Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA003111-TA|BGIBMGA003111-PA|IPR001563|Peptidase S10,
serine carboxypeptidase
(402 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF106704-1|AAG37991.2| 476|Homo sapiens putative serine carboxy... 173 7e-43
AY358549-1|AAQ88913.1| 476|Homo sapiens CPVL protein. 172 2e-42
BC016838-1|AAH16838.1| 476|Homo sapiens carboxypeptidase, vitel... 171 5e-42
AF282617-1|AAG14348.1| 476|Homo sapiens vitellogenic carboxypep... 170 9e-42
AK075433-1|BAC11618.1| 476|Homo sapiens protein ( Homo sapiens ... 169 1e-41
AC005162-1|AAC23787.1| 295|Homo sapiens unknown protein. 125 2e-28
BC072405-1|AAH72405.1| 452|Homo sapiens serine carboxypeptidase... 91 8e-18
AY358559-1|AAQ88923.1| 452|Homo sapiens HSCP1 protein. 91 8e-18
AK027373-1|BAB55069.1| 452|Homo sapiens protein ( Homo sapiens ... 91 8e-18
AF282618-1|AAG16692.1| 452|Homo sapiens serine carboxypeptidase... 91 8e-18
M22960-1|AAA36476.1| 480|Homo sapiens protein ( Human protectiv... 67 1e-10
BC093009-1|AAH93009.1| 480|Homo sapiens CTSA protein protein. 67 1e-10
BC000597-1|AAH00597.1| 479|Homo sapiens CTSA protein protein. 67 1e-10
AL008726-16|CAA15501.1| 480|Homo sapiens cathepsin A protein. 67 1e-10
AL008726-15|CAI20250.1| 345|Homo sapiens cathepsin A protein. 67 1e-10
AL008726-14|CAI20249.1| 289|Homo sapiens cathepsin A protein. 67 1e-10
AL008726-13|CAI20248.1| 498|Homo sapiens cathepsin A protein. 67 1e-10
AB209705-1|BAD92942.1| 497|Homo sapiens carrier family 6 , memb... 67 1e-10
AC007096-1|AAS07545.1| 180|Homo sapiens unknown protein. 50 1e-05
AY196345-1|AAO72074.1| 206|Homo sapiens tryptophan hydroxylase ... 32 3.1
X52836-1|CAA37018.1| 444|Homo sapiens protein ( Human mRNA for ... 31 9.5
BC106739-1|AAI06740.1| 444|Homo sapiens tryptophan hydroxylase ... 31 9.5
>AF106704-1|AAG37991.2| 476|Homo sapiens putative serine
carboxypeptidase CPVL protein.
Length = 476
Score = 173 bits (422), Expect = 7e-43
Identities = 104/323 (32%), Positives = 176/323 (54%), Gaps = 17/323 (5%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
ML+IDNPVG GFSFTD G+ N D+ A DLY+AL QF IFPE + Y+ GESYAG
Sbjct: 148 MLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAG 207
Query: 61 RYIPPFAMKLAEQDLN-IGTFEVNLQGIIMGNPVVDRYS-VANYTSTFQQWGLIDTQGAM 118
+Y+P A + LN + ++NL GI +G+ D S + Y Q GL+D +
Sbjct: 208 KYVPAIAHLI--HSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKK 265
Query: 119 SVKSLQDQYIKAILDGDASAAYDLRDQLL-YKLT-------KITLQNQFFNVLKSNKDLT 170
+ + I+ I + A+++ D+LL LT +T + ++N L+ +
Sbjct: 266 YFQKQCHECIEHIRKQNWLEAFEILDKLLDGDLTSDPSYFQNVTGCSNYYNFLRCTEPED 325
Query: 171 LSEFAAYLQKSTVKEALHVGDTDFSFINTTVDLELKSDFLTDIGGTVTKLLEHCKVLIYC 230
+ +L V++A+HVG+ F+ T V+ L+ D + + +T+++ + KVLIY
Sbjct: 326 QLYYVKFLSLPEVRQAIHVGNQTFN-DGTIVEKYLREDTVQSVKPWLTEIMNNYKVLIYN 384
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLW-LHK--NVVAGYTKSGGGFTEVLV 287
GQLD+ + ++ W + + +A +++W + K + VAGY + G F +V++
Sbjct: 385 GQLDIIVAAALT-EHSLMGMDWKGSQEYKKAEKKVWKIFKSDSEVAGYIRQAGDFHQVII 443
Query: 288 KGAGHLVPIDKPEELYELISWFV 310
+G GH++P D+P +++I+ F+
Sbjct: 444 RGGGHILPYDQPLRAFDMINRFI 466
>AY358549-1|AAQ88913.1| 476|Homo sapiens CPVL protein.
Length = 476
Score = 172 bits (418), Expect = 2e-42
Identities = 104/323 (32%), Positives = 175/323 (54%), Gaps = 17/323 (5%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
ML+IDNPVG GFSFTD G+ N D+ A DLY+AL QF IFPE + Y+ GESYAG
Sbjct: 148 MLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAG 207
Query: 61 RYIPPFAMKLAEQDLN-IGTFEVNLQGIIMGNPVVDRYS-VANYTSTFQQWGLIDTQGAM 118
+Y+P A + LN + ++NL GI +G+ D S + Y Q GL+D +
Sbjct: 208 KYVPAIAHLI--HSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKK 265
Query: 119 SVKSLQDQYIKAILDGDASAAYDLRDQLL-YKLT-------KITLQNQFFNVLKSNKDLT 170
+ + I+ I + A+++ D+LL LT +T + ++N L+ +
Sbjct: 266 YFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTSDPSYFQNVTGCSNYYNFLRCTEPED 325
Query: 171 LSEFAAYLQKSTVKEALHVGDTDFSFINTTVDLELKSDFLTDIGGTVTKLLEHCKVLIYC 230
+ +L V++A+HVG+ F+ T V+ L+ D + + +T+++ + KVLIY
Sbjct: 326 QLYYVKFLSLPEVRQAIHVGNQTFN-DGTIVEKYLREDTVQSVKPWLTEIMNNYKVLIYN 384
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLW-LHK--NVVAGYTKSGGGFTEVLV 287
GQLD+ + + W + + +A +++W + K + VAGY + G F +V++
Sbjct: 385 GQLDIIVAAALT-ERSLMGMDWKGSQEYKKAEKKVWKIFKSDSEVAGYIRQAGDFHQVII 443
Query: 288 KGAGHLVPIDKPEELYELISWFV 310
+G GH++P D+P +++I+ F+
Sbjct: 444 RGGGHILPYDQPLRAFDMINRFI 466
>BC016838-1|AAH16838.1| 476|Homo sapiens carboxypeptidase,
vitellogenic-like protein.
Length = 476
Score = 171 bits (415), Expect = 5e-42
Identities = 104/323 (32%), Positives = 175/323 (54%), Gaps = 17/323 (5%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
ML+IDNPVG GFSFTD G+ N D+ A DLY+AL QF IFPE + Y+ GESYAG
Sbjct: 148 MLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAG 207
Query: 61 RYIPPFAMKLAEQDLN-IGTFEVNLQGIIMGNPVVDRYS-VANYTSTFQQWGLIDTQGAM 118
+Y+P A + LN + ++NL GI +G+ D S + Y Q GL+D +
Sbjct: 208 KYVPAIAHLI--HSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKK 265
Query: 119 SVKSLQDQYIKAILDGDASAAYDLRDQLL-YKLT-------KITLQNQFFNVLKSNKDLT 170
+ + I+ I + A+++ D+LL LT +T + ++N L+ +
Sbjct: 266 YFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTSDPSYFQNVTGCSNYYNFLRCTEPED 325
Query: 171 LSEFAAYLQKSTVKEALHVGDTDFSFINTTVDLELKSDFLTDIGGTVTKLLEHCKVLIYC 230
+ +L V++A+HVG+ F+ T V+ L+ D + + +T+++ + KVLIY
Sbjct: 326 QLYYVKFLSLPEVRQAIHVGNQTFN-DGTIVEKYLREDTVQSVKPWLTEIMNNYKVLIYN 384
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLW-LHK--NVVAGYTKSGGGFTEVLV 287
GQLD+ + + W + + +A +++W + K + VAGY + G F +V++
Sbjct: 385 GQLDIIVAAALT-ERSLMGMDWKGSQEYKKAEKKVWKIFKSDSEVAGYIRQVGDFHQVII 443
Query: 288 KGAGHLVPIDKPEELYELISWFV 310
+G GH++P D+P +++I+ F+
Sbjct: 444 RGGGHILPYDQPLRAFDMINRFI 466
>AF282617-1|AAG14348.1| 476|Homo sapiens vitellogenic
carboxypeptidase-like protein protein.
Length = 476
Score = 170 bits (413), Expect = 9e-42
Identities = 102/323 (31%), Positives = 173/323 (53%), Gaps = 17/323 (5%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
ML+IDNPVG GFSFTD G+ N D+ A DLY+AL QF IFPE + Y+ GESYAG
Sbjct: 148 MLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAG 207
Query: 61 RYIPPFAMKLAEQDLN-IGTFEVNLQGIIMGNPVVDRYS-VANYTSTFQQWGLIDTQGAM 118
+Y+P A + LN + ++NL GI +G+ D S + Y Q GL+D +
Sbjct: 208 KYVPAIAHLI--HSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKK 265
Query: 119 SVKSLQDQYIKAILDGDASAAYDLRDQLL-YKLT-------KITLQNQFFNVLKSNKDLT 170
+ + I+ I + A+++ D+LL LT +T + ++N L+ +
Sbjct: 266 YFQKQCHECIEHIRKQNWLEAFEILDKLLDGDLTSDPSYFQNVTGCSNYYNFLRCTEPED 325
Query: 171 LSEFAAYLQKSTVKEALHVGDTDFSFINTTVDLELKSDFLTDIGGTVTKLLEHCKVLIYC 230
+ +L V++A+HVG+ F+ T V+ L+ D + + +T+++ + KVLIY
Sbjct: 326 QLYYVKFLSLPEVRQAIHVGNQTFN-DGTIVEKYLREDTVQSVKPWLTEIMNNYKVLIYN 384
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLW---LHKNVVAGYTKSGGGFTEVLV 287
GQLD+ + ++ W + + +A +++W + VAGY + G +V++
Sbjct: 385 GQLDIIVAAALT-EHSLMGMDWKGSQEYKKAEKKVWKILKSDSEVAGYIRQAGDSHQVII 443
Query: 288 KGAGHLVPIDKPEELYELISWFV 310
+G GH++P D+P +++I+ F+
Sbjct: 444 RGGGHILPYDQPLRAFDMINRFI 466
>AK075433-1|BAC11618.1| 476|Homo sapiens protein ( Homo sapiens
cDNA PSEC0124 fis, clone PLACE1003378, highly similar to
Probable serine carboxypeptidase CPVLprecursor (EC
3.4.16.-). ).
Length = 476
Score = 169 bits (411), Expect = 1e-41
Identities = 104/323 (32%), Positives = 174/323 (53%), Gaps = 17/323 (5%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
ML+IDNPVG GFSFTD G+ N D+ A DLY+AL QF IFPE + Y+ GESYAG
Sbjct: 148 MLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAG 207
Query: 61 RYIPPFAMKLAEQDLN-IGTFEVNLQGIIMGNPVVDRYS-VANYTSTFQQWGLIDTQGAM 118
+Y+P A + LN + ++NL GI +G+ D S + Y Q GL+D +
Sbjct: 208 KYVPAIAHLI--HSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKK 265
Query: 119 SVKSLQDQYIKAILDGDASAAYDLRDQLL-YKLT-------KITLQNQFFNVLKSNKDLT 170
+ + I+ I + A ++ D+LL LT +T + ++N L+ +
Sbjct: 266 YFQKQCHECIEHIRKQNWFEALEILDKLLDGDLTSDPSYFQNVTGCSNYYNFLRCTEPED 325
Query: 171 LSEFAAYLQKSTVKEALHVGDTDFSFINTTVDLELKSDFLTDIGGTVTKLLEHCKVLIYC 230
+ +L V++A+HVG+ F+ T V+ L+ D + + +T+++ + KVLIY
Sbjct: 326 QLYYVKFLSLPEVRQAIHVGNQTFN-DGTIVEKYLREDTVQSVKPWLTEIMNNYKVLIYN 384
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLW-LHK--NVVAGYTKSGGGFTEVLV 287
GQLD+ + + W + + +A +++W + K + VAGY + G F +V++
Sbjct: 385 GQLDIIVAAALT-ERSLMGMDWKGSQEYKKAEKKVWKIFKSDSEVAGYIRQVGDFHQVII 443
Query: 288 KGAGHLVPIDKPEELYELISWFV 310
+G GH++P D+P +++I+ F+
Sbjct: 444 RGGGHILPYDQPLRAFDMINRFI 466
>AC005162-1|AAC23787.1| 295|Homo sapiens unknown protein.
Length = 295
Score = 125 bits (302), Expect = 2e-28
Identities = 83/289 (28%), Positives = 150/289 (51%), Gaps = 17/289 (5%)
Query: 35 ALKQFLIIFPELRTAPLYIAGESYAGRYIPPFAMKLAEQDLN-IGTFEVNLQGIIMGNPV 93
AL QF IFPE + Y+ GESYAG+Y+P A + LN + ++NL GI +G+
Sbjct: 1 ALIQFFQIFPEYKNNDFYVTGESYAGKYVPAIAHLI--HSLNPVREVKINLNGIAIGDGY 58
Query: 94 VDRYSV-ANYTSTFQQWGLIDTQGAMSVKSLQDQYIKAILDGDASAAYDLRDQLLY-KLT 151
D S+ Y Q GL+D + + + I+ I + A+++ D+LL LT
Sbjct: 59 SDPESIIGGYAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLT 118
Query: 152 K-------ITLQNQFFNVLKSNKDLTLSEFAAYLQKSTVKEALHVGDTDFSFINTTVDLE 204
+T + ++N L+ + + +L V++A+HVG+ F+ T V+
Sbjct: 119 SDPSYFQNVTGCSNYYNFLRCTEPEDQLYYVKFLSLPEVRQAIHVGNQTFND-GTIVEKY 177
Query: 205 LKSDFLTDIGGTVTKLLEHCKVLIYCGQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRR 264
L+ D + + +T+++ + KVLIY GQLD+ + + W + + +A ++
Sbjct: 178 LREDTVQSVKPWLTEIMNNYKVLIYNGQLDIIVAAALTERSLMGM-DWKGSQEYKKAEKK 236
Query: 265 LW-LHKN--VVAGYTKSGGGFTEVLVKGAGHLVPIDKPEELYELISWFV 310
+W + K+ VAGY + G F +V+++G GH++P D+P +++I+ F+
Sbjct: 237 VWKIFKSDSEVAGYIRQAGDFHQVIIRGGGHILPYDQPLRAFDMINRFI 285
>BC072405-1|AAH72405.1| 452|Homo sapiens serine carboxypeptidase 1
protein.
Length = 452
Score = 90.6 bits (215), Expect = 8e-18
Identities = 85/328 (25%), Positives = 144/328 (43%), Gaps = 31/328 (9%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+LF+DNPVG GFS+ + + + K++ ASD+ LK F E +T P YI ESY G
Sbjct: 111 LLFVDNPVGTGFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGG 170
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGNPVVDRY-SVANYTSTFQQWGLIDTQGAMS 119
+ ++L + + GT + N G+ +G+ + SV ++ L++ +G
Sbjct: 171 KMAAGIGLELYKA-IQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAE 229
Query: 120 VKSLQDQYIKAILDGDASAAYDLRDQLLYKLTKITLQNQFFNVL-KSNKDLTLS---EFA 175
V + +Q + A+ G A +L + + + T F+N+L KS T+ EF
Sbjct: 230 VSKVAEQVLNAVNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFT 289
Query: 176 --------------------AYLQKSTVKEALHVGDTDFSFIN--TTVDLELKSDFLTDI 213
+ L +++ L + D S+ T V + ++ DF+ +
Sbjct: 290 QSHLVCLCQRHVRHLQRDALSQLMNGPIRKKLKIIPEDQSWGGQATNVFVNMEEDFMKPV 349
Query: 214 GGTVTKLLE-HCKVLIYCGQLDLTAPCV-QSAQYRRRYWQWNKKELFLRAPRRLWLHKNV 271
V +LLE V +Y GQLDL + Q A R+ W K L+ K++
Sbjct: 350 ISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQLKWKALYSDPKSL 409
Query: 272 -VAGYTKSGGGFTEVLVKGAGHLVPIDK 298
+ + KS + AGH+VP D+
Sbjct: 410 ETSAFVKSYKNLAFYWILKAGHMVPSDQ 437
>AY358559-1|AAQ88923.1| 452|Homo sapiens HSCP1 protein.
Length = 452
Score = 90.6 bits (215), Expect = 8e-18
Identities = 85/328 (25%), Positives = 144/328 (43%), Gaps = 31/328 (9%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+LF+DNPVG GFS+ + + + K++ ASD+ LK F E +T P YI ESY G
Sbjct: 111 LLFVDNPVGTGFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGG 170
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGNPVVDRY-SVANYTSTFQQWGLIDTQGAMS 119
+ ++L + + GT + N G+ +G+ + SV ++ L++ +G
Sbjct: 171 KMAAGIGLELYKA-IQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAE 229
Query: 120 VKSLQDQYIKAILDGDASAAYDLRDQLLYKLTKITLQNQFFNVL-KSNKDLTLS---EFA 175
V + +Q + A+ G A +L + + + T F+N+L KS T+ EF
Sbjct: 230 VSKVAEQVLNAVNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFT 289
Query: 176 --------------------AYLQKSTVKEALHVGDTDFSFIN--TTVDLELKSDFLTDI 213
+ L +++ L + D S+ T V + ++ DF+ +
Sbjct: 290 QSHLVCLCQRHVRHLQRDALSQLMNGPIRKKLKIIPEDQSWGGQATNVFVNMEEDFMKPV 349
Query: 214 GGTVTKLLE-HCKVLIYCGQLDLTAPCV-QSAQYRRRYWQWNKKELFLRAPRRLWLHKNV 271
V +LLE V +Y GQLDL + Q A R+ W K L+ K++
Sbjct: 350 ISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQLKWKALYSDPKSL 409
Query: 272 -VAGYTKSGGGFTEVLVKGAGHLVPIDK 298
+ + KS + AGH+VP D+
Sbjct: 410 ETSAFVKSYKNLAFYWILKAGHMVPSDQ 437
>AK027373-1|BAB55069.1| 452|Homo sapiens protein ( Homo sapiens
cDNA FLJ14467 fis, clone MAMMA1000672, weakly similar to
VITELLOGENIC CARBOXYPEPTIDASE PRECURSOR (EC 3.4.16.-).
).
Length = 452
Score = 90.6 bits (215), Expect = 8e-18
Identities = 85/328 (25%), Positives = 144/328 (43%), Gaps = 31/328 (9%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+LF+DNPVG GFS+ + + + K++ ASD+ LK F E +T P YI ESY G
Sbjct: 111 LLFVDNPVGTGFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGG 170
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGNPVVDRY-SVANYTSTFQQWGLIDTQGAMS 119
+ ++L + + GT + N G+ +G+ + SV ++ L++ +G
Sbjct: 171 KMAAGIGLELYKA-IQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAE 229
Query: 120 VKSLQDQYIKAILDGDASAAYDLRDQLLYKLTKITLQNQFFNVL-KSNKDLTLS---EFA 175
V + +Q + A+ G A +L + + + T F+N+L KS T+ EF
Sbjct: 230 VSKVAEQVLNAVNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFT 289
Query: 176 --------------------AYLQKSTVKEALHVGDTDFSFIN--TTVDLELKSDFLTDI 213
+ L +++ L + D S+ T V + ++ DF+ +
Sbjct: 290 QSHLVCLCQRHVRHLQRDALSQLMNGPIRKKLKIIPEDQSWGGQATNVFVNMEEDFMKPV 349
Query: 214 GGTVTKLLE-HCKVLIYCGQLDLTAPCV-QSAQYRRRYWQWNKKELFLRAPRRLWLHKNV 271
V +LLE V +Y GQLDL + Q A R+ W K L+ K++
Sbjct: 350 ISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQLKWKALYSDPKSL 409
Query: 272 -VAGYTKSGGGFTEVLVKGAGHLVPIDK 298
+ + KS + AGH+VP D+
Sbjct: 410 ETSAFVKSYKNLAFYWILKAGHMVPSDQ 437
>AF282618-1|AAG16692.1| 452|Homo sapiens serine carboxypeptidase 1
precursor protein protein.
Length = 452
Score = 90.6 bits (215), Expect = 8e-18
Identities = 85/328 (25%), Positives = 144/328 (43%), Gaps = 31/328 (9%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+LF+DNPVG GFS+ + + + K++ ASD+ LK F E +T P YI ESY G
Sbjct: 111 LLFVDNPVGTGFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFSESYGG 170
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGNPVVDRY-SVANYTSTFQQWGLIDTQGAMS 119
+ ++L + + GT + N G+ +G+ + SV ++ L++ +G
Sbjct: 171 KMAAGIGLELYKA-IQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDKGLAE 229
Query: 120 VKSLQDQYIKAILDGDASAAYDLRDQLLYKLTKITLQNQFFNVL-KSNKDLTLS---EFA 175
V + +Q + A+ G A +L + + + T F+N+L KS T+ EF
Sbjct: 230 VSKVAEQVLNAVNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESSLEFT 289
Query: 176 --------------------AYLQKSTVKEALHVGDTDFSFIN--TTVDLELKSDFLTDI 213
+ L +++ L + D S+ T V + ++ DF+ +
Sbjct: 290 QSHLVCLCQRHVRHLQRDALSQLMNGPIRKKLKIIPEDQSWGGQATNVFVNMEEDFMKPV 349
Query: 214 GGTVTKLLE-HCKVLIYCGQLDLTAPCV-QSAQYRRRYWQWNKKELFLRAPRRLWLHKNV 271
V +LLE V +Y GQLDL + Q A R+ W K L+ K++
Sbjct: 350 ISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWPELPKFSQLKWKALYSDPKSL 409
Query: 272 -VAGYTKSGGGFTEVLVKGAGHLVPIDK 298
+ + KS + AGH+VP D+
Sbjct: 410 ETSAFVKSYKNLAFYWILKAGHMVPSDQ 437
>M22960-1|AAA36476.1| 480|Homo sapiens protein ( Human protective
protein mRNA, complete cds. ).
Length = 480
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+L++++P G GFS++D + N E A + AL+ F +FPE + L++ GESYAG
Sbjct: 123 VLYLESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAG 181
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGN 91
YIP A+ L QD + +NLQG+ +GN
Sbjct: 182 IYIPTLAV-LVMQDPS-----MNLQGLAVGN 206
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 16/148 (10%)
Query: 175 AAYLQKSTVKEALHVGDT--DFSFINTTVDLELKSDFLTDIGGTVTKLLEHCK--VLIYC 230
+ YL V++AL++ + + N V+L+ + + + + KLL K +L+Y
Sbjct: 338 STYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRS-MNSQYLKLLSSQKYQILLYN 396
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLWLHK-----NVVAGYTKSGGGFTEV 285
G +D+ + + W + + RR WL K +AG+ K +
Sbjct: 397 GDVDM------ACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFL 450
Query: 286 LVKGAGHLVPIDKPEELYELISWFVSSR 313
+KGAGH+VP DKP + + S F++ +
Sbjct: 451 TIKGAGHMVPTDKPLAAFTMFSRFLNKQ 478
>BC093009-1|AAH93009.1| 480|Homo sapiens CTSA protein protein.
Length = 480
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+L++++P G GFS++D + N E A + AL+ F +FPE + L++ GESYAG
Sbjct: 123 VLYLESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAG 181
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGN 91
YIP A+ L QD + +NLQG+ +GN
Sbjct: 182 IYIPTLAV-LVMQDPS-----MNLQGLAVGN 206
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 16/148 (10%)
Query: 175 AAYLQKSTVKEALHVGDT--DFSFINTTVDLELKSDFLTDIGGTVTKLLEHCK--VLIYC 230
+ YL V++AL++ + + N V+L+ + + + + KLL K +L+Y
Sbjct: 338 STYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRS-MNSQYLKLLSSQKYQILLYN 396
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLWLHK-----NVVAGYTKSGGGFTEV 285
G +D+ + + W + + RR WL K +AG+ K +
Sbjct: 397 GDVDM------ACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFL 450
Query: 286 LVKGAGHLVPIDKPEELYELISWFVSSR 313
+KGAGH+VP DKP + + S F++ +
Sbjct: 451 TIKGAGHMVPTDKPLAAFTMFSRFLNKQ 478
>BC000597-1|AAH00597.1| 479|Homo sapiens CTSA protein protein.
Length = 479
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+L++++P G GFS++D + N E A + AL+ F +FPE + L++ GESYAG
Sbjct: 122 VLYLESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAG 180
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGN 91
YIP A+ L QD + +NLQG+ +GN
Sbjct: 181 IYIPTLAV-LVMQDPS-----MNLQGLAVGN 205
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 16/148 (10%)
Query: 175 AAYLQKSTVKEALHVGDT--DFSFINTTVDLELKSDFLTDIGGTVTKLLEHCK--VLIYC 230
+ YL V++AL++ + + N V+L+ + + + + KLL K +L+Y
Sbjct: 337 STYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRS-MNSQYLKLLSSQKYQILLYN 395
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLWLHK-----NVVAGYTKSGGGFTEV 285
G +D+ + + W + + RR WL K +AG+ K +
Sbjct: 396 GDVDM------ACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFL 449
Query: 286 LVKGAGHLVPIDKPEELYELISWFVSSR 313
+KGAGH+VP DKP + + S F++ +
Sbjct: 450 TIKGAGHMVPTDKPLAAFTMFSRFLNKQ 477
>AL008726-16|CAA15501.1| 480|Homo sapiens cathepsin A protein.
Length = 480
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+L++++P G GFS++D + N E A + AL+ F +FPE + L++ GESYAG
Sbjct: 123 VLYLESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAG 181
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGN 91
YIP A+ L QD + +NLQG+ +GN
Sbjct: 182 IYIPTLAV-LVMQDPS-----MNLQGLAVGN 206
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 16/148 (10%)
Query: 175 AAYLQKSTVKEALHVGDT--DFSFINTTVDLELKSDFLTDIGGTVTKLLEHCK--VLIYC 230
+ YL V++AL++ + + N V+L+ + + + + KLL K +L+Y
Sbjct: 338 STYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRS-MNSQYLKLLSSQKYQILLYN 396
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLWLHK-----NVVAGYTKSGGGFTEV 285
G +D+ + + W + + RR WL K +AG+ K +
Sbjct: 397 GDVDM------ACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFL 450
Query: 286 LVKGAGHLVPIDKPEELYELISWFVSSR 313
+KGAGH+VP DKP + + S F++ +
Sbjct: 451 TIKGAGHMVPTDKPLAAFTMFSRFLNKQ 478
>AL008726-15|CAI20250.1| 345|Homo sapiens cathepsin A protein.
Length = 345
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+L++++P G GFS++D + N E A + AL+ F +FPE + L++ GESYAG
Sbjct: 106 VLYLESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAG 164
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGN 91
YIP A+ L QD + +NLQG+ +GN
Sbjct: 165 IYIPTLAV-LVMQDPS-----MNLQGLAVGN 189
>AL008726-14|CAI20249.1| 289|Homo sapiens cathepsin A protein.
Length = 289
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+L++++P G GFS++D + N E A + AL+ F +FPE + L++ GESYAG
Sbjct: 123 VLYLESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAG 181
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGN 91
YIP A+ L QD + +NLQG+ +GN
Sbjct: 182 IYIPTLAV-LVMQDPS-----MNLQGLAVGN 206
>AL008726-13|CAI20248.1| 498|Homo sapiens cathepsin A protein.
Length = 498
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+L++++P G GFS++D + N E A + AL+ F +FPE + L++ GESYAG
Sbjct: 141 VLYLESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAG 199
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGN 91
YIP A+ L QD + +NLQG+ +GN
Sbjct: 200 IYIPTLAV-LVMQDPS-----MNLQGLAVGN 224
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 16/148 (10%)
Query: 175 AAYLQKSTVKEALHVGDT--DFSFINTTVDLELKSDFLTDIGGTVTKLLEHCK--VLIYC 230
+ YL V++AL++ + + N V+L+ + + + + KLL K +L+Y
Sbjct: 356 STYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRS-MNSQYLKLLSSQKYQILLYN 414
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLWLHK-----NVVAGYTKSGGGFTEV 285
G +D+ + + W + + RR WL K +AG+ K +
Sbjct: 415 GDVDM------ACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFL 468
Query: 286 LVKGAGHLVPIDKPEELYELISWFVSSR 313
+KGAGH+VP DKP + + S F++ +
Sbjct: 469 TIKGAGHMVPTDKPLAAFTMFSRFLNKQ 496
>AB209705-1|BAD92942.1| 497|Homo sapiens carrier family 6 , member
8 variant protein.
Length = 497
Score = 66.9 bits (156), Expect = 1e-10
Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 7/91 (7%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLYTALKQFLIIFPELRTAPLYIAGESYAG 60
+L++++P G GFS++D + N E A + AL+ F +FPE + L++ GESYAG
Sbjct: 140 VLYLESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAG 198
Query: 61 RYIPPFAMKLAEQDLNIGTFEVNLQGIIMGN 91
YIP A+ L QD + +NLQG+ +GN
Sbjct: 199 IYIPTLAV-LVMQDPS-----MNLQGLAVGN 223
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/148 (25%), Positives = 68/148 (45%), Gaps = 16/148 (10%)
Query: 175 AAYLQKSTVKEALHVGDT--DFSFINTTVDLELKSDFLTDIGGTVTKLLEHCK--VLIYC 230
+ YL V++AL++ + + N V+L+ + + + + KLL K +L+Y
Sbjct: 355 STYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRS-MNSQYLKLLSSQKYQILLYN 413
Query: 231 GQLDLTAPCVQSAQYRRRYWQWNKKELFLRAPRRLWLHK-----NVVAGYTKSGGGFTEV 285
G +D+ + + W + + RR WL K +AG+ K +
Sbjct: 414 GDVDM------ACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFL 467
Query: 286 LVKGAGHLVPIDKPEELYELISWFVSSR 313
+KGAGH+VP DKP + + S F++ +
Sbjct: 468 TIKGAGHMVPTDKPLAAFTMFSRFLNKQ 495
>AC007096-1|AAS07545.1| 180|Homo sapiens unknown protein.
Length = 180
Score = 50.4 bits (115), Expect = 1e-05
Identities = 21/33 (63%), Positives = 24/33 (72%)
Query: 1 MLFIDNPVGAGFSFTDSNDGFVKNMDECASDLY 33
ML+IDNPVG GFSFTD G+ N D+ A DLY
Sbjct: 148 MLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLY 180
>AY196345-1|AAO72074.1| 206|Homo sapiens tryptophan hydroxylase
protein.
Length = 206
Score = 32.3 bits (70), Expect = 3.1
Identities = 36/130 (27%), Positives = 62/130 (47%), Gaps = 16/130 (12%)
Query: 134 GDASAAYDLRDQL--LYKLTKITLQNQFFNVL--KSNKDLTL-SEFAAY----LQKSTVK 184
G AS + L++++ L K KI Q + N+L +S K SEF + + + +
Sbjct: 14 GRASLIFSLKNEVGGLIKALKI-FQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLN 72
Query: 185 EALHV--GDTDFSFINTTVDLELKSDFLTDIGGTVTKL--LEHC--KVLIYCGQLDLTAP 238
+ LH+ T+ +N + LK D + + K+ L+HC +VL+Y +LD P
Sbjct: 73 DILHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHP 132
Query: 239 CVQSAQYRRR 248
+ YR+R
Sbjct: 133 GFKDNVYRKR 142
>X52836-1|CAA37018.1| 444|Homo sapiens protein ( Human mRNA for
tryptophan hydroxylase (EC 1.14.16.4). ).
Length = 444
Score = 30.7 bits (66), Expect = 9.5
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 16/130 (12%)
Query: 134 GDASAAYDLRDQL--LYKLTKITLQNQFFNVL--KSNKDLTL-SEFAAY----LQKSTVK 184
G AS + L++++ L K KI Q + N+L +S K SEF + + + +
Sbjct: 16 GRASLIFSLKNEVGGLIKALKI-FQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLN 74
Query: 185 EALHV--GDTDFSFINTTVDLELKSDFLTDIGGTVTKL--LEHC--KVLIYCGQLDLTAP 238
+ H+ T+ +N + LK D + + K+ L+HC +VL+Y +LD P
Sbjct: 75 DIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHP 134
Query: 239 CVQSAQYRRR 248
+ YR+R
Sbjct: 135 GFKDNVYRKR 144
>BC106739-1|AAI06740.1| 444|Homo sapiens tryptophan hydroxylase 1
(tryptophan 5-monooxygenase) protein.
Length = 444
Score = 30.7 bits (66), Expect = 9.5
Identities = 35/130 (26%), Positives = 61/130 (46%), Gaps = 16/130 (12%)
Query: 134 GDASAAYDLRDQL--LYKLTKITLQNQFFNVL--KSNKDLTL-SEFAAY----LQKSTVK 184
G AS + L++++ L K KI Q + N+L +S K SEF + + + +
Sbjct: 16 GRASLIFSLKNEVGGLIKALKI-FQEKHVNLLHIESRKSKRRNSEFEIFVDCDINREQLN 74
Query: 185 EALHV--GDTDFSFINTTVDLELKSDFLTDIGGTVTKL--LEHC--KVLIYCGQLDLTAP 238
+ H+ T+ +N + LK D + + K+ L+HC +VL+Y +LD P
Sbjct: 75 DIFHLLKSHTNVLSVNLPDNFTLKEDGMETVPWFPKKISDLDHCANRVLMYGSELDADHP 134
Query: 239 CVQSAQYRRR 248
+ YR+R
Sbjct: 135 GFKDNVYRKR 144
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.135 0.398
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 54,222,793
Number of Sequences: 224733
Number of extensions: 2149189
Number of successful extensions: 3542
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3491
Number of HSP's gapped (non-prelim): 28
length of query: 402
length of database: 73,234,838
effective HSP length: 92
effective length of query: 310
effective length of database: 52,559,402
effective search space: 16293414620
effective search space used: 16293414620
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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