Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002843-TA|BGIBMGA002843-PA|undefined
(1415 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BX784396-2|CAI19414.1| 4387|Homo sapiens vacuolar protein sortin... 425 e-118
BX784395-2|CAI19412.1| 4387|Homo sapiens vacuolar protein sortin... 425 e-118
BX682532-2|CAI23591.1| 4387|Homo sapiens vacuolar protein sortin... 425 e-118
AL162331-1|CAB82724.1| 2270|Homo sapiens hypothetical protein pr... 425 e-118
AL109757-2|CAI22116.1| 4387|Homo sapiens vacuolar protein sortin... 425 e-118
AL031296-2|CAI23164.1| 4387|Homo sapiens vacuolar protein sortin... 425 e-118
AL031276-2|CAI19223.1| 4387|Homo sapiens vacuolar protein sortin... 425 e-118
AJ608775-1|CAE75587.1| 4363|Homo sapiens VPS13D-2A protein protein. 425 e-118
AJ608774-1|CAE75586.1| 4388|Homo sapiens VPS13D-1A protein protein. 425 e-118
AL359204-2|CAI39538.1| 3174|Homo sapiens vacuolar protein sortin... 146 5e-34
AL359204-1|CAI39537.1| 3095|Homo sapiens vacuolar protein sortin... 146 5e-34
AL353710-2|CAH74106.1| 3174|Homo sapiens vacuolar protein sortin... 146 5e-34
AL353710-1|CAH74105.1| 3095|Homo sapiens vacuolar protein sortin... 146 5e-34
AL158159-2|CAI40936.1| 3174|Homo sapiens vacuolar protein sortin... 146 5e-34
AL158159-1|CAI40935.1| 3095|Homo sapiens vacuolar protein sortin... 146 5e-34
AJ626859-1|CAF25186.1| 3069|Homo sapiens chorein 1D protein. 146 5e-34
AJ608769-1|CAE75581.1| 3135|Homo sapiens chorein 2A protein. 146 5e-34
AF337532-1|AAK61861.1| 3174|Homo sapiens chorea-acanthocytosis p... 146 5e-34
AB054005-1|BAB59128.1| 3095|Homo sapiens chorein protein. 146 5e-34
AJ626860-1|CAF25187.1| 3585|Homo sapiens VPS13C-1B protein protein. 145 9e-34
AJ608770-1|CAE75582.1| 3710|Homo sapiens VPS13C-1A protein protein. 145 9e-34
AJ626861-1|CAF25188.1| 3628|Homo sapiens VPS13C-2B protein protein. 87 6e-16
AJ608771-1|CAE75583.1| 3753|Homo sapiens VPS13C-2A protein protein. 87 6e-16
AB037842-1|BAA92659.1| 1463|Homo sapiens KIAA1421 protein protein. 87 6e-16
BC132978-1|AAI32979.1| 412|Homo sapiens VPS13B protein protein. 58 3e-07
BC132976-1|AAI32977.1| 412|Homo sapiens VPS13B protein protein. 58 3e-07
AY223818-1|AAP41106.1| 412|Homo sapiens Cohen syndrome 1 protei... 58 3e-07
AY223817-1|AAP41105.1| 863|Homo sapiens Cohen syndrome 1 protei... 58 3e-07
AY223816-1|AAP41104.1| 1427|Homo sapiens Cohen syndrome 1 protei... 58 3e-07
AY223815-1|AAP41103.1| 3997|Homo sapiens Cohen syndrome 1 protei... 58 3e-07
AY223814-1|AAP41102.1| 4022|Homo sapiens Cohen syndrome 1 protei... 58 3e-07
AK223122-1|BAD96842.1| 412|Homo sapiens Cohen syndrome 1 protei... 58 3e-07
AK000590-1|BAA91275.1| 412|Homo sapiens protein ( Homo sapiens ... 58 3e-07
AJ608773-1|CAE75585.1| 3997|Homo sapiens VPS13B-2A protein protein. 58 3e-07
AJ608772-1|CAE75584.1| 4022|Homo sapiens VPS13B-1A protein protein. 58 3e-07
AK055200-1|BAB70872.1| 799|Homo sapiens protein ( Homo sapiens ... 50 6e-05
BC127017-1|AAI27018.1| 1010|Homo sapiens KIAA0701 protein protein. 48 3e-04
BC014891-1|AAH14891.1| 522|Homo sapiens KIAA0701 protein protein. 48 3e-04
BC113090-1|AAI13091.1| 514|Homo sapiens KIAA0404 protein protein. 47 4e-04
BC110650-1|AAI10651.1| 1938|Homo sapiens hypothetical protein LO... 47 4e-04
BC041619-1|AAH41619.1| 479|Homo sapiens Unknown (protein for IM... 47 4e-04
AB007864-1|BAA23700.1| 1956|Homo sapiens KIAA0404 protein. 47 4e-04
AL139100-5|CAI20353.1| 1440|Homo sapiens RP3-349A12.1 protein. 38 0.20
AL033520-3|CAI20282.1| 1440|Homo sapiens RP3-349A12.1 protein. 38 0.20
AK000309-1|BAA91074.1| 736|Homo sapiens protein ( Homo sapiens ... 38 0.20
AB126777-1|BAD32740.1| 1440|Homo sapiens ICBP90 binding protein ... 38 0.20
AF007833-1|AAC51847.1| 539|Homo sapiens kruppel-related zinc fi... 37 0.60
BC030576-1|AAH30576.1| 412|Homo sapiens KIAA1432 protein protein. 34 3.2
AL136980-2|CAI95004.1| 791|Homo sapiens KIAA1432 protein. 34 3.2
AK074150-1|BAB84976.1| 768|Homo sapiens FLJ00223 protein protein. 34 3.2
AB205401-1|BAE16982.1| 1344|Homo sapiens connexin43-interacting ... 34 3.2
AB037853-1|BAA92670.2| 796|Homo sapiens KIAA1432 protein protein. 34 3.2
>BX784396-2|CAI19414.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>BX784395-2|CAI19412.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>BX682532-2|CAI23591.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>AL162331-1|CAB82724.1| 2270|Homo sapiens hypothetical protein
protein.
Length = 2270
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>AL109757-2|CAI22116.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>AL031296-2|CAI23164.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>AL031276-2|CAI19223.1| 4387|Homo sapiens vacuolar protein sorting 13
homolog D (S. cerevisiae) protein.
Length = 4387
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>AJ608775-1|CAE75587.1| 4363|Homo sapiens VPS13D-2A protein protein.
Length = 4363
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>AJ608774-1|CAE75586.1| 4388|Homo sapiens VPS13D-1A protein protein.
Length = 4388
Score = 425 bits (1048), Expect = e-118
Identities = 322/1063 (30%), Positives = 479/1063 (45%), Gaps = 98/1063 (9%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
MLEGLVAWVLN YLGKYV NLNTDQLS+ALL G VELENLPLKKDAL+ L LP EVKAGF
Sbjct: 1 MLEGLVAWVLNTYLGKYVNNLNTDQLSVALLKGAVELENLPLKKDALKELELPFEVKAGF 60
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IGKV LQIP + PWVI+I L+L+ AP + +++ E E ERK ALL ALE +
Sbjct: 61 IGKVTLQIPFYRPHVDPWVISISSLHLIGAPEKIQDFNDEKEKLLERERKKALLQALEEK 120
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
W+ + + Y W S ++ IVEN++LKI DVHLR+ED VT FA G
Sbjct: 121 WKNDRQQKGESY-------WYSVTASVVTRIVENIELKIQDVHLRFEDGVTNPSHPFAFG 173
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+ ++++ ++ P + K L++ + ++YWD T +L +L EL
Sbjct: 174 ICIKNVSMQNAVNE--------PVQKLMRKKQLDVAEFSIYWDVDCT---LLGDLPQMEL 222
Query: 240 TERMRETWRA-GHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQ 298
E M + + H YVL P A A + R +++PLR R PR+ C + L+T+ L L+ Q
Sbjct: 223 QEAMARSMESRSHHYVLEPVFASALLKRNCSKKPLRSRHSPRIDCDIQLETIPLKLSQLQ 282
Query: 299 YSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYALSCHMPHNRWRHPRPSWXXX 358
Y + + LER R +FR +P V + + R+WW +AL+ ++ R + R +W
Sbjct: 283 YRQIMEFLKELERKERQVKFRRWKPKVAISKNCREWWYFALNANLYEIREQRKRCTWDFM 342
Query: 359 XXXXXXXXXYVRVCLQLVTSXXXXXXXXXXXXXXXFEWN-TPLHVLKPL--------REI 409
Y + E + L +L+ L E+
Sbjct: 343 LHRARDAVSYTDKYFNKLKGGLLSTDDKEEMCRIEEEQSFEELKILRELVHDRFHKQEEL 402
Query: 410 A--MRSVPKTTPVSSP--DRPSSGRSMLVH---WFPQWWGWYXXXXXXXXXXXXXXXXXX 462
A +R +P + P P G ML + WFP W GWY
Sbjct: 403 AESLREPQFDSPGACPGAPEPGGGSGMLQYLQSWFPGWGGWYGQQTPEGNVVEGLSAEQQ 462
Query: 463 XXXXXXXXXXXXXXXXXXELEEEILDVIADSLENNTLLKKDMVFGKFDFVLNKGSFNLLM 522
EE D AD+ NT K+D VF K + L +G+ LL
Sbjct: 463 EQWIPEEILGT----------EEFFDPTADASCMNTYTKRDHVFAKLNLQLQRGTVTLLH 512
Query: 523 DSED----GEESGVELEFVCVRVQTEWRPRGGAAGVHVSLGSLCLTERITPGTLFPVVCA 578
+ E + ++LEF V++ E PR ++ + V LG L L + T GT+FP++
Sbjct: 513 KEQGTPQMNESAFMQLEFSDVKLLAESLPRRNSSLLSVRLGGLFLRDLATEGTMFPLLVF 572
Query: 579 PQGVIRXXXXXXXXXXXXXXXXXXXWCRXXXXXXXXXXXXXSEPLFQLAYEKKPIGLNCD 638
P P+F++ YE+ P + +
Sbjct: 573 PNPQKEVGRVSQSFGLQTT---------SADRSDHYPAADPDGPVFEMLYERNPAHSHFE 623
Query: 639 YKLWVKSASLEVVY-CEALARWAQRFARR-------GWDARLALDSTRATLINHFE-HMV 689
+L V + L ++Y +A+ + A F + G+ + L L A + + M
Sbjct: 624 RRLNVSTRPLNIIYNPQAIKKVADFFYKGKVHTSGFGYQSELELRVAEAARRQYNKLKMQ 683
Query: 690 HAHSVRHRSCYLL-----SERSSWHVELDIWAPQILLVEQLCSRDSALLLVDFGRLRLAN 744
+R LL E W V LDI APQ++ + ++ L++VD GR+ L N
Sbjct: 684 TKAEIRQTLDRLLVGDFIEESKRWTVRLDISAPQVIFPDDFKFKNPVLVVVDLGRMLLTN 743
Query: 745 ANQD---LTHHAPADDEEMF-----MTPCXXXXXX---XXXXXXXXXXXXXXXXXXXXXA 793
+ + A +E F TP
Sbjct: 744 TQDNSRRKSRDGSASEETQFSDDEYKTPLATPPNTPPPESSSSNGEKTPPFSGVEFSEEQ 803
Query: 794 LHPDTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVL 853
L + +Y+RY + +LQI+VGRV+DNWK+ H++++F++ LQ ERR++
Sbjct: 804 LQAHLMSTKMYERYSLSFMDLQIMVGRVKDNWKHVQDIDVGPTHVVEKFNVHLQLERRLI 863
Query: 854 ETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLA-----PLRSEDAPAPQASPATEDD 908
TSDP YP A L G+LP L H+ E K+ AL+ A +++ D + E+
Sbjct: 864 YTSDPKYPGAVLSGNLPDLKIHINEDKISALKNCFALLTTPEMKTSDTQIKEKIFPQEEQ 923
Query: 909 DEASVRSETDRSES----SSHN-----NSTIFMLQFAVDQMSLEVQSRGRSIAEVQVCGV 959
+ S + ++S H S + + +F V+ M L V+S GR I+ ++V G
Sbjct: 924 RGSLQDSVMNLTQSIVLLEQHTREVLVESQLLLAEFKVNCMQLGVESNGRYISVLKVFGT 983
Query: 960 KMAATARPRDXXXXXXXXXXXXXDALQTYGPDFELLVASHKHV 1002
RP D D +QTYG DF+LL+ASHK++
Sbjct: 984 NAHFVKRPYDAEVSLTVHGLLLVDTMQTYGADFDLLMASHKNL 1026
Score = 41.1 bits (92), Expect = 0.028
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1219 NQETIVELIGFAQRVMGPKTSKTQGDVDETRPEXXXXXXXXXXXXXXKREVRTEITFDFH 1278
N ETIVELIGF Q+ + T E E TE+ + H
Sbjct: 1115 NPETIVELIGFLQKSFPKEKDDLSPQPLMTDFERSFREQGTYQSTY---EQNTEVAVEIH 1171
Query: 1279 RLGVLLLR-AALHDGAVVARKIATATLSEAKIQATL 1313
RL +LLLR + + RKIATA++ K+ ++
Sbjct: 1172 RLNLLLLRTVGMANREKYGRKIATASIGGTKVNVSM 1207
>AL359204-2|CAI39538.1| 3174|Homo sapiens vacuolar protein sorting
13 homolog A (S. cerevisiae) protein.
Length = 3174
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AL359204-1|CAI39537.1| 3095|Homo sapiens vacuolar protein sorting
13 homolog A (S. cerevisiae) protein.
Length = 3095
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AL353710-2|CAH74106.1| 3174|Homo sapiens vacuolar protein sorting
13 homolog A (S. cerevisiae) protein.
Length = 3174
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AL353710-1|CAH74105.1| 3095|Homo sapiens vacuolar protein sorting
13 homolog A (S. cerevisiae) protein.
Length = 3095
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AL158159-2|CAI40936.1| 3174|Homo sapiens vacuolar protein sorting
13 homolog A (S. cerevisiae) protein.
Length = 3174
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AL158159-1|CAI40935.1| 3095|Homo sapiens vacuolar protein sorting
13 homolog A (S. cerevisiae) protein.
Length = 3095
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AJ626859-1|CAF25186.1| 3069|Homo sapiens chorein 1D protein.
Length = 3069
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AJ608769-1|CAE75581.1| 3135|Homo sapiens chorein 2A protein.
Length = 3135
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AF337532-1|AAK61861.1| 3174|Homo sapiens chorea-acanthocytosis
protein.
Length = 3174
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AB054005-1|BAB59128.1| 3095|Homo sapiens chorein protein.
Length = 3095
Score = 146 bits (354), Expect = 5e-34
Identities = 94/344 (27%), Positives = 170/344 (49%), Gaps = 15/344 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+ E +V VLN +LG YV +L+T QLS+ + G V L+NL +K++AL L +P +VK G
Sbjct: 2 VFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGH 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
IG ++L IP + + + P +E++YL+ P + ++D E E K L +E
Sbjct: 62 IGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A+ + D + ++ L+ I++NLQ+KI +H+RYED +T + + G
Sbjct: 120 -EAKQKVVDQEQHLPEKQD--TFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAEL--GIA 237
++ Q+L+ ++ D W L + E KL+ L L YW+ + + L++ +
Sbjct: 177 ISLQNLSMQTTDQYWVP--CLHDETEKLVRKLIRLDNLFAYWN-VKSQMFYLSDYDNSLD 233
Query: 238 ELTERM--RETWRAGHAYVLAPTSARARVCRERTEQPLRCRERPRLACQLTLDTVLLNLT 295
+L + G+ +V P SA A++ R P++ ++ L + +
Sbjct: 234 DLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSD--FDFSAPKINLEIELHNIAIEFN 291
Query: 296 SRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
QY + ++ + + +R +P VP+ H R+WW YA+
Sbjct: 292 KPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/106 (28%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 801 DSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETSDPVY 860
D YD + I+L+ +Q+L RV DNW+ A + S+ H+L +L+ + ++ D
Sbjct: 703 DRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMV-FMDVRM 761
Query: 861 PRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATE 906
P+ + G LP + +++ KL + ++ E P P+ P TE
Sbjct: 762 PKFKIYGKLPLISLRISDKKLQGIMELI-----ESIPKPE--PVTE 800
>AJ626860-1|CAF25187.1| 3585|Homo sapiens VPS13C-1B protein protein.
Length = 3585
Score = 145 bits (352), Expect = 9e-34
Identities = 100/346 (28%), Positives = 173/346 (50%), Gaps = 19/346 (5%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+LE +VA +LN +LG YVENLN QL + + G V L+NL +K++AL L +P +VKAG
Sbjct: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
I K+ L+IP + + V +E LYL+ P ++D+ E + K L +E
Sbjct: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A +A++ + ++ L +++N+Q+KI D+H++YED VT R + G
Sbjct: 120 -EALQKAAEKDKPKEAKKD--TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+T L+ + + W +L + + +KL+ L L+ YW+ + S + I L
Sbjct: 177 VTLGELSLLTANEHWTP--CILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQI--L 232
Query: 240 TERMRETWRAG-----HAYVLAPTSARARV-CRERTEQPLRCRERPRLACQLTLDTVLLN 293
+ E +G + Y+ P SA A++ E L+ P+L C + + + +
Sbjct: 233 DQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELK---TPKLDCNIEIQNIAIE 289
Query: 294 LTSRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
LT QY + ++ + R +R +P +P+ + R WW YA+
Sbjct: 290 LTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Query: 797 DTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETS 856
+ + D YD++ +E+ +Q+L R + WK + S++H+L I ++ + ++E
Sbjct: 696 EEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVE-K 754
Query: 857 DPVYPRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATEDDDEAS 912
D R + G LP + +++ K ++ VL + S P PQ S A + + S
Sbjct: 755 DIRMARFKVSGGLPLMHVRISDQK---MKDVLYLMNS--IPLPQKSSAQSPERQVS 805
>AJ608770-1|CAE75582.1| 3710|Homo sapiens VPS13C-1A protein protein.
Length = 3710
Score = 145 bits (352), Expect = 9e-34
Identities = 100/346 (28%), Positives = 173/346 (50%), Gaps = 19/346 (5%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+LE +VA +LN +LG YVENLN QL + + G V L+NL +K++AL L +P +VKAG
Sbjct: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQ 120
I K+ L+IP + + V +E LYL+ P ++D+ E + K L +E
Sbjct: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIE-- 119
Query: 121 WRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVT-CGRAFACG 179
A +A++ + ++ L +++N+Q+KI D+H++YED VT R + G
Sbjct: 120 -EALQKAAEKDKPKEAKKD--TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFG 176
Query: 180 LTAQSLAAESCDASWKKWFSLLPDPEGRSHKLLELQQLALYWDPISTPSAMLAELGIAEL 239
+T L+ + + W +L + + +KL+ L L+ YW+ + S + I L
Sbjct: 177 VTLGELSLLTANEHWTP--CILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQI--L 232
Query: 240 TERMRETWRAG-----HAYVLAPTSARARV-CRERTEQPLRCRERPRLACQLTLDTVLLN 293
+ E +G + Y+ P SA A++ E L+ P+L C + + + +
Sbjct: 233 DQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELK---TPKLDCNIEIQNIAIE 289
Query: 294 LTSRQYSEAVGCALGLERIGRVREFRALRPSVPVKGHVRDWWIYAL 339
LT QY + ++ + R +R +P +P+ + R WW YA+
Sbjct: 290 LTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAI 335
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Query: 797 DTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETS 856
+ + D YD++ +E+ +Q+L R + WK + S++H+L I ++ + ++E
Sbjct: 696 EEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVE-K 754
Query: 857 DPVYPRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATEDDDEAS 912
D R + G LP + +++ K ++ VL + S P PQ S A + + S
Sbjct: 755 DIRMARFKVSGGLPLMHVRISDQK---MKDVLYLMNS--IPLPQKSSAQSPERQVS 805
>AJ626861-1|CAF25188.1| 3628|Homo sapiens VPS13C-2B protein protein.
Length = 3628
Score = 86.6 bits (205), Expect = 6e-16
Identities = 49/134 (36%), Positives = 77/134 (57%), Gaps = 1/134 (0%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+LE +VA +LN +LG YVENLN QL + + G V L+NL +K++AL L +P +VKAG
Sbjct: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDAL-EA 119
I K+ L+IP + + V +E LYL+ P ++D+ E + K L + EA
Sbjct: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121
Query: 120 QWRAEHEASDAGYY 133
+A + + +G +
Sbjct: 122 LQKAAEKGTHSGEF 135
Score = 77.0 bits (181), Expect = 5e-13
Identities = 52/200 (26%), Positives = 96/200 (48%), Gaps = 14/200 (7%)
Query: 147 LLANIVENLQLKIIDVHLRYEDTVTCG-RAFACGLTAQSLAAESCDASWKKWFSLLPDPE 205
L +++N+Q+KI D+H++YED VT R + G+T L+ + + W +L + +
Sbjct: 186 LATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTP--CILNEAD 243
Query: 206 GRSHKLLELQQLALYWDPISTPSAMLAELGIAELTERMRETWRAG-----HAYVLAPTSA 260
+KL+ L L+ YW+ + S + I L + E +G + Y+ P SA
Sbjct: 244 KIIYKLIRLDSLSAYWNVNCSMSYQRSREQI--LDQLKNEILTSGNIPPNYQYIFQPISA 301
Query: 261 RARV-CRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQYSEAVGCALGLERIGRVREFR 319
A++ E L+ P+L C + + + + LT QY + ++ + R +R
Sbjct: 302 SAKLYMNPYAESELKT---PKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYR 358
Query: 320 ALRPSVPVKGHVRDWWIYAL 339
+P +P+ + R WW YA+
Sbjct: 359 KYKPYLPLHTNGRRWWKYAI 378
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Query: 797 DTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETS 856
+ + D YD++ +E+ +Q+L R + WK + S++H+L I ++ + ++E
Sbjct: 739 EEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVE-K 797
Query: 857 DPVYPRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATEDDDEAS 912
D R + G LP + +++ K ++ VL + S P PQ S A + + S
Sbjct: 798 DIRMARFKVSGGLPLMHVRISDQK---MKDVLYLMNS--IPLPQKSSAQSPERQVS 848
>AJ608771-1|CAE75583.1| 3753|Homo sapiens VPS13C-2A protein protein.
Length = 3753
Score = 86.6 bits (205), Expect = 6e-16
Identities = 49/134 (36%), Positives = 77/134 (57%), Gaps = 1/134 (0%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+LE +VA +LN +LG YVENLN QL + + G V L+NL +K++AL L +P +VKAG
Sbjct: 2 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 61
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDAL-EA 119
I K+ L+IP + + V +E LYL+ P ++D+ E + K L + EA
Sbjct: 62 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 121
Query: 120 QWRAEHEASDAGYY 133
+A + + +G +
Sbjct: 122 LQKAAEKGTHSGEF 135
Score = 77.0 bits (181), Expect = 5e-13
Identities = 52/200 (26%), Positives = 96/200 (48%), Gaps = 14/200 (7%)
Query: 147 LLANIVENLQLKIIDVHLRYEDTVTCG-RAFACGLTAQSLAAESCDASWKKWFSLLPDPE 205
L +++N+Q+KI D+H++YED VT R + G+T L+ + + W +L + +
Sbjct: 186 LATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTP--CILNEAD 243
Query: 206 GRSHKLLELQQLALYWDPISTPSAMLAELGIAELTERMRETWRAG-----HAYVLAPTSA 260
+KL+ L L+ YW+ + S + I L + E +G + Y+ P SA
Sbjct: 244 KIIYKLIRLDSLSAYWNVNCSMSYQRSREQI--LDQLKNEILTSGNIPPNYQYIFQPISA 301
Query: 261 RARV-CRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQYSEAVGCALGLERIGRVREFR 319
A++ E L+ P+L C + + + + LT QY + ++ + R +R
Sbjct: 302 SAKLYMNPYAESELKT---PKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYR 358
Query: 320 ALRPSVPVKGHVRDWWIYAL 339
+P +P+ + R WW YA+
Sbjct: 359 KYKPYLPLHTNGRRWWKYAI 378
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Query: 797 DTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETS 856
+ + D YD++ +E+ +Q+L R + WK + S++H+L I ++ + ++E
Sbjct: 739 EEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVE-K 797
Query: 857 DPVYPRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATEDDDEAS 912
D R + G LP + +++ K ++ VL + S P PQ S A + + S
Sbjct: 798 DIRMARFKVSGGLPLMHVRISDQK---MKDVLYLMNS--IPLPQKSSAQSPERQVS 848
>AB037842-1|BAA92659.1| 1463|Homo sapiens KIAA1421 protein protein.
Length = 1463
Score = 86.6 bits (205), Expect = 6e-16
Identities = 49/134 (36%), Positives = 77/134 (57%), Gaps = 1/134 (0%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRHLGLPVEVKAGF 60
+LE +VA +LN +LG YVENLN QL + + G V L+NL +K++AL L +P +VKAG
Sbjct: 26 VLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQ 85
Query: 61 IGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDAL-EA 119
I K+ L+IP + + V +E LYL+ P ++D+ E + K L + EA
Sbjct: 86 IDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEA 145
Query: 120 QWRAEHEASDAGYY 133
+A + + +G +
Sbjct: 146 LQKAAEKGTHSGEF 159
Score = 77.0 bits (181), Expect = 5e-13
Identities = 52/200 (26%), Positives = 96/200 (48%), Gaps = 14/200 (7%)
Query: 147 LLANIVENLQLKIIDVHLRYEDTVTCG-RAFACGLTAQSLAAESCDASWKKWFSLLPDPE 205
L +++N+Q+KI D+H++YED VT R + G+T L+ + + W +L + +
Sbjct: 210 LATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTP--CILNEAD 267
Query: 206 GRSHKLLELQQLALYWDPISTPSAMLAELGIAELTERMRETWRAG-----HAYVLAPTSA 260
+KL+ L L+ YW+ + S + I L + E +G + Y+ P SA
Sbjct: 268 KIIYKLIRLDSLSAYWNVNCSMSYQRSREQI--LDQLKNEILTSGNIPPNYQYIFQPISA 325
Query: 261 RARV-CRERTEQPLRCRERPRLACQLTLDTVLLNLTSRQYSEAVGCALGLERIGRVREFR 319
A++ E L+ P+L C + + + + LT QY + ++ + R +R
Sbjct: 326 SAKLYMNPYAESELKT---PKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYR 382
Query: 320 ALRPSVPVKGHVRDWWIYAL 339
+P +P+ + R WW YA+
Sbjct: 383 KYKPYLPLHTNGRRWWKYAI 402
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/116 (25%), Positives = 57/116 (49%), Gaps = 6/116 (5%)
Query: 797 DTLHDSIYDRYKIELSELQILVGRVRDNWKYAHTKTTSSLHLLDRFSISLQAERRVLETS 856
+ + D YD++ +E+ +Q+L R + WK + S++H+L I ++ + ++E
Sbjct: 763 EEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVE-K 821
Query: 857 DPVYPRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDAPAPQASPATEDDDEAS 912
D R + G LP + +++ K ++ VL + S P PQ S A + + S
Sbjct: 822 DIRMARFKVSGGLPLMHVRISDQK---MKDVLYLMNS--IPLPQKSSAQSPERQVS 872
>BC132978-1|AAI32979.1| 412|Homo sapiens VPS13B protein protein.
Length = 412
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>BC132976-1|AAI32977.1| 412|Homo sapiens VPS13B protein protein.
Length = 412
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AY223818-1|AAP41106.1| 412|Homo sapiens Cohen syndrome 1 protein
splice variant 4 protein.
Length = 412
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AY223817-1|AAP41105.1| 863|Homo sapiens Cohen syndrome 1 protein
splice variant 3 protein.
Length = 863
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AY223816-1|AAP41104.1| 1427|Homo sapiens Cohen syndrome 1 protein
splice variant 2 protein.
Length = 1427
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AY223815-1|AAP41103.1| 3997|Homo sapiens Cohen syndrome 1 protein
splice variant 1 protein.
Length = 3997
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AY223814-1|AAP41102.1| 4022|Homo sapiens Cohen syndrome 1 protein
protein.
Length = 4022
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AK223122-1|BAD96842.1| 412|Homo sapiens Cohen syndrome 1 protein
isoform 4 variant protein.
Length = 412
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AK000590-1|BAA91275.1| 412|Homo sapiens protein ( Homo sapiens
cDNA FLJ20583 fis, clone KAT09685. ).
Length = 412
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AJ608773-1|CAE75585.1| 3997|Homo sapiens VPS13B-2A protein protein.
Length = 3997
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AJ608772-1|CAE75584.1| 4022|Homo sapiens VPS13B-1A protein protein.
Length = 4022
Score = 57.6 bits (133), Expect = 3e-07
Identities = 46/172 (26%), Positives = 81/172 (47%), Gaps = 7/172 (4%)
Query: 1 MLEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDAL-RHLGLPVEVKAG 59
MLE V +L +Y+ +Y++NL L ++L G V L L LK D L + L LP +G
Sbjct: 1 MLESYVTPILMSYVNRYIKNLKPSDLQLSLWGGDVVLSKLELKLDVLEQELKLPFTFLSG 60
Query: 60 FIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEA 119
I ++++ +P ++ S P VI I + + + + D E+ ++ R A
Sbjct: 61 HIHELRIHVPWTKLGSEPVVITINTMECILKLKDGIQDDHESCGSNSTNRSTAESTKSSI 120
Query: 120 QWRAEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRY-EDTV 170
+ R +A+ T Y L+ +V N+ + I ++ L+Y ED +
Sbjct: 121 KPRRMQQAA-----PTDPDLPPGYVQSLIRRVVNNVNIVINNLILKYVEDDI 167
>AK055200-1|BAB70872.1| 799|Homo sapiens protein ( Homo sapiens
cDNA FLJ30638 fis, clone CTONG2002721, weakly similar to
VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13. ).
Length = 799
Score = 50.0 bits (114), Expect = 6e-05
Identities = 57/262 (21%), Positives = 100/262 (38%), Gaps = 13/262 (4%)
Query: 8 WVLNNYLGKYV-ENLNTDQLSIALLSGKVELENLPLKK----DALRHLGLPVEVKAGFIG 62
++L YLG ++ E L+ +QLS+ L G L +PL K + L P+EV GFI
Sbjct: 16 YLLQRYLGHFLQEKLSLEQLSLDLYQGTGSLAQVPLDKWCLNEILESADAPLEVTEGFIQ 75
Query: 63 KVQLQIPVRQIRSAPWVIAIEKLYLVAAPVNLDEWDSEAEAHHAHERKVALLDALEAQWR 122
+ L +P + + + L +V P SE + L A+
Sbjct: 76 SISLSVPWGSLLQDNCALEVRGLEMVFRPRPRPATGSEPMYWSSFMTSSMQL----AKEC 131
Query: 123 AEHEASDAGYYATSYSSWLSYGTGLLANIVENLQLKIIDVHLRYEDTVTCGRAFACGLTA 182
+ +D + L + ++ +++ ID LR E + L
Sbjct: 132 LSQKLTDEQGEGSQPFEGLEKFAETIETVLRRVKVTFIDTVLRIEHVPENSKT-GTALEI 190
Query: 183 QSLAAESCDASWKKWFSL-LPDPEGRSHKLLELQQLALYWDPI--STPSAMLAELGIAEL 239
+ CD + + + + P +HKLL+L ++L+WD S S+ + E
Sbjct: 191 RIERTVYCDETADESSGINVHQPTAFAHKLLQLSGVSLFWDEFSASAKSSPVCSTAPVET 250
Query: 240 TERMRETWRAGHAYVLAPTSAR 261
++ +W Y P R
Sbjct: 251 EPKLSPSWNPKIIYEPHPQLTR 272
>BC127017-1|AAI27018.1| 1010|Homo sapiens KIAA0701 protein
protein.
Length = 1010
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/89 (24%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Query: 2 LEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRH-LGLP--VEVKA 58
+ G++ + +L ++ +NL+ D+++++ L G+ EL+NL L ++ L++ L LP + +
Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINK 60
Query: 59 GFIGKVQLQIPVRQIRSAPWVIAIEKLYL 87
F K ++IP ++++ P ++++K+ +
Sbjct: 61 VFCNKASIRIPWTKLKTHPICLSLDKVIM 89
>BC014891-1|AAH14891.1| 522|Homo sapiens KIAA0701 protein
protein.
Length = 522
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/89 (24%), Positives = 56/89 (62%), Gaps = 3/89 (3%)
Query: 2 LEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRH-LGLP--VEVKA 58
+ G++ + +L ++ +NL+ D+++++ L G+ EL+NL L ++ L++ L LP + +
Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGELKNLELDEEVLQNMLDLPTWLAINK 60
Query: 59 GFIGKVQLQIPVRQIRSAPWVIAIEKLYL 87
F K ++IP ++++ P ++++K+ +
Sbjct: 61 VFCNKASIRIPWTKLKTHPICLSLDKVIM 89
>BC113090-1|AAI13091.1| 514|Homo sapiens KIAA0404 protein protein.
Length = 514
Score = 47.2 bits (107), Expect = 4e-04
Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 3 EGLVAWVLNNYLGKYV-ENLNTDQLSIALLSGKVELENLPLK----KDALRHLGLPVEVK 57
E + ++L++YLG + E+L+ DQLS+ L G V L ++ L+ + L + P+E+
Sbjct: 14 ERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELV 73
Query: 58 AGFIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAP 91
GF+G +++ +P + + + + L L P
Sbjct: 74 EGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP 107
>BC110650-1|AAI10651.1| 1938|Homo sapiens hypothetical protein
LOC23130 protein.
Length = 1938
Score = 47.2 bits (107), Expect = 4e-04
Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 3 EGLVAWVLNNYLGKYV-ENLNTDQLSIALLSGKVELENLPLK----KDALRHLGLPVEVK 57
E + ++L++YLG + E+L+ DQLS+ L G V L ++ L+ + L + P+E+
Sbjct: 14 ERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELV 73
Query: 58 AGFIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAP 91
GF+G +++ +P + + + + L L P
Sbjct: 74 EGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP 107
>BC041619-1|AAH41619.1| 479|Homo sapiens Unknown (protein for
IMAGE:5923662) protein.
Length = 479
Score = 47.2 bits (107), Expect = 4e-04
Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 3 EGLVAWVLNNYLGKYV-ENLNTDQLSIALLSGKVELENLPLK----KDALRHLGLPVEVK 57
E + ++L++YLG + E+L+ DQLS+ L G V L ++ L+ + L + P+E+
Sbjct: 32 ERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELV 91
Query: 58 AGFIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAP 91
GF+G +++ +P + + + + L L P
Sbjct: 92 EGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP 125
>AB007864-1|BAA23700.1| 1956|Homo sapiens KIAA0404 protein.
Length = 1956
Score = 47.2 bits (107), Expect = 4e-04
Identities = 26/94 (27%), Positives = 51/94 (54%), Gaps = 5/94 (5%)
Query: 3 EGLVAWVLNNYLGKYV-ENLNTDQLSIALLSGKVELENLPLK----KDALRHLGLPVEVK 57
E + ++L++YLG + E+L+ DQLS+ L G V L ++ L+ + L + P+E+
Sbjct: 32 ERVCRYLLHHYLGHFFQEHLSLDQLSLDLYKGSVALRDIHLEIWSVNEVLESMESPLELV 91
Query: 58 AGFIGKVQLQIPVRQIRSAPWVIAIEKLYLVAAP 91
GF+G +++ +P + + + + L L P
Sbjct: 92 EGFVGSIEVAVPWAALLTDHCTVRVSGLQLTLQP 125
>AL139100-5|CAI20353.1| 1440|Homo sapiens RP3-349A12.1 protein.
Length = 1440
Score = 38.3 bits (85), Expect = 0.20
Identities = 18/87 (20%), Positives = 52/87 (59%), Gaps = 3/87 (3%)
Query: 2 LEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRH-LGLP--VEVKA 58
+ G++ + +L ++ +NL+ D+++++ L G+ +L NL L ++ L++ L LP + +
Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGQLTNLELDEEVLQNVLELPTWLAITR 60
Query: 59 GFIGKVQLQIPVRQIRSAPWVIAIEKL 85
+ + ++I ++++ P + ++K+
Sbjct: 61 VYCNRASIRIQWTKLKTHPICLCLDKV 87
>AL033520-3|CAI20282.1| 1440|Homo sapiens RP3-349A12.1 protein.
Length = 1440
Score = 38.3 bits (85), Expect = 0.20
Identities = 18/87 (20%), Positives = 52/87 (59%), Gaps = 3/87 (3%)
Query: 2 LEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRH-LGLP--VEVKA 58
+ G++ + +L ++ +NL+ D+++++ L G+ +L NL L ++ L++ L LP + +
Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGQLTNLELDEEVLQNVLELPTWLAITR 60
Query: 59 GFIGKVQLQIPVRQIRSAPWVIAIEKL 85
+ + ++I ++++ P + ++K+
Sbjct: 61 VYCNRASIRIQWTKLKTHPICLCLDKV 87
>AK000309-1|BAA91074.1| 736|Homo sapiens protein ( Homo sapiens
cDNA FLJ20302 fis, clone HEP06648. ).
Length = 736
Score = 38.3 bits (85), Expect = 0.20
Identities = 18/87 (20%), Positives = 52/87 (59%), Gaps = 3/87 (3%)
Query: 2 LEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRH-LGLP--VEVKA 58
+ G++ + +L ++ +NL+ D+++++ L G+ +L NL L ++ L++ L LP + +
Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGQLTNLELDEEVLQNVLELPTWLAITR 60
Query: 59 GFIGKVQLQIPVRQIRSAPWVIAIEKL 85
+ + ++I ++++ P + ++K+
Sbjct: 61 VYCNRASIRIQWTKLKTHPICLCLDKV 87
>AB126777-1|BAD32740.1| 1440|Homo sapiens ICBP90 binding protein 1
protein.
Length = 1440
Score = 38.3 bits (85), Expect = 0.20
Identities = 18/87 (20%), Positives = 52/87 (59%), Gaps = 3/87 (3%)
Query: 2 LEGLVAWVLNNYLGKYVENLNTDQLSIALLSGKVELENLPLKKDALRH-LGLP--VEVKA 58
+ G++ + +L ++ +NL+ D+++++ L G+ +L NL L ++ L++ L LP + +
Sbjct: 1 MAGIIKKQILKHLSRFTKNLSPDKINLSTLKGEGQLTNLELDEEVLQNVLELPTWLAITR 60
Query: 59 GFIGKVQLQIPVRQIRSAPWVIAIEKL 85
+ + ++I ++++ P + ++K+
Sbjct: 61 VYCNRASIRIQWTKLKTHPICLCLDKV 87
>AF007833-1|AAC51847.1| 539|Homo sapiens kruppel-related zinc
finger protein hcKrox protein.
Length = 539
Score = 36.7 bits (81), Expect = 0.60
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 837 HLLDRFSISLQAERRVLETSDPVYPRAALCGSLPALVAHLTEHKLCALRAVLAPLRSEDA 896
HL + + ++ RR + + P YP + + PA + L+ L R LA + A
Sbjct: 448 HLKGQNCLEVRTRRRRKDDAPPHYPPPSTAAAFPAGL-DLSNGHLDTFRLSLARFWEQSA 506
Query: 897 P--APQASPATEDDDEASVRSETDRSESSSHNN 927
P AP ++P DDDE T ++E + ++
Sbjct: 507 PTWAPVSTPGPPDDDEEEGAPTTPQAEGAMESS 539
>BC030576-1|AAH30576.1| 412|Homo sapiens KIAA1432 protein protein.
Length = 412
Score = 34.3 bits (75), Expect = 3.2
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 10/65 (15%)
Query: 902 SPATEDDDEASVRSETDRSESSS----------HNNSTIFMLQFAVDQMSLEVQSRGRSI 951
SP + DE S+ S TD +ESSS N ST+ + Q ++ +S+E+ S+G
Sbjct: 189 SPLSNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHK 248
Query: 952 AEVQV 956
++VQ+
Sbjct: 249 SQVQL 253
>AL136980-2|CAI95004.1| 791|Homo sapiens KIAA1432 protein.
Length = 791
Score = 34.3 bits (75), Expect = 3.2
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 10/65 (15%)
Query: 902 SPATEDDDEASVRSETDRSESSS----------HNNSTIFMLQFAVDQMSLEVQSRGRSI 951
SP + DE S+ S TD +ESSS N ST+ + Q ++ +S+E+ S+G
Sbjct: 568 SPLSNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHK 627
Query: 952 AEVQV 956
++VQ+
Sbjct: 628 SQVQL 632
>AK074150-1|BAB84976.1| 768|Homo sapiens FLJ00223 protein protein.
Length = 768
Score = 34.3 bits (75), Expect = 3.2
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 10/65 (15%)
Query: 902 SPATEDDDEASVRSETDRSESSS----------HNNSTIFMLQFAVDQMSLEVQSRGRSI 951
SP + DE S+ S TD +ESSS N ST+ + Q ++ +S+E+ S+G
Sbjct: 545 SPLSNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHK 604
Query: 952 AEVQV 956
++VQ+
Sbjct: 605 SQVQL 609
>AB205401-1|BAE16982.1| 1344|Homo sapiens connexin43-interacting
protein of 150 kDa protein.
Length = 1344
Score = 34.3 bits (75), Expect = 3.2
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 10/65 (15%)
Query: 902 SPATEDDDEASVRSETDRSESSS----------HNNSTIFMLQFAVDQMSLEVQSRGRSI 951
SP + DE S+ S TD +ESSS N ST+ + Q ++ +S+E+ S+G
Sbjct: 1121 SPLSNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHK 1180
Query: 952 AEVQV 956
++VQ+
Sbjct: 1181 SQVQL 1185
>AB037853-1|BAA92670.2| 796|Homo sapiens KIAA1432 protein protein.
Length = 796
Score = 34.3 bits (75), Expect = 3.2
Identities = 22/65 (33%), Positives = 36/65 (55%), Gaps = 10/65 (15%)
Query: 902 SPATEDDDEASVRSETDRSESSS----------HNNSTIFMLQFAVDQMSLEVQSRGRSI 951
SP + DE S+ S TD +ESSS N ST+ + Q ++ +S+E+ S+G
Sbjct: 573 SPLSNKGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHK 632
Query: 952 AEVQV 956
++VQ+
Sbjct: 633 SQVQL 637
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.133 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 174,756,510
Number of Sequences: 224733
Number of extensions: 6379287
Number of successful extensions: 15920
Number of sequences better than 10.0: 52
Number of HSP's better than 10.0 without gapping: 41
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 15675
Number of HSP's gapped (non-prelim): 188
length of query: 1415
length of database: 73,234,838
effective HSP length: 99
effective length of query: 1316
effective length of database: 50,986,271
effective search space: 67097932636
effective search space used: 67097932636
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 71 (32.7 bits)
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