Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA004579-TA|BGIBMGA004579-PA|IPR000008|C2
calcium-dependent membrane targeting, IPR001849|Pleckstrin-like,
IPR010439|Protein of unknown function DUF1041, IPR008973|C2
calcium/lipid-binding region, CaLB
(1115 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF458662-1|AAM61861.1| 1274|Homo sapiens calcium-dependent activ... 1193 0.0
AB046811-1|BAB13417.1| 1018|Homo sapiens KIAA1591 protein protein. 1158 0.0
AF401638-1|AAN38707.1| 1254|Homo sapiens CADPS2 protein. 1157 0.0
AK025672-1|BAB15210.1| 879|Homo sapiens protein ( Homo sapiens ... 1026 0.0
AB032947-1|BAA86435.2| 1390|Homo sapiens KIAA1121 protein protein. 960 0.0
AY264289-1|AAP22132.1| 1296|Homo sapiens Ca2+-dependent activato... 914 0.0
BC131731-1|AAI31732.1| 776|Homo sapiens CADPS protein protein. 889 0.0
AK000768-1|BAA91372.1| 431|Homo sapiens protein ( Homo sapiens ... 428 e-119
AK098170-1|BAC05249.1| 550|Homo sapiens protein ( Homo sapiens ... 353 3e-96
BC072684-1|AAH72684.1| 233|Homo sapiens CADPS protein protein. 169 4e-41
BC015754-1|AAH15754.1| 222|Homo sapiens CADPS protein protein. 151 1e-35
BC029460-1|AAH29460.1| 138|Homo sapiens CADPS protein protein. 145 7e-34
U36448-1|AAA79701.1| 223|Homo sapiens Ca2+-dependent activator ... 123 4e-27
AK127506-1|BAC87012.1| 151|Homo sapiens protein ( Homo sapiens ... 103 5e-21
BC111800-1|AAI11801.1| 1197|Homo sapiens UNC13B protein protein. 48 2e-04
BC111781-1|AAI11782.1| 1610|Homo sapiens UNC13B protein protein. 48 2e-04
AL354669-2|CAH71208.1| 1591|Homo sapiens unc-13 homolog B (C. el... 48 2e-04
AL354669-1|CAH71207.1| 1622|Homo sapiens unc-13 homolog B (C. el... 48 2e-04
AL353795-12|CAH71004.1| 1591|Homo sapiens unc-13 homolog B (C. e... 48 2e-04
AL353795-11|CAH71003.1| 1622|Homo sapiens unc-13 homolog B (C. e... 48 2e-04
AL160274-2|CAH73361.1| 1591|Homo sapiens unc-13 homolog B (C. el... 48 2e-04
AL160274-1|CAH73362.1| 1622|Homo sapiens unc-13 homolog B (C. el... 48 2e-04
AF020202-1|AAC19406.1| 1591|Homo sapiens Munc13 protein. 48 2e-04
AB209998-1|BAE06080.1| 1620|Homo sapiens UNC13B variant protein ... 48 2e-04
AK091491-1|BAC03675.1| 891|Homo sapiens protein ( Homo sapiens ... 45 0.002
AB028955-1|BAA82984.2| 1702|Homo sapiens KIAA1032 protein protein. 44 0.003
U10886-1|AAB36687.1| 1337|Homo sapiens density enhanced phosphat... 35 1.4
D37781-1|BAA07035.1| 1337|Homo sapiens protein-tyrosine phosphat... 35 1.4
AF387844-1|AAM69432.1| 1305|Homo sapiens protein tyrosine phosph... 35 1.4
AY028805-1|AAK37776.1| 532|Homo sapiens leukocyte-derived argin... 32 10.0
AK074072-1|BAB84898.1| 373|Homo sapiens FLJ00143 protein protein. 32 10.0
AB163917-1|BAD90015.1| 532|Homo sapiens leukocyte-derived argin... 32 10.0
AB109031-1|BAC78818.1| 960|Homo sapiens leukocyte-derived argin... 32 10.0
>AF458662-1|AAM61861.1| 1274|Homo sapiens calcium-dependent activator
protein for secretion protein protein.
Length = 1274
Score = 1193 bits (2954), Expect = 0.0
Identities = 613/1067 (57%), Positives = 766/1067 (71%), Gaps = 115/1067 (10%)
Query: 1 MFQQILGVKKFEHQLLFNALLLDSADEQAAAIRRELDGRMQKVNEMEKNRKLMPKFVLKE 60
MFQ ILG+KKFEHQLL+NA LD+ DEQAA IRRELDGR+Q +++ + RK PKFV KE
Sbjct: 276 MFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQMADQIARERKF-PKFVSKE 334
Query: 61 MESLYIEELKSSINLLMANLESLPVSKGGADSKYGLHKIKRYNHRSNAGPDPSPRLSKQL 120
ME++YIEELKSS+NLLMANLES+PVSKGG ++ L K+KR +H +
Sbjct: 335 MENMYIEELKSSVNLLMANLESMPVSKGG---EFKLQKLKR-SHNA-------------- 376
Query: 121 CFRSQGSLANKLTGETDGEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLAPNRIVYCTMEV 180
S+ + GE E + QL+K DVVL+F +EVV+MEV+GLKSLAPNRIVYCTMEV
Sbjct: 377 ------SIIDM--GE---ESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVYCTMEV 425
Query: 181 EGGDKLQTDQAEASKPMWDTQGDFSTTQPLPAVKVKLYTENPGVLALEDKELGKVVLRPT 240
EGG+KLQTDQAEASKP W TQGDFSTT LPAVKVKL+TE+ GVLALEDKELG+V+L PT
Sbjct: 426 EGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPT 485
Query: 241 PLSSKAPEWHRMTVPKNLPDQDLRIKIACRMDKPLNMKHCGYLHVIGKNVWRKWKRRYMV 300
P S K EWH+MTV KN PDQDL+IK+A RMDKP NMKH GYL IGKNVW++WK+R+ V
Sbjct: 486 PNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWKKRFFV 545
Query: 301 LVQVSQYTFALCSYKDKKSEPAEMMQLDGFTVDYIELASAQLIVGQGKKENFNTKLEGAK 360
LVQVSQYTFA+CSY++KK+EP E++QLDG+TVDY + LEG +
Sbjct: 546 LVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPG---------------LEGGR 590
Query: 361 YFMNAVRDGESVLMGTTDENECHLWVMALYRATGQSHKPTPPTTSDTHHKIMGD------ 414
F NAV++G++V+ + DE + LWV A+YRATGQSHKP PPT + G+
Sbjct: 591 AFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDA 650
Query: 415 ------ADKARKHGMEDYIQADPCQFDHHQLFCTLQSLTLKYRLQDPYCSLGWFSPGQVF 468
AD+A+KHGM+++I ++PC FDH LF +GWFSPGQVF
Sbjct: 651 PISQFYADRAQKHGMDEFISSNPCNFDHASLF-----------------EMGWFSPGQVF 693
Query: 469 VLDEYCARYGVRGCYRHLCYLSDLLDVAESGQQTVDPTLMHYSFAFCASHVHGNRVSPTG 528
VLDEYCAR GVRGC+RHLCYL DLL+ AE+G +DPTL+HYSFAFCASHVHGNR
Sbjct: 694 VLDEYCARNGVRGCHRHLCYLRDLLERAENGAM-IDPTLLHYSFAFCASHVHGNR----- 747
Query: 529 DVVHSTATLPGRPDGVGSITVQEKEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGALKA 588
PDG+G++TV+EKE+F EIKERL+ LL++QIT+FRY FPFGRPEGALKA
Sbjct: 748 ------------PDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKA 795
Query: 589 TLSLLERVLMKDVVTPVAPEEVRTMIQTSLENAALLNYTQLSQKANIEEDLRGDTMVTPA 648
TLSLLERVLMKD+VTPV EEV+T+I+ LE AAL+NY++LS+ A IEE++ ++TPA
Sbjct: 796 TLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEENV--GRLITPA 853
Query: 649 KKLEDLIHLAELCVDLLQHNEEHYAEAFAWFSELLVEHAEIFWALFAVDMDRVLSEQPPD 708
KKLED I LAEL +++LQ NEEH+AEAFAW+S+L+VEHAE F +LFAVDMD L QPPD
Sbjct: 854 KKLEDTIRLAELVIEVLQQNEEHHAEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPD 913
Query: 709 TWDSFPLFQILNDYLRTDTDTEGTYPMDNLKGGRFHEHLRDTFAPLVVRYVDLMESSIAQ 768
TWDSFPLFQ+LND+LRTD NL G+FH+HL+D FAPLVVRYVDLMESSIAQ
Sbjct: 914 TWDSFPLFQLLNDFLRTDY---------NLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQ 964
Query: 769 SLHKGFEKERWEIKGNGCATSEELFWKLDALQCFIRDLHWPEPEFRSHLEQRLKLMASDM 828
S+H+GFE+E WE NG TSE+LFWKLDALQ FIRDLHWPE EF HLEQRLKLMASDM
Sbjct: 965 SIHRGFERESWEPVNNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDM 1024
Query: 829 METLIQRTEAAFQSWLKKSVTFMSTDYILPAETCAMVNVALDAKNQALKLCAVEGVDIYQ 888
+E+ ++RT AF+ L+K T STD+ +P C M NV +DAK Q+ KLC++E +Q
Sbjct: 1025 IESCVKRTRIAFEVKLQK--TSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQ 1082
Query: 889 YHAKMDGQIEACLVAMATGMTTRLSAVLEATLAKIARFDEGSLIGSILTI--------AN 940
YH+K+D IE + M T + + +LE LAK++R+DEG+L S L+ +
Sbjct: 1083 YHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVD 1142
Query: 941 VSGSGKDIGQGYVNFMRNSMDQIRSKVTDELWILQLFEQWYGNQVTMINNWLSERP--AL 998
V G D+ YV F+R+S D +R KV E++I +LF+QWY + + +I WL++R L
Sbjct: 1143 VPKPGMDVADAYVTFVRHSQDVLRDKVNGEMYIERLFDQWYNSSMNVICTWLTDRMDLQL 1202
Query: 999 HPHQVACLSILLKKMYSDFELQGVIDDKLNSKTYQGVAARMHTEEAT 1045
H +Q+ L ++KK Y DF LQGV+D NSKTY+ + R+ EEAT
Sbjct: 1203 HIYQLKTLIRMVKKTYRDFRLQGVLDSTFNSKTYETIRNRLTVEEAT 1249
>AB046811-1|BAB13417.1| 1018|Homo sapiens KIAA1591 protein protein.
Length = 1018
Score = 1158 bits (2869), Expect = 0.0
Identities = 587/1068 (54%), Positives = 761/1068 (71%), Gaps = 100/1068 (9%)
Query: 1 MFQQILGVKKFEHQLLFNALLLDSADEQAAAIRRELDGRMQKVNEMEKNRKLMPKFVLKE 60
MFQQILG+KK EHQLL+NA LD+ADEQAA IRRELDGR+Q ++M K RK PKF+ K+
Sbjct: 5 MFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKF-PKFIAKD 63
Query: 61 MESLYIEELKSSINLLMANLESLPVSKGGADSKYGLHKIKRYNHRSNAGPDPSPRLSKQL 120
ME++YIEEL+SS+NLLMANLESLPVSKGG + K L K+KR S+
Sbjct: 64 MENMYIEELRSSVNLLMANLESLPVSKGGPEFK--LQKLKR---------------SQNS 106
Query: 121 CFRSQGSLANKLTGETDGEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLAPNRIVYCTMEV 180
F G E + QL+K DVVL+F +E+V+MEV+GLKS+APNRIVYCTMEV
Sbjct: 107 AFLDIGD-----------ENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEV 155
Query: 181 EGGDKLQTDQAEASKPMWDTQGDFSTTQPLPAVKVKLYTENPGVLALEDKELGKVVLRPT 240
EG +KLQTDQAEAS+P W TQGDF+TT P P VKVKL+TE+ GVLALEDKELG+V+L PT
Sbjct: 156 EG-EKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPT 214
Query: 241 PLSSKAPEWHRMTVPKNLPDQDLRIKIACRMDKPLNMKHCGYLHVIGKNVWRKWKRRYMV 300
SSK+ E HRM VPKN D DL+IK+A RMDKP +MKH GYL+ +G+ VW++WK+RY V
Sbjct: 215 SNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFV 274
Query: 301 LVQVSQYTFALCSYKDKKSEPAEMMQLDGFTVDYIELASAQLIVGQGKKENFNTKLEGAK 360
LVQVSQYTFA+CSY++KKSEP E+MQL+G+TVDY + + L+G
Sbjct: 275 LVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDP---------------HPGLQGGC 319
Query: 361 YFMNAVRDGESVLMGTTDENECHLWVMALYRATGQSHKPTP--------PTTSDTHHKIM 412
F NAV++G++V+ + DE + LWV A+YRATGQS+KP P P H
Sbjct: 320 MFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQ 379
Query: 413 GDADKARKHGMEDYIQADPCQFDHHQLFCTLQSLTLKYRLQDPYCSLGWFSPGQVFVLDE 472
AD+ +KHGM+++I A+PC+ DH LF LQ TL +RL D Y LGWFSPGQVFVLDE
Sbjct: 380 LYADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDE 439
Query: 473 YCARYGVRGCYRHLCYLSDLLDVAESGQQTVDPTLMHYSFAFCASHVHGNRVSPTGDVVH 532
YCARYGVRGC+RHLCYL++L++ +E+G +DPTL+HYSFAFCASHVHGNR
Sbjct: 440 YCARYGVRGCHRHLCYLAELMEHSENGA-VIDPTLLHYSFAFCASHVHGNR--------- 489
Query: 533 STATLPGRPDGVGSITVQEKEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGALKATLSL 592
PDG+G+++V+EKE+F EIKERL +LL++QI++FRY FPFGRPEGALKATLSL
Sbjct: 490 --------PDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSL 541
Query: 593 LERVLMKDVVTPVAPEEVRTMIQTSLENAALLNYTQLSQKANIEEDLRGDTMVTPAKKLE 652
LERVLMKD+ TP+ EEV+ +++ LE AAL+NYT+L++ A IEE + +PA+KLE
Sbjct: 542 LERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMN---QASPARKLE 598
Query: 653 DLIHLAELCVDLLQHNEEHYAEAFAWFSELLVEHAEIFWALFAVDMDRVLSEQPPDTWDS 712
+++HLAELC+++LQ NEEH+AEAFAW+ +LL EHAE FWALF VDMD L QP D+WDS
Sbjct: 599 EILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDS 658
Query: 713 FPLFQILNDYLRTDTDTEGTYPMDNLKGGRFHEHLRDTFAPLVVRYVDLMESSIAQSLHK 772
FPLFQ+LN++LR DT L G+FH+HL++ F PLVVRYVDLMESSIAQS+H+
Sbjct: 659 FPLFQLLNNFLRNDT---------LLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHR 709
Query: 773 GFEKERWEIKGNGCATSEELFWKLDALQCFIRDLHWPEPEFRSHLEQRLKLMASDMMETL 832
GFE+E W+ NG ATSE+LFWKLDALQ F+ DLHWPE EF HLEQRLKLMASDM+E
Sbjct: 710 GFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEAC 769
Query: 833 IQRTEAAFQSWLKKSVTFMSTDYILPAETCAMVNVALDAKNQALKLCAVEGVDIY----- 887
++RT AF+ L+K+ +TD +PA C M NV +DAK Q+ KLCA++G +
Sbjct: 770 VKRTRTAFELKLQKA--SKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGSQWQ 827
Query: 888 QYHAKMDGQIEACLVAMATGMTTRLSAVLEATLAKIARFDEGSLIGSILTI--------A 939
QYH+K+D I+ + + + + ++ +VLE L+K++R+DEG+ SIL+
Sbjct: 828 QYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYV 887
Query: 940 NVSGSGKDIGQGYVNFMRNSMDQIRSKVTDELWILQLFEQWYGNQVTMINNWLSER--PA 997
+V G D+ Y+ F+R + D +R KV +E++I +LF+QWY + + +I WL++R
Sbjct: 888 DVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQ 947
Query: 998 LHPHQVACLSILLKKMYSDFELQGVIDDKLNSKTYQGVAARMHTEEAT 1045
LH +Q+ L ++KK Y DF LQGV++ LNSKTY V R+ EEAT
Sbjct: 948 LHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEAT 995
>AF401638-1|AAN38707.1| 1254|Homo sapiens CADPS2 protein.
Length = 1254
Score = 1157 bits (2865), Expect = 0.0
Identities = 586/1068 (54%), Positives = 761/1068 (71%), Gaps = 100/1068 (9%)
Query: 1 MFQQILGVKKFEHQLLFNALLLDSADEQAAAIRRELDGRMQKVNEMEKNRKLMPKFVLKE 60
MFQQILG+KK EHQLL+NA LD+ADEQAA IRRELDGR+Q ++M K RK PKF+ K+
Sbjct: 241 MFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKF-PKFIAKD 299
Query: 61 MESLYIEELKSSINLLMANLESLPVSKGGADSKYGLHKIKRYNHRSNAGPDPSPRLSKQL 120
ME++YIEEL+SS+NLLMANLESLPVSKGG + K L K+KR S+
Sbjct: 300 MENMYIEELRSSVNLLMANLESLPVSKGGPEFK--LQKLKR---------------SQNS 342
Query: 121 CFRSQGSLANKLTGETDGEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLAPNRIVYCTMEV 180
F G E + QL+K DVVL+F +E+V+MEV+GLKS+APNRIVYCTMEV
Sbjct: 343 AFLDIGD-----------ENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEV 391
Query: 181 EGGDKLQTDQAEASKPMWDTQGDFSTTQPLPAVKVKLYTENPGVLALEDKELGKVVLRPT 240
EG +KLQTDQAEAS+P W TQGDF+TT P P VKVKL+TE+ GVLALEDKELG+V+L PT
Sbjct: 392 EG-EKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPT 450
Query: 241 PLSSKAPEWHRMTVPKNLPDQDLRIKIACRMDKPLNMKHCGYLHVIGKNVWRKWKRRYMV 300
SSK+ E HRM VPKN D DL+IK+A RMDKP ++KH GYL+ +G+ VW++WK+RY V
Sbjct: 451 SNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHIKHSGYLYALGQKVWKRWKKRYFV 510
Query: 301 LVQVSQYTFALCSYKDKKSEPAEMMQLDGFTVDYIELASAQLIVGQGKKENFNTKLEGAK 360
LVQVSQYTFA+CSY++KKSEP E+MQL+G+TVDY + + L+G
Sbjct: 511 LVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDP---------------HPGLQGGC 555
Query: 361 YFMNAVRDGESVLMGTTDENECHLWVMALYRATGQSHKPTP--------PTTSDTHHKIM 412
F NAV++G++V+ + DE + LWV A+YRATGQS+KP P P H
Sbjct: 556 MFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQ 615
Query: 413 GDADKARKHGMEDYIQADPCQFDHHQLFCTLQSLTLKYRLQDPYCSLGWFSPGQVFVLDE 472
AD+ +KHGM+++I A+PC+ DH LF LQ TL +RL D Y LGWFSPGQVFVLDE
Sbjct: 616 LYADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDE 675
Query: 473 YCARYGVRGCYRHLCYLSDLLDVAESGQQTVDPTLMHYSFAFCASHVHGNRVSPTGDVVH 532
YCARYGVRGC+RHLCYL++L++ +E+G +DPTL+HYSFAFCASHVHGNR
Sbjct: 676 YCARYGVRGCHRHLCYLAELMEHSENGA-VIDPTLLHYSFAFCASHVHGNR--------- 725
Query: 533 STATLPGRPDGVGSITVQEKEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGALKATLSL 592
PDG+G+++V+EKE+F EIKERL +LL++QI++FRY FPFGRPEGALKATLSL
Sbjct: 726 --------PDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKATLSL 777
Query: 593 LERVLMKDVVTPVAPEEVRTMIQTSLENAALLNYTQLSQKANIEEDLRGDTMVTPAKKLE 652
LERVLMKD+ TP+ EEV+ +++ LE AAL+NYT+L++ A IEE + +PA+KLE
Sbjct: 778 LERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMN---QASPARKLE 834
Query: 653 DLIHLAELCVDLLQHNEEHYAEAFAWFSELLVEHAEIFWALFAVDMDRVLSEQPPDTWDS 712
+++HLAELC+++LQ NEEH+AEAFAW+ +LL EHAE FWALF VDMD L QP D+WDS
Sbjct: 835 EILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDS 894
Query: 713 FPLFQILNDYLRTDTDTEGTYPMDNLKGGRFHEHLRDTFAPLVVRYVDLMESSIAQSLHK 772
FPLFQ+LN++LR DT L G+FH+HL++ F PLVVRYVDLMESSIAQS+H+
Sbjct: 895 FPLFQLLNNFLRNDT---------LLCNGKFHKHLQEIFVPLVVRYVDLMESSIAQSIHR 945
Query: 773 GFEKERWEIKGNGCATSEELFWKLDALQCFIRDLHWPEPEFRSHLEQRLKLMASDMMETL 832
GFE+E W+ NG ATSE+LFWKLDALQ F+ DLHWPE EF HLEQRLKLMASDM+E
Sbjct: 946 GFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEAC 1005
Query: 833 IQRTEAAFQSWLKKSVTFMSTDYILPAETCAMVNVALDAKNQALKLCAVEGVDIY----- 887
++RT AF+ L+K+ +TD +PA C M NV +DAK Q+ KLCA++G +
Sbjct: 1006 VKRTRTAFELKLQKA--SKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEFGSQWQ 1063
Query: 888 QYHAKMDGQIEACLVAMATGMTTRLSAVLEATLAKIARFDEGSLIGSILTI--------A 939
QYH+K+D I+ + + + + ++ +VLE L+K++R+DEG+ SIL+
Sbjct: 1064 QYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYV 1123
Query: 940 NVSGSGKDIGQGYVNFMRNSMDQIRSKVTDELWILQLFEQWYGNQVTMINNWLSER--PA 997
+V G D+ Y+ F+R + D +R KV +E++I +LF+QWY + + +I WL++R
Sbjct: 1124 DVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQ 1183
Query: 998 LHPHQVACLSILLKKMYSDFELQGVIDDKLNSKTYQGVAARMHTEEAT 1045
LH +Q+ L ++KK Y DF LQGV++ LNSKTY V R+ EEAT
Sbjct: 1184 LHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEAT 1231
>AK025672-1|BAB15210.1| 879|Homo sapiens protein ( Homo sapiens cDNA:
FLJ22019 fis, clone HEP07982. ).
Length = 879
Score = 1026 bits (2540), Expect = 0.0
Identities = 502/904 (55%), Positives = 654/904 (72%), Gaps = 66/904 (7%)
Query: 160 MEVKGLKSLAPNRIVYCTMEVEGGDKLQTDQAEASKPMWDTQGDFSTTQPLPAVKVKLYT 219
MEV+GLKS+APNRIVYCTMEVEG +KLQTDQAEAS+P W TQGDF+TT P P VKVKL+T
Sbjct: 1 MEVQGLKSVAPNRIVYCTMEVEG-EKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFT 59
Query: 220 ENPGVLALEDKELGKVVLRPTPLSSKAPEWHRMTVPKNLPDQDLRIKIACRMDKPLNMKH 279
E+ GVLALEDKELG+V+L PT SSK+ E HRM VPKN D DL+IK+A RMDKP +MKH
Sbjct: 60 ESTGVLALEDKELGRVILYPTSNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKH 119
Query: 280 CGYLHVIGKNVWRKWKRRYMVLVQVSQYTFALCSYKDKKSEPAEMMQLDGFTVDYIELAS 339
GYL+ +G+ VW++WK+RY VLVQVSQYTFA+CSY++KKSEP E+MQL+G+TVDY +
Sbjct: 120 SGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDP-- 177
Query: 340 AQLIVGQGKKENFNTKLEGAKYFMNAVRDGESVLMGTTDENECHLWVMALYRATGQSHKP 399
+ L+G F NAV++G++V+ + DE + LWV A+YRATGQS+KP
Sbjct: 178 -------------HPGLQGGCMFFNAVKEGDTVIFASDDEQDRVLWVQAMYRATGQSYKP 224
Query: 400 TP--------PTTSDTHHKIMGDADKARKHGMEDYIQADPCQFDHHQLFCTLQSLTLKYR 451
P P H AD+ +KHGM+++I A+PC+ DH LF LQ TL +R
Sbjct: 225 VPAIQTQKLNPKGGTLHADAQLYADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHR 284
Query: 452 LQDPYCSLGWFSPGQVFVLDEYCARYGVRGCYRHLCYLSDLLDVAESGQQTVDPTLMHYS 511
L D Y LGWFSPGQVFVLDEYCARYGVRGC+RHLCYL++L++ +E+G +DPTL+HYS
Sbjct: 285 LNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLAELMEHSENGA-VIDPTLLHYS 343
Query: 512 FAFCASHVHGNRVSPTGDVVHSTATLPGRPDGVGSITVQEKEKFAEIKERLKTLLQHQIT 571
FAFCASHVHGNR PDG+G+++V+EKE+F EIKERL +LL++QI+
Sbjct: 344 FAFCASHVHGNR-----------------PDGIGTVSVEEKERFEEIKERLSSLLENQIS 386
Query: 572 NFRYAFPFGRPEGALKATLSLLERVLMKDVVTPVAPEEVRTMIQTSLENAALLNYTQLSQ 631
+FRY FPFGRPEGALKATLSLLERVLMKD+ TP+ EEV+ +++ LE AAL+NYT+L++
Sbjct: 387 HFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTE 446
Query: 632 KANIEEDLRGDTMVTPAKKLEDLIHLAELCVDLLQHNEEHYAEAFAWFSELLVEHAEIFW 691
A IEE + +PA+KLE+++HLAELC+++LQ NEEH+AEAFAW+ +LL EHAE FW
Sbjct: 447 YAKIEETMN---QASPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFW 503
Query: 692 ALFAVDMDRVLSEQPPDTWDSFPLFQILNDYLRTDTDTEGTYPMDNLKGGRFHEHLRDTF 751
ALF VDMD L QP D+WDSFPLFQ+LN++LR DT L G+FH+HL++ F
Sbjct: 504 ALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDT---------LLCNGKFHKHLQEIF 554
Query: 752 APLVVRYVDLMESSIAQSLHKGFEKERWEIKGNGCATSEELFWKLDALQCFIRDLHWPEP 811
PLVVRYVDLMESSIAQS+H+GFE+E W+ NG ATSE+LFWKLDALQ F+ DLHWPE
Sbjct: 555 VPLVVRYVDLMESSIAQSIHRGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWPEQ 614
Query: 812 EFRSHLEQRLKLMASDMMETLIQRTEAAFQSWLKKSVTFMSTDYILPAETCAMVNVALDA 871
EF HLEQRLKLMASDM+E ++RT AF+ L+K+ +TD +PA C M NV +DA
Sbjct: 615 EFAHHLEQRLKLMASDMLEACVKRTRTAFELKLQKA--GKTTDLRIPASVCTMFNVLVDA 672
Query: 872 KNQALKLCAVEGVDIYQYHAKMDGQIEACLVAMATGMTTRLSAVLEATLAKIARFDEGSL 931
K Q+ KLCA++G QYH+K+D I+ + + + + ++ +VLE L+K++R+DEG+
Sbjct: 673 KKQSTKLCALDGGQEQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTF 732
Query: 932 IGSILTI--------ANVSGSGKDIGQGYVNFMRNSMDQIRSKVTDELWILQLFEQWYGN 983
SIL+ +V G D+ Y+ F+R + D +R KV +E++I +LF+QWY +
Sbjct: 733 FSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSS 792
Query: 984 QVTMINNWLSER--PALHPHQVACLSILLKKMYSDFELQGVIDDKLNSKTYQGVAARMHT 1041
+ +I WL++R LH +Q+ L ++KK Y DF LQGV++ LNSKTY V R+
Sbjct: 793 SMKVICVWLTDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTV 852
Query: 1042 EEAT 1045
EEAT
Sbjct: 853 EEAT 856
>AB032947-1|BAA86435.2| 1390|Homo sapiens KIAA1121 protein protein.
Length = 1390
Score = 960 bits (2377), Expect = 0.0
Identities = 492/803 (61%), Positives = 599/803 (74%), Gaps = 95/803 (11%)
Query: 1 MFQQILGVKKFEHQLLFNALLLDSADEQAAAIRRELDGRMQKVNEMEKNRKLMPKFVLKE 60
MFQ ILG+KKFEHQLL+NA LD+ DEQAA IRRELDGR+Q +++ + RK PKFV KE
Sbjct: 313 MFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQMADQIARERKF-PKFVSKE 371
Query: 61 MESLYIEELKSSINLLMANLESLPVSKGGADSKYGLHKIKRYNHRSNAGPDPSPRLSKQL 120
ME++YIEELKSS+NLLMANLES+PVSKGG ++ L K+KR +H +
Sbjct: 372 MENMYIEELKSSVNLLMANLESMPVSKGG---EFKLQKLKR-SHNA-------------- 413
Query: 121 CFRSQGSLANKLTGETDGEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLAPNRIVYCTMEV 180
S+ + GE E + QL+K DVVL+F +EVV+MEV+GLKSLAPNRIVYCTMEV
Sbjct: 414 ------SIIDM--GE---ESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVYCTMEV 462
Query: 181 EGGDKLQTDQAEASKPMWDTQGDFSTTQPLPAVKVKLYTENPGVLALEDKELGKVVLRPT 240
EGG+KLQTDQAEASKP W TQGDFSTT LPAVKVKL+TE+ GVLALEDKELG+V+L PT
Sbjct: 463 EGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPT 522
Query: 241 PLSSKAPEWHRMTVPKNLPDQDLRIKIACRMDKPLNMKHCGYLHVIGKNVWRKWKRRYMV 300
P S K EWH+MTV KN PDQDL+IK+A RMDKP NMKH GYL IGKNVW++WK+R+ V
Sbjct: 523 PNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWKKRFFV 582
Query: 301 LVQVSQYTFALCSYKDKKSEPAEMMQLDGFTVDYIELASAQLIVGQGKKENFNTKLEGAK 360
LVQVSQYTFA+CSY++KK+EP E++QLDG+TVDY + LEG +
Sbjct: 583 LVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPG---------------LEGGR 627
Query: 361 YFMNAVRDGESVLMGTTDENECHLWVMALYRATGQSHKPTPPTTSDTHHKIMGD------ 414
F NAV++G++V+ + DE + LWV A+YRATGQSHKP PPT + G+
Sbjct: 628 AFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDA 687
Query: 415 ------ADKARKHGMEDYIQADPCQFDHHQLFCTLQSLTLKYRLQDPYCSLGWFSPGQVF 468
AD+A+KHGM+++I ++PC FDH LF +Q LTL +RL D Y LGWFSPGQVF
Sbjct: 688 PISQFYADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVF 747
Query: 469 VLDEYCARYGVRGCYRHLCYLSDLLDVAESGQQTVDPTLMHYSFAFCASHVHGNRVSPTG 528
VLDEYCAR GVRGC+RHLCYL DLL+ AE+G +DPTL+HYSFAFCASHVHGN
Sbjct: 748 VLDEYCARNGVRGCHRHLCYLRDLLERAENGAM-IDPTLLHYSFAFCASHVHGN------ 800
Query: 529 DVVHSTATLPGRPDGVGSITVQEKEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGALKA 588
RPDG+G++TV+EKE+F EIKERL+ LL++QIT+FRY FPFGRPEGALKA
Sbjct: 801 -----------RPDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKA 849
Query: 589 TLSLLERVLMKDVVTPVAPEEVRTMIQTSLENAALLNYTQLSQKANIEEDLRG----DTM 644
TLSLLERVLMKD+VTPV EEV+T+I+ LE AAL+NY++LS+ A IEE+ + +
Sbjct: 850 TLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEENQKDAENVGRL 909
Query: 645 VTPAKKLEDLIHLAELCVDLLQHNEEHYA-------EAFAWFSELLVEHAEIFWALFAVD 697
+TPAKKLED I LAEL +++LQ NEEH+A EAFAW+S+L+VEHAE F +LFAVD
Sbjct: 910 ITPAKKLEDTIRLAELVIEVLQQNEEHHAEPHVDKGEAFAWWSDLMVEHAETFLSLFAVD 969
Query: 698 MDRVLSEQPPDTWDSFPLFQILNDYLRTDTDTEGTYPMDNLKGGRFHEHLRDTFAPLVVR 757
MD L QPPDTWDSFPLFQ+LND+LRTD NL G+FH+HL+D FAPLVVR
Sbjct: 970 MDAALEVQPPDTWDSFPLFQLLNDFLRTDY---------NLCNGKFHKHLQDLFAPLVVR 1020
Query: 758 YVDLMESSIAQSLHKGFEKERWE 780
YVDLMESSIAQS+H+GFE+E WE
Sbjct: 1021 YVDLMESSIAQSIHRGFERESWE 1043
Score = 260 bits (637), Expect = 2e-68
Identities = 131/272 (48%), Positives = 179/272 (65%), Gaps = 12/272 (4%)
Query: 784 NGCATSEELFWKLDALQCFIRDLHWPEPEFRSHLEQRLKLMASDMMETLIQRTEAAFQSW 843
NG TSE+LFWKLDALQ FIRDLHWPE EF HLEQRLKLMASDM+E+ ++RT AF+
Sbjct: 1096 NGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVK 1155
Query: 844 LKKSVTFMSTDYILPAETCAMVNVALDAKNQALKLCAVEGVDIYQYHAKMDGQIEACLVA 903
L+K T STD+ +P C M NV +DAK Q+ KLC++E +QYH+K+D IE +
Sbjct: 1156 LQK--TSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKE 1213
Query: 904 MATGMTTRLSAVLEATLAKIARFDEGSLIGSILTI--------ANVSGSGKDIGQGYVNF 955
M T + + +LE LAK++R+DEG+L S L+ +V G D+ YV F
Sbjct: 1214 MITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTF 1273
Query: 956 MRNSMDQIRSKVTDELWILQLFEQWYGNQVTMINNWLSERP--ALHPHQVACLSILLKKM 1013
+R+S D +R KV +E++I +LF+QWY + + +I WL++R LH +Q+ L ++KK
Sbjct: 1274 VRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRVVKKT 1333
Query: 1014 YSDFELQGVIDDKLNSKTYQGVAARMHTEEAT 1045
Y DF LQGV+D LNSKTY+ + R+ EEAT
Sbjct: 1334 YRDFRLQGVLDSTLNSKTYETIRNRLTVEEAT 1365
>AY264289-1|AAP22132.1| 1296|Homo sapiens Ca2+-dependent activator
protein for secretion 2 protein.
Length = 1296
Score = 914 bits (2261), Expect = 0.0
Identities = 463/794 (58%), Positives = 585/794 (73%), Gaps = 89/794 (11%)
Query: 1 MFQQILGVKKFEHQLLFNALLLDSADEQAAAIRRELDGRMQKVNEMEKNRKLMPKFVLKE 60
MFQQILG+KK EHQLL+NA LD+ADEQAA IRRELDGR+Q ++M K RK PKF+ K+
Sbjct: 242 MFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKF-PKFIAKD 300
Query: 61 MESLYIEELKSSINLLMANLESLPVSKGGADSKYGLHKIKRYNHRSNAGPDPSPRLSKQL 120
ME++YIEEL+SS+NLLMANLESLPVSKGG + K L K+KR S+
Sbjct: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFK--LQKLKR---------------SQNS 343
Query: 121 CFRSQGSLANKLTGETDGEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLAPNRIVYCTMEV 180
F G E + QL+K VVL+F +E+V+MEV+GLKS+APNRIVYCTMEV
Sbjct: 344 AFLDIGD-----------ENEIQLSKSGVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEV 392
Query: 181 EGGDKLQTDQAEASKPMWDTQGDFSTTQPLPAVKVKLYTENPGVLALEDKELGKVVLRPT 240
EG +KLQTDQAEAS+P W TQGDF+TT P P VKVKL+TE+ GVLALEDKELG+V+L PT
Sbjct: 393 EG-EKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPT 451
Query: 241 PLSSKAPEWHRMTVPKNLPDQDLRIKIACRMDKPLNMKHCGYLHVIGKNVWRKWKRRYMV 300
SSK+ E HRM VPKN D DL+IK+A RMDKP +MKH GYL+ +G+ VW++WK+RY V
Sbjct: 452 SNSSKSAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFV 511
Query: 301 LVQVSQYTFALCSYKDKKSEPAEMMQLDGFTVDYIELASAQLIVGQGKKENFNTKLEGAK 360
LVQVSQYTFA+CSY++KKSEP E+MQL+G+TVDY + + L+G
Sbjct: 512 LVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDP---------------HPGLQGGC 556
Query: 361 YFMNAVRDGESVLMGTTDENECHLWVMALYRATGQSHKPTP--------PTTSDTH--HK 410
F NAV++G++V+ + DE + LWV A+YRATGQS+KP P P H +
Sbjct: 557 MFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAIQTQKLNPKGGTLHADAQ 616
Query: 411 IMG-DADKARKHGMEDYIQADPCQFDHHQLFCTLQSLTLKYRLQDPYCSLGWFSPGQVFV 469
+ G DAD+ +KHGM+++I A+PC+ DH LF LQ TL +RL D Y LGWFSPGQVFV
Sbjct: 617 LSGKDADRFQKHGMDEFISANPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFV 676
Query: 470 LDEYCARYGVRGCYRHLCYLSDLLDVAESGQQTVDPTLMHYSFAFCASHVHGNRVSPTGD 529
LDEYCARYGVRGC+RHLCYL++L++ +E+G +DPTL+HYSFAFCASHVHGN
Sbjct: 677 LDEYCARYGVRGCHRHLCYLAELMEHSENG-AVIDPTLLHYSFAFCASHVHGN------- 728
Query: 530 VVHSTATLPGRPDGVGSITVQEKEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGALKAT 589
RPDG+G+++V+EKE+F EIKERL +LL++QI++FRY FPFGRPEGALKAT
Sbjct: 729 ----------RPDGIGTVSVEEKERFEEIKERLSSLLENQISHFRYCFPFGRPEGALKAT 778
Query: 590 LSLLERVLMKDVVTPVAPEEVRTMIQTSLENAALLNYTQLSQKANIEEDLRGDTMVTPAK 649
LSLLERVLMKD+ TP+ EEV+ +++ LE AAL+NYT+L++ A IEE + +PA+
Sbjct: 779 LSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETM---NQASPAR 835
Query: 650 KLEDLIHLAELCVDLLQHNEEHYA---EAFAWFSELLVEHAEIFWALFAVDMDRVLSEQP 706
KLE+++HLAELC+++LQ NEEH+A EAFAW+ +LL EHAE FWALF VDMD L QP
Sbjct: 836 KLEEILHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQP 895
Query: 707 PDTWDSFPLFQILNDYLRTDTDTEGTYPMDNLKGGRFHEHLRDTFAPLVVRYVDLMESSI 766
D+WDSFPLFQ+LN++LR DT L G+FH+HL++ F PLVVRYVDLMESSI
Sbjct: 896 QDSWDSFPLFQLLNNFLRNDT---------LLCNGKFHKHLQEIFVPLVVRYVDLMESSI 946
Query: 767 AQSLHKGFEKERWE 780
AQS+H+GFE+E W+
Sbjct: 947 AQSIHRGFEQETWQ 960
Score = 247 bits (605), Expect = 1e-64
Identities = 125/272 (45%), Positives = 178/272 (65%), Gaps = 12/272 (4%)
Query: 784 NGCATSEELFWKLDALQCFIRDLHWPEPEFRSHLEQRLKLMASDMMETLIQRTEAAFQSW 843
NG ATSE+LFWKLDALQ F+ DLHWPE EF HLEQRLKLMASDM+E ++RT AF+
Sbjct: 1004 NGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMLEACVKRTRTAFELK 1063
Query: 844 LKKSVTFMSTDYILPAETCAMVNVALDAKNQALKLCAVEGVDIYQYHAKMDGQIEACLVA 903
L+K+ +TD +PA C M NV +DAK Q+ KLCA++G QYH+K+D I+ +
Sbjct: 1064 LQKA--SKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNSVKE 1121
Query: 904 MATGMTTRLSAVLEATLAKIARFDEGSLIGSILTI--------ANVSGSGKDIGQGYVNF 955
+ + + ++ +VLE L+K++R+DEG+ SIL+ +V G D+ Y+ F
Sbjct: 1122 IISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMF 1181
Query: 956 MRNSMDQIRSKVTDELWILQLFEQWYGNQVTMINNWLSER--PALHPHQVACLSILLKKM 1013
+R + D +R KV +E++I +LF+QWY + + +I WL++R LH +Q+ L ++KK
Sbjct: 1182 VRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWLTDRLDLQLHIYQLKTLIKIVKKT 1241
Query: 1014 YSDFELQGVIDDKLNSKTYQGVAARMHTEEAT 1045
Y DF LQGV++ LNSKTY V R+ EEAT
Sbjct: 1242 YRDFRLQGVLEGTLNSKTYDTVHRRLTVEEAT 1273
>BC131731-1|AAI31732.1| 776|Homo sapiens CADPS protein protein.
Length = 776
Score = 889 bits (2200), Expect = 0.0
Identities = 444/795 (55%), Positives = 565/795 (71%), Gaps = 70/795 (8%)
Query: 277 MKHCGYLHVIGKNVWRKWKRRYMVLVQVSQYTFALCSYKDKKSEPAEMMQLDGFTVDYIE 336
MKH GYL IGKNVW++WK+R+ VLVQVSQYTFA+CSY++KK+EP E++QLDG+TVDY +
Sbjct: 1 MKHSGYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTD 60
Query: 337 LASAQLIVGQGKKENFNTKLEGAKYFMNAVRDGESVLMGTTDENECHLWVMALYRATGQS 396
LEG + F NAV++G++V+ + DE + LWV A+YRATGQS
Sbjct: 61 PQPG---------------LEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQS 105
Query: 397 HKPTPPTTSDTHHKIMGD------------ADKARKHGMEDYIQADPCQFDHHQLFCTLQ 444
HKP PPT + G+ AD+A+KHGM+++I ++PC FDH LF +Q
Sbjct: 106 HKPVPPTQVQKLNAKGGNVPQLDAPISQFYADRAQKHGMDEFISSNPCNFDHASLFEMVQ 165
Query: 445 SLTLKYRLQDPYCSLGWFSPGQVFVLDEYCARYGVRGCYRHLCYLSDLLDVAESGQQTVD 504
LTL +RL D Y LGWFSPGQVFVLDEYCAR GVRGC+RHLCYL DLL+ AE+G +D
Sbjct: 166 RLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAM-ID 224
Query: 505 PTLMHYSFAFCASHVHGNRVSPTGDVVHSTATLPGRPDGVGSITVQEKEKFAEIKERLKT 564
PTL+HYSFAFCASHVHGNR PDG+G++TV+EKE+F EIKERL+
Sbjct: 225 PTLLHYSFAFCASHVHGNR-----------------PDGIGTVTVEEKERFEEIKERLRV 267
Query: 565 LLQHQITNFRYAFPFGRPEGALKATLSLLERVLMKDVVTPVAPEEVRTMIQTSLENAALL 624
LL++QIT+FRY FPFGRPEGALKATLSLLERVLMKD+VTPV EEV+T+I+ LE AAL+
Sbjct: 268 LLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALV 327
Query: 625 NYTQLSQKANIEEDLRG----DTMVTPAKKLEDLIHLAELCVDLLQHNEEHYAEAFAWFS 680
NY++LS+ A IEE+ + ++TPAKKLED I LAEL +++LQ NEEH+AEAFAW+S
Sbjct: 328 NYSRLSEYAKIEENQKDAENVGRLITPAKKLEDTIRLAELVIEVLQQNEEHHAEAFAWWS 387
Query: 681 ELLVEHAEIFWALFAVDMDRVLSEQPPDTWDSFPLFQILNDYLRTDTDTEGTYPMDNLKG 740
+L+VEHAE F +LFAVDMD L QPPDTWDSFPLFQ+LND+LRTD NL
Sbjct: 388 DLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDY---------NLCN 438
Query: 741 GRFHEHLRDTFAPLVVRYVDLMESSIAQSLHKGFEKERWEIKGNGCATSEELFWKLDALQ 800
G+FH+HL+D FAPLVVRYVDLMESSIAQS+H+GFE+E WE NG TSE+LFWKLDALQ
Sbjct: 439 GKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVNNGSGTSEDLFWKLDALQ 498
Query: 801 CFIRDLHWPEPEFRSHLEQRLKLMASDMMETLIQRTEAAFQSWLKKSVTFMSTDYILPAE 860
FIRDLHWPE EF HLEQRLKLMASDM+E+ ++RT AF+ L+K T STD+ +P
Sbjct: 499 TFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQK--TSRSTDFRVPQS 556
Query: 861 TCAMVNVALDAKNQALKLCAVEGVDIYQYHAKMDGQIEACLVAMATGMTTRLSAVLEATL 920
C M NV +DAK Q+ KLC++E +QYH+K+D IE + M T + + +LE L
Sbjct: 557 ICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVL 616
Query: 921 AKIARFDEGSLIGSILTI--------ANVSGSGKDIGQGYVNFMRNSMDQIRSKVTDELW 972
AK++R+DEG+L S L+ +V G D+ YV F+R+S D +R KV E++
Sbjct: 617 AKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNGEMY 676
Query: 973 ILQLFEQWYGNQVTMINNWLSERP--ALHPHQVACLSILLKKMYSDFELQGVIDDKLNSK 1030
I +LF+QWY + + +I WL++R LH +Q+ L ++KK Y DF LQGV+D LNSK
Sbjct: 677 IERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSK 736
Query: 1031 TYQGVAARMHTEEAT 1045
TY+ + R+ EEAT
Sbjct: 737 TYETIRNRLTVEEAT 751
>AK000768-1|BAA91372.1| 431|Homo sapiens protein ( Homo sapiens cDNA
FLJ20761 fis, clone HEP00317. ).
Length = 431
Score = 428 bits (1055), Expect = e-119
Identities = 211/415 (50%), Positives = 288/415 (69%), Gaps = 26/415 (6%)
Query: 646 TPAKKLEDLIHLAELCVDLLQHNEEHYAEAFAWFSELLVEHAEIFWALFAVDMDRVLSEQ 705
+PA+KLE+++HLAELC+++LQ NEEH+AEAFAW+ +LL EHAE FWALF VDMD L Q
Sbjct: 5 SPARKLEEILHLAELCIEVLQQNEEHHAEAFAWWPDLLAEHAEKFWALFTVDMDTALEAQ 64
Query: 706 PPDTWDSFPLFQILNDYLRTDTDTEGTYPMDNLKGGRFHEHLRDTFAPLVVRYVDLMESS 765
P D+WDSFPLFQ+LN++LR DT L G+FH+HL++ F PLVVRYVDLMESS
Sbjct: 65 PQDSWDSFPLFQLLNNFLRNDT---------LLCNGKFHKHLQEIFVPLVVRYVDLMESS 115
Query: 766 IAQSLHKGFEKERWEIKGNGCATSEELFWKLDALQCFIRDLHWPEPEFRSHLEQRLKLMA 825
IAQS+H+GFE+E W+ NG ATSE+LFWKLDALQ F+ DLHWPE EF HLEQRLKLMA
Sbjct: 116 IAQSIHRGFEQETWQPVNNGSATSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMA 175
Query: 826 SDMMETLIQRTEAAFQSWLKKSVTFMSTDYILPAETCAMVNVALDAKNQALKLCAVEGVD 885
SDM+E ++RT AF+ L+K+ +TD +PA C M NV +DAK Q+ KLCA++G
Sbjct: 176 SDMLEACVKRTRTAFELKLQKA--SKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQ 233
Query: 886 IY-----QYHAKMDGQIEACLVAMATGMTTRLSAVLEATLAKIARFDEGSLIGSILTI-- 938
+ QYH+K+D I+ + + + + ++ +VLE L+K++R+DEG+ SIL+
Sbjct: 234 EFGSQWQQYHSKIDDLIDNSVKEIISLLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTV 293
Query: 939 ------ANVSGSGKDIGQGYVNFMRNSMDQIRSKVTDELWILQLFEQWYGNQVTMINNWL 992
+V G D+ Y+ F+R + D +R KV +E++I +LF+QWY + + +I WL
Sbjct: 294 KAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSSSMKVICVWL 353
Query: 993 SER--PALHPHQVACLSILLKKMYSDFELQGVIDDKLNSKTYQGVAARMHTEEAT 1045
++R LH +Q+ L ++KK Y DF LQGV++ LNSKTY V R+ EEAT
Sbjct: 354 TDRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTVHRRLTVEEAT 408
>AK098170-1|BAC05249.1| 550|Homo sapiens protein ( Homo sapiens
cDNA FLJ40851 fis, clone TRACH2014997, moderately
similar to Rattus norvegicus Ca2+-dependent activator
protein (CAPS) mRNA. ).
Length = 550
Score = 353 bits (867), Expect = 3e-96
Identities = 183/297 (61%), Positives = 222/297 (74%), Gaps = 30/297 (10%)
Query: 1 MFQQILGVKKFEHQLLFNALLLDSADEQAAAIRRELDGRMQKVNEMEKNRKLMPKFVLKE 60
MFQQILG+KK EHQLL+NA LD+ADEQAA IRRELDGR+Q ++M K RK PKF+ K+
Sbjct: 242 MFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLADKMAKERKF-PKFIAKD 300
Query: 61 MESLYIEELKSSINLLMANLESLPVSKGGADSKYGLHKIKRYNHRSNAGPDPSPRLSKQL 120
ME++YIEEL+SS+NLLMANLESLPVSKGG + K L K+KR S+
Sbjct: 301 MENMYIEELRSSVNLLMANLESLPVSKGGPEFK--LQKLKR---------------SQNS 343
Query: 121 CFRSQGSLANKLTGETDGEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLAPNRIVYCTMEV 180
F G E + QL+K DVVL+F +E+V+MEV+GLKS+APNRIVYCTMEV
Sbjct: 344 AFLDIGD-----------ENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEV 392
Query: 181 EGGDKLQTDQAEASKPMWDTQGDFSTTQPLPAVKVKLYTENPGVLALEDKELGKVVLRPT 240
EG +KLQTDQAEAS+P W TQGDF+TT P P VKVKL+TE+ GVLALEDKELG+V+L PT
Sbjct: 393 EG-EKLQTDQAEASRPQWGTQGDFTTTHPRPVVKVKLFTESTGVLALEDKELGRVILYPT 451
Query: 241 PLSSKAPEWHRMTVPKNLPDQDLRIKIACRMDKPLNMKHCGYLHVIGKNVWRKWKRR 297
SSK E HRM VPKN D DL+IK+A RMDKP +MKH GYL+ +G+ VW++WK+R
Sbjct: 452 SNSSKTAELHRMVVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKQR 508
>BC072684-1|AAH72684.1| 233|Homo sapiens CADPS protein protein.
Length = 233
Score = 169 bits (412), Expect = 4e-41
Identities = 86/207 (41%), Positives = 127/207 (61%), Gaps = 10/207 (4%)
Query: 849 TFMSTDYILPAETCAMVNVALDAKNQALKLCAVEGVDIYQYHAKMDGQIEACLVAMATGM 908
T STD+ +P C M NV +DAK Q+ KLC++E +QYH+K+D IE + M T +
Sbjct: 2 TSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLL 61
Query: 909 TTRLSAVLEATLAKIARFDEGSLIGSILTI--------ANVSGSGKDIGQGYVNFMRNSM 960
+ +LE LAK++R+DEG+L S L+ +V G D+ YV F+R+S
Sbjct: 62 VAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQ 121
Query: 961 DQIRSKVTDELWILQLFEQWYGNQVTMINNWLSERP--ALHPHQVACLSILLKKMYSDFE 1018
D +R KV +E++I +LF+QWY + + +I WL++R LH +Q+ L ++KK Y DF
Sbjct: 122 DVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFR 181
Query: 1019 LQGVIDDKLNSKTYQGVAARMHTEEAT 1045
LQGV+D LNSKTY+ + R+ EEAT
Sbjct: 182 LQGVLDSTLNSKTYETIRNRLTVEEAT 208
>BC015754-1|AAH15754.1| 222|Homo sapiens CADPS protein protein.
Length = 222
Score = 151 bits (367), Expect = 1e-35
Identities = 81/197 (41%), Positives = 121/197 (61%), Gaps = 15/197 (7%)
Query: 864 MVNVALDAKNQALKLCAVE-GVDI----YQYHAKMDGQIEACLVAMATGMTTRLSAVLEA 918
M NV +DAK Q+ KLC++E G + +QYH+K+D IE + M T + + +LE
Sbjct: 1 MFNVMVDAKAQSTKLCSMEMGQEFAKMWHQYHSKIDELIEETVKEMITLLVAKFVTILEG 60
Query: 919 TLAKIARFDEGSLIGSILTIA--------NVSGSGKDIGQGYVNFMRNSMDQIRSKVTDE 970
LAK++R+DEG+L S L+ +V G D+ YV F+R+S D +R KV +E
Sbjct: 61 VLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEE 120
Query: 971 LWILQLFEQWYGNQVTMINNWLSERP--ALHPHQVACLSILLKKMYSDFELQGVIDDKLN 1028
++I +LF+QWY + + +I WL++R LH +Q+ L ++KK Y DF LQGV+D LN
Sbjct: 121 MYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLN 180
Query: 1029 SKTYQGVAARMHTEEAT 1045
SKTY+ + R+ EEAT
Sbjct: 181 SKTYETIRNRLTVEEAT 197
>BC029460-1|AAH29460.1| 138|Homo sapiens CADPS protein protein.
Length = 138
Score = 145 bits (352), Expect = 7e-34
Identities = 88/152 (57%), Positives = 109/152 (71%), Gaps = 30/152 (19%)
Query: 45 EMEKNRKLMPKFVLKEMESLYIEELKSSINLLMANLESLPVSKGGADSKYGLHKIKRYNH 104
++ + RK PKFV KEME++YIEELKSS+NLLMANLES+PVSKGG ++ L K+KR +H
Sbjct: 1 QIARERKF-PKFVSKEMENMYIEELKSSVNLLMANLESMPVSKGG---EFKLQKLKR-SH 55
Query: 105 RSNAGPDPSPRLSKQLCFRSQGSLANKLTGETDGEVDTQLTKMDVVLTFQIEVVVMEVKG 164
+ S+ + GE E + QL+K DVVL+F +EVV+MEV+G
Sbjct: 56 NA--------------------SIIDM--GE---ESENQLSKSDVVLSFSLEVVIMEVQG 90
Query: 165 LKSLAPNRIVYCTMEVEGGDKLQTDQAEASKP 196
LKSLAPNRIVYCTMEVEGG+KLQTDQAEASKP
Sbjct: 91 LKSLAPNRIVYCTMEVEGGEKLQTDQAEASKP 122
>U36448-1|AAA79701.1| 223|Homo sapiens Ca2+-dependent activator
protein for secretion protein.
Length = 223
Score = 123 bits (296), Expect = 4e-27
Identities = 74/198 (37%), Positives = 113/198 (57%), Gaps = 16/198 (8%)
Query: 864 MVNVALDAKNQALKLCAVE-GVDI----YQYHAKMDGQIEACLVAMATGMTTRLSAVLEA 918
M NV +DAK Q+ KLC++E G + +QYH+K+D IE + M T + + +LE
Sbjct: 1 MFNVMVDAKAQSTKLCSMEMGQEFAKMWHQYHSKIDELIEETVKEMITLLVAKFVTILEG 60
Query: 919 TLAKIARFDEGSLIGSILTIA--------NVSGSGKDIGQGYVNFMRNSMDQIRSKVTDE 970
LAK+ R+DEG+L S L+ +V G D+ YV F R+S D +R KV +E
Sbjct: 61 VLAKLYRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVPDAYVTFGRHSQDVLRDKVNEE 120
Query: 971 LWILQLFEQWYGNQVTMINNWLSERP--ALHPHQVACLSILLKKMYSDFELQGVIDDKL- 1027
++I +LF+QWY + + +I WL++R LH +Q+ L ++KK Y DF LQG L
Sbjct: 121 MYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGGPGLHLK 180
Query: 1028 NSKTYQGVAARMHTEEAT 1045
++ + + R+ EEAT
Sbjct: 181 QARPDEPIRNRLTVEEAT 198
>AK127506-1|BAC87012.1| 151|Homo sapiens protein ( Homo sapiens cDNA
FLJ45599 fis, clone BRTHA3019183, highly similar to Mus
musculus Ca<2+>dependent activator protein for secretion
(Cadps). ).
Length = 151
Score = 103 bits (246), Expect = 5e-21
Identities = 47/103 (45%), Positives = 69/103 (66%), Gaps = 2/103 (1%)
Query: 945 GKDIGQGYVNFMRNSMDQIRSKVTDELWILQLFEQWYGNQVTMINNWLSERP--ALHPHQ 1002
G D+ YV F+R+S D +R KV +E++I +LF+QWY + + +I WL++R LH +Q
Sbjct: 24 GMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQ 83
Query: 1003 VACLSILLKKMYSDFELQGVIDDKLNSKTYQGVAARMHTEEAT 1045
+ L ++KK Y DF LQGV+D LNSKTY+ + R+ EEAT
Sbjct: 84 LKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEAT 126
>BC111800-1|AAI11801.1| 1197|Homo sapiens UNC13B protein protein.
Length = 1197
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 441 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 500
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 501 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 560
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 561 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 612
>BC111781-1|AAI11782.1| 1610|Homo sapiens UNC13B protein protein.
Length = 1610
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 854 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 913
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 914 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 973
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 974 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1025
>AL354669-2|CAH71208.1| 1591|Homo sapiens unc-13 homolog B (C.
elegans) protein.
Length = 1591
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 854 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 913
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 914 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 973
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 974 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1025
>AL354669-1|CAH71207.1| 1622|Homo sapiens unc-13 homolog B (C.
elegans) protein.
Length = 1622
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 866 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 925
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 926 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 985
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 986 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1037
>AL353795-12|CAH71004.1| 1591|Homo sapiens unc-13 homolog B (C.
elegans) protein.
Length = 1591
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 854 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 913
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 914 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 973
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 974 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1025
>AL353795-11|CAH71003.1| 1622|Homo sapiens unc-13 homolog B (C.
elegans) protein.
Length = 1622
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 866 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 925
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 926 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 985
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 986 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1037
>AL160274-2|CAH73361.1| 1591|Homo sapiens unc-13 homolog B (C.
elegans) protein.
Length = 1591
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 854 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 913
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 914 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 973
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 974 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1025
>AL160274-1|CAH73362.1| 1622|Homo sapiens unc-13 homolog B (C.
elegans) protein.
Length = 1622
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 866 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 925
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 926 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 985
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 986 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1037
>AF020202-1|AAC19406.1| 1591|Homo sapiens Munc13 protein.
Length = 1591
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 854 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 913
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 914 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 973
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 974 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1025
>AB209998-1|BAE06080.1| 1620|Homo sapiens UNC13B variant protein
protein.
Length = 1620
Score = 48.0 bits (109), Expect = 2e-04
Identities = 44/172 (25%), Positives = 83/172 (48%), Gaps = 15/172 (8%)
Query: 552 KEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA--LKATLSLLE-----RVLMKDVVTP 604
KE+F ++ ++L L+ ++ +R FP G PE LK+T+ LL R+ ++++ +P
Sbjct: 883 KERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSP 942
Query: 605 V-APEEVRTMIQTSLENA--ALLN--YTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAE 659
A + V+ ++ L + + N + S++ ++++L + + L+ L
Sbjct: 943 PRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLKQELPPEEQGPSIRNLDFWPKLIT 1002
Query: 660 LCVDLLQHNEEHYAEAFAWF-SELLV--EHAEIFWALFAVDMDRVLSEQPPD 708
L V +++ ++ Y F EL V AE+ W LFA DM L E D
Sbjct: 1003 LIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKD 1054
>AK091491-1|BAC03675.1| 891|Homo sapiens protein ( Homo sapiens
cDNA FLJ34172 fis, clone FCBBF3015758, highly similar to
Rattus norvegicus Munc13-3 mRNA. ).
Length = 891
Score = 44.8 bits (101), Expect = 0.002
Identities = 92/392 (23%), Positives = 156/392 (39%), Gaps = 56/392 (14%)
Query: 461 WFSPGQVFVLDEYCARYGVRGCYRHLCYLSDLLDVAES-GQQTVDPTLMHYSFAFCASHV 519
+F ++DE+ RYG+ Y+ + + S L G V TL+ AF A
Sbjct: 363 FFDDASQEIVDEFAMRYGIESIYQAMTHFSCLSSKYMCPGVPAVMSTLLANINAFYAHTT 422
Query: 520 HGNRVSPTGDVVHSTATLPGRPDGVGSITVQEKEKFAEIKERLKTLLQHQITNFRYAFPF 579
+ + AT GR EKF ++ ++L L+ ++ +R FP
Sbjct: 423 VSTNIQVSASD-RFAATNFGR------------EKFIKLLDQLHNSLRIDLSKYRENFPA 469
Query: 580 GRPEGA--LKATLSLLE-----RVLMKDVVTP-----VAPEEVRTMIQTS----LENAAL 623
E LK+T+ LL R+ + ++ +P V + VR + ++ +N
Sbjct: 470 SNTERLQDLKSTVDLLTSITFFRMKVLELQSPPKASMVVKDCVRACLDSTYKYIFDNCHE 529
Query: 624 LNYTQLSQKANIEEDLRGDTMVTPAKKLEDLIHLAELCVDLLQHNEEHYAEAFAWFSELL 683
L Y+QL+ + ++ R D T K L+ L L V ++ ++ Y F + L
Sbjct: 530 L-YSQLTDPSKKQDIPREDQGPT-TKNLDFWPQLITLMVTIIDEDKTAYTPVLNQFPQEL 587
Query: 684 VE---HAEIFWALFAVDMDRVLSEQPPDTWDSFPLFQILNDYLRTDTDTEGTYPMDNLKG 740
AEI W LFA+DM L E ++ L + DY+ + Y +
Sbjct: 588 NMGKISAEIMWTLFALDMKYALEEH-----ENQRLCK-STDYMNLHFKVKWFYNEYVREL 641
Query: 741 GRFHEHLRD---TFAPLVVRYVDLMESSIAQSLHKGFEKERWEIKGNGCATSEELFWKLD 797
F + + + F P V++++D E + LH +++ K TSE +
Sbjct: 642 PAFKDAVPEYSLWFEPFVMQWLDENEDVSMEFLHGALGRDK---KDGFQQTSEHALFSCS 698
Query: 798 ALQCF---------IRDLHWPEPEFRSHLEQR 820
+ F I+ L P PE SHL +R
Sbjct: 699 VVDVFAQLNQSFEIIKKLECPNPEALSHLMRR 730
>AB028955-1|BAA82984.2| 1702|Homo sapiens KIAA1032 protein protein.
Length = 1702
Score = 44.0 bits (99), Expect = 0.003
Identities = 89/410 (21%), Positives = 155/410 (37%), Gaps = 56/410 (13%)
Query: 469 VLDEYCARYGVRGCYRHLCYLSDLLDVAES-GQQTVDPTLMHYSFAFCASHVHGNRVSPT 527
++DE+ RYGV Y+ + + + L G V TL+ A+ A VS +
Sbjct: 860 IVDEFAMRYGVESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSAS 919
Query: 528 GDVVHSTATLPGRPDGVGSITVQEKEKFAEIKERLKTLLQHQITNFRYAFPFGRPEGA-- 585
S KE+F ++ ++L L+ ++ +R FP PE
Sbjct: 920 DRFAASNFG---------------KERFVKLLDQLHNSLRIDLSMYRNNFPASSPERLQD 964
Query: 586 LKATLSLLE-----RVLMKDVVTPV-APEEVRTMIQTSLENAA--LLNYTQLSQKANIEE 637
LK+T+ LL R+ ++++ +P A + V+ ++ L + + N +
Sbjct: 965 LKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHELYSREYQT 1024
Query: 638 DLRGDTMVTPA------KKLEDLIHLAELCVDLLQHNEEHYAEAFAWF-SELLVEH--AE 688
D V P K L+ L L V +++ ++ Y F EL V AE
Sbjct: 1025 DPAKKGEVPPEEQGPSIKNLDFWSKLITLIVSIIEEDKNSYTPCLNQFPQELNVGKISAE 1084
Query: 689 IFWALFAVDMDRVLSEQPPDTWDSFPLFQILNDYLRTDTDTEGTYPMDNLKGGRFHEHLR 748
+ W LFA DM + E D L + DY+ + Y + F + +
Sbjct: 1085 VMWNLFAQDMKYAMEEH-----DKHRLCKSA-DYMNLHFKVKWLYNEYVTELPAFKDRVP 1138
Query: 749 D---TFAPLVVRYVDLMESSIAQSLHKGFEKERWEIKGNGCATSEELFWKLDALQCF--- 802
+ F P V++++D E LH E+++ K TSE + + F
Sbjct: 1139 EYPAWFEPFVIQWLDENEEVSRDFLHGALERDK---KDGFQQTSEHALFSCSVVDVFSQL 1195
Query: 803 ------IRDLHWPEPEFRSHLEQRLKLMASDMMETLIQRTEAAFQSWLKK 846
I+ L P+P+ H +R S+++ F S+ K
Sbjct: 1196 NQSFEIIKKLECPDPQIVGHYMRRFAKTISNVLLQYADIISKDFASYCSK 1245
>U10886-1|AAB36687.1| 1337|Homo sapiens density enhanced
phosphatase-1 protein.
Length = 1337
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 111 DPSPRLSKQLCFRSQGSLANKLTGETD-GEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLA 169
D SP S L G+ +N TD G D +T++ ++ +E+ G+KSL
Sbjct: 650 DASPTYSYCLLIEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSLE 709
Query: 170 PNRIVYCT 177
P R +CT
Sbjct: 710 PGRKSFCT 717
>D37781-1|BAA07035.1| 1337|Homo sapiens protein-tyrosine phosphatase
protein.
Length = 1337
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 111 DPSPRLSKQLCFRSQGSLANKLTGETD-GEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLA 169
D SP S L G+ +N TD G D +T++ ++ +E+ G+KSL
Sbjct: 650 DASPTYSYCLLIEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSLE 709
Query: 170 PNRIVYCT 177
P R +CT
Sbjct: 710 PGRKSFCT 717
>AF387844-1|AAM69432.1| 1305|Homo sapiens protein tyrosine
phosphatase receptor type J protein.
Length = 1305
Score = 35.1 bits (77), Expect = 1.4
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 111 DPSPRLSKQLCFRSQGSLANKLTGETD-GEVDTQLTKMDVVLTFQIEVVVMEVKGLKSLA 169
D SP S L G+ +N TD G D +T++ ++ +E+ G+KSL
Sbjct: 618 DASPTYSYCLLIEKAGNSSNATQVVTDIGITDATVTELIPGSSYTVEIFAQVGDGIKSLE 677
Query: 170 PNRIVYCT 177
P R +CT
Sbjct: 678 PGRKSFCT 685
>AY028805-1|AAK37776.1| 532|Homo sapiens leukocyte-derived arginine
aminopeptidase short form protein.
Length = 532
Score = 32.3 bits (70), Expect = 10.0
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 14/93 (15%)
Query: 951 GYVNFMRNSM--DQIRSKVTDELWIL-----QLFEQWYGNQVTM---INNWLSERPALHP 1000
G + + S+ D S +D+LW+ +L QW+GN VTM + WL+E A +
Sbjct: 340 GLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYM 399
Query: 1001 HQVACLSILLKKMYSDFEL----QGVIDDKLNS 1029
+A + + + D+ L + + D LNS
Sbjct: 400 ELIAVNATYPELQFDDYFLNVCFEVITKDSLNS 432
>AK074072-1|BAB84898.1| 373|Homo sapiens FLJ00143 protein protein.
Length = 373
Score = 32.3 bits (70), Expect = 10.0
Identities = 16/47 (34%), Positives = 29/47 (61%)
Query: 21 LLDSADEQAAAIRRELDGRMQKVNEMEKNRKLMPKFVLKEMESLYIE 67
LLD E +AA+R+E+D +KV E E+ + + + + +E E L ++
Sbjct: 54 LLDGEMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQ 100
>AB163917-1|BAD90015.1| 532|Homo sapiens leukocyte-derived arginine
aminopeptidase short form variant 2 protein.
Length = 532
Score = 32.3 bits (70), Expect = 10.0
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 14/93 (15%)
Query: 951 GYVNFMRNSM--DQIRSKVTDELWIL-----QLFEQWYGNQVTM---INNWLSERPALHP 1000
G + + S+ D S +D+LW+ +L QW+GN VTM + WL+E A +
Sbjct: 340 GLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYM 399
Query: 1001 HQVACLSILLKKMYSDFEL----QGVIDDKLNS 1029
+A + + + D+ L + + D LNS
Sbjct: 400 ELIAVNATYPELQFDDYFLNVCFEVITKDSLNS 432
>AB109031-1|BAC78818.1| 960|Homo sapiens leukocyte-derived arginine
aminopeptidase long form variant protein.
Length = 960
Score = 32.3 bits (70), Expect = 10.0
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 14/93 (15%)
Query: 951 GYVNFMRNSM--DQIRSKVTDELWIL-----QLFEQWYGNQVTM---INNWLSERPALHP 1000
G + + S+ D S +D+LW+ +L QW+GN VTM + WL+E A +
Sbjct: 340 GLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLNEGFAKYM 399
Query: 1001 HQVACLSILLKKMYSDFEL----QGVIDDKLNS 1029
+A + + + D+ L + + D LNS
Sbjct: 400 ELIAVNATYPELQFDDYFLNVCFEVITKDSLNS 432
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.400
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 160,440,704
Number of Sequences: 224733
Number of extensions: 6905143
Number of successful extensions: 14360
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 14215
Number of HSP's gapped (non-prelim): 73
length of query: 1115
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1017
effective length of database: 51,211,004
effective search space: 52081591068
effective search space used: 52081591068
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 70 (32.3 bits)
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