Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002845-TA|BGIBMGA002845-PA|IPR009543|Vacuolar protein
sorting-associated protein
(1354 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BX784396-2|CAI19414.1| 4387|Homo sapiens vacuolar protein sortin... 252 6e-66
BX784395-2|CAI19412.1| 4387|Homo sapiens vacuolar protein sortin... 252 6e-66
BX682532-2|CAI23591.1| 4387|Homo sapiens vacuolar protein sortin... 252 6e-66
AL109757-2|CAI22116.1| 4387|Homo sapiens vacuolar protein sortin... 252 6e-66
AL031296-2|CAI23164.1| 4387|Homo sapiens vacuolar protein sortin... 252 6e-66
AL031276-2|CAI19223.1| 4387|Homo sapiens vacuolar protein sortin... 252 6e-66
AB007922-1|BAA32298.3| 3209|Homo sapiens KIAA0453 protein protein. 252 6e-66
AJ608774-1|CAE75586.1| 4388|Homo sapiens VPS13D-1A protein protein. 251 1e-65
BX784396-1|CAI19413.1| 2270|Homo sapiens vacuolar protein sortin... 247 2e-64
BX784395-1|CAI19411.1| 2270|Homo sapiens vacuolar protein sortin... 247 2e-64
BX682532-1|CAI23590.1| 2270|Homo sapiens vacuolar protein sortin... 247 2e-64
AL109757-1|CAI22115.1| 2270|Homo sapiens vacuolar protein sortin... 247 2e-64
AL031296-1|CAI23163.1| 2270|Homo sapiens vacuolar protein sortin... 247 2e-64
AL031276-1|CAI19222.1| 2270|Homo sapiens vacuolar protein sortin... 247 2e-64
AJ608775-1|CAE75587.1| 4363|Homo sapiens VPS13D-2A protein protein. 247 2e-64
BX641035-1|CAE46021.1| 1571|Homo sapiens hypothetical protein pr... 246 3e-64
BC028115-1|AAH28115.1| 1412|Homo sapiens VPS13D protein protein. 180 2e-44
BC051804-1|AAH51804.1| 908|Homo sapiens VPS13D protein protein. 166 5e-40
AK125118-1|BAC86054.1| 944|Homo sapiens protein ( Homo sapiens ... 119 6e-26
AK001481-1|BAA91716.1| 609|Homo sapiens protein ( Homo sapiens ... 55 2e-06
BC041852-1|AAH41852.1| 1246|Homo sapiens VPS13A protein protein. 54 4e-06
AL359204-2|CAI39538.1| 3174|Homo sapiens vacuolar protein sortin... 54 4e-06
AL359204-1|CAI39537.1| 3095|Homo sapiens vacuolar protein sortin... 54 4e-06
AL353710-2|CAH74106.1| 3174|Homo sapiens vacuolar protein sortin... 54 4e-06
AL353710-1|CAH74105.1| 3095|Homo sapiens vacuolar protein sortin... 54 4e-06
AL158159-2|CAI40936.1| 3174|Homo sapiens vacuolar protein sortin... 54 4e-06
AL158159-1|CAI40935.1| 3095|Homo sapiens vacuolar protein sortin... 54 4e-06
AK022967-1|BAB14337.1| 975|Homo sapiens protein ( Homo sapiens ... 54 4e-06
AJ626859-1|CAF25186.1| 3069|Homo sapiens chorein 1D protein. 54 4e-06
AJ608769-1|CAE75581.1| 3135|Homo sapiens chorein 2A protein. 54 4e-06
AF337532-1|AAK61861.1| 3174|Homo sapiens chorea-acanthocytosis p... 54 4e-06
AB054005-1|BAB59128.1| 3095|Homo sapiens chorein protein. 54 4e-06
AB023203-1|BAA76830.1| 1458|Homo sapiens KIAA0986 protein protein. 54 4e-06
BC069387-1|AAH69387.1| 449|Homo sapiens VPS13C protein protein. 44 0.004
AK000143-1|BAA90972.1| 442|Homo sapiens protein ( Homo sapiens ... 44 0.004
AJ626861-1|CAF25188.1| 3628|Homo sapiens VPS13C-2B protein protein. 44 0.004
AJ626860-1|CAF25187.1| 3585|Homo sapiens VPS13C-1B protein protein. 44 0.004
AJ608771-1|CAE75583.1| 3753|Homo sapiens VPS13C-2A protein protein. 44 0.004
AJ608770-1|CAE75582.1| 3710|Homo sapiens VPS13C-1A protein protein. 44 0.004
AY223815-1|AAP41103.1| 3997|Homo sapiens Cohen syndrome 1 protei... 43 0.009
AY223814-1|AAP41102.1| 4022|Homo sapiens Cohen syndrome 1 protei... 43 0.009
AJ608773-1|CAE75585.1| 3997|Homo sapiens VPS13B-2A protein protein. 43 0.009
AJ608772-1|CAE75584.1| 4022|Homo sapiens VPS13B-1A protein protein. 43 0.009
AB011104-1|BAA25458.1| 1637|Homo sapiens KIAA0532 protein protein. 43 0.009
AK128650-1|BAC87549.1| 1662|Homo sapiens protein ( Homo sapiens ... 38 0.33
>BX784396-2|CAI19414.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 252 bits (617), Expect = 6e-66
Identities = 212/713 (29%), Positives = 308/713 (43%), Gaps = 96/713 (13%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 2755 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 2814
Query: 194 VRANWTADYYAPHAQVLRSVS----ASRIE--CQNERFLYVVCRTQSGAT-----EQSPK 242
+ +W ADY + + S S ++ C + V RT+S A+ Q
Sbjct: 2815 TKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYA 2874
Query: 243 SSPAGHRRRSPFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT- 293
+RR PFVP+ALRNHTG LWF TL TT + +G G+G DDT
Sbjct: 2875 REVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTH 2934
Query: 294 ----WMLVRAQHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFR 348
W V PF F L +R++GW+ PV VD+VG +FR
Sbjct: 2935 NVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR 2994
Query: 349 XXXXXXXXXXXXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGA 408
+ T+ SP +SR+ + P+V + +
Sbjct: 2995 -----YAAPDKNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLP 3027
Query: 409 EARIVFEVSLEGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPG 468
R+VF V++EGSARK++TVRSAL + N+L P+E+R+D +PS V + PG
Sbjct: 3028 PVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPG 3083
Query: 469 DSWAAPLEAEGGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPP 522
DS+A PL L IHW + S SK H S
Sbjct: 3084 DSFAVPLHLTSWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEK 3138
Query: 523 DHVYRFCCVMIRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSV 571
+RFC + +E +P D I GHT+ +
Sbjct: 3139 SRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF--- 3195
Query: 572 NKAGLVVHGSVAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXX 631
G+ ++G++ PG H + + +EL + LE F
Sbjct: 3196 YVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQN 3246
Query: 632 FSAKIKLRDTRSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAG 691
+ +++L D R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAG
Sbjct: 3247 YMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAG 3306
Query: 692 QFAEHELARVVAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLX 748
QF EHELAR ++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 3307 QFEEHELARSLSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL- 3364
Query: 749 XXXXXXXXXXXXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 3365 -KVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 3416
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 3991 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 4050
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 4051 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 4110
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 4111 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 4169
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 4170 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 4214
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 3874 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 3933
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 3934 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 3986
Query: 989 LKI 991
LKI
Sbjct: 3987 LKI 3989
>BX784395-2|CAI19412.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 252 bits (617), Expect = 6e-66
Identities = 212/713 (29%), Positives = 308/713 (43%), Gaps = 96/713 (13%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 2755 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 2814
Query: 194 VRANWTADYYAPHAQVLRSVS----ASRIE--CQNERFLYVVCRTQSGAT-----EQSPK 242
+ +W ADY + + S S ++ C + V RT+S A+ Q
Sbjct: 2815 TKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYA 2874
Query: 243 SSPAGHRRRSPFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT- 293
+RR PFVP+ALRNHTG LWF TL TT + +G G+G DDT
Sbjct: 2875 REVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTH 2934
Query: 294 ----WMLVRAQHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFR 348
W V PF F L +R++GW+ PV VD+VG +FR
Sbjct: 2935 NVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR 2994
Query: 349 XXXXXXXXXXXXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGA 408
+ T+ SP +SR+ + P+V + +
Sbjct: 2995 -----YAAPDKNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLP 3027
Query: 409 EARIVFEVSLEGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPG 468
R+VF V++EGSARK++TVRSAL + N+L P+E+R+D +PS V + PG
Sbjct: 3028 PVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPG 3083
Query: 469 DSWAAPLEAEGGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPP 522
DS+A PL L IHW + S SK H S
Sbjct: 3084 DSFAVPLHLTSWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEK 3138
Query: 523 DHVYRFCCVMIRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSV 571
+RFC + +E +P D I GHT+ +
Sbjct: 3139 SRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF--- 3195
Query: 572 NKAGLVVHGSVAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXX 631
G+ ++G++ PG H + + +EL + LE F
Sbjct: 3196 YVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQN 3246
Query: 632 FSAKIKLRDTRSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAG 691
+ +++L D R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAG
Sbjct: 3247 YMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAG 3306
Query: 692 QFAEHELARVVAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLX 748
QF EHELAR ++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 3307 QFEEHELARSLSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL- 3364
Query: 749 XXXXXXXXXXXXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 3365 -KVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 3416
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 3991 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 4050
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 4051 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 4110
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 4111 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 4169
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 4170 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 4214
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 3874 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 3933
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 3934 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 3986
Query: 989 LKI 991
LKI
Sbjct: 3987 LKI 3989
>BX682532-2|CAI23591.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 252 bits (617), Expect = 6e-66
Identities = 212/713 (29%), Positives = 308/713 (43%), Gaps = 96/713 (13%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 2755 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 2814
Query: 194 VRANWTADYYAPHAQVLRSVS----ASRIE--CQNERFLYVVCRTQSGAT-----EQSPK 242
+ +W ADY + + S S ++ C + V RT+S A+ Q
Sbjct: 2815 TKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYA 2874
Query: 243 SSPAGHRRRSPFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT- 293
+RR PFVP+ALRNHTG LWF TL TT + +G G+G DDT
Sbjct: 2875 REVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTH 2934
Query: 294 ----WMLVRAQHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFR 348
W V PF F L +R++GW+ PV VD+VG +FR
Sbjct: 2935 NVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR 2994
Query: 349 XXXXXXXXXXXXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGA 408
+ T+ SP +SR+ + P+V + +
Sbjct: 2995 -----YAAPDKNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLP 3027
Query: 409 EARIVFEVSLEGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPG 468
R+VF V++EGSARK++TVRSAL + N+L P+E+R+D +PS V + PG
Sbjct: 3028 PVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPG 3083
Query: 469 DSWAAPLEAEGGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPP 522
DS+A PL L IHW + S SK H S
Sbjct: 3084 DSFAVPLHLTSWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEK 3138
Query: 523 DHVYRFCCVMIRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSV 571
+RFC + +E +P D I GHT+ +
Sbjct: 3139 SRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF--- 3195
Query: 572 NKAGLVVHGSVAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXX 631
G+ ++G++ PG H + + +EL + LE F
Sbjct: 3196 YVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQN 3246
Query: 632 FSAKIKLRDTRSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAG 691
+ +++L D R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAG
Sbjct: 3247 YMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAG 3306
Query: 692 QFAEHELARVVAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLX 748
QF EHELAR ++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 3307 QFEEHELARSLSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL- 3364
Query: 749 XXXXXXXXXXXXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 3365 -KVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 3416
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 3991 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 4050
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 4051 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 4110
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 4111 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 4169
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 4170 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 4214
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 3874 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 3933
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 3934 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 3986
Query: 989 LKI 991
LKI
Sbjct: 3987 LKI 3989
>AL109757-2|CAI22116.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 252 bits (617), Expect = 6e-66
Identities = 212/713 (29%), Positives = 308/713 (43%), Gaps = 96/713 (13%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 2755 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 2814
Query: 194 VRANWTADYYAPHAQVLRSVS----ASRIE--CQNERFLYVVCRTQSGAT-----EQSPK 242
+ +W ADY + + S S ++ C + V RT+S A+ Q
Sbjct: 2815 TKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYA 2874
Query: 243 SSPAGHRRRSPFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT- 293
+RR PFVP+ALRNHTG LWF TL TT + +G G+G DDT
Sbjct: 2875 REVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTH 2934
Query: 294 ----WMLVRAQHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFR 348
W V PF F L +R++GW+ PV VD+VG +FR
Sbjct: 2935 NVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR 2994
Query: 349 XXXXXXXXXXXXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGA 408
+ T+ SP +SR+ + P+V + +
Sbjct: 2995 -----YAAPDKNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLP 3027
Query: 409 EARIVFEVSLEGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPG 468
R+VF V++EGSARK++TVRSAL + N+L P+E+R+D +PS V + PG
Sbjct: 3028 PVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPG 3083
Query: 469 DSWAAPLEAEGGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPP 522
DS+A PL L IHW + S SK H S
Sbjct: 3084 DSFAVPLHLTSWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEK 3138
Query: 523 DHVYRFCCVMIRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSV 571
+RFC + +E +P D I GHT+ +
Sbjct: 3139 SRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF--- 3195
Query: 572 NKAGLVVHGSVAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXX 631
G+ ++G++ PG H + + +EL + LE F
Sbjct: 3196 YVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQN 3246
Query: 632 FSAKIKLRDTRSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAG 691
+ +++L D R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAG
Sbjct: 3247 YMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAG 3306
Query: 692 QFAEHELARVVAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLX 748
QF EHELAR ++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 3307 QFEEHELARSLSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL- 3364
Query: 749 XXXXXXXXXXXXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 3365 -KVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 3416
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 3991 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 4050
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 4051 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 4110
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 4111 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 4169
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 4170 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 4214
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 3874 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 3933
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 3934 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 3986
Query: 989 LKI 991
LKI
Sbjct: 3987 LKI 3989
>AL031296-2|CAI23164.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 252 bits (617), Expect = 6e-66
Identities = 212/713 (29%), Positives = 308/713 (43%), Gaps = 96/713 (13%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 2755 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 2814
Query: 194 VRANWTADYYAPHAQVLRSVS----ASRIE--CQNERFLYVVCRTQSGAT-----EQSPK 242
+ +W ADY + + S S ++ C + V RT+S A+ Q
Sbjct: 2815 TKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYA 2874
Query: 243 SSPAGHRRRSPFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT- 293
+RR PFVP+ALRNHTG LWF TL TT + +G G+G DDT
Sbjct: 2875 REVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTH 2934
Query: 294 ----WMLVRAQHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFR 348
W V PF F L +R++GW+ PV VD+VG +FR
Sbjct: 2935 NVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR 2994
Query: 349 XXXXXXXXXXXXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGA 408
+ T+ SP +SR+ + P+V + +
Sbjct: 2995 -----YAAPDKNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLP 3027
Query: 409 EARIVFEVSLEGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPG 468
R+VF V++EGSARK++TVRSAL + N+L P+E+R+D +PS V + PG
Sbjct: 3028 PVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPG 3083
Query: 469 DSWAAPLEAEGGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPP 522
DS+A PL L IHW + S SK H S
Sbjct: 3084 DSFAVPLHLTSWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEK 3138
Query: 523 DHVYRFCCVMIRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSV 571
+RFC + +E +P D I GHT+ +
Sbjct: 3139 SRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF--- 3195
Query: 572 NKAGLVVHGSVAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXX 631
G+ ++G++ PG H + + +EL + LE F
Sbjct: 3196 YVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQN 3246
Query: 632 FSAKIKLRDTRSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAG 691
+ +++L D R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAG
Sbjct: 3247 YMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAG 3306
Query: 692 QFAEHELARVVAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLX 748
QF EHELAR ++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 3307 QFEEHELARSLSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL- 3364
Query: 749 XXXXXXXXXXXXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 3365 -KVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 3416
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 3991 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 4050
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 4051 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 4110
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 4111 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 4169
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 4170 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 4214
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 3874 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 3933
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 3934 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 3986
Query: 989 LKI 991
LKI
Sbjct: 3987 LKI 3989
>AL031276-2|CAI19223.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 252 bits (617), Expect = 6e-66
Identities = 212/713 (29%), Positives = 308/713 (43%), Gaps = 96/713 (13%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 2755 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 2814
Query: 194 VRANWTADYYAPHAQVLRSVS----ASRIE--CQNERFLYVVCRTQSGAT-----EQSPK 242
+ +W ADY + + S S ++ C + V RT+S A+ Q
Sbjct: 2815 TKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYA 2874
Query: 243 SSPAGHRRRSPFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT- 293
+RR PFVP+ALRNHTG LWF TL TT + +G G+G DDT
Sbjct: 2875 REVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTH 2934
Query: 294 ----WMLVRAQHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFR 348
W V PF F L +R++GW+ PV VD+VG +FR
Sbjct: 2935 NVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR 2994
Query: 349 XXXXXXXXXXXXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGA 408
+ T+ SP +SR+ + P+V + +
Sbjct: 2995 -----YAAPDKNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLP 3027
Query: 409 EARIVFEVSLEGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPG 468
R+VF V++EGSARK++TVRSAL + N+L P+E+R+D +PS V + PG
Sbjct: 3028 PVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPG 3083
Query: 469 DSWAAPLEAEGGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPP 522
DS+A PL L IHW + S SK H S
Sbjct: 3084 DSFAVPLHLTSWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEK 3138
Query: 523 DHVYRFCCVMIRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSV 571
+RFC + +E +P D I GHT+ +
Sbjct: 3139 SRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF--- 3195
Query: 572 NKAGLVVHGSVAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXX 631
G+ ++G++ PG H + + +EL + LE F
Sbjct: 3196 YVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQN 3246
Query: 632 FSAKIKLRDTRSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAG 691
+ +++L D R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAG
Sbjct: 3247 YMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAG 3306
Query: 692 QFAEHELARVVAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLX 748
QF EHELAR ++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 3307 QFEEHELARSLSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL- 3364
Query: 749 XXXXXXXXXXXXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 3365 -KVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 3416
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 3991 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 4050
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 4051 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 4110
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 4111 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 4169
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 4170 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 4214
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 3874 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 3933
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 3934 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 3986
Query: 989 LKI 991
LKI
Sbjct: 3987 LKI 3989
>AB007922-1|BAA32298.3| 3209|Homo sapiens KIAA0453 protein protein.
Length = 3209
Score = 252 bits (617), Expect = 6e-66
Identities = 212/713 (29%), Positives = 308/713 (43%), Gaps = 96/713 (13%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 1577 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 1636
Query: 194 VRANWTADYYAPHAQVLRSVS----ASRIE--CQNERFLYVVCRTQSGAT-----EQSPK 242
+ +W ADY + + S S ++ C + V RT+S A+ Q
Sbjct: 1637 TKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYA 1696
Query: 243 SSPAGHRRRSPFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT- 293
+RR PFVP+ALRNHTG LWF TL TT + +G G+G DDT
Sbjct: 1697 REVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTH 1756
Query: 294 ----WMLVRAQHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFR 348
W V PF F L +R++GW+ PV VD+VG +FR
Sbjct: 1757 NVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR 1816
Query: 349 XXXXXXXXXXXXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGA 408
+ T+ SP +SR+ + P+V + +
Sbjct: 1817 -----YAAPDKNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLP 1849
Query: 409 EARIVFEVSLEGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPG 468
R+VF V++EGSARK++TVRSAL + N+L P+E+R+D +PS V + PG
Sbjct: 1850 PVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPG 1905
Query: 469 DSWAAPLEAEGGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPP 522
DS+A PL L IHW + S SK H S
Sbjct: 1906 DSFAVPLHLTSWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEK 1960
Query: 523 DHVYRFCCVMIRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSV 571
+RFC + +E +P D I GHT+ +
Sbjct: 1961 SRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF--- 2017
Query: 572 NKAGLVVHGSVAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXX 631
G+ ++G++ PG H + + +EL + LE F
Sbjct: 2018 YVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQN 2068
Query: 632 FSAKIKLRDTRSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAG 691
+ +++L D R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAG
Sbjct: 2069 YMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAG 2128
Query: 692 QFAEHELARVVAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLX 748
QF EHELAR ++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 2129 QFEEHELARSLSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL- 2186
Query: 749 XXXXXXXXXXXXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 2187 -KVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 2238
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 2813 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 2872
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 2873 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 2932
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 2933 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 2991
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 2992 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 3036
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 2696 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 2755
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 2756 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 2808
Query: 989 LKI 991
LKI
Sbjct: 2809 LKI 2811
>AJ608774-1|CAE75586.1| 4388|Homo sapiens VPS13D-1A protein protein.
Length = 4388
Score = 251 bits (615), Expect = 1e-65
Identities = 211/714 (29%), Positives = 310/714 (43%), Gaps = 97/714 (13%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 2755 DYYNRALSGWEPFIEPWPCSVSWQQQAAGRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 2814
Query: 194 VRANWTADYYAPHAQVLRSVS----ASRIE--CQNERFLYVVCRTQSGATEQS------P 241
+ +W ADY + + S S ++ C + V RT+S A+ +
Sbjct: 2815 TKESWMADYCKDDKDIESAKSEDWMGSSVDPPCFGQSLPLVYLRTRSTASLTNLEHQIYA 2874
Query: 242 KSSPAGHRRRSPFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT 293
++ +RR PFVP+ALRNHTG LWF TL TT + +G G+G DDT
Sbjct: 2875 RAEVKTPKRRQPFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDT 2934
Query: 294 -----WMLVRAQHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYF 347
W V PF F L +R++GW+ PV VD+VG +F
Sbjct: 2935 HNVSEWREVLTGEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFF 2994
Query: 348 RXXXXXXXXXXXXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTG 407
R + T+ SP +SR+ + P+V + +
Sbjct: 2995 R-----YAAPDKNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSL 3027
Query: 408 AEARIVFEVSLEGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSP 467
R+VF V++EGSARK++TVRSAL + N+L P+E+R+D +PS V + P
Sbjct: 3028 PPVRVVFAVTMEGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMP 3083
Query: 468 GDSWAAPLEAEGGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAP 521
GDS+A PL L IHW + S SK H S
Sbjct: 3084 GDSFAVPLHLTSWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTE 3138
Query: 522 PDHVYRFCCVMIRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRS 570
+RFC + +E +P D I GHT+ +
Sbjct: 3139 KSRFFRFCVAIKKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF-- 3196
Query: 571 VNKAGLVVHGSVAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXX 630
G+ ++G++ PG H + + +EL + LE F
Sbjct: 3197 -YVKGMPINGTLKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQ 3246
Query: 631 XFSAKIKLRDTRSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAA 690
+ +++L D R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAA
Sbjct: 3247 NYMVRMRLYDVNRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAA 3306
Query: 691 GQFAEHELARVVAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRL 747
GQF EHELAR ++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 3307 GQFEEHELARSLSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL 3365
Query: 748 XXXXXXXXXXXXXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 3366 --KVIQQGNRPGLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 3417
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 3992 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 4051
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 4052 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 4111
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 4112 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 4170
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 4171 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 4215
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 3875 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 3934
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 3935 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 3987
Query: 989 LKI 991
LKI
Sbjct: 3988 LKI 3990
>BX784396-1|CAI19413.1| 2270|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 2270
Score = 247 bits (605), Expect = 2e-64
Identities = 210/703 (29%), Positives = 306/703 (43%), Gaps = 100/703 (14%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 662 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 721
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 722 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 767
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 768 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 827
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 828 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 882
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 883 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 920
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAE 478
EGSARK++TVRSAL + N+L P+E+R+D +PS V + PGDS+A PL
Sbjct: 921 EGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLT 976
Query: 479 GGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPPDHVYRFCCVM 532
L IHW + S SK H S +RFC +
Sbjct: 977 SWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAI 1031
Query: 533 IRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGS 581
+E +P D I GHT+ + G+ ++G+
Sbjct: 1032 KKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF---YVKGMPINGT 1088
Query: 582 VAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDT 641
+ PG H + + +EL + LE F + +++L D
Sbjct: 1089 LKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQNYMVRMRLYDV 1139
Query: 642 RSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARV 701
R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAGQF EHELAR
Sbjct: 1140 NRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARS 1199
Query: 702 VAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXX 758
++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 1200 LSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRP 1256
Query: 759 XXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 1257 GLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 1299
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 1874 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 1933
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 1934 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 1993
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 1994 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 2052
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 2053 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 2097
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 1757 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 1816
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 1817 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 1869
Query: 989 LKI 991
LKI
Sbjct: 1870 LKI 1872
>BX784395-1|CAI19411.1| 2270|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 2270
Score = 247 bits (605), Expect = 2e-64
Identities = 210/703 (29%), Positives = 306/703 (43%), Gaps = 100/703 (14%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 662 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 721
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 722 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 767
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 768 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 827
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 828 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 882
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 883 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 920
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAE 478
EGSARK++TVRSAL + N+L P+E+R+D +PS V + PGDS+A PL
Sbjct: 921 EGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLT 976
Query: 479 GGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPPDHVYRFCCVM 532
L IHW + S SK H S +RFC +
Sbjct: 977 SWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAI 1031
Query: 533 IRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGS 581
+E +P D I GHT+ + G+ ++G+
Sbjct: 1032 KKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF---YVKGMPINGT 1088
Query: 582 VAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDT 641
+ PG H + + +EL + LE F + +++L D
Sbjct: 1089 LKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQNYMVRMRLYDV 1139
Query: 642 RSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARV 701
R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAGQF EHELAR
Sbjct: 1140 NRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARS 1199
Query: 702 VAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXX 758
++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 1200 LSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRP 1256
Query: 759 XXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 1257 GLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 1299
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 1874 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 1933
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 1934 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 1993
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 1994 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 2052
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 2053 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 2097
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 1757 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 1816
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 1817 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 1869
Query: 989 LKI 991
LKI
Sbjct: 1870 LKI 1872
>BX682532-1|CAI23590.1| 2270|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 2270
Score = 247 bits (605), Expect = 2e-64
Identities = 210/703 (29%), Positives = 306/703 (43%), Gaps = 100/703 (14%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 662 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 721
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 722 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 767
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 768 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 827
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 828 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 882
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 883 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 920
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAE 478
EGSARK++TVRSAL + N+L P+E+R+D +PS V + PGDS+A PL
Sbjct: 921 EGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLT 976
Query: 479 GGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPPDHVYRFCCVM 532
L IHW + S SK H S +RFC +
Sbjct: 977 SWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAI 1031
Query: 533 IRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGS 581
+E +P D I GHT+ + G+ ++G+
Sbjct: 1032 KKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF---YVKGMPINGT 1088
Query: 582 VAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDT 641
+ PG H + + +EL + LE F + +++L D
Sbjct: 1089 LKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQNYMVRMRLYDV 1139
Query: 642 RSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARV 701
R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAGQF EHELAR
Sbjct: 1140 NRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARS 1199
Query: 702 VAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXX 758
++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 1200 LSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRP 1256
Query: 759 XXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 1257 GLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 1299
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 1874 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 1933
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 1934 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 1993
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 1994 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 2052
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 2053 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 2097
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 1757 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 1816
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 1817 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 1869
Query: 989 LKI 991
LKI
Sbjct: 1870 LKI 1872
>AL109757-1|CAI22115.1| 2270|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 2270
Score = 247 bits (605), Expect = 2e-64
Identities = 210/703 (29%), Positives = 306/703 (43%), Gaps = 100/703 (14%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 662 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 721
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 722 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 767
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 768 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 827
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 828 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 882
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 883 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 920
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAE 478
EGSARK++TVRSAL + N+L P+E+R+D +PS V + PGDS+A PL
Sbjct: 921 EGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLT 976
Query: 479 GGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPPDHVYRFCCVM 532
L IHW + S SK H S +RFC +
Sbjct: 977 SWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAI 1031
Query: 533 IRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGS 581
+E +P D I GHT+ + G+ ++G+
Sbjct: 1032 KKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF---YVKGMPINGT 1088
Query: 582 VAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDT 641
+ PG H + + +EL + LE F + +++L D
Sbjct: 1089 LKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQNYMVRMRLYDV 1139
Query: 642 RSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARV 701
R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAGQF EHELAR
Sbjct: 1140 NRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARS 1199
Query: 702 VAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXX 758
++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 1200 LSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRP 1256
Query: 759 XXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 1257 GLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 1299
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 1874 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 1933
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 1934 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 1993
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 1994 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 2052
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 2053 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 2097
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 1757 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 1816
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 1817 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 1869
Query: 989 LKI 991
LKI
Sbjct: 1870 LKI 1872
>AL031296-1|CAI23163.1| 2270|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 2270
Score = 247 bits (605), Expect = 2e-64
Identities = 210/703 (29%), Positives = 306/703 (43%), Gaps = 100/703 (14%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 662 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 721
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 722 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 767
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 768 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 827
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 828 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 882
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 883 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 920
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAE 478
EGSARK++TVRSAL + N+L P+E+R+D +PS V + PGDS+A PL
Sbjct: 921 EGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLT 976
Query: 479 GGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPPDHVYRFCCVM 532
L IHW + S SK H S +RFC +
Sbjct: 977 SWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAI 1031
Query: 533 IRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGS 581
+E +P D I GHT+ + G+ ++G+
Sbjct: 1032 KKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF---YVKGMPINGT 1088
Query: 582 VAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDT 641
+ PG H + + +EL + LE F + +++L D
Sbjct: 1089 LKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQNYMVRMRLYDV 1139
Query: 642 RSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARV 701
R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAGQF EHELAR
Sbjct: 1140 NRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARS 1199
Query: 702 VAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXX 758
++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 1200 LSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRP 1256
Query: 759 XXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 1257 GLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 1299
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 1874 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 1933
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 1934 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 1993
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 1994 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 2052
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 2053 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 2097
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 1757 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 1816
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 1817 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 1869
Query: 989 LKI 991
LKI
Sbjct: 1870 LKI 1872
>AL031276-1|CAI19222.1| 2270|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 2270
Score = 247 bits (605), Expect = 2e-64
Identities = 210/703 (29%), Positives = 306/703 (43%), Gaps = 100/703 (14%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 662 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 721
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 722 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 767
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 768 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 827
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 828 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 882
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 883 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 920
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAE 478
EGSARK++TVRSAL + N+L P+E+R+D +PS V + PGDS+A PL
Sbjct: 921 EGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLT 976
Query: 479 GGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPPDHVYRFCCVM 532
L IHW + S SK H S +RFC +
Sbjct: 977 SWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAI 1031
Query: 533 IRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGS 581
+E +P D I GHT+ + G+ ++G+
Sbjct: 1032 KKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF---YVKGMPINGT 1088
Query: 582 VAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDT 641
+ PG H + + +EL + LE F + +++L D
Sbjct: 1089 LKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQNYMVRMRLYDV 1139
Query: 642 RSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARV 701
R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAGQF EHELAR
Sbjct: 1140 NRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARS 1199
Query: 702 VAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXX 758
++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 1200 LSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRP 1256
Query: 759 XXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 1257 GLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 1299
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 1874 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 1933
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 1934 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 1993
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 1994 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 2052
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 2053 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 2097
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 1757 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 1816
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 1817 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 1869
Query: 989 LKI 991
LKI
Sbjct: 1870 LKI 1872
>AJ608775-1|CAE75587.1| 4363|Homo sapiens VPS13D-2A protein protein.
Length = 4363
Score = 247 bits (604), Expect = 2e-64
Identities = 210/703 (29%), Positives = 306/703 (43%), Gaps = 100/703 (14%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 2755 DYYNRALSGWEPFIEPWPCSVSWQQQAAGRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 2814
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 2815 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 2860
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 2861 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 2920
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 2921 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 2975
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 2976 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 3013
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAE 478
EGSARK++TVRSAL + N+L P+E+R+D +PS V + PGDS+A PL
Sbjct: 3014 EGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLT 3069
Query: 479 GGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPPDHVYRFCCVM 532
L IHW + S SK H S +RFC +
Sbjct: 3070 SWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAI 3124
Query: 533 IRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGS 581
+E +P D I GHT+ + G+ ++G+
Sbjct: 3125 KKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF---YVKGMPINGT 3181
Query: 582 VAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDT 641
+ PG H + + +EL + LE F + +++L D
Sbjct: 3182 LKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQNYMVRMRLYDV 3232
Query: 642 RSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARV 701
R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAGQF EHELAR
Sbjct: 3233 NRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARS 3292
Query: 702 VAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXX 758
++PLLF +A+ + +P LC R+GRG+ G P WC F L G V+ L
Sbjct: 3293 LSPLLFCYADKE-QPNLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRP 3349
Query: 759 XXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V APRY L N ++ L FAQ
Sbjct: 3350 GLIYNIGIDVKKGRGRYIDTCMVIFAPRYLLDNKSSHKLAFAQ 3392
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 3967 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 4026
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 4027 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 4086
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 4087 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 4145
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 4146 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 4190
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 3850 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 3909
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 3910 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 3962
Query: 989 LKI 991
LKI
Sbjct: 3963 LKI 3965
>BX641035-1|CAE46021.1| 1571|Homo sapiens hypothetical protein
protein.
Length = 1571
Score = 246 bits (603), Expect = 3e-64
Identities = 209/703 (29%), Positives = 306/703 (43%), Gaps = 100/703 (14%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 662 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 721
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 722 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 767
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 768 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 827
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 828 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 882
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 883 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 920
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAE 478
EGSARK++TVRSAL + N+L P+E+R+D +PS V + PGDS+A PL
Sbjct: 921 EGSARKVITVRSALIVRNRLETPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLT 976
Query: 479 GGALWXXXXXXXXXXXXXXXXXXIHW------KDASPSKPLLHYSCTAPPDHVYRFCCVM 532
L IHW + S SK H S +RFC +
Sbjct: 977 SWRL----QARPKGLGVFFCKAPIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAI 1031
Query: 533 IRERFP--------PDRGPPI---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGS 581
+E +P D I GHT+ + G+ ++G+
Sbjct: 1032 KKENYPDYMPSNIFSDSAKQIFRQPGHTIYLLPTVVICNLLPCELDF---YVKGMPINGT 1088
Query: 582 VAPGDTKPFHQVNVEEGVELSIKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDT 641
+ PG H + + +EL + LE F + +++L D
Sbjct: 1089 LKPGKEAALHTADTSQNIELGVSLENF---------PLCKELLIPPGTQNYMVRMRLYDV 1139
Query: 642 RSRRLYLNARVTVKKTDGMKVSVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARV 701
R+L L R+ + +K+ +SA YWL+N+TGLPL++R + + DAAGQF EHELAR
Sbjct: 1140 NRRQLNLTIRIVCRAEGSLKIFISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARS 1199
Query: 702 VAPLLFSFAEPDARPTLCA-RLGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXX 758
++PLLF +A+ + +P+LC R+GRG+ G P WC F L G V+ L
Sbjct: 1200 LSPLLFCYADKE-QPSLCTMRIGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRP 1256
Query: 759 XXXXXXXXSVRAGRGRYRRTNIVTLAPRYQLHNNTTRTLQFAQ 801
V+ GRGRY T +V PRY L N ++ L FAQ
Sbjct: 1257 GLIYSIGIDVKKGRGRYIDTCMVIFTPRYLLDNKSSHKLAFAQ 1299
>BC028115-1|AAH28115.1| 1412|Homo sapiens VPS13D protein protein.
Length = 1412
Score = 180 bits (439), Expect = 2e-44
Identities = 138/442 (31%), Positives = 203/442 (45%), Gaps = 47/442 (10%)
Query: 380 TTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSLEGSARKLVTVRSALQLVNKLP 439
++S T S +SR+ + P+V + + R+VF V++EGSARK++TVRSAL + N+L
Sbjct: 27 SSSSTIGSPSSRTNIIHPQV---YFSSLPPVRVVFAVTMEGSARKVITVRSALIVRNRLE 83
Query: 440 HPVEVRMDHAPSTAQWVGGGVRSARVSPGDSWAAPLEAEGGALWXXXXXXXXXXXXXXXX 499
P+E+R+D +PS V + PGDS+A PL L
Sbjct: 84 TPMELRLD-SPSAPD---KPVVLPAIMPGDSFAVPLHLTSWRL----QARPKGLGVFFCK 135
Query: 500 XXIHWKDA------SPSKPLLHYSCTAPPDHVYRFCCVMIRERFPP--------DRGPPI 545
IHW + S SK H S +RFC + +E +P D I
Sbjct: 136 APIHWTNVVKTAEISSSKRECH-SMDTEKSRFFRFCVAIKKENYPDYMPSNIFSDSAKQI 194
Query: 546 ---AGHTLTXXXXXXXXXXXXXXXQYRSVNKAGLVVHGSVAPGDTKPFHQVNVEEGVELS 602
GHT+ + G+ +G++ PG H + + +EL
Sbjct: 195 FRQPGHTIYLLPTVVICNLLPCELDFYV---KGMPTNGTLKPGKEAALHTADTSQNIELG 251
Query: 603 IKLEGFGWXXXXXXXXXXXXXXXXXXXXXFSAKIKLRDTRSRRLYLNARVTVKKTDGMKV 662
+ LE F + +++L D R+L L R+ + +K+
Sbjct: 252 VSLENFP---------LCKELLIPPGTQNYMVRMRLYDVNRRQLNLTIRIVCRAEGSLKI 302
Query: 663 SVSAAYWLVNRTGLPLVYRAEGSAADAAGQFAEHELARVVAPLLFSFAEPDARPTLCA-R 721
+SA YWL+N+TGLPL++R + + DAAGQF EHELAR ++PLLF +A+ + +P LC R
Sbjct: 303 FISAPYWLINKTGLPLIFRQDNAKTDAAGQFEEHELARSLSPLLFCYADKE-QPNLCTMR 361
Query: 722 LGRGL--PGNPEWCSPFGLGPGVSVKRLXXXXXXXXXXXXXXXXXXXSVRAGRGRYRRTN 779
+GRG+ G P WC F L G V+ L V+ GRGRY T
Sbjct: 362 IGRGIHPEGMPGWCQGFSLDGGSGVRAL--KVIQQGNRPGLIYNIGIDVKKGRGRYIDTC 419
Query: 780 IVTLAPRYQLHNNTTRTLQFAQ 801
+V APRY L N ++ L FAQ
Sbjct: 420 MVIFAPRYLLDNKSSHKLAFAQ 441
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 1016 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 1075
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 1076 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 1135
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 1136 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 1194
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 1195 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 1239
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 899 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 958
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 959 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 1011
Query: 989 LKI 991
LKI
Sbjct: 1012 LKI 1014
>BC051804-1|AAH51804.1| 908|Homo sapiens VPS13D protein protein.
Length = 908
Score = 166 bits (403), Expect = 5e-40
Identities = 91/225 (40%), Positives = 125/225 (55%), Gaps = 4/225 (1%)
Query: 1026 LAQIRLSMCTANXXXXXXXXXXXXXXXXXIKFEDAAVELEPFERVHVFETASYLGRQMLA 1085
+ QI+LS+ T+N I+FEDA + L+PF RVH +ET ++ +L
Sbjct: 512 IPQIKLSVFTSNKLPLDLKALKSTLGFPLIRFEDAVINLDPFTRVHPYETKEFIINDILK 571
Query: 1086 HFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVTGLLLEGNVGALLKNVTHGISNSAAK 1145
HF++EL QAA+ILGSVDFLGNP+G + DVSEGVTGL+ GNVG L++NVTHG+SNSAAK
Sbjct: 572 HFQEELLSQAARILGSVDFLGNPMGLLNDVSEGVTGLIKYGNVGGLIRNVTHGVSNSAAK 631
Query: 1146 VSESLGDGLERVVWDEAHEETRRRIR--SXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYE 1203
+ +L DGL + + D H+ R IR + +TS++ + E
Sbjct: 632 FAGTLSDGLGKTM-DNRHQSEREYIRYHAATSGEHLVAGIHGLAHGIIGGLTSVITSTVE 690
Query: 1204 GA-TQEXXXXXXXXXXXXXXXXXXXPVIGVLDLAAETASALRDTS 1247
G T+ PV G LD A+ETA A+RDT+
Sbjct: 691 GVKTEGGVSGFISGLGKGLVGTVTKPVAGALDFASETAQAVRDTA 735
Score = 56.8 bits (131), Expect = 5e-07
Identities = 40/123 (32%), Positives = 63/123 (51%), Gaps = 12/123 (9%)
Query: 874 QDMQWDNQLLGTPSPVLLYCLPDRSGANAPALHASVELQ--RSPSDKYNAYFFRHLVVAL 931
QD+Q DNQL+GT P +LY P + +V++ + PS ++HL++
Sbjct: 395 QDVQVDNQLIGTTQPFMLYVTPLSNENEVIETGPAVQVNAVKFPSKSALTNIYKHLMITA 454
Query: 932 KPLAVRLEERLILVLWSWWREEDEDSAQEQVDEADYETRRMLHSLTAL---SATRYYFGL 988
+ V++EE+L+L L S++ + +S E+ DE LH TA + RYYF
Sbjct: 455 QRFTVQIEEKLLLKLLSFFGYDQAESEVEKYDE-------NLHEKTAEQGGTPIRYYFEN 507
Query: 989 LKI 991
LKI
Sbjct: 508 LKI 510
>AK125118-1|BAC86054.1| 944|Homo sapiens protein ( Homo sapiens
cDNA FLJ43128 fis, clone CTONG3005325. ).
Length = 944
Score = 119 bits (287), Expect = 6e-26
Identities = 103/333 (30%), Positives = 152/333 (45%), Gaps = 57/333 (17%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 648 DYYNRALSGWEPFIEPWPCSVSWQQQAASRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 707
Query: 194 VRANWTADYYAPHAQVLRSVSASRIECQNERFLYVVCRTQSGATE-QSPKSSPAGHRRRS 252
+ +W ADY + + +++ E + C G TE ++PK RR
Sbjct: 708 TKESWMADYCKDD----KDIESAKSEDWMGSSVDPPC---FGQTEVKTPK-------RRQ 753
Query: 253 PFVPYALRNHTGHKLWFTTLLTTVDE--MRPTG------RGDGCGPDDT-----WMLVRA 299
PFVP+ALRNHTG LWF TL TT + +G G+G DDT W V
Sbjct: 754 PFVPFALRNHTGCTLWFATLTTTPTRAALSHSGSPGVVPEGNGTFLDDTHNVSEWREVLT 813
Query: 300 QHTEPFSFGGXXXXXXXXXXXXXWTVL-LRLDGWDPPDPVCVDRVGLYFRXXXXXXXXXX 358
PF F L +R++GW+ PV VD+VG +FR
Sbjct: 814 GEEIPFEFEARGKLRHRHTHDLRIHQLQVRVNGWEQVSPVSVDKVGTFFR-----YAAPD 868
Query: 359 XXXXNDTLARLVSETFRCGPCTTSPTTMSLASRSAFLPPEVQPLFQKTGAEARIVFEVSL 418
+ T+ SP +SR+ + P+V + + R+VF V++
Sbjct: 869 KNSSSSTIG--------------SP-----SSRTNIIHPQV---YFSSLPPVRVVFAVTM 906
Query: 419 EGSARKLVTVRSALQLVNKLPHPVEVRMDHAPS 451
EGSARK++TVRSAL + N+L P+E+R+D +PS
Sbjct: 907 EGSARKVITVRSALIVRNRLETPMELRLD-SPS 938
>AK001481-1|BAA91716.1| 609|Homo sapiens protein ( Homo sapiens
cDNA FLJ10619 fis, clone NT2RP2005472. ).
Length = 609
Score = 54.8 bits (126), Expect = 2e-06
Identities = 22/69 (31%), Positives = 34/69 (49%)
Query: 134 DYYNRTLSSWEPMVEPWRFXXXXXXXXXXXXXXXXAQVHVTSAETLNLNVTSALVELLML 193
DYYNR LS WEP +EPW ++ + L++N+TS L++ +
Sbjct: 493 DYYNRALSGWEPFIEPWPCSVSWQQQAAGRLHPPRLKLEAKAKPRLDINITSVLIDQYVS 552
Query: 194 VRANWTADY 202
+ +W ADY
Sbjct: 553 TKESWMADY 561
>BC041852-1|AAH41852.1| 1246|Homo sapiens VPS13A protein protein.
Length = 1246
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 970 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 1028
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 1029 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 1088
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 1089 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 1148
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 1149 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 1197
>AL359204-2|CAI39538.1| 3174|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3174
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AL359204-1|CAI39537.1| 3095|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3095
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AL353710-2|CAH74106.1| 3174|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3174
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AL353710-1|CAH74105.1| 3095|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3095
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AL158159-2|CAI40936.1| 3174|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3174
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AL158159-1|CAI40935.1| 3095|Homo sapiens vacuolar protein sorting 13
homolog A (S. cerevisiae) protein.
Length = 3095
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AK022967-1|BAB14337.1| 975|Homo sapiens protein ( Homo sapiens cDNA
FLJ12905 fis, clone NT2RP2004366, weakly similar to
VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13. ).
Length = 975
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 620 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 678
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 679 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 738
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 739 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 798
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 799 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 847
>AJ626859-1|CAF25186.1| 3069|Homo sapiens chorein 1D protein.
Length = 3069
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AJ608769-1|CAE75581.1| 3135|Homo sapiens chorein 2A protein.
Length = 3135
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2780 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2838
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2839 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2898
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2899 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2958
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2959 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3007
>AF337532-1|AAK61861.1| 3174|Homo sapiens chorea-acanthocytosis
protein.
Length = 3174
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AB054005-1|BAB59128.1| 3095|Homo sapiens chorein protein.
Length = 3095
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 2819 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 2877
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 2878 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 2937
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 2938 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 2997
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 2998 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 3046
>AB023203-1|BAA76830.1| 1458|Homo sapiens KIAA0986 protein protein.
Length = 1458
Score = 54.0 bits (124), Expect = 4e-06
Identities = 51/229 (22%), Positives = 87/229 (37%), Gaps = 23/229 (10%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHF-KDELKWQAAKILGSVDFLGNPLGFVADVS 1116
+D +L FE + F T S L +++ H+ K +K ILG +D LGNP G + + S
Sbjct: 1182 QDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILG-LDVLGNPFGLIREFS 1240
Query: 1117 EGVTGLLLEGNVG-----------------ALLKNVTHGISNSAAKVSESLGDGLERVVW 1159
EGV E G AL+ G++ +A+K++ ++ G+ +
Sbjct: 1241 EGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTM 1300
Query: 1160 DEAHEETRRRI---RSXXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXX 1216
DE +++ RR + +T +V +GA +
Sbjct: 1301 DEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKG 1360
Query: 1217 XXXXXXXXXXXPVIGVLDLAAETASAL-RDTSRRYVRLPAPPLVYTRHG 1264
P G++D+A+ T + R T V PP + G
Sbjct: 1361 VGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDG 1409
>BC069387-1|AAH69387.1| 449|Homo sapiens VPS13C protein protein.
Length = 449
Score = 44.0 bits (99), Expect = 0.004
Identities = 41/207 (19%), Positives = 77/207 (37%), Gaps = 20/207 (9%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSE 1117
+D +L +E + F L ++ H+ ++ Q ++ +D LGNP G + +SE
Sbjct: 72 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 131
Query: 1118 GVTGLLLEGNVGA-----------------LLKNVTHGISNSAAKVSESLGDGLERVVWD 1160
GV L E GA L + G + ++++ S+G GL + D
Sbjct: 132 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 191
Query: 1161 EAHEETRRRIRS---XXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXXX 1217
+ +++ RR S +T ++ EGA +E
Sbjct: 192 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 251
Query: 1218 XXXXXXXXXXPVIGVLDLAAETASALR 1244
P G++D+A+ T ++
Sbjct: 252 GKGLVGAVARPTGGIVDMASSTFQGIQ 278
>AK000143-1|BAA90972.1| 442|Homo sapiens protein ( Homo sapiens cDNA
FLJ20136 fis, clone COL07068. ).
Length = 442
Score = 44.0 bits (99), Expect = 0.004
Identities = 41/207 (19%), Positives = 77/207 (37%), Gaps = 20/207 (9%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSE 1117
+D +L +E + F L ++ H+ ++ Q ++ +D LGNP G + +SE
Sbjct: 65 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 124
Query: 1118 GVTGLLLEGNVGA-----------------LLKNVTHGISNSAAKVSESLGDGLERVVWD 1160
GV L E GA L + G + ++++ S+G GL + D
Sbjct: 125 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 184
Query: 1161 EAHEETRRRIRS---XXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXXX 1217
+ +++ RR S +T ++ EGA +E
Sbjct: 185 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 244
Query: 1218 XXXXXXXXXXPVIGVLDLAAETASALR 1244
P G++D+A+ T ++
Sbjct: 245 GKGLVGAVARPTGGIVDMASSTFQGIQ 271
>AJ626861-1|CAF25188.1| 3628|Homo sapiens VPS13C-2B protein protein.
Length = 3628
Score = 44.0 bits (99), Expect = 0.004
Identities = 41/207 (19%), Positives = 77/207 (37%), Gaps = 20/207 (9%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSE 1117
+D +L +E + F L ++ H+ ++ Q ++ +D LGNP G + +SE
Sbjct: 3376 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 3435
Query: 1118 GVTGLLLEGNVGA-----------------LLKNVTHGISNSAAKVSESLGDGLERVVWD 1160
GV L E GA L + G + ++++ S+G GL + D
Sbjct: 3436 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 3495
Query: 1161 EAHEETRRRIRS---XXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXXX 1217
+ +++ RR S +T ++ EGA +E
Sbjct: 3496 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 3555
Query: 1218 XXXXXXXXXXPVIGVLDLAAETASALR 1244
P G++D+A+ T ++
Sbjct: 3556 GKGLVGAVARPTGGIVDMASSTFQGIQ 3582
>AJ626860-1|CAF25187.1| 3585|Homo sapiens VPS13C-1B protein protein.
Length = 3585
Score = 44.0 bits (99), Expect = 0.004
Identities = 41/207 (19%), Positives = 77/207 (37%), Gaps = 20/207 (9%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSE 1117
+D +L +E + F L ++ H+ ++ Q ++ +D LGNP G + +SE
Sbjct: 3333 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 3392
Query: 1118 GVTGLLLEGNVGA-----------------LLKNVTHGISNSAAKVSESLGDGLERVVWD 1160
GV L E GA L + G + ++++ S+G GL + D
Sbjct: 3393 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 3452
Query: 1161 EAHEETRRRIRS---XXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXXX 1217
+ +++ RR S +T ++ EGA +E
Sbjct: 3453 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 3512
Query: 1218 XXXXXXXXXXPVIGVLDLAAETASALR 1244
P G++D+A+ T ++
Sbjct: 3513 GKGLVGAVARPTGGIVDMASSTFQGIQ 3539
>AJ608771-1|CAE75583.1| 3753|Homo sapiens VPS13C-2A protein protein.
Length = 3753
Score = 44.0 bits (99), Expect = 0.004
Identities = 41/207 (19%), Positives = 77/207 (37%), Gaps = 20/207 (9%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSE 1117
+D +L +E + F L ++ H+ ++ Q ++ +D LGNP G + +SE
Sbjct: 3376 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 3435
Query: 1118 GVTGLLLEGNVGA-----------------LLKNVTHGISNSAAKVSESLGDGLERVVWD 1160
GV L E GA L + G + ++++ S+G GL + D
Sbjct: 3436 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 3495
Query: 1161 EAHEETRRRIRS---XXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXXX 1217
+ +++ RR S +T ++ EGA +E
Sbjct: 3496 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 3555
Query: 1218 XXXXXXXXXXPVIGVLDLAAETASALR 1244
P G++D+A+ T ++
Sbjct: 3556 GKGLVGAVARPTGGIVDMASSTFQGIQ 3582
>AJ608770-1|CAE75582.1| 3710|Homo sapiens VPS13C-1A protein protein.
Length = 3710
Score = 44.0 bits (99), Expect = 0.004
Identities = 41/207 (19%), Positives = 77/207 (37%), Gaps = 20/207 (9%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSE 1117
+D +L +E + F L ++ H+ ++ Q ++ +D LGNP G + +SE
Sbjct: 3333 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 3392
Query: 1118 GVTGLLLEGNVGA-----------------LLKNVTHGISNSAAKVSESLGDGLERVVWD 1160
GV L E GA L + G + ++++ S+G GL + D
Sbjct: 3393 GVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMD 3452
Query: 1161 EAHEETRRRIRS---XXXXXXXXXXXXXXXXXXXXXMTSLVKHSYEGATQEXXXXXXXXX 1217
+ +++ RR S +T ++ EGA +E
Sbjct: 3453 KEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGI 3512
Query: 1218 XXXXXXXXXXPVIGVLDLAAETASALR 1244
P G++D+A+ T ++
Sbjct: 3513 GKGLVGAVARPTGGIVDMASSTFQGIQ 3539
>AY223815-1|AAP41103.1| 3997|Homo sapiens Cohen syndrome 1 protein
splice variant 1 protein.
Length = 3997
Score = 42.7 bits (96), Expect = 0.009
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 21/125 (16%)
Query: 1067 FERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVT------ 1120
FER +F TA L + H+ ++A ++GS+D LG+P V + GV
Sbjct: 3594 FERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLP 3653
Query: 1121 --------GLLLEG---NVGALLKNVTHGISNSAAKVSESLGDGLERVVWDEAH----EE 1165
G + G + +K+++ G S ++ SL ++R+ DE H EE
Sbjct: 3654 YEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEE 3713
Query: 1166 TRRRI 1170
RR++
Sbjct: 3714 WRRQL 3718
>AY223814-1|AAP41102.1| 4022|Homo sapiens Cohen syndrome 1 protein
protein.
Length = 4022
Score = 42.7 bits (96), Expect = 0.009
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 21/125 (16%)
Query: 1067 FERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVT------ 1120
FER +F TA L + H+ ++A ++GS+D LG+P V + GV
Sbjct: 3619 FERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLP 3678
Query: 1121 --------GLLLEG---NVGALLKNVTHGISNSAAKVSESLGDGLERVVWDEAH----EE 1165
G + G + +K+++ G S ++ SL ++R+ DE H EE
Sbjct: 3679 YEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEE 3738
Query: 1166 TRRRI 1170
RR++
Sbjct: 3739 WRRQL 3743
>AJ608773-1|CAE75585.1| 3997|Homo sapiens VPS13B-2A protein protein.
Length = 3997
Score = 42.7 bits (96), Expect = 0.009
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 21/125 (16%)
Query: 1067 FERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVT------ 1120
FER +F TA L + H+ ++A ++GS+D LG+P V + GV
Sbjct: 3594 FERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLP 3653
Query: 1121 --------GLLLEG---NVGALLKNVTHGISNSAAKVSESLGDGLERVVWDEAH----EE 1165
G + G + +K+++ G S ++ SL ++R+ DE H EE
Sbjct: 3654 YEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEE 3713
Query: 1166 TRRRI 1170
RR++
Sbjct: 3714 WRRQL 3718
>AJ608772-1|CAE75584.1| 4022|Homo sapiens VPS13B-1A protein protein.
Length = 4022
Score = 42.7 bits (96), Expect = 0.009
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 21/125 (16%)
Query: 1067 FERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVT------ 1120
FER +F TA L + H+ ++A ++GS+D LG+P V + GV
Sbjct: 3619 FERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLP 3678
Query: 1121 --------GLLLEG---NVGALLKNVTHGISNSAAKVSESLGDGLERVVWDEAH----EE 1165
G + G + +K+++ G S ++ SL ++R+ DE H EE
Sbjct: 3679 YEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEE 3738
Query: 1166 TRRRI 1170
RR++
Sbjct: 3739 WRRQL 3743
>AB011104-1|BAA25458.1| 1637|Homo sapiens KIAA0532 protein protein.
Length = 1637
Score = 42.7 bits (96), Expect = 0.009
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 21/125 (16%)
Query: 1067 FERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSEGVT------ 1120
FER +F TA L + H+ ++A ++GS+D LG+P V + GV
Sbjct: 1234 FERGPIFTTARQLVHALAMHYAAGALFRAGWVVGSLDILGSPASLVRSIGNGVADFFRLP 1293
Query: 1121 --------GLLLEG---NVGALLKNVTHGISNSAAKVSESLGDGLERVVWDEAH----EE 1165
G + G + +K+++ G S ++ SL ++R+ DE H EE
Sbjct: 1294 YEGLTRGPGAFVSGVSRGTTSFVKHISKGTLTSITNLATSLARNMDRLSLDEEHYNRQEE 1353
Query: 1166 TRRRI 1170
RR++
Sbjct: 1354 WRRQL 1358
>AK128650-1|BAC87549.1| 1662|Homo sapiens protein ( Homo sapiens cDNA
FLJ46809 fis, clone TRACH3035451. ).
Length = 1662
Score = 37.5 bits (83), Expect = 0.33
Identities = 21/74 (28%), Positives = 36/74 (48%)
Query: 1058 EDAAVELEPFERVHVFETASYLGRQMLAHFKDELKWQAAKILGSVDFLGNPLGFVADVSE 1117
+D +L +E + F L ++ H+ ++ Q ++ +D LGNP G + +SE
Sbjct: 1539 DDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSE 1598
Query: 1118 GVTGLLLEGNVGAL 1131
GV L E GA+
Sbjct: 1599 GVEALFYEPFQGAV 1612
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.134 0.413
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 165,459,985
Number of Sequences: 224733
Number of extensions: 6029012
Number of successful extensions: 14150
Number of sequences better than 10.0: 45
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 13795
Number of HSP's gapped (non-prelim): 210
length of query: 1354
length of database: 73,234,838
effective HSP length: 99
effective length of query: 1255
effective length of database: 50,986,271
effective search space: 63987770105
effective search space used: 63987770105
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 71 (32.7 bits)
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