Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA005113-TA|BGIBMGA005113-PA|IPR011053|Single hybrid
motif, IPR006255|Dihydrolipoamide succinyltransferase,
IPR000089|Biotin/lipoyl attachment, IPR001078|Catalytic domain of
components of various dehydrogenase complexes
(375 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide succinyl... 306 7e-83
CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein. 306 7e-83
BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide S-succ... 306 7e-83
BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide S-succ... 306 7e-83
AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein. 306 7e-83
D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide succinyl... 304 4e-82
D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial dihydrolipo... 303 6e-82
S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate dehyd... 278 3e-74
Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 ... 115 3e-25
BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide S-acet... 115 3e-25
AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide S-acet... 114 5e-25
Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein. 113 1e-24
U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase co... 113 1e-24
U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl tr... 113 1e-24
AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing compo... 113 1e-24
AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide dehydr... 113 1e-24
J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide acetyltr... 113 1e-24
BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase ... 113 1e-24
X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein. 93 1e-18
J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched ... 93 1e-18
BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branch... 93 1e-18
BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branch... 93 1e-18
M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylas... 92 3e-18
AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branch... 91 6e-18
D17297-1|BAA04130.1| 108|Homo sapiens dihydrolipoamide succinyl... 62 4e-09
X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide S-acetyl... 58 4e-08
>L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 306 bits (752), Expect = 7e-83
Identities = 153/233 (65%), Positives = 176/233 (75%), Gaps = 2/233 (0%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
G R+EH MN+MR+RI++RLKEAQNT AMLTTFNE DMS + R + EAF KK+ +K
Sbjct: 218 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLK 277
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXX--YRDYVDISVAVATPRGLVVPVLRNVES 259
L FMS F+KASA AL +QP YRDY+DISVAVATPRGLVVPV+RNVE+
Sbjct: 278 LGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEA 337
Query: 260 MDYPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMH 319
M++ IE + L EKAR +L DM GGTFTISNGGVFGSL PIIN PQSAILGMH
Sbjct: 338 MNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMH 397
Query: 320 AIFQRPVAINGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
IF RPVAI GKVE+RPMMY+ALTYDHRLIDGREAV FLRK+K+ VEDP +L
Sbjct: 398 GIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLL 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Query: 2 DEVVLEIETDKTALPVMSPGNGKIVKMLVKEGESVKSQQPLF 43
DEVV EIETDKT++ V SP NG I +LV +G V+ PLF
Sbjct: 100 DEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLF 141
>CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein.
Length = 453
Score = 306 bits (752), Expect = 7e-83
Identities = 153/233 (65%), Positives = 176/233 (75%), Gaps = 2/233 (0%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
G R+EH MN+MR+RI++RLKEAQNT AMLTTFNE DMS + R + EAF KK+ +K
Sbjct: 218 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLK 277
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXX--YRDYVDISVAVATPRGLVVPVLRNVES 259
L FMS F+KASA AL +QP YRDY+DISVAVATPRGLVVPV+RNVE+
Sbjct: 278 LGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEA 337
Query: 260 MDYPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMH 319
M++ IE + L EKAR +L DM GGTFTISNGGVFGSL PIIN PQSAILGMH
Sbjct: 338 MNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMH 397
Query: 320 AIFQRPVAINGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
IF RPVAI GKVE+RPMMY+ALTYDHRLIDGREAV FLRK+K+ VEDP +L
Sbjct: 398 GIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLL 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Query: 2 DEVVLEIETDKTALPVMSPGNGKIVKMLVKEGESVKSQQPLF 43
DEVV EIETDKT++ V SP NG I +LV +G V+ PLF
Sbjct: 100 DEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLF 141
>BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 306 bits (752), Expect = 7e-83
Identities = 153/233 (65%), Positives = 176/233 (75%), Gaps = 2/233 (0%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
G R+EH MN+MR+RI++RLKEAQNT AMLTTFNE DMS + R + EAF KK+ +K
Sbjct: 218 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLK 277
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXX--YRDYVDISVAVATPRGLVVPVLRNVES 259
L FMS F+KASA AL +QP YRDY+DISVAVATPRGLVVPV+RNVE+
Sbjct: 278 LGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEA 337
Query: 260 MDYPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMH 319
M++ IE + L EKAR +L DM GGTFTISNGGVFGSL PIIN PQSAILGMH
Sbjct: 338 MNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMH 397
Query: 320 AIFQRPVAINGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
IF RPVAI GKVE+RPMMY+ALTYDHRLIDGREAV FLRK+K+ VEDP +L
Sbjct: 398 GIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLL 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Query: 2 DEVVLEIETDKTALPVMSPGNGKIVKMLVKEGESVKSQQPLF 43
DEVV EIETDKT++ V SP NG I +LV +G V+ PLF
Sbjct: 100 DEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLF 141
>BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 306 bits (752), Expect = 7e-83
Identities = 153/233 (65%), Positives = 176/233 (75%), Gaps = 2/233 (0%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
G R+EH MN+MR+RI++RLKEAQNT AMLTTFNE DMS + R + EAF KK+ +K
Sbjct: 218 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLK 277
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXX--YRDYVDISVAVATPRGLVVPVLRNVES 259
L FMS F+KASA AL +QP YRDY+DISVAVATPRGLVVPV+RNVE+
Sbjct: 278 LGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEA 337
Query: 260 MDYPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMH 319
M++ IE + L EKAR +L DM GGTFTISNGGVFGSL PIIN PQSAILGMH
Sbjct: 338 MNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMH 397
Query: 320 AIFQRPVAINGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
IF RPVAI GKVE+RPMMY+ALTYDHRLIDGREAV FLRK+K+ VEDP +L
Sbjct: 398 GIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLL 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Query: 2 DEVVLEIETDKTALPVMSPGNGKIVKMLVKEGESVKSQQPLF 43
DEVV EIETDKT++ V SP NG I +LV +G V+ PLF
Sbjct: 100 DEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLF 141
>AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein.
Length = 453
Score = 306 bits (752), Expect = 7e-83
Identities = 153/233 (65%), Positives = 176/233 (75%), Gaps = 2/233 (0%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
G R+EH MN+MR+RI++RLKEAQNT AMLTTFNE DMS + R + EAF KK+ +K
Sbjct: 218 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLK 277
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXX--YRDYVDISVAVATPRGLVVPVLRNVES 259
L FMS F+KASA AL +QP YRDY+DISVAVATPRGLVVPV+RNVE+
Sbjct: 278 LGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEA 337
Query: 260 MDYPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMH 319
M++ IE + L EKAR +L DM GGTFTISNGGVFGSL PIIN PQSAILGMH
Sbjct: 338 MNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMH 397
Query: 320 AIFQRPVAINGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
IF RPVAI GKVE+RPMMY+ALTYDHRLIDGREAV FLRK+K+ VEDP +L
Sbjct: 398 GIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLL 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Query: 2 DEVVLEIETDKTALPVMSPGNGKIVKMLVKEGESVKSQQPLF 43
DEVV EIETDKT++ V SP NG I +LV +G V+ PLF
Sbjct: 100 DEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLF 141
>D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 304 bits (746), Expect = 4e-82
Identities = 152/233 (65%), Positives = 175/233 (75%), Gaps = 2/233 (0%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
G R+EH MN+MR+RI++RLKEAQNT AMLTTFNE DMS + R + EAF KK+ +K
Sbjct: 218 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLK 277
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXX--YRDYVDISVAVATPRGLVVPVLRNVES 259
L FMS F+KASA AL +QP Y DY+DISVAVATPRGLVVPV+RNVE+
Sbjct: 278 LGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYTDYIDISVAVATPRGLVVPVIRNVEA 337
Query: 260 MDYPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMH 319
M++ IE + L EKAR +L DM GGTFTISNGGVFGSL PIIN PQSAILGMH
Sbjct: 338 MNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTPIINPPQSAILGMH 397
Query: 320 AIFQRPVAINGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
IF RPVAI GKVE+RPMMY+ALTYDHRLIDGREAV FLRK+K+ VEDP +L
Sbjct: 398 GIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLL 450
Score = 49.2 bits (112), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Query: 2 DEVVLEIETDKTALPVMSPGNGKIVKMLVKEGESVKSQQPLF 43
DEVV EIETDKT++ V SP NG I +LV +G V+ PLF
Sbjct: 100 DEVVCEIETDKTSVQVPSPANGVIEALLVPDGGKVEGGTPLF 141
>D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial
dihydrolipoamide succinyltransferase protein.
Length = 453
Score = 303 bits (744), Expect = 6e-82
Identities = 152/233 (65%), Positives = 175/233 (75%), Gaps = 2/233 (0%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
G R+EH MN+MR+RI++RLKEAQNT AMLTTFNE DMS + R + EAF KK+ +K
Sbjct: 218 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEMRARHKEAFLKKHNLK 277
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXX--YRDYVDISVAVATPRGLVVPVLRNVES 259
L FMS F+KASA AL +QP YRDY+DISVAVATPRGLVVPV+RNVE+
Sbjct: 278 LGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVATPRGLVVPVIRNVEA 337
Query: 260 MDYPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMH 319
M++ IE + L EKAR +L DM GGTFTISNGGVFGSL IIN PQSAILGMH
Sbjct: 338 MNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFGTTIINPPQSAILGMH 397
Query: 320 AIFQRPVAINGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
IF RPVAI GKVE+RPMMY+ALTYDHRLIDGREAV FLRK+K+ VEDP +L
Sbjct: 398 GIFDRPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLL 450
Score = 49.6 bits (113), Expect = 2e-05
Identities = 24/42 (57%), Positives = 29/42 (69%)
Query: 2 DEVVLEIETDKTALPVMSPGNGKIVKMLVKEGESVKSQQPLF 43
DEVV EIETDKT++ V SP NG I +LV +G V+ PLF
Sbjct: 100 DEVVCEIETDKTSVQVPSPANGVIEALLVPDGTKVEGGTPLF 141
>S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate
dehydrogenase complex dihydrolipoyl succinyltransferase
protein.
Length = 451
Score = 278 bits (681), Expect = 3e-74
Identities = 141/233 (60%), Positives = 168/233 (72%), Gaps = 3/233 (1%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
G +EH MN+MR+ I++RLKEAQNT MLT FNE D+S + R + EAF KK+ +K
Sbjct: 217 GLHSEHREKMNRMRQCIAQRLKEAQNTVPMLTIFNEIDVSNIQKMRARHKEAFLKKHNLK 276
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXX--YRDYVDISVAVATPRGLVVPVLRNVES 259
L FMS +KASA AL +QP YRDY+DISVAVATP+GLVVPV+RNVE+
Sbjct: 277 LGFMSASVKASAFALQEQPVVNAVIDDITKEVVYRDYIDISVAVATPQGLVVPVIRNVEA 336
Query: 260 MDYPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMH 319
M+Y IE + L EKAR + DM GGTFTISNGGVFGSL P+ + P SAILGMH
Sbjct: 337 MNYADIEQTITELGEKARKNEFAIEDMDGGTFTISNGGVFGSLFEHPL-STPLSAILGMH 395
Query: 320 AIFQRPVAINGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
IF +PVAI GKVE+RPMMY+ALTYDHRLIDGREAV FLRK+K+ VEDP +L
Sbjct: 396 GIFDKPVAIGGKVEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLL 448
Score = 47.2 bits (107), Expect = 9e-05
Identities = 23/42 (54%), Positives = 27/42 (64%)
Query: 2 DEVVLEIETDKTALPVMSPGNGKIVKMLVKEGESVKSQQPLF 43
DEVV EIETDKT + V SP NG I + V +G V+ PLF
Sbjct: 99 DEVVCEIETDKTLVQVPSPANGMIEALFVPDGGKVEGGTPLF 140
>Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 to
561) protein.
Length = 615
Score = 115 bits (276), Expect = 3e-25
Identities = 75/226 (33%), Positives = 119/226 (52%), Gaps = 4/226 (1%)
Query: 149 VPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVKLSFMSPF 208
+P++ +R+ I++RL +++ T + +M +++ RK + + K+S
Sbjct: 391 IPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS--KISVNDFI 448
Query: 209 LKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMDYPRIELA 268
+KASA A + P VD+SVAV+TP GL+ P++ N I
Sbjct: 449 IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND 508
Query: 269 MGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAIFQRPV-A 327
+ +LA KAR GKL P + QGGTFTISN G+FG IIN PQ+ IL + A + V A
Sbjct: 509 VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA 568
Query: 328 INGK-VEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
N K ++ MM + L+ DHR++DG +L + + +E P ++L
Sbjct: 569 DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITML 614
>BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 115 bits (276), Expect = 3e-25
Identities = 75/226 (33%), Positives = 119/226 (52%), Gaps = 4/226 (1%)
Query: 149 VPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVKLSFMSPF 208
+P++ +R+ I++RL +++ T + +M +++ RK + + K+S
Sbjct: 423 IPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS--KISVNDFI 480
Query: 209 LKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMDYPRIELA 268
+KASA A + P VD+SVAV+TP GL+ P++ N I
Sbjct: 481 IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND 540
Query: 269 MGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAIFQRPV-A 327
+ +LA KAR GKL P + QGGTFTISN G+FG IIN PQ+ IL + A + V A
Sbjct: 541 VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA 600
Query: 328 INGK-VEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
N K ++ MM + L+ DHR++DG +L + + +E P ++L
Sbjct: 601 DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITML 646
>AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 114 bits (274), Expect = 5e-25
Identities = 75/226 (33%), Positives = 118/226 (52%), Gaps = 4/226 (1%)
Query: 149 VPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVKLSFMSPF 208
+P++ +R+ I++RL +++ T +M +++ RK + + K+S
Sbjct: 423 IPISNIRRVIAQRLMQSKQTIPHYYLSINVNMGEVLLVRKELNKILEGRS--KISVNDFI 480
Query: 209 LKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMDYPRIELA 268
+KASA A + P VD+SVAV+TP GL+ P++ N I
Sbjct: 481 IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND 540
Query: 269 MGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAIFQRPV-A 327
+ +LA KAR GKL P + QGGTFTISN G+FG IIN PQ+ IL + A + V A
Sbjct: 541 VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA 600
Query: 328 INGK-VEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
N K ++ MM + L+ DHR++DG +L + + +E P ++L
Sbjct: 601 DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITML 646
>Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein.
Length = 501
Score = 113 bits (272), Expect = 1e-24
Identities = 74/234 (31%), Positives = 126/234 (53%), Gaps = 16/234 (6%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
GT TE +P + +R+ I++RL E+++T +CD+ ++ R+ + K +K
Sbjct: 273 GTFTE--IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLV-----KDDIK 325
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMD 261
+S +KA+A L P ++DISVAVAT +GL+ P++++ +
Sbjct: 326 VSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKG 385
Query: 262 YPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAI 321
I ++ AL++KAR GKL P + QGG+F+ISN G+FG +IN PQ+ IL +
Sbjct: 386 IQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRF 445
Query: 322 FQRPVAI-------NGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDP 368
RPV N K++ R ++ + ++ D R++D A FL+ K+ +E+P
Sbjct: 446 --RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase
complex protein X subunit precursor protein.
Length = 501
Score = 113 bits (272), Expect = 1e-24
Identities = 74/234 (31%), Positives = 126/234 (53%), Gaps = 16/234 (6%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
GT TE +P + +R+ I++RL E+++T +CD+ ++ R+ + K +K
Sbjct: 273 GTFTE--IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLV-----KDDIK 325
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMD 261
+S +KA+A L P ++DISVAVAT +GL+ P++++ +
Sbjct: 326 VSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKG 385
Query: 262 YPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAI 321
I ++ AL++KAR GKL P + QGG+F+ISN G+FG +IN PQ+ IL +
Sbjct: 386 IQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRF 445
Query: 322 FQRPVAI-------NGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDP 368
RPV N K++ R ++ + ++ D R++D A FL+ K+ +E+P
Sbjct: 446 --RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl
transferase protein.
Length = 375
Score = 113 bits (272), Expect = 1e-24
Identities = 74/234 (31%), Positives = 126/234 (53%), Gaps = 16/234 (6%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
GT TE +P + +R+ I++RL E+++T +CD+ ++ R+ + K +K
Sbjct: 147 GTFTE--IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLV-----KDDIK 199
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMD 261
+S +KA+A L P ++DISVAVAT +GL+ P++++ +
Sbjct: 200 VSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKG 259
Query: 262 YPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAI 321
I ++ AL++KAR GKL P + QGG+F+ISN G+FG +IN PQ+ IL +
Sbjct: 260 IQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRF 319
Query: 322 FQRPVAI-------NGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDP 368
RPV N K++ R ++ + ++ D R++D A FL+ K+ +E+P
Sbjct: 320 --RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 371
>AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing
component X protein.
Length = 501
Score = 113 bits (272), Expect = 1e-24
Identities = 74/234 (31%), Positives = 126/234 (53%), Gaps = 16/234 (6%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
GT TE +P + +R+ I++RL E+++T +CD+ ++ R+ + K +K
Sbjct: 273 GTFTE--IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLV-----KDDIK 325
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMD 261
+S +KA+A L P ++DISVAVAT +GL+ P++++ +
Sbjct: 326 VSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKG 385
Query: 262 YPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAI 321
I ++ AL++KAR GKL P + QGG+F+ISN G+FG +IN PQ+ IL +
Sbjct: 386 IQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRF 445
Query: 322 FQRPVAI-------NGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDP 368
RPV N K++ R ++ + ++ D R++D A FL+ K+ +E+P
Sbjct: 446 --RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide
dehydrogenase-binding protein protein.
Length = 501
Score = 113 bits (272), Expect = 1e-24
Identities = 74/234 (31%), Positives = 126/234 (53%), Gaps = 16/234 (6%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
GT TE +P + +R+ I++RL E+++T +CD+ ++ R+ + K +K
Sbjct: 273 GTFTE--IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLV-----KDDIK 325
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMD 261
+S +KA+A L P ++DISVAVAT +GL+ P++++ +
Sbjct: 326 VSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKG 385
Query: 262 YPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAI 321
I ++ AL++KAR GKL P + QGG+F+ISN G+FG +IN PQ+ IL +
Sbjct: 386 IQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRF 445
Query: 322 FQRPVAI-------NGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDP 368
RPV N K++ R ++ + ++ D R++D A FL+ K+ +E+P
Sbjct: 446 --RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide
acetyltransferase protein.
Length = 613
Score = 113 bits (271), Expect = 1e-24
Identities = 75/226 (33%), Positives = 118/226 (52%), Gaps = 5/226 (2%)
Query: 149 VPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVKLSFMSPF 208
+P++ +R+ I++RL +++ T + C +++ RK + + K+S
Sbjct: 390 IPISNIRRVIAQRLMQSKQTIPHYYLLS-CKYGEVLLVRKELNKILEGRS--KISVNDFI 446
Query: 209 LKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMDYPRIELA 268
+KASA A + P VD+SVAV+TP GL+ P++ N I
Sbjct: 447 IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND 506
Query: 269 MGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAIFQRPV-A 327
+ +LA KAR GKL P + QGGTFTISN G+FG IIN PQ+ IL + A + V A
Sbjct: 507 VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA 566
Query: 328 INGK-VEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDPTSIL 372
N K ++ MM + L+ DHR++DG +L + + +E P ++L
Sbjct: 567 DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITML 612
>BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase
complex, component X protein.
Length = 501
Score = 113 bits (271), Expect = 1e-24
Identities = 74/234 (31%), Positives = 126/234 (53%), Gaps = 16/234 (6%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVK 201
GT TE +P + +R+ I++RL E+++T +CD+ ++ R+ + K +K
Sbjct: 273 GTFTE--IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLV-----KDDIK 325
Query: 202 LSFMSPFLKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMD 261
+S +KA+A L P ++DISVAVAT +GL+ P++++ +
Sbjct: 326 VSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATVKGLLTPIIKDAAAKG 385
Query: 262 YPRIELAMGALAEKARTGKLTPADMQGGTFTISNGGVFGSLLSMPIINLPQSAILGMHAI 321
I ++ AL++KAR GKL P + QGG+F+ISN G+FG +IN PQ+ IL +
Sbjct: 386 IQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRF 445
Query: 322 FQRPVAI-------NGKVEIRPMMYLALTYDHRLIDGREAVLFLRKVKSGVEDP 368
RPV N K++ R ++ + ++ D R++D A FL+ K+ +E+P
Sbjct: 446 --RPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein.
Length = 482
Score = 93.5 bits (222), Expect = 1e-18
Identities = 63/200 (31%), Positives = 103/200 (51%), Gaps = 4/200 (2%)
Query: 176 NECDMSKLMAFRKANLEAFTKKYGVKLSFMSPFLKASANALMDQPXXXXXXXXX--XXXY 233
+E D+++L+ R+ L+ G+KLSFM FLKA++ L+ P Y
Sbjct: 280 DEIDLTELVKLRE-ELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITY 338
Query: 234 RDYVDISVAVATPRGLVVPVLRNVESMDYPRIELAMGALAEKARTGKLTPADMQGGTFTI 293
+ +I +A+ T +GL+VP ++NV+ I + L + G+L+ D+ GGTFT+
Sbjct: 339 KASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTL 398
Query: 294 SNGGVFGSLLSMPIINLPQSAILGMHAIFQRP-VAINGKVEIRPMMYLALTYDHRLIDGR 352
SN G G + P+I P+ AI + +I P G+V +M ++ + DHR+IDG
Sbjct: 399 SNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
Query: 353 EAVLFLRKVKSGVEDPTSIL 372
F KS +E+P +L
Sbjct: 459 TMSRFSNLWKSYLENPAFML 478
>J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched
chain acyltransferase mRNA, complete cds. ).
Length = 477
Score = 93.5 bits (222), Expect = 1e-18
Identities = 63/200 (31%), Positives = 103/200 (51%), Gaps = 4/200 (2%)
Query: 176 NECDMSKLMAFRKANLEAFTKKYGVKLSFMSPFLKASANALMDQPXXXXXXXXX--XXXY 233
+E D+++L+ R+ L+ G+KLSFM FLKA++ L+ P Y
Sbjct: 275 DEIDLTELVKLRE-ELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITY 333
Query: 234 RDYVDISVAVATPRGLVVPVLRNVESMDYPRIELAMGALAEKARTGKLTPADMQGGTFTI 293
+ +I +A+ T +GL+VP ++NV+ I + L + G+L+ D+ GGTFT+
Sbjct: 334 KASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTL 393
Query: 294 SNGGVFGSLLSMPIINLPQSAILGMHAIFQRP-VAINGKVEIRPMMYLALTYDHRLIDGR 352
SN G G + P+I P+ AI + +I P G+V +M ++ + DHR+IDG
Sbjct: 394 SNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 453
Query: 353 EAVLFLRKVKSGVEDPTSIL 372
F KS +E+P +L
Sbjct: 454 TMSRFSNLWKSYLENPAFML 473
>BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase (E2 component of branched chain ke
protein.
Length = 482
Score = 93.5 bits (222), Expect = 1e-18
Identities = 63/200 (31%), Positives = 103/200 (51%), Gaps = 4/200 (2%)
Query: 176 NECDMSKLMAFRKANLEAFTKKYGVKLSFMSPFLKASANALMDQPXXXXXXXXX--XXXY 233
+E D+++L+ R+ L+ G+KLSFM FLKA++ L+ P Y
Sbjct: 280 DEIDLTELVKLRE-ELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITY 338
Query: 234 RDYVDISVAVATPRGLVVPVLRNVESMDYPRIELAMGALAEKARTGKLTPADMQGGTFTI 293
+ +I +A+ T +GL+VP ++NV+ I + L + G+L+ D+ GGTFT+
Sbjct: 339 KASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTL 398
Query: 294 SNGGVFGSLLSMPIINLPQSAILGMHAIFQRP-VAINGKVEIRPMMYLALTYDHRLIDGR 352
SN G G + P+I P+ AI + +I P G+V +M ++ + DHR+IDG
Sbjct: 399 SNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
Query: 353 EAVLFLRKVKSGVEDPTSIL 372
F KS +E+P +L
Sbjct: 459 TMSRFSNLWKSYLENPAFML 478
>BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 93.5 bits (222), Expect = 1e-18
Identities = 63/200 (31%), Positives = 103/200 (51%), Gaps = 4/200 (2%)
Query: 176 NECDMSKLMAFRKANLEAFTKKYGVKLSFMSPFLKASANALMDQPXXXXXXXXX--XXXY 233
+E D+++L+ R+ L+ G+KLSFM FLKA++ L+ P Y
Sbjct: 280 DEIDLTELVKLRE-ELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITY 338
Query: 234 RDYVDISVAVATPRGLVVPVLRNVESMDYPRIELAMGALAEKARTGKLTPADMQGGTFTI 293
+ +I +A+ T +GL+VP ++NV+ I + L + G+L+ D+ GGTFT+
Sbjct: 339 KASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTL 398
Query: 294 SNGGVFGSLLSMPIINLPQSAILGMHAIFQRP-VAINGKVEIRPMMYLALTYDHRLIDGR 352
SN G G + P+I P+ AI + +I P G+V +M ++ + DHR+IDG
Sbjct: 399 SNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
Query: 353 EAVLFLRKVKSGVEDPTSIL 372
F KS +E+P +L
Sbjct: 459 TMSRFSNLWKSYLENPAFML 478
>M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylase
protein.
Length = 477
Score = 91.9 bits (218), Expect = 3e-18
Identities = 62/200 (31%), Positives = 103/200 (51%), Gaps = 4/200 (2%)
Query: 176 NECDMSKLMAFRKANLEAFTKKYGVKLSFMSPFLKASANALMDQPXXXXXXXXX--XXXY 233
+E D+++L+ R+ L+ G+KLSFM FLKA++ L+ P Y
Sbjct: 275 DEIDLTELVKLRE-ELKPIAFARGIKLSFMPFFLKAASLGLLPFPILNASVDENCQNITY 333
Query: 234 RDYVDISVAVATPRGLVVPVLRNVESMDYPRIELAMGALAEKARTGKLTPADMQGGTFTI 293
+ +I +A+ T +G++VP ++NV+ I + L + G+L+ D+ GGTFT+
Sbjct: 334 KASHNIGIAMDTEQGVIVPNVKNVQICSIFDIATELNRLQKLGSVGQLSTTDLTGGTFTL 393
Query: 294 SNGGVFGSLLSMPIINLPQSAILGMHAIFQRP-VAINGKVEIRPMMYLALTYDHRLIDGR 352
SN G G + P+I P+ AI + +I P G+V +M ++ + DHR+IDG
Sbjct: 394 SNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 453
Query: 353 EAVLFLRKVKSGVEDPTSIL 372
F KS +E+P +L
Sbjct: 454 TMSRFSNLWKSYLENPAFML 473
>AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 91.1 bits (216), Expect = 6e-18
Identities = 62/200 (31%), Positives = 102/200 (51%), Gaps = 4/200 (2%)
Query: 176 NECDMSKLMAFRKANLEAFTKKYGVKLSFMSPFLKASANALMDQPXXXXXXXXX--XXXY 233
+E D+++L+ R+ L+ G+KLSFM FLKA++ L+ P Y
Sbjct: 280 DEIDLTELVKLRE-ELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITY 338
Query: 234 RDYVDISVAVATPRGLVVPVLRNVESMDYPRIELAMGALAEKARTGKLTPADMQGGTFTI 293
+ +I +A+ T +GL+VP ++NV+ I + L + +L+ D+ GGTFT+
Sbjct: 339 KASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTL 398
Query: 294 SNGGVFGSLLSMPIINLPQSAILGMHAIFQRP-VAINGKVEIRPMMYLALTYDHRLIDGR 352
SN G G + P+I P+ AI + +I P G+V +M ++ + DHR+IDG
Sbjct: 399 SNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVIDGA 458
Query: 353 EAVLFLRKVKSGVEDPTSIL 372
F KS +E+P +L
Sbjct: 459 TMSRFSNLWKSYLENPAFML 478
>D17297-1|BAA04130.1| 108|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 108
Score = 61.7 bits (143), Expect = 4e-09
Identities = 28/39 (71%), Positives = 33/39 (84%)
Query: 142 GTRTEHPVPMNKMRKRISERLKEAQNTTAMLTTFNECDM 180
G R+EH MN+MR+RI++RLKEAQNT AMLTTFNE DM
Sbjct: 70 GLRSEHREKMNRMRQRIAQRLKEAQNTCAMLTTFNEIDM 108
>X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide
S-acetyltransferase protein.
Length = 220
Score = 58.4 bits (135), Expect = 4e-08
Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 2/135 (1%)
Query: 149 VPMNKMRKRISERLKEAQNTTAMLTTFNECDMSKLMAFRKANLEAFTKKYGVKLSFMSPF 208
+P++ +R+ I++RL +++ T + +M +++ RK + + K+S
Sbjct: 87 IPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS--KISVNDFI 144
Query: 209 LKASANALMDQPXXXXXXXXXXXXYRDYVDISVAVATPRGLVVPVLRNVESMDYPRIELA 268
+K SA A + P VD+SVAV+TP GL+ P++ N I
Sbjct: 145 IKRSALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND 204
Query: 269 MGALAEKARTGKLTP 283
+ +LA KAR GKL P
Sbjct: 205 VVSLATKAREGKLQP 219
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.376
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 38,371,487
Number of Sequences: 224733
Number of extensions: 1307877
Number of successful extensions: 2436
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 2348
Number of HSP's gapped (non-prelim): 52
length of query: 375
length of database: 73,234,838
effective HSP length: 91
effective length of query: 284
effective length of database: 52,784,135
effective search space: 14990694340
effective search space used: 14990694340
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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