Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA003385-TA|BGIBMGA003385-PA|IPR000959|POLO box duplicated
region, IPR008271|Serine/threonine protein kinase, active site,
IPR000719|Protein kinase, IPR011009|Protein kinase-like,
IPR002290|Serine/threonine protein kinase
(459 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 532 e-151
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 532 e-151
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 532 e-151
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 532 e-151
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 532 e-151
AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase varian... 532 e-151
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 528 e-149
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 526 e-149
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 230 7e-60
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 230 7e-60
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 230 7e-60
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 230 7e-60
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 230 7e-60
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 230 7e-60
U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase pr... 227 5e-59
BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2 (Dro... 227 5e-59
AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens ... 227 5e-59
AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase ... 227 5e-59
AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase ... 227 5e-59
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 182 2e-45
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 181 5e-45
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 181 5e-45
AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens ... 170 8e-42
AB084459-1|BAD93352.1| 247|Homo sapiens polo-like kinase 1 delt... 146 2e-34
BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein. 138 5e-32
BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein. 138 5e-32
BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein. 138 5e-32
BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein. 138 5e-32
AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein. 138 5e-32
AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine ... 138 5e-32
AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase... 138 5e-32
AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1... 138 5e-32
D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinas... 135 4e-31
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 130 8e-30
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 130 8e-30
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 130 8e-30
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 130 8e-30
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 130 8e-30
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 129 2e-29
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 129 2e-29
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 129 2e-29
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 129 2e-29
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 129 2e-29
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 129 2e-29
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 129 2e-29
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 129 2e-29
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 129 2e-29
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 129 2e-29
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 129 2e-29
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 129 2e-29
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 129 2e-29
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 129 2e-29
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 129 2e-29
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 129 2e-29
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 128 4e-29
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 128 4e-29
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 127 9e-29
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 127 9e-29
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 127 9e-29
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 127 9e-29
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 126 1e-28
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 126 1e-28
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 126 1e-28
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 125 3e-28
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 125 3e-28
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 125 3e-28
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 125 3e-28
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 125 3e-28
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 125 3e-28
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 125 3e-28
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 125 3e-28
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 125 3e-28
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 125 3e-28
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 125 3e-28
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 125 3e-28
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 125 3e-28
AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta ... 125 3e-28
BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein. 125 4e-28
AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein. 125 4e-28
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 124 5e-28
AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protei... 124 9e-28
X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha... 123 1e-27
BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha... 123 1e-27
BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha... 123 1e-27
AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6... 123 1e-27
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 122 2e-27
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 122 2e-27
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 122 2e-27
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 122 2e-27
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 122 2e-27
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 122 2e-27
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 122 2e-27
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 122 2e-27
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 122 2e-27
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 122 3e-27
X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon... 122 3e-27
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 122 3e-27
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 122 3e-27
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 122 3e-27
L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kina... 122 3e-27
BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsil... 122 3e-27
BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsil... 122 3e-27
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 122 3e-27
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 122 3e-27
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 122 3e-27
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 122 3e-27
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 122 3e-27
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 122 3e-27
AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein. 122 3e-27
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 122 3e-27
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 122 3e-27
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 122 3e-27
M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha ... 122 4e-27
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 122 4e-27
BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma vi... 122 4e-27
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 122 4e-27
BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma vi... 122 4e-27
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 122 4e-27
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 122 4e-27
AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein. 122 4e-27
X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B p... 121 5e-27
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 121 5e-27
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 121 5e-27
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 121 5e-27
Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma pr... 121 6e-27
M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase a... 121 6e-27
M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase a... 121 6e-27
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 121 6e-27
BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein. 121 6e-27
BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma... 121 6e-27
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 121 6e-27
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 121 6e-27
BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6 ki... 121 6e-27
BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6 ki... 121 6e-27
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 121 6e-27
AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6 ki... 121 6e-27
AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma ... 121 6e-27
AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinas... 121 6e-27
AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase... 121 6e-27
AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein. 121 6e-27
AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase... 121 6e-27
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 120 8e-27
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 120 8e-27
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 120 8e-27
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 120 8e-27
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 120 8e-27
BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein. 120 8e-27
AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma ... 120 8e-27
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma vi... 120 8e-27
AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma vi... 120 8e-27
AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma vi... 120 8e-27
AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma vi... 120 8e-27
AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma vi... 120 8e-27
AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma vi... 120 8e-27
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 120 8e-27
AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein. 120 8e-27
AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase pro... 120 8e-27
AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma ... 120 8e-27
AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein. 120 8e-27
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 120 1e-26
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 120 1e-26
L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota pro... 119 2e-26
L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota pro... 119 2e-26
Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kina... 118 3e-26
X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein. 118 3e-26
X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for ... 118 3e-26
X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for ... 118 3e-26
M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II ... 118 3e-26
L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kina... 118 3e-26
BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta ... 118 3e-26
BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota ... 118 3e-26
BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6 ki... 118 3e-26
AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6 ki... 118 3e-26
AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (... 118 3e-26
AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (... 118 3e-26
AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6 ki... 118 3e-26
BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma vi... 118 4e-26
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 118 4e-26
X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for ... 118 6e-26
DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase, cAMP-de... 118 6e-26
BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase, cAMP-de... 118 6e-26
BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase, cAMP-de... 118 6e-26
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 117 8e-26
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 117 8e-26
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 117 8e-26
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 117 8e-26
M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein ki... 117 1e-25
DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase, cAMP-de... 117 1e-25
AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase, cAMP-d... 117 1e-25
AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase, cAMP-de... 117 1e-25
AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase, cAMP-de... 117 1e-25
AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase, cAMP-de... 117 1e-25
AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein ... 117 1e-25
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 116 2e-25
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 116 2e-25
Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein. 116 2e-25
CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein. 116 2e-25
BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase... 116 2e-25
BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein. 116 2e-25
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 116 2e-25
BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase, cAMP-de... 116 2e-25
BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein. 116 2e-25
BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide depe... 116 2e-25
BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein. 116 2e-25
BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein. 116 2e-25
AL022069-1|CAI19650.1| 166|Homo sapiens ribosomal protein S6 ki... 116 2e-25
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 116 2e-25
AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide depe... 116 2e-25
AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2... 116 2e-25
AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein. 116 2e-25
AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide depe... 116 2e-25
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 116 2e-25
AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like mi... 116 2e-25
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 115 4e-25
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 115 4e-25
BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein MG... 115 4e-25
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 115 4e-25
AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide depe... 114 5e-25
AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein. 113 9e-25
BC034044-1|AAH34044.1| 527|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL713896-5|CAI13788.1| 516|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL713896-2|CAI13791.1| 527|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL596247-5|CAI13967.1| 516|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AL596247-2|CAI13968.1| 527|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein. 113 1e-24
AF415197-1|AAM33514.1| 566|Homo sapiens calcium/calmodulin-depe... 113 1e-24
AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein. 113 1e-24
AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase... 113 2e-24
M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein. 112 2e-24
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 112 2e-24
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 112 2e-24
BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta p... 112 2e-24
AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid re... 112 2e-24
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 112 2e-24
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 112 2e-24
BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein. 112 3e-24
AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein. 112 3e-24
AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kin... 112 3e-24
AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase... 112 3e-24
AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kin... 112 3e-24
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 111 4e-24
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 111 4e-24
BC016285-1|AAH16285.1| 257|Homo sapiens protein kinase, cAMP-de... 111 5e-24
AL450063-11|CAI16854.1| 264|Homo sapiens protein kinase, cAMP-d... 111 5e-24
AL450063-7|CAI16850.1| 245|Homo sapiens protein kinase, cAMP-de... 111 5e-24
AL450063-1|CAI16844.1| 257|Homo sapiens protein kinase, cAMP-de... 111 5e-24
AL359504-1|CAI14540.1| 257|Homo sapiens protein kinase, cAMP-de... 111 5e-24
AF059681-1|AAC77369.1| 275|Homo sapiens serine/threonine kinase... 111 5e-24
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 111 7e-24
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 111 7e-24
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 111 7e-24
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 111 7e-24
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 111 7e-24
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 111 7e-24
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 111 7e-24
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 111 7e-24
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 111 7e-24
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 111 7e-24
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 111 7e-24
AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 111 7e-24
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 111 7e-24
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 111 7e-24
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 111 7e-24
AB209055-1|BAD92292.1| 272|Homo sapiens phosphorylase kinase, g... 111 7e-24
U66064-1|AAB80848.1| 315|Homo sapiens calcium/calmodulin-depend... 110 9e-24
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 110 9e-24
L07043-1|AAB61379.1| 306|Homo sapiens calcium/calmodulin-depend... 110 9e-24
D43636-1|BAA07744.2| 766|Homo sapiens KIAA0096 protein. 110 9e-24
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 110 9e-24
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 110 9e-24
BC021269-1|AAH21269.2| 453|Homo sapiens CAMK2G protein protein. 110 9e-24
AL713896-4|CAI13789.1| 495|Homo sapiens calcium/calmodulin-depe... 110 9e-24
AL713896-3|CAI13790.1| 529|Homo sapiens calcium/calmodulin-depe... 110 9e-24
AL713896-1|CAI13787.1| 453|Homo sapiens calcium/calmodulin-depe... 110 9e-24
AL596247-4|CAI13966.1| 495|Homo sapiens calcium/calmodulin-depe... 110 9e-24
AL596247-3|CAI13965.1| 529|Homo sapiens calcium/calmodulin-depe... 110 9e-24
AL596247-1|CAI13964.1| 453|Homo sapiens calcium/calmodulin-depe... 110 9e-24
X85545-1|CAA59733.1| 358|Homo sapiens protein kinase protein. 110 1e-23
BT020098-1|AAV38901.1| 367|Homo sapiens serum/glucocorticoid re... 110 1e-23
BC041073-1|AAH41073.1| 358|Homo sapiens protein kinase, X-linke... 110 1e-23
BC031231-1|AAH31231.1| 514|Homo sapiens serine/threonine kinase... 110 1e-23
AK093251-1|BAC04109.1| 514|Homo sapiens protein ( Homo sapiens ... 110 1e-23
AJ303380-1|CAC29064.1| 514|Homo sapiens serine/threonine kinase... 110 1e-23
AF226044-1|AAF86944.1| 765|Homo sapiens HSNFRK protein. 110 1e-23
Y15801-1|CAA75792.1| 277|Homo sapiens protein kinase protein. 109 2e-23
Y13927-1|CAA74244.1| 277|Homo sapiens protein kinase protein. 109 2e-23
BC074852-1|AAH74852.1| 277|Homo sapiens protein kinase, Y-linke... 109 2e-23
BC074851-1|AAH74851.1| 277|Homo sapiens protein kinase, Y-linke... 109 2e-23
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 109 2e-23
Z98752-8|CAI42315.1| 366|Homo sapiens serum/glucocorticoid regu... 109 2e-23
Z98752-7|CAC18509.1| 367|Homo sapiens serum/glucocorticoid regu... 109 2e-23
Z98752-5|CAI42312.1| 427|Homo sapiens serum/glucocorticoid regu... 109 2e-23
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 109 2e-23
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 109 2e-23
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 109 2e-23
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 109 2e-23
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 109 2e-23
BC065511-1|AAH65511.1| 367|Homo sapiens SGK2 protein protein. 109 2e-23
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 109 2e-23
BC014037-1|AAH14037.3| 367|Homo sapiens serum/glucocorticoid re... 109 2e-23
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 109 2e-23
AF186470-1|AAG17012.1| 427|Homo sapiens protein kinase protein. 109 2e-23
AF169034-1|AAF12757.2| 367|Homo sapiens protein kinase protein. 109 2e-23
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 109 2e-23
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 109 3e-23
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 109 3e-23
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 109 3e-23
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 109 3e-23
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 109 3e-23
Z84486-1|CAI21678.1| 526|Homo sapiens serum/glucocorticoid regu... 108 4e-23
Y10032-1|CAA71138.1| 431|Homo sapiens serine/threonine protein ... 108 4e-23
X80590-1|CAA56681.1| 387|Homo sapiens phosphorylase kinase prot... 108 4e-23
BC074753-1|AAH74753.1| 387|Homo sapiens phosphorylase kinase, g... 108 4e-23
BC069754-1|AAH69754.1| 387|Homo sapiens phosphorylase kinase, g... 108 4e-23
BC069738-1|AAH69738.1| 387|Homo sapiens phosphorylase kinase, g... 108 4e-23
BC069679-1|AAH69679.1| 387|Homo sapiens phosphorylase kinase, g... 108 4e-23
BC069655-1|AAH69655.1| 390|Homo sapiens PHKG1 protein protein. 108 4e-23
BC051327-1|AAH51327.1| 387|Homo sapiens phosphorylase kinase, g... 108 4e-23
BC001263-1|AAH01263.1| 431|Homo sapiens serum/glucocorticoid re... 108 4e-23
AL355881-2|CAH72579.1| 526|Homo sapiens serum/glucocorticoid re... 108 4e-23
AL135839-4|CAI19721.1| 526|Homo sapiens serum/glucocorticoid re... 108 4e-23
AL135839-3|CAI19720.1| 445|Homo sapiens serum/glucocorticoid re... 108 4e-23
AL135839-2|CAI19719.1| 431|Homo sapiens serum/glucocorticoid re... 108 4e-23
AL135839-1|CAI19718.1| 421|Homo sapiens serum/glucocorticoid re... 108 4e-23
AJ000512-1|CAA04146.1| 431|Homo sapiens serine/threonine protei... 108 4e-23
AF254253-1|AAL36972.1| 387|Homo sapiens phosphorylase kinase ga... 108 4e-23
AF153609-1|AAD41091.1| 431|Homo sapiens serine/threonine protei... 108 4e-23
AC092101-3|AAS07453.1| 387|Homo sapiens unknown protein. 108 4e-23
BC071567-1|AAH71567.1| 765|Homo sapiens SNRK protein protein. 108 5e-23
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 108 5e-23
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 108 5e-23
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 108 5e-23
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 108 5e-23
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 108 5e-23
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 108 5e-23
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 108 5e-23
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 108 5e-23
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 108 5e-23
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 108 5e-23
BC022515-1|AAH22515.1| 367|Homo sapiens testis-specific serine ... 107 8e-23
AY028964-1|AAK27734.1| 367|Homo sapiens testis-specific serine/... 107 8e-23
AB284522-1|BAF41973.1| 367|Homo sapiens testis-specific serine ... 107 8e-23
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 106 2e-22
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 106 2e-22
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 106 2e-22
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 106 2e-22
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 106 2e-22
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 106 2e-22
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 106 2e-22
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 106 2e-22
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 106 2e-22
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 106 2e-22
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 106 2e-22
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 106 2e-22
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 106 2e-22
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 106 2e-22
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 106 2e-22
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 106 2e-22
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 106 2e-22
AB067488-1|BAB67794.1| 1265|Homo sapiens KIAA1901 protein protein. 106 2e-22
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 105 2e-22
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 105 2e-22
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 105 2e-22
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 105 3e-22
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 105 3e-22
BC040457-1|AAH40457.1| 478|Homo sapiens calcium/calmodulin-depe... 105 3e-22
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 105 3e-22
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 105 3e-22
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 105 3e-22
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 105 3e-22
BC017187-1|AAH17187.1| 549|Homo sapiens ribosomal protein S6 ki... 105 4e-22
AF090421-1|AAC69577.1| 809|Homo sapiens ribosome S6 protein kin... 105 4e-22
AF080000-1|AAD23915.1| 802|Homo sapiens RSK-like protein kinase... 105 4e-22
AF074393-1|AAC31171.1| 802|Homo sapiens nuclear mitogen- and st... 105 4e-22
BC047896-1|AAH47896.1| 524|Homo sapiens RPS6KA4 protein protein. 104 6e-22
BC028079-1|AAH28079.1| 556|Homo sapiens Unknown (protein for IM... 104 6e-22
AK223561-1|BAD97281.1| 765|Homo sapiens ribosomal protein S6 ki... 104 6e-22
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 104 6e-22
AJ010119-1|CAA09009.1| 772|Homo sapiens Ribosomal protein kinas... 104 6e-22
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 104 6e-22
AF074715-1|AAC67395.1| 705|Homo sapiens mitogen- and stress-act... 104 6e-22
AF045458-1|AAC32326.1| 1050|Homo sapiens serine/threonine kinase... 104 6e-22
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 104 6e-22
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 104 6e-22
AB018265-1|BAA34442.2| 1066|Homo sapiens KIAA0722 protein protein. 104 6e-22
AB011446-1|BAA82709.1| 343|Homo sapiens Aik2 protein. 104 6e-22
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 104 8e-22
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 104 8e-22
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 104 8e-22
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 104 8e-22
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 104 8e-22
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 104 8e-22
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 104 8e-22
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 104 8e-22
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 103 1e-21
AF145711-1|AAD30559.1| 489|Homo sapiens calcium/calmodulin-depe... 103 1e-21
AF145710-1|AAD30558.1| 478|Homo sapiens calcium/calmodulin-depe... 103 1e-21
AF091486-1|AAD55815.1| 478|Homo sapiens calmodulin-dependent pr... 103 1e-21
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 103 1e-21
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 103 1e-21
AB023185-1|BAA76812.1| 527|Homo sapiens KIAA0968 protein protein. 103 1e-21
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 103 1e-21
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 103 1e-21
AF112472-1|AAD03744.1| 542|Homo sapiens calcium/calmodulin-depe... 103 1e-21
AF112471-1|AAD03743.1| 517|Homo sapiens calcium/calmodulin-depe... 103 1e-21
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 103 1e-21
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 103 1e-21
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 103 2e-21
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 103 2e-21
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 103 2e-21
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 103 2e-21
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 103 2e-21
BC032709-1|AAH32709.1| 344|Homo sapiens Unknown (protein for IM... 103 2e-21
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 103 2e-21
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 103 2e-21
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 103 2e-21
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 103 2e-21
U23460-1|AAC99802.1| 664|Homo sapiens proline rich calmodulin-d... 102 2e-21
BC019070-1|AAH19070.1| 503|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AK222703-1|BAD96423.1| 542|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AJ252238-1|CAB65122.1| 518|Homo sapiens calcium/calmodulin depe... 102 2e-21
AJ252237-1|CAB65121.1| 479|Homo sapiens calcium/calmodulin depe... 102 2e-21
AJ252236-1|CAB65120.1| 503|Homo sapiens calcium/calmodulin depe... 102 2e-21
AF140350-1|AAD42070.1| 449|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AF083419-1|AAD42038.1| 517|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AF081924-1|AAD42037.1| 492|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AF081572-1|AAD42036.1| 503|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AF078803-1|AAD42035.1| 542|Homo sapiens calcium/calmodulin-depe... 102 2e-21
AB209475-1|BAD92712.1| 461|Homo sapiens protein kinase C, alpha... 102 2e-21
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 102 3e-21
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 102 3e-21
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 102 3e-21
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 102 3e-21
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 102 3e-21
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 102 3e-21
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 102 3e-21
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 102 3e-21
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 101 4e-21
M14503-1|AAA36518.1| 145|Homo sapiens protein ( Human protein-s... 101 4e-21
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 101 4e-21
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 101 4e-21
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 101 4e-21
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 101 4e-21
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 101 4e-21
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 101 4e-21
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 101 4e-21
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 101 4e-21
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 101 4e-21
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 101 4e-21
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 101 4e-21
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 101 4e-21
Z29066-1|CAA82309.1| 445|Homo sapiens protein kinase protein. 101 7e-21
U11050-1|AAA19558.1| 445|Homo sapiens NIMA-like protein kinase ... 101 7e-21
BT019729-1|AAV38534.1| 445|Homo sapiens NIMA (never in mitosis ... 101 7e-21
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 101 7e-21
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 101 7e-21
BC064422-1|AAH64422.1| 241|Homo sapiens PNCK protein protein. 101 7e-21
BC052807-1|AAH52807.1| 326|Homo sapiens NEK2 protein protein. 101 7e-21
BC043502-1|AAH43502.2| 445|Homo sapiens NIMA (never in mitosis ... 101 7e-21
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 101 7e-21
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 101 7e-21
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 101 7e-21
AY045701-1|AAK92212.1| 384|Homo sapiens NEK2B protein kinase pr... 101 7e-21
AL356310-2|CAH72901.1| 445|Homo sapiens NIMA (never in mitosis ... 101 7e-21
AK223353-1|BAD97073.1| 445|Homo sapiens NIMA (never in mitosis ... 101 7e-21
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 101 7e-21
AB062450-1|BAB85632.1| 302|Homo sapiens NEK7 protein. 101 7e-21
U63333-1|AAB05809.1| 433|Homo sapiens serine/threonine protein ... 100 9e-21
BC065755-1|AAH65755.1| 234|Homo sapiens MAP3K2 protein protein. 100 9e-21
BC026060-1|AAH26060.1| 541|Homo sapiens calcium/calmodulin-depe... 100 9e-21
BC019334-1|AAH19334.1| 433|Homo sapiens serine/threonine kinase... 100 9e-21
BC007981-1|AAH07981.1| 433|Homo sapiens serine/threonine kinase... 100 9e-21
AL834322-1|CAD38990.1| 365|Homo sapiens hypothetical protein pr... 100 9e-21
AF321402-1|AAK91829.1| 588|Homo sapiens Ca2+/calmodulin-depende... 100 9e-21
AF321401-1|AAK91830.1| 533|Homo sapiens Ca2+/calmodulin-depende... 100 9e-21
AF321387-1|AAL37217.1| 541|Homo sapiens CaMKK beta 1 isoform pr... 100 9e-21
AF287631-1|AAK64601.1| 533|Homo sapiens calcium/calmodulin-depe... 100 9e-21
AF287630-1|AAK64600.1| 588|Homo sapiens calcium/calmodulin-depe... 100 9e-21
AF217978-1|AAG17221.1| 433|Homo sapiens unknown protein. 100 9e-21
AF101264-1|AAD04566.1| 417|Homo sapiens Ca2+/calmodulin-depende... 100 9e-21
AF055327-1|AAC15742.1| 433|Homo sapiens Peutz-Jeghers syndrome ... 100 9e-21
AF035625-1|AAC39527.1| 433|Homo sapiens serine threonine kinase... 100 9e-21
AF032986-1|AAB97833.1| 433|Homo sapiens serine threonine kinase... 100 9e-21
AB081336-1|BAC19840.1| 541|Homo sapiens Ca2+/calmodulin-depende... 100 9e-21
AB018330-1|BAA34507.2| 557|Homo sapiens KIAA0787 protein protein. 100 9e-21
CR456418-1|CAG30304.1| 586|Homo sapiens CHEK2 protein. 100 1e-20
BC004207-1|AAH04207.1| 543|Homo sapiens CHK2 checkpoint homolog... 100 1e-20
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 100 1e-20
AY800241-1|AAV41895.1| 543|Homo sapiens CHK2 checkpoint homolog... 100 1e-20
AY551303-1|AAS58464.1| 452|Homo sapiens protein kinase Chk2 tra... 100 1e-20
AY551297-1|AAS58458.1| 586|Homo sapiens protein kinase Chk2 tra... 100 1e-20
AL121825-1|CAH73823.1| 543|Homo sapiens CHK2 checkpoint homolog... 100 1e-20
>X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 532 bits (1313), Expect = e-151
Identities = 250/460 (54%), Positives = 335/460 (72%), Gaps = 7/460 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+ELHKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 139 LELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
++EY+GERK+TLCGTPNYIAPE+L+KKGHSFEVD+WS+GCIMYTLLVGKPPFETS LK+
Sbjct: 199 TKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE 258
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSC 180
TY RIK+ EY IP + AAS+I LQ++P RP++++LL EFF+SG +PA LP++C
Sbjct: 259 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITC 318
Query: 181 LTTAPRTDQLEGML--VHRRPLNEVHANEQETMAVDSPVKREATPAGPRAVEPTSHRQNF 238
LT PR L +R+PL ++ + + + P ++E H +
Sbjct: 319 LTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLP-ERPREKEEPVVRETGEVVDCHLSDM 377
Query: 239 IALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGV 298
+ QL ++ +K R +E DPA P+ WV KWVDYSDKYG GYQLCD SVGV
Sbjct: 378 L---QQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGV 434
Query: 299 MFNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAG 358
+FND+T+LI+ +G ++ YI R G E Y+T+ +P L KK+ LL YFR YM+EHL+KAG
Sbjct: 435 LFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAG 494
Query: 359 ASVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQIN-FQDHTKIILCPLMQAVTYID 417
A++ RE D L+RLP+L WFRT A+I++L+NG++QIN FQDHTK+ILCPLM AVTYID
Sbjct: 495 ANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYID 554
Query: 418 IEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKLNSVLANK 457
+++FRT+R + +EE+GC K+L + L YA ++ +L+++
Sbjct: 555 EKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 594
>U01038-1|AAA56634.1| 603|Homo sapiens pLK protein.
Length = 603
Score = 532 bits (1313), Expect = e-151
Identities = 250/460 (54%), Positives = 335/460 (72%), Gaps = 7/460 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+ELHKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 139 LELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
++EY+GERK+TLCGTPNYIAPE+L+KKGHSFEVD+WS+GCIMYTLLVGKPPFETS LK+
Sbjct: 199 TKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE 258
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSC 180
TY RIK+ EY IP + AAS+I LQ++P RP++++LL EFF+SG +PA LP++C
Sbjct: 259 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITC 318
Query: 181 LTTAPRTDQLEGML--VHRRPLNEVHANEQETMAVDSPVKREATPAGPRAVEPTSHRQNF 238
LT PR L +R+PL ++ + + + P ++E H +
Sbjct: 319 LTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLP-ERPREKEEPVVRETGEVVDCHLSDM 377
Query: 239 IALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGV 298
+ QL ++ +K R +E DPA P+ WV KWVDYSDKYG GYQLCD SVGV
Sbjct: 378 L---QQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGV 434
Query: 299 MFNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAG 358
+FND+T+LI+ +G ++ YI R G E Y+T+ +P L KK+ LL YFR YM+EHL+KAG
Sbjct: 435 LFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAG 494
Query: 359 ASVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQIN-FQDHTKIILCPLMQAVTYID 417
A++ RE D L+RLP+L WFRT A+I++L+NG++QIN FQDHTK+ILCPLM AVTYID
Sbjct: 495 ANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYID 554
Query: 418 IEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKLNSVLANK 457
+++FRT+R + +EE+GC K+L + L YA ++ +L+++
Sbjct: 555 EKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 594
>BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 532 bits (1313), Expect = e-151
Identities = 250/460 (54%), Positives = 335/460 (72%), Gaps = 7/460 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+ELHKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 139 LELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
++EY+GERK+TLCGTPNYIAPE+L+KKGHSFEVD+WS+GCIMYTLLVGKPPFETS LK+
Sbjct: 199 TKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE 258
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSC 180
TY RIK+ EY IP + AAS+I LQ++P RP++++LL EFF+SG +PA LP++C
Sbjct: 259 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITC 318
Query: 181 LTTAPRTDQLEGML--VHRRPLNEVHANEQETMAVDSPVKREATPAGPRAVEPTSHRQNF 238
LT PR L +R+PL ++ + + + P ++E H +
Sbjct: 319 LTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLP-ERPREKEEPVVRETGEVVDCHLSDM 377
Query: 239 IALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGV 298
+ QL ++ +K R +E DPA P+ WV KWVDYSDKYG GYQLCD SVGV
Sbjct: 378 L---QQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGV 434
Query: 299 MFNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAG 358
+FND+T+LI+ +G ++ YI R G E Y+T+ +P L KK+ LL YFR YM+EHL+KAG
Sbjct: 435 LFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAG 494
Query: 359 ASVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQIN-FQDHTKIILCPLMQAVTYID 417
A++ RE D L+RLP+L WFRT A+I++L+NG++QIN FQDHTK+ILCPLM AVTYID
Sbjct: 495 ANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYID 554
Query: 418 IEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKLNSVLANK 457
+++FRT+R + +EE+GC K+L + L YA ++ +L+++
Sbjct: 555 EKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 594
>BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 532 bits (1313), Expect = e-151
Identities = 250/460 (54%), Positives = 335/460 (72%), Gaps = 7/460 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+ELHKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 139 LELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
++EY+GERK+TLCGTPNYIAPE+L+KKGHSFEVD+WS+GCIMYTLLVGKPPFETS LK+
Sbjct: 199 TKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE 258
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSC 180
TY RIK+ EY IP + AAS+I LQ++P RP++++LL EFF+SG +PA LP++C
Sbjct: 259 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITC 318
Query: 181 LTTAPRTDQLEGML--VHRRPLNEVHANEQETMAVDSPVKREATPAGPRAVEPTSHRQNF 238
LT PR L +R+PL ++ + + + P ++E H +
Sbjct: 319 LTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLP-ERPREKEEPVVRETGEVVDCHLSDM 377
Query: 239 IALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGV 298
+ QL ++ +K R +E DPA P+ WV KWVDYSDKYG GYQLCD SVGV
Sbjct: 378 L---QQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGV 434
Query: 299 MFNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAG 358
+FND+T+LI+ +G ++ YI R G E Y+T+ +P L KK+ LL YFR YM+EHL+KAG
Sbjct: 435 LFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAG 494
Query: 359 ASVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQIN-FQDHTKIILCPLMQAVTYID 417
A++ RE D L+RLP+L WFRT A+I++L+NG++QIN FQDHTK+ILCPLM AVTYID
Sbjct: 495 ANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYID 554
Query: 418 IEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKLNSVLANK 457
+++FRT+R + +EE+GC K+L + L YA ++ +L+++
Sbjct: 555 EKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 594
>BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 532 bits (1313), Expect = e-151
Identities = 250/460 (54%), Positives = 335/460 (72%), Gaps = 7/460 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+ELHKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 139 LELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
++EY+GERK+TLCGTPNYIAPE+L+KKGHSFEVD+WS+GCIMYTLLVGKPPFETS LK+
Sbjct: 199 TKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE 258
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSC 180
TY RIK+ EY IP + AAS+I LQ++P RP++++LL EFF+SG +PA LP++C
Sbjct: 259 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITC 318
Query: 181 LTTAPRTDQLEGML--VHRRPLNEVHANEQETMAVDSPVKREATPAGPRAVEPTSHRQNF 238
LT PR L +R+PL ++ + + + P ++E H +
Sbjct: 319 LTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLP-ERPREKEEPVVRETGEVVDCHLSDM 377
Query: 239 IALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGV 298
+ QL ++ +K R +E DPA P+ WV KWVDYSDKYG GYQLCD SVGV
Sbjct: 378 L---QQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGV 434
Query: 299 MFNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAG 358
+FND+T+LI+ +G ++ YI R G E Y+T+ +P L KK+ LL YFR YM+EHL+KAG
Sbjct: 435 LFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAG 494
Query: 359 ASVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQIN-FQDHTKIILCPLMQAVTYID 417
A++ RE D L+RLP+L WFRT A+I++L+NG++QIN FQDHTK+ILCPLM AVTYID
Sbjct: 495 ANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYID 554
Query: 418 IEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKLNSVLANK 457
+++FRT+R + +EE+GC K+L + L YA ++ +L+++
Sbjct: 555 EKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 594
>AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase variant
protein.
Length = 546
Score = 532 bits (1313), Expect = e-151
Identities = 250/460 (54%), Positives = 335/460 (72%), Gaps = 7/460 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+ELHKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 82 LELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 141
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
++EY+GERK+TLCGTPNYIAPE+L+KKGHSFEVD+WS+GCIMYTLLVGKPPFETS LK+
Sbjct: 142 TKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE 201
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSC 180
TY RIK+ EY IP + AAS+I LQ++P RP++++LL EFF+SG +PA LP++C
Sbjct: 202 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITC 261
Query: 181 LTTAPRTDQLEGML--VHRRPLNEVHANEQETMAVDSPVKREATPAGPRAVEPTSHRQNF 238
LT PR L +R+PL ++ + + + P ++E H +
Sbjct: 262 LTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLP-ERPREKEEPVVRETGEVVDCHLSDM 320
Query: 239 IALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGV 298
+ QL ++ +K R +E DPA P+ WV KWVDYSDKYG GYQLCD SVGV
Sbjct: 321 L---QQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGV 377
Query: 299 MFNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAG 358
+FND+T+LI+ +G ++ YI R G E Y+T+ +P L KK+ LL YFR YM+EHL+KAG
Sbjct: 378 LFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAG 437
Query: 359 ASVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQIN-FQDHTKIILCPLMQAVTYID 417
A++ RE D L+RLP+L WFRT A+I++L+NG++QIN FQDHTK+ILCPLM AVTYID
Sbjct: 438 ANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYID 497
Query: 418 IEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKLNSVLANK 457
+++FRT+R + +EE+GC K+L + L YA ++ +L+++
Sbjct: 498 EKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 537
>L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 528 bits (1304), Expect = e-149
Identities = 248/460 (53%), Positives = 334/460 (72%), Gaps = 7/460 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+ELHKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 139 LELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
++EY+GERK+TLCGTPNYIAPE+L+KKGHSFEVD+WS+GCIMYTLLVGKPPFETS LK+
Sbjct: 199 TKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE 258
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSC 180
TY RIK+ EY IP + AAS+I LQ++P RP++++LL EFF+SG +PA LP++C
Sbjct: 259 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLGDEFFTSGYIPARLPITC 318
Query: 181 LTTAPRTDQLEGML--VHRRPLNEVHANEQETMAVDSPVKREATPAGPRAVEPTSHRQNF 238
LT PR L +R+PL ++ + + + P ++E H +
Sbjct: 319 LTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLP-ERPREKEEPVVRETGEVVDCHLSDM 377
Query: 239 IALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGV 298
+ QL ++ +K R +E DPA P+ WV KWVDYSDKYG GYQLCD SVGV
Sbjct: 378 L---QQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGV 434
Query: 299 MFNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAG 358
+FND+T+LI+ +G ++ YI R G E Y+T+ +P L KK+ LL YFR YM+EHL+KAG
Sbjct: 435 LFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAG 494
Query: 359 ASVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQIN-FQDHTKIILCPLMQAVTYID 417
++ R+ D L+RLP+L WFRT A+I++L+NG++QIN FQDHTK+ILCPLM AVTYID
Sbjct: 495 GNITPRQGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYID 554
Query: 418 IEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKLNSVLANK 457
+++FRT+R + +EE+GC K+L + L YA ++ +L+++
Sbjct: 555 EKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 594
>X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein
kinase protein.
Length = 603
Score = 526 bits (1298), Expect = e-149
Identities = 248/460 (53%), Positives = 333/460 (72%), Gaps = 7/460 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+E HKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 139 LEPHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
++EY+GERK+TLCGTPNYIAPE+L+KK HSFEVD+WS+GCIMYTLLVGKPPFETS LK+
Sbjct: 199 TKVEYDGERKKTLCGTPNYIAPEVLSKKEHSFEVDVWSIGCIMYTLLVGKPPFETSCLKE 258
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSC 180
TY RIK+ EY IP + AAS+I LQ++P RP++++LL EFF+SG +PA LP++C
Sbjct: 259 TYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITC 318
Query: 181 LTTAPRTDQLEGML--VHRRPLNEVHANEQETMAVDSPVKREATPAGPRAVEPTSHRQNF 238
LT PR L +R+PL ++ + + + P ++E H +
Sbjct: 319 LTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLP-ERPREKEEPVVRETGEVVDCHLSDM 377
Query: 239 IALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGV 298
+ QL ++ +K R +E DPA P+ WV KWVDYSDKYG GYQLCD SVGV
Sbjct: 378 L---QQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGV 434
Query: 299 MFNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAG 358
+FND+T+LI+ +G ++ YI R G E Y+T+ +P L KK+ LL YFR YM+EHL+KAG
Sbjct: 435 LFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAG 494
Query: 359 ASVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQIN-FQDHTKIILCPLMQAVTYID 417
A++ RE D L+RLP+L WFRT A+I++L+NG++QIN FQDHTK+ILCPLM AVTYID
Sbjct: 495 ANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYID 554
Query: 418 IEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKLNSVLANK 457
+++FRT+R + +EE+GC K+L + L YA ++ +L+++
Sbjct: 555 EKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSR 594
>U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine
protein kinase PRK protein.
Length = 607
Score = 230 bits (563), Expect = 7e-60
Identities = 95/176 (53%), Positives = 135/176 (76%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ EPE R+Y+ QIL G++YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +R
Sbjct: 118 LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQR 177
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
K+T+CGTPNY+APE+L ++GH E D+WSLGC+MYTLL G PPFET+ LK+TY+ IKQ
Sbjct: 178 KKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVH 237
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTAP 185
Y +P+SL PA ++ L+++P RPS+D++L+H+FF+ G P LP+S T P
Sbjct: 238 YTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVP 293
Score = 136 bits (328), Expect = 2e-31
Identities = 74/185 (40%), Positives = 107/185 (57%), Gaps = 7/185 (3%)
Query: 270 QPLVWVGKWVDYSDKYGFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQEQYMTM 329
+PLVWV KWVDYS+K+GFGYQL V V+FND T + + AN VHY + ++
Sbjct: 420 EPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSV 479
Query: 330 RDYPQELDKKMKLLTYFRRYMTEHLMKAGASVPVRESDGLSRLPHLHQWFRTTLAVIMYL 389
P+ L ++ +L YF YM +HLMK G +P E + P L QW +T A++M
Sbjct: 480 GAVPRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEVEVPAPPLLLQWVKTDQALLMLF 538
Query: 390 TNGTLQINFQ-DHTKIILC---PLMQAVTYIDIEKNFRTFRFNTIEEHGCDKKLYTNLTY 445
++GT+Q+NF DHTK+IL PL+ VT++ ++ T+ + + + GC L L Y
Sbjct: 539 SDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPDLRQRLRY 596
Query: 446 ALEKL 450
AL L
Sbjct: 597 ALRLL 601
>BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 230 bits (563), Expect = 7e-60
Identities = 95/176 (53%), Positives = 135/176 (76%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ EPE R+Y+ QIL G++YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +R
Sbjct: 157 LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQR 216
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
K+T+CGTPNY+APE+L ++GH E D+WSLGC+MYTLL G PPFET+ LK+TY+ IKQ
Sbjct: 217 KKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVH 276
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTAP 185
Y +P+SL PA ++ L+++P RPS+D++L+H+FF+ G P LP+S T P
Sbjct: 277 YTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVP 332
Score = 134 bits (323), Expect = 8e-31
Identities = 73/185 (39%), Positives = 107/185 (57%), Gaps = 7/185 (3%)
Query: 270 QPLVWVGKWVDYSDKYGFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQEQYMTM 329
+PLVWV KWVDYS+K+GFGYQL V V+FN+ T + + AN VHY + ++
Sbjct: 459 EPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNNGTHMALSANRKTVHYNPTSTKHFSFSV 518
Query: 330 RDYPQELDKKMKLLTYFRRYMTEHLMKAGASVPVRESDGLSRLPHLHQWFRTTLAVIMYL 389
P+ L ++ +L YF YM +HLMK G +P E + P L QW +T A++M
Sbjct: 519 GAVPRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEVEVPAPPLLLQWVKTDQALLMLF 577
Query: 390 TNGTLQINFQ-DHTKIILC---PLMQAVTYIDIEKNFRTFRFNTIEEHGCDKKLYTNLTY 445
++GT+Q+NF DHTK+IL PL+ VT++ ++ T+ + + + GC L L Y
Sbjct: 578 SDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPDLRQRLRY 635
Query: 446 ALEKL 450
AL L
Sbjct: 636 ALRLL 640
>AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 230 bits (563), Expect = 7e-60
Identities = 95/176 (53%), Positives = 135/176 (76%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ EPE R+Y+ QIL G++YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +R
Sbjct: 157 LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQR 216
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
K+T+CGTPNY+APE+L ++GH E D+WSLGC+MYTLL G PPFET+ LK+TY+ IKQ
Sbjct: 217 KKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVH 276
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTAP 185
Y +P+SL PA ++ L+++P RPS+D++L+H+FF+ G P LP+S T P
Sbjct: 277 YTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVP 332
Score = 136 bits (328), Expect = 2e-31
Identities = 74/185 (40%), Positives = 107/185 (57%), Gaps = 7/185 (3%)
Query: 270 QPLVWVGKWVDYSDKYGFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQEQYMTM 329
+PLVWV KWVDYS+K+GFGYQL V V+FND T + + AN VHY + ++
Sbjct: 459 EPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSV 518
Query: 330 RDYPQELDKKMKLLTYFRRYMTEHLMKAGASVPVRESDGLSRLPHLHQWFRTTLAVIMYL 389
P+ L ++ +L YF YM +HLMK G +P E + P L QW +T A++M
Sbjct: 519 GAVPRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEVEVPAPPLLLQWVKTDQALLMLF 577
Query: 390 TNGTLQINFQ-DHTKIILC---PLMQAVTYIDIEKNFRTFRFNTIEEHGCDKKLYTNLTY 445
++GT+Q+NF DHTK+IL PL+ VT++ ++ T+ + + + GC L L Y
Sbjct: 578 SDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPDLRQRLRY 635
Query: 446 ALEKL 450
AL L
Sbjct: 636 ALRLL 640
>AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3
(Drosophila) protein.
Length = 646
Score = 230 bits (563), Expect = 7e-60
Identities = 95/176 (53%), Positives = 135/176 (76%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ EPE R+Y+ QIL G++YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +R
Sbjct: 157 LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQR 216
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
K+T+CGTPNY+APE+L ++GH E D+WSLGC+MYTLL G PPFET+ LK+TY+ IKQ
Sbjct: 217 KKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVH 276
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTAP 185
Y +P+SL PA ++ L+++P RPS+D++L+H+FF+ G P LP+S T P
Sbjct: 277 YTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVP 332
Score = 136 bits (328), Expect = 2e-31
Identities = 74/185 (40%), Positives = 107/185 (57%), Gaps = 7/185 (3%)
Query: 270 QPLVWVGKWVDYSDKYGFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQEQYMTM 329
+PLVWV KWVDYS+K+GFGYQL V V+FND T + + AN VHY + ++
Sbjct: 459 EPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSV 518
Query: 330 RDYPQELDKKMKLLTYFRRYMTEHLMKAGASVPVRESDGLSRLPHLHQWFRTTLAVIMYL 389
P+ L ++ +L YF YM +HLMK G +P E + P L QW +T A++M
Sbjct: 519 GAVPRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEVEVPAPPLLLQWVKTDQALLMLF 577
Query: 390 TNGTLQINFQ-DHTKIILC---PLMQAVTYIDIEKNFRTFRFNTIEEHGCDKKLYTNLTY 445
++GT+Q+NF DHTK+IL PL+ VT++ ++ T+ + + + GC L L Y
Sbjct: 578 SDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPDLRQRLRY 635
Query: 446 ALEKL 450
AL L
Sbjct: 636 ALRLL 640
>AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine
protein kinase protein.
Length = 646
Score = 230 bits (563), Expect = 7e-60
Identities = 95/176 (53%), Positives = 135/176 (76%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ EPE R+Y+ QIL G++YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +R
Sbjct: 157 LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQR 216
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
K+T+CGTPNY+APE+L ++GH E D+WSLGC+MYTLL G PPFET+ LK+TY+ IKQ
Sbjct: 217 KKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVH 276
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTAP 185
Y +P+SL PA ++ L+++P RPS+D++L+H+FF+ G P LP+S T P
Sbjct: 277 YTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVP 332
Score = 124 bits (299), Expect = 7e-28
Identities = 69/185 (37%), Positives = 104/185 (56%), Gaps = 7/185 (3%)
Query: 270 QPLVWVGKWVDYSDKYGFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQEQYMTM 329
+PLVW +WV +S+K+GFGYQL V V+FND T + + AN VHY + ++
Sbjct: 459 EPLVWFSEWVGFSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSV 518
Query: 330 RDYPQELDKKMKLLTYFRRYMTEHLMKAGASVPVRESDGLSRLPHLHQWFRTTLAVIMYL 389
+ L ++ +L YF YM +HLMK G +P E + P L QW +T A++M
Sbjct: 519 GAVRRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEVEVPAPPLLLQWVKTDQALLMLF 577
Query: 390 TNGTLQINFQ-DHTKIILC---PLMQAVTYIDIEKNFRTFRFNTIEEHGCDKKLYTNLTY 445
++GT+Q+NF DHTK+IL PL+ VT++ ++ T+ + + + GC L L Y
Sbjct: 578 SDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPDLRQRLRY 635
Query: 446 ALEKL 450
AL L
Sbjct: 636 ALRLL 640
>AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 variant
protein.
Length = 621
Score = 230 bits (563), Expect = 7e-60
Identities = 95/176 (53%), Positives = 135/176 (76%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ EPE R+Y+ QIL G++YLH + I+HRDLKLGN F+ +++ +K+GDFGLAAR+E +R
Sbjct: 132 LLEPEVRYYLRQILSGLKYLHQRGILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQR 191
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
K+T+CGTPNY+APE+L ++GH E D+WSLGC+MYTLL G PPFET+ LK+TY+ IKQ
Sbjct: 192 KKTICGTPNYVAPEVLLRQGHGPEADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVH 251
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTAP 185
Y +P+SL PA ++ L+++P RPS+D++L+H+FF+ G P LP+S T P
Sbjct: 252 YTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPISSCVTVP 307
Score = 136 bits (328), Expect = 2e-31
Identities = 74/185 (40%), Positives = 107/185 (57%), Gaps = 7/185 (3%)
Query: 270 QPLVWVGKWVDYSDKYGFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQEQYMTM 329
+PLVWV KWVDYS+K+GFGYQL V V+FND T + + AN VHY + ++
Sbjct: 434 EPLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSV 493
Query: 330 RDYPQELDKKMKLLTYFRRYMTEHLMKAGASVPVRESDGLSRLPHLHQWFRTTLAVIMYL 389
P+ L ++ +L YF YM +HLMK G +P E + P L QW +T A++M
Sbjct: 494 GAVPRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEVEVPAPPLLLQWVKTDQALLMLF 552
Query: 390 TNGTLQINFQ-DHTKIILC---PLMQAVTYIDIEKNFRTFRFNTIEEHGCDKKLYTNLTY 445
++GT+Q+NF DHTK+IL PL+ VT++ ++ T+ + + + GC L L Y
Sbjct: 553 SDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPDLRQRLRY 610
Query: 446 ALEKL 450
AL L
Sbjct: 611 ALRLL 615
>U85755-1|AAD00575.1| 299|Homo sapiens serum-inducible kinase
protein.
Length = 299
Score = 227 bits (556), Expect = 5e-59
Identities = 95/181 (52%), Positives = 134/181 (74%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
K K +TEPE R+Y+ QI+ G++YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E
Sbjct: 63 KARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLE 122
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R++T+CGTPNY++PE+L K+GH E DIW+LGC+MYT+L+G+PPFET+ LK+TY+
Sbjct: 123 PLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRC 182
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTA 184
I++ Y +PSSL PA +I L NP RPS+D +++H+FF G P L SC T
Sbjct: 183 IREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTV 242
Query: 185 P 185
P
Sbjct: 243 P 243
>BC013879-1|AAH13879.1| 685|Homo sapiens polo-like kinase 2
(Drosophila) protein.
Length = 685
Score = 227 bits (556), Expect = 5e-59
Identities = 95/181 (52%), Positives = 134/181 (74%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
K K +TEPE R+Y+ QI+ G++YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E
Sbjct: 172 KARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLE 231
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R++T+CGTPNY++PE+L K+GH E DIW+LGC+MYT+L+G+PPFET+ LK+TY+
Sbjct: 232 PLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRC 291
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTA 184
I++ Y +PSSL PA +I L NP RPS+D +++H+FF G P L SC T
Sbjct: 292 IREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTV 351
Query: 185 P 185
P
Sbjct: 352 P 352
Score = 138 bits (335), Expect = 3e-32
Identities = 80/214 (37%), Positives = 117/214 (54%), Gaps = 6/214 (2%)
Query: 240 ALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGVM 299
++ D +A +L L+ PEA + + WV KWVDYS+KYGFGYQL D +VGV+
Sbjct: 470 SVADTVARVLRGCLENMPEADCIP-KEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVL 528
Query: 300 FNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAGA 359
FN+ + +L + VHY GQ D P++ ++ +L YF YM E+LM G
Sbjct: 529 FNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMD-GG 587
Query: 360 SVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQINF-QDHTKIILCPLMQ--AVTYI 416
+P RL +L QW ++ A++M +GT Q+NF DHTKII+C + +TYI
Sbjct: 588 DLPSVTDIRRPRL-YLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYI 646
Query: 417 DIEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKL 450
+ ++ TFR T+ GC +L + YAL L
Sbjct: 647 NEDRISTTFRLTTLLMSGCSSELKNRMEYALNML 680
>AK098163-1|BAC05247.1| 372|Homo sapiens protein ( Homo sapiens
cDNA FLJ40844 fis, clone TRACH2014356, highly similar to
SERINE/THREONINE-PROTEIN KINASE SNK (EC 2.7.1.-). ).
Length = 372
Score = 227 bits (556), Expect = 5e-59
Identities = 95/181 (52%), Positives = 134/181 (74%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
K K +TEPE R+Y+ QI+ G++YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E
Sbjct: 165 KARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLE 224
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R++T+CGTPNY++PE+L K+GH E DIW+LGC+MYT+L+G+PPFET+ LK+TY+
Sbjct: 225 PLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRC 284
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTA 184
I++ Y +PSSL PA +I L NP RPS+D +++H+FF G P L SC T
Sbjct: 285 IREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTV 344
Query: 185 P 185
P
Sbjct: 345 P 345
>AF223574-1|AAF62897.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 227 bits (556), Expect = 5e-59
Identities = 95/181 (52%), Positives = 134/181 (74%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
K K +TEPE R+Y+ QI+ G++YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E
Sbjct: 172 KARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLE 231
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R++T+CGTPNY++PE+L K+GH E DIW+LGC+MYT+L+G+PPFET+ LK+TY+
Sbjct: 232 PLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRC 291
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTA 184
I++ Y +PSSL PA +I L NP RPS+D +++H+FF G P L SC T
Sbjct: 292 IREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTV 351
Query: 185 P 185
P
Sbjct: 352 P 352
Score = 138 bits (335), Expect = 3e-32
Identities = 80/214 (37%), Positives = 117/214 (54%), Gaps = 6/214 (2%)
Query: 240 ALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGVM 299
++ D +A +L L+ PEA + + WV KWVDYS+KYGFGYQL D +VGV+
Sbjct: 470 SVADTVARVLRGCLENMPEADCIP-KEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVL 528
Query: 300 FNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAGA 359
FN+ + +L + VHY GQ D P++ ++ +L YF YM E+LM G
Sbjct: 529 FNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMD-GG 587
Query: 360 SVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQINF-QDHTKIILCPLMQ--AVTYI 416
+P RL +L QW ++ A++M +GT Q+NF DHTKII+C + +TYI
Sbjct: 588 DLPSVTDIRRPRL-YLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYI 646
Query: 417 DIEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKL 450
+ ++ TFR T+ GC +L + YAL L
Sbjct: 647 NEDRISTTFRLTTLLMSGCSSELKNRMEYALNML 680
>AF059617-1|AAC14573.1| 685|Homo sapiens serum-inducible kinase
protein.
Length = 685
Score = 227 bits (556), Expect = 5e-59
Identities = 95/181 (52%), Positives = 134/181 (74%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
K K +TEPE R+Y+ QI+ G++YLH + I+HRDLKLGN F+++ + +K+GDFGLAAR+E
Sbjct: 172 KARKVLTEPEVRYYLRQIVSGLKYLHEQEILHRDLKLGNFFINEAMELKVGDFGLAARLE 231
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R++T+CGTPNY++PE+L K+GH E DIW+LGC+MYT+L+G+PPFET+ LK+TY+
Sbjct: 232 PLEHRRRTICGTPNYLSPEVLNKQGHGCESDIWALGCVMYTMLLGRPPFETTNLKETYRC 291
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLTTA 184
I++ Y +PSSL PA +I L NP RPS+D +++H+FF G P L SC T
Sbjct: 292 IREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTV 351
Query: 185 P 185
P
Sbjct: 352 P 352
Score = 138 bits (335), Expect = 3e-32
Identities = 80/214 (37%), Positives = 117/214 (54%), Gaps = 6/214 (2%)
Query: 240 ALRDQLAALLVNKLKCRPEALTDELSDPAAQPLVWVGKWVDYSDKYGFGYQLCDESVGVM 299
++ D +A +L L+ PEA + + WV KWVDYS+KYGFGYQL D +VGV+
Sbjct: 470 SVADTVARVLRGCLENMPEADCIP-KEQLSTSFQWVTKWVDYSNKYGFGYQLSDHTVGVL 528
Query: 300 FNDTTKLIMLANGLNVHYINRQGQEQYMTMRDYPQELDKKMKLLTYFRRYMTEHLMKAGA 359
FN+ + +L + VHY GQ D P++ ++ +L YF YM E+LM G
Sbjct: 529 FNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMD-GG 587
Query: 360 SVPVRESDGLSRLPHLHQWFRTTLAVIMYLTNGTLQINF-QDHTKIILCPLMQ--AVTYI 416
+P RL +L QW ++ A++M +GT Q+NF DHTKII+C + +TYI
Sbjct: 588 DLPSVTDIRRPRL-YLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYI 646
Query: 417 DIEKNFRTFRFNTIEEHGCDKKLYTNLTYALEKL 450
+ ++ TFR T+ GC +L + YAL L
Sbjct: 647 NEDRISTTFRLTTLLMSGCSSELKNRMEYALNML 680
>BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4
(Drosophila) protein.
Length = 970
Score = 182 bits (443), Expect = 2e-45
Identities = 81/166 (48%), Positives = 112/166 (67%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
L R+K +E E R +MHQI+ G+ YLHS I+HRDL L NL L ++++KI DFGLA +
Sbjct: 101 LKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQ 160
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
++ E+ TLCGTPNYI+PEI T+ H E D+WSLGC+ YTLL+G+PPF+T T+K+T
Sbjct: 161 LKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTL 220
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFS 168
++ +Y +PS L A +I L+ NPA R S+ +L H F S
Sbjct: 221 NKVVLADYEMPSFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMS 266
Score = 31.1 bits (67), Expect = 8.5
Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 286 GFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQ-EQYMTMRDYPQELDKKMKLLT 344
G+ QL +V V FND ++L++ A ++ Y + GQ +Y P + +K++ L+
Sbjct: 897 GWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLS 956
>Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein
kinase protein.
Length = 970
Score = 181 bits (440), Expect = 5e-45
Identities = 80/166 (48%), Positives = 112/166 (67%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
L R+K +E E R +MHQI+ G+ YLHS I+HRDL L NL L ++++KI DFGLA +
Sbjct: 101 LKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQ 160
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
++ E+ TLCGTPNYI+PEI T+ H E D+WSLGC+ YTLL+G+PPF+T T+K+T
Sbjct: 161 LKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTL 220
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFS 168
++ +Y +P+ L A +I L+ NPA R S+ +L H F S
Sbjct: 221 NKVVLADYEMPTFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMS 266
Score = 31.1 bits (67), Expect = 8.5
Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 286 GFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQ-EQYMTMRDYPQELDKKMKLLT 344
G+ QL +V V FND ++L++ A ++ Y + GQ +Y P + +K++ L+
Sbjct: 897 GWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLS 956
>AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein.
Length = 970
Score = 181 bits (440), Expect = 5e-45
Identities = 80/166 (48%), Positives = 112/166 (67%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
L R+K +E E R +MHQI+ G+ YLHS I+HRDL L NL L ++++KI DFGLA +
Sbjct: 101 LKNRVKPFSENEARHFMHQIITGMLYLHSHGILHRDLTLSNLLLTRNMNIKIADFGLATQ 160
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
++ E+ TLCGTPNYI+PEI T+ H E D+WSLGC+ YTLL+G+PPF+T T+K+T
Sbjct: 161 LKMPHEKHYTLCGTPNYISPEIATRSAHGLESDVWSLGCMFYTLLIGRPPFDTDTVKNTL 220
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFS 168
++ +Y +P+ L A +I L+ NPA R S+ +L H F S
Sbjct: 221 NKVVLADYEMPTFLSIEAKDLIHQLLRRNPADRLSLSSVLDHPFMS 266
Score = 31.1 bits (67), Expect = 8.5
Identities = 17/60 (28%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 286 GFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQ-EQYMTMRDYPQELDKKMKLLT 344
G+ QL +V V FND ++L++ A ++ Y + GQ +Y P + +K++ L+
Sbjct: 897 GWATQLTSGAVWVQFNDGSQLVVQAGVSSISYTSPNGQTTRYGENEKLPDYIKQKLQCLS 956
>AK131198-1|BAD18393.1| 706|Homo sapiens protein ( Homo sapiens
cDNA FLJ16039 fis, clone ADRGL2001554, weakly similar
to SERINE/THREONINE-PROTEIN KINASE PLK (EC 2.7.1.-). ).
Length = 706
Score = 170 bits (414), Expect = 8e-42
Identities = 82/182 (45%), Positives = 124/182 (68%), Gaps = 8/182 (4%)
Query: 8 KAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEG 67
+ +TEPE ++++ QI+ V YLH + IIHRDLKLGN+FLD++L VK+GD GLAA++
Sbjct: 132 ECLTEPEVQYFLLQIIDAVSYLHKRCIIHRDLKLGNIFLDENLEVKVGDLGLAAQLNEPN 191
Query: 68 ERKQTLCGTPNYIAPEIL---TKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
ERK+T+CGTPNYIAPEIL K+ +S+EVDIW++G I YT+L+GK PF+ + + TY++
Sbjct: 192 ERKKTMCGTPNYIAPEILQSNDKRAYSYEVDIWAVGVITYTMLIGKAPFDGGSKEITYRK 251
Query: 125 IKQCEYRIP---SSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGIL--PAGLPVS 179
I++ E P + A I L +P +R ++++++QH FF+ + P LP+
Sbjct: 252 IRENELSFPIKDHHISHQARMFIRSILNPDPTQRLTLEQMVQHPFFTDSPIDPPKSLPLY 311
Query: 180 CL 181
L
Sbjct: 312 IL 313
Score = 69.7 bits (163), Expect = 2e-11
Identities = 46/159 (28%), Positives = 75/159 (47%), Gaps = 15/159 (9%)
Query: 274 WVGKWVDYSDKYGFGYQLCDESVGVMFNDTTKLIMLANGLNVHYINRQGQEQYM------ 327
W+ D++ KYG GY + ++G++FND T +++ A+G+ Y R Q+
Sbjct: 504 WIVDEYDFTRKYGIGYMFSNGNIGILFNDKTSIVLSADGMFFEYHPRISITQWNAKQTFP 563
Query: 328 -----TMRDYPQELDKKMKLLTYFR---RYMTEHLMKAGASVPVRESDGLS-RLPHLHQW 378
++ DYP EL KK+ L+ YFR R E+ M + V G +P +W
Sbjct: 564 PSVSGSIDDYPDELAKKITLIKYFRTNFRDRAENRMLSKEEVEDTARGGPKVNMPFALKW 623
Query: 379 FRTTLAVIMYLTNGTLQINFQDHTKIILCPLMQAVTYID 417
+ A I L+ G +Q+ + T + L VTY+D
Sbjct: 624 LKKEDASICMLSTGAIQVRYDGGTILNLESPFDDVTYLD 662
>AB084459-1|BAD93352.1| 247|Homo sapiens polo-like kinase 1 delta
protein.
Length = 247
Score = 146 bits (353), Expect = 2e-34
Identities = 62/84 (73%), Positives = 75/84 (89%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
+ELHKR KA+TEPE R+Y+ QI+LG QYLH R+IHRDLKLGNLFL++DL VKIGDFGLA
Sbjct: 139 LELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLA 198
Query: 61 ARIEYEGERKQTLCGTPNYIAPEI 84
++EY+GERK+TLCGTPNYIAP +
Sbjct: 199 TKVEYDGERKKTLCGTPNYIAPAV 222
>BC027464-1|AAH27464.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 138 bits (333), Expect = 5e-32
Identities = 63/165 (38%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 341 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>BC006423-1|AAH06423.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 138 bits (333), Expect = 5e-32
Identities = 63/165 (38%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 341 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>BC002499-1|AAH02499.1| 403|Homo sapiens AURKA protein protein.
Length = 403
Score = 138 bits (333), Expect = 5e-32
Identities = 63/165 (38%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 341 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>BC001280-1|AAH01280.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 138 bits (333), Expect = 5e-32
Identities = 63/165 (38%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 341 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>AL121914-3|CAC12717.1| 403|Homo sapiens aurora kinase A protein.
Length = 403
Score = 138 bits (333), Expect = 5e-32
Identities = 63/165 (38%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 341 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>AF195947-1|AAF29508.1| 403|Homo sapiens STK15 serine/threonine
kinase protein.
Length = 403
Score = 138 bits (333), Expect = 5e-32
Identities = 63/165 (38%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 341 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>AF011468-1|AAC63902.1| 403|Homo sapiens serine/threonine kinase
protein.
Length = 403
Score = 138 bits (333), Expect = 5e-32
Identities = 63/165 (38%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 341 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>AF008551-1|AAC12708.1| 403|Homo sapiens aurora-related kinase 1
protein.
Length = 403
Score = 138 bits (333), Expect = 5e-32
Identities = 63/165 (38%), Positives = 102/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 341 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 385
>D84212-1|BAA23592.1| 402|Homo sapiens aurora/IPL1-related kinase
protein.
Length = 402
Score = 135 bits (326), Expect = 4e-31
Identities = 63/165 (38%), Positives = 101/165 (61%), Gaps = 2/165 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T ++I + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 222 QKLSKFDEQRTANLYNRIANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 279
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 280 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 339
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
I + E+ P + + A +I L+ NP++RP + ++L+H + ++
Sbjct: 340 ISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITA 384
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 130 bits (315), Expect = 8e-30
Identities = 67/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H KRI+HRDLK NL LD D+++KI DFG +
Sbjct: 147 HGRMK---EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF 203
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 204 TVGG-KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 262
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R +++++++ + ++G
Sbjct: 263 ERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG 310
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 130 bits (315), Expect = 8e-30
Identities = 67/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H KRI+HRDLK NL LD D+++KI DFG +
Sbjct: 147 HGRMK---EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF 203
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 204 TVGG-KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 262
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R +++++++ + ++G
Sbjct: 263 ERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG 310
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 130 bits (315), Expect = 8e-30
Identities = 67/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H KRI+HRDLK NL LD D+++KI DFG +
Sbjct: 147 HGRMK---EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF 203
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 204 TVGG-KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 262
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R +++++++ + ++G
Sbjct: 263 ERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG 310
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 130 bits (315), Expect = 8e-30
Identities = 67/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H KRI+HRDLK NL LD D+++KI DFG +
Sbjct: 147 HGRMK---EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF 203
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 204 TVGG-KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 262
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R +++++++ + ++G
Sbjct: 263 ERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG 310
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 130 bits (315), Expect = 8e-30
Identities = 67/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H KRI+HRDLK NL LD D+++KI DFG +
Sbjct: 147 HGRMK---EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEF 203
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 204 TVGG-KLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 262
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R +++++++ + ++G
Sbjct: 263 ERVLRGKYRIPFYMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAG 310
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 129 bits (312), Expect = 2e-29
Identities = 67/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 151 HGRMK---EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 207
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 208 TV-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 266
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R S++++++ + + G
Sbjct: 267 ERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVG 314
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 129 bits (312), Expect = 2e-29
Identities = 67/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 151 HGRMK---EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 207
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 208 TV-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 266
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R S++++++ + + G
Sbjct: 267 ERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVG 314
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 129 bits (312), Expect = 2e-29
Identities = 67/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 151 HGRMK---EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 207
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 208 TV-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 266
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R S++++++ + + G
Sbjct: 267 ERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVG 314
>AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 758
Score = 129 bits (312), Expect = 2e-29
Identities = 67/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 129 HGRMK---EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 185
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 186 TV-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 244
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R S++++++ + + G
Sbjct: 245 ERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVG 292
>AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens
cDNA FLJ14587 fis, clone NT2RM4001758, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK
(EC 2.7.1.-). ).
Length = 638
Score = 129 bits (312), Expect = 2e-29
Identities = 67/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 16 HGRMK---EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 72
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 73 TV-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 131
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R S++++++ + + G
Sbjct: 132 ERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVG 179
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 129 bits (312), Expect = 2e-29
Identities = 67/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 151 HGRMK---EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 207
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 208 TV-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 266
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R S++++++ + + G
Sbjct: 267 ERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVG 314
>AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein.
Length = 870
Score = 129 bits (312), Expect = 2e-29
Identities = 67/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 241 HGRMK---EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEF 297
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 298 TV-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 356
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP +R S++++++ + + G
Sbjct: 357 ERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRGSLEQIMKDRWMNVG 404
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 129 bits (311), Expect = 2e-29
Identities = 66/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 111 HGRMK---EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF 167
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 168 TF-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 226
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP++R +++++++ + + G
Sbjct: 227 ERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVG 274
>U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein.
Length = 984
Score = 129 bits (311), Expect = 2e-29
Identities = 63/153 (41%), Positives = 89/153 (58%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
+H +EP FY ++LG+QYLH +I++RDLKL NL LD + VKI DFGL
Sbjct: 747 MHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKE 806
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT+ ++ VD W LG ++Y +LVG+ PF ++ +
Sbjct: 807 GMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVF 866
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A S++ L+ NP RR
Sbjct: 867 DSIVNDEVRYPRFLSTEAISIMRRLLRRNPERR 899
>S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein.
Length = 984
Score = 129 bits (311), Expect = 2e-29
Identities = 63/153 (41%), Positives = 89/153 (58%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
+H +EP FY ++LG+QYLH +I++RDLKL NL LD + VKI DFGL
Sbjct: 747 MHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKE 806
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT+ ++ VD W LG ++Y +LVG+ PF ++ +
Sbjct: 807 GMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVF 866
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A S++ L+ NP RR
Sbjct: 867 DSIVNDEVRYPRFLSTEAISIMRRLLRRNPERR 899
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 129 bits (311), Expect = 2e-29
Identities = 66/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 111 HGRMK---EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF 167
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 168 TF-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 226
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP++R +++++++ + + G
Sbjct: 227 ERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVG 274
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 129 bits (311), Expect = 2e-29
Identities = 66/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 144 HGRMK---EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF 200
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 201 TF-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 259
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP++R +++++++ + + G
Sbjct: 260 ERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVG 307
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 129 bits (311), Expect = 2e-29
Identities = 66/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 134 HGRMK---EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF 190
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 191 TF-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 249
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP++R +++++++ + + G
Sbjct: 250 ERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVG 297
>AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein.
Length = 984
Score = 129 bits (311), Expect = 2e-29
Identities = 63/153 (41%), Positives = 89/153 (58%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
+H +EP FY ++LG+QYLH +I++RDLKL NL LD + VKI DFGL
Sbjct: 747 MHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGFVKIADFGLCKE 806
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT+ ++ VD W LG ++Y +LVG+ PF ++ +
Sbjct: 807 GMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVF 866
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A S++ L+ NP RR
Sbjct: 867 DSIVNDEVRYPRFLSTEAISIMRRLLRRNPERR 899
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 129 bits (311), Expect = 2e-29
Identities = 66/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 111 HGRMK---EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF 167
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 168 TF-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 226
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP++R +++++++ + + G
Sbjct: 227 ERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVG 274
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 129 bits (311), Expect = 2e-29
Identities = 66/168 (39%), Positives = 101/168 (60%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ VQY H K I+HRDLK NL LD D+++KI DFG +
Sbjct: 144 HGRMK---EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEF 200
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ G + T CG+P Y APE+ KK EVD+WSLG I+YTL+ G PF+ LK+
Sbjct: 201 TF-GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELR 259
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YRIP + +++ L NP++R +++++++ + + G
Sbjct: 260 ERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVG 307
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 128 bits (309), Expect = 4e-29
Identities = 62/163 (38%), Positives = 99/163 (60%), Gaps = 2/163 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++HRDLK N+ LD ++ KI DFGL+ + +GE
Sbjct: 111 VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGEF 169
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I+
Sbjct: 170 LRTSCGSPNYTAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG 229
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ IP L + A++++ LQ +P +R ++ + +HE+F G+
Sbjct: 230 VFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQGL 272
>BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein.
Length = 936
Score = 128 bits (309), Expect = 4e-29
Identities = 63/153 (41%), Positives = 89/153 (58%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
+H +EP FY ++LG+QYLH +I++RDLKL NL LD + VKI DFGL
Sbjct: 699 MHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVYRDLKLDNLLLDTEGLVKIADFGLCKE 758
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT+ ++ VD W LG ++Y +LVG+ PF ++ +
Sbjct: 759 GMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDWWGLGVLIYEMLVGESPFPGDDEEEVF 818
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A S++ L+ NP RR
Sbjct: 819 DSIVNDEVRYPRFLSTEAISIMRRLLRRNPERR 851
>U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein.
Length = 942
Score = 127 bits (306), Expect = 9e-29
Identities = 62/153 (40%), Positives = 88/153 (57%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
LH +EP FY ++LG+Q+LH +I++RDLKL NL LD + +VKI DFGL
Sbjct: 705 LHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKE 764
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT ++ VD W LG ++Y +LVG+ PF ++ +
Sbjct: 765 GMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVF 824
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A ++ L+ NP RR
Sbjct: 825 DSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERR 857
>S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein.
Length = 942
Score = 127 bits (306), Expect = 9e-29
Identities = 62/153 (40%), Positives = 88/153 (57%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
LH +EP FY ++LG+Q+LH +I++RDLKL NL LD + +VKI DFGL
Sbjct: 705 LHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKE 764
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT ++ VD W LG ++Y +LVG+ PF ++ +
Sbjct: 765 GMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVF 824
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A ++ L+ NP RR
Sbjct: 825 DSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERR 857
>D26181-1|BAA05169.1| 942|Homo sapiens PKN protein.
Length = 942
Score = 127 bits (306), Expect = 9e-29
Identities = 62/153 (40%), Positives = 88/153 (57%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
LH +EP FY ++LG+Q+LH +I++RDLKL NL LD + +VKI DFGL
Sbjct: 705 LHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKE 764
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT ++ VD W LG ++Y +LVG+ PF ++ +
Sbjct: 765 GMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVF 824
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A ++ L+ NP RR
Sbjct: 825 DSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERR 857
>BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein.
Length = 942
Score = 127 bits (306), Expect = 9e-29
Identities = 62/153 (40%), Positives = 88/153 (57%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
LH +EP FY ++LG+Q+LH +I++RDLKL NL LD + +VKI DFGL
Sbjct: 705 LHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKE 764
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT ++ VD W LG ++Y +LVG+ PF ++ +
Sbjct: 765 GMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVF 824
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A ++ L+ NP RR
Sbjct: 825 DSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERR 857
>M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine
kinase protein.
Length = 481
Score = 126 bits (305), Expect = 1e-28
Identities = 64/169 (37%), Positives = 97/169 (57%), Gaps = 5/169 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + TE RFY +I+ ++YLHS+ +++RD+KL NL LD D H+KI DFGL
Sbjct: 243 RERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGIS 302
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+G +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 303 DGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELI 362
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR----PS-VDKLLQHEFFSS 169
E R P +L A S++ L+ +P +R PS ++++H FF S
Sbjct: 363 LMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLS 411
>M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta
protein.
Length = 520
Score = 126 bits (305), Expect = 1e-28
Identities = 64/169 (37%), Positives = 97/169 (57%), Gaps = 5/169 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + TE RFY +I+ ++YLHS+ +++RD+KL NL LD D H+KI DFGL
Sbjct: 243 RERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGIS 302
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+G +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 303 DGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELI 362
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR----PS-VDKLLQHEFFSS 169
E R P +L A S++ L+ +P +R PS ++++H FF S
Sbjct: 363 LMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLS 411
>BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma viral
oncogene homolog 2 protein.
Length = 481
Score = 126 bits (305), Expect = 1e-28
Identities = 64/169 (37%), Positives = 97/169 (57%), Gaps = 5/169 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + TE RFY +I+ ++YLHS+ +++RD+KL NL LD D H+KI DFGL
Sbjct: 243 RERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGIS 302
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+G +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 303 DGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELI 362
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR----PS-VDKLLQHEFFSS 169
E R P +L A S++ L+ +P +R PS ++++H FF S
Sbjct: 363 LMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLS 411
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 125 bits (302), Expect = 3e-28
Identities = 61/163 (37%), Positives = 98/163 (60%), Gaps = 2/163 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++HRDLK N+ LD ++ KI DFGL+ + +GE
Sbjct: 111 VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGEF 169
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I+
Sbjct: 170 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG 229
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ IP L + A++++ LQ +P +R ++ + +HE+F +
Sbjct: 230 VFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDL 272
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 125 bits (302), Expect = 3e-28
Identities = 61/163 (37%), Positives = 98/163 (60%), Gaps = 2/163 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++HRDLK N+ LD ++ KI DFGL+ + +GE
Sbjct: 111 VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGEF 169
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I+
Sbjct: 170 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG 229
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ IP L + A++++ LQ +P +R ++ + +HE+F +
Sbjct: 230 VFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDL 272
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 125 bits (302), Expect = 3e-28
Identities = 61/163 (37%), Positives = 98/163 (60%), Gaps = 2/163 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++HRDLK N+ LD ++ KI DFGL+ + +GE
Sbjct: 111 VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGEF 169
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I+
Sbjct: 170 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG 229
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ IP L + A++++ LQ +P +R ++ + +HE+F +
Sbjct: 230 VFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDL 272
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 125 bits (302), Expect = 3e-28
Identities = 61/163 (37%), Positives = 98/163 (60%), Gaps = 2/163 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++HRDLK N+ LD ++ KI DFGL+ + +GE
Sbjct: 111 VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGEF 169
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I+
Sbjct: 170 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG 229
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ IP L + A++++ LQ +P +R ++ + +HE+F +
Sbjct: 230 VFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDL 272
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 125 bits (302), Expect = 3e-28
Identities = 66/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ V Y H K I+HRDLK NL LD + ++KI DFG +
Sbjct: 150 HGRMK---EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF 206
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVDIWSLG I+YTL+ G PF+ LK+
Sbjct: 207 TL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELR 265
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YR+P + S++ L NPA+R +++++++ ++ + G
Sbjct: 266 ERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIG 313
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 125 bits (302), Expect = 3e-28
Identities = 66/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ V Y H K I+HRDLK NL LD + ++KI DFG +
Sbjct: 150 HGRMK---EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF 206
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVDIWSLG I+YTL+ G PF+ LK+
Sbjct: 207 TL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELR 265
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YR+P + S++ L NPA+R +++++++ ++ + G
Sbjct: 266 ERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIG 313
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 125 bits (302), Expect = 3e-28
Identities = 61/163 (37%), Positives = 98/163 (60%), Gaps = 2/163 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++HRDLK N+ LD ++ KI DFGL+ + +GE
Sbjct: 111 VEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGEF 169
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I+
Sbjct: 170 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTLPFDDEHVPTLFKKIRGG 229
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ IP L + A++++ LQ +P +R ++ + +HE+F +
Sbjct: 230 VFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIREHEWFKQDL 272
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 125 bits (302), Expect = 3e-28
Identities = 66/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ V Y H K I+HRDLK NL LD + ++KI DFG +
Sbjct: 150 HGRMK---EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF 206
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVDIWSLG I+YTL+ G PF+ LK+
Sbjct: 207 TL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELR 265
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YR+P + S++ L NPA+R +++++++ ++ + G
Sbjct: 266 ERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIG 313
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 125 bits (302), Expect = 3e-28
Identities = 66/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ V Y H K I+HRDLK NL LD + ++KI DFG +
Sbjct: 16 HGRMK---EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF 72
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVDIWSLG I+YTL+ G PF+ LK+
Sbjct: 73 TL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELR 131
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YR+P + S++ L NPA+R +++++++ ++ + G
Sbjct: 132 ERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIG 179
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 125 bits (302), Expect = 3e-28
Identities = 66/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ V Y H K I+HRDLK NL LD + ++KI DFG +
Sbjct: 180 HGRMK---EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF 236
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVDIWSLG I+YTL+ G PF+ LK+
Sbjct: 237 TL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELR 295
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YR+P + S++ L NPA+R +++++++ ++ + G
Sbjct: 296 ERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIG 343
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 125 bits (302), Expect = 3e-28
Identities = 66/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ V Y H K I+HRDLK NL LD + ++KI DFG +
Sbjct: 150 HGRMK---EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF 206
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVDIWSLG I+YTL+ G PF+ LK+
Sbjct: 207 TL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELR 265
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YR+P + S++ L NPA+R +++++++ ++ + G
Sbjct: 266 ERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIG 313
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 125 bits (302), Expect = 3e-28
Identities = 66/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ V Y H K I+HRDLK NL LD + ++KI DFG +
Sbjct: 151 HGRMK---EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF 207
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVDIWSLG I+YTL+ G PF+ LK+
Sbjct: 208 TL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELR 266
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YR+P + S++ L NPA+R +++++++ ++ + G
Sbjct: 267 ERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIG 314
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 125 bits (302), Expect = 3e-28
Identities = 66/168 (39%), Positives = 99/168 (58%), Gaps = 5/168 (2%)
Query: 4 HKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARI 63
H R+K E E R QI+ V Y H K I+HRDLK NL LD + ++KI DFG +
Sbjct: 150 HGRMK---EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEF 206
Query: 64 EYEGERKQTLCGTPNYIAPEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G + T CG+P Y APE+ KK EVDIWSLG I+YTL+ G PF+ LK+
Sbjct: 207 TL-GSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELR 265
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+R+ + +YR+P + S++ L NPA+R +++++++ ++ + G
Sbjct: 266 ERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIG 313
>AB019692-1|BAA85625.1| 889|Homo sapiens protein kinase PKNbeta
protein.
Length = 889
Score = 125 bits (302), Expect = 3e-28
Identities = 62/155 (40%), Positives = 93/155 (60%), Gaps = 2/155 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
M++H+ + EP+ RFY+ ++LG+Q+LH K+II+RDLKL NL LD +KI DFGL
Sbjct: 649 MQIHEDV--FPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLC 706
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
G+R T CGTP ++APE+LT++ ++ VD W+LG ++Y +LVG+ PF T ++
Sbjct: 707 KEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTQAVDWWALGVLLYEMLVGECPFPGDTEEE 766
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
+ I + P L I LQ P +R
Sbjct: 767 VFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKR 801
>BC062558-1|AAH62558.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 125 bits (301), Expect = 4e-28
Identities = 62/155 (40%), Positives = 92/155 (59%), Gaps = 2/155 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
M++H+ + EP+ RFY+ ++LG+Q+LH K+II+RDLKL NL LD +KI DFGL
Sbjct: 649 MQIHEDV--FPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLC 706
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
G+R T CGTP ++APE+LT++ ++ VD W LG ++Y +LVG+ PF T ++
Sbjct: 707 KEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEE 766
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
+ I + P L I LQ P +R
Sbjct: 767 VFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKR 801
>AL441992-1|CAI15401.1| 889|Homo sapiens protein kinase N3 protein.
Length = 889
Score = 125 bits (301), Expect = 4e-28
Identities = 62/155 (40%), Positives = 92/155 (59%), Gaps = 2/155 (1%)
Query: 1 MELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA 60
M++H+ + EP+ RFY+ ++LG+Q+LH K+II+RDLKL NL LD +KI DFGL
Sbjct: 649 MQIHEDV--FPEPQARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLC 706
Query: 61 ARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKD 120
G+R T CGTP ++APE+LT++ ++ VD W LG ++Y +LVG+ PF T ++
Sbjct: 707 KEGIGFGDRTSTFCGTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEE 766
Query: 121 TYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
+ I + P L I LQ P +R
Sbjct: 767 VFDCIVNMDAPYPGFLSVQGLEFIQKLLQKCPEKR 801
>X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein
kinase protein.
Length = 479
Score = 124 bits (300), Expect = 5e-28
Identities = 61/153 (39%), Positives = 87/153 (56%)
Query: 3 LHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR 62
LH +EP FY ++LG+Q+LH +I++RDLKL NL LD + +VKI DFGL
Sbjct: 242 LHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKE 301
Query: 63 IEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
G+R T CGTP ++APE+LT ++ VD W LG ++Y +LVG+ P ++ +
Sbjct: 302 GMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPLPGDDEEEVF 361
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E R P L A ++ L+ NP RR
Sbjct: 362 DSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERR 394
>AF159295-1|AAD48007.1| 752|Homo sapiens serine/threonine protein
kinase Kp78 splice variant CTAK75a protein.
Length = 752
Score = 124 bits (298), Expect = 9e-28
Identities = 60/150 (40%), Positives = 93/150 (62%), Gaps = 2/150 (1%)
Query: 22 ILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGTPNYIA 81
I+ VQY H KRI+HRDLK NL LD D+++KI DFG + G + T CG+P Y A
Sbjct: 185 IVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGG-KLDTFCGSPPYAA 243
Query: 82 PEILT-KKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSLRKPA 140
PE+ KK EVD+WSLG I+YTL+ G PF+ LK+ +R+ + +YRIP +
Sbjct: 244 PELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDC 303
Query: 141 ASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
+++ L NP +R +++++++ + ++G
Sbjct: 304 ENLLKRFLVLNPIKRGTLEQIMKDRWINAG 333
>X52479-1|CAA36718.1| 672|Homo sapiens protein ( Human PKC alpha
mRNA for protein kinase C alpha. ).
Length = 672
Score = 123 bits (297), Expect = 1e-27
Identities = 56/151 (37%), Positives = 90/151 (59%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP+ FY +I +G+ +LH + II+RDLKL N+ LD + H+KI DFG+
Sbjct: 430 QQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM 489
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+PPF+ + ++
Sbjct: 490 MDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQS 549
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + P SL K A S+ + +PA+R
Sbjct: 550 IMEHNVSYPKSLSKEAVSICKGLMTKHPAKR 580
>BC109274-1|AAI09275.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 123 bits (297), Expect = 1e-27
Identities = 56/151 (37%), Positives = 90/151 (59%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP+ FY +I +G+ +LH + II+RDLKL N+ LD + H+KI DFG+
Sbjct: 430 QQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM 489
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+PPF+ + ++
Sbjct: 490 MDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQS 549
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + P SL K A S+ + +PA+R
Sbjct: 550 IMEHNVSYPKSLSKEAVSICKGLMTKHPAKR 580
>BC109273-1|AAI09274.1| 672|Homo sapiens protein kinase C, alpha
protein.
Length = 672
Score = 123 bits (297), Expect = 1e-27
Identities = 56/151 (37%), Positives = 90/151 (59%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP+ FY +I +G+ +LH + II+RDLKL N+ LD + H+KI DFG+
Sbjct: 430 QQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM 489
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+PPF+ + ++
Sbjct: 490 MDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQS 549
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + P SL K A S+ + +PA+R
Sbjct: 550 IMEHNVSYPKSLSKEAVSICKGLMTKHPAKR 580
>AY633609-1|AAV33302.1| 672|Homo sapiens aging-associated gene 6
protein protein.
Length = 672
Score = 123 bits (297), Expect = 1e-27
Identities = 56/151 (37%), Positives = 90/151 (59%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP+ FY +I +G+ +LH + II+RDLKL N+ LD + H+KI DFG+
Sbjct: 430 QQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIADFGMCKEHM 489
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+PPF+ + ++
Sbjct: 490 MDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELFQS 549
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + P SL K A S+ + +PA+R
Sbjct: 550 IMEHNVSYPKSLSKEAVSVCKGLMTKHPAKR 580
>L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 122 bits (295), Expect = 2e-27
Identities = 60/152 (39%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+LG+Q+LHSK I++RDLKL N+ LD D H+KI DFG+ + T CGT
Sbjct: 483 FYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGT 542
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL + ++ VD WS G ++Y +L+G+ PF ++ + I+ P L
Sbjct: 543 PDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL 602
Query: 137 RKPAASMIVLQLQSNPARRPSV-DKLLQHEFF 167
K A ++V P +R V + QH F
Sbjct: 603 EKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
>L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 122 bits (295), Expect = 2e-27
Identities = 60/152 (39%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+LG+Q+LHSK I++RDLKL N+ LD D H+KI DFG+ + T CGT
Sbjct: 483 FYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGT 542
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL + ++ VD WS G ++Y +L+G+ PF ++ + I+ P L
Sbjct: 543 PDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL 602
Query: 137 RKPAASMIVLQLQSNPARRPSV-DKLLQHEFF 167
K A ++V P +R V + QH F
Sbjct: 603 EKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
>BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 122 bits (295), Expect = 2e-27
Identities = 60/152 (39%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+LG+Q+LHSK I++RDLKL N+ LD D H+KI DFG+ + T CGT
Sbjct: 483 FYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGT 542
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL + ++ VD WS G ++Y +L+G+ PF ++ + I+ P L
Sbjct: 543 PDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL 602
Query: 137 RKPAASMIVLQLQSNPARRPSV-DKLLQHEFF 167
K A ++V P +R V + QH F
Sbjct: 603 EKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
>BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 122 bits (295), Expect = 2e-27
Identities = 60/152 (39%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+LG+Q+LHSK I++RDLKL N+ LD D H+KI DFG+ + T CGT
Sbjct: 483 FYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGT 542
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL + ++ VD WS G ++Y +L+G+ PF ++ + I+ P L
Sbjct: 543 PDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL 602
Query: 137 RKPAASMIVLQLQSNPARRPSV-DKLLQHEFF 167
K A ++V P +R V + QH F
Sbjct: 603 EKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 122 bits (295), Expect = 2e-27
Identities = 62/165 (37%), Positives = 96/165 (58%), Gaps = 2/165 (1%)
Query: 8 KAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEG 67
K + E E+R QIL GV Y H ++HRDLK N+ LD ++ KI DFGL+ + +G
Sbjct: 135 KELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DG 193
Query: 68 ERKQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIK 126
E +T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I
Sbjct: 194 EFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKIC 253
Query: 127 QCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ P L S++ LQ +P +R ++ + +HE+F +
Sbjct: 254 DGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDL 298
>AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 122 bits (295), Expect = 2e-27
Identities = 60/152 (39%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+LG+Q+LHSK I++RDLKL N+ LD D H+KI DFG+ + T CGT
Sbjct: 483 FYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGT 542
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL + ++ VD WS G ++Y +L+G+ PF ++ + I+ P L
Sbjct: 543 PDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL 602
Query: 137 RKPAASMIVLQLQSNPARRPSV-DKLLQHEFF 167
K A ++V P +R V + QH F
Sbjct: 603 EKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
>AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 122 bits (295), Expect = 2e-27
Identities = 60/152 (39%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+LG+Q+LHSK I++RDLKL N+ LD D H+KI DFG+ + T CGT
Sbjct: 255 FYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGT 314
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL + ++ VD WS G ++Y +L+G+ PF ++ + I+ P L
Sbjct: 315 PDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL 374
Query: 137 RKPAASMIVLQLQSNPARRPSV-DKLLQHEFF 167
K A ++V P +R V + QH F
Sbjct: 375 EKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 406
>AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 122 bits (295), Expect = 2e-27
Identities = 60/152 (39%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+LG+Q+LHSK I++RDLKL N+ LD D H+KI DFG+ + T CGT
Sbjct: 483 FYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGT 542
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL + ++ VD WS G ++Y +L+G+ PF ++ + I+ P L
Sbjct: 543 PDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL 602
Query: 137 RKPAASMIVLQLQSNPARRPSV-DKLLQHEFF 167
K A ++V P +R V + QH F
Sbjct: 603 EKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 634
>AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 122 bits (295), Expect = 2e-27
Identities = 60/152 (39%), Positives = 87/152 (57%), Gaps = 1/152 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+LG+Q+LHSK I++RDLKL N+ LD D H+KI DFG+ + T CGT
Sbjct: 255 FYAAEIILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGT 314
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL + ++ VD WS G ++Y +L+G+ PF ++ + I+ P L
Sbjct: 315 PDYIAPEILLGQKYNHSVDWWSFGVLLYEMLIGQSPFHGQDEEELFHSIRMDNPFYPRWL 374
Query: 137 RKPAASMIVLQLQSNPARRPSV-DKLLQHEFF 167
K A ++V P +R V + QH F
Sbjct: 375 EKEAKDLLVKLFVREPEKRLGVRGDIRQHPLF 406
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 122 bits (294), Expect = 3e-27
Identities = 65/169 (38%), Positives = 96/169 (56%), Gaps = 11/169 (6%)
Query: 9 AITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGE 68
A++E ETR M +L V +LH+ I+HRDLK N+ LDD++ +++ DFG + +E GE
Sbjct: 124 ALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE-PGE 182
Query: 69 RKQTLCGTPNYIAPEIL------TKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ + LCGTP Y+APEIL T G+ EVD+W+ G I++TLL G PPF
Sbjct: 183 KLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILML 242
Query: 123 KRIKQCEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFF 167
+ I + +Y+ S +I LQ +P R + ++ LQH FF
Sbjct: 243 RMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFF 291
>X65293-1|CAA46388.1| 737|Homo sapiens protein kinase C epsilon
protein.
Length = 737
Score = 122 bits (294), Expect = 3e-27
Identities = 62/170 (36%), Positives = 91/170 (53%), Gaps = 7/170 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R + EP +RFY ++ + +LH +I+RDLKL N+ LD + H K+ DFG+
Sbjct: 499 QRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGI 558
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
G T CGTP+YIAPEIL + + VD W+LG +MY ++ G+PPFE D ++
Sbjct: 559 LNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFES 618
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-------PSVDKLLQHEFF 167
I + P L K A S++ + NP +R D + QH FF
Sbjct: 619 ILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFF 668
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 166 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 224
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 225 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 284
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 285 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 329
Score = 91.1 bits (216), Expect = 8e-18
Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 507 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 566
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 567 QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTP 626
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +S+ A ++ L +P +R + +L+H
Sbjct: 627 EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRH 676
>M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A
gamma-subunit protein.
Length = 360
Score = 122 bits (294), Expect = 3e-27
Identities = 61/151 (40%), Positives = 88/151 (58%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R+ +EP FY Q++L VQYLHS +IHRDLK NL +D ++++ DFG A R++
Sbjct: 143 QRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK 202
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + VG PPF Y++
Sbjct: 203 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEK 259
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I R PS L ++ LQ + +R
Sbjct: 260 IVSGRVRFPSKLSSDLKDLLRSLLQVDLTKR 290
>M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase
protein.
Length = 406
Score = 122 bits (294), Expect = 3e-27
Identities = 65/169 (38%), Positives = 96/169 (56%), Gaps = 11/169 (6%)
Query: 9 AITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGE 68
A++E ETR M +L V +LH+ I+HRDLK N+ LDD++ +++ DFG + +E GE
Sbjct: 124 ALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE-PGE 182
Query: 69 RKQTLCGTPNYIAPEIL------TKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ + LCGTP Y+APEIL T G+ EVD+W+ G I++TLL G PPF
Sbjct: 183 KLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILML 242
Query: 123 KRIKQCEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFF 167
+ I + +Y+ S +I LQ +P R + ++ LQH FF
Sbjct: 243 RMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFF 291
>L07599-1|AAC82495.1| 580|Homo sapiens ribosomal protein S6 kinase
3 protein.
Length = 580
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 165 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 223
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 224 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 283
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 284 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 328
Score = 43.6 bits (98), Expect = 0.001
Identities = 26/75 (34%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 505 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 564
Query: 62 RIEYEGERKQTLCGT 76
++ E T C T
Sbjct: 565 QLRAENGLLMTPCYT 579
>BC109034-1|AAI09035.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 122 bits (294), Expect = 3e-27
Identities = 62/170 (36%), Positives = 91/170 (53%), Gaps = 7/170 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R + EP +RFY ++ + +LH +I+RDLKL N+ LD + H K+ DFG+
Sbjct: 499 QRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGI 558
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
G T CGTP+YIAPEIL + + VD W+LG +MY ++ G+PPFE D ++
Sbjct: 559 LNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFES 618
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-------PSVDKLLQHEFF 167
I + P L K A S++ + NP +R D + QH FF
Sbjct: 619 ILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFF 668
>BC109033-1|AAI09034.1| 737|Homo sapiens protein kinase C, epsilon
protein.
Length = 737
Score = 122 bits (294), Expect = 3e-27
Identities = 62/170 (36%), Positives = 91/170 (53%), Gaps = 7/170 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R + EP +RFY ++ + +LH +I+RDLKL N+ LD + H K+ DFG+
Sbjct: 499 QRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGI 558
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
G T CGTP+YIAPEIL + + VD W+LG +MY ++ G+PPFE D ++
Sbjct: 559 LNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFES 618
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-------PSVDKLLQHEFF 167
I + P L K A S++ + NP +R D + QH FF
Sbjct: 619 ILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFF 668
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 166 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 224
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 225 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 284
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 285 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 329
Score = 91.1 bits (216), Expect = 8e-18
Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 507 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 566
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 567 QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTP 626
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +S+ A ++ L +P +R + +L+H
Sbjct: 627 EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRH 676
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 166 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 224
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 225 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 284
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 285 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 329
Score = 91.1 bits (216), Expect = 8e-18
Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 507 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 566
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 567 QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTP 626
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +S+ A ++ L +P +R + +L+H
Sbjct: 627 EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRH 676
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 166 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 224
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 225 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 284
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 285 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 329
Score = 91.1 bits (216), Expect = 8e-18
Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 507 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 566
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 567 QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTP 626
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +S+ A ++ L +P +R + +L+H
Sbjct: 627 EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRH 676
>BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase,
gamma 2 (testis) protein.
Length = 406
Score = 122 bits (294), Expect = 3e-27
Identities = 65/169 (38%), Positives = 96/169 (56%), Gaps = 11/169 (6%)
Query: 9 AITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGE 68
A++E ETR M +L V +LH+ I+HRDLK N+ LDD++ +++ DFG + +E GE
Sbjct: 124 ALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLE-PGE 182
Query: 69 RKQTLCGTPNYIAPEIL------TKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
+ + LCGTP Y+APEIL T G+ EVD+W+ G I++TLL G PPF
Sbjct: 183 KLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILML 242
Query: 123 KRIKQCEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFF 167
+ I + +Y+ S +I LQ +P R + ++ LQH FF
Sbjct: 243 RMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFF 291
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 166 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 224
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 225 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 284
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 285 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 329
Score = 91.1 bits (216), Expect = 8e-18
Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 507 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 566
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 567 QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTP 626
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +S+ A ++ L +P +R + +L+H
Sbjct: 627 EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRH 676
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 166 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 224
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 225 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 284
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 285 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 329
Score = 91.1 bits (216), Expect = 8e-18
Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 507 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 566
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 567 QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTP 626
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +S+ A ++ L +P +R + +L+H
Sbjct: 627 EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRH 676
>AC017006-1|AAX93253.1| 258|Homo sapiens unknown protein.
Length = 258
Score = 122 bits (294), Expect = 3e-27
Identities = 62/170 (36%), Positives = 91/170 (53%), Gaps = 7/170 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R + EP +RFY ++ + +LH +I+RDLKL N+ LD + H K+ DFG+
Sbjct: 20 QRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILLDAEGHCKLADFGMCKEGI 79
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
G T CGTP+YIAPEIL + + VD W+LG +MY ++ G+PPFE D ++
Sbjct: 80 LNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEMMAGQPPFEADNEDDLFES 139
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-------PSVDKLLQHEFF 167
I + P L K A S++ + NP +R D + QH FF
Sbjct: 140 ILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVASQNGEDAIKQHPFF 189
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 233 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 291
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 292 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 351
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 352 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 396
Score = 91.1 bits (216), Expect = 8e-18
Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 573 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 632
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 633 QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTP 692
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +S+ A ++ L +P +R + +L+H
Sbjct: 693 EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRH 742
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 122 bits (294), Expect = 3e-27
Identities = 59/165 (35%), Positives = 101/165 (61%), Gaps = 7/165 (4%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAAR-IEYEGER 69
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+K+ DFGL+ I++E ++
Sbjct: 152 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHE-KK 210
Query: 70 KQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCE 129
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 211 AYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAK 270
Query: 130 YRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FFS+
Sbjct: 271 LGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFST 315
Score = 91.1 bits (216), Expect = 8e-18
Identities = 54/170 (31%), Positives = 92/170 (54%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E + I V+YLH++ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 493 RQKFFSEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAK 552
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 553 QLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTP 612
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +S+ A ++ L +P +R + +L+H
Sbjct: 613 EEILARIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRH 662
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 122 bits (294), Expect = 3e-27
Identities = 62/163 (38%), Positives = 95/163 (58%), Gaps = 2/163 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E+R QIL GV Y H ++HRDLK N+ LD ++ KI DFGL+ + +GE
Sbjct: 113 LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGEF 171
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I
Sbjct: 172 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG 231
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ P L S++ LQ +P +R S+ + +HE+F +
Sbjct: 232 IFYTPQYLNPSVISLLKHMLQVDPMKRASIKDIREHEWFKQDL 274
>M63167-1|AAA36539.1| 480|Homo sapiens rac protein kinase-alpha
protein.
Length = 480
Score = 122 bits (293), Expect = 4e-27
Identities = 63/169 (37%), Positives = 94/169 (55%), Gaps = 6/169 (3%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHS-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
R + +E RFY +I+ + YLHS K +++RDLKL NL LD D H+KI DFGL
Sbjct: 241 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI 300
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++
Sbjct: 301 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL 360
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
I E R P +L A S++ L+ +P +R +++QH FF+
Sbjct: 361 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFA 409
>DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 122 bits (293), Expect = 4e-27
Identities = 61/151 (40%), Positives = 88/151 (58%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R+ +EP FY Q++L VQYLHS +IHRDLK NL +D ++++ DFG A R++
Sbjct: 134 QRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + VG PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I R PS L ++ LQ + +R
Sbjct: 251 IVSGRVRFPSKLSSDLKHLLRSLLQVDLTKR 281
>BC084538-1|AAH84538.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 122 bits (293), Expect = 4e-27
Identities = 63/169 (37%), Positives = 94/169 (55%), Gaps = 6/169 (3%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHS-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
R + +E RFY +I+ + YLHS K +++RDLKL NL LD D H+KI DFGL
Sbjct: 241 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI 300
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++
Sbjct: 301 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL 360
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
I E R P +L A S++ L+ +P +R +++QH FF+
Sbjct: 361 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFA 409
>BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 122 bits (293), Expect = 4e-27
Identities = 61/151 (40%), Positives = 88/151 (58%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R+ +EP FY Q++L VQYLHS +IHRDLK NL +D ++++ DFG A R++
Sbjct: 134 QRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + VG PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I R PS L ++ LQ + +R
Sbjct: 251 IVSGRVRFPSKLSSDLKHLLRSLLQVDLTKR 281
>BC000479-1|AAH00479.1| 480|Homo sapiens v-akt murine thymoma viral
oncogene homolog 1 protein.
Length = 480
Score = 122 bits (293), Expect = 4e-27
Identities = 63/169 (37%), Positives = 94/169 (55%), Gaps = 6/169 (3%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHS-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
R + +E RFY +I+ + YLHS K +++RDLKL NL LD D H+KI DFGL
Sbjct: 241 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI 300
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++
Sbjct: 301 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL 360
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
I E R P +L A S++ L+ +P +R +++QH FF+
Sbjct: 361 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFA 409
>AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, gamma protein.
Length = 351
Score = 122 bits (293), Expect = 4e-27
Identities = 61/151 (40%), Positives = 88/151 (58%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R+ +EP FY Q++L VQYLHS +IHRDLK NL +D ++++ DFG A R++
Sbjct: 134 QRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + VG PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I R PS L ++ LQ + +R
Sbjct: 251 IVSGRVRFPSKLSSDLKHLLRSLLQVDLTKR 281
>AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein
kinase gamma isoform protein.
Length = 351
Score = 122 bits (293), Expect = 4e-27
Identities = 61/151 (40%), Positives = 88/151 (58%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R+ +EP FY Q++L VQYLHS +IHRDLK NL +D ++++ DFG A R++
Sbjct: 134 QRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + VG PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I R PS L ++ LQ + +R
Sbjct: 251 IVSGRVRFPSKLSSDLKHLLRSLLQVDLTKR 281
>AF283830-1|AAL55732.1| 480|Homo sapiens AKT1 protein.
Length = 480
Score = 122 bits (293), Expect = 4e-27
Identities = 63/169 (37%), Positives = 94/169 (55%), Gaps = 6/169 (3%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHS-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
R + +E RFY +I+ + YLHS K +++RDLKL NL LD D H+KI DFGL
Sbjct: 241 RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI 300
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++
Sbjct: 301 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL 360
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
I E R P +L A S++ L+ +P +R +++QH FF+
Sbjct: 361 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFA 409
>X61037-1|CAA43372.1| 417|Homo sapiens human protein kinase B
protein.
Length = 417
Score = 121 bits (292), Expect = 5e-27
Identities = 63/169 (37%), Positives = 93/169 (55%), Gaps = 6/169 (3%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHS-KRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
R + E RFY +I+ + YLHS K +++RDLKL NL LD D H+KI DFGL
Sbjct: 178 RERVFAEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI 237
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+G +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++
Sbjct: 238 KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL 297
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
I E R P +L A S++ L+ +P +R +++QH FF+
Sbjct: 298 ILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFT 346
>L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 121 bits (292), Expect = 5e-27
Identities = 59/154 (38%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+ G+Q+LHSK II+RDLKL N+ LD D H+KI DFG+ + R T CGT
Sbjct: 452 FYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGT 511
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL ++F VD WS G ++Y +L+G+ PF + ++ I+ P +
Sbjct: 512 PDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 571
Query: 137 RKPAASMIVLQLQSNPARRPSVDKLLQ-HEFFSS 169
K + ++ + P +R V ++ H FF +
Sbjct: 572 TKESKDILEKLFEREPTKRLGVTGNIKIHPFFKT 605
>D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-type
protein.
Length = 626
Score = 121 bits (292), Expect = 5e-27
Identities = 59/154 (38%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+ G+Q+LHSK II+RDLKL N+ LD D H+KI DFG+ + R T CGT
Sbjct: 402 FYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGT 461
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL ++F VD WS G ++Y +L+G+ PF + ++ I+ P +
Sbjct: 462 PDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 521
Query: 137 RKPAASMIVLQLQSNPARRPSVDKLLQ-HEFFSS 169
K + ++ + P +R V ++ H FF +
Sbjct: 522 TKESKDILEKLFEREPTKRLGVTGNIKIHPFFKT 555
>BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta
protein.
Length = 676
Score = 121 bits (292), Expect = 5e-27
Identities = 59/154 (38%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+ G+Q+LHSK II+RDLKL N+ LD D H+KI DFG+ + R T CGT
Sbjct: 452 FYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGT 511
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL ++F VD WS G ++Y +L+G+ PF + ++ I+ P +
Sbjct: 512 PDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 571
Query: 137 RKPAASMIVLQLQSNPARRPSVDKLLQ-HEFFSS 169
K + ++ + P +R V ++ H FF +
Sbjct: 572 TKESKDILEKLFEREPTKRLGVTGNIKIHPFFKT 605
>Z15114-1|CAA78820.1| 536|Homo sapiens protein kinase C gamma
protein.
Length = 536
Score = 121 bits (291), Expect = 6e-27
Identities = 55/144 (38%), Positives = 87/144 (60%)
Query: 12 EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQ 71
EP FY +I +G+ +LH++ II+RDLKL N+ LD + H+KI DFG+ + G +
Sbjct: 293 EPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTR 352
Query: 72 TLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYR 131
T CGTP+YIAPEI+ + + VD WS G ++Y +L G+PPF+ ++ ++ I +
Sbjct: 353 TFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVT 412
Query: 132 IPSSLRKPAASMIVLQLQSNPARR 155
P SL + A ++ L +P +R
Sbjct: 413 YPKSLSREAVAICKGFLTKHPGKR 436
>M60725-1|AAA36411.1| 502|Homo sapiens p70 ribosomal S6 kinase
alpha-II protein.
Length = 502
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I + + +LH K II+RDLK N+ L+ HVK+ DFGL ++G T CGT
Sbjct: 174 FYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGT 233
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I +C+ +P L
Sbjct: 234 IEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYL 293
Query: 137 RKPAASMIVLQLQSNPARR 155
+ A ++ L+ N A R
Sbjct: 294 TQEARDLLKKLLKRNAASR 312
>M60724-1|AAA36410.1| 525|Homo sapiens p70 ribosomal S6 kinase
alpha-I protein.
Length = 525
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I + + +LH K II+RDLK N+ L+ HVK+ DFGL ++G T CGT
Sbjct: 197 FYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGT 256
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I +C+ +P L
Sbjct: 257 IEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYL 316
Query: 137 RKPAASMIVLQLQSNPARR 155
+ A ++ L+ N A R
Sbjct: 317 TQEARDLLKKLLKRNAASR 335
>L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kinase
1 protein.
Length = 735
Score = 121 bits (291), Expect = 6e-27
Identities = 57/164 (34%), Positives = 96/164 (58%), Gaps = 5/164 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ LG+ +LHS II+RDLK N+ LD++ H+K+ DFGL+ ++
Sbjct: 160 TEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKA 219
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GHS D WS G +M+ +L G PF+ K+T I + +
Sbjct: 220 YSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKL 279
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + NPA R +++ +H F+S+
Sbjct: 280 GMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYST 323
Score = 99.5 bits (237), Expect = 2e-20
Identities = 57/170 (33%), Positives = 97/170 (57%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E F +H I V+YLHS+ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 503 RQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAK 562
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF---ETSTL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF + T
Sbjct: 563 QLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTP 622
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +++ + A ++ L +P +R + ++LQH
Sbjct: 623 EEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQH 672
>BC053365-1|AAH53365.1| 451|Homo sapiens RPS6KB1 protein protein.
Length = 451
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I + + +LH K II+RDLK N+ L+ HVK+ DFGL ++G T CGT
Sbjct: 197 FYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLCKESIHDGTVTHTFCGT 256
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I +C+ +P L
Sbjct: 257 IEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKKTIDKILKCKLNLPPYL 316
Query: 137 RKPAASMIVLQLQSNPARR 155
+ A ++ L+ N A R
Sbjct: 317 TQEARDLLKKLLKRNAASR 335
>BC047876-1|AAH47876.1| 697|Homo sapiens protein kinase C, gamma
protein.
Length = 697
Score = 121 bits (291), Expect = 6e-27
Identities = 55/144 (38%), Positives = 87/144 (60%)
Query: 12 EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQ 71
EP FY +I +G+ +LH++ II+RDLKL N+ LD + H+KI DFG+ + G +
Sbjct: 454 EPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTR 513
Query: 72 TLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYR 131
T CGTP+YIAPEI+ + + VD WS G ++Y +L G+PPF+ ++ ++ I +
Sbjct: 514 TFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVT 573
Query: 132 IPSSLRKPAASMIVLQLQSNPARR 155
P SL + A ++ L +P +R
Sbjct: 574 YPKSLSREAVAICKGFLTKHPGKR 597
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 121 bits (291), Expect = 6e-27
Identities = 61/163 (37%), Positives = 95/163 (58%), Gaps = 2/163 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E+R QIL GV Y H ++HRDLK N+ LD ++ KI DFGL+ + +GE
Sbjct: 113 LDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMS-DGEF 171
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+PNY APE+++ + ++ EVDIWS G I+Y LL G PF+ + +K+I
Sbjct: 172 LRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDG 231
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGI 171
+ P L S++ LQ +P +R ++ + +HE+F +
Sbjct: 232 IFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDL 274
>BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 121 bits (291), Expect = 6e-27
Identities = 57/164 (34%), Positives = 96/164 (58%), Gaps = 5/164 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ LG+ +LHS II+RDLK N+ LD++ H+K+ DFGL+ ++
Sbjct: 160 TEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKA 219
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GHS D WS G +M+ +L G PF+ K+T I + +
Sbjct: 220 YSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKL 279
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + NPA R +++ +H F+S+
Sbjct: 280 GMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYST 323
Score = 99.5 bits (237), Expect = 2e-20
Identities = 57/170 (33%), Positives = 97/170 (57%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E F +H I V+YLHS+ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 503 RQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAK 562
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF---ETSTL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF + T
Sbjct: 563 QLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTP 622
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +++ + A ++ L +P +R + ++LQH
Sbjct: 623 EEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQH 672
>BC006106-1|AAH06106.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I L + +LHS+ II+RDLK N+ L H+K+ DFGL +EG T CGT
Sbjct: 173 FYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGT 232
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I + + +P L
Sbjct: 233 IEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYL 292
Query: 137 RKPAASMIVLQLQSNPARR 155
A ++ L+ NP++R
Sbjct: 293 TPDARDLVKKFLKRNPSQR 311
>BC000094-1|AAH00094.3| 482|Homo sapiens ribosomal protein S6
kinase, 70kDa, polypeptide 2 protein.
Length = 482
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I L + +LHS+ II+RDLK N+ L H+K+ DFGL +EG T CGT
Sbjct: 173 FYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGT 232
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I + + +P L
Sbjct: 233 IEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYL 292
Query: 137 RKPAASMIVLQLQSNPARR 155
A ++ L+ NP++R
Sbjct: 293 TPDARDLVKKFLKRNPSQR 311
>AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 735
Score = 121 bits (291), Expect = 6e-27
Identities = 57/164 (34%), Positives = 96/164 (58%), Gaps = 5/164 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ LG+ +LHS II+RDLK N+ LD++ H+K+ DFGL+ ++
Sbjct: 160 TEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKA 219
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GHS D WS G +M+ +L G PF+ K+T I + +
Sbjct: 220 YSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKL 279
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + NPA R +++ +H F+S+
Sbjct: 280 GMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYST 323
Score = 99.5 bits (237), Expect = 2e-20
Identities = 57/170 (33%), Positives = 97/170 (57%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E F +H I V+YLHS+ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 503 RQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAK 562
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF---ETSTL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF + T
Sbjct: 563 QLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTP 622
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +++ + A ++ L +P +R + ++LQH
Sbjct: 623 EEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQH 672
>AL627313-4|CAI14647.1| 578|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 1 protein.
Length = 578
Score = 121 bits (291), Expect = 6e-27
Identities = 57/164 (34%), Positives = 96/164 (58%), Gaps = 5/164 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ LG+ +LHS II+RDLK N+ LD++ H+K+ DFGL+ ++
Sbjct: 3 TEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKA 62
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GHS D WS G +M+ +L G PF+ K+T I + +
Sbjct: 63 YSFCGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKL 122
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
+P L A S++ + NPA R +++ +H F+S+
Sbjct: 123 GMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYST 166
Score = 99.5 bits (237), Expect = 2e-20
Identities = 57/170 (33%), Positives = 97/170 (57%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAA 61
R K +E E F +H I V+YLHS+ ++HRDLK N L++D+ + ++I DFG A
Sbjct: 346 RQKFFSEREASFVLHTIGKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAK 405
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF---ETSTL 118
++ E T C T N++APE+L ++G+ DIWSLG ++YT+L G PF + T
Sbjct: 406 QLRAENGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTP 465
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI ++ + +++ + A ++ L +P +R + ++LQH
Sbjct: 466 EEILTRIGSGKFTLSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQH 515
>AF345987-1|AAK13533.1| 697|Homo sapiens protein kinase C gamma
protein.
Length = 697
Score = 121 bits (291), Expect = 6e-27
Identities = 55/144 (38%), Positives = 87/144 (60%)
Query: 12 EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQ 71
EP FY +I +G+ +LH++ II+RDLKL N+ LD + H+KI DFG+ + G +
Sbjct: 454 EPHAAFYAAEIAIGLFFLHNQGIIYRDLKLDNVMLDAEGHIKITDFGMCKENVFPGTTTR 513
Query: 72 TLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYR 131
T CGTP+YIAPEI+ + + VD WS G ++Y +L G+PPF+ ++ ++ I +
Sbjct: 514 TFCGTPDYIAPEIIAYQPYGKSVDWWSFGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVT 573
Query: 132 IPSSLRKPAASMIVLQLQSNPARR 155
P SL + A ++ L +P +R
Sbjct: 574 YPKSLSREAVAICKGFLTKHPGKR 597
>AF099739-1|AAD20990.1| 482|Homo sapiens S6 kinase-related kinase
protein.
Length = 482
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I L + +LHS+ II+RDLK N+ L H+K+ DFGL +EG T CGT
Sbjct: 173 FYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGT 232
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I + + +P L
Sbjct: 233 IEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYL 292
Query: 137 RKPAASMIVLQLQSNPARR 155
A ++ L+ NP++R
Sbjct: 293 TPDARDLVKKFLKRNPSQR 311
>AF076931-1|AAD46063.1| 482|Homo sapiens serine/threonine kinase 14
beta protein.
Length = 482
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I L + +LHS+ II+RDLK N+ L H+K+ DFGL +EG T CGT
Sbjct: 173 FYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGT 232
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I + + +P L
Sbjct: 233 IEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYL 292
Query: 137 RKPAASMIVLQLQSNPARR 155
A ++ L+ NP++R
Sbjct: 293 TPDARDLVKKFLKRNPSQR 311
>AB019245-1|BAA37145.1| 481|Homo sapiens S6 kinase b protein.
Length = 481
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I L + +LHS+ II+RDLK N+ L H+K+ DFGL +EG T CGT
Sbjct: 172 FYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGT 231
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I + + +P L
Sbjct: 232 IEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYL 291
Query: 137 RKPAASMIVLQLQSNPARR 155
A ++ L+ NP++R
Sbjct: 292 TPDARDLVKKFLKRNPSQR 310
>AB016869-1|BAA34402.1| 495|Homo sapiens p70 ribosomal S6 kinase
beta protein.
Length = 495
Score = 121 bits (291), Expect = 6e-27
Identities = 58/139 (41%), Positives = 82/139 (58%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY+ +I L + +LHS+ II+RDLK N+ L H+K+ DFGL +EG T CGT
Sbjct: 186 FYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGT 245
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
Y+APEIL + GH+ VD WSLG +MY +L G PPF K T +I + + +P L
Sbjct: 246 IEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYL 305
Query: 137 RKPAASMIVLQLQSNPARR 155
A ++ L+ NP++R
Sbjct: 306 TPDARDLVKKFLKRNPSQR 324
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 476 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 534
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 535 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 594
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 595 PKKIAKNAANLIKKLCRDNPSER 617
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 461 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 519
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 520 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 579
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 580 PKKIAKNAANLIKKLCRDNPSER 602
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 476 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 534
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 535 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 594
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 595 PKKIAKNAANLIKKLCRDNPSER 617
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 461 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 519
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 520 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 579
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 580 PKKIAKNAANLIKKLCRDNPSER 602
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 476 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 534
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 535 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 594
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 595 PKKIAKNAANLIKKLCRDNPSER 617
>BC020479-1|AAH20479.1| 466|Homo sapiens AKT3 protein protein.
Length = 466
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AY005799-1|AAF91073.1| 465|Homo sapiens protein kinase B gamma 1
protein.
Length = 465
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 283
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 73 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 131
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 132 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 191
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 192 PKKIAKNAANLIKKLCRDNPSER 214
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 476 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 534
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 535 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 594
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 595 PKKIAKNAANLIKKLCRDNPSER 617
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 449 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 507
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 508 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 567
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 568 PKKIAKNAANLIKKLCRDNPSER 590
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 476 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 534
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 535 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 594
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 595 PKKIAKNAANLIKKLCRDNPSER 617
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 449 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 507
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 508 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 567
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 568 PKKIAKNAANLIKKLCRDNPSER 590
>AL662889-3|CAH73073.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AL662889-2|CAH73072.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AL592151-2|CAH72892.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AL592151-1|CAH72891.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AL591721-2|CAH71867.1| 479|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 479
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AL591721-1|CAH71866.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 476 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 534
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 535 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 594
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 595 PKKIAKNAANLIKKLCRDNPSER 617
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 449 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 507
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 508 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 567
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 568 PKKIAKNAANLIKKLCRDNPSER 590
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 476 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 534
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 535 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 594
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 595 PKKIAKNAANLIKKLCRDNPSER 617
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 120 bits (290), Expect = 8e-27
Identities = 63/143 (44%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 15 TRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLC 74
TRFY ++ YLHSK II+RDLK NL LD + K+ DFG A +I + G++ T C
Sbjct: 449 TRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGF-GKKTWTFC 507
Query: 75 GTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ--CEYRI 132
GTP Y+APEI+ KGH D WSLG +MY LL G PPF TY I +
Sbjct: 508 GTPEYVAPEIILNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEF 567
Query: 133 PSSLRKPAASMIVLQLQSNPARR 155
P + K AA++I + NP+ R
Sbjct: 568 PKKIAKNAANLIKKLCRDNPSER 590
>AJ245709-1|CAB53537.1| 479|Homo sapiens Akt-3 protein protein.
Length = 479
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AF135794-1|AAD24196.1| 479|Homo sapiens AKT3 protein kinase
protein.
Length = 479
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AF124141-1|AAD29089.1| 479|Homo sapiens protein kinase B gamma
protein.
Length = 479
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AF085234-1|AAL40392.1| 479|Homo sapiens STK-2 protein.
Length = 479
Score = 120 bits (290), Expect = 8e-27
Identities = 61/168 (36%), Positives = 93/168 (55%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL LD D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13
protein.
Length = 676
Score = 120 bits (289), Expect = 1e-26
Identities = 58/154 (37%), Positives = 89/154 (57%), Gaps = 1/154 (0%)
Query: 17 FYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCGT 76
FY +I+ G+Q+LHSK II+RDLKL N+ LD D H+KI DFG+ + R T CGT
Sbjct: 452 FYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGT 511
Query: 77 PNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSSL 136
P+YIAPEIL ++F VD WS G ++Y +L+G+ PF + ++ I+ P +
Sbjct: 512 PDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWI 571
Query: 137 RKPAASMIVLQLQSNPARRPSVDKLLQ-HEFFSS 169
K + ++ + P +R + ++ H FF +
Sbjct: 572 TKESKDILEKLFEREPTKRLGMTGNIKIHPFFKT 605
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 120 bits (288), Expect = 1e-26
Identities = 61/164 (37%), Positives = 97/164 (59%), Gaps = 3/164 (1%)
Query: 8 KAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEG 67
+ ++E ETR + QI+ V Y H ++HRDLKL N+ LDD+ ++KI DFGL + + +
Sbjct: 185 RRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGL-SNLYQKD 243
Query: 68 ERKQTLCGTPNYIAPEILTKKGH-SFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIK 126
+ QT CG+P Y +PEI+ + + EVD W+LG ++YTL+ G PF+ K+ ++I
Sbjct: 244 KFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQIS 303
Query: 127 QCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
EYR P+ A +I L NP RR +++ + H + + G
Sbjct: 304 SGEYREPTQ-PSDARGLIRWMLMVNPDRRATIEDIANHWWVNWG 346
>L33881-1|AAB17011.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 119 bits (287), Expect = 2e-26
Identities = 61/160 (38%), Positives = 91/160 (56%), Gaps = 9/160 (5%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R + + E RFY +I L + YLH + II+RDLKL N+ LD + H+K+ D+G+
Sbjct: 336 QRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGL 395
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDT--- 121
G+ T CGTPNYIAPEIL + + F VD W+LG +M+ ++ G+ PF+ D
Sbjct: 396 RPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQ 455
Query: 122 ------YKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
++ I + + RIP SL AAS++ L +P R
Sbjct: 456 NTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKER 495
>L18964-1|AAA60171.1| 587|Homo sapiens protein kinase C iota
protein.
Length = 587
Score = 119 bits (287), Expect = 2e-26
Identities = 61/160 (38%), Positives = 91/160 (56%), Gaps = 9/160 (5%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R + + E RFY +I L + YLH + II+RDLKL N+ LD + H+K+ D+G+
Sbjct: 336 QRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGL 395
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDT--- 121
G+ T CGTPNYIAPEIL + + F VD W+LG +M+ ++ G+ PF+ D
Sbjct: 396 RPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQ 455
Query: 122 ------YKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
++ I + + RIP SL AAS++ L +P R
Sbjct: 456 NTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKER 495
>Z98049-1|CAI20579.1| 733|Homo sapiens ribosomal protein S6 kinase,
90kDa, polypeptide 2 protein.
Length = 733
Score = 118 bits (285), Expect = 3e-26
Identities = 57/162 (35%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+KI DFGL+ +R
Sbjct: 157 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRA 216
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 217 YSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKL 276
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFF 167
+P L A S++ + NP R V+++ +H FF
Sbjct: 277 GMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 318
Score = 86.2 bits (204), Expect = 2e-16
Identities = 51/170 (30%), Positives = 87/170 (51%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAA 61
R + +E E + I + YLHS+ ++HRDLK N+ D+ +++ DFG A
Sbjct: 500 RQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAK 559
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 560 QLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTP 619
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI +Y + S+ A ++ L +P +R + ++L+H
Sbjct: 620 EEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKH 669
>X85106-1|CAA59427.1| 733|Homo sapiens ribosomal S6 kinase protein.
Length = 733
Score = 118 bits (285), Expect = 3e-26
Identities = 57/162 (35%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+KI DFGL+ +R
Sbjct: 157 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRA 216
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 217 YSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKL 276
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFF 167
+P L A S++ + NP R V+++ +H FF
Sbjct: 277 GMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 318
Score = 86.2 bits (204), Expect = 2e-16
Identities = 51/170 (30%), Positives = 87/170 (51%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAA 61
R + +E E + I + YLHS+ ++HRDLK N+ D+ +++ DFG A
Sbjct: 500 RQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAK 559
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 560 QLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTP 619
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI +Y + S+ A ++ L +P +R + ++L+H
Sbjct: 620 EEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKH 669
>X07109-1|CAA30130.1| 673|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta II. ).
Length = 673
Score = 118 bits (285), Expect = 3e-26
Identities = 58/168 (34%), Positives = 96/168 (57%), Gaps = 5/168 (2%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP FY +I +G+ +L SK II+RDLKL N+ LD + H+KI DFG+
Sbjct: 433 QQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI 492
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
++G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+ PFE + ++
Sbjct: 493 WDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQS 552
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR----PSVDK-LLQHEFF 167
I + P S+ K A ++ + +P +R P ++ + +H FF
Sbjct: 553 IMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF 600
>X06318-1|CAA29634.1| 671|Homo sapiens protein ( Human mRNA for
protein kinase C (PKC) type beta I. ).
Length = 671
Score = 118 bits (285), Expect = 3e-26
Identities = 58/168 (34%), Positives = 96/168 (57%), Gaps = 5/168 (2%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP FY +I +G+ +L SK II+RDLKL N+ LD + H+KI DFG+
Sbjct: 433 QQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI 492
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
++G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+ PFE + ++
Sbjct: 493 WDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQS 552
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR----PSVDK-LLQHEFF 167
I + P S+ K A ++ + +P +R P ++ + +H FF
Sbjct: 553 IMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF 600
>M13975-1|AAA60095.1| 673|Homo sapiens protein kinase C beta-II
type protein.
Length = 673
Score = 118 bits (285), Expect = 3e-26
Identities = 58/168 (34%), Positives = 96/168 (57%), Gaps = 5/168 (2%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP FY +I +G+ +L SK II+RDLKL N+ LD + H+KI DFG+
Sbjct: 433 QQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI 492
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
++G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+ PFE + ++
Sbjct: 493 WDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQS 552
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR----PSVDK-LLQHEFF 167
I + P S+ K A ++ + +P +R P ++ + +H FF
Sbjct: 553 IMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF 600
>L07598-1|AAC82496.1| 540|Homo sapiens ribosomal protein S6 kinase
2 protein.
Length = 540
Score = 118 bits (285), Expect = 3e-26
Identities = 57/162 (35%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+KI DFGL+ +R
Sbjct: 158 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRA 217
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 218 YSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGALPFQGKDRKETMSLILKAKL 277
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFF 167
+P L A S++ + NP R V+++ +H FF
Sbjct: 278 GMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 319
>BC036472-1|AAH36472.1| 673|Homo sapiens protein kinase C, beta 1
protein.
Length = 673
Score = 118 bits (285), Expect = 3e-26
Identities = 58/168 (34%), Positives = 96/168 (57%), Gaps = 5/168 (2%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP FY +I +G+ +L SK II+RDLKL N+ LD + H+KI DFG+
Sbjct: 433 QQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI 492
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
++G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+ PFE + ++
Sbjct: 493 WDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQS 552
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR----PSVDK-LLQHEFF 167
I + P S+ K A ++ + +P +R P ++ + +H FF
Sbjct: 553 IMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF 600
>BC022016-1|AAH22016.3| 587|Homo sapiens protein kinase C, iota
protein.
Length = 587
Score = 118 bits (285), Expect = 3e-26
Identities = 60/160 (37%), Positives = 91/160 (56%), Gaps = 9/160 (5%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R + + E RFY +I L + YLH + II+RDLKL N+ LD + H+K+ D+G+
Sbjct: 336 QRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGL 395
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDT--- 121
G+ T CGTPNYIAPEIL + + F VD W+LG +M+ ++ G+ PF+ D
Sbjct: 396 RPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQ 455
Query: 122 ------YKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
++ I + + RIP S+ AAS++ L +P R
Sbjct: 456 NTEDYLFQVILEKQIRIPRSMSVKAASVLKSFLNKDPKER 495
>BC002363-1|AAH02363.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 118 bits (285), Expect = 3e-26
Identities = 57/162 (35%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+KI DFGL+ +R
Sbjct: 157 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRA 216
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 217 YSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKL 276
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFF 167
+P L A S++ + NP R V+++ +H FF
Sbjct: 277 GMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 318
Score = 86.2 bits (204), Expect = 2e-16
Identities = 51/170 (30%), Positives = 87/170 (51%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAA 61
R + +E E + I + YLHS+ ++HRDLK N+ D+ +++ DFG A
Sbjct: 500 RQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAK 559
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 560 QLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTP 619
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI +Y + S+ A ++ L +P +R + ++L+H
Sbjct: 620 EEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKH 669
>AL022069-2|CAI19651.1| 733|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 733
Score = 118 bits (285), Expect = 3e-26
Identities = 57/162 (35%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+KI DFGL+ +R
Sbjct: 157 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRA 216
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 217 YSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKL 276
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFF 167
+P L A S++ + NP R V+++ +H FF
Sbjct: 277 GMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 318
Score = 86.2 bits (204), Expect = 2e-16
Identities = 51/170 (30%), Positives = 87/170 (51%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAA 61
R + +E E + I + YLHS+ ++HRDLK N+ D+ +++ DFG A
Sbjct: 500 RQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAK 559
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 560 QLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTP 619
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI +Y + S+ A ++ L +P +R + ++L+H
Sbjct: 620 EEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKH 669
>AC002299-2|AAB97934.1| 496|Homo sapiens Protein kinase C beta (5'
partial) splice form_ protein.
Length = 496
Score = 118 bits (285), Expect = 3e-26
Identities = 58/168 (34%), Positives = 96/168 (57%), Gaps = 5/168 (2%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP FY +I +G+ +L SK II+RDLKL N+ LD + H+KI DFG+
Sbjct: 256 QQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI 315
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
++G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+ PFE + ++
Sbjct: 316 WDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQS 375
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR----PSVDK-LLQHEFF 167
I + P S+ K A ++ + +P +R P ++ + +H FF
Sbjct: 376 IMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF 423
>AC002299-1|AAB97933.1| 494|Homo sapiens Protein kinase C beta (5'
partial) splice form_1 protein.
Length = 494
Score = 118 bits (285), Expect = 3e-26
Identities = 58/168 (34%), Positives = 96/168 (57%), Gaps = 5/168 (2%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ EP FY +I +G+ +L SK II+RDLKL N+ LD + H+KI DFG+
Sbjct: 256 QQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENI 315
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
++G +T CGTP+YIAPEI+ + + VD W+ G ++Y +L G+ PFE + ++
Sbjct: 316 WDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQS 375
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR----PSVDK-LLQHEFF 167
I + P S+ K A ++ + +P +R P ++ + +H FF
Sbjct: 376 IMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF 423
>AB209116-1|BAD92353.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 isoform b variant protein.
Length = 806
Score = 118 bits (285), Expect = 3e-26
Identities = 57/162 (35%), Positives = 93/162 (57%), Gaps = 5/162 (3%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+KI DFGL+ +R
Sbjct: 230 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRA 289
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 290 YSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKL 349
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFF 167
+P L A S++ + NP R V+++ +H FF
Sbjct: 350 GMPQFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFF 391
Score = 86.2 bits (204), Expect = 2e-16
Identities = 51/170 (30%), Positives = 87/170 (51%), Gaps = 11/170 (6%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDL----HVKIGDFGLAA 61
R + +E E + I + YLHS+ ++HRDLK N+ D+ +++ DFG A
Sbjct: 573 RQRYFSEREASDVLCTITKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAK 632
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFET---STL 118
++ T C T N++APE+L ++G+ DIWSLG ++YT+L G PF T
Sbjct: 633 QLRAGNGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTP 692
Query: 119 KDTYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
++ RI +Y + S+ A ++ L +P +R + ++L+H
Sbjct: 693 EEILARIGSGKYALSGGNWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKH 742
>BC121154-1|AAI21155.1| 465|Homo sapiens v-akt murine thymoma viral
oncogene homolog 3 (protein kinase B, gamma) protein.
Length = 465
Score = 118 bits (284), Expect = 4e-26
Identities = 60/168 (35%), Positives = 92/168 (54%), Gaps = 5/168 (2%)
Query: 6 RIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEY 65
R + +E TRFY +I+ + YLHS +I++RDLKL NL D D H+KI DFGL
Sbjct: 239 RERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMRDKDGHIKITDFGLCKEGIT 298
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRI 125
+ +T CGTP Y+APE+L + VD W LG +MY ++ G+ PF + ++ I
Sbjct: 299 DAATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELI 358
Query: 126 KQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFS 168
+ + P +L A S++ L +P +R ++++H FFS
Sbjct: 359 LMEDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFS 406
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 118 bits (284), Expect = 4e-26
Identities = 65/191 (34%), Positives = 107/191 (56%), Gaps = 8/191 (4%)
Query: 8 KAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLA--ARIEY 65
K + E E R Y+ Q++ V++LH ++HRDLK+ NL LD+D ++K+ DFGL+ A I
Sbjct: 156 KRLEESEARRYIRQLISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILG 215
Query: 66 EGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF--ETSTLKDTYK 123
+ T CG+P Y APE+L +K + ++D+WS+G MY +L G PF E +L+ Y+
Sbjct: 216 YSDPFSTQCGSPAYAAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEPFSLRALYQ 275
Query: 124 RIKQCEYR-IPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGLPVSCLT 182
++ E +P+ L A S + L+ +P +RP++ + L + + + V C
Sbjct: 276 KMVDKEMNPLPTQLSTGAISFLRSLLEPDPVKRPNIQQALANRWLNENYTG---KVPCNV 332
Query: 183 TAPRTDQLEGM 193
T P LE +
Sbjct: 333 TYPNRISLEDL 343
>X07767-1|CAA30597.1| 351|Homo sapiens protein ( Human mRNA for
cAMP-dependent protein kinase catalytic subunit type
alpha (EC 2.7.1.37). ).
Length = 351
Score = 118 bits (283), Expect = 6e-26
Identities = 62/170 (36%), Positives = 96/170 (56%), Gaps = 8/170 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
I + R PS ++ LQ + +R V+ + H++F++
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300
>DQ667173-1|ABG25918.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 118 bits (283), Expect = 6e-26
Identities = 62/170 (36%), Positives = 96/170 (56%), Gaps = 8/170 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
I + R PS ++ LQ + +R V+ + H++F++
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300
>BC108259-1|AAI08260.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 118 bits (283), Expect = 6e-26
Identities = 62/170 (36%), Positives = 96/170 (56%), Gaps = 8/170 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
I + R PS ++ LQ + +R V+ + H++F++
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300
>BC039846-1|AAH39846.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, alpha protein.
Length = 351
Score = 118 bits (283), Expect = 6e-26
Identities = 62/170 (36%), Positives = 96/170 (56%), Gaps = 8/170 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR-----PSVDKLLQHEFFSS 169
I + R PS ++ LQ + +R V+ + H++F++
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 117 bits (282), Expect = 8e-26
Identities = 54/162 (33%), Positives = 95/162 (58%), Gaps = 3/162 (1%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LH I++RDLK N+ LD+ H+K+ DFGL+ + ++
Sbjct: 171 TEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKA 230
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GHS D WS G +M+ +L G PF+ +T I + +
Sbjct: 231 YSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKL 290
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR---PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FF++
Sbjct: 291 GMPQLLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFAN 332
Score = 89.4 bits (212), Expect = 2e-17
Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 11/172 (6%)
Query: 8 KAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARI 63
K +E E ++ I V YLH + ++HRDLK N L++D+ ++I DFG A ++
Sbjct: 513 KCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQL 572
Query: 64 EYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF---ETSTLKD 120
E T C T N++APE+L ++G+ DIWSLG + YT+L G PF T ++
Sbjct: 573 RGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEE 632
Query: 121 TYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFS 168
RI ++ + ++ A ++ L +P +R + +++L+H + +
Sbjct: 633 ILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWIT 684
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 117 bits (282), Expect = 8e-26
Identities = 54/162 (33%), Positives = 95/162 (58%), Gaps = 3/162 (1%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LH I++RDLK N+ LD+ H+K+ DFGL+ + ++
Sbjct: 171 TEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKA 230
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GHS D WS G +M+ +L G PF+ +T I + +
Sbjct: 231 YSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKL 290
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR---PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FF++
Sbjct: 291 GMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFAN 332
Score = 89.4 bits (212), Expect = 2e-17
Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 11/172 (6%)
Query: 8 KAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARI 63
K +E E ++ I V YLH + ++HRDLK N L++D+ ++I DFG A ++
Sbjct: 513 KCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQL 572
Query: 64 EYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF---ETSTLKD 120
E T C T N++APE+L ++G+ DIWSLG + YT+L G PF T ++
Sbjct: 573 RGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEE 632
Query: 121 TYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFS 168
RI ++ + ++ A ++ L +P +R + +++L+H + +
Sbjct: 633 ILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWIT 684
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 117 bits (282), Expect = 8e-26
Identities = 54/162 (33%), Positives = 95/162 (58%), Gaps = 3/162 (1%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LH I++RDLK N+ LD+ H+K+ DFGL+ + ++
Sbjct: 171 TEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKA 230
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GHS D WS G +M+ +L G PF+ +T I + +
Sbjct: 231 YSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKL 290
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR---PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FF++
Sbjct: 291 GMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFAN 332
Score = 89.4 bits (212), Expect = 2e-17
Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 11/172 (6%)
Query: 8 KAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARI 63
K +E E ++ I V YLH + ++HRDLK N L++D+ ++I DFG A ++
Sbjct: 513 KCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQL 572
Query: 64 EYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF---ETSTLKD 120
E T C T N++APE+L ++G+ DIWSLG + YT+L G PF T ++
Sbjct: 573 RGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEE 632
Query: 121 TYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFS 168
RI ++ + ++ A ++ L +P +R + +++L+H + +
Sbjct: 633 ILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWIT 684
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 117 bits (282), Expect = 8e-26
Identities = 54/162 (33%), Positives = 95/162 (58%), Gaps = 3/162 (1%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LH I++RDLK N+ LD+ H+K+ DFGL+ + ++
Sbjct: 171 TEEDVKFYLAELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKA 230
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GHS D WS G +M+ +L G PF+ +T I + +
Sbjct: 231 YSFCGTVEYMAPEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKL 290
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR---PSVDKLLQHEFFSS 169
+P L A S++ + + NPA R V+++ +H FF++
Sbjct: 291 GMPQFLSAEAQSLLRMLFKRNPANRLGSEGVEEIKRHLFFAN 332
Score = 89.4 bits (212), Expect = 2e-17
Identities = 52/172 (30%), Positives = 91/172 (52%), Gaps = 11/172 (6%)
Query: 8 KAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGN-LFLDDDLH---VKIGDFGLAARI 63
K +E E ++ I V YLH + ++HRDLK N L++D+ ++I DFG A ++
Sbjct: 513 KCFSEREASDILYVISKTVDYLHCQGVVHRDLKPSNILYMDESASADSIRICDFGFAKQL 572
Query: 64 EYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPF---ETSTLKD 120
E T C T N++APE+L ++G+ DIWSLG + YT+L G PF T ++
Sbjct: 573 RGENGLLLTPCYTANFVAPEVLMQQGYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEE 632
Query: 121 TYKRIKQCEYRIP----SSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFS 168
RI ++ + ++ A ++ L +P +R + +++L+H + +
Sbjct: 633 ILLRIGNGKFSLSGGNWDNISDGAKDLLSHMLHMDPHQRYTAEQILKHSWIT 684
>M34181-1|AAA60170.1| 351|Homo sapiens cAMP-dependent protein
kinase catalytic subunit protein.
Length = 351
Score = 117 bits (281), Expect = 1e-25
Identities = 59/151 (39%), Positives = 87/151 (57%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + R PS ++ LQ + +R
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
>DQ667174-1|ABG25919.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 117 bits (281), Expect = 1e-25
Identities = 59/151 (39%), Positives = 87/151 (57%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 181 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 240
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 241 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 297
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + R PS ++ LQ + +R
Sbjct: 298 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 328
>AL450063-12|CAI16855.1| 321|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 321
Score = 117 bits (281), Expect = 1e-25
Identities = 59/151 (39%), Positives = 87/151 (57%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 104 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 163
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 164 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 220
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + R PS ++ LQ + +R
Sbjct: 221 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 251
>AL450063-3|CAI16846.1| 398|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 398
Score = 117 bits (281), Expect = 1e-25
Identities = 59/151 (39%), Positives = 87/151 (57%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 181 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 240
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 241 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 297
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + R PS ++ LQ + +R
Sbjct: 298 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 328
>AL450063-2|CAI16845.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 117 bits (281), Expect = 1e-25
Identities = 59/151 (39%), Positives = 87/151 (57%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + R PS ++ LQ + +R
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
>AL359504-2|CAI14541.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 117 bits (281), Expect = 1e-25
Identities = 59/151 (39%), Positives = 87/151 (57%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + R PS ++ LQ + +R
Sbjct: 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 281
>AB209189-1|BAD92426.1| 365|Homo sapiens cAMP-dependent protein
kinase catalytic subunit beta isoform 2 variant protein.
Length = 365
Score = 117 bits (281), Expect = 1e-25
Identities = 59/151 (39%), Positives = 87/151 (57%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YLHS +I+RDLK NL +D ++++ DFG A R++
Sbjct: 160 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 219
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 220 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 276
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + R PS ++ LQ + +R
Sbjct: 277 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKR 307
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 116 bits (279), Expect = 2e-25
Identities = 62/162 (38%), Positives = 94/162 (58%), Gaps = 3/162 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
++E E R + QI+ V Y H R++HRDLKL N+ LD + ++KI DFGL + + ++G+
Sbjct: 147 LSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGL-SNLYHQGKF 205
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
QT CG+P Y +PEI+ K ++ EVD WSLG ++Y L+ G PF+ K K+I
Sbjct: 206 LQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNG 265
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
YR P A +I L NP RR +++ + H + + G
Sbjct: 266 AYREPPK-PSDACGLIRWLLMVNPTRRATLEDVASHWWVNWG 306
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 116 bits (279), Expect = 2e-25
Identities = 62/162 (38%), Positives = 94/162 (58%), Gaps = 3/162 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
++E E R + QI+ V Y H R++HRDLKL N+ LD + ++KI DFGL + + ++G+
Sbjct: 147 LSEREARHFFRQIVSAVHYCHQNRVVHRDLKLENILLDANGNIKIADFGL-SNLYHQGKF 205
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
QT CG+P Y +PEI+ K ++ EVD WSLG ++Y L+ G PF+ K K+I
Sbjct: 206 LQTFCGSPLYASPEIVNGKPYTGPEVDSWSLGVLLYILVHGTMPFDGHDHKILVKQISNG 265
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
YR P A +I L NP RR +++ + H + + G
Sbjct: 266 AYREPPK-PSDACGLIRWLLMVNPTRRATLEDVASHWWVNWG 306
>Y15056-1|CAA75341.1| 556|Homo sapiens PkB kinase protein.
Length = 556
Score = 116 bits (278), Expect = 2e-25
Identities = 61/173 (35%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++I + E TRFY +I+ ++YLH K IIHRDLK N+ L++D+H++I DFG A +
Sbjct: 172 RKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS 231
Query: 65 YEGE--RKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
E + R + GT Y++PE+LT+K D+W+LGCI+Y L+ G PPF +
Sbjct: 232 PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIF 291
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDK------LLQHEFFSS 169
++I + EY P A ++ L + +R ++ L H FF S
Sbjct: 292 QKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFES 344
>CR536517-1|CAG38755.1| 556|Homo sapiens PDPK1 protein.
Length = 556
Score = 116 bits (278), Expect = 2e-25
Identities = 61/173 (35%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++I + E TRFY +I+ ++YLH K IIHRDLK N+ L++D+H++I DFG A +
Sbjct: 172 RKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS 231
Query: 65 YEGE--RKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
E + R + GT Y++PE+LT+K D+W+LGCI+Y L+ G PPF +
Sbjct: 232 PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIF 291
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDK------LLQHEFFSS 169
++I + EY P A ++ L + +R ++ L H FF S
Sbjct: 292 QKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFES 344
>BT019534-1|AAV38341.1| 344|Homo sapiens serine/threonine kinase 12
protein.
Length = 344
Score = 116 bits (278), Expect = 2e-25
Identities = 59/166 (35%), Positives = 100/166 (60%), Gaps = 5/166 (3%)
Query: 2 ELHKRI-KAIT--EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFG 58
EL+K + K+ T E T M ++ + Y H K++IHRD+K NL L +KI DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 59 LAARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTL 118
+ + R++T+CGT +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++
Sbjct: 221 WS--VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
Query: 119 KDTYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+TY+RI + + + P+S+ A +I L+ NP+ R + ++ H
Sbjct: 279 NETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQVSAH 324
>BC080581-1|AAH80581.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 116 bits (278), Expect = 2e-25
Identities = 59/166 (35%), Positives = 100/166 (60%), Gaps = 5/166 (3%)
Query: 2 ELHKRI-KAIT--EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFG 58
EL+K + K+ T E T M ++ + Y H K++IHRD+K NL L +KI DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 59 LAARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTL 118
+ + R++T+CGT +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++
Sbjct: 221 WS--VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
Query: 119 KDTYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+TY+RI + + + P+S+ A +I L+ NP+ R + ++ H
Sbjct: 279 NETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQVSAH 324
>BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein.
Length = 783
Score = 116 bits (278), Expect = 2e-25
Identities = 59/158 (37%), Positives = 89/158 (56%), Gaps = 2/158 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
++E E R QIL V+Y H I+HRDLK NL LD ++ +K+ DFG GE
Sbjct: 121 LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFG-NFYKSGEP 179
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
T CG+P Y APE+ K + ++DIWSLG ++Y L+ G PF+ L +R+ +
Sbjct: 180 LSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEG 239
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEF 166
+RIP + + S+I L +PARR ++ ++ QH +
Sbjct: 240 RFRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRW 277
>BC035058-1|AAH35058.1| 351|Homo sapiens protein kinase,
cAMP-dependent, catalytic, beta protein.
Length = 351
Score = 116 bits (278), Expect = 2e-25
Identities = 59/151 (39%), Positives = 88/151 (58%), Gaps = 3/151 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+RI +EP RFY QI+L +YL+S II+RDLK NL +D ++++ DFG A R++
Sbjct: 134 RRIGRFSEPHARFYAAQIVLTFEYLNSLDIIYRDLKPENLLIDHQGYIQVTDFGFAKRVK 193
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R TLCGTP Y+APEI+ KG++ VD W+LG ++Y + G PPF Y++
Sbjct: 194 ---GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I + R PS+ ++ LQ + +R
Sbjct: 251 IVSGKVRFPSNFSSDLKDLLRNLLQVDLTKR 281
>BC013300-1|AAH13300.2| 371|Homo sapiens AURKB protein protein.
Length = 371
Score = 116 bits (278), Expect = 2e-25
Identities = 59/166 (35%), Positives = 100/166 (60%), Gaps = 5/166 (3%)
Query: 2 ELHKRI-KAIT--EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFG 58
EL+K + K+ T E T M ++ + Y H K++IHRD+K NL L +KI DFG
Sbjct: 188 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 247
Query: 59 LAARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTL 118
+ + R++T+CGT +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++
Sbjct: 248 WS--VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 305
Query: 119 KDTYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+TY+RI + + + P+S+ A +I L+ NP+ R + ++ H
Sbjct: 306 NETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAH 351
>BC012103-1|AAH12103.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 116 bits (278), Expect = 2e-25
Identities = 61/173 (35%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++I + E TRFY +I+ ++YLH K IIHRDLK N+ L++D+H++I DFG A +
Sbjct: 172 RKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS 231
Query: 65 YEGE--RKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
E + R + GT Y++PE+LT+K D+W+LGCI+Y L+ G PPF +
Sbjct: 232 PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIF 291
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDK------LLQHEFFSS 169
++I + EY P A ++ L + +R ++ L H FF S
Sbjct: 292 QKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFES 344
>BC009751-1|AAH09751.1| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 116 bits (278), Expect = 2e-25
Identities = 59/166 (35%), Positives = 100/166 (60%), Gaps = 5/166 (3%)
Query: 2 ELHKRI-KAIT--EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFG 58
EL+K + K+ T E T M ++ + Y H K++IHRD+K NL L +KI DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 59 LAARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTL 118
+ + R++T+CGT +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++
Sbjct: 221 WS--VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
Query: 119 KDTYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+TY+RI + + + P+S+ A +I L+ NP+ R + ++ H
Sbjct: 279 NETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAH 324
>BC000442-1|AAH00442.3| 344|Homo sapiens aurora kinase B protein.
Length = 344
Score = 116 bits (278), Expect = 2e-25
Identities = 59/166 (35%), Positives = 100/166 (60%), Gaps = 5/166 (3%)
Query: 2 ELHKRI-KAIT--EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFG 58
EL+K + K+ T E T M ++ + Y H K++IHRD+K NL L +KI DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 59 LAARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTL 118
+ + R++T+CGT +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++
Sbjct: 221 WS--VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
Query: 119 KDTYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+TY+RI + + + P+S+ A +I L+ NP+ R + ++ H
Sbjct: 279 NETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQVSAH 324
>AL022069-1|CAI19650.1| 166|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 2 protein.
Length = 166
Score = 116 bits (278), Expect = 2e-25
Identities = 53/145 (36%), Positives = 85/145 (58%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERK 70
TE + +FY+ ++ L + +LHS II+RDLK N+ LD++ H+KI DFGL+ +R
Sbjct: 3 TEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRA 62
Query: 71 QTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEY 130
+ CGT Y+APE++ ++GH+ D WS G +M+ +L G PF+ K+T I + +
Sbjct: 63 YSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKL 122
Query: 131 RIPSSLRKPAASMIVLQLQSNPARR 155
+P L A S++ + NP R
Sbjct: 123 GMPQFLSGEAQSLLRALFKRNPCNR 147
>AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein.
Length = 764
Score = 116 bits (278), Expect = 2e-25
Identities = 59/158 (37%), Positives = 89/158 (56%), Gaps = 2/158 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
++E E R QIL V+Y H I+HRDLK NL LD ++ +K+ DFG GE
Sbjct: 102 LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFG-NFYKSGEP 160
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
T CG+P Y APE+ K + ++DIWSLG ++Y L+ G PF+ L +R+ +
Sbjct: 161 LSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEG 220
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEF 166
+RIP + + S+I L +PARR ++ ++ QH +
Sbjct: 221 RFRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRW 258
>AF017995-1|AAC51825.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 protein.
Length = 556
Score = 116 bits (278), Expect = 2e-25
Identities = 61/173 (35%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++I + E TRFY +I+ ++YLH K IIHRDLK N+ L++D+H++I DFG A +
Sbjct: 172 RKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS 231
Query: 65 YEGE--RKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
E + R + GT Y++PE+LT+K D+W+LGCI+Y L+ G PPF +
Sbjct: 232 PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIF 291
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDK------LLQHEFFSS 169
++I + EY P A ++ L + +R ++ L H FF S
Sbjct: 292 QKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFES 344
>AF008552-1|AAC12709.1| 344|Homo sapiens aurora-related kinase 2
protein.
Length = 344
Score = 116 bits (278), Expect = 2e-25
Identities = 59/166 (35%), Positives = 100/166 (60%), Gaps = 5/166 (3%)
Query: 2 ELHKRI-KAIT--EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFG 58
EL+K + K+ T E T M ++ + Y H K++IHRD+K NL L +KI DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 59 LAARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTL 118
+ + R++T+CGT +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++
Sbjct: 221 WS--VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
Query: 119 KDTYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+TY+RI + + + P+S+ A +I L+ NP+ R + ++ H
Sbjct: 279 NETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQVSAH 324
>AC005591-1|AAC33797.1| 367|Homo sapiens PkB-like protein.
Length = 367
Score = 116 bits (278), Expect = 2e-25
Identities = 61/173 (35%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++I + E TRFY +I+ ++YLH K IIHRDLK N+ L++D+H++I DFG A +
Sbjct: 164 RKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS 223
Query: 65 YEGE--RKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
E + R + GT Y++PE+LT+K D+W+LGCI+Y L+ G PPF +
Sbjct: 224 PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIF 283
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDK------LLQHEFFSS 169
++I + EY P A ++ L + +R ++ L H FF S
Sbjct: 284 QKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFES 336
>AB209835-1|BAD93072.1| 492|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 492
Score = 116 bits (278), Expect = 2e-25
Identities = 61/173 (35%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++I + E TRFY +I+ ++YLH K IIHRDLK N+ L++D+H++I DFG A +
Sbjct: 210 RKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS 269
Query: 65 YEGE--RKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
E + R + GT Y++PE+LT+K D+W+LGCI+Y L+ G PPF +
Sbjct: 270 PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIF 329
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDK------LLQHEFFSS 169
++I + EY P A ++ L + +R ++ L H FF S
Sbjct: 330 QKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFES 382
>AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protein
kinase protein.
Length = 783
Score = 116 bits (278), Expect = 2e-25
Identities = 59/158 (37%), Positives = 89/158 (56%), Gaps = 2/158 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
++E E R QIL V+Y H I+HRDLK NL LD ++ +K+ DFG GE
Sbjct: 121 LSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFG-NFYKSGEP 179
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
T CG+P Y APE+ K + ++DIWSLG ++Y L+ G PF+ L +R+ +
Sbjct: 180 LSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEG 239
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEF 166
+RIP + + S+I L +PARR ++ ++ QH +
Sbjct: 240 RFRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRW 277
>AB011450-1|BAA32136.1| 344|Homo sapiens aurora and IPL1-like
midbody-associated protein kinase-1 protein.
Length = 344
Score = 116 bits (278), Expect = 2e-25
Identities = 59/166 (35%), Positives = 100/166 (60%), Gaps = 5/166 (3%)
Query: 2 ELHKRI-KAIT--EPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFG 58
EL+K + K+ T E T M ++ + Y H K++IHRD+K NL L +KI DFG
Sbjct: 161 ELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 220
Query: 59 LAARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTL 118
+ + R++T+CGT +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++
Sbjct: 221 WS--VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 278
Query: 119 KDTYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+TY+RI + + + P+S+ A +I L+ NP+ R + ++ H
Sbjct: 279 NETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQVSAH 324
>BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein.
Length = 1102
Score = 115 bits (276), Expect = 4e-25
Identities = 59/162 (36%), Positives = 95/162 (58%), Gaps = 2/162 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QI+ V + H + I+HRDLK NL LD +L++KI DFG + + G+
Sbjct: 1 MAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFS-NLFTPGQL 59
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+P Y APE+ K + +VDIWSLG ++Y L+ G PF+ STL++ R+
Sbjct: 60 LKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSG 119
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
++RIP + +I L +P +R S++++ +H++ G
Sbjct: 120 KFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLG 161
>BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein.
Length = 1203
Score = 115 bits (276), Expect = 4e-25
Identities = 59/162 (36%), Positives = 95/162 (58%), Gaps = 2/162 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QI+ V + H + I+HRDLK NL LD +L++KI DFG + + G+
Sbjct: 102 MAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFS-NLFTPGQL 160
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+P Y APE+ K + +VDIWSLG ++Y L+ G PF+ STL++ R+
Sbjct: 161 LKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSG 220
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
++RIP + +I L +P +R S++++ +H++ G
Sbjct: 221 KFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLG 262
>BC036422-1|AAH36422.1| 436|Homo sapiens hypothetical protein
MGC42105 protein.
Length = 436
Score = 115 bits (276), Expect = 4e-25
Identities = 57/168 (33%), Positives = 91/168 (54%), Gaps = 2/168 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
++EPE++ QI+ V+++H +IIHRDLK N+F + VK+GDFG + + +GE
Sbjct: 168 LSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFST-VSKKGEM 226
Query: 70 KQTLCGTPNYIAPEILTKKGH-SFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
T CG+P Y APE+ + + VDIW+LG ++Y ++ G PF T+ K I +
Sbjct: 227 LNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEG 286
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGL 176
Y +P + +P +I LQ P R +D ++ E+ P L
Sbjct: 287 TYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPL 334
>AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein.
Length = 1371
Score = 115 bits (276), Expect = 4e-25
Identities = 59/162 (36%), Positives = 95/162 (58%), Gaps = 2/162 (1%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QI+ V + H + I+HRDLK NL LD +L++KI DFG + + G+
Sbjct: 210 MAEKEARRKFKQIVTAVYFCHCRNIVHRDLKAENLLLDANLNIKIADFGFS-NLFTPGQL 268
Query: 70 KQTLCGTPNYIAPEILTKKGHSF-EVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQC 128
+T CG+P Y APE+ K + +VDIWSLG ++Y L+ G PF+ STL++ R+
Sbjct: 269 LKTWCGSPPYAAPELFEGKEYDGPKVDIWSLGVVLYVLVCGALPFDGSTLQNLRARVLSG 328
Query: 129 EYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSG 170
++RIP + +I L +P +R S++++ +H++ G
Sbjct: 329 KFRIPFFMSTECEHLIRHMLVLDPNKRLSMEQICKHKWMKLG 370
>AK222581-1|BAD96301.1| 556|Homo sapiens 3-phosphoinositide
dependent protein kinase-1 variant protein.
Length = 556
Score = 114 bits (275), Expect = 5e-25
Identities = 61/173 (35%), Positives = 94/173 (54%), Gaps = 8/173 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++I + E TRFY +I+ +YLH K IIHRDLK N+ L++D+H++I DFG A +
Sbjct: 172 RKIGSFDETCTRFYTAEIVSASEYLHGKGIIHRDLKPENILLNEDMHIQITDFGTAKVLS 231
Query: 65 YEGE--RKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
E + R + GT Y++PE+LT+K D+W+LGCI+Y L+ G PPF +
Sbjct: 232 PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIF 291
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDK------LLQHEFFSS 169
++I + EY P A ++ L + +R ++ L H FF S
Sbjct: 292 QKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFES 344
>AL121914-4|CAM45838.1| 347|Homo sapiens aurora kinase A protein.
Length = 347
Score = 113 bits (273), Expect = 9e-25
Identities = 52/123 (42%), Positives = 77/123 (62%), Gaps = 2/123 (1%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+++ E T Y+ ++ + Y HSKR+IHRD+K NL L +KI DFG + +
Sbjct: 223 QKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VH 280
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
R+ TLCGT +Y+ PE++ + H +VD+WSLG + Y LVGKPPFE +T ++TYKR
Sbjct: 281 APSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKR 340
Query: 125 IKQ 127
I +
Sbjct: 341 ISR 343
>BC034044-1|AAH34044.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 113 bits (272), Expect = 1e-24
Identities = 75/230 (32%), Positives = 113/230 (49%), Gaps = 12/230 (5%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLH---VKIGDFGLAARIEYEG 67
+E + +HQIL V ++H I+HRDLK NL L VK+ DFGLA ++ E
Sbjct: 109 SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQ 168
Query: 68 ERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ 127
+ GTP Y++PE+L K + VDIW+ G I+Y LLVG PPF Y++IK
Sbjct: 169 QAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKA 228
Query: 128 CEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGL-----PV 178
Y PS ++ A ++I L NPA+R + D+ L+H + A + V
Sbjct: 229 GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
Query: 179 SCLTTAPRTDQLEGMLVHRRPLNEVHANEQETMAVDSPVKREATPAGPRA 228
CL +L+G ++ ++ + +++ A SP A AG A
Sbjct: 289 ECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAA 338
>AL713896-5|CAI13788.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 113 bits (272), Expect = 1e-24
Identities = 75/230 (32%), Positives = 113/230 (49%), Gaps = 12/230 (5%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLH---VKIGDFGLAARIEYEG 67
+E + +HQIL V ++H I+HRDLK NL L VK+ DFGLA ++ E
Sbjct: 109 SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQ 168
Query: 68 ERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ 127
+ GTP Y++PE+L K + VDIW+ G I+Y LLVG PPF Y++IK
Sbjct: 169 QAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKA 228
Query: 128 CEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGL-----PV 178
Y PS ++ A ++I L NPA+R + D+ L+H + A + V
Sbjct: 229 GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
Query: 179 SCLTTAPRTDQLEGMLVHRRPLNEVHANEQETMAVDSPVKREATPAGPRA 228
CL +L+G ++ ++ + +++ A SP A AG A
Sbjct: 289 ECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAA 338
>AL713896-2|CAI13791.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 113 bits (272), Expect = 1e-24
Identities = 75/230 (32%), Positives = 113/230 (49%), Gaps = 12/230 (5%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLH---VKIGDFGLAARIEYEG 67
+E + +HQIL V ++H I+HRDLK NL L VK+ DFGLA ++ E
Sbjct: 109 SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQ 168
Query: 68 ERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ 127
+ GTP Y++PE+L K + VDIW+ G I+Y LLVG PPF Y++IK
Sbjct: 169 QAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKA 228
Query: 128 CEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGL-----PV 178
Y PS ++ A ++I L NPA+R + D+ L+H + A + V
Sbjct: 229 GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
Query: 179 SCLTTAPRTDQLEGMLVHRRPLNEVHANEQETMAVDSPVKREATPAGPRA 228
CL +L+G ++ ++ + +++ A SP A AG A
Sbjct: 289 ECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAA 338
>AL596247-5|CAI13967.1| 516|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 516
Score = 113 bits (272), Expect = 1e-24
Identities = 75/230 (32%), Positives = 113/230 (49%), Gaps = 12/230 (5%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLH---VKIGDFGLAARIEYEG 67
+E + +HQIL V ++H I+HRDLK NL L VK+ DFGLA ++ E
Sbjct: 109 SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQ 168
Query: 68 ERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ 127
+ GTP Y++PE+L K + VDIW+ G I+Y LLVG PPF Y++IK
Sbjct: 169 QAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKA 228
Query: 128 CEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGL-----PV 178
Y PS ++ A ++I L NPA+R + D+ L+H + A + V
Sbjct: 229 GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
Query: 179 SCLTTAPRTDQLEGMLVHRRPLNEVHANEQETMAVDSPVKREATPAGPRA 228
CL +L+G ++ ++ + +++ A SP A AG A
Sbjct: 289 ECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAA 338
>AL596247-2|CAI13968.1| 527|Homo sapiens
calcium/calmodulin-dependent protein kinase (CaM kinase)
II gamma protein.
Length = 527
Score = 113 bits (272), Expect = 1e-24
Identities = 75/230 (32%), Positives = 113/230 (49%), Gaps = 12/230 (5%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLH---VKIGDFGLAARIEYEG 67
+E + +HQIL V ++H I+HRDLK NL L VK+ DFGLA ++ E
Sbjct: 109 SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQ 168
Query: 68 ERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ 127
+ GTP Y++PE+L K + VDIW+ G I+Y LLVG PPF Y++IK
Sbjct: 169 QAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKA 228
Query: 128 CEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGL-----PV 178
Y PS ++ A ++I L NPA+R + D+ L+H + A + V
Sbjct: 229 GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 288
Query: 179 SCLTTAPRTDQLEGMLVHRRPLNEVHANEQETMAVDSPVKREATPAGPRA 228
CL +L+G ++ ++ + +++ A SP A AG A
Sbjct: 289 ECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAA 338
>AJ785968-1|CAH05056.1| 396|Homo sapiens PDPK2 protein protein.
Length = 396
Score = 113 bits (272), Expect = 1e-24
Identities = 60/173 (34%), Positives = 95/173 (54%), Gaps = 8/173 (4%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++I + E TRFY +I+ ++YLH K IIHRDLK N+ L++D++++I DFG A +
Sbjct: 145 RKIGSFDETCTRFYTAEIVSALEYLHGKGIIHRDLKPENILLNEDMYIQITDFGTAKVLS 204
Query: 65 YEGE--RKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTY 122
E + R + GT Y++PE+LT+K D+W+LGCI+Y L+ G PPF +
Sbjct: 205 PESKQARANSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIF 264
Query: 123 KRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDK------LLQHEFFSS 169
++I + EY P A ++ L + +R ++ L H FF S
Sbjct: 265 QKIIKLEYDFPEKFFPKARDLVEKLLVLDATKRLGCEEMEGYGPLKAHPFFES 317
>AF415197-1|AAM33514.1| 566|Homo sapiens
calcium/calmodulin-dependent protein kinase II gamma
protein.
Length = 566
Score = 113 bits (272), Expect = 1e-24
Identities = 75/230 (32%), Positives = 113/230 (49%), Gaps = 12/230 (5%)
Query: 11 TEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLH---VKIGDFGLAARIEYEG 67
+E + +HQIL V ++H I+HRDLK NL L VK+ DFGLA ++ E
Sbjct: 87 SEADASHCIHQILESVNHIHQHDIVHRDLKPENLLLASKCKGAAVKLADFGLAIEVQGEQ 146
Query: 68 ERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQ 127
+ GTP Y++PE+L K + VDIW+ G I+Y LLVG PPF Y++IK
Sbjct: 147 QAWFGFAGTPGYLSPEVLRKDPYGKPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKA 206
Query: 128 CEYRIPS----SLRKPAASMIVLQLQSNPARRPSVDKLLQHEFFSSGILPAGL-----PV 178
Y PS ++ A ++I L NPA+R + D+ L+H + A + V
Sbjct: 207 GAYDFPSPEWDTVTPEAKNLINQMLTINPAKRITADQALKHPWVCQRSTVASMMHRQETV 266
Query: 179 SCLTTAPRTDQLEGMLVHRRPLNEVHANEQETMAVDSPVKREATPAGPRA 228
CL +L+G ++ ++ + +++ A SP A AG A
Sbjct: 267 ECLRKFNARRKLKGAILTTMLVSRNFSVGRQSSAPASPAASAAGLAGQAA 316
>AF004022-1|AAB65786.1| 347|Homo sapiens protein kinase protein.
Length = 347
Score = 113 bits (272), Expect = 1e-24
Identities = 59/166 (35%), Positives = 97/166 (58%), Gaps = 6/166 (3%)
Query: 2 ELHKRIKAITEPET---RFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFG 58
ELHK E T R M ++ + Y H K++IHRD+K NL L +KI DFG
Sbjct: 165 ELHKTC-TFDEQRTATVRRIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFG 223
Query: 59 LAARIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTL 118
+ + R++T+CGT +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++
Sbjct: 224 WS--VHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASH 281
Query: 119 KDTYKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+TY+RI + + + P+S+ A +I L+ NP+ R + ++ H
Sbjct: 282 NETYRRIVKVDLKFPASVPTGAQDLISKLLRHNPSERLPLAQVSAH 327
>AF015254-1|AAC98891.1| 347|Homo sapiens serine/threonine kinase
protein.
Length = 347
Score = 113 bits (271), Expect = 2e-24
Identities = 53/149 (35%), Positives = 91/149 (61%), Gaps = 2/149 (1%)
Query: 16 RFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGERKQTLCG 75
R M ++ + Y H K++IHRD+K NL L +KI DFG + + R++T+CG
Sbjct: 181 RAVMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWS--VHAPSLRRKTMCG 238
Query: 76 TPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYRIPSS 135
T +Y+ PE++ + H+ +VD+W +G + Y LLVG PPFE+++ +TY+RI + + + P+S
Sbjct: 239 TLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPAS 298
Query: 136 LRKPAASMIVLQLQSNPARRPSVDKLLQH 164
+ A +I L+ NP+ R + ++ H
Sbjct: 299 VPTGAQDLISKLLRHNPSERLPLAQVSAH 327
>M55284-1|AAA60100.1| 682|Homo sapiens protein kinase C-L protein.
Length = 682
Score = 112 bits (270), Expect = 2e-24
Identities = 55/151 (36%), Positives = 82/151 (54%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++ + E RFY +I+ + +LH K II+RDLKL N+ LD + H K+ DFG+
Sbjct: 445 QKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI 504
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
G T CGTP+YIAPEIL + + VD W++G ++Y +L G PFE D ++
Sbjct: 505 CNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEA 564
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E P+ L + A ++ + NP R
Sbjct: 565 ILNDEVVYPTWLHEDATGILKSFMTKNPTMR 595
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 112 bits (270), Expect = 2e-24
Identities = 57/160 (35%), Positives = 94/160 (58%), Gaps = 6/160 (3%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++I+HRDLK NL LD+++++KI DFG + GE
Sbjct: 114 LNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFK-SGEL 172
Query: 70 KQTLCGTPNYIAPEILTKKGHSFE---VDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIK 126
T CG+P Y APE+ +G +E +DIWS+G ++Y L+ G PF+ TL +R+
Sbjct: 173 LATWCGSPPYAAPEVF--EGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVL 230
Query: 127 QCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEF 166
+ +RIP + + +I L +P++R ++ ++ +H++
Sbjct: 231 EGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKW 270
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 112 bits (270), Expect = 2e-24
Identities = 57/160 (35%), Positives = 94/160 (58%), Gaps = 6/160 (3%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++I+HRDLK NL LD+++++KI DFG + GE
Sbjct: 114 LNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFK-SGEL 172
Query: 70 KQTLCGTPNYIAPEILTKKGHSFE---VDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIK 126
T CG+P Y APE+ +G +E +DIWS+G ++Y L+ G PF+ TL +R+
Sbjct: 173 LATWCGSPPYAAPEVF--EGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVL 230
Query: 127 QCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEF 166
+ +RIP + + +I L +P++R ++ ++ +H++
Sbjct: 231 EGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKW 270
>BC037268-1|AAH37268.1| 683|Homo sapiens protein kinase C, eta
protein.
Length = 683
Score = 112 bits (270), Expect = 2e-24
Identities = 55/151 (36%), Positives = 82/151 (54%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
++ + E RFY +I+ + +LH K II+RDLKL N+ LD + H K+ DFG+
Sbjct: 446 QKSRRFDEARARFYAAEIISALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGI 505
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
G T CGTP+YIAPEIL + + VD W++G ++Y +L G PFE D ++
Sbjct: 506 CNGVTTATFCGTPDYIAPEILQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEA 565
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARR 155
I E P+ L + A ++ + NP R
Sbjct: 566 ILNDEVVYPTWLHEDATGILKSFMTKNPTMR 596
>AY987010-1|AAX88805.1| 393|Homo sapiens serum/glucocorticoid
regulated kinase 2 protein.
Length = 393
Score = 112 bits (270), Expect = 2e-24
Identities = 59/168 (35%), Positives = 85/168 (50%), Gaps = 4/168 (2%)
Query: 5 KRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIE 64
+R + EP RFY ++ + YLHS II+RDLK N+ LD HV + DFGL
Sbjct: 152 QRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGV 211
Query: 65 YEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKR 124
+ T CGTP Y+APE+L K+ + VD W LG ++Y +L G PPF + + Y+
Sbjct: 212 EPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYEN 271
Query: 125 IKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVD----KLLQHEFFS 168
I +IP A ++ L + +RP ++ H FFS
Sbjct: 272 ILHQPLQIPGGRTVAACDLLQSLLHKDQRQRPGSKADFLEIKNHVFFS 319
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 112 bits (270), Expect = 2e-24
Identities = 57/160 (35%), Positives = 94/160 (58%), Gaps = 6/160 (3%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++I+HRDLK NL LD+++++KI DFG + GE
Sbjct: 112 LNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFK-SGEL 170
Query: 70 KQTLCGTPNYIAPEILTKKGHSFE---VDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIK 126
T CG+P Y APE+ +G +E +DIWS+G ++Y L+ G PF+ TL +R+
Sbjct: 171 LATWCGSPPYAAPEVF--EGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVL 228
Query: 127 QCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEF 166
+ +RIP + + +I L +P++R ++ ++ +H++
Sbjct: 229 EGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKW 268
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 112 bits (270), Expect = 2e-24
Identities = 57/160 (35%), Positives = 94/160 (58%), Gaps = 6/160 (3%)
Query: 10 ITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAARIEYEGER 69
+ E E R QIL V Y H ++I+HRDLK NL LD+++++KI DFG + GE
Sbjct: 138 LNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFK-SGEL 196
Query: 70 KQTLCGTPNYIAPEILTKKGHSFE---VDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIK 126
T CG+P Y APE+ +G +E +DIWS+G ++Y L+ G PF+ TL +R+
Sbjct: 197 LATWCGSPPYAAPEVF--EGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVL 254
Query: 127 QCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQHEF 166
+ +RIP + + +I L +P++R ++ ++ +H++
Sbjct: 255 EGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKW 294
>BC075064-1|AAH75064.2| 275|Homo sapiens AURKC protein protein.
Length = 275
Score = 112 bits (269), Expect = 3e-24
Identities = 58/163 (35%), Positives = 95/163 (58%), Gaps = 3/163 (1%)
Query: 2 ELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAA 61
EL K K + E T + ++ + Y H K++IHRD+K NL L VKI DFG +
Sbjct: 97 ELQKSEK-LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS- 154
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDT 121
+ R++T+CGT +Y+ PE++ + + +VD+W +G + Y LLVG PPFE+++ +T
Sbjct: 155 -VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSET 213
Query: 122 YKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
Y+RI + + R P S+ A +I L+ P R + ++L+H
Sbjct: 214 YRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKH 256
>AY714054-1|AAU04399.1| 306|Homo sapiens aurora-C protein.
Length = 306
Score = 112 bits (269), Expect = 3e-24
Identities = 58/163 (35%), Positives = 95/163 (58%), Gaps = 3/163 (1%)
Query: 2 ELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAA 61
EL K K + E T + ++ + Y H K++IHRD+K NL L VKI DFG +
Sbjct: 128 ELQKSEK-LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS- 185
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDT 121
+ R++T+CGT +Y+ PE++ + + +VD+W +G + Y LLVG PPFE+++ +T
Sbjct: 186 -VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSET 244
Query: 122 YKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
Y+RI + + R P S+ A +I L+ P R + ++L+H
Sbjct: 245 YRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKH 287
>AY661554-1|AAT64422.1| 290|Homo sapiens aurora/Ipl1-related kinase
3 transcript variant 1 protein.
Length = 290
Score = 112 bits (269), Expect = 3e-24
Identities = 58/163 (35%), Positives = 95/163 (58%), Gaps = 3/163 (1%)
Query: 2 ELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAA 61
EL K K + E T + ++ + Y H K++IHRD+K NL L VKI DFG +
Sbjct: 112 ELQKSEK-LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS- 169
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDT 121
+ R++T+CGT +Y+ PE++ + + +VD+W +G + Y LLVG PPFE+++ +T
Sbjct: 170 -VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSET 228
Query: 122 YKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
Y+RI + + R P S+ A +I L+ P R + ++L+H
Sbjct: 229 YRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKH 271
>AF054621-1|AAC25955.1| 309|Homo sapiens serine/threonine kinase
AIE2 protein.
Length = 309
Score = 112 bits (269), Expect = 3e-24
Identities = 58/163 (35%), Positives = 95/163 (58%), Gaps = 3/163 (1%)
Query: 2 ELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAA 61
EL K K + E T + ++ + Y H K++IHRD+K NL L VKI DFG +
Sbjct: 131 ELQKSEK-LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS- 188
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDT 121
+ R++T+CGT +Y+ PE++ + + +VD+W +G + Y LLVG PPFE+++ +T
Sbjct: 189 -VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSET 247
Query: 122 YKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
Y+RI + + R P S+ A +I L+ P R + ++L+H
Sbjct: 248 YRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKH 290
>AB017332-1|BAA76292.1| 309|Homo sapiens Aurora/Ipl1-related kinase
3 protein.
Length = 309
Score = 112 bits (269), Expect = 3e-24
Identities = 58/163 (35%), Positives = 95/163 (58%), Gaps = 3/163 (1%)
Query: 2 ELHKRIKAITEPETRFYMHQILLGVQYLHSKRIIHRDLKLGNLFLDDDLHVKIGDFGLAA 61
EL K K + E T + ++ + Y H K++IHRD+K NL L VKI DFG +
Sbjct: 131 ELQKSEK-LDEQRTATIIEELADALTYCHDKKVIHRDIKPENLLLGFRGEVKIADFGWS- 188
Query: 62 RIEYEGERKQTLCGTPNYIAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDT 121
+ R++T+CGT +Y+ PE++ + + +VD+W +G + Y LLVG PPFE+++ +T
Sbjct: 189 -VHTPSLRRKTMCGTLDYLPPEMIEGRTYDEKVDLWCIGVLCYELLVGYPPFESASHSET 247
Query: 122 YKRIKQCEYRIPSSLRKPAASMIVLQLQSNPARRPSVDKLLQH 164
Y+RI + + R P S+ A +I L+ P R + ++L+H
Sbjct: 248 YRRILKVDVRFPLSMPLGARDLISRLLRYQPLERLPLAQILKH 290
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 111 bits (268), Expect = 4e-24
Identities = 55/151 (36%), Positives = 89/151 (58%), Gaps = 2/151 (1%)
Query: 21 QILLGVQYLHSKRIIHRDLKLGNLFLDDD-LHVKIGDFGLAARIEYEGERKQTLCGTPNY 79
QI LG++++H ++I+HRD+K N+FL + + K+GDFG+A + E +T GTP Y
Sbjct: 111 QISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYY 170
Query: 80 IAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYR-IPSSLRK 138
++PEI K ++ + DIWSLGC++Y L K PFE + L+ +I Q + I +
Sbjct: 171 LSPEICQNKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSR 230
Query: 139 PAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
S+I Q +P RPS++ +L+ F +
Sbjct: 231 ELHSLISQLFQVSPRDRPSINSILKRPFLEN 261
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 111 bits (268), Expect = 4e-24
Identities = 55/151 (36%), Positives = 89/151 (58%), Gaps = 2/151 (1%)
Query: 21 QILLGVQYLHSKRIIHRDLKLGNLFLDDD-LHVKIGDFGLAARIEYEGERKQTLCGTPNY 79
QI LG++++H ++I+HRD+K N+FL + + K+GDFG+A + E +T GTP Y
Sbjct: 111 QISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYY 170
Query: 80 IAPEILTKKGHSFEVDIWSLGCIMYTLLVGKPPFETSTLKDTYKRIKQCEYR-IPSSLRK 138
++PEI K ++ + DIWSLGC++Y L K PFE + L+ +I Q + I +
Sbjct: 171 LSPEICQNKPYNNKTDIWSLGCVLYELCTLKHPFEGNNLQQLVLKICQAHFAPISPGFSR 230
Query: 139 PAASMIVLQLQSNPARRPSVDKLLQHEFFSS 169
S+I Q +P RPS++ +L+ F +
Sbjct: 231 ELHSLISQLFQVSPRDRPSINSILKRPFLEN 261
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.137 0.411
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 69,709,473
Number of Sequences: 224733
Number of extensions: 3040731
Number of successful extensions: 11388
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 2476
Number of HSP's successfully gapped in prelim test: 314
Number of HSP's that attempted gapping in prelim test: 5810
Number of HSP's gapped (non-prelim): 3225
length of query: 459
length of database: 73,234,838
effective HSP length: 92
effective length of query: 367
effective length of database: 52,559,402
effective search space: 19289300534
effective search space used: 19289300534
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 67 (31.1 bits)
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