Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA003802-TA|BGIBMGA003802-PA|IPR000719|Protein kinase,
IPR008266|Tyrosine protein kinase, active site, IPR001245|Tyrosine
protein kinase, IPR011009|Protein kinase-like
(892 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein. 151 1e-35
X15786-1|CAA33787.1| 899|Homo sapiens retII protein. 151 1e-35
X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret proto... 151 1e-35
DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protei... 151 1e-35
M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA ... 151 1e-35
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 151 1e-35
BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene prot... 151 1e-35
M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary... 150 2e-35
AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase rec... 146 2e-34
M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein. 146 3e-34
Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus o... 145 5e-34
Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus o... 145 5e-34
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 145 5e-34
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 145 5e-34
M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3 (rea... 145 5e-34
M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein. 145 5e-34
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 145 5e-34
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 145 5e-34
AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus... 145 5e-34
AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus... 145 5e-34
AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor varian... 145 5e-34
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 143 3e-33
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 143 3e-33
X52213-1|CAA36460.1| 464|Homo sapiens ltk protein. 142 7e-33
X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein. 141 9e-33
D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase... 141 9e-33
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 138 6e-32
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 138 6e-32
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 138 6e-32
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 138 6e-32
M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase p... 133 2e-30
BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein. 133 2e-30
AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein. 133 2e-30
Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase ... 130 2e-29
X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine k... 130 2e-29
L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase p... 130 2e-29
L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine... 130 2e-29
BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein. 130 2e-29
AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinas... 130 2e-29
AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein. 130 2e-29
AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5 i... 130 2e-29
U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinas... 129 4e-29
U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinas... 129 4e-29
U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic ... 129 4e-29
D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein. 129 4e-29
AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplast... 129 4e-29
AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplast... 129 4e-29
AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplast... 129 4e-29
AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein. 129 4e-29
AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kin... 129 4e-29
BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein. 129 5e-29
X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyros... 128 7e-29
U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase ... 128 7e-29
U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinem... 128 7e-29
U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia... 128 7e-29
M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine ... 128 7e-29
L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia... 128 7e-29
BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinem... 128 7e-29
BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinem... 128 7e-29
AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinem... 128 7e-29
AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyros... 128 9e-29
BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein pr... 127 2e-28
M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase p... 126 3e-28
BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein. 126 3e-28
AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3 c... 126 3e-28
AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyros... 126 3e-28
U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein. 126 5e-28
L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine... 125 8e-28
L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein. 125 8e-28
X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein. 124 2e-27
AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes va... 124 2e-27
AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes va... 124 2e-27
AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes va... 124 2e-27
X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein. 123 2e-27
BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene... 123 2e-27
L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine... 123 3e-27
BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein. 123 3e-27
BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein. 123 3e-27
AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein. 123 3e-27
AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein. 123 3e-27
AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein. 123 3e-27
AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7 v... 123 3e-27
L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase p... 122 4e-27
D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine k... 122 4e-27
D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor... 122 4e-27
AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein. 122 4e-27
AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein. 122 4e-27
AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase... 122 4e-27
AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein p... 122 4e-27
X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein. 122 6e-27
M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine ... 122 6e-27
M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk proto... 122 6e-27
DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine le... 122 6e-27
BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein pr... 122 6e-27
BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein. 122 6e-27
BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein. 122 6e-27
AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine le... 122 6e-27
AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine le... 122 6e-27
AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine le... 122 6e-27
AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine le... 122 6e-27
AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine k... 122 6e-27
AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine le... 122 6e-27
AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine le... 122 6e-27
AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein. 122 6e-27
X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein pr... 122 7e-27
X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of t... 121 1e-26
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 121 1e-26
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 121 1e-26
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 121 1e-26
AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens ... 121 1e-26
AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine k... 121 1e-26
AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine k... 121 1e-26
Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein. 121 1e-26
X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor ... 121 1e-26
X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA ... 121 1e-26
M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor ... 121 1e-26
M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor ... 121 1e-26
M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor ... 121 1e-26
M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth facto... 121 1e-26
M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein. 121 1e-26
M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human heparin-b... 121 1e-26
J03358-1|AAA61190.1| 822|Homo sapiens FER protein. 121 1e-26
DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth facto... 121 1e-26
BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein. 121 1e-26
AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth facto... 121 1e-26
AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth fac... 121 1e-26
AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth fac... 121 1e-26
AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth fac... 121 1e-26
AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth fac... 121 1e-26
AF125808-1|AAF19762.1| 318|Homo sapiens ETS related protein-neu... 121 1e-26
AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth facto... 121 1e-26
AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth recep... 121 1e-26
AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-gro... 121 1e-26
AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein. 121 1e-26
AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein. 121 1e-26
AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein. 121 1e-26
AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein. 121 1e-26
AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein. 121 1e-26
AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein. 121 1e-26
AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein. 121 1e-26
Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase p... 120 2e-26
X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase pr... 120 2e-26
U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein. 120 2e-26
L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase p... 120 2e-26
BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein. 120 2e-26
BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase ... 120 2e-26
BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase ... 120 2e-26
AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase ... 120 2e-26
AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase ... 120 2e-26
X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase ... 120 2e-26
M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein. 120 2e-26
M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor ... 120 2e-26
BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein. 120 2e-26
BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein. 120 2e-26
BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with im... 120 2e-26
AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth facto... 120 2e-26
AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with i... 120 2e-26
AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with im... 120 2e-26
AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth facto... 120 2e-26
AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth facto... 120 2e-26
AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth facto... 120 2e-26
AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein. 120 2e-26
X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for ... 119 5e-26
BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR) associ... 118 7e-26
BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein. 118 7e-26
AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative kinas... 118 7e-26
AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein. 118 7e-26
AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase pr... 118 7e-26
L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine... 118 9e-26
BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4 p... 118 9e-26
BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein. 118 9e-26
BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein. 118 9e-26
AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein. 118 9e-26
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 117 2e-25
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 117 2e-25
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 117 2e-25
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 117 2e-25
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 117 2e-25
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 117 2e-25
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 117 2e-25
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 117 2e-25
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 117 2e-25
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 117 2e-25
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 117 2e-25
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 117 2e-25
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 117 2e-25
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 117 2e-25
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 117 2e-25
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 117 2e-25
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 117 2e-25
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 117 2e-25
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 117 2e-25
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 117 2e-25
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 117 2e-25
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 117 2e-25
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 117 2e-25
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 117 2e-25
S76475-1|AAB33111.1| 839|Homo sapiens trkC protein. 116 4e-25
AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein. 116 4e-25
U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein pr... 116 5e-25
U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene pr... 116 5e-25
M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein. 116 5e-25
BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene (hep... 116 5e-25
AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene prec... 116 5e-25
Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein. 115 6e-25
X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor ... 115 6e-25
X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor ... 115 6e-25
X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor ... 115 6e-25
X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor ... 115 6e-25
X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor ... 115 6e-25
X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA ... 115 6e-25
X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for ... 115 6e-25
U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor ... 115 6e-25
S76473-1|AAB33109.1| 822|Homo sapiens trkB protein. 115 6e-25
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 115 6e-25
M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor ... 115 6e-25
M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth f... 115 6e-25
M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblas... 115 6e-25
M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblas... 115 6e-25
M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblas... 115 6e-25
BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth facto... 115 6e-25
BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth facto... 115 6e-25
BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein. 115 6e-25
AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth facto... 115 6e-25
AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine k... 115 6e-25
AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine k... 115 6e-25
AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine k... 115 6e-25
AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine k... 115 6e-25
AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine k... 115 6e-25
AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine k... 115 6e-25
AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens ... 115 6e-25
AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor ... 115 6e-25
AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor t... 115 6e-25
AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine k... 115 6e-25
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 115 6e-25
AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth facto... 115 6e-25
J02958-1|AAA59591.1| 1408|Homo sapiens MET protein. 115 9e-25
X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein. 114 1e-24
BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine ki... 114 1e-24
BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine ki... 114 1e-24
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 114 1e-24
BC128386-1|AAI28387.1| 940|Homo sapiens ROR1 protein protein. 114 1e-24
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 114 1e-24
BC035514-1|AAH35514.2| 1124|Homo sapiens TEK tyrosine kinase, en... 114 1e-24
AL445205-2|CAH71706.1| 937|Homo sapiens receptor tyrosine kinas... 114 1e-24
AL161742-2|CAI21932.1| 937|Homo sapiens receptor tyrosine kinas... 114 1e-24
AL137859-2|CAI21732.1| 937|Homo sapiens receptor tyrosine kinas... 114 1e-24
AB209697-1|BAD92934.1| 892|Homo sapiens v-erb-a erythroblastic ... 114 1e-24
L06139-1|AAA61139.1| 1124|Homo sapiens receptor protein-tyrosine... 113 2e-24
D29767-1|BAA06171.1| 631|Homo sapiens Tec protein-tyrosine kina... 113 2e-24
BC032413-1|AAH32413.1| 505|Homo sapiens B lymphoid tyrosine kin... 113 2e-24
BC007371-1|AAH07371.1| 505|Homo sapiens B lymphoid tyrosine kin... 113 2e-24
AL133411-1|CAI16055.1| 1124|Homo sapiens TEK tyrosine kinase, en... 113 2e-24
AB208796-1|BAD92033.1| 1157|Homo sapiens TEK tyrosine kinase var... 113 2e-24
BC018703-1|AAH18703.1| 599|Homo sapiens Unknown (protein for IM... 113 3e-24
Z33998-1|CAA83965.1| 505|Homo sapiens Protein-Tyrosine Kinase p... 113 3e-24
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 113 3e-24
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 113 3e-24
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 113 3e-24
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 113 3e-24
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 113 3e-24
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 113 3e-24
AF359246-1|AAK51435.1| 592|Homo sapiens fibroblast growth facto... 113 3e-24
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 113 3e-24
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 113 3e-24
S76617-1|AAB33265.1| 505|Homo sapiens blk protein. 112 5e-24
AL035703-1|CAB81612.1| 1005|Homo sapiens EPH receptor A8 protein. 112 6e-24
AK222718-1|BAD96438.1| 820|Homo sapiens fibroblast growth facto... 112 6e-24
AB067470-1|BAB67776.1| 1480|Homo sapiens KIAA1883 protein protein. 112 6e-24
AB040892-1|BAA95983.1| 853|Homo sapiens KIAA1459 protein protein. 112 6e-24
M97675-1|AAA60275.1| 937|Homo sapiens transmembrane receptor pr... 111 8e-24
AL157486-1|CAB75674.1| 364|Homo sapiens hypothetical protein pr... 111 8e-24
M15990-1|AAA35735.1| 543|Homo sapiens protein ( Human c-yes-1 m... 111 1e-23
BC048960-1|AAH48960.1| 543|Homo sapiens v-yes-1 Yamaguchi sarco... 111 1e-23
Z97989-4|CAI22300.1| 537|Homo sapiens FYN oncogene related to S... 110 2e-23
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 110 2e-23
U07236-1|AAA18225.1| 512|Homo sapiens lymphocyte-specific prote... 110 2e-23
M14333-1|AAC08285.1| 537|Homo sapiens protein ( Homo sapiens c-... 110 2e-23
BC112933-1|AAI12934.1| 387|Homo sapiens Unknown (protein for MG... 110 2e-23
X00588-1|CAA25240.1| 1210|Homo sapiens epidermal growth factor r... 109 3e-23
BC094761-1|AAH94761.1| 1091|Homo sapiens EGFR protein protein. 109 3e-23
AY588246-1|AAS83109.1| 1210|Homo sapiens epidermal growth factor... 109 3e-23
AY550966-1|AAT52212.1| 1210|Homo sapiens cell growth inhibiting ... 109 3e-23
AF288738-1|AAG35789.1| 1210|Homo sapiens p170 epidermal growth f... 109 3e-23
AB209442-1|BAD92679.1| 1081|Homo sapiens epidermal growth factor... 109 3e-23
X58741-1|CAA41565.2| 348|Homo sapiens tyrosine kinase protein. 109 4e-23
M16592-1|AAA52644.1| 505|Homo sapiens HCK protein. 109 4e-23
M16591-1|AAA52643.1| 505|Homo sapiens HCK protein. 109 4e-23
M14676-1|AAA36615.1| 537|Homo sapiens protein ( Human src-like ... 109 4e-23
BC114463-1|AAI14464.2| 526|Homo sapiens hemopoietic cell kinase... 109 4e-23
BC108931-1|AAI08932.2| 526|Homo sapiens hemopoietic cell kinase... 109 4e-23
BC108930-1|AAI08931.2| 526|Homo sapiens hemopoietic cell kinase... 109 4e-23
BC094847-1|AAH94847.2| 526|Homo sapiens hemopoietic cell kinase... 109 4e-23
BC014435-1|AAH14435.2| 526|Homo sapiens hemopoietic cell kinase... 109 4e-23
AL353092-2|CAI19694.1| 505|Homo sapiens hemopoietic cell kinase... 109 4e-23
AL353092-1|CAI19695.1| 504|Homo sapiens hemopoietic cell kinase... 109 4e-23
AL049539-2|CAI22967.1| 504|Homo sapiens hemopoietic cell kinase... 109 4e-23
AL049539-1|CAI22966.1| 505|Homo sapiens hemopoietic cell kinase... 109 4e-23
AK026432-1|BAB15482.1| 505|Homo sapiens protein ( Homo sapiens ... 109 4e-23
M79321-1|AAB50019.1| 491|Homo sapiens Lyn B protein protein. 108 7e-23
M16038-1|AAA59540.1| 512|Homo sapiens LYN protein. 108 7e-23
BC126458-1|AAI26459.1| 512|Homo sapiens LYN protein protein. 108 7e-23
BC126456-1|AAI26457.1| 512|Homo sapiens LYN protein protein. 108 7e-23
BC075002-1|AAH75002.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 108 7e-23
BC075001-1|AAH75001.1| 512|Homo sapiens v-yes-1 Yamaguchi sarco... 108 7e-23
BC068551-1|AAH68551.1| 582|Homo sapiens LYN protein protein. 108 7e-23
BC059394-1|AAH59394.1| 582|Homo sapiens LYN protein protein. 108 7e-23
X74764-1|CAA52777.1| 855|Homo sapiens protein-tyrosine kinase p... 108 1e-22
U22322-1|AAC50116.1| 505|Homo sapiens Rak protein. 108 1e-22
U07695-1|AAA20598.1| 987|Homo sapiens tyrosine kinase protein. 108 1e-22
U00803-1|AAA18284.1| 505|Homo sapiens SRC-like tyrosine kinase ... 108 1e-22
D14717-1|BAA03537.1| 347|Homo sapiens large erk kinase protein. 108 1e-22
BC113854-1|AAI13855.2| 504|Homo sapiens HCK protein protein. 108 1e-22
BC052998-1|AAH52998.1| 855|Homo sapiens discoidin domain recept... 108 1e-22
BC052804-1|AAH52804.1| 987|Homo sapiens EPH receptor B4 protein. 108 1e-22
BC012916-1|AAH12916.1| 505|Homo sapiens fyn-related kinase prot... 108 1e-22
BC004264-1|AAH04264.1| 845|Homo sapiens EPHB4 protein protein. 108 1e-22
AY056048-1|AAL14195.1| 935|Homo sapiens receptor protein tyrosi... 108 1e-22
AY056047-1|AAL14194.1| 987|Homo sapiens receptor protein tyrosi... 108 1e-22
AL445197-3|CAI15941.1| 855|Homo sapiens discoidin domain recept... 108 1e-22
AL357141-2|CAI16469.1| 505|Homo sapiens fyn-related kinase prot... 108 1e-22
AL121963-8|CAB87592.2| 505|Homo sapiens fyn-related kinase prot... 108 1e-22
AF312032-8|AAK21010.1| 987|Homo sapiens ephrin type-B receptor ... 108 1e-22
AB209644-1|BAD92881.1| 986|Homo sapiens ephrin receptor EphB4 p... 108 1e-22
X96588-1|CAA65406.1| 577|Homo sapiens receptor tyrosine kinase ... 107 1e-22
X83107-1|CAA58169.1| 675|Homo sapiens bmx protein. 107 1e-22
X69970-1|CAA49591.1| 607|Homo sapiens h-ryk protein. 107 1e-22
X14055-1|CAA32211.1| 509|Homo sapiens protein ( Human lymphocyt... 107 1e-22
X13529-1|CAA31884.1| 509|Homo sapiens protein ( Human lck mRNA ... 107 1e-22
BC021700-1|AAH21700.2| 395|Homo sapiens RYK protein protein. 107 1e-22
BC016652-1|AAH16652.1| 675|Homo sapiens BMX non-receptor tyrosi... 107 1e-22
AL121991-2|CAI22320.1| 496|Homo sapiens lymphocyte-specific pro... 107 1e-22
AF228313-1|AAF34794.1| 496|Homo sapiens tyrosine kinase LCK pro... 107 1e-22
AF045459-1|AAC08966.1| 697|Homo sapiens Etk/Bmx cytosolic tyros... 107 1e-22
M97639-1|AAA60276.1| 943|Homo sapiens transmembrane receptor pr... 107 2e-22
BC130522-1|AAI30523.1| 943|Homo sapiens receptor tyrosine kinas... 107 2e-22
AL928802-2|CAI17303.1| 943|Homo sapiens receptor tyrosine kinas... 107 2e-22
AL928802-1|CAI17302.1| 704|Homo sapiens receptor tyrosine kinas... 107 2e-22
AL591214-1|CAH71099.1| 704|Homo sapiens receptor tyrosine kinas... 107 2e-22
AL583841-2|CAI15694.1| 943|Homo sapiens receptor tyrosine kinas... 107 2e-22
AL583841-1|CAI15693.1| 704|Homo sapiens receptor tyrosine kinas... 107 2e-22
AL391219-1|CAH70208.1| 943|Homo sapiens receptor tyrosine kinas... 107 2e-22
AF294796-1|AAG01184.2| 910|Homo sapiens ROR2 protein protein. 107 2e-22
AB209154-1|BAD92391.1| 919|Homo sapiens Tyrosine-protein kinase... 107 2e-22
Z97989-6|CAI22299.1| 485|Homo sapiens FYN oncogene related to S... 106 3e-22
Z97989-5|CAI22301.1| 534|Homo sapiens FYN oncogene related to S... 106 3e-22
X77278-1|CAA54493.1| 507|Homo sapiens HYL tyrosine kinase protein. 106 3e-22
S75164-1|AAC60645.1| 507|Homo sapiens megakaryocyte-associated ... 106 3e-22
BC003109-1|AAH03109.1| 507|Homo sapiens megakaryocyte-associate... 106 3e-22
BC000114-1|AAH00114.1| 507|Homo sapiens megakaryocyte-associate... 106 3e-22
AC005777-1|AAC62843.1| 507|Homo sapiens MATK_HUMAN protein. 106 3e-22
X02647-1|CAA26485.1| 351|Homo sapiens c-src protein. 106 4e-22
K03218-1|AAA60584.1| 536|Homo sapiens SRC protein. 106 4e-22
BC051270-1|AAH51270.2| 536|Homo sapiens v-src sarcoma (Schmidt-... 106 4e-22
BC013200-1|AAH13200.1| 539|Homo sapiens LCK protein protein. 106 4e-22
BC011566-1|AAH11566.1| 536|Homo sapiens SRC protein protein. 106 4e-22
AL133293-2|CAC10573.1| 542|Homo sapiens v-src sarcoma (Schmidt-... 106 4e-22
AL133293-1|CAC34523.1| 536|Homo sapiens v-src sarcoma (Schmidt-... 106 4e-22
AL121991-3|CAI22321.1| 526|Homo sapiens lymphocyte-specific pro... 106 4e-22
S74774-1|AAB33113.2| 534|Homo sapiens tyrosine kinase p59fyn(T)... 105 5e-22
M36881-1|AAA59502.1| 509|Homo sapiens lymphocyte-specific prote... 105 7e-22
BC070070-1|AAH70070.1| 876|Homo sapiens DDR1 protein protein. 105 9e-22
Z29093-1|CAA82335.1| 876|Homo sapiens receptor tyrosine kinase ... 104 1e-21
X74979-1|CAA52915.1| 876|Homo sapiens TrkE protein. 104 1e-21
L57508-1|AAB05208.1| 876|Homo sapiens receptor kinase protein. 104 1e-21
L20817-1|AAA18019.1| 913|Homo sapiens tyrosine protein kinase p... 104 1e-21
BC013400-1|AAH13400.1| 876|Homo sapiens discoidin domain recept... 104 1e-21
BC008716-1|AAH08716.1| 876|Homo sapiens discoidin domain recept... 104 1e-21
BA000025-66|BAB63318.1| 913|Homo sapiens Receptor tyrosine kina... 104 1e-21
AL773589-2|CAI18534.1| 876|Homo sapiens discoidin domain recept... 104 1e-21
AL773589-1|CAI18533.1| 913|Homo sapiens discoidin domain recept... 104 1e-21
AL773541-2|CAI18450.1| 876|Homo sapiens discoidin domain recept... 104 1e-21
AL773541-1|CAI18451.1| 913|Homo sapiens discoidin domain recept... 104 1e-21
AL662870-7|CAI18442.1| 913|Homo sapiens discoidin domain recept... 104 1e-21
AL662870-6|CAI18441.1| 876|Homo sapiens discoidin domain recept... 104 1e-21
AL662854-7|CAI17433.1| 913|Homo sapiens discoidin domain recept... 104 1e-21
AL662854-6|CAI17434.1| 876|Homo sapiens discoidin domain recept... 104 1e-21
AB210021-1|BAE06103.1| 894|Homo sapiens DDR1 variant protein pr... 104 1e-21
AB202100-1|BAE78621.1| 876|Homo sapiens discoidin domain recept... 104 1e-21
AB103608-1|BAF31270.1| 913|Homo sapiens DDR protein protein. 104 1e-21
AB088102-1|BAC54935.1| 913|Homo sapiens receptor tyrosine kinas... 104 1e-21
U48705-1|AAC50917.1| 913|Homo sapiens tyrosine kinase DDR protein. 104 2e-21
L11315-1|AAA02866.1| 913|Homo sapiens receptor tyrosine kinase ... 104 2e-21
BC032496-1|AAH32496.1| 482|Homo sapiens FYN oncogene related to... 103 4e-21
X05027-1|CAA28691.1| 507|Homo sapiens protein ( Human T cell-sp... 102 5e-21
M76125-1|AAA61243.1| 885|Homo sapiens tyrosine kinase receptor ... 102 5e-21
M19722-1|AAA52451.1| 529|Homo sapiens FGR protein. 102 6e-21
BC064382-1|AAH64382.1| 529|Homo sapiens Gardner-Rasheed feline ... 102 6e-21
BC032229-1|AAH32229.1| 894|Homo sapiens AXL receptor tyrosine k... 102 6e-21
AL031729-3|CAB62998.1| 529|Homo sapiens Gardner-Rasheed feline ... 102 6e-21
X98208-1|CAA66871.1| 913|Homo sapiens discoidin receptor tyrosi... 101 1e-20
S71669-1|AAB30995.1| 465|Homo sapiens lsk protein. 101 1e-20
X57019-1|CAA40338.1| 894|Homo sapiens protein ( H.sapiens mRNA ... 101 1e-20
S65125-1|AAB20305.1| 894|Homo sapiens UFO protein. 101 1e-20
AK024281-1|BAB14871.1| 251|Homo sapiens protein ( Homo sapiens ... 101 1e-20
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 100 2e-20
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 100 2e-20
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 100 2e-20
AJ865079-1|CAI23831.1| 516|Homo sapiens proto-oncogene tyrosine... 100 2e-20
L18974-1|AAA16703.1| 527|Homo sapiens tyrosine kinase protein. 100 5e-20
X70040-1|CAA49634.1| 1400|Homo sapiens tyrosine kinase protein. 99 6e-20
S59184-1|AAB26341.1| 606|Homo sapiens RYK protein. 99 6e-20
AY513655-1|AAS82867.1| 681|Homo sapiens proto-oncogene c-fes va... 98 1e-19
AL662870-9|CAM25688.1| 377|Homo sapiens discoidin domain recept... 97 3e-19
AL662854-9|CAM24839.1| 377|Homo sapiens discoidin domain recept... 97 3e-19
L05186-1|AAA35819.1| 879|Homo sapiens focal adhesion kinase pro... 94 2e-18
BC008655-1|AAH08655.1| 253|Homo sapiens EPHA2 protein protein. 93 3e-18
BC039695-1|AAH39695.1| 1129|Homo sapiens JAK2 protein protein. 93 5e-18
AY973034-1|AAY22962.1| 1132|Homo sapiens Janus kinase 2 protein. 93 5e-18
AL161450-1|CAD13329.1| 1132|Homo sapiens Janus kinase 2 (a prote... 93 5e-18
AF058925-1|AAC23982.1| 1132|Homo sapiens Jak2 kinase protein. 93 5e-18
AF005216-1|AAB82092.1| 1132|Homo sapiens receptor-associated tyr... 93 5e-18
AF001362-1|AAC23653.1| 1132|Homo sapiens Jak2 kinase protein. 93 5e-18
D83492-1|BAA21560.1| 1006|Homo sapiens Eph-family protein protein. 92 9e-18
BC110607-1|AAI10608.2| 1006|Homo sapiens EPH receptor B6 protein. 92 9e-18
BC110606-1|AAI10607.1| 729|Homo sapiens EPHB6 protein protein. 92 9e-18
AY280502-1|AAP20939.1| 1006|Homo sapiens EPHB6 protein. 92 9e-18
U70065-1|AAC50950.1| 1124|Homo sapiens JAK3 protein. 91 1e-17
M14209-1|AAA52441.1| 211|Homo sapiens fes/fps proto-oncogene pr... 90 3e-17
X74765-1|CAB58562.1| 450|Homo sapiens protein tyrosine kinase p... 90 4e-17
X60114-1|CAA42713.1| 450|Homo sapiens put. cytoplasmic tyrosine... 90 4e-17
X59932-1|CAA42556.1| 450|Homo sapiens c-src-kinase protein. 90 4e-17
U09607-1|AAA19626.1| 1124|Homo sapiens JAK family protein tyrosi... 90 4e-17
DQ075211-1|AAY57329.1| 450|Homo sapiens c-src tyrosine kinase p... 90 4e-17
CR541960-1|CAG46758.1| 450|Homo sapiens CSK protein. 90 4e-17
BC106073-1|AAI06074.1| 450|Homo sapiens c-src tyrosine kinase p... 90 4e-17
BC104875-1|AAI04876.1| 450|Homo sapiens c-src tyrosine kinase p... 90 4e-17
BC104847-1|AAI04848.1| 450|Homo sapiens c-src tyrosine kinase p... 90 4e-17
M11767-1|AAA35808.1| 295|Homo sapiens protooncogene protein pro... 89 6e-17
S65186-1|AAB28072.2| 620|Homo sapiens EMT protein. 89 9e-17
L10717-1|AAA36748.1| 620|Homo sapiens tyrosine kinase protein. 89 9e-17
D13720-1|BAA02873.1| 620|Homo sapiens ITK protein. 89 9e-17
BC109078-1|AAI09079.1| 620|Homo sapiens IL2-inducible T-cell ki... 89 9e-17
BC109077-1|AAI09078.1| 620|Homo sapiens IL2-inducible T-cell ki... 89 9e-17
X75208-1|CAA53021.1| 998|Homo sapiens protein tyrosine kinase-r... 88 1e-16
BC052968-1|AAH52968.1| 998|Homo sapiens EPH receptor B3 protein. 88 1e-16
BC035782-1|AAH35782.1| 661|Homo sapiens TNK1 protein protein. 88 1e-16
AF097738-1|AAC99412.1| 661|Homo sapiens non-receptor tyosine ki... 88 1e-16
X54637-1|CAA38449.1| 1187|Homo sapiens protein ( Human tyk2 mRNA... 88 1e-16
U31601-1|AAC50226.1| 1094|Homo sapiens JAK3B protein. 88 1e-16
BC093824-1|AAH93824.1| 422|Homo sapiens serine/threonine/tyrosi... 88 1e-16
BC093822-1|AAH93822.1| 422|Homo sapiens serine/threonine/tyrosi... 88 1e-16
BC014243-1|AAH14243.1| 1187|Homo sapiens tyrosine kinase 2 protein. 88 1e-16
AY549314-1|AAS37680.1| 1187|Homo sapiens tyrosine kinase 2 protein. 88 1e-16
AF513860-1|AAM44860.1| 1124|Homo sapiens Janus kinase 3 (a prote... 88 1e-16
AC007201-2|AAD22741.1| 1124|Homo sapiens JAK3_HUMAN protein. 88 1e-16
AY563054-1|AAT01226.1| 422|Homo sapiens tyrosine kinase protein... 87 2e-16
AK223626-1|BAD97346.1| 449|Homo sapiens c-src tyrosine kinase v... 87 2e-16
U43408-1|AAC50427.1| 666|Homo sapiens tyrosine kinase protein. 87 3e-16
AM051280-1|CAJ19686.1| 208|Homo sapiens dominant-negative kinas... 87 3e-16
AF251059-1|AAK34949.1| 422|Homo sapiens kinase domain protein p... 87 3e-16
AF153764-1|AAF37341.1| 172|Homo sapiens Bruton's tyrosine kinas... 87 3e-16
AF153758-1|AAF37335.1| 174|Homo sapiens Bruton's tyrosine kinas... 87 3e-16
AF153757-1|AAF37334.1| 174|Homo sapiens Bruton's tyrosine kinas... 87 3e-16
AF153756-1|AAF37333.1| 174|Homo sapiens Bruton's tyrosine kinas... 87 3e-16
AF153762-1|AAF37339.1| 174|Homo sapiens Bruton's tyrosine kinas... 85 8e-16
AF037333-1|AAB94627.1| 943|Homo sapiens Eph-like receptor tyros... 85 8e-16
AF153760-1|AAF37337.1| 174|Homo sapiens Bruton's tyrosine kinas... 85 1e-15
AF153759-1|AAF37336.1| 174|Homo sapiens Bruton's tyrosine kinas... 85 1e-15
AF153761-1|AAF37338.1| 174|Homo sapiens Bruton's tyrosine kinas... 85 1e-15
AB209405-1|BAD92642.1| 232|Homo sapiens RYK receptor-like tyros... 85 1e-15
AL121829-14|CAC15526.1| 488|Homo sapiens protein ( Human DNA se... 82 1e-14
Z26652-1|CAA81393.1| 993|Homo sapiens FLT3 receptor tyrosine ki... 81 2e-14
U02687-1|AAA18947.1| 993|Homo sapiens serine/threonine protein ... 81 2e-14
BC126350-1|AAI26351.1| 993|Homo sapiens fms-related tyrosine ki... 81 2e-14
AF153364-1|AAF61477.1| 149|Homo sapiens Bruton's tyrosine kinas... 80 3e-14
L36162-1|AAA35487.1| 160|Homo sapiens receptor tyrosine kinase ... 80 4e-14
AL035422-4|CAI42359.1| 483|Homo sapiens Bruton agammaglobulinem... 79 7e-14
X06369-1|CAA29667.1| 142|Homo sapiens lck tyrosine kinase (AA 1... 79 9e-14
AL591024-3|CAH70634.1| 996|Homo sapiens fms-related tyrosine ki... 79 9e-14
AL445262-1|CAI17231.1| 996|Homo sapiens fms-related tyrosine ki... 79 9e-14
AL356915-1|CAI12447.1| 996|Homo sapiens fms-related tyrosine ki... 79 9e-14
X03663-1|CAA27300.1| 972|Homo sapiens protein ( Human mRNA for ... 77 2e-13
U63963-1|AAB51696.1| 972|Homo sapiens CSF-1 receptor protein. 77 2e-13
BC047521-1|AAH47521.1| 972|Homo sapiens colony stimulating fact... 77 2e-13
M22734-1|AAA60048.1| 1089|Homo sapiens platelet-derived growth f... 77 3e-13
M21574-1|AAA96715.1| 1089|Homo sapiens platelet-derived growth f... 77 3e-13
D50017-1|BAA08742.1| 1089|Homo sapiens alpha-platelet-derived gr... 77 3e-13
AY229892-1|AAP69563.1| 849|Homo sapiens FIP1L1/PDGFRA fusion pr... 77 3e-13
X78549-1|CAA55295.1| 451|Homo sapiens tyrosine kinase protein. 77 4e-13
U61412-1|AAC34935.1| 451|Homo sapiens non-receptor type protein... 77 4e-13
BC035843-1|AAH35843.1| 451|Homo sapiens PTK6 protein tyrosine k... 77 4e-13
AL121829-13|CAC15525.1| 451|Homo sapiens Ptk6 protein. 77 4e-13
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 75 8e-13
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 75 8e-13
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 75 8e-13
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 75 8e-13
AB209050-1|BAD92287.1| 551|Homo sapiens fms-related tyrosine ki... 75 8e-13
X04476-1|CAA28165.1| 135|Homo sapiens protein ( Human mRNA frag... 75 1e-12
U38894-1|AAC50714.1| 388|Homo sapiens tyrosine kinase t-Ror1 pr... 75 1e-12
AY233383-1|AAO89505.1| 1363|Homo sapiens VEGFR3 long form protein. 75 1e-12
>X56348-1|CAA39792.1| 435|Homo sapiens urf-ret protein.
Length = 435
Score = 151 bits (366), Expect = 1e-35
Identities = 97/309 (31%), Positives = 148/309 (47%), Gaps = 11/309 (3%)
Query: 580 HLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRKGAAPAEETEFLNEAVIMAAL 637
+LV LG G FG+V + G+A VAVK L++ A+P+E + L+E ++ +
Sbjct: 86 NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV 145
Query: 638 DHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH----FAEQSDHLSQDSKDFEE 693
+H H+I+ GAC GP L+++E+A +G LR +LRE R + + S D +
Sbjct: 146 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPD 205
Query: 694 SEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT 753
++ +VHRD+ A N LV R++K+ DFG++R D
Sbjct: 206 ERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSR--DVY 263
Query: 754 GADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSP 813
D Y R +G PV WMA ESL +++ SDVWS GVL+ E VTLG PY P
Sbjct: 264 EEDS---YVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 320
Query: 814 LRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
R+ + +G R E P CW++ +RP ++++ L R L
Sbjct: 321 ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 380
Query: 874 SRVAPDADS 882
+ +DS
Sbjct: 381 LAASTPSDS 389
>X15786-1|CAA33787.1| 899|Homo sapiens retII protein.
Length = 899
Score = 151 bits (366), Expect = 1e-35
Identities = 97/309 (31%), Positives = 148/309 (47%), Gaps = 11/309 (3%)
Query: 580 HLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRKGAAPAEETEFLNEAVIMAAL 637
+LV LG G FG+V + G+A VAVK L++ A+P+E + L+E ++ +
Sbjct: 508 NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV 567
Query: 638 DHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH----FAEQSDHLSQDSKDFEE 693
+H H+I+ GAC GP L+++E+A +G LR +LRE R + + S D +
Sbjct: 568 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPD 627
Query: 694 SEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT 753
++ +VHRD+ A N LV R++K+ DFG++R D
Sbjct: 628 ERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSR--DVY 685
Query: 754 GADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSP 813
D Y R +G PV WMA ESL +++ SDVWS GVL+ E VTLG PY P
Sbjct: 686 EEDS---YVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 742
Query: 814 LRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
R+ + +G R E P CW++ +RP ++++ L R L
Sbjct: 743 ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 802
Query: 874 SRVAPDADS 882
+ +DS
Sbjct: 803 LAASTPSDS 811
>X12949-1|CAA31408.1| 860|Homo sapiens protein ( Human ret
proto-oncogene mRNA for tyrosine kinase. ).
Length = 860
Score = 151 bits (366), Expect = 1e-35
Identities = 97/309 (31%), Positives = 148/309 (47%), Gaps = 11/309 (3%)
Query: 580 HLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRKGAAPAEETEFLNEAVIMAAL 637
+LV LG G FG+V + G+A VAVK L++ A+P+E + L+E ++ +
Sbjct: 469 NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV 528
Query: 638 DHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH----FAEQSDHLSQDSKDFEE 693
+H H+I+ GAC GP L+++E+A +G LR +LRE R + + S D +
Sbjct: 529 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPD 588
Query: 694 SEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT 753
++ +VHRD+ A N LV R++K+ DFG++R D
Sbjct: 589 ERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSR--DVY 646
Query: 754 GADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSP 813
D Y R +G PV WMA ESL +++ SDVWS GVL+ E VTLG PY P
Sbjct: 647 EEDS---YVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 703
Query: 814 LRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
R+ + +G R E P CW++ +RP ++++ L R L
Sbjct: 704 ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 763
Query: 874 SRVAPDADS 882
+ +DS
Sbjct: 764 LAASTPSDS 772
>DQ104207-1|AAZ57203.1| 776|Homo sapiens HOOK3-RET fusion protein
protein.
Length = 776
Score = 151 bits (366), Expect = 1e-35
Identities = 97/309 (31%), Positives = 148/309 (47%), Gaps = 11/309 (3%)
Query: 580 HLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRKGAAPAEETEFLNEAVIMAAL 637
+LV LG G FG+V + G+A VAVK L++ A+P+E + L+E ++ +
Sbjct: 385 NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV 444
Query: 638 DHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH----FAEQSDHLSQDSKDFEE 693
+H H+I+ GAC GP L+++E+A +G LR +LRE R + + S D +
Sbjct: 445 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPD 504
Query: 694 SEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT 753
++ +VHRD+ A N LV R++K+ DFG++R D
Sbjct: 505 ERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSR--DVY 562
Query: 754 GADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSP 813
D Y R +G PV WMA ESL +++ SDVWS GVL+ E VTLG PY P
Sbjct: 563 EEDS---YVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 619
Query: 814 LRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
R+ + +G R E P CW++ +RP ++++ L R L
Sbjct: 620 ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 679
Query: 874 SRVAPDADS 882
+ +DS
Sbjct: 680 LAASTPSDS 688
>M16029-1|AAA36786.1| 805|Homo sapiens protein ( Human ret mRNA
encoding a tyrosine kinase, partial cds. ).
Length = 805
Score = 151 bits (365), Expect = 1e-35
Identities = 97/309 (31%), Positives = 148/309 (47%), Gaps = 11/309 (3%)
Query: 580 HLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRKGAAPAEETEFLNEAVIMAAL 637
+LV LG G FG+V + G+A VAVK L++ A+P+E + L+E ++ +
Sbjct: 456 NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV 515
Query: 638 DHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH----FAEQSDHLSQDSKDFEE 693
+H H+I+ GAC GP L+++E+A +G LR +LRE R + + S D +
Sbjct: 516 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPD 575
Query: 694 SEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT 753
++ +VHRD+ A N LV R++K+ DFG++R D
Sbjct: 576 ERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSR--DVY 633
Query: 754 GADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSP 813
D Y R +G PV WMA ESL +++ SDVWS GVL+ E VTLG PY P
Sbjct: 634 EED---PYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 690
Query: 814 LRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
R+ + +G R E P CW++ +RP ++++ L R L
Sbjct: 691 ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 750
Query: 874 SRVAPDADS 882
+ +DS
Sbjct: 751 LAASTPSDS 759
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 151 bits (365), Expect = 1e-35
Identities = 97/309 (31%), Positives = 148/309 (47%), Gaps = 11/309 (3%)
Query: 580 HLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRKGAAPAEETEFLNEAVIMAAL 637
+LV LG G FG+V + G+A VAVK L++ A+P+E + L+E ++ +
Sbjct: 247 NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV 306
Query: 638 DHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH----FAEQSDHLSQDSKDFEE 693
+H H+I+ GAC GP L+++E+A +G LR +LRE R + + S D +
Sbjct: 307 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPD 366
Query: 694 SEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT 753
++ +VHRD+ A N LV R++K+ DFG++R D
Sbjct: 367 ERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSR--DVY 424
Query: 754 GADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSP 813
D Y R +G PV WMA ESL +++ SDVWS GVL+ E VTLG PY P
Sbjct: 425 EED---PYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 481
Query: 814 LRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
R+ + +G R E P CW++ +RP ++++ L R L
Sbjct: 482 ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 541
Query: 874 SRVAPDADS 882
+ +DS
Sbjct: 542 LAASTPSDS 550
>BC004257-1|AAH04257.1| 1072|Homo sapiens ret proto-oncogene protein.
Length = 1072
Score = 151 bits (365), Expect = 1e-35
Identities = 97/309 (31%), Positives = 148/309 (47%), Gaps = 11/309 (3%)
Query: 580 HLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRKGAAPAEETEFLNEAVIMAAL 637
+LV LG G FG+V + G+A VAVK L++ A+P+E + L+E ++ +
Sbjct: 723 NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV 782
Query: 638 DHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH----FAEQSDHLSQDSKDFEE 693
+H H+I+ GAC GP L+++E+A +G LR +LRE R + + S D +
Sbjct: 783 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPD 842
Query: 694 SEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT 753
++ +VHRD+ A N LV R++K+ DFG++R D
Sbjct: 843 ERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSR--DVY 900
Query: 754 GADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSP 813
D Y R +G PV WMA ESL +++ SDVWS GVL+ E VTLG PY P
Sbjct: 901 EEDS---YVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 957
Query: 814 LRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
R+ + +G R E P CW++ +RP ++++ L R L
Sbjct: 958 ERLFNLLKTGHRMERPDNCSEEMYCLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 1017
Query: 874 SRVAPDADS 882
+ +DS
Sbjct: 1018 LAASTPSDS 1026
>M31213-1|AAA36524.1| 503|Homo sapiens protein ( Human papillary
thyroid carcinoma-encoded protein mRNA, complete cds. ).
Length = 503
Score = 150 bits (364), Expect = 2e-35
Identities = 100/329 (30%), Positives = 154/329 (46%), Gaps = 11/329 (3%)
Query: 560 RPAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRK 617
R + VT E ++ +LV LG G FG+V + G+ VAVK L++
Sbjct: 92 RDLRKASVTIEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRGGYTTVAVKMLKE 151
Query: 618 GAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH- 676
A+P+E + L+E ++ ++H H+I+ GAC GP L+++E+A +G LR +LRE R
Sbjct: 152 NASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKV 211
Query: 677 ---FAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLV 733
+ + S D + ++ +VHRD+ A N LV
Sbjct: 212 GPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILV 271
Query: 734 DSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSL 793
R++K+ DFG++R D D Y R +G PV WMA ESL +++ SDVWS
Sbjct: 272 AEGRKMKISDFGLSR--DVYEEDS---YVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSF 326
Query: 794 GVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPA 853
GVL+ E VTLG PY P R+ + +G R E P CW++ +RP
Sbjct: 327 GVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPV 386
Query: 854 AGEVARYLRDHPRALRPVLRSRVAPDADS 882
++++ L R L + +DS
Sbjct: 387 FADISKDLEKMMVKRRDYLDLAASTPSDS 415
>AJ243297-1|CAB46483.1| 1091|Homo sapiens RET tyrosine kinase receptor
protein.
Length = 1091
Score = 147 bits (355), Expect = 2e-34
Identities = 95/309 (30%), Positives = 148/309 (47%), Gaps = 10/309 (3%)
Query: 580 HLVTYDILGTGRFGRV-HLGVLQVPGKAP-RPVAVKSLRKGAAPAEETEFLNEAVIMAAL 637
+LV LG G FG+V + G+A VAVK L++ A+P+E + L+E ++ +
Sbjct: 699 NLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQV 758
Query: 638 DHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRH----FAEQSDHLSQDSKDFEE 693
+H H+I+ GAC GP L+++E+A +G LR +LRE R + + S D +
Sbjct: 759 NHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPD 818
Query: 694 SEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT 753
++ +VHRD+ A N LV R++K+ DFG++R D
Sbjct: 819 ERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSR--DVY 876
Query: 754 GADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSP 813
D + + + G PV WMA ESL +++ SDVWS GVL+ E VTLG PY P
Sbjct: 877 EEDSYVKRS--QVGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP 934
Query: 814 LRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
R+ + +G R E P CW++ +RP ++++ L R L
Sbjct: 935 ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 994
Query: 874 SRVAPDADS 882
+ +DS
Sbjct: 995 LAASTPSDS 1003
>M34353-1|AAA60278.1| 2347|Homo sapiens ROS1 protein.
Length = 2347
Score = 146 bits (354), Expect = 3e-34
Identities = 107/308 (34%), Positives = 149/308 (48%), Gaps = 31/308 (10%)
Query: 566 PVTQELTRFLVDPAHLVTYDIL-GTGRFGRVHLG----VLQVPGKAPRPVAVKSLRKGAA 620
P +E+ P +T +L G+G FG V+ G +L V G VAVK+L+KG+
Sbjct: 1929 PTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGV-GSGEIKVAVKTLKKGST 1987
Query: 621 PAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQ 680
E+ EFL EA +M+ +H +I++ +G C+ P +++E GDL YLR+ R
Sbjct: 1988 DQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFY 2047
Query: 681 SDHLSQ-DSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVD----- 734
L+ D D R +HRD+ A NCLV
Sbjct: 2048 GPLLTLVDLVDL--------------CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYT 2093
Query: 735 SRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
S R +K+GDFG+AR D D Y R GL PV WMAPESL G F++ SDVWS G
Sbjct: 2094 SPRIVKIGDFGLAR--DIYKND---YYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG 2148
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAA 854
+L+ E +TLG +PY + S L VL +V +GGR E P CW + +RP
Sbjct: 2149 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTF 2208
Query: 855 GEVARYLR 862
+ L+
Sbjct: 2209 HRIQNQLQ 2216
>Z98880-3|CAI42375.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 145 bits (352), Expect = 5e-34
Identities = 106/298 (35%), Positives = 146/298 (48%), Gaps = 31/298 (10%)
Query: 566 PVTQELTRFLVDPAHLVTYDIL-GTGRFGRVHLG----VLQVPGKAPRPVAVKSLRKGAA 620
P +E+ P +T +L G+G FG V+ G +L V G VAVK+L+KG+
Sbjct: 1923 PTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGV-GSGEIKVAVKTLKKGST 1981
Query: 621 PAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQ 680
E+ EFL EA +M+ +H +I++ +G C+ P +++E GDL YLR+ R
Sbjct: 1982 DQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFY 2041
Query: 681 SDHLSQ-DSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVD----- 734
L+ D D R +HRD+ A NCLV
Sbjct: 2042 GPLLTLVDLVDL--------------CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYT 2087
Query: 735 SRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
S R +K+GDFG+AR D D Y R GL PV WMAPESL G F++ SDVWS G
Sbjct: 2088 SPRIVKIGDFGLAR--DIYKND---YYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG 2142
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+L+ E +TLG +PY + S L VL +V +GGR E P CW + +RP
Sbjct: 2143 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRP 2200
>Z98880-2|CAI42374.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 145 bits (352), Expect = 5e-34
Identities = 106/298 (35%), Positives = 146/298 (48%), Gaps = 31/298 (10%)
Query: 566 PVTQELTRFLVDPAHLVTYDIL-GTGRFGRVHLG----VLQVPGKAPRPVAVKSLRKGAA 620
P +E+ P +T +L G+G FG V+ G +L V G VAVK+L+KG+
Sbjct: 1929 PTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGV-GSGEIKVAVKTLKKGST 1987
Query: 621 PAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQ 680
E+ EFL EA +M+ +H +I++ +G C+ P +++E GDL YLR+ R
Sbjct: 1988 DQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFY 2047
Query: 681 SDHLSQ-DSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVD----- 734
L+ D D R +HRD+ A NCLV
Sbjct: 2048 GPLLTLVDLVDL--------------CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYT 2093
Query: 735 SRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
S R +K+GDFG+AR D D Y R GL PV WMAPESL G F++ SDVWS G
Sbjct: 2094 SPRIVKIGDFGLAR--DIYKND---YYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG 2148
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+L+ E +TLG +PY + S L VL +V +GGR E P CW + +RP
Sbjct: 2149 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRP 2206
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 145 bits (352), Expect = 5e-34
Identities = 99/284 (34%), Positives = 140/284 (49%), Gaps = 21/284 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + + G+A VAVK++ + A+ E EFLNEA +M H++R
Sbjct: 1017 LGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVR 1076
Query: 645 FVGACVAKGPP-LVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXX 703
+G V+KG P LV+ME GDL+ YLR R AE + + +E ++
Sbjct: 1077 LLGV-VSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNP--GRPPPTLQEMIQMAAEIAD 1133
Query: 704 XXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYAC 763
+ VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1134 GMAYLNA--------KKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDY-----YRK 1180
Query: 764 RRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG 823
+GL PV WMAPESL G F+++SD+WS GV++ E +L ++PY S +VL+ V G
Sbjct: 1181 GGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDG 1240
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD--HP 865
G + P CW+ RP E+ L+D HP
Sbjct: 1241 GYLDQPDNCPERVTDLMRMCWQFNPNMRPTFLEIVNLLKDDLHP 1284
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 145 bits (352), Expect = 5e-34
Identities = 99/284 (34%), Positives = 140/284 (49%), Gaps = 21/284 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + + G+A VAVK++ + A+ E EFLNEA +M H++R
Sbjct: 1029 LGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVR 1088
Query: 645 FVGACVAKGPP-LVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXX 703
+G V+KG P LV+ME GDL+ YLR R AE + + +E ++
Sbjct: 1089 LLGV-VSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNP--GRPPPTLQEMIQMAAEIAD 1145
Query: 704 XXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYAC 763
+ VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1146 GMAYLNA--------KKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDY-----YRK 1192
Query: 764 RRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG 823
+GL PV WMAPESL G F+++SD+WS GV++ E +L ++PY S +VL+ V G
Sbjct: 1193 GGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDG 1252
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD--HP 865
G + P CW+ RP E+ L+D HP
Sbjct: 1253 GYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHP 1296
>M13880-1|AAA36580.1| 494|Homo sapiens protein ( Human mcf3
(rearranged ros1) proto-oncogene mRNA encoding a
transmembrane protein kinase, 3' end. ).
Length = 494
Score = 145 bits (352), Expect = 5e-34
Identities = 106/298 (35%), Positives = 146/298 (48%), Gaps = 31/298 (10%)
Query: 566 PVTQELTRFLVDPAHLVTYDIL-GTGRFGRVHLG----VLQVPGKAPRPVAVKSLRKGAA 620
P +E+ P +T +L G+G FG V+ G +L V G VAVK+L+KG+
Sbjct: 76 PTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGV-GSGEIKVAVKTLKKGST 134
Query: 621 PAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQ 680
E+ EFL EA +M+ +H +I++ +G C+ P +++E GDL YLR+ R
Sbjct: 135 DQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFY 194
Query: 681 SDHLSQ-DSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVD----- 734
L+ D D R +HRD+ A NCLV
Sbjct: 195 GPLLTLVDLVDL--------------CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYT 240
Query: 735 SRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
S R +K+GDFG+AR D D Y R GL PV WMAPESL G F++ SDVWS G
Sbjct: 241 SPRIVKIGDFGLAR--DIYKND---YYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG 295
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+L+ E +TLG +PY + S L VL +V +GGR E P CW + +RP
Sbjct: 296 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRP 353
>M13599-1|AAA60277.1| 471|Homo sapiens ROS1 protein.
Length = 471
Score = 145 bits (352), Expect = 5e-34
Identities = 106/298 (35%), Positives = 146/298 (48%), Gaps = 31/298 (10%)
Query: 566 PVTQELTRFLVDPAHLVTYDIL-GTGRFGRVHLG----VLQVPGKAPRPVAVKSLRKGAA 620
P +E+ P +T +L G+G FG V+ G +L V G VAVK+L+KG+
Sbjct: 140 PTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGV-GSGEIKVAVKTLKKGST 198
Query: 621 PAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQ 680
E+ EFL EA +M+ +H +I++ +G C+ P +++E GDL YLR+ R
Sbjct: 199 DQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFY 258
Query: 681 SDHLSQ-DSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVD----- 734
L+ D D R +HRD+ A NCLV
Sbjct: 259 GPLLTLVDLVDL--------------CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYT 304
Query: 735 SRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
S R +K+GDFG+AR D D Y R GL PV WMAPESL G F++ SDVWS G
Sbjct: 305 SPRIVKIGDFGLAR--DIYKND---YYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG 359
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+L+ E +TLG +PY + S L VL +V +GGR E P CW + +RP
Sbjct: 360 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRP 417
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 145 bits (352), Expect = 5e-34
Identities = 99/284 (34%), Positives = 140/284 (49%), Gaps = 21/284 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + + G+A VAVK++ + A+ E EFLNEA +M H++R
Sbjct: 1029 LGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVR 1088
Query: 645 FVGACVAKGPP-LVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXX 703
+G V+KG P LV+ME GDL+ YLR R AE + + +E ++
Sbjct: 1089 LLGV-VSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNP--GRPPPTLQEMIQMAAEIAD 1145
Query: 704 XXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYAC 763
+ VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1146 GMAYLNA--------KKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDY-----YRK 1192
Query: 764 RRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG 823
+GL PV WMAPESL G F+++SD+WS GV++ E +L ++PY S +VL+ V G
Sbjct: 1193 GGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDG 1252
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD--HP 865
G + P CW+ RP E+ L+D HP
Sbjct: 1253 GYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHP 1296
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 145 bits (352), Expect = 5e-34
Identities = 99/284 (34%), Positives = 140/284 (49%), Gaps = 21/284 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + + G+A VAVK++ + A+ E EFLNEA +M H++R
Sbjct: 1017 LGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVR 1076
Query: 645 FVGACVAKGPP-LVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXX 703
+G V+KG P LV+ME GDL+ YLR R AE + + +E ++
Sbjct: 1077 LLGV-VSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNP--GRPPPTLQEMIQMAAEIAD 1133
Query: 704 XXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYAC 763
+ VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1134 GMAYLNA--------KKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDY-----YRK 1180
Query: 764 RRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG 823
+GL PV WMAPESL G F+++SD+WS GV++ E +L ++PY S +VL+ V G
Sbjct: 1181 GGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDG 1240
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD--HP 865
G + P CW+ RP E+ L+D HP
Sbjct: 1241 GYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHP 1284
>AL132671-5|CAI23378.1| 2347|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2347
Score = 145 bits (352), Expect = 5e-34
Identities = 106/298 (35%), Positives = 146/298 (48%), Gaps = 31/298 (10%)
Query: 566 PVTQELTRFLVDPAHLVTYDIL-GTGRFGRVHLG----VLQVPGKAPRPVAVKSLRKGAA 620
P +E+ P +T +L G+G FG V+ G +L V G VAVK+L+KG+
Sbjct: 1929 PTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGV-GSGEIKVAVKTLKKGST 1987
Query: 621 PAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQ 680
E+ EFL EA +M+ +H +I++ +G C+ P +++E GDL YLR+ R
Sbjct: 1988 DQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFY 2047
Query: 681 SDHLSQ-DSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVD----- 734
L+ D D R +HRD+ A NCLV
Sbjct: 2048 GPLLTLVDLVDL--------------CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYT 2093
Query: 735 SRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
S R +K+GDFG+AR D D Y R GL PV WMAPESL G F++ SDVWS G
Sbjct: 2094 SPRIVKIGDFGLAR--DIYKND---YYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG 2148
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+L+ E +TLG +PY + S L VL +V +GGR E P CW + +RP
Sbjct: 2149 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRP 2206
>AL132671-4|CAI23379.1| 2341|Homo sapiens v-ros UR2 sarcoma virus
oncogene homolog 1 (avian) protein.
Length = 2341
Score = 145 bits (352), Expect = 5e-34
Identities = 106/298 (35%), Positives = 146/298 (48%), Gaps = 31/298 (10%)
Query: 566 PVTQELTRFLVDPAHLVTYDIL-GTGRFGRVHLG----VLQVPGKAPRPVAVKSLRKGAA 620
P +E+ P +T +L G+G FG V+ G +L V G VAVK+L+KG+
Sbjct: 1923 PTQEEIENLPAFPREKLTLRLLLGSGAFGEVYEGTAVDILGV-GSGEIKVAVKTLKKGST 1981
Query: 621 PAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQ 680
E+ EFL EA +M+ +H +I++ +G C+ P +++E GDL YLR+ R
Sbjct: 1982 DQEKIEFLKEAHLMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFY 2041
Query: 681 SDHLSQ-DSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVD----- 734
L+ D D R +HRD+ A NCLV
Sbjct: 2042 GPLLTLVDLVDL--------------CVDISKGCVYLERMHFIHRDLAARNCLVSVKDYT 2087
Query: 735 SRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
S R +K+GDFG+AR D D Y R GL PV WMAPESL G F++ SDVWS G
Sbjct: 2088 SPRIVKIGDFGLAR--DIYKND---YYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFG 2142
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+L+ E +TLG +PY + S L VL +V +GGR E P CW + +RP
Sbjct: 2143 ILIWEILTLGHQPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRP 2200
>AB208861-1|BAD92098.1| 833|Homo sapiens insulin receptor variant
protein.
Length = 833
Score = 145 bits (352), Expect = 5e-34
Identities = 99/284 (34%), Positives = 140/284 (49%), Gaps = 21/284 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + + G+A VAVK++ + A+ E EFLNEA +M H++R
Sbjct: 480 LGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVR 539
Query: 645 FVGACVAKGPP-LVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXX 703
+G V+KG P LV+ME GDL+ YLR R AE + + +E ++
Sbjct: 540 LLGV-VSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNP--GRPPPTLQEMIQMAAEIAD 596
Query: 704 XXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYAC 763
+ VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 597 GMAYLNA--------KKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDY-----YRK 643
Query: 764 RRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG 823
+GL PV WMAPESL G F+++SD+WS GV++ E +L ++PY S +VL+ V G
Sbjct: 644 GGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDG 703
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD--HP 865
G + P CW+ RP E+ L+D HP
Sbjct: 704 GYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHP 747
>J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related
receptor protein.
Length = 1268
Score = 143 bits (346), Expect = 3e-33
Identities = 100/289 (34%), Positives = 138/289 (47%), Gaps = 20/289 (6%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G+ + G+ PVA+K++ + A+P E EFL EA +M A H++R
Sbjct: 956 LGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVR 1015
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G P LV+ME GDL+ +LR R AE + L Q + E +
Sbjct: 1016 LLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPAL----GEMIQMAGEIA 1071
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1072 DGMAYLAANKF------VHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDY-----YRKG 1120
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+GL PV WMAPESL G F++ SDVWS GV++ E VTL ++PY S +VL+ V GG
Sbjct: 1121 GKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGG 1180
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
E G CW+ RP+ + +++ LRP R
Sbjct: 1181 VLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQEE---LRPSFR 1226
>AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-related
receptor protein.
Length = 1297
Score = 143 bits (346), Expect = 3e-33
Identities = 100/289 (34%), Positives = 138/289 (47%), Gaps = 20/289 (6%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G+ + G+ PVA+K++ + A+P E EFL EA +M A H++R
Sbjct: 985 LGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKEASVMKAFKCHHVVR 1044
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G P LV+ME GDL+ +LR R AE + L Q + E +
Sbjct: 1045 LLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPEAENNPGLPQPAL----GEMIQMAGEIA 1100
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1101 DGMAYLAANKF------VHRDLAARNCMVSQDFTVKIGDFGMTRDVYETDY-----YRKG 1149
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+GL PV WMAPESL G F++ SDVWS GV++ E VTL ++PY S +VL+ V GG
Sbjct: 1150 GKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGLSNEQVLKFVMDGG 1209
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRALRPVLR 873
E G CW+ RP+ + +++ LRP R
Sbjct: 1210 VLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQEE---LRPSFR 1255
>X52213-1|CAA36460.1| 464|Homo sapiens ltk protein.
Length = 464
Score = 142 bits (343), Expect = 7e-33
Identities = 109/349 (31%), Positives = 159/349 (45%), Gaps = 38/349 (10%)
Query: 561 PAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLG-VLQVPG-KAPRPVAVKSLRKG 618
PA+ P+ +T V PA++ LG G FG V+ G V+ +PG +P VA+K+L +
Sbjct: 93 PAQSWPLPPGVTE--VSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPEL 150
Query: 619 AAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HF 677
+P +E +FL EA+I++ H++I+R VG + P L+L+E GD++ +LR R H
Sbjct: 151 CSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHL 210
Query: 678 AEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLV--DS 735
+ S + +D + +HRD+ A NCL+
Sbjct: 211 GQPSPLVMRDLLQLAQD--------------IAQGCHYLEENHFIHRDIAARNCLLMRGP 256
Query: 736 RRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGV 795
R K+GDFGMAR A+ Y R L PV WM PE+ G F+S +D WS GV
Sbjct: 257 SRVAKIGDFGMARDIYR-----ASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFGV 311
Query: 796 LMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAG 855
L+ E +LG PY + VL V GGR + P G CW+ RP+
Sbjct: 312 LLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSFA 371
Query: 856 EV---ARYLRDHPRALRPVLRSRVAP----DADSGFGESD-----PPSP 892
+ +Y P L +L + P + SG G PP P
Sbjct: 372 SILERLQYCTQDPDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQP 420
>X60702-1|CAA43113.1| 803|Homo sapiens tyrosine kinase protein.
Length = 803
Score = 141 bits (342), Expect = 9e-33
Identities = 109/350 (31%), Positives = 159/350 (45%), Gaps = 39/350 (11%)
Query: 561 PAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLG-VLQVPG-KAPRPVAVKSLRKG 618
PA+ P+ +T V PA++ LG G FG V+ G V+ +PG +P VA+K+L +
Sbjct: 431 PAQSWPLPPGVTE--VSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPEL 488
Query: 619 AAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HF 677
+P +E +FL EA+I++ H++I+R VG + P L+L+E GD++ +LR R H
Sbjct: 489 CSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHL 548
Query: 678 AEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR- 736
+ S + +D + +HRD+ A NCL+
Sbjct: 549 GQPSPLVMRDLLQLAQD--------------IAQGCHYLEENHFIHRDIAARNCLLSCAG 594
Query: 737 --RRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
R K+GDFGMAR A+ Y R L PV WM PE+ G F+S +D WS G
Sbjct: 595 PSRVAKIGDFGMARDIYR-----ASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFG 649
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAA 854
VL+ E +LG PY + VL V GGR + P G CW+ RP+
Sbjct: 650 VLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSF 709
Query: 855 GEV---ARYLRDHPRALRPVLRSRVAP----DADSGFGESD-----PPSP 892
+ +Y P L +L + P + SG G PP P
Sbjct: 710 ASILERLQYCTQDPDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQP 759
>D16105-1|BAA03679.1| 864|Homo sapiens leukocyte tyrosine kinase
protein.
Length = 864
Score = 141 bits (342), Expect = 9e-33
Identities = 109/350 (31%), Positives = 159/350 (45%), Gaps = 39/350 (11%)
Query: 561 PAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLG-VLQVPG-KAPRPVAVKSLRKG 618
PA+ P+ +T V PA++ LG G FG V+ G V+ +PG +P VA+K+L +
Sbjct: 492 PAQSWPLPPGVTE--VSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPEL 549
Query: 619 AAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HF 677
+P +E +FL EA+I++ H++I+R VG + P L+L+E GD++ +LR R H
Sbjct: 550 CSPQDELDFLMEALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHL 609
Query: 678 AEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR- 736
+ S + +D + +HRD+ A NCL+
Sbjct: 610 GQPSPLVMRDLLQLAQD--------------IAQGCHYLEENHFIHRDIAARNCLLSCAG 655
Query: 737 --RRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLG 794
R K+GDFGMAR A+ Y R L PV WM PE+ G F+S +D WS G
Sbjct: 656 PSRVAKIGDFGMARDIYR-----ASYYRRGDRALLPVKWMPPEAFLEGIFTSKTDSWSFG 710
Query: 795 VLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAA 854
VL+ E +LG PY + VL V GGR + P G CW+ RP+
Sbjct: 711 VLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSF 770
Query: 855 GEV---ARYLRDHPRALRPVLRSRVAP----DADSGFGESD-----PPSP 892
+ +Y P L +L + P + SG G PP P
Sbjct: 771 ASILERLQYCTQDPDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQP 820
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 138 bits (335), Expect = 6e-32
Identities = 93/279 (33%), Positives = 133/279 (47%), Gaps = 17/279 (6%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ GV + V + VA+K++ + A+ E EFLNEA +M + H++R
Sbjct: 1005 LGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVR 1064
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G P LV+ME GDL+ YLR R E + L+ S S+ +
Sbjct: 1065 LLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSL----SKMIQMAGEIA 1120
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1121 DGMAYLNANKF------VHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDY-----YRKG 1169
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+GL PV WM+PESL G F++ SDVWS GV++ E TL ++PY S +VL+ V GG
Sbjct: 1170 GKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGG 1229
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
+ P CW+ RP+ E+ +++
Sbjct: 1230 LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKE 1268
>BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 138 bits (335), Expect = 6e-32
Identities = 93/279 (33%), Positives = 133/279 (47%), Gaps = 17/279 (6%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ GV + V + VA+K++ + A+ E EFLNEA +M + H++R
Sbjct: 1005 LGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVR 1064
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G P LV+ME GDL+ YLR R E + L+ S S+ +
Sbjct: 1065 LLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSL----SKMIQMAGEIA 1120
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1121 DGMAYLNANKF------VHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDY-----YRKG 1169
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+GL PV WM+PESL G F++ SDVWS GV++ E TL ++PY S +VL+ V GG
Sbjct: 1170 GKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGG 1229
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
+ P CW+ RP+ E+ +++
Sbjct: 1230 LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKE 1268
>BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 138 bits (335), Expect = 6e-32
Identities = 93/279 (33%), Positives = 133/279 (47%), Gaps = 17/279 (6%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ GV + V + VA+K++ + A+ E EFLNEA +M + H++R
Sbjct: 1005 LGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVR 1064
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G P LV+ME GDL+ YLR R E + L+ S S+ +
Sbjct: 1065 LLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSL----SKMIQMAGEIA 1120
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1121 DGMAYLNANKF------VHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDY-----YRKG 1169
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+GL PV WM+PESL G F++ SDVWS GV++ E TL ++PY S +VL+ V GG
Sbjct: 1170 GKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGG 1229
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
+ P CW+ RP+ E+ +++
Sbjct: 1230 LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKE 1268
>AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth factor 1
receptor protein.
Length = 1367
Score = 138 bits (335), Expect = 6e-32
Identities = 93/279 (33%), Positives = 133/279 (47%), Gaps = 17/279 (6%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ GV + V + VA+K++ + A+ E EFLNEA +M + H++R
Sbjct: 1005 LGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVR 1064
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G P LV+ME GDL+ YLR R E + L+ S S+ +
Sbjct: 1065 LLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSL----SKMIQMAGEIA 1120
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ A NC+V +K+GDFGM R T Y
Sbjct: 1121 DGMAYLNANKF------VHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDY-----YRKG 1169
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+GL PV WM+PESL G F++ SDVWS GV++ E TL ++PY S +VL+ V GG
Sbjct: 1170 GKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGG 1229
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
+ P CW+ RP+ E+ +++
Sbjct: 1230 LLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKE 1268
>M59371-1|AAA53375.1| 976|Homo sapiens protein-tyrosine kinase
protein.
Length = 976
Score = 133 bits (322), Expect = 2e-30
Identities = 92/310 (29%), Positives = 138/310 (44%), Gaps = 26/310 (8%)
Query: 555 LASVIRPAKLPPVTQELTRFLVD--PAHLVTYDILGTGRFGRVHLGVLQVP-GKAPRPVA 611
L + + P Q + +F + P+ + ++G G FG V+ G+L+ GK PVA
Sbjct: 585 LKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVA 644
Query: 612 VKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYL 671
+K+L+ G + +FL EA IM H +IIR G P +++ E+ G L ++L
Sbjct: 645 IKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFL 704
Query: 672 RERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNC 731
RE KD E S VHRD+ A N
Sbjct: 705 RE---------------KDGE----FSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNI 745
Query: 732 LVDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVW 791
LV+S K+ DFG++R + D A Y G P+ W APE++S F+SASDVW
Sbjct: 746 LVNSNLVCKVSDFGLSRVLED---DPEATYTTSG-GKIPIRWTAPEAISYRKFTSASDVW 801
Query: 792 SLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACER 851
S G++M E +T G+RPY S V++ ++ G R P CW++ R
Sbjct: 802 SFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARR 861
Query: 852 PAAGEVARYL 861
P ++ L
Sbjct: 862 PKFADIVSIL 871
>BC037166-1|AAH37166.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 133 bits (322), Expect = 2e-30
Identities = 92/310 (29%), Positives = 138/310 (44%), Gaps = 26/310 (8%)
Query: 555 LASVIRPAKLPPVTQELTRFLVD--PAHLVTYDILGTGRFGRVHLGVLQVP-GKAPRPVA 611
L + + P Q + +F + P+ + ++G G FG V+ G+L+ GK PVA
Sbjct: 585 LKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVA 644
Query: 612 VKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYL 671
+K+L+ G + +FL EA IM H +IIR G P +++ E+ G L ++L
Sbjct: 645 IKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFL 704
Query: 672 RERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNC 731
RE KD E S VHRD+ A N
Sbjct: 705 RE---------------KDGE----FSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNI 745
Query: 732 LVDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVW 791
LV+S K+ DFG++R + D A Y G P+ W APE++S F+SASDVW
Sbjct: 746 LVNSNLVCKVSDFGLSRVLED---DPEATYTTSG-GKIPIRWTAPEAISYRKFTSASDVW 801
Query: 792 SLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACER 851
S G++M E +T G+RPY S V++ ++ G R P CW++ R
Sbjct: 802 SFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARR 861
Query: 852 PAAGEVARYL 861
P ++ L
Sbjct: 862 PKFADIVSIL 871
>AL451042-1|CAH71943.1| 976|Homo sapiens EPH receptor A2 protein.
Length = 976
Score = 133 bits (322), Expect = 2e-30
Identities = 92/310 (29%), Positives = 138/310 (44%), Gaps = 26/310 (8%)
Query: 555 LASVIRPAKLPPVTQELTRFLVD--PAHLVTYDILGTGRFGRVHLGVLQVP-GKAPRPVA 611
L + + P Q + +F + P+ + ++G G FG V+ G+L+ GK PVA
Sbjct: 585 LKTYVDPHTYEDPNQAVLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVA 644
Query: 612 VKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYL 671
+K+L+ G + +FL EA IM H +IIR G P +++ E+ G L ++L
Sbjct: 645 IKTLKAGYTEKQRVDFLGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFL 704
Query: 672 RERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNC 731
RE KD E S VHRD+ A N
Sbjct: 705 RE---------------KDGE----FSVLQLVGMLRGIAAGMKYLANMNYVHRDLAARNI 745
Query: 732 LVDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVW 791
LV+S K+ DFG++R + D A Y G P+ W APE++S F+SASDVW
Sbjct: 746 LVNSNLVCKVSDFGLSRVLED---DPEATYTTSG-GKIPIRWTAPEAISYRKFTSASDVW 801
Query: 792 SLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACER 851
S G++M E +T G+RPY S V++ ++ G R P CW++ R
Sbjct: 802 SFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPMDCPSAIYQLMMQCWQQERARR 861
Query: 852 PAAGEVARYL 861
P ++ L
Sbjct: 862 PKFADIVSIL 871
>Z27409-1|CAA81796.1| 691|Homo sapiens receptor tyrosine kinase eph
protein.
Length = 691
Score = 130 bits (314), Expect = 2e-29
Identities = 89/305 (29%), Positives = 135/305 (44%), Gaps = 28/305 (9%)
Query: 570 ELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLN 629
+ TR L DPA L+ ++G G FG V+ G L++P + + VA+K+L+ + + FL
Sbjct: 329 DFTREL-DPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLR 387
Query: 630 EAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSK 689
EA IM H HI+ G + P +++ E G L +LRE + D L
Sbjct: 388 EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQ- 440
Query: 690 DFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARK 749
VHRD+ A N LV+ K+ DFG+ R
Sbjct: 441 ------------LVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 488
Query: 750 TDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYG 809
D DG E + G P+ W APE+++ F++ASDVWS G++M E ++ GD+PYG
Sbjct: 489 LD--DFDGTYE---TQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 543
Query: 810 SWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD---HPR 866
S V++ + G R P CW RP ++ +L +P
Sbjct: 544 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 603
Query: 867 ALRPV 871
+LR +
Sbjct: 604 SLRTI 608
>X95425-1|CAA64700.1| 1037|Homo sapiens EHK-1 receptor tyrosine
kinase protein.
Length = 1037
Score = 130 bits (314), Expect = 2e-29
Identities = 85/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK PVA+K+L+ G + +FL EA IM DH +II
Sbjct: 680 VIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHL 739
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E+ G L + L ++ F + V
Sbjct: 740 EGVVTKSKPVMIVTEYMENGSLDTF-------------LKKNDGQFTVIQLVGMLRGISA 786
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N L++S K+ DFG++R + D A Y R
Sbjct: 787 GMKYLSDM------GYVHRDLAARNILINSNLVCKVSDFGLSRVLED---DPEAAYTTRG 837
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE+++ F+SASDVWS G++M E V+ G+RPY + V++ V G R
Sbjct: 838 -GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 896
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP E+ L
Sbjct: 897 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 932
>L40636-1|AAB08520.1| 984|Homo sapiens protein tyrosine kinase
protein.
Length = 984
Score = 130 bits (314), Expect = 2e-29
Identities = 89/306 (29%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + +++G G FG V+ G L++PGK VA+K+L+ G + + +FL+EA IM
Sbjct: 614 IDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMG 673
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +IIR G P +++ E G L +LR Q+ F +
Sbjct: 674 QFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR-------------QNDGQFTVIQ 720
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V VHRD+ A N LV+S K+ DFG++R +
Sbjct: 721 LVGMLRGIAAGMKYLA------EMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTS 774
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D Y G PV W APE+++ F+SASDVWS G++M E ++ G+RPY S
Sbjct: 775 DPT--YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD---HPRALRPVL 872
V+ + R P CW++ RP E+ L +P +L+ V
Sbjct: 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892
Query: 873 RSRVAP 878
P
Sbjct: 893 TITAVP 898
>L36644-1|AAA74245.1| 991|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 991
Score = 130 bits (314), Expect = 2e-29
Identities = 85/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK PVA+K+L+ G + +FL EA IM DH +II
Sbjct: 634 VIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHL 693
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E+ G L + L ++ F + V
Sbjct: 694 EGVVTKSKPVMIVTEYMENGSLDTF-------------LKKNDGQFTVIQLVGMLRGISA 740
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N L++S K+ DFG++R + D A Y R
Sbjct: 741 GMKYLSDM------GYVHRDLAARNILINSNLVCKVSDFGLSRVLED---DPEAAYTTRG 791
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE+++ F+SASDVWS G++M E V+ G+RPY + V++ V G R
Sbjct: 792 -GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 850
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP E+ L
Sbjct: 851 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 886
>BC130291-1|AAI30292.1| 976|Homo sapiens EPH receptor A1 protein.
Length = 976
Score = 130 bits (314), Expect = 2e-29
Identities = 89/305 (29%), Positives = 135/305 (44%), Gaps = 28/305 (9%)
Query: 570 ELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLN 629
+ TR L DPA L+ ++G G FG V+ G L++P + + VA+K+L+ + + FL
Sbjct: 614 DFTREL-DPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLR 672
Query: 630 EAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSK 689
EA IM H HI+ G + P +++ E G L +LRE + D L
Sbjct: 673 EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQ- 725
Query: 690 DFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARK 749
VHRD+ A N LV+ K+ DFG+ R
Sbjct: 726 ------------LVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 773
Query: 750 TDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYG 809
D DG E + G P+ W APE+++ F++ASDVWS G++M E ++ GD+PYG
Sbjct: 774 LD--DFDGTYE---TQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 828
Query: 810 SWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD---HPR 866
S V++ + G R P CW RP ++ +L +P
Sbjct: 829 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 888
Query: 867 ALRPV 871
+LR +
Sbjct: 889 SLRTI 893
>AF101171-1|AAD43440.1| 976|Homo sapiens receptor tyrosine kinase
protein.
Length = 976
Score = 130 bits (314), Expect = 2e-29
Identities = 89/305 (29%), Positives = 135/305 (44%), Gaps = 28/305 (9%)
Query: 570 ELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLN 629
+ TR L DPA L+ ++G G FG V+ G L++P + + VA+K+L+ + + FL
Sbjct: 614 DFTREL-DPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLR 672
Query: 630 EAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSK 689
EA IM H HI+ G + P +++ E G L +LRE + D L
Sbjct: 673 EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQ- 725
Query: 690 DFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARK 749
VHRD+ A N LV+ K+ DFG+ R
Sbjct: 726 ------------LVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 773
Query: 750 TDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYG 809
D DG E + G P+ W APE+++ F++ASDVWS G++M E ++ GD+PYG
Sbjct: 774 LD--DFDGTYE---TQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 828
Query: 810 SWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD---HPR 866
S V++ + G R P CW RP ++ +L +P
Sbjct: 829 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 888
Query: 867 ALRPV 871
+LR +
Sbjct: 889 SLRTI 893
>AC092214-2|AAS07458.1| 976|Homo sapiens unknown protein.
Length = 976
Score = 130 bits (314), Expect = 2e-29
Identities = 89/305 (29%), Positives = 135/305 (44%), Gaps = 28/305 (9%)
Query: 570 ELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLN 629
+ TR L DPA L+ ++G G FG V+ G L++P + + VA+K+L+ + + FL
Sbjct: 614 DFTREL-DPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLR 672
Query: 630 EAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSK 689
EA IM H HI+ G + P +++ E G L +LRE + D L
Sbjct: 673 EATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLRE------REDQLVPGQ- 725
Query: 690 DFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARK 749
VHRD+ A N LV+ K+ DFG+ R
Sbjct: 726 ------------LVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRL 773
Query: 750 TDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYG 809
D DG E + G P+ W APE+++ F++ASDVWS G++M E ++ GD+PYG
Sbjct: 774 LD--DFDGTYE---TQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYG 828
Query: 810 SWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD---HPR 866
S V++ + G R P CW RP ++ +L +P
Sbjct: 829 EMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPH 888
Query: 867 ALRPV 871
+LR +
Sbjct: 889 SLRTI 893
>AB209375-1|BAD92612.1| 1017|Homo sapiens ephrin receptor EphA5
isoform a variant protein.
Length = 1017
Score = 130 bits (314), Expect = 2e-29
Identities = 85/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK PVA+K+L+ G + +FL EA IM DH +II
Sbjct: 694 VIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHL 753
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E+ G L + L ++ F + V
Sbjct: 754 EGVVTKSKPVMIVTEYMENGSLDTF-------------LKKNDGQFTVIQLVGMLRGISA 800
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N L++S K+ DFG++R + D A Y R
Sbjct: 801 GMKYLSDM------GYVHRDLAARNILINSNLVCKVSDFGLSRVLED---DPEAAYTTRG 851
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE+++ F+SASDVWS G++M E V+ G+RPY + V++ V G R
Sbjct: 852 -GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 910
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP E+ L
Sbjct: 911 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 946
>U66559-1|AAC51104.1| 1620|Homo sapiens anaplastic lymphoma kinase
receptor protein.
Length = 1620
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 1122 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 1181
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 1182 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 1236
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 1237 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 1286
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 1287 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 1343
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 1344 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 1374
>U62540-1|AAB71619.1| 1620|Homo sapiens anaplastic lymphoma kinase
protein.
Length = 1620
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 1122 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 1181
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 1182 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 1236
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 1237 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 1286
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 1287 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 1343
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 1344 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 1374
>U04946-1|AAA58698.1| 680|Homo sapiens nucleophosmin-anaplastic
lymphoma kinase fusion protein protein.
Length = 680
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 182 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 241
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 242 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 296
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 297 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 346
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 347 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 403
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 404 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 434
>D45915-1|BAA08343.1| 680|Homo sapiens p80 protein protein.
Length = 680
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 182 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 241
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 242 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 296
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 297 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 346
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 347 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 403
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 404 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 434
>AF390893-1|AAM17922.1| 803|Homo sapiens TRK-fused gene/anaplastic
large cell lymphoma kinase extra long form protein.
Length = 803
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 305 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 364
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 365 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 419
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 420 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 469
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 470 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 526
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 527 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 557
>AF143407-1|AAF27292.1| 756|Homo sapiens TRK-fused gene/anaplastic
lymphoma kinase (Ki-1) fusion protein long form protein.
Length = 756
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 258 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 317
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 318 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 372
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 373 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 422
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 423 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 479
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 480 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 510
>AF125093-1|AAF42734.1| 701|Homo sapiens TRK-fused gene-anaplastic
lymphoma kinase fusion protein protein.
Length = 701
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 203 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 262
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 263 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 317
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 318 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 367
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 368 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 424
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 425 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 455
>AC074096-1|AAY15027.1| 1192|Homo sapiens unknown protein.
Length = 1192
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 694 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 753
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 754 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 808
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 809 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 858
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 859 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 915
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 916 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 946
>AB209477-1|BAD92714.1| 1626|Homo sapiens anaplastic lymphoma kinase
Ki-1 variant protein.
Length = 1626
Score = 129 bits (312), Expect = 4e-29
Identities = 91/271 (33%), Positives = 130/271 (47%), Gaps = 23/271 (8%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRP--VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG V+ G + P P VAVK+L + + +E +FL EA+I++ +H++I+R
Sbjct: 1128 LGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVR 1187
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G + P +L+E GDL+ +LRE R Q L+ + HV+
Sbjct: 1188 CIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAM-----LDLLHVARDIACG 1242
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSR---RRLKLGDFGMARKTDATGADGAAEY 761
+HRD+ A NCL+ R K+GDFGMAR D A +
Sbjct: 1243 CQYLE--------ENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMAR--DIYRASYYRKG 1292
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
C + PV WM PE+ G F+S +D WS GVL+ E +LG PY S S VL+ V+
Sbjct: 1293 GC---AMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVT 1349
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
SGGR + P CW+ +RP
Sbjct: 1350 SGGRMDPPKNCPGPVYRIMTQCWQHQPEDRP 1380
>BC111744-1|AAI11745.1| 984|Homo sapiens EPH receptor B1 protein.
Length = 984
Score = 129 bits (311), Expect = 5e-29
Identities = 88/306 (28%), Positives = 135/306 (44%), Gaps = 24/306 (7%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + +++G G FG V+ G L++PGK VA+K+L+ G + + +FL+EA IM
Sbjct: 614 IDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMG 673
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +IIR G P +++ E G L +LR Q+ F +
Sbjct: 674 QFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR-------------QNDGQFTVIQ 720
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V VHRD+ A N L++S K+ DFG++R +
Sbjct: 721 LVGMLRGIAAGMKYLA------EMNYVHRDLAARNILLNSNLVCKVSDFGLSRYLQDDTS 774
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D Y G PV W APE+++ F+SASDVWS G++M E ++ G+RPY S
Sbjct: 775 DPT--YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQD 832
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD---HPRALRPVL 872
V+ + R P CW++ RP E+ L +P +L+ V
Sbjct: 833 VINAIEQDYRLPPPMDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892
Query: 873 RSRVAP 878
P
Sbjct: 893 TITAVP 898
>X58957-1|CAA41728.1| 659|Homo sapiens agammaglobulinaemia tyrosine
kinase protein.
Length = 659
Score = 128 bits (310), Expect = 7e-29
Identities = 90/278 (32%), Positives = 128/278 (46%), Gaps = 33/278 (11%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 450
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 451 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 509
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 510 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 546
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 547 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 604
Query: 815 RVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+H++ G R P CW A ERP
Sbjct: 605 ETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERP 642
>U78027-4|AAB64205.1| 659|Homo sapiens Bruton's tyrosine kinase
protein.
Length = 659
Score = 128 bits (310), Expect = 7e-29
Identities = 90/278 (32%), Positives = 128/278 (46%), Gaps = 33/278 (11%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 450
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 451 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 509
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 510 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 546
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 547 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 604
Query: 815 RVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+H++ G R P CW A ERP
Sbjct: 605 ETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERP 642
>U13433-1|AAC51347.1| 657|Homo sapiens Bruton's agammaglobulinemia
tyrosine kinase protein.
Length = 657
Score = 128 bits (310), Expect = 7e-29
Identities = 90/278 (32%), Positives = 128/278 (46%), Gaps = 33/278 (11%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 395 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 448
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 449 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 507
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 508 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 544
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 545 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 602
Query: 815 RVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+H++ G R P CW A ERP
Sbjct: 603 ETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERP 640
>U10087-1|AAB60639.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 128 bits (310), Expect = 7e-29
Identities = 90/278 (32%), Positives = 128/278 (46%), Gaps = 33/278 (11%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 450
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 451 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 509
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 510 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 546
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 547 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 604
Query: 815 RVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+H++ G R P CW A ERP
Sbjct: 605 ETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERP 642
>M18391-1|AAA36747.1| 984|Homo sapiens protein ( Human tyrosine
kinase receptor (eph) mRNA, complete cds. ).
Length = 984
Score = 128 bits (310), Expect = 7e-29
Identities = 91/323 (28%), Positives = 139/323 (43%), Gaps = 28/323 (8%)
Query: 553 RHLASVIR-PAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVA 611
RH ++ R P LP +DPA L+ ++G G FG V+ G L++P + + VA
Sbjct: 603 RHTRTLHREPWTLPGGWSNFPSRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVA 662
Query: 612 VKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYL 671
+K+L+ + + FL EA IM H HI+ G + P +++ E L +L
Sbjct: 663 IKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENAALDAFL 722
Query: 672 RERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNC 731
RE + D L VHRD+ A N
Sbjct: 723 RE------REDQLVPGQ-------------LVAMLQGIASGMNYLSNHNYVHRDLAARNI 763
Query: 732 LVDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVW 791
LV+ K+ DFG+ R D DG E + G P+ W APE+++ F++ASDVW
Sbjct: 764 LVNQNLCCKVSDFGLTRLLD--DFDGTYE---TQGGKIPIRWTAPEAIAHRIFTTASDVW 818
Query: 792 SLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACER 851
S G++M E ++ GD+PYG S V++ + G R P CW R
Sbjct: 819 SFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARR 878
Query: 852 PAAGEVARYLRD---HPRALRPV 871
P ++ +L +P +LR +
Sbjct: 879 PHFQKLQAHLEQLLANPHSLRTI 901
>L31572-1|AAA61479.1| 659|Homo sapiens Bruton agammaglobulinemia
protein.
Length = 659
Score = 128 bits (310), Expect = 7e-29
Identities = 90/278 (32%), Positives = 128/278 (46%), Gaps = 33/278 (11%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 450
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 451 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 509
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 510 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 546
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 547 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 604
Query: 815 RVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+H++ G R P CW A ERP
Sbjct: 605 ETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERP 642
>BC109080-1|AAI09081.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 128 bits (310), Expect = 7e-29
Identities = 90/278 (32%), Positives = 128/278 (46%), Gaps = 33/278 (11%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 450
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 451 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 509
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 510 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 546
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 547 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 604
Query: 815 RVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+H++ G R P CW A ERP
Sbjct: 605 ETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERP 642
>BC109079-1|AAI09080.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 128 bits (310), Expect = 7e-29
Identities = 90/278 (32%), Positives = 128/278 (46%), Gaps = 33/278 (11%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 450
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 451 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 509
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 510 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 546
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 547 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 604
Query: 815 RVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+H++ G R P CW A ERP
Sbjct: 605 ETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERP 642
>AL035422-3|CAB55876.1| 659|Homo sapiens Bruton agammaglobulinemia
tyrosine kinase protein.
Length = 659
Score = 128 bits (310), Expect = 7e-29
Identities = 90/278 (32%), Positives = 128/278 (46%), Gaps = 33/278 (11%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 397 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 450
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 451 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 509
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 510 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 546
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 547 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 604
Query: 815 RVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+H++ G R P CW A ERP
Sbjct: 605 ETAEHIAQGLRLYRPHLASEKVYTIMYSCWHEKADERP 642
>AF037332-1|AAD02031.1| 973|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1b protein.
Length = 973
Score = 128 bits (309), Expect = 9e-29
Identities = 89/306 (29%), Positives = 134/306 (43%), Gaps = 24/306 (7%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + +++G G FG V+ G L++PGK VA+K+L+ G + + +FL+EA IM
Sbjct: 603 IDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMG 662
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +IIR G P +++ E G L +LR Q+ F +
Sbjct: 663 QFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR-------------QNDGQFTVIQ 709
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V VHRD+ A N LV+S K+ DFG++R +
Sbjct: 710 LVGMLRGIAAGMKYLA------EMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTS 763
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D Y G PV W APE+++ F+SASDVWS G+ M E ++ G+RPY S
Sbjct: 764 DPT--YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIRMWEVMSFGERPYWDMSNQD 821
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD---HPRALRPVL 872
V+ + R P CW++ RP E+ L +P +L+ V
Sbjct: 822 VINAIEQDYRLPPPTDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 881
Query: 873 RSRVAP 878
P
Sbjct: 882 TITAVP 887
>BX537946-1|CAD97914.1| 969|Homo sapiens hypothetical protein
protein.
Length = 969
Score = 127 bits (306), Expect = 2e-28
Identities = 84/276 (30%), Positives = 124/276 (44%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK PVA+K+L+ G + +FL EA IM DH +II
Sbjct: 612 VIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIHL 671
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E+ G L + L ++ F + V
Sbjct: 672 EGVVTKSKPVMIVTEYMENGSLDTF-------------LKKNDGQFTVIQLVGMLRGISA 718
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N L++S K+ DF ++R + D A Y R
Sbjct: 719 GMKYLSDM------GYVHRDLAARNILINSNLVCKVSDFELSRVLED---DPEAAYTTRG 769
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE+++ F+SASDVWS G++M E V+ G+RPY + V++ V G R
Sbjct: 770 -GKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYR 828
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP E+ L
Sbjct: 829 LPSPMDCPAALYQLMLDCWQKERNSRPKFDEIVNML 864
>M83941-1|AAA58633.1| 983|Homo sapiens receptor protein kinase
protein.
Length = 983
Score = 126 bits (305), Expect = 3e-28
Identities = 90/309 (29%), Positives = 139/309 (44%), Gaps = 25/309 (8%)
Query: 555 LASVIRPAKLPPVTQELTRFL--VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAV 612
L + + P TQ + F +D ++ ++G G FG V G L++P K VA+
Sbjct: 593 LRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAI 652
Query: 613 KSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLR 672
K+L+ G + +FL EA IM DH +IIR G P +++ E+ G L +LR
Sbjct: 653 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712
Query: 673 ERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCL 732
+H A+ F + V G VHRD+ A N L
Sbjct: 713 --KHDAQ-----------FTVIQLVGMLRGIASGMKYLSDM------GYVHRDLAARNIL 753
Query: 733 VDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWS 792
++S K+ DFG++R + D A Y R G P+ W +PE+++ F+SASDVWS
Sbjct: 754 INSNLVCKVSDFGLSRVLED---DPEAAYTTRG-GKIPIRWTSPEAIAYRKFTSASDVWS 809
Query: 793 LGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G+++ E ++ G+RPY S V++ V G R P CW++ RP
Sbjct: 810 YGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRP 869
Query: 853 AAGEVARYL 861
++ L
Sbjct: 870 KFEQIVSIL 878
>BC063282-1|AAH63282.1| 983|Homo sapiens EPH receptor A3 protein.
Length = 983
Score = 126 bits (305), Expect = 3e-28
Identities = 90/309 (29%), Positives = 139/309 (44%), Gaps = 25/309 (8%)
Query: 555 LASVIRPAKLPPVTQELTRFL--VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAV 612
L + + P TQ + F +D ++ ++G G FG V G L++P K VA+
Sbjct: 593 LRTYVDPHTYEDPTQTVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAI 652
Query: 613 KSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLR 672
K+L+ G + +FL EA IM DH +IIR G P +++ E+ G L +LR
Sbjct: 653 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712
Query: 673 ERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCL 732
+H A+ F + V G VHRD+ A N L
Sbjct: 713 --KHDAQ-----------FTVIQLVGMLRGIASGMKYLSDM------GYVHRDLAARNIL 753
Query: 733 VDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWS 792
++S K+ DFG++R + D A Y R G P+ W +PE+++ F+SASDVWS
Sbjct: 754 INSNLVCKVSDFGLSRVLED---DPEAAYTTRG-GKIPIRWTSPEAIAYRKFTSASDVWS 809
Query: 793 LGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G+++ E ++ G+RPY S V++ V G R P CW++ RP
Sbjct: 810 YGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRP 869
Query: 853 AAGEVARYL 861
++ L
Sbjct: 870 KFEQIVSIL 878
>AF213459-1|AAG43576.1| 983|Homo sapiens ephrin receptor EPHA3
complete form protein.
Length = 983
Score = 126 bits (305), Expect = 3e-28
Identities = 90/309 (29%), Positives = 139/309 (44%), Gaps = 25/309 (8%)
Query: 555 LASVIRPAKLPPVTQELTRFL--VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAV 612
L + + P TQ + F +D ++ ++G G FG V G L++P K VA+
Sbjct: 593 LRTYVDPHTYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAI 652
Query: 613 KSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLR 672
K+L+ G + +FL EA IM DH +IIR G P +++ E+ G L +LR
Sbjct: 653 KTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLR 712
Query: 673 ERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCL 732
+H A+ F + V G VHRD+ A N L
Sbjct: 713 --KHDAQ-----------FTVIQLVGMLRGIASGMKYLSDM------GYVHRDLAARNIL 753
Query: 733 VDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWS 792
++S K+ DFG++R + D A Y R G P+ W +PE+++ F+SASDVWS
Sbjct: 754 INSNLVCKVSDFGLSRVLED---DPEAAYTTRG-GKIPIRWTSPEAIAYRKFTSASDVWS 809
Query: 793 LGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G+++ E ++ G+RPY S V++ V G R P CW++ RP
Sbjct: 810 YGIVLWEVMSYGERPYWEMSNQDVIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRP 869
Query: 853 AAGEVARYL 861
++ L
Sbjct: 870 KFEQIVSIL 878
>AF037331-1|AAD02030.1| 984|Homo sapiens Eph-like receptor tyrosine
kinase hEphB1 protein.
Length = 984
Score = 126 bits (305), Expect = 3e-28
Identities = 89/306 (29%), Positives = 133/306 (43%), Gaps = 24/306 (7%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + +++G G FG V+ G L++PGK VA+K+L+ G + + +FL+EA IM
Sbjct: 614 IDVSFVKIEEVIGAGEFGEVYKGRLKLPGKREIYVAIKTLKAGYSEKQRRDFLSEASIMG 673
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +IIR G P +++ E G L +LR Q+ F +
Sbjct: 674 QFDHPNIIRLEGVVTKSRPVMIITEFMENGALDSFLR-------------QNDGQFTVIQ 720
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V VHRD+ A N LV+S K+ DFG++R +
Sbjct: 721 LVGMLRGIAAGMKYLA------EMNYVHRDLAARNILVNSNLVCKVSDFGLSRYLQDDTS 774
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D Y G PV W APE+++ F+SASDVWS G+ M E + G+RPY S
Sbjct: 775 DPT--YTSSLGGKIPVRWTAPEAIAYRKFTSASDVWSYGIHMWEVMYFGERPYWDMSNQD 832
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD---HPRALRPVL 872
V+ + R P CW++ RP E+ L +P +L+ V
Sbjct: 833 VINAIEQDYRLPPPTDCPAALHQLMLDCWQKDRNSRPRFAEIVNTLDKMIRNPASLKTVA 892
Query: 873 RSRVAP 878
P
Sbjct: 893 TITAVP 898
>U34379-1|AAB60412.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 126 bits (303), Expect = 5e-28
Identities = 89/284 (31%), Positives = 128/284 (45%), Gaps = 31/284 (10%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP+ L +G+G+FG VHLG ++ VA+K++ +G+ E +F+ EA +M
Sbjct: 266 IDPSELAFIKXIGSGQFGVVHLG----EWRSHIQVAIKAINEGSM--SEEDFIEEAKVMM 319
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
L H +++ G C+ + P ++ E G L YLRE + + LS E E
Sbjct: 320 KLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQXICEGME 379
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
++ R G +HRD+ A NCLV S +K+ DFGM R
Sbjct: 380 YLE-------------------RNGYIHRDLAARNCLVSSTCIVKISDFGMTRYV----L 416
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D EY FP+ W PE +SS SDVWS GVLM E T G P+ + S L+
Sbjct: 417 DD--EYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQ 474
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVAR 859
V++ +S G R P CW RP E+ R
Sbjct: 475 VVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLR 518
>L36643-1|AAA74244.1| 970|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 970
Score = 125 bits (301), Expect = 8e-28
Identities = 81/276 (29%), Positives = 122/276 (44%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 610 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 669
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 670 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 716
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 717 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 768
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G FP+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 769 GGKFPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 828
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 829 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 864
>L27071-1|AAA74557.1| 527|Homo sapiens tyrosine kinase protein.
Length = 527
Score = 125 bits (301), Expect = 8e-28
Identities = 89/284 (31%), Positives = 128/284 (45%), Gaps = 31/284 (10%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP+ L +G+G+FG VHLG ++ VA+K++ +G+ E +F+ EA +M
Sbjct: 266 IDPSELAFIKEIGSGQFGVVHLG----EWRSHIQVAIKAINEGSM--SEEDFIEEAKVMM 319
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
L H +++ G C+ + P ++ E G L YLRE + + LS E E
Sbjct: 320 KLSHSKLVQLYGVCIQRKPLYIVTEFMENGCLLNYLRENKGKLRKEMLLSVCQDICEGME 379
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
++ R G +HRD+ A NCLV S +K+ DFGM R
Sbjct: 380 YLE-------------------RNGYIHRDLAARNCLVSSTCIVKISDFGMTRYV----L 416
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D EY FP+ W PE +SS SDVWS GVLM E T G P+ + S L+
Sbjct: 417 DD--EYVSSFGAKFPIKWSPPEVFLFNKYSSKSDVWSFGVLMWEVFTEGKMPFENKSNLQ 474
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVAR 859
V++ +S G R P CW RP E+ R
Sbjct: 475 VVEAISEGFRLYRPHLAPMSIYEVMYSCWHEKPEGRPTFAELLR 518
>X52192-1|CAA36438.1| 822|Homo sapiens c-fes protein.
Length = 822
Score = 124 bits (298), Expect = 2e-27
Identities = 88/290 (30%), Positives = 130/290 (44%), Gaps = 27/290 (9%)
Query: 573 RFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAV 632
+++++ LV + +G G FG V G L+ VAVKS R+ P + +FL EA
Sbjct: 553 KWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTL---VAVKSCRETLPPDLKAKFLQEAR 609
Query: 633 IMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFE 692
I+ H +I+R +G C K P ++ME GD +LR
Sbjct: 610 ILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRT------------------- 650
Query: 693 ESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDA 752
E + + +HRD+ A NCLV + LK+ DFGM+R+
Sbjct: 651 EGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREE-- 708
Query: 753 TGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWS 812
ADG + R + PV W APE+L+ G +SS SDVWS G+L+ ET +LG PY + S
Sbjct: 709 --ADGVYAASGGSRQV-PVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLS 765
Query: 813 PLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLR 862
+ + V GGR P CW +RP+ + + L+
Sbjct: 766 NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQ 815
>AY513657-1|AAS82869.1| 752|Homo sapiens proto-oncogene c-fes
variant 4 protein.
Length = 752
Score = 124 bits (298), Expect = 2e-27
Identities = 88/290 (30%), Positives = 130/290 (44%), Gaps = 27/290 (9%)
Query: 573 RFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAV 632
+++++ LV + +G G FG V G L+ VAVKS R+ P + +FL EA
Sbjct: 483 KWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTL---VAVKSCRETLPPDLKAKFLQEAR 539
Query: 633 IMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFE 692
I+ H +I+R +G C K P ++ME GD +LR
Sbjct: 540 ILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRT------------------- 580
Query: 693 ESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDA 752
E + + +HRD+ A NCLV + LK+ DFGM+R+
Sbjct: 581 EGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREE-- 638
Query: 753 TGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWS 812
ADG + R + PV W APE+L+ G +SS SDVWS G+L+ ET +LG PY + S
Sbjct: 639 --ADGVYAASGGSRQV-PVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLS 695
Query: 813 PLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLR 862
+ + V GGR P CW +RP+ + + L+
Sbjct: 696 NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQ 745
>AY513656-1|AAS82868.1| 764|Homo sapiens proto-oncogene c-fes
variant 3 protein.
Length = 764
Score = 124 bits (298), Expect = 2e-27
Identities = 88/290 (30%), Positives = 130/290 (44%), Gaps = 27/290 (9%)
Query: 573 RFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAV 632
+++++ LV + +G G FG V G L+ VAVKS R+ P + +FL EA
Sbjct: 495 KWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTL---VAVKSCRETLPPDLKAKFLQEAR 551
Query: 633 IMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFE 692
I+ H +I+R +G C K P ++ME GD +LR
Sbjct: 552 ILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRT------------------- 592
Query: 693 ESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDA 752
E + + +HRD+ A NCLV + LK+ DFGM+R+
Sbjct: 593 EGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREE-- 650
Query: 753 TGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWS 812
ADG + R + PV W APE+L+ G +SS SDVWS G+L+ ET +LG PY + S
Sbjct: 651 --ADGVYAASGGSRQV-PVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLS 707
Query: 813 PLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLR 862
+ + V GGR P CW +RP+ + + L+
Sbjct: 708 NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQ 757
>AY513654-1|AAS82866.1| 694|Homo sapiens proto-oncogene c-fes
variant 1 protein.
Length = 694
Score = 124 bits (298), Expect = 2e-27
Identities = 88/290 (30%), Positives = 130/290 (44%), Gaps = 27/290 (9%)
Query: 573 RFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAV 632
+++++ LV + +G G FG V G L+ VAVKS R+ P + +FL EA
Sbjct: 425 KWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTL---VAVKSCRETLPPDLKAKFLQEAR 481
Query: 633 IMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFE 692
I+ H +I+R +G C K P ++ME GD +LR
Sbjct: 482 ILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRT------------------- 522
Query: 693 ESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDA 752
E + + +HRD+ A NCLV + LK+ DFGM+R+
Sbjct: 523 EGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREE-- 580
Query: 753 TGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWS 812
ADG + R + PV W APE+L+ G +SS SDVWS G+L+ ET +LG PY + S
Sbjct: 581 --ADGVYAASGGSRQV-PVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLS 637
Query: 813 PLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLR 862
+ + V GGR P CW +RP+ + + L+
Sbjct: 638 NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQ 687
>X06292-1|CAA29619.1| 822|Homo sapiens NCP92 protein.
Length = 822
Score = 123 bits (297), Expect = 2e-27
Identities = 88/290 (30%), Positives = 130/290 (44%), Gaps = 27/290 (9%)
Query: 573 RFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAV 632
+++++ LV + +G G FG V G L+ VAVKS R+ P + +FL EA
Sbjct: 553 KWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTL---VAVKSCRETLPPDLKAKFLQEAR 609
Query: 633 IMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFE 692
I+ H +I+R +G C K P ++ME GD +LR
Sbjct: 610 ILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRT------------------- 650
Query: 693 ESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDA 752
E + + +HRD+ A NCLV + LK+ DFGM+R+
Sbjct: 651 EGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREE-- 708
Query: 753 TGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWS 812
ADG + R + PV W APE+L+ G +SS SDVWS G+L+ ET +LG PY + S
Sbjct: 709 --ADGVYAASGGLRQV-PVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLS 765
Query: 813 PLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLR 862
+ + V GGR P CW +RP+ + + L+
Sbjct: 766 NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQ 815
>BC035357-1|AAH35357.1| 822|Homo sapiens feline sarcoma oncogene
protein.
Length = 822
Score = 123 bits (297), Expect = 2e-27
Identities = 88/290 (30%), Positives = 130/290 (44%), Gaps = 27/290 (9%)
Query: 573 RFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAV 632
+++++ LV + +G G FG V G L+ VAVKS R+ P + +FL EA
Sbjct: 553 KWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTL---VAVKSCRETLPPDLKAKFLQEAR 609
Query: 633 IMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFE 692
I+ H +I+R +G C K P ++ME GD +LR
Sbjct: 610 ILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRT------------------- 650
Query: 693 ESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDA 752
E + + +HRD+ A NCLV + LK+ DFGM+R+
Sbjct: 651 EGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREE-- 708
Query: 753 TGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWS 812
ADG + R + PV W APE+L+ G +SS SDVWS G+L+ ET +LG PY + S
Sbjct: 709 --ADGVYAASGGLRQV-PVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPNLS 765
Query: 813 PLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLR 862
+ + V GGR P CW +RP+ + + L+
Sbjct: 766 NQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQ 815
>L36642-1|AAA74243.1| 998|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 998
Score = 123 bits (296), Expect = 3e-27
Identities = 84/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL EA IM DH +++
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P ++++E G L +L R+H + F + V
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFL--RKHDGQ-----------FTVIQLVGMLRGIAA 744
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N LV+S K+ DFG++R + D A Y
Sbjct: 745 GMRYLADM------GYVHRDLAARNILVNSNLVCKVSDFGLSRVIED---DPEAVYTTTG 795
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G PV W APE++ F+SASDVWS G++M E ++ G+RPY S V++ + G R
Sbjct: 796 -GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 854
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ ERP ++ L
Sbjct: 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
>BC126151-1|AAI26152.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 123 bits (296), Expect = 3e-27
Identities = 84/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL EA IM DH +++
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P ++++E G L +L R+H + F + V
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFL--RKHDGQ-----------FTVIQLVGMLRGIAA 744
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N LV+S K+ DFG++R + D A Y
Sbjct: 745 GMRYLADM------GYVHRDLAARNILVNSNLVCKVSDFGLSRVIED---DPEAVYTTTG 795
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G PV W APE++ F+SASDVWS G++M E ++ G+RPY S V++ + G R
Sbjct: 796 -GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 854
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ ERP ++ L
Sbjct: 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
>BC126125-1|AAI26126.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 123 bits (296), Expect = 3e-27
Identities = 84/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL EA IM DH +++
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P ++++E G L +L R+H + F + V
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFL--RKHDGQ-----------FTVIQLVGMLRGIAA 744
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N LV+S K+ DFG++R + D A Y
Sbjct: 745 GMRYLADM------GYVHRDLAARNILVNSNLVCKVSDFGLSRVIED---DPEAVYTTTG 795
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G PV W APE++ F+SASDVWS G++M E ++ G+RPY S V++ + G R
Sbjct: 796 -GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 854
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ ERP ++ L
Sbjct: 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
>AL591036-1|CAH73650.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 123 bits (296), Expect = 3e-27
Identities = 84/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL EA IM DH +++
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P ++++E G L +L R+H + F + V
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFL--RKHDGQ-----------FTVIQLVGMLRGIAA 744
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N LV+S K+ DFG++R + D A Y
Sbjct: 745 GMRYLADM------GYVHRDLAARNILVNSNLVCKVSDFGLSRVIED---DPEAVYTTTG 795
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G PV W APE++ F+SASDVWS G++M E ++ G+RPY S V++ + G R
Sbjct: 796 -GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 854
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ ERP ++ L
Sbjct: 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
>AL354857-1|CAH72780.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 123 bits (296), Expect = 3e-27
Identities = 84/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL EA IM DH +++
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P ++++E G L +L R+H + F + V
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFL--RKHDGQ-----------FTVIQLVGMLRGIAA 744
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N LV+S K+ DFG++R + D A Y
Sbjct: 745 GMRYLADM------GYVHRDLAARNILVNSNLVCKVSDFGLSRVIED---DPEAVYTTTG 795
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G PV W APE++ F+SASDVWS G++M E ++ G+RPY S V++ + G R
Sbjct: 796 -GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 854
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ ERP ++ L
Sbjct: 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
>AL121966-2|CAI19722.1| 998|Homo sapiens EPH receptor A7 protein.
Length = 998
Score = 123 bits (296), Expect = 3e-27
Identities = 84/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL EA IM DH +++
Sbjct: 638 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 697
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P ++++E G L +L R+H + F + V
Sbjct: 698 EGVVTRGKPVMIVIEFMENGALDAFL--RKHDGQ-----------FTVIQLVGMLRGIAA 744
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N LV+S K+ DFG++R + D A Y
Sbjct: 745 GMRYLADM------GYVHRDLAARNILVNSNLVCKVSDFGLSRVIED---DPEAVYTTTG 795
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G PV W APE++ F+SASDVWS G++M E ++ G+RPY S V++ + G R
Sbjct: 796 -GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 854
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ ERP ++ L
Sbjct: 855 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 890
>AB209269-1|BAD92506.1| 1000|Homo sapiens ephrin receptor EphA7
variant protein.
Length = 1000
Score = 123 bits (296), Expect = 3e-27
Identities = 84/276 (30%), Positives = 125/276 (45%), Gaps = 23/276 (8%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL EA IM DH +++
Sbjct: 640 VIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHL 699
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P ++++E G L +L R+H + F + V
Sbjct: 700 EGVVTRGKPVMIVIEFMENGALDAFL--RKHDGQ-----------FTVIQLVGMLRGIAA 746
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
G VHRD+ A N LV+S K+ DFG++R + D A Y
Sbjct: 747 GMRYLADM------GYVHRDLAARNILVNSNLVCKVSDFGLSRVIED---DPEAVYTTTG 797
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G PV W APE++ F+SASDVWS G++M E ++ G+RPY S V++ + G R
Sbjct: 798 -GKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYR 856
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ ERP ++ L
Sbjct: 857 LPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGIL 892
>L41939-1|AAA99310.1| 987|Homo sapiens protein-tyrosine kinase
protein.
Length = 987
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 627 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 687 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 733
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 734 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 785
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 786 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 845
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 846 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 881
>D37827-1|BAA07073.1| 478|Homo sapiens large erk/cek5 tyrosine
kinase protein.
Length = 478
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 118 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 177
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 178 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 224
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 225 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 276
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 277 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 336
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 337 LPPPMDCPAALHQLMLDCWQKDRNHRPKFGQIVNTL 372
>D31661-1|BAA06506.1| 981|Homo sapiens tyrosine kinase precursor
protein.
Length = 981
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 621 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 680
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 681 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 727
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 728 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 779
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 780 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 839
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 840 LPPPMDCPAALHQLMLDCWQKDRNHRPKFGQIVNTL 875
>AL512444-4|CAI16429.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 732
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 733 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 784
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 785 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 845 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
>AL512444-3|CAI16428.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 627 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 687 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 733
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 734 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 785
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 786 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 845
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 846 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 881
>AL512444-2|CAI16430.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 732
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 733 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 784
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 785 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 845 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
>AL512444-1|CAI16427.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 621 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 680
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 681 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 727
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 728 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 779
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 780 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 839
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 840 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 875
>AL158086-8|CAI22898.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 732
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 733 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 784
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 785 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 845 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
>AL158086-7|CAI22899.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 732
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 733 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 784
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 785 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 845 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
>AL158086-6|CAI22897.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 627 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 687 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 733
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 734 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 785
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 786 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 845
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 846 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 881
>AL035704-4|CAI22646.1| 1055|Homo sapiens EPH receptor B2 protein.
Length = 1055
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 732
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 733 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 784
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 785 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 845 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
>AL035704-3|CAI22645.1| 987|Homo sapiens EPH receptor B2 protein.
Length = 987
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 627 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 686
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 687 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 733
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 734 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 785
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 786 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 845
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 846 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 881
>AL035704-2|CAI22647.2| 986|Homo sapiens EPH receptor B2 protein.
Length = 986
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 732
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 733 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 784
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 785 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 845 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
>AL035704-1|CAI22644.1| 946|Homo sapiens EPH receptor B2 protein.
Length = 946
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 621 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 680
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 681 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 727
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 728 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 779
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 780 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 839
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 840 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 875
>AF025304-1|AAB94602.1| 1055|Homo sapiens protein-tyrosine kinase
EPHB2v protein.
Length = 1055
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 626 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 685
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 686 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 732
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 733 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 784
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 785 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 844
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 845 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 880
>AB210018-1|BAE06100.1| 1004|Homo sapiens EPHB2 variant protein
protein.
Length = 1004
Score = 122 bits (295), Expect = 4e-27
Identities = 80/276 (28%), Positives = 121/276 (43%), Gaps = 21/276 (7%)
Query: 586 ILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRF 645
++G G FG V G L++PGK VA+K+L+ G + +FL+EA IM DH ++I
Sbjct: 644 VIGAGEFGEVCSGHLKLPGKREIFVAIKTLKSGYTEKQRRDFLSEASIMGQFDHPNVIHL 703
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
G P +++ E G L +LR Q+ F + V
Sbjct: 704 EGVVTKSTPVMIITEFMENGSLDSFLR-------------QNDGQFTVIQLVGMLRGIAA 750
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N LV+S K+ DFG++R + +D Y
Sbjct: 751 GMKYLADM------NYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDTSDPT--YTSAL 802
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G P+ W APE++ F+SASDVWS G++M E ++ G+RPY + V+ + R
Sbjct: 803 GGKIPIRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMTNQDVINAIEQDYR 862
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
P CW++ RP G++ L
Sbjct: 863 LPPPMDCPSALHQLMLDCWQKDRNHRPKFGQIVNTL 898
>X62947-1|CAA44719.1| 503|Homo sapiens 55 kd protein protein.
Length = 503
Score = 122 bits (294), Expect = 6e-27
Identities = 82/273 (30%), Positives = 123/273 (45%), Gaps = 13/273 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L +P + VAVK+L++ + A + +F EA ++ L H+HI+R
Sbjct: 223 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ-DFQREAELLTMLQHQHIVR 281
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P L++ E+ GDL R+LR A+ L +D +
Sbjct: 282 FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAK----LLAGGEDVAPGP-LGLGQLLA 336
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 337 VASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY-----YRVG 391
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
R + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S + ++ G
Sbjct: 392 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 451
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P CW+R +R + +V
Sbjct: 452 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDV 484
>M35296-1|AAA35553.1| 1182|Homo sapiens protein ( Human tyrosine
kinase arg gene mRNA. ).
Length = 1182
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 294 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 348
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 349 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 390
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 391 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 444
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 445 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 504
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 505 EQPEGCPPKVYELMRACWKWSPADRPSFAE 534
>M23102-1|AAA36770.1| 790|Homo sapiens protein ( Human trk
proto-oncogene insert of pLM6. ).
Length = 790
Score = 122 bits (294), Expect = 6e-27
Identities = 82/273 (30%), Positives = 123/273 (45%), Gaps = 13/273 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L +P + VAVK+L++ + A + +F EA ++ L H+HI+R
Sbjct: 510 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ-DFQREAELLTMLQHQHIVR 568
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P L++ E+ GDL R+LR A+ L +D +
Sbjct: 569 FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAK----LLAGGEDVAPGP-LGLGQLLA 623
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 624 VASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY-----YRVG 678
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
R + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S + ++ G
Sbjct: 679 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 738
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P CW+R +R + +V
Sbjct: 739 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDV 771
>DQ009672-1|AAY16984.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 294 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 348
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 349 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 390
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 391 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 444
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 445 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 504
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 505 EQPEGCPPKVYELMRACWKWSPADRPSFAE 534
>BX538317-1|CAD98092.1| 1092|Homo sapiens hypothetical protein
protein.
Length = 1092
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 307 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 361
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 362 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 403
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 404 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 457
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 458 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 517
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 518 EQPEGCPPKVYELMRACWKWSPADRPSFAE 547
>BC065912-1|AAH65912.1| 1167|Homo sapiens ABL2 protein protein.
Length = 1167
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 279 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 333
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 334 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 375
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 376 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 429
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 430 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 489
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 490 EQPEGCPPKVYELMRACWKWSPADRPSFAE 519
>BC062580-1|AAH62580.1| 795|Homo sapiens NTRK1 protein protein.
Length = 795
Score = 122 bits (294), Expect = 6e-27
Identities = 82/273 (30%), Positives = 123/273 (45%), Gaps = 13/273 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L +P + VAVK+L++ + A + +F EA ++ L H+HI+R
Sbjct: 515 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ-DFQREAELLTMLQHQHIVR 573
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P L++ E+ GDL R+LR A+ L +D +
Sbjct: 574 FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAK----LLAGGEDVAPGP-LGLGQLLA 628
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 629 VASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY-----YRVG 683
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
R + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S + ++ G
Sbjct: 684 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 743
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P CW+R +R + +V
Sbjct: 744 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDV 776
>AL512326-6|CAI13570.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 294 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 348
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 349 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 390
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 391 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 444
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 445 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 504
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 505 EQPEGCPPKVYELMRACWKWSPADRPSFAE 534
>AL512326-2|CAI13566.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 279 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 333
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 334 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 375
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 376 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 429
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 430 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 489
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 490 EQPEGCPPKVYELMRACWKWSPADRPSFAE 519
>AL359179-2|CAI15585.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 294 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 348
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 349 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 390
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 391 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 444
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 445 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 504
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 505 EQPEGCPPKVYELMRACWKWSPADRPSFAE 534
>AL359179-1|CAI15584.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 279 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 333
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 334 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 375
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 376 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 429
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 430 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 489
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 490 EQPEGCPPKVYELMRACWKWSPADRPSFAE 519
>AL158169-4|CAH70010.1| 790|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 1 protein.
Length = 790
Score = 122 bits (294), Expect = 6e-27
Identities = 82/273 (30%), Positives = 123/273 (45%), Gaps = 13/273 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L +P + VAVK+L++ + A + +F EA ++ L H+HI+R
Sbjct: 510 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ-DFQREAELLTMLQHQHIVR 568
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P L++ E+ GDL R+LR A+ L +D +
Sbjct: 569 FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAK----LLAGGEDVAPGP-LGLGQLLA 623
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 624 VASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY-----YRVG 678
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
R + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S + ++ G
Sbjct: 679 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 738
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P CW+R +R + +V
Sbjct: 739 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDV 771
>AL139132-5|CAH70925.1| 1182|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1182
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 294 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 348
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 349 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 390
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 391 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 444
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 445 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 504
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 505 EQPEGCPPKVYELMRACWKWSPADRPSFAE 534
>AL139132-1|CAH70921.1| 1064|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 2 (arg, Abelson-related
ge protein.
Length = 1064
Score = 122 bits (294), Expect = 6e-27
Identities = 82/270 (30%), Positives = 122/270 (45%), Gaps = 29/270 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V++GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 279 LGGGQYGEVYVGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 333
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E+ +G+L YLRE E V+
Sbjct: 334 GVCTLEPPFYIVTEYMPYGNLLDYLRECNR------------------EEVTAVVLLYMA 375
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 376 TQISSAMEYLEKKNFIHRDLAARNCLVGENHVVKVADFGLSRLM--TGDT----YTAHAG 429
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + G R
Sbjct: 430 AKFPIKWTAPESLAYNTFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYDLLEKGYRM 489
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGE 856
E P G CW+ + +RP+ E
Sbjct: 490 EQPEGCPPKVYELMRACWKWSPADRPSFAE 519
>AB019488-1|BAA34355.1| 796|Homo sapiens TRKA protein.
Length = 796
Score = 122 bits (294), Expect = 6e-27
Identities = 82/273 (30%), Positives = 123/273 (45%), Gaps = 13/273 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L +P + VAVK+L++ + A + +F EA ++ L H+HI+R
Sbjct: 516 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ-DFQREAELLTMLQHQHIVR 574
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P L++ E+ GDL R+LR A+ L +D +
Sbjct: 575 FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAK----LLAGGEDVAPGP-LGLGQLLA 629
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 630 VASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY-----YRVG 684
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
R + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S + ++ G
Sbjct: 685 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 744
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P CW+R +R + +V
Sbjct: 745 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDV 777
>X85960-1|CAA59936.1| 591|Homo sapiens p68 TRK-T3 oncoprotein
protein.
Length = 591
Score = 122 bits (293), Expect = 7e-27
Identities = 82/273 (30%), Positives = 123/273 (45%), Gaps = 13/273 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L +P + VAVK+L++ + A + +F EA ++ L H+HI+R
Sbjct: 311 LGEGAFGKVFLAESHNLLPEQDKMLVAVKALKEASESARQ-DFQREAELLTMLQHQHIVR 369
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P L++ E+ GDL R+LR A+ L +D +
Sbjct: 370 FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAK----LLAGGEDVAPGP-LGLGQLLA 424
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 425 VASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY-----YRVG 479
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
R + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S + ++ G
Sbjct: 480 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 539
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P CW+R +R + +V
Sbjct: 540 ELERPRACPPEVYAIMRGCWQREPQQRHSIKDV 572
>X03541-1|CAA27243.1| 641|Homo sapiens protein ( Human mRNA of trk
oncogene. ).
Length = 641
Score = 121 bits (292), Expect = 1e-26
Identities = 84/284 (29%), Positives = 124/284 (43%), Gaps = 13/284 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L +P + VAVK+L++ + A + +F EA ++ L H+HI+R
Sbjct: 339 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ-DFQREAELLTMLQHQHIVR 397
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P L++ E+ GDL R+LR A+ L +D +
Sbjct: 398 FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAK----LLAGGEDVAPGP-LGLGQLLA 452
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 453 VASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY-----YRVG 507
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
R + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S + ++ G
Sbjct: 508 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 567
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDHPRAL 868
E P CW+R A+ + PR L
Sbjct: 568 ELERPRACPPEVYAIMRGCWQREPSNATASRMCTPGCKPWPRHL 611
>L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase
protein.
Length = 1052
Score = 121 bits (292), Expect = 1e-26
Identities = 85/314 (27%), Positives = 133/314 (42%), Gaps = 34/314 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
+G G+FG VH G+ P VA+K+ + + + +FL EA+ M DH HI++ +
Sbjct: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G + + P ++ME G+LR +L+ R++ + + +
Sbjct: 488 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLI-------------------LYA 527
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
+ VHRD+ A N LV S +KLGDFG++R + + Y +
Sbjct: 528 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS------TYYKASK 581
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
G P+ WMAPES++ F+SASDVW GV M E + G +P+ V+ + +G R
Sbjct: 582 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERL 641
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL--------RDHPRALRPVLRSRVAP 878
+P CW RP E+ L +R R +
Sbjct: 642 PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATV 701
Query: 879 DADSGFGESDPPSP 892
DSG + PP P
Sbjct: 702 SWDSGGSDEAPPKP 715
>BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein.
Length = 1006
Score = 121 bits (292), Expect = 1e-26
Identities = 85/314 (27%), Positives = 133/314 (42%), Gaps = 34/314 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
+G G+FG VH G+ P VA+K+ + + + +FL EA+ M DH HI++ +
Sbjct: 428 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 487
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G + + P ++ME G+LR +L+ R++ + + +
Sbjct: 488 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLI-------------------LYA 527
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
+ VHRD+ A N LV S +KLGDFG++R + + Y +
Sbjct: 528 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS------TYYKASK 581
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
G P+ WMAPES++ F+SASDVW GV M E + G +P+ V+ + +G R
Sbjct: 582 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERL 641
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL--------RDHPRALRPVLRSRVAP 878
+P CW RP E+ L +R R +
Sbjct: 642 PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATV 701
Query: 879 DADSGFGESDPPSP 892
DSG + PP P
Sbjct: 702 SWDSGGSDEAPPKP 715
>BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein.
Length = 680
Score = 121 bits (292), Expect = 1e-26
Identities = 85/314 (27%), Positives = 133/314 (42%), Gaps = 34/314 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
+G G+FG VH G+ P VA+K+ + + + +FL EA+ M DH HI++ +
Sbjct: 56 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 115
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G + + P ++ME G+LR +L+ R++ + + +
Sbjct: 116 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLI-------------------LYA 155
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
+ VHRD+ A N LV S +KLGDFG++R + + Y +
Sbjct: 156 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS------TYYKASK 209
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
G P+ WMAPES++ F+SASDVW GV M E + G +P+ V+ + +G R
Sbjct: 210 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERL 269
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL--------RDHPRALRPVLRSRVAP 878
+P CW RP E+ L +R R +
Sbjct: 270 PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATV 329
Query: 879 DADSGFGESDPPSP 892
DSG + PP P
Sbjct: 330 SWDSGGSDEAPPKP 343
>AK094999-1|BAC04470.1| 720|Homo sapiens protein ( Homo sapiens
cDNA FLJ37680 fis, clone BRHIP2012923, highly similar to
FOCAL ADHESION KINASE 1 (EC 2.7.1.112). ).
Length = 720
Score = 121 bits (292), Expect = 1e-26
Identities = 85/314 (27%), Positives = 133/314 (42%), Gaps = 34/314 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
+G G+FG VH G+ P VA+K+ + + + +FL EA+ M DH HI++ +
Sbjct: 96 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 155
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G + + P ++ME G+LR +L+ R++ + + +
Sbjct: 156 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLI-------------------LYA 195
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
+ VHRD+ A N LV S +KLGDFG++R + + Y +
Sbjct: 196 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS------TYYKASK 249
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
G P+ WMAPES++ F+SASDVW GV M E + G +P+ V+ + +G R
Sbjct: 250 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERL 309
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL--------RDHPRALRPVLRSRVAP 878
+P CW RP E+ L +R R +
Sbjct: 310 PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATV 369
Query: 879 DADSGFGESDPPSP 892
DSG + PP P
Sbjct: 370 SWDSGGSDEAPPKP 383
>AB209083-1|BAD92320.1| 1007|Homo sapiens PTK2 protein tyrosine
kinase 2 isoform b variant protein.
Length = 1007
Score = 121 bits (292), Expect = 1e-26
Identities = 85/314 (27%), Positives = 133/314 (42%), Gaps = 34/314 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
+G G+FG VH G+ P VA+K+ + + + +FL EA+ M DH HI++ +
Sbjct: 380 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 439
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G + + P ++ME G+LR +L+ R++ + + +
Sbjct: 440 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLI-------------------LYA 479
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
+ VHRD+ A N LV S +KLGDFG++R + + Y +
Sbjct: 480 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS------TYYKASK 533
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
G P+ WMAPES++ F+SASDVW GV M E + G +P+ V+ + +G R
Sbjct: 534 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERL 593
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL--------RDHPRALRPVLRSRVAP 878
+P CW RP E+ L +R R +
Sbjct: 594 PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATV 653
Query: 879 DADSGFGESDPPSP 892
DSG + PP P
Sbjct: 654 SWDSGGSDEAPPKP 667
>AB209071-1|BAD92308.1| 975|Homo sapiens PTK2 protein tyrosine
kinase 2 isoform b variant protein.
Length = 975
Score = 121 bits (292), Expect = 1e-26
Identities = 85/314 (27%), Positives = 133/314 (42%), Gaps = 34/314 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
+G G+FG VH G+ P VA+K+ + + + +FL EA+ M DH HI++ +
Sbjct: 348 IGEGQFGDVHQGIYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLI 407
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G + + P ++ME G+LR +L+ R++ + + +
Sbjct: 408 GV-ITENPVWIIMELCTLGELRSFLQVRKYSLDLASLI-------------------LYA 447
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
+ VHRD+ A N LV S +KLGDFG++R + + Y +
Sbjct: 448 YQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDS------TYYKASK 501
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
G P+ WMAPES++ F+SASDVW GV M E + G +P+ V+ + +G R
Sbjct: 502 GKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERL 561
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL--------RDHPRALRPVLRSRVAP 878
+P CW RP E+ L +R R +
Sbjct: 562 PMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQATV 621
Query: 879 DADSGFGESDPPSP 892
DSG + PP P
Sbjct: 622 SWDSGGSDEAPPKP 635
>Z71929-1|CAA96492.1| 821|Homo sapiens FGFR2 protein.
Length = 821
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 487 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 546
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 547 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 602
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 603 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 657
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 658 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 717
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 718 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 748
>X56191-1|CAA39654.1| 769|Homo sapiens fibroblast growth factor
(FGR) receptor protein.
Length = 769
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>X52832-1|CAA37014.1| 821|Homo sapiens protein ( Human bek mRNA for
fibroblast growth factor receptor-BEK. ).
Length = 821
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 487 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 546
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 547 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 602
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 603 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 657
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 658 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 717
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 718 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 748
>M97193-1|AAA52449.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>M87771-1|AAA59471.1| 705|Homo sapiens fibroblast growth factor
receptor protein.
Length = 705
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 371 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 430
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 431 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 486
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 487 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 541
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 542 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 601
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 602 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 632
>M87770-1|AAA59470.1| 821|Homo sapiens fibroblast growth factor
receptor protein.
Length = 821
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 487 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 546
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 547 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 602
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 603 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 657
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 658 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 717
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 718 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 748
>M80634-1|AAA36147.1| 822|Homo sapiens keratinocyte growth factor
receptor protein.
Length = 822
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>M55614-1|AAA61188.1| 822|Homo sapiens TK14 protein protein.
Length = 822
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>M35718-1|AAA36152.1| 682|Homo sapiens protein ( Human
heparin-binding growth factor receptor K-sam mRNA. ).
Length = 682
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 397 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 456
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 457 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 512
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 513 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 567
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 568 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 627
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 628 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 658
>J03358-1|AAA61190.1| 822|Homo sapiens FER protein.
Length = 822
Score = 121 bits (291), Expect = 1e-26
Identities = 81/298 (27%), Positives = 130/298 (43%), Gaps = 30/298 (10%)
Query: 564 LPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAE 623
L P+ ++ ++++ ++ ++LG G FG V+ G L K VAVK+ ++
Sbjct: 547 LNPIPKD-KKWILSHEDVILGELLGKGNFGEVYKGTL----KDKTSVAVKTCKEDLPQEL 601
Query: 624 ETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDH 683
+ +FL EA I+ DH +I++ +G C + P ++ME GD +LR ++
Sbjct: 602 KIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKK-------- 653
Query: 684 LSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGD 743
+ + + +HRD+ A NCLV LK+ D
Sbjct: 654 -----------DELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISD 702
Query: 744 FGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTL 803
FGM+R+ D Y+ P+ W APE+L+ G +SS SDVWS G+L+ ET +L
Sbjct: 703 FGMSRQEDG------GVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSL 756
Query: 804 GDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
G PY + + + V G R P CW RP E+ + L
Sbjct: 757 GVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKEL 814
>DQ493927-1|ABE96832.1| 785|Homo sapiens fibroblast growth factor
receptor 2 (bacteria-expressed kinase, keratinocyte gr
protein.
Length = 785
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 485 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 544
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 545 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 600
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 601 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 655
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 656 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 715
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 716 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 746
>BC039243-1|AAH39243.2| 704|Homo sapiens FGFR2 protein protein.
Length = 704
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 370 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 429
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 430 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 485
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 486 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 540
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 541 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 600
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 601 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 631
>AF487553-1|AAM74056.1| 822|Homo sapiens fibroblast growth factor
receptor 2 protein.
Length = 822
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>AF360695-4|AAK94208.1| 766|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC3 protein.
Length = 766
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 485 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 544
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 545 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 600
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 601 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 655
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 656 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 715
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 716 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 746
>AF360695-3|AAK94209.1| 785|Homo sapiens keratinocyte growth factor
receptor 2 isoform K-sam-IIC2 protein.
Length = 785
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 485 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 544
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 545 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 600
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 601 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 655
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 656 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 715
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 716 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 746
>AF360695-2|AAK94205.1| 819|Homo sapiens keratinocyte growth factor
receptor 2 isoform BEK protein.
Length = 819
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 485 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 544
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 545 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 600
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 601 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 655
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 656 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 715
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 716 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 746
>AF360695-1|AAK94206.1| 820|Homo sapiens keratinocyte growth factor
receptor 2 isoform KGFR protein.
Length = 820
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 486 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 545
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 546 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 601
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 602 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 656
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 657 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 716
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 717 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 747
>AF125808-1|AAF19762.1| 318|Homo sapiens ETS related
protein-neurotrophic receptor tyrosine kinase fusion
protein protein.
Length = 318
Score = 121 bits (291), Expect = 1e-26
Identities = 85/294 (28%), Positives = 130/294 (44%), Gaps = 17/294 (5%)
Query: 575 LVDPAHLVTYDI-----LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEF 627
+ D H+ DI LG G FG+V L P K VAVK+L+ A + +F
Sbjct: 20 IADVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DF 78
Query: 628 LNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQD 687
EA ++ L HEHI++F G C P +++ E+ GDL ++LR A + D
Sbjct: 79 QREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAM----ILVD 134
Query: 688 SKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMA 747
+ + + + VHRD+ NCLV + +K+GDFGM+
Sbjct: 135 GQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMS 194
Query: 748 RKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRP 807
R +T Y + P+ WM PES+ F++ SDVWS GV++ E T G +P
Sbjct: 195 RDVYSTDY-----YRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQP 249
Query: 808 YGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+ S V++ ++ G E P CW+R +R E+ + L
Sbjct: 250 WFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 303
>AF097353-2|AAD31561.1| 554|Homo sapiens fibroblast growth factor
receptor 2 isoform IgIIIc isoform protein.
Length = 554
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 274 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 333
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 334 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 389
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 390 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 444
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 445 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 504
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 505 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 535
>AF097353-1|AAD31560.1| 555|Homo sapiens fibroblast growth receptor
2 IgIIIb isoform protein.
Length = 555
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 275 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 334
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 335 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 390
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 391 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 445
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 446 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 505
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 506 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 536
>AF041811-1|AAC12728.2| 408|Homo sapiens ETS related protein-growth
factor receptor tyrosine kinase fusion proteins protein.
Length = 408
Score = 121 bits (291), Expect = 1e-26
Identities = 85/294 (28%), Positives = 130/294 (44%), Gaps = 17/294 (5%)
Query: 575 LVDPAHLVTYDI-----LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEF 627
+ D H+ DI LG G FG+V L P K VAVK+L+ A + +F
Sbjct: 110 IADVQHIKRRDIVLKRELGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DF 168
Query: 628 LNEAVIMAALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQD 687
EA ++ L HEHI++F G C P +++ E+ GDL ++LR A + D
Sbjct: 169 QREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAM----ILVD 224
Query: 688 SKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMA 747
+ + + + VHRD+ NCLV + +K+GDFGM+
Sbjct: 225 GQPRQAKGELGLSQMLHIASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMS 284
Query: 748 RKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRP 807
R +T Y + P+ WM PES+ F++ SDVWS GV++ E T G +P
Sbjct: 285 RDVYSTDY-----YRVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQP 339
Query: 808 YGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+ S V++ ++ G E P CW+R +R E+ + L
Sbjct: 340 WFQLSNTEVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 393
>AB084153-1|BAC45037.1| 709|Homo sapiens isoform of FGFR2 protein.
Length = 709
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 375 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 434
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 435 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 490
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 491 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 545
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 546 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 605
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 606 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 636
>AB030078-1|BAA89301.1| 768|Homo sapiens K-sam-IIO3 protein.
Length = 768
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>AB030077-1|BAA89300.1| 817|Homo sapiens K-sam-IIO2 protein.
Length = 817
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>AB030076-1|BAA89299.1| 771|Homo sapiens K-sam-IIO1 protein.
Length = 771
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>AB030075-1|BAA89298.1| 830|Homo sapiens K-sam-IIH3 protein.
Length = 830
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>AB030074-1|BAA89297.1| 819|Homo sapiens K-sam-IIH2 protein.
Length = 819
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>AB030073-1|BAA89296.1| 819|Homo sapiens K-sam-IIH1 protein.
Length = 819
Score = 121 bits (291), Expect = 1e-26
Identities = 86/271 (31%), Positives = 121/271 (44%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHL----GVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V + G+ + K VAVK L+ A + ++ ++E +M + H++
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKN 547
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YLR RR S D E E ++
Sbjct: 548 IINLLGACTQDGPLYVIVEYASKGNLREYLRARR---PPGMEYSYDINRVPE-EQMTFKD 603
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 604 LVSCTYQLARRMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLAR--DINNID---YY 658
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVLM E TLG PY + + +
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRP 749
>Z29630-1|CAA82737.1| 612|Homo sapiens protein-tyrosine kinase
protein.
Length = 612
Score = 120 bits (290), Expect = 2e-26
Identities = 94/279 (33%), Positives = 126/279 (45%), Gaps = 27/279 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAA-PAEETEFLNEAVIMAALDHEHIIRF 645
LG+G FG V G Q+ K + VAVK L+ A PA + E L EA +M LD+ +I+R
Sbjct: 354 LGSGNFGTVKKGYYQMK-KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
+G C A+ LV ME A G L +YL++ RH +D E VS
Sbjct: 413 IGICEAESWMLV-MEMAELGPLNKYLQQNRHV--------KDKNIIELVHQVSMGMKYLE 463
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N L+ ++ K+ DFG+++ A AD Y +
Sbjct: 464 ES------------NFVHRDLAARNVLLVTQHYAKISDFGLSK---ALRAD-ENYYKAQT 507
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G +PV W APE ++ FSS SDVWS GVLM E + G +PY V + G R
Sbjct: 508 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 567
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDH 864
P G CW RP V LR++
Sbjct: 568 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 606
>X73568-1|CAA51970.1| 630|Homo sapiens protein tyrosin kinase
protein.
Length = 630
Score = 120 bits (290), Expect = 2e-26
Identities = 94/279 (33%), Positives = 126/279 (45%), Gaps = 27/279 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAA-PAEETEFLNEAVIMAALDHEHIIRF 645
LG+G FG V G Q+ K + VAVK L+ A PA + E L EA +M LD+ +I+R
Sbjct: 372 LGSGNFGTVKKGYYQMK-KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 430
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
+G C A+ LV ME A G L +YL++ RH +D E VS
Sbjct: 431 IGICEAESWMLV-MEMAELGPLNKYLQQNRHV--------KDKNIIELVHQVSMGMKYLE 481
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N L+ ++ K+ DFG+++ A AD Y +
Sbjct: 482 ES------------NFVHRDLAARNVLLVTQHYAKISDFGLSK---ALRAD-ENYYKAQT 525
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G +PV W APE ++ FSS SDVWS GVLM E + G +PY V + G R
Sbjct: 526 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 585
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDH 864
P G CW RP V LR++
Sbjct: 586 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 624
>U05012-1|AAA75374.1| 825|Homo sapiens TrkC protein.
Length = 825
Score = 120 bits (290), Expect = 2e-26
Identities = 81/277 (29%), Positives = 124/277 (44%), Gaps = 12/277 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P K VAVK+L+ A + +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DFQREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P +++ E+ GDL ++LR A + D + + +
Sbjct: 603 FYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPNAM----ILVDGQPRQAKGELGLSQMLH 658
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV + +K+GDFGM+R +T Y
Sbjct: 659 IASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDY-----YRVG 713
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWS GV++ E T G +P+ S V++ ++ G
Sbjct: 714 GHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTEVIECITQGR 773
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
E P CW+R +R E+ + L
Sbjct: 774 VLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 810
>L28824-1|AAA36526.1| 635|Homo sapiens protein tyrosine kinase
protein.
Length = 635
Score = 120 bits (290), Expect = 2e-26
Identities = 94/279 (33%), Positives = 126/279 (45%), Gaps = 27/279 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAA-PAEETEFLNEAVIMAALDHEHIIRF 645
LG+G FG V G Q+ K + VAVK L+ A PA + E L EA +M LD+ +I+R
Sbjct: 377 LGSGNFGTVKKGYYQMK-KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
+G C A+ LV ME A G L +YL++ RH +D E VS
Sbjct: 436 IGICEAESWMLV-MEMAELGPLNKYLQQNRHV--------KDKNIIELVHQVSMGMKYLE 486
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N L+ ++ K+ DFG+++ A AD Y +
Sbjct: 487 ES------------NFVHRDLAARNVLLVTQHYAKISDFGLSK---ALRAD-ENYYKAQT 530
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G +PV W APE ++ FSS SDVWS GVLM E + G +PY V + G R
Sbjct: 531 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 590
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDH 864
P G CW RP V LR++
Sbjct: 591 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 629
>BC011399-1|AAH11399.1| 612|Homo sapiens SYK protein protein.
Length = 612
Score = 120 bits (290), Expect = 2e-26
Identities = 94/279 (33%), Positives = 126/279 (45%), Gaps = 27/279 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAA-PAEETEFLNEAVIMAALDHEHIIRF 645
LG+G FG V G Q+ K + VAVK L+ A PA + E L EA +M LD+ +I+R
Sbjct: 354 LGSGNFGTVKKGYYQMK-KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
+G C A+ LV ME A G L +YL++ RH +D E VS
Sbjct: 413 IGICEAESWMLV-MEMAELGPLNKYLQQNRHV--------KDKNIIELVHQVSMGMKYLE 463
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N L+ ++ K+ DFG+++ A AD Y +
Sbjct: 464 ES------------NFVHRDLAARNVLLVTQHYAKISDFGLSK---ALRAD-ENYYKAQT 507
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G +PV W APE ++ FSS SDVWS GVLM E + G +PY V + G R
Sbjct: 508 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 567
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDH 864
P G CW RP V LR++
Sbjct: 568 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 606
>BC002962-1|AAH02962.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 120 bits (290), Expect = 2e-26
Identities = 94/279 (33%), Positives = 126/279 (45%), Gaps = 27/279 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAA-PAEETEFLNEAVIMAALDHEHIIRF 645
LG+G FG V G Q+ K + VAVK L+ A PA + E L EA +M LD+ +I+R
Sbjct: 377 LGSGNFGTVKKGYYQMK-KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
+G C A+ LV ME A G L +YL++ RH +D E VS
Sbjct: 436 IGICEAESWMLV-MEMAELGPLNKYLQQNRHV--------KDKNIIELVHQVSMGMKYLE 486
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N L+ ++ K+ DFG+++ A AD Y +
Sbjct: 487 ES------------NFVHRDLAARNVLLVTQHYAKISDFGLSK---ALRAD-ENYYKAQT 530
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G +PV W APE ++ FSS SDVWS GVLM E + G +PY V + G R
Sbjct: 531 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 590
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDH 864
P G CW RP V LR++
Sbjct: 591 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 629
>BC001645-1|AAH01645.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 120 bits (290), Expect = 2e-26
Identities = 94/279 (33%), Positives = 126/279 (45%), Gaps = 27/279 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAA-PAEETEFLNEAVIMAALDHEHIIRF 645
LG+G FG V G Q+ K + VAVK L+ A PA + E L EA +M LD+ +I+R
Sbjct: 377 LGSGNFGTVKKGYYQMK-KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
+G C A+ LV ME A G L +YL++ RH +D E VS
Sbjct: 436 IGICEAESWMLV-MEMAELGPLNKYLQQNRHV--------KDKNIIELVHQVSMGMKYLE 486
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N L+ ++ K+ DFG+++ A AD Y +
Sbjct: 487 ES------------NFVHRDLAARNVLLVTQHYAKISDFGLSK---ALRAD-ENYYKAQT 530
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G +PV W APE ++ FSS SDVWS GVLM E + G +PY V + G R
Sbjct: 531 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 590
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDH 864
P G CW RP V LR++
Sbjct: 591 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 629
>AL354862-3|CAI16875.1| 612|Homo sapiens spleen tyrosine kinase
protein.
Length = 612
Score = 120 bits (290), Expect = 2e-26
Identities = 94/279 (33%), Positives = 126/279 (45%), Gaps = 27/279 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAA-PAEETEFLNEAVIMAALDHEHIIRF 645
LG+G FG V G Q+ K + VAVK L+ A PA + E L EA +M LD+ +I+R
Sbjct: 354 LGSGNFGTVKKGYYQMK-KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 412
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
+G C A+ LV ME A G L +YL++ RH +D E VS
Sbjct: 413 IGICEAESWMLV-MEMAELGPLNKYLQQNRHV--------KDKNIIELVHQVSMGMKYLE 463
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N L+ ++ K+ DFG+++ A AD Y +
Sbjct: 464 ES------------NFVHRDLAARNVLLVTQHYAKISDFGLSK---ALRAD-ENYYKAQT 507
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G +PV W APE ++ FSS SDVWS GVLM E + G +PY V + G R
Sbjct: 508 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 567
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDH 864
P G CW RP V LR++
Sbjct: 568 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 606
>AL354862-2|CAI16876.1| 635|Homo sapiens spleen tyrosine kinase
protein.
Length = 635
Score = 120 bits (290), Expect = 2e-26
Identities = 94/279 (33%), Positives = 126/279 (45%), Gaps = 27/279 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAA-PAEETEFLNEAVIMAALDHEHIIRF 645
LG+G FG V G Q+ K + VAVK L+ A PA + E L EA +M LD+ +I+R
Sbjct: 377 LGSGNFGTVKKGYYQMK-KVVKTVAVKILKNEANDPALKDELLAEANVMQQLDNPYIVRM 435
Query: 646 VGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXX 705
+G C A+ LV ME A G L +YL++ RH +D E VS
Sbjct: 436 IGICEAESWMLV-MEMAELGPLNKYLQQNRHV--------KDKNIIELVHQVSMGMKYLE 486
Query: 706 XXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRR 765
VHRD+ A N L+ ++ K+ DFG+++ A AD Y +
Sbjct: 487 ES------------NFVHRDLAARNVLLVTQHYAKISDFGLSK---ALRAD-ENYYKAQT 530
Query: 766 RGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGR 825
G +PV W APE ++ FSS SDVWS GVLM E + G +PY V + G R
Sbjct: 531 HGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGER 590
Query: 826 PELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRDH 864
P G CW RP V LR++
Sbjct: 591 MGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNY 629
>X60957-1|CAA43290.1| 1138|Homo sapiens receptor tyrosine kinase
protein.
Length = 1138
Score = 120 bits (289), Expect = 2e-26
Identities = 84/306 (27%), Positives = 142/306 (46%), Gaps = 16/306 (5%)
Query: 557 SVIRPAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLR 616
++ R KL P + L+ +++ + D++G G FG+V +++ G A+K L+
Sbjct: 817 TLTRRPKLQP--EPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMN-AAIKMLK 873
Query: 617 KGAAPAEETEFLNEAVIMAALDHE-HIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR 675
+ A+ + +F E ++ L H +II +GAC +G + +E+A +G+L +LR+ R
Sbjct: 874 EYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSR 933
Query: 676 HFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDS 735
++D +++ + +S + +HRD+ A N LV
Sbjct: 934 VL--ETDPAF--AREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGE 989
Query: 736 RRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGV 795
K+ DFG++R G Y + G PV WMA ESL+ +++ SDVWS GV
Sbjct: 990 NLASKIADFGLSR--------GEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGV 1041
Query: 796 LMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAG 855
L+ E V+LG PY + + + + G R E P CWR ERP
Sbjct: 1042 LLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFA 1101
Query: 856 EVARYL 861
++A L
Sbjct: 1102 QIALQL 1107
>M64347-1|AAA58470.1| 731|Homo sapiens fgflr protein.
Length = 731
Score = 120 bits (289), Expect = 2e-26
Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRV----HLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V +G+ + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 403 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 462
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP VL+E+A G+LR +LR RR D+ K EE ++
Sbjct: 463 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARR--PPGLDYSFDTCKPPEEQ--LTFKD 518
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 519 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR--DVHNLD---YY 573
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 574 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK 633
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW A +RP
Sbjct: 634 EGHRMDKPANCTHDLYMIMRECWHAAPSQRP 664
>M58051-1|AAA52450.1| 806|Homo sapiens fibroblast growth factor
receptor protein.
Length = 806
Score = 120 bits (289), Expect = 2e-26
Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRV----HLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V +G+ + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 478 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 537
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP VL+E+A G+LR +LR RR D+ K EE ++
Sbjct: 538 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARR--PPGLDYSFDTCKPPEEQ--LTFKD 593
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 594 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR--DVHNLD---YY 648
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 649 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK 708
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW A +RP
Sbjct: 709 EGHRMDKPANCTHDLYMIMRECWHAAPSQRP 739
>BC128610-1|AAI28611.1| 480|Homo sapiens FGFR3 protein protein.
Length = 480
Score = 120 bits (289), Expect = 2e-26
Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRV----HLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V +G+ + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 152 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 211
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP VL+E+A G+LR +LR RR D+ K EE ++
Sbjct: 212 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARR--PPGLDYSFDTCKPPEEQ--LTFKD 267
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 268 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR--DVHNLD---YY 322
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 323 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK 382
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW A +RP
Sbjct: 383 EGHRMDKPANCTHDLYMIMRECWHAAPSQRP 413
>BC121175-1|AAI21176.1| 480|Homo sapiens FGFR3 protein protein.
Length = 480
Score = 120 bits (289), Expect = 2e-26
Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRV----HLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V +G+ + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 152 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 211
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP VL+E+A G+LR +LR RR D+ K EE ++
Sbjct: 212 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARR--PPGLDYSFDTCKPPEEQ--LTFKD 267
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 268 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR--DVHNLD---YY 322
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 323 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK 382
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW A +RP
Sbjct: 383 EGHRMDKPANCTHDLYMIMRECWHAAPSQRP 413
>BC038239-1|AAH38239.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 120 bits (289), Expect = 2e-26
Identities = 84/306 (27%), Positives = 142/306 (46%), Gaps = 16/306 (5%)
Query: 557 SVIRPAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLR 616
++ R KL P + L+ +++ + D++G G FG+V +++ G A+K L+
Sbjct: 817 TLTRRPKLQP--EPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMN-AAIKMLK 873
Query: 617 KGAAPAEETEFLNEAVIMAALDHE-HIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR 675
+ A+ + +F E ++ L H +II +GAC +G + +E+A +G+L +LR+ R
Sbjct: 874 EYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSR 933
Query: 676 HFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDS 735
++D +++ + +S + +HRD+ A N LV
Sbjct: 934 VL--ETDPAF--AREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGE 989
Query: 736 RRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGV 795
K+ DFG++R G Y + G PV WMA ESL+ +++ SDVWS GV
Sbjct: 990 NLASKIADFGLSR--------GEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGV 1041
Query: 796 LMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAG 855
L+ E V+LG PY + + + + G R E P CWR ERP
Sbjct: 1042 LLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFA 1101
Query: 856 EVARYL 861
++A L
Sbjct: 1102 QIALQL 1107
>AY768549-1|AAU89726.1| 806|Homo sapiens fibroblast growth factor
receptor 3 (achondroplasia, thanatophoric dwarfism)
protein.
Length = 806
Score = 120 bits (289), Expect = 2e-26
Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRV----HLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V +G+ + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 478 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 537
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP VL+E+A G+LR +LR RR D+ K EE ++
Sbjct: 538 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARR--PPGLDYSFDTCKPPEEQ--LTFKD 593
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 594 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR--DVHNLD---YY 648
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 649 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK 708
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW A +RP
Sbjct: 709 EGHRMDKPANCTHDLYMIMRECWHAAPSQRP 739
>AL139289-10|CAI23385.1| 1138|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 1138
Score = 120 bits (289), Expect = 2e-26
Identities = 84/306 (27%), Positives = 142/306 (46%), Gaps = 16/306 (5%)
Query: 557 SVIRPAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLR 616
++ R KL P + L+ +++ + D++G G FG+V +++ G A+K L+
Sbjct: 817 TLTRRPKLQP--EPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMN-AAIKMLK 873
Query: 617 KGAAPAEETEFLNEAVIMAALDHE-HIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR 675
+ A+ + +F E ++ L H +II +GAC +G + +E+A +G+L +LR+ R
Sbjct: 874 EYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSR 933
Query: 676 HFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDS 735
++D +++ + +S + +HRD+ A N LV
Sbjct: 934 VL--ETDPAF--AREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGE 989
Query: 736 RRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGV 795
K+ DFG++R G Y + G PV WMA ESL+ +++ SDVWS GV
Sbjct: 990 NLASKIADFGLSR--------GEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGV 1041
Query: 796 LMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAG 855
L+ E V+LG PY + + + + G R E P CWR ERP
Sbjct: 1042 LLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFA 1101
Query: 856 EVARYL 861
++A L
Sbjct: 1102 QIALQL 1107
>AL139289-9|CAI23386.1| 541|Homo sapiens tyrosine kinase with
immunoglobulin-like and EGF-like domains 1 protein.
Length = 541
Score = 120 bits (289), Expect = 2e-26
Identities = 84/306 (27%), Positives = 142/306 (46%), Gaps = 16/306 (5%)
Query: 557 SVIRPAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLR 616
++ R KL P + L+ +++ + D++G G FG+V +++ G A+K L+
Sbjct: 220 TLTRRPKLQP--EPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMN-AAIKMLK 276
Query: 617 KGAAPAEETEFLNEAVIMAALDHE-HIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR 675
+ A+ + +F E ++ L H +II +GAC +G + +E+A +G+L +LR+ R
Sbjct: 277 EYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSR 336
Query: 676 HFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDS 735
++D +++ + +S + +HRD+ A N LV
Sbjct: 337 VL--ETDPAF--AREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGE 392
Query: 736 RRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGV 795
K+ DFG++R G Y + G PV WMA ESL+ +++ SDVWS GV
Sbjct: 393 NLASKIADFGLSR--------GEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGV 444
Query: 796 LMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAG 855
L+ E V+LG PY + + + + G R E P CWR ERP
Sbjct: 445 LLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFA 504
Query: 856 EVARYL 861
++A L
Sbjct: 505 QIALQL 510
>AF487554-2|AAM22078.1| 769|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 769
Score = 120 bits (289), Expect = 2e-26
Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRV----HLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V +G+ + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 441 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 500
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP VL+E+A G+LR +LR RR D+ K EE ++
Sbjct: 501 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARR--PPGLDYSFDTCKPPEEQ--LTFKD 556
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 557 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR--DVHNLD---YY 611
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 612 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK 671
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW A +RP
Sbjct: 672 EGHRMDKPANCTHDLYMIMRECWHAAPSQRP 702
>AF487554-1|AAM22079.1| 771|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 771
Score = 120 bits (289), Expect = 2e-26
Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRV----HLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V +G+ + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 443 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 502
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP VL+E+A G+LR +LR RR D+ K EE ++
Sbjct: 503 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARR--PPGLDYSFDTCKPPEEQ--LTFKD 558
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 559 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR--DVHNLD---YY 613
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 614 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK 673
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW A +RP
Sbjct: 674 EGHRMDKPANCTHDLYMIMRECWHAAPSQRP 704
>AF245114-1|AAF63380.1| 694|Homo sapiens fibroblast growth factor
receptor 3 protein.
Length = 694
Score = 120 bits (289), Expect = 2e-26
Identities = 86/271 (31%), Positives = 123/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRV----HLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V +G+ + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 366 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 425
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP VL+E+A G+LR +LR RR D+ K EE ++
Sbjct: 426 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARR--PPGLDYSFDTCKPPEEQ--LTFKD 481
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 482 LVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLAR--DVHNLD---YY 536
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 537 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLK 596
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW A +RP
Sbjct: 597 EGHRMDKPANCTHDLYMIMRECWHAAPSQRP 627
>AF217976-1|AAG17219.1| 421|Homo sapiens unknown protein.
Length = 421
Score = 120 bits (289), Expect = 2e-26
Identities = 84/306 (27%), Positives = 142/306 (46%), Gaps = 16/306 (5%)
Query: 557 SVIRPAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLR 616
++ R KL P + L+ +++ + D++G G FG+V +++ G A+K L+
Sbjct: 100 TLTRRPKLQP--EPLSYPVLEWEDITFEDLIGEGNFGQVIRAMIKKDGLKMN-AAIKMLK 156
Query: 617 KGAAPAEETEFLNEAVIMAALDHE-HIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR 675
+ A+ + +F E ++ L H +II +GAC +G + +E+A +G+L +LR+ R
Sbjct: 157 EYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSR 216
Query: 676 HFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDS 735
++D +++ + +S + +HRD+ A N LV
Sbjct: 217 VL--ETDPAF--AREHGTASTLSSRQLLRFASDAANGMQYLSEKQFIHRDLAARNVLVGE 272
Query: 736 RRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGV 795
K+ DFG++R G Y + G PV WMA ESL+ +++ SDVWS GV
Sbjct: 273 NLASKIADFGLSR--------GEEVYVKKTMGRLPVRWMAIESLNYSVYTTKSDVWSFGV 324
Query: 796 LMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAG 855
L+ E V+LG PY + + + + G R E P CWR ERP
Sbjct: 325 LLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRDRPYERPPFA 384
Query: 856 EVARYL 861
++A L
Sbjct: 385 QIALQL 390
>X06704-1|CAA29888.1| 439|Homo sapiens protein ( Human mRNA for
trk-2h oncogene. ).
Length = 439
Score = 119 bits (286), Expect = 5e-26
Identities = 81/273 (29%), Positives = 121/273 (44%), Gaps = 13/273 (4%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L +P + VAVK+L++ + A + +F EA ++ L H+HI+R
Sbjct: 159 LGEGAFGKVFLAECHNLLPEQDKMLVAVKALKEASESARQ-DFQREAELLTMLQHQHIVR 217
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P L++ E+ GDL R+LR A+ L +D +
Sbjct: 218 FFGVCTEGRPLLMVFEYMRHGDLNRFLRSHGPDAK----LLAGGEDVAPGP-LGLGQLLA 272
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 273 VASQVAAGMVYLAGLHFVHRDLATRNCLVGQGLVVKIGDFGMSRDIYSTDY-----YRVG 327
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
R + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S + ++ G
Sbjct: 328 GRTMLPIRWMPPESILYRKFTTESDVWSFGVVLWEIFTYGKQPWYQLSNTEAIDCITQGR 387
Query: 825 RPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P CW +R + +V
Sbjct: 388 ELERPRACPPEVYAIMRGCWHGEPQQRHSIKDV 420
>BC053878-1|AAH53878.1| 619|Homo sapiens zeta-chain (TCR)
associated protein kinase 70kDa protein.
Length = 619
Score = 118 bits (285), Expect = 7e-26
Identities = 88/274 (32%), Positives = 125/274 (45%), Gaps = 26/274 (9%)
Query: 580 HLVTYDI-LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD 638
+L+ DI LG G FG V GV ++ K VA+K L++G A+ E + EA IM LD
Sbjct: 336 NLLIADIELGCGNFGSVRQGVYRMR-KKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLD 394
Query: 639 HEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVS 698
+ +I+R +G C A+ LV ME A G L ++L +R E +
Sbjct: 395 NPYIVRLIGVCQAEALMLV-MEMAGGGPLHKFLVGKR-------------------EEIP 434
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
+ VHRD+ A N L+ +R K+ DFG+++ A GAD +
Sbjct: 435 VSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSK---ALGADDS 491
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y R G +P+ W APE ++ FSS SDVWS GV M E ++ G +PY V+
Sbjct: 492 Y-YTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMA 550
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+ G R E P CW +RP
Sbjct: 551 FIEQGKRMECPPECPPELYALMSDCWIYKWEDRP 584
>BC039039-1|AAH39039.1| 493|Homo sapiens ZAP70 protein protein.
Length = 493
Score = 118 bits (285), Expect = 7e-26
Identities = 88/274 (32%), Positives = 125/274 (45%), Gaps = 26/274 (9%)
Query: 580 HLVTYDI-LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD 638
+L+ DI LG G FG V GV ++ K VA+K L++G A+ E + EA IM LD
Sbjct: 210 NLLIADIELGCGNFGSVRQGVYRMR-KKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLD 268
Query: 639 HEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVS 698
+ +I+R +G C A+ LV ME A G L ++L +R E +
Sbjct: 269 NPYIVRLIGVCQAEALMLV-MEMAGGGPLHKFLVGKR-------------------EEIP 308
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
+ VHRD+ A N L+ +R K+ DFG+++ A GAD +
Sbjct: 309 VSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSK---ALGADDS 365
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y R G +P+ W APE ++ FSS SDVWS GV M E ++ G +PY V+
Sbjct: 366 Y-YTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMA 424
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+ G R E P CW +RP
Sbjct: 425 FIEQGKRMECPPECPPELYALMSDCWIYKWEDRP 458
>AM051276-1|CAJ19682.1| 319|Homo sapiens dominant-negative
kinase-deficient Brutons tyrosine kinase isoform 2
protein.
Length = 319
Score = 118 bits (285), Expect = 7e-26
Identities = 83/251 (33%), Positives = 121/251 (48%), Gaps = 33/251 (13%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+DP L LGTG+FG V G + VA+K +++G+ E EF+ EA +M
Sbjct: 68 IDPKDLTFLKELGTGQFGVVKYG----KWRGQYDVAIKMIKEGSM--SEDEFIEEAKVMM 121
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDF-EES 694
L HE +++ G C + P ++ E+ G L YLRE RH Q+ L + KD E
Sbjct: 122 NLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNYLREMRH-RFQTQQLLEMCKDVCEAM 180
Query: 695 EHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATG 754
E++ + +HRD+ A NCLV+ + +K+ DFG++R
Sbjct: 181 EYLES-------------------KQFLHRDLAARNCLVNDQGVVKVSDFGLSRYV---- 217
Query: 755 ADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPL 814
D EY FPV W PE L FSS SD+W+ GVLM E +LG PY ++
Sbjct: 218 LDD--EYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNS 275
Query: 815 RVLQHVSSGGR 825
+H++ G R
Sbjct: 276 ETAEHIAQGLR 286
>AC016699-1|AAX93187.1| 493|Homo sapiens unknown protein.
Length = 493
Score = 118 bits (285), Expect = 7e-26
Identities = 88/274 (32%), Positives = 125/274 (45%), Gaps = 26/274 (9%)
Query: 580 HLVTYDI-LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD 638
+L+ DI LG G FG V GV ++ K VA+K L++G A+ E + EA IM LD
Sbjct: 210 NLLIADIELGCGNFGSVRQGVYRMR-KKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLD 268
Query: 639 HEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVS 698
+ +I+R +G C A+ LV ME A G L ++L +R E +
Sbjct: 269 NPYIVRLIGVCQAEALMLV-MEMAGGGPLHKFLVGKR-------------------EEIP 308
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
+ VHRD+ A N L+ +R K+ DFG+++ A GAD +
Sbjct: 309 VSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSK---ALGADDS 365
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y R G +P+ W APE ++ FSS SDVWS GV M E ++ G +PY V+
Sbjct: 366 Y-YTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMA 424
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+ G R E P CW +RP
Sbjct: 425 FIEQGKRMECPPECPPELYALMSDCWIYKWEDRP 458
>AB083211-1|BAC43747.1| 312|Homo sapiens truncated ZAP kinase
protein.
Length = 312
Score = 118 bits (285), Expect = 7e-26
Identities = 88/274 (32%), Positives = 125/274 (45%), Gaps = 26/274 (9%)
Query: 580 HLVTYDI-LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALD 638
+L+ DI LG G FG V GV ++ K VA+K L++G A+ E + EA IM LD
Sbjct: 29 NLLIADIELGCGNFGSVRQGVYRMR-KKQIDVAIKVLKQGTEKADTEEMMREAQIMHQLD 87
Query: 639 HEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVS 698
+ +I+R +G C A+ LV ME A G L ++L +R E +
Sbjct: 88 NPYIVRLIGVCQAEALMLV-MEMAGGGPLHKFLVGKR-------------------EEIP 127
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
+ VHRD+ A N L+ +R K+ DFG+++ A GAD +
Sbjct: 128 VSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGLSK---ALGADDS 184
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y R G +P+ W APE ++ FSS SDVWS GV M E ++ G +PY V+
Sbjct: 185 Y-YTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEALSYGQKPYKKMKGPEVMA 243
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
+ G R E P CW +RP
Sbjct: 244 FIEQGKRMECPPECPPELYALMSDCWIYKWEDRP 277
>L36645-1|AAA74246.1| 986|Homo sapiens receptor protein-tyrosine
kinase protein.
Length = 986
Score = 118 bits (284), Expect = 9e-26
Identities = 83/286 (29%), Positives = 130/286 (45%), Gaps = 23/286 (8%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + ++G G FG V G L+VPGK VA+K+L+ G + +FL+EA IM
Sbjct: 616 IDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMG 675
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +II G P +++ E+ G L +LR+ D + F +
Sbjct: 676 QFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRK------------NDGR-FTVIQ 722
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V R + R++ ++ LV K+ DFGM+R +
Sbjct: 723 LVG-MLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLV-----CKVSDFGMSRVLE---D 773
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D A Y R G P+ W APE+++ F+SASDVWS G++M E ++ G+RPY S
Sbjct: 774 DPEAAYT-TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 832
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
V++ + G R P CW++ +RP G++ L
Sbjct: 833 VIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNML 878
>BC105002-1|AAI05003.1| 986|Homo sapiens ephrin receptor EphA4
protein.
Length = 986
Score = 118 bits (284), Expect = 9e-26
Identities = 83/286 (29%), Positives = 130/286 (45%), Gaps = 23/286 (8%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + ++G G FG V G L+VPGK VA+K+L+ G + +FL+EA IM
Sbjct: 616 IDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMG 675
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +II G P +++ E+ G L +LR+ D + F +
Sbjct: 676 QFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRK------------NDGR-FTVIQ 722
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V R + R++ ++ LV K+ DFGM+R +
Sbjct: 723 LVG-MLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLV-----CKVSDFGMSRVLE---D 773
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D A Y R G P+ W APE+++ F+SASDVWS G++M E ++ G+RPY S
Sbjct: 774 DPEAAYT-TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 832
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
V++ + G R P CW++ +RP G++ L
Sbjct: 833 VIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNML 878
>BC105000-1|AAI05001.1| 986|Homo sapiens EPH receptor A4 protein.
Length = 986
Score = 118 bits (284), Expect = 9e-26
Identities = 83/286 (29%), Positives = 130/286 (45%), Gaps = 23/286 (8%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + ++G G FG V G L+VPGK VA+K+L+ G + +FL+EA IM
Sbjct: 616 IDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMG 675
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +II G P +++ E+ G L +LR+ D + F +
Sbjct: 676 QFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRK------------NDGR-FTVIQ 722
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V R + R++ ++ LV K+ DFGM+R +
Sbjct: 723 LVG-MLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLV-----CKVSDFGMSRVLE---D 773
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D A Y R G P+ W APE+++ F+SASDVWS G++M E ++ G+RPY S
Sbjct: 774 DPEAAYT-TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 832
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
V++ + G R P CW++ +RP G++ L
Sbjct: 833 VIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNML 878
>BC026327-1|AAH26327.1| 949|Homo sapiens EPHA4 protein protein.
Length = 949
Score = 118 bits (284), Expect = 9e-26
Identities = 83/286 (29%), Positives = 130/286 (45%), Gaps = 23/286 (8%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + ++G G FG V G L+VPGK VA+K+L+ G + +FL+EA IM
Sbjct: 616 IDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMG 675
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +II G P +++ E+ G L +LR+ D + F +
Sbjct: 676 QFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRK------------NDGR-FTVIQ 722
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V R + R++ ++ LV K+ DFGM+R +
Sbjct: 723 LVG-MLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLV-----CKVSDFGMSRVLE---D 773
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D A Y R G P+ W APE+++ F+SASDVWS G++M E ++ G+RPY S
Sbjct: 774 DPEAAYT-TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 832
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
V++ + G R P CW++ +RP G++ L
Sbjct: 833 VIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNML 878
>AC010899-2|AAY24284.1| 711|Homo sapiens unknown protein.
Length = 711
Score = 118 bits (284), Expect = 9e-26
Identities = 83/286 (29%), Positives = 130/286 (45%), Gaps = 23/286 (8%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
+D + + ++G G FG V G L+VPGK VA+K+L+ G + +FL+EA IM
Sbjct: 341 IDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYTDKQRRDFLSEASIMG 400
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
DH +II G P +++ E+ G L +LR+ D + F +
Sbjct: 401 QFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRK------------NDGR-FTVIQ 447
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
V R + R++ ++ LV K+ DFGM+R +
Sbjct: 448 LVG-MLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLV-----CKVSDFGMSRVLE---D 498
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D A Y R G P+ W APE+++ F+SASDVWS G++M E ++ G+RPY S
Sbjct: 499 DPEAAYT-TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQD 557
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
V++ + G R P CW++ +RP G++ L
Sbjct: 558 VIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNML 603
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 117 bits (282), Expect = 2e-25
Identities = 83/280 (29%), Positives = 132/280 (47%), Gaps = 21/280 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG FG V L Q G A V VKSL+ ++ +F E + L+H +++R
Sbjct: 802 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELEMFGKLNHANVVR 860
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G C P +++E+ GDL+++LR + S+D K +S+ +S
Sbjct: 861 LLGLCREAEPHYMVLEYVDLGDLKQFLRISK---------SKDEK--LKSQPLSTKQKVA 909
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VH+D+ A NCLV ++R++K+ G+++ D + EY
Sbjct: 910 LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSK--DVYNS----EYYHF 963
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG- 823
R+ P+ WM+PE++ G FS+ SDVW+ GVLM E T G+ P+G + VL + +G
Sbjct: 964 RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGK 1023
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
R P G CW + +RP+ E+A L D
Sbjct: 1024 ARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGD 1063
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 117 bits (282), Expect = 2e-25
Identities = 79/283 (27%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 587 LGTGRFGRVHLGVLQVPGKAP-RP---VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHI 642
+G G FGRV + PG P P VAVK L++ A+ + +F EA +MA D+ +I
Sbjct: 485 IGEGAFGRVFQA--RAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNI 542
Query: 643 IRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HFAEQSDHLSQDSKDFEESEH---VS 698
++ +G C P +L E+ +GDL +LR H H + S +S
Sbjct: 543 VKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS 602
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
R VHRD+ NCLV +K+ DFG++R + A
Sbjct: 603 CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYS-----A 657
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y P+ WM PES+ +++ SDVW+ GV++ E + G +PY + V+
Sbjct: 658 DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIY 717
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+V G P CW + +RP+ + R L
Sbjct: 718 YVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 760
>BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein.
Length = 783
Score = 117 bits (282), Expect = 2e-25
Identities = 79/283 (27%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 587 LGTGRFGRVHLGVLQVPGKAP-RP---VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHI 642
+G G FGRV + PG P P VAVK L++ A+ + +F EA +MA D+ +I
Sbjct: 495 IGEGAFGRVFQA--RAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNI 552
Query: 643 IRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HFAEQSDHLSQDSKDFEESEH---VS 698
++ +G C P +L E+ +GDL +LR H H + S +S
Sbjct: 553 VKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS 612
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
R VHRD+ NCLV +K+ DFG++R + A
Sbjct: 613 CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYS-----A 667
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y P+ WM PES+ +++ SDVW+ GV++ E + G +PY + V+
Sbjct: 668 DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIY 727
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+V G P CW + +RP+ + R L
Sbjct: 728 YVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 770
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 117 bits (282), Expect = 2e-25
Identities = 83/280 (29%), Positives = 132/280 (47%), Gaps = 21/280 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG FG V L Q G A V VKSL+ ++ +F E + L+H +++R
Sbjct: 802 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELEMFGKLNHANVVR 860
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G C P +++E+ GDL+++LR + S+D K +S+ +S
Sbjct: 861 LLGLCREAEPHYMVLEYVDLGDLKQFLRISK---------SKDEK--LKSQPLSTKQKVA 909
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VH+D+ A NCLV ++R++K+ G+++ D + EY
Sbjct: 910 LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSK--DVYNS----EYYHF 963
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG- 823
R+ P+ WM+PE++ G FS+ SDVW+ GVLM E T G+ P+G + VL + +G
Sbjct: 964 RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGK 1023
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
R P G CW + +RP+ E+A L D
Sbjct: 1024 ARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGD 1063
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 117 bits (282), Expect = 2e-25
Identities = 79/283 (27%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 587 LGTGRFGRVHLGVLQVPGKAP-RP---VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHI 642
+G G FGRV + PG P P VAVK L++ A+ + +F EA +MA D+ +I
Sbjct: 579 IGEGAFGRVFQA--RAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNI 636
Query: 643 IRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HFAEQSDHLSQDSKDFEESEH---VS 698
++ +G C P +L E+ +GDL +LR H H + S +S
Sbjct: 637 VKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS 696
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
R VHRD+ NCLV +K+ DFG++R + A
Sbjct: 697 CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYS-----A 751
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y P+ WM PES+ +++ SDVW+ GV++ E + G +PY + V+
Sbjct: 752 DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIY 811
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+V G P CW + +RP+ + R L
Sbjct: 812 YVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 854
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 117 bits (282), Expect = 2e-25
Identities = 79/283 (27%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 587 LGTGRFGRVHLGVLQVPGKAP-RP---VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHI 642
+G G FGRV + PG P P VAVK L++ A+ + +F EA +MA D+ +I
Sbjct: 587 IGEGAFGRVFQA--RAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNI 644
Query: 643 IRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HFAEQSDHLSQDSKDFEESEH---VS 698
++ +G C P +L E+ +GDL +LR H H + S +S
Sbjct: 645 VKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS 704
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
R VHRD+ NCLV +K+ DFG++R + A
Sbjct: 705 CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYS-----A 759
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y P+ WM PES+ +++ SDVW+ GV++ E + G +PY + V+
Sbjct: 760 DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIY 819
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+V G P CW + +RP+ + R L
Sbjct: 820 YVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 862
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine kinase
7 protein.
Length = 1070
Score = 117 bits (282), Expect = 2e-25
Identities = 83/280 (29%), Positives = 132/280 (47%), Gaps = 21/280 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG FG V L Q G A V VKSL+ ++ +F E + L+H +++R
Sbjct: 802 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELEMFGKLNHANVVR 860
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G C P +++E+ GDL+++LR + S+D K +S+ +S
Sbjct: 861 LLGLCREAEPHYMVLEYVDLGDLKQFLRISK---------SKDEK--LKSQPLSTKQKVA 909
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VH+D+ A NCLV ++R++K+ G+++ D + EY
Sbjct: 910 LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSK--DVYNS----EYYHF 963
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG- 823
R+ P+ WM+PE++ G FS+ SDVW+ GVLM E T G+ P+G + VL + +G
Sbjct: 964 RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGK 1023
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
R P G CW + +RP+ E+A L D
Sbjct: 1024 ARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGD 1063
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 117 bits (282), Expect = 2e-25
Identities = 79/283 (27%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 587 LGTGRFGRVHLGVLQVPGKAP-RP---VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHI 642
+G G FGRV + PG P P VAVK L++ A+ + +F EA +MA D+ +I
Sbjct: 579 IGEGAFGRVFQA--RAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNI 636
Query: 643 IRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HFAEQSDHLSQDSKDFEESEH---VS 698
++ +G C P +L E+ +GDL +LR H H + S +S
Sbjct: 637 VKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS 696
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
R VHRD+ NCLV +K+ DFG++R + A
Sbjct: 697 CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYS-----A 751
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y P+ WM PES+ +++ SDVW+ GV++ E + G +PY + V+
Sbjct: 752 DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIY 811
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+V G P CW + +RP+ + R L
Sbjct: 812 YVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 854
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 117 bits (282), Expect = 2e-25
Identities = 79/283 (27%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 587 LGTGRFGRVHLGVLQVPGKAP-RP---VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHI 642
+G G FGRV + PG P P VAVK L++ A+ + +F EA +MA D+ +I
Sbjct: 587 IGEGAFGRVFQA--RAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNI 644
Query: 643 IRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HFAEQSDHLSQDSKDFEESEH---VS 698
++ +G C P +L E+ +GDL +LR H H + S +S
Sbjct: 645 VKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS 704
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
R VHRD+ NCLV +K+ DFG++R + A
Sbjct: 705 CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYS-----A 759
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y P+ WM PES+ +++ SDVW+ GV++ E + G +PY + V+
Sbjct: 760 DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIY 819
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+V G P CW + +RP+ + R L
Sbjct: 820 YVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 862
>AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor
precursor PTK7-4 protein.
Length = 1014
Score = 117 bits (282), Expect = 2e-25
Identities = 83/280 (29%), Positives = 132/280 (47%), Gaps = 21/280 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG FG V L Q G A V VKSL+ ++ +F E + L+H +++R
Sbjct: 746 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELEMFGKLNHANVVR 804
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G C P +++E+ GDL+++LR + S+D K +S+ +S
Sbjct: 805 LLGLCREAEPHYMVLEYVDLGDLKQFLRISK---------SKDEK--LKSQPLSTKQKVA 853
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VH+D+ A NCLV ++R++K+ G+++ D + EY
Sbjct: 854 LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSK--DVYNS----EYYHF 907
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG- 823
R+ P+ WM+PE++ G FS+ SDVW+ GVLM E T G+ P+G + VL + +G
Sbjct: 908 RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGK 967
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
R P G CW + +RP+ E+A L D
Sbjct: 968 ARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGD 1007
>AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor
precursor PTK7-3 protein.
Length = 940
Score = 117 bits (282), Expect = 2e-25
Identities = 83/280 (29%), Positives = 132/280 (47%), Gaps = 21/280 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG FG V L Q G A V VKSL+ ++ +F E + L+H +++R
Sbjct: 672 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELEMFGKLNHANVVR 730
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G C P +++E+ GDL+++LR + S+D K +S+ +S
Sbjct: 731 LLGLCREAEPHYMVLEYVDLGDLKQFLRISK---------SKDEK--LKSQPLSTKQKVA 779
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VH+D+ A NCLV ++R++K+ G+++ D + EY
Sbjct: 780 LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSK--DVYNS----EYYHF 833
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG- 823
R+ P+ WM+PE++ G FS+ SDVW+ GVLM E T G+ P+G + VL + +G
Sbjct: 834 RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGK 893
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
R P G CW + +RP+ E+A L D
Sbjct: 894 ARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGD 933
>AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor
precursor PTK7-2 protein.
Length = 1030
Score = 117 bits (282), Expect = 2e-25
Identities = 83/280 (29%), Positives = 132/280 (47%), Gaps = 21/280 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG FG V L Q G A V VKSL+ ++ +F E + L+H +++R
Sbjct: 762 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELEMFGKLNHANVVR 820
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G C P +++E+ GDL+++LR + S+D K +S+ +S
Sbjct: 821 LLGLCREAEPHYMVLEYVDLGDLKQFLRISK---------SKDEK--LKSQPLSTKQKVA 869
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VH+D+ A NCLV ++R++K+ G+++ D + EY
Sbjct: 870 LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSK--DVYNS----EYYHF 923
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG- 823
R+ P+ WM+PE++ G FS+ SDVW+ GVLM E T G+ P+G + VL + +G
Sbjct: 924 RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGK 983
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
R P G CW + +RP+ E+A L D
Sbjct: 984 ARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGD 1023
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 117 bits (282), Expect = 2e-25
Identities = 83/280 (29%), Positives = 132/280 (47%), Gaps = 21/280 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG FG V L Q G A V VKSL+ ++ +F E + L+H +++R
Sbjct: 802 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELEMFGKLNHANVVR 860
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G C P +++E+ GDL+++LR + S+D K +S+ +S
Sbjct: 861 LLGLCREAEPHYMVLEYVDLGDLKQFLRISK---------SKDEK--LKSQPLSTKQKVA 909
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VH+D+ A NCLV ++R++K+ G+++ D + EY
Sbjct: 910 LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSK--DVYNS----EYYHF 963
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG- 823
R+ P+ WM+PE++ G FS+ SDVW+ GVLM E T G+ P+G + VL + +G
Sbjct: 964 RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGK 1023
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
R P G CW + +RP+ E+A L D
Sbjct: 1024 ARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGD 1063
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 117 bits (282), Expect = 2e-25
Identities = 83/280 (29%), Positives = 132/280 (47%), Gaps = 21/280 (7%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG FG V L Q G A V VKSL+ ++ +F E + L+H +++R
Sbjct: 802 LGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQS-KDEQQQLDFRRELEMFGKLNHANVVR 860
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
+G C P +++E+ GDL+++LR + S+D K +S+ +S
Sbjct: 861 LLGLCREAEPHYMVLEYVDLGDLKQFLRISK---------SKDEK--LKSQPLSTKQKVA 909
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
VH+D+ A NCLV ++R++K+ G+++ D + EY
Sbjct: 910 LCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSK--DVYNS----EYYHF 963
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSG- 823
R+ P+ WM+PE++ G FS+ SDVW+ GVLM E T G+ P+G + VL + +G
Sbjct: 964 RQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGK 1023
Query: 824 GRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYLRD 863
R P G CW + +RP+ E+A L D
Sbjct: 1024 ARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGD 1063
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 117 bits (282), Expect = 2e-25
Identities = 79/283 (27%), Positives = 121/283 (42%), Gaps = 15/283 (5%)
Query: 587 LGTGRFGRVHLGVLQVPGKAP-RP---VAVKSLRKGAAPAEETEFLNEAVIMAALDHEHI 642
+G G FGRV + PG P P VAVK L++ A+ + +F EA +MA D+ +I
Sbjct: 581 IGEGAFGRVFQA--RAPGLLPYEPFTMVAVKMLKEEASADMQADFQREAALMAEFDNPNI 638
Query: 643 IRFVGACVAKGPPLVLMEHAFFGDLRRYLRERR-HFAEQSDHLSQDSKDFEESEH---VS 698
++ +G C P +L E+ +GDL +LR H H + S +S
Sbjct: 639 VKLLGVCAVGKPMCLLFEYMAYGDLNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLS 698
Query: 699 XXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGA 758
R VHRD+ NCLV +K+ DFG++R + A
Sbjct: 699 CAEQLCIARQVAAGMAYLSERKFVHRDLATRNCLVGENMVVKIADFGLSRNIYS-----A 753
Query: 759 AEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQ 818
Y P+ WM PES+ +++ SDVW+ GV++ E + G +PY + V+
Sbjct: 754 DYYKANENDAIPIRWMPPESIFYNRYTTESDVWAYGVVLWEIFSYGLQPYYGMAHEEVIY 813
Query: 819 HVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
+V G P CW + +RP+ + R L
Sbjct: 814 YVRDGNILSCPENCPVELYNLMRLCWSKLPADRPSFTSIHRIL 856
>X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRNA
encoding p150 protein. ).
Length = 1130
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 248 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 302
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 303 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 344
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 345 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 398
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 399 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 458
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 459 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1130
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 248 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 302
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 303 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 344
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 345 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 398
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 399 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 458
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 459 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene
tyrosine-protein kinase protein.
Length = 1149
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 267 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 321
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 322 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 363
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 364 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 417
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 418 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 477
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 478 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 267 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 321
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 322 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 363
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 364 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 417
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 418 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 477
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 478 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 267 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 321
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 322 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 363
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 364 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 417
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 418 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 477
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 478 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 267 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 321
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 322 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 363
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 364 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 417
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 418 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 477
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 478 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1149
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 267 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 321
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 322 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 363
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 364 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 417
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 418 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 477
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 478 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 508
>AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 protein.
Length = 1130
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 248 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 302
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 303 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 344
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 345 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 398
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 399 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 458
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 459 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine
leukemia viral oncogene homolog 1 isoform b variant
protein.
Length = 1167
Score = 117 bits (281), Expect = 2e-25
Identities = 80/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 285 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 339
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 340 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 381
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 382 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 435
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 436 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRM 495
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
E P G CW+ +RP+ E+
Sbjct: 496 ERPEGCPEKVYELMRACWQWNPSDRPSFAEI 526
>S76475-1|AAB33111.1| 839|Homo sapiens trkC protein.
Length = 839
Score = 116 bits (279), Expect = 4e-25
Identities = 82/286 (28%), Positives = 125/286 (43%), Gaps = 16/286 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P K VAVK+L+ A + +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DFQREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P +++ E+ GDL ++LR A + D + + +
Sbjct: 603 FYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAM----ILVDGQPRQAKGELGLSQMLH 658
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT---------GA 755
+ VHRD+ NCLV + +K+GDFGM+R +T G
Sbjct: 659 IASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGN 718
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S
Sbjct: 719 DFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTE 778
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
V++ ++ G E P CW+R +R E+ + L
Sbjct: 779 VIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 824
>AJ224521-1|CAA12029.1| 839|Homo sapiens TRKC protein.
Length = 839
Score = 116 bits (279), Expect = 4e-25
Identities = 82/286 (28%), Positives = 125/286 (43%), Gaps = 16/286 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P K VAVK+L+ A + +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLSPTKDKMLVAVKALKDPTLAARK-DFQREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G C P +++ E+ GDL ++LR A + D + + +
Sbjct: 603 FYGVCGDGDPLIMVFEYMKHGDLNKFLRAHGPDAM----ILVDGQPRQAKGELGLSQMLH 658
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDAT---------GA 755
+ VHRD+ NCLV + +K+GDFGM+R +T G
Sbjct: 659 IASQIASGMVYLASQHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYRLFNPSGN 718
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D + P+ WM PES+ F++ SDVWS GV++ E T G +P+ S
Sbjct: 719 DFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNTE 778
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVARYL 861
V++ ++ G E P CW+R +R E+ + L
Sbjct: 779 VIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKIL 824
>U19348-1|AAA92686.1| 523|Homo sapiens tpr-met fusion protein
protein.
Length = 523
Score = 116 bits (278), Expect = 5e-25
Identities = 82/296 (27%), Positives = 138/296 (46%), Gaps = 25/296 (8%)
Query: 565 PPVTQELTRFLVDPAHLVTY--DILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPA 622
P + Q + ++ P+ L+ + +++G G FG V+ G L AVKSL +
Sbjct: 193 PELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIG 252
Query: 623 EETEFLNEAVIMAALDHEHIIRFVGACV-AKGPPLVLMEHAFFGDLRRYLRERRHFAEQS 681
E ++FL E +IM H +++ +G C+ ++G PLV++ + GDLR ++R H
Sbjct: 253 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVK 312
Query: 682 DHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKL 741
D + + + ++++ + VHRD+ A NC++D + +K+
Sbjct: 313 DLIGFGLQVAKGMKYLAS-------------------KKFVHRDLAARNCMLDEKFTVKV 353
Query: 742 GDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETV 801
DFG+AR D + + + + PV WMA ESL F++ SDVWS GVL+ E +
Sbjct: 354 ADFGLAR--DMYDKEYYSVHN-KTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELM 410
Query: 802 TLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
T G PY + + ++ G R P CW A RP+ E+
Sbjct: 411 TRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 466
>U08818-1|AAB60323.1| 455|Homo sapiens activated met oncogene
protein.
Length = 455
Score = 116 bits (278), Expect = 5e-25
Identities = 82/296 (27%), Positives = 138/296 (46%), Gaps = 25/296 (8%)
Query: 565 PPVTQELTRFLVDPAHLVTY--DILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPA 622
P + Q + ++ P+ L+ + +++G G FG V+ G L AVKSL +
Sbjct: 125 PELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIG 184
Query: 623 EETEFLNEAVIMAALDHEHIIRFVGACV-AKGPPLVLMEHAFFGDLRRYLRERRHFAEQS 681
E ++FL E +IM H +++ +G C+ ++G PLV++ + GDLR ++R H
Sbjct: 185 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVK 244
Query: 682 DHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKL 741
D + + + ++++ + VHRD+ A NC++D + +K+
Sbjct: 245 DLIGFGLQVAKGMKYLAS-------------------KKFVHRDLAARNCMLDEKFTVKV 285
Query: 742 GDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETV 801
DFG+AR D + + + + PV WMA ESL F++ SDVWS GVL+ E +
Sbjct: 286 ADFGLAR--DMYDKEYYSVHN-KTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELM 342
Query: 802 TLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
T G PY + + ++ G R P CW A RP+ E+
Sbjct: 343 TRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 398
>M14752-1|AAA51561.1| 1130|Homo sapiens ABL1 protein.
Length = 1130
Score = 116 bits (278), Expect = 5e-25
Identities = 79/271 (29%), Positives = 120/271 (44%), Gaps = 29/271 (10%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +
Sbjct: 248 LGGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLL 302
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G C + P ++ E +G+L YLRE + V+
Sbjct: 303 GVCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMA 344
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 345 TQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAG 398
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R
Sbjct: 399 AKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDRSQVYELLEKDYRM 458
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
+ P G CW+ +RP+ E+
Sbjct: 459 KRPEGCPEKVYELMRACWQWNPSDRPSFAEI 489
>BC130420-1|AAI30421.1| 1390|Homo sapiens met proto-oncogene
(hepatocyte growth factor receptor) protein.
Length = 1390
Score = 116 bits (278), Expect = 5e-25
Identities = 82/296 (27%), Positives = 138/296 (46%), Gaps = 25/296 (8%)
Query: 565 PPVTQELTRFLVDPAHLVTY--DILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPA 622
P + Q + ++ P+ L+ + +++G G FG V+ G L AVKSL +
Sbjct: 1060 PELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIG 1119
Query: 623 EETEFLNEAVIMAALDHEHIIRFVGACV-AKGPPLVLMEHAFFGDLRRYLRERRHFAEQS 681
E ++FL E +IM H +++ +G C+ ++G PLV++ + GDLR ++R H
Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVK 1179
Query: 682 DHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKL 741
D + + + ++++ + VHRD+ A NC++D + +K+
Sbjct: 1180 DLIGFGLQVAKGMKYLAS-------------------KKFVHRDLAARNCMLDEKFTVKV 1220
Query: 742 GDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETV 801
DFG+AR D + + + + PV WMA ESL F++ SDVWS GVL+ E +
Sbjct: 1221 ADFGLAR--DMYDKEYYSVHN-KTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELM 1277
Query: 802 TLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
T G PY + + ++ G R P CW A RP+ E+
Sbjct: 1278 TRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1333
>AB209898-1|BAD93135.1| 712|Homo sapiens met proto-oncogene
precursor variant protein.
Length = 712
Score = 116 bits (278), Expect = 5e-25
Identities = 82/296 (27%), Positives = 138/296 (46%), Gaps = 25/296 (8%)
Query: 565 PPVTQELTRFLVDPAHLVTY--DILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPA 622
P + Q + ++ P+ L+ + +++G G FG V+ G L AVKSL +
Sbjct: 382 PELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIG 441
Query: 623 EETEFLNEAVIMAALDHEHIIRFVGACV-AKGPPLVLMEHAFFGDLRRYLRERRHFAEQS 681
E ++FL E +IM H +++ +G C+ ++G PLV++ + GDLR ++R H
Sbjct: 442 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVK 501
Query: 682 DHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKL 741
D + + + ++++ + VHRD+ A NC++D + +K+
Sbjct: 502 DLIGFGLQVAKGMKYLAS-------------------KKFVHRDLAARNCMLDEKFTVKV 542
Query: 742 GDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETV 801
DFG+AR D + + + + PV WMA ESL F++ SDVWS GVL+ E +
Sbjct: 543 ADFGLAR--DMYDKEYYSVHN-KTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELM 599
Query: 802 TLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
T G PY + + ++ G R P CW A RP+ E+
Sbjct: 600 TRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 655
>Y00665-1|CAA68679.1| 622|Homo sapiens tyrosine kinase protein.
Length = 622
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 284 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 343
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 344 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 399
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 400 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 454
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 455 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 514
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 515 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 545
>X66945-1|CAA47375.1| 822|Homo sapiens fibroblast growth factor
receptor protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 599
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 654
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 714
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 715 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 745
>X57122-1|CAA40404.1| 731|Homo sapiens Fibroblast Growth Factor
Receptor, 2 Ig-Domain Form protein.
Length = 731
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 393 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 452
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 453 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 508
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 509 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 563
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 564 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 623
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 624 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 654
>X57121-1|CAA40403.1| 822|Homo sapiens Fibroblast Growth Factor
Receptor, 3-Ig Domain+2orm protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 599
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 654
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 714
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 715 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 745
>X57120-1|CAA40402.1| 820|Homo sapiens Fibroblast Growth Factor
Receptor, 3 Ig-Domain Form protein.
Length = 820
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 482 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 541
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 542 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 597
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 598 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 652
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 653 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 712
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 713 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 743
>X57119-1|CAA40401.1| 733|Homo sapiens Fibroblast Growth Factor
Receptor, 2-Ig Domain+25-1 protein.
Length = 733
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 395 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 454
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 455 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 510
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 511 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 565
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 566 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 625
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 626 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 656
>X52833-1|CAA37015.1| 822|Homo sapiens protein ( Human flg mRNA for
fibroblast growth factor receptor-FLG. ).
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 599
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 654
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 714
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 715 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 745
>X51803-1|CAA36101.1| 822|Homo sapiens protein ( Human mRNA for
fibroblast growth factor (FGF) receptor. ).
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 599
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 654
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 714
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 715 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 745
>U12140-1|AAC51371.1| 822|Homo sapiens tyrosine kinase receptor
p145TRK-B protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 603 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 655
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 656 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 710
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 711 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 770
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 771 VLQRPRTCPQEVYELMLGCWQR 792
>S76473-1|AAB33109.1| 822|Homo sapiens trkB protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 603 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 655
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 656 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 710
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 711 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 770
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 771 VLQRPRTCPQEVYELMLGCWQR 792
>M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth
factor receptor protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 599
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 654
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 714
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 715 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 745
>M60485-1|AAA35840.1| 820|Homo sapiens fibroblast growth factor
receptor protein.
Length = 820
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 482 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 541
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 542 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 597
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 598 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 652
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 653 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 712
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 713 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 743
>M37722-1|AAA75007.1| 731|Homo sapiens basic fibroblast growth
factor receptor protein protein.
Length = 731
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 393 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 452
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 453 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 508
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 509 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 563
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 564 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 623
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 624 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 654
>M34641-1|AAA35835.1| 820|Homo sapiens protein ( Human fibroblast
growth factor (FGF) receptor-1 mRNA, complete cds. ).
Length = 820
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 482 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 541
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 542 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 597
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 598 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 652
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 653 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 712
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 713 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 743
>M34186-1|AAA35837.1| 731|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 731
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 393 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 452
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 453 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 508
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 509 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 563
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 564 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 623
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 624 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 654
>M34185-1|AAA35836.1| 733|Homo sapiens protein ( Human fibroblast
growth factor receptor (FGFr) transmembrane form mRNA,
complete cds. ).
Length = 733
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 395 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 454
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 455 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 510
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 511 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 565
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 566 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 625
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 626 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 656
>BC091494-1|AAH91494.1| 731|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 731
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 393 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 452
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 453 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 508
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 509 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 563
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 564 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 623
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 624 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 654
>BC018128-1|AAH18128.1| 820|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 820
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 482 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 541
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 542 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 597
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 598 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 652
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 653 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 712
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 713 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 743
>BC015035-1|AAH15035.1| 820|Homo sapiens FGFR1 protein protein.
Length = 820
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 482 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 541
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 542 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 597
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 598 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 652
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 653 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 712
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 713 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 743
>AY585209-1|AAS79322.1| 822|Homo sapiens fibroblast growth factor
receptor 1 (fms-related tyrosine kinase 2, Pfeiffer sy
protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 484 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 543
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 544 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 599
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 654
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 655 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 714
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 715 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 745
>AL596132-4|CAH72315.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 603 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 655
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 656 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 710
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 711 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 770
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 771 VLQRPRTCPQEVYELMLGCWQR 792
>AL596132-3|CAH72316.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 560 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 618
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 619 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 671
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 672 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 726
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 727 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 786
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 787 VLQRPRTCPQEVYELMLGCWQR 808
>AL445532-2|CAH71817.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 603 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 655
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 656 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 710
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 711 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 770
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 771 VLQRPRTCPQEVYELMLGCWQR 792
>AL445532-1|CAH71816.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 560 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 618
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 619 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 671
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 672 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 726
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 727 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 786
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 787 VLQRPRTCPQEVYELMLGCWQR 808
>AL390777-4|CAH72196.1| 822|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 603 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 655
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 656 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 710
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 711 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 770
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 771 VLQRPRTCPQEVYELMLGCWQR 792
>AL390777-3|CAH72195.1| 838|Homo sapiens neurotrophic tyrosine
kinase, receptor, type 2 protein.
Length = 838
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 560 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 618
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 619 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 671
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 672 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 726
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 727 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 786
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 787 VLQRPRTCPQEVYELMLGCWQR 808
>AK131215-1|BAD18404.1| 543|Homo sapiens protein ( Homo sapiens
cDNA FLJ16103 fis, clone TESTI2016663, moderately
similar to EPHRIN TYPE-A RECEPTOR 7 PRECURSOR (EC
2.7.1.112). ).
Length = 543
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 116/271 (42%), Gaps = 25/271 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG GRFG + G LQ+PG+ VAV LR A+ ++ FL EA+ + DH HI+R
Sbjct: 146 LGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLE 205
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G +++ E+ G L +LR RH E + V+
Sbjct: 206 GVVTRGSTLMIVTEYMSHGALDGFLR--RH----------------EGQLVAGQLMGLLP 247
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
G VHR + A + LV S K+ FG + D +
Sbjct: 248 GLASAMKYLS-EMGYVHRGLAAHHVLVSSDLVCKISGFGRGPR------DRSEAVYTTMS 300
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
G P LW APE+L G FSSASDVWS G++M E + G+RPY S V++ V G R
Sbjct: 301 GRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRL 360
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
P CW++ ERP ++
Sbjct: 361 PPPRNCPNLLHRLMLDCWQKDPGERPRFSQI 391
>AJ872185-1|CAI43321.1| 1008|Homo sapiens Ephrin type-A receptor 10
protein.
Length = 1008
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 116/271 (42%), Gaps = 25/271 (9%)
Query: 587 LGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFV 646
LG GRFG + G LQ+PG+ VAV LR A+ ++ FL EA+ + DH HI+R
Sbjct: 651 LGGGRFGELCCGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLE 710
Query: 647 GACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXX 706
G +++ E+ G L +LR RH E + V+
Sbjct: 711 GVVTRGSTLMIVTEYMSHGALDGFLR--RH----------------EGQLVAGQLMGLLP 752
Query: 707 XXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRR 766
G VHR + A + LV S K+ FG + D +
Sbjct: 753 GLASAMKYLS-EMGYVHRGLAARHVLVSSDLVCKISGFGRGPR------DRSEAVYTTMS 805
Query: 767 GLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRP 826
G P LW APE+L G FSSASDVWS G++M E + G+RPY S V++ V G R
Sbjct: 806 GRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVMAFGERPYWDMSGQDVIKAVEDGFRL 865
Query: 827 ELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
P CW++ ERP ++
Sbjct: 866 PPPRNCPNLLHRLMLDCWQKDPGERPRFSQI 896
>AF410899-1|AAL67965.1| 838|Homo sapiens neurotrophin receptor
tyrosine kinase type 2 protein.
Length = 838
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 560 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 618
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 619 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 671
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 672 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 726
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 727 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 786
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 787 VLQRPRTCPQEVYELMLGCWQR 808
>AF400441-1|AAK92490.1| 822|Homo sapiens neurotrophic tyrosine
kinase receptor type 2 protein.
Length = 822
Score = 115 bits (277), Expect = 6e-25
Identities = 78/262 (29%), Positives = 121/262 (46%), Gaps = 15/262 (5%)
Query: 587 LGTGRFGRVHLGVLQ--VPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIR 644
LG G FG+V L P + VAVK+L K A+ +F EA ++ L HEHI++
Sbjct: 544 LGEGAFGKVFLAECYNLCPEQDKILVAVKTL-KDASDNARKDFHREAELLTNLQHEHIVK 602
Query: 645 FVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXX 704
F G CV P +++ E+ GDL ++LR + +++ + E ++
Sbjct: 603 FYGVCVEGDPLIMVFEYMKHGDLNKFLRAH---GPDAVLMAEGNPPTE----LTQSQMLH 655
Query: 705 XXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACR 764
+ VHRD+ NCLV +K+GDFGM+R +T Y
Sbjct: 656 IAQQIAAGMVYLASQHFVHRDLATRNCLVGENLLVKIGDFGMSRDVYSTDY-----YRVG 710
Query: 765 RRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGG 824
+ P+ WM PES+ F++ SDVWSLGV++ E T G +P+ S V++ ++ G
Sbjct: 711 GHTMLPIRWMPPESIMYRKFTTESDVWSLGVVLWEIFTYGKQPWYQLSNNEVIECITQGR 770
Query: 825 RPELPFGXXXXXXXXXXXCWRR 846
+ P CW+R
Sbjct: 771 VLQRPRTCPQEVYELMLGCWQR 792
>AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene
tyrosine-protein kinase ABL1 variant protein.
Length = 949
Score = 115 bits (277), Expect = 6e-25
Identities = 79/270 (29%), Positives = 119/270 (44%), Gaps = 29/270 (10%)
Query: 588 GTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVG 647
G G++G V+ GV + K VAVK+L++ EE FL EA +M + H ++++ +G
Sbjct: 68 GGGQYGEVYEGVWK---KYSLTVAVKTLKEDTMEVEE--FLKEAAVMKEIKHPNLVQLLG 122
Query: 648 ACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXX 707
C + P ++ E +G+L YLRE + V+
Sbjct: 123 VCTREPPFYIITEFMTYGNLLDYLRECNR------------------QEVNAVVLLYMAT 164
Query: 708 XXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEYACRRRG 767
++ +HRD+ A NCLV +K+ DFG++R TG Y
Sbjct: 165 QISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLM--TGDT----YTAHAGA 218
Query: 768 LFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPE 827
FP+ W APESL+ FS SDVW+ GVL+ E T G PY +V + + R E
Sbjct: 219 KFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRME 278
Query: 828 LPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
P G CW+ +RP+ E+
Sbjct: 279 RPEGCPEKVYELMRACWQWNPSDRPSFAEI 308
>AB208919-1|BAD92156.1| 814|Homo sapiens fibroblast growth factor
receptor 1 isoform 1 precursor variant protein.
Length = 814
Score = 115 bits (277), Expect = 6e-25
Identities = 84/271 (30%), Positives = 122/271 (45%), Gaps = 14/271 (5%)
Query: 587 LGTGRFGRVHLG-VLQVPGKAPR---PVAVKSLRKGAAPAEETEFLNEAVIMAALD-HEH 641
LG G FG+V L + + P VAVK L+ A + ++ ++E +M + H++
Sbjct: 476 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 535
Query: 642 IIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESEHVSXXX 701
II +GAC GP V++E+A G+LR YL+ RR ++ S + EE +S
Sbjct: 536 IINLLGACTQDGPLYVIVEYASKGNLREYLQARR--PPGLEYCYNPSHNPEEQ--LSSKD 591
Query: 702 XXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGADGAAEY 761
+ +HRD+ A N LV +K+ DFG+AR D D Y
Sbjct: 592 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLAR--DIHHID---YY 646
Query: 762 ACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLRVLQHVS 821
G PV WMAPE+L ++ SDVWS GVL+ E TLG PY + + +
Sbjct: 647 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 706
Query: 822 SGGRPELPFGXXXXXXXXXXXCWRRAACERP 852
G R + P CW +RP
Sbjct: 707 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRP 737
>J02958-1|AAA59591.1| 1408|Homo sapiens MET protein.
Length = 1408
Score = 115 bits (276), Expect = 9e-25
Identities = 81/296 (27%), Positives = 138/296 (46%), Gaps = 25/296 (8%)
Query: 565 PPVTQELTRFLVDPAHLVTY--DILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPA 622
P + Q + ++ P+ L+ + +++G G FG V+ G L AVKSL +
Sbjct: 1078 PELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIG 1137
Query: 623 EETEFLNEAVIMAALDHEHIIRFVGACV-AKGPPLVLMEHAFFGDLRRYLRERRHFAEQS 681
E ++FL E +IM H +++ +G C+ ++G PLV++ + GDLR ++R H
Sbjct: 1138 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVK 1197
Query: 682 DHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKL 741
D + + + ++++ + VHRD+ A NC++D + +K+
Sbjct: 1198 DLIGFGLQVAKAMKYLAS-------------------KKFVHRDLAARNCMLDEKFTVKV 1238
Query: 742 GDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETV 801
DFG+AR D + + + + PV WMA ESL F++ SDVWS GV++ E +
Sbjct: 1239 ADFGLAR--DMYDKEYYSVHN-KTGAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELM 1295
Query: 802 TLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
T G PY + + ++ G R P CW A RP+ E+
Sbjct: 1296 TRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1351
>X54559-1|CAB56793.1| 1390|Homo sapiens proto-oncogene protein.
Length = 1390
Score = 114 bits (275), Expect = 1e-24
Identities = 81/296 (27%), Positives = 138/296 (46%), Gaps = 25/296 (8%)
Query: 565 PPVTQELTRFLVDPAHLVTY--DILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPA 622
P + Q + ++ P+ L+ + +++G G FG V+ G L AVKSL +
Sbjct: 1060 PELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIG 1119
Query: 623 EETEFLNEAVIMAALDHEHIIRFVGACV-AKGPPLVLMEHAFFGDLRRYLRERRHFAEQS 681
E ++FL E +IM H +++ +G C+ ++G PLV++ + GDLR ++R H
Sbjct: 1120 EVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVK 1179
Query: 682 DHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKL 741
D + + + ++++ + VHRD+ A NC++D + +K+
Sbjct: 1180 DLIGFGLQVAKGMKYLAS-------------------KKFVHRDLAARNCMLDEKFTVKV 1220
Query: 742 GDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETV 801
DFG+AR D + + + + PV WMA ESL F++ SDVWS GV++ E +
Sbjct: 1221 ADFGLAR--DMYDKEYYSVHN-KTGAKLPVKWMALESLQTQKFTTKSDVWSFGVVLWELM 1277
Query: 802 TLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEV 857
T G PY + + ++ G R P CW A RP+ E+
Sbjct: 1278 TRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSEL 1333
>BC101713-1|AAI01714.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 114 bits (275), Expect = 1e-24
Identities = 87/284 (30%), Positives = 126/284 (44%), Gaps = 31/284 (10%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
++P+ L LG+G FG V LG +A VA+K++R+GA E+ F+ EA +M
Sbjct: 365 INPSELTFMRELGSGLFGVVRLG----KWRAQYKVAIKAIREGAMCEED--FIEEAKVMM 418
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
L H +++ G C + P ++ E G L +LR+R+ + LS E E
Sbjct: 419 KLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGME 478
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
++ R +HRD+ A NCLV +K+ DFGMAR
Sbjct: 479 YLE-------------------RNSFIHRDLAARNCLVSEAGVVKVSDFGMARYV----L 515
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D +Y FPV W PE + FSS SDVWS GVLM E T G P+ ++
Sbjct: 516 DD--QYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYE 573
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVAR 859
V+ V+ G R P CW+ RP+ ++ R
Sbjct: 574 VVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLR 617
>BC101711-1|AAI01712.1| 631|Homo sapiens tec protein tyrosine
kinase protein.
Length = 631
Score = 114 bits (275), Expect = 1e-24
Identities = 87/284 (30%), Positives = 126/284 (44%), Gaps = 31/284 (10%)
Query: 576 VDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPRPVAVKSLRKGAAPAEETEFLNEAVIMA 635
++P+ L LG+G FG V LG +A VA+K++R+GA E+ F+ EA +M
Sbjct: 365 INPSELTFMRELGSGLFGVVRLG----KWRAQYKVAIKAIREGAMCEED--FIEEAKVMM 418
Query: 636 ALDHEHIIRFVGACVAKGPPLVLMEHAFFGDLRRYLRERRHFAEQSDHLSQDSKDFEESE 695
L H +++ G C + P ++ E G L +LR+R+ + LS E E
Sbjct: 419 KLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGME 478
Query: 696 HVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNCLVDSRRRLKLGDFGMARKTDATGA 755
++ R +HRD+ A NCLV +K+ DFGMAR
Sbjct: 479 YLE-------------------RNSFIHRDLAARNCLVSEAGVVKVSDFGMARYV----L 515
Query: 756 DGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVWSLGVLMLETVTLGDRPYGSWSPLR 815
D +Y FPV W PE + FSS SDVWS GVLM E T G P+ ++
Sbjct: 516 DD--QYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYE 573
Query: 816 VLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACERPAAGEVAR 859
V+ V+ G R P CW+ RP+ ++ R
Sbjct: 574 VVTMVTRGHRLYQPKLASNYVYEVMLRCWQEKPEGRPSFEDLLR 617
>L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase
protein.
Length = 1308
Score = 114 bits (274), Expect = 1e-24
Identities = 92/321 (28%), Positives = 137/321 (42%), Gaps = 36/321 (11%)
Query: 555 LASVIRPAKLPPVTQELTRFLVDPAHLVTYDILGTGRFGRVHLGVLQVPGKAPR-PVAVK 613
L + P+ P +L ++ L +LG+G FG V+ G+ G+ + PVA+K
Sbjct: 694 LVEPLTPSGTAPNQAQLR--ILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIK 751
Query: 614 SLRKGAAPAEETEFLNEAVIMAALDHEHIIRFVGACVAKGPPLV--LMEHAFFGDLRRYL 671
L + P EF++EA+IMA++DH H++R +G C++ LV LM H G L Y+
Sbjct: 752 ILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPH---GCLLEYV 808
Query: 672 RERRHFAEQSDHLSQDSKDFEESEHVSXXXXXXXXXXXXXXXXXXXRRGVVHRDVRASNC 731
E + +++ R +VHRD+ A N
Sbjct: 809 HEHK-------------------DNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNV 849
Query: 732 LVDSRRRLKLGDFGMARKTDATGADGAAEYACRRRGLFPVLWMAPESLSRGAFSSASDVW 791
LV S +K+ DFG+AR + + A+ G P+ WMA E + F+ SDVW
Sbjct: 850 LVKSPNHVKITDFGLARLLEGDEKEYNAD-----GGKMPIKWMALECIHYRKFTHQSDVW 904
Query: 792 SLGVLMLETVTLGDRPYGSWSPLRVLQHVSSGGRPELPFGXXXXXXXXXXXCWRRAACER 851
S GV + E +T G +PY + + G R P CW A R
Sbjct: 905 SYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSR 964
Query: 852 P----AAGEVARYLRDHPRAL 868
P A E +R RD R L
Sbjct: 965 PKFKELAAEFSRMARDPQRYL 985
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.137 0.415
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 124,264,245
Number of Sequences: 224733
Number of extensions: 5018746
Number of successful extensions: 14284
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1593
Number of HSP's successfully gapped in prelim test: 740
Number of HSP's that attempted gapping in prelim test: 9235
Number of HSP's gapped (non-prelim): 3619
length of query: 892
length of database: 73,234,838
effective HSP length: 97
effective length of query: 795
effective length of database: 51,435,737
effective search space: 40891410915
effective search space used: 40891410915
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 70 (32.3 bits)
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