Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002840-TA|BGIBMGA002840-PA|IPR000633|Vinculin,
IPR000357|HEAT
(2615 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
D86973-1|BAA13209.2| 2675|Homo sapiens KIAA0219 protein. 1492 0.0
AC004812-3|AAC83183.1| 2392|Homo sapiens WUGSC:H_267D11.3 protein. 1492 0.0
U77700-1|AAC51648.1| 1928|Homo sapiens HsGCN1 protein. 1478 0.0
U88836-1|AAD00655.1| 994|Homo sapiens translational activator G... 828 0.0
U88837-1|AAD00656.1| 356|Homo sapiens translational activator G... 138 2e-31
BC021129-1|AAH21129.1| 299|Homo sapiens Unknown (protein for IM... 125 2e-27
BC032335-1|AAH32335.1| 284|Homo sapiens Unknown (protein for IM... 106 9e-22
BC064346-1|AAH64346.1| 247|Homo sapiens GCN1L1 protein protein. 71 6e-11
BC068491-1|AAH68491.1| 873|Homo sapiens KIAA1622 protein. 52 2e-05
AB046842-1|BAB13448.1| 892|Homo sapiens KIAA1622 protein protein. 52 2e-05
BC046177-1|AAH46177.1| 189|Homo sapiens GCN1L1 protein protein. 50 8e-05
AL354661-2|CAH73240.1| 1839|Homo sapiens KIAA0368 protein. 49 3e-04
AL159168-1|CAH73465.1| 1839|Homo sapiens KIAA0368 protein. 49 3e-04
AB002366-1|BAA20823.1| 1441|Homo sapiens KIAA0368 protein. 49 3e-04
BC112201-1|AAI12202.1| 1849|Homo sapiens BTAF1 RNA polymerase II... 48 5e-04
BC030273-1|AAH30273.1| 560|Homo sapiens Unknown (protein for IM... 48 5e-04
AL365398-1|CAI14103.1| 1849|Homo sapiens BTAF1 RNA polymerase II... 48 5e-04
AL359198-2|CAH73478.1| 1849|Homo sapiens BTAF1 RNA polymerase II... 48 5e-04
AJ001017-1|CAA04475.1| 1849|Homo sapiens TBP associated factor p... 48 5e-04
AF038362-1|AAC04573.1| 1849|Homo sapiens TBP-associated factor 1... 48 5e-04
M31786-1|AAA35531.1| 589|Homo sapiens protein ( Human medium tu... 43 0.013
BC132723-1|AAI32724.1| 1479|Homo sapiens CLASP1 protein protein. 43 0.013
BC112940-1|AAI12941.1| 1471|Homo sapiens CLASP1 protein protein. 43 0.013
AF347693-1|AAQ15051.1| 1538|Homo sapiens multiple asters 1 protein. 43 0.013
AB014522-1|BAA31597.1| 1289|Homo sapiens KIAA0622 protein protein. 43 0.013
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 42 0.030
U72395-1|AAB68948.1| 890|Homo sapiens MIP protein. 42 0.030
U72069-1|AAB58254.1| 890|Homo sapiens karyopherin beta2 protein. 42 0.030
U70322-1|AAC50723.1| 890|Homo sapiens transportin protein. 42 0.030
BC040340-1|AAH40340.1| 890|Homo sapiens transportin 1 protein. 42 0.030
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 42 0.030
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 42 0.030
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 42 0.030
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 42 0.039
BC050341-1|AAH50341.1| 1230|Homo sapiens cullin-associated and n... 42 0.039
BC026220-1|AAH26220.1| 1159|Homo sapiens CAND1 protein protein. 42 0.039
AK027404-1|BAB55090.1| 908|Homo sapiens protein ( Homo sapiens ... 42 0.039
AF157326-1|AAF67492.1| 1230|Homo sapiens TIP120 protein protein. 42 0.039
AB020636-1|BAA74852.2| 1277|Homo sapiens KIAA0829 protein protein. 42 0.039
CR450340-1|CAG29336.1| 589|Homo sapiens PPP2R1A protein. 41 0.052
BC001537-1|AAH01537.1| 589|Homo sapiens protein phosphatase 2 (... 41 0.052
J02902-1|AAA36399.1| 589|Homo sapiens phosphatase 2A regulatory... 41 0.069
BC072420-1|AAH72420.1| 887|Homo sapiens transportin 2 (importin... 40 0.091
BC027596-1|AAH27596.1| 667|Homo sapiens protein phosphatase 2 (... 40 0.091
BC018314-1|AAH18314.1| 771|Homo sapiens Unknown (protein for IM... 40 0.091
AF163473-1|AAG39644.1| 601|Homo sapiens protein phosphatase 2A ... 40 0.091
AF087438-1|AAC69624.1| 601|Homo sapiens protein phosphatase 2 s... 40 0.091
AF083439-1|AAC63525.1| 601|Homo sapiens protein phosphatase 2A ... 40 0.091
AF019039-1|AAB83973.1| 896|Homo sapiens transportin2 protein. 40 0.091
AB210011-1|BAE06093.1| 1051|Homo sapiens TNPO2 variant protein p... 40 0.091
M65254-1|AAA59983.1| 575|Homo sapiens protein phosphatase-2A re... 40 0.12
BC030006-1|AAH30006.1| 956|Homo sapiens C20orf132 protein protein. 40 0.12
AL136172-8|CAI95720.1| 669|Homo sapiens chromosome 20 open read... 40 0.12
AL136172-5|CAI95718.2| 1068|Homo sapiens chromosome 20 open read... 40 0.12
AL031659-4|CAI42665.2| 1068|Homo sapiens chromosome 20 open read... 40 0.12
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 39 0.21
BC047240-1|AAH47240.1| 855|Homo sapiens HEAT repeat containing ... 39 0.28
AF007748-1|AAB71349.1| 887|Homo sapiens karyopherin beta2b homo... 38 0.37
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 38 0.48
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 38 0.48
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 38 0.48
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 38 0.48
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 38 0.48
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 38 0.48
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 38 0.48
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 38 0.48
AK027783-1|BAB55365.1| 403|Homo sapiens protein ( Homo sapiens ... 38 0.64
AK091387-1|BAC03652.1| 509|Homo sapiens protein ( Homo sapiens ... 37 1.1
BC125109-1|AAI25110.1| 782|Homo sapiens Vac14 homolog (S. cerev... 36 1.5
BC125108-1|AAI25109.1| 782|Homo sapiens Vac14 homolog (S. cerev... 36 1.5
BX640725-1|CAE45842.1| 709|Homo sapiens hypothetical protein pr... 36 2.0
BC011530-1|AAH11530.1| 857|Homo sapiens Unknown (protein for IM... 36 2.0
AL137636-1|CAB70852.1| 356|Homo sapiens hypothetical protein pr... 36 2.0
AB014527-1|BAA31602.1| 1324|Homo sapiens KIAA0627 protein protein. 36 2.0
CR456567-1|CAG30453.1| 348|Homo sapiens RTDR1 protein. 36 2.6
BC117129-1|AAI17130.1| 1030|Homo sapiens MMS19-like (MET18 homol... 36 2.6
BC080532-1|AAH80532.1| 871|Homo sapiens MMS19L protein protein. 36 2.6
BC008986-1|AAH08986.1| 348|Homo sapiens rhabdoid tumor deletion... 36 2.6
BC006575-1|AAH06575.2| 803|Homo sapiens MMS19L protein protein. 36 2.6
AY974244-1|AAX59033.1| 1030|Homo sapiens MMS19-like (MET18 homol... 36 2.6
AL359388-1|CAI14189.1| 1030|Homo sapiens MMS19-like (MET18 homol... 36 2.6
AL355490-1|CAI40770.1| 1030|Homo sapiens MMS19-like (MET18 homol... 36 2.6
AJ306408-1|CAC29239.1| 1030|Homo sapiens MMS19 protein protein. 36 2.6
AF357881-1|AAK70402.1| 1030|Homo sapiens transcriptional coactiv... 36 2.6
AF319947-1|AAK52668.1| 1030|Homo sapiens MMS19 protein. 36 2.6
AF133587-1|AAF02484.1| 348|Homo sapiens rhabdoid tumor deletion... 36 2.6
Z68228-1|CAA92522.1| 745|Homo sapiens plakoglobin protein. 35 3.4
Y08890-1|CAA70103.1| 1097|Homo sapiens Ran_GTP binding protein 5... 35 3.4
M23410-1|AAA64895.1| 744|Homo sapiens Plakoglobin protein. 35 3.4
BC045640-1|AAH45640.1| 1115|Homo sapiens RAN binding protein 5 p... 35 3.4
BC019309-1|AAH19309.1| 1097|Homo sapiens RANBP5 protein protein. 35 3.4
BC011865-1|AAH11865.1| 745|Homo sapiens JUP protein protein. 35 3.4
BC001497-1|AAH01497.1| 1097|Homo sapiens RANBP5 protein protein. 35 3.4
BC000441-1|AAH00441.2| 784|Homo sapiens JUP protein protein. 35 3.4
AY243535-1|AAO85780.1| 745|Homo sapiens gamma-catenin protein. 35 3.4
AL356580-2|CAI13757.1| 1097|Homo sapiens RAN binding protein 5 p... 35 3.4
AL137120-1|CAI16520.1| 1097|Homo sapiens RAN binding protein 5 p... 35 3.4
AF306723-1|AAG16727.1| 745|Homo sapiens plakoglobin protein. 35 3.4
BC032563-1|AAH32563.1| 149|Homo sapiens CLASP1 protein protein. 35 4.5
BC021127-1|AAH21127.1| 519|Homo sapiens KIAA0368 protein protein. 35 4.5
AL355490-23|CAI40792.1| 885|Homo sapiens MMS19-like (MET18 homo... 35 4.5
AK027710-1|BAB55315.1| 774|Homo sapiens protein ( Homo sapiens ... 35 4.5
AC013399-2|AAX88872.1| 149|Homo sapiens unknown protein. 35 4.5
U02325-1|AAA19950.1| 350|Homo sapiens neu differentiation facto... 34 7.9
M94166-1|AAA58639.1| 645|Homo sapiens heregulin-beta1 protein. 34 7.9
M94165-1|AAA58638.1| 640|Homo sapiens heregulin-alpha protein. 34 7.9
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 34 7.9
BC063519-1|AAH63519.1| 613|Homo sapiens PHLPP protein protein. 34 7.9
BC047653-1|AAH47653.1| 656|Homo sapiens PHLPP protein protein. 34 7.9
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 34 7.9
BC010706-1|AAH10706.1| 543|Homo sapiens PHLPP protein protein. 34 7.9
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 34 7.9
>D86973-1|BAA13209.2| 2675|Homo sapiens KIAA0219 protein.
Length = 2675
Score = 1492 bits (3698), Expect = 0.0
Identities = 865/1821 (47%), Positives = 1127/1821 (61%), Gaps = 155/1821 (8%)
Query: 874 LYKPQCDLDPSWEDEDLVEATSRVINLLHXXXXXXXXXXXXTKKLNHFTAPGFCYVFPVV 933
L KP+C LD SW E+L A R + LLH +AP F VFP +
Sbjct: 931 LLKPECVLDKSWCQEELSVAVKRAVMLLHTHTITSRVGKGEPGAAP-LSAPAFSLVFPFL 989
Query: 934 KLGLTK--ELSEKDEMTMLNGLAVITHHVSARPHPDD----AELLHPALFPMDEIFRLLI 987
K+ LT+ SE++E M L ++T R P+ + P L P + RLL
Sbjct: 990 KMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASPNTPPGRVDENGPELLPRVAMLRLLT 1049
Query: 988 ELIE--STRLCAQAACIVALLEAARCXXXXXXXXXXXXXXXXXXXSESEV--VRDTVLQX 1043
+I S RL A+ + L A+ +S VR+TVL+
Sbjct: 1050 WVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAEQEEVDVLLCALQSPCASVRETVLRG 1109
Query: 1044 XXXXXXXXXXXXQDEDYAYSVVKRILIATFDVVEDNKKLAVELWERVPGCEPVSRGALMA 1103
DE ++++R+ + FD E+ +KLA LW + + +
Sbjct: 1110 LMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEEIRKLAERLWSMMG----LDLQPDLC 1165
Query: 1104 DLVLDELQTXXXXXXXXXXXXXXXXXXRGDAPCDVLLQRLQDLYAEKLPLIPAKQDQFGH 1163
L++D++ R ++ RL ++Y EKL P D G
Sbjct: 1166 SLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGR 1225
Query: 1164 EV-EPALDMWEXXXXXXXXXXXXXXXXQVGAVPAVMRFFVEWGLADRRDDVRAEMLAAAM 1222
+ E D WE V + +FFV L DR DVR ML AA+
Sbjct: 1226 VISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFFVPDALNDRHPDVRKCMLDAAL 1285
Query: 1223 AIVELHGKDTISSQLPVFERFLDSAPKSGSYDAVREAVVLLVGSLARHLEPDDVRLRPIA 1282
A + HGK+ ++S LPVFE FL +AP SYDAVR++VV+L+GSLA+HL+ D +++PI
Sbjct: 1286 ATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIV 1345
Query: 1283 LRLVAALSTPAQQVPHPHITSLSVAASSGCRPSVQEAVGNCLPHLVTSPALESEIPGIVN 1342
+L+AALSTP+QQ VQE+V +CLP LV PA++ + G++
Sbjct: 1346 AKLIAALSTPSQQ--------------------VQESVASCLPPLV--PAIKEDAGGMIQ 1383
Query: 1343 KLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKNYKYREGAL 1402
+LM+QLL ++K+ +R+GAAYG+AG+VKGLGILSLKQ ++M LT+AIQ+KKN++ REGAL
Sbjct: 1384 RLMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGAL 1443
Query: 1403 FGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVL 1462
F FE+LC +LG+LFEPY+VHVLPHLLLC GDG+QYVR AADD A+ +MS LSAHGVKLVL
Sbjct: 1444 FAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVL 1503
Query: 1463 PALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAA 1522
P+LL A+ +++WRTKAGS+ELLGAMAYCAPKQLSSCLP+IVP+L EVL+DSH++VQ +
Sbjct: 1504 PSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQ 1563
Query: 1523 AALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPV 1582
AL+ IGSVIRNPEI AI PVLL AL DPS KT CLQTLLDTKFVHFIDAPSLALIMP+
Sbjct: 1564 QALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPI 1623
Query: 1583 VQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSAR 1642
VQRAF DRST+TRKMAAQIIGNMYSLTDQKDL PYLP++ PGLK+SLLDPVPEVR+VSA+
Sbjct: 1624 VQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAK 1683
Query: 1643 ALGAMVKGMGESSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQKLHKIMPGD 1702
ALGAMVKGMGES FE+LLPWLM TLT E SSVDRSGAAQGL+EV+AGLGV+KL K+MP
Sbjct: 1684 ALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMP-- 1741
Query: 1703 TPACNRNKVIPTYIIATAERTDIAPHVKDGYIMMFIYMPGAFTDEFTPYIGQIINPILKA 1762
I+ATA + DIAPHV+DGYIMMF Y+P F D+FTPY+G II ILKA
Sbjct: 1742 ------------EIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKA 1789
Query: 1763 LADENEYVRETALRAGQRIVNLYAESAIALLLPELEKGLFDDNWRIRYSSVQLLGDLLYR 1822
LADENE+VR+TALRAGQR++++YAE+AIALLLP+LE+GLFDD WRIR+SSVQLLGDLL+
Sbjct: 1790 LADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFH 1849
Query: 1823 ISGVTGKMSTETASEDDNFGTEQSHKAIITALGPERRNRVLAGLYMGRSDVALMVRQAAL 1882
ISGVTGKM+TETASEDDNFGT QS+KAIITALG ERRNRVLAGLYMGRSD L+VRQA+L
Sbjct: 1850 ISGVTGKMTTETASEDDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASL 1909
Query: 1883 HSY---------DKRQVAARTLGDLV---------------RKLGERV-------LPEIV 1911
H + R++ G L+ R LG+ V LPEI+
Sbjct: 1910 HVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEII 1969
Query: 1912 PILERGLRSPRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAA 1971
PILE GLRS ++D+RQGVCIGL EI+ STSRDAVL F++ LVPT R ALCDPL EVR AA
Sbjct: 1970 PILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAA 2029
Query: 1972 ARTFDSLHATIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLRIMSIKSRAVLPY 2031
A+TF+ LH+TIG++AL+DILP++L+ L D + V++ LDGLKQ +M+IKSR VLPY
Sbjct: 2030 AKTFEQLHSTIGHQALEDILPFLLKQLDDEE--VSEFALDGLKQ----VMAIKSRVVLPY 2083
Query: 2032 LIPVLTXXXXXXVDTRXXXXXXXXXXXXXXRHVPRVLPALLHALEAARATPHEAAELDHC 2091
L+P LT V+TR RH+ +LPA++ AL+ TP E E+ +C
Sbjct: 2084 LVPKLT---TPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANC 2140
Query: 2092 RDPLLPVTDPPGLRCIIDTLLDTVRSSEGSXXXXXXVLLCAFVAHTRGDLEPHVPQXXXX 2151
+ +L V D G R II+ LL+ RS E ++L + + ++ D H+
Sbjct: 2141 QAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSG 2200
Query: 2152 XXXXXXXXXXXXXXMAWEALSALTKTLDAERQIQHVSDVRQAVRYAAADLKGDLLPGFCL 2211
+W+AL+A+TK LDA Q+ + ++ + +R + KG+ +PGFCL
Sbjct: 2201 LIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCL 2260
Query: 2212 PKVMWDISGRLWRCYRQLRAIYTSLTGIAPILPLFRESILNGLPEDKENAALMLGEVIKL 2271
PK G+ ILP+ RE +L G PE KE AA LG VI+L
Sbjct: 2261 PK-----------------------KGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRL 2297
Query: 2272 TSPAAIQPSVVHITGPLIRILGDRFNSSVKAAVLETLASLLSKVGVMLKQFLPQLQTTFL 2331
TS A++PSVV ITGPLIRILGDRF+ +VKAA+LETL+ LL+KVG+ LK FLPQLQTTF
Sbjct: 2298 TSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIALKPFLPQLQTTFT 2357
Query: 2332 KALNDPNRPVRIKAGLALSQLVIIHTRADPLFVEMHNGIKNTDDPAIRETMLQALRSIIS 2391
KAL D NR VR+KA AL +L+ IH + DPLF E+ NGI+ +DP +R+TMLQALR +I
Sbjct: 2358 KALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGVRDTMLQALRFVIQ 2417
Query: 2392 GGGDKLSEQLALSILSTLTSPALLAHPEDPPRGAVGGCLGALLHWLPSAHHDAALQHHVL 2451
G G K+ + +I+S L S +L H ED R + GCLG L +L A LQ +L
Sbjct: 2418 GAGAKVDAVIRKNIVSLLLS--MLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQCLL 2475
Query: 2452 AQSD--DWLLQHGRSCALFVALKETPASIYRDHYEEKIDKTLLASWPATRSRSSVTSM-- 2507
A DW+++HGRS AL VA+ P + Y + + +L+S A R +V+ +
Sbjct: 2476 ADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATADRIPIAVSGVRG 2535
Query: 2508 ------NHQSNEVKQMMARASGALGREADNPEL-LRAV------------LPAL------ 2542
+H Q+ A+ S + NP +R V LP L
Sbjct: 2536 MGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKDPLPPLDPQAIK 2595
Query: 2543 ------VNGTKEKNSYVRANAESSLRTLLRLHSEPDYFQRCVSFLEEGAREALSDVVARV 2596
++ TK+KN+ VRA ++ ++ LL++ + FQ L+ + E L++V R
Sbjct: 2596 PILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVASLEVLNEVNRRS 2655
Query: 2597 LRR--PQPDGRDEDLDCTLIT 2615
L++ Q D E +D T++T
Sbjct: 2656 LKKLASQADS-TEQVDDTILT 2675
Score = 310 bits (761), Expect = 5e-83
Identities = 242/880 (27%), Positives = 388/880 (44%), Gaps = 25/880 (2%)
Query: 2 ADTEVLKKLKDIPFKIQTASLKGRLEVVNEIREILSSPGITEPAVKFVCRVLALTLHRYR 61
ADT+V + LK K+ TAS+K R E+++E+ + ++ + E AVK +C++ LTLHRYR
Sbjct: 7 ADTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHRYR 66
Query: 62 DTTSQSYIKSLVAFLATEHTEWAFKNLSPVLLEISEQLXXXXXXXXXXXXGLFALRWSSV 121
D S+ +++ + LA E KNL L L AL W+ +
Sbjct: 67 DAASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWTCL 126
Query: 122 LVESS-PKSLEHEVDL-NSLILAQANLLATVCAYGDKKKNKKAYSVLHAVWSKIGKEKVL 179
LV P + + D+ N L+ Q LL V K A L +W K V
Sbjct: 127 LVRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLW-KENPGLVE 185
Query: 180 KWVETLLA-QPGDSGPHISVTFSALCAHYKDIGDESIITLHKAKMLENFTKSLISVKSRP 238
+++ +L+ +P + + C +K++ +++ HK+ +L+ + K+++ K +P
Sbjct: 186 QYLSAILSLEPNQNYAGMLGLLVQFCTSHKEM---DVVSQHKSALLDFYMKNILMSKVKP 242
Query: 239 NANYIKGCSDLLHLLSESDIQDTLLPALHKAMLRSPETIVQAVGEVVANLNIYLDGVAVD 298
+ C+ LL LS S+ +D +LP + K++LRSPE +++ + ++A++ + A+D
Sbjct: 243 PKYLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDFSQYAMD 302
Query: 299 IGKSLIVNLHSKDEWVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYNGASGKLTSSED 358
I K L +L S + G+ GKLT
Sbjct: 303 IVKGLAGHLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQ 362
Query: 359 KIAVLNGVRALSQLAVAPEDRRALFAETAAHTARILDSESHERTLCVALDVLQHWTTGLD 418
K++VL+G+ ++S V+ + L A L E HE TL A+ VL W
Sbjct: 363 KMSVLSGIGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFT 422
Query: 419 GPLPDVILEIFTKNISAKSSTQTVRTAYTSLLGRALRRCGXXXXXXXXXXXXXXXVERAA 478
+P + E F K S K+ST VR AY + A R VE+AA
Sbjct: 423 MEVPKKLTEWFKKAFSLKTSTSAVRHAYLQCM-LASYRGDTLLQALDLLPLLIQTVEKAA 481
Query: 479 LQPLQNATVSEGICAMLGLVLLD--ESRQLPGKSSCWAALLHPDKHVLLHDRVLAAASEH 536
Q Q T++EG+ A L L+ L +S+ SS W ++ K V ++ L ASE
Sbjct: 482 SQSTQVPTITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASED 541
Query: 537 VLIQVALLC-RTVLDHYPSVASEPNSPIYRAFIMVLLSTVKPVREVALQEVRALLAKRDK 595
L V L R LDH + +RA + VLLS VR A Q VR LL+
Sbjct: 542 ALCTVLHLTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGG 601
Query: 596 AATAKHLVLKLNEVLDEGKIFHIKEKSPSDEKGAEVTGKMILD---CAHALCSYKDYP-- 650
A L+ +L VL K+ + E +D GK + ALC P
Sbjct: 602 FKLAHGLLEELKTVLSSHKVLPL-EALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGL 660
Query: 651 ---KEELESIALSALPCSHHPLVKAGAPRAWVKMVSSLGLQPKELVTLYANNLKNTYING 707
+ E +A L SHHP + A W +++ + + P+ +T + + +
Sbjct: 661 KGDVTDTEQLAQEMLIISHHPSLVAVQSGLWPALLARMKIDPEAFITRHLDQIIPRMTTQ 720
Query: 708 FTPXXXXXXXXXXXXXXGPDGMSSSAVQAALVWLQDPQLQRVTRDEYFVYLTPDDDIYDK 767
PD + + +Q+P L+ VTR+E+ + TP ++YDK
Sbjct: 721 SPLNQSSMNAMGSLSVLSPDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDK 780
Query: 768 SSVPGNEDN--KEMNLKRESKAYSYXXXXXXXXXXXXXXXXXXXXGKIKETPLSAKQKEA 825
S + + + K+ N+KRE+KAYS+ G +E L++KQKE
Sbjct: 781 SIIQSAQQDSIKKANMKRENKAYSF---KEQIIELELKEEIKKKKGIKEEVQLTSKQKEM 837
Query: 826 IKAQLAKESAVRKRLSVLNERLVCAVGLLEAVQRGCPSAL 865
++AQL +E+ VR+RL L+ L A+GLL+ + PS L
Sbjct: 838 LQAQLDREAQVRRRLQELDGELEAALGLLDIILAKNPSGL 877
>AC004812-3|AAC83183.1| 2392|Homo sapiens WUGSC:H_267D11.3 protein.
Length = 2392
Score = 1492 bits (3697), Expect = 0.0
Identities = 865/1821 (47%), Positives = 1127/1821 (61%), Gaps = 155/1821 (8%)
Query: 874 LYKPQCDLDPSWEDEDLVEATSRVINLLHXXXXXXXXXXXXTKKLNHFTAPGFCYVFPVV 933
L KP+C LD SW E+L A R + LLH +AP F VFP +
Sbjct: 648 LLKPECVLDKSWCQEELSVAVKRAVMLLHTHTITSRVGKGEPGAAP-LSAPAFSLVFPFL 706
Query: 934 KLGLTK--ELSEKDEMTMLNGLAVITHHVSARPHPDD----AELLHPALFPMDEIFRLLI 987
K+ LT+ SE++E M L ++T R P+ + P L P + RLL
Sbjct: 707 KMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASPNTPPGRVDENGPELLPRVAMLRLLT 766
Query: 988 ELIE--STRLCAQAACIVALLEAARCXXXXXXXXXXXXXXXXXXXSESEV--VRDTVLQX 1043
+I S RL A+ + L A+ +S VR+TVL+
Sbjct: 767 WVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAEQEEVDVLLCALQSPCASVRETVLRG 826
Query: 1044 XXXXXXXXXXXXQDEDYAYSVVKRILIATFDVVEDNKKLAVELWERVPGCEPVSRGALMA 1103
DE ++++R+ + FD E+ +KLA LW + + +
Sbjct: 827 LMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEEIRKLAERLWSMMG----LDLQPDLC 882
Query: 1104 DLVLDELQTXXXXXXXXXXXXXXXXXXRGDAPCDVLLQRLQDLYAEKLPLIPAKQDQFGH 1163
L++D++ R ++ RL ++Y EKL P D G
Sbjct: 883 SLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGR 942
Query: 1164 EV-EPALDMWEXXXXXXXXXXXXXXXXQVGAVPAVMRFFVEWGLADRRDDVRAEMLAAAM 1222
+ E D WE V + +FFV L DR DVR ML AA+
Sbjct: 943 VISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFFVPDALNDRHPDVRKCMLDAAL 1002
Query: 1223 AIVELHGKDTISSQLPVFERFLDSAPKSGSYDAVREAVVLLVGSLARHLEPDDVRLRPIA 1282
A + HGK+ ++S LPVFE FL +AP SYDAVR++VV+L+GSLA+HL+ D +++PI
Sbjct: 1003 ATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIV 1062
Query: 1283 LRLVAALSTPAQQVPHPHITSLSVAASSGCRPSVQEAVGNCLPHLVTSPALESEIPGIVN 1342
+L+AALSTP+QQ VQE+V +CLP LV PA++ + G++
Sbjct: 1063 AKLIAALSTPSQQ--------------------VQESVASCLPPLV--PAIKEDAGGMIQ 1100
Query: 1343 KLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKNYKYREGAL 1402
+LM+QLL ++K+ +R+GAAYG+AG+VKGLGILSLKQ ++M LT+AIQ+KKN++ REGAL
Sbjct: 1101 RLMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGAL 1160
Query: 1403 FGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVL 1462
F FE+LC +LG+LFEPY+VHVLPHLLLC GDG+QYVR AADD A+ +MS LSAHGVKLVL
Sbjct: 1161 FAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVL 1220
Query: 1463 PALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAA 1522
P+LL A+ +++WRTKAGS+ELLGAMAYCAPKQLSSCLP+IVP+L EVL+DSH++VQ +
Sbjct: 1221 PSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQ 1280
Query: 1523 AALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPV 1582
AL+ IGSVIRNPEI AI PVLL AL DPS KT CLQTLLDTKFVHFIDAPSLALIMP+
Sbjct: 1281 QALRQIGSVIRNPEILAIAPVLLDALTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPI 1340
Query: 1583 VQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSAR 1642
VQRAF DRST+TRKMAAQIIGNMYSLTDQKDL PYLP++ PGLK+SLLDPVPEVR+VSA+
Sbjct: 1341 VQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAK 1400
Query: 1643 ALGAMVKGMGESSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQKLHKIMPGD 1702
ALGAMVKGMGES FE+LLPWLM TLT E SSVDRSGAAQGL+EV+AGLGV+KL K+MP
Sbjct: 1401 ALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMP-- 1458
Query: 1703 TPACNRNKVIPTYIIATAERTDIAPHVKDGYIMMFIYMPGAFTDEFTPYIGQIINPILKA 1762
I+ATA + DIAPHV+DGYIMMF Y+P F D+FTPY+G II ILKA
Sbjct: 1459 ------------EIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKA 1506
Query: 1763 LADENEYVRETALRAGQRIVNLYAESAIALLLPELEKGLFDDNWRIRYSSVQLLGDLLYR 1822
LADENE+VR+TALRAGQR++++YAE+AIALLLP+LE+GLFDD WRIR+SSVQLLGDLL+
Sbjct: 1507 LADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFH 1566
Query: 1823 ISGVTGKMSTETASEDDNFGTEQSHKAIITALGPERRNRVLAGLYMGRSDVALMVRQAAL 1882
ISGVTGKM+TETASEDDNFGT QS+KAIITALG ERRNRVLAGLYMGRSD L+VRQA+L
Sbjct: 1567 ISGVTGKMTTETASEDDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASL 1626
Query: 1883 HSY---------DKRQVAARTLGDLV---------------RKLGERV-------LPEIV 1911
H + R++ G L+ R LG+ V LPEI+
Sbjct: 1627 HVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEII 1686
Query: 1912 PILERGLRSPRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAA 1971
PILE GLRS ++D+RQGVCIGL EI+ STSRDAVL F++ LVPT R ALCDPL EVR AA
Sbjct: 1687 PILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAA 1746
Query: 1972 ARTFDSLHATIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLRIMSIKSRAVLPY 2031
A+TF+ LH+TIG++AL+DILP++L+ L D + V++ LDGLKQ +M+IKSR VLPY
Sbjct: 1747 AKTFEQLHSTIGHQALEDILPFLLKQLDDEE--VSEFALDGLKQ----VMAIKSRVVLPY 1800
Query: 2032 LIPVLTXXXXXXVDTRXXXXXXXXXXXXXXRHVPRVLPALLHALEAARATPHEAAELDHC 2091
L+P LT V+TR RH+ +LPA++ AL+ TP E E+ +C
Sbjct: 1801 LVPKLT---TPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANC 1857
Query: 2092 RDPLLPVTDPPGLRCIIDTLLDTVRSSEGSXXXXXXVLLCAFVAHTRGDLEPHVPQXXXX 2151
+ +L V D G R II+ LL+ RS E ++L + + ++ D H+
Sbjct: 1858 QAVILSVEDDTGHRIIIEYLLEATRSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSG 1917
Query: 2152 XXXXXXXXXXXXXXMAWEALSALTKTLDAERQIQHVSDVRQAVRYAAADLKGDLLPGFCL 2211
+W+AL+A+TK LDA Q+ + ++ + +R + KG+ +PGFCL
Sbjct: 1918 LIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCL 1977
Query: 2212 PKVMWDISGRLWRCYRQLRAIYTSLTGIAPILPLFRESILNGLPEDKENAALMLGEVIKL 2271
PK G+ ILP+ RE +L G PE KE AA LG VI+L
Sbjct: 1978 PK-----------------------KGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRL 2014
Query: 2272 TSPAAIQPSVVHITGPLIRILGDRFNSSVKAAVLETLASLLSKVGVMLKQFLPQLQTTFL 2331
TS A++PSVV ITGPLIRILGDRF+ +VKAA+LETL+ LL+KVG+ LK FLPQLQTTF
Sbjct: 2015 TSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIALKPFLPQLQTTFT 2074
Query: 2332 KALNDPNRPVRIKAGLALSQLVIIHTRADPLFVEMHNGIKNTDDPAIRETMLQALRSIIS 2391
KAL D NR VR+KA AL +L+ IH + DPLF E+ NGI+ +DP +R+TMLQALR +I
Sbjct: 2075 KALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGVRDTMLQALRFVIQ 2134
Query: 2392 GGGDKLSEQLALSILSTLTSPALLAHPEDPPRGAVGGCLGALLHWLPSAHHDAALQHHVL 2451
G G K+ + +I+S L S +L H ED R + GCLG L +L A LQ +L
Sbjct: 2135 GAGAKVDAVIRKNIVSLLLS--MLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQCLL 2192
Query: 2452 AQSD--DWLLQHGRSCALFVALKETPASIYRDHYEEKIDKTLLASWPATRSRSSVTSM-- 2507
A DW+++HGRS AL VA+ P + Y + + +L+S A R +V+ +
Sbjct: 2193 ADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATADRIPIAVSGVRG 2252
Query: 2508 ------NHQSNEVKQMMARASGALGREADNPEL-LRAV------------LPAL------ 2542
+H Q+ A+ S + NP +R V LP L
Sbjct: 2253 MGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKDPLPPLDPQAIK 2312
Query: 2543 ------VNGTKEKNSYVRANAESSLRTLLRLHSEPDYFQRCVSFLEEGAREALSDVVARV 2596
++ TK+KN+ VRA ++ ++ LL++ + FQ L+ + E L++V R
Sbjct: 2313 PILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVASLEVLNEVNRRS 2372
Query: 2597 LRR--PQPDGRDEDLDCTLIT 2615
L++ Q D E +D T++T
Sbjct: 2373 LKKLASQADS-TEQVDDTILT 2392
Score = 151 bits (366), Expect = 3e-35
Identities = 126/434 (29%), Positives = 182/434 (41%), Gaps = 13/434 (2%)
Query: 246 CSDLLHLLSESDIQDTLLPALHKAMLRSPETIVQAVGEVVANLNIYLDGVAVDIGKSLIV 305
C+ LL LS S+ +D +LP + K++LRSPE +++ + ++A++ + L A+DI K L
Sbjct: 3 CAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYAMDIVKGLAG 62
Query: 306 NLHSKDEWVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXEYNGASGKLTSSEDKIAVLNG 365
+L S + G+ GKLT K++VL+G
Sbjct: 63 HLKSNSPRLMDEAVLALRNLARQCSDSSAMESLTKHLFAILGGSEGKLTVVAQKMSVLSG 122
Query: 366 VRALSQLAVAPEDRRALFAETAAHTARILDSESHERTLCVALDVLQHWTTGLDGPLPDVI 425
+ ++S V+ + L A L E HE TL A+ VL W +P +
Sbjct: 123 IGSVSHHVVSGPSSQVLNGIVAELFIPFLQQEVHEGTLVHAVSVLALWCNRFTMEVPKKL 182
Query: 426 LEIFTKNISAKSSTQTVRTAYTSLLGRALRRCGXXXXXXXXXXXXXXXVERAALQPLQNA 485
E F K S K+ST VR AY + A R VE+AA Q Q
Sbjct: 183 TEWFKKAFSLKTSTSAVRHAYLQCM-LASYRGDTLLQALDLLPLLIQTVEKAASQSTQVP 241
Query: 486 TVSEGICAMLGLVLLD--ESRQLPGKSSCWAALLHPDKHVLLHDRVLAAASEHVLIQVAL 543
T++EG+ A L L+ L +S+ SS W ++ K V ++ L ASE L V
Sbjct: 242 TITEGVAAALLLLKLSVADSQAEAKLSSFWQLIVDEKKQVFTSEKFLVMASEDALCTVLH 301
Query: 544 LC-RTVLDHYPSVASEPNSPIYRAFIMVLLSTVKPVREVALQEVRALLAKRDKAATAKHL 602
L R LDH + +RA + VLLS VR A Q VR LL+ A L
Sbjct: 302 LTERLFLDHPHRLTGNKVQQYHRALVAVLLSRTWHVRRQAQQTVRKLLSSLGGFKLAHGL 361
Query: 603 VLKLNEVLDEGKIFHIKEKSPSDEKGAEVTGKMILD---CAHALCSYKDYP-----KEEL 654
+ +L VL K+ + E +D GK + ALC P +
Sbjct: 362 LEELKTVLSSHKVLPL-EALVTDAGEVTEAGKAYVPPRVLQEALCVISGVPGLKGDVTDT 420
Query: 655 ESIALSALPCSHHP 668
E +A L SHHP
Sbjct: 421 EQLAQEMLIISHHP 434
Score = 81.0 bits (191), Expect = 5e-14
Identities = 48/142 (33%), Positives = 77/142 (54%), Gaps = 5/142 (3%)
Query: 726 PDGMSSSAVQAALVWLQDPQLQRVTRDEYFVYLTPDDDIYDKSSVPGNEDN--KEMNLKR 783
PD + + +Q+P L+ VTR+E+ + TP ++YDKS + + + K+ N+KR
Sbjct: 456 PDRVLPQLISTITASVQNPALRLVTREEFAIMQTPAGELYDKSIIQSAQQDSIKKANMKR 515
Query: 784 ESKAYSYXXXXXXXXXXXXXXXXXXXXGKIKETPLSAKQKEAIKAQLAKESAVRKRLSVL 843
E+KAYS+ G +E L++KQKE ++AQL +E+ VR+RL L
Sbjct: 516 ENKAYSFKEQIIELELKEEIKKKK---GIKEEVQLTSKQKEMLQAQLDREAQVRRRLQEL 572
Query: 844 NERLVCAVGLLEAVQRGCPSAL 865
+ L A+GLL+ + PS L
Sbjct: 573 DGELEAALGLLDIILAKNPSGL 594
>U77700-1|AAC51648.1| 1928|Homo sapiens HsGCN1 protein.
Length = 1928
Score = 1478 bits (3663), Expect = 0.0
Identities = 831/1699 (48%), Positives = 1072/1699 (63%), Gaps = 119/1699 (7%)
Query: 874 LYKPQCDLDPSWEDEDLVEATSRVINLLHXXXXXXXXXXXXTKKLNHFTAPGFCYVFPVV 933
L KP+C LD SW E+L A R + LLH +AP F VFP +
Sbjct: 86 LLKPECVLDKSWCQEELSVAVKRAVMLLHTHTITSRVGKGEPGAAP-LSAPAFSLVFPFL 144
Query: 934 KLGLTK--ELSEKDEMTMLNGLAVITHHVSARPHPDD----AELLHPALFPMDEIFRLLI 987
K+ LT+ SE++E M L ++T R P+ + P L P + RLL
Sbjct: 145 KMVLTEMPHHSEEEEEWMAQILQILTVQAQLRASPNTPPGRVDENGPELLPRVAMLRLLT 204
Query: 988 ELIE--STRLCAQAACIVALLEAARCXXXXXXXXXXXXXXXXXXXSESEV--VRDTVLQX 1043
+I S RL A+ + L A+ +S VR+TVL+
Sbjct: 205 WVIGTGSPRLQVLASDTLTTLCASSSGDDGCAFAEQEEVDVLLCALQSPCASVRETVLRG 264
Query: 1044 XXXXXXXXXXXXQDEDYAYSVVKRILIATFDVVEDNKKLAVELWERVPGCEPVSRGALMA 1103
DE ++++R+ + FD E+ +KLA LW + + +
Sbjct: 265 LMELHMVLPAPDTDEKNGLNLLRRLWVVKFDKEEEIRKLAERLWSMMG----LDLQPDLC 320
Query: 1104 DLVLDELQTXXXXXXXXXXXXXXXXXXRGDAPCDVLLQRLQDLYAEKLPLIPAKQDQFGH 1163
L++D++ R ++ RL ++Y EKL P D G
Sbjct: 321 SLLIDDVIYHEAAVRQAGAEALSQAVARYQRQAAEVMGRLMEIYQEKLYRPPPVLDALGR 380
Query: 1164 EV-EPALDMWEXXXXXXXXXXXXXXXXQVGAVPAVMRFFVEWGLADRRDDVRAEMLAAAM 1222
+ E D WE V + +FFV L DR DVR ML AA+
Sbjct: 381 VISESPPDQWEARCGLALALNKLSQYLDSSQVKPLFQFFVPDALNDRHPDVRKCMLDAAL 440
Query: 1223 AIVELHGKDTISSQLPVFERFLDSAPKSGSYDAVREAVVLLVGSLARHLEPDDVRLRPIA 1282
A + HGK+ ++S LPVFE FL +AP SYDAVR++VV+L+GSLA+HL+ D +++PI
Sbjct: 441 ATLNTHGKENVNSLLPVFEEFLKNAPNDASYDAVRQSVVVLMGSLAKHLDKSDPKVKPIV 500
Query: 1283 LRLVAALSTPAQQVPHPHITSLSVAASSGCRPSVQEAVGNCLPHLVTSPALESEIPGIVN 1342
+L+AALSTP+QQ VQE+V +CLP LV PA++ + G++
Sbjct: 501 AKLIAALSTPSQQ--------------------VQESVASCLPPLV--PAIKEDAGGMIQ 538
Query: 1343 KLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKNYKYREGAL 1402
+LM+QLL ++K+ +R+GAAYG+AG+VKGLGILSLKQ ++M LT+AIQ+KKN++ REGAL
Sbjct: 539 RLMQQLLESDKYAERKGAAYGLAGLVKGLGILSLKQQEMMAALTDAIQDKKNFRRREGAL 598
Query: 1403 FGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVL 1462
F FE+LC +LG+LFEPY+VHVLPHLLLC GDG+QYVR AADD A+ +MS LSAHGVKLVL
Sbjct: 599 FAFEMLCTMLGKLFEPYVVHVLPHLLLCFGDGNQYVREAADDCAKAVMSNLSAHGVKLVL 658
Query: 1463 PALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAA 1522
P+LL A+ +++WRTKAGS+ELLGAMAYCAPKQLSSCLP+IVP+L EVL+DSH++VQ +
Sbjct: 659 PSLLAALEEESWRTKAGSVELLGAMAYCAPKQLSSCLPNIVPKLTEVLTDSHVKVQKAGQ 718
Query: 1523 AALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPV 1582
AL+ IGSVIRNPEI AI PVLL L DPS KT CLQTLLDTKFVHFIDAPSLALIMP+
Sbjct: 719 QALRQIGSVIRNPEILAIAPVLLDVLTDPSRKTQKCLQTLLDTKFVHFIDAPSLALIMPI 778
Query: 1583 VQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSAR 1642
VQRAF DRST+TRKMAAQIIGNMYSLTDQKDL PYLP++ PGLK+SLLDPVPEVR+VSA+
Sbjct: 779 VQRAFQDRSTDTRKMAAQIIGNMYSLTDQKDLAPYLPSVTPGLKASLLDPVPEVRTVSAK 838
Query: 1643 ALGAMVKGMGESSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQKLHKIMPGD 1702
ALG MVKGMGES FE+LLPWLM TLT E SSVDRSGAAQGL+EV+AGLGV+KL K+MP
Sbjct: 839 ALGVMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMP-- 896
Query: 1703 TPACNRNKVIPTYIIATAERTDIAPHVKDGYIMMFIYMPGAFTDEFTPYIGQIINPILKA 1762
I+ATA + DIAPHV+DGYIMMF Y+P F D+FTPY+G II ILKA
Sbjct: 897 ------------EIVATASKVDIAPHVRDGYIMMFNYLPITFGDKFTPYVGPIIPCILKA 944
Query: 1763 LADENEYVRETALRAGQRIVNLYAESAIALLLPELEKGLFDDNWRIRYSSVQLLGDLLYR 1822
LADENE+VR+TALRAGQR++++YAE+AIALLLP+LE+GLFDD WRIR+SSVQLLGDLL+
Sbjct: 945 LADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLFH 1004
Query: 1823 ISGVTGKMSTETASEDDNFGTEQSHKAIITALGPERRNRVLAGLYMGRSDVALMVRQAAL 1882
ISGVTGKM+TETASEDDNFGT QS+KAIITALG ERRNRVLAGLYMGRSD L+VRQA+L
Sbjct: 1005 ISGVTGKMTTETASEDDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQASL 1064
Query: 1883 HSY---------DKRQVAARTLGDLV---------------RKLGERV-------LPEIV 1911
H + R++ G L+ R LG+ V LPEI+
Sbjct: 1065 HVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPEII 1124
Query: 1912 PILERGLRSPRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAA 1971
PILE GLRS ++D+RQGVCIGL EI+ STSRDAVL F++ LVPT R ALCDPL EVR AA
Sbjct: 1125 PILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVREAA 1184
Query: 1972 ARTFDSLHATIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLRIMSIKSRAVLPY 2031
A+TF+ LH+TIG++AL+DILP++L+ L D + V++ LDGLKQ +M+IKSR VLPY
Sbjct: 1185 AKTFEQLHSTIGHQALEDILPFLLKQLDDEE--VSEFALDGLKQ----VMAIKSRVVLPY 1238
Query: 2032 LIPVLTXXXXXXVDTRXXXXXXXXXXXXXXRHVPRVLPALLHALEAARATPHEAAELDHC 2091
L+P LT V+TR RH+ +LPA++ AL+ TP E E+ +C
Sbjct: 1239 LVPKLT---TPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQLEMANC 1295
Query: 2092 RDPLLPVTDPPGLRCIIDTLLDTVRSSEGSXXXXXXVLLCAFVAHTRGDLEPHVPQXXXX 2151
+ +L V D G R II+ LL+ RS E ++L + + ++ D H+
Sbjct: 1296 QAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLVSG 1355
Query: 2152 XXXXXXXXXXXXXXMAWEALSALTKTLDAERQIQHVSDVRQAVRYAAADLKGDLLPGFCL 2211
+W+AL+A+TK LDA Q+ + ++ + +R + KG+ +PGFCL
Sbjct: 1356 LIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGFCL 1415
Query: 2212 PKVMWDISGRLWRCYRQLRAIYTSLTGIAPILPLFRESILNGLPEDKENAALMLGEVIKL 2271
PK G+ ILP+ RE +L G PE KE AA LG VI+L
Sbjct: 1416 PK-----------------------KGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRL 1452
Query: 2272 TSPAAIQPSVVHITGPLIRILGDRFNSSVKAAVLETLASLLSKVGVMLKQFLPQLQTTFL 2331
TS ++PSVV ITGPLIRILGDRF+ +VKAA+LETL+ LL+KVG+ LK FLPQLQTTF
Sbjct: 1453 TSADVLRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIALKPFLPQLQTTFT 1512
Query: 2332 KALNDPNRPVRIKAGLALSQLVIIHTRADPLFVEMHNGIKNTDDPAIRETMLQALRSIIS 2391
KAL D NR VR+KA AL +L+ IH + DPLF E+ NGI+ +DP +R+TMLQALR +I
Sbjct: 1513 KALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGVRDTMLQALRFVIQ 1572
Query: 2392 GGGDKLSEQLALSILSTLTSPALLAHPEDPPRGAVGGCLGALLHWLPSAHHDAALQHHVL 2451
G G K+ + +I+S L S +L H ED R + GCLG L +L A LQ +L
Sbjct: 1573 GAGAKVDAVIRKNIVSLLLS--MLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQCLL 1630
Query: 2452 AQSD--DWLLQHGRSCALFVALKETPASIYRDHYEEKIDKTLLASWPATRSRSSVTSMNH 2509
A DW+++HGRS AL VA+ P + Y + + +L+S A R +V+ +
Sbjct: 1631 ADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATADRIPIAVSGVRG 1690
Query: 2510 QSNEVKQMMARASGALGRE 2528
++ + G L R+
Sbjct: 1691 MGFLMRHHIETGGGQLPRK 1709
Score = 49.6 bits (113), Expect = 1e-04
Identities = 23/75 (30%), Positives = 45/75 (60%)
Query: 2531 NPELLRAVLPALVNGTKEKNSYVRANAESSLRTLLRLHSEPDYFQRCVSFLEEGAREALS 2590
+P+ ++ +L AL++ TK+KN+ VRA ++ ++ LL++ + FQ L+ + E L+
Sbjct: 1745 DPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVASLEVLN 1804
Query: 2591 DVVARVLRRPQPDGR 2605
+V R L++ GR
Sbjct: 1805 EVNRRSLKKLAKPGR 1819
>U88836-1|AAD00655.1| 994|Homo sapiens translational activator GCN1
protein.
Length = 994
Score = 828 bits (2049), Expect = 0.0
Identities = 492/1043 (47%), Positives = 646/1043 (61%), Gaps = 117/1043 (11%)
Query: 1641 ARALGAMVKGMGESSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQKLHKIMP 1700
A+ALGAMVKGMGES FE+LLPWLM TLT E SSVDRSGAAQGL+EV+AGLGV+KL K+MP
Sbjct: 1 AKALGAMVKGMGESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMP 60
Query: 1701 GDTPACNRNKVIPTYIIATAERTDIAPHVKDGYIMMFIYMPGAFTDEFTPYIGQIINPIL 1760
I+ATA + DIAPHV+DGYIMM Y+P F D+FTPY+G II IL
Sbjct: 61 E--------------IVATASKVDIAPHVRDGYIMMSNYLPITFGDKFTPYVGPIIPCIL 106
Query: 1761 KALADENEYVRETALRAGQRIVNLYAESAIALLLPELEKGLFDDNWRIRYSSVQLLGDLL 1820
KALADENE+VR+TALRAGQR++++YAE+AIALLLP+LE+GLFDD WRIR+SSVQLLGDLL
Sbjct: 107 KALADENEFVRDTALRAGQRVISMYAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLL 166
Query: 1821 YRISGVTGKMSTETASEDDNFGTEQSHKAIITALGPERRNRVLAGLYMGRSDVALMVRQA 1880
+ ISGVTGKM+TETASEDDNFGT QS+KAIITALG ERRNRVLAGLYMGRSD L+VRQA
Sbjct: 167 FHISGVTGKMTTETASEDDNFGTAQSNKAIITALGVERRNRVLAGLYMGRSDTQLVVRQA 226
Query: 1881 ALHSY---------DKRQVAARTLGDLV---------------RKLGERV-------LPE 1909
+LH + R++ G L+ R LG+ V LPE
Sbjct: 227 SLHVWKIVVSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEKILPE 286
Query: 1910 IVPILERGLRSPRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRL 1969
I+PILE GLRS ++D+RQGVCIGL EI+ STSRDAVL F++ LVPT R ALCDPL EVR
Sbjct: 287 IIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEVRE 346
Query: 1970 AAARTFDSLHATIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLRIMSIKSRAVL 2029
AAA+TF+ LH+TIG++AL+DILP++L+ L D + V++ LDGLKQ +M+IKSR VL
Sbjct: 347 AAAKTFEQLHSTIGHQALEDILPFLLKQLDDEE--VSEFALDGLKQ----VMAIKSRVVL 400
Query: 2030 PYLIPVLTXXXXXXVDTRXXXXXXXXXXXXXXRHVPRVLPALLHALEAARATPHEAAELD 2089
PYL+P LT V+TR RH+ +LPA++ AL+ TP E E+
Sbjct: 401 PYLVPKLT---TPPVNTRVLAFLSSVAGDALTRHLGVILPAVMLALKEKLGTPDEQLEMA 457
Query: 2090 HCRDPLLPVTDPPGLRCIIDTLLDTVRSSEGSXXXXXXVLLCAFVAHTRGDLEPHVPQXX 2149
+C+ +L V D G R II+ LL+ RS E ++L + + ++ D H+
Sbjct: 458 NCQAVILSVEDDTGHRIIIEDLLEATRSPEVGMRQAAAIILNIYCSRSKADYTSHLRSLV 517
Query: 2150 XXXXXXXXXXXXXXXXMAWEALSALTKTLDAERQIQHVSDVRQAVRYAAADLKGDLLPGF 2209
+W+AL+A+TK LDA Q+ + ++ + +R + KG+ +PGF
Sbjct: 518 SGLIRLFNDSSPVVLEESWDALNAITKKLDAGNQLALIEELHKEIRLIGNESKGEHVPGF 577
Query: 2210 CLPKVMWDISGRLWRCYRQLRAIYTSLTGIAPILPLFRESILNGLPEDKENAALMLGEVI 2269
CLPK G+ ILP+ RE +L G PE KE AA LG VI
Sbjct: 578 CLPK-----------------------KGVTSILPVLREGVLTGSPEQKEEAAKALGLVI 614
Query: 2270 KLTSPAAIQPSVVHITGPLIRILGDRFNSSVKAAVLETLASLLSKVGVMLKQFLPQLQTT 2329
+LTS A++PSVV ITGPLIRILGDRF+ +VKAA+LETL+ LL+KVG+ LK FLPQLQTT
Sbjct: 615 RLTSADALRPSVVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIALKPFLPQLQTT 674
Query: 2330 FLKALNDPNRPVRIKAGLALSQLVIIHTRADPLFVEMHNGIKNTDDPAIRETMLQALRSI 2389
F KAL D NR VR+KA AL +L+ IH + DPLF E+ NGI+ +DP +R+TMLQALR +
Sbjct: 675 FTKALQDSNRGVRLKAADALGKLISIHIKVDPLFTELLNGIRAMEDPGVRDTMLQALRFV 734
Query: 2390 ISGGGDKLSEQLALSILSTLTSPALLAHPEDPPRGAVGGCLGALLHWLPSAHHDAALQHH 2449
I G G K+ + +I+S L S +L H ED R + GCLG L +L A LQ
Sbjct: 735 IQGAGAKVDAVIRKNIVSLLLS--MLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQC 792
Query: 2450 VLAQSD--DWLLQHGRSCALFVALKETPASIYRDHYEEKIDKTLLASWPATRSRSSVTSM 2507
+LA DW+++HGR+ AL VA+ P + Y + + +L+S A R +V+ +
Sbjct: 793 LLADVSGIDWMVRHGRTLALSVAVNVAPGRLCAGRYSSDVQEMILSSATADRIPIAVSGV 852
Query: 2508 --------NHQSNEVKQMMARASGALGREADNPEL-LRAV------------LPAL---- 2542
+H Q+ A+ S + NP +R V LP L
Sbjct: 853 RGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKDPLPPLDPQA 912
Query: 2543 --------VNGTKEKNSYVRANAESSLRTLLRLHSEPDYFQRCVSFLEEGAREALSDVVA 2594
++ TK+KN+ VRA ++ ++ LL++ + FQ L+ + E L++V
Sbjct: 913 IKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVASLEVLNEVNR 972
Query: 2595 RVLRR--PQPDGRDEDLDCTLIT 2615
R L++ Q D E +D T++T
Sbjct: 973 RSLKKLASQADS-TEQVDDTILT 994
Score = 77.8 bits (183), Expect = 5e-13
Identities = 91/377 (24%), Positives = 155/377 (41%), Gaps = 30/377 (7%)
Query: 1334 ESEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKK 1393
ES ++ LM+ L + DR GAA G+A V+ GLG+ L++L M ++ +
Sbjct: 13 ESCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKL--MPEIVATASKVD 70
Query: 1394 NYKY-REGALFGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSR 1452
+ R+G + L G F PY+ ++P +L L D +++VR A + ++S
Sbjct: 71 IAPHVRDGYIMMSNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISM 130
Query: 1453 LSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSD 1512
+ + L+LP L + DD WR + S++LLG + + +S + D
Sbjct: 131 YAETAIALLLPQLEQGLFDDLWRIRFSSVQLLGDLLF----HISGVTGKMTTETAS--ED 184
Query: 1513 SHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFID 1572
+ S A + +G RN VL S+ Q L + +
Sbjct: 185 DNFGTAQSNKAIITALGVERRN-------RVLAGLYMGRSDTQLVVRQASLHVWKIVVSN 237
Query: 1573 AP-SLALIMPVVQRAFL----DRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKS 1627
P +L I+P + L + R +AA+ +G++ +K LP IIP L+
Sbjct: 238 TPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGDLVRKLGEK----ILPEIIPILEE 293
Query: 1628 SLLDPVPEVRSVSARALGAMVKGMGESSF----EELLPWLMHTLTSETSSVDRSGAAQGL 1683
L + R L ++K + E L+P L V R AA+
Sbjct: 294 GLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPTARKALCDPLEEV-REAAAKTF 352
Query: 1684 SEVVAGLGVQKLHKIMP 1700
++ + +G Q L I+P
Sbjct: 353 EQLHSTIGHQALEDILP 369
Score = 49.6 bits (113), Expect = 1e-04
Identities = 42/184 (22%), Positives = 86/184 (46%), Gaps = 13/184 (7%)
Query: 1511 SDSHLRVQLSAAAALKVIGSVIRNPE-IQAIVPVLLQAL-----QDPSNKTSACLQTLLD 1564
SD+ L V+ ++ K++ V P ++ I+P L L ++K + +TL D
Sbjct: 217 SDTQLVVRQASLHVWKIV--VSNTPRTLREILPTLFGLLLGFLASTCADKRTIAARTLGD 274
Query: 1565 TKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPG 1624
V + L I+P+++ + ++ R+ + + T + + + +++P
Sbjct: 275 --LVRKLGEKILPEIIPILEEGLRSQKSDERQGVCIGLSEIMKSTSRDAVLYFSESLVPT 332
Query: 1625 LKSSLLDPVPEVRSVSARALGAMVKGMGESSFEELLPWLMHTLTSETSSVDRSGAAQGLS 1684
+ +L DP+ EVR +A+ + +G + E++LP+L+ L E S A GL
Sbjct: 333 ARKALCDPLEEVREAAAKTFEQLHSTIGHQALEDILPFLLKQLDDEEVS---EFALDGLK 389
Query: 1685 EVVA 1688
+V+A
Sbjct: 390 QVMA 393
Score = 36.7 bits (81), Expect = 1.1
Identities = 46/214 (21%), Positives = 97/214 (45%), Gaps = 25/214 (11%)
Query: 1497 SCLPSIVPRLIEVLSDSHLRVQLSAAA-ALKVIGSVIRNPEIQAIVPVLLQALQDPSNKT 1555
SC ++P L+E L+ V S AA L + + + +++ ++P ++
Sbjct: 14 SCFEDLLPWLMETLTYEQSSVDRSGAAQGLAEVMAGLGVEKLEKLMPEIVATASKVDIAP 73
Query: 1556 SACLQTLLDTKF--VHFID--APSLALIMPVVQRAFLDRS---TETRKMAAQIIGNMYSL 1608
++ + + + F D P + I+P + +A D + +T A Q + +MY+
Sbjct: 74 HVRDGYIMMSNYLPITFGDKFTPYVGPIIPCILKALADENEFVRDTALRAGQRVISMYAE 133
Query: 1609 TDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSFEELLPWLMHTLT 1668
T + ++P L+ L D + +R S + LG ++ F + + +T
Sbjct: 134 T-------AIALLLPQLEQGLFDDLWRIRFSSVQLLGDLL-------FH--ISGVTGKMT 177
Query: 1669 SETSSVDRS-GAAQGLSEVVAGLGVQKLHKIMPG 1701
+ET+S D + G AQ ++ LGV++ ++++ G
Sbjct: 178 TETASEDDNFGTAQSNKAIITALGVERRNRVLAG 211
>U88837-1|AAD00656.1| 356|Homo sapiens translational activator GCN1
protein.
Length = 356
Score = 138 bits (334), Expect = 2e-31
Identities = 88/310 (28%), Positives = 156/310 (50%), Gaps = 7/310 (2%)
Query: 3 DTEVLKKLKDIPFKIQTASLKGRLEVVNEIREILSSPGITEPAVKFVCRVLALTLHRYRD 62
DT+V + LK K+ TAS+K R E+++E+ + ++ + E AVK +C++ LTLHRYRD
Sbjct: 1 DTQVSETLKRFAGKVTTASVKERREILSELGKCVAGKDLPEGAVKGLCKLFCLTLHRYRD 60
Query: 63 TTSQSYIKSLVAFLATEHTEWAFKNLSPVLLEISEQLXXXXXXXXXXXXGLFALRWSSVL 122
S+ +++ + LA E KNL L L AL W+ +L
Sbjct: 61 AASRRALQAAIQQLAEAQPEATAKNLLHSLQSSGIGSKAGVPSKSSGSAALLALTWTCLL 120
Query: 123 VESS-PKSLEHEVDL-NSLILAQANLLATVCAYGDKKKNKKAYSVLHAVWSKIGKEKVLK 180
V P + + D+ N L+ Q LL V K A L +W K V +
Sbjct: 121 VRIVFPSRAKRQGDIWNKLVEVQCLLLLEVLGGSHKHAVDGAVKKLTKLW-KENPGLVEQ 179
Query: 181 WVETLLA-QPGDSGPHISVTFSALCAHYKDIGDESIITLHKAKMLENFTKSLISVKSRPN 239
++ +L+ +P + + C +K++ +++ HK+ +L+ + K+++ K +P
Sbjct: 180 YLSAILSLEPNQNYAGMLGLLVQFCTSHKEM---DVVSQHKSALLDFYMKNILMSKVKPP 236
Query: 240 ANYIKGCSDLLHLLSESDIQDTLLPALHKAMLRSPETIVQAVGEVVANLNIYLDGVAVDI 299
+ C+ LL LS S+ +D +LP + K++LRSPE +++ + ++A++ + L A+DI
Sbjct: 237 KYLLDSCAPLLRYLSHSEFKDLILPTIQKSLLRSPENVIETISSLLASVTLDLSQYAMDI 296
Query: 300 GKSLIVNLHS 309
K L +L S
Sbjct: 297 VKGLAGHLKS 306
>BC021129-1|AAH21129.1| 299|Homo sapiens Unknown (protein for
IMAGE:4622972) protein.
Length = 299
Score = 125 bits (301), Expect = 2e-27
Identities = 96/302 (31%), Positives = 150/302 (49%), Gaps = 40/302 (13%)
Query: 2351 QLVIIHTRADPLFVEMHNGIKNTDDPAIRETMLQALRSIISGGGDKLSEQLALSILSTLT 2410
+L+ IH + DPLF E+ NGI+ +DP +R+TMLQALR +I G G K+ + +I+S L
Sbjct: 1 KLISIHIKVDPLFTELLNGIRAMEDPGVRDTMLQALRFVIQGAGAKVDAVIRKNIVSLLL 60
Query: 2411 SPALLAHPEDPPRGAVGGCLGALLHWLPSAHHDAALQHHVLAQSD--DWLLQHGRSCALF 2468
S +L H ED R + GCLG L +L A LQ +LA DW+++HGRS AL
Sbjct: 61 S--MLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQCLLADVSGIDWMVRHGRSLALS 118
Query: 2469 VALKETPASIYRDHYEEKIDKTLLASWPATRSRSSVTSM--------NHQSNEVKQMMAR 2520
VA+ P + Y + + +L+S A R +V+ + +H Q+ A+
Sbjct: 119 VAVNVAPGRLCAGRYSSDVQEMILSSATADRIPIAVSGVRGMGFLMRHHIETGGGQLPAK 178
Query: 2521 ASGALGREADNPEL-LRAV------------LPAL------------VNGTKEKNSYVRA 2555
S + NP +R V LP L ++ TK+KN+ VRA
Sbjct: 179 LSSLFVKCLQNPSSDIRLVAEKMIWWANKDPLPPLDPQAIKPILKALLDNTKDKNTVVRA 238
Query: 2556 NAESSLRTLLRLHSEPDYFQRCVSFLEEGAREALSDVVARVLRR--PQPDGRDEDLDCTL 2613
++ ++ LL++ + FQ L+ + E L++V R L++ Q D E +D T+
Sbjct: 239 YSDQAIVNLLKMRQGEEVFQSLSKILDVASLEVLNEVNRRSLKKLASQADS-TEQVDDTI 297
Query: 2614 IT 2615
+T
Sbjct: 298 LT 299
>BC032335-1|AAH32335.1| 284|Homo sapiens Unknown (protein for
IMAGE:5181594) protein.
Length = 284
Score = 106 bits (255), Expect = 9e-22
Identities = 88/285 (30%), Positives = 138/285 (48%), Gaps = 40/285 (14%)
Query: 2368 NGIKNTDDPAIRETMLQALRSIISGGGDKLSEQLALSILSTLTSPALLAHPEDPPRGAVG 2427
NGI+ +DP +R+TMLQALR +I G G K+ + +I+S L S +L H ED R +
Sbjct: 3 NGIRAMEDPGVRDTMLQALRFVIQGAGAKVDAVIRKNIVSLLLS--MLGHDEDNTRISSA 60
Query: 2428 GCLGALLHWLPSAHHDAALQHHVLAQSD--DWLLQHGRSCALFVALKETPASIYRDHYEE 2485
GCLG L +L A LQ +LA DW+++HGRS AL VA+ P + Y
Sbjct: 61 GCLGELCAFLTEEELSAVLQQCLLADVSGIDWMVRHGRSLALSVAVNVAPGRLCAGRYSS 120
Query: 2486 KIDKTLLASWPATRSRSSVTSM--------NHQSNEVKQMMARASGALGREADNPEL-LR 2536
+ + +L+S A R +V+ + +H Q+ A+ S + NP +R
Sbjct: 121 DVQEMILSSATADRIPIAVSGVRGMGFLMRHHIETGGGQLPAKLSSLFVKCLQNPSSDIR 180
Query: 2537 AV------------LPAL------------VNGTKEKNSYVRANAESSLRTLLRLHSEPD 2572
V LP L ++ TK+KN+ VRA ++ ++ LL++ +
Sbjct: 181 LVAEKMIWWANKDPLPPLDPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEE 240
Query: 2573 YFQRCVSFLEEGAREALSDVVARVLRR--PQPDGRDEDLDCTLIT 2615
FQ L+ + E L++V R L++ Q D E +D T++T
Sbjct: 241 VFQSLSKILDVASLEVLNEVNRRSLKKLASQADS-TEQVDDTILT 284
>BC064346-1|AAH64346.1| 247|Homo sapiens GCN1L1 protein protein.
Length = 247
Score = 70.9 bits (166), Expect = 6e-11
Identities = 71/249 (28%), Positives = 114/249 (45%), Gaps = 40/249 (16%)
Query: 2404 SILSTLTSPALLAHPEDPPRGAVGGCLGALLHWLPSAHHDAALQHHVLAQSD--DWLLQH 2461
+I+S L S +L H ED R + GCLG L +L A LQ +LA DW+++H
Sbjct: 2 NIVSLLLS--MLGHDEDNTRISSAGCLGELCAFLTEEELSAVLQQCLLADVSGIDWMVRH 59
Query: 2462 GRSCALFVALKETPASIYRDHYEEKIDKTLLASWPATRSRSSVTSM--------NHQSNE 2513
GRS AL VA+ P + Y + + +L+S A R +V+ + +H
Sbjct: 60 GRSLALSVAVNVAPGRLCAGRYSSDVQEMILSSATADRIPIAVSGVRGMGFLMRHHIETG 119
Query: 2514 VKQMMARASGALGREADNPEL-LRAV------------LPAL------------VNGTKE 2548
Q+ A+ S + NP +R V LP L ++ TK+
Sbjct: 120 GGQLPAKLSSLFVKCLQNPSSDIRLVAEKMIWWANKDPLPPLDPQAIKPILKALLDNTKD 179
Query: 2549 KNSYVRANAESSLRTLLRLHSEPDYFQRCVSFLEEGAREALSDVVARVLRR--PQPDGRD 2606
KN+ VRA ++ ++ LL++ + FQ L+ + E L++V R L++ Q D
Sbjct: 180 KNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVASLEVLNEVNRRSLKKLASQADS-T 238
Query: 2607 EDLDCTLIT 2615
E +D T++T
Sbjct: 239 EQVDDTILT 247
>BC068491-1|AAH68491.1| 873|Homo sapiens KIAA1622 protein.
Length = 873
Score = 52.4 bits (120), Expect = 2e-05
Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 8/181 (4%)
Query: 1499 LPSIVPRLIEVLSDSHLRVQLSAAAALKVI---GSVIRNPEIQAIVPVLLQALQDPSNKT 1555
L ++P++ E L + + +QL+AA + I SV + + + V+L L+
Sbjct: 90 LRRVLPKVREALHVAGVEMQLTAAMSFLTILQDESVSIHAYTHSFLQVILLHLEHRDTGV 149
Query: 1556 S-ACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDL 1614
S A L+TLL V + ++ P+V +A L ++ ++R ++ +I+G LT++ D
Sbjct: 150 SNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQSRLVSCKILGK---LTNKFDA 206
Query: 1615 TPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMG-ESSFEELLPWLMHTLTSETSS 1673
I+P +KS D EVRS R L + +G+G E + +LP L+ E SS
Sbjct: 207 HTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSS 266
Query: 1674 V 1674
V
Sbjct: 267 V 267
>AB046842-1|BAB13448.1| 892|Homo sapiens KIAA1622 protein protein.
Length = 892
Score = 52.4 bits (120), Expect = 2e-05
Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 8/181 (4%)
Query: 1499 LPSIVPRLIEVLSDSHLRVQLSAAAALKVI---GSVIRNPEIQAIVPVLLQALQDPSNKT 1555
L ++P++ E L + + +QL+AA + I SV + + + V+L L+
Sbjct: 109 LRRVLPKVREALHVAGVEMQLTAAMSFLTILQDESVSIHAYTHSFLQVILLHLEHRDTGV 168
Query: 1556 S-ACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDL 1614
S A L+TLL V + ++ P+V +A L ++ ++R ++ +I+G LT++ D
Sbjct: 169 SNAWLETLLSVIEVLPKETLRHEILNPLVSKAQLSQTVQSRLVSCKILGK---LTNKFDA 225
Query: 1615 TPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMG-ESSFEELLPWLMHTLTSETSS 1673
I+P +KS D EVRS R L + +G+G E + +LP L+ E SS
Sbjct: 226 HTIKREILPLVKSLCQDVEYEVRSCMCRQLENIAQGIGTELTKSVVLPELIELSRDEGSS 285
Query: 1674 V 1674
V
Sbjct: 286 V 286
>BC046177-1|AAH46177.1| 189|Homo sapiens GCN1L1 protein protein.
Length = 189
Score = 50.4 bits (115), Expect = 8e-05
Identities = 27/87 (31%), Positives = 52/87 (59%), Gaps = 3/87 (3%)
Query: 2531 NPELLRAVLPALVNGTKEKNSYVRANAESSLRTLLRLHSEPDYFQRCVSFLEEGAREALS 2590
+P+ ++ +L AL++ TK+KN+ VRA ++ ++ LL++ + FQ L+ + E L+
Sbjct: 104 DPQAIKPILKALLDNTKDKNTVVRAYSDQAIVNLLKMRQGEEVFQSLSKILDVASLEVLN 163
Query: 2591 DVVARVLRR--PQPDGRDEDLDCTLIT 2615
+V R L++ Q D E +D T++T
Sbjct: 164 EVNRRSLKKLASQADS-TEQVDDTILT 189
>AL354661-2|CAH73240.1| 1839|Homo sapiens KIAA0368 protein.
Length = 1839
Score = 48.8 bits (111), Expect = 3e-04
Identities = 67/284 (23%), Positives = 112/284 (39%), Gaps = 15/284 (5%)
Query: 1256 VREAVVLLVGSLARHLEPD-DVR--LRPIALRLVAALSTPAQQVPHPHITSLSVAASSGC 1312
VR+A + + SL R L +V+ L+ I V+ LS + L + G
Sbjct: 952 VRQAACIWLLSLVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGN 1011
Query: 1313 RPSVQEAVGNCLPHLVTSPALESEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLG 1372
QE V + L+T ++ E+ G ++ Q K D +G + K L
Sbjct: 1012 EQDQQELVSTLVETLMTGKRVKHEVSG--ETVVFQGGALGKTPDGQGLS-----TYKELC 1064
Query: 1373 ILS--LKQLDIMGKLTEAIQEKKNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLC 1430
L+ L Q D++ K + R+GA FGF ++ G P++ ++P L
Sbjct: 1065 SLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRY 1124
Query: 1431 LGDGSQYVRTAADDTARLIMSRLSA--HGVKLVLPALLNAVNDDNWRTKAGSIELLGAMA 1488
D + +R A +++ S +K +L L+ + + WR + S L +
Sbjct: 1125 QFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLL 1184
Query: 1489 YCAP-KQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSV 1531
P + LP I L V D V+ +A ALK + V
Sbjct: 1185 RGRPLDDIIDKLPEIWETLFRVQDDIKESVRKAAELALKTLSKV 1228
Score = 35.9 bits (79), Expect = 2.0
Identities = 53/206 (25%), Positives = 87/206 (42%), Gaps = 19/206 (9%)
Query: 1458 VKLVLPALLN-AVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLR 1516
+ +LP LL+ + +A SI L ++ A L P ++P L+E LS +
Sbjct: 1245 IAALLPCLLDKGMMSTVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQ 1304
Query: 1517 VQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSL 1576
V L + E A+ L A K+S ++T+ + ++D L
Sbjct: 1305 V-------LNYLSLRATEQEKAAMDSARLSAA-----KSSPMMETI--NMCLQYLDVSVL 1350
Query: 1577 ALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQ--KDLTPYLPNIIPGLKSSLLDPVP 1634
++P + L RS + SLT Q +DLTPY ++ L S L D
Sbjct: 1351 GELVP--RLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNS 1408
Query: 1635 EVRSVSARALGAMVKGMGESSFEELL 1660
++ A A+G +V+ +SS E+LL
Sbjct: 1409 VIQKSCAFAMGHLVRTSRDSSTEKLL 1434
Score = 34.7 bits (76), Expect = 4.5
Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Query: 1604 NMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMV--KGMGESSFEELLP 1661
N+ + + L P+LP ++P L DP +R A+V K M + +E+L
Sbjct: 1100 NVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQ 1159
Query: 1662 WLMHTLTSETSSVDRSGAAQGLSEVVAG 1689
L+ LTS V R + L++++ G
Sbjct: 1160 DLVKNLTSNMWRV-RESSCLALNDLLRG 1186
Score = 33.9 bits (74), Expect = 7.9
Identities = 17/76 (22%), Positives = 36/76 (47%)
Query: 1722 RTDIAPHVKDGYIMMFIYMPGAFTDEFTPYIGQIINPILKALADENEYVRETALRAGQRI 1781
R+ + K G + + + + TPY G++++ +L L D N ++++ A +
Sbjct: 1362 RSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHL 1421
Query: 1782 VNLYAESAIALLLPEL 1797
V +S+ LL +L
Sbjct: 1422 VRTSRDSSTEKLLQKL 1437
>AL159168-1|CAH73465.1| 1839|Homo sapiens KIAA0368 protein.
Length = 1839
Score = 48.8 bits (111), Expect = 3e-04
Identities = 67/284 (23%), Positives = 112/284 (39%), Gaps = 15/284 (5%)
Query: 1256 VREAVVLLVGSLARHLEPD-DVR--LRPIALRLVAALSTPAQQVPHPHITSLSVAASSGC 1312
VR+A + + SL R L +V+ L+ I V+ LS + L + G
Sbjct: 952 VRQAACIWLLSLVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGN 1011
Query: 1313 RPSVQEAVGNCLPHLVTSPALESEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLG 1372
QE V + L+T ++ E+ G ++ Q K D +G + K L
Sbjct: 1012 EQDQQELVSTLVETLMTGKRVKHEVSG--ETVVFQGGALGKTPDGQGLS-----TYKELC 1064
Query: 1373 ILS--LKQLDIMGKLTEAIQEKKNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLC 1430
L+ L Q D++ K + R+GA FGF ++ G P++ ++P L
Sbjct: 1065 SLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRY 1124
Query: 1431 LGDGSQYVRTAADDTARLIMSRLSA--HGVKLVLPALLNAVNDDNWRTKAGSIELLGAMA 1488
D + +R A +++ S +K +L L+ + + WR + S L +
Sbjct: 1125 QFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLL 1184
Query: 1489 YCAP-KQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSV 1531
P + LP I L V D V+ +A ALK + V
Sbjct: 1185 RGRPLDDIIDKLPEIWETLFRVQDDIKESVRKAAELALKTLSKV 1228
Score = 35.9 bits (79), Expect = 2.0
Identities = 53/206 (25%), Positives = 87/206 (42%), Gaps = 19/206 (9%)
Query: 1458 VKLVLPALLN-AVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLR 1516
+ +LP LL+ + +A SI L ++ A L P ++P L+E LS +
Sbjct: 1245 IAALLPCLLDKGMMSTVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQ 1304
Query: 1517 VQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSL 1576
V L + E A+ L A K+S ++T+ + ++D L
Sbjct: 1305 V-------LNYLSLRATEQEKAAMDSARLSAA-----KSSPMMETI--NMCLQYLDVSVL 1350
Query: 1577 ALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQ--KDLTPYLPNIIPGLKSSLLDPVP 1634
++P + L RS + SLT Q +DLTPY ++ L S L D
Sbjct: 1351 GELVP--RLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNS 1408
Query: 1635 EVRSVSARALGAMVKGMGESSFEELL 1660
++ A A+G +V+ +SS E+LL
Sbjct: 1409 VIQKSCAFAMGHLVRTSRDSSTEKLL 1434
Score = 34.7 bits (76), Expect = 4.5
Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Query: 1604 NMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMV--KGMGESSFEELLP 1661
N+ + + L P+LP ++P L DP +R A+V K M + +E+L
Sbjct: 1100 NVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQ 1159
Query: 1662 WLMHTLTSETSSVDRSGAAQGLSEVVAG 1689
L+ LTS V R + L++++ G
Sbjct: 1160 DLVKNLTSNMWRV-RESSCLALNDLLRG 1186
Score = 33.9 bits (74), Expect = 7.9
Identities = 17/76 (22%), Positives = 36/76 (47%)
Query: 1722 RTDIAPHVKDGYIMMFIYMPGAFTDEFTPYIGQIINPILKALADENEYVRETALRAGQRI 1781
R+ + K G + + + + TPY G++++ +L L D N ++++ A +
Sbjct: 1362 RSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHL 1421
Query: 1782 VNLYAESAIALLLPEL 1797
V +S+ LL +L
Sbjct: 1422 VRTSRDSSTEKLLQKL 1437
>AB002366-1|BAA20823.1| 1441|Homo sapiens KIAA0368 protein.
Length = 1441
Score = 48.8 bits (111), Expect = 3e-04
Identities = 67/284 (23%), Positives = 112/284 (39%), Gaps = 15/284 (5%)
Query: 1256 VREAVVLLVGSLARHLEPD-DVR--LRPIALRLVAALSTPAQQVPHPHITSLSVAASSGC 1312
VR+A + + SL R L +V+ L+ I V+ LS + L + G
Sbjct: 554 VRQAACIWLLSLVRKLSTHKEVKSHLKEIQSAFVSVLSENDELSQDVASKGLGLVYELGN 613
Query: 1313 RPSVQEAVGNCLPHLVTSPALESEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLG 1372
QE V + L+T ++ E+ G ++ Q K D +G + K L
Sbjct: 614 EQDQQELVSTLVETLMTGKRVKHEVSG--ETVVFQGGALGKTPDGQGLS-----TYKELC 666
Query: 1373 ILS--LKQLDIMGKLTEAIQEKKNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLC 1430
L+ L Q D++ K + R+GA FGF ++ G P++ ++P L
Sbjct: 667 SLASDLSQPDLVYKFMNLANHHAMWNSRKGAAFGFNVIATRAGEQLAPFLPQLVPRLYRY 726
Query: 1431 LGDGSQYVRTAADDTARLIMSRLSA--HGVKLVLPALLNAVNDDNWRTKAGSIELLGAMA 1488
D + +R A +++ S +K +L L+ + + WR + S L +
Sbjct: 727 QFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQDLVKNLTSNMWRVRESSCLALNDLL 786
Query: 1489 YCAP-KQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSV 1531
P + LP I L V D V+ +A ALK + V
Sbjct: 787 RGRPLDDIIDKLPEIWETLFRVQDDIKESVRKAAELALKTLSKV 830
Score = 35.9 bits (79), Expect = 2.0
Identities = 53/206 (25%), Positives = 87/206 (42%), Gaps = 19/206 (9%)
Query: 1458 VKLVLPALLN-AVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLR 1516
+ +LP LL+ + +A SI L ++ A L P ++P L+E LS +
Sbjct: 847 IAALLPCLLDKGMMSTVTEVRALSINTLVKISKSAGAMLKPHAPKLIPALLESLSVLEPQ 906
Query: 1517 VQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSL 1576
V L + E A+ L A K+S ++T+ + ++D L
Sbjct: 907 V-------LNYLSLRATEQEKAAMDSARLSAA-----KSSPMMETI--NMCLQYLDVSVL 952
Query: 1577 ALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQ--KDLTPYLPNIIPGLKSSLLDPVP 1634
++P + L RS + SLT Q +DLTPY ++ L S L D
Sbjct: 953 GELVP--RLCELIRSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNS 1010
Query: 1635 EVRSVSARALGAMVKGMGESSFEELL 1660
++ A A+G +V+ +SS E+LL
Sbjct: 1011 VIQKSCAFAMGHLVRTSRDSSTEKLL 1036
Score = 34.7 bits (76), Expect = 4.5
Identities = 24/88 (27%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Query: 1604 NMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMV--KGMGESSFEELLP 1661
N+ + + L P+LP ++P L DP +R A+V K M + +E+L
Sbjct: 702 NVIATRAGEQLAPFLPQLVPRLYRYQFDPNLGIRQAMTSIWNALVTDKSMVDKYLKEILQ 761
Query: 1662 WLMHTLTSETSSVDRSGAAQGLSEVVAG 1689
L+ LTS V R + L++++ G
Sbjct: 762 DLVKNLTSNMWRV-RESSCLALNDLLRG 788
Score = 33.9 bits (74), Expect = 7.9
Identities = 17/76 (22%), Positives = 36/76 (47%)
Query: 1722 RTDIAPHVKDGYIMMFIYMPGAFTDEFTPYIGQIINPILKALADENEYVRETALRAGQRI 1781
R+ + K G + + + + TPY G++++ +L L D N ++++ A +
Sbjct: 964 RSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHL 1023
Query: 1782 VNLYAESAIALLLPEL 1797
V +S+ LL +L
Sbjct: 1024 VRTSRDSSTEKLLQKL 1039
>BC112201-1|AAI12202.1| 1849|Homo sapiens BTAF1 RNA polymerase II,
B-TFIID transcription factor-associated, 170kDa protein.
Length = 1849
Score = 48.0 bits (109), Expect = 5e-04
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 1438 VRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQ--L 1495
VR T +++ ++ GV + LL + + W + G LLG A +Q +
Sbjct: 367 VRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGG--LLGIKYALAVRQDVI 424
Query: 1496 SSCLPSIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVI--RNPEIQAIVPVLLQALQDPS 1552
++ LP ++ R+IE L D V+ AAA+L V+ S++ + ++ I+ L AL +
Sbjct: 425 NTLLPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQTQKVPFIINTLWDALLELD 484
Query: 1553 NKTSA--CLQTLLDTKFVH-----FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNM 1605
+ T++ + TLL + + SL +++P V + R+ A + + +
Sbjct: 485 DLTASTNSIMTLLSSLLTYPQVQQCSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTL 544
Query: 1606 YSLTDQKD---LTPYLPNII 1622
S DQ L P LP+++
Sbjct: 545 LSTQDQNSSSWLIPILPDML 564
Score = 34.7 bits (76), Expect = 4.5
Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 17/171 (9%)
Query: 1405 FELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPA 1464
FE + P +V LPHL +CL S VR A ++ + + + L
Sbjct: 1089 FETAAASMDSELHPLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEK 1148
Query: 1465 LLNAVN--DDNWRTKAGSIELLGAMAYCAPKQLS-SCLPSIVPRLIEVLSDSHLRVQLSA 1521
+L + DD+ + + G+IE L C +QL +P IV ++ VL +
Sbjct: 1149 VLPWLGAIDDSVK-QEGAIEALA----CVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVR 1203
Query: 1522 AAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFID 1572
A + ++IR ++A +P DP N ++ +Q L K HF++
Sbjct: 1204 FMATQCFATLIRLMPLEAGIP-------DPPNMSAELIQ--LKAKERHFLE 1245
>BC030273-1|AAH30273.1| 560|Homo sapiens Unknown (protein for
IMAGE:4424028) protein.
Length = 560
Score = 48.0 bits (109), Expect = 5e-04
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 1438 VRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQ--L 1495
VR T +++ ++ GV + LL + + W + G LLG A +Q +
Sbjct: 37 VRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGG--LLGIKYALAVRQDVI 94
Query: 1496 SSCLPSIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVI--RNPEIQAIVPVLLQALQDPS 1552
++ LP ++ R+IE L D V+ AAA+L V+ S++ + ++ I+ L AL +
Sbjct: 95 NTLLPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQTQKVPFIINTLWDALLELD 154
Query: 1553 NKTSA--CLQTLLDTKFVH-----FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNM 1605
+ T++ + TLL + + SL +++P V + R+ A + + +
Sbjct: 155 DLTASTNSIMTLLSSLLTYPQVQQCSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTL 214
Query: 1606 YSLTDQKD---LTPYLPNII 1622
S DQ L P LP+++
Sbjct: 215 LSTQDQNSSSWLIPILPDML 234
>AL365398-1|CAI14103.1| 1849|Homo sapiens BTAF1 RNA polymerase II,
B-TFIID transcription factor-associated, 170kDa (Mot1
protein.
Length = 1849
Score = 48.0 bits (109), Expect = 5e-04
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 1438 VRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQ--L 1495
VR T +++ ++ GV + LL + + W + G LLG A +Q +
Sbjct: 367 VRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGG--LLGIKYALAVRQDVI 424
Query: 1496 SSCLPSIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVI--RNPEIQAIVPVLLQALQDPS 1552
++ LP ++ R+IE L D V+ AAA+L V+ S++ + ++ I+ L AL +
Sbjct: 425 NTLLPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQTQKVPFIINTLWDALLELD 484
Query: 1553 NKTSA--CLQTLLDTKFVH-----FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNM 1605
+ T++ + TLL + + SL +++P V + R+ A + + +
Sbjct: 485 DLTASTNSIMTLLSSLLTYPQVQQCSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTL 544
Query: 1606 YSLTDQKD---LTPYLPNII 1622
S DQ L P LP+++
Sbjct: 545 LSTQDQNSSSWLIPILPDML 564
Score = 34.7 bits (76), Expect = 4.5
Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 17/171 (9%)
Query: 1405 FELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPA 1464
FE + P +V LPHL +CL S VR A ++ + + + L
Sbjct: 1089 FETAAASMDSELHPLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEK 1148
Query: 1465 LLNAVN--DDNWRTKAGSIELLGAMAYCAPKQLS-SCLPSIVPRLIEVLSDSHLRVQLSA 1521
+L + DD+ + + G+IE L C +QL +P IV ++ VL +
Sbjct: 1149 VLPWLGAIDDSVK-QEGAIEALA----CVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVR 1203
Query: 1522 AAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFID 1572
A + ++IR ++A +P DP N ++ +Q L K HF++
Sbjct: 1204 FMATQCFATLIRLMPLEAGIP-------DPPNMSAELIQ--LKAKERHFLE 1245
>AL359198-2|CAH73478.1| 1849|Homo sapiens BTAF1 RNA polymerase II,
B-TFIID transcription factor-associated, 170kDa (Mot1
protein.
Length = 1849
Score = 48.0 bits (109), Expect = 5e-04
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 1438 VRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQ--L 1495
VR T +++ ++ GV + LL + + W + G LLG A +Q +
Sbjct: 367 VRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGG--LLGIKYALAVRQDVI 424
Query: 1496 SSCLPSIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVI--RNPEIQAIVPVLLQALQDPS 1552
++ LP ++ R+IE L D V+ AAA+L V+ S++ + ++ I+ L AL +
Sbjct: 425 NTLLPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQTQKVPFIINTLWDALLELD 484
Query: 1553 NKTSA--CLQTLLDTKFVH-----FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNM 1605
+ T++ + TLL + + SL +++P V + R+ A + + +
Sbjct: 485 DLTASTNSIMTLLSSLLTYPQVQQCSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTL 544
Query: 1606 YSLTDQKD---LTPYLPNII 1622
S DQ L P LP+++
Sbjct: 545 LSTQDQNSSSWLIPILPDML 564
Score = 34.7 bits (76), Expect = 4.5
Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 17/171 (9%)
Query: 1405 FELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPA 1464
FE + P +V LPHL +CL S VR A ++ + + + L
Sbjct: 1089 FETAAASMDSELHPLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEK 1148
Query: 1465 LLNAVN--DDNWRTKAGSIELLGAMAYCAPKQLS-SCLPSIVPRLIEVLSDSHLRVQLSA 1521
+L + DD+ + + G+IE L C +QL +P IV ++ VL +
Sbjct: 1149 VLPWLGAIDDSVK-QEGAIEALA----CVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVR 1203
Query: 1522 AAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFID 1572
A + ++IR ++A +P DP N ++ +Q L K HF++
Sbjct: 1204 FMATQCFATLIRLMPLEAGIP-------DPPNMSAELIQ--LKAKERHFLE 1245
>AJ001017-1|CAA04475.1| 1849|Homo sapiens TBP associated factor
protein.
Length = 1849
Score = 48.0 bits (109), Expect = 5e-04
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 1438 VRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQ--L 1495
VR T +++ ++ GV + LL + + W + G LLG A +Q +
Sbjct: 367 VRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGG--LLGIKYALAVRQDVI 424
Query: 1496 SSCLPSIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVI--RNPEIQAIVPVLLQALQDPS 1552
++ LP ++ R+IE L D V+ AAA+L V+ S++ + ++ I+ L AL +
Sbjct: 425 NTLLPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQTQKVPFIINTLWDALLELD 484
Query: 1553 NKTSA--CLQTLLDTKFVH-----FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNM 1605
+ T++ + TLL + + SL +++P V + R+ A + + +
Sbjct: 485 DLTASTNSIMTLLSSLLTYPQVQQCSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTL 544
Query: 1606 YSLTDQKD---LTPYLPNII 1622
S DQ L P LP+++
Sbjct: 545 LSTQDQNSSSWLIPILPDML 564
Score = 34.7 bits (76), Expect = 4.5
Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 17/171 (9%)
Query: 1405 FELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPA 1464
FE + P +V LPHL +CL S VR A ++ + + + L
Sbjct: 1089 FETAAASMDSELHPLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEK 1148
Query: 1465 LLNAVN--DDNWRTKAGSIELLGAMAYCAPKQLS-SCLPSIVPRLIEVLSDSHLRVQLSA 1521
+L + DD+ + + G+IE L C +QL +P IV ++ VL +
Sbjct: 1149 VLPWLGAIDDSVK-QEGAIEALA----CVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVR 1203
Query: 1522 AAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFID 1572
A + ++IR ++A +P DP N ++ +Q L K HF++
Sbjct: 1204 FMATQCFATLIRLMPLEAGIP-------DPPNMSAELIQ--LKAKERHFLE 1245
>AF038362-1|AAC04573.1| 1849|Homo sapiens TBP-associated factor 172
protein.
Length = 1849
Score = 48.0 bits (109), Expect = 5e-04
Identities = 49/200 (24%), Positives = 92/200 (46%), Gaps = 17/200 (8%)
Query: 1438 VRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQ--L 1495
VR T +++ ++ GV + LL + + W + G LLG A +Q +
Sbjct: 367 VRETCAQTLGVVLKHMNETGVHKTVDVLLKLLTQEQWEVRHGG--LLGIKYALAVRQDVI 424
Query: 1496 SSCLPSIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVI--RNPEIQAIVPVLLQALQDPS 1552
++ LP ++ R+IE L D V+ AAA+L V+ S++ + ++ I+ L AL +
Sbjct: 425 NTLLPKVLTRIIEGLQDLDDDVRAVAAASLVPVVESLVYLQTQKVPFIINTLWDALLELD 484
Query: 1553 NKTSA--CLQTLLDTKFVH-----FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNM 1605
+ T++ + TLL + + SL +++P V + R+ A + + +
Sbjct: 485 DLTASTNSIMTLLSSLLTYPQVQQCSIQQSLTVLVPRVWPFLHHTISSVRRAALETLFTL 544
Query: 1606 YSLTDQKD---LTPYLPNII 1622
S DQ L P LP+++
Sbjct: 545 LSTQDQNSSSWLIPILPDML 564
Score = 34.7 bits (76), Expect = 4.5
Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 17/171 (9%)
Query: 1405 FELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPA 1464
FE + P +V LPHL +CL S VR A ++ + + + L
Sbjct: 1089 FETAAASMDSELHPLLVQHLPHLYMCLQYPSTAVRHMAARCVGVMSKIATMETMNIFLEK 1148
Query: 1465 LLNAVN--DDNWRTKAGSIELLGAMAYCAPKQLS-SCLPSIVPRLIEVLSDSHLRVQLSA 1521
+L + DD+ + + G+IE L C +QL +P IV ++ VL +
Sbjct: 1149 VLPWLGAIDDSVK-QEGAIEALA----CVMEQLDVGIVPYIVLLVVPVLGRMSDQTDSVR 1203
Query: 1522 AAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFID 1572
A + ++IR ++A +P DP N ++ +Q L K HF++
Sbjct: 1204 FMATQCFATLIRLMPLEAGIP-------DPPNMSAELIQ--LKAKERHFLE 1245
>M31786-1|AAA35531.1| 589|Homo sapiens protein ( Human medium tumor
antigen-associated 61-kD protein mRNA, 5' end. ).
Length = 589
Score = 43.2 bits (97), Expect = 0.013
Identities = 56/277 (20%), Positives = 105/277 (37%), Gaps = 11/277 (3%)
Query: 1418 PYIVH-VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRT 1476
P VH +LP L VR A ++ R I S ++ AL+ + +W T
Sbjct: 83 PEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVALVKRLAGGDWFT 142
Query: 1477 KAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRNPE 1536
S G + C P+ S+ + + SD V+ +AA+ L V+
Sbjct: 143 SRTSA--CGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDN 200
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSL-ALIMPVVQRAFLDRSTETR 1595
+++ + + L + L + L AL+MP +++A D+S R
Sbjct: 201 VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVR 260
Query: 1596 KMAAQIIGNMYSLTDQKDLTPYL--PNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGE 1653
M A + QK + P + +++P ++ + D EVR+ ++ + + +
Sbjct: 261 YMVADKFTEL-----QKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSA 315
Query: 1654 SSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGL 1690
E ++ + E S L+ V+ GL
Sbjct: 316 DCRENVIMSQILPCIKELVSDANQHVKSALASVIMGL 352
Score = 34.7 bits (76), Expect = 4.5
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRY 1810
I P+ LA DE + VR A+ A I L + + AL++P L + D +WR+RY
Sbjct: 205 IIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 261
>BC132723-1|AAI32724.1| 1479|Homo sapiens CLASP1 protein protein.
Length = 1479
Score = 43.2 bits (97), Expect = 0.013
Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 2/173 (1%)
Query: 1459 KLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ 1518
K +L LL + D + +A ++ +L + P + + + + +E DSH V
Sbjct: 1286 KTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVV 1345
Query: 1519 LSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLAL 1578
+A A + S I + ++ ++Q P N + +QT + + L
Sbjct: 1346 RAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVD 1405
Query: 1579 IMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLD 1631
I+P + + + + + RK + + +YS+ + DL P+L + G K LL+
Sbjct: 1406 IIPGLLQGYDNTESSVRKASVFCLVAIYSVIGE-DLKPHLAQ-LTGSKMKLLN 1456
>BC112940-1|AAI12941.1| 1471|Homo sapiens CLASP1 protein protein.
Length = 1471
Score = 43.2 bits (97), Expect = 0.013
Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 2/173 (1%)
Query: 1459 KLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ 1518
K +L LL + D + +A ++ +L + P + + + + +E DSH V
Sbjct: 1278 KTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVV 1337
Query: 1519 LSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLAL 1578
+A A + S I + ++ ++Q P N + +QT + + L
Sbjct: 1338 RAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVD 1397
Query: 1579 IMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLD 1631
I+P + + + + + RK + + +YS+ + DL P+L + G K LL+
Sbjct: 1398 IIPGLLQGYDNTESSVRKASVFCLVAIYSVIGE-DLKPHLAQ-LTGSKMKLLN 1448
>AF347693-1|AAQ15051.1| 1538|Homo sapiens multiple asters 1 protein.
Length = 1538
Score = 43.2 bits (97), Expect = 0.013
Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 2/173 (1%)
Query: 1459 KLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ 1518
K +L LL + D + +A ++ +L + P + + + + +E DSH V
Sbjct: 1345 KTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVV 1404
Query: 1519 LSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLAL 1578
+A A + S I + ++ ++Q P N + +QT + + L
Sbjct: 1405 RAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVD 1464
Query: 1579 IMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLD 1631
I+P + + + + + RK + + +YS+ + DL P+L + G K LL+
Sbjct: 1465 IIPGLLQGYDNTESSVRKASVFCLVAIYSVIGE-DLKPHLAQ-LTGSKMKLLN 1515
>AB014522-1|BAA31597.1| 1289|Homo sapiens KIAA0622 protein protein.
Length = 1289
Score = 43.2 bits (97), Expect = 0.013
Identities = 37/173 (21%), Positives = 75/173 (43%), Gaps = 2/173 (1%)
Query: 1459 KLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ 1518
K +L LL + D + +A ++ +L + P + + + + +E DSH V
Sbjct: 1096 KTILLLLLETLGDKDHSIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVV 1155
Query: 1519 LSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLAL 1578
+A A + S I + ++ ++Q P N + +QT + + L
Sbjct: 1156 RAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVVERIAKESLLQLLVD 1215
Query: 1579 IMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLD 1631
I+P + + + + + RK + + +YS+ + DL P+L + G K LL+
Sbjct: 1216 IIPGLLQGYDNTESSVRKASVFCLVAIYSVIGE-DLKPHLAQ-LTGSKMKLLN 1266
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.030
Identities = 50/215 (23%), Positives = 94/215 (43%), Gaps = 18/215 (8%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
++ +LPAL ++ + ++ L + +Q+ + S IVP L+ +LS ++
Sbjct: 240 IQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVK 299
Query: 1517 VQLSAAAALKVIGSVIRNPEIQAIV----------PVLLQALQDPSNKTSACLQTLLDTK 1566
VQ AAL+ +G+++ + Q V P LL ++ NK + + +
Sbjct: 300 VQ---TAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAG 356
Query: 1567 FVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIPG 1624
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 357 NQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNL-TISGRKDQVAYLIQQNVIPP 415
Query: 1625 LKSSLLDPVPEVRSVSARALGAMVKGMGESSFEEL 1659
+ L +V V L ++K M E E +
Sbjct: 416 FCNLLTVKDAQVVQVVLDGLSNILK-MAEDEAETI 449
>U72395-1|AAB68948.1| 890|Homo sapiens MIP protein.
Length = 890
Score = 41.9 bits (94), Expect = 0.030
Identities = 55/225 (24%), Positives = 91/225 (40%), Gaps = 16/225 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ T A ++S+ +K ++ LL + D N
Sbjct: 434 PYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSN 493
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLS---DSHLRVQLSAAAAL-KVIG 1529
R + + + A +L L I+ L+ S +L + A L +G
Sbjct: 494 KRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVG 553
Query: 1530 SVIRNPE-IQAIVPVLLQ---ALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQR 1585
+ PE IQ ++P L+Q L+D L+ L + + + L PV QR
Sbjct: 554 HHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECL--SSVATALQSGFLPYCEPVYQR 611
Query: 1586 AF-LDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSL 1629
L + T + M + Y D KD +++ GL L
Sbjct: 612 CVNLVQKTLAQAMLNNAQPDQYEAPD-KDFMIVALDLLSGLAEGL 655
Score = 37.1 bits (82), Expect = 0.85
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 11/174 (6%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ-L 1519
+LP L + W K I +LGA+A + + LP ++P LI+ LSD V+ +
Sbjct: 398 ILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSI 457
Query: 1520 SAAAALKVIGSVIRNPEIQAIVPVLLQALQD--PSNK---TSAC--LQTLLDTKFVHFID 1572
+ + V+ P + P++ + L+ SNK +AC TL + +
Sbjct: 458 TCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELV- 516
Query: 1573 APSLALIMPVVQRAFLDRSTETRKMAAQIIGNMY-SLTDQKDLTPYLPNIIPGL 1625
P LA I+ + AF + + IG + S+ + Y+ ++P L
Sbjct: 517 -PYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPL 569
>U72069-1|AAB58254.1| 890|Homo sapiens karyopherin beta2 protein.
Length = 890
Score = 41.9 bits (94), Expect = 0.030
Identities = 55/225 (24%), Positives = 91/225 (40%), Gaps = 16/225 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ T A ++S+ +K ++ LL + D N
Sbjct: 434 PYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSN 493
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLS---DSHLRVQLSAAAAL-KVIG 1529
R + + + A +L L I+ L+ S +L + A L +G
Sbjct: 494 KRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVG 553
Query: 1530 SVIRNPE-IQAIVPVLLQ---ALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQR 1585
+ PE IQ ++P L+Q L+D L+ L + + + L PV QR
Sbjct: 554 HHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECL--SSVATALQSGFLPYCEPVYQR 611
Query: 1586 AF-LDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSL 1629
L + T + M + Y D KD +++ GL L
Sbjct: 612 CVNLVQKTLAQAMLNNAQPDQYEAPD-KDFMIVALDLLSGLAEGL 655
Score = 37.1 bits (82), Expect = 0.85
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 11/174 (6%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ-L 1519
+LP L + W K I +LGA+A + + LP ++P LI+ LSD V+ +
Sbjct: 398 ILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSI 457
Query: 1520 SAAAALKVIGSVIRNPEIQAIVPVLLQALQD--PSNK---TSAC--LQTLLDTKFVHFID 1572
+ + V+ P + P++ + L+ SNK +AC TL + +
Sbjct: 458 TCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELV- 516
Query: 1573 APSLALIMPVVQRAFLDRSTETRKMAAQIIGNMY-SLTDQKDLTPYLPNIIPGL 1625
P LA I+ + AF + + IG + S+ + Y+ ++P L
Sbjct: 517 -PYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPL 569
>U70322-1|AAC50723.1| 890|Homo sapiens transportin protein.
Length = 890
Score = 41.9 bits (94), Expect = 0.030
Identities = 55/225 (24%), Positives = 91/225 (40%), Gaps = 16/225 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ T A ++S+ +K ++ LL + D N
Sbjct: 434 PYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSN 493
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLS---DSHLRVQLSAAAAL-KVIG 1529
R + + + A +L L I+ L+ S +L + A L +G
Sbjct: 494 KRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVG 553
Query: 1530 SVIRNPE-IQAIVPVLLQ---ALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQR 1585
+ PE IQ ++P L+Q L+D L+ L + + + L PV QR
Sbjct: 554 HHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECL--SSVATALQSGFLPYCEPVYQR 611
Query: 1586 AF-LDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSL 1629
L + T + M + Y D KD +++ GL L
Sbjct: 612 CVNLVQKTLAQAMLNNAQPDQYEAPD-KDFMIVALDLLSGLAEGL 655
Score = 37.1 bits (82), Expect = 0.85
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 11/174 (6%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ-L 1519
+LP L + W K I +LGA+A + + LP ++P LI+ LSD V+ +
Sbjct: 398 ILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSI 457
Query: 1520 SAAAALKVIGSVIRNPEIQAIVPVLLQALQD--PSNK---TSAC--LQTLLDTKFVHFID 1572
+ + V+ P + P++ + L+ SNK +AC TL + +
Sbjct: 458 TCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELV- 516
Query: 1573 APSLALIMPVVQRAFLDRSTETRKMAAQIIGNMY-SLTDQKDLTPYLPNIIPGL 1625
P LA I+ + AF + + IG + S+ + Y+ ++P L
Sbjct: 517 -PYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPL 569
>BC040340-1|AAH40340.1| 890|Homo sapiens transportin 1 protein.
Length = 890
Score = 41.9 bits (94), Expect = 0.030
Identities = 55/225 (24%), Positives = 91/225 (40%), Gaps = 16/225 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ T A ++S+ +K ++ LL + D N
Sbjct: 434 PYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSN 493
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLS---DSHLRVQLSAAAAL-KVIG 1529
R + + + A +L L I+ L+ S +L + A L +G
Sbjct: 494 KRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVG 553
Query: 1530 SVIRNPE-IQAIVPVLLQ---ALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQR 1585
+ PE IQ ++P L+Q L+D L+ L + + + L PV QR
Sbjct: 554 HHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECL--SSVATALQSGFLPYCEPVYQR 611
Query: 1586 AF-LDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSL 1629
L + T + M + Y D KD +++ GL L
Sbjct: 612 CVNLVQKTLAQAMLNNAQPDQYEAPD-KDFMIVALDLLSGLAEGL 655
Score = 37.1 bits (82), Expect = 0.85
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 11/174 (6%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ-L 1519
+LP L + W K I +LGA+A + + LP ++P LI+ LSD V+ +
Sbjct: 398 ILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSI 457
Query: 1520 SAAAALKVIGSVIRNPEIQAIVPVLLQALQD--PSNK---TSAC--LQTLLDTKFVHFID 1572
+ + V+ P + P++ + L+ SNK +AC TL + +
Sbjct: 458 TCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELV- 516
Query: 1573 APSLALIMPVVQRAFLDRSTETRKMAAQIIGNMY-SLTDQKDLTPYLPNIIPGL 1625
P LA I+ + AF + + IG + S+ + Y+ ++P L
Sbjct: 517 -PYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPL 569
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.030
Identities = 50/215 (23%), Positives = 94/215 (43%), Gaps = 18/215 (8%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
++ +LPAL ++ + ++ L + +Q+ + S IVP L+ +LS ++
Sbjct: 240 IQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVK 299
Query: 1517 VQLSAAAALKVIGSVIRNPEIQAIV----------PVLLQALQDPSNKTSACLQTLLDTK 1566
VQ AAL+ +G+++ + Q V P LL ++ NK + + +
Sbjct: 300 VQ---TAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAG 356
Query: 1567 FVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIPG 1624
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 357 NQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNL-TISGRKDQVAYLIQQNVIPP 415
Query: 1625 LKSSLLDPVPEVRSVSARALGAMVKGMGESSFEEL 1659
+ L +V V L ++K M E E +
Sbjct: 416 FCNLLTVKDAQVVQVVLDGLSNILK-MAEDEAETI 449
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.030
Identities = 50/215 (23%), Positives = 94/215 (43%), Gaps = 18/215 (8%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
++ +LPAL ++ + ++ L + +Q+ + S IVP L+ +LS ++
Sbjct: 240 IQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVK 299
Query: 1517 VQLSAAAALKVIGSVIRNPEIQAIV----------PVLLQALQDPSNKTSACLQTLLDTK 1566
VQ AAL+ +G+++ + Q V P LL ++ NK + + +
Sbjct: 300 VQ---TAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAG 356
Query: 1567 FVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIPG 1624
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 357 NQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNL-TISGRKDQVAYLIQQNVIPP 415
Query: 1625 LKSSLLDPVPEVRSVSARALGAMVKGMGESSFEEL 1659
+ L +V V L ++K M E E +
Sbjct: 416 FCNLLTVKDAQVVQVVLDGLSNILK-MAEDEAETI 449
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 41.9 bits (94), Expect = 0.030
Identities = 50/215 (23%), Positives = 94/215 (43%), Gaps = 18/215 (8%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
++ +LPAL ++ + ++ L + +Q+ + S IVP L+ +LS ++
Sbjct: 240 IQEILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVK 299
Query: 1517 VQLSAAAALKVIGSVIRNPEIQAIV----------PVLLQALQDPSNKTSACLQTLLDTK 1566
VQ AAL+ +G+++ + Q V P LL ++ NK + + +
Sbjct: 300 VQ---TAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAG 356
Query: 1567 FVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIPG 1624
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 357 NQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNL-TISGRKDQVAYLIQQNVIPP 415
Query: 1625 LKSSLLDPVPEVRSVSARALGAMVKGMGESSFEEL 1659
+ L +V V L ++K M E E +
Sbjct: 416 FCNLLTVKDAQVVQVVLDGLSNILK-MAEDEAETI 449
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 41.5 bits (93), Expect = 0.039
Identities = 50/212 (23%), Positives = 92/212 (43%), Gaps = 18/212 (8%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLRVQL 1519
+LPAL ++ + ++ L + +Q+ + S IVP L+ +LS ++VQ
Sbjct: 3 ILPALCVLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQ- 61
Query: 1520 SAAAALKVIGSVIRNPEIQAIV----------PVLLQALQDPSNKTSACLQTLLDTKFVH 1569
AAL+ +G+++ + Q V P LL ++ NK + + +
Sbjct: 62 --TAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQ 119
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIPGLKS 1627
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP +
Sbjct: 120 QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNL-TISGRKDQVAYLIQQNVIPPFCN 178
Query: 1628 SLLDPVPEVRSVSARALGAMVKGMGESSFEEL 1659
L +V V L ++K M E E +
Sbjct: 179 LLTVKDAQVVQVVLDGLSNILK-MAEDEAETI 209
>BC050341-1|AAH50341.1| 1230|Homo sapiens cullin-associated and
neddylation-dissociated 1 protein.
Length = 1230
Score = 41.5 bits (93), Expect = 0.039
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 8/135 (5%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSD--SHLRVQ 1518
++ AL + + + +T+ +L + P L+ +P +VP +I L+D S ++
Sbjct: 435 IVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLK 494
Query: 1519 LSAAAALKVI----GSVIRNPEIQAIVPVLLQALQDPSNK--TSACLQTLLDTKFVHFID 1572
+ A + L VI + +P +QA+VP ++ + DP K + A L T K + +D
Sbjct: 495 IDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLD 554
Query: 1573 APSLALIMPVVQRAF 1587
PS P ++ F
Sbjct: 555 QPSSFDATPYIKDLF 569
Score = 35.9 bits (79), Expect = 2.0
Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 21/276 (7%)
Query: 1502 IVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQT 1561
+V ++++L D + VQ A L + S ++ +++ IV L + +
Sbjct: 49 VVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSI 108
Query: 1562 LLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKD-------- 1613
L T A S + + V + R T + + +L D
Sbjct: 109 GLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGL 168
Query: 1614 LTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSFEELLPWLMHTLTSETSS 1673
L + P+I+ L L P VR + ALG +V G F +L+ L+ SE S
Sbjct: 169 LVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLL----SELSK 224
Query: 1674 VDRSGAAQGLSEVVAGLGVQKLHKIMPGDTPACNRNKVIPTYIIATAERTDIAPHVKDGY 1733
D + + +A + Q H+I G+ K+IP ++ D +++
Sbjct: 225 NDSMSTTRTYIQCIAAISRQAGHRI--GE----YLEKIIP-LVVKFCNVDD--DELREYC 275
Query: 1734 IMMFIYMPGAFTDEFTPYIGQIINPILKALADENEY 1769
I F E P++ IIN LK L + Y
Sbjct: 276 IQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNY 311
>BC026220-1|AAH26220.1| 1159|Homo sapiens CAND1 protein protein.
Length = 1159
Score = 41.5 bits (93), Expect = 0.039
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 8/135 (5%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSD--SHLRVQ 1518
++ AL + + + +T+ +L + P L+ +P +VP +I L+D S ++
Sbjct: 364 IVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLK 423
Query: 1519 LSAAAALKVI----GSVIRNPEIQAIVPVLLQALQDPSNK--TSACLQTLLDTKFVHFID 1572
+ A + L VI + +P +QA+VP ++ + DP K + A L T K + +D
Sbjct: 424 IDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLD 483
Query: 1573 APSLALIMPVVQRAF 1587
PS P ++ F
Sbjct: 484 QPSSFDATPYIKDLF 498
>AK027404-1|BAB55090.1| 908|Homo sapiens protein ( Homo sapiens cDNA
FLJ14498 fis, clone NT2RM1000055, highly similar to
Rattus norvegicus mRNA for TIP120. ).
Length = 908
Score = 41.5 bits (93), Expect = 0.039
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 8/135 (5%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSD--SHLRVQ 1518
++ AL + + + +T+ +L + P L+ +P +VP +I L+D S ++
Sbjct: 113 IVKALHKQMKEKSVKTRQCCFNILTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLK 172
Query: 1519 LSAAAALKVI----GSVIRNPEIQAIVPVLLQALQDPSNK--TSACLQTLLDTKFVHFID 1572
+ A + L VI + +P +QA+VP ++ + DP K + A L T K + +D
Sbjct: 173 IDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLD 232
Query: 1573 APSLALIMPVVQRAF 1587
PS P ++ F
Sbjct: 233 QPSSFDATPYIKDLF 247
>AF157326-1|AAF67492.1| 1230|Homo sapiens TIP120 protein protein.
Length = 1230
Score = 41.5 bits (93), Expect = 0.039
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 8/135 (5%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSD--SHLRVQ 1518
++ AL + + + +T+ +L + P L+ +P +VP +I L+D S ++
Sbjct: 435 IVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLK 494
Query: 1519 LSAAAALKVI----GSVIRNPEIQAIVPVLLQALQDPSNK--TSACLQTLLDTKFVHFID 1572
+ A + L VI + +P +QA+VP ++ + DP K + A L T K + +D
Sbjct: 495 IDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLD 554
Query: 1573 APSLALIMPVVQRAF 1587
PS P ++ F
Sbjct: 555 QPSSFDATPYIKDLF 569
Score = 35.9 bits (79), Expect = 2.0
Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 21/276 (7%)
Query: 1502 IVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQT 1561
+V ++++L D + VQ A L + S ++ +++ IV L + +
Sbjct: 49 VVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSI 108
Query: 1562 LLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKD-------- 1613
L T A S + + V + R T + + +L D
Sbjct: 109 GLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGL 168
Query: 1614 LTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSFEELLPWLMHTLTSETSS 1673
L + P+I+ L L P VR + ALG +V G F +L+ L+ SE S
Sbjct: 169 LVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLL----SELSK 224
Query: 1674 VDRSGAAQGLSEVVAGLGVQKLHKIMPGDTPACNRNKVIPTYIIATAERTDIAPHVKDGY 1733
D + + +A + Q H+I G+ K+IP ++ D +++
Sbjct: 225 NDSMSTTRTYIQCIAAISRQAGHRI--GE----YLEKIIP-LVVKFCNVDD--DELREYC 275
Query: 1734 IMMFIYMPGAFTDEFTPYIGQIINPILKALADENEY 1769
I F E P++ IIN LK L + Y
Sbjct: 276 IQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNY 311
>AB020636-1|BAA74852.2| 1277|Homo sapiens KIAA0829 protein protein.
Length = 1277
Score = 41.5 bits (93), Expect = 0.039
Identities = 34/135 (25%), Positives = 64/135 (47%), Gaps = 8/135 (5%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSD--SHLRVQ 1518
++ AL + + + +T+ +L + P L+ +P +VP +I L+D S ++
Sbjct: 482 IVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLK 541
Query: 1519 LSAAAALKVI----GSVIRNPEIQAIVPVLLQALQDPSNK--TSACLQTLLDTKFVHFID 1572
+ A + L VI + +P +QA+VP ++ + DP K + A L T K + +D
Sbjct: 542 IDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLD 601
Query: 1573 APSLALIMPVVQRAF 1587
PS P ++ F
Sbjct: 602 QPSSFDATPYIKDLF 616
Score = 35.9 bits (79), Expect = 2.0
Identities = 60/276 (21%), Positives = 103/276 (37%), Gaps = 21/276 (7%)
Query: 1502 IVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQT 1561
+V ++++L D + VQ A L + S ++ +++ IV L + +
Sbjct: 96 VVKMILKLLEDKNGEVQNLAVKCLGPLVSKVKEYQVETIVDTLCTNMLSDKEQLRDISSI 155
Query: 1562 LLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKD-------- 1613
L T A S + + V + R T + + +L D
Sbjct: 156 GLKTVIGELPPASSGSALAANVCKKITGRLTSAIAKQEDVSVQLEALDIMADMLSRQGGL 215
Query: 1614 LTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSFEELLPWLMHTLTSETSS 1673
L + P+I+ L L P VR + ALG +V G F +L+ L+ SE S
Sbjct: 216 LVNFHPSILTCLLPQLTSPRLAVRKRTIIALGHLVMSCGNIVFVDLIEHLL----SELSK 271
Query: 1674 VDRSGAAQGLSEVVAGLGVQKLHKIMPGDTPACNRNKVIPTYIIATAERTDIAPHVKDGY 1733
D + + +A + Q H+I G+ K+IP ++ D +++
Sbjct: 272 NDSMSTTRTYIQCIAAISRQAGHRI--GE----YLEKIIP-LVVKFCNVDD--DELREYC 322
Query: 1734 IMMFIYMPGAFTDEFTPYIGQIINPILKALADENEY 1769
I F E P++ IIN LK L + Y
Sbjct: 323 IQAFESFVRRCPKEVYPHVSTIINICLKYLTYDPNY 358
>CR450340-1|CAG29336.1| 589|Homo sapiens PPP2R1A protein.
Length = 589
Score = 41.1 bits (92), Expect = 0.052
Identities = 55/277 (19%), Positives = 104/277 (37%), Gaps = 11/277 (3%)
Query: 1418 PYIVH-VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRT 1476
P VH +LP L VR A ++ R I S ++ L+ + +W T
Sbjct: 83 PEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFT 142
Query: 1477 KAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRNPE 1536
S G + C P+ S+ + + SD V+ +AA+ L V+
Sbjct: 143 SRTSA--CGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDN 200
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSL-ALIMPVVQRAFLDRSTETR 1595
+++ + + L + L + L AL+MP +++A D+S R
Sbjct: 201 VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVR 260
Query: 1596 KMAAQIIGNMYSLTDQKDLTPYL--PNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGE 1653
M A + QK + P + +++P ++ + D EVR+ ++ + + +
Sbjct: 261 YMVADKFTEL-----QKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSA 315
Query: 1654 SSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGL 1690
E ++ + E S L+ V+ GL
Sbjct: 316 DCRENVIMSQILPCIKELVSDANQHVKSALASVIMGL 352
Score = 34.7 bits (76), Expect = 4.5
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRY 1810
I P+ LA DE + VR A+ A I L + + AL++P L + D +WR+RY
Sbjct: 205 IIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 261
>BC001537-1|AAH01537.1| 589|Homo sapiens protein phosphatase 2
(formerly 2A), regulatory subunit A , alpha isoform
protein.
Length = 589
Score = 41.1 bits (92), Expect = 0.052
Identities = 55/277 (19%), Positives = 104/277 (37%), Gaps = 11/277 (3%)
Query: 1418 PYIVH-VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRT 1476
P VH +LP L VR A ++ R I S ++ L+ + +W T
Sbjct: 83 PEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFT 142
Query: 1477 KAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRNPE 1536
S G + C P+ S+ + + SD V+ +AA+ L V+
Sbjct: 143 SRTSA--CGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDN 200
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSL-ALIMPVVQRAFLDRSTETR 1595
+++ + + L + L + L AL+MP +++A D+S R
Sbjct: 201 VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVR 260
Query: 1596 KMAAQIIGNMYSLTDQKDLTPYL--PNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGE 1653
M A + QK + P + +++P ++ + D EVR+ ++ + + +
Sbjct: 261 YMVADKFTEL-----QKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSA 315
Query: 1654 SSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGL 1690
E ++ + E S L+ V+ GL
Sbjct: 316 DCRENVIMSQILPCIKELVSDANQHVKSALASVIMGL 352
Score = 34.7 bits (76), Expect = 4.5
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRY 1810
I P+ LA DE + VR A+ A I L + + AL++P L + D +WR+RY
Sbjct: 205 IIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 261
>J02902-1|AAA36399.1| 589|Homo sapiens phosphatase 2A regulatory
subunit protein.
Length = 589
Score = 40.7 bits (91), Expect = 0.069
Identities = 55/277 (19%), Positives = 104/277 (37%), Gaps = 11/277 (3%)
Query: 1418 PYIVH-VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRT 1476
P VH +LP L VR A ++ R I S ++ L+ + +W T
Sbjct: 83 PEYVHCLLPPLESLATVEETVVRDKAVESLRAISHEHSPSDLEAHFVPLVKRLAGGDWFT 142
Query: 1477 KAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRNPE 1536
S G + C P+ S+ + + SD V+ +AA+ L V+
Sbjct: 143 SRTSA--CGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLELDN 200
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSL-ALIMPVVQRAFLDRSTETR 1595
+++ + + L + L + L AL+MP +++A D+S R
Sbjct: 201 VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWAVR 260
Query: 1596 KMAAQIIGNMYSLTDQKDLTPYL--PNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGE 1653
M A + QK + P + +++P ++ + D EVR+ ++ + + +
Sbjct: 261 YMVADKFTEL-----QKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSA 315
Query: 1654 SSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGL 1690
E ++ + E S L+ V+ GL
Sbjct: 316 DCRENVIMSQILPCIKELVSDANQHVKSALASVIMGL 352
>BC072420-1|AAH72420.1| 887|Homo sapiens transportin 2 (importin 3,
karyopherin beta 2b) protein.
Length = 887
Score = 40.3 bits (90), Expect = 0.091
Identities = 55/225 (24%), Positives = 90/225 (40%), Gaps = 16/225 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ A T A ++S+ +K ++ LL + D N
Sbjct: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGN 490
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVL---SDSHLRVQLSAAAAL-KVIG 1529
R + + + A +L L I+ L+ +L + A L +G
Sbjct: 491 KRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVG 550
Query: 1530 SVIRNPE-IQAIVPVLLQ---ALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQR 1585
+ PE IQ ++P L+Q L+D L+ L + + + L PV QR
Sbjct: 551 HHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECL--SSVATALQSGFLPYCEPVYQR 608
Query: 1586 AF-LDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSL 1629
L + T + M Y D KD +++ GL L
Sbjct: 609 CVTLVQKTLAQAMMYTQHPEQYEAPD-KDFMIVALDLLSGLAEGL 652
Score = 38.3 bits (85), Expect = 0.37
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 5/110 (4%)
Query: 1441 AADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLP 1500
A D A + L H +LP L + W K I +LGA+A + + LP
Sbjct: 379 ALDVLANVFREELLPH----LLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLP 434
Query: 1501 SIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVIRNPEIQAIVPVLLQALQ 1549
++P LI+ LSD V+ A L + V+ P + P++ + L+
Sbjct: 435 ELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLK 484
>BC027596-1|AAH27596.1| 667|Homo sapiens protein phosphatase 2
(formerly 2A), regulatory subunit A, beta isoform
protein.
Length = 667
Score = 40.3 bits (90), Expect = 0.091
Identities = 51/277 (18%), Positives = 104/277 (37%), Gaps = 11/277 (3%)
Query: 1423 VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVK-LVLPALLNAVNDDNWRTKAGSI 1481
++P D VR A + I LS ++ LV+P L A D +WR +
Sbjct: 217 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 276
Query: 1482 ELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGS--VIRNPE--- 1536
+ + +++ L ++P +L D V+ +AA +K +G I + E
Sbjct: 277 DRFSELQKAMGPKIT--LNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETII 334
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRK 1596
+ I+P + + + D + + L +++ ++ ++P+ D + R
Sbjct: 335 MNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVR- 393
Query: 1597 MAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSF 1656
II N+ + + + +++P + D VR + + +G F
Sbjct: 394 --LNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 451
Query: 1657 EELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQ 1693
+E L L + R A L ++V G +
Sbjct: 452 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTE 488
Score = 35.1 bits (77), Expect = 3.4
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRYSSV 1813
I P+ +LA DE + VR A+ A I L ++ + L++P L + D +WR+RY
Sbjct: 217 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 276
Query: 1814 QLLGDL 1819
+L
Sbjct: 277 DRFSEL 282
>BC018314-1|AAH18314.1| 771|Homo sapiens Unknown (protein for
IMAGE:4154236) protein.
Length = 771
Score = 40.3 bits (90), Expect = 0.091
Identities = 55/225 (24%), Positives = 90/225 (40%), Gaps = 16/225 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ A T A ++S+ +K ++ LL + D N
Sbjct: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGN 490
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVL---SDSHLRVQLSAAAAL-KVIG 1529
R + + + A +L L I+ L+ +L + A L +G
Sbjct: 491 KRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVG 550
Query: 1530 SVIRNPE-IQAIVPVLLQ---ALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQR 1585
+ PE IQ ++P L+Q L+D L+ L + + + L PV QR
Sbjct: 551 HHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECL--SSVATALQSGFLPYCEPVYQR 608
Query: 1586 AF-LDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSL 1629
L + T + M Y D KD +++ GL L
Sbjct: 609 CVTLVQKTLAQAMMYTQHPEQYEAPD-KDFMIVALDLLSGLAEGL 652
Score = 38.3 bits (85), Expect = 0.37
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 5/110 (4%)
Query: 1441 AADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLP 1500
A D A + L H +LP L + W K I +LGA+A + + LP
Sbjct: 379 ALDVLANVFREELLPH----LLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLP 434
Query: 1501 SIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVIRNPEIQAIVPVLLQALQ 1549
++P LI+ LSD V+ A L + V+ P + P++ + L+
Sbjct: 435 ELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLK 484
>AF163473-1|AAG39644.1| 601|Homo sapiens protein phosphatase 2A
regulatory subunit A beta isoform protein.
Length = 601
Score = 40.3 bits (90), Expect = 0.091
Identities = 51/277 (18%), Positives = 104/277 (37%), Gaps = 11/277 (3%)
Query: 1423 VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVK-LVLPALLNAVNDDNWRTKAGSI 1481
++P D VR A + I LS ++ LV+P L A D +WR +
Sbjct: 217 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 276
Query: 1482 ELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGS--VIRNPE--- 1536
+ + +++ L ++P +L D V+ +AA +K +G I + E
Sbjct: 277 DRFSELQKAMGPKIT--LNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETII 334
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRK 1596
+ I+P + + + D + + L +++ ++ ++P+ D + R
Sbjct: 335 MNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVR- 393
Query: 1597 MAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSF 1656
II N+ + + + +++P + D VR + + +G F
Sbjct: 394 --LNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 451
Query: 1657 EELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQ 1693
+E L L + R A L ++V G +
Sbjct: 452 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTE 488
Score = 35.1 bits (77), Expect = 3.4
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRYSSV 1813
I P+ +LA DE + VR A+ A I L ++ + L++P L + D +WR+RY
Sbjct: 217 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 276
Query: 1814 QLLGDL 1819
+L
Sbjct: 277 DRFSEL 282
>AF087438-1|AAC69624.1| 601|Homo sapiens protein phosphatase 2
subunit A isoform beta protein.
Length = 601
Score = 40.3 bits (90), Expect = 0.091
Identities = 51/277 (18%), Positives = 104/277 (37%), Gaps = 11/277 (3%)
Query: 1423 VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVK-LVLPALLNAVNDDNWRTKAGSI 1481
++P D VR A + I LS ++ LV+P L A D +WR +
Sbjct: 217 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 276
Query: 1482 ELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGS--VIRNPE--- 1536
+ + +++ L ++P +L D V+ +AA +K +G I + E
Sbjct: 277 DRFSELQKAMGPKIT--LNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETII 334
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRK 1596
+ I+P + + + D + + L +++ ++ ++P+ D + R
Sbjct: 335 MNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVR- 393
Query: 1597 MAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSF 1656
II N+ + + + +++P + D VR + + +G F
Sbjct: 394 --LNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 451
Query: 1657 EELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQ 1693
+E L L + R A L ++V G +
Sbjct: 452 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTE 488
Score = 35.1 bits (77), Expect = 3.4
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRYSSV 1813
I P+ +LA DE + VR A+ A I L ++ + L++P L + D +WR+RY
Sbjct: 217 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 276
Query: 1814 QLLGDL 1819
+L
Sbjct: 277 DRFSEL 282
>AF083439-1|AAC63525.1| 601|Homo sapiens protein phosphatase 2A
regulatory subunit A, beta isoform protein.
Length = 601
Score = 40.3 bits (90), Expect = 0.091
Identities = 51/277 (18%), Positives = 104/277 (37%), Gaps = 11/277 (3%)
Query: 1423 VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVK-LVLPALLNAVNDDNWRTKAGSI 1481
++P D VR A + I LS ++ LV+P L A D +WR +
Sbjct: 217 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 276
Query: 1482 ELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGS--VIRNPE--- 1536
+ + +++ L ++P +L D V+ +AA +K +G I + E
Sbjct: 277 DRFSELQKAMGPKIT--LNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETII 334
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRK 1596
+ I+P + + + D + + L +++ ++ ++P+ D + R
Sbjct: 335 MNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVR- 393
Query: 1597 MAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSF 1656
II N+ + + + +++P + D VR + + +G F
Sbjct: 394 --LNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 451
Query: 1657 EELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQ 1693
+E L L + R A L ++V G +
Sbjct: 452 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTE 488
Score = 35.1 bits (77), Expect = 3.4
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRYSSV 1813
I P+ +LA DE + VR A+ A I L ++ + L++P L + D +WR+RY
Sbjct: 217 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 276
Query: 1814 QLLGDL 1819
+L
Sbjct: 277 DRFSEL 282
>AF019039-1|AAB83973.1| 896|Homo sapiens transportin2 protein.
Length = 896
Score = 40.3 bits (90), Expect = 0.091
Identities = 55/225 (24%), Positives = 90/225 (40%), Gaps = 16/225 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ A T A ++S+ +K ++ LL + D N
Sbjct: 430 PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGN 489
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVL---SDSHLRVQLSAAAAL-KVIG 1529
R + + + A +L L I+ L+ +L + A L +G
Sbjct: 490 KRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVG 549
Query: 1530 SVIRNPE-IQAIVPVLLQ---ALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQR 1585
+ PE IQ ++P L+Q L+D L+ L + + + L PV QR
Sbjct: 550 HHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECL--SSVATALQSGFLPYCEPVYQR 607
Query: 1586 AF-LDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSL 1629
L + T + M Y D KD +++ GL L
Sbjct: 608 CVTLVQKTLAQAMMYTQHPEQYEAPD-KDFMIVALDLLTGLAEGL 651
Score = 34.7 bits (76), Expect = 4.5
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 1/77 (1%)
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVI 1532
W K I +LGA+A + + LP ++P LI+ LSD V+ A L + V+
Sbjct: 407 WVVKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVV 466
Query: 1533 RNPEIQAIVPVLLQALQ 1549
P + P++ + L+
Sbjct: 467 SQPPDMHLKPLMTELLK 483
>AB210011-1|BAE06093.1| 1051|Homo sapiens TNPO2 variant protein
protein.
Length = 1051
Score = 40.3 bits (90), Expect = 0.091
Identities = 55/225 (24%), Positives = 90/225 (40%), Gaps = 16/225 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ A T A ++S+ +K ++ LL + D N
Sbjct: 595 PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGN 654
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVL---SDSHLRVQLSAAAAL-KVIG 1529
R + + + A +L L I+ L+ +L + A L +G
Sbjct: 655 KRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVG 714
Query: 1530 SVIRNPE-IQAIVPVLLQ---ALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQR 1585
+ PE IQ ++P L+Q L+D L+ L + + + L PV QR
Sbjct: 715 HHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECL--SSVATALQSGFLPYCEPVYQR 772
Query: 1586 AF-LDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSL 1629
L + T + M Y D KD +++ GL L
Sbjct: 773 CVTLVQKTLAQAMMYTQHPEQYEAPD-KDFMIVALDLLSGLAEGL 816
Score = 38.3 bits (85), Expect = 0.37
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 5/110 (4%)
Query: 1441 AADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLP 1500
A D A + L H +LP L + W K I +LGA+A + + LP
Sbjct: 543 ALDVLANVFREELLPH----LLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLP 598
Query: 1501 SIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVIRNPEIQAIVPVLLQALQ 1549
++P LI+ LSD V+ A L + V+ P + P++ + L+
Sbjct: 599 ELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLK 648
>M65254-1|AAA59983.1| 575|Homo sapiens protein phosphatase-2A
regulatory subunit-beta protein.
Length = 575
Score = 39.9 bits (89), Expect = 0.12
Identities = 51/277 (18%), Positives = 104/277 (37%), Gaps = 11/277 (3%)
Query: 1423 VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVK-LVLPALLNAVNDDNWRTKAGSI 1481
++P D VR A + I LS ++ LV+P L A D +WR +
Sbjct: 191 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 250
Query: 1482 ELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGS--VIRNPE--- 1536
+ + +++ L ++P +L D V+ +AA +K +G I + E
Sbjct: 251 DRFSELQKAMGPKIT--LNDLIPAFQNLLKDCEAEVRAAAAHKVKELGENLPIEDRETII 308
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRK 1596
+ I+P + + + D + + L +++ ++ ++P+ D + R
Sbjct: 309 MNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLLPLFLAQLKDECPDVR- 367
Query: 1597 MAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSF 1656
II N+ + + + +++P + D VR + + +G F
Sbjct: 368 --LNIISNLDCVNEVIGIRRLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 425
Query: 1657 EELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQ 1693
+E L L + R A L ++V G +
Sbjct: 426 DEKLNSLCMAWLVDHVYAIREAATNNLMKLVQKFGTE 462
Score = 35.1 bits (77), Expect = 3.4
Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 2/66 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRYSSV 1813
I P+ +LA DE + VR A+ A I L ++ + L++P L + D +WR+RY
Sbjct: 191 IVPLFTSLASDEQDSVRLLAVEACVSIAQLLSQDDLETLVMPTLRQAAEDKSWRVRYMVA 250
Query: 1814 QLLGDL 1819
+L
Sbjct: 251 DRFSEL 256
>BC030006-1|AAH30006.1| 956|Homo sapiens C20orf132 protein protein.
Length = 956
Score = 39.9 bits (89), Expect = 0.12
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 14/163 (8%)
Query: 1446 ARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAG-SIELLGAMAYCAPKQLSSCLPSI-- 1502
A L ++L A V +L LLN ND + T AG +ELL + ++ LPSI
Sbjct: 716 ALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRS-------PVAKRLPSIYS 768
Query: 1503 VPRLIEVLSD-SHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNK-TSACLQ 1560
V R + L D +HL L ++G +I++++P ++ +L++ K + +Q
Sbjct: 769 VARFKDWLQDGNHLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQ 828
Query: 1561 TLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIG 1603
LL + V +D +LA +M + F D ++ + + + G
Sbjct: 829 ILL--QLVRTMDFTTLAAMMRTLFSLFGDVRSDVHRFSVTLFG 869
>AL136172-8|CAI95720.1| 669|Homo sapiens chromosome 20 open reading
frame 132 protein.
Length = 669
Score = 39.9 bits (89), Expect = 0.12
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 14/163 (8%)
Query: 1446 ARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAG-SIELLGAMAYCAPKQLSSCLPSI-- 1502
A L ++L A V +L LLN ND + T AG +ELL + ++ LPSI
Sbjct: 333 ALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRS-------PVAKRLPSIYS 385
Query: 1503 VPRLIEVLSD-SHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNK-TSACLQ 1560
V R + L D +HL L ++G +I++++P ++ +L++ K + +Q
Sbjct: 386 VARFKDWLQDGNHLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQ 445
Query: 1561 TLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIG 1603
LL + V +D +LA +M + F D ++ + + + G
Sbjct: 446 ILL--QLVRTMDFTTLAAMMRTLFSLFGDVRSDVHRFSVTLFG 486
>AL136172-5|CAI95718.2| 1068|Homo sapiens chromosome 20 open reading
frame 132 protein.
Length = 1068
Score = 39.9 bits (89), Expect = 0.12
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 14/163 (8%)
Query: 1446 ARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAG-SIELLGAMAYCAPKQLSSCLPSI-- 1502
A L ++L A V +L LLN ND + T AG +ELL + ++ LPSI
Sbjct: 732 ALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRS-------PVAKRLPSIYS 784
Query: 1503 VPRLIEVLSD-SHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNK-TSACLQ 1560
V R + L D +HL L ++G +I++++P ++ +L++ K + +Q
Sbjct: 785 VARFKDWLQDGNHLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQ 844
Query: 1561 TLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIG 1603
LL + V +D +LA +M + F D ++ + + + G
Sbjct: 845 ILL--QLVRTMDFTTLAAMMRTLFSLFGDVRSDVHRFSVTLFG 885
>AL031659-4|CAI42665.2| 1068|Homo sapiens chromosome 20 open reading
frame 132 protein.
Length = 1068
Score = 39.9 bits (89), Expect = 0.12
Identities = 44/163 (26%), Positives = 78/163 (47%), Gaps = 14/163 (8%)
Query: 1446 ARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAG-SIELLGAMAYCAPKQLSSCLPSI-- 1502
A L ++L A V +L LLN ND + T AG +ELL + ++ LPSI
Sbjct: 732 ALLERNQLLAQKVMYLLVPLLNRGNDKHKLTSAGFFVELLRS-------PVAKRLPSIYS 784
Query: 1503 VPRLIEVLSD-SHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNK-TSACLQ 1560
V R + L D +HL L ++G +I++++P ++ +L++ K + +Q
Sbjct: 785 VARFKDWLQDGNHLFRILGLRGLYNLVGHQEMREDIKSLLPYIVDSLRETDEKIVLSAIQ 844
Query: 1561 TLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIG 1603
LL + V +D +LA +M + F D ++ + + + G
Sbjct: 845 ILL--QLVRTMDFTTLAAMMRTLFSLFGDVRSDVHRFSVTLFG 885
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 variant
protein.
Length = 521
Score = 39.1 bits (87), Expect = 0.21
Identities = 42/176 (23%), Positives = 82/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA+ I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAARAISNL-TISGRKDQVEYLVQQNVIP 414
>BC047240-1|AAH47240.1| 855|Homo sapiens HEAT repeat containing 2
protein.
Length = 855
Score = 38.7 bits (86), Expect = 0.28
Identities = 58/238 (24%), Positives = 95/238 (39%), Gaps = 17/238 (7%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDTARLIMSRLSA--HGVKLVLPALLN--AVNDDN 1473
P+ +LP LL CL D ++ R A L + R + + +LPAL A +
Sbjct: 72 PWARLLLPRLLRCLSDPAEGCRALAVHLLDLGLRRAARPRDALPRLLPALAARLAGHVPA 131
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRL---IEVLSDSHL-------RVQLSAAA 1523
R EL A+ + C ++ P L + L S L R S AA
Sbjct: 132 RRPPEACEELRLALVQLLGLAVDLCGAALAPHLDDALRALRCSLLDPFAAVRRESCSCAA 191
Query: 1524 ALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVV 1583
AL + + ++++ L+Q + K +HF + S+ ++
Sbjct: 192 ALAQATPDHFHMQSESLIGPLMQTISHQHWKVRVAAIEATGA-VIHFGNGKSVDDVLSHF 250
Query: 1584 QRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSA 1641
+ D + R+ A ++G L +D + +IP L SSL D VPEVR ++A
Sbjct: 251 AQRLFDDVPQVRRAVASVVGGW--LLCLRDRYSFFHKLIPLLLSSLNDEVPEVRQLAA 306
Score = 36.3 bits (80), Expect = 1.5
Identities = 46/171 (26%), Positives = 71/171 (41%), Gaps = 15/171 (8%)
Query: 1530 SVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDT---KFVHFIDA-----PSLA--LI 1579
+ + P + ++P LL+ L DP+ A LLD + DA P+LA L
Sbjct: 67 TAFQGPWARLLLPRLLRCLSDPAEGCRALAVHLLDLGLRRAARPRDALPRLLPALAARLA 126
Query: 1580 MPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSV 1639
V R + E R Q++G L L P+L + + L+ SLLDP VR
Sbjct: 127 GHVPARRPPEACEELRLALVQLLGLAVDLCGAA-LAPHLDDALRALRCSLLDPFAAVRRE 185
Query: 1640 SARALGAMVKGMGE---SSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVV 1687
S A+ + + E L+ LM T++ + V R A + V+
Sbjct: 186 SCSCAAALAQATPDHFHMQSESLIGPLMQTISHQHWKV-RVAAIEATGAVI 235
>AF007748-1|AAB71349.1| 887|Homo sapiens karyopherin beta2b homolog
protein.
Length = 887
Score = 38.3 bits (85), Expect = 0.37
Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 5/110 (4%)
Query: 1441 AADDTARLIMSRLSAHGVKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLP 1500
A D A + L H +LP L + W K I +LGA+A + + LP
Sbjct: 379 ALDVLANVFREELLPH----LLPLLKGLLFHPEWVVKESGILVLGAIAEGCMQGMVPYLP 434
Query: 1501 SIVPRLIEVLSDSHLRVQLSAAAAL-KVIGSVIRNPEIQAIVPVLLQALQ 1549
++P LI+ LSD V+ A L + V+ P + P++ + L+
Sbjct: 435 ELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLK 484
Score = 37.5 bits (83), Expect = 0.64
Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 9/138 (6%)
Query: 1418 PYIVHVLPHLLLCLGDGSQYVRTAADDT----ARLIMSRLSAHGVKLVLPALLNAVNDDN 1473
PY+ ++PHL+ CL D VR+ A T A ++S+ +K ++ LL + D N
Sbjct: 431 PYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGN 490
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVL---SDSHLRVQLSAAAAL-KVIG 1529
+ + + + A +L L I+ L+ +L + A L +G
Sbjct: 491 KKVQEAACIAFATLEEKACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVG 550
Query: 1530 SVIRNPE-IQAIVPVLLQ 1546
+ PE IQ ++P L+Q
Sbjct: 551 HHLNQPEYIQKLMPPLIQ 568
Score = 34.3 bits (75), Expect = 6.0
Identities = 38/160 (23%), Positives = 67/160 (41%), Gaps = 9/160 (5%)
Query: 1881 ALHSYDKRQVAARTLGDLVRKLGERVLPEIVPILERGLRSPRADQRQGVCIGLGEILAST 1940
AL ++ R+ +A L L E +LP ++P+L+ L P ++ + LG I A
Sbjct: 366 ALSDWNLRKCSAAALDVLANVFREELLPHLLPLLKGLLFHPEWVVKESGILVLGAI-AEG 424
Query: 1941 SRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDS-LHATIGNKALDDILPYMLEGLK 1999
++ + L+P + L D VR A T H + + P M E LK
Sbjct: 425 CMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLK 484
Query: 2000 DPDPAVADATLDGLKQASLRIMSIKSRA---VLPYLIPVL 2036
+ D + A + +++ +A ++PYL +L
Sbjct: 485 ----RILDGNKKVQEAACIAFATLEEKACTELVPYLSYIL 520
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 37.9 bits (84), Expect = 0.48
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL-TISGRKDQVEYLVQQNVIP 414
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 37.9 bits (84), Expect = 0.48
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL-TISGRKDQVEYLVQQNVIP 414
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 37.9 bits (84), Expect = 0.48
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL-TISGRKDQVEYLVQQNVIP 414
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 37.9 bits (84), Expect = 0.48
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL-TISGRKDQVEYLVQQNVIP 414
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 37.9 bits (84), Expect = 0.48
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL-TISGRKDQVEYLVQQNVIP 414
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 37.9 bits (84), Expect = 0.48
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL-TISGRKDQVEYLVQQNVIP 414
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 37.9 bits (84), Expect = 0.48
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL-TISGRKDQVEYLVQQNVIP 414
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 37.9 bits (84), Expect = 0.48
Identities = 42/176 (23%), Positives = 81/176 (46%), Gaps = 11/176 (6%)
Query: 1458 VKLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPS-IVPRLIEVLSDSHLR 1516
V+ +LPAL + + ++ L + +Q+ + S +VP L+ +LS ++
Sbjct: 240 VQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVK 299
Query: 1517 VQLSAAAALK--VIGS-----VIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVH 1569
VQ +A A+ V G+ V+ N ++ + P LL ++ NK + + +
Sbjct: 300 VQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQ 359
Query: 1570 FIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIP 1623
+ A A ++P++ T+K AA I N+ +++ +KD YL N+IP
Sbjct: 360 QVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNL-TISGRKDQVEYLVQQNVIP 414
>AK027783-1|BAB55365.1| 403|Homo sapiens protein ( Homo sapiens cDNA
FLJ14877 fis, clone PLACE1003044. ).
Length = 403
Score = 37.5 bits (83), Expect = 0.64
Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 8/126 (6%)
Query: 1461 VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSD--SHLRVQ 1518
++ AL + + + +T+ +L + P L+ +P +VP +I L+D S ++
Sbjct: 278 IVKALHKQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLK 337
Query: 1519 LSAAAALKVI----GSVIRNPEIQAIVPVLLQALQDPSNK--TSACLQTLLDTKFVHFID 1572
+ A + L VI + +P +QA+VP ++ + DP K + A L T K H +
Sbjct: 338 IDALSCLYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKAHHMPE 397
Query: 1573 APSLAL 1578
A L L
Sbjct: 398 AQWLRL 403
>AK091387-1|BAC03652.1| 509|Homo sapiens protein ( Homo sapiens cDNA
FLJ34068 fis, clone FCBBF3001918, highly similar to
SERINE/THREONINE PROTEIN PHOSPHATASE 2A, 65 KDA
REGULATORY ).
Length = 509
Score = 36.7 bits (81), Expect = 1.1
Identities = 40/220 (18%), Positives = 82/220 (37%), Gaps = 8/220 (3%)
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSVIR 1533
W + G + C P+ S+ + + SD V+ +AA+ L V+
Sbjct: 58 WWEAQSTCTACGLFSVCYPRVSSAVKAELRQYFRNLCSDDTPMVRRAAASKLGEFAKVLE 117
Query: 1534 NPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSL-ALIMPVVQRAFLDRST 1592
+++ + + L + L + L AL+MP +++A D+S
Sbjct: 118 LDNVKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSW 177
Query: 1593 ETRKMAAQIIGNMYSLTDQKDLTPYL--PNIIPGLKSSLLDPVPEVRSVSARALGAMVKG 1650
R M A + QK + P + +++P ++ + D EVR+ ++ + +
Sbjct: 178 RVRYMVADKFTEL-----QKAVGPEITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCEN 232
Query: 1651 MGESSFEELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGL 1690
+ E ++ + E S L+ V+ GL
Sbjct: 233 LSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGL 272
Score = 34.7 bits (76), Expect = 4.5
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 1756 INPILKALA-DENEYVRETALRAGQRIVNLYAESAI-ALLLPELEKGLFDDNWRIRY 1810
I P+ LA DE + VR A+ A I L + + AL++P L + D +WR+RY
Sbjct: 125 IIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRY 181
Score = 33.9 bits (74), Expect = 7.9
Identities = 48/280 (17%), Positives = 100/280 (35%), Gaps = 11/280 (3%)
Query: 1423 VLPHLLLCLGDGSQYVRTAADDTARLIMSRLSAHGVK-LVLPALLNAVNDDNWRTKAGSI 1481
++P D VR A + I L ++ LV+P L A D +WR +
Sbjct: 125 IIPMFSNLASDEQDSVRLLAVEACVNIAQLLPQEDLEALVMPTLRQAAEDKSWRVRYMVA 184
Query: 1482 ELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALK-----VIGSVIRNPE 1536
+ + +++ +VP ++ D V+ +A+ +K + N
Sbjct: 185 DKFTELQKAVGPEITK--TDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCRENVI 242
Query: 1537 IQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDRSTETRK 1596
+ I+P + + + D + + L +++ ++ ++P+ D E R
Sbjct: 243 MSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVR- 301
Query: 1597 MAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSF 1656
II N+ + + + +++P + D VR + + +G F
Sbjct: 302 --LNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFF 359
Query: 1657 EELLPWLMHTLTSETSSVDRSGAAQGLSEVVAGLGVQKLH 1696
+E L L + R A L ++V G + H
Sbjct: 360 DEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAH 399
>BC125109-1|AAI25110.1| 782|Homo sapiens Vac14 homolog (S.
cerevisiae) protein.
Length = 782
Score = 36.3 bits (80), Expect = 1.5
Identities = 43/179 (24%), Positives = 73/179 (40%), Gaps = 6/179 (3%)
Query: 1476 TKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRN- 1534
++ G + L A + K L ++ ++ +D+ R++ A AL I V R
Sbjct: 68 SRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGA 127
Query: 1535 --PEIQAIVPVL--LQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDR 1590
P + L L A DP+ K+ + L L V + L +P+++
Sbjct: 128 VLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVSFIPLLRERIYSN 187
Query: 1591 STETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVK 1649
+ R+ I + S+ D +L YLP I+ GL L D E+R + LG +K
Sbjct: 188 NQYARQFIISWILVLESVPDI-NLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLK 245
>BC125108-1|AAI25109.1| 782|Homo sapiens Vac14 homolog (S.
cerevisiae) protein.
Length = 782
Score = 36.3 bits (80), Expect = 1.5
Identities = 43/179 (24%), Positives = 73/179 (40%), Gaps = 6/179 (3%)
Query: 1476 TKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAAALKVIGSVIRN- 1534
++ G + L A + K L ++ ++ +D+ R++ A AL I V R
Sbjct: 68 SRKGGLIGLAACSIALGKDSGLYLKELIEPVLTCFNDADSRLRYYACEALYNIVKVARGA 127
Query: 1535 --PEIQAIVPVL--LQALQDPSNKTSACLQTLLDTKFVHFIDAPSLALIMPVVQRAFLDR 1590
P + L L A DP+ K+ + L L V + L +P+++
Sbjct: 128 VLPHFNVLFDGLSKLAADPDPNVKSGSELLDRLLKDIVTESNKFDLVSFIPLLRERIYSN 187
Query: 1591 STETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVK 1649
+ R+ I + S+ D +L YLP I+ GL L D E+R + LG +K
Sbjct: 188 NQYARQFIISWILVLESVPDI-NLLDYLPEILDGLFQILGDNGKEIRKMCEVVLGEFLK 245
>BX640725-1|CAE45842.1| 709|Homo sapiens hypothetical protein
protein.
Length = 709
Score = 35.9 bits (79), Expect = 2.0
Identities = 38/177 (21%), Positives = 76/177 (42%), Gaps = 10/177 (5%)
Query: 1459 KLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ 1518
K +L LL + D +A ++++L + P + + V + +E D H V
Sbjct: 516 KTILLLLLETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVV 575
Query: 1519 LSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLAL 1578
SA A V+ + I + ++ ++Q P N + +Q TK + + +L L
Sbjct: 576 RSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQ----TKVIERVSKETLNL 631
Query: 1579 IMPVVQRAFL---DRS-TETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLD 1631
++P + + D S + RK + ++++ +L P+L + G K LL+
Sbjct: 632 LLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGD-ELKPHLSQ-LTGSKMKLLN 686
>BC011530-1|AAH11530.1| 857|Homo sapiens Unknown (protein for
IMAGE:3874558) protein.
Length = 857
Score = 35.9 bits (79), Expect = 2.0
Identities = 38/177 (21%), Positives = 76/177 (42%), Gaps = 10/177 (5%)
Query: 1459 KLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ 1518
K +L LL + D +A ++++L + P + + V + +E D H V
Sbjct: 664 KTILLLLLETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVV 723
Query: 1519 LSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLAL 1578
SA A V+ + I + ++ ++Q P N + +Q TK + + +L L
Sbjct: 724 RSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQ----TKVIERVSKETLNL 779
Query: 1579 IMPVVQRAFL---DRS-TETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLD 1631
++P + + D S + RK + ++++ +L P+L + G K LL+
Sbjct: 780 LLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGD-ELKPHLSQ-LTGSKMKLLN 834
>AL137636-1|CAB70852.1| 356|Homo sapiens hypothetical protein
protein.
Length = 356
Score = 35.9 bits (79), Expect = 2.0
Identities = 38/177 (21%), Positives = 76/177 (42%), Gaps = 10/177 (5%)
Query: 1459 KLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ 1518
K +L LL + D +A ++++L + P + + V + +E D H V
Sbjct: 163 KTILLLLLETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVV 222
Query: 1519 LSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLAL 1578
SA A V+ + I + ++ ++Q P N + +Q TK + + +L L
Sbjct: 223 RSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQ----TKVIERVSKETLNL 278
Query: 1579 IMPVVQRAFL---DRS-TETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLD 1631
++P + + D S + RK + ++++ +L P+L + G K LL+
Sbjct: 279 LLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGD-ELKPHLSQ-LTGSKMKLLN 333
>AB014527-1|BAA31602.1| 1324|Homo sapiens KIAA0627 protein protein.
Length = 1324
Score = 35.9 bits (79), Expect = 2.0
Identities = 38/177 (21%), Positives = 76/177 (42%), Gaps = 10/177 (5%)
Query: 1459 KLVLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQ 1518
K +L LL + D +A ++++L + P + + V + +E D H V
Sbjct: 1131 KTILLLLLETLGDKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPHKEVV 1190
Query: 1519 LSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLDTKFVHFIDAPSLAL 1578
SA A V+ + I + ++ ++Q P N + +Q TK + + +L L
Sbjct: 1191 RSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQ----TKVIERVSKETLNL 1246
Query: 1579 IMPVVQRAFL---DRS-TETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPGLKSSLLD 1631
++P + + D S + RK + ++++ +L P+L + G K LL+
Sbjct: 1247 LLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGD-ELKPHLSQ-LTGSKMKLLN 1301
>CR456567-1|CAG30453.1| 348|Homo sapiens RTDR1 protein.
Length = 348
Score = 35.5 bits (78), Expect = 2.6
Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
Query: 352 KLTSSEDKIAVLNGVRALSQLAVAPEDRRALFAETAAHTARILDSESHER 401
+L S IA LN +AL+ LA APE R+AL +T T R ++ E++E+
Sbjct: 279 ELLHSPMTIARLNATKALTMLAEAPEGRKAL--QTHVPTFRAMEVETYEK 326
>BC117129-1|AAI17130.1| 1030|Homo sapiens MMS19-like (MET18 homolog,
S. cerevisiae) protein.
Length = 1030
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 233 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 287
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 288 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 337
>BC080532-1|AAH80532.1| 871|Homo sapiens MMS19L protein protein.
Length = 871
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 75 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 129
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 130 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 179
>BC008986-1|AAH08986.1| 348|Homo sapiens rhabdoid tumor deletion
region gene 1 protein.
Length = 348
Score = 35.5 bits (78), Expect = 2.6
Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
Query: 352 KLTSSEDKIAVLNGVRALSQLAVAPEDRRALFAETAAHTARILDSESHER 401
+L S IA LN +AL+ LA APE R+AL +T T R ++ E++E+
Sbjct: 279 ELLHSPMTIARLNATKALTMLAEAPEGRKAL--QTHVPTFRAMEVETYEK 326
>BC006575-1|AAH06575.2| 803|Homo sapiens MMS19L protein protein.
Length = 803
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 6 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 60
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 61 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 110
>AY974244-1|AAX59033.1| 1030|Homo sapiens MMS19-like (MET18 homolog,
S. cerevisiae) protein.
Length = 1030
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 233 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 287
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 288 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 337
>AL359388-1|CAI14189.1| 1030|Homo sapiens MMS19-like (MET18 homolog,
S. cerevisiae) protein.
Length = 1030
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 233 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 287
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 288 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 337
>AL355490-1|CAI40770.1| 1030|Homo sapiens MMS19-like (MET18 homolog,
S. cerevisiae) protein.
Length = 1030
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 233 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 287
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 288 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 337
>AJ306408-1|CAC29239.1| 1030|Homo sapiens MMS19 protein protein.
Length = 1030
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 233 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 287
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 288 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 337
>AF357881-1|AAK70402.1| 1030|Homo sapiens transcriptional coactivator
MMS19 protein.
Length = 1030
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 233 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 287
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 288 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 337
>AF319947-1|AAK52668.1| 1030|Homo sapiens MMS19 protein.
Length = 1030
Score = 35.5 bits (78), Expect = 2.6
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 233 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 287
Query: 1981 TIGNKALDDILPYMLEGLKDPDPAVADATLDGLKQASLR-IMSIKSRAVL 2029
G K L D LP + ++ A ++ A+L + + SR+VL
Sbjct: 288 VYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVL 337
>AF133587-1|AAF02484.1| 348|Homo sapiens rhabdoid tumor deletion
region protein 1 protein.
Length = 348
Score = 35.5 bits (78), Expect = 2.6
Identities = 21/50 (42%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
Query: 352 KLTSSEDKIAVLNGVRALSQLAVAPEDRRALFAETAAHTARILDSESHER 401
+L S IA LN +AL+ LA APE R+AL +T T R ++ E++E+
Sbjct: 279 ELLHSPMTIARLNATKALTMLAEAPEGRKAL--QTHVPTFRAMEVETYEK 326
>Z68228-1|CAA92522.1| 745|Homo sapiens plakoglobin protein.
Length = 745
Score = 35.1 bits (77), Expect = 3.4
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Query: 1421 VHVLPHLLLCLGDGSQYVRTAADD----TARLIMSRLSAHGVKLV--LPALLNAVNDDN- 1473
V L H +L GD A T+R + ++ + V+L +PA++ +N N
Sbjct: 435 VEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQ 494
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAA 1523
W +I L+ +A C +++PRL+++L +H Q AA
Sbjct: 495 WPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 544
>Y08890-1|CAA70103.1| 1097|Homo sapiens Ran_GTP binding protein 5
protein.
Length = 1097
Score = 35.1 bits (77), Expect = 3.4
Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 11/144 (7%)
Query: 1393 KNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQ-YVRT-AADDTARLIM 1450
+N RE AL F + G + Y+ + L+ C+ D +RT +A TA I+
Sbjct: 143 QNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFIL 202
Query: 1451 SRLSAHGVKL------VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVP 1504
+ + H V L +LP L AVND ++ ++ L +A PK L L + +
Sbjct: 203 A--NEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQ 260
Query: 1505 RLIEVLSDSHLRVQLSAAAALKVI 1528
+++ D+ L + AL+VI
Sbjct: 261 LSLKLCGDTSLN-NMQRQLALEVI 283
>M23410-1|AAA64895.1| 744|Homo sapiens Plakoglobin protein.
Length = 744
Score = 35.1 bits (77), Expect = 3.4
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Query: 1421 VHVLPHLLLCLGDGSQYVRTAADD----TARLIMSRLSAHGVKLV--LPALLNAVNDDN- 1473
V L H +L GD A T+R + ++ + V+L +PA++ +N N
Sbjct: 434 VEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQ 493
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAA 1523
W +I L+ +A C +++PRL+++L +H Q AA
Sbjct: 494 WPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 543
>BC045640-1|AAH45640.1| 1115|Homo sapiens RAN binding protein 5
protein.
Length = 1115
Score = 35.1 bits (77), Expect = 3.4
Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 11/144 (7%)
Query: 1393 KNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQ-YVRT-AADDTARLIM 1450
+N RE AL F + G + Y+ + L+ C+ D +RT +A TA I+
Sbjct: 161 QNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFIL 220
Query: 1451 SRLSAHGVKL------VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVP 1504
+ + H V L +LP L AVND ++ ++ L +A PK L L + +
Sbjct: 221 A--NEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQ 278
Query: 1505 RLIEVLSDSHLRVQLSAAAALKVI 1528
+++ D+ L + AL+VI
Sbjct: 279 LSLKLCGDTSLN-NMQRQLALEVI 301
>BC019309-1|AAH19309.1| 1097|Homo sapiens RANBP5 protein protein.
Length = 1097
Score = 35.1 bits (77), Expect = 3.4
Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 11/144 (7%)
Query: 1393 KNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQ-YVRT-AADDTARLIM 1450
+N RE AL F + G + Y+ + L+ C+ D +RT +A TA I+
Sbjct: 143 QNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFIL 202
Query: 1451 SRLSAHGVKL------VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVP 1504
+ + H V L +LP L AVND ++ ++ L +A PK L L + +
Sbjct: 203 A--NEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQ 260
Query: 1505 RLIEVLSDSHLRVQLSAAAALKVI 1528
+++ D+ L + AL+VI
Sbjct: 261 LSLKLCGDTSLN-NMQRQLALEVI 283
>BC011865-1|AAH11865.1| 745|Homo sapiens JUP protein protein.
Length = 745
Score = 35.1 bits (77), Expect = 3.4
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Query: 1421 VHVLPHLLLCLGDGSQYVRTAADD----TARLIMSRLSAHGVKLV--LPALLNAVNDDN- 1473
V L H +L GD A T+R + ++ + V+L +PA++ +N N
Sbjct: 435 VEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQ 494
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAA 1523
W +I L+ +A C +++PRL+++L +H Q AA
Sbjct: 495 WPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 544
>BC001497-1|AAH01497.1| 1097|Homo sapiens RANBP5 protein protein.
Length = 1097
Score = 35.1 bits (77), Expect = 3.4
Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 11/144 (7%)
Query: 1393 KNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQ-YVRT-AADDTARLIM 1450
+N RE AL F + G + Y+ + L+ C+ D +RT +A TA I+
Sbjct: 143 QNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFIL 202
Query: 1451 SRLSAHGVKL------VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVP 1504
+ + H V L +LP L AVND ++ ++ L +A PK L L + +
Sbjct: 203 A--NEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQ 260
Query: 1505 RLIEVLSDSHLRVQLSAAAALKVI 1528
+++ D+ L + AL+VI
Sbjct: 261 LSLKLCGDTSLN-NMQRQLALEVI 283
>BC000441-1|AAH00441.2| 784|Homo sapiens JUP protein protein.
Length = 784
Score = 35.1 bits (77), Expect = 3.4
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Query: 1421 VHVLPHLLLCLGDGSQYVRTAADD----TARLIMSRLSAHGVKLV--LPALLNAVNDDN- 1473
V L H +L GD A T+R + ++ + V+L +PA++ +N N
Sbjct: 474 VEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQ 533
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAA 1523
W +I L+ +A C +++PRL+++L +H Q AA
Sbjct: 534 WPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 583
>AY243535-1|AAO85780.1| 745|Homo sapiens gamma-catenin protein.
Length = 745
Score = 35.1 bits (77), Expect = 3.4
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Query: 1421 VHVLPHLLLCLGDGSQYVRTAADD----TARLIMSRLSAHGVKLV--LPALLNAVNDDN- 1473
V L H +L GD A T+R + ++ + V+L +PA++ +N N
Sbjct: 435 VEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQ 494
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAA 1523
W +I L+ +A C +++PRL+++L +H Q AA
Sbjct: 495 WPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 544
>AL356580-2|CAI13757.1| 1097|Homo sapiens RAN binding protein 5
protein.
Length = 1097
Score = 35.1 bits (77), Expect = 3.4
Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 11/144 (7%)
Query: 1393 KNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQ-YVRT-AADDTARLIM 1450
+N RE AL F + G + Y+ + L+ C+ D +RT +A TA I+
Sbjct: 143 QNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFIL 202
Query: 1451 SRLSAHGVKL------VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVP 1504
+ + H V L +LP L AVND ++ ++ L +A PK L L + +
Sbjct: 203 A--NEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQ 260
Query: 1505 RLIEVLSDSHLRVQLSAAAALKVI 1528
+++ D+ L + AL+VI
Sbjct: 261 LSLKLCGDTSLN-NMQRQLALEVI 283
>AL137120-1|CAI16520.1| 1097|Homo sapiens RAN binding protein 5
protein.
Length = 1097
Score = 35.1 bits (77), Expect = 3.4
Identities = 39/144 (27%), Positives = 65/144 (45%), Gaps = 11/144 (7%)
Query: 1393 KNYKYREGALFGFELLCRVLGRLFEPYIVHVLPHLLLCLGDGSQ-YVRT-AADDTARLIM 1450
+N RE AL F + G + Y+ + L+ C+ D +RT +A TA I+
Sbjct: 143 QNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFIL 202
Query: 1451 SRLSAHGVKL------VLPALLNAVNDDNWRTKAGSIELLGAMAYCAPKQLSSCLPSIVP 1504
+ + H V L +LP L AVND ++ ++ L +A PK L L + +
Sbjct: 203 A--NEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQ 260
Query: 1505 RLIEVLSDSHLRVQLSAAAALKVI 1528
+++ D+ L + AL+VI
Sbjct: 261 LSLKLCGDTSLN-NMQRQLALEVI 283
>AF306723-1|AAG16727.1| 745|Homo sapiens plakoglobin protein.
Length = 745
Score = 35.1 bits (77), Expect = 3.4
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 7/110 (6%)
Query: 1421 VHVLPHLLLCLGDGSQYVRTAADD----TARLIMSRLSAHGVKLV--LPALLNAVNDDN- 1473
V L H +L GD A T+R + ++ + V+L +PA++ +N N
Sbjct: 435 VEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQ 494
Query: 1474 WRTKAGSIELLGAMAYCAPKQLSSCLPSIVPRLIEVLSDSHLRVQLSAAA 1523
W +I L+ +A C +++PRL+++L +H Q AA
Sbjct: 495 WPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAA 544
>BC032563-1|AAH32563.1| 149|Homo sapiens CLASP1 protein protein.
Length = 149
Score = 34.7 bits (76), Expect = 4.5
Identities = 29/127 (22%), Positives = 56/127 (44%), Gaps = 2/127 (1%)
Query: 1505 RLIEVLSDSHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLD 1564
+ +E DSH V +A A + S I + ++ ++Q P N + +QT +
Sbjct: 2 KTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVV 61
Query: 1565 TKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPG 1624
+ L I+P + + + + + RK + + +YS+ + DL P+L + G
Sbjct: 62 ERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGE-DLKPHLAQ-LTG 119
Query: 1625 LKSSLLD 1631
K LL+
Sbjct: 120 SKMKLLN 126
>BC021127-1|AAH21127.1| 519|Homo sapiens KIAA0368 protein protein.
Length = 519
Score = 34.7 bits (76), Expect = 4.5
Identities = 22/56 (39%), Positives = 32/56 (57%), Gaps = 2/56 (3%)
Query: 1607 SLTDQ--KDLTPYLPNIIPGLKSSLLDPVPEVRSVSARALGAMVKGMGESSFEELL 1660
SLT Q +DLTPY ++ L S L D ++ A A+G +V+ +SS E+LL
Sbjct: 59 SLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHLVRTSRDSSTEKLL 114
Score = 33.9 bits (74), Expect = 7.9
Identities = 17/76 (22%), Positives = 36/76 (47%)
Query: 1722 RTDIAPHVKDGYIMMFIYMPGAFTDEFTPYIGQIINPILKALADENEYVRETALRAGQRI 1781
R+ + K G + + + + TPY G++++ +L L D N ++++ A +
Sbjct: 42 RSGVGLGTKGGCASVIVSLTTQCPQDLTPYSGKLMSALLSGLTDRNSVIQKSCAFAMGHL 101
Query: 1782 VNLYAESAIALLLPEL 1797
V +S+ LL +L
Sbjct: 102 VRTSRDSSTEKLLQKL 117
>AL355490-23|CAI40792.1| 885|Homo sapiens MMS19-like (MET18 homolog,
S. cerevisiae) protein.
Length = 885
Score = 34.7 bits (76), Expect = 4.5
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 186 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 240
Query: 1981 TIGNKALDDILPYMLEGLK 1999
G K L D LP + ++
Sbjct: 241 VYGQKELKDFLPSLWASIR 259
>AK027710-1|BAB55315.1| 774|Homo sapiens protein ( Homo sapiens cDNA
FLJ14804 fis, clone NT2RP4001638, weakly similar to DNA
REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19. ).
Length = 774
Score = 34.7 bits (76), Expect = 4.5
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 1921 PRADQRQGVCIGLGEILASTSRDAVLSFADGLVPTVRTALCDPLPEVRLAAARTFDSLHA 1980
P QR+ + + L +LAST R FA+ L+P + + + +L + +T ++ A
Sbjct: 75 PHGIQREDLILSLRAVLASTPR-----FAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCA 129
Query: 1981 TIGNKALDDILPYMLEGLK 1999
G K L D LP + ++
Sbjct: 130 VYGQKELKDFLPSLWASIR 148
>AC013399-2|AAX88872.1| 149|Homo sapiens unknown protein.
Length = 149
Score = 34.7 bits (76), Expect = 4.5
Identities = 29/127 (22%), Positives = 56/127 (44%), Gaps = 2/127 (1%)
Query: 1505 RLIEVLSDSHLRVQLSAAAALKVIGSVIRNPEIQAIVPVLLQALQDPSNKTSACLQTLLD 1564
+ +E DSH V +A A + S I + ++ ++Q P N + +QT +
Sbjct: 2 KTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVV 61
Query: 1565 TKFVHFIDAPSLALIMPVVQRAFLDRSTETRKMAAQIIGNMYSLTDQKDLTPYLPNIIPG 1624
+ L I+P + + + + + RK + + +YS+ + DL P+L + G
Sbjct: 62 ERIAKESLLQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGE-DLKPHLAQ-LTG 119
Query: 1625 LKSSLLD 1631
K LL+
Sbjct: 120 SKMKLLN 126
>U02325-1|AAA19950.1| 350|Homo sapiens neu differentiation factor
protein.
Length = 350
Score = 33.9 bits (74), Expect = 7.9
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 1266 SLARHLE--PDDVRLRPIALRLVAALSTPAQQVPHP-HITSLSVAASSGCRPSVQEAVGN 1322
S RH PD R P + R V+A++TPA+ P H S + S P V +
Sbjct: 218 SFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVS 277
Query: 1323 CLPHLVTSPALESEIP 1338
+P + SP +E E P
Sbjct: 278 -MPSMAVSPFMEEERP 292
>M94166-1|AAA58639.1| 645|Homo sapiens heregulin-beta1 protein.
Length = 645
Score = 33.9 bits (74), Expect = 7.9
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 1266 SLARHLE--PDDVRLRPIALRLVAALSTPAQQVPHP-HITSLSVAASSGCRPSVQEAVGN 1322
S RH PD R P + R V+A++TPA+ P H S + S P V +
Sbjct: 408 SFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVS 467
Query: 1323 CLPHLVTSPALESEIP 1338
+P + SP +E E P
Sbjct: 468 -MPSMAVSPFMEEERP 482
>M94165-1|AAA58638.1| 640|Homo sapiens heregulin-alpha protein.
Length = 640
Score = 33.9 bits (74), Expect = 7.9
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 4/76 (5%)
Query: 1266 SLARHLE--PDDVRLRPIALRLVAALSTPAQQVPHP-HITSLSVAASSGCRPSVQEAVGN 1322
S RH PD R P + R V+A++TPA+ P H S + S P V +
Sbjct: 403 SFLRHARETPDSYRDSPHSERYVSAMTTPARMSPVDFHTPSSPKSPPSEMSPPVSSMTVS 462
Query: 1323 CLPHLVTSPALESEIP 1338
+P + SP +E E P
Sbjct: 463 -MPSMAVSPFMEEERP 477
>BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 33.9 bits (74), Expect = 7.9
Identities = 19/60 (31%), Positives = 29/60 (48%)
Query: 1335 SEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKN 1394
+E G+ NKL L+ F D R A YG+ + + + L Q + L E +Q+ KN
Sbjct: 667 TEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKN 726
>BC063519-1|AAH63519.1| 613|Homo sapiens PHLPP protein protein.
Length = 613
Score = 33.9 bits (74), Expect = 7.9
Identities = 19/60 (31%), Positives = 29/60 (48%)
Query: 1335 SEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKN 1394
+E G+ NKL L+ F D R A YG+ + + + L Q + L E +Q+ KN
Sbjct: 76 TEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKN 135
>BC047653-1|AAH47653.1| 656|Homo sapiens PHLPP protein protein.
Length = 656
Score = 33.9 bits (74), Expect = 7.9
Identities = 19/60 (31%), Positives = 29/60 (48%)
Query: 1335 SEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKN 1394
+E G+ NKL L+ F D R A YG+ + + + L Q + L E +Q+ KN
Sbjct: 118 TEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKN 177
>BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 33.9 bits (74), Expect = 7.9
Identities = 19/60 (31%), Positives = 29/60 (48%)
Query: 1335 SEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKN 1394
+E G+ NKL L+ F D R A YG+ + + + L Q + L E +Q+ KN
Sbjct: 667 TEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKN 726
>BC010706-1|AAH10706.1| 543|Homo sapiens PHLPP protein protein.
Length = 543
Score = 33.9 bits (74), Expect = 7.9
Identities = 19/60 (31%), Positives = 29/60 (48%)
Query: 1335 SEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKN 1394
+E G+ NKL L+ F D R A YG+ + + + L Q + L E +Q+ KN
Sbjct: 5 TEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKN 64
>AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein.
Length = 1369
Score = 33.9 bits (74), Expect = 7.9
Identities = 19/60 (31%), Positives = 29/60 (48%)
Query: 1335 SEIPGIVNKLMKQLLTAEKFGDRRGAAYGIAGVVKGLGILSLKQLDIMGKLTEAIQEKKN 1394
+E G+ NKL L+ F D R A YG+ + + + L Q + L E +Q+ KN
Sbjct: 831 TEASGVKNKLCVAALSVNNFCDNREALYGVFDGDRNVEVPYLLQCTMSDILAEELQKTKN 890
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.319 0.134 0.388
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 331,364,798
Number of Sequences: 224733
Number of extensions: 12886420
Number of successful extensions: 38765
Number of sequences better than 10.0: 112
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 37988
Number of HSP's gapped (non-prelim): 737
length of query: 2615
length of database: 73,234,838
effective HSP length: 103
effective length of query: 2512
effective length of database: 50,087,339
effective search space: 125819395568
effective search space used: 125819395568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 74 (33.9 bits)
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