gaps = 14/135 (10%)
Query: 1517 TDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECD 1574
T++P K + C+ D G + +++++ C F YGG +GN NRF + EEC
Sbjct: 42 TELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECK 101
Query: 1575 DVC------------VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN 1622
+C +Q D C L + G C GY R++Y+++ +QC +F YGGCLGN
Sbjct: 102 KMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGN 161
Query: 1623 ANNFDTRELCQSQCE 1637
NNF+T E C++ CE
Sbjct: 162 MNNFETLEECKNICE 176
Score = 91.1 bits (216), Expect = 4e-17
Identities = 64/220 (29%), Positives = 92/220 (41%), Gaps = 46/220 (20%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK--- 1642
C G C R++++ QC +F+YGGC GN N F++ E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1643 ---------DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQ 1693
D C L + G C G R+ +N++T++CE F +GGC GN N F + CK
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1694 RC-DPPGTLQPRCSQPREQGGCNET---------------AAVWWFSPAE-GRCRP---- 1732
C D P Q + + N + W +PA+ G CR
Sbjct: 174 ICEDGPNGFQVD-NYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENR 232
Query: 1733 FY------------YSGCGGNQNRFEDEAACASSCPEPFV 1760
FY YSGCGGN+N F + C +C + F+
Sbjct: 233 FYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFI 272
Score = 84.2 bits (199), Expect = 5e-15
Identities = 44/126 (34%), Positives = 57/126 (45%), Gaps = 14/126 (11%)
Query: 1840 FCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-------- 1891
FC F+ D GPC R+ ++ +C F YGGC GN N F S E C+ C
Sbjct: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRI 112
Query: 1892 ------HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
D C L G C I +FY+ C +F YGGC GN N F + +EC+
Sbjct: 113 IKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECK 172
Query: 1946 SRCRSG 1951
+ C G
Sbjct: 173 NICEDG 178
Score = 83.4 bits (197), Expect = 8e-15
Identities = 67/216 (31%), Positives = 89/216 (41%), Gaps = 44/216 (20%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG----- 1699
C+ + G C R+ FN T++CEEFI+GGCEGN NRF S CK+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1700 --TLQPR----CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
TLQ C + G C ++++ +C F Y GC GN N FE C +
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1754 SC---PEPFVPD----------LCTLPAETGECANYE---EKWFYDTSEK-RCR----QF 1792
C P F D P T + +E W +++ CR +F
Sbjct: 174 ICEDGPNGFQVDNYGTQLNAVNNSLTPQSTKVPSLFEFHGPSWCLTPADRGLCRANENRF 233
Query: 1793 YY------------GGCGGNENKFNSQIECESRCSE 1816
YY GCGGNEN F S+ EC C +
Sbjct: 234 YYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKK 269
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/51 (43%), Positives = 35/51 (68%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C + D GPC+A + +++F+ R C+EF+YGGC G NRF ++ EC ++C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
C DPG CR Y+ +Y+++N+ + C+ F YGGC G N F T+ EC +C++
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
Score = 52.8 bits (121), Expect = 1e-05
Identities = 21/60 (35%), Positives = 31/60 (51%)
Query: 1898 CQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRVAEVS 1957
C P G C + ++Y++ C F Y GCGGN+N F S+ EC C+ G + +S
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACKKGFIQRIS 276
Score = 52.4 bits (120), Expect = 2e-05
Identities = 21/52 (40%), Positives = 29/52 (55%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
CL P D G CRA ++Y+++ C+ F Y GC G N F++ EC CK
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRACK 268
Score = 42.3 bits (95), Expect = 0.018
Identities = 20/51 (39%), Positives = 24/51 (47%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C DRG R +YY+ G C F Y G GN N F +K+EC C
Sbjct: 217 CLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGNENNFTSKQECLRAC 267
>AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein.
Length = 1023
Score = 120 bits (289), Expect = 6e-26
Identities = 83/256 (32%), Positives = 111/256 (43%), Gaps = 19/256 (7%)
Query: 376 TNQTCNTQACPPQ---WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFD 432
TN T PPQ W PGNWS CS CG G R + +C ++ NG V + C
Sbjct: 744 TNSNDPTGEPPPQEPFWEPGNWSHCSATCGHLGARIQRPQC--VMANG--QEVSEALCDH 799
Query: 433 LLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDE 491
L P A +E CN+ WF S W C CG G +RQV C + K NG + V+S
Sbjct: 800 LQKPL-AGFEPCNIRDCPARWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRA 858
Query: 492 CS-EEKPLDRQPCELEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSY 550
C+ +++PL R+PC PC V W C R+ Q T + S C
Sbjct: 859 CAPKDRPLGRKPCFGHPC--VQW--EPGNRCPGRCMGRAVRMQQRHTACQHNSSDSNCDD 914
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSN 610
P L C AC V W+ W C+ CG G ++R+V C S V +
Sbjct: 915 RKRPTLRRNCTSG---ACDVCWHTGPWKPCTAACGRGFQSRKVDC--IHTRSCKPVAKRH 969
Query: 611 CPKEEKYNDSKPCEVP 626
C +++K + C P
Sbjct: 970 CVQKKKPISWRHCLGP 985
Score = 110 bits (264), Expect = 6e-23
Identities = 66/184 (35%), Positives = 91/184 (49%), Gaps = 10/184 (5%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWV 390
W G++ CSATCG GIQ+RDV C E E D+ KP Q CN CPP W
Sbjct: 39 WHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPEECRDE--KPHALQACNQFDCPPGWH 96
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
W +CS+ CG GT++R V C +++T+G + D+ C GPK + ++SC
Sbjct: 97 IEEWQQCSRTCG-GGTQNRRVTCRQLLTDGSFLNLSDELC---QGPKASSHKSCARTDCP 152
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSE--EKPLDRQPCELEP 507
P + W C CG G Q R+ VC + GR LS+ C + PL R C++
Sbjct: 153 PHLAVGDWSKCSVSCGVGIQRRKQVCQRLAAKGRRIPLSEMMCRDLPGLPLVRS-CQMPE 211
Query: 508 CEGV 511
C +
Sbjct: 212 CSKI 215
Score = 103 bits (246), Expect = 9e-21
Identities = 68/222 (30%), Positives = 101/222 (45%), Gaps = 19/222 (8%)
Query: 354 CRSREELEVVDEGLCDDGLKP-ATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR 412
C + + V++ LCD +P A +Q CNT+ CPP+W G+W CS CG G ++R+V
Sbjct: 3 CLHIQTQQTVNDSLCDMVHRPPAMSQACNTEPCPPRWHVGSWGPCSATCGV-GIQTRDVY 61
Query: 413 CEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTR 472
C + P+ +EC D KP ++CN P W I W+ C + CG G Q R
Sbjct: 62 C--LHPGETPA--PPEECRD---EKPHALQACNQFDCPPGWHIEEWQQCSRTCGGGTQNR 114
Query: 473 QVVCYQ-KNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRS 530
+V C Q +G LSD+ C K + C C V +W+ C +C ++
Sbjct: 115 RVTCRQLLTDGSFLNLSDELCQGPKASSHKSCARTDCP-PHLAVGDWSKCSVSCGVGIQR 173
Query: 531 RVAQC---VTKDYRV-VNSSFCSYHPTPALEEPCDKDKLPAC 568
R C K R+ ++ C P L C ++P C
Sbjct: 174 RKQVCQRLAAKGRRIPLSEMMCRDLPGLPLVRSC---QMPEC 212
Score = 100 bits (239), Expect = 6e-20
Identities = 81/272 (29%), Positives = 111/272 (40%), Gaps = 28/272 (10%)
Query: 325 PTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGLKP-ATNQTCNT 382
P Q W GN+S CSATCG G + + C E V E LCD KP A + CN
Sbjct: 754 PPQEPFWEPGNWSHCSATCGHLGARIQRPQCVMANGQE-VSEALCDHLQKPLAGFEPCNI 812
Query: 383 QACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL---LGPKPA 439
+ CP +W WS+CS CG +G SR+V C++ NG VV + C LG KP
Sbjct: 813 RDCPARWFTSVWSQCSVSCG-EGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPC 871
Query: 440 LYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK-PL 498
C W+P ++ C R V Q++ + SD C + K P
Sbjct: 872 FGHPC-----------VQWEPGNR-CPGRCMGRAVRMQQRHTACQHNSSDSNCDDRKRPT 919
Query: 499 DRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFCSYHPTP-- 554
R+ C C+ V W W C C +SR C+ T+ + V C P
Sbjct: 920 LRRNCTSGACD-VCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCKPVAKRHCVQKKKPIS 978
Query: 555 ---ALEEPCDKDKLPACQVQWYATQWSKCSVE 583
L CD+D + + CS++
Sbjct: 979 WRHCLGPSCDRDCTDTTHYCMFVKHLNLCSLD 1010
Score = 91.5 bits (217), Expect = 3e-17
Identities = 55/175 (31%), Positives = 75/175 (42%), Gaps = 12/175 (6%)
Query: 425 VDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRI 484
V+D C D++ PA+ ++CN + P W + W PC CG G QTR V C
Sbjct: 12 VNDSLC-DMVHRPPAMSQACNTEPCPPRWHVGSWGPCSATCGVGIQTRDVYCLHPGE--- 67
Query: 485 NVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQC--VTKDYR 541
+EC +EKP Q C C W + EW C TC ++R C + D
Sbjct: 68 TPAPPEECRDEKPHALQACNQFDCP-PGWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGS 126
Query: 542 VVN-SSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+N S P + + C + C WSKCSV CGVG + R+ C
Sbjct: 127 FLNLSDELCQGPKASSHKSCARTD---CPPHLAVGDWSKCSVSCGVGIQRRKQVC 178
Score = 77.0 bits (181), Expect = 7e-13
Identities = 51/166 (30%), Positives = 72/166 (43%), Gaps = 12/166 (7%)
Query: 497 PLDRQPCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPA 555
P Q C EPC W V W C TC +++R C+ C A
Sbjct: 24 PAMSQACNTEPCPP-RWHVGSWGPCSATCGVGIQTRDVYCLHPGETPAPPEECRDEKPHA 82
Query: 556 LEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKF--DGASVMKVDDSNCPK 613
L+ C++ C W+ +W +CS CG G + RRV C + DG S + + D C +
Sbjct: 83 LQA-CNQFD---CPPGWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDG-SFLNLSDELC-Q 136
Query: 614 EEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLR 659
K + K C + CP WS+C+ SCG G++ R VC R
Sbjct: 137 GPKASSHKSCARTD--CPPHLAVGDWSKCSVSCGVGIQRRKQVCQR 180
Score = 72.9 bits (171), Expect = 1e-11
Identities = 37/118 (31%), Positives = 60/118 (50%), Gaps = 10/118 (8%)
Query: 541 RVVNSSFCSY-HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFD 599
+ VN S C H PA+ + C+ + C +W+ W CS CGVG +TR V+C
Sbjct: 10 QTVNDSLCDMVHRPPAMSQACNTEP---CPPRWHVGSWGPCSATCGVGIQTRDVYC-LHP 65
Query: 600 GASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC 657
G + ++ C ++EK + + C + CP W+ W +C+++CG G + R V C
Sbjct: 66 GETPAPPEE--C-RDEKPHALQACN--QFDCPPGWHIEEWQQCSRTCGGGTQNRRVTC 118
Score = 72.9 bits (171), Expect = 1e-11
Identities = 67/246 (27%), Positives = 97/246 (39%), Gaps = 26/246 (10%)
Query: 451 PTWFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECSEEKPLDR-QPCELEPC 508
P W W C CG G + ++ C N ++ D +KPL +PC + C
Sbjct: 758 PFWEPGNWSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHL--QKPLAGFEPCNIRDC 815
Query: 509 EGVDWMVSEWTGCD-TCLATVRSRVAQCV-TK---DYRVVNSSFCSYHPTPALEEPCDKD 563
W S W+ C +C SR C TK +VV+ C+ P +PC
Sbjct: 816 PA-RWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGH 874
Query: 564 KLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C VQW ++C C +G+ R + A DSNC ++ + C
Sbjct: 875 P---C-VQW--EPGNRCPGRC-MGRAVRMQ---QRHTACQHNSSDSNCDDRKRPTLRRNC 924
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL--RGGKEFS--DCPKKSLPDSAGSC 679
C W+ PW CT +CG+G + R V C+ R K + C +K P S C
Sbjct: 925 T--SGACDVCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCKPVAKRHCVQKKKPISWRHC 982
Query: 680 NEQSCE 685
SC+
Sbjct: 983 LGPSCD 988
Score = 47.6 bits (108), Expect = 5e-04
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 7/83 (8%)
Query: 606 VDDSNCPKEEKYND-SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEF 664
V+DS C + S+ C E CP +W+ W C+ +CG G++ R V CL G+
Sbjct: 12 VNDSLCDMVHRPPAMSQACNT--EPCPPRWHVGSWGPCSATCGVGIQTRDVYCLHPGETP 69
Query: 665 S---DCPKKSLPDSAGSCNEQSC 684
+ +C + P + +CN+ C
Sbjct: 70 APPEEC-RDEKPHALQACNQFDC 91
>BC100788-1|AAI00789.1| 467|Homo sapiens C9orf94 protein protein.
Length = 467
Score = 119 bits (287), Expect = 1e-25
Identities = 81/257 (31%), Positives = 123/257 (47%), Gaps = 18/257 (7%)
Query: 314 EYSLPIEKAPLPTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGL 372
E + ++KA L Q Y W ++CSA+CG G+Q + C V+ C +
Sbjct: 179 EAGVLMQKASLVIQDYWWSVDRLATCSASCGNRGVQQPRLRCLLNST--EVNPAHCAGKV 236
Query: 373 KPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
+PA CN + CP +W+ +WS C++ CG G ++R V C+K+ +G+ + V + C
Sbjct: 237 RPAVQPIACNRRDCPSRWMVTSWSACTRSCG-GGVQTRRVTCQKLKASGISTPVSNDMCT 295
Query: 432 DLLGPKPALYESCNVDAACPTWFISPWKPCDKLC---GSGQQTRQVVCYQKNNGRINVLS 488
+ +P ++CN C W S W C+ C Q RQV C Q +G L
Sbjct: 296 Q-VAKRPVDTQACN-QQLCVEWAFSSWGQCNGPCIGPHLAVQHRQVFC-QTRDG--ITLP 350
Query: 489 DDECSE-EKPLDRQPCELEPCEGVDWMVSEWTGCD-TC-LATVRSRVAQCV-TKDYRVVN 544
++CS +P+ Q C E C V W VS WT C TC +SR +CV + + V
Sbjct: 351 SEQCSALPRPVSTQNCWSEAC-SVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVP 409
Query: 545 SSFCSYHPTPALEEPCD 561
CS+ P PA + C+
Sbjct: 410 EHLCSWGPRPANWQRCN 426
Score = 105 bits (251), Expect = 2e-21
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 23/217 (10%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYE-SCNVD 447
W + CS CG G + +RC + N + V+ C + +PA+ +CN
Sbjct: 196 WSVDRLATCSASCGNRGVQQPRLRC---LLNS--TEVNPAHCAGKV--RPAVQPIACN-R 247
Query: 448 AACPT-WFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSE--EKPLDRQPC 503
CP+ W ++ W C + CG G QTR+V C + K +G +S+D C++ ++P+D Q C
Sbjct: 248 RDCPSRWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQAC 307
Query: 504 ELEPCEGVDWMVSEWTGCD-TCLA---TVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP 559
+ C V+W S W C+ C+ V+ R C T+D + S CS P P +
Sbjct: 308 NQQLC--VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVSTQN 365
Query: 560 CDKDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFC 595
C + AC V W + W+ C+ CG G ++RRV C
Sbjct: 366 CWSE---ACSVHWRVSLWTLCTATCGNYGFQSRRVEC 399
Score = 90.6 bits (215), Expect = 5e-17
Identities = 57/190 (30%), Positives = 94/190 (49%), Gaps = 17/190 (8%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEV---VDEGLCDDGLK-PATNQTCNTQACP 386
W+ ++S+C+ +CGGG+Q+R VTC+ + + V +C K P Q CN Q C
Sbjct: 254 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQLC- 312
Query: 387 PQWVPGNWSRCSKRC-GKD-GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC 444
+W +W +C+ C G + R+V C+ LPS ++C L P+P ++C
Sbjct: 313 VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPS----EQCSAL--PRPVSTQNC 366
Query: 445 NVDAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQP 502
+A W +S W C CG+ G Q+R+V C + + + CS +P + Q
Sbjct: 367 WSEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNK--AVPEHLCSWGPRPANWQR 424
Query: 503 CELEPCEGVD 512
C + PCE ++
Sbjct: 425 CNITPCENME 434
Score = 60.5 bits (140), Expect = 6e-08
Identities = 61/247 (24%), Positives = 98/247 (39%), Gaps = 25/247 (10%)
Query: 453 WFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQP--CELEPCE 509
W + C CG+ G Q ++ C N+ +N C+ + QP C C
Sbjct: 196 WSVDRLATCSASCGNRGVQQPRLRCLL-NSTEVNPA---HCAGKVRPAVQPIACNRRDCP 251
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL--P 566
WMV+ W+ C +C V++R C +++ + T + P D
Sbjct: 252 S-RWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQ 310
Query: 567 ACQVQWYATQWSKCSVEC---GVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C V+W + W +C+ C + + R+VFC DG ++ S P+ ++ C
Sbjct: 311 LC-VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVS---TQNC 366
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGK-GLRFRSVVCL--RGGKEFSD--CPKKSLPDSAGS 678
E C W + W+ CT +CG G + R V C+ R K + C P +
Sbjct: 367 W--SEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQR 424
Query: 679 CNEQSCE 685
CN CE
Sbjct: 425 CNITPCE 431
>BC100790-1|AAI00791.1| 284|Homo sapiens C9orf94 protein protein.
Length = 284
Score = 119 bits (286), Expect = 1e-25
Identities = 80/252 (31%), Positives = 121/252 (48%), Gaps = 18/252 (7%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGLKPATN 377
++KA L Q Y W ++CSA+CG G+Q + C V+ C ++PA
Sbjct: 1 MQKASLVIQDYWWSVDRLATCSASCGNRGVQQPRLRCLLNST--EVNPAHCAGKVRPAVQ 58
Query: 378 Q-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP 436
CN + CP +W+ +WS C++ CG G ++R V C+K+ +G+ + V + C +
Sbjct: 59 PIACNRRDCPSRWMVTSWSACTRSCG-GGVQTRRVTCQKLKASGISTPVSNDMCTQ-VAK 116
Query: 437 KPALYESCNVDAACPTWFISPWKPCDKLC---GSGQQTRQVVCYQKNNGRINVLSDDECS 493
+P ++CN C W S W C+ C Q RQV C Q +G L ++CS
Sbjct: 117 RPVDTQACN-QQLCVEWAFSSWGQCNGPCIGPHLAVQHRQVFC-QTRDG--ITLPSEQCS 172
Query: 494 E-EKPLDRQPCELEPCEGVDWMVSEWTGCD-TC-LATVRSRVAQCV-TKDYRVVNSSFCS 549
+P+ Q C E C V W VS WT C TC +SR +CV + + V CS
Sbjct: 173 ALPRPVSTQNCWSEAC-SVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCS 231
Query: 550 YHPTPALEEPCD 561
+ P PA + C+
Sbjct: 232 WGPRPANWQRCN 243
Score = 105 bits (251), Expect = 2e-21
Identities = 68/217 (31%), Positives = 106/217 (48%), Gaps = 23/217 (10%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYE-SCNVD 447
W + CS CG G + +RC + N + V+ C + +PA+ +CN
Sbjct: 13 WSVDRLATCSASCGNRGVQQPRLRC---LLNS--TEVNPAHCAGKV--RPAVQPIACN-R 64
Query: 448 AACPT-WFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSE--EKPLDRQPC 503
CP+ W ++ W C + CG G QTR+V C + K +G +S+D C++ ++P+D Q C
Sbjct: 65 RDCPSRWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQAC 124
Query: 504 ELEPCEGVDWMVSEWTGCD-TCLA---TVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP 559
+ C V+W S W C+ C+ V+ R C T+D + S CS P P +
Sbjct: 125 NQQLC--VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVSTQN 182
Query: 560 CDKDKLPACQVQWYATQWSKCSVECG-VGKKTRRVFC 595
C + AC V W + W+ C+ CG G ++RRV C
Sbjct: 183 CWSE---ACSVHWRVSLWTLCTATCGNYGFQSRRVEC 216
Score = 90.6 bits (215), Expect = 5e-17
Identities = 57/190 (30%), Positives = 94/190 (49%), Gaps = 17/190 (8%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEV---VDEGLCDDGLK-PATNQTCNTQACP 386
W+ ++S+C+ +CGGG+Q+R VTC+ + + V +C K P Q CN Q C
Sbjct: 71 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQLC- 129
Query: 387 PQWVPGNWSRCSKRC-GKD-GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESC 444
+W +W +C+ C G + R+V C+ LPS ++C L P+P ++C
Sbjct: 130 VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPS----EQCSAL--PRPVSTQNC 183
Query: 445 NVDAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQP 502
+A W +S W C CG+ G Q+R+V C + + + CS +P + Q
Sbjct: 184 WSEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNK--AVPEHLCSWGPRPANWQR 241
Query: 503 CELEPCEGVD 512
C + PCE ++
Sbjct: 242 CNITPCENME 251
Score = 60.5 bits (140), Expect = 6e-08
Identities = 61/247 (24%), Positives = 98/247 (39%), Gaps = 25/247 (10%)
Query: 453 WFISPWKPCDKLCGS-GQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQP--CELEPCE 509
W + C CG+ G Q ++ C N+ +N C+ + QP C C
Sbjct: 13 WSVDRLATCSASCGNRGVQQPRLRCLL-NSTEVNPA---HCAGKVRPAVQPIACNRRDCP 68
Query: 510 GVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKL--P 566
WMV+ W+ C +C V++R C +++ + T + P D
Sbjct: 69 S-RWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQ 127
Query: 567 ACQVQWYATQWSKCSVEC---GVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C V+W + W +C+ C + + R+VFC DG ++ S P+ ++ C
Sbjct: 128 LC-VEWAFSSWGQCNGPCIGPHLAVQHRQVFCQTRDGITLPSEQCSALPRPVS---TQNC 183
Query: 624 EVPEEKCPSKWYAAPWSECTKSCGK-GLRFRSVVCL--RGGKEFSD--CPKKSLPDSAGS 678
E C W + W+ CT +CG G + R V C+ R K + C P +
Sbjct: 184 W--SEACSVHWRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQR 241
Query: 679 CNEQSCE 685
CN CE
Sbjct: 242 CNITPCE 248
>BC016451-1|AAH16451.1| 364|Homo sapiens ADAMTS3 protein protein.
Length = 364
Score = 118 bits (285), Expect = 2e-25
Identities = 62/183 (33%), Positives = 83/183 (45%), Gaps = 17/183 (9%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPAT-NQTCNTQACP- 386
+ W ++S CS CGGG Q CR + + ++V C+ KP + CN Q C
Sbjct: 6 FEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTH 65
Query: 387 PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV 446
P WV W C+K CG G + R VRC + + +G V K C +G +P CN
Sbjct: 66 PLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYC---MGDRPESRRPCN- 121
Query: 447 DAACPT-WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCEL 505
CP W PW C CG G + RQV+C + D C EKP + C+L
Sbjct: 122 RVPCPAQWKTGPWSECSVTCGEGTEVRQVLC----------RAGDHCDGEKPESVRACQL 171
Query: 506 EPC 508
PC
Sbjct: 172 PPC 174
Score = 83.0 bits (196), Expect = 1e-14
Identities = 51/177 (28%), Positives = 81/177 (45%), Gaps = 11/177 (6%)
Query: 453 WFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVD 512
W + W C K CG G Q + C +K++ ++ S E +++ R+ C ++ C
Sbjct: 8 WALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPL 67
Query: 513 WMVSEWTGC-DTCLAT-VRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDKLP 566
W+ EW C TC ++ + R +C+ R V+S +C P PC +++P
Sbjct: 68 WVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYC-MGDRPESRRPC--NRVP 124
Query: 567 ACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPC 623
C QW WS+CSV CG G + R+V C D K + + ND +PC
Sbjct: 125 -CPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCND-EPC 179
Score = 80.6 bits (190), Expect = 6e-14
Identities = 57/190 (30%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV- 446
+W +WS+CSK CG G + + C + N +V C PKP + CN+
Sbjct: 7 EWALKSWSQCSKPCG-GGFQYTKYGCRRKSDN---KMVHRSFCEANKKPKP-IRRMCNIQ 61
Query: 447 DAACPTWFISPWKPCDKLCGS-GQQTRQVVCYQKN-NGRINVLSDDECSEEKPLDRQPCE 504
+ P W W+ C K CGS G Q R V C Q +G + C ++P R+PC
Sbjct: 62 ECTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESRRPCN 121
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDY--RVVNSSFCSYHPTPALEEPCD 561
PC W W+ C TC R C D+ S + P +EPC
Sbjct: 122 RVPCPA-QWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCNDEPCL 180
Query: 562 KDKLPACQVQ 571
DK CQ++
Sbjct: 181 GDKSIFCQME 190
Score = 77.4 bits (182), Expect = 5e-13
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 16/193 (8%)
Query: 506 EPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTK-DYRVVNSSFCSYHPTPA-LEEPCDK 562
E + +W + W+ C C + C K D ++V+ SFC + P + C+
Sbjct: 1 EELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNI 60
Query: 563 DKLPACQVQWYATQWSKCSVECGV-GKKTRRVFCGK--FDGASVMKVDDSNCPKEEKYND 619
+ W A +W C+ CG G + R V C + DG + V C ++
Sbjct: 61 QE--CTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTN-RSVHSKYC-MGDRPES 116
Query: 620 SKPCE-VPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGS 678
+PC VP CP++W PWSEC+ +CG+G R V+C G + P+
Sbjct: 117 RRPCNRVP---CPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPP 173
Query: 679 CNEQSCEALGEGS 691
CN++ C LG+ S
Sbjct: 174 CNDEPC--LGDKS 184
>AK131039-1|BAC85480.1| 288|Homo sapiens protein ( Homo sapiens
cDNA FLJ29005 fis, clone TST07872. ).
Length = 288
Score = 118 bits (284), Expect = 2e-25
Identities = 70/219 (31%), Positives = 97/219 (44%), Gaps = 11/219 (5%)
Query: 346 GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKD 404
G+Q ++V C+ ++ +V CD KP NQ CNT+ CPP+W G+W CSK C
Sbjct: 30 GVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTC-DG 88
Query: 405 GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKL 464
G R+R V C + I +D C L +P E CN + P W W C
Sbjct: 89 GMRTRAVLCIRKIGPSEEETLDYSGC---LTHRPVEKEPCNNQSCPPQWVALDWSECTPK 145
Query: 465 CGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEGVDWMVSEWTGCDT 523
CG G + R V+C K++ +C EE KP R C L C W+ +W C
Sbjct: 146 CGPGFKHRIVLC--KSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPPPRWVTGDWGQCSA 203
Query: 524 -CLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD 561
C + R QC++ Y SS C P + C+
Sbjct: 204 QCGLGQQMRTVQCLS--YTGQASSDCLETVRPPSMQQCE 240
Score = 113 bits (273), Expect = 5e-24
Identities = 70/228 (30%), Positives = 111/228 (48%), Gaps = 21/228 (9%)
Query: 468 GQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQ-PCELEPCEGVDWMVSEWTGCD-TC 524
G Q ++VVC + ++ +++ ++ C + KP + Q C EPC +W + +W C TC
Sbjct: 30 GVQRQEVVCKRLDDN--SIVQNNYCDPDSKPPENQRACNTEPCPP-EWFIGDWLECSKTC 86
Query: 525 LATVRSRVAQCVTK----DYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKC 580
+R+R C+ K + ++ S C H P +EPC+ +C QW A WS+C
Sbjct: 87 DGGMRTRAVLCIRKIGPSEEETLDYSGCLTH-RPVEKEPCNNQ---SCPPQWVALDWSEC 142
Query: 581 SVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS-KWYAAPW 639
+ +CG G K R V C D + + CP+E K C + +CP +W W
Sbjct: 143 TPKCGPGFKHRIVLCKSSDLSKTFPA--AQCPEESKPPVRIRCSLG--RCPPPRWVTGDW 198
Query: 640 SECTKSCGKGLRFRSVVCLR-GGKEFSDCPKKSLPDSAGSCNEQSCEA 686
+C+ CG G + R+V CL G+ SDC + P S C E C++
Sbjct: 199 GQCSAQCGLGQQMRTVQCLSYTGQASSDCLETVRPPSMQQC-ESKCDS 245
Score = 104 bits (249), Expect = 4e-21
Identities = 69/261 (26%), Positives = 112/261 (42%), Gaps = 16/261 (6%)
Query: 405 GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKL 464
G + +EV C+++ N S+V + C D P +CN + P WFI W C K
Sbjct: 30 GVQRQEVVCKRLDDN---SIVQNNYC-DPDSKPPENQRACNTEPCPPEWFIGDWLECSKT 85
Query: 465 CGSGQQTRQVVCYQK-NNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCDT 523
C G +TR V+C +K L C +P++++PC + C W+ +W+ C
Sbjct: 86 CDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQSCPP-QWVALDWSECTP 144
Query: 524 -CLATVRSRVAQCVTKDY-RVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCS 581
C + R+ C + D + ++ C P + C + P +W W +CS
Sbjct: 145 KCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPP--PRWVTGDWGQCS 202
Query: 582 VECGVGKKTRRVFCGKFDGAS----VMKVDDSNCPKEEKYNDSKPCEVPEE-KCPSKWYA 636
+CG+G++ R V C + G + + V + + E DS P EE K +K
Sbjct: 203 AQCGLGQQMRTVQCLSYTGQASSDCLETVRPPSMQQCESKCDSTPISNTEECKDVNKVAY 262
Query: 637 APWSECTKSCGKGLRFRSVVC 657
P K C + FR + C
Sbjct: 263 CPLVLKFKFCSRAY-FRQMCC 282
Score = 92.7 bits (220), Expect = 1e-17
Identities = 66/212 (31%), Positives = 92/212 (43%), Gaps = 24/212 (11%)
Query: 305 IDENVGVEYEYSLPIEKAPLPTQRY--------SWVHGNFSSCSATCGGGIQSRDVTCRS 356
+D+N V+ Y P K P QR W G++ CS TC GG+++R V C
Sbjct: 41 LDDNSIVQNNYCDPDSKPP-ENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIR 99
Query: 357 R---EELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRC 413
+ E E +D C +P + CN Q+CPPQWV +WS C+ +CG G + R V C
Sbjct: 100 KIGPSEEETLDYSGCLTH-RPVEKEPCNNQSCPPQWVALDWSECTPKCG-PGFKHRIVLC 157
Query: 414 EKIITNGLPSVVDDKECFDLLGPKPALYESCNVD-AACPTWFISPWKPCDKLCGSGQQTR 472
+ ++ L +C + KP + C++ P W W C CG GQQ R
Sbjct: 158 K---SSDLSKTFPAAQCPE--ESKPPVRIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMR 212
Query: 473 QVVCYQKNNGRINVLSDDECSEEKPLDRQPCE 504
V C S D +P Q CE
Sbjct: 213 TVQCLSYT----GQASSDCLETVRPPSMQQCE 240
Score = 57.2 bits (132), Expect = 6e-07
Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 19/131 (14%)
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNC-PKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKS 645
G + + V C + D S+ V ++ C P + + + C E CP +W+ W EC+K+
Sbjct: 30 GVQRQEVVCKRLDDNSI--VQNNYCDPDSKPPENQRACNT--EPCPPEWFIGDWLECSKT 85
Query: 646 CGKGLRFRSVVCLR--GGKE-----FSDCPKKSLPDSAGSCNEQSCEALGEGSGYFTSLD 698
C G+R R+V+C+R G E +S C P CN QSC + +LD
Sbjct: 86 CDGGMRTRAVLCIRKIGPSEEETLDYSGC-LTHRPVEKEPCNNQSCPP------QWVALD 138
Query: 699 LESTFPEIGSG 709
P+ G G
Sbjct: 139 WSECTPKCGPG 149
>AJ011374-1|CAB66157.1| 364|Homo sapiens hypothetical protein
protein.
Length = 364
Score = 116 bits (279), Expect = 9e-25
Identities = 73/260 (28%), Positives = 114/260 (43%), Gaps = 21/260 (8%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQY 114
+PCSR+CGGGV +++R C P G C G D + C TQ C + L+F ++QCA+
Sbjct: 66 SPCSRSCGGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCART 125
Query: 115 NNVTFRGKK-----YRW---VPYLKVSKPCELTCMQHGDRFYYRHKEKVIDGTRC----- 161
+ R Y W VP+ + C C G+ F + + +DGTRC
Sbjct: 126 DGQPLRSSPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGP 185
Query: 162 -NDDSFDVCVDGVCQPVGCDMMLGSNAKEDKCRQCRGNGHNCHTTKKLINTQDLRKGYND 220
D + +CV G C+ GCD + S D+C+ C G+ C K R+ Y
Sbjct: 186 REDGTLSLCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRARE-YVT 244
Query: 221 ILLIPEGATTIYITEIEPSNNYLALRSKNGTYYLNGDYHID----FPRSMTIAGALWNYE 276
L + T++YI P +LA+R G Y + G I +P + +
Sbjct: 245 FLTVTPNLTSVYIANHRPLFTHLAVRI-GGRYVVAGKMSISPNTTYPSLLEDGRVEYRVA 303
Query: 277 RNQQGITAPDKLRSLGPINE 296
+ + +++R GP+ E
Sbjct: 304 LTEDRLPRLEEIRIWGPLQE 323
>AL359934-1|CAB95770.1| 432|Homo sapiens ADAMTS7, alternatively
spliced product protein.
Length = 432
Score = 111 bits (267), Expect = 3e-23
Identities = 74/243 (30%), Positives = 106/243 (43%), Gaps = 31/243 (12%)
Query: 323 PLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNT 382
PL + SW GN+S CS TCG G R V C S + + G +P + C+
Sbjct: 153 PLVVRNASWQAGNWSECSTTCGLGAVWRPVRCSSGRDEDCAPAG------RPQPARRCHL 206
Query: 383 QACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGP-KPALY 441
+ C W GNWS+CS+ CG G+ R+V+C + T L + + GP KP +
Sbjct: 207 RPC-ATWHSGNWSKCSRSCG-GGSSVRDVQC--VDTRDLRPL---RPFHCQPGPAKPPAH 259
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDR 500
C C +W+ S W+ C + CG G+Q R V C + C E +P
Sbjct: 260 RPCGAQ-PCLSWYTSSWRECSEACGGGEQQRLVTCPEPG----------LCEEALRPNTT 308
Query: 501 QPCELEPCEGVDWMVSEWTGCDT-CLATVRSRVAQCVTKDYRV--VNSSFCSYHPTPALE 557
+PC PC W+V W C C V+ R+ +CV + +S C + P
Sbjct: 309 RPCNTHPC--TQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTGLPEEDSDQCGHEAWPESS 366
Query: 558 EPC 560
PC
Sbjct: 367 RPC 369
Score = 100 bits (240), Expect = 5e-20
Identities = 70/243 (28%), Positives = 105/243 (43%), Gaps = 36/243 (14%)
Query: 452 TWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEE-KPLDRQPCELEPCEG 510
+W W C CG G R V C ++GR D++C+ +P + C L PC
Sbjct: 160 SWQAGNWSECSTTCGLGAVWRPVRC---SSGR-----DEDCAPAGRPQPARRCHLRPC-- 209
Query: 511 VDWMVSEWTGCD-TCLATVRSRVAQCV-TKDYRVVNSSFCSYHPT-PALEEPCDKDKLPA 567
W W+ C +C R QCV T+D R + C P P PC
Sbjct: 210 ATWHSGNWSKCSRSCGGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPPAHRPCGAQP--- 266
Query: 568 CQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPE 627
C + WY + W +CS CG G++ R V C + C + + N ++PC
Sbjct: 267 C-LSWYTSSWRECSEACGGGEQQRLVTCP----------EPGLCEEALRPNTTRPCNT-- 313
Query: 628 EKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRG----GKEFSD-CPKKSLPDSAGSCNEQ 682
C ++W PW +C+ CG G++ R V C+ +E SD C ++ P+S+ C +
Sbjct: 314 HPC-TQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTGLPEEDSDQCGHEAWPESSRPCGTE 372
Query: 683 SCE 685
CE
Sbjct: 373 DCE 375
Score = 100 bits (239), Expect = 6e-20
Identities = 61/185 (32%), Positives = 79/185 (42%), Gaps = 19/185 (10%)
Query: 330 SWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDG-LKPATNQTCNTQACPPQ 388
+W GN+S CS +CGGG RDV C +L + C G KP ++ C Q C
Sbjct: 211 TWHSGNWSKCSRSCGGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPPAHRPCGAQPCL-S 269
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W +W CS+ CG G + R V C + P + C + L P CN
Sbjct: 270 WYTSSWRECSEACG-GGEQQRLVTCPE------PGL-----CEEALRPNTT--RPCNTHP 315
Query: 449 ACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK-PLDRQPCELEP 507
C W + PW C CG G Q R V C G + D+C E P +PC E
Sbjct: 316 -CTQWVVGPWGQCSAPCGGGVQRRLVKCVNTQTG-LPEEDSDQCGHEAWPESSRPCGTED 373
Query: 508 CEGVD 512
CE V+
Sbjct: 374 CEPVE 378
Score = 58.0 bits (134), Expect = 3e-07
Identities = 38/127 (29%), Positives = 54/127 (42%), Gaps = 16/127 (12%)
Query: 563 DKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP 622
D L W A WS+CS CG+G R V C G D +C + ++
Sbjct: 152 DPLVVRNASWQAGNWSECSTTCGLGAVWRPVRCSS--GR------DEDCAPAGRPQPARR 203
Query: 623 CEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPDSAG 677
C + C + W++ WS+C++SCG G R V C LR + F P + P +
Sbjct: 204 CHL--RPCAT-WHSGNWSKCSRSCGGGSSVRDVQCVDTRDLRPLRPFHCQPGPAKPPAHR 260
Query: 678 SCNEQSC 684
C Q C
Sbjct: 261 PCGAQPC 267
Score = 44.4 bits (100), Expect = 0.004
Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 632 SKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+ W A WSEC+ +CG G +R V C G E DC P A C+ + C G+
Sbjct: 159 ASWQAGNWSECSTTCGLGAVWRPVRCSSGRDE--DCAPAGRPQPARRCHLRPCATWHSGN 216
>AY358142-1|AAQ88509.1| 576|Homo sapiens Bikunin hlg protein.
Length = 576
Score = 110 bits (264), Expect = 6e-23
Identities = 48/131 (36%), Positives = 68/131 (51%), Gaps = 2/131 (1%)
Query: 1582 PKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPART 1641
P C P C RW++D++ C F +G C N N+F+T E C C
Sbjct: 324 PAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPL 383
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD-PPGT 1700
CSLP +G C PRW +N +T +C+ F++GGCEGN N F S AC++ C P G
Sbjct: 384 A-ACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGN 442
Query: 1701 LQPRCSQPREQ 1711
+ R +PR++
Sbjct: 443 QRCRACKPRQK 453
Score = 101 bits (243), Expect = 2e-20
Identities = 47/121 (38%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
W++D + C F +G N N F T E C C+ P AC LP ++G C Y RW
Sbjct: 344 WHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMS-GPLAACSLPALQGPCKAYAPRW 402
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWG 1662
Y+S+ QC FVYGGC GN NNF++RE C+ C R +C R +F R
Sbjct: 403 AYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSD 462
Query: 1663 F 1663
F
Sbjct: 463 F 463
Score = 97.5 bits (232), Expect = 5e-19
Identities = 42/109 (38%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ-DVCQ 1899
C D C + +TRW +DA+ C F +G C N N+F + E C C C
Sbjct: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACS 387
Query: 1900 LPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
LP L GPC W Y++ C F YGGC GN N F SR+ CE C
Sbjct: 388 LPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
Score = 95.1 bits (226), Expect = 2e-18
Identities = 46/131 (35%), Positives = 59/131 (45%), Gaps = 3/131 (2%)
Query: 1686 GSEAACKQRCDPPGTLQP--RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQN 1743
G +AA P GT P C +P + C E W F C F + C N N
Sbjct: 307 GHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLN 366
Query: 1744 RFEDEAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENK 1803
FE AC +C + C+LPA G C Y +W Y++ +C+ F YGGC GN N
Sbjct: 367 HFETYEACMLACMSGPLA-ACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNN 425
Query: 1804 FNSQIECESRC 1814
F S+ CE C
Sbjct: 426 FESREACEESC 436
Score = 88.2 bits (209), Expect = 3e-16
Identities = 43/115 (37%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
+C P + C RW F+ + C F +G C N N F + AC C G L
Sbjct: 327 ECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC-MSGPLAA 385
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEP 1758
CS P QG C A W ++ G+C+ F Y GC GN N FE AC SCP P
Sbjct: 386 -CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFP 439
Score = 81.4 bits (192), Expect = 3e-14
Identities = 40/114 (35%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Query: 1983 ECEVSPTLERCVAPGLVWYLDAARRECVVHSNAESGLTCRNTGTFQTQEACERSCGAFKD 2042
EC P E C W+ DA C+ + G RN F+T EAC +C +
Sbjct: 327 ECLKPPDSEDCGEEQTRWHFDAQANNCLTFT---FGHCHRNLNHFETYEACMLACMS-GP 382
Query: 2043 INVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+ C P GPC+AY P++ ++++ CQ FVYGGC G N F + C E C
Sbjct: 383 LAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
Score = 79.8 bits (188), Expect = 1e-13
Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 21/152 (13%)
Query: 1744 RFEDEAACASSCPE--PFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNE 1801
R AA + S P F C P ++ +C + +W +D C F +G C N
Sbjct: 306 RGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNL 365
Query: 1802 NKFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDA 1861
N F + C C GP + C GPC + RW+Y++
Sbjct: 366 NHFETYEACMLACMS-----------------GPLAA--CSLPALQGPCKAYAPRWAYNS 406
Query: 1862 RGGRCAPFQYGGCGGNTNNFASEEHCQYYCHF 1893
+ G+C F YGGC GN NNF S E C+ C F
Sbjct: 407 QTGQCQSFVYGGCEGNGNNFESREACEESCPF 438
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/65 (38%), Positives = 36/65 (55%)
Query: 1526 ACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDA 1585
ACSL +G + Y+ W Y+ + G C F YGG +GNGN F ++E C++ C P
Sbjct: 385 ACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQR 444
Query: 1586 CKLPK 1590
C+ K
Sbjct: 445 CRACK 449
Score = 42.7 bits (96), Expect = 0.014
Identities = 19/60 (31%), Positives = 27/60 (45%)
Query: 1898 CQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRVAEVS 1957
C P + C + W +DA + C F +G C N N F + + C C SG +A S
Sbjct: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACS 387
>AF468657-1|AAL77058.1| 576|Homo sapiens multivalent protease
inhibitor protein protein.
Length = 576
Score = 110 bits (264), Expect = 6e-23
Identities = 48/131 (36%), Positives = 68/131 (51%), Gaps = 2/131 (1%)
Query: 1582 PKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPART 1641
P C P C RW++D++ C F +G C N N+F+T E C C
Sbjct: 324 PAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPL 383
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD-PPGT 1700
CSLP +G C PRW +N +T +C+ F++GGCEGN N F S AC++ C P G
Sbjct: 384 A-ACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGN 442
Query: 1701 LQPRCSQPREQ 1711
+ R +PR++
Sbjct: 443 QRCRACKPRQK 453
Score = 101 bits (243), Expect = 2e-20
Identities = 47/121 (38%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
W++D + C F +G N N F T E C C+ P AC LP ++G C Y RW
Sbjct: 344 WHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMS-GPLAACSLPALQGPCKAYAPRW 402
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWG 1662
Y+S+ QC FVYGGC GN NNF++RE C+ C R +C R +F R
Sbjct: 403 AYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSD 462
Query: 1663 F 1663
F
Sbjct: 463 F 463
Score = 97.5 bits (232), Expect = 5e-19
Identities = 42/109 (38%), Positives = 52/109 (47%), Gaps = 1/109 (0%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ-DVCQ 1899
C D C + +TRW +DA+ C F +G C N N+F + E C C C
Sbjct: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACS 387
Query: 1900 LPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
LP L GPC W Y++ C F YGGC GN N F SR+ CE C
Sbjct: 388 LPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
Score = 95.1 bits (226), Expect = 2e-18
Identities = 46/131 (35%), Positives = 59/131 (45%), Gaps = 3/131 (2%)
Query: 1686 GSEAACKQRCDPPGTLQP--RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQN 1743
G +AA P GT P C +P + C E W F C F + C N N
Sbjct: 307 GHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLN 366
Query: 1744 RFEDEAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENK 1803
FE AC +C + C+LPA G C Y +W Y++ +C+ F YGGC GN N
Sbjct: 367 HFETYEACMLACMSGPLA-ACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNN 425
Query: 1804 FNSQIECESRC 1814
F S+ CE C
Sbjct: 426 FESREACEESC 436
Score = 88.2 bits (209), Expect = 3e-16
Identities = 43/115 (37%), Positives = 53/115 (46%), Gaps = 2/115 (1%)
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
+C P + C RW F+ + C F +G C N N F + AC C G L
Sbjct: 327 ECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC-MSGPLAA 385
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEP 1758
CS P QG C A W ++ G+C+ F Y GC GN N FE AC SCP P
Sbjct: 386 -CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFP 439
Score = 81.4 bits (192), Expect = 3e-14
Identities = 40/114 (35%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Query: 1983 ECEVSPTLERCVAPGLVWYLDAARRECVVHSNAESGLTCRNTGTFQTQEACERSCGAFKD 2042
EC P E C W+ DA C+ + G RN F+T EAC +C +
Sbjct: 327 ECLKPPDSEDCGEEQTRWHFDAQANNCLTFT---FGHCHRNLNHFETYEACMLACMS-GP 382
Query: 2043 INVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+ C P GPC+AY P++ ++++ CQ FVYGGC G N F + C E C
Sbjct: 383 LAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436
Score = 79.8 bits (188), Expect = 1e-13
Identities = 46/152 (30%), Positives = 63/152 (41%), Gaps = 21/152 (13%)
Query: 1744 RFEDEAACASSCPE--PFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNE 1801
R AA + S P F C P ++ +C + +W +D C F +G C N
Sbjct: 306 RGHQAAATSESSPNGTAFPAAECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNL 365
Query: 1802 NKFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDA 1861
N F + C C GP + C GPC + RW+Y++
Sbjct: 366 NHFETYEACMLACMS-----------------GPLAA--CSLPALQGPCKAYAPRWAYNS 406
Query: 1862 RGGRCAPFQYGGCGGNTNNFASEEHCQYYCHF 1893
+ G+C F YGGC GN NNF S E C+ C F
Sbjct: 407 QTGQCQSFVYGGCEGNGNNFESREACEESCPF 438
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/65 (38%), Positives = 36/65 (55%)
Query: 1526 ACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDA 1585
ACSL +G + Y+ W Y+ + G C F YGG +GNGN F ++E C++ C P
Sbjct: 385 ACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQR 444
Query: 1586 CKLPK 1590
C+ K
Sbjct: 445 CRACK 449
Score = 42.7 bits (96), Expect = 0.014
Identities = 19/60 (31%), Positives = 27/60 (45%)
Query: 1898 CQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRVAEVS 1957
C P + C + W +DA + C F +G C N N F + + C C SG +A S
Sbjct: 328 CLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACS 387
>X54818-1|CAA38587.1| 151|Homo sapiens bikunin protein.
Length = 151
Score = 109 bits (263), Expect = 8e-23
Identities = 48/117 (41%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D+C+L G C+G R++Y+ C F YGGC+GN NNF T + C C RT
Sbjct: 27 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC---RTV 83
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG 1699
C+LPI RG C W F+ +C F +GGC+GN N+F SE C++ C PG
Sbjct: 84 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPG 140
Score = 105 bits (252), Expect = 2e-21
Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ + C GPC +R+ Y+ C FQYGGC GN NNF +E+ C C T
Sbjct: 25 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR-TV 83
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C LP++ GPC I W +DA + C F YGGC GN N+F S EC C
Sbjct: 84 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 136
Score = 91.1 bits (216), Expect = 4e-17
Identities = 43/122 (35%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD 1696
E + +D C L G C G R+ +N + CE F +GGC GN N F +E C Q C
Sbjct: 22 EVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 81
Query: 1697 PPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCP 1756
C+ P +G C +W F +G+C F Y GC GN N+F E C C
Sbjct: 82 TVAA----CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCG 137
Query: 1757 EP 1758
P
Sbjct: 138 VP 139
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 1523 KQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
K+ +C L G + ++Y+ C F YGG GNGN F T++EC C +
Sbjct: 26 KEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA- 84
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
AC LP V+G C + W +D+ + +C F YGGC GN N F + + C+ C
Sbjct: 85 --ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 136
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C L G C ++FY+ + C F YGGC GN N F ++ EC C +
Sbjct: 28 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA-- 85
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
C GPC F W++DA G+C F YGGC GN N F
Sbjct: 86 -------------------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKF 126
Query: 1882 ASEEHCQYYC 1891
SE+ C+ YC
Sbjct: 127 YSEKECREYC 136
Score = 78.6 bits (185), Expect = 2e-13
Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLC 1764
C G C + ++++ C F Y GC GN N F E C +C C
Sbjct: 30 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---C 86
Query: 1765 TLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
LP G C + + W +D + +C F YGGC GN NKF S+ EC C
Sbjct: 87 NLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 136
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2023 NTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGG 2082
N F T++ C ++C + + C P+ GPCRA++ + FD + C F YGGC G
Sbjct: 66 NGNNFVTEKECLQTC---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN 122
Query: 2083 PNRFSTIAECTEVC 2096
N+F + EC E C
Sbjct: 123 GNKFYSEKECREYC 136
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
+D CQL AGPC +FY+ + AC F YGGC GN N F + EC CR+
Sbjct: 27 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT 82
Score = 54.0 bits (124), Expect = 6e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1493 CSTSKYG-CCPDGQT-LAEGPKFFGCTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYG 1550
C T +YG C +G + E C + AC+L RG R + W +D G
Sbjct: 55 CETFQYGGCMGNGNNFVTEKECLQTCRTV-----AACNLPIVRGPCRAFIQLWAFDAVKG 109
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
C F YGG GNGN+F +++EC + C P D
Sbjct: 110 KCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGD 143
Score = 50.4 bits (115), Expect = 7e-05
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
C GPC +Y+++ +C+ F YGGC G N F T EC + C+
Sbjct: 30 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 81
>X54816-1|CAA38585.1| 352|Homo sapiens bikunin protein.
Length = 352
Score = 109 bits (263), Expect = 8e-23
Identities = 48/117 (41%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D+C+L G C+G R++Y+ C F YGGC+GN NNF T + C C RT
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC---RTV 284
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG 1699
C+LPI RG C W F+ +C F +GGC+GN N+F SE C++ C PG
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPG 341
Score = 105 bits (252), Expect = 2e-21
Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ + C GPC +R+ Y+ C FQYGGC GN NNF +E+ C C T
Sbjct: 226 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR-TV 284
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C LP++ GPC I W +DA + C F YGGC GN N+F S EC C
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 91.1 bits (216), Expect = 4e-17
Identities = 43/122 (35%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD 1696
E + +D C L G C G R+ +N + CE F +GGC GN N F +E C Q C
Sbjct: 223 EVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
Query: 1697 PPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCP 1756
C+ P +G C +W F +G+C F Y GC GN N+F E C C
Sbjct: 283 TVAA----CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCG 338
Query: 1757 EP 1758
P
Sbjct: 339 VP 340
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 1523 KQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
K+ +C L G + ++Y+ C F YGG GNGN F T++EC C +
Sbjct: 227 KEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA- 285
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
AC LP V+G C + W +D+ + +C F YGGC GN N F + + C+ C
Sbjct: 286 --ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C L G C ++FY+ + C F YGGC GN N F ++ EC C +
Sbjct: 229 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA-- 286
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
C GPC F W++DA G+C F YGGC GN N F
Sbjct: 287 -------------------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKF 327
Query: 1882 ASEEHCQYYC 1891
SE+ C+ YC
Sbjct: 328 YSEKECREYC 337
Score = 78.6 bits (185), Expect = 2e-13
Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLC 1764
C G C + ++++ C F Y GC GN N F E C +C C
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---C 287
Query: 1765 TLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
LP G C + + W +D + +C F YGGC GN NKF S+ EC C
Sbjct: 288 NLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2023 NTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGG 2082
N F T++ C ++C + + C P+ GPCRA++ + FD + C F YGGC G
Sbjct: 267 NGNNFVTEKECLQTC---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN 323
Query: 2083 PNRFSTIAECTEVC 2096
N+F + EC E C
Sbjct: 324 GNKFYSEKECREYC 337
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
+D CQL AGPC +FY+ + AC F YGGC GN N F + EC CR+
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT 283
Score = 54.0 bits (124), Expect = 6e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1493 CSTSKYG-CCPDGQT-LAEGPKFFGCTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYG 1550
C T +YG C +G + E C + AC+L RG R + W +D G
Sbjct: 256 CETFQYGGCMGNGNNFVTEKECLQTCRTV-----AACNLPIVRGPCRAFIQLWAFDAVKG 310
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
C F YGG GNGN+F +++EC + C P D
Sbjct: 311 KCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGD 344
Score = 50.4 bits (115), Expect = 7e-05
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
C GPC +Y+++ +C+ F YGGC G N F T EC + C+
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
>X04494-1|CAA28182.1| 352|Homo sapiens protein ( Human mRNA for
alpha-1-microglobulin and HI-30. ).
Length = 352
Score = 109 bits (263), Expect = 8e-23
Identities = 48/117 (41%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D+C+L G C+G R++Y+ C F YGGC+GN NNF T + C C RT
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC---RTV 284
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG 1699
C+LPI RG C W F+ +C F +GGC+GN N+F SE C++ C PG
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPG 341
Score = 105 bits (252), Expect = 2e-21
Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ + C GPC +R+ Y+ C FQYGGC GN NNF +E+ C C T
Sbjct: 226 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR-TV 284
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C LP++ GPC I W +DA + C F YGGC GN N+F S EC C
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 91.1 bits (216), Expect = 4e-17
Identities = 43/122 (35%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD 1696
E + +D C L G C G R+ +N + CE F +GGC GN N F +E C Q C
Sbjct: 223 EVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
Query: 1697 PPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCP 1756
C+ P +G C +W F +G+C F Y GC GN N+F E C C
Sbjct: 283 TVAA----CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCG 338
Query: 1757 EP 1758
P
Sbjct: 339 VP 340
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 1523 KQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
K+ +C L G + ++Y+ C F YGG GNGN F T++EC C +
Sbjct: 227 KEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA- 285
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
AC LP V+G C + W +D+ + +C F YGGC GN N F + + C+ C
Sbjct: 286 --ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C L G C ++FY+ + C F YGGC GN N F ++ EC C +
Sbjct: 229 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA-- 286
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
C GPC F W++DA G+C F YGGC GN N F
Sbjct: 287 -------------------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKF 327
Query: 1882 ASEEHCQYYC 1891
SE+ C+ YC
Sbjct: 328 YSEKECREYC 337
Score = 78.6 bits (185), Expect = 2e-13
Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLC 1764
C G C + ++++ C F Y GC GN N F E C +C C
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---C 287
Query: 1765 TLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
LP G C + + W +D + +C F YGGC GN NKF S+ EC C
Sbjct: 288 NLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2023 NTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGG 2082
N F T++ C ++C + + C P+ GPCRA++ + FD + C F YGGC G
Sbjct: 267 NGNNFVTEKECLQTC---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN 323
Query: 2083 PNRFSTIAECTEVC 2096
N+F + EC E C
Sbjct: 324 GNKFYSEKECREYC 337
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
+D CQL AGPC +FY+ + AC F YGGC GN N F + EC CR+
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT 283
Score = 54.0 bits (124), Expect = 6e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1493 CSTSKYG-CCPDGQT-LAEGPKFFGCTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYG 1550
C T +YG C +G + E C + AC+L RG R + W +D G
Sbjct: 256 CETFQYGGCMGNGNNFVTEKECLQTCRTV-----AACNLPIVRGPCRAFIQLWAFDAVKG 310
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
C F YGG GNGN+F +++EC + C P D
Sbjct: 311 KCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGD 344
Score = 50.4 bits (115), Expect = 7e-05
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
C GPC +Y+++ +C+ F YGGC G N F T EC + C+
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
>X04225-1|CAA27803.1| 352|Homo sapiens HC polypeptide protein.
Length = 352
Score = 109 bits (263), Expect = 8e-23
Identities = 48/117 (41%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D+C+L G C+G R++Y+ C F YGGC+GN NNF T + C C RT
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC---RTV 284
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG 1699
C+LPI RG C W F+ +C F +GGC+GN N+F SE C++ C PG
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPG 341
Score = 105 bits (252), Expect = 2e-21
Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ + C GPC +R+ Y+ C FQYGGC GN NNF +E+ C C T
Sbjct: 226 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR-TV 284
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C LP++ GPC I W +DA + C F YGGC GN N+F S EC C
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 91.1 bits (216), Expect = 4e-17
Identities = 43/122 (35%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD 1696
E + +D C L G C G R+ +N + CE F +GGC GN N F +E C Q C
Sbjct: 223 EVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
Query: 1697 PPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCP 1756
C+ P +G C +W F +G+C F Y GC GN N+F E C C
Sbjct: 283 TVAA----CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCG 338
Query: 1757 EP 1758
P
Sbjct: 339 VP 340
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 1523 KQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
K+ +C L G + ++Y+ C F YGG GNGN F T++EC C +
Sbjct: 227 KEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA- 285
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
AC LP V+G C + W +D+ + +C F YGGC GN N F + + C+ C
Sbjct: 286 --ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C L G C ++FY+ + C F YGGC GN N F ++ EC C +
Sbjct: 229 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA-- 286
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
C GPC F W++DA G+C F YGGC GN N F
Sbjct: 287 -------------------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKF 327
Query: 1882 ASEEHCQYYC 1891
SE+ C+ YC
Sbjct: 328 YSEKECREYC 337
Score = 78.6 bits (185), Expect = 2e-13
Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLC 1764
C G C + ++++ C F Y GC GN N F E C +C C
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---C 287
Query: 1765 TLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
LP G C + + W +D + +C F YGGC GN NKF S+ EC C
Sbjct: 288 NLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2023 NTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGG 2082
N F T++ C ++C + + C P+ GPCRA++ + FD + C F YGGC G
Sbjct: 267 NGNNFVTEKECLQTC---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN 323
Query: 2083 PNRFSTIAECTEVC 2096
N+F + EC E C
Sbjct: 324 GNKFYSEKECREYC 337
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
+D CQL AGPC +FY+ + AC F YGGC GN N F + EC CR+
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT 283
Score = 54.0 bits (124), Expect = 6e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1493 CSTSKYG-CCPDGQT-LAEGPKFFGCTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYG 1550
C T +YG C +G + E C + AC+L RG R + W +D G
Sbjct: 256 CETFQYGGCMGNGNNFVTEKECLQTCRTV-----AACNLPIVRGPCRAFIQLWAFDAVKG 310
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
C F YGG GNGN+F +++EC + C P D
Sbjct: 311 KCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGD 344
Score = 50.4 bits (115), Expect = 7e-05
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
C GPC +Y+++ +C+ F YGGC G N F T EC + C+
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
>M88249-1|AAA59196.1| 352|Homo sapiens inter-alpha-trypsin inhibitor
light chain protein.
Length = 352
Score = 109 bits (263), Expect = 8e-23
Identities = 48/117 (41%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D+C+L G C+G R++Y+ C F YGGC+GN NNF T + C C RT
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC---RTV 284
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG 1699
C+LPI RG C W F+ +C F +GGC+GN N+F SE C++ C PG
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPG 341
Score = 105 bits (252), Expect = 2e-21
Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ + C GPC +R+ Y+ C FQYGGC GN NNF +E+ C C T
Sbjct: 226 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR-TV 284
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C LP++ GPC I W +DA + C F YGGC GN N+F S EC C
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 91.1 bits (216), Expect = 4e-17
Identities = 43/122 (35%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD 1696
E + +D C L G C G R+ +N + CE F +GGC GN N F +E C Q C
Sbjct: 223 EVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
Query: 1697 PPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCP 1756
C+ P +G C +W F +G+C F Y GC GN N+F E C C
Sbjct: 283 TVAA----CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCG 338
Query: 1757 EP 1758
P
Sbjct: 339 VP 340
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 1523 KQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
K+ +C L G + ++Y+ C F YGG GNGN F T++EC C +
Sbjct: 227 KEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA- 285
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
AC LP V+G C + W +D+ + +C F YGGC GN N F + + C+ C
Sbjct: 286 --ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C L G C ++FY+ + C F YGGC GN N F ++ EC C +
Sbjct: 229 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA-- 286
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
C GPC F W++DA G+C F YGGC GN N F
Sbjct: 287 -------------------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKF 327
Query: 1882 ASEEHCQYYC 1891
SE+ C+ YC
Sbjct: 328 YSEKECREYC 337
Score = 78.6 bits (185), Expect = 2e-13
Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLC 1764
C G C + ++++ C F Y GC GN N F E C +C C
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---C 287
Query: 1765 TLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
LP G C + + W +D + +C F YGGC GN NKF S+ EC C
Sbjct: 288 NLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2023 NTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGG 2082
N F T++ C ++C + + C P+ GPCRA++ + FD + C F YGGC G
Sbjct: 267 NGNNFVTEKECLQTC---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN 323
Query: 2083 PNRFSTIAECTEVC 2096
N+F + EC E C
Sbjct: 324 GNKFYSEKECREYC 337
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
+D CQL AGPC +FY+ + AC F YGGC GN N F + EC CR+
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT 283
Score = 54.0 bits (124), Expect = 6e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1493 CSTSKYG-CCPDGQT-LAEGPKFFGCTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYG 1550
C T +YG C +G + E C + AC+L RG R + W +D G
Sbjct: 256 CETFQYGGCMGNGNNFVTEKECLQTCRTV-----AACNLPIVRGPCRAFIQLWAFDAVKG 310
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
C F YGG GNGN+F +++EC + C P D
Sbjct: 311 KCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGD 344
Score = 50.4 bits (115), Expect = 7e-05
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
C GPC +Y+++ +C+ F YGGC G N F T EC + C+
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
>BC041593-1|AAH41593.1| 352|Homo sapiens
alpha-1-microglobulin/bikunin precursor protein.
Length = 352
Score = 109 bits (263), Expect = 8e-23
Identities = 48/117 (41%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D+C+L G C+G R++Y+ C F YGGC+GN NNF T + C C RT
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC---RTV 284
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG 1699
C+LPI RG C W F+ +C F +GGC+GN N+F SE C++ C PG
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPG 341
Score = 105 bits (252), Expect = 2e-21
Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ + C GPC +R+ Y+ C FQYGGC GN NNF +E+ C C T
Sbjct: 226 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR-TV 284
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C LP++ GPC I W +DA + C F YGGC GN N+F S EC C
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 91.1 bits (216), Expect = 4e-17
Identities = 43/122 (35%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD 1696
E + +D C L G C G R+ +N + CE F +GGC GN N F +E C Q C
Sbjct: 223 EVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
Query: 1697 PPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCP 1756
C+ P +G C +W F +G+C F Y GC GN N+F E C C
Sbjct: 283 TVAA----CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCG 338
Query: 1757 EP 1758
P
Sbjct: 339 VP 340
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 1523 KQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
K+ +C L G + ++Y+ C F YGG GNGN F T++EC C +
Sbjct: 227 KEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA- 285
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
AC LP V+G C + W +D+ + +C F YGGC GN N F + + C+ C
Sbjct: 286 --ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C L G C ++FY+ + C F YGGC GN N F ++ EC C +
Sbjct: 229 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA-- 286
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
C GPC F W++DA G+C F YGGC GN N F
Sbjct: 287 -------------------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKF 327
Query: 1882 ASEEHCQYYC 1891
SE+ C+ YC
Sbjct: 328 YSEKECREYC 337
Score = 78.6 bits (185), Expect = 2e-13
Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLC 1764
C G C + ++++ C F Y GC GN N F E C +C C
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---C 287
Query: 1765 TLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
LP G C + + W +D + +C F YGGC GN NKF S+ EC C
Sbjct: 288 NLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2023 NTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGG 2082
N F T++ C ++C + + C P+ GPCRA++ + FD + C F YGGC G
Sbjct: 267 NGNNFVTEKECLQTC---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN 323
Query: 2083 PNRFSTIAECTEVC 2096
N+F + EC E C
Sbjct: 324 GNKFYSEKECREYC 337
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
+D CQL AGPC +FY+ + AC F YGGC GN N F + EC CR+
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT 283
Score = 54.0 bits (124), Expect = 6e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1493 CSTSKYG-CCPDGQT-LAEGPKFFGCTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYG 1550
C T +YG C +G + E C + AC+L RG R + W +D G
Sbjct: 256 CETFQYGGCMGNGNNFVTEKECLQTCRTV-----AACNLPIVRGPCRAFIQLWAFDAVKG 310
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
C F YGG GNGN+F +++EC + C P D
Sbjct: 311 KCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGD 344
Score = 50.4 bits (115), Expect = 7e-05
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
C GPC +Y+++ +C+ F YGGC G N F T EC + C+
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
>AY544123-1|AAT11154.1| 352|Homo sapiens growth-inhibiting protein 19
protein.
Length = 352
Score = 109 bits (263), Expect = 8e-23
Identities = 48/117 (41%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D+C+L G C+G R++Y+ C F YGGC+GN NNF T + C C RT
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC---RTV 284
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG 1699
C+LPI RG C W F+ +C F +GGC+GN N+F SE C++ C PG
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPG 341
Score = 105 bits (252), Expect = 2e-21
Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ + C GPC +R+ Y+ C FQYGGC GN NNF +E+ C C T
Sbjct: 226 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR-TV 284
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C LP++ GPC I W +DA + C F YGGC GN N+F S EC C
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 91.1 bits (216), Expect = 4e-17
Identities = 43/122 (35%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD 1696
E + +D C L G C G R+ +N + CE F +GGC GN N F +E C Q C
Sbjct: 223 EVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
Query: 1697 PPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCP 1756
C+ P +G C +W F +G+C F Y GC GN N+F E C C
Sbjct: 283 TVAA----CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCG 338
Query: 1757 EP 1758
P
Sbjct: 339 VP 340
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 1523 KQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
K+ +C L G + ++Y+ C F YGG GNGN F T++EC C +
Sbjct: 227 KEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA- 285
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
AC LP V+G C + W +D+ + +C F YGGC GN N F + + C+ C
Sbjct: 286 --ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C L G C ++FY+ + C F YGGC GN N F ++ EC C +
Sbjct: 229 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA-- 286
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
C GPC F W++DA G+C F YGGC GN N F
Sbjct: 287 -------------------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKF 327
Query: 1882 ASEEHCQYYC 1891
SE+ C+ YC
Sbjct: 328 YSEKECREYC 337
Score = 78.6 bits (185), Expect = 2e-13
Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLC 1764
C G C + ++++ C F Y GC GN N F E C +C C
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---C 287
Query: 1765 TLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
LP G C + + W +D + +C F YGGC GN NKF S+ EC C
Sbjct: 288 NLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2023 NTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGG 2082
N F T++ C ++C + + C P+ GPCRA++ + FD + C F YGGC G
Sbjct: 267 NGNNFVTEKECLQTC---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN 323
Query: 2083 PNRFSTIAECTEVC 2096
N+F + EC E C
Sbjct: 324 GNKFYSEKECREYC 337
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
+D CQL AGPC +FY+ + AC F YGGC GN N F + EC CR+
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT 283
Score = 54.0 bits (124), Expect = 6e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1493 CSTSKYG-CCPDGQT-LAEGPKFFGCTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYG 1550
C T +YG C +G + E C + AC+L RG R + W +D G
Sbjct: 256 CETFQYGGCMGNGNNFVTEKECLQTCRTV-----AACNLPIVRGPCRAFIQLWAFDAVKG 310
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
C F YGG GNGN+F +++EC + C P D
Sbjct: 311 KCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGD 344
Score = 50.4 bits (115), Expect = 7e-05
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
C GPC +Y+++ +C+ F YGGC G N F T EC + C+
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
>AL137850-4|CAI15899.1| 352|Homo sapiens
alpha-1-microglobulin/bikunin precursor protein.
Length = 352
Score = 109 bits (263), Expect = 8e-23
Identities = 48/117 (41%), Positives = 65/117 (55%), Gaps = 3/117 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D+C+L G C+G R++Y+ C F YGGC+GN NNF T + C C RT
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTC---RTV 284
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG 1699
C+LPI RG C W F+ +C F +GGC+GN N+F SE C++ C PG
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPG 341
Score = 105 bits (252), Expect = 2e-21
Identities = 46/113 (40%), Positives = 58/113 (51%), Gaps = 1/113 (0%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ + C GPC +R+ Y+ C FQYGGC GN NNF +E+ C C T
Sbjct: 226 KKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR-TV 284
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C LP++ GPC I W +DA + C F YGGC GN N+F S EC C
Sbjct: 285 AACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 91.1 bits (216), Expect = 4e-17
Identities = 43/122 (35%), Positives = 56/122 (45%), Gaps = 4/122 (3%)
Query: 1637 EPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCD 1696
E + +D C L G C G R+ +N + CE F +GGC GN N F +E C Q C
Sbjct: 223 EVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
Query: 1697 PPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCP 1756
C+ P +G C +W F +G+C F Y GC GN N+F E C C
Sbjct: 283 TVAA----CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCG 338
Query: 1757 EP 1758
P
Sbjct: 339 VP 340
Score = 85.8 bits (203), Expect = 1e-15
Identities = 40/114 (35%), Positives = 58/114 (50%), Gaps = 3/114 (2%)
Query: 1523 KQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
K+ +C L G + ++Y+ C F YGG GNGN F T++EC C +
Sbjct: 227 KEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA- 285
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
AC LP V+G C + W +D+ + +C F YGGC GN N F + + C+ C
Sbjct: 286 --ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 85.0 bits (201), Expect = 3e-15
Identities = 44/130 (33%), Positives = 56/130 (43%), Gaps = 21/130 (16%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C L G C ++FY+ + C F YGGC GN N F ++ EC C +
Sbjct: 229 DSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA-- 286
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
C GPC F W++DA G+C F YGGC GN N F
Sbjct: 287 -------------------CNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKF 327
Query: 1882 ASEEHCQYYC 1891
SE+ C+ YC
Sbjct: 328 YSEKECREYC 337
Score = 78.6 bits (185), Expect = 2e-13
Identities = 37/110 (33%), Positives = 49/110 (44%), Gaps = 3/110 (2%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLC 1764
C G C + ++++ C F Y GC GN N F E C +C C
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAA---C 287
Query: 1765 TLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
LP G C + + W +D + +C F YGGC GN NKF S+ EC C
Sbjct: 288 NLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337
Score = 62.1 bits (144), Expect = 2e-08
Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 3/74 (4%)
Query: 2023 NTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGG 2082
N F T++ C ++C + + C P+ GPCRA++ + FD + C F YGGC G
Sbjct: 267 NGNNFVTEKECLQTC---RTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN 323
Query: 2083 PNRFSTIAECTEVC 2096
N+F + EC E C
Sbjct: 324 GNKFYSEKECREYC 337
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
+D CQL AGPC +FY+ + AC F YGGC GN N F + EC CR+
Sbjct: 228 EDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRT 283
Score = 54.0 bits (124), Expect = 6e-06
Identities = 32/94 (34%), Positives = 44/94 (46%), Gaps = 7/94 (7%)
Query: 1493 CSTSKYG-CCPDGQT-LAEGPKFFGCTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYG 1550
C T +YG C +G + E C + AC+L RG R + W +D G
Sbjct: 256 CETFQYGGCMGNGNNFVTEKECLQTCRTV-----AACNLPIVRGPCRAFIQLWAFDAVKG 310
Query: 1551 GCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
C F YGG GNGN+F +++EC + C P D
Sbjct: 311 KCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGD 344
Score = 50.4 bits (115), Expect = 7e-05
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
C GPC +Y+++ +C+ F YGGC G N F T EC + C+
Sbjct: 231 CQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCR 282
>Z84479-2|CAM26437.1| 548|Homo sapiens WAP, follistatin/kazal,
immunoglobulin, kunitz and netrin domain containing 1
protein.
Length = 548
Score = 108 bits (259), Expect = 2e-22
Identities = 49/108 (45%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 1534 GSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKG 1593
G + V W+YD + GGC F G DG F T E C C + P DAC LP V+G
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR-GPGDACVLPAVQG 366
Query: 1594 ACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPART 1641
C G+ RW Y +QC FVYGGC GN NNF +RE C+ C RT
Sbjct: 367 PCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRT 414
Score = 101 bits (242), Expect = 3e-20
Identities = 53/130 (40%), Positives = 68/130 (52%), Gaps = 10/130 (7%)
Query: 1580 PSPKDACKLPKVKGACVG----YNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQ 1635
P+P + LP V+ AC G + V W+YD +R C F GC G A F+T E CQ
Sbjct: 294 PAPAEC--LPDVQ-ACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQA 350
Query: 1636 CEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
C D C LP +G C G PRW ++ Q+C F++GGCEGN N F S +C+ C
Sbjct: 351 CARG-PGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Query: 1696 DPPGTLQPRC 1705
P T P C
Sbjct: 410 PVPRT--PPC 417
Score = 86.6 bits (205), Expect = 8e-16
Identities = 40/102 (39%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 1848 GPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-HFTQDVCQLPMLAGP 1906
GP + W YD + G C F GC G F + E CQ C D C LP + GP
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQGP 367
Query: 1907 CNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C W Y C F YGGC GN N F SR+ CE C
Sbjct: 368 CRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 85.0 bits (201), Expect = 3e-15
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLCTLPAETGECANYEEK 1779
+W + P G C F GC G FE AC +C D C LPA G C +E +
Sbjct: 316 LWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG-PGDACVLPAVQGPCRGWEPR 374
Query: 1780 WFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
W Y ++C F YGGC GN N F+S+ CE C
Sbjct: 375 WAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 74.5 bits (175), Expect = 4e-12
Identities = 36/102 (35%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Query: 1661 WGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP-PGTLQPRCSQPREQGGCNETAA 1719
W ++ + C F GC+G + F + AC+Q C PG C P QG C
Sbjct: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDA---CVLPAVQGPCRGWEP 373
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
W +SP +C PF Y GC GN N F +C +CP P P
Sbjct: 374 RWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTP 415
Score = 70.1 bits (164), Expect = 8e-11
Identities = 45/144 (31%), Positives = 60/144 (41%), Gaps = 22/144 (15%)
Query: 1748 EAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQ 1807
+AA + P +PD+ A TG + + W YD C F GC G F +
Sbjct: 288 DAAPSIPAPAECLPDV---QACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETY 344
Query: 1808 IECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCA 1867
C+ C+ GP ++ C GPC +E RW+Y +C
Sbjct: 345 EACQQACAR-----------------GPGDA--CVLPAVQGPCRGWEPRWAYSPLLQQCH 385
Query: 1868 PFQYGGCGGNTNNFASEEHCQYYC 1891
PF YGGC GN NNF S E C+ C
Sbjct: 386 PFVYGGCEGNGNNFHSRESCEDAC 409
Score = 68.5 bits (160), Expect = 2e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 1985 EVSPTLERCVAPG----LVWYLDAARRECVVHSNAESGLTCRNTGTFQTQEACERSCGAF 2040
E P ++ C P ++W+ D R C+ R F+T EAC+++C
Sbjct: 298 ECLPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARG---FETYEACQQACARG 354
Query: 2041 KDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+ C+ P GPCR + P++ + + C FVYGGC G N F + C + C
Sbjct: 355 PG-DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 53.2 bits (122), Expect = 1e-05
Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1526 ACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQP--SPK 1583
AC L +G R + W Y C F YGG +GNGN F ++E C+D C P P
Sbjct: 358 ACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPC 417
Query: 1584 DACKL 1588
AC+L
Sbjct: 418 RACRL 422
Score = 40.7 bits (91), Expect = 0.055
Identities = 16/47 (34%), Positives = 21/47 (44%)
Query: 1905 GPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSG 1951
GP + +V W YD R C F GC G F + + C+ C G
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG 354
>BC101606-1|AAI01607.1| 548|Homo sapiens WAP, follistatin/kazal,
immunoglobulin, kunitz and netrin domain containing 1
protein.
Length = 548
Score = 108 bits (259), Expect = 2e-22
Identities = 49/108 (45%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 1534 GSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKG 1593
G + V W+YD + GGC F G DG F T E C C + P DAC LP V+G
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR-GPGDACVLPAVQG 366
Query: 1594 ACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPART 1641
C G+ RW Y +QC FVYGGC GN NNF +RE C+ C RT
Sbjct: 367 PCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRT 414
Score = 101 bits (242), Expect = 3e-20
Identities = 53/130 (40%), Positives = 68/130 (52%), Gaps = 10/130 (7%)
Query: 1580 PSPKDACKLPKVKGACVG----YNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQ 1635
P+P + LP V+ AC G + V W+YD +R C F GC G A F+T E CQ
Sbjct: 294 PAPAEC--LPDVQ-ACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQA 350
Query: 1636 CEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
C D C LP +G C G PRW ++ Q+C F++GGCEGN N F S +C+ C
Sbjct: 351 CARG-PGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Query: 1696 DPPGTLQPRC 1705
P T P C
Sbjct: 410 PVPRT--PPC 417
Score = 86.6 bits (205), Expect = 8e-16
Identities = 40/102 (39%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 1848 GPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-HFTQDVCQLPMLAGP 1906
GP + W YD + G C F GC G F + E CQ C D C LP + GP
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQGP 367
Query: 1907 CNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C W Y C F YGGC GN N F SR+ CE C
Sbjct: 368 CRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 85.0 bits (201), Expect = 3e-15
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLCTLPAETGECANYEEK 1779
+W + P G C F GC G FE AC +C D C LPA G C +E +
Sbjct: 316 LWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG-PGDACVLPAVQGPCRGWEPR 374
Query: 1780 WFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
W Y ++C F YGGC GN N F+S+ CE C
Sbjct: 375 WAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 74.5 bits (175), Expect = 4e-12
Identities = 36/102 (35%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Query: 1661 WGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP-PGTLQPRCSQPREQGGCNETAA 1719
W ++ + C F GC+G + F + AC+Q C PG C P QG C
Sbjct: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDA---CVLPAVQGPCRGWEP 373
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
W +SP +C PF Y GC GN N F +C +CP P P
Sbjct: 374 RWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTP 415
Score = 70.1 bits (164), Expect = 8e-11
Identities = 45/144 (31%), Positives = 60/144 (41%), Gaps = 22/144 (15%)
Query: 1748 EAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQ 1807
+AA + P +PD+ A TG + + W YD C F GC G F +
Sbjct: 288 DAAPSIPAPAECLPDV---QACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETY 344
Query: 1808 IECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCA 1867
C+ C+ GP ++ C GPC +E RW+Y +C
Sbjct: 345 EACQQACAR-----------------GPGDA--CVLPAVQGPCRGWEPRWAYSPLLQQCH 385
Query: 1868 PFQYGGCGGNTNNFASEEHCQYYC 1891
PF YGGC GN NNF S E C+ C
Sbjct: 386 PFVYGGCEGNGNNFHSRESCEDAC 409
Score = 68.5 bits (160), Expect = 2e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 1985 EVSPTLERCVAPG----LVWYLDAARRECVVHSNAESGLTCRNTGTFQTQEACERSCGAF 2040
E P ++ C P ++W+ D R C+ R F+T EAC+++C
Sbjct: 298 ECLPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARG---FETYEACQQACARG 354
Query: 2041 KDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+ C+ P GPCR + P++ + + C FVYGGC G N F + C + C
Sbjct: 355 PG-DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 53.2 bits (122), Expect = 1e-05
Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1526 ACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQP--SPK 1583
AC L +G R + W Y C F YGG +GNGN F ++E C+D C P P
Sbjct: 358 ACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPC 417
Query: 1584 DACKL 1588
AC+L
Sbjct: 418 RACRL 422
Score = 40.7 bits (91), Expect = 0.055
Identities = 16/47 (34%), Positives = 21/47 (44%)
Query: 1905 GPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSG 1951
GP + +V W YD R C F GC G F + + C+ C G
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG 354
>BC101602-1|AAI01603.1| 548|Homo sapiens WAP, follistatin/kazal,
immunoglobulin, kunitz and netrin domain containing 1,
protein.
Length = 548
Score = 108 bits (259), Expect = 2e-22
Identities = 49/108 (45%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 1534 GSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKG 1593
G + V W+YD + GGC F G DG F T E C C + P DAC LP V+G
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR-GPGDACVLPAVQG 366
Query: 1594 ACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPART 1641
C G+ RW Y +QC FVYGGC GN NNF +RE C+ C RT
Sbjct: 367 PCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRT 414
Score = 101 bits (242), Expect = 3e-20
Identities = 53/130 (40%), Positives = 68/130 (52%), Gaps = 10/130 (7%)
Query: 1580 PSPKDACKLPKVKGACVG----YNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQ 1635
P+P + LP V+ AC G + V W+YD +R C F GC G A F+T E CQ
Sbjct: 294 PAPAEC--LPDVQ-ACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQA 350
Query: 1636 CEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
C D C LP +G C G PRW ++ Q+C F++GGCEGN N F S +C+ C
Sbjct: 351 CARG-PGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Query: 1696 DPPGTLQPRC 1705
P T P C
Sbjct: 410 PVPRT--PPC 417
Score = 86.6 bits (205), Expect = 8e-16
Identities = 40/102 (39%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 1848 GPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-HFTQDVCQLPMLAGP 1906
GP + W YD + G C F GC G F + E CQ C D C LP + GP
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQGP 367
Query: 1907 CNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C W Y C F YGGC GN N F SR+ CE C
Sbjct: 368 CRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 85.0 bits (201), Expect = 3e-15
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLCTLPAETGECANYEEK 1779
+W + P G C F GC G FE AC +C D C LPA G C +E +
Sbjct: 316 LWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG-PGDACVLPAVQGPCRGWEPR 374
Query: 1780 WFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
W Y ++C F YGGC GN N F+S+ CE C
Sbjct: 375 WAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 74.5 bits (175), Expect = 4e-12
Identities = 36/102 (35%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Query: 1661 WGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP-PGTLQPRCSQPREQGGCNETAA 1719
W ++ + C F GC+G + F + AC+Q C PG C P QG C
Sbjct: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDA---CVLPAVQGPCRGWEP 373
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
W +SP +C PF Y GC GN N F +C +CP P P
Sbjct: 374 RWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTP 415
Score = 70.1 bits (164), Expect = 8e-11
Identities = 45/144 (31%), Positives = 60/144 (41%), Gaps = 22/144 (15%)
Query: 1748 EAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQ 1807
+AA + P +PD+ A TG + + W YD C F GC G F +
Sbjct: 288 DAAPSIPAPAECLPDV---QACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETY 344
Query: 1808 IECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCA 1867
C+ C+ GP ++ C GPC +E RW+Y +C
Sbjct: 345 EACQQACAR-----------------GPGDA--CVLPAVQGPCRGWEPRWAYSPLLQQCH 385
Query: 1868 PFQYGGCGGNTNNFASEEHCQYYC 1891
PF YGGC GN NNF S E C+ C
Sbjct: 386 PFVYGGCEGNGNNFHSRESCEDAC 409
Score = 68.5 bits (160), Expect = 2e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 1985 EVSPTLERCVAPG----LVWYLDAARRECVVHSNAESGLTCRNTGTFQTQEACERSCGAF 2040
E P ++ C P ++W+ D R C+ R F+T EAC+++C
Sbjct: 298 ECLPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARG---FETYEACQQACARG 354
Query: 2041 KDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+ C+ P GPCR + P++ + + C FVYGGC G N F + C + C
Sbjct: 355 PG-DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 53.2 bits (122), Expect = 1e-05
Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1526 ACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQP--SPK 1583
AC L +G R + W Y C F YGG +GNGN F ++E C+D C P P
Sbjct: 358 ACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPC 417
Query: 1584 DACKL 1588
AC+L
Sbjct: 418 RACRL 422
Score = 40.7 bits (91), Expect = 0.055
Identities = 16/47 (34%), Positives = 21/47 (44%)
Query: 1905 GPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSG 1951
GP + +V W YD R C F GC G F + + C+ C G
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG 354
>AF422194-1|AAL18839.1| 548|Homo sapiens putative multivalent
protease inhibitor WFIKKN protein.
Length = 548
Score = 108 bits (259), Expect = 2e-22
Identities = 49/108 (45%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 1534 GSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKG 1593
G + V W+YD + GGC F G DG F T E C C + P DAC LP V+G
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR-GPGDACVLPAVQG 366
Query: 1594 ACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPART 1641
C G+ RW Y +QC FVYGGC GN NNF +RE C+ C RT
Sbjct: 367 PCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRT 414
Score = 101 bits (242), Expect = 3e-20
Identities = 53/130 (40%), Positives = 68/130 (52%), Gaps = 10/130 (7%)
Query: 1580 PSPKDACKLPKVKGACVG----YNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQ 1635
P+P + LP V+ AC G + V W+YD +R C F GC G A F+T E CQ
Sbjct: 294 PAPAEC--LPDVQ-ACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQA 350
Query: 1636 CEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
C D C LP +G C G PRW ++ Q+C F++GGCEGN N F S +C+ C
Sbjct: 351 CARG-PGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Query: 1696 DPPGTLQPRC 1705
P T P C
Sbjct: 410 PVPRT--PPC 417
Score = 86.6 bits (205), Expect = 8e-16
Identities = 40/102 (39%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 1848 GPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-HFTQDVCQLPMLAGP 1906
GP + W YD + G C F GC G F + E CQ C D C LP + GP
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQGP 367
Query: 1907 CNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C W Y C F YGGC GN N F SR+ CE C
Sbjct: 368 CRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 85.0 bits (201), Expect = 3e-15
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLCTLPAETGECANYEEK 1779
+W + P G C F GC G FE AC +C D C LPA G C +E +
Sbjct: 316 LWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG-PGDACVLPAVQGPCRGWEPR 374
Query: 1780 WFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
W Y ++C F YGGC GN N F+S+ CE C
Sbjct: 375 WAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 74.5 bits (175), Expect = 4e-12
Identities = 36/102 (35%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Query: 1661 WGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP-PGTLQPRCSQPREQGGCNETAA 1719
W ++ + C F GC+G + F + AC+Q C PG C P QG C
Sbjct: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDA---CVLPAVQGPCRGWEP 373
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
W +SP +C PF Y GC GN N F +C +CP P P
Sbjct: 374 RWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTP 415
Score = 70.1 bits (164), Expect = 8e-11
Identities = 45/144 (31%), Positives = 60/144 (41%), Gaps = 22/144 (15%)
Query: 1748 EAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQ 1807
+AA + P +PD+ A TG + + W YD C F GC G F +
Sbjct: 288 DAAPSIPAPAECLPDV---QACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETY 344
Query: 1808 IECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCA 1867
C+ C+ GP ++ C GPC +E RW+Y +C
Sbjct: 345 EACQQACAR-----------------GPGDA--CVLPAVQGPCRGWEPRWAYSPLLQQCH 385
Query: 1868 PFQYGGCGGNTNNFASEEHCQYYC 1891
PF YGGC GN NNF S E C+ C
Sbjct: 386 PFVYGGCEGNGNNFHSRESCEDAC 409
Score = 68.5 bits (160), Expect = 2e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 1985 EVSPTLERCVAPG----LVWYLDAARRECVVHSNAESGLTCRNTGTFQTQEACERSCGAF 2040
E P ++ C P ++W+ D R C+ R F+T EAC+++C
Sbjct: 298 ECLPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARG---FETYEACQQACARG 354
Query: 2041 KDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+ C+ P GPCR + P++ + + C FVYGGC G N F + C + C
Sbjct: 355 PG-DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409
Score = 53.2 bits (122), Expect = 1e-05
Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1526 ACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQP--SPK 1583
AC L +G R + W Y C F YGG +GNGN F ++E C+D C P P
Sbjct: 358 ACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPC 417
Query: 1584 DACKL 1588
AC+L
Sbjct: 418 RACRL 422
Score = 40.7 bits (91), Expect = 0.055
Identities = 16/47 (34%), Positives = 21/47 (44%)
Query: 1905 GPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSG 1951
GP + +V W YD R C F GC G F + + C+ C G
Sbjct: 308 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG 354
>AE006464-5|AAK61237.1| 491|Homo sapiens unknown protein.
Length = 491
Score = 108 bits (259), Expect = 2e-22
Identities = 49/108 (45%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Query: 1534 GSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKG 1593
G + V W+YD + GGC F G DG F T E C C + P DAC LP V+G
Sbjct: 251 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACAR-GPGDACVLPAVQG 309
Query: 1594 ACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPART 1641
C G+ RW Y +QC FVYGGC GN NNF +RE C+ C RT
Sbjct: 310 PCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRT 357
Score = 101 bits (242), Expect = 3e-20
Identities = 53/130 (40%), Positives = 68/130 (52%), Gaps = 10/130 (7%)
Query: 1580 PSPKDACKLPKVKGACVG----YNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQ 1635
P+P + LP V+ AC G + V W+YD +R C F GC G A F+T E CQ
Sbjct: 237 PAPAEC--LPDVQ-ACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQA 293
Query: 1636 CEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
C D C LP +G C G PRW ++ Q+C F++GGCEGN N F S +C+ C
Sbjct: 294 CARG-PGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 352
Query: 1696 DPPGTLQPRC 1705
P T P C
Sbjct: 353 PVPRT--PPC 360
Score = 86.6 bits (205), Expect = 8e-16
Identities = 40/102 (39%), Positives = 45/102 (44%), Gaps = 1/102 (0%)
Query: 1848 GPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-HFTQDVCQLPMLAGP 1906
GP + W YD + G C F GC G F + E CQ C D C LP + GP
Sbjct: 251 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQGP 310
Query: 1907 CNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C W Y C F YGGC GN N F SR+ CE C
Sbjct: 311 CRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 352
Score = 85.0 bits (201), Expect = 3e-15
Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 1/95 (1%)
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVPDLCTLPAETGECANYEEK 1779
+W + P G C F GC G FE AC +C D C LPA G C +E +
Sbjct: 259 LWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG-PGDACVLPAVQGPCRGWEPR 317
Query: 1780 WFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
W Y ++C F YGGC GN N F+S+ CE C
Sbjct: 318 WAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 352
Score = 74.5 bits (175), Expect = 4e-12
Identities = 36/102 (35%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Query: 1661 WGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP-PGTLQPRCSQPREQGGCNETAA 1719
W ++ + C F GC+G + F + AC+Q C PG C P QG C
Sbjct: 260 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDA---CVLPAVQGPCRGWEP 316
Query: 1720 VWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
W +SP +C PF Y GC GN N F +C +CP P P
Sbjct: 317 RWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTP 358
Score = 70.1 bits (164), Expect = 8e-11
Identities = 45/144 (31%), Positives = 60/144 (41%), Gaps = 22/144 (15%)
Query: 1748 EAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQ 1807
+AA + P +PD+ A TG + + W YD C F GC G F +
Sbjct: 231 DAAPSIPAPAECLPDV---QACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETY 287
Query: 1808 IECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCA 1867
C+ C+ GP ++ C GPC +E RW+Y +C
Sbjct: 288 EACQQACAR-----------------GPGDA--CVLPAVQGPCRGWEPRWAYSPLLQQCH 328
Query: 1868 PFQYGGCGGNTNNFASEEHCQYYC 1891
PF YGGC GN NNF S E C+ C
Sbjct: 329 PFVYGGCEGNGNNFHSRESCEDAC 352
Score = 68.5 bits (160), Expect = 2e-10
Identities = 34/116 (29%), Positives = 53/116 (45%), Gaps = 8/116 (6%)
Query: 1985 EVSPTLERCVAPG----LVWYLDAARRECVVHSNAESGLTCRNTGTFQTQEACERSCGAF 2040
E P ++ C P ++W+ D R C+ R F+T EAC+++C
Sbjct: 241 ECLPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARG---FETYEACQQACARG 297
Query: 2041 KDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+ C+ P GPCR + P++ + + C FVYGGC G N F + C + C
Sbjct: 298 PG-DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 352
Score = 53.2 bits (122), Expect = 1e-05
Identities = 26/65 (40%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1526 ACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQP--SPK 1583
AC L +G R + W Y C F YGG +GNGN F ++E C+D C P P
Sbjct: 301 ACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDACPVPRTPPC 360
Query: 1584 DACKL 1588
AC+L
Sbjct: 361 RACRL 365
Score = 40.7 bits (91), Expect = 0.055
Identities = 16/47 (34%), Positives = 21/47 (44%)
Query: 1905 GPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSG 1951
GP + +V W YD R C F GC G F + + C+ C G
Sbjct: 251 GPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARG 297
>BC015514-1|AAH15514.1| 251|Homo sapiens tissue factor pathway
inhibitor (lipoprotein-associated coagulation inhibitor)
protein.
Length = 251
Score = 106 bits (255), Expect = 7e-22
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCS 1815
P + C A+ G C +++F++ ++C +F YGGC GN+N+F S EC+ C+
Sbjct: 46 PLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCT 105
Query: 1816 EIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCG 1875
+Q ++P +FCF E DPG C + TR+ Y+ + +C F+YGGC
Sbjct: 106 R-DNANRIIKTTLQQEKP-----DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCL 159
Query: 1876 GNTNNFASEEHCQYYC 1891
GN NNF + E C+ C
Sbjct: 160 GNMNNFETLEECKNIC 175
Score = 94.3 bits (224), Expect = 4e-18
Identities = 48/135 (35%), Positives = 73/135 (54%), Gaps = 14/135 (10%)
Query: 1517 TDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECD 1574
T++P K + C+ D G + +++++ C F YGG +GN NRF + EEC
Sbjct: 42 TELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECK 101
Query: 1575 DVC------------VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN 1622
+C +Q D C L + G C GY R++Y+++ +QC +F YGGCLGN
Sbjct: 102 KMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGN 161
Query: 1623 ANNFDTRELCQSQCE 1637
NNF+T E C++ CE
Sbjct: 162 MNNFETLEECKNICE 176
Score = 84.6 bits (200), Expect = 3e-15
Identities = 41/124 (33%), Positives = 57/124 (45%), Gaps = 12/124 (9%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFV---- 1760
C+ + G C ++F+ +C F Y GC GNQNRFE C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1761 --------PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECES 1812
PD C L + G C Y ++FY+ K+C +F YGGC GN N F + EC++
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1813 RCSE 1816
C +
Sbjct: 174 ICED 177
Score = 84.2 bits (199), Expect = 5e-15
Identities = 44/126 (34%), Positives = 57/126 (45%), Gaps = 14/126 (11%)
Query: 1840 FCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-------- 1891
FC F+ D GPC R+ ++ +C F YGGC GN N F S E C+ C
Sbjct: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRI 112
Query: 1892 ------HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
D C L G C I +FY+ C +F YGGC GN N F + +EC+
Sbjct: 113 IKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECK 172
Query: 1946 SRCRSG 1951
+ C G
Sbjct: 173 NICEDG 178
Score = 83.8 bits (198), Expect = 6e-15
Identities = 43/130 (33%), Positives = 61/130 (46%), Gaps = 13/130 (10%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK--- 1642
C G C R++++ QC +F+YGGC GN N F++ E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1643 ---------DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQ 1693
D C L + G C G R+ +N++T++CE F +GGC GN N F + CK
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1694 RC-DPPGTLQ 1702
C D P Q
Sbjct: 174 ICEDGPNGFQ 183
Score = 79.4 bits (187), Expect = 1e-13
Identities = 43/124 (34%), Positives = 58/124 (46%), Gaps = 11/124 (8%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG----- 1699
C+ + G C R+ FN T++CEEFI+GGCEGN NRF S CK+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1700 --TLQPR----CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
TLQ C + G C ++++ +C F Y GC GN N FE C +
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1754 SCPE 1757
C +
Sbjct: 174 ICED 177
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/51 (43%), Positives = 35/51 (68%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C + D GPC+A + +++F+ R C+EF+YGGC G NRF ++ EC ++C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
C DPG CR Y+ +Y+++N+ + C+ F YGGC G N F T+ EC +C++
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
>AF021834-1|AAD01700.1| 251|Homo sapiens tissue factor pathway
inhibitor beta protein.
Length = 251
Score = 106 bits (255), Expect = 7e-22
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCS 1815
P + C A+ G C +++F++ ++C +F YGGC GN+N+F S EC+ C+
Sbjct: 46 PLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCT 105
Query: 1816 EIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCG 1875
+Q ++P +FCF E DPG C + TR+ Y+ + +C F+YGGC
Sbjct: 106 R-DNANRIIKTTLQQEKP-----DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCL 159
Query: 1876 GNTNNFASEEHCQYYC 1891
GN NNF + E C+ C
Sbjct: 160 GNMNNFETLEECKNIC 175
Score = 94.3 bits (224), Expect = 4e-18
Identities = 48/135 (35%), Positives = 73/135 (54%), Gaps = 14/135 (10%)
Query: 1517 TDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECD 1574
T++P K + C+ D G + +++++ C F YGG +GN NRF + EEC
Sbjct: 42 TELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECK 101
Query: 1575 DVC------------VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN 1622
+C +Q D C L + G C GY R++Y+++ +QC +F YGGCLGN
Sbjct: 102 KMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGN 161
Query: 1623 ANNFDTRELCQSQCE 1637
NNF+T E C++ CE
Sbjct: 162 MNNFETLEECKNICE 176
Score = 84.6 bits (200), Expect = 3e-15
Identities = 41/124 (33%), Positives = 57/124 (45%), Gaps = 12/124 (9%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFV---- 1760
C+ + G C ++F+ +C F Y GC GNQNRFE C C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1761 --------PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECES 1812
PD C L + G C Y ++FY+ K+C +F YGGC GN N F + EC++
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1813 RCSE 1816
C +
Sbjct: 174 ICED 177
Score = 84.2 bits (199), Expect = 5e-15
Identities = 44/126 (34%), Positives = 57/126 (45%), Gaps = 14/126 (11%)
Query: 1840 FCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-------- 1891
FC F+ D GPC R+ ++ +C F YGGC GN N F S E C+ C
Sbjct: 53 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRI 112
Query: 1892 ------HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
D C L G C I +FY+ C +F YGGC GN N F + +EC+
Sbjct: 113 IKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECK 172
Query: 1946 SRCRSG 1951
+ C G
Sbjct: 173 NICEDG 178
Score = 83.8 bits (198), Expect = 6e-15
Identities = 43/130 (33%), Positives = 61/130 (46%), Gaps = 13/130 (10%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK--- 1642
C G C R++++ QC +F+YGGC GN N F++ E C+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1643 ---------DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQ 1693
D C L + G C G R+ +N++T++CE F +GGC GN N F + CK
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1694 RC-DPPGTLQ 1702
C D P Q
Sbjct: 174 ICEDGPNGFQ 183
Score = 79.4 bits (187), Expect = 1e-13
Identities = 43/124 (34%), Positives = 58/124 (46%), Gaps = 11/124 (8%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG----- 1699
C+ + G C R+ FN T++CEEFI+GGCEGN NRF S CK+ C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 113
Query: 1700 --TLQPR----CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
TLQ C + G C ++++ +C F Y GC GN N FE C +
Sbjct: 114 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 173
Query: 1754 SCPE 1757
C +
Sbjct: 174 ICED 177
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/51 (43%), Positives = 35/51 (68%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C + D GPC+A + +++F+ R C+EF+YGGC G NRF ++ EC ++C
Sbjct: 54 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
C DPG CR Y+ +Y+++N+ + C+ F YGGC G N F T+ EC +C++
Sbjct: 125 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 177
>AB209866-1|BAD93103.1| 201|Homo sapiens tissue factor pathway
inhibitor (lipoprotein-associated coagulation inhibitor)
protein.
Length = 201
Score = 106 bits (255), Expect = 7e-22
Identities = 47/136 (34%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCS 1815
P + C A+ G C +++F++ ++C +F YGGC GN+N+F S EC+ C+
Sbjct: 57 PLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCT 116
Query: 1816 EIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCG 1875
+Q ++P +FCF E DPG C + TR+ Y+ + +C F+YGGC
Sbjct: 117 R-DNANRIIKTTLQQEKP-----DFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCL 170
Query: 1876 GNTNNFASEEHCQYYC 1891
GN NNF + E C+ C
Sbjct: 171 GNMNNFETLEECKNIC 186
Score = 95.9 bits (228), Expect = 1e-18
Identities = 49/138 (35%), Positives = 74/138 (53%), Gaps = 14/138 (10%)
Query: 1517 TDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECD 1574
T++P K + C+ D G + +++++ C F YGG +GN NRF + EEC
Sbjct: 53 TELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECK 112
Query: 1575 DVC------------VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGN 1622
+C +Q D C L + G C GY R++Y+++ +QC +F YGGCLGN
Sbjct: 113 KMCTRDNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGN 172
Query: 1623 ANNFDTRELCQSQCEPAR 1640
NNF+T E C++ CE R
Sbjct: 173 MNNFETLEECKNICEDGR 190
Score = 86.2 bits (204), Expect = 1e-15
Identities = 45/127 (35%), Positives = 58/127 (45%), Gaps = 14/127 (11%)
Query: 1840 FCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC-------- 1891
FC F+ D GPC R+ ++ +C F YGGC GN N F S E C+ C
Sbjct: 64 FCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRI 123
Query: 1892 ------HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
D C L G C I +FY+ C +F YGGC GN N F + +EC+
Sbjct: 124 IKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECK 183
Query: 1946 SRCRSGR 1952
+ C GR
Sbjct: 184 NICEDGR 190
Score = 84.6 bits (200), Expect = 3e-15
Identities = 41/124 (33%), Positives = 57/124 (45%), Gaps = 12/124 (9%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFV---- 1760
C+ + G C ++F+ +C F Y GC GNQNRFE C C
Sbjct: 65 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 124
Query: 1761 --------PDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECES 1812
PD C L + G C Y ++FY+ K+C +F YGGC GN N F + EC++
Sbjct: 125 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 184
Query: 1813 RCSE 1816
C +
Sbjct: 185 ICED 188
Score = 83.4 bits (197), Expect = 8e-15
Identities = 40/123 (32%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 1586 CKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK--- 1642
C G C R++++ QC +F+YGGC GN N F++ E C+ C
Sbjct: 65 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 124
Query: 1643 ---------DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQ 1693
D C L + G C G R+ +N++T++CE F +GGC GN N F + CK
Sbjct: 125 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 184
Query: 1694 RCD 1696
C+
Sbjct: 185 ICE 187
Score = 79.4 bits (187), Expect = 1e-13
Identities = 43/124 (34%), Positives = 58/124 (46%), Gaps = 11/124 (8%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPG----- 1699
C+ + G C R+ FN T++CEEFI+GGCEGN NRF S CK+ C
Sbjct: 65 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMCTRDNANRII 124
Query: 1700 --TLQPR----CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
TLQ C + G C ++++ +C F Y GC GN N FE C +
Sbjct: 125 KTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKN 184
Query: 1754 SCPE 1757
C +
Sbjct: 185 ICED 188
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/51 (43%), Positives = 35/51 (68%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C + D GPC+A + +++F+ R C+EF+YGGC G NRF ++ EC ++C
Sbjct: 65 CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 115
Score = 66.9 bits (156), Expect = 7e-10
Identities = 22/53 (41%), Positives = 34/53 (64%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
C DPG CR Y+ +Y+++N+ + C+ F YGGC G N F T+ EC +C++
Sbjct: 136 CFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFETLEECKNICED 188
>AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein.
Length = 659
Score = 103 bits (247), Expect = 7e-21
Identities = 61/178 (34%), Positives = 81/178 (45%), Gaps = 10/178 (5%)
Query: 1468 CEQSQYGCCGDGETHATGPNLGGCD---CSTSKYGCCPDGQTLAEGPKFFGCTDIPENKQ 1524
C S +GCC DG T + GP GC C S+YGCCPD ++AEGP GCT
Sbjct: 11 CRHSPHGCCPDGHTASLGPQWQGCPGAPCQQSRYGCCPDRVSVAEGPHHAGCTKSYGGDS 70
Query: 1525 VACSLAKDRGSGRDYSVY--WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCV-QPS 1581
+ ++ + E C +G N A + CV QPS
Sbjct: 71 TGGRPRSRAVASTVHNTHQPQAQQNEPSECRGSQFGCCYDNVATAA--GPLGEGCVGQPS 128
Query: 1582 P--KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
C LP G+C + RWY+ + QC++F YGGC GNANNF + + C S C+
Sbjct: 129 HAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQ 186
Score = 83.8 bits (198), Expect = 6e-15
Identities = 72/231 (31%), Positives = 92/231 (39%), Gaps = 33/231 (14%)
Query: 1489 GGCDCSTSKYGCCPDGQTLAEGPKFFGCTDIP-ENKQVACSLAKDRGSGRDYSVYWYYDM 1547
G DC S +GCCPDG T + GP++ GC P + + C DR S +
Sbjct: 7 GPHDCRHSPHGCCPDGHTASLGPQWQGCPGAPCQQSRYGC--CPDRVSVAE-------GP 57
Query: 1548 EYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSE 1607
+ GC++ YGG D G R ++ V P+ P C G YD+
Sbjct: 58 HHAGCTKS-YGG-DSTGGRPRSRAVASTVHNTHQPQAQQNEP---SECRGSQFGCCYDNV 112
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDET 1667
+ GC+G S P R C LP GSCA RW F
Sbjct: 113 ATAAGP-LGEGCVGQ----------PSHAYPVR----CLLPSAHGSCADWAARWYFVASV 157
Query: 1668 QRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQ-PRCSQPREQGGCNET 1717
+C F +GGC GN+N F SE C C G+L PR QP G T
Sbjct: 158 GQCNRFWYGGCHGNANNFASEQECMSSCQ--GSLHGPRRPQPGASGRSTHT 206
Score = 78.6 bits (185), Expect = 2e-13
Identities = 41/114 (35%), Positives = 54/114 (47%), Gaps = 3/114 (2%)
Query: 1143 CATTKFGCCPDKRTAASGPFDEGCEKVRTCKETRFGCCSDGVSAALGPEEKGCPPSLCAE 1202
C + GCCPD TA+ GP +GC C+++R+GCC D VS A GP GC S +
Sbjct: 11 CRHSPHGCCPDGHTASLGPQWQGCPGA-PCQQSRYGCCPDRVSVAEGPHHAGCTKSYGGD 69
Query: 1203 SLFGCCLSD--NKTAAGGNDQEGCPPMPPACKLAPYGCCADGETEATGPDFSGC 1254
S G S T + + P C+ + +GCC D A GP GC
Sbjct: 70 STGGRPRSRAVASTVHNTHQPQAQQNEPSECRGSQFGCCYDNVATAAGPLGEGC 123
Score = 74.1 bits (174), Expect = 5e-12
Identities = 44/130 (33%), Positives = 53/130 (40%), Gaps = 18/130 (13%)
Query: 1341 PLTCATSRFGCCPDDVTPAHGPDGEGC----CLIYPFGCCPDNFKVADGPNFAGCDCHYG 1396
P C S GCCPD T + GP +GC C +GCCPD VA+GP+ AGC YG
Sbjct: 8 PHDCRHSPHGCCPDGHTASLGPQWQGCPGAPCQQSRYGCCPDRVSVAEGPHHAGCTKSYG 67
Query: 1397 RFGCCPDNTTYARGPANXXXXXXXXXXXXXPDRHTPATGPDREGCGCHTYQFGCCPDGVT 1456
G + + H P E C QFGCC D V
Sbjct: 68 -------------GDSTGGRPRSRAVASTVHNTHQPQA-QQNEPSECRGSQFGCCYDNVA 113
Query: 1457 ISKGPGLQGC 1466
+ GP +GC
Sbjct: 114 TAAGPLGEGC 123
Score = 71.3 bits (167), Expect = 3e-11
Identities = 37/114 (32%), Positives = 46/114 (40%), Gaps = 3/114 (2%)
Query: 1190 PEEKGCPPSLCAESLFGCCLSDNKTAAGGNDQEGCPPMPPACKLAPYGCCADGETEATGP 1249
P G P C S GCC D TA+ G +GCP P C+ + YGCC D + A GP
Sbjct: 1 PLRSGSGPHDCRHSPHGCC-PDGHTASLGPQWQGCPGAP--CQQSRYGCCPDRVSVAEGP 57
Query: 1250 DFSGCPEHXXXXXXXXXXXXXXXXXXXXXXXAVHSTTVSGEDCAGSAFGCCYDN 1303
+GC + + +C GS FGCCYDN
Sbjct: 58 HHAGCTKSYGGDSTGGRPRSRAVASTVHNTHQPQAQQNEPSECRGSQFGCCYDN 111
Score = 69.3 bits (162), Expect = 1e-10
Identities = 39/102 (38%), Positives = 47/102 (46%), Gaps = 13/102 (12%)
Query: 1323 GCCPDNHTPAEDAEMKGCP-LTCATSRFGCCPDDVTPAHGPDGEGCCLIY---PFGCCPD 1378
GCCPD HT + + +GCP C SR+GCCPD V+ A GP GC Y G P
Sbjct: 17 GCCPDGHTASLGPQWQGCPGAPCQQSRYGCCPDRVSVAEGPHHAGCTKSYGGDSTGGRPR 76
Query: 1379 NFKVA---------DGPNFAGCDCHYGRFGCCPDNTTYARGP 1411
+ VA +C +FGCC DN A GP
Sbjct: 77 SRAVASTVHNTHQPQAQQNEPSECRGSQFGCCYDNVATAAGP 118
Score = 64.5 bits (150), Expect = 4e-09
Identities = 25/59 (42%), Positives = 35/59 (59%)
Query: 1756 PEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
P P C LP+ G CA++ +W++ S +C +F+YGGC GN N F S+ EC S C
Sbjct: 127 PSHAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 185
Score = 61.7 bits (143), Expect = 3e-08
Identities = 34/87 (39%), Positives = 40/87 (45%), Gaps = 3/87 (3%)
Query: 1866 CAPFQYGGCGGNTNNFASE--EHCQYYCHFTQDV-CQLPMLAGPCNDSIVSWFYDASRDA 1922
C Q+G C N A E C V C LP G C D W++ AS
Sbjct: 100 CRGSQFGCCYDNVATAAGPLGEGCVGQPSHAYPVRCLLPSAHGSCADWAARWYFVASVGQ 159
Query: 1923 CSQFAYGGCGGNDNRFASRDECESRCR 1949
C++F YGGC GN N FAS EC S C+
Sbjct: 160 CNRFWYGGCHGNANNFASEQECMSSCQ 186
Score = 60.5 bits (140), Expect = 6e-08
Identities = 24/52 (46%), Positives = 29/52 (55%)
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
RC P G C + AA W+F + G+C F+Y GC GN N F E C SSC
Sbjct: 134 RCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 185
Score = 58.4 bits (135), Expect = 3e-07
Identities = 25/60 (41%), Positives = 30/60 (50%)
Query: 1832 QPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
QP C + G C + RW + A G+C F YGGC GN NNFASE+ C C
Sbjct: 126 QPSHAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSC 185
Score = 50.4 bits (115), Expect = 7e-05
Identities = 20/52 (38%), Positives = 26/52 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
CL P G C + ++YF C F YGGCHG N F++ EC C+
Sbjct: 135 CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQ 186
Score = 46.0 bits (104), Expect = 0.001
Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 13/114 (11%)
Query: 1291 DCAGSAFGCCYDNQTXXXXXXXXXXXXX---XTKFGCCPDNHTPAEDAEMKGCPLTCATS 1347
DC S GCC D T +++GCCPD + AE GC +
Sbjct: 10 DCRHSPHGCCPDGHTASLGPQWQGCPGAPCQQSRYGCCPDRVSVAEGPHHAGCTKSYGGD 69
Query: 1348 RFGCCP------DDVTPAHGPDGE----GCCLIYPFGCCPDNFKVADGPNFAGC 1391
G P V H P + C FGCC DN A GP GC
Sbjct: 70 STGGRPRSRAVASTVHNTHQPQAQQNEPSECRGSQFGCCYDNVATAAGPLGEGC 123
Score = 34.7 bits (76), Expect = 3.6
Identities = 12/25 (48%), Positives = 16/25 (64%)
Query: 1142 KCATTKFGCCPDKRTAASGPFDEGC 1166
+C ++FGCC D A+GP EGC
Sbjct: 99 ECRGSQFGCCYDNVATAAGPLGEGC 123
>BC042057-1|AAH42057.1| 129|Homo sapiens PAPLN protein protein.
Length = 129
Score = 102 bits (245), Expect = 1e-20
Identities = 39/86 (45%), Positives = 56/86 (65%)
Query: 56 TPCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYN 115
+PCSRTCGGGV+ ++R C +G C G + SC T+ CP+ + DFRAEQCA+++
Sbjct: 36 SPCSRTCGGGVSFRERPCYSQRRDGGSSCVGPARSHRSCRTESCPDGARDFRAEQCAEFD 95
Query: 116 NVTFRGKKYRWVPYLKVSKPCELTCM 141
F+G++YRW+PY CEL C+
Sbjct: 96 GAEFQGRRYRWLPYYSAPNKCELNCI 121
Score = 35.5 bits (78), Expect = 2.1
Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 7/52 (13%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPA-TNQTCNTQACP 386
+S CS TCGGG+ R+ C S+ D G G PA ++++C T++CP
Sbjct: 35 WSPCSRTCGGGVSFRERPCYSQRR----DGGSSCVG--PARSHRSCRTESCP 80
>AF217974-1|AAG17217.1| 237|Homo sapiens unknown protein.
Length = 237
Score = 102 bits (244), Expect = 2e-20
Identities = 60/190 (31%), Positives = 83/190 (43%), Gaps = 19/190 (10%)
Query: 330 SWVHGNFSS-CSATCGGGIQSRDVTCRSREELEVVDEG--------LCDDGLKPATNQTC 380
+W H ++SS CSA CG GIQ R V C +G C G +P + C
Sbjct: 7 AWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRAC 66
Query: 381 NTQACPP--QWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKP 438
+ C +W G W CS CG GT+ R++ C + +V C L P+P
Sbjct: 67 SLGPCERTWRWYTGPWGECSSECGS-GTQRRDIICVSKLGTEF-NVTSPSNCSHL--PRP 122
Query: 439 ALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPL 498
+ C A WF +PW PC + C G QTR+V C N LS + +P
Sbjct: 123 PALQPCQGQACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTN----QTLSTRCPPQLRPS 178
Query: 499 DRQPCELEPC 508
++PC +PC
Sbjct: 179 RKRPCNSQPC 188
Score = 95.5 bits (227), Expect = 2e-18
Identities = 61/196 (31%), Positives = 89/196 (45%), Gaps = 18/196 (9%)
Query: 450 CPT-WFISPWKP-CDKLCGSGQQTRQVVCYQKN------NGRINVLSDDEC-SEEKPLDR 500
C T WF S W C CG+G Q R VVC G + C + +P D
Sbjct: 4 CTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDM 63
Query: 501 QPCELEPCEGV-DWMVSEWTGCDT-CLATVRSRVAQCVTK---DYRVVNSSFCSYHPTPA 555
+ C L PCE W W C + C + + R CV+K ++ V + S CS+ P P
Sbjct: 64 RACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPP 123
Query: 556 LEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEE 615
+PC ACQ +W++T WS CS C G +TR V C + + P +
Sbjct: 124 ALQPCQGQ---ACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRK 180
Query: 616 KYNDSKPC-EVPEEKC 630
+ +S+PC + P+++C
Sbjct: 181 RPCNSQPCSQRPDDQC 196
Score = 84.6 bits (200), Expect = 3e-15
Identities = 38/115 (33%), Positives = 54/115 (46%), Gaps = 3/115 (2%)
Query: 571 QWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
+WY W +CS ECG G + R + C G SNC + +PC+ + C
Sbjct: 76 RWYTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPALQPCQ--GQAC 133
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSD-CPKKSLPDSAGSCNEQSC 684
+W++ PWS C++SC G + R V CL + S CP + P CN Q C
Sbjct: 134 QDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPC 188
Score = 74.5 bits (175), Expect = 4e-12
Identities = 41/132 (31%), Positives = 60/132 (45%), Gaps = 15/132 (11%)
Query: 568 CQVQWYATQWS-KCSVECGVGKKTRRVFC-------GKFDGASVMKVDDSNCPKEEKYND 619
C W+ + WS KCS ECG G + R V C G G + S CP + D
Sbjct: 4 CTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQS-CPTGSRPPD 62
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEF-----SDCPKKSLP 673
+ C + + +WY PW EC+ CG G + R ++C+ + G EF S+C P
Sbjct: 63 MRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRP 122
Query: 674 DSAGSCNEQSCE 685
+ C Q+C+
Sbjct: 123 PALQPCQGQACQ 134
Score = 72.5 bits (170), Expect = 1e-11
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 325 PTQR-YSWVHGNFSSCSATCGGGIQSRDVTCRSR--EELEVVDEGLCDDGLKPATNQTCN 381
P +R + W G + CS+ CG G Q RD+ C S+ E V C +P Q C
Sbjct: 70 PCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPALQPCQ 129
Query: 382 TQACPPQWVPGNWSRCSKRCGKDGTRSREVRC 413
QAC +W WS CS+ C + GT++REV+C
Sbjct: 130 GQACQDRWFSTPWSPCSRSC-QGGTQTREVQC 160
>AB023177-1|BAA76804.2| 1502|Homo sapiens KIAA0960 protein protein.
Length = 1502
Score = 102 bits (244), Expect = 2e-20
Identities = 111/366 (30%), Positives = 156/366 (42%), Gaps = 43/366 (11%)
Query: 343 CGGGIQSRDVTCRSREELEVVDEGLCDDG--LKPATNQTCNTQACPPQWVPGNWSRCSKR 400
CG G + + + C + +V+ C+ ++ A C + +W NWSRCSK
Sbjct: 839 CGQGYRYQAMACYDQNG-RLVETSRCNSHGYIEEACIIPCPSDCKLSEW--SNWSRCSKS 895
Query: 401 CGKD-GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYE--SCNVDAACPTWFISP 457
CG RS+ +R EK G P D + +YE C+ D W P
Sbjct: 896 CGSGVKVRSKWLR-EKPYNGGRPCPKLDHV------NQAQVYEVVPCHSDCNQYLWVTEP 948
Query: 458 WKPCD-------KLCGSGQQTRQVVCYQKN-NGRINVLSDDECS-EEKPLDRQPCELEPC 508
W C + CG G QTR+V C Q +G + D C EE PL + C+L PC
Sbjct: 949 WSICKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEEMPLGSRVCKL-PC 1007
Query: 509 EGVDWMVSEWTGCDTC-LATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPA 567
D ++SEW C L +S Q R S P +EPC+ +K
Sbjct: 1008 P-EDCVISEWGPWTQCVLPCNQSSFRQRSADPIRQPADEGRSC-PNAVEKEPCNLNK-NC 1064
Query: 568 CQVQWYATQWSKCSVE----CGVGKKTRRVFCGKFDGASV-MKVDDS-NCPKEEKYNDSK 621
+ T WS C + CG G KTR + C + DG SV +K ++ K + N S
Sbjct: 1065 YHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEALGLEKNWQMNTSC 1124
Query: 622 PCEVPEEKCPSKWYAAPWSECTKSC---GKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGS 678
E P S W +PWSEC+++C GK +R R+V G + CP SL D +
Sbjct: 1125 MVECPVNCQLSDW--SPWSECSQTCGLTGKMIRRRTVTQPFQG-DGRPCP--SLMDQSKP 1179
Query: 679 CNEQSC 684
C + C
Sbjct: 1180 CPVKPC 1185
Score = 87.4 bits (207), Expect = 5e-16
Identities = 111/392 (28%), Positives = 151/392 (38%), Gaps = 72/392 (18%)
Query: 346 GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCN-TQACP-PQWVPGNWSRCSKRCGK 403
G Q+R+V C ++ + D C P T Q+C T+ C +W WS CSK C
Sbjct: 167 GYQTREVMCINKTG-KAADLSFCQQEKLPMTFQSCVITKECQVSEW--SEWSPCSKTC-H 222
Query: 404 DGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT--WFISPWKPC 461
D R P + +KEC + +P L + V C T W + W C
Sbjct: 223 DMVSPAGTRVRTRTIRQFP-IGSEKECPEFEEKEPCLSQGDGV-VPCATYGWRTTEWTEC 280
Query: 462 ---------DK-------LCGSGQQTRQVVCYQKNNGRINVLSDDECSE-EKPLDRQ--- 501
DK LCG G QTR+V C Q N ++ LS + E KP+D +
Sbjct: 281 RVDPLLSQQDKRRGNQTALCGGGIQTREVYCVQANENLLSQLSTHKNKEASKPMDLKLCT 340
Query: 502 ------------PCELEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCS 549
PC E CE W S W C + + R+ N
Sbjct: 341 GPIPNTTQLCHIPCPTE-CEVSPW--SAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGG 397
Query: 550 YHPT---PALEE--PCDKDKLPACQVQWYATQWSKCSV----ECGVGKKTRRVFCGKFDG 600
T P L E PC++ PAC W A + C ECG G + + V C DG
Sbjct: 398 SGVTGNCPHLLEAIPCEE---PACY-DWKAVRLGDCEPDNGKECGPGTQVQEVVCINSDG 453
Query: 601 ASVMKVDDSNCPKEEKYNDSKPCEVPEEK-CP-SKWYAAPWSECTKSC------GKGLRF 652
+VD C ++ + C+ P K C S W + WS C+ +C GK +R
Sbjct: 454 E---EVDRQLC-RDAIFPIPVACDAPCPKDCVLSTW--STWSSCSHTCSGKTTEGKQIRA 507
Query: 653 RSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSC 684
RS++ G + CP S SCNE C
Sbjct: 508 RSILAYAGEEGGIRCPNSSALQEVRSCNEHPC 539
Score = 84.6 bits (200), Expect = 3e-15
Identities = 93/360 (25%), Positives = 142/360 (39%), Gaps = 60/360 (16%)
Query: 328 RYSWVHGNFSSCSAT-------CGGGIQSRDVTCRSRE---ELEVVDEGLCDDGLKPATN 377
+Y WV +S C T CG G+Q+R V C E V++ LCD P +
Sbjct: 941 QYLWVTEPWSICKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEEMPLGS 1000
Query: 378 QTCNTQACPPQWVP---GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDD-KECFDL 433
+ C CP V G W++C C + R R + + D+ + C
Sbjct: 1001 RVCKL-PCPEDCVISEWGPWTQCVLPCNQSSFRQRS-------ADPIRQPADEGRSC--- 1049
Query: 434 LGPKPALYESCNVDAAC--PTWFISPWKPCD----KLCGSGQQTRQVVCYQKNNGRINVL 487
P E CN++ C + ++ W C +CG+G +TR + C + + +++
Sbjct: 1050 --PNAVEKEPCNLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLK 1107
Query: 488 SDDECSEEKPLD-RQPCELE---PCEGVDWMVSEWTGC-DTCLATVRSRVAQCVTKDYRV 542
+ EK C +E C+ DW S W+ C TC T + + VT+ ++
Sbjct: 1108 YCEALGLEKNWQMNTSCMVECPVNCQLSDW--SPWSECSQTCGLTGKMIRRRTVTQPFQ- 1164
Query: 543 VNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSV---ECGVGKKTRRVFCGKFD 599
P P+L + + C +W QWS C V +CG G +TR + C D
Sbjct: 1165 -----GDGRPCPSLMDQSKPCPVKPC-YRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSD 1218
Query: 600 GAS---VMKVDDSNCPKEEKYNDSKPCEVPEEK----CPSKWYAAPWSE---CTKSCGKG 649
G++ VD+ C E D V EE CP Y WS C +C G
Sbjct: 1219 GSADDFSKVVDEEFCADIELIIDGNKNMVLEESCSQPCPGDCYLKDWSSWSLCQLTCVNG 1278
Score = 78.2 bits (184), Expect = 3e-13
Identities = 99/358 (27%), Positives = 147/358 (41%), Gaps = 45/358 (12%)
Query: 343 CGGGIQSRDVTCRSREELEV-VDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSR---CS 398
CG G Q+R +TCR ++ + + E L G PA Q C C +WS+ C+
Sbjct: 706 CGPGRQARAITCRKQDGGQAGIHECLQYAGPVPALTQACQI-PCQDDCQLTSWSKFSSCN 764
Query: 399 KRCGKDGTRSREV-----RCEKIITNGLPSVVDDKEC-FDLLGPKP-ALYESCNVDAACP 451
CG TR R + + EK + L +++ + C D +P + C +
Sbjct: 765 GDCGAVRTRKRTLVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKV 824
Query: 452 TWFISPWKPCD-KLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ---PCELEP 507
+ D K CG G + + + CY + NGR+ + C+ ++ PC +
Sbjct: 825 EVLLGMKVQGDIKECGQGYRYQAMACYDQ-NGRL--VETSRCNSHGYIEEACIIPCPSD- 880
Query: 508 CEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPA-LEE--PCDKD 563
C+ +W S W+ C +C + V+ R K Y H A + E PC D
Sbjct: 881 CKLSEW--SNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSD 938
Query: 564 KLPACQVQWYATQWSKCSV-------ECGVGKKTRRVFC--GKFDGASVMKVDDSNCPKE 614
Q W WS C V CG G +TR+V C DG S V+D C E
Sbjct: 939 ---CNQYLWVTEPWSICKVTFVNMRENCGEGVQTRKVRCMQNTADGPS-EHVEDYLCDPE 994
Query: 615 EKYNDSKPCEVP-EEKCP-SKWYAAPWSECTKSCGK-GLRFRSVVCLR-GGKEFSDCP 668
E S+ C++P E C S+W PW++C C + R RS +R E CP
Sbjct: 995 EMPLGSRVCKLPCPEDCVISEW--GPWTQCVLPCNQSSFRQRSADPIRQPADEGRSCP 1050
Score = 66.5 bits (155), Expect = 1e-09
Identities = 101/400 (25%), Positives = 154/400 (38%), Gaps = 82/400 (20%)
Query: 329 YSWVHGNFSSCSAT----CGGGIQSRDVTCRSREELEVVDEGLCDDGLKP---ATNQTCN 381
Y W C CG G Q ++V C + + E VD LC D + P A + C
Sbjct: 419 YDWKAVRLGDCEPDNGKECGPGTQVQEVVCINSDG-EEVDRQLCRDAIFPIPVACDAPCP 477
Query: 382 TQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
W WS CS C T +++R I+ +E AL
Sbjct: 478 KDCVLSTW--STWSSCSHTCSGKTTEGKQIRARSILAYA------GEEGGIRCPNSSALQ 529
Query: 442 E--SCNVDAACPT--WFISPWKPC-----------------DKLCGSGQQTRQVVCYQKN 480
E SCN + C W PW C + C G QTR+V+C + N
Sbjct: 530 EVRSCN-EHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWNGEASCSVGMQTRKVICVRVN 588
Query: 481 NGRINVLSDDECSEE-KPLDRQPCELEPCEGVDWMV---SEWTGC-DTCL---ATVRSRV 532
G++ +C E +P +PC L PC+ D +V S+WT C +C +++R +
Sbjct: 589 VGQV---GPKKCPESLRPETVRPC-LLPCK-KDCIVTPYSDWTSCPSSCKEGDSSIRKQS 643
Query: 533 AQCVTKDYRVVNSSFCSYHPTPALEE-PCDKDKLPACQ-VQWYATQWSKC-----SVE-- 583
V C+ P EE C+ + ACQ +W +W +C SV+
Sbjct: 644 RHRVIIQLPANGGRDCT---DPLYEEKACEAPQ--ACQSYRWKTHKWRRCQLVPWSVQQD 698
Query: 584 -------CGVGKKTRRVFCGKFDG--ASVMKVDDSNCPKEEKYNDSKPCEVP-EEKCP-S 632
CG G++ R + C K DG A + + P ++ C++P ++ C +
Sbjct: 699 SPGAQEGCGPGRQARAITCRKQDGGQAGIHECLQYAGPVPAL---TQACQIPCQDDCQLT 755
Query: 633 KWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSL 672
W + +S C CG +R R + K+ C L
Sbjct: 756 SW--SKFSSCNGDCG-AVRTRKRTLVGKSKKKEKCKNSHL 792
Score = 57.6 bits (133), Expect = 4e-07
Identities = 98/408 (24%), Positives = 145/408 (35%), Gaps = 76/408 (18%)
Query: 336 FSSCSATCGGGIQSRDVTCRSR--EELEVVDEGLCDD--GLKPATNQTCNTQACPPQ-WV 390
+S CS TC + R+R + + E C + +P +Q C W
Sbjct: 214 WSPCSKTCHDMVSPAGTRVRTRTIRQFPIGSEKECPEFEEKEPCLSQGDGVVPCATYGWR 273
Query: 391 PGNWSRC---------SKRCGKD------GTRSREVRCEKIITNGLP--SVVDDKEC--- 430
W+ C KR G G ++REV C + N L S +KE
Sbjct: 274 TTEWTECRVDPLLSQQDKRRGNQTALCGGGIQTREVYCVQANENLLSQLSTHKNKEASKP 333
Query: 431 FDL---LGPKPALYESCNVDAACPTWF-ISPWK---PCDKLCGSGQQTRQVVCYQKNNGR 483
DL GP P + C++ CPT +SPW PC + QQ ++ +K
Sbjct: 334 MDLKLCTGPIPNTTQLCHIP--CPTECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRIT 391
Query: 484 INVLSDDECSEEKP--LDRQPCELEPCEGVDWMVSEWTGCDT-----CLATVRSRVAQCV 536
+ P L+ PCE C DW C+ C + + C+
Sbjct: 392 NEPTGGSGVTGNCPHLLEAIPCEEPAC--YDWKAVRLGDCEPDNGKECGPGTQVQEVVCI 449
Query: 537 TKDYRVVNSSFC--SYHPTP-ALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTR-R 592
D V+ C + P P A + PC KD C + ++T WS CS C GK T +
Sbjct: 450 NSDGEEVDRQLCRDAIFPIPVACDAPCPKD----CVLSTWST-WSSCSHTCS-GKTTEGK 503
Query: 593 VFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS-KWYAAPWSECTK------- 644
+ A + CP + + C E C W PW +C +
Sbjct: 504 QIRARSILAYAGEEGGIRCPNSSALQEVRSCN--EHPCTVYHWQTGPWGQCIEDTSVSSF 561
Query: 645 ----------SCGKGLRFRSVVCLR---GGKEFSDCPKKSLPDSAGSC 679
SC G++ R V+C+R G CP+ P++ C
Sbjct: 562 NTTTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPC 609
Score = 53.6 bits (123), Expect = 7e-06
Identities = 79/317 (24%), Positives = 122/317 (38%), Gaps = 44/317 (13%)
Query: 286 DKLRSLGPINEPLYLSLLLIDENVGVEYEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGG 345
D +RS G + Y L +++N + S +E P+ Q W +S CS TCG
Sbjct: 1095 DCVRSDGKSVDLKYCEALGLEKNW--QMNTSCMVE-CPVNCQLSDW--SPWSECSQTCG- 1148
Query: 346 GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWSRCS---KRCG 402
+ + + R+ + D C + + + C + C +W G WS C +CG
Sbjct: 1149 -LTGKMIRRRTVTQPFQGDGRPCPSLMDQS--KPCPVKPCY-RWQYGQWSPCQVQEAQCG 1204
Query: 403 KDGTRSREVRCEKIITNG----LPSVVDDKECFDLL----GPKP-ALYESCNV----DAA 449
+GTR+R + C ++++G VVD++ C D+ G K L ESC+ D
Sbjct: 1205 -EGTRTRNISC--VVSDGSADDFSKVVDEEFCADIELIIDGNKNMVLEESCSQPCPGDCY 1261
Query: 450 CPTWFISPWKPCDKLCGSGQQTR-QVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC 508
W S W C C +G+ + + I L + E+ L+ + C C
Sbjct: 1262 LKDW--SSWSLCQLTCVNGEDLGFGGIQVRSRPVIIQELENQHLCPEQMLETKSCYDGQC 1319
Query: 509 EGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPAC 568
WM S W G SR C D V C P + C+ P
Sbjct: 1320 YEYKWMASAWKG--------SSRTVWCQRSDGINVTGG-CLVMSQPDADRSCNP---PCS 1367
Query: 569 QVQWYATQWSKCSVECG 585
Q Y ++ C E G
Sbjct: 1368 QPHSYCSETKTCHCEEG 1384
Score = 46.8 bits (106), Expect = 8e-04
Identities = 57/217 (26%), Positives = 81/217 (37%), Gaps = 25/217 (11%)
Query: 436 PKPALYESCNVDAA--CPTWFISPWKPCDKLCGSGQQ--TRQVVCYQKNNGRINVLSDDE 491
PKP L ++C + C S W C K CGSG Q TR VV + G
Sbjct: 24 PKPLLEQACLIPCQQDCIVSEFSAWSECSKTCGSGLQHRTRHVVAPPQFGG-------SG 76
Query: 492 CSEEKPLDRQPCELEPCEGVDWMVSEWTG-CDTCLATVRSRVAQCVTKDYRVVNSSFCSY 550
C + Q C+ PCE + S G TC +V Q + S
Sbjct: 77 C--PNLTEFQVCQSSPCEAEELRYSLHVGPWSTCSMPHSRQVRQARRRGKNKEREKDRSK 134
Query: 551 H-PTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDS 609
P E K + Q + W + +G +TR V C G + D S
Sbjct: 135 GVKDPEARELIKKKRNRNRQNRQENKYW-----DIQIGYQTREVMCINKTGKA---ADLS 186
Query: 610 NCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSC 646
C +E+ + C + +E S+W + WS C+K+C
Sbjct: 187 FCQQEKLPMTFQSCVITKECQVSEW--SEWSPCSKTC 221
Score = 44.8 bits (101), Expect = 0.003
Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 18/128 (14%)
Query: 531 RVAQCVTKDYRV-VNSSFCSY-HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVG- 587
R C+ KD + C Y P P LE+ C C V ++ WS+CS CG G
Sbjct: 1 REIACIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSA-WSECSKTCGSGL 59
Query: 588 -KKTRRVFC-GKFDGASVMKVDDSNCPKEEKYN--DSKPCEVPEEKCPSKWYAAPWSECT 643
+TR V +F G S CP ++ S PCE E+ + PWS C+
Sbjct: 60 QHRTRHVVAPPQFGG--------SGCPNLTEFQVCQSSPCEA--EELRYSLHVGPWSTCS 109
Query: 644 KSCGKGLR 651
+ +R
Sbjct: 110 MPHSRQVR 117
Score = 34.7 bits (76), Expect = 3.6
Identities = 20/56 (35%), Positives = 33/56 (58%), Gaps = 10/56 (17%)
Query: 608 DSNCPKEE---KYNDSKP-----CEVP-EEKCPSKWYAAPWSECTKSCGKGLRFRS 654
D + P E+ +Y + KP C +P ++ C ++A WSEC+K+CG GL+ R+
Sbjct: 9 DKDIPAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSA-WSECSKTCGSGLQHRT 63
>BC034155-1|AAH34155.1| 167|Homo sapiens Similar to tissue factor
pathway inhibitor 2 protein.
Length = 167
Score = 98.3 bits (234), Expect = 3e-19
Identities = 50/141 (35%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Query: 1619 CLGNANNFDTRELCQSQC-EPARTKDQCSLPIE-RGSCAGNFPRWGFNDETQRCEEFIWG 1676
C GNANNF T E C C + C L + C G+ ++ FN + CE+F G
Sbjct: 1 CEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSG 60
Query: 1677 GCEGN--SNRFGSEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFY 1734
GC N NRF EA C C P + C P+++G C+ ++F+P C F
Sbjct: 61 GCHRNRIENRFPDEATCMGFC-APKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFT 119
Query: 1735 YSGCGGNQNRFEDEAACASSC 1755
Y+GCGGN N F C +C
Sbjct: 120 YTGCGGNDNNFVSREDCKRAC 140
Score = 96.3 bits (229), Expect = 1e-18
Identities = 48/140 (34%), Positives = 66/140 (47%), Gaps = 6/140 (4%)
Query: 1561 DGNGNRFATKEECDDVC--VQPSPKDACKLP-KVKGACVGYNVRWYYDSEREQCSQFVYG 1617
+GN N F T E CDD C ++ PK C+L V C G +++++ C +F G
Sbjct: 2 EGNANNFYTWEACDDACWRIEKVPK-VCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSG 60
Query: 1618 GCLGNA--NNFDTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIW 1675
GC N N F C C P + C P + G C+ N R+ FN + C+ F +
Sbjct: 61 GCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTY 120
Query: 1676 GGCEGNSNRFGSEAACKQRC 1695
GC GN N F S CK+ C
Sbjct: 121 TGCGGNDNNFVSREDCKRAC 140
Score = 92.3 bits (219), Expect = 2e-17
Identities = 44/142 (30%), Positives = 69/142 (48%), Gaps = 3/142 (2%)
Query: 1678 CEGNSNRFGSEAACKQRCDPPGTLQPRCS-QPREQGGCNETAAVWWFSPAEGRCRPFYYS 1736
CEGN+N F + AC C + C Q C + ++F+ + C F+
Sbjct: 1 CEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSG 60
Query: 1737 GCGGN--QNRFEDEAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
GC N +NRF DEA C C +P C P + G C+ +++++ + C F Y
Sbjct: 61 GCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTY 120
Query: 1795 GGCGGNENKFNSQIECESRCSE 1816
GCGGN+N F S+ +C+ C++
Sbjct: 121 TGCGGNDNNFVSREDCKRACAK 142
Score = 85.0 bits (201), Expect = 3e-15
Identities = 52/158 (32%), Positives = 71/158 (44%), Gaps = 22/158 (13%)
Query: 1738 CGGNQNRFEDEAACASSCPE-PFVPDLCTLPAETGE-CANYEEKWFYDTSEKRCRQFYYG 1795
C GN N F AC +C VP +C L + C EK+F++ S C +F+ G
Sbjct: 1 CEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSG 60
Query: 1796 GCGGN--ENKFNSQIECESRCSEIQXXXXXXXXXVQPQQPGPENSEFCFFETDPGPCTQF 1853
GC N EN+F + C C+ P++ FC+ D G C+
Sbjct: 61 GCHRNRIENRFPDEATCMGFCA--------------PKKI----PSFCYSPKDEGLCSAN 102
Query: 1854 ETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
TR+ ++ R C F Y GCGGN NNF S E C+ C
Sbjct: 103 VTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 140
Score = 67.3 bits (157), Expect = 6e-10
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 2/102 (1%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNG--NRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNV 1600
+++++ C +F+ GG N NRF + C C C PK +G C
Sbjct: 45 YFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVT 104
Query: 1601 RWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
R+Y++ C F Y GC GN NNF +RE C+ C A K
Sbjct: 105 RYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKK 146
Score = 66.1 bits (154), Expect = 1e-09
Identities = 31/103 (30%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 1850 CTQFETRWSYDARGGRCAPFQYGGCGGNT--NNFASEEHCQYYCHFTQ--DVCQLPMLAG 1905
C ++ ++ C F GGC N N F E C +C + C P G
Sbjct: 38 CEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEG 97
Query: 1906 PCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
C+ ++ ++++ C F Y GCGGNDN F SR++C+ C
Sbjct: 98 LCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRAC 140
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/76 (32%), Positives = 34/76 (44%)
Query: 2027 FQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRF 2086
F + C C K + C P D G C A + +YYF+ R+C F Y GC G N F
Sbjct: 71 FPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNF 130
Query: 2087 STIAECTEVCKNYIGK 2102
+ +C C + K
Sbjct: 131 VSREDCKRACAKALKK 146
Score = 54.0 bits (124), Expect = 6e-06
Identities = 44/159 (27%), Positives = 62/159 (38%), Gaps = 7/159 (4%)
Query: 1439 EGCGCHTYQFGCCPDGV-TISKGPGLQGCRCEQSQYGCCGDGETHATGPNLGGCDCSTSK 1497
EG + Y + C D I K P + CR + S C +G T NL C
Sbjct: 2 EGNANNFYTWEACDDACWRIEKVPKV--CRLQVSVDDQC-EGSTEKYFFNLSSMTCEKFF 58
Query: 1498 YGCCPDGQTLAEGPKFFGCTDIPENKQVA--CSLAKDRGSGRDYSVYWYYDMEYGGCSRF 1555
G C + P C K++ C KD G +Y++ Y C F
Sbjct: 59 SGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAF 118
Query: 1556 WYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGA 1594
Y G GN N F ++E+C C + K K+PK++ A
Sbjct: 119 TYTGCGGNDNNFVSREDCKRACAKALKKKK-KMPKLRFA 156
Score = 47.2 bits (107), Expect = 6e-04
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 4/78 (5%)
Query: 2023 NTGTFQTQEACERSCGAFKDI-NVCLYPLD-PGPCRAYLPKYYFDNERRSCQEFVYGGCH 2080
N F T EAC+ +C + + VC + C KY+F+ +C++F GGCH
Sbjct: 4 NANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCH 63
Query: 2081 GG--PNRFSTIAECTEVC 2096
NRF A C C
Sbjct: 64 RNRIENRFPDEATCMGFC 81
Score = 46.0 bits (104), Expect = 0.001
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 6/86 (6%)
Query: 1874 CGGNTNNFASEEHCQYYC---HFTQDVCQLPM-LAGPCNDSIVSWFYDASRDACSQFAYG 1929
C GN NNF + E C C VC+L + + C S +F++ S C +F G
Sbjct: 1 CEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSG 60
Query: 1930 GCGGN--DNRFASRDECESRCRSGRV 1953
GC N +NRF C C ++
Sbjct: 61 GCHRNRIENRFPDEATCMGFCAPKKI 86
>BT007425-1|AAP36093.1| 513|Homo sapiens serine protease inhibitor,
Kunitz type 1 protein.
Length = 513
Score = 96.3 bits (229), Expect = 1e-18
Identities = 62/202 (30%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
Query: 1627 DTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFG 1686
DT + + +T+D C + G C G+FPRW ++ Q C+ F++GGC GN N +
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 1687 SEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQN--R 1744
E C C G P S R C+ T F + G C + C N
Sbjct: 292 REEECILAC--RGVQGP--SMERRHPVCSGTCQPTQFRCSNGCCIDSFLE-CDDTPNCPD 346
Query: 1745 FEDEAAC---ASSCPE------PFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYG 1795
DEAAC S E P C +TG C +W+Y+ + C +F YG
Sbjct: 347 ASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYG 406
Query: 1796 GCGGNENKFNSQIECESRCSEI 1817
GC GN+N F + +C C I
Sbjct: 407 GCYGNKNNFEEEQQCLESCRGI 428
Score = 95.9 bits (228), Expect = 1e-18
Identities = 59/182 (32%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D C G C G RWYYD + C FVYGGCLGN NN+ E C C R
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC---RGV 303
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRC-EEFIWGGCEGNSNRFGSEAACKQRCDPPGTL 1701
S+ C+G F C + F+ N EAAC++ L
Sbjct: 304 QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDEL 363
Query: 1702 Q--------PRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
Q C + G C E+ W+++P C F Y GC GN+N FE+E C
Sbjct: 364 QRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLE 423
Query: 1754 SC 1755
SC
Sbjct: 424 SC 425
Score = 84.2 bits (199), Expect = 5e-15
Identities = 54/191 (28%), Positives = 75/191 (39%), Gaps = 15/191 (7%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C + G C +W+YD +E+ C+ F YGGC GN+N + + EC C +Q
Sbjct: 248 DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPS 307
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
V P F G C ++ D C T+ F
Sbjct: 308 MERRHPVCSGTCQPTQ-----FRCSNGCC--IDSFLECDDTPNCPDASDEAACEKYTSGF 360
Query: 1882 ASEEHCQYYCHFTQD---VCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRF 1938
+ HF D LP G C +SI W+Y+ + C++F YGGC GN N F
Sbjct: 361 DELQR----IHFPSDKGHCVDLPD-TGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNF 415
Query: 1939 ASRDECESRCR 1949
+C CR
Sbjct: 416 EEEQQCLESCR 426
Score = 67.7 bits (158), Expect = 4e-10
Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 17/181 (9%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQPSPKD 1584
C + G R WYYD C F YGG GN N + +EEC C VQ P
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ-GPSM 308
Query: 1585 ACKLPKVKGACVGYNVR----WYYDS-----EREQCSQFV-YGGCLGNANNFDTRELCQS 1634
+ P G C R DS + C C + FD +
Sbjct: 309 ERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHF 368
Query: 1635 QCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQR 1694
+ D LP + G C + PRW +N ++ C F +GGC GN N F E C +
Sbjct: 369 PSDKGHCVD---LP-DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLES 424
Query: 1695 C 1695
C
Sbjct: 425 C 425
Score = 59.7 bits (138), Expect = 1e-07
Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1580 PSPKDAC-KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEP 1638
PS K C LP G C RWYY+ E C++F YGGC GN NNF+ + C C
Sbjct: 369 PSDKGHCVDLPDT-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRG 427
Query: 1639 ARTKD 1643
KD
Sbjct: 428 ISKKD 432
Score = 57.6 bits (133), Expect = 4e-07
Identities = 22/56 (39%), Positives = 27/56 (48%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCR 1949
T+D C G C S W+YD + C F YGGC GN N + +EC CR
Sbjct: 246 TEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR 301
Score = 51.6 bits (118), Expect = 3e-05
Identities = 21/56 (37%), Positives = 28/56 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYIG 2101
CL G CR P++Y+D + C+ FVYGGC G N + EC C+ G
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQG 305
Score = 51.2 bits (117), Expect = 4e-05
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ ++C G C RW YD C F YGGC GN NN+ EE C C Q
Sbjct: 245 QTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ 304
Query: 1896 DVC---QLPMLAGPC 1907
+ P+ +G C
Sbjct: 305 GPSMERRHPVCSGTC 319
Score = 50.4 bits (115), Expect = 7e-05
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 9/77 (11%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPC---------RAYLPKYYFDNERRSCQEFVYGGCH 2080
+ ACE+ F ++ +P D G C + +P++Y++ C F YGGC+
Sbjct: 350 EAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCY 409
Query: 2081 GGPNRFSTIAECTEVCK 2097
G N F +C E C+
Sbjct: 410 GNKNNFEEEQQCLESCR 426
Score = 44.4 bits (100), Expect = 0.004
Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 1462 GLQGCRCEQSQYGCCGDGE-THATGPNLGGCDCSTSKYGC-----CPDGQTLAEGPKFFG 1515
G+QG E+ C G + T N GC C S C CPD A K+
Sbjct: 302 GVQGPSMERRHPVCSGTCQPTQFRCSN--GC-CIDSFLECDDTPNCPDASDEAACEKYTS 358
Query: 1516 CTD------IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFAT 1569
D P +K L D G ++ WYY+ C+RF YGG GN N F
Sbjct: 359 GFDELQRIHFPSDKGHCVDLP-DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEE 417
Query: 1570 KEECDDVCVQPSPKD 1584
+++C + C S KD
Sbjct: 418 EQQCLESCRGISKKD 432
>BC018702-1|AAH18702.1| 513|Homo sapiens serine peptidase inhibitor,
Kunitz type 1 protein.
Length = 513
Score = 96.3 bits (229), Expect = 1e-18
Identities = 62/202 (30%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
Query: 1627 DTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFG 1686
DT + + +T+D C + G C G+FPRW ++ Q C+ F++GGC GN N +
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 1687 SEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQN--R 1744
E C C G P S R C+ T F + G C + C N
Sbjct: 292 REEECILAC--RGVQGP--SMERRHPVCSGTCQPTQFRCSNGCCIDSFLE-CDDTPNCPD 346
Query: 1745 FEDEAAC---ASSCPE------PFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYG 1795
DEAAC S E P C +TG C +W+Y+ + C +F YG
Sbjct: 347 ASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYG 406
Query: 1796 GCGGNENKFNSQIECESRCSEI 1817
GC GN+N F + +C C I
Sbjct: 407 GCYGNKNNFEEEQQCLESCRGI 428
Score = 95.9 bits (228), Expect = 1e-18
Identities = 59/182 (32%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D C G C G RWYYD + C FVYGGCLGN NN+ E C C R
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC---RGV 303
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRC-EEFIWGGCEGNSNRFGSEAACKQRCDPPGTL 1701
S+ C+G F C + F+ N EAAC++ L
Sbjct: 304 QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDEL 363
Query: 1702 Q--------PRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
Q C + G C E+ W+++P C F Y GC GN+N FE+E C
Sbjct: 364 QRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLE 423
Query: 1754 SC 1755
SC
Sbjct: 424 SC 425
Score = 84.2 bits (199), Expect = 5e-15
Identities = 54/191 (28%), Positives = 75/191 (39%), Gaps = 15/191 (7%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C + G C +W+YD +E+ C+ F YGGC GN+N + + EC C +Q
Sbjct: 248 DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPS 307
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
V P F G C ++ D C T+ F
Sbjct: 308 MERRHPVCSGTCQPTQ-----FRCSNGCC--IDSFLECDDTPNCPDASDEAACEKYTSGF 360
Query: 1882 ASEEHCQYYCHFTQD---VCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRF 1938
+ HF D LP G C +SI W+Y+ + C++F YGGC GN N F
Sbjct: 361 DELQR----IHFPSDKGHCVDLPD-TGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNF 415
Query: 1939 ASRDECESRCR 1949
+C CR
Sbjct: 416 EEEQQCLESCR 426
Score = 67.7 bits (158), Expect = 4e-10
Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 17/181 (9%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQPSPKD 1584
C + G R WYYD C F YGG GN N + +EEC C VQ P
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ-GPSM 308
Query: 1585 ACKLPKVKGACVGYNVR----WYYDS-----EREQCSQFV-YGGCLGNANNFDTRELCQS 1634
+ P G C R DS + C C + FD +
Sbjct: 309 ERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHF 368
Query: 1635 QCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQR 1694
+ D LP + G C + PRW +N ++ C F +GGC GN N F E C +
Sbjct: 369 PSDKGHCVD---LP-DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLES 424
Query: 1695 C 1695
C
Sbjct: 425 C 425
Score = 59.7 bits (138), Expect = 1e-07
Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1580 PSPKDAC-KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEP 1638
PS K C LP G C RWYY+ E C++F YGGC GN NNF+ + C C
Sbjct: 369 PSDKGHCVDLPDT-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRG 427
Query: 1639 ARTKD 1643
KD
Sbjct: 428 ISKKD 432
Score = 57.6 bits (133), Expect = 4e-07
Identities = 22/56 (39%), Positives = 27/56 (48%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCR 1949
T+D C G C S W+YD + C F YGGC GN N + +EC CR
Sbjct: 246 TEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR 301
Score = 51.6 bits (118), Expect = 3e-05
Identities = 21/56 (37%), Positives = 28/56 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYIG 2101
CL G CR P++Y+D + C+ FVYGGC G N + EC C+ G
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQG 305
Score = 51.2 bits (117), Expect = 4e-05
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ ++C G C RW YD C F YGGC GN NN+ EE C C Q
Sbjct: 245 QTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ 304
Query: 1896 DVC---QLPMLAGPC 1907
+ P+ +G C
Sbjct: 305 GPSMERRHPVCSGTC 319
Score = 50.4 bits (115), Expect = 7e-05
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 9/77 (11%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPC---------RAYLPKYYFDNERRSCQEFVYGGCH 2080
+ ACE+ F ++ +P D G C + +P++Y++ C F YGGC+
Sbjct: 350 EAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCY 409
Query: 2081 GGPNRFSTIAECTEVCK 2097
G N F +C E C+
Sbjct: 410 GNKNNFEEEQQCLESCR 426
Score = 44.4 bits (100), Expect = 0.004
Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 1462 GLQGCRCEQSQYGCCGDGE-THATGPNLGGCDCSTSKYGC-----CPDGQTLAEGPKFFG 1515
G+QG E+ C G + T N GC C S C CPD A K+
Sbjct: 302 GVQGPSMERRHPVCSGTCQPTQFRCSN--GC-CIDSFLECDDTPNCPDASDEAACEKYTS 358
Query: 1516 CTD------IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFAT 1569
D P +K L D G ++ WYY+ C+RF YGG GN N F
Sbjct: 359 GFDELQRIHFPSDKGHCVDLP-DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEE 417
Query: 1570 KEECDDVCVQPSPKD 1584
+++C + C S KD
Sbjct: 418 EQQCLESCRGISKKD 432
>BC004140-1|AAH04140.1| 513|Homo sapiens serine peptidase inhibitor,
Kunitz type 1 protein.
Length = 513
Score = 96.3 bits (229), Expect = 1e-18
Identities = 62/202 (30%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
Query: 1627 DTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFG 1686
DT + + +T+D C + G C G+FPRW ++ Q C+ F++GGC GN N +
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 1687 SEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQN--R 1744
E C C G P S R C+ T F + G C + C N
Sbjct: 292 REEECILAC--RGVQGP--SMERRHPVCSGTCQPTQFRCSNGCCIDSFLE-CDDTPNCPD 346
Query: 1745 FEDEAAC---ASSCPE------PFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYG 1795
DEAAC S E P C +TG C +W+Y+ + C +F YG
Sbjct: 347 ASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYG 406
Query: 1796 GCGGNENKFNSQIECESRCSEI 1817
GC GN+N F + +C C I
Sbjct: 407 GCYGNKNNFEEEQQCLESCRGI 428
Score = 95.9 bits (228), Expect = 1e-18
Identities = 59/182 (32%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D C G C G RWYYD + C FVYGGCLGN NN+ E C C R
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC---RGV 303
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRC-EEFIWGGCEGNSNRFGSEAACKQRCDPPGTL 1701
S+ C+G F C + F+ N EAAC++ L
Sbjct: 304 QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDEL 363
Query: 1702 Q--------PRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
Q C + G C E+ W+++P C F Y GC GN+N FE+E C
Sbjct: 364 QRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLE 423
Query: 1754 SC 1755
SC
Sbjct: 424 SC 425
Score = 84.2 bits (199), Expect = 5e-15
Identities = 54/191 (28%), Positives = 75/191 (39%), Gaps = 15/191 (7%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C + G C +W+YD +E+ C+ F YGGC GN+N + + EC C +Q
Sbjct: 248 DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPS 307
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
V P F G C ++ D C T+ F
Sbjct: 308 MERRHPVCSGTCQPTQ-----FRCSNGCC--IDSFLECDDTPNCPDASDEAACEKYTSGF 360
Query: 1882 ASEEHCQYYCHFTQD---VCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRF 1938
+ HF D LP G C +SI W+Y+ + C++F YGGC GN N F
Sbjct: 361 DELQR----IHFPSDKGHCVDLPD-TGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNF 415
Query: 1939 ASRDECESRCR 1949
+C CR
Sbjct: 416 EEEQQCLESCR 426
Score = 67.7 bits (158), Expect = 4e-10
Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 17/181 (9%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQPSPKD 1584
C + G R WYYD C F YGG GN N + +EEC C VQ P
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ-GPSM 308
Query: 1585 ACKLPKVKGACVGYNVR----WYYDS-----EREQCSQFV-YGGCLGNANNFDTRELCQS 1634
+ P G C R DS + C C + FD +
Sbjct: 309 ERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHF 368
Query: 1635 QCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQR 1694
+ D LP + G C + PRW +N ++ C F +GGC GN N F E C +
Sbjct: 369 PSDKGHCVD---LP-DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLES 424
Query: 1695 C 1695
C
Sbjct: 425 C 425
Score = 59.7 bits (138), Expect = 1e-07
Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1580 PSPKDAC-KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEP 1638
PS K C LP G C RWYY+ E C++F YGGC GN NNF+ + C C
Sbjct: 369 PSDKGHCVDLPDT-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRG 427
Query: 1639 ARTKD 1643
KD
Sbjct: 428 ISKKD 432
Score = 57.6 bits (133), Expect = 4e-07
Identities = 22/56 (39%), Positives = 27/56 (48%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCR 1949
T+D C G C S W+YD + C F YGGC GN N + +EC CR
Sbjct: 246 TEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR 301
Score = 51.6 bits (118), Expect = 3e-05
Identities = 21/56 (37%), Positives = 28/56 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYIG 2101
CL G CR P++Y+D + C+ FVYGGC G N + EC C+ G
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQG 305
Score = 51.2 bits (117), Expect = 4e-05
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ ++C G C RW YD C F YGGC GN NN+ EE C C Q
Sbjct: 245 QTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ 304
Query: 1896 DVC---QLPMLAGPC 1907
+ P+ +G C
Sbjct: 305 GPSMERRHPVCSGTC 319
Score = 50.4 bits (115), Expect = 7e-05
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 9/77 (11%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPC---------RAYLPKYYFDNERRSCQEFVYGGCH 2080
+ ACE+ F ++ +P D G C + +P++Y++ C F YGGC+
Sbjct: 350 EAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCY 409
Query: 2081 GGPNRFSTIAECTEVCK 2097
G N F +C E C+
Sbjct: 410 GNKNNFEEEQQCLESCR 426
Score = 44.4 bits (100), Expect = 0.004
Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 1462 GLQGCRCEQSQYGCCGDGE-THATGPNLGGCDCSTSKYGC-----CPDGQTLAEGPKFFG 1515
G+QG E+ C G + T N GC C S C CPD A K+
Sbjct: 302 GVQGPSMERRHPVCSGTCQPTQFRCSN--GC-CIDSFLECDDTPNCPDASDEAACEKYTS 358
Query: 1516 CTD------IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFAT 1569
D P +K L D G ++ WYY+ C+RF YGG GN N F
Sbjct: 359 GFDELQRIHFPSDKGHCVDLP-DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEE 417
Query: 1570 KEECDDVCVQPSPKD 1584
+++C + C S KD
Sbjct: 418 EQQCLESCRGISKKD 432
>AB000095-1|BAA25014.1| 513|Homo sapiens hepatocyte growth factor
activator inhibitor protein.
Length = 513
Score = 96.3 bits (229), Expect = 1e-18
Identities = 62/202 (30%), Positives = 86/202 (42%), Gaps = 16/202 (7%)
Query: 1627 DTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFG 1686
DT + + +T+D C + G C G+FPRW ++ Q C+ F++GGC GN N +
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 1687 SEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQN--R 1744
E C C G P S R C+ T F + G C + C N
Sbjct: 292 REEECILAC--RGVQGP--SMERRHPVCSGTCQPTQFRCSNGCCIDSFLE-CDDTPNCPD 346
Query: 1745 FEDEAAC---ASSCPE------PFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYG 1795
DEAAC S E P C +TG C +W+Y+ + C +F YG
Sbjct: 347 ASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYG 406
Query: 1796 GCGGNENKFNSQIECESRCSEI 1817
GC GN+N F + +C C I
Sbjct: 407 GCYGNKNNFEEEQQCLESCRGI 428
Score = 95.9 bits (228), Expect = 1e-18
Identities = 59/182 (32%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
+D C G C G RWYYD + C FVYGGCLGN NN+ E C C R
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC---RGV 303
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRC-EEFIWGGCEGNSNRFGSEAACKQRCDPPGTL 1701
S+ C+G F C + F+ N EAAC++ L
Sbjct: 304 QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDEL 363
Query: 1702 Q--------PRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACAS 1753
Q C + G C E+ W+++P C F Y GC GN+N FE+E C
Sbjct: 364 QRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLE 423
Query: 1754 SC 1755
SC
Sbjct: 424 SC 425
Score = 84.2 bits (199), Expect = 5e-15
Identities = 54/191 (28%), Positives = 75/191 (39%), Gaps = 15/191 (7%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C + G C +W+YD +E+ C+ F YGGC GN+N + + EC C +Q
Sbjct: 248 DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPS 307
Query: 1822 XXXXXXVQPQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNF 1881
V P F G C ++ D C T+ F
Sbjct: 308 MERRHPVCSGTCQPTQ-----FRCSNGCC--IDSFLECDDTPNCPDASDEAACEKYTSGF 360
Query: 1882 ASEEHCQYYCHFTQD---VCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRF 1938
+ HF D LP G C +SI W+Y+ + C++F YGGC GN N F
Sbjct: 361 DELQR----IHFPSDKGHCVDLPD-TGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNF 415
Query: 1939 ASRDECESRCR 1949
+C CR
Sbjct: 416 EEEQQCLESCR 426
Score = 67.7 bits (158), Expect = 4e-10
Identities = 53/181 (29%), Positives = 68/181 (37%), Gaps = 17/181 (9%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQPSPKD 1584
C + G R WYYD C F YGG GN N + +EEC C VQ P
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ-GPSM 308
Query: 1585 ACKLPKVKGACVGYNVR----WYYDS-----EREQCSQFV-YGGCLGNANNFDTRELCQS 1634
+ P G C R DS + C C + FD +
Sbjct: 309 ERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHF 368
Query: 1635 QCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQR 1694
+ D LP + G C + PRW +N ++ C F +GGC GN N F E C +
Sbjct: 369 PSDKGHCVD---LP-DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLES 424
Query: 1695 C 1695
C
Sbjct: 425 C 425
Score = 59.7 bits (138), Expect = 1e-07
Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1580 PSPKDAC-KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEP 1638
PS K C LP G C RWYY+ E C++F YGGC GN NNF+ + C C
Sbjct: 369 PSDKGHCVDLPDT-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRG 427
Query: 1639 ARTKD 1643
KD
Sbjct: 428 ISKKD 432
Score = 57.6 bits (133), Expect = 4e-07
Identities = 22/56 (39%), Positives = 27/56 (48%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCR 1949
T+D C G C S W+YD + C F YGGC GN N + +EC CR
Sbjct: 246 TEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR 301
Score = 51.6 bits (118), Expect = 3e-05
Identities = 21/56 (37%), Positives = 28/56 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYIG 2101
CL G CR P++Y+D + C+ FVYGGC G N + EC C+ G
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQG 305
Score = 51.2 bits (117), Expect = 4e-05
Identities = 25/75 (33%), Positives = 32/75 (42%), Gaps = 3/75 (4%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ ++C G C RW YD C F YGGC GN NN+ EE C C Q
Sbjct: 245 QTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ 304
Query: 1896 DVC---QLPMLAGPC 1907
+ P+ +G C
Sbjct: 305 GPSMERRHPVCSGTC 319
Score = 50.4 bits (115), Expect = 7e-05
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 9/77 (11%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPC---------RAYLPKYYFDNERRSCQEFVYGGCH 2080
+ ACE+ F ++ +P D G C + +P++Y++ C F YGGC+
Sbjct: 350 EAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCY 409
Query: 2081 GGPNRFSTIAECTEVCK 2097
G N F +C E C+
Sbjct: 410 GNKNNFEEEQQCLESCR 426
Score = 44.4 bits (100), Expect = 0.004
Identities = 42/135 (31%), Positives = 55/135 (40%), Gaps = 16/135 (11%)
Query: 1462 GLQGCRCEQSQYGCCGDGE-THATGPNLGGCDCSTSKYGC-----CPDGQTLAEGPKFFG 1515
G+QG E+ C G + T N GC C S C CPD A K+
Sbjct: 302 GVQGPSMERRHPVCSGTCQPTQFRCSN--GC-CIDSFLECDDTPNCPDASDEAACEKYTS 358
Query: 1516 CTD------IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFAT 1569
D P +K L D G ++ WYY+ C+RF YGG GN N F
Sbjct: 359 GFDELQRIHFPSDKGHCVDLP-DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEE 417
Query: 1570 KEECDDVCVQPSPKD 1584
+++C + C S KD
Sbjct: 418 EQQCLESCRGISKKD 432
>AK131196-1|BAD18391.1| 283|Homo sapiens protein ( Homo sapiens cDNA
FLJ16032 fis, clone NTONG2003316, weakly similar to AMBP
PROTEIN PRECURSOR. ).
Length = 283
Score = 92.7 bits (220), Expect = 1e-17
Identities = 40/99 (40%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
Query: 1614 FVYGGCLGNANNFDTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEF 1673
F +G C N N+F+T E C C CSLP +G C PRW +N +T +C+ F
Sbjct: 63 FTFGHCHRNLNHFETYEACMLACMSGPLA-ACSLPALQGPCKAYAPRWAYNSQTGQCQSF 121
Query: 1674 IWGGCEGNSNRFGSEAACKQRCD-PPGTLQPRCSQPREQ 1711
++GGCEGN N F S AC++ C P G + R +PR++
Sbjct: 122 VYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQK 160
Score = 91.1 bits (216), Expect = 4e-17
Identities = 44/109 (40%), Positives = 55/109 (50%), Gaps = 1/109 (0%)
Query: 1555 FWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQF 1614
F +G N N F T E C C+ P AC LP ++G C Y RW Y+S+ QC F
Sbjct: 63 FTFGHCHRNLNHFETYEACMLACMS-GPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSF 121
Query: 1615 VYGGCLGNANNFDTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGF 1663
VYGGC GN NNF++RE C+ C R +C R +F R F
Sbjct: 122 VYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDF 170
Score = 75.4 bits (177), Expect = 2e-12
Identities = 33/81 (40%), Positives = 39/81 (48%), Gaps = 1/81 (1%)
Query: 1869 FQYGGCGGNTNNFASEEHCQYYCHFTQ-DVCQLPMLAGPCNDSIVSWFYDASRDACSQFA 1927
F +G C N N+F + E C C C LP L GPC W Y++ C F
Sbjct: 63 FTFGHCHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFV 122
Query: 1928 YGGCGGNDNRFASRDECESRC 1948
YGGC GN N F SR+ CE C
Sbjct: 123 YGGCEGNGNNFESREACEESC 143
Score = 72.5 bits (170), Expect = 1e-11
Identities = 36/86 (41%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 1673 FIWGGCEGNSNRFGSEAACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRP 1732
F +G C N N F + AC C G L CS P QG C A W ++ G+C+
Sbjct: 63 FTFGHCHRNLNHFETYEACMLAC-MSGPLAA-CSLPALQGPCKAYAPRWAYNSQTGQCQS 120
Query: 1733 FYYSGCGGNQNRFEDEAACASSCPEP 1758
F Y GC GN N FE AC SCP P
Sbjct: 121 FVYGGCEGNGNNFESREACEESCPFP 146
Score = 71.7 bits (168), Expect = 3e-11
Identities = 32/82 (39%), Positives = 42/82 (51%), Gaps = 1/82 (1%)
Query: 1733 FYYSGCGGNQNRFEDEAACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQF 1792
F + C N N FE AC +C + C+LPA G C Y +W Y++ +C+ F
Sbjct: 63 FTFGHCHRNLNHFETYEACMLACMSGPLA-ACSLPALQGPCKAYAPRWAYNSQTGQCQSF 121
Query: 1793 YYGGCGGNENKFNSQIECESRC 1814
YGGC GN N F S+ CE C
Sbjct: 122 VYGGCEGNGNNFESREACEESC 143
Score = 70.9 bits (166), Expect = 5e-11
Identities = 30/75 (40%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
Query: 2022 RNTGTFQTQEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHG 2081
RN F+T EAC +C + + C P GPC+AY P++ ++++ CQ FVYGGC G
Sbjct: 70 RNLNHFETYEACMLACMS-GPLAACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEG 128
Query: 2082 GPNRFSTIAECTEVC 2096
N F + C E C
Sbjct: 129 NGNNFESREACEESC 143
Score = 62.5 bits (145), Expect = 2e-08
Identities = 24/53 (45%), Positives = 31/53 (58%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHF 1893
C GPC + RW+Y+++ G+C F YGGC GN NNF S E C+ C F
Sbjct: 93 CSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPF 145
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/65 (38%), Positives = 36/65 (55%)
Query: 1526 ACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDA 1585
ACSL +G + Y+ W Y+ + G C F YGG +GNGN F ++E C++ C P
Sbjct: 92 ACSLPALQGPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQR 151
Query: 1586 CKLPK 1590
C+ K
Sbjct: 152 CRACK 156
>AY358969-1|AAQ89328.1| 529|Homo sapiens HAI-1 protein.
Length = 529
Score = 91.5 bits (217), Expect = 3e-17
Identities = 63/195 (32%), Positives = 80/195 (41%), Gaps = 22/195 (11%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE----- 1637
+D C G C G RWYYD + C FVYGGCLGN NN+ E C C
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGG 306
Query: 1638 PARTKD--QCSLP----IERGS--CAGNFPRWGFNDETQRC-EEFIWGGCEGNSNRFGSE 1688
P R Q + P +ER C+G F C + F+ N E
Sbjct: 307 PLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDE 366
Query: 1689 AACKQRCDPPGTLQ--------PRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGG 1740
AAC++ LQ C + G C E+ W+++P C F Y GC G
Sbjct: 367 AACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYG 426
Query: 1741 NQNRFEDEAACASSC 1755
N+N FE+E C SC
Sbjct: 427 NKNNFEEEQQCLESC 441
Score = 90.2 bits (214), Expect = 7e-17
Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 27/205 (13%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C + G C +W+YD +E+ C+ F YGGC GN+N + + EC C +Q
Sbjct: 248 DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGGP 307
Query: 1822 XXXXXXVQ---PQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNT 1878
Q PQ P E G C + R S C + C
Sbjct: 308 LRGSSGAQATFPQGPSMERRH----PVCSGTCQPTQFRCS-----NGCCIDSFLECDDTP 358
Query: 1879 N--NFASEEHCQYY---------CHFTQD---VCQLPMLAGPCNDSIVSWFYDASRDACS 1924
N + + E C+ Y HF D LP G C +SI W+Y+ + C+
Sbjct: 359 NCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPD-TGLCKESIPRWYYNPFSEHCA 417
Query: 1925 QFAYGGCGGNDNRFASRDECESRCR 1949
+F YGGC GN N F +C CR
Sbjct: 418 RFTYGGCYGNKNNFEEEQQCLESCR 442
Score = 88.6 bits (210), Expect = 2e-16
Identities = 61/214 (28%), Positives = 85/214 (39%), Gaps = 24/214 (11%)
Query: 1627 DTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFG 1686
DT + + +T+D C + G C G+FPRW ++ Q C+ F++GGC GN N +
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 1687 SEAACKQRC------------DPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFY 1734
E C C T S R C+ T F + G C +
Sbjct: 292 REEECILACRGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSF 351
Query: 1735 YSGCGGNQN--RFEDEAAC---ASSCPE------PFVPDLCTLPAETGECANYEEKWFYD 1783
C N DEAAC S E P C +TG C +W+Y+
Sbjct: 352 LE-CDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYN 410
Query: 1784 TSEKRCRQFYYGGCGGNENKFNSQIECESRCSEI 1817
+ C +F YGGC GN+N F + +C C I
Sbjct: 411 PFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 444
Score = 83.8 bits (198), Expect = 6e-15
Identities = 56/213 (26%), Positives = 77/213 (36%), Gaps = 25/213 (11%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRV 1953
T+D C G C S W+YD + C F YGGC GN N + +EC CR G
Sbjct: 246 TEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR-GVQ 304
Query: 1954 AEVSXXXXXXXXXXXXXXXXXXXESRFRGECEVSPTLERCVAPGLVWYLDAARRECVVHS 2013
G C+ PT RC C + S
Sbjct: 305 GGPLRGSSGAQATFPQGPSMERRHPVCSGTCQ--PTQFRC------------SNGCCIDS 350
Query: 2014 NAESGLTCRNTGTFQTQEACERSCGAFKDINVCLYPLDPGP---------CRAYLPKYYF 2064
E T N + ACE+ F ++ +P D G C+ +P++Y+
Sbjct: 351 FLECDDT-PNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYY 409
Query: 2065 DNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
+ C F YGGC+G N F +C E C+
Sbjct: 410 NPFSEHCARFTYGGCYGNKNNFEEEQQCLESCR 442
Score = 59.7 bits (138), Expect = 1e-07
Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1580 PSPKDAC-KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEP 1638
PS K C LP G C RWYY+ E C++F YGGC GN NNF+ + C C
Sbjct: 385 PSDKGHCVDLPDT-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRG 443
Query: 1639 ARTKD 1643
KD
Sbjct: 444 ISKKD 448
Score = 59.3 bits (137), Expect = 1e-07
Identities = 52/192 (27%), Positives = 70/192 (36%), Gaps = 23/192 (11%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQPSP-K 1583
C + G R WYYD C F YGG GN N + +EEC C VQ P +
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGGPLR 309
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQF--VYGGCLGNANNFDTRELCQSQCEPART 1641
+ R S Q +QF G C+ + D C + A
Sbjct: 310 GSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 369
Query: 1642 KDQCS---------LPIERGSCAG---------NFPRWGFNDETQRCEEFIWGGCEGNSN 1683
+ S P ++G C + PRW +N ++ C F +GGC GN N
Sbjct: 370 EKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKN 429
Query: 1684 RFGSEAACKQRC 1695
F E C + C
Sbjct: 430 NFEEEQQCLESC 441
Score = 51.6 bits (118), Expect = 3e-05
Identities = 21/56 (37%), Positives = 28/56 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYIG 2101
CL G CR P++Y+D + C+ FVYGGC G N + EC C+ G
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQG 305
Score = 50.8 bits (116), Expect = 5e-05
Identities = 22/60 (36%), Positives = 26/60 (43%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ ++C G C RW YD C F YGGC GN NN+ EE C C Q
Sbjct: 245 QTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ 304
Score = 43.6 bits (98), Expect = 0.008
Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 7/90 (7%)
Query: 1501 CPDGQTLAEGPKFFGCTD------IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSR 1554
CPD A K+ D P +K L D G ++ WYY+ C+R
Sbjct: 360 CPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLP-DTGLCKESIPRWYYNPFSEHCAR 418
Query: 1555 FWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
F YGG GN N F +++C + C S KD
Sbjct: 419 FTYGGCYGNKNNFEEEQQCLESCRGISKKD 448
>AY296715-1|AAP44001.1| 529|Homo sapiens hepatocyte growth factor
activator inhibitor 1B protein.
Length = 529
Score = 91.5 bits (217), Expect = 3e-17
Identities = 63/195 (32%), Positives = 80/195 (41%), Gaps = 22/195 (11%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE----- 1637
+D C G C G RWYYD + C FVYGGCLGN NN+ E C C
Sbjct: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGG 306
Query: 1638 PARTKD--QCSLP----IERGS--CAGNFPRWGFNDETQRC-EEFIWGGCEGNSNRFGSE 1688
P R Q + P +ER C+G F C + F+ N E
Sbjct: 307 PLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDE 366
Query: 1689 AACKQRCDPPGTLQ--------PRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGG 1740
AAC++ LQ C + G C E+ W+++P C F Y GC G
Sbjct: 367 AACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYG 426
Query: 1741 NQNRFEDEAACASSC 1755
N+N FE+E C SC
Sbjct: 427 NKNNFEEEQQCLESC 441
Score = 90.2 bits (214), Expect = 7e-17
Identities = 60/205 (29%), Positives = 82/205 (40%), Gaps = 27/205 (13%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQXXX 1821
D C + G C +W+YD +E+ C+ F YGGC GN+N + + EC C +Q
Sbjct: 248 DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGGP 307
Query: 1822 XXXXXXVQ---PQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNT 1878
Q PQ P E G C + R S C + C
Sbjct: 308 LRGSSGAQATFPQGPSMERRH----PVCSGTCQPTQFRCS-----NGCCIDSFLECDDTP 358
Query: 1879 N--NFASEEHCQYY---------CHFTQD---VCQLPMLAGPCNDSIVSWFYDASRDACS 1924
N + + E C+ Y HF D LP G C +SI W+Y+ + C+
Sbjct: 359 NCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPD-TGLCKESIPRWYYNPFSEHCA 417
Query: 1925 QFAYGGCGGNDNRFASRDECESRCR 1949
+F YGGC GN N F +C CR
Sbjct: 418 RFTYGGCYGNKNNFEEEQQCLESCR 442
Score = 88.6 bits (210), Expect = 2e-16
Identities = 61/214 (28%), Positives = 85/214 (39%), Gaps = 24/214 (11%)
Query: 1627 DTRELCQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFG 1686
DT + + +T+D C + G C G+FPRW ++ Q C+ F++GGC GN N +
Sbjct: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
Query: 1687 SEAACKQRC------------DPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFY 1734
E C C T S R C+ T F + G C +
Sbjct: 292 REEECILACRGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSF 351
Query: 1735 YSGCGGNQN--RFEDEAAC---ASSCPE------PFVPDLCTLPAETGECANYEEKWFYD 1783
C N DEAAC S E P C +TG C +W+Y+
Sbjct: 352 LE-CDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYN 410
Query: 1784 TSEKRCRQFYYGGCGGNENKFNSQIECESRCSEI 1817
+ C +F YGGC GN+N F + +C C I
Sbjct: 411 PFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 444
Score = 83.8 bits (198), Expect = 6e-15
Identities = 56/213 (26%), Positives = 77/213 (36%), Gaps = 25/213 (11%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGRV 1953
T+D C G C S W+YD + C F YGGC GN N + +EC CR G
Sbjct: 246 TEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACR-GVQ 304
Query: 1954 AEVSXXXXXXXXXXXXXXXXXXXESRFRGECEVSPTLERCVAPGLVWYLDAARRECVVHS 2013
G C+ PT RC C + S
Sbjct: 305 GGPLRGSSGAQATFPQGPSMERRHPVCSGTCQ--PTQFRC------------SNGCCIDS 350
Query: 2014 NAESGLTCRNTGTFQTQEACERSCGAFKDINVCLYPLDPGP---------CRAYLPKYYF 2064
E T N + ACE+ F ++ +P D G C+ +P++Y+
Sbjct: 351 FLECDDT-PNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYY 409
Query: 2065 DNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
+ C F YGGC+G N F +C E C+
Sbjct: 410 NPFSEHCARFTYGGCYGNKNNFEEEQQCLESCR 442
Score = 59.7 bits (138), Expect = 1e-07
Identities = 28/65 (43%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 1580 PSPKDAC-KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEP 1638
PS K C LP G C RWYY+ E C++F YGGC GN NNF+ + C C
Sbjct: 385 PSDKGHCVDLPDT-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRG 443
Query: 1639 ARTKD 1643
KD
Sbjct: 444 ISKKD 448
Score = 59.3 bits (137), Expect = 1e-07
Identities = 52/192 (27%), Positives = 70/192 (36%), Gaps = 23/192 (11%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC--VQPSP-K 1583
C + G R WYYD C F YGG GN N + +EEC C VQ P +
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGGPLR 309
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQF--VYGGCLGNANNFDTRELCQSQCEPART 1641
+ R S Q +QF G C+ + D C + A
Sbjct: 310 GSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 369
Query: 1642 KDQCS---------LPIERGSCAG---------NFPRWGFNDETQRCEEFIWGGCEGNSN 1683
+ S P ++G C + PRW +N ++ C F +GGC GN N
Sbjct: 370 EKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKN 429
Query: 1684 RFGSEAACKQRC 1695
F E C + C
Sbjct: 430 NFEEEQQCLESC 441
Score = 51.6 bits (118), Expect = 3e-05
Identities = 21/56 (37%), Positives = 28/56 (50%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYIG 2101
CL G CR P++Y+D + C+ FVYGGC G N + EC C+ G
Sbjct: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQG 305
Score = 50.8 bits (116), Expect = 5e-05
Identities = 22/60 (36%), Positives = 26/60 (43%)
Query: 1836 ENSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQ 1895
+ ++C G C RW YD C F YGGC GN NN+ EE C C Q
Sbjct: 245 QTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQ 304
Score = 43.6 bits (98), Expect = 0.008
Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 7/90 (7%)
Query: 1501 CPDGQTLAEGPKFFGCTD------IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSR 1554
CPD A K+ D P +K L D G ++ WYY+ C+R
Sbjct: 360 CPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLP-DTGLCKESIPRWYYNPFSEHCAR 418
Query: 1555 FWYGGSDGNGNRFATKEECDDVCVQPSPKD 1584
F YGG GN N F +++C + C S KD
Sbjct: 419 FTYGGCYGNKNNFEEEQQCLESCRGISKKD 448
>AF027205-1|AAB84031.1| 252|Homo sapiens Kunitz-type protease
inhibitor protein.
Length = 252
Score = 90.2 bits (214), Expect = 7e-17
Identities = 48/164 (29%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C KW+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPKWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPKWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 74.5 bits (175), Expect = 4e-12
Identities = 46/172 (26%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C +W+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPKWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPKWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 54.0 bits (124), Expect = 6e-06
Identities = 23/51 (45%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +PK++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPKWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>U78095-1|AAC02781.1| 252|Homo sapiens bikunin protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>CR407604-1|CAG28532.1| 252|Homo sapiens SPINT2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>BT020117-1|AAV38920.1| 252|Homo sapiens serine protease inhibitor,
Kunitz type, 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>BT020116-1|AAV38919.1| 252|Homo sapiens serine protease inhibitor,
Kunitz type, 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>BT020115-1|AAV38918.1| 252|Homo sapiens serine protease inhibitor,
Kunitz type, 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>BC012868-1|AAH12868.1| 252|Homo sapiens serine peptidase inhibitor,
Kunitz type, 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>BC011955-1|AAH11955.1| 252|Homo sapiens serine peptidase inhibitor,
Kunitz type, 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>BC011951-1|AAH11951.1| 252|Homo sapiens serine peptidase inhibitor,
Kunitz type, 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>BC007705-1|AAH07705.1| 252|Homo sapiens serine peptidase inhibitor,
Kunitz type, 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>BC001668-1|AAH01668.1| 252|Homo sapiens serine peptidase inhibitor,
Kunitz type, 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>AB006534-1|BAA25024.1| 252|Homo sapiens hepatocyte growth factor
activator inhibitor type 2 protein.
Length = 252
Score = 89.0 bits (211), Expect = 2e-16
Identities = 47/164 (28%), Positives = 70/164 (42%), Gaps = 18/164 (10%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSE 1816
E + D C + G C +W+Y+ ++ C+ F YGGC GN N + ++ EC +C+
Sbjct: 31 ERSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCAT 90
Query: 1817 IQXXXXXXXXXVQ-------PQQPGPENSE-----------FCFFETDPGPCTQFETRWS 1858
+ + P P ++SE +C GPC RW
Sbjct: 91 VTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWY 150
Query: 1859 YDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQLPM 1902
+D C F YGGC GN N++ SEE C C Q+ LP+
Sbjct: 151 FDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPL 194
Score = 81.8 bits (193), Expect = 2e-14
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 23/169 (13%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDAC 1586
C ++K G R W+Y++ G C F YGG DGN N + TKEEC C +
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATG 97
Query: 1587 KLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKDQCS 1646
L + A + R Q S+ +++ F+ E C +
Sbjct: 98 DLATSRNAADSS----VPSAPRRQDSED------HSSDMFNYEEYCTANA---------- 137
Query: 1647 LPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
G C +FPRW F+ E C FI+GGC GN N + SE AC RC
Sbjct: 138 ---VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 75.8 bits (178), Expect = 2e-12
Identities = 47/172 (27%), Positives = 66/172 (38%), Gaps = 24/172 (13%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTKD 1643
D C + KV G C RW+Y+ C FVYGGC GN+NN+ T+E C +C
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDPPGTLQP 1703
L R + + P +++ + +S+ F E C
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSE----------DHSSDMFNYEEYCTANA-------- 137
Query: 1704 RCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G C + W+F C F Y GC GN+N + E AC C
Sbjct: 138 ------VTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 63.3 bits (147), Expect = 9e-09
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 1883 SEEHCQYYCHFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRD 1942
SE+H ++ ++ C + GPC S W++D R++C+ F YGGC GN N + S +
Sbjct: 119 SEDHSSDMFNY-EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEE 177
Query: 1943 ECESRC 1948
C RC
Sbjct: 178 ACMLRC 183
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/151 (23%), Positives = 59/151 (39%), Gaps = 12/151 (7%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS---GR 1952
D C + + G C S+ W+Y+ + +C F YGGC GN N + +++EC +C +
Sbjct: 36 DFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENA 95
Query: 1953 VAEVSXXXXXXXXXXXXXXXXXXXES------RFRGECEVSPTLERCVAPGLVWYLDAAR 2006
+++ E + C + C A WY D R
Sbjct: 96 TGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVER 155
Query: 2007 RECVVHSNAESGLTCRNTGTFQTQEACERSC 2037
C +N G N +++++EAC C
Sbjct: 156 NSC---NNFIYGGCRGNKNSYRSEEACMLRC 183
Score = 60.5 bits (140), Expect = 6e-08
Identities = 26/67 (38%), Positives = 34/67 (50%)
Query: 2030 QEACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTI 2089
Q++ + S F C GPCRA P++YFD ER SC F+YGGC G N + +
Sbjct: 117 QDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSE 176
Query: 2090 AECTEVC 2096
C C
Sbjct: 177 EACMLRC 183
Score = 60.1 bits (139), Expect = 8e-08
Identities = 25/67 (37%), Positives = 37/67 (55%), Gaps = 2/67 (2%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C V G C RWY+D ER C+ F+YGGC GN N++ + E C +C R +
Sbjct: 130 EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRC--FRQQ 187
Query: 1643 DQCSLPI 1649
+ LP+
Sbjct: 188 ENPPLPL 194
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/51 (43%), Positives = 30/51 (58%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL G CRA +P+++++ SCQ FVYGGC G N + T EC + C
Sbjct: 38 CLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKC 88
Score = 41.5 bits (93), Expect = 0.032
Identities = 18/52 (34%), Positives = 26/52 (50%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
N + C+ G R WY+D+E C+ F YGG GN N + ++E C
Sbjct: 128 NYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEAC 179
>AL353895-4|CAI14853.2| 470|Homo sapiens ADAMTS-like 1 protein.
Length = 470
Score = 87.0 bits (206), Expect = 6e-16
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 27/190 (14%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVT-KDYRVVNSSFCSYHPT-----PALEEPCDKDKL 565
W +++ C TC + A+C + RVV +C Y+P P L+E C+ D
Sbjct: 88 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQE-CNLDPC 146
Query: 566 PAC----QV----------QWYATQWSKCSVECGVGKKTRRVFCGKFD-GASVMKVDDSN 610
PA Q+ +W AT W+ CS CG G ++R V C + D V V++
Sbjct: 147 PASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWK 206
Query: 611 CPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPK 669
C K ++PC + + CP KW A WS CT +CG+GLR+R V+C+ G C
Sbjct: 207 CMYTPKMPIAQPCNIFD--CP-KWLAQEWSPCTVTCGQGLRYRVVLCIDHRGMHTGGCSP 263
Query: 670 KSLPDSAGSC 679
K+ P C
Sbjct: 264 KTKPHIKEEC 273
Score = 86.6 bits (205), Expect = 8e-16
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 25/169 (14%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATN-QTCNTQA 384
+ W +F CSATCGGG Q C VV + C + +KP Q CN
Sbjct: 86 HRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDP 145
Query: 385 CP-----------------PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDD 427
CP P+W W+ CS CG G +SR V C + G + V++
Sbjct: 146 CPASDGYKQIMPYDLYHPLPRWEATPWTACSSSCG-GGIQSRAVSCVEEDIQGHVTSVEE 204
Query: 428 KECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVC 476
+C + PK + + CN+ CP W W PC CG G + R V+C
Sbjct: 205 WKC--MYTPKMPIAQPCNI-FDCPKWLAQEWSPCTVTCGQGLRYRVVLC 250
Score = 85.0 bits (201), Expect = 3e-15
Identities = 102/398 (25%), Positives = 160/398 (40%), Gaps = 90/398 (22%)
Query: 369 DDGLKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
+ G +T Q Q +W ++ CS CG G + C + +N VV D+
Sbjct: 68 NSGSADSTVQFIFYQPIIHRWRETDFFPCSATCG-GGYQLTSAECYDLRSN---RVVADQ 123
Query: 429 ECF---DLLGPKPALYESCNVDAA-----------------CPTWFISPWKPCDKLCGSG 468
C + + PKP L E CN+D P W +PW C CG G
Sbjct: 124 YCHYYPENIKPKPKLQE-CNLDPCPASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGG 182
Query: 469 QQTRQVVCYQKN-NGRINVLSDDEC--SEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TC 524
Q+R V C +++ G + + + +C + + P+ QPC + C W+ EW+ C TC
Sbjct: 183 IQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPI-AQPCNIFDCP--KWLAQEWSPCTVTC 239
Query: 525 LATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC--------DKDKLPA-CQVQWY-- 573
+R RV C+ D+R +++ CS P ++E C K+KLP ++ W+
Sbjct: 240 GQGLRYRVVLCI--DHRGMHTGGCSPKTKPHIKEECIVPTPCYKPKEKLPVEAKLPWFKQ 297
Query: 574 -----------------ATQWSKCSVECGVGKKTRRVFCGKF----DGASVMKVDDSNCP 612
WS C+V CGVG + R V C + + +D+ P
Sbjct: 298 AQELEEGAAVSEEPSFIPEAWSACTVTCGVGTQVRIVRCQVLLSFSQSVADLPIDECEGP 357
Query: 613 K--EEKYNDSKPC--EVPEEKCPS---------------KWYAAPWSECTKSCGKGLRFR 653
K ++ + PC E+PE W +++C++SCG G++
Sbjct: 358 KPASQRACYAGPCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEA 417
Query: 654 SVVCL----RGGKEFSDC-PKKSLPDSAGSCNEQSCEA 686
V CL R E + C + P SCN C A
Sbjct: 418 VVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPA 455
Score = 76.2 bits (179), Expect = 1e-12
Identities = 81/308 (26%), Positives = 121/308 (39%), Gaps = 58/308 (18%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSRE---ELEVVDEGLCDDGLKPATNQTCNTQACPP 387
W +++CS++CGGGIQSR V+C + + V+E C K Q CN C P
Sbjct: 167 WEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPIAQPCNIFDC-P 225
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRC---EKIITNGL-----PSVVDD----------KE 429
+W+ WS C+ CG+ G R R V C + T G P + ++ KE
Sbjct: 226 KWLAQEWSPCTVTCGQ-GLRYRVVLCIDHRGMHTGGCSPKTKPHIKEECIVPTPCYKPKE 284
Query: 430 CFDLLGPKPALYESCNVDAAC-----PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRI 484
+ P ++ ++ P++ W C CG G Q R V C +
Sbjct: 285 KLPVEAKLPWFKQAQELEEGAAVSEEPSFIPEAWSACTVTCGVGTQVRIVRCQVLLSFSQ 344
Query: 485 NV--LSDDECSEEKPLDRQPCELEPCEG-----------------------VDWMVSEWT 519
+V L DEC KP ++ C PC G DW +T
Sbjct: 345 SVADLPIDECEGPKPASQRACYAGPCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFT 404
Query: 520 GC-DTCLATVRSRVAQCVTKDYR-VVNSSFC-SYHPTPALEEPCDKDKLPACQVQWYATQ 576
C ++C V+ V C+ K R + C + P L + C+ D PA +
Sbjct: 405 KCSESCGGGVQEAVVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPARSS--IDSA 462
Query: 577 WSKCSVEC 584
W+ C+V C
Sbjct: 463 WNACNVLC 470
Score = 58.0 bits (134), Expect = 3e-07
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPP 387
Y W + F+ CS +CGGG+Q V+C +++ E +E LC + P ++CN CP
Sbjct: 396 YDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPA 455
Query: 388 Q-WVPGNWSRCSKRC 401
+ + W+ C+ C
Sbjct: 456 RSSIDSAWNACNVLC 470
Score = 41.1 bits (92), Expect = 0.042
Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 35/182 (19%)
Query: 313 YEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREEL--EVVDEGLCD- 369
++ + +E+ ++ S++ +S+C+ TCG G Q R V C+ V D + +
Sbjct: 295 FKQAQELEEGAAVSEEPSFIPEAWSACTVTCGVGTQVRIVRCQVLLSFSQSVADLPIDEC 354
Query: 370 DGLKPATNQTCNTQACP---PQWVPG----------------NW-----SRCSKRCGKDG 405
+G KPA+ + C C P++ P +W ++CS+ CG G
Sbjct: 355 EGPKPASQRACYAGPCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFTKCSESCG-GG 413
Query: 406 TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP--TWFISPWKPCDK 463
+ V C + ++ C P P L +SCN+D CP + S W C+
Sbjct: 414 VQEAVVSC---LNKQTREPAEENLCVTSRRP-PQLLKSCNLD-PCPARSSIDSAWNACNV 468
Query: 464 LC 465
LC
Sbjct: 469 LC 470
>AF251058-1|AAK34948.1| 417|Homo sapiens thrombospondin protein.
Length = 417
Score = 87.0 bits (206), Expect = 6e-16
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 27/190 (14%)
Query: 513 WMVSEWTGCD-TCLATVRSRVAQCVT-KDYRVVNSSFCSYHPT-----PALEEPCDKDKL 565
W +++ C TC + A+C + RVV +C Y+P P L+E C+ D
Sbjct: 35 WRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQE-CNLDPC 93
Query: 566 PAC----QV----------QWYATQWSKCSVECGVGKKTRRVFCGKFD-GASVMKVDDSN 610
PA Q+ +W AT W+ CS CG G ++R V C + D V V++
Sbjct: 94 PASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWK 153
Query: 611 CPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCL-RGGKEFSDCPK 669
C K ++PC + + CP KW A WS CT +CG+GLR+R V+C+ G C
Sbjct: 154 CMYTPKMPIAQPCNIFD--CP-KWLAQEWSPCTVTCGQGLRYRVVLCIDHRGMHTGGCSP 210
Query: 670 KSLPDSAGSC 679
K+ P C
Sbjct: 211 KTKPHIKEEC 220
Score = 86.6 bits (205), Expect = 8e-16
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 25/169 (14%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATN-QTCNTQA 384
+ W +F CSATCGGG Q C VV + C + +KP Q CN
Sbjct: 33 HRWRETDFFPCSATCGGGYQLTSAECYDLRSNRVVADQYCHYYPENIKPKPKLQECNLDP 92
Query: 385 CP-----------------PQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDD 427
CP P+W W+ CS CG G +SR V C + G + V++
Sbjct: 93 CPASDGYKQIMPYDLYHPLPRWEATPWTACSSSCG-GGIQSRAVSCVEEDIQGHVTSVEE 151
Query: 428 KECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVC 476
+C + PK + + CN+ CP W W PC CG G + R V+C
Sbjct: 152 WKC--MYTPKMPIAQPCNI-FDCPKWLAQEWSPCTVTCGQGLRYRVVLC 197
Score = 85.0 bits (201), Expect = 3e-15
Identities = 102/398 (25%), Positives = 160/398 (40%), Gaps = 90/398 (22%)
Query: 369 DDGLKPATNQTCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDK 428
+ G +T Q Q +W ++ CS CG G + C + +N VV D+
Sbjct: 15 NSGSADSTVQFIFYQPIIHRWRETDFFPCSATCG-GGYQLTSAECYDLRSN---RVVADQ 70
Query: 429 ECF---DLLGPKPALYESCNVDAA-----------------CPTWFISPWKPCDKLCGSG 468
C + + PKP L E CN+D P W +PW C CG G
Sbjct: 71 YCHYYPENIKPKPKLQE-CNLDPCPASDGYKQIMPYDLYHPLPRWEATPWTACSSSCGGG 129
Query: 469 QQTRQVVCYQKN-NGRINVLSDDEC--SEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TC 524
Q+R V C +++ G + + + +C + + P+ QPC + C W+ EW+ C TC
Sbjct: 130 IQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPI-AQPCNIFDCP--KWLAQEWSPCTVTC 186
Query: 525 LATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC--------DKDKLPA-CQVQWY-- 573
+R RV C+ D+R +++ CS P ++E C K+KLP ++ W+
Sbjct: 187 GQGLRYRVVLCI--DHRGMHTGGCSPKTKPHIKEECIVPTPCYKPKEKLPVEAKLPWFKQ 244
Query: 574 -----------------ATQWSKCSVECGVGKKTRRVFCGKF----DGASVMKVDDSNCP 612
WS C+V CGVG + R V C + + +D+ P
Sbjct: 245 AQELEEGAAVSEEPSFIPEAWSACTVTCGVGTQVRIVRCQVLLSFSQSVADLPIDECEGP 304
Query: 613 K--EEKYNDSKPC--EVPEEKCPS---------------KWYAAPWSECTKSCGKGLRFR 653
K ++ + PC E+PE W +++C++SCG G++
Sbjct: 305 KPASQRACYAGPCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFTKCSESCGGGVQEA 364
Query: 654 SVVCL----RGGKEFSDC-PKKSLPDSAGSCNEQSCEA 686
V CL R E + C + P SCN C A
Sbjct: 365 VVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPA 402
Score = 76.2 bits (179), Expect = 1e-12
Identities = 81/308 (26%), Positives = 121/308 (39%), Gaps = 58/308 (18%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSRE---ELEVVDEGLCDDGLKPATNQTCNTQACPP 387
W +++CS++CGGGIQSR V+C + + V+E C K Q CN C P
Sbjct: 114 WEATPWTACSSSCGGGIQSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPIAQPCNIFDC-P 172
Query: 388 QWVPGNWSRCSKRCGKDGTRSREVRC---EKIITNGL-----PSVVDD----------KE 429
+W+ WS C+ CG+ G R R V C + T G P + ++ KE
Sbjct: 173 KWLAQEWSPCTVTCGQ-GLRYRVVLCIDHRGMHTGGCSPKTKPHIKEECIVPTPCYKPKE 231
Query: 430 CFDLLGPKPALYESCNVDAAC-----PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRI 484
+ P ++ ++ P++ W C CG G Q R V C +
Sbjct: 232 KLPVEAKLPWFKQAQELEEGAAVSEEPSFIPEAWSACTVTCGVGTQVRIVRCQVLLSFSQ 291
Query: 485 NV--LSDDECSEEKPLDRQPCELEPCEG-----------------------VDWMVSEWT 519
+V L DEC KP ++ C PC G DW +T
Sbjct: 292 SVADLPIDECEGPKPASQRACYAGPCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFT 351
Query: 520 GC-DTCLATVRSRVAQCVTKDYR-VVNSSFC-SYHPTPALEEPCDKDKLPACQVQWYATQ 576
C ++C V+ V C+ K R + C + P L + C+ D PA +
Sbjct: 352 KCSESCGGGVQEAVVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPARSS--IDSA 409
Query: 577 WSKCSVEC 584
W+ C+V C
Sbjct: 410 WNACNVLC 417
Score = 58.0 bits (134), Expect = 3e-07
Identities = 24/75 (32%), Positives = 40/75 (53%), Gaps = 2/75 (2%)
Query: 329 YSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLK-PATNQTCNTQACPP 387
Y W + F+ CS +CGGG+Q V+C +++ E +E LC + P ++CN CP
Sbjct: 343 YDWEYEGFTKCSESCGGGVQEAVVSCLNKQTREPAEENLCVTSRRPPQLLKSCNLDPCPA 402
Query: 388 Q-WVPGNWSRCSKRC 401
+ + W+ C+ C
Sbjct: 403 RSSIDSAWNACNVLC 417
Score = 41.1 bits (92), Expect = 0.042
Identities = 45/182 (24%), Positives = 77/182 (42%), Gaps = 35/182 (19%)
Query: 313 YEYSLPIEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREEL--EVVDEGLCD- 369
++ + +E+ ++ S++ +S+C+ TCG G Q R V C+ V D + +
Sbjct: 242 FKQAQELEEGAAVSEEPSFIPEAWSACTVTCGVGTQVRIVRCQVLLSFSQSVADLPIDEC 301
Query: 370 DGLKPATNQTCNTQACP---PQWVPG----------------NW-----SRCSKRCGKDG 405
+G KPA+ + C C P++ P +W ++CS+ CG G
Sbjct: 302 EGPKPASQRACYAGPCSGEIPEFNPDETDGLFGGLQDFDELYDWEYEGFTKCSESCG-GG 360
Query: 406 TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP--TWFISPWKPCDK 463
+ V C + ++ C P P L +SCN+D CP + S W C+
Sbjct: 361 VQEAVVSC---LNKQTREPAEENLCVTSRRP-PQLLKSCNLD-PCPARSSIDSAWNACNV 415
Query: 464 LC 465
LC
Sbjct: 416 LC 417
>AB051466-1|BAB21770.1| 1536|Homo sapiens KIAA1679 protein protein.
Length = 1536
Score = 87.0 bits (206), Expect = 6e-16
Identities = 88/347 (25%), Positives = 143/347 (41%), Gaps = 44/347 (12%)
Query: 335 NFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQT--CNTQACPPQWVPG 392
++ SCS++CG G++ R + + D + ++ C ++ WV
Sbjct: 936 SWGSCSSSCGIGVRIRSKWLKEKPYNGGRPCPKLDLKNQAQVHEAVPCYSECNQYSWVVE 995
Query: 393 NWSRC-------SKRCGKDGTRSREVRCEKIITNGLPSVVDDKEC-FDLLGPK-PALYES 443
+WS C S RCG GT+SR++RC +G VD C D + P+ +
Sbjct: 996 HWSSCKINNELRSLRCG-GGTQSRKIRCVN-TADGEGGAVDSNLCNQDEIPPETQSCSLM 1053
Query: 444 CNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPC 503
C + W + W C + C R+ + + L+ C+E+ + QPC
Sbjct: 1054 CPNECVMSEWGL--WSKCPQSCDPHTMQRRTRHLLRPS-----LNSRTCAEDSQV--QPC 1104
Query: 504 EL-EPCEGVDWMVSEWTGCD-----TCLATVRSRVAQCVTKDYRVVNSSFCSYH---PTP 554
L E C + ++EW+ C C VR+R+ CV D + V+ C H
Sbjct: 1105 LLNENCFQFQYNLTEWSTCQLSENAPCGQGVRTRLLSCVCSDGKPVSMDQCEQHNLEKPQ 1164
Query: 555 ALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKE 614
+ PC + + CQ+ + T W++CS CG G + R +F +M P
Sbjct: 1165 RMSIPCLVECVVNCQLSGW-TAWTECSQTCGHGGRMSRT---RF---IIMPTQGEGRPCP 1217
Query: 615 EKYNDSKPCEVPEEKCPSKWYAAPWSECT---KSCGKGLRFRSVVCL 658
+ K C P C S W WS C CG+G++ RS+ C+
Sbjct: 1218 TELTQEKTC--PVTPCYS-WVLGNWSACKLEGGDCGEGVQIRSLSCM 1261
Score = 85.4 bits (202), Expect = 2e-15
Identities = 96/360 (26%), Positives = 150/360 (41%), Gaps = 55/360 (15%)
Query: 328 RYSWVHGNFSSC-------SATCGGGIQSRDVTCRSREELE--VVDEGLCDDGLKPATNQ 378
+YSWV ++SSC S CGGG QSR + C + + E VD LC+ P Q
Sbjct: 989 QYSWVVEHWSSCKINNELRSLRCGGGTQSRKIRCVNTADGEGGAVDSNLCNQDEIPPETQ 1048
Query: 379 TCNTQACPPQWVP---GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLG 435
+C+ CP + V G WS+C + C T R R + L ++ + C +
Sbjct: 1049 SCSLM-CPNECVMSEWGLWSKCPQSCDPH-TMQRRTR------HLLRPSLNSRTCAEDSQ 1100
Query: 436 PKPALYESCNVDAACPTWFISPWKPC----DKLCGSGQQTRQVVCYQKNNGRINVLSDDE 491
+P L N + + ++ W C + CG G +TR + C + +++ ++
Sbjct: 1101 VQPCL---LNENCFQFQYNLTEWSTCQLSENAPCGQGVRTRLLSCVCSDGKPVSMDQCEQ 1157
Query: 492 CSEEKPLDRQ-PCELEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSY 550
+ EKP PC +E C V+ +S WT C +Q R+ + F
Sbjct: 1158 HNLEKPQRMSIPCLVE-CV-VNCQLSGWTAWTEC--------SQTCGHGGRMSRTRFI-I 1206
Query: 551 HPTPALEEPCDKD--KLPACQV----QWYATQWSKCSVE---CGVGKKTRRVFCGKFDGA 601
PT PC + + C V W WS C +E CG G + R + C G+
Sbjct: 1207 MPTQGEGRPCPTELTQEKTCPVTPCYSWVLGNWSACKLEGGDCGEGVQIRSLSCMVHSGS 1266
Query: 602 ---SVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSE---CTKSCGKGLRFRSV 655
+ +V+D+ C E + DS ++ CP + WSE C +C G F +V
Sbjct: 1267 ISHAAGRVEDALC-GEMPFQDSILKQLCSVPCPGDCHLTEWSEWSTCELTCIDGRSFETV 1325
Score = 84.2 bits (199), Expect = 5e-15
Identities = 100/374 (26%), Positives = 148/374 (39%), Gaps = 73/374 (19%)
Query: 343 CGGGIQSRDVTC----------RSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
CGGGIQ+R+V C R++E V++ LC G P +Q CN C +
Sbjct: 359 CGGGIQTREVYCAQSVPAAAALRAKEVSRPVEKALC-VGPAPLPSQLCNI-PCSTDCIVS 416
Query: 393 NWS--------RCSKRCGKDG--TRSREVRCEKIITNG-LPSVVDDKECFDLLGPKPALY 441
+WS C + GK G TR R V E G P +V+ C D P Y
Sbjct: 417 SWSAWGLCIHENCHEPQGKKGFRTRQRHVLMESTGPAGHCPHLVESVPCED-----PMCY 471
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
+ C P CG G + + VC N R +S C P +R+
Sbjct: 472 RWLASEGIC--------FPDHGKCGLGHRILKAVC---QNDRGEDVSGSLCPVPPPPERK 520
Query: 502 PCELEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVV----NSSFCSYHPTPALE 557
CE+ PC +D ++SEWT +C + ++ + R + P+ AL+
Sbjct: 521 SCEI-PCR-MDCVLSEWTEWSSCSQSCSNKNSDGKQTRSRTILALAGEGGKPCPPSQALQ 578
Query: 558 EPCDKDKLPACQVQWYATQWSKCSVE-----------------CGVGKKTRRVFCGKFDG 600
E + Q+ W + W CS + CGVG +TRRVFC K
Sbjct: 579 EHRLCNDHSCMQLHWETSPWGPCSEDTLVTALNATIGWNGEATCGVGIQTRRVFCVK--- 635
Query: 601 ASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG------LRFRS 654
+ V +V CP + +PC +P +K + W+ C + C G R+R
Sbjct: 636 SHVGQVMTKRCPDSTRPETVRPCFLPCKKDCIVTAFSEWTPCPRMCQAGNATVKQSRYRI 695
Query: 655 VV--CLRGGKEFSD 666
++ GG+E D
Sbjct: 696 IIQEAANGGQECPD 709
Score = 79.4 bits (187), Expect = 1e-13
Identities = 87/331 (26%), Positives = 131/331 (39%), Gaps = 35/331 (10%)
Query: 340 SATCGGGIQSRDVTCRSREELEVVDEGLCDDG--LKPATNQTCNTQACPPQWVPGNWSRC 397
S CG G++ R V C + VD C ++ C W +W C
Sbjct: 884 SKECGEGLRFRAVACSDKNG-RPVDPSFCSSSGYIQEKCVIPCPFDCKLSDW--SSWGSC 940
Query: 398 SKRCGKDGTRSREVRC-EKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFIS 456
S CG G R R EK G P D + + Y CN + W +
Sbjct: 941 SSSCGI-GVRIRSKWLKEKPYNGGRPCPKLDLKNQAQVHEAVPCYSECNQYS----WVVE 995
Query: 457 PWKPC---DKL----CGSGQQTRQVVCYQKNNGRINVLSDDECSEEK-PLDRQPCELEPC 508
W C ++L CG G Q+R++ C +G + + C++++ P + Q C L C
Sbjct: 996 HWSSCKINNELRSLRCGGGTQSRKIRCVNTADGEGGAVDSNLCNQDEIPPETQSCSL-MC 1054
Query: 509 EGVDWMVSEWTGCDTCLATVRSRVAQCVTKDY--RVVNSSFCSYHPTPALEEPCDKDKLP 566
+ ++SEW C + Q T+ +NS C+ + +PC ++
Sbjct: 1055 PN-ECVMSEWGLWSKCPQSCDPHTMQRRTRHLLRPSLNSRTCA---EDSQVQPCLLNE-N 1109
Query: 567 ACQVQWYATQWSKCSVE----CGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP 622
Q Q+ T+WS C + CG G +TR + C DG V E+ S P
Sbjct: 1110 CFQFQYNLTEWSTCQLSENAPCGQGVRTRLLSCVCSDGKPVSMDQCEQHNLEKPQRMSIP 1169
Query: 623 CEVP-EEKCP-SKWYAAPWSECTKSCGKGLR 651
C V C S W A W+EC+++CG G R
Sbjct: 1170 CLVECVVNCQLSGWTA--WTECSQTCGHGGR 1198
Score = 77.0 bits (181), Expect = 7e-13
Identities = 107/390 (27%), Positives = 151/390 (38%), Gaps = 72/390 (18%)
Query: 346 GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACPP-QWVPGNWSRCSKRCGK 403
G Q+R V+C +R + + LC P T Q+C + C QW +WS CSK C
Sbjct: 226 GYQTRQVSC-TRSDGQNAMLSLCLQDSFPLTVQSCIMPKDCETSQW--SSWSPCSKTCRS 282
Query: 404 D----GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP--TWFISP 457
G RSR + + G KEC +LL + + E + CP +W S
Sbjct: 283 GSLLPGFRSRSRNVKHMAIGG------GKECPELLEKEACIVEG-ELLQQCPRYSWRTSE 335
Query: 458 WKPCD----------------KLCGSGQQTRQVVCYQKNNGRINVLSDDE--------CS 493
WK C +CG G QTR+V C Q + + + C
Sbjct: 336 WKECQVSLLLEQQDPHWHVTGPVCGGGIQTREVYCAQSVPAAAALRAKEVSRPVEKALCV 395
Query: 494 EEKPLDRQPCELEPCEGVDWMVSEWTGCDTCL---ATVRSRVAQCVTKDYRVVNSSFCSY 550
PL Q C + PC D +VS W+ C+ T+ V+ S
Sbjct: 396 GPAPLPSQLCNI-PC-STDCIVSSWSAWGLCIHENCHEPQGKKGFRTRQRHVLMESTGPA 453
Query: 551 HPTPALEE--PCDKDKLPACQVQWYATQWSKCSVE---CGVGKKTRRVFCGKFDGASVMK 605
P L E PC+ P C +W A++ C + CG+G + + C G
Sbjct: 454 GHCPHLVESVPCED---PMC-YRWLASE-GICFPDHGKCGLGHRILKAVCQNDRGED--- 505
Query: 606 VDDSNCPKEEKYNDSKPCEVP-EEKCP-SKWYAAPWSECTKSC------GKGLRFRSVVC 657
V S CP + K CE+P C S+W WS C++SC GK R R+++
Sbjct: 506 VSGSLCPVPPP-PERKSCEIPCRMDCVLSEW--TEWSSCSQSCSNKNSDGKQTRSRTILA 562
Query: 658 LRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
L G+ CP CN+ SC L
Sbjct: 563 L-AGEGGKPCPPSQALQEHRLCNDHSCMQL 591
Score = 74.9 bits (176), Expect = 3e-12
Identities = 97/375 (25%), Positives = 137/375 (36%), Gaps = 58/375 (15%)
Query: 341 ATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVP---GNWSRC 397
ATCG GIQ+R V C +V+ + C D +P T + C C + W+ C
Sbjct: 620 ATCGVGIQTRRVFCVKSHVGQVMTKR-CPDSTRPETVRPCFLP-CKKDCIVTAFSEWTPC 677
Query: 398 SKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPT--WFI 455
+ C ++ R II +EC D L + C + CP W
Sbjct: 678 PRMCQAGNATVKQSRYRIIIQEAANG---GQECPDTLYEE----RECEDVSLCPVYRWKP 730
Query: 456 SPWKPC--------------DKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
W PC + CG G QTR V C +N ++ + + PL Q
Sbjct: 731 QKWSPCILVPESVWQGITGSSEACGKGLQTRAVSCISDDNRSAEMMECLKQTNGMPLLVQ 790
Query: 502 PCEL---EPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEE 558
C + E C W S++T C T +SR Q K + +P E
Sbjct: 791 ECTVPCREDCTFTAW--SKFTPCSTNCEATKSRRRQLTGKSRKKEKCQDSDLYPLVETEL 848
Query: 559 -PCDKDK-----------LPACQVQWY-ATQWSKCSVECGVGKKTRRVFCGKFDGASVMK 605
PCD+ LP + + + + S ECG G + R V C +G V
Sbjct: 849 CPCDEFISQPYGNWSDCILPEGRREPHRGLRVQADSKECGEGLRFRAVACSDKNGRPV-- 906
Query: 606 VDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC----LRGG 661
D S C + P + S W + W C+ SCG G+R RS GG
Sbjct: 907 -DPSFCSSSGYIQEKCVIPCPFDCKLSDW--SSWGSCSSSCGIGVRIRSKWLKEKPYNGG 963
Query: 662 KEFSDCPKKSLPDSA 676
+ CPK L + A
Sbjct: 964 R---PCPKLDLKNQA 975
Score = 66.9 bits (156), Expect = 7e-10
Identities = 98/374 (26%), Positives = 146/374 (39%), Gaps = 65/374 (17%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEG--LCDDGLKPATNQTCNTQACPP-QWVPG 392
+SSCS +C T RSR L + EG C ++ CN +C W
Sbjct: 538 WSSCSQSCSNKNSDGKQT-RSRTILALAGEGGKPCPPSQALQEHRLCNDHSCMQLHWETS 596
Query: 393 NWSRCSK-----------------RCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLG 435
W CS+ CG G ++R V C K + + K C D
Sbjct: 597 PWGPCSEDTLVTALNATIGWNGEATCGV-GIQTRRVFCVKSHVGQVMT----KRCPDSTR 651
Query: 436 PKPA--LYESCNVDAACPTWFISPWKPCDKLCGSG----QQTRQVVCYQK--NNGRI--- 484
P+ + C D C S W PC ++C +G +Q+R + Q+ N G+
Sbjct: 652 PETVRPCFLPCKKD--CIVTAFSEWTPCPRMCQAGNATVKQSRYRIIIQEAANGGQECPD 709
Query: 485 NVLSDDECSEEK--PLDR-QPCELEPCEGVDWMVSEW-TGC-DTCLATVRSRVAQCVTKD 539
+ + EC + P+ R +P + PC V V + TG + C +++R C++ D
Sbjct: 710 TLYEERECEDVSLCPVYRWKPQKWSPCILVPESVWQGITGSSEACGKGLQTRAVSCISDD 769
Query: 540 YRVVNSSFC--SYHPTPALEEPCDKDKLPACQVQWYATQWSK---CSVECGVGKKTRRVF 594
R C + P L + C +P C+ T WSK CS C K RR
Sbjct: 770 NRSAEMMECLKQTNGMPLLVQECT---VP-CREDCTFTAWSKFTPCSTNCEATKSRRRQL 825
Query: 595 CGKF-------DGASVMKVDDSNCPKEE----KYNDSKPCEVPEEKCPSKWYAAPWSECT 643
GK D V+ CP +E Y + C +PE + ++ +
Sbjct: 826 TGKSRKKEKCQDSDLYPLVETELCPCDEFISQPYGNWSDCILPEGRREPHRGLRVQAD-S 884
Query: 644 KSCGKGLRFRSVVC 657
K CG+GLRFR+V C
Sbjct: 885 KECGEGLRFRAVAC 898
Score = 47.6 bits (108), Expect = 5e-04
Identities = 69/285 (24%), Positives = 108/285 (37%), Gaps = 46/285 (16%)
Query: 340 SATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQT--CNTQACPPQWVPG--NWS 395
+A CG G+++R ++C + V + L+ + C + + G W+
Sbjct: 1128 NAPCGQGVRTRLLSCVCSDGKPVSMDQCEQHNLEKPQRMSIPCLVECVVNCQLSGWTAWT 1187
Query: 396 RCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
CS+ CG G S R II +P+ + + C P E C +W +
Sbjct: 1188 ECSQTCGHGGRMS---RTRFII---MPTQGEGRPC-----PTELTQEKTCPVTPCYSWVL 1236
Query: 456 SPWKPCDKL----CGSGQQTRQVVCYQKNN------GRINVLSDDECSEEKPLDRQPCEL 505
W C KL CG G Q R + C + GR+ E + + +Q C +
Sbjct: 1237 GNWSAC-KLEGGDCGEGVQIRSLSCMVHSGSISHAAGRVEDALCGEMPFQDSILKQLCSV 1295
Query: 506 EPCEGVDWMVSEWTGCDTC-LATVRSRVAQCVTKDYRVVNSSFCSYH-----PTPALE-E 558
PC G D ++EW+ TC L + R + V + R S+ P LE
Sbjct: 1296 -PCPG-DCHLTEWSEWSTCELTCIDGRSFETVGRQSRSRTFIIQSFENQDSCPQQVLETR 1353
Query: 559 PCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASV 603
PC K W A+ W+ R V+C + DG +V
Sbjct: 1354 PCTGGK--CYHYTWKASLWN---------NNERTVWCQRSDGVNV 1387
Score = 41.1 bits (92), Expect = 0.042
Identities = 74/314 (23%), Positives = 103/314 (32%), Gaps = 42/314 (13%)
Query: 342 TCGGGIQSRDVTCRSREELEVVDEGLCDD-GLKPATNQTCNTQACPPQWVPGN---WSRC 397
T G+Q R V C + VV +C+ L+P T Q C CP V WS C
Sbjct: 61 TAQHGLQHRMVRCIQKLNRTVVANEICEHFALQPPTEQACLIP-CPRDCVVSEFLPWSNC 119
Query: 398 SKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISP 457
SK CGK + R +I P + +C P +C+ +CP
Sbjct: 120 SKGCGK----KLQHRTRAVIA---PPLFGGLQC-----PNLTESRACDAPISCPLG--EE 165
Query: 458 WKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSE 517
G + R + N VL + S E+ + W +
Sbjct: 166 EYTFSLKVGPWSKCRLPHLKEINPSGRTVLDFNSDSNERVTFKHQSYKAHHHSKSWAIE- 224
Query: 518 WTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQV-QWYATQ 576
G T R C D + S C P + C K C+ QW +
Sbjct: 225 -IGYQT-------RQVSCTRSDGQNAMLSLCLQDSFPLTVQSCIMPK--DCETSQW--SS 272
Query: 577 WSKCSVECGVGKKTRRVFCGKFDGASVMKV-DDSNCPKEEKYNDSKPCEVPEE---KCPS 632
WS CS C G F + M + CP + + + C V E +CP
Sbjct: 273 WSPCSKTCRSGSLLPG-FRSRSRNVKHMAIGGGKECP---ELLEKEACIVEGELLQQCPR 328
Query: 633 -KWYAAPWSECTKS 645
W + W EC S
Sbjct: 329 YSWRTSEWKECQVS 342
Score = 39.9 bits (89), Expect = 0.096
Identities = 43/170 (25%), Positives = 62/170 (36%), Gaps = 19/170 (11%)
Query: 518 WTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
W G TC +++R CV V + C P PC C V ++ +W
Sbjct: 616 WNGEATCGVGIQTRRVFCVKSHVGQVMTKRCPDSTRPETVRPCFLPCKKDCIVTAFS-EW 674
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP----KEEKYNDSKPCEVPEEKCPSK 633
+ C C G T + + CP +E + D C V K P K
Sbjct: 675 TPCPRMCQAGNATVKQSRYRIIIQEAAN-GGQECPDTLYEERECEDVSLCPVYRWK-PQK 732
Query: 634 WYA------APWSECTKS---CGKGLRFRSVVCL---RGGKEFSDCPKKS 671
W + W T S CGKGL+ R+V C+ E +C K++
Sbjct: 733 WSPCILVPESVWQGITGSSEACGKGLQTRAVSCISDDNRSAEMMECLKQT 782
Score = 37.1 bits (82), Expect = 0.68
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 16/96 (16%)
Query: 320 EKAPLPTQRYSWVHGNFSSC---SATCGGGIQSRDVTCRSR-----EELEVVDEGLC--- 368
EK T YSWV GN+S+C CG G+Q R ++C V++ LC
Sbjct: 1223 EKTCPVTPCYSWVLGNWSACKLEGGDCGEGVQIRSLSCMVHSGSISHAAGRVEDALCGEM 1282
Query: 369 ---DDGLKPATNQTCNTQACPPQWVPGNWSRCSKRC 401
D LK + C +W WS C C
Sbjct: 1283 PFQDSILKQLCSVPCPGDCHLTEW--SEWSTCELTC 1316
Score = 36.7 bits (81), Expect = 0.90
Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 586 VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKS 645
+G +TR+V C + DG + M S C ++ + C +P++ S+W + WS C+K+
Sbjct: 225 IGYQTRQVSCTRSDGQNAML---SLCLQDSFPLTVQSCIMPKDCETSQW--SSWSPCSKT 279
Query: 646 CGKG 649
C G
Sbjct: 280 CRSG 283
Score = 35.5 bits (78), Expect = 2.1
Identities = 32/128 (25%), Positives = 52/128 (40%), Gaps = 13/128 (10%)
Query: 521 CDTCLATVRSRVAQCVTKDYR-VVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQ--- 576
C T ++ R+ +C+ K R VV + C + AL+ P ++ L C ++
Sbjct: 59 CVTAQHGLQHRMVRCIQKLNRTVVANEICEHF---ALQPPTEQACLIPCPRDCVVSEFLP 115
Query: 577 WSKCSVECG--VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
WS CS CG + +TR V G + N + + C + EE+
Sbjct: 116 WSNCSKGCGKKLQHRTRAVIAPPLFGG----LQCPNLTESRACDAPISCPLGEEEYTFSL 171
Query: 635 YAAPWSEC 642
PWS+C
Sbjct: 172 KVGPWSKC 179
>BC033125-1|AAH33125.1| 740|Homo sapiens THSD7B protein protein.
Length = 740
Score = 83.4 bits (197), Expect = 8e-15
Identities = 100/374 (26%), Positives = 147/374 (39%), Gaps = 73/374 (19%)
Query: 343 CGGGIQSRDVTC----------RSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
CGGGIQ+R+V C R++E V++ LC G P +Q CN C +
Sbjct: 178 CGGGIQTREVYCAQSVPAAAALRAKEVSRPVEKALC-VGPAPLPSQLCNI-PCSTDCIVS 235
Query: 393 NWS--------RCSKRCGKDG--TRSREVRCEKIITNG-LPSVVDDKECFDLLGPKPALY 441
+WS C GK G TR R V E G P +V+ C D P Y
Sbjct: 236 SWSAWGLCIHENCHDPQGKKGFRTRQRHVLMESTGPAGHCPHLVESVPCED-----PMCY 290
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
+ C P CG G + + VC N R +S C P +R+
Sbjct: 291 RWLASEGIC--------FPDHGKCGLGHRILKAVC---QNDRGEDVSGSLCPVPPPPERK 339
Query: 502 PCELEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVV----NSSFCSYHPTPALE 557
CE+ PC +D ++SEWT +C + ++ + R + P+ AL+
Sbjct: 340 SCEI-PCR-MDCVLSEWTEWSSCSQSCSNKNSDGKQTRSRTILALAGEGGKPCPPSQALQ 397
Query: 558 EPCDKDKLPACQVQWYATQWSKCSVE-----------------CGVGKKTRRVFCGKFDG 600
E + Q+ W + W CS + CGVG +TRRVFC K
Sbjct: 398 EHRLCNDHSCMQLHWETSPWGPCSEDTLVTALNATIGWNGEATCGVGIQTRRVFCVK--- 454
Query: 601 ASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG------LRFRS 654
+ V +V CP + +PC +P +K + W+ C + C G R+R
Sbjct: 455 SHVGQVMTKRCPDSTRPETVRPCFLPCKKDCIVTAFSEWTPCPRMCQAGNATVKQSRYRI 514
Query: 655 VV--CLRGGKEFSD 666
++ GG+E D
Sbjct: 515 IIQEAANGGQECPD 528
Score = 77.0 bits (181), Expect = 7e-13
Identities = 104/390 (26%), Positives = 155/390 (39%), Gaps = 72/390 (18%)
Query: 346 GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACPP-QWVPGNWSRCSKRCGK 403
G Q+R V+C +R + + LC P T Q+C + C QW +WS CSK C
Sbjct: 45 GYQTRQVSC-TRSDGQNAMLSLCLQDSFPLTVQSCIMPKDCETSQW--SSWSPCSKTCRS 101
Query: 404 D----GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP--TWFISP 457
G RSR + + G KEC +LL + + E + CP +W S
Sbjct: 102 GSLLPGFRSRSRNVKHMAIGG------GKECPELLEKEACIVEG-ELLQQCPRYSWRTSE 154
Query: 458 WKPCD----------------KLCGSGQQTRQVVCYQKNNGRINVLSDDE--------CS 493
WK C +CG G QTR+V C Q + + + C
Sbjct: 155 WKECQVSLLLEQQDPHWHVTGPVCGGGIQTREVYCAQSVPAAAALRAKEVSRPVEKALCV 214
Query: 494 EEKPLDRQPCELEPCEGVDWMVSEWTGCDTCL----ATVRSRVAQCVTKDYRVVNSSFCS 549
PL Q C + PC D +VS W+ C+ + + + + ++ S+ +
Sbjct: 215 GPAPLPSQLCNI-PC-STDCIVSSWSAWGLCIHENCHDPQGKKGFRTRQRHVLMESTGPA 272
Query: 550 YHPTPALEE-PCDKDKLPACQVQWYATQWSKCSVE---CGVGKKTRRVFCGKFDGASVMK 605
H +E PC+ P C +W A++ C + CG+G + + C G
Sbjct: 273 GHCPHLVESVPCED---PMC-YRWLASE-GICFPDHGKCGLGHRILKAVCQNDRGED--- 324
Query: 606 VDDSNCPKEEKYNDSKPCEVP-EEKCP-SKWYAAPWSECTKSC------GKGLRFRSVVC 657
V S CP + K CE+P C S+W WS C++SC GK R R+++
Sbjct: 325 VSGSLCPVPPP-PERKSCEIPCRMDCVLSEW--TEWSSCSQSCSNKNSDGKQTRSRTILA 381
Query: 658 LRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
L G+ CP CN+ SC L
Sbjct: 382 L-AGEGGKPCPPSQALQEHRLCNDHSCMQL 410
Score = 66.9 bits (156), Expect = 7e-10
Identities = 98/374 (26%), Positives = 146/374 (39%), Gaps = 65/374 (17%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEG--LCDDGLKPATNQTCNTQACPP-QWVPG 392
+SSCS +C T RSR L + EG C ++ CN +C W
Sbjct: 357 WSSCSQSCSNKNSDGKQT-RSRTILALAGEGGKPCPPSQALQEHRLCNDHSCMQLHWETS 415
Query: 393 NWSRCSK-----------------RCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLG 435
W CS+ CG G ++R V C K + + K C D
Sbjct: 416 PWGPCSEDTLVTALNATIGWNGEATCGV-GIQTRRVFCVKSHVGQVMT----KRCPDSTR 470
Query: 436 PKPA--LYESCNVDAACPTWFISPWKPCDKLCGSG----QQTRQVVCYQK--NNGRI--- 484
P+ + C D C S W PC ++C +G +Q+R + Q+ N G+
Sbjct: 471 PETVRPCFLPCKKD--CIVTAFSEWTPCPRMCQAGNATVKQSRYRIIIQEAANGGQECPD 528
Query: 485 NVLSDDECSEEK--PLDR-QPCELEPCEGVDWMVSEW-TGC-DTCLATVRSRVAQCVTKD 539
+ + EC + P+ R +P + PC V V + TG + C +++R C++ D
Sbjct: 529 TLYEERECEDVSLCPVYRWKPQKWSPCILVPESVWQGITGSSEACGKGLQTRAVSCISDD 588
Query: 540 YRVVNSSFC--SYHPTPALEEPCDKDKLPACQVQWYATQWSK---CSVECGVGKKTRRVF 594
R C + P L + C +P C+ T WSK CS C K RR
Sbjct: 589 NRSAEMMECLKQTNGMPLLVQECT---VP-CREDCTFTAWSKFTPCSTNCEATKSRRRQL 644
Query: 595 CGKF-------DGASVMKVDDSNCPKEE----KYNDSKPCEVPEEKCPSKWYAAPWSECT 643
GK D V+ CP +E Y + C +PE + ++ +
Sbjct: 645 TGKSRKKEKCQDSDLYPLVETELCPCDEFISQPYGNWSDCILPEGRREPHRGLRVQAD-S 703
Query: 644 KSCGKGLRFRSVVC 657
K CG+GLRFR+V C
Sbjct: 704 KECGEGLRFRAVAC 717
Score = 39.9 bits (89), Expect = 0.096
Identities = 43/170 (25%), Positives = 62/170 (36%), Gaps = 19/170 (11%)
Query: 518 WTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
W G TC +++R CV V + C P PC C V ++ +W
Sbjct: 435 WNGEATCGVGIQTRRVFCVKSHVGQVMTKRCPDSTRPETVRPCFLPCKKDCIVTAFS-EW 493
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP----KEEKYNDSKPCEVPEEKCPSK 633
+ C C G T + + CP +E + D C V K P K
Sbjct: 494 TPCPRMCQAGNATVKQSRYRIIIQEAAN-GGQECPDTLYEERECEDVSLCPVYRWK-PQK 551
Query: 634 WYA------APWSECTKS---CGKGLRFRSVVCL---RGGKEFSDCPKKS 671
W + W T S CGKGL+ R+V C+ E +C K++
Sbjct: 552 WSPCILVPESVWQGITGSSEACGKGLQTRAVSCISDDNRSAEMMECLKQT 601
Score = 36.7 bits (81), Expect = 0.90
Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 586 VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKS 645
+G +TR+V C + DG + M S C ++ + C +P++ S+W + WS C+K+
Sbjct: 44 IGYQTRQVSCTRSDGQNAML---SLCLQDSFPLTVQSCIMPKDCETSQW--SSWSPCSKT 98
Query: 646 CGKG 649
C G
Sbjct: 99 CRSG 102
>BC019344-1|AAH19344.1| 740|Homo sapiens THSD7B protein protein.
Length = 740
Score = 83.4 bits (197), Expect = 8e-15
Identities = 100/374 (26%), Positives = 147/374 (39%), Gaps = 73/374 (19%)
Query: 343 CGGGIQSRDVTC----------RSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPG 392
CGGGIQ+R+V C R++E V++ LC G P +Q CN C +
Sbjct: 178 CGGGIQTREVYCAQSVPAAAALRAKEVSRPVEKALC-VGPAPLPSQLCNI-PCSTDCIVS 235
Query: 393 NWS--------RCSKRCGKDG--TRSREVRCEKIITNG-LPSVVDDKECFDLLGPKPALY 441
+WS C GK G TR R V E G P +V+ C D P Y
Sbjct: 236 SWSAWGLCIHENCHDPQGKKGFRTRQRHVLMESTGPAGHCPHLVESVPCED-----PMCY 290
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
+ C P CG G + + VC N R +S C P +R+
Sbjct: 291 RWLASEGIC--------FPDHGKCGLGHRILKAVC---QNDRGEDVSGSLCPVPPPPERK 339
Query: 502 PCELEPCEGVDWMVSEWTGCDTCLATVRSRVAQCVTKDYRVV----NSSFCSYHPTPALE 557
CE+ PC +D ++SEWT +C + ++ + R + P+ AL+
Sbjct: 340 SCEI-PCR-MDCVLSEWTEWSSCSQSCSNKNSDGKQTRSRTILALAGEGGKPCPPSQALQ 397
Query: 558 EPCDKDKLPACQVQWYATQWSKCSVE-----------------CGVGKKTRRVFCGKFDG 600
E + Q+ W + W CS + CGVG +TRRVFC K
Sbjct: 398 EHRLCNDHSCMQLHWETSPWGPCSEDTLVTALNATIGWNGEATCGVGIQTRRVFCVK--- 454
Query: 601 ASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGKG------LRFRS 654
+ V +V CP + +PC +P +K + W+ C + C G R+R
Sbjct: 455 SHVGQVMTKRCPDSTRPETVRPCFLPCKKDCIVTAFSEWTPCPRMCQAGNATVKQSRYRI 514
Query: 655 VV--CLRGGKEFSD 666
++ GG+E D
Sbjct: 515 IIQEAANGGQECPD 528
Score = 77.0 bits (181), Expect = 7e-13
Identities = 104/390 (26%), Positives = 155/390 (39%), Gaps = 72/390 (18%)
Query: 346 GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACPP-QWVPGNWSRCSKRCGK 403
G Q+R V+C +R + + LC P T Q+C + C QW +WS CSK C
Sbjct: 45 GYQTRQVSC-TRSDGQNAMLSLCLQDSFPLTVQSCIMPKDCETSQW--SSWSPCSKTCRS 101
Query: 404 D----GTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACP--TWFISP 457
G RSR + + G KEC +LL + + E + CP +W S
Sbjct: 102 GSLLPGFRSRSRNVKHMAIGG------GKECPELLEKEACIVEG-ELLQQCPRYSWRTSE 154
Query: 458 WKPCD----------------KLCGSGQQTRQVVCYQKNNGRINVLSDDE--------CS 493
WK C +CG G QTR+V C Q + + + C
Sbjct: 155 WKECQVSLLLEQQDPHWHVTGPVCGGGIQTREVYCAQSVPAAAALRAKEVSRPVEKALCV 214
Query: 494 EEKPLDRQPCELEPCEGVDWMVSEWTGCDTCL----ATVRSRVAQCVTKDYRVVNSSFCS 549
PL Q C + PC D +VS W+ C+ + + + + ++ S+ +
Sbjct: 215 GPAPLPSQLCNI-PC-STDCIVSSWSAWGLCIHENCHDPQGKKGFRTRQRHVLMESTGPA 272
Query: 550 YHPTPALEE-PCDKDKLPACQVQWYATQWSKCSVE---CGVGKKTRRVFCGKFDGASVMK 605
H +E PC+ P C +W A++ C + CG+G + + C G
Sbjct: 273 GHCPHLVESVPCED---PMC-YRWLASE-GICFPDHGKCGLGHRILKAVCQNDRGED--- 324
Query: 606 VDDSNCPKEEKYNDSKPCEVP-EEKCP-SKWYAAPWSECTKSC------GKGLRFRSVVC 657
V S CP + K CE+P C S+W WS C++SC GK R R+++
Sbjct: 325 VSGSLCPVPPP-PERKSCEIPCRMDCVLSEW--TEWSSCSQSCSNKNSDGKQTRSRTILA 381
Query: 658 LRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
L G+ CP CN+ SC L
Sbjct: 382 L-AGEGGKPCPPSQALQEHRLCNDHSCMQL 410
Score = 66.9 bits (156), Expect = 7e-10
Identities = 98/374 (26%), Positives = 146/374 (39%), Gaps = 65/374 (17%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEG--LCDDGLKPATNQTCNTQACPP-QWVPG 392
+SSCS +C T RSR L + EG C ++ CN +C W
Sbjct: 357 WSSCSQSCSNKNSDGKQT-RSRTILALAGEGGKPCPPSQALQEHRLCNDHSCMQLHWETS 415
Query: 393 NWSRCSK-----------------RCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLG 435
W CS+ CG G ++R V C K + + K C D
Sbjct: 416 PWGPCSEDTLVTALNATIGWNGEATCGV-GIQTRRVFCVKSHVGQVMT----KRCPDSTR 470
Query: 436 PKPA--LYESCNVDAACPTWFISPWKPCDKLCGSG----QQTRQVVCYQK--NNGRI--- 484
P+ + C D C S W PC ++C +G +Q+R + Q+ N G+
Sbjct: 471 PETVRPCFLPCKKD--CIVTAFSEWTPCPRMCQAGNATVKQSRYRIIIQEAANGGQECPD 528
Query: 485 NVLSDDECSEEK--PLDR-QPCELEPCEGVDWMVSEW-TGC-DTCLATVRSRVAQCVTKD 539
+ + EC + P+ R +P + PC V V + TG + C +++R C++ D
Sbjct: 529 TLYEERECEDVSLCPVYRWKPQKWSPCILVPESVWQGITGSSEACGKGLQTRAVSCISDD 588
Query: 540 YRVVNSSFC--SYHPTPALEEPCDKDKLPACQVQWYATQWSK---CSVECGVGKKTRRVF 594
R C + P L + C +P C+ T WSK CS C K RR
Sbjct: 589 NRSAEMMECLKQTNGMPLLVQECT---VP-CREDCTFTAWSKFTPCSTNCEATKSRRRQL 644
Query: 595 CGKF-------DGASVMKVDDSNCPKEE----KYNDSKPCEVPEEKCPSKWYAAPWSECT 643
GK D V+ CP +E Y + C +PE + ++ +
Sbjct: 645 TGKSRKKEKCQDSDLYPLVETELCPCDEFISQPYGNWSDCILPEGRREPHRGLRVQAD-S 703
Query: 644 KSCGKGLRFRSVVC 657
K CG+GLRFR+V C
Sbjct: 704 KECGEGLRFRAVAC 717
Score = 39.9 bits (89), Expect = 0.096
Identities = 43/170 (25%), Positives = 62/170 (36%), Gaps = 19/170 (11%)
Query: 518 WTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQW 577
W G TC +++R CV V + C P PC C V ++ +W
Sbjct: 435 WNGEATCGVGIQTRRVFCVKSHVGQVMTKRCPDSTRPETVRPCFLPCKKDCIVTAFS-EW 493
Query: 578 SKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP----KEEKYNDSKPCEVPEEKCPSK 633
+ C C G T + + CP +E + D C V K P K
Sbjct: 494 TPCPRMCQAGNATVKQSRYRIIIQEAAN-GGQECPDTLYEERECEDVSLCPVYRWK-PQK 551
Query: 634 WYA------APWSECTKS---CGKGLRFRSVVCL---RGGKEFSDCPKKS 671
W + W T S CGKGL+ R+V C+ E +C K++
Sbjct: 552 WSPCILVPESVWQGITGSSEACGKGLQTRAVSCISDDNRSAEMMECLKQT 601
Score = 36.7 bits (81), Expect = 0.90
Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 5/64 (7%)
Query: 586 VGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKS 645
+G +TR+V C + DG + M S C ++ + C +P++ S+W + WS C+K+
Sbjct: 44 IGYQTRQVSCTRSDGQNAML---SLCLQDSFPLTVQSCIMPKDCETSQW--SSWSPCSKT 98
Query: 646 CGKG 649
C G
Sbjct: 99 CRSG 102
>X52022-1|CAA36267.1| 3176|Homo sapiens collagen type VI, alpha 3
chain protein.
Length = 3176
Score = 81.4 bits (192), Expect = 3e-14
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEI 1817
D+C LP + G C ++ KW+YD + K C +F+YGGCGGNENKF SQ ECE C+ +
Sbjct: 3109 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPV 3164
Score = 75.8 bits (178), Expect = 2e-12
Identities = 27/53 (50%), Positives = 38/53 (71%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
D+C+LP G C D I+ W+YD + +C++F YGGCGGN+N+F S+ ECE C
Sbjct: 3109 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 3161
Score = 71.3 bits (167), Expect = 3e-11
Identities = 26/51 (50%), Positives = 35/51 (68%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C L KD G+ RD+ + WYYD C+RFWYGG GN N+F +++EC+ VC
Sbjct: 3111 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 3161
Score = 70.1 bits (164), Expect = 8e-11
Identities = 26/59 (44%), Positives = 37/59 (62%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
D CKLPK +G C + ++WYYD + C++F YGGC GN N F +++ C+ C P K
Sbjct: 3109 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 3167
Score = 65.3 bits (152), Expect = 2e-09
Identities = 25/64 (39%), Positives = 37/64 (57%)
Query: 2039 AFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
A + ++C P D G CR ++ K+Y+D +SC F YGGC G N+F + EC +VC
Sbjct: 3104 ALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 3163
Query: 2099 YIGK 2102
+ K
Sbjct: 3164 VLAK 3167
Score = 60.9 bits (141), Expect = 5e-08
Identities = 23/54 (42%), Positives = 29/54 (53%)
Query: 1838 SEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
++ C D G C F +W YD CA F YGGCGGN N F S++ C+ C
Sbjct: 3108 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 3161
Score = 59.7 bits (138), Expect = 1e-07
Identities = 22/55 (40%), Positives = 33/55 (60%)
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP 1697
D C LP + G+C +W ++ T+ C F +GGC GN N+FGS+ C++ C P
Sbjct: 3109 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 3163
Score = 56.0 bits (129), Expect = 1e-06
Identities = 18/51 (35%), Positives = 28/51 (54%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
C P+++G C + W++ P C F+Y GCGGN+N+F + C C
Sbjct: 3111 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 3161
>BX641155-1|CAE46068.1| 558|Homo sapiens hypothetical protein
protein.
Length = 558
Score = 81.4 bits (192), Expect = 3e-14
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEI 1817
D+C LP + G C ++ KW+YD + K C +F+YGGCGGNENKF SQ ECE C+ +
Sbjct: 491 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPV 546
Score = 75.8 bits (178), Expect = 2e-12
Identities = 27/53 (50%), Positives = 38/53 (71%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
D+C+LP G C D I+ W+YD + +C++F YGGCGGN+N+F S+ ECE C
Sbjct: 491 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 543
Score = 71.3 bits (167), Expect = 3e-11
Identities = 26/51 (50%), Positives = 35/51 (68%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C L KD G+ RD+ + WYYD C+RFWYGG GN N+F +++EC+ VC
Sbjct: 493 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 543
Score = 70.1 bits (164), Expect = 8e-11
Identities = 26/59 (44%), Positives = 37/59 (62%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
D CKLPK +G C + ++WYYD + C++F YGGC GN N F +++ C+ C P K
Sbjct: 491 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 549
Score = 65.3 bits (152), Expect = 2e-09
Identities = 25/64 (39%), Positives = 37/64 (57%)
Query: 2039 AFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
A + ++C P D G CR ++ K+Y+D +SC F YGGC G N+F + EC +VC
Sbjct: 486 ALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 545
Query: 2099 YIGK 2102
+ K
Sbjct: 546 VLAK 549
Score = 60.9 bits (141), Expect = 5e-08
Identities = 23/54 (42%), Positives = 29/54 (53%)
Query: 1838 SEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
++ C D G C F +W YD CA F YGGCGGN N F S++ C+ C
Sbjct: 490 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 543
Score = 59.7 bits (138), Expect = 1e-07
Identities = 22/55 (40%), Positives = 33/55 (60%)
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP 1697
D C LP + G+C +W ++ T+ C F +GGC GN N+FGS+ C++ C P
Sbjct: 491 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 545
Score = 56.0 bits (129), Expect = 1e-06
Identities = 18/51 (35%), Positives = 28/51 (54%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
C P+++G C + W++ P C F+Y GCGGN+N+F + C C
Sbjct: 493 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 543
>BC033174-1|AAH33174.1| 979|Homo sapiens Similar to collagen, type
VI, alpha 3 protein.
Length = 979
Score = 81.4 bits (192), Expect = 3e-14
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEI 1817
D+C LP + G C ++ KW+YD + K C +F+YGGCGGNENKF SQ ECE C+ +
Sbjct: 912 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPV 967
Score = 75.8 bits (178), Expect = 2e-12
Identities = 27/53 (50%), Positives = 38/53 (71%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
D+C+LP G C D I+ W+YD + +C++F YGGCGGN+N+F S+ ECE C
Sbjct: 912 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 964
Score = 71.3 bits (167), Expect = 3e-11
Identities = 26/51 (50%), Positives = 35/51 (68%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C L KD G+ RD+ + WYYD C+RFWYGG GN N+F +++EC+ VC
Sbjct: 914 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 964
Score = 70.1 bits (164), Expect = 8e-11
Identities = 26/59 (44%), Positives = 37/59 (62%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
D CKLPK +G C + ++WYYD + C++F YGGC GN N F +++ C+ C P K
Sbjct: 912 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 970
Score = 65.3 bits (152), Expect = 2e-09
Identities = 25/64 (39%), Positives = 37/64 (57%)
Query: 2039 AFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
A + ++C P D G CR ++ K+Y+D +SC F YGGC G N+F + EC +VC
Sbjct: 907 ALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 966
Query: 2099 YIGK 2102
+ K
Sbjct: 967 VLAK 970
Score = 60.9 bits (141), Expect = 5e-08
Identities = 23/54 (42%), Positives = 29/54 (53%)
Query: 1838 SEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
++ C D G C F +W YD CA F YGGCGGN N F S++ C+ C
Sbjct: 911 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 964
Score = 59.7 bits (138), Expect = 1e-07
Identities = 22/55 (40%), Positives = 33/55 (60%)
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP 1697
D C LP + G+C +W ++ T+ C F +GGC GN N+FGS+ C++ C P
Sbjct: 912 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 966
Score = 56.0 bits (129), Expect = 1e-06
Identities = 18/51 (35%), Positives = 28/51 (54%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
C P+++G C + W++ P C F+Y GCGGN+N+F + C C
Sbjct: 914 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 964
>AC112715-1|AAY14906.1| 588|Homo sapiens unknown protein.
Length = 588
Score = 81.4 bits (192), Expect = 3e-14
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEI 1817
D+C LP + G C ++ KW+YD + K C +F+YGGCGGNENKF SQ ECE C+ +
Sbjct: 521 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPV 576
Score = 75.8 bits (178), Expect = 2e-12
Identities = 27/53 (50%), Positives = 38/53 (71%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
D+C+LP G C D I+ W+YD + +C++F YGGCGGN+N+F S+ ECE C
Sbjct: 521 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 573
Score = 71.3 bits (167), Expect = 3e-11
Identities = 26/51 (50%), Positives = 35/51 (68%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C L KD G+ RD+ + WYYD C+RFWYGG GN N+F +++EC+ VC
Sbjct: 523 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 573
Score = 70.1 bits (164), Expect = 8e-11
Identities = 26/59 (44%), Positives = 37/59 (62%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
D CKLPK +G C + ++WYYD + C++F YGGC GN N F +++ C+ C P K
Sbjct: 521 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 579
Score = 65.3 bits (152), Expect = 2e-09
Identities = 25/64 (39%), Positives = 37/64 (57%)
Query: 2039 AFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
A + ++C P D G CR ++ K+Y+D +SC F YGGC G N+F + EC +VC
Sbjct: 516 ALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 575
Query: 2099 YIGK 2102
+ K
Sbjct: 576 VLAK 579
Score = 60.9 bits (141), Expect = 5e-08
Identities = 23/54 (42%), Positives = 29/54 (53%)
Query: 1838 SEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
++ C D G C F +W YD CA F YGGCGGN N F S++ C+ C
Sbjct: 520 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 573
Score = 59.7 bits (138), Expect = 1e-07
Identities = 22/55 (40%), Positives = 33/55 (60%)
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP 1697
D C LP + G+C +W ++ T+ C F +GGC GN N+FGS+ C++ C P
Sbjct: 521 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 575
Score = 56.0 bits (129), Expect = 1e-06
Identities = 18/51 (35%), Positives = 28/51 (54%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
C P+++G C + W++ P C F+Y GCGGN+N+F + C C
Sbjct: 523 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 573
>AB209636-1|BAD92873.1| 1702|Homo sapiens alpha 3 type VI collagen
isoform 5 precursor variant protein.
Length = 1702
Score = 81.4 bits (192), Expect = 3e-14
Identities = 30/56 (53%), Positives = 40/56 (71%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEI 1817
D+C LP + G C ++ KW+YD + K C +F+YGGCGGNENKF SQ ECE C+ +
Sbjct: 1635 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPV 1690
Score = 75.8 bits (178), Expect = 2e-12
Identities = 27/53 (50%), Positives = 38/53 (71%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
D+C+LP G C D I+ W+YD + +C++F YGGCGGN+N+F S+ ECE C
Sbjct: 1635 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 1687
Score = 71.3 bits (167), Expect = 3e-11
Identities = 26/51 (50%), Positives = 35/51 (68%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C L KD G+ RD+ + WYYD C+RFWYGG GN N+F +++EC+ VC
Sbjct: 1637 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 1687
Score = 70.1 bits (164), Expect = 8e-11
Identities = 26/59 (44%), Positives = 37/59 (62%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
D CKLPK +G C + ++WYYD + C++F YGGC GN N F +++ C+ C P K
Sbjct: 1635 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 1693
Score = 65.3 bits (152), Expect = 2e-09
Identities = 25/64 (39%), Positives = 37/64 (57%)
Query: 2039 AFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKN 2098
A + ++C P D G CR ++ K+Y+D +SC F YGGC G N+F + EC +VC
Sbjct: 1630 ALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 1689
Query: 2099 YIGK 2102
+ K
Sbjct: 1690 VLAK 1693
Score = 60.9 bits (141), Expect = 5e-08
Identities = 23/54 (42%), Positives = 29/54 (53%)
Query: 1838 SEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
++ C D G C F +W YD CA F YGGCGGN N F S++ C+ C
Sbjct: 1634 TDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 1687
Score = 59.7 bits (138), Expect = 1e-07
Identities = 22/55 (40%), Positives = 33/55 (60%)
Query: 1643 DQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRCDP 1697
D C LP + G+C +W ++ T+ C F +GGC GN N+FGS+ C++ C P
Sbjct: 1635 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAP 1689
Score = 56.0 bits (129), Expect = 1e-06
Identities = 18/51 (35%), Positives = 28/51 (54%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
C P+++G C + W++ P C F+Y GCGGN+N+F + C C
Sbjct: 1637 CKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVC 1687
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4586 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4639
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4640 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4695
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4696 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4749
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4750 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4808
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4809 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4858
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4579 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4633
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4634 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4685
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4686 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4739
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4740 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4796
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4797 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4841
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4536 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4589
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4590 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4697
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4757
Query: 688 GEGS 691
G S
Sbjct: 4758 GNWS 4761
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4826 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4885
Query: 117 VTF 119
V F
Sbjct: 4886 VEF 4888
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4541 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4769 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4655 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4586 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4639
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4640 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4695
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4696 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4749
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4750 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4808
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4809 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4858
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4579 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4633
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4634 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4685
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4686 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4739
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4740 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4796
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4797 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4841
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4536 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4589
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4590 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4697
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4757
Query: 688 GEGS 691
G S
Sbjct: 4758 GNWS 4761
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4826 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4885
Query: 117 VTF 119
V F
Sbjct: 4886 VEF 4888
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4541 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4769 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4655 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4586 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4639
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4640 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4695
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4696 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4749
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4750 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4808
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4809 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4858
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4579 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4633
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4634 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4685
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4686 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4739
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4740 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4796
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4797 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4841
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4536 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4589
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4590 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4697
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4757
Query: 688 GEGS 691
G S
Sbjct: 4758 GNWS 4761
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4826 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4885
Query: 117 VTF 119
V F
Sbjct: 4886 VEF 4888
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4541 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4769 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4655 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4586 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4639
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4640 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4695
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4696 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4749
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4750 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4808
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4809 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4858
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4579 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4633
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4634 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4685
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4686 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4739
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4740 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4796
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4797 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4841
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4536 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4589
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4590 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4697
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4757
Query: 688 GEGS 691
G S
Sbjct: 4758 GNWS 4761
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4826 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4885
Query: 117 VTF 119
V F
Sbjct: 4886 VEF 4888
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4541 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4769 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4655 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4586 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4639
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4640 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4695
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4696 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4749
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4750 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4808
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4809 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4858
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4579 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4633
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4634 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4685
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4686 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4739
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4740 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4796
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4797 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4841
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4536 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4589
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4590 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4697
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4757
Query: 688 GEGS 691
G S
Sbjct: 4758 GNWS 4761
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4826 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4885
Query: 117 VTF 119
V F
Sbjct: 4886 VEF 4888
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4541 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4769 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4655 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4586 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4639
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4640 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4695
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4696 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4749
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4750 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4808
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4809 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4858
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4579 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4633
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4634 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4685
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4686 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4739
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4740 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4796
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4797 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4841
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4536 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4589
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4590 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4697
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4757
Query: 688 GEGS 691
G S
Sbjct: 4758 GNWS 4761
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4826 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4885
Query: 117 VTF 119
V F
Sbjct: 4886 VEF 4888
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4541 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4769 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4655 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4586 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4639
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4640 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4695
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4696 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4749
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4750 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4808
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4809 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4858
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4579 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4633
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4634 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4685
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4686 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4739
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4740 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4796
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4797 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4841
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4536 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4589
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4590 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4697
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4757
Query: 688 GEGS 691
G S
Sbjct: 4758 GNWS 4761
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4826 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4885
Query: 117 VTF 119
V F
Sbjct: 4886 VEF 4888
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4541 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4769 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4655 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4585
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4586 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4639
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4640 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4695
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4696 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4749
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4750 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4808
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4809 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4858
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4859 QVTRCNVQAC 4868
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4579 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4633
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4634 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4685
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4686 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4739
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4740 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4796
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4797 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4841
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4536 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4589
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4590 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4645
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4697
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4698 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4757
Query: 688 GEGS 691
G S
Sbjct: 4758 GNWS 4761
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4826 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4885
Query: 117 VTF 119
V F
Sbjct: 4886 VEF 4888
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4541 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4584
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4769 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4812
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4655 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4698
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4712 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4755
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 77.4 bits (182), Expect = 5e-13
Identities = 89/370 (24%), Positives = 137/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 1566 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 1623
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 1624 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 1677
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 1678 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 1733
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C P G + W+ C +C R R C + C + + C
Sbjct: 1734 NC---PVHGKWATWASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 1787
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 1788 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 1846
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 1847 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 1896
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 1897 QVTRCNVQAC 1906
Score = 70.5 bits (165), Expect = 6e-11
Identities = 74/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 1617 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 1671
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 1672 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 1723
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C V TW + W C CG G + R C + + +C
Sbjct: 1724 ETQMQVCNERNCPVHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 1777
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 1778 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 1834
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 1835 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 1879
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 1574 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 1627
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 1628 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 1683
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 1684 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 1735
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 1736 PVHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 1795
Query: 688 GEGS 691
G S
Sbjct: 1796 GNWS 1799
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 1864 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 1923
Query: 117 VTF 119
V F
Sbjct: 1924 VEF 1926
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 1579 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 1622
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 1807 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 1850
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 1693 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 1736
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 1750 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 1793
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 77.4 bits (182), Expect = 5e-13
Identities = 88/370 (23%), Positives = 138/370 (37%), Gaps = 46/370 (12%)
Query: 332 VHGNFS------SCSATCGGGIQSRDVTCRSREELEVVDEGLC---DDGLKPATNQTCNT 382
VHG FS +CS TCG GIQ R C + L C D ++ N+ C
Sbjct: 4529 VHGGFSQWSAWRACSVTCGKGIQKRSRLCN--QPLPANGGKPCQGSDLEMRNCQNKPCPV 4586
Query: 383 QACPPQWVPGNWSRCSKRCGKDG-TRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALY 441
+W W C++ CG+ TR+R + G P + E + +P
Sbjct: 4587 DGSWSEW--SLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEII-MCNIRP--- 4640
Query: 442 ESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQ 501
C V A W PW C + CG G QTR +C D ++ + + +
Sbjct: 4641 --CPVHGAWSAW--QPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNER 4696
Query: 502 PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC 560
C + + W + W+ C +C R R C + C + + C
Sbjct: 4697 NCPIHG-KWATW--ASWSACSVSCGGGARQRTRGC-SDPVPQYGGRKCE--GSDVQSDFC 4750
Query: 561 DKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYND 619
+ D P W + W CS C G+ R C ++ + + ++ N
Sbjct: 4751 NSDPCPT-HGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNT 4809
Query: 620 SKPCEVPEEKCPSKWYAAPWSECTKSCGKGLRFRSVVC-----LRGGKEFSDCPKKSLPD 674
C P + W++ WS+C+ SCG G + R +C ++GG+ CP +
Sbjct: 4810 DM-C--PVDGSWGSWHS--WSQCSASCGGGEKTRKRLCDHPVPVKGGR---PCPGDT--T 4859
Query: 675 SAGSCNEQSC 684
CN Q+C
Sbjct: 4860 QVTRCNVQAC 4869
Score = 70.1 bits (164), Expect = 8e-11
Identities = 73/285 (25%), Positives = 108/285 (37%), Gaps = 31/285 (10%)
Query: 320 EKAPLPTQRYSWVHGN-FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
+ P P SW + + C+ +CG G Q+R TC + V G +G
Sbjct: 4580 QNKPCPVDG-SWSEWSLWEECTRSCGRGNQTRTRTCNNPS---VQHGGRPCEG-NAVEII 4634
Query: 379 TCNTQACPPQ-----WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDL 433
CN + CP W P W CS+ CGK GT++R C N P C
Sbjct: 4635 MCNIRPCPVHGAWSAWQP--WGTCSESCGK-GTQTRARLC-----NNPPPAFGGSYCDGA 4686
Query: 434 LGPKPALYE-SCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDEC 492
E +C + TW + W C CG G + R C + + +C
Sbjct: 4687 ETQMQVCNERNCPIHGKWATW--ASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKC 4740
Query: 493 SEEKPLDRQPCELEPCEGV-DWMVSEWTGCDTCLATVRS-RVAQCVTKDYRVVNSSFCSY 550
E + C +PC +W S W+G TC T ++ + T D ++ +
Sbjct: 4741 -EGSDVQSDFCNSDPCPTHGNW--SPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRAC 4797
Query: 551 HPTPALEEPCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFC 595
+ + C+ D P WS+CS CG G+KTR+ C
Sbjct: 4798 GGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC 4842
Score = 63.7 bits (148), Expect = 7e-09
Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 26/244 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W+ C CG G Q R +C N + C + L+ + C+ +PC VD
Sbjct: 4537 SAWRACSVTCGKGIQKRSRLC----NQPLPANGGKPC-QGSDLEMRNCQNKPCP-VDGSW 4590
Query: 516 SEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCD--KDKLPACQVQ-- 571
SEW+ + C + R Q T R N+ + P + + C V
Sbjct: 4591 SEWSLWEECTRSC-GRGNQTRT---RTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA 4646
Query: 572 WYATQ-WSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W A Q W CS CG G +TR C A S C E + C E C
Sbjct: 4647 WSAWQPWGTCSESCGKGTQTRARLCNNPPPA----FGGSYCDGAE--TQMQVCN--ERNC 4698
Query: 631 P--SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEAL 687
P KW A WS C+ SCG G R R+ C ++ + + CN C
Sbjct: 4699 PIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH 4758
Query: 688 GEGS 691
G S
Sbjct: 4759 GNWS 4762
Score = 43.2 bits (97), Expect = 0.010
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCPENSLDFRAEQCAQYNN 116
CS +CGGG ++KR+C P G C G T+ C Q CP R N+
Sbjct: 4827 CSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACPGGPQRARGSVIGNIND 4886
Query: 117 VTF 119
V F
Sbjct: 4887 VEF 4889
Score = 41.5 bits (93), Expect = 0.032
Identities = 17/44 (38%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CS TCG G+ + R+C + P NG C G D + +C+ + CP
Sbjct: 4542 CSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCP 4585
Score = 39.1 bits (87), Expect = 0.17
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGP-NGEPQCTGGDTKYFSCETQDCP 100
CSRTC GG + R C P NG C G D++ C T CP
Sbjct: 4770 CSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCP 4813
Score = 35.9 bits (79), Expect = 1.6
Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CG G ++ R+C P G C G +T+ C ++CP
Sbjct: 4656 CSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCP 4699
Score = 35.9 bits (79), Expect = 1.6
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCP 100
CS +CGGG + R C + P G +C G D + C + CP
Sbjct: 4713 CSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCP 4756
>BX640951-1|CAE45975.1| 370|Homo sapiens hypothetical protein
protein.
Length = 370
Score = 75.8 bits (178), Expect = 2e-12
Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 6/134 (4%)
Query: 314 EYSLPIEKAPLPTQRYSWVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGL 372
E + ++KA L Q Y W ++CSA+CG G+Q + C V+ C +
Sbjct: 235 EAGVLMQKASLVIQDYWWSVDRLATCSASCGNRGVQQPRLRCLLNST--EVNPAHCAGKV 292
Query: 373 KPATNQ-TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECF 431
+PA CN + CP +W+ +WS C++ CG G ++R V C+K+ +G+ + V + C
Sbjct: 293 RPAVQPIACNRRDCPSRWMVTSWSACTRSCG-GGVQTRRVTCQKLKASGISTPVSNDMCT 351
Query: 432 DLLGPKPALYESCN 445
+ +P ++CN
Sbjct: 352 Q-VAKRPVDTQACN 364
Score = 62.1 bits (144), Expect = 2e-08
Identities = 38/125 (30%), Positives = 63/125 (50%), Gaps = 13/125 (10%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYE-SCNVD 447
W + CS CG G + +RC + N + V+ C + +PA+ +CN
Sbjct: 252 WSVDRLATCSASCGNRGVQQPRLRC---LLNS--TEVNPAHCAGKV--RPAVQPIACN-R 303
Query: 448 AACPT-WFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSE--EKPLDRQPC 503
CP+ W ++ W C + CG G QTR+V C + K +G +S+D C++ ++P+D Q C
Sbjct: 304 RDCPSRWMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQAC 363
Query: 504 ELEPC 508
+ C
Sbjct: 364 NQQLC 368
Score = 48.8 bits (111), Expect = 2e-04
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 6/87 (6%)
Query: 572 WYATQWSKCSVECGV-GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKC 630
W + + CS CG G + R+ C + +V+ ++C + + +P C
Sbjct: 252 WSVDRLATCSASCGNRGVQQPRLRCL----LNSTEVNPAHCAGKVR-PAVQPIACNRRDC 306
Query: 631 PSKWYAAPWSECTKSCGKGLRFRSVVC 657
PS+W WS CT+SCG G++ R V C
Sbjct: 307 PSRWMVTSWSACTRSCGGGVQTRRVTC 333
Score = 46.4 bits (105), Expect = 0.001
Identities = 21/59 (35%), Positives = 33/59 (55%), Gaps = 4/59 (6%)
Query: 331 WVHGNFSSCSATCGGGIQSRDVTCRSREELEV---VDEGLCDDGLK-PATNQTCNTQAC 385
W+ ++S+C+ +CGGG+Q+R VTC+ + + V +C K P Q CN Q C
Sbjct: 310 WMVTSWSACTRSCGGGVQTRRVTCQKLKASGISTPVSNDMCTQVAKRPVDTQACNQQLC 368
Score = 45.2 bits (102), Expect = 0.003
Identities = 26/84 (30%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 543 VNSSFCSYHPTPALEE-PCDKDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGA 601
VN + C+ PA++ C++ P+ +W T WS C+ CG G +TRRV C K +
Sbjct: 283 VNPAHCAGKVRPAVQPIACNRRDCPS---RWMVTSWSACTRSCGGGVQTRRVTCQKLKAS 339
Query: 602 SV-MKVDDSNCPKEEKYN-DSKPC 623
+ V + C + K D++ C
Sbjct: 340 GISTPVSNDMCTQVAKRPVDTQAC 363
>AB051390-1|BAB18461.1| 807|Homo sapiens VSGP/F-spondin protein.
Length = 807
Score = 73.7 bits (173), Expect = 6e-12
Identities = 74/273 (27%), Positives = 109/273 (39%), Gaps = 45/273 (16%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVD- 447
W P WS CS G R R+ + + +P C D +P + C+ +
Sbjct: 448 WSP--WSACSSSTCDKGKRMRQRMLKAQLDLSVP-------CPDTQDFQPCMGPGCSDED 498
Query: 448 -AACPTWFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSEEKPLDRQPCEL 505
+ C W PC CG G ++R+ Q +G + L +E EK + C
Sbjct: 499 GSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEEM--EKCTVNEECSP 556
Query: 506 EPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC---D 561
C +W EW C TC ++ R + S C + A E C +
Sbjct: 557 SSCLMTEW--GEWDECSATCGMGMKKRHRMIKMNP---ADGSMCKAETSQA--EKCMMPE 609
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
+P W ++WS CSV CG G +TR+ S+ ++ D N E +
Sbjct: 610 CHTIPCLLSPW--SEWSDCSVTCGKGMRTRQRML-----KSLAELGDCN----EDLEQVE 658
Query: 622 PCEVPEEKCP-----SKWYAAPWSECTKSCGKG 649
C +PE CP ++W + WSEC KSCGKG
Sbjct: 659 KCMLPE--CPIDCELTEW--SQWSECNKSCGKG 687
Score = 70.5 bits (165), Expect = 6e-11
Identities = 98/384 (25%), Positives = 155/384 (40%), Gaps = 62/384 (16%)
Query: 336 FSSCSA-TCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQ---ACP-PQWV 390
+S+CS+ TC G + R +++ +L V D +P C+ + C +W+
Sbjct: 451 WSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQD--FQPCMGPGCSDEDGSTCTMSEWI 508
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
WS CS CG G RSRE ++ +G + +E K + E C+ +
Sbjct: 509 --TWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPTEEM-----EKCTVNEECSPSSCL 560
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
T + W C CG G + R + K N + E S+ + C PC
Sbjct: 561 MTEW-GEWDECSATCGMGMKKRHRMI--KMNPADGSMCKAETSQAEKCMMPECHTIPCLL 617
Query: 511 VDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQ 569
W SEW+ C TC +R+R Q + K + C+ LE+ +K LP C
Sbjct: 618 SPW--SEWSDCSVTCGKGMRTR--QRMLKSLAELGD--CNED----LEQ-VEKCMLPECP 666
Query: 570 VQWYAT---QWSKCSVECGVGK--KTRRV-FCGKFDGASVMK-VDDSNC----------- 611
+ T QWS+C+ CG G +TR + +F GA + V C
Sbjct: 667 IDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSI 726
Query: 612 --PKEEKYNDSKPCEVPEEKCPSKWYA-------APWSECTKSCGKGLRFRSVVCLRGGK 662
P+ + +S+ E +E+ + + WSECTK CG G++ R + + K
Sbjct: 727 QKPRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFK 786
Query: 663 --EFSDCPKKSLPDSAGSCNEQSC 684
+F+ C K +CN C
Sbjct: 787 SSQFTSCKDKK---EIRACNVHPC 807
Score = 56.4 bits (130), Expect = 1e-06
Identities = 62/223 (27%), Positives = 99/223 (44%), Gaps = 32/223 (14%)
Query: 456 SPWKPCDK-LCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC---EGV 511
SPW C C G++ RQ + K ++V C + + D QPC C +G
Sbjct: 449 SPWSACSSSTCDKGKRMRQRML--KAQLDLSV----PCPDTQ--DFQPCMGPGCSDEDGS 500
Query: 512 DWMVSEWTGCDTCLAT--VRSRVAQCVTKDYRVVNSSFCSYHPTPALEE-PCDKDKLPAC 568
+SEW C + + R + K + + S C+ PT +E+ +++ P+
Sbjct: 501 TCTMSEWITWSPCSISCGMGMRSRERYVKQFPE-DGSVCTL-PTEEMEKCTVNEECSPSS 558
Query: 569 QVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPE- 627
+ +W +CS CG+G K R K + A D S C E + ++ C +PE
Sbjct: 559 CLMTEWGEWDECSATCGMGMKKRHRMI-KMNPA-----DGSMCKAET--SQAEKCMMPEC 610
Query: 628 EKCP---SKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDC 667
P S W + WS+C+ +CGKG+R R + L+ E DC
Sbjct: 611 HTIPCLLSPW--SEWSDCSVTCGKGMRTRQRM-LKSLAELGDC 650
Score = 50.8 bits (116), Expect = 5e-05
Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 20/143 (13%)
Query: 334 GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN---QTCNTQAC-PPQW 389
G + CSATCG G++ R ++ D +C A C+T C W
Sbjct: 565 GEWDECSATCGMGMKKR----HRMIKMNPADGSMCKAETSQAEKCMMPECHTIPCLLSPW 620
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
WS CS CGK G R+R+ + + G D E DL + + C +D
Sbjct: 621 --SEWSDCSVTCGK-GMRTRQRMLKSLAELG-----DCNE--DLEQVEKCMLPECPIDCE 670
Query: 450 CPTWFISPWKPCDKLCGSGQQTR 472
W S W C+K CG G R
Sbjct: 671 LTEW--SQWSECNKSCGKGHVIR 691
>AB018305-1|BAA34482.2| 724|Homo sapiens KIAA0762 protein protein.
Length = 724
Score = 73.7 bits (173), Expect = 6e-12
Identities = 74/273 (27%), Positives = 109/273 (39%), Gaps = 45/273 (16%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVD- 447
W P WS CS G R R+ + + +P C D +P + C+ +
Sbjct: 365 WSP--WSACSSSTCDKGKRMRQRMLKAQLDLSVP-------CPDTQDFQPCMGPGCSDED 415
Query: 448 -AACPTWFISPWKPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSEEKPLDRQPCEL 505
+ C W PC CG G ++R+ Q +G + L +E EK + C
Sbjct: 416 GSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEET--EKCTVNEECSP 473
Query: 506 EPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPC---D 561
C +W EW C TC ++ R + S C + A E C +
Sbjct: 474 SSCLMTEW--GEWDECSATCGMGMKKRHRMIKMNP---ADGSMCKAETSQA--EKCMMPE 526
Query: 562 KDKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSK 621
+P W ++WS CSV CG G +TR+ S+ ++ D N E +
Sbjct: 527 CHTIPCLLSPW--SEWSDCSVTCGKGMRTRQRML-----KSLAELGDCN----EDLEQVE 575
Query: 622 PCEVPEEKCP-----SKWYAAPWSECTKSCGKG 649
C +PE CP ++W + WSEC KSCGKG
Sbjct: 576 KCMLPE--CPIDCELTEW--SQWSECNKSCGKG 604
Score = 68.9 bits (161), Expect = 2e-10
Identities = 99/384 (25%), Positives = 155/384 (40%), Gaps = 62/384 (16%)
Query: 336 FSSCSA-TCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQ---ACP-PQWV 390
+S+CS+ TC G + R +++ +L V D +P C+ + C +W+
Sbjct: 368 WSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQD--FQPCMGPGCSDEDGSTCTMSEWI 425
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
WS CS CG G RSRE ++ +G + +E K + E C+ +
Sbjct: 426 --TWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPTEET-----EKCTVNEECSPSSCL 477
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
T + W C CG G + R + K N + E S+ + C PC
Sbjct: 478 MTEW-GEWDECSATCGMGMKKRHRMI--KMNPADGSMCKAETSQAEKCMMPECHTIPCLL 534
Query: 511 VDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQ 569
W SEW+ C TC +R+R Q + K + C+ LE+ +K LP C
Sbjct: 535 SPW--SEWSDCSVTCGKGMRTR--QRMLKSLAELGD--CNED----LEQ-VEKCMLPECP 583
Query: 570 VQWYAT---QWSKCSVECGVGK--KTRRV-FCGKFDGASVMK-VDDSNC--------PKE 614
+ T QWS+C+ CG G +TR + +F GA + V C P
Sbjct: 584 IDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSI 643
Query: 615 EKY-----NDSKPCEVPEEKCPSKWYA-------APWSECTKSCGKGLRFRSVVCLRGGK 662
+K +S+ E +E+ + + WSECTK CG G++ R + + K
Sbjct: 644 QKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFK 703
Query: 663 --EFSDCPKKSLPDSAGSCNEQSC 684
+F+ C K +CN C
Sbjct: 704 SSQFTSCKDKK---EIRACNVHPC 724
Score = 55.2 bits (127), Expect = 2e-06
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 32/223 (14%)
Query: 456 SPWKPCDK-LCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC---EGV 511
SPW C C G++ RQ + K ++V C + + D QPC C +G
Sbjct: 366 SPWSACSSSTCDKGKRMRQRML--KAQLDLSV----PCPDTQ--DFQPCMGPGCSDEDGS 417
Query: 512 DWMVSEWTGCDTCLAT--VRSRVAQCVTKDYRVVNSSFCSYHPTPALEE-PCDKDKLPAC 568
+SEW C + + R + K + + S C+ PT E+ +++ P+
Sbjct: 418 TCTMSEWITWSPCSISCGMGMRSRERYVKQFPE-DGSVCTL-PTEETEKCTVNEECSPSS 475
Query: 569 QVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPE- 627
+ +W +CS CG+G K R K + A D S C E + ++ C +PE
Sbjct: 476 CLMTEWGEWDECSATCGMGMKKRHRMI-KMNPA-----DGSMCKAET--SQAEKCMMPEC 527
Query: 628 EKCP---SKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDC 667
P S W + WS+C+ +CGKG+R R + L+ E DC
Sbjct: 528 HTIPCLLSPW--SEWSDCSVTCGKGMRTRQRM-LKSLAELGDC 567
Score = 50.8 bits (116), Expect = 5e-05
Identities = 42/143 (29%), Positives = 57/143 (39%), Gaps = 20/143 (13%)
Query: 334 GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATN---QTCNTQAC-PPQW 389
G + CSATCG G++ R ++ D +C A C+T C W
Sbjct: 482 GEWDECSATCGMGMKKR----HRMIKMNPADGSMCKAETSQAEKCMMPECHTIPCLLSPW 537
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
WS CS CGK G R+R+ + + G D E DL + + C +D
Sbjct: 538 --SEWSDCSVTCGK-GMRTRQRMLKSLAELG-----DCNE--DLEQVEKCMLPECPIDCE 587
Query: 450 CPTWFISPWKPCDKLCGSGQQTR 472
W S W C+K CG G R
Sbjct: 588 LTEW--SQWSECNKSCGKGHVIR 608
>X06989-1|CAA30050.1| 751|Homo sapiens amyloid A4 protein protein.
Length = 751
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 68.5 bits (160), Expect = 2e-10
Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC-S 1815
E V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C S
Sbjct: 284 EEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
Query: 1816 EIQXXXXXXXXXVQP--QQPGPENSEFCF 1842
I V + PG EN F
Sbjct: 344 AIPTTAASTPDAVDKYLETPGDENEHAHF 372
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 61.3 bits (142), Expect = 4e-08
Identities = 27/71 (38%), Positives = 34/71 (47%)
Query: 1578 VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
V+ ++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 342
Query: 1638 PARTKDQCSLP 1648
A S P
Sbjct: 343 SAIPTTAASTP 353
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
Score = 56.4 bits (130), Expect = 1e-06
Identities = 24/56 (42%), Positives = 29/56 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC + GPCRA + ++YFD C F YGGC G N F T C VC + I
Sbjct: 290 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAI 345
Score = 54.0 bits (124), Expect = 6e-06
Identities = 26/71 (36%), Positives = 34/71 (47%)
Query: 1519 IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCV 1578
+ E + CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 342
Query: 1579 QPSPKDACKLP 1589
P A P
Sbjct: 343 SAIPTTAASTP 353
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>X06982-1|CAA30042.1| 62|Homo sapiens amyloid beta-protein protein.
Length = 62
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 4 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 56
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 6 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 56
Score = 64.5 bits (150), Expect = 4e-09
Identities = 23/55 (41%), Positives = 36/55 (65%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C
Sbjct: 2 VREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 56
Score = 59.7 bits (138), Expect = 1e-07
Identities = 24/57 (42%), Positives = 30/57 (52%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPA 1639
++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C A
Sbjct: 3 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSA 59
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 3 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 58
Score = 56.4 bits (130), Expect = 1e-06
Identities = 24/56 (42%), Positives = 29/56 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC + GPCRA + ++YFD C F YGGC G N F T C VC + I
Sbjct: 5 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAI 60
Score = 50.4 bits (115), Expect = 7e-05
Identities = 23/56 (41%), Positives = 29/56 (51%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSP 1582
CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC P
Sbjct: 6 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAIP 61
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 3 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 56
>X06981-1|CAA30041.1| 81|Homo sapiens protein ( Human mRNA fragment
for amyloid beta-protein (AP) insertion. ).
Length = 81
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 3 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 55
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 5 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 55
Score = 64.5 bits (150), Expect = 4e-09
Identities = 23/55 (41%), Positives = 36/55 (65%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C
Sbjct: 1 VREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 55
Score = 60.1 bits (139), Expect = 8e-08
Identities = 24/60 (40%), Positives = 32/60 (53%)
Query: 1583 KDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCEPARTK 1642
++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C A ++
Sbjct: 2 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQ 61
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 2 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 57
Score = 56.0 bits (129), Expect = 1e-06
Identities = 23/52 (44%), Positives = 27/52 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
VC + GPCRA + ++YFD C F YGGC G N F T C VC
Sbjct: 4 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 55
Score = 50.0 bits (114), Expect = 9e-05
Identities = 22/51 (43%), Positives = 28/51 (54%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC
Sbjct: 5 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 55
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 2 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 55
>M34875-1|AAB59501.1| 547|Homo sapiens amyloid-beta protein protein.
Length = 547
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 65.7 bits (153), Expect = 2e-09
Identities = 24/58 (41%), Positives = 37/58 (63%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
E V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C
Sbjct: 284 EEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/65 (38%), Positives = 34/65 (52%)
Query: 1578 VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
V+ ++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 342
Query: 1638 PARTK 1642
A ++
Sbjct: 343 SAMSQ 347
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
Score = 56.0 bits (129), Expect = 1e-06
Identities = 23/52 (44%), Positives = 27/52 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
VC + GPCRA + ++YFD C F YGGC G N F T C VC
Sbjct: 290 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 50.4 bits (115), Expect = 7e-05
Identities = 23/59 (38%), Positives = 31/59 (52%)
Query: 1519 IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+ E + CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>M33112-1|AAB59502.1| 770|Homo sapiens amyloid-beta protein protein.
Length = 770
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 65.7 bits (153), Expect = 2e-09
Identities = 24/58 (41%), Positives = 37/58 (63%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
E V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C
Sbjct: 284 EEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/65 (38%), Positives = 34/65 (52%)
Query: 1578 VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
V+ ++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 342
Query: 1638 PARTK 1642
A ++
Sbjct: 343 SAMSQ 347
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
Score = 56.0 bits (129), Expect = 1e-06
Identities = 23/52 (44%), Positives = 27/52 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
VC + GPCRA + ++YFD C F YGGC G N F T C VC
Sbjct: 290 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 50.4 bits (115), Expect = 7e-05
Identities = 23/59 (38%), Positives = 31/59 (52%)
Query: 1519 IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+ E + CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>M28373-1|AAA58727.1| 484|Homo sapiens amyloid precursor protein
protein.
Length = 484
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 210 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 262
Score = 68.5 bits (160), Expect = 2e-10
Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC-S 1815
E V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C S
Sbjct: 205 EEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 264
Query: 1816 EIQXXXXXXXXXVQP--QQPGPENSEFCF 1842
I V + PG EN F
Sbjct: 265 AIPTTAASTPDAVDKYLETPGDENEHAHF 293
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 212 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 262
Score = 61.3 bits (142), Expect = 4e-08
Identities = 27/71 (38%), Positives = 34/71 (47%)
Query: 1578 VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
V+ ++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C
Sbjct: 204 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 263
Query: 1638 PARTKDQCSLP 1648
A S P
Sbjct: 264 SAIPTTAASTP 274
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 209 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 264
Score = 56.4 bits (130), Expect = 1e-06
Identities = 24/56 (42%), Positives = 29/56 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC + GPCRA + ++YFD C F YGGC G N F T C VC + I
Sbjct: 211 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAI 266
Score = 54.0 bits (124), Expect = 6e-06
Identities = 26/71 (36%), Positives = 34/71 (47%)
Query: 1519 IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCV 1578
+ E + CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC
Sbjct: 204 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 263
Query: 1579 QPSPKDACKLP 1589
P A P
Sbjct: 264 SAIPTTAASTP 274
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 209 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 262
>D87675-1|BAA22264.1| 770|Homo sapiens amyloid precursor protein
protein.
Length = 770
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 65.7 bits (153), Expect = 2e-09
Identities = 24/58 (41%), Positives = 37/58 (63%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
E V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C
Sbjct: 284 EEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/65 (38%), Positives = 34/65 (52%)
Query: 1578 VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
V+ ++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 342
Query: 1638 PARTK 1642
A ++
Sbjct: 343 SAMSQ 347
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
Score = 56.0 bits (129), Expect = 1e-06
Identities = 23/52 (44%), Positives = 27/52 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
VC + GPCRA + ++YFD C F YGGC G N F T C VC
Sbjct: 290 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 50.4 bits (115), Expect = 7e-05
Identities = 23/59 (38%), Positives = 31/59 (52%)
Query: 1519 IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+ E + CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>BC065529-1|AAH65529.1| 751|Homo sapiens amyloid beta (A4) precursor
protein (peptidase nexin-II, Alzheimer disease) protein.
Length = 751
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 68.5 bits (160), Expect = 2e-10
Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC-S 1815
E V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C S
Sbjct: 284 EEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
Query: 1816 EIQXXXXXXXXXVQP--QQPGPENSEFCF 1842
I V + PG EN F
Sbjct: 344 AIPTTAASTPDAVDKYLETPGDENEHAHF 372
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 61.3 bits (142), Expect = 4e-08
Identities = 27/71 (38%), Positives = 34/71 (47%)
Query: 1578 VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
V+ ++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 342
Query: 1638 PARTKDQCSLP 1648
A S P
Sbjct: 343 SAIPTTAASTP 353
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
Score = 56.4 bits (130), Expect = 1e-06
Identities = 24/56 (42%), Positives = 29/56 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC + GPCRA + ++YFD C F YGGC G N F T C VC + I
Sbjct: 290 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAI 345
Score = 54.0 bits (124), Expect = 6e-06
Identities = 26/71 (36%), Positives = 34/71 (47%)
Query: 1519 IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCV 1578
+ E + CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 342
Query: 1579 QPSPKDACKLP 1589
P A P
Sbjct: 343 SAIPTTAASTP 353
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>AY919674-1|AAW82435.1| 770|Homo sapiens amyloid beta (A4) precursor
protein (protease nexin-II, Alzheimer disease) protein.
Length = 770
Score = 72.1 bits (169), Expect = 2e-11
Identities = 27/53 (50%), Positives = 34/53 (64%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 65.7 bits (153), Expect = 2e-09
Identities = 24/58 (41%), Positives = 37/58 (63%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
E V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C + C
Sbjct: 284 EEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 64.9 bits (151), Expect = 3e-09
Identities = 23/51 (45%), Positives = 31/51 (60%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C + C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/65 (38%), Positives = 34/65 (52%)
Query: 1578 VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
V+ ++ C G C RWY+D +C+ F YGGC GN NNFDT E C + C
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCG 342
Query: 1638 PARTK 1642
A ++
Sbjct: 343 SAMSQ 347
Score = 58.0 bits (134), Expect = 3e-07
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
++VC GPC I W++D + C+ F YGGCGGN N F + + C + C S
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGS 343
Score = 56.0 bits (129), Expect = 1e-06
Identities = 23/52 (44%), Positives = 27/52 (51%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
VC + GPCRA + ++YFD C F YGGC G N F T C VC
Sbjct: 290 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 50.4 bits (115), Expect = 7e-05
Identities = 23/59 (38%), Positives = 31/59 (52%)
Query: 1519 IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+ E + CS + G R WY+D+ G C+ F+YGG GN N F T+E C VC
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
Score = 48.8 bits (111), Expect = 2e-04
Identities = 20/54 (37%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
++ CS E G C RW F+ +C F +GGC GN N F +E C C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341
>L23982-1|AAA58965.1| 2912|Homo sapiens collagen type VII protein.
Length = 2912
Score = 71.7 bits (168), Expect = 3e-11
Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 1571 EECDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDS---EREQCSQFVYGGCLGNANNFD 1627
EE D D C LP +G+C Y +RWY+ + E C FVYGGC GNAN F
Sbjct: 2829 EEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFG 2888
Query: 1628 TRELCQSQCEPARTKDQ 1644
TRE C+ +C P + Q
Sbjct: 2889 TREACERRCPPRVVQSQ 2905
Score = 69.3 bits (162), Expect = 1e-10
Identities = 30/68 (44%), Positives = 41/68 (60%), Gaps = 4/68 (5%)
Query: 1638 PARTKDQCSLPIERGSCAGNFPRW---GFNDETQRCEEFIWGGCEGNSNRFGSEAACKQR 1694
P + D CSLP++ GSC RW T+ C F++GGC GN+NRFG+ AC++R
Sbjct: 2837 PWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERR 2896
Query: 1695 CDPPGTLQ 1702
C PP +Q
Sbjct: 2897 C-PPRVVQ 2903
Score = 64.9 bits (151), Expect = 3e-09
Identities = 27/58 (46%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDA---SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
+ D C LP+ G C + W++ A S +AC F YGGCGGN NRF +R+ CE RC
Sbjct: 2840 SDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2897
Score = 60.9 bits (141), Expect = 5e-08
Identities = 24/56 (42%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 1762 DLCTLPAETGECANYEEKWFYDT---SEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
D C+LP + G C Y +W++ S + C F YGGCGGN N+F ++ CE RC
Sbjct: 2842 DPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2897
Score = 56.8 bits (131), Expect = 8e-07
Identities = 26/65 (40%), Positives = 34/65 (52%), Gaps = 4/65 (6%)
Query: 1830 PQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGR---CAPFQYGGCGGNTNNFASEEH 1886
P+ P ++ + C D G CT + RW + A G C PF YGGCGGN N F + E
Sbjct: 2834 PEAPW-DSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREA 2892
Query: 1887 CQYYC 1891
C+ C
Sbjct: 2893 CERRC 2897
Score = 56.4 bits (130), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 1687 SEAACKQRCDP--PGTLQPRCSQPREQGGCNETAAVWWFSPAEGR---CRPFYYSGCGGN 1741
SE + ++ DP P CS P ++G C W+ G C PF Y GCGGN
Sbjct: 2824 SEYSVEEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGN 2883
Query: 1742 QNRFEDEAACASSCP 1756
NRF AC CP
Sbjct: 2884 ANRFGTREACERRCP 2898
Score = 51.6 bits (118), Expect = 3e-05
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGG---CSRFWYGGSDGNGNRFATKEECD 1574
+ P + CSL D GS Y++ WY+ G C F YGG GN NRF T+E C+
Sbjct: 2835 EAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACE 2894
Query: 1575 DVC 1577
C
Sbjct: 2895 RRC 2897
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 2046 CLYPLDPGPCRAYLPKYYF---DNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C PLD G C AY ++Y +C FVYGGC G NRF T C C
Sbjct: 2844 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2897
>L06862-1|AAA89196.1| 550|Homo sapiens type VII collagen protein.
Length = 550
Score = 71.7 bits (168), Expect = 3e-11
Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 1571 EECDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDS---EREQCSQFVYGGCLGNANNFD 1627
EE D D C LP +G+C Y +RWY+ + E C FVYGGC GNAN F
Sbjct: 467 EEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFG 526
Query: 1628 TRELCQSQCEPARTKDQ 1644
TRE C+ +C P + Q
Sbjct: 527 TREACERRCPPRVVQSQ 543
Score = 69.3 bits (162), Expect = 1e-10
Identities = 30/68 (44%), Positives = 41/68 (60%), Gaps = 4/68 (5%)
Query: 1638 PARTKDQCSLPIERGSCAGNFPRW---GFNDETQRCEEFIWGGCEGNSNRFGSEAACKQR 1694
P + D CSLP++ GSC RW T+ C F++GGC GN+NRFG+ AC++R
Sbjct: 475 PWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERR 534
Query: 1695 CDPPGTLQ 1702
C PP +Q
Sbjct: 535 C-PPRVVQ 541
Score = 64.9 bits (151), Expect = 3e-09
Identities = 27/58 (46%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDA---SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
+ D C LP+ G C + W++ A S +AC F YGGCGGN NRF +R+ CE RC
Sbjct: 478 SDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 535
Score = 60.9 bits (141), Expect = 5e-08
Identities = 24/56 (42%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 1762 DLCTLPAETGECANYEEKWFYDT---SEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
D C+LP + G C Y +W++ S + C F YGGCGGN N+F ++ CE RC
Sbjct: 480 DPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 535
Score = 56.8 bits (131), Expect = 8e-07
Identities = 26/65 (40%), Positives = 34/65 (52%), Gaps = 4/65 (6%)
Query: 1830 PQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGR---CAPFQYGGCGGNTNNFASEEH 1886
P+ P ++ + C D G CT + RW + A G C PF YGGCGGN N F + E
Sbjct: 472 PEAPW-DSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREA 530
Query: 1887 CQYYC 1891
C+ C
Sbjct: 531 CERRC 535
Score = 56.4 bits (130), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 1687 SEAACKQRCDP--PGTLQPRCSQPREQGGCNETAAVWWFSPAEGR---CRPFYYSGCGGN 1741
SE + ++ DP P CS P ++G C W+ G C PF Y GCGGN
Sbjct: 462 SEYSVEEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGN 521
Query: 1742 QNRFEDEAACASSCP 1756
NRF AC CP
Sbjct: 522 ANRFGTREACERRCP 536
Score = 51.6 bits (118), Expect = 3e-05
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGG---CSRFWYGGSDGNGNRFATKEECD 1574
+ P + CSL D GS Y++ WY+ G C F YGG GN NRF T+E C+
Sbjct: 473 EAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACE 532
Query: 1575 DVC 1577
C
Sbjct: 533 RRC 535
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 2046 CLYPLDPGPCRAYLPKYYF---DNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C PLD G C AY ++Y +C FVYGGC G NRF T C C
Sbjct: 482 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 535
>L02870-1|AAA75438.1| 2944|Homo sapiens alpha-1 type VII collagen
protein.
Length = 2944
Score = 71.7 bits (168), Expect = 3e-11
Identities = 33/77 (42%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 1571 EECDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDS---EREQCSQFVYGGCLGNANNFD 1627
EE D D C LP +G+C Y +RWY+ + E C FVYGGC GNAN F
Sbjct: 2861 EEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFG 2920
Query: 1628 TRELCQSQCEPARTKDQ 1644
TRE C+ +C P + Q
Sbjct: 2921 TREACERRCPPRVVQSQ 2937
Score = 69.3 bits (162), Expect = 1e-10
Identities = 30/68 (44%), Positives = 41/68 (60%), Gaps = 4/68 (5%)
Query: 1638 PARTKDQCSLPIERGSCAGNFPRW---GFNDETQRCEEFIWGGCEGNSNRFGSEAACKQR 1694
P + D CSLP++ GSC RW T+ C F++GGC GN+NRFG+ AC++R
Sbjct: 2869 PWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERR 2928
Query: 1695 CDPPGTLQ 1702
C PP +Q
Sbjct: 2929 C-PPRVVQ 2935
Score = 64.9 bits (151), Expect = 3e-09
Identities = 27/58 (46%), Positives = 35/58 (60%), Gaps = 3/58 (5%)
Query: 1894 TQDVCQLPMLAGPCNDSIVSWFYDA---SRDACSQFAYGGCGGNDNRFASRDECESRC 1948
+ D C LP+ G C + W++ A S +AC F YGGCGGN NRF +R+ CE RC
Sbjct: 2872 SDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
Score = 60.9 bits (141), Expect = 5e-08
Identities = 24/56 (42%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 1762 DLCTLPAETGECANYEEKWFYDT---SEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
D C+LP + G C Y +W++ S + C F YGGCGGN N+F ++ CE RC
Sbjct: 2874 DPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
Score = 56.8 bits (131), Expect = 8e-07
Identities = 26/65 (40%), Positives = 34/65 (52%), Gaps = 4/65 (6%)
Query: 1830 PQQPGPENSEFCFFETDPGPCTQFETRWSYDARGGR---CAPFQYGGCGGNTNNFASEEH 1886
P+ P ++ + C D G CT + RW + A G C PF YGGCGGN N F + E
Sbjct: 2866 PEAPW-DSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREA 2924
Query: 1887 CQYYC 1891
C+ C
Sbjct: 2925 CERRC 2929
Score = 56.4 bits (130), Expect = 1e-06
Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 1687 SEAACKQRCDP--PGTLQPRCSQPREQGGCNETAAVWWFSPAEGR---CRPFYYSGCGGN 1741
SE + ++ DP P CS P ++G C W+ G C PF Y GCGGN
Sbjct: 2856 SEYSVEEYQDPEAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGN 2915
Query: 1742 QNRFEDEAACASSCP 1756
NRF AC CP
Sbjct: 2916 ANRFGTREACERRCP 2930
Score = 51.6 bits (118), Expect = 3e-05
Identities = 25/63 (39%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGG---CSRFWYGGSDGNGNRFATKEECD 1574
+ P + CSL D GS Y++ WY+ G C F YGG GN NRF T+E C+
Sbjct: 2867 EAPWDSDDPCSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACE 2926
Query: 1575 DVC 1577
C
Sbjct: 2927 RRC 2929
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 3/54 (5%)
Query: 2046 CLYPLDPGPCRAYLPKYYF---DNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
C PLD G C AY ++Y +C FVYGGC G NRF T C C
Sbjct: 2876 CSLPLDEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRC 2929
>EF488667-1|ABP02055.1| 95|Homo sapiens TFPI2 variant protein.
Length = 95
Score = 71.7 bits (168), Expect = 3e-11
Identities = 27/52 (51%), Positives = 35/52 (67%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
+CL PLD GPCRA L +YY+D +SC++F+YGGC G N F T C + C
Sbjct: 6 ICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 57
Score = 62.1 bits (144), Expect = 2e-08
Identities = 26/53 (49%), Positives = 31/53 (58%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
+ C LP G C +R+YYD + C QF+YGGC GNANNF T E C C
Sbjct: 5 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 57
Score = 58.8 bits (136), Expect = 2e-07
Identities = 21/53 (39%), Positives = 32/53 (60%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRC 1948
++C LP+ GPC ++ ++YD +C QF YGGC GN N F + + C+ C
Sbjct: 5 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 57
Score = 56.4 bits (130), Expect = 1e-06
Identities = 22/57 (38%), Positives = 32/57 (56%)
Query: 1762 DLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRCSEIQ 1818
++C LP + G C +++YD + CRQF YGGC GN N F + C+ C I+
Sbjct: 5 EICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 61
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/55 (43%), Positives = 27/55 (49%)
Query: 1837 NSEFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
N+E C D GPC R+ YD C F YGGC GN NNF + E C C
Sbjct: 3 NAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 57
Score = 54.8 bits (126), Expect = 3e-06
Identities = 21/51 (41%), Positives = 31/51 (60%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
C LP++ G C R+ ++ TQ C +F++GGCEGN+N F + AC C
Sbjct: 7 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 57
Score = 54.0 bits (124), Expect = 6e-06
Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 5/73 (6%)
Query: 1522 NKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPS 1581
N C L D G R + +YYD C +F YGG +GN N F T E CDD C +
Sbjct: 2 NNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIE 61
Query: 1582 PKDACKLPKVKGA 1594
K+PKV+ A
Sbjct: 62 -----KVPKVESA 69
Score = 40.7 bits (91), Expect = 0.055
Identities = 17/51 (33%), Positives = 22/51 (43%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
C P + G C +++ CR F Y GC GN N F AC +C
Sbjct: 7 CLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDAC 57
>BC053369-1|AAH53369.1| 133|Homo sapiens serine peptidase
inhibitor-like, with Kunitz and WAP domains 1 (eppin)
protein.
Length = 133
Score = 71.7 bits (168), Expect = 3e-11
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ +D C++PK G C+ Y + W+YD + CS FVYGGC GN NNF ++ C
Sbjct: 65 CGKKCLDLK-QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 123
Query: 1633 QSQCEPAR 1640
+ C+ R
Sbjct: 124 LNTCKNKR 131
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/58 (44%), Positives = 36/58 (62%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGR 1952
QDVC++P GPC + W+YD + CS F YGGC GN+N F S+ C + C++ R
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKR 131
Score = 66.9 bits (156), Expect = 7e-10
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 1738 CGGNQNRFEDEAACASSCPEPFVP---DLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
C ++ +++ C SC + + D+C +P ETG C Y W+YD + C F Y
Sbjct: 48 CTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVY 107
Query: 1795 GGCGGNENKFNSQIECESRC 1814
GGC GN N F S+ C + C
Sbjct: 108 GGCQGNNNNFQSKANCLNTC 127
Score = 66.1 bits (154), Expect = 1e-09
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2032 ACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAE 2091
+C + C K +VC P + GPC AY +++D + +C FVYGGC G N F + A
Sbjct: 64 SCGKKCLDLKQ-DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKAN 122
Query: 2092 CTEVCKN 2098
C CKN
Sbjct: 123 CLNTCKN 129
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPA---RTKDQCSLPIERGSCAGNFPRWGFN 1664
RE+C C + D ++ C C +D C +P E G C F W ++
Sbjct: 37 REECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYD 96
Query: 1665 DETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+ C F++GGC+GN+N F S+A C C
Sbjct: 97 KKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 56.0 bits (129), Expect = 1e-06
Identities = 21/53 (39%), Positives = 28/53 (52%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
+ C + GPC + W YD + C+ F YGGC GN NNF S+ +C C
Sbjct: 75 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 55.6 bits (128), Expect = 2e-06
Identities = 21/60 (35%), Positives = 28/60 (46%)
Query: 1702 QPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
Q C P+E G C WW+ + C F Y GC GN N F+ +A C ++C P
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 133
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1516 CTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDD 1575
C D+ KQ C + K+ G Y ++W+YD + CS F YGG GN N F +K C +
Sbjct: 69 CLDL---KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLN 125
Query: 1576 VC 1577
C
Sbjct: 126 TC 127
>BC044829-1|AAH44829.2| 133|Homo sapiens serine peptidase
inhibitor-like, with Kunitz and WAP domains 1 (eppin)
protein.
Length = 133
Score = 71.7 bits (168), Expect = 3e-11
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ +D C++PK G C+ Y + W+YD + CS FVYGGC GN NNF ++ C
Sbjct: 65 CGKKCLDLK-QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 123
Query: 1633 QSQCEPAR 1640
+ C+ R
Sbjct: 124 LNTCKNKR 131
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/58 (44%), Positives = 36/58 (62%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGR 1952
QDVC++P GPC + W+YD + CS F YGGC GN+N F S+ C + C++ R
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKR 131
Score = 66.9 bits (156), Expect = 7e-10
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 1738 CGGNQNRFEDEAACASSCPEPFVP---DLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
C ++ +++ C SC + + D+C +P ETG C Y W+YD + C F Y
Sbjct: 48 CTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVY 107
Query: 1795 GGCGGNENKFNSQIECESRC 1814
GGC GN N F S+ C + C
Sbjct: 108 GGCQGNNNNFQSKANCLNTC 127
Score = 66.1 bits (154), Expect = 1e-09
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2032 ACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAE 2091
+C + C K +VC P + GPC AY +++D + +C FVYGGC G N F + A
Sbjct: 64 SCGKKCLDLKQ-DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKAN 122
Query: 2092 CTEVCKN 2098
C CKN
Sbjct: 123 CLNTCKN 129
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPA---RTKDQCSLPIERGSCAGNFPRWGFN 1664
RE+C C + D ++ C C +D C +P E G C F W ++
Sbjct: 37 REECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYD 96
Query: 1665 DETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+ C F++GGC+GN+N F S+A C C
Sbjct: 97 KKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 56.0 bits (129), Expect = 1e-06
Identities = 21/53 (39%), Positives = 28/53 (52%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
+ C + GPC + W YD + C+ F YGGC GN NNF S+ +C C
Sbjct: 75 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 55.6 bits (128), Expect = 2e-06
Identities = 21/60 (35%), Positives = 28/60 (46%)
Query: 1702 QPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
Q C P+E G C WW+ + C F Y GC GN N F+ +A C ++C P
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 133
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1516 CTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDD 1575
C D+ KQ C + K+ G Y ++W+YD + CS F YGG GN N F +K C +
Sbjct: 69 CLDL---KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLN 125
Query: 1576 VC 1577
C
Sbjct: 126 TC 127
>AL118493-1|CAB56343.1| 133|Homo sapiens hypothetical protein
protein.
Length = 133
Score = 71.7 bits (168), Expect = 3e-11
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ +D C++PK G C+ Y + W+YD + CS FVYGGC GN NNF ++ C
Sbjct: 65 CGKKCLDLK-QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 123
Query: 1633 QSQCEPAR 1640
+ C+ R
Sbjct: 124 LNTCKNKR 131
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/58 (44%), Positives = 36/58 (62%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGR 1952
QDVC++P GPC + W+YD + CS F YGGC GN+N F S+ C + C++ R
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKR 131
Score = 66.9 bits (156), Expect = 7e-10
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 1738 CGGNQNRFEDEAACASSCPEPFVP---DLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
C ++ +++ C SC + + D+C +P ETG C Y W+YD + C F Y
Sbjct: 48 CTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVY 107
Query: 1795 GGCGGNENKFNSQIECESRC 1814
GGC GN N F S+ C + C
Sbjct: 108 GGCQGNNNNFQSKANCLNTC 127
Score = 66.1 bits (154), Expect = 1e-09
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2032 ACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAE 2091
+C + C K +VC P + GPC AY +++D + +C FVYGGC G N F + A
Sbjct: 64 SCGKKCLDLKQ-DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKAN 122
Query: 2092 CTEVCKN 2098
C CKN
Sbjct: 123 CLNTCKN 129
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPA---RTKDQCSLPIERGSCAGNFPRWGFN 1664
RE+C C + D ++ C C +D C +P E G C F W ++
Sbjct: 37 REECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYD 96
Query: 1665 DETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+ C F++GGC+GN+N F S+A C C
Sbjct: 97 KKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 56.0 bits (129), Expect = 1e-06
Identities = 21/53 (39%), Positives = 28/53 (52%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
+ C + GPC + W YD + C+ F YGGC GN NNF S+ +C C
Sbjct: 75 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 55.6 bits (128), Expect = 2e-06
Identities = 21/60 (35%), Positives = 28/60 (46%)
Query: 1702 QPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
Q C P+E G C WW+ + C F Y GC GN N F+ +A C ++C P
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 133
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1516 CTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDD 1575
C D+ KQ C + K+ G Y ++W+YD + CS F YGG GN N F +K C +
Sbjct: 69 CLDL---KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLN 125
Query: 1576 VC 1577
C
Sbjct: 126 TC 127
>AL031663-12|CAB37635.1| 133|Homo sapiens serine peptidase
inhibitor-like, with Kunitz and WAP domains 1 (eppin)
protein.
Length = 133
Score = 71.7 bits (168), Expect = 3e-11
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ +D C++PK G C+ Y + W+YD + CS FVYGGC GN NNF ++ C
Sbjct: 65 CGKKCLDLK-QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 123
Query: 1633 QSQCEPAR 1640
+ C+ R
Sbjct: 124 LNTCKNKR 131
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/58 (44%), Positives = 36/58 (62%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGR 1952
QDVC++P GPC + W+YD + CS F YGGC GN+N F S+ C + C++ R
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKR 131
Score = 66.9 bits (156), Expect = 7e-10
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 1738 CGGNQNRFEDEAACASSCPEPFVP---DLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
C ++ +++ C SC + + D+C +P ETG C Y W+YD + C F Y
Sbjct: 48 CTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVY 107
Query: 1795 GGCGGNENKFNSQIECESRC 1814
GGC GN N F S+ C + C
Sbjct: 108 GGCQGNNNNFQSKANCLNTC 127
Score = 66.1 bits (154), Expect = 1e-09
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2032 ACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAE 2091
+C + C K +VC P + GPC AY +++D + +C FVYGGC G N F + A
Sbjct: 64 SCGKKCLDLKQ-DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKAN 122
Query: 2092 CTEVCKN 2098
C CKN
Sbjct: 123 CLNTCKN 129
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPA---RTKDQCSLPIERGSCAGNFPRWGFN 1664
RE+C C + D ++ C C +D C +P E G C F W ++
Sbjct: 37 REECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYD 96
Query: 1665 DETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+ C F++GGC+GN+N F S+A C C
Sbjct: 97 KKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 56.0 bits (129), Expect = 1e-06
Identities = 21/53 (39%), Positives = 28/53 (52%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
+ C + GPC + W YD + C+ F YGGC GN NNF S+ +C C
Sbjct: 75 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 55.6 bits (128), Expect = 2e-06
Identities = 21/60 (35%), Positives = 28/60 (46%)
Query: 1702 QPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
Q C P+E G C WW+ + C F Y GC GN N F+ +A C ++C P
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 133
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1516 CTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDD 1575
C D+ KQ C + K+ G Y ++W+YD + CS F YGG GN N F +K C +
Sbjct: 69 CLDL---KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLN 125
Query: 1576 VC 1577
C
Sbjct: 126 TC 127
>AL031663-11|CAC36265.1| 117|Homo sapiens serine peptidase
inhibitor-like, with Kunitz and WAP domains 1 (eppin)
protein.
Length = 117
Score = 71.7 bits (168), Expect = 3e-11
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ +D C++PK G C+ Y + W+YD + CS FVYGGC GN NNF ++ C
Sbjct: 49 CGKKCLDLK-QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 107
Query: 1633 QSQCEPAR 1640
+ C+ R
Sbjct: 108 LNTCKNKR 115
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/58 (44%), Positives = 36/58 (62%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGR 1952
QDVC++P GPC + W+YD + CS F YGGC GN+N F S+ C + C++ R
Sbjct: 58 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKR 115
Score = 66.9 bits (156), Expect = 7e-10
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 1738 CGGNQNRFEDEAACASSCPEPFVP---DLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
C ++ +++ C SC + + D+C +P ETG C Y W+YD + C F Y
Sbjct: 32 CTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVY 91
Query: 1795 GGCGGNENKFNSQIECESRC 1814
GGC GN N F S+ C + C
Sbjct: 92 GGCQGNNNNFQSKANCLNTC 111
Score = 66.1 bits (154), Expect = 1e-09
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2032 ACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAE 2091
+C + C K +VC P + GPC AY +++D + +C FVYGGC G N F + A
Sbjct: 48 SCGKKCLDLKQ-DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKAN 106
Query: 2092 CTEVCKN 2098
C CKN
Sbjct: 107 CLNTCKN 113
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPA---RTKDQCSLPIERGSCAGNFPRWGFN 1664
RE+C C + D ++ C C +D C +P E G C F W ++
Sbjct: 21 REECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYD 80
Query: 1665 DETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+ C F++GGC+GN+N F S+A C C
Sbjct: 81 KKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
Score = 56.0 bits (129), Expect = 1e-06
Identities = 21/53 (39%), Positives = 28/53 (52%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
+ C + GPC + W YD + C+ F YGGC GN NNF S+ +C C
Sbjct: 59 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
Score = 55.6 bits (128), Expect = 2e-06
Identities = 21/60 (35%), Positives = 28/60 (46%)
Query: 1702 QPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
Q C P+E G C WW+ + C F Y GC GN N F+ +A C ++C P
Sbjct: 58 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 117
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1516 CTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDD 1575
C D+ KQ C + K+ G Y ++W+YD + CS F YGG GN N F +K C +
Sbjct: 53 CLDL---KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLN 109
Query: 1576 VC 1577
C
Sbjct: 110 TC 111
>AF286370-1|AAG00548.1| 133|Homo sapiens eppin-3 protein.
Length = 133
Score = 71.7 bits (168), Expect = 3e-11
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ +D C++PK G C+ Y + W+YD + CS FVYGGC GN NNF ++ C
Sbjct: 65 CGKKCLDLK-QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 123
Query: 1633 QSQCEPAR 1640
+ C+ R
Sbjct: 124 LNTCKNKR 131
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/58 (44%), Positives = 36/58 (62%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGR 1952
QDVC++P GPC + W+YD + CS F YGGC GN+N F S+ C + C++ R
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKR 131
Score = 66.9 bits (156), Expect = 7e-10
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 1738 CGGNQNRFEDEAACASSCPEPFVP---DLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
C ++ +++ C SC + + D+C +P ETG C Y W+YD + C F Y
Sbjct: 48 CTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVY 107
Query: 1795 GGCGGNENKFNSQIECESRC 1814
GGC GN N F S+ C + C
Sbjct: 108 GGCQGNNNNFQSKANCLNTC 127
Score = 66.1 bits (154), Expect = 1e-09
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2032 ACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAE 2091
+C + C K +VC P + GPC AY +++D + +C FVYGGC G N F + A
Sbjct: 64 SCGKKCLDLKQ-DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKAN 122
Query: 2092 CTEVCKN 2098
C CKN
Sbjct: 123 CLNTCKN 129
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPA---RTKDQCSLPIERGSCAGNFPRWGFN 1664
RE+C C + D ++ C C +D C +P E G C F W ++
Sbjct: 37 REECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYD 96
Query: 1665 DETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+ C F++GGC+GN+N F S+A C C
Sbjct: 97 KKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 56.0 bits (129), Expect = 1e-06
Identities = 21/53 (39%), Positives = 28/53 (52%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
+ C + GPC + W YD + C+ F YGGC GN NNF S+ +C C
Sbjct: 75 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 55.6 bits (128), Expect = 2e-06
Identities = 21/60 (35%), Positives = 28/60 (46%)
Query: 1702 QPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
Q C P+E G C WW+ + C F Y GC GN N F+ +A C ++C P
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 133
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1516 CTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDD 1575
C D+ KQ C + K+ G Y ++W+YD + CS F YGG GN N F +K C +
Sbjct: 69 CLDL---KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLN 125
Query: 1576 VC 1577
C
Sbjct: 126 TC 127
>AF286369-1|AAG00547.1| 117|Homo sapiens eppin-2 protein.
Length = 117
Score = 71.7 bits (168), Expect = 3e-11
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ +D C++PK G C+ Y + W+YD + CS FVYGGC GN NNF ++ C
Sbjct: 49 CGKKCLDLK-QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 107
Query: 1633 QSQCEPAR 1640
+ C+ R
Sbjct: 108 LNTCKNKR 115
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/58 (44%), Positives = 36/58 (62%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGR 1952
QDVC++P GPC + W+YD + CS F YGGC GN+N F S+ C + C++ R
Sbjct: 58 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKR 115
Score = 66.9 bits (156), Expect = 7e-10
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 1738 CGGNQNRFEDEAACASSCPEPFVP---DLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
C ++ +++ C SC + + D+C +P ETG C Y W+YD + C F Y
Sbjct: 32 CTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVY 91
Query: 1795 GGCGGNENKFNSQIECESRC 1814
GGC GN N F S+ C + C
Sbjct: 92 GGCQGNNNNFQSKANCLNTC 111
Score = 66.1 bits (154), Expect = 1e-09
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2032 ACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAE 2091
+C + C K +VC P + GPC AY +++D + +C FVYGGC G N F + A
Sbjct: 48 SCGKKCLDLKQ-DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKAN 106
Query: 2092 CTEVCKN 2098
C CKN
Sbjct: 107 CLNTCKN 113
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPA---RTKDQCSLPIERGSCAGNFPRWGFN 1664
RE+C C + D ++ C C +D C +P E G C F W ++
Sbjct: 21 REECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYD 80
Query: 1665 DETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+ C F++GGC+GN+N F S+A C C
Sbjct: 81 KKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
Score = 56.0 bits (129), Expect = 1e-06
Identities = 21/53 (39%), Positives = 28/53 (52%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
+ C + GPC + W YD + C+ F YGGC GN NNF S+ +C C
Sbjct: 59 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 111
Score = 55.6 bits (128), Expect = 2e-06
Identities = 21/60 (35%), Positives = 28/60 (46%)
Query: 1702 QPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
Q C P+E G C WW+ + C F Y GC GN N F+ +A C ++C P
Sbjct: 58 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 117
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1516 CTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDD 1575
C D+ KQ C + K+ G Y ++W+YD + CS F YGG GN N F +K C +
Sbjct: 53 CLDL---KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLN 109
Query: 1576 VC 1577
C
Sbjct: 110 TC 111
>AF286368-1|AAG00546.1| 133|Homo sapiens eppin-1 protein.
Length = 133
Score = 71.7 bits (168), Expect = 3e-11
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 1/68 (1%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ +D C++PK G C+ Y + W+YD + CS FVYGGC GN NNF ++ C
Sbjct: 65 CGKKCLDLK-QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANC 123
Query: 1633 QSQCEPAR 1640
+ C+ R
Sbjct: 124 LNTCKNKR 131
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/58 (44%), Positives = 36/58 (62%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSGR 1952
QDVC++P GPC + W+YD + CS F YGGC GN+N F S+ C + C++ R
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKR 131
Score = 66.9 bits (156), Expect = 7e-10
Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 3/80 (3%)
Query: 1738 CGGNQNRFEDEAACASSCPEPFVP---DLCTLPAETGECANYEEKWFYDTSEKRCRQFYY 1794
C ++ +++ C SC + + D+C +P ETG C Y W+YD + C F Y
Sbjct: 48 CTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVY 107
Query: 1795 GGCGGNENKFNSQIECESRC 1814
GGC GN N F S+ C + C
Sbjct: 108 GGCQGNNNNFQSKANCLNTC 127
Score = 66.1 bits (154), Expect = 1e-09
Identities = 27/67 (40%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2032 ACERSCGAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAE 2091
+C + C K +VC P + GPC AY +++D + +C FVYGGC G N F + A
Sbjct: 64 SCGKKCLDLKQ-DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKAN 122
Query: 2092 CTEVCKN 2098
C CKN
Sbjct: 123 CLNTCKN 129
Score = 61.3 bits (142), Expect = 4e-08
Identities = 28/91 (30%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 1608 REQCSQFVYGGCLGNANNFDTRELCQSQCEPA---RTKDQCSLPIERGSCAGNFPRWGFN 1664
RE+C C + D ++ C C +D C +P E G C F W ++
Sbjct: 37 REECEFQERDVCTKDRQCQDNKKCCVFSCGKKCLDLKQDVCEMPKETGPCLAYFLHWWYD 96
Query: 1665 DETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+ C F++GGC+GN+N F S+A C C
Sbjct: 97 KKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 56.0 bits (129), Expect = 1e-06
Identities = 21/53 (39%), Positives = 28/53 (52%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
+ C + GPC + W YD + C+ F YGGC GN NNF S+ +C C
Sbjct: 75 DVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTC 127
Score = 55.6 bits (128), Expect = 2e-06
Identities = 21/60 (35%), Positives = 28/60 (46%)
Query: 1702 QPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
Q C P+E G C WW+ + C F Y GC GN N F+ +A C ++C P
Sbjct: 74 QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 133
Score = 55.2 bits (127), Expect = 2e-06
Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 1516 CTDIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDD 1575
C D+ KQ C + K+ G Y ++W+YD + CS F YGG GN N F +K C +
Sbjct: 69 CLDL---KQDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLN 125
Query: 1576 VC 1577
C
Sbjct: 126 TC 127
>X77166-1|CAA54410.1| 64|Homo sapiens Kunitz-type protease
inhibitor, HKIB9 protein.
Length = 64
Score = 71.3 bits (167), Expect = 3e-11
Identities = 26/54 (48%), Positives = 34/54 (62%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFT 1894
C F + GPC + TRW ++ G C F YGGCGGN+NNF +E C+ +C FT
Sbjct: 11 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCKFT 64
Score = 66.9 bits (156), Expect = 7e-10
Identities = 24/54 (44%), Positives = 32/54 (59%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCR 1949
+VC PM GPC + WF++ C FAYGGCGGN N F +++CE C+
Sbjct: 9 NVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 62
Score = 63.7 bits (148), Expect = 7e-09
Identities = 23/55 (41%), Positives = 31/55 (56%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
+P++C P E G C Y +WF++ C F YGGCGGN N F + +CE C
Sbjct: 7 LPNVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 61
Score = 63.7 bits (148), Expect = 7e-09
Identities = 22/54 (40%), Positives = 34/54 (62%)
Query: 2044 NVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
NVC +P++ GPC+ Y+ +++F+ E C+ F YGGC G N F +C + CK
Sbjct: 9 NVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 62
Score = 62.1 bits (144), Expect = 2e-08
Identities = 23/54 (42%), Positives = 32/54 (59%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
+ C P KG C Y RW+++ E +C F YGGC GN+NNF +E C+ C+
Sbjct: 9 NVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 62
Score = 60.1 bits (139), Expect = 8e-08
Identities = 24/51 (47%), Positives = 31/51 (60%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
C+ P+E+G C RW FN ET CE F +GGC GNSN F + C++ C
Sbjct: 11 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 61
Score = 52.8 bits (121), Expect = 1e-05
Identities = 19/51 (37%), Positives = 28/51 (54%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C+ ++G + Y W+++ E G C F YGG GN N F KE+C+ C
Sbjct: 11 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 61
Score = 50.4 bits (115), Expect = 7e-05
Identities = 20/51 (39%), Positives = 25/51 (49%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
C+ P E+G C W+F+ G C F Y GCGGN N F + C C
Sbjct: 11 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 61
>AL031663-6|CAB37639.3| 89|Homo sapiens serine peptidase inhibitor,
Kunitz type, 3 protein.
Length = 89
Score = 71.3 bits (167), Expect = 3e-11
Identities = 26/54 (48%), Positives = 34/54 (62%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFT 1894
C F + GPC + TRW ++ G C F YGGCGGN+NNF +E C+ +C FT
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCKFT 89
Score = 66.9 bits (156), Expect = 7e-10
Identities = 24/54 (44%), Positives = 32/54 (59%)
Query: 1896 DVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCR 1949
+VC PM GPC + WF++ C FAYGGCGGN N F +++CE C+
Sbjct: 34 NVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 87
Score = 63.7 bits (148), Expect = 7e-09
Identities = 23/55 (41%), Positives = 31/55 (56%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
+P++C P E G C Y +WF++ C F YGGCGGN N F + +CE C
Sbjct: 32 LPNVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
Score = 63.7 bits (148), Expect = 7e-09
Identities = 22/54 (40%), Positives = 34/54 (62%)
Query: 2044 NVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
NVC +P++ GPC+ Y+ +++F+ E C+ F YGGC G N F +C + CK
Sbjct: 34 NVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 87
Score = 62.1 bits (144), Expect = 2e-08
Identities = 23/54 (42%), Positives = 32/54 (59%)
Query: 1584 DACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
+ C P KG C Y RW+++ E +C F YGGC GN+NNF +E C+ C+
Sbjct: 34 NVCAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFCK 87
Score = 60.1 bits (139), Expect = 8e-08
Identities = 24/51 (47%), Positives = 31/51 (60%)
Query: 1645 CSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
C+ P+E+G C RW FN ET CE F +GGC GNSN F + C++ C
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
Score = 52.8 bits (121), Expect = 1e-05
Identities = 19/51 (37%), Positives = 28/51 (54%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
C+ ++G + Y W+++ E G C F YGG GN N F KE+C+ C
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
Score = 50.4 bits (115), Expect = 7e-05
Identities = 20/51 (39%), Positives = 25/51 (49%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
C+ P E+G C W+F+ G C F Y GCGGN N F + C C
Sbjct: 36 CAFPMEKGPCQTYMTRWFFNFETGECELFAYGGCGGNSNNFLRKEKCEKFC 86
>AK074803-1|BAC11217.1| 807|Homo sapiens protein ( Homo sapiens
cDNA FLJ90322 fis, clone NT2RP2001755, highly similar to
Rattus norvegicus f-spondin mRNA. ).
Length = 807
Score = 70.9 bits (166), Expect = 5e-11
Identities = 74/272 (27%), Positives = 109/272 (40%), Gaps = 43/272 (15%)
Query: 389 WVPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDA 448
W P WS CS G R R+ + + +P C D +P + C+ D
Sbjct: 448 WSP--WSACSSSTCDKGKRMRQRMLKAQLDLSVP-------CPDTQDFQPCMGPGCS-DE 497
Query: 449 ACPTWFISPW---KPCDKLCGSGQQTRQVVCYQ-KNNGRINVLSDDECSEEKPLDRQPCE 504
PT +S W PC CG G ++R+ Q +G + L +E EK + C
Sbjct: 498 DGPTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEET--EKCTVNEECS 555
Query: 505 LEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDK- 562
C +W EW TC ++ R + S C + A + +
Sbjct: 556 PSSCLMTEW--GEWDEYSATCGMGMKKRHRMIKMNP---ADGSMCKAETSQAEKRMMPEC 610
Query: 563 DKLPACQVQWYATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKP 622
+P W ++WS CSV CG G +TR+ S+ ++ D N E +
Sbjct: 611 HTIPCLLSPW--SEWSDCSVTCGKGMRTRQRML-----KSLAELGDCN----EDLEQVEK 659
Query: 623 CEVPEEKCP-----SKWYAAPWSECTKSCGKG 649
C +PE CP ++W + WSEC KSCGKG
Sbjct: 660 CMLPE--CPIDCELTEW--SQWSECNKSCGKG 687
Score = 65.3 bits (152), Expect = 2e-09
Identities = 98/384 (25%), Positives = 154/384 (40%), Gaps = 62/384 (16%)
Query: 336 FSSCSA-TCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPP----QWV 390
+S+CS+ TC G + R +++ +L V D +P C+ + P +W+
Sbjct: 451 WSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQD--FQPCMGPGCSDEDGPTCTMSEWI 508
Query: 391 PGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAAC 450
WS CS CG G RSRE ++ +G + +E K + E C+ +
Sbjct: 509 --TWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPTEET-----EKCTVNEECSPSSCL 560
Query: 451 PTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEG 510
T + W CG G + R + K N + E S+ + C PC
Sbjct: 561 MTEW-GEWDEYSATCGMGMKKRHRMI--KMNPADGSMCKAETSQAEKRMMPECHTIPCLL 617
Query: 511 VDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQ 569
W SEW+ C TC +R+R Q + K + C+ LE+ +K LP C
Sbjct: 618 SPW--SEWSDCSVTCGKGMRTR--QRMLKSLAELGD--CNED----LEQ-VEKCMLPECP 666
Query: 570 VQWYAT---QWSKCSVECGVGK--KTRRV-FCGKFDGASVMK-VDDSNC--------PKE 614
+ T QWS+C+ CG G +TR + +F GA + V C P
Sbjct: 667 IDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSI 726
Query: 615 EKY-----NDSKPCEVPEEKCPSKWYA-------APWSECTKSCGKGLRFRSVVCLRGGK 662
+K +S+ E +E+ + + WSECTK CG G++ R + + K
Sbjct: 727 QKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFK 786
Query: 663 --EFSDCPKKSLPDSAGSCNEQSC 684
+F+ C K +CN C
Sbjct: 787 SSQFTSCKDKK---EIRACNVHPC 807
Score = 49.2 bits (112), Expect = 2e-04
Identities = 59/222 (26%), Positives = 96/222 (43%), Gaps = 30/222 (13%)
Query: 456 SPWKPCDK-LCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPC---EGV 511
SPW C C G++ RQ + K ++V C + + D QPC C +G
Sbjct: 449 SPWSACSSSTCDKGKRMRQRML--KAQLDLSV----PCPDTQ--DFQPCMGPGCSDEDGP 500
Query: 512 DWMVSEWTGCDTCLAT--VRSRVAQCVTKDYRVVNSSFCSYHPTPALEE-PCDKDKLPAC 568
+SEW C + + R + K + + S C+ PT E+ +++ P+
Sbjct: 501 TCTMSEWITWSPCSISCGMGMRSRERYVKQFPE-DGSVCTL-PTEETEKCTVNEECSPSS 558
Query: 569 QVQWYATQWSKCSVECGVG--KKTRRVFCGKFDGASVMKVDDSNCPKEEKYN-DSKPCEV 625
+ +W + S CG+G K+ R + DG S+ K + S K + PC +
Sbjct: 559 CLMTEWGEWDEYSATCGMGMKKRHRMIKMNPADG-SMCKAETSQAEKRMMPECHTIPCLL 617
Query: 626 PEEKCPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDC 667
S W + WS+C+ +CGKG+R R + L+ E DC
Sbjct: 618 ------SPW--SEWSDCSVTCGKGMRTRQRM-LKSLAELGDC 650
Score = 47.2 bits (107), Expect = 6e-04
Identities = 41/143 (28%), Positives = 57/143 (39%), Gaps = 20/143 (13%)
Query: 334 GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ---TCNTQAC-PPQW 389
G + SATCG G++ R ++ D +C A + C+T C W
Sbjct: 565 GEWDEYSATCGMGMKKR----HRMIKMNPADGSMCKAETSQAEKRMMPECHTIPCLLSPW 620
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
WS CS CGK G R+R+ + + G D E DL + + C +D
Sbjct: 621 --SEWSDCSVTCGK-GMRTRQRMLKSLAELG-----DCNE--DLEQVEKCMLPECPIDCE 670
Query: 450 CPTWFISPWKPCDKLCGSGQQTR 472
W S W C+K CG G R
Sbjct: 671 LTEW--SQWSECNKSCGKGHVIR 691
>BC065523-1|AAH65523.1| 352|Homo sapiens APP protein protein.
Length = 352
Score = 69.7 bits (163), Expect = 1e-10
Identities = 26/49 (53%), Positives = 33/49 (67%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHC 1887
E C + + GPC +RW +D G+CAPF YGGCGGN NNF +EE+C
Sbjct: 289 EVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYC 337
Score = 63.7 bits (148), Expect = 7e-09
Identities = 23/54 (42%), Positives = 35/54 (64%)
Query: 1757 EPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIEC 1810
E V ++C+ AETG C +W++D +E +C F+YGGCGGN N F+++ C
Sbjct: 284 EEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYC 337
Score = 62.1 bits (144), Expect = 2e-08
Identities = 22/47 (46%), Positives = 29/47 (61%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAAC 1751
CS+ E G C + W+F EG+C PF+Y GCGGN+N F+ E C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYC 337
Score = 56.8 bits (131), Expect = 8e-07
Identities = 23/57 (40%), Positives = 30/57 (52%)
Query: 1578 VQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQS 1634
V+ ++ C G C RWY+D +C+ F YGGC GN NNFDT E C +
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMA 339
Score = 55.2 bits (127), Expect = 2e-06
Identities = 20/50 (40%), Positives = 28/50 (56%)
Query: 1895 QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDEC 1944
++VC GPC I W++D + C+ F YGGCGGN N F + + C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYC 337
Score = 52.8 bits (121), Expect = 1e-05
Identities = 22/55 (40%), Positives = 28/55 (50%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNY 2099
VC + GPCRA + ++YFD C F YGGC G N F T C V + +
Sbjct: 290 VCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVWQRH 344
Score = 47.2 bits (107), Expect = 6e-04
Identities = 21/55 (38%), Positives = 29/55 (52%)
Query: 1519 IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEEC 1573
+ E + CS + G R WY+D+ G C+ F+YGG GN N F T+E C
Sbjct: 283 VEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYC 337
Score = 47.2 bits (107), Expect = 6e-04
Identities = 19/50 (38%), Positives = 25/50 (50%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAAC 1691
++ CS E G C RW F+ +C F +GGC GN N F +E C
Sbjct: 288 REVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYC 337
>AB005297-1|BAA23647.1| 1584|Homo sapiens BAI 1 protein.
Length = 1584
Score = 68.1 bits (159), Expect = 3e-10
Identities = 88/354 (24%), Positives = 130/354 (36%), Gaps = 54/354 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWS 395
+ C+ CGGG+Q+R TC +E G C+ L+ + CN +AC P G S
Sbjct: 270 WGECTRDCGGGLQTRTRTCLPAPGVE---GGGCEGVLEEG--RQCNREACGPA---GRTS 321
Query: 396 RCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFI 455
S+ R RE +++ G P+ P+ D A W
Sbjct: 322 SRSQSLRSTDARRREELGDELQQFGFPA------------PQTG-------DPAAEEW-- 360
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
SPW C CG G QTR C + + E++ + + P G
Sbjct: 361 SPWSVCSSTCGEGWQTRTRFCVSSS---YSTQCSGPLREQRLCNNS--AVCPVHGAWDEW 415
Query: 516 SEWTGC-DTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLP--ACQVQW 572
S W+ C TC R R C + + C P + C+ P A W
Sbjct: 416 SPWSLCSSTCGRGFRDRTRTCRPPQF---GGNPCE-GPEKQTKF-CNIALCPGRAVDGNW 470
Query: 573 YA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCP 631
+ WS CS C G++ R C +G S + C + + +++ C + +
Sbjct: 471 NEWSSWSACSASCSQGRQQRTREC---NGPS---YGGAEC--QGHWVETRDCFLQQCPVD 522
Query: 632 SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSC 684
KW A A W C+ +CG G + R VC G F + D C Q C
Sbjct: 523 GKWQAWASWGSCSVTCGAGSQRRERVC--SGPFFGGAACQGPQDEYRQCGTQRC 574
Score = 40.7 bits (91), Expect = 0.055
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 639 WSECTKSCGKGLRFRSVVCLRG-GKEFSDCPKKSLPDSAGSCNEQSCEALGEGSGYFTSL 697
W ECT+ CG GL+ R+ CL G E C + + + CN ++C G S SL
Sbjct: 270 WGECTRDCGGGLQTRTRTCLPAPGVEGGGC--EGVLEEGRQCNREACGPAGRTSSRSQSL 327
Score = 39.9 bits (89), Expect = 0.096
Identities = 20/45 (44%), Positives = 24/45 (53%), Gaps = 3/45 (6%)
Query: 58 CSRTCGGGVASQKRICLEIGPN-GEPQCTGGDTKYFSCETQDCPE 101
CS TCG G ++R+C GP G C G +Y C TQ CPE
Sbjct: 534 CSVTCGAGSQRRERVCS--GPFFGGAACQGPQDEYRQCGTQRCPE 576
>Z22572-1|CAA80295.1| 763|Homo sapiens CDEI binding protein protein.
Length = 763
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQL 1900
C E GPC RW +D G+C F YGGCGGN NNF SE++C C +
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK-----AMI 364
Query: 1901 PMLAGPCNDSIVSWFYDASRD 1921
P P ND V +++ S D
Sbjct: 365 PPTPLPTND--VDVYFETSAD 383
Score = 64.5 bits (150), Expect = 4e-09
Identities = 24/59 (40%), Positives = 34/59 (57%)
Query: 1892 HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
H + VC + GPC + W++D S+ C +F YGGCGGN N F S D C + C++
Sbjct: 304 HDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKA 362
Score = 60.9 bits (141), Expect = 5e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC GPCRA +P++YFD + C F+YGGC G N F + C VCK I
Sbjct: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
Score = 60.1 bits (139), Expect = 8e-08
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
+YYD G G+ + KE DV K C + G C RW
Sbjct: 273 YYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDV------KAVCSQEAMTGPCRAVMPRW 326
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
Y+D + +C +F+YGGC GN NNF++ + C + C+
Sbjct: 327 YFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
Score = 59.3 bits (137), Expect = 1e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V +C+ A TG C +W++D S+ +C +F YGGCGGN N F S+ C + C
Sbjct: 306 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 56.8 bits (131), Expect = 8e-07
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
CSQ G C W+F ++G+C F Y GCGGN+N FE E C + C P
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPP 366
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
K CS G C PRW F+ +C FI+GGC GN N F SE C C
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+I + + CS G R WY+D+ G C RF YGG GN N F +++ C VC
Sbjct: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Query: 1578 ---VQPSP 1582
+ P+P
Sbjct: 361 KAMIPPTP 368
>S60099-1|AAC60589.1| 763|Homo sapiens APPH protein.
Length = 763
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQL 1900
C E GPC RW +D G+C F YGGCGGN NNF SE++C C +
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK-----AMI 364
Query: 1901 PMLAGPCNDSIVSWFYDASRD 1921
P P ND V +++ S D
Sbjct: 365 PPTPLPTND--VDVYFETSAD 383
Score = 64.5 bits (150), Expect = 4e-09
Identities = 24/59 (40%), Positives = 34/59 (57%)
Query: 1892 HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
H + VC + GPC + W++D S+ C +F YGGCGGN N F S D C + C++
Sbjct: 304 HDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKA 362
Score = 60.9 bits (141), Expect = 5e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC GPCRA +P++YFD + C F+YGGC G N F + C VCK I
Sbjct: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
Score = 60.1 bits (139), Expect = 8e-08
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
+YYD G G+ + KE DV K C + G C RW
Sbjct: 273 YYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDV------KAVCSQEAMTGPCRAVMPRW 326
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
Y+D + +C +F+YGGC GN NNF++ + C + C+
Sbjct: 327 YFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
Score = 59.3 bits (137), Expect = 1e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V +C+ A TG C +W++D S+ +C +F YGGCGGN N F S+ C + C
Sbjct: 306 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 56.8 bits (131), Expect = 8e-07
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
CSQ G C W+F ++G+C F Y GCGGN+N FE E C + C P
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPP 366
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
K CS G C PRW F+ +C FI+GGC GN N F SE C C
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+I + + CS G R WY+D+ G C RF YGG GN N F +++ C VC
Sbjct: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Query: 1578 ---VQPSP 1582
+ P+P
Sbjct: 361 KAMIPPTP 368
>L27631-1|AAC41701.1| 763|Homo sapiens amyloid precursor-like protein
2 protein.
Length = 763
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQL 1900
C E GPC RW +D G+C F YGGCGGN NNF SE++C C +
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK-----AMI 364
Query: 1901 PMLAGPCNDSIVSWFYDASRD 1921
P P ND V +++ S D
Sbjct: 365 PPTPLPTND--VDVYFETSAD 383
Score = 64.5 bits (150), Expect = 4e-09
Identities = 24/59 (40%), Positives = 34/59 (57%)
Query: 1892 HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
H + VC + GPC + W++D S+ C +F YGGCGGN N F S D C + C++
Sbjct: 304 HDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKA 362
Score = 60.9 bits (141), Expect = 5e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC GPCRA +P++YFD + C F+YGGC G N F + C VCK I
Sbjct: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
Score = 60.1 bits (139), Expect = 8e-08
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
+YYD G G+ + KE DV K C + G C RW
Sbjct: 273 YYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDV------KAVCSQEAMTGPCRAVMPRW 326
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
Y+D + +C +F+YGGC GN NNF++ + C + C+
Sbjct: 327 YFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
Score = 59.3 bits (137), Expect = 1e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V +C+ A TG C +W++D S+ +C +F YGGCGGN N F S+ C + C
Sbjct: 306 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 56.8 bits (131), Expect = 8e-07
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
CSQ G C W+F ++G+C F Y GCGGN+N FE E C + C P
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPP 366
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
K CS G C PRW F+ +C FI+GGC GN N F SE C C
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+I + + CS G R WY+D+ G C RF YGG GN N F +++ C VC
Sbjct: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Query: 1578 ---VQPSP 1582
+ P+P
Sbjct: 361 KAMIPPTP 368
>L23113-1|AAA36032.1| 523|Homo sapiens binding protein protein.
Length = 523
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQL 1900
C E GPC RW +D G+C F YGGCGGN NNF SE++C C +
Sbjct: 82 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK-----AMI 136
Query: 1901 PMLAGPCNDSIVSWFYDASRD 1921
P P ND V +++ S D
Sbjct: 137 PPTPLPTND--VDVYFETSAD 155
Score = 64.5 bits (150), Expect = 4e-09
Identities = 24/59 (40%), Positives = 34/59 (57%)
Query: 1892 HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
H + VC + GPC + W++D S+ C +F YGGCGGN N F S D C + C++
Sbjct: 76 HDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKA 134
Score = 60.9 bits (141), Expect = 5e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC GPCRA +P++YFD + C F+YGGC G N F + C VCK I
Sbjct: 81 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 136
Score = 60.1 bits (139), Expect = 8e-08
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
+YYD G G+ + KE DV K C + G C RW
Sbjct: 45 YYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDV------KAVCSQEAMTGPCRAVMPRW 98
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
Y+D + +C +F+YGGC GN NNF++ + C + C+
Sbjct: 99 YFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 133
Score = 59.3 bits (137), Expect = 1e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V +C+ A TG C +W++D S+ +C +F YGGCGGN N F S+ C + C
Sbjct: 78 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 132
Score = 56.8 bits (131), Expect = 8e-07
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
CSQ G C W+F ++G+C F Y GCGGN+N FE E C + C P
Sbjct: 82 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPP 138
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
K CS G C PRW F+ +C FI+GGC GN N F SE C C
Sbjct: 79 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 132
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+I + + CS G R WY+D+ G C RF YGG GN N F +++ C VC
Sbjct: 73 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 132
Query: 1578 ---VQPSP 1582
+ P+P
Sbjct: 133 KAMIPPTP 140
>L09209-1|AAA35526.1| 763|Homo sapiens amyloid protein protein.
Length = 763
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQL 1900
C E GPC RW +D G+C F YGGCGGN NNF SE++C C +
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK-----AMI 364
Query: 1901 PMLAGPCNDSIVSWFYDASRD 1921
P P ND V +++ S D
Sbjct: 365 PPTPLPTND--VDVYFETSAD 383
Score = 64.5 bits (150), Expect = 4e-09
Identities = 24/59 (40%), Positives = 34/59 (57%)
Query: 1892 HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
H + VC + GPC + W++D S+ C +F YGGCGGN N F S D C + C++
Sbjct: 304 HDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKA 362
Score = 60.9 bits (141), Expect = 5e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC GPCRA +P++YFD + C F+YGGC G N F + C VCK I
Sbjct: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
Score = 60.1 bits (139), Expect = 8e-08
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
+YYD G G+ + KE DV K C + G C RW
Sbjct: 273 YYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDV------KAVCSQEAMTGPCRAVMPRW 326
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
Y+D + +C +F+YGGC GN NNF++ + C + C+
Sbjct: 327 YFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
Score = 59.3 bits (137), Expect = 1e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V +C+ A TG C +W++D S+ +C +F YGGCGGN N F S+ C + C
Sbjct: 306 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 56.8 bits (131), Expect = 8e-07
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
CSQ G C W+F ++G+C F Y GCGGN+N FE E C + C P
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPP 366
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
K CS G C PRW F+ +C FI+GGC GN N F SE C C
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+I + + CS G R WY+D+ G C RF YGG GN N F +++ C VC
Sbjct: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Query: 1578 ---VQPSP 1582
+ P+P
Sbjct: 361 KAMIPPTP 368
>BC000373-1|AAH00373.1| 751|Homo sapiens APLP2 protein protein.
Length = 751
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQL 1900
C E GPC RW +D G+C F YGGCGGN NNF SE++C C +
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK-----AMI 364
Query: 1901 PMLAGPCNDSIVSWFYDASRD 1921
P P ND V +++ S D
Sbjct: 365 PPTPLPTND--VDVYFETSAD 383
Score = 64.5 bits (150), Expect = 4e-09
Identities = 24/59 (40%), Positives = 34/59 (57%)
Query: 1892 HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
H + VC + GPC + W++D S+ C +F YGGCGGN N F S D C + C++
Sbjct: 304 HDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKA 362
Score = 60.9 bits (141), Expect = 5e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC GPCRA +P++YFD + C F+YGGC G N F + C VCK I
Sbjct: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
Score = 60.1 bits (139), Expect = 8e-08
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
+YYD G G+ + KE DV K C + G C RW
Sbjct: 273 YYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDV------KAVCSQEAMTGPCRAVMPRW 326
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
Y+D + +C +F+YGGC GN NNF++ + C + C+
Sbjct: 327 YFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
Score = 59.3 bits (137), Expect = 1e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V +C+ A TG C +W++D S+ +C +F YGGCGGN N F S+ C + C
Sbjct: 306 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 56.8 bits (131), Expect = 8e-07
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
CSQ G C W+F ++G+C F Y GCGGN+N FE E C + C P
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPP 366
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
K CS G C PRW F+ +C FI+GGC GN N F SE C C
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+I + + CS G R WY+D+ G C RF YGG GN N F +++ C VC
Sbjct: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Query: 1578 ---VQPSP 1582
+ P+P
Sbjct: 361 KAMIPPTP 368
>AF168956-1|AAD47291.1| 763|Homo sapiens amyloid precursor protein
homolog HSD-2 protein.
Length = 763
Score = 65.3 bits (152), Expect = 2e-09
Identities = 32/81 (39%), Positives = 40/81 (49%), Gaps = 7/81 (8%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVCQL 1900
C E GPC RW +D G+C F YGGCGGN NNF SE++C C +
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK-----AMI 364
Query: 1901 PMLAGPCNDSIVSWFYDASRD 1921
P P ND V +++ S D
Sbjct: 365 PPTPLPTND--VDVYFETSAD 383
Score = 64.5 bits (150), Expect = 4e-09
Identities = 24/59 (40%), Positives = 34/59 (57%)
Query: 1892 HFTQDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRS 1950
H + VC + GPC + W++D S+ C +F YGGCGGN N F S D C + C++
Sbjct: 304 HDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKA 362
Score = 60.9 bits (141), Expect = 5e-08
Identities = 25/56 (44%), Positives = 31/56 (55%)
Query: 2045 VCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCKNYI 2100
VC GPCRA +P++YFD + C F+YGGC G N F + C VCK I
Sbjct: 309 VCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMI 364
Score = 60.1 bits (139), Expect = 8e-08
Identities = 30/95 (31%), Positives = 44/95 (46%), Gaps = 6/95 (6%)
Query: 1543 WYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQPSPKDACKLPKVKGACVGYNVRW 1602
+YYD G G+ + KE DV K C + G C RW
Sbjct: 273 YYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDV------KAVCSQEAMTGPCRAVMPRW 326
Query: 1603 YYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
Y+D + +C +F+YGGC GN NNF++ + C + C+
Sbjct: 327 YFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCK 361
Score = 59.3 bits (137), Expect = 1e-07
Identities = 23/55 (41%), Positives = 33/55 (60%)
Query: 1760 VPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
V +C+ A TG C +W++D S+ +C +F YGGCGGN N F S+ C + C
Sbjct: 306 VKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 56.8 bits (131), Expect = 8e-07
Identities = 23/57 (40%), Positives = 29/57 (50%)
Query: 1705 CSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSCPEPFVP 1761
CSQ G C W+F ++G+C F Y GCGGN+N FE E C + C P
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPP 366
Score = 50.8 bits (116), Expect = 5e-05
Identities = 23/54 (42%), Positives = 26/54 (48%)
Query: 1642 KDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
K CS G C PRW F+ +C FI+GGC GN N F SE C C
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Score = 50.0 bits (114), Expect = 9e-05
Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 1518 DIPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
+I + + CS G R WY+D+ G C RF YGG GN N F +++ C VC
Sbjct: 301 EITHDVKAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVC 360
Query: 1578 ---VQPSP 1582
+ P+P
Sbjct: 361 KAMIPPTP 368
>AJ890451-1|CAI67595.1| 1125|Homo sapiens collagen, type XXVIII
protein.
Length = 1125
Score = 64.5 bits (150), Expect = 4e-09
Identities = 23/53 (43%), Positives = 35/53 (66%)
Query: 1527 CSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVCVQ 1579
C A G+ +Y V WYYD + C+RFW+ G +G+GNRF +++EC + C+Q
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQ 1124
Score = 58.4 bits (135), Expect = 3e-07
Identities = 22/51 (43%), Positives = 31/51 (60%)
Query: 2046 CLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVC 2096
CL L PG C Y+ ++Y+D + SC F + GC+G NRF++ EC E C
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
Score = 57.6 bits (133), Expect = 4e-07
Identities = 19/51 (37%), Positives = 29/51 (56%)
Query: 1764 CTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
C + G C Y +W+YD C +F++ GC G+ N+FNS+ EC+ C
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
Score = 56.0 bits (129), Expect = 1e-06
Identities = 20/54 (37%), Positives = 31/54 (57%)
Query: 1898 CQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECESRCRSG 1951
C + G C + +V W+YD ++C++F + GC G+ NRF S EC+ C G
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG 1125
Score = 54.8 bits (126), Expect = 3e-06
Identities = 20/57 (35%), Positives = 28/57 (49%)
Query: 1699 GTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
G PRC + + G C E W++ C F++SGC G+ NRF E C +C
Sbjct: 1066 GAEDPRCLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
Score = 54.0 bits (124), Expect = 6e-06
Identities = 21/51 (41%), Positives = 27/51 (52%)
Query: 1841 CFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYC 1891
C PG C ++ RW YD + CA F + GC G+ N F SE+ CQ C
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
Score = 52.8 bits (121), Expect = 1e-05
Identities = 19/44 (43%), Positives = 27/44 (61%)
Query: 1593 GACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQC 1636
G C Y VRWYYD + C++F + GC G+ N F++ + CQ C
Sbjct: 1079 GNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
Score = 48.0 bits (109), Expect = 4e-04
Identities = 17/52 (32%), Positives = 28/52 (53%)
Query: 1644 QCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
+C ++ G+C RW ++ + C F + GC G+ NRF SE C++ C
Sbjct: 1071 RCLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122
>AL354919-5|CAI16890.1| 1584|Homo sapiens brain-specific
angiogenesis inhibitor 2 protein.
Length = 1584
Score = 62.9 bits (146), Expect = 1e-08
Identities = 72/261 (27%), Positives = 96/261 (36%), Gaps = 35/261 (13%)
Query: 437 KPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
+P LY + D A W SPW C CG G Q R C G L E +
Sbjct: 299 EPGLYMAQTGDPAAEEW--SPWSVCSLTCGQGLQVRTRSCVSSPYG---TLCSGPLRETR 353
Query: 497 PLDRQ-PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTP 554
P + C P GV W+ C +C RSR+ CV + C P
Sbjct: 354 PCNNSATC---PVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQH---GGKACE---GP 404
Query: 555 ALE-EPCDKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP 612
L+ + C P + QW W CS C G + R C SV + C
Sbjct: 405 ELQTKLCSMAACPV-EGQWLEWGPWGPCSTSCANGTQQRSRKC------SVAGPAWATC- 456
Query: 613 KEEKYNDSKPCEVPEEKCP---SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCP 668
D++ C E CP SKW WS C+K+C G + R +C G + C
Sbjct: 457 -TGALTDTRECSNLE--CPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPC- 512
Query: 669 KKSLPDSAGSCNEQSCEALGE 689
+ + C+E+ C A E
Sbjct: 513 -EGTGEEVKPCSEKRCPAFHE 532
Score = 60.1 bits (139), Expect = 8e-08
Identities = 46/143 (32%), Positives = 61/143 (42%), Gaps = 16/143 (11%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNW 394
+S CS TCG G+Q R +C S + L + +P N TC +W G+W
Sbjct: 318 WSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRE--TRPCNNSATCPVHGVWEEW--GSW 373
Query: 395 SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKEC-FDLLGPKPALYESCNVDAACPTW 453
S CS+ CG+ G+RSR C +P K C L K +C V+ W
Sbjct: 374 SLCSRSCGR-GSRSRMRTC-------VPPQHGGKACEGPELQTKLCSMAACPVEGQWLEW 425
Query: 454 FISPWKPCDKLCGSGQQTRQVVC 476
PW PC C +G Q R C
Sbjct: 426 --GPWGPCSTSCANGTQQRSRKC 446
Score = 53.2 bits (122), Expect = 1e-05
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 27/193 (13%)
Query: 334 GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP--PQWVP 391
G++S CS +CG G +SR TC + G +G + T + C+ ACP QW+
Sbjct: 371 GSWSLCSRSCGRGSRSRMRTCVPPQH-----GGKACEGPELQT-KLCSMAACPVEGQWLE 424
Query: 392 -GNWSRCSKRCGKDGTRSREVRCE---KIITNGLPSVVDDKECFDLLGPKPALYESCNVD 447
G W CS C +GT+ R +C ++ D +EC +L P D
Sbjct: 425 WGPWGPCSTSCA-NGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPA--------TD 475
Query: 448 AACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCEL-- 505
+ W + W C K C +G Q R +C + G + E KP + C
Sbjct: 476 SKWGPW--NAWSLCSKTCDTGWQRRFRMC--QATGTQGYPCEGTGEEVKPCSEKRCPAFH 531
Query: 506 EPCEGVDWMVSEW 518
E C M+ W
Sbjct: 532 EMCRDEYVMLMTW 544
Score = 46.8 bits (106), Expect = 8e-04
Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 21/196 (10%)
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE-EPCDKDKLPACQVQWY 573
S W+ C TC ++ R CV+ Y + CS P E PC+ W
Sbjct: 316 SPWSVCSLTCGQGLQVRTRSCVSSPY----GTLCS---GPLRETRPCNNSATCPVHGVWE 368
Query: 574 AT-QWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
WS CS CG G ++R C C E +K C +
Sbjct: 369 EWGSWSLCSRSCGRGSRSRMRTCVPPQHGG------KACEGPEL--QTKLCSMAACPVEG 420
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+W PW C+ SC G + RS C G ++ C +L D+ C+ C A
Sbjct: 421 QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATC-TGALTDTR-ECSNLECPATDSKW 478
Query: 692 GYFTSLDLESTFPEIG 707
G + + L S + G
Sbjct: 479 GPWNAWSLCSKTCDTG 494
Score = 35.5 bits (78), Expect = 2.1
Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 1/44 (2%)
Query: 57 PCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCP 100
PCS +C G + R C GP CTG T C +CP
Sbjct: 430 PCSTSCANGTQQRSRKCSVAGP-AWATCTGALTDTRECSNLECP 472
>AL354919-2|CAM12875.1| 1554|Homo sapiens brain-specific
angiogenesis inhibitor 2 protein.
Length = 1554
Score = 62.9 bits (146), Expect = 1e-08
Identities = 72/261 (27%), Positives = 96/261 (36%), Gaps = 35/261 (13%)
Query: 437 KPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
+P LY + D A W SPW C CG G Q R C G L E +
Sbjct: 287 EPGLYMAQTGDPAAEEW--SPWSVCSLTCGQGLQVRTRSCVSSPYG---TLCSGPLRETR 341
Query: 497 PLDRQ-PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTP 554
P + C P GV W+ C +C RSR+ CV + C P
Sbjct: 342 PCNNSATC---PVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQH---GGKACE---GP 392
Query: 555 ALE-EPCDKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP 612
L+ + C P + QW W CS C G + R C SV + C
Sbjct: 393 ELQTKLCSMAACPV-EGQWLEWGPWGPCSTSCANGTQQRSRKC------SVAGPAWATC- 444
Query: 613 KEEKYNDSKPCEVPEEKCP---SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCP 668
D++ C E CP SKW WS C+K+C G + R +C G + C
Sbjct: 445 -TGALTDTRECSNLE--CPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPC- 500
Query: 669 KKSLPDSAGSCNEQSCEALGE 689
+ + C+E+ C A E
Sbjct: 501 -EGTGEEVKPCSEKRCPAFHE 520
Score = 60.1 bits (139), Expect = 8e-08
Identities = 46/143 (32%), Positives = 61/143 (42%), Gaps = 16/143 (11%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNW 394
+S CS TCG G+Q R +C S + L + +P N TC +W G+W
Sbjct: 306 WSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRE--TRPCNNSATCPVHGVWEEW--GSW 361
Query: 395 SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKEC-FDLLGPKPALYESCNVDAACPTW 453
S CS+ CG+ G+RSR C +P K C L K +C V+ W
Sbjct: 362 SLCSRSCGR-GSRSRMRTC-------VPPQHGGKACEGPELQTKLCSMAACPVEGQWLEW 413
Query: 454 FISPWKPCDKLCGSGQQTRQVVC 476
PW PC C +G Q R C
Sbjct: 414 --GPWGPCSTSCANGTQQRSRKC 434
Score = 53.2 bits (122), Expect = 1e-05
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 27/193 (13%)
Query: 334 GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP--PQWVP 391
G++S CS +CG G +SR TC + G +G + T + C+ ACP QW+
Sbjct: 359 GSWSLCSRSCGRGSRSRMRTCVPPQH-----GGKACEGPELQT-KLCSMAACPVEGQWLE 412
Query: 392 -GNWSRCSKRCGKDGTRSREVRCE---KIITNGLPSVVDDKECFDLLGPKPALYESCNVD 447
G W CS C +GT+ R +C ++ D +EC +L P D
Sbjct: 413 WGPWGPCSTSCA-NGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPA--------TD 463
Query: 448 AACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCEL-- 505
+ W + W C K C +G Q R +C + G + E KP + C
Sbjct: 464 SKWGPW--NAWSLCSKTCDTGWQRRFRMC--QATGTQGYPCEGTGEEVKPCSEKRCPAFH 519
Query: 506 EPCEGVDWMVSEW 518
E C M+ W
Sbjct: 520 EMCRDEYVMLMTW 532
Score = 46.8 bits (106), Expect = 8e-04
Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 21/196 (10%)
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE-EPCDKDKLPACQVQWY 573
S W+ C TC ++ R CV+ Y + CS P E PC+ W
Sbjct: 304 SPWSVCSLTCGQGLQVRTRSCVSSPY----GTLCS---GPLRETRPCNNSATCPVHGVWE 356
Query: 574 AT-QWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
WS CS CG G ++R C C E +K C +
Sbjct: 357 EWGSWSLCSRSCGRGSRSRMRTCVPPQHGG------KACEGPEL--QTKLCSMAACPVEG 408
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+W PW C+ SC G + RS C G ++ C +L D+ C+ C A
Sbjct: 409 QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATC-TGALTDTR-ECSNLECPATDSKW 466
Query: 692 GYFTSLDLESTFPEIG 707
G + + L S + G
Sbjct: 467 GPWNAWSLCSKTCDTG 482
Score = 35.5 bits (78), Expect = 2.1
Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 1/44 (2%)
Query: 57 PCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCP 100
PCS +C G + R C GP CTG T C +CP
Sbjct: 418 PCSTSCANGTQQRSRKCSVAGP-AWATCTGALTDTRECSNLECP 460
>AK128724-1|BAC87592.1| 160|Homo sapiens protein ( Homo sapiens
cDNA FLJ46891 fis, clone UTERU3018255. ).
Length = 160
Score = 62.9 bits (146), Expect = 1e-08
Identities = 35/111 (31%), Positives = 54/111 (48%), Gaps = 9/111 (8%)
Query: 339 CSATCGG---GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACPPQWVPGNWS 395
C+ C G +Q R V C++R+ + + E C +P + Q C ++AC W W+
Sbjct: 12 CNGPCIGPHLAVQHRQVFCQTRDGITLPSEQ-CSALPRPVSTQNCWSEACSVHWRVSLWT 70
Query: 396 RCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNV 446
C+ CG G +SR V C TN V + C GP+PA ++ CN+
Sbjct: 71 LCTATCGNYGFQSRRVECVHARTN---KAVPEHLC--SWGPRPANWQRCNI 116
Score = 44.8 bits (101), Expect = 0.003
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
Query: 409 REVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAACPTWFISPWKPCDKLCGS- 467
R+V C+ LPS ++C L P+P ++C +A W +S W C CG+
Sbjct: 26 RQVFCQTRDGITLPS----EQCSAL--PRPVSTQNCWSEACSVHWRVSLWTLCTATCGNY 79
Query: 468 GQQTRQVVCYQKNNGRINVLSDDECS-EEKPLDRQPCELEPCE 509
G Q+R+V C + + + CS +P + Q C + PCE
Sbjct: 80 GFQSRRVECVHARTNK--AVPEHLCSWGPRPANWQRCNITPCE 120
Score = 44.4 bits (100), Expect = 0.004
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYATQWSKCSVECG-V 586
V+ R C T+D + S CS P P + C + AC V W + W+ C+ CG
Sbjct: 23 VQHRQVFCQTRDGITLPSEQCSALPRPVSTQNCWSE---ACSVHWRVSLWTLCTATCGNY 79
Query: 587 GKKTRRVFC 595
G ++RRV C
Sbjct: 80 GFQSRRVEC 88
Score = 44.0 bits (99), Expect = 0.006
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 331 WVHGNFSSCSATCGG-GIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQAC 385
W ++ C+ATCG G QSR V C + V E LC G +PA Q CN C
Sbjct: 64 WRVSLWTLCTATCGNYGFQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNITPC 119
Score = 35.9 bits (79), Expect = 1.6
Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 10/100 (10%)
Query: 591 RRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKWYAAPWSECTKSCGK-G 649
R+VFC DG ++ S P+ ++ C E C W + W+ CT +CG G
Sbjct: 26 RQVFCQTRDGITLPSEQCSALPRPVS---TQNCW--SEACSVHWRVSLWTLCTATCGNYG 80
Query: 650 LRFRSVVCL--RGGKEFSD--CPKKSLPDSAGSCNEQSCE 685
+ R V C+ R K + C P + CN CE
Sbjct: 81 FQSRRVECVHARTNKAVPEHLCSWGPRPANWQRCNITPCE 120
>AB065648-1|BAC05874.1| 1573|Homo sapiens seven transmembrane helix
receptor protein.
Length = 1573
Score = 62.9 bits (146), Expect = 1e-08
Identities = 72/261 (27%), Positives = 96/261 (36%), Gaps = 35/261 (13%)
Query: 437 KPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
+P LY + D A W SPW C CG G Q R C G L E +
Sbjct: 287 EPGLYMAQTGDPAAEEW--SPWSVCSLTCGQGLQVRTRSCVSSPYG---TLCSGPLRETR 341
Query: 497 PLDRQ-PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTP 554
P + C P GV W+ C +C RSR+ CV + C P
Sbjct: 342 PCNNSATC---PVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQH---GGKACE---GP 392
Query: 555 ALE-EPCDKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP 612
L+ + C P + QW W CS C G + R C SV + C
Sbjct: 393 ELQTKLCSMAACPV-EGQWLEWGPWGPCSTSCANGTQQRSRKC------SVAGPAWATC- 444
Query: 613 KEEKYNDSKPCEVPEEKCP---SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCP 668
D++ C E CP SKW WS C+K+C G + R +C G + C
Sbjct: 445 -TGALTDTRECSNLE--CPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPC- 500
Query: 669 KKSLPDSAGSCNEQSCEALGE 689
+ + C+E+ C A E
Sbjct: 501 -EGTGEEVKPCSEKRCPAFHE 520
Score = 60.1 bits (139), Expect = 8e-08
Identities = 46/143 (32%), Positives = 61/143 (42%), Gaps = 16/143 (11%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNW 394
+S CS TCG G+Q R +C S + L + +P N TC +W G+W
Sbjct: 306 WSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRE--TRPCNNSATCPVHGVWEEW--GSW 361
Query: 395 SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKEC-FDLLGPKPALYESCNVDAACPTW 453
S CS+ CG+ G+RSR C +P K C L K +C V+ W
Sbjct: 362 SLCSRSCGR-GSRSRMRTC-------VPPQHGGKACEGPELQTKLCSMAACPVEGQWLEW 413
Query: 454 FISPWKPCDKLCGSGQQTRQVVC 476
PW PC C +G Q R C
Sbjct: 414 --GPWGPCSTSCANGTQQRSRKC 434
Score = 53.2 bits (122), Expect = 1e-05
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 27/193 (13%)
Query: 334 GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP--PQWVP 391
G++S CS +CG G +SR TC + G +G + T + C+ ACP QW+
Sbjct: 359 GSWSLCSRSCGRGSRSRMRTCVPPQH-----GGKACEGPELQT-KLCSMAACPVEGQWLE 412
Query: 392 -GNWSRCSKRCGKDGTRSREVRCE---KIITNGLPSVVDDKECFDLLGPKPALYESCNVD 447
G W CS C +GT+ R +C ++ D +EC +L P D
Sbjct: 413 WGPWGPCSTSCA-NGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPA--------TD 463
Query: 448 AACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCEL-- 505
+ W + W C K C +G Q R +C + G + E KP + C
Sbjct: 464 SKWGPW--NAWSLCSKTCDTGWQRRFRMC--QATGTQGYPCEGTGEEVKPCSEKRCPAFH 519
Query: 506 EPCEGVDWMVSEW 518
E C M+ W
Sbjct: 520 EMCRDEYVMLMTW 532
Score = 46.8 bits (106), Expect = 8e-04
Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 21/196 (10%)
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE-EPCDKDKLPACQVQWY 573
S W+ C TC ++ R CV+ Y + CS P E PC+ W
Sbjct: 304 SPWSVCSLTCGQGLQVRTRSCVSSPY----GTLCS---GPLRETRPCNNSATCPVHGVWE 356
Query: 574 AT-QWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
WS CS CG G ++R C C E +K C +
Sbjct: 357 EWGSWSLCSRSCGRGSRSRMRTCVPPQHGG------KACEGPEL--QTKLCSMAACPVEG 408
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+W PW C+ SC G + RS C G ++ C +L D+ C+ C A
Sbjct: 409 QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATC-TGALTDTR-ECSNLECPATDSKW 466
Query: 692 GYFTSLDLESTFPEIG 707
G + + L S + G
Sbjct: 467 GPWNAWSLCSKTCDTG 482
Score = 35.5 bits (78), Expect = 2.1
Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 1/44 (2%)
Query: 57 PCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCP 100
PCS +C G + R C GP CTG T C +CP
Sbjct: 418 PCSTSCANGTQQRSRKCSVAGP-AWATCTGALTDTRECSNLECP 460
>AB005298-1|BAA25362.1| 1572|Homo sapiens BAI 2 protein.
Length = 1572
Score = 62.9 bits (146), Expect = 1e-08
Identities = 72/261 (27%), Positives = 96/261 (36%), Gaps = 35/261 (13%)
Query: 437 KPALYESCNVDAACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEK 496
+P LY + D A W SPW C CG G Q R C G L E +
Sbjct: 287 EPGLYMAQTGDPAAEEW--SPWSVCSLTCGQGLQVRTRSCVSSPYG---TLCSGPLRETR 341
Query: 497 PLDRQ-PCELEPCEGVDWMVSEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTP 554
P + C P GV W+ C +C RSR+ CV + C P
Sbjct: 342 PCNNSATC---PVHGVWEEWGSWSLCSRSCGRGSRSRMRTCVPPQH---GGKACE---GP 392
Query: 555 ALE-EPCDKDKLPACQVQWYA-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP 612
L+ + C P + QW W CS C G + R C SV + C
Sbjct: 393 ELQTKLCSMAACPV-EGQWLEWGPWGPCSTSCANGTQQRSRKC------SVAGPAWATC- 444
Query: 613 KEEKYNDSKPCEVPEEKCP---SKWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCP 668
D++ C E CP SKW WS C+K+C G + R +C G + C
Sbjct: 445 -TGALTDTRECSNLE--CPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQATGTQGYPC- 500
Query: 669 KKSLPDSAGSCNEQSCEALGE 689
+ + C+E+ C A E
Sbjct: 501 -EGTGEEVKPCSEKRCPAFHE 520
Score = 60.1 bits (139), Expect = 8e-08
Identities = 46/143 (32%), Positives = 61/143 (42%), Gaps = 16/143 (11%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ-TCNTQACPPQWVPGNW 394
+S CS TCG G+Q R +C S + L + +P N TC +W G+W
Sbjct: 306 WSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRE--TRPCNNSATCPVHGVWEEW--GSW 361
Query: 395 SRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKEC-FDLLGPKPALYESCNVDAACPTW 453
S CS+ CG+ G+RSR C +P K C L K +C V+ W
Sbjct: 362 SLCSRSCGR-GSRSRMRTC-------VPPQHGGKACEGPELQTKLCSMAACPVEGQWLEW 413
Query: 454 FISPWKPCDKLCGSGQQTRQVVC 476
PW PC C +G Q R C
Sbjct: 414 --GPWGPCSTSCANGTQQRSRKC 434
Score = 53.2 bits (122), Expect = 1e-05
Identities = 53/193 (27%), Positives = 78/193 (40%), Gaps = 27/193 (13%)
Query: 334 GNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTCNTQACP--PQWVP 391
G++S CS +CG G +SR TC + G +G + T + C+ ACP QW+
Sbjct: 359 GSWSLCSRSCGRGSRSRMRTCVPPQH-----GGKACEGPELQT-KLCSMAACPVEGQWLE 412
Query: 392 -GNWSRCSKRCGKDGTRSREVRCE---KIITNGLPSVVDDKECFDLLGPKPALYESCNVD 447
G W CS C +GT+ R +C ++ D +EC +L P D
Sbjct: 413 WGPWGPCSTSCA-NGTQQRSRKCSVAGPAWATCTGALTDTRECSNLECPA--------TD 463
Query: 448 AACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCEL-- 505
+ W + W C K C +G Q R +C + G + E KP + C
Sbjct: 464 SKWGPW--NAWSLCSKTCDTGWQRRFRMC--QATGTQGYPCEGTGEEVKPCSEKRCPAFH 519
Query: 506 EPCEGVDWMVSEW 518
E C M+ W
Sbjct: 520 EMCRDEYVMLMTW 532
Score = 46.8 bits (106), Expect = 8e-04
Identities = 50/196 (25%), Positives = 71/196 (36%), Gaps = 21/196 (10%)
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE-EPCDKDKLPACQVQWY 573
S W+ C TC ++ R CV+ Y + CS P E PC+ W
Sbjct: 304 SPWSVCSLTCGQGLQVRTRSCVSSPY----GTLCS---GPLRETRPCNNSATCPVHGVWE 356
Query: 574 AT-QWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
WS CS CG G ++R C C E +K C +
Sbjct: 357 EWGSWSLCSRSCGRGSRSRMRTCVPPQHGG------KACEGPEL--QTKLCSMAACPVEG 408
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGEGS 691
+W PW C+ SC G + RS C G ++ C +L D+ C+ C A
Sbjct: 409 QWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWATC-TGALTDTR-ECSNLECPATDSKW 466
Query: 692 GYFTSLDLESTFPEIG 707
G + + L S + G
Sbjct: 467 GPWNAWSLCSKTCDTG 482
Score = 35.5 bits (78), Expect = 2.1
Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 1/44 (2%)
Query: 57 PCSRTCGGGVASQKRICLEIGPNGEPQCTGGDTKYFSCETQDCP 100
PCS +C G + R C GP CTG T C +CP
Sbjct: 418 PCSTSCANGTQQRSRKCSVAGP-AWATCTGALTDTRECSNLECP 460
>AL591715-1|CAC39449.1| 232|Homo sapiens hypothetical protein
protein.
Length = 232
Score = 62.5 bits (145), Expect = 2e-08
Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 1690 ACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEA 1749
AC+++C P Q C P G CN A W F RC PF Y GC GN N F +E
Sbjct: 73 ACQKKCMDP--FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 130
Query: 1750 ACASSC 1755
AC ++C
Sbjct: 131 ACRTAC 136
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 1632 CQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAAC 1691
CQ +C ++ C LP+ G+C RW F+ + RC F + GCEGN+N F +E AC
Sbjct: 74 CQKKCMDP-FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 132
Query: 1692 KQRC 1695
+ C
Sbjct: 133 RTAC 136
Score = 60.1 bits (139), Expect = 8e-08
Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 1750 ACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIE 1809
AC C +PF + C LP G C + ++W +D RC F Y GC GN N F ++
Sbjct: 73 ACQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDA 131
Query: 1810 CESRC 1814
C + C
Sbjct: 132 CRTAC 136
Score = 60.1 bits (139), Expect = 8e-08
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ P ++ C LP G C RW++D + +C+ F Y GC GNANNF + C
Sbjct: 74 CQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 132
Query: 1633 QSQCEPARTKDQCSL-PI-ERGSC 1654
++ C QC L P ER C
Sbjct: 133 RTACMLIVKDGQCPLFPFTERKEC 156
Score = 56.8 bits (131), Expect = 8e-07
Identities = 24/64 (37%), Positives = 31/64 (48%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVC 1898
E C G C RW +D + RC PF+Y GC GN NNF +E+ C+ C
Sbjct: 84 EPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKDG 143
Query: 1899 QLPM 1902
Q P+
Sbjct: 144 QCPL 147
Score = 55.6 bits (128), Expect = 2e-06
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 1887 CQYYCHFT-QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
CQ C Q+ C LP+ G CN W +D C+ F Y GC GN N F + D C
Sbjct: 74 CQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACR 133
Query: 1946 SRC 1948
+ C
Sbjct: 134 TAC 136
Score = 43.2 bits (97), Expect = 0.010
Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 2032 ACERSC-GAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIA 2090
AC++ C F++ C+ P+ G C +++FD + C F Y GC G N F
Sbjct: 73 ACQKKCMDPFQE--PCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 130
Query: 2091 ECTEVC 2096
C C
Sbjct: 131 ACRTAC 136
Score = 40.3 bits (90), Expect = 0.073
Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 1/77 (1%)
Query: 1513 FFGCTD-IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKE 1571
FF C + Q C L G+ + W++D + C+ F Y G +GN N F ++
Sbjct: 71 FFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 130
Query: 1572 ECDDVCVQPSPKDACKL 1588
C C+ C L
Sbjct: 131 ACRTACMLIVKDGQCPL 147
>AL121778-2|CAI22977.1| 241|Homo sapiens WAP four-disulfide core
domain 8 protein.
Length = 241
Score = 62.5 bits (145), Expect = 2e-08
Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 1690 ACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEA 1749
AC+++C P Q C P G CN A W F RC PF Y GC GN N F +E
Sbjct: 82 ACQKKCMDP--FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 139
Query: 1750 ACASSC 1755
AC ++C
Sbjct: 140 ACRTAC 145
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 1632 CQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAAC 1691
CQ +C ++ C LP+ G+C RW F+ + RC F + GCEGN+N F +E AC
Sbjct: 83 CQKKCMDP-FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
Query: 1692 KQRC 1695
+ C
Sbjct: 142 RTAC 145
Score = 60.1 bits (139), Expect = 8e-08
Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 1750 ACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIE 1809
AC C +PF + C LP G C + ++W +D RC F Y GC GN N F ++
Sbjct: 82 ACQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDA 140
Query: 1810 CESRC 1814
C + C
Sbjct: 141 CRTAC 145
Score = 60.1 bits (139), Expect = 8e-08
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ P ++ C LP G C RW++D + +C+ F Y GC GNANNF + C
Sbjct: 83 CQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
Query: 1633 QSQCEPARTKDQCSL-PI-ERGSC 1654
++ C QC L P ER C
Sbjct: 142 RTACMLIVKDGQCPLFPFTERKEC 165
Score = 56.8 bits (131), Expect = 8e-07
Identities = 24/64 (37%), Positives = 31/64 (48%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVC 1898
E C G C RW +D + RC PF+Y GC GN NNF +E+ C+ C
Sbjct: 93 EPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKDG 152
Query: 1899 QLPM 1902
Q P+
Sbjct: 153 QCPL 156
Score = 55.6 bits (128), Expect = 2e-06
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 1887 CQYYCHFT-QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
CQ C Q+ C LP+ G CN W +D C+ F Y GC GN N F + D C
Sbjct: 83 CQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACR 142
Query: 1946 SRC 1948
+ C
Sbjct: 143 TAC 145
Score = 43.2 bits (97), Expect = 0.010
Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 2032 ACERSC-GAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIA 2090
AC++ C F++ C+ P+ G C +++FD + C F Y GC G N F
Sbjct: 82 ACQKKCMDPFQE--PCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 139
Query: 2091 ECTEVC 2096
C C
Sbjct: 140 ACRTAC 145
Score = 40.3 bits (90), Expect = 0.073
Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 1/77 (1%)
Query: 1513 FFGCTD-IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKE 1571
FF C + Q C L G+ + W++D + C+ F Y G +GN N F ++
Sbjct: 80 FFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 139
Query: 1572 ECDDVCVQPSPKDACKL 1588
C C+ C L
Sbjct: 140 ACRTACMLIVKDGQCPL 156
>AL031663-1|CAI21403.1| 241|Homo sapiens WAP four-disulfide core
domain 8 protein.
Length = 241
Score = 62.5 bits (145), Expect = 2e-08
Identities = 28/66 (42%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 1690 ACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEA 1749
AC+++C P Q C P G CN A W F RC PF Y GC GN N F +E
Sbjct: 82 ACQKKCMDP--FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 139
Query: 1750 ACASSC 1755
AC ++C
Sbjct: 140 ACRTAC 145
Score = 60.5 bits (140), Expect = 6e-08
Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 1632 CQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAAC 1691
CQ +C ++ C LP+ G+C RW F+ + RC F + GCEGN+N F +E AC
Sbjct: 83 CQKKCMDP-FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
Query: 1692 KQRC 1695
+ C
Sbjct: 142 RTAC 145
Score = 60.1 bits (139), Expect = 8e-08
Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 1750 ACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIE 1809
AC C +PF + C LP G C + ++W +D RC F Y GC GN N F ++
Sbjct: 82 ACQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDA 140
Query: 1810 CESRC 1814
C + C
Sbjct: 141 CRTAC 145
Score = 60.1 bits (139), Expect = 8e-08
Identities = 31/84 (36%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ P ++ C LP G C RW++D + +C+ F Y GC GNANNF + C
Sbjct: 83 CQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDAC 141
Query: 1633 QSQCEPARTKDQCSL-PI-ERGSC 1654
++ C QC L P ER C
Sbjct: 142 RTACMLIVKDGQCPLFPFTERKEC 165
Score = 56.8 bits (131), Expect = 8e-07
Identities = 24/64 (37%), Positives = 31/64 (48%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVC 1898
E C G C RW +D + RC PF+Y GC GN NNF +E+ C+ C
Sbjct: 93 EPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVKDG 152
Query: 1899 QLPM 1902
Q P+
Sbjct: 153 QCPL 156
Score = 55.6 bits (128), Expect = 2e-06
Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 1887 CQYYCHFT-QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
CQ C Q+ C LP+ G CN W +D C+ F Y GC GN N F + D C
Sbjct: 83 CQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACR 142
Query: 1946 SRC 1948
+ C
Sbjct: 143 TAC 145
Score = 43.2 bits (97), Expect = 0.010
Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 2032 ACERSC-GAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIA 2090
AC++ C F++ C+ P+ G C +++FD + C F Y GC G N F
Sbjct: 82 ACQKKCMDPFQE--PCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 139
Query: 2091 ECTEVC 2096
C C
Sbjct: 140 ACRTAC 145
Score = 40.3 bits (90), Expect = 0.073
Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 1/77 (1%)
Query: 1513 FFGCTD-IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKE 1571
FF C + Q C L G+ + W++D + C+ F Y G +GN N F ++
Sbjct: 80 FFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNED 139
Query: 1572 ECDDVCVQPSPKDACKL 1588
C C+ C L
Sbjct: 140 ACRTACMLIVKDGQCPL 156
>AF492016-1|AAN70998.1| 241|Homo sapiens probable protease inhibitor
splice variant WAP8b precursor protein.
Length = 241
Score = 62.1 bits (144), Expect = 2e-08
Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 1690 ACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEA 1749
AC+++C P Q C P G CN A W F RC PF Y GC GN N F E
Sbjct: 82 ACQKKCMDP--FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSED 139
Query: 1750 ACASSC 1755
AC ++C
Sbjct: 140 ACRTAC 145
Score = 61.7 bits (143), Expect = 3e-08
Identities = 26/64 (40%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 1632 CQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAAC 1691
CQ +C ++ C LP+ G+C RW F+ + RC F + GCEGN+N F SE AC
Sbjct: 83 CQKKCMDP-FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDAC 141
Query: 1692 KQRC 1695
+ C
Sbjct: 142 RTAC 145
Score = 61.3 bits (142), Expect = 4e-08
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 1750 ACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIE 1809
AC C +PF + C LP G C + ++W +D RC F Y GC GN N F S+
Sbjct: 82 ACQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDA 140
Query: 1810 CESRC 1814
C + C
Sbjct: 141 CRTAC 145
Score = 60.5 bits (140), Expect = 6e-08
Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ P ++ C LP G C RW++D + +C+ F Y GC GNANNF + + C
Sbjct: 83 CQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDAC 141
Query: 1633 QSQCEPARTKDQCSL-PI-ERGSC 1654
++ C QC L P ER C
Sbjct: 142 RTACMLIVKDGQCPLFPFTERKEC 165
Score = 58.0 bits (134), Expect = 3e-07
Identities = 25/64 (39%), Positives = 31/64 (48%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVC 1898
E C G C RW +D + RC PF+Y GC GN NNF SE+ C+ C
Sbjct: 93 EPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDACRTACMLIVKDG 152
Query: 1899 QLPM 1902
Q P+
Sbjct: 153 QCPL 156
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 1887 CQYYCHFT-QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
CQ C Q+ C LP+ G CN W +D C+ F Y GC GN N F S D C
Sbjct: 83 CQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDACR 142
Query: 1946 SRC 1948
+ C
Sbjct: 143 TAC 145
Score = 43.6 bits (98), Expect = 0.008
Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 3/66 (4%)
Query: 2032 ACERSC-GAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIA 2090
AC++ C F++ C+ P+ G C +++FD + C F Y GC G N F +
Sbjct: 82 ACQKKCMDPFQE--PCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSED 139
Query: 2091 ECTEVC 2096
C C
Sbjct: 140 ACRTAC 145
Score = 40.7 bits (91), Expect = 0.055
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 1513 FFGCTD-IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKE 1571
FF C + Q C L G+ + W++D + C+ F Y G +GN N F +++
Sbjct: 80 FFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSED 139
Query: 1572 ECDDVCVQPSPKDACKL 1588
C C+ C L
Sbjct: 140 ACRTACMLIVKDGQCPL 156
>AF492015-1|AAN70997.1| 241|Homo sapiens probable protease inhibitor
splice variant WAP8a precursor protein.
Length = 241
Score = 62.1 bits (144), Expect = 2e-08
Identities = 28/66 (42%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 1690 ACKQRCDPPGTLQPRCSQPREQGGCNETAAVWWFSPAEGRCRPFYYSGCGGNQNRFEDEA 1749
AC+++C P Q C P G CN A W F RC PF Y GC GN N F E
Sbjct: 82 ACQKKCMDP--FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSED 139
Query: 1750 ACASSC 1755
AC ++C
Sbjct: 140 ACRTAC 145
Score = 61.7 bits (143), Expect = 3e-08
Identities = 26/64 (40%), Positives = 36/64 (56%), Gaps = 1/64 (1%)
Query: 1632 CQSQCEPARTKDQCSLPIERGSCAGNFPRWGFNDETQRCEEFIWGGCEGNSNRFGSEAAC 1691
CQ +C ++ C LP+ G+C RW F+ + RC F + GCEGN+N F SE AC
Sbjct: 83 CQKKCMDP-FQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDAC 141
Query: 1692 KQRC 1695
+ C
Sbjct: 142 RTAC 145
Score = 61.3 bits (142), Expect = 4e-08
Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 1750 ACASSCPEPFVPDLCTLPAETGECANYEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIE 1809
AC C +PF + C LP G C + ++W +D RC F Y GC GN N F S+
Sbjct: 82 ACQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDA 140
Query: 1810 CESRC 1814
C + C
Sbjct: 141 CRTAC 145
Score = 60.5 bits (140), Expect = 6e-08
Identities = 31/84 (36%), Positives = 43/84 (51%), Gaps = 3/84 (3%)
Query: 1573 CDDVCVQPSPKDACKLPKVKGACVGYNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELC 1632
C C+ P ++ C LP G C RW++D + +C+ F Y GC GNANNF + + C
Sbjct: 83 CQKKCMDPF-QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDAC 141
Query: 1633 QSQCEPARTKDQCSL-PI-ERGSC 1654
++ C QC L P ER C
Sbjct: 142 RTACMLIVKDGQCPLFPFTERKEC 165
Score = 58.0 bits (134), Expect = 3e-07
Identities = 25/64 (39%), Positives = 31/64 (48%)
Query: 1839 EFCFFETDPGPCTQFETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFTQDVC 1898
E C G C RW +D + RC PF+Y GC GN NNF SE+ C+ C
Sbjct: 93 EPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDACRTACMLIVKDG 152
Query: 1899 QLPM 1902
Q P+
Sbjct: 153 QCPL 156
Score = 56.8 bits (131), Expect = 8e-07
Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Query: 1887 CQYYCHFT-QDVCQLPMLAGPCNDSIVSWFYDASRDACSQFAYGGCGGNDNRFASRDECE 1945
CQ C Q+ C LP+ G CN W +D C+ F Y GC GN N F S D C
Sbjct: 83 CQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSEDACR 142
Query: 1946 SRC 1948
+ C
Sbjct: 143 TAC 145
Score = 43.6 bits (98), Expect = 0.008
Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 3/66 (4%)
Query: 2032 ACERSC-GAFKDINVCLYPLDPGPCRAYLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIA 2090
AC++ C F++ C+ P+ G C +++FD + C F Y GC G N F +
Sbjct: 82 ACQKKCMDPFQE--PCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSED 139
Query: 2091 ECTEVC 2096
C C
Sbjct: 140 ACRTAC 145
Score = 40.7 bits (91), Expect = 0.055
Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 1513 FFGCTD-IPENKQVACSLAKDRGSGRDYSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKE 1571
FF C + Q C L G+ + W++D + C+ F Y G +GN N F +++
Sbjct: 80 FFACQKKCMDPFQEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLSED 139
Query: 1572 ECDDVCVQPSPKDACKL 1588
C C+ C L
Sbjct: 140 ACRTACMLIVKDGQCPL 156
>AY372172-1|AAR17081.1| 69|Homo sapiens serine protease inhibitor
Kunitz type 1 protein.
Length = 69
Score = 59.3 bits (137), Expect = 1e-07
Identities = 21/42 (50%), Positives = 29/42 (69%)
Query: 1853 FETRWSYDARGGRCAPFQYGGCGGNTNNFASEEHCQYYCHFT 1894
+ TRW ++ G C F YGGCGGN+NNF+ +E C+ +C FT
Sbjct: 28 YMTRWFFNFETGECELFAYGGCGGNSNNFSRKEKCEKFCKFT 69
Score = 52.4 bits (120), Expect = 2e-05
Identities = 18/40 (45%), Positives = 26/40 (65%)
Query: 1598 YNVRWYYDSEREQCSQFVYGGCLGNANNFDTRELCQSQCE 1637
Y RW+++ E +C F YGGC GN+NNF +E C+ C+
Sbjct: 28 YMTRWFFNFETGECELFAYGGCGGNSNNFSRKEKCEKFCK 67
Score = 51.6 bits (118), Expect = 3e-05
Identities = 17/36 (47%), Positives = 24/36 (66%)
Query: 1914 WFYDASRDACSQFAYGGCGGNDNRFASRDECESRCR 1949
WF++ C FAYGGCGGN N F+ +++CE C+
Sbjct: 32 WFFNFETGECELFAYGGCGGNSNNFSRKEKCEKFCK 67
Score = 48.4 bits (110), Expect = 3e-04
Identities = 17/39 (43%), Positives = 23/39 (58%)
Query: 1776 YEEKWFYDTSEKRCRQFYYGGCGGNENKFNSQIECESRC 1814
Y +WF++ C F YGGCGGN N F+ + +CE C
Sbjct: 28 YMTRWFFNFETGECELFAYGGCGGNSNNFSRKEKCEKFC 66
Score = 48.4 bits (110), Expect = 3e-04
Identities = 19/36 (52%), Positives = 23/36 (63%)
Query: 1660 RWGFNDETQRCEEFIWGGCEGNSNRFGSEAACKQRC 1695
RW FN ET CE F +GGC GNSN F + C++ C
Sbjct: 31 RWFFNFETGECELFAYGGCGGNSNNFSRKEKCEKFC 66
Score = 48.0 bits (109), Expect = 4e-04
Identities = 17/39 (43%), Positives = 23/39 (58%)
Query: 1539 YSVYWYYDMEYGGCSRFWYGGSDGNGNRFATKEECDDVC 1577
Y W+++ E G C F YGG GN N F+ KE+C+ C
Sbjct: 28 YMTRWFFNFETGECELFAYGGCGGNSNNFSRKEKCEKFC 66
Score = 44.4 bits (100), Expect = 0.004
Identities = 16/40 (40%), Positives = 24/40 (60%)
Query: 2058 YLPKYYFDNERRSCQEFVYGGCHGGPNRFSTIAECTEVCK 2097
Y+ +++F+ E C+ F YGGC G N FS +C + CK
Sbjct: 28 YMTRWFFNFETGECELFAYGGCGGNSNNFSRKEKCEKFCK 67
Score = 41.5 bits (93), Expect = 0.032
Identities = 15/35 (42%), Positives = 18/35 (51%)
Query: 1721 WWFSPAEGRCRPFYYSGCGGNQNRFEDEAACASSC 1755
W+F+ G C F Y GCGGN N F + C C
Sbjct: 32 WFFNFETGECELFAYGGCGGNSNNFSRKEKCEKFC 66
>L12350-1|AAA03703.1| 1172|Homo sapiens thrombospondin 2 protein.
Length = 1172
Score = 58.8 bits (136), Expect = 2e-07
Identities = 51/179 (28%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE-EPCD-KDKLPACQVQW 572
+EWT C TC + + R C + S T A CD + + W
Sbjct: 388 AEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSI----QTRACSLSKCDTRIRQDGGWSHW 443
Query: 573 YATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP---KEEKYNDSKPCEVPEEK 629
+ WS CSV CGVG TR C + V ++ NC +E K PC +
Sbjct: 444 --SPWSSCSVTCGVGNITRIRLCN----SPVPQMGGKNCKGSGRETKACQGAPCPIDGRW 497
Query: 630 CPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALG 688
P W +PWS CT +C G+R R+ VC ++ CN++SC G
Sbjct: 498 SP--W--SPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDG 552
Score = 46.8 bits (106), Expect = 8e-04
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 19/152 (12%)
Query: 389 WVP-GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVD 447
W P W++CS CG GT+ R C+ L + + C L + + D
Sbjct: 384 WSPWAEWTQCSVTCGS-GTQQRGRSCDVTSNTCLGPSIQTRAC-SLSKCDTRIRQ----D 437
Query: 448 AACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEP 507
W SPW C CG G TR +C N + + C + + + C+ P
Sbjct: 438 GGWSHW--SPWSSCSVTCGVGNITRIRLC----NSPVPQMGGKNC-KGSGRETKACQGAP 490
Query: 508 CEGVD--WMV-SEWTGCD-TCLATVRSRVAQC 535
C +D W S W+ C TC +R R C
Sbjct: 491 CP-IDGRWSPWSPWSACTVTCAGGIRERTRVC 521
>BX322234-1|CAI23645.1| 1172|Homo sapiens thrombospondin 2 protein.
Length = 1172
Score = 58.8 bits (136), Expect = 2e-07
Identities = 51/179 (28%), Positives = 71/179 (39%), Gaps = 20/179 (11%)
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALE-EPCD-KDKLPACQVQW 572
+EWT C TC + + R C + S T A CD + + W
Sbjct: 388 AEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSI----QTRACSLSKCDTRIRQDGGWSHW 443
Query: 573 YATQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCP---KEEKYNDSKPCEVPEEK 629
+ WS CSV CGVG TR C + V ++ NC +E K PC +
Sbjct: 444 --SPWSSCSVTCGVGNITRIRLCN----SPVPQMGGKNCKGSGRETKACQGAPCPIDGRW 497
Query: 630 CPSKWYAAPWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALG 688
P W +PWS CT +C G+R R+ VC ++ CN++SC G
Sbjct: 498 SP--W--SPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDG 552
Score = 46.8 bits (106), Expect = 8e-04
Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 19/152 (12%)
Query: 389 WVP-GNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVD 447
W P W++CS CG GT+ R C+ L + + C L + + D
Sbjct: 384 WSPWAEWTQCSVTCGS-GTQQRGRSCDVTSNTCLGPSIQTRAC-SLSKCDTRIRQ----D 437
Query: 448 AACPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEP 507
W SPW C CG G TR +C N + + C + + + C+ P
Sbjct: 438 GGWSHW--SPWSSCSVTCGVGNITRIRLC----NSPVPQMGGKNC-KGSGRETKACQGAP 490
Query: 508 CEGVD--WMV-SEWTGCD-TCLATVRSRVAQC 535
C +D W S W+ C TC +R R C
Sbjct: 491 CP-IDGRWSPWSPWSACTVTCAGGIRERTRVC 521
>AL391807-1|CAI21673.1| 1522|Homo sapiens brain-specific
angiogenesis inhibitor 3 protein.
Length = 1522
Score = 58.4 bits (135), Expect = 3e-07
Identities = 62/234 (26%), Positives = 80/234 (34%), Gaps = 25/234 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W C CG G Q R C + E + + L P GV
Sbjct: 298 SQWSTCSVTCGQGSQVRTRTCVSPYGTHCS----GPLRESRVCNN--TALCPVHGVWEEW 351
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA 574
S W+ C TC R+R C Y C T +PC+ P QW
Sbjct: 352 SPWSLCSFTCGRGQRTRTRSCTPPQY---GGRPCEGPETH--HKPCNIALCPV-DGQWQE 405
Query: 575 -TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV C G + R C + S C + +S+ C PE +
Sbjct: 406 WSSWSQCSVTCSNGTQQRSRQC------TAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Query: 634 WYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
W WS C+KSC G R C C + + CNEQ C A
Sbjct: 458 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQC--EGTGEEVRRCNEQRCPA 509
Score = 55.6 bits (128), Expect = 2e-06
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 33/208 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACP-----PQW 389
+S+CS TCG G Q R TC S C L+ ++ C NT CP +W
Sbjct: 300 WSTCSVTCGQGSQVRTRTCVSPYGTH------CSGPLR--ESRVCNNTALCPVHGVWEEW 351
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
P WS CS CG+ G R+R C G P + KP C VD
Sbjct: 352 SP--WSLCSFTCGR-GQRTRTRSCTPPQYGGRPCEGPETH------HKPCNIALCPVDGQ 402
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
W S W C C +G Q R C +G EC R+ E
Sbjct: 403 WQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHG------GSECRGPWAESRECYNPECTA 454
Query: 510 GVDW-MVSEWTGCD-TCLATVRSRVAQC 535
W W+GC +C R+ C
Sbjct: 455 NGQWNQWGHWSGCSKSCDGGWERRIRTC 482
Score = 51.2 bits (117), Expect = 4e-05
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 24/228 (10%)
Query: 417 ITNGLPSVVDDKECFDLLGPKPA--LYES--CNVDAACPTWFI----SPWKPCDKLCGSG 468
+T G S V + C G + L ES CN A CP + SPW C CG G
Sbjct: 305 VTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRG 364
Query: 469 QQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLAT 527
Q+TR C G + + KP + C ++ + +W S W+ C TC
Sbjct: 365 QRTRTRSCTPPQYGGRPCEGPE--THHKPCNIALCPVDG-QWQEW--SSWSQCSVTCSNG 419
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA-TQWSKCSVECGV 586
+ R QC + S C P E C + A QW WS CS C
Sbjct: 420 TQQRSRQCTAAAH---GGSECR-GPWAESRE-CYNPECTA-NGQWNQWGHWSGCSKSCDG 473
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
G + R C GA + +E + + + C P E CP +
Sbjct: 474 GWERRIRTC---QGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDY 518
Score = 47.6 bits (108), Expect = 5e-04
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 515 VSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWY 573
V EW+ TC T + +Q T+ + CS P E C+ L W
Sbjct: 294 VEEWSQWSTCSVTC-GQGSQVRTRTCVSPYGTHCS---GPLRESRVCNNTALCPVHGVWE 349
Query: 574 A-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
+ WS CS CG G++TR C + + C E ++ KPC +
Sbjct: 350 EWSPWSLCSFTCGRGQRTRTRSC------TPPQYGGRPCEGPETHH--KPCNIALCPVDG 401
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+W + WS+C+ +C G + RS C S+C + + C C A G+
Sbjct: 402 QWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Score = 44.0 bits (99), Expect = 0.006
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 9/131 (6%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
I P+ Q W ++S CS TC G Q R C + G + + N
Sbjct: 394 IALCPVDGQWQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAES-RECYNP 450
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR-CEKIITNGLPSVVDDKECFDLLGPK 437
C QW G+WS CSK C DG R +R C+ + G +E +
Sbjct: 451 ECTANGQWNQW--GHWSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCNEQR 506
Query: 438 -PALYESCNVD 447
PA YE C D
Sbjct: 507 CPAPYEICPED 517
>AL359714-1|CAH71522.1| 1522|Homo sapiens brain-specific
angiogenesis inhibitor 3 protein.
Length = 1522
Score = 58.4 bits (135), Expect = 3e-07
Identities = 62/234 (26%), Positives = 80/234 (34%), Gaps = 25/234 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W C CG G Q R C + E + + L P GV
Sbjct: 298 SQWSTCSVTCGQGSQVRTRTCVSPYGTHCS----GPLRESRVCNN--TALCPVHGVWEEW 351
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA 574
S W+ C TC R+R C Y C T +PC+ P QW
Sbjct: 352 SPWSLCSFTCGRGQRTRTRSCTPPQY---GGRPCEGPETH--HKPCNIALCPV-DGQWQE 405
Query: 575 -TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV C G + R C + S C + +S+ C PE +
Sbjct: 406 WSSWSQCSVTCSNGTQQRSRQC------TAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Query: 634 WYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
W WS C+KSC G R C C + + CNEQ C A
Sbjct: 458 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQC--EGTGEEVRRCNEQRCPA 509
Score = 55.6 bits (128), Expect = 2e-06
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 33/208 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACP-----PQW 389
+S+CS TCG G Q R TC S C L+ ++ C NT CP +W
Sbjct: 300 WSTCSVTCGQGSQVRTRTCVSPYGTH------CSGPLR--ESRVCNNTALCPVHGVWEEW 351
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
P WS CS CG+ G R+R C G P + KP C VD
Sbjct: 352 SP--WSLCSFTCGR-GQRTRTRSCTPPQYGGRPCEGPETH------HKPCNIALCPVDGQ 402
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
W S W C C +G Q R C +G EC R+ E
Sbjct: 403 WQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHG------GSECRGPWAESRECYNPECTA 454
Query: 510 GVDW-MVSEWTGCD-TCLATVRSRVAQC 535
W W+GC +C R+ C
Sbjct: 455 NGQWNQWGHWSGCSKSCDGGWERRIRTC 482
Score = 51.2 bits (117), Expect = 4e-05
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 24/228 (10%)
Query: 417 ITNGLPSVVDDKECFDLLGPKPA--LYES--CNVDAACPTWFI----SPWKPCDKLCGSG 468
+T G S V + C G + L ES CN A CP + SPW C CG G
Sbjct: 305 VTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRG 364
Query: 469 QQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLAT 527
Q+TR C G + + KP + C ++ + +W S W+ C TC
Sbjct: 365 QRTRTRSCTPPQYGGRPCEGPE--THHKPCNIALCPVDG-QWQEW--SSWSQCSVTCSNG 419
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA-TQWSKCSVECGV 586
+ R QC + S C P E C + A QW WS CS C
Sbjct: 420 TQQRSRQCTAAAH---GGSECR-GPWAESRE-CYNPECTA-NGQWNQWGHWSGCSKSCDG 473
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
G + R C GA + +E + + + C P E CP +
Sbjct: 474 GWERRIRTC---QGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDY 518
Score = 47.6 bits (108), Expect = 5e-04
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 515 VSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWY 573
V EW+ TC T + +Q T+ + CS P E C+ L W
Sbjct: 294 VEEWSQWSTCSVTC-GQGSQVRTRTCVSPYGTHCS---GPLRESRVCNNTALCPVHGVWE 349
Query: 574 A-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
+ WS CS CG G++TR C + + C E ++ KPC +
Sbjct: 350 EWSPWSLCSFTCGRGQRTRTRSC------TPPQYGGRPCEGPETHH--KPCNIALCPVDG 401
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+W + WS+C+ +C G + RS C S+C + + C C A G+
Sbjct: 402 QWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Score = 44.0 bits (99), Expect = 0.006
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 9/131 (6%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
I P+ Q W ++S CS TC G Q R C + G + + N
Sbjct: 394 IALCPVDGQWQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAES-RECYNP 450
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR-CEKIITNGLPSVVDDKECFDLLGPK 437
C QW G+WS CSK C DG R +R C+ + G +E +
Sbjct: 451 ECTANGQWNQW--GHWSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCNEQR 506
Query: 438 -PALYESCNVD 447
PA YE C D
Sbjct: 507 CPAPYEICPED 517
>AL356117-1|CAH71772.1| 1522|Homo sapiens brain-specific
angiogenesis inhibitor 3 protein.
Length = 1522
Score = 58.4 bits (135), Expect = 3e-07
Identities = 62/234 (26%), Positives = 80/234 (34%), Gaps = 25/234 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W C CG G Q R C + E + + L P GV
Sbjct: 298 SQWSTCSVTCGQGSQVRTRTCVSPYGTHCS----GPLRESRVCNN--TALCPVHGVWEEW 351
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA 574
S W+ C TC R+R C Y C T +PC+ P QW
Sbjct: 352 SPWSLCSFTCGRGQRTRTRSCTPPQY---GGRPCEGPETH--HKPCNIALCPV-DGQWQE 405
Query: 575 -TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV C G + R C + S C + +S+ C PE +
Sbjct: 406 WSSWSQCSVTCSNGTQQRSRQC------TAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Query: 634 WYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
W WS C+KSC G R C C + + CNEQ C A
Sbjct: 458 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQC--EGTGEEVRRCNEQRCPA 509
Score = 55.6 bits (128), Expect = 2e-06
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 33/208 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACP-----PQW 389
+S+CS TCG G Q R TC S C L+ ++ C NT CP +W
Sbjct: 300 WSTCSVTCGQGSQVRTRTCVSPYGTH------CSGPLR--ESRVCNNTALCPVHGVWEEW 351
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
P WS CS CG+ G R+R C G P + KP C VD
Sbjct: 352 SP--WSLCSFTCGR-GQRTRTRSCTPPQYGGRPCEGPETH------HKPCNIALCPVDGQ 402
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
W S W C C +G Q R C +G EC R+ E
Sbjct: 403 WQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHG------GSECRGPWAESRECYNPECTA 454
Query: 510 GVDW-MVSEWTGCD-TCLATVRSRVAQC 535
W W+GC +C R+ C
Sbjct: 455 NGQWNQWGHWSGCSKSCDGGWERRIRTC 482
Score = 51.2 bits (117), Expect = 4e-05
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 24/228 (10%)
Query: 417 ITNGLPSVVDDKECFDLLGPKPA--LYES--CNVDAACPTWFI----SPWKPCDKLCGSG 468
+T G S V + C G + L ES CN A CP + SPW C CG G
Sbjct: 305 VTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRG 364
Query: 469 QQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLAT 527
Q+TR C G + + KP + C ++ + +W S W+ C TC
Sbjct: 365 QRTRTRSCTPPQYGGRPCEGPE--THHKPCNIALCPVDG-QWQEW--SSWSQCSVTCSNG 419
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA-TQWSKCSVECGV 586
+ R QC + S C P E C + A QW WS CS C
Sbjct: 420 TQQRSRQCTAAAH---GGSECR-GPWAESRE-CYNPECTA-NGQWNQWGHWSGCSKSCDG 473
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
G + R C GA + +E + + + C P E CP +
Sbjct: 474 GWERRIRTC---QGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDY 518
Score = 47.6 bits (108), Expect = 5e-04
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 515 VSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWY 573
V EW+ TC T + +Q T+ + CS P E C+ L W
Sbjct: 294 VEEWSQWSTCSVTC-GQGSQVRTRTCVSPYGTHCS---GPLRESRVCNNTALCPVHGVWE 349
Query: 574 A-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
+ WS CS CG G++TR C + + C E ++ KPC +
Sbjct: 350 EWSPWSLCSFTCGRGQRTRTRSC------TPPQYGGRPCEGPETHH--KPCNIALCPVDG 401
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+W + WS+C+ +C G + RS C S+C + + C C A G+
Sbjct: 402 QWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Score = 44.0 bits (99), Expect = 0.006
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 9/131 (6%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
I P+ Q W ++S CS TC G Q R C + G + + N
Sbjct: 394 IALCPVDGQWQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAES-RECYNP 450
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR-CEKIITNGLPSVVDDKECFDLLGPK 437
C QW G+WS CSK C DG R +R C+ + G +E +
Sbjct: 451 ECTANGQWNQW--GHWSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCNEQR 506
Query: 438 -PALYESCNVD 447
PA YE C D
Sbjct: 507 CPAPYEICPED 517
>AL160401-1|CAH73864.1| 1522|Homo sapiens brain-specific
angiogenesis inhibitor 3 protein.
Length = 1522
Score = 58.4 bits (135), Expect = 3e-07
Identities = 62/234 (26%), Positives = 80/234 (34%), Gaps = 25/234 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W C CG G Q R C + E + + L P GV
Sbjct: 298 SQWSTCSVTCGQGSQVRTRTCVSPYGTHCS----GPLRESRVCNN--TALCPVHGVWEEW 351
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA 574
S W+ C TC R+R C Y C T +PC+ P QW
Sbjct: 352 SPWSLCSFTCGRGQRTRTRSCTPPQY---GGRPCEGPETH--HKPCNIALCPV-DGQWQE 405
Query: 575 -TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV C G + R C + S C + +S+ C PE +
Sbjct: 406 WSSWSQCSVTCSNGTQQRSRQC------TAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Query: 634 WYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
W WS C+KSC G R C C + + CNEQ C A
Sbjct: 458 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQC--EGTGEEVRRCNEQRCPA 509
Score = 55.6 bits (128), Expect = 2e-06
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 33/208 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACP-----PQW 389
+S+CS TCG G Q R TC S C L+ ++ C NT CP +W
Sbjct: 300 WSTCSVTCGQGSQVRTRTCVSPYGTH------CSGPLR--ESRVCNNTALCPVHGVWEEW 351
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
P WS CS CG+ G R+R C G P + KP C VD
Sbjct: 352 SP--WSLCSFTCGR-GQRTRTRSCTPPQYGGRPCEGPETH------HKPCNIALCPVDGQ 402
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
W S W C C +G Q R C +G EC R+ E
Sbjct: 403 WQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHG------GSECRGPWAESRECYNPECTA 454
Query: 510 GVDW-MVSEWTGCD-TCLATVRSRVAQC 535
W W+GC +C R+ C
Sbjct: 455 NGQWNQWGHWSGCSKSCDGGWERRIRTC 482
Score = 51.2 bits (117), Expect = 4e-05
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 24/228 (10%)
Query: 417 ITNGLPSVVDDKECFDLLGPKPA--LYES--CNVDAACPTWFI----SPWKPCDKLCGSG 468
+T G S V + C G + L ES CN A CP + SPW C CG G
Sbjct: 305 VTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRG 364
Query: 469 QQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLAT 527
Q+TR C G + + KP + C ++ + +W S W+ C TC
Sbjct: 365 QRTRTRSCTPPQYGGRPCEGPE--THHKPCNIALCPVDG-QWQEW--SSWSQCSVTCSNG 419
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA-TQWSKCSVECGV 586
+ R QC + S C P E C + A QW WS CS C
Sbjct: 420 TQQRSRQCTAAAH---GGSECR-GPWAESRE-CYNPECTA-NGQWNQWGHWSGCSKSCDG 473
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
G + R C GA + +E + + + C P E CP +
Sbjct: 474 GWERRIRTC---QGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDY 518
Score = 47.6 bits (108), Expect = 5e-04
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 515 VSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWY 573
V EW+ TC T + +Q T+ + CS P E C+ L W
Sbjct: 294 VEEWSQWSTCSVTC-GQGSQVRTRTCVSPYGTHCS---GPLRESRVCNNTALCPVHGVWE 349
Query: 574 A-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
+ WS CS CG G++TR C + + C E ++ KPC +
Sbjct: 350 EWSPWSLCSFTCGRGQRTRTRSC------TPPQYGGRPCEGPETHH--KPCNIALCPVDG 401
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+W + WS+C+ +C G + RS C S+C + + C C A G+
Sbjct: 402 QWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Score = 44.0 bits (99), Expect = 0.006
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 9/131 (6%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
I P+ Q W ++S CS TC G Q R C + G + + N
Sbjct: 394 IALCPVDGQWQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAES-RECYNP 450
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR-CEKIITNGLPSVVDDKECFDLLGPK 437
C QW G+WS CSK C DG R +R C+ + G +E +
Sbjct: 451 ECTANGQWNQW--GHWSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCNEQR 506
Query: 438 -PALYESCNVD 447
PA YE C D
Sbjct: 507 CPAPYEICPED 517
>AL158051-1|CAI19625.1| 1522|Homo sapiens brain-specific
angiogenesis inhibitor 3 protein.
Length = 1522
Score = 58.4 bits (135), Expect = 3e-07
Identities = 62/234 (26%), Positives = 80/234 (34%), Gaps = 25/234 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W C CG G Q R C + E + + L P GV
Sbjct: 298 SQWSTCSVTCGQGSQVRTRTCVSPYGTHCS----GPLRESRVCNN--TALCPVHGVWEEW 351
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA 574
S W+ C TC R+R C Y C T +PC+ P QW
Sbjct: 352 SPWSLCSFTCGRGQRTRTRSCTPPQY---GGRPCEGPETH--HKPCNIALCPV-DGQWQE 405
Query: 575 -TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV C G + R C + S C + +S+ C PE +
Sbjct: 406 WSSWSQCSVTCSNGTQQRSRQC------TAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Query: 634 WYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
W WS C+KSC G R C C + + CNEQ C A
Sbjct: 458 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQC--EGTGEEVRRCNEQRCPA 509
Score = 55.6 bits (128), Expect = 2e-06
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 33/208 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACP-----PQW 389
+S+CS TCG G Q R TC S C L+ ++ C NT CP +W
Sbjct: 300 WSTCSVTCGQGSQVRTRTCVSPYGTH------CSGPLR--ESRVCNNTALCPVHGVWEEW 351
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
P WS CS CG+ G R+R C G P + KP C VD
Sbjct: 352 SP--WSLCSFTCGR-GQRTRTRSCTPPQYGGRPCEGPETH------HKPCNIALCPVDGQ 402
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
W S W C C +G Q R C +G EC R+ E
Sbjct: 403 WQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHG------GSECRGPWAESRECYNPECTA 454
Query: 510 GVDW-MVSEWTGCD-TCLATVRSRVAQC 535
W W+GC +C R+ C
Sbjct: 455 NGQWNQWGHWSGCSKSCDGGWERRIRTC 482
Score = 51.2 bits (117), Expect = 4e-05
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 24/228 (10%)
Query: 417 ITNGLPSVVDDKECFDLLGPKPA--LYES--CNVDAACPTWFI----SPWKPCDKLCGSG 468
+T G S V + C G + L ES CN A CP + SPW C CG G
Sbjct: 305 VTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRG 364
Query: 469 QQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLAT 527
Q+TR C G + + KP + C ++ + +W S W+ C TC
Sbjct: 365 QRTRTRSCTPPQYGGRPCEGPE--THHKPCNIALCPVDG-QWQEW--SSWSQCSVTCSNG 419
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA-TQWSKCSVECGV 586
+ R QC + S C P E C + A QW WS CS C
Sbjct: 420 TQQRSRQCTAAAH---GGSECR-GPWAESRE-CYNPECTA-NGQWNQWGHWSGCSKSCDG 473
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
G + R C GA + +E + + + C P E CP +
Sbjct: 474 GWERRIRTC---QGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDY 518
Score = 47.6 bits (108), Expect = 5e-04
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 515 VSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWY 573
V EW+ TC T + +Q T+ + CS P E C+ L W
Sbjct: 294 VEEWSQWSTCSVTC-GQGSQVRTRTCVSPYGTHCS---GPLRESRVCNNTALCPVHGVWE 349
Query: 574 A-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
+ WS CS CG G++TR C + + C E ++ KPC +
Sbjct: 350 EWSPWSLCSFTCGRGQRTRTRSC------TPPQYGGRPCEGPETHH--KPCNIALCPVDG 401
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+W + WS+C+ +C G + RS C S+C + + C C A G+
Sbjct: 402 QWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Score = 44.0 bits (99), Expect = 0.006
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 9/131 (6%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
I P+ Q W ++S CS TC G Q R C + G + + N
Sbjct: 394 IALCPVDGQWQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAES-RECYNP 450
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR-CEKIITNGLPSVVDDKECFDLLGPK 437
C QW G+WS CSK C DG R +R C+ + G +E +
Sbjct: 451 ECTANGQWNQW--GHWSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCNEQR 506
Query: 438 -PALYESCNVD 447
PA YE C D
Sbjct: 507 CPAPYEICPED 517
>AL133378-1|CAC34969.2| 1522|Homo sapiens brain-specific
angiogenesis inhibitor 3 protein.
Length = 1522
Score = 58.4 bits (135), Expect = 3e-07
Identities = 62/234 (26%), Positives = 80/234 (34%), Gaps = 25/234 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W C CG G Q R C + E + + L P GV
Sbjct: 298 SQWSTCSVTCGQGSQVRTRTCVSPYGTHCS----GPLRESRVCNN--TALCPVHGVWEEW 351
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA 574
S W+ C TC R+R C Y C T +PC+ P QW
Sbjct: 352 SPWSLCSFTCGRGQRTRTRSCTPPQY---GGRPCEGPETH--HKPCNIALCPV-DGQWQE 405
Query: 575 -TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV C G + R C + S C + +S+ C PE +
Sbjct: 406 WSSWSQCSVTCSNGTQQRSRQC------TAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Query: 634 WYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
W WS C+KSC G R C C + + CNEQ C A
Sbjct: 458 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQC--EGTGEEVRRCNEQRCPA 509
Score = 55.6 bits (128), Expect = 2e-06
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 33/208 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACP-----PQW 389
+S+CS TCG G Q R TC S C L+ ++ C NT CP +W
Sbjct: 300 WSTCSVTCGQGSQVRTRTCVSPYGTH------CSGPLR--ESRVCNNTALCPVHGVWEEW 351
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
P WS CS CG+ G R+R C G P + KP C VD
Sbjct: 352 SP--WSLCSFTCGR-GQRTRTRSCTPPQYGGRPCEGPETH------HKPCNIALCPVDGQ 402
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
W S W C C +G Q R C +G EC R+ E
Sbjct: 403 WQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHG------GSECRGPWAESRECYNPECTA 454
Query: 510 GVDW-MVSEWTGCD-TCLATVRSRVAQC 535
W W+GC +C R+ C
Sbjct: 455 NGQWNQWGHWSGCSKSCDGGWERRIRTC 482
Score = 51.2 bits (117), Expect = 4e-05
Identities = 62/228 (27%), Positives = 85/228 (37%), Gaps = 24/228 (10%)
Query: 417 ITNGLPSVVDDKECFDLLGPKPA--LYES--CNVDAACPTWFI----SPWKPCDKLCGSG 468
+T G S V + C G + L ES CN A CP + SPW C CG G
Sbjct: 305 VTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRG 364
Query: 469 QQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLAT 527
Q+TR C G + + KP + C ++ + +W S W+ C TC
Sbjct: 365 QRTRTRSCTPPQYGGRPCEGPE--THHKPCNIALCPVDG-QWQEW--SSWSQCSVTCSNG 419
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA-TQWSKCSVECGV 586
+ R QC + S C P E C + A QW WS CS C
Sbjct: 420 TQQRSRQCTAAAH---GGSECR-GPWAESRE-CYNPECTA-NGQWNQWGHWSGCSKSCDG 473
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
G + R C GA + +E + + + C P E CP +
Sbjct: 474 GWERRIRTC---QGAVITGQQCEGTGEEVRRCNEQRCPAPYEICPEDY 518
Score = 47.6 bits (108), Expect = 5e-04
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 515 VSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWY 573
V EW+ TC T + +Q T+ + CS P E C+ L W
Sbjct: 294 VEEWSQWSTCSVTC-GQGSQVRTRTCVSPYGTHCS---GPLRESRVCNNTALCPVHGVWE 349
Query: 574 A-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
+ WS CS CG G++TR C + + C E ++ KPC +
Sbjct: 350 EWSPWSLCSFTCGRGQRTRTRSC------TPPQYGGRPCEGPETHH--KPCNIALCPVDG 401
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+W + WS+C+ +C G + RS C S+C + + C C A G+
Sbjct: 402 QWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Score = 44.0 bits (99), Expect = 0.006
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 9/131 (6%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
I P+ Q W ++S CS TC G Q R C + G + + N
Sbjct: 394 IALCPVDGQWQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAES-RECYNP 450
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR-CEKIITNGLPSVVDDKECFDLLGPK 437
C QW G+WS CSK C DG R +R C+ + G +E +
Sbjct: 451 ECTANGQWNQW--GHWSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCNEQR 506
Query: 438 -PALYESCNVD 447
PA YE C D
Sbjct: 507 CPAPYEICPED 517
>BC111720-1|AAI11721.1| 1522|Homo sapiens brain-specific
angiogenesis inhibitor 3 protein.
Length = 1522
Score = 56.4 bits (130), Expect = 1e-06
Identities = 61/234 (26%), Positives = 80/234 (34%), Gaps = 25/234 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W C CG G Q R C + E + + L P GV
Sbjct: 298 SQWSTCSVTCGQGSQVRTRTCVSPYGTHCS----GPLRESRVCNN--TALCPVHGVWEEW 351
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA 574
S W+ C TC R+R C Y C T +PC+ P QW
Sbjct: 352 SPWSLCSFTCGRGQRTRTRSCTPPQY---GGRPCEGPETH--HKPCNIALCPV-DGQWQE 405
Query: 575 -TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV C G + R C + S C + +S+ C PE +
Sbjct: 406 WSSWSQCSVTCSNGTQQRSRQC------TAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Query: 634 WYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
W WS C+KSC G R C C + + C+EQ C A
Sbjct: 458 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQC--EGTGEEVRRCSEQRCPA 509
Score = 55.6 bits (128), Expect = 2e-06
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 33/208 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACP-----PQW 389
+S+CS TCG G Q R TC S C L+ ++ C NT CP +W
Sbjct: 300 WSTCSVTCGQGSQVRTRTCVSPYGTH------CSGPLR--ESRVCNNTALCPVHGVWEEW 351
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
P WS CS CG+ G R+R C G P + KP C VD
Sbjct: 352 SP--WSLCSFTCGR-GQRTRTRSCTPPQYGGRPCEGPETH------HKPCNIALCPVDGQ 402
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
W S W C C +G Q R C +G EC R+ E
Sbjct: 403 WQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHG------GSECRGPWAESRECYNPECTA 454
Query: 510 GVDW-MVSEWTGCD-TCLATVRSRVAQC 535
W W+GC +C R+ C
Sbjct: 455 NGQWNQWGHWSGCSKSCDGGWERRIRTC 482
Score = 50.8 bits (116), Expect = 5e-05
Identities = 62/228 (27%), Positives = 84/228 (36%), Gaps = 24/228 (10%)
Query: 417 ITNGLPSVVDDKECFDLLGPKPA--LYES--CNVDAACPTWFI----SPWKPCDKLCGSG 468
+T G S V + C G + L ES CN A CP + SPW C CG G
Sbjct: 305 VTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRG 364
Query: 469 QQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLAT 527
Q+TR C G + + KP + C ++ + +W S W+ C TC
Sbjct: 365 QRTRTRSCTPPQYGGRPCEGPE--THHKPCNIALCPVDG-QWQEW--SSWSQCSVTCSNG 419
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA-TQWSKCSVECGV 586
+ R QC + S C P E C + A QW WS CS C
Sbjct: 420 TQQRSRQCTAAAH---GGSECR-GPWAESRE-CYNPECTA-NGQWNQWGHWSGCSKSCDG 473
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
G + R C GA + +E + + C P E CP +
Sbjct: 474 GWERRIRTC---QGAVITGQQCEGTGEEVRRCSEQRCPAPYEICPEDY 518
Score = 47.6 bits (108), Expect = 5e-04
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 515 VSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWY 573
V EW+ TC T + +Q T+ + CS P E C+ L W
Sbjct: 294 VEEWSQWSTCSVTC-GQGSQVRTRTCVSPYGTHCS---GPLRESRVCNNTALCPVHGVWE 349
Query: 574 A-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
+ WS CS CG G++TR C + + C E ++ KPC +
Sbjct: 350 EWSPWSLCSFTCGRGQRTRTRSC------TPPQYGGRPCEGPETHH--KPCNIALCPVDG 401
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+W + WS+C+ +C G + RS C S+C + + C C A G+
Sbjct: 402 QWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSEC--RGPWAESRECYNPECTANGQ 457
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 9/131 (6%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
I P+ Q W ++S CS TC G Q R C + G + + N
Sbjct: 394 IALCPVDGQWQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAES-RECYNP 450
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR-CEKIITNGLPSVVDDKECFDLLGPK 437
C QW G+WS CSK C DG R +R C+ + G +E +
Sbjct: 451 ECTANGQWNQW--GHWSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCSEQR 506
Query: 438 -PALYESCNVD 447
PA YE C D
Sbjct: 507 CPAPYEICPED 517
>AB011122-1|BAA25476.2| 1524|Homo sapiens KIAA0550 protein protein.
Length = 1524
Score = 56.4 bits (130), Expect = 1e-06
Identities = 61/234 (26%), Positives = 80/234 (34%), Gaps = 25/234 (10%)
Query: 456 SPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMV 515
S W C CG G Q R C + E + + L P GV
Sbjct: 300 SQWSTCSVTCGQGSQVRTRTCVSPYGTHCS----GPLRESRVCNN--TALCPVHGVWEEW 353
Query: 516 SEWTGCD-TCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA 574
S W+ C TC R+R C Y C T +PC+ P QW
Sbjct: 354 SPWSLCSFTCGRGQRTRTRSCTPPQY---GGRPCEGPETH--HKPCNIALCPV-DGQWQE 407
Query: 575 -TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSK 633
+ WS+CSV C G + R C + S C + +S+ C PE +
Sbjct: 408 WSSWSQCSVTCSNGTQQRSRQC------TAAAHGGSEC--RGPWAESRECYNPECTANGQ 459
Query: 634 WYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEA 686
W WS C+KSC G R C C + + C+EQ C A
Sbjct: 460 WNQWGHWSGCSKSCDGGWERRIRTCQGAVITGQQC--EGTGEEVRRCSEQRCPA 511
Score = 55.6 bits (128), Expect = 2e-06
Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 33/208 (15%)
Query: 336 FSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQTC-NTQACP-----PQW 389
+S+CS TCG G Q R TC S C L+ ++ C NT CP +W
Sbjct: 302 WSTCSVTCGQGSQVRTRTCVSPYGTH------CSGPLR--ESRVCNNTALCPVHGVWEEW 353
Query: 390 VPGNWSRCSKRCGKDGTRSREVRCEKIITNGLPSVVDDKECFDLLGPKPALYESCNVDAA 449
P WS CS CG+ G R+R C G P + KP C VD
Sbjct: 354 SP--WSLCSFTCGR-GQRTRTRSCTPPQYGGRPCEGPETH------HKPCNIALCPVDGQ 404
Query: 450 CPTWFISPWKPCDKLCGSGQQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCE 509
W S W C C +G Q R C +G EC R+ E
Sbjct: 405 WQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHG------GSECRGPWAESRECYNPECTA 456
Query: 510 GVDW-MVSEWTGCD-TCLATVRSRVAQC 535
W W+GC +C R+ C
Sbjct: 457 NGQWNQWGHWSGCSKSCDGGWERRIRTC 484
Score = 50.8 bits (116), Expect = 5e-05
Identities = 62/228 (27%), Positives = 84/228 (36%), Gaps = 24/228 (10%)
Query: 417 ITNGLPSVVDDKECFDLLGPKPA--LYES--CNVDAACPTWFI----SPWKPCDKLCGSG 468
+T G S V + C G + L ES CN A CP + SPW C CG G
Sbjct: 307 VTCGQGSQVRTRTCVSPYGTHCSGPLRESRVCNNTALCPVHGVWEEWSPWSLCSFTCGRG 366
Query: 469 QQTRQVVCYQKNNGRINVLSDDECSEEKPLDRQPCELEPCEGVDWMVSEWTGCD-TCLAT 527
Q+TR C G + + KP + C ++ + +W S W+ C TC
Sbjct: 367 QRTRTRSCTPPQYGGRPCEGPE--THHKPCNIALCPVDG-QWQEW--SSWSQCSVTCSNG 421
Query: 528 VRSRVAQCVTKDYRVVNSSFCSYHPTPALEEPCDKDKLPACQVQWYA-TQWSKCSVECGV 586
+ R QC + S C P E C + A QW WS CS C
Sbjct: 422 TQQRSRQCTAAAH---GGSECR-GPWAESRE-CYNPECTA-NGQWNQWGHWSGCSKSCDG 475
Query: 587 GKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPSKW 634
G + R C GA + +E + + C P E CP +
Sbjct: 476 GWERRIRTC---QGAVITGQQCEGTGEEVRRCSEQRCPAPYEICPEDY 520
Score = 47.6 bits (108), Expect = 5e-04
Identities = 45/178 (25%), Positives = 69/178 (38%), Gaps = 17/178 (9%)
Query: 515 VSEWTGCDTCLATVRSRVAQCVTKDYRVVNSSFCSYHPTPALEEP-CDKDKLPACQVQWY 573
V EW+ TC T + +Q T+ + CS P E C+ L W
Sbjct: 296 VEEWSQWSTCSVTC-GQGSQVRTRTCVSPYGTHCS---GPLRESRVCNNTALCPVHGVWE 351
Query: 574 A-TQWSKCSVECGVGKKTRRVFCGKFDGASVMKVDDSNCPKEEKYNDSKPCEVPEEKCPS 632
+ WS CS CG G++TR C + + C E ++ KPC +
Sbjct: 352 EWSPWSLCSFTCGRGQRTRTRSC------TPPQYGGRPCEGPETHH--KPCNIALCPVDG 403
Query: 633 KWYA-APWSECTKSCGKGLRFRSVVCLRGGKEFSDCPKKSLPDSAGSCNEQSCEALGE 689
+W + WS+C+ +C G + RS C S+C + + C C A G+
Sbjct: 404 QWQEWSSWSQCSVTCSNGTQQRSRQCTAAAHGGSEC--RGPWAESRECYNPECTANGQ 459
Score = 44.4 bits (100), Expect = 0.004
Identities = 38/131 (29%), Positives = 50/131 (38%), Gaps = 9/131 (6%)
Query: 319 IEKAPLPTQRYSWVHGNFSSCSATCGGGIQSRDVTCRSREELEVVDEGLCDDGLKPATNQ 378
I P+ Q W ++S CS TC G Q R C + G + + N
Sbjct: 396 IALCPVDGQWQEW--SSWSQCSVTCSNGTQQRSRQCTAAAHGGSECRGPWAES-RECYNP 452
Query: 379 TCNTQACPPQWVPGNWSRCSKRCGKDGTRSREVR-CEKIITNGLPSVVDDKECFDLLGPK 437
C QW G+WS CSK C DG R +R C+ + G +E +
Sbjct: 453 ECTANGQWNQW--GHWSGCSKSC--DGGWERRIRTCQGAVITGQQCEGTGEEVRRCSEQR 508
Query: 438 -PALYESCNVD 447
PA YE C D
Sbjct: 509 CPAPYEICPED 519
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.137 0.467
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 314,121,784
Number of Sequences: 224733
Number of extensions: 15420680
Number of successful extensions: 34994
Number of sequences better than 10.0: 379
Number of HSP's better than 10.0 without gapping: 245
Number of HSP's successfully gapped in prelim test: 134
Number of HSP's that attempted gapping in prelim test: 27521
Number of HSP's gapped (non-prelim): 4095
length of query: 2102
length of database: 73,234,838
effective HSP length: 101
effective length of query: 2001
effective length of database: 50,536,805
effective search space: 101124146805
effective search space used: 101124146805
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 73 (33.5 bits)
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