Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002837-TA|BGIBMGA002837-PA|IPR001680|WD-40 repeat,
IPR013915|Pre-mRNA-splicing factor 19, IPR011046|WD40-like,
IPR003613|U box
(497 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 660 0.0
BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 660 0.0
BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 660 0.0
AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein ... 660 0.0
CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein. 122 3e-27
BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80 (WD40-conta... 122 3e-27
BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat ... 122 3e-27
BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processin... 118 5e-26
BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processin... 118 5e-26
AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6 snRNP-spec... 118 5e-26
AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processin... 118 5e-26
AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processin... 118 5e-26
AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit pro... 118 5e-26
AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear rib... 118 5e-26
AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant p... 118 5e-26
CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein. 118 6e-26
AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa prot... 115 3e-25
U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p... 113 1e-24
AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymeras... 105 4e-22
AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription ... 105 4e-22
AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor ... 105 4e-22
BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69 pro... 105 5e-22
AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens ... 105 5e-22
AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein. 105 5e-22
X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein. 104 8e-22
U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100 pr... 104 8e-22
U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor pro... 104 8e-22
BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,... 104 8e-22
AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,... 104 8e-22
AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiatio... 104 8e-22
AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens ... 104 8e-22
BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein. 103 1e-21
BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A pr... 103 1e-21
BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein. 103 1e-21
BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein. 103 1e-21
AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens ... 102 3e-21
EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein. 101 4e-21
BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B pr... 101 4e-21
AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens ... 101 4e-21
CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein. 95 4e-19
BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B pro... 95 4e-19
AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens ... 95 4e-19
BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5 prot... 93 2e-18
BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5 prot... 93 2e-18
AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens ... 93 2e-18
AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein pr... 93 2e-18
AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens ... 92 4e-18
BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical... 91 1e-17
AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD rep... 89 3e-17
AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein. 89 3e-17
BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein. 87 1e-16
AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38 pro... 87 1e-16
U72342-1|AAC51111.1| 410|Homo sapiens platelet activating facto... 87 2e-16
L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencepha... 87 2e-16
L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencepha... 87 2e-16
BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating fac... 87 2e-16
AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating fac... 87 2e-16
AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker lissencep... 87 2e-16
EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein. 86 2e-16
BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5... 86 2e-16
AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5... 86 2e-16
AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein. 86 3e-16
AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein. 86 3e-16
L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencepha... 85 7e-16
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein. 84 1e-15
BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein. 84 1e-15
AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein comple... 84 1e-15
AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein comple... 84 1e-15
AL445230-2|CAI15005.1| 1224|Homo sapiens coatomer protein comple... 84 1e-15
AL445230-1|CAI15004.1| 1233|Homo sapiens coatomer protein comple... 84 1e-15
AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kD... 84 1e-15
BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat dom... 83 2e-15
BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat dom... 83 2e-15
AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4 prot... 83 2e-15
AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7 prot... 83 2e-15
AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10 pro... 83 2e-15
AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isof... 83 2e-15
AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens ... 83 2e-15
AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form p... 83 2e-15
AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form ... 83 2e-15
AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30 pro... 83 2e-15
AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor p... 83 2e-15
AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isof... 83 2e-15
BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1... 83 3e-15
BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein. 83 3e-15
AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1... 83 3e-15
BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein. 82 4e-15
BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein. 82 4e-15
BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein. 82 4e-15
BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein. 82 5e-15
X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein. 81 7e-15
U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan prote... 81 7e-15
U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan prote... 81 7e-15
U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein. 81 7e-15
BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein. 81 7e-15
BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptopha... 81 7e-15
BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptopha... 81 7e-15
AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan pro... 81 7e-15
AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens ... 81 7e-15
AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein. 81 7e-15
AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker lissencep... 81 9e-15
BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide bind... 80 2e-14
BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide bind... 80 2e-14
BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide bind... 80 2e-14
Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-bindin... 79 5e-14
U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain pr... 79 5e-14
M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein. 79 5e-14
AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide bind... 79 5e-14
AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide bind... 79 5e-14
AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-bind... 79 5e-14
X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRN... 78 6e-14
M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transduci... 78 6e-14
CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein. 78 6e-14
BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide bind... 78 6e-14
BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide bind... 78 6e-14
BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide bind... 78 6e-14
BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide bind... 78 6e-14
AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide bind... 78 6e-14
AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide bin... 78 6e-14
AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide bind... 78 6e-14
AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide bind... 78 6e-14
AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal tra... 78 6e-14
M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transduci... 78 8e-14
M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein. 78 8e-14
CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein. 78 8e-14
BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein. 78 8e-14
BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide bind... 78 8e-14
BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide bind... 78 8e-14
BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide bind... 78 8e-14
BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide bind... 78 8e-14
AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide bind... 78 8e-14
AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide bind... 78 8e-14
AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein. 78 8e-14
M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human signal-tr... 76 3e-13
BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48 pro... 75 4e-13
AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal pro... 75 4e-13
AB209438-1|BAD92675.1| 316|Homo sapiens PWP2 periodic tryptopha... 75 4e-13
AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein. 75 4e-13
U05340-1|AAA19017.1| 499|Homo sapiens p55CDC protein. 75 6e-13
DQ473545-1|ABE96834.1| 499|Homo sapiens CDC20 cell division cyc... 75 6e-13
BT007388-1|AAP36052.1| 499|Homo sapiens CDC20 cell division cyc... 75 6e-13
BC110321-1|AAI10322.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC031294-1|AAH31294.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC024257-1|AAH24257.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC015998-1|AAH15998.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC013303-1|AAH13303.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC012827-1|AAH12827.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC012803-1|AAH12803.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC010044-1|AAH10044.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC009426-1|AAH09426.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC009425-1|AAH09425.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC006272-1|AAH06272.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC001088-1|AAH01088.1| 499|Homo sapiens cell division cycle 20 ... 75 6e-13
BC000624-1|AAH00624.1| 499|Homo sapiens CDC20 protein protein. 75 6e-13
AL139289-3|CAB92757.1| 499|Homo sapiens CDC20 cell division cyc... 75 6e-13
AF099644-1|AAD16405.1| 499|Homo sapiens cell cycle protein CDC2... 75 6e-13
M95627-1|AAA68889.1| 452|Homo sapiens angio-associated migrator... 75 8e-13
CR456755-1|CAG33036.1| 452|Homo sapiens AAMP protein. 75 8e-13
BC039866-1|AAH39866.2| 434|Homo sapiens angio-associated, migra... 75 8e-13
BC020244-1|AAH20244.1| 429|Homo sapiens Similar to angio-associ... 75 8e-13
AL163279-2|CAB90452.1| 2295|Homo sapiens homolog to cAMP respons... 75 8e-13
AJ292466-1|CAC44372.1| 2269|Homo sapiens WDR9 protein, form B p... 75 8e-13
AJ292465-1|CAC44371.1| 2320|Homo sapiens WDR9 protein, form A pr... 75 8e-13
AJ238214-1|CAC37033.2| 2269|Homo sapiens hypothetical protein pr... 75 8e-13
AB080587-1|BAD74072.1| 2199|Homo sapiens WD repeat protein WDR9-... 75 8e-13
AB080586-1|BAD74071.1| 2269|Homo sapiens WD repeat protein protein. 75 8e-13
L02547-1|AAA35691.1| 431|Homo sapiens cleavage stimulation fact... 74 1e-12
BT007138-1|AAP35802.1| 431|Homo sapiens cleavage stimulation fa... 74 1e-12
BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61 pro... 74 1e-12
BC007425-1|AAH07425.1| 431|Homo sapiens cleavage stimulation fa... 74 1e-12
BC001011-1|AAH01011.1| 431|Homo sapiens cleavage stimulation fa... 74 1e-12
AL121914-12|CAI19328.1| 431|Homo sapiens cleavage stimulation f... 74 1e-12
AL121914-11|CAC12718.2| 345|Homo sapiens cleavage stimulation f... 74 1e-12
AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens ... 74 1e-12
AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination p... 74 1e-12
AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta subunit-... 74 1e-12
BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein. 73 2e-12
AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repe... 73 2e-12
AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repe... 73 2e-12
AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repe... 73 2e-12
AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repe... 73 2e-12
AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repe... 73 2e-12
CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein. 73 2e-12
M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.... 71 7e-12
EF011612-1|ABK41102.1| 514|Homo sapiens CDW2/WDR26 protein. 71 7e-12
CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein. 71 7e-12
CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein. 71 7e-12
BC063817-1|AAH63817.1| 404|Homo sapiens WDR26 protein protein. 71 7e-12
BC052301-1|AAH52301.2| 514|Homo sapiens WD repeat domain 26 pro... 71 7e-12
BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC031471-1|AAH31471.2| 373|Homo sapiens WDR26 protein protein. 71 7e-12
BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide bind... 71 7e-12
AY304473-1|AAQ74770.1| 514|Homo sapiens WD40 repeat protein 26 ... 71 7e-12
AY221751-1|AAO67709.1| 498|Homo sapiens myocardial ischemic pre... 71 7e-12
AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7 ... 71 7e-12
AK024669-1|BAB14955.1| 367|Homo sapiens protein ( Homo sapiens ... 71 7e-12
AB209887-1|BAD93124.1| 725|Homo sapiens WD repeat domain 26 var... 71 7e-12
BC012352-1|AAH12352.1| 366|Homo sapiens WDR31 protein protein. 71 9e-12
BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated prote... 71 9e-12
AL449305-1|CAI10961.1| 367|Homo sapiens WD repeat domain 31 pro... 71 9e-12
AL137066-1|CAH70096.1| 367|Homo sapiens WD repeat domain 31 pro... 71 9e-12
AK093240-1|BAC04106.1| 367|Homo sapiens protein ( Homo sapiens ... 71 9e-12
BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein... 70 2e-11
BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein... 70 2e-11
BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase... 70 2e-11
BC021905-1|AAH21905.1| 896|Homo sapiens Unknown (protein for IM... 70 2e-11
BC000162-1|AAH00162.1| 350|Homo sapiens serine/threonine kinase... 70 2e-11
AY049776-1|AAL15433.1| 350|Homo sapiens unr-interacting protein... 70 2e-11
AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( Human DNA seq... 70 2e-11
AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA seq... 70 2e-11
AK057039-1|BAB71353.1| 912|Homo sapiens protein ( Homo sapiens ... 70 2e-11
AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11 pro... 70 2e-11
AJ010025-1|CAB38041.1| 350|Homo sapiens unr-interacting protein... 70 2e-11
AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein. 70 2e-11
AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein. 70 2e-11
AB024327-1|BAA75544.1| 350|Homo sapiens WD-40 repeat protein pr... 70 2e-11
AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide bind... 70 2e-11
AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta subunit-... 70 2e-11
AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated prote... 69 3e-11
AK095312-1|BAC04527.1| 895|Homo sapiens protein ( Homo sapiens ... 69 3e-11
BC133025-1|AAI33026.1| 951|Homo sapiens WD repeat domain 36 pro... 69 4e-11
AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating fac... 69 4e-11
AF385437-1|AAM43838.1| 951|Homo sapiens T-cell activation WD re... 69 4e-11
BC108280-1|AAI08281.1| 896|Homo sapiens echinoderm microtubule ... 69 5e-11
BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS box-... 69 5e-11
AK128679-1|BAC87566.1| 780|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AK093146-1|BAC04073.1| 889|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein. 69 5e-11
AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD ... 69 5e-11
AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein. 69 5e-11
AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog ... 68 7e-11
BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat dom... 68 9e-11
BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein. 68 9e-11
BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1 (Dr... 68 9e-11
BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein. 68 9e-11
AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing ... 68 9e-11
AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1 i... 68 9e-11
AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens ... 68 9e-11
AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease acti... 68 9e-11
AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease acti... 68 9e-11
AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease acti... 68 9e-11
AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease acti... 68 9e-11
AF176022-1|AAF04528.1| 542|Homo sapiens F-box protein Fbw1b pro... 68 9e-11
AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease acti... 68 9e-11
AB033281-1|BAA92331.1| 542|Homo sapiens F-box and WD-repeats pr... 68 9e-11
AB033280-1|BAA92330.1| 529|Homo sapiens F-box and WD-repeats pr... 68 9e-11
AB033279-1|BAA92329.1| 508|Homo sapiens F-box and WD-repeats pr... 68 9e-11
AB014596-1|BAA31671.1| 550|Homo sapiens KIAA0696 protein protein. 68 9e-11
Y14153-1|CAA74572.1| 569|Homo sapiens beta-transducin repeats c... 67 2e-10
BC027994-1|AAH27994.1| 605|Homo sapiens beta-transducin repeat ... 67 2e-10
BC025392-1|AAH25392.1| 620|Homo sapiens WD repeat domain 16 pro... 67 2e-10
AL627424-18|CAI41043.1| 569|Homo sapiens beta-transducin repeat... 67 2e-10
AL627424-17|CAI41042.1| 605|Homo sapiens beta-transducin repeat... 67 2e-10
AL445463-3|CAI12964.1| 569|Homo sapiens beta-transducin repeat ... 67 2e-10
AL445463-2|CAI12963.1| 605|Homo sapiens beta-transducin repeat ... 67 2e-10
AL133387-2|CAH70019.1| 569|Homo sapiens beta-transducin repeat ... 67 2e-10
AL133387-1|CAH70020.1| 605|Homo sapiens beta-transducin repeat ... 67 2e-10
AK094847-1|BAC04435.1| 630|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AK074435-1|BAB85083.1| 412|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AK022227-1|BAB13990.1| 217|Homo sapiens protein ( Homo sapiens ... 67 2e-10
AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease acti... 67 2e-10
AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease acti... 67 2e-10
AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease acti... 67 2e-10
AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease acti... 67 2e-10
AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease acti... 67 2e-10
AF129530-1|AAF04464.1| 569|Homo sapiens F-box protein Fbw1A pro... 67 2e-10
AF101784-1|AAD08702.1| 605|Homo sapiens b-TRCP variant E3RS-Ika... 67 2e-10
AB065281-1|BAB83743.1| 620|Homo sapiens WDR16 protein. 67 2e-10
AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein. 67 2e-10
BC013997-1|AAH13997.1| 353|Homo sapiens guanine nucleotide bind... 66 2e-10
AF501885-1|AAM15921.1| 353|Homo sapiens guanine nucleotide bind... 66 2e-10
AF300650-1|AAG18444.1| 395|Homo sapiens guanine nucleotide bind... 66 2e-10
AF017656-1|AAC63826.1| 353|Homo sapiens G protein beta 5 subuni... 66 2e-10
AB209669-1|BAD92906.1| 1903|Homo sapiens Telomerase protein comp... 66 2e-10
Z92544-1|CAM26347.1| 790|Homo sapiens WD repeat domain 24 protein. 66 3e-10
DQ120664-1|ABB92447.1| 456|Homo sapiens rcCDC20 protein. 66 3e-10
BC009761-1|AAH09761.2| 718|Homo sapiens WDR24 protein protein. 66 3e-10
BC008025-1|AAH08025.1| 790|Homo sapiens WD repeat domain 24 pro... 66 3e-10
AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease acti... 66 3e-10
AJ223814-1|CAA11560.1| 780|Homo sapiens striatin protein. 66 3e-10
X70476-1|CAA49900.1| 906|Homo sapiens subunit of coatomer compl... 66 4e-10
U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated pro... 66 4e-10
BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated p... 66 4e-10
BC106879-1|AAI06880.1| 731|Homo sapiens STRN protein protein. 66 4e-10
BC106878-1|AAI06879.1| 755|Homo sapiens STRN protein protein. 66 4e-10
BC035409-1|AAH35409.1| 808|Homo sapiens transducin (beta)-like ... 66 4e-10
BC026067-1|AAH26067.2| 464|Homo sapiens WDSOF1 protein protein. 66 4e-10
BC014007-1|AAH14007.1| 808|Homo sapiens TBL3 protein protein. 66 4e-10
BC010231-1|AAH10231.1| 808|Homo sapiens transducin (beta)-like ... 66 4e-10
BC000326-1|AAH00326.1| 906|Homo sapiens coatomer protein comple... 66 4e-10
AC007382-1|AAF66162.1| 616|Homo sapiens unknown protein. 66 4e-10
AB209173-1|BAD92410.1| 832|Homo sapiens transducin beta-like 3 ... 66 4e-10
AK074217-1|BAB85020.1| 506|Homo sapiens protein ( Homo sapiens ... 65 5e-10
AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease acti... 65 6e-10
AF106683-1|AAD43036.1| 421|Homo sapiens WSB-1 protein. 65 6e-10
BC126114-1|AAI26115.1| 579|Homo sapiens cell division cycle 40 ... 64 8e-10
BC117145-1|AAI17146.1| 579|Homo sapiens cell division cycle 40 ... 64 8e-10
BC112042-1|AAI12043.1| 597|Homo sapiens WD repeats and SOF1 dom... 64 8e-10
BC107125-1|AAI07126.1| 248|Homo sapiens WDR86 protein protein. 64 8e-10
BC101810-1|AAI01811.1| 597|Homo sapiens WD repeats and SOF1 dom... 64 8e-10
BC047921-1|AAH47921.1| 563|Homo sapiens WDR86 protein protein. 64 8e-10
AL671518-2|CAI13322.1| 579|Homo sapiens cell division cycle 40 ... 64 8e-10
AK222721-1|BAD96441.1| 579|Homo sapiens pre-mRNA splicing facto... 64 8e-10
AK027799-1|BAB55377.1| 597|Homo sapiens protein ( Homo sapiens ... 64 8e-10
AK001874-1|BAA91955.1| 445|Homo sapiens protein ( Homo sapiens ... 64 8e-10
AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease acti... 64 8e-10
AF061241-1|AAC25166.1| 542|Homo sapiens splicing factor hPRP17 ... 64 8e-10
AF038392-1|AAC39730.1| 579|Homo sapiens pre-mRNA splicing facto... 64 8e-10
BC007620-1|AAH07620.1| 570|Homo sapiens TBL3 protein protein. 64 1e-09
AK074725-1|BAC11163.1| 597|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AL671518-1|CAI13321.1| 539|Homo sapiens cell division cycle 40 ... 63 2e-09
AL445068-1|CAI22519.1| 539|Homo sapiens cell division cycle 40 ... 63 2e-09
AB208903-1|BAD92140.1| 501|Homo sapiens pre-mRNA splicing facto... 63 2e-09
U67615-1|AAB41309.1| 3801|Homo sapiens beige protein homolog pro... 63 3e-09
AL390765-1|CAI14952.1| 3801|Homo sapiens lysosomal trafficking r... 63 3e-09
AL121997-1|CAI18987.1| 3801|Homo sapiens lysosomal trafficking r... 63 3e-09
Y12781-1|CAA73319.1| 577|Homo sapiens transducin (beta) like 1 ... 62 3e-09
BC052304-1|AAH52304.1| 577|Homo sapiens transducin (beta)-like ... 62 3e-09
BC032708-1|AAH32708.1| 526|Homo sapiens TBL1X protein protein. 62 3e-09
AF268193-1|AAG44736.1| 514|Homo sapiens IRA1 protein. 62 3e-09
AB209608-1|BAD92845.1| 540|Homo sapiens transducin beta-like 1X... 62 3e-09
X96586-1|CAA65405.1| 917|Homo sapiens FAN protein protein. 62 4e-09
U17989-1|AAB81551.1| 713|Homo sapiens GS2NA protein. 62 4e-09
BC132673-1|AAI32674.1| 713|Homo sapiens striatin, calmodulin bi... 62 4e-09
BC126221-1|AAI26222.1| 713|Homo sapiens striatin, calmodulin bi... 62 4e-09
BC113421-1|AAI13422.1| 514|Homo sapiens transducin (beta)-like ... 62 4e-09
BC041124-1|AAH41124.1| 917|Homo sapiens neutral sphingomyelinas... 62 4e-09
AK074891-1|BAC11271.1| 242|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AK022956-1|BAB14331.1| 514|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AF314544-1|AAK00301.1| 514|Homo sapiens nuclear receptor co-rep... 62 4e-09
AF243424-1|AAF81201.1| 678|Homo sapiens SG2NA beta isoform prot... 62 4e-09
AK222501-1|BAD96221.1| 392|Homo sapiens hypothetical protein FL... 62 6e-09
AK093494-1|BAC04184.1| 476|Homo sapiens protein ( Homo sapiens ... 62 6e-09
EF011613-1|ABK41103.1| 513|Homo sapiens CDW3/SMU1 protein. 61 8e-09
BC110654-1|AAI10655.1| 513|Homo sapiens smu-1 suppressor of mec... 61 8e-09
BC002876-1|AAH02876.1| 513|Homo sapiens smu-1 suppressor of mec... 61 8e-09
AL162590-6|CAI15554.1| 513|Homo sapiens smu-1 suppressor of mec... 61 8e-09
AK001667-1|BAA91822.1| 513|Homo sapiens protein ( Homo sapiens ... 61 8e-09
BC028628-1|AAH28628.1| 375|Homo sapiens WDR71 protein protein. 61 1e-08
BC021541-1|AAH21541.1| 392|Homo sapiens WD repeat domain 71 pro... 61 1e-08
BC006142-1|AAH06142.2| 392|Homo sapiens WD repeat domain 71 pro... 61 1e-08
AK123876-1|BAC85713.1| 428|Homo sapiens protein ( Homo sapiens ... 61 1e-08
AK021910-1|BAB13933.1| 392|Homo sapiens protein ( Homo sapiens ... 61 1e-08
AF087895-1|AAP97194.1| 375|Homo sapiens G-16 protein. 61 1e-08
X89887-1|CAA61979.1| 1017|Homo sapiens HIRA protein. 60 2e-08
X81844-1|CAA57436.1| 1017|Homo sapiens HIRA protein. 60 2e-08
X77633-1|CAA54721.1| 973|Homo sapiens HIRAHs protein. 60 2e-08
X75296-1|CAA53044.1| 766|Homo sapiens TUP1 like enhancer of SPL... 60 2e-08
EF079890-1|ABN48555.1| 444|Homo sapiens ATG16 autophagy related... 60 2e-08
EF079889-1|ABN48554.1| 588|Homo sapiens ATG16 autophagy related... 60 2e-08
CR456503-1|CAG30389.1| 1017|Homo sapiens HIRA protein. 60 2e-08
BC117337-1|AAI17338.1| 523|Homo sapiens ATG16L1 protein protein. 60 2e-08
BC071846-1|AAH71846.1| 475|Homo sapiens ATG16L1 protein protein. 60 2e-08
BC039835-1|AAH39835.1| 1017|Homo sapiens HIR histone cell cycle ... 60 2e-08
BC032721-1|AAH32721.1| 643|Homo sapiens Unknown (protein for IM... 60 2e-08
AY398617-1|AAR32130.1| 607|Homo sapiens APG16L beta protein. 60 2e-08
AC013726-3|AAY14860.1| 523|Homo sapiens unknown protein. 60 2e-08
U63810-1|AAC24948.1| 339|Homo sapiens WD40 protein Ciao 1 protein. 60 2e-08
EF011618-1|ABK41108.1| 339|Homo sapiens CDW8/WDR39 protein. 60 2e-08
CR456802-1|CAG33083.1| 339|Homo sapiens CIAO1 protein. 60 2e-08
BC063041-1|AAH63041.1| 1129|Homo sapiens WD repeat and HMG-box D... 60 2e-08
BC043349-1|AAH43349.1| 612|Homo sapiens WDHD1 protein protein. 60 2e-08
BC032812-1|AAH32812.1| 339|Homo sapiens cytosolic iron-sulfur p... 60 2e-08
BC005040-1|AAH05040.1| 613|Homo sapiens Unknown (protein for IM... 60 2e-08
BC001395-1|AAH01395.1| 339|Homo sapiens cytosolic iron-sulfur p... 60 2e-08
BC000622-1|AAH00622.1| 613|Homo sapiens WDHD1 protein protein. 60 2e-08
AK223257-1|BAD96977.1| 339|Homo sapiens WD40 protein Ciao1 vari... 60 2e-08
AJ006266-1|CAA06932.1| 1129|Homo sapiens AND-1 protein protein. 60 2e-08
AC004020-1|AAC23493.1| 339|Homo sapiens Unknown gene product pr... 60 2e-08
BX538087-1|CAD98010.1| 913|Homo sapiens hypothetical protein pr... 59 3e-08
BX537578-1|CAD97788.1| 913|Homo sapiens hypothetical protein pr... 59 3e-08
BC028697-1|AAH28697.3| 913|Homo sapiens WD repeat domain 44 pro... 59 3e-08
AL834210-1|CAD38894.1| 805|Homo sapiens hypothetical protein pr... 59 3e-08
AL391830-1|CAI41512.1| 913|Homo sapiens WD repeat domain 44 pro... 59 3e-08
AL391803-2|CAI41482.1| 913|Homo sapiens WD repeat domain 44 pro... 59 3e-08
AL391803-1|CAI41481.1| 805|Homo sapiens WD repeat domain 44 pro... 59 3e-08
AL391474-1|CAI41402.1| 913|Homo sapiens WD repeat domain 44 pro... 59 3e-08
AK127556-1|BAC87033.1| 429|Homo sapiens protein ( Homo sapiens ... 59 3e-08
AK092077-1|BAC03799.1| 616|Homo sapiens protein ( Homo sapiens ... 59 3e-08
BC015887-1|AAH15887.1| 404|Homo sapiens WD repeat and SOCS box-... 58 5e-08
AF229181-1|AAF71302.1| 404|Homo sapiens CS box-containing WD pr... 58 5e-08
AF163324-1|AAF80478.1| 404|Homo sapiens WSB-2 protein. 58 5e-08
AF103939-1|AAD19904.1| 649|Homo sapiens echinoderm microtubule-... 58 5e-08
AB209773-1|BAD93010.1| 574|Homo sapiens echinoderm microtubule ... 58 5e-08
EF011617-1|ABK41107.1| 423|Homo sapiens CDW7/WDR12 protein. 58 7e-08
BC008082-1|AAH08082.1| 423|Homo sapiens WD repeat domain 12 pro... 58 7e-08
AK001743-1|BAA91875.1| 423|Homo sapiens protein ( Homo sapiens ... 58 7e-08
AC010900-2|AAY24287.1| 423|Homo sapiens unknown protein. 58 7e-08
AB007918-1|BAA32294.2| 1628|Homo sapiens KIAA0449 protein protein. 58 7e-08
BC130473-1|AAI30474.1| 522|Homo sapiens transducin (beta)-like ... 58 9e-08
BC130471-1|AAI30472.1| 522|Homo sapiens transducin (beta)-like ... 58 9e-08
AL121993-4|CAI22739.1| 943|Homo sapiens WD repeat domain 3 prot... 58 9e-08
AK022782-1|BAB14243.1| 423|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AK022781-1|BAB14242.1| 423|Homo sapiens protein ( Homo sapiens ... 58 9e-08
AF332222-1|AAK13474.1| 522|Homo sapiens transducin beta-like 1 ... 58 9e-08
AF332221-1|AAK13473.1| 522|Homo sapiens transducin beta-like 1 ... 58 9e-08
AF332220-1|AAK13472.1| 522|Homo sapiens transducin beta-like 1 ... 58 9e-08
AF083217-1|AAD45865.1| 943|Homo sapiens WD repeat protein WDR3 ... 58 9e-08
AB209201-1|BAD92438.1| 466|Homo sapiens WD repeat-containing pr... 58 9e-08
AY358182-1|AAQ88549.1| 470|Homo sapiens SSGL9393 protein. 57 1e-07
AK027854-1|BAB55412.1| 504|Homo sapiens protein ( Homo sapiens ... 57 1e-07
AF242546-1|AAF60355.1| 423|Homo sapiens YTM1 protein. 57 1e-07
AB209899-1|BAD93136.1| 967|Homo sapiens Hypothetical protein DK... 57 1e-07
U02609-1|AAA18945.1| 519|Homo sapiens transducin-like protein p... 57 2e-07
BC006449-1|AAH06449.1| 489|Homo sapiens coronin, actin binding ... 57 2e-07
AL607085-2|CAI15166.1| 494|Homo sapiens novel protein protein. 57 2e-07
AF177377-1|AAG09279.2| 981|Homo sapiens cytoplasmic protein pro... 57 2e-07
AC006038-1|AAY15086.1| 911|Homo sapiens unknown protein. 57 2e-07
AB209579-1|BAD92816.1| 287|Homo sapiens coronin, actin binding ... 57 2e-07
AB023199-1|BAA76826.2| 502|Homo sapiens KIAA0982 protein protein. 57 2e-07
BC117306-1|AAI17307.1| 698|Homo sapiens WD repeat domain 65 pro... 56 2e-07
BC117280-1|AAI17281.1| 698|Homo sapiens WD repeat domain 65 pro... 56 2e-07
BC002489-1|AAH02489.1| 606|Homo sapiens WD repeat domain 1 prot... 56 2e-07
AL139138-2|CAI18963.1| 698|Homo sapiens WD repeat domain 65 pro... 56 2e-07
AK093017-1|BAC04021.1| 619|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AK056562-1|BAB71217.1| 698|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AF020260-1|AAD05045.1| 534|Homo sapiens WDR1 protein protein. 56 2e-07
AF020056-1|AAD05044.1| 606|Homo sapiens WDR1 protein protein. 56 2e-07
AB010427-1|BAA31855.2| 606|Homo sapiens NORI-1 protein. 56 2e-07
BX538346-1|CAD98141.1| 147|Homo sapiens hypothetical protein pr... 56 3e-07
BC000201-1|AAH00201.1| 606|Homo sapiens WD repeat domain 1 prot... 56 3e-07
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2... 56 3e-07
AM177180-1|CAJ45484.1| 1670|Homo sapiens kinesin-like protein KI... 56 3e-07
AK222897-1|BAD96617.1| 606|Homo sapiens WD repeat-containing pr... 56 3e-07
AK222764-1|BAD96484.1| 606|Homo sapiens WD repeat-containing pr... 56 3e-07
AF450487-1|AAP97680.1| 1662|Homo sapiens kinesin-like protein KI... 56 3e-07
AB209746-1|BAD92983.1| 624|Homo sapiens WD repeat-containing pr... 56 3e-07
AB051495-1|BAB21799.2| 1657|Homo sapiens KIAA1708 protein. 56 3e-07
U20980-1|AAA76737.1| 559|Homo sapiens chromatin assembly factor... 56 4e-07
BX537855-1|CAD97863.1| 974|Homo sapiens hypothetical protein pr... 56 4e-07
BC021218-1|AAH21218.1| 559|Homo sapiens chromatin assembly fact... 56 4e-07
AP001725-3|BAA95549.1| 559|Homo sapiens chromatin assembly fact... 56 4e-07
AP000694-1|BAA89426.1| 559|Homo sapiens chromatin assembly fact... 56 4e-07
AF240696-1|AAF82746.1| 275|Homo sapiens WSB1 isoform 2 protein. 56 4e-07
U88871-1|AAC51238.1| 323|Homo sapiens HsPex7p protein. 55 5e-07
U76560-1|AAB50556.1| 323|Homo sapiens peroxisome targeting sign... 55 5e-07
CR542076-1|CAG46873.1| 323|Homo sapiens PEX7 protein. 55 5e-07
CR542054-1|CAG46851.1| 323|Homo sapiens PEX7 protein. 55 5e-07
BT007115-1|AAP35779.1| 493|Homo sapiens Fzr1 protein protein. 55 5e-07
BC013413-1|AAH13413.1| 493|Homo sapiens fizzy/cell division cyc... 55 5e-07
BC008809-1|AAH08809.2| 302|Homo sapiens AAMP protein protein. 55 5e-07
BC006268-1|AAH06268.1| 323|Homo sapiens peroxisomal biogenesis ... 55 5e-07
AL365223-4|CAI15714.1| 323|Homo sapiens peroxisomal biogenesis ... 55 5e-07
AL121933-2|CAI15471.1| 323|Homo sapiens peroxisomal biogenesis ... 55 5e-07
AF433157-1|AAL28117.1| 404|Homo sapiens CDC20-like 1b protein. 55 5e-07
AF180814-1|AAF37350.1| 323|Homo sapiens peroxisomal PTS2 recept... 55 5e-07
AF083810-1|AAD52030.1| 493|Homo sapiens fizzy-related protein p... 55 5e-07
AC005787-1|AAC62835.1| 493|Homo sapiens R33374_1 protein. 55 5e-07
AB033068-1|BAA86556.1| 504|Homo sapiens KIAA1242 protein protein. 55 5e-07
M99438-1|AAA61194.1| 772|Homo sapiens transducin-like enhancer ... 55 7e-07
BC017364-1|AAH17364.1| 743|Homo sapiens transducin-like enhance... 55 7e-07
AM177179-1|CAJ45483.1| 1621|Homo sapiens kinesin-like protein KI... 55 7e-07
AK223073-1|BAD96793.1| 474|Homo sapiens coronin, actin binding ... 55 7e-07
AC007766-2|AAD38075.1| 553|Homo sapiens TLE2_HUMAN [AA 191- 743... 55 7e-07
AB013463-1|BAA86955.1| 404|Homo sapiens Fzr2 protein. 55 7e-07
AB013462-1|BAA86954.1| 496|Homo sapiens Fzr1 protein. 55 7e-07
U18300-1|AAB07897.1| 427|Homo sapiens DDBb p48 protein. 54 9e-07
EF011614-1|ABK41104.1| 446|Homo sapiens CDW4/GRWD1 protein. 54 9e-07
BT007139-1|AAP35803.1| 427|Homo sapiens damage-specific DNA bin... 54 9e-07
BC047572-1|AAH47572.1| 433|Homo sapiens KIF21A protein protein. 54 9e-07
BC012938-1|AAH12938.1| 446|Homo sapiens TBL2 protein protein. 54 9e-07
BC002440-1|AAH02440.1| 446|Homo sapiens glutamate-rich WD repea... 54 9e-07
BC002342-1|AAH02342.1| 474|Homo sapiens coronin, actin binding ... 54 9e-07
BC000093-1|AAH00093.1| 427|Homo sapiens damage-specific DNA bin... 54 9e-07
AY358518-1|AAQ88882.1| 447|Homo sapiens TBL2 protein. 54 9e-07
AY220533-1|AAO25655.1| 427|Homo sapiens damage-specific DNA bin... 54 9e-07
AL162070-1|CAB82406.1| 495|Homo sapiens hypothetical protein pr... 54 9e-07
AK074619-1|BAC11093.1| 447|Homo sapiens protein ( Homo sapiens ... 54 9e-07
AF337808-1|AAK17998.1| 446|Homo sapiens glutamate rich WD repea... 54 9e-07
AF097485-1|AAF06824.1| 447|Homo sapiens transducin beta-like 2 ... 54 9e-07
AF097484-1|AAF06823.1| 447|Homo sapiens transducin beta-like 2 ... 54 9e-07
AF056183-1|AAD28083.1| 426|Homo sapiens WS beta-transducin repe... 54 9e-07
AB209909-1|BAD93146.1| 501|Homo sapiens coronin, actin binding ... 54 9e-07
AB075822-1|BAB85528.1| 445|Homo sapiens KIAA1942 protein protein. 54 9e-07
AB030656-1|BAA83077.1| 474|Homo sapiens hCRNN4 protein. 54 9e-07
X72841-1|CAA51360.1| 425|Homo sapiens IEF 7442 protein. 54 1e-06
U35143-1|AAC50231.1| 425|Homo sapiens retinoblastoma-binding pr... 54 1e-06
CR541701-1|CAG46502.1| 425|Homo sapiens RBBP7 protein. 54 1e-06
BC114501-1|AAI14502.1| 425|Homo sapiens retinoblastoma binding ... 54 1e-06
BC114500-1|AAI14501.1| 425|Homo sapiens retinoblastoma binding ... 54 1e-06
BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein. 54 1e-06
AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase specif... 54 1e-06
AL929302-6|CAI41284.1| 420|Homo sapiens retinoblastoma binding ... 54 1e-06
AL929302-5|CAI41283.1| 469|Homo sapiens retinoblastoma binding ... 54 1e-06
AL117629-1|CAB56021.1| 192|Homo sapiens hypothetical protein pr... 54 1e-06
AK090597-1|BAC03485.1| 513|Homo sapiens protein ( Homo sapiens ... 54 1e-06
AK074676-1|BAC11130.1| 446|Homo sapiens protein ( Homo sapiens ... 54 1e-06
AJ005257-1|CAA06444.1| 86|Homo sapiens protein ( Homo sapiens ... 54 1e-06
BC036713-1|AAH36713.1| 542|Homo sapiens ATG16L2 protein protein. 54 2e-06
X74262-1|CAA52321.1| 425|Homo sapiens retinoblastoma binding pr... 53 2e-06
X71810-1|CAA50685.1| 410|Homo sapiens IEF SSP 9306 protein. 53 2e-06
>BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 660 bits (1630), Expect = 0.0
Identities = 310/504 (61%), Positives = 388/504 (76%), Gaps = 8/504 (1%)
Query: 1 MSLYCAISNXXXXXXXXSPTSGAVFERRIIEKYIIENGVDPINGKELRVEDLXXXXXXXX 60
MSL C+ISN SP S V+ERR+IEKYI ENG DPIN + L E L
Sbjct: 1 MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHP 60
Query: 61 XXXXXXSATSIPATLKSMQDEWDALMLHAFTQRQQLQTARQELSHALYQHDAACRVIARL 120
SATSIPA LK++QDEWDA+MLH+FT RQQLQT RQELSHALYQHDAACRVIARL
Sbjct: 61 IRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARL 120
Query: 121 TKEVTAAREALATLKPQAGIAAPQAPHPTEXXXXXXXX-------XXXXXDVVSRLQERA 173
TKEVTAAREALATLKPQAG+ PQA ++ +++ +LQ++A
Sbjct: 121 TKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKA 180
Query: 174 TALTQERKRRGRTLPEGLLAPEQIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTG 233
T LT ERK+RG+T+PE L+ PE++ + +ASH GLHSAS+PGIL+LD+ PSD +K+LTG
Sbjct: 181 TVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTG 240
Query: 234 GNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTA 293
G D+N VF+K +EQ++A LKGHTKKVT V++HP +D V +ASPD TIR+W+VP +
Sbjct: 241 GADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQ 300
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD-FSGVSLTTAQFHP 352
++R+H+ VTGLSLH TGDY+LS+S DQ+WAFSDI+TG++LTKV+D SG SLT AQFHP
Sbjct: 301 VVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHP 360
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
DGLIFGTGT +SQ+KIWDLKE++NVANFPGH GP+TSI+FSENGYYLATAA+DS VKLWD
Sbjct: 361 DGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
Query: 413 LRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATG 472
LRKLKNFKT+QL+ N+ +K L FDQSGTYLA+ GTDV++Y+C+QW E+ F +H+ TG
Sbjct: 421 LRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTG 480
Query: 473 VRFGKNAQYLASTSMDRTLKLYGI 496
V FG +A+++AST MDR+LK Y +
Sbjct: 481 VAFGHHAKFIASTGMDRSLKFYSL 504
>BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 660 bits (1630), Expect = 0.0
Identities = 310/504 (61%), Positives = 388/504 (76%), Gaps = 8/504 (1%)
Query: 1 MSLYCAISNXXXXXXXXSPTSGAVFERRIIEKYIIENGVDPINGKELRVEDLXXXXXXXX 60
MSL C+ISN SP S V+ERR+IEKYI ENG DPIN + L E L
Sbjct: 1 MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHP 60
Query: 61 XXXXXXSATSIPATLKSMQDEWDALMLHAFTQRQQLQTARQELSHALYQHDAACRVIARL 120
SATSIPA LK++QDEWDA+MLH+FT RQQLQT RQELSHALYQHDAACRVIARL
Sbjct: 61 IRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARL 120
Query: 121 TKEVTAAREALATLKPQAGIAAPQAPHPTEXXXXXXXX-------XXXXXDVVSRLQERA 173
TKEVTAAREALATLKPQAG+ PQA ++ +++ +LQ++A
Sbjct: 121 TKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKA 180
Query: 174 TALTQERKRRGRTLPEGLLAPEQIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTG 233
T LT ERK+RG+T+PE L+ PE++ + +ASH GLHSAS+PGIL+LD+ PSD +K+LTG
Sbjct: 181 TVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTG 240
Query: 234 GNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTA 293
G D+N VF+K +EQ++A LKGHTKKVT V++HP +D V +ASPD TIR+W+VP +
Sbjct: 241 GADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQ 300
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD-FSGVSLTTAQFHP 352
++R+H+ VTGLSLH TGDY+LS+S DQ+WAFSDI+TG++LTKV+D SG SLT AQFHP
Sbjct: 301 VVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHP 360
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
DGLIFGTGT +SQ+KIWDLKE++NVANFPGH GP+TSI+FSENGYYLATAA+DS VKLWD
Sbjct: 361 DGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
Query: 413 LRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATG 472
LRKLKNFKT+QL+ N+ +K L FDQSGTYLA+ GTDV++Y+C+QW E+ F +H+ TG
Sbjct: 421 LRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTG 480
Query: 473 VRFGKNAQYLASTSMDRTLKLYGI 496
V FG +A+++AST MDR+LK Y +
Sbjct: 481 VAFGHHAKFIASTGMDRSLKFYSL 504
>BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 660 bits (1630), Expect = 0.0
Identities = 310/504 (61%), Positives = 388/504 (76%), Gaps = 8/504 (1%)
Query: 1 MSLYCAISNXXXXXXXXSPTSGAVFERRIIEKYIIENGVDPINGKELRVEDLXXXXXXXX 60
MSL C+ISN SP S V+ERR+IEKYI ENG DPIN + L E L
Sbjct: 1 MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHP 60
Query: 61 XXXXXXSATSIPATLKSMQDEWDALMLHAFTQRQQLQTARQELSHALYQHDAACRVIARL 120
SATSIPA LK++QDEWDA+MLH+FT RQQLQT RQELSHALYQHDAACRVIARL
Sbjct: 61 IRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARL 120
Query: 121 TKEVTAAREALATLKPQAGIAAPQAPHPTEXXXXXXXX-------XXXXXDVVSRLQERA 173
TKEVTAAREALATLKPQAG+ PQA ++ +++ +LQ++A
Sbjct: 121 TKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKA 180
Query: 174 TALTQERKRRGRTLPEGLLAPEQIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTG 233
T LT ERK+RG+T+PE L+ PE++ + +ASH GLHSAS+PGIL+LD+ PSD +K+LTG
Sbjct: 181 TVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTG 240
Query: 234 GNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTA 293
G D+N VF+K +EQ++A LKGHTKKVT V++HP +D V +ASPD TIR+W+VP +
Sbjct: 241 GADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQ 300
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD-FSGVSLTTAQFHP 352
++R+H+ VTGLSLH TGDY+LS+S DQ+WAFSDI+TG++LTKV+D SG SLT AQFHP
Sbjct: 301 VVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHP 360
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
DGLIFGTGT +SQ+KIWDLKE++NVANFPGH GP+TSI+FSENGYYLATAA+DS VKLWD
Sbjct: 361 DGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
Query: 413 LRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATG 472
LRKLKNFKT+QL+ N+ +K L FDQSGTYLA+ GTDV++Y+C+QW E+ F +H+ TG
Sbjct: 421 LRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTG 480
Query: 473 VRFGKNAQYLASTSMDRTLKLYGI 496
V FG +A+++AST MDR+LK Y +
Sbjct: 481 VAFGHHAKFIASTGMDRSLKFYSL 504
>AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein
NMP200 protein.
Length = 504
Score = 660 bits (1630), Expect = 0.0
Identities = 310/504 (61%), Positives = 388/504 (76%), Gaps = 8/504 (1%)
Query: 1 MSLYCAISNXXXXXXXXSPTSGAVFERRIIEKYIIENGVDPINGKELRVEDLXXXXXXXX 60
MSL C+ISN SP S V+ERR+IEKYI ENG DPIN + L E L
Sbjct: 1 MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHP 60
Query: 61 XXXXXXSATSIPATLKSMQDEWDALMLHAFTQRQQLQTARQELSHALYQHDAACRVIARL 120
SATSIPA LK++QDEWDA+MLH+FT RQQLQT RQELSHALYQHDAACRVIARL
Sbjct: 61 IRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARL 120
Query: 121 TKEVTAAREALATLKPQAGIAAPQAPHPTEXXXXXXXX-------XXXXXDVVSRLQERA 173
TKEVTAAREALATLKPQAG+ PQA ++ +++ +LQ++A
Sbjct: 121 TKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKA 180
Query: 174 TALTQERKRRGRTLPEGLLAPEQIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTG 233
T LT ERK+RG+T+PE L+ PE++ + +ASH GLHSAS+PGIL+LD+ PSD +K+LTG
Sbjct: 181 TVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTG 240
Query: 234 GNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTA 293
G D+N VF+K +EQ++A LKGHTKKVT V++HP +D V +ASPD TIR+W+VP +
Sbjct: 241 GADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQ 300
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD-FSGVSLTTAQFHP 352
++R+H+ VTGLSLH TGDY+LS+S DQ+WAFSDI+TG++LTKV+D SG SLT AQFHP
Sbjct: 301 VVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHP 360
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
DGLIFGTGT +SQ+KIWDLKE++NVANFPGH GP+TSI+FSENGYYLATAA+DS VKLWD
Sbjct: 361 DGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWD 420
Query: 413 LRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATG 472
LRKLKNFKT+QL+ N+ +K L FDQSGTYLA+ GTDV++Y+C+QW E+ F +H+ TG
Sbjct: 421 LRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTG 480
Query: 473 VRFGKNAQYLASTSMDRTLKLYGI 496
V FG +A+++AST MDR+LK Y +
Sbjct: 481 VAFGHHAKFIASTGMDRSLKFYSL 504
>CR456762-1|CAG33043.1| 655|Homo sapiens KATNB1 protein.
Length = 655
Score = 122 bits (294), Expect = 3e-27
Identities = 69/242 (28%), Positives = 114/242 (47%), Gaps = 3/242 (1%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDT 271
A + SL + + L TGG+D +++ + + L GHT V V + E+
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
Query: 272 VITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTG 331
++ S +IRVW++ ++ L H + L HP G++V S S D + DIR
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 332 QLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSIS 391
+ + S ++ +F PDG + ++ VK+WDL ++ FPGH GPV +
Sbjct: 138 GCVFRYRGHSQ-AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196
Query: 392 FSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-VR 450
F N Y LA+ + D ++ WDL K + I+ E ++ + F+ G L D +R
Sbjct: 197 FHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPG-PVRSVLFNPDGCCLYSGCQDSLR 255
Query: 451 VY 452
VY
Sbjct: 256 VY 257
Score = 76.2 bits (179), Expect = 3e-13
Identities = 57/208 (27%), Positives = 96/208 (46%), Gaps = 13/208 (6%)
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQH----WAFSDIRTGQLLT-KVSDFSGVSLTTAQFH 351
+H V+ L L +L+T D W+ + LT S V L T
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT---- 73
Query: 352 PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
P+ LI G+++ +++WDL+ + GH + S+ F G ++A+ ++D+ +KLW
Sbjct: 74 PEELIVA-GSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
Query: 412 DLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTAS 469
D+R+ K + A++ L F G +LA A D V+++ + + F HT
Sbjct: 133 DIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 470 ATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V F N LAS S DRT++ + +E
Sbjct: 192 VNVVEFHPNEYLLASGSSDRTIRFWDLE 219
>BT007022-1|AAP35668.1| 655|Homo sapiens katanin p80
(WD40-containing) subunit B 1 protein.
Length = 655
Score = 122 bits (294), Expect = 3e-27
Identities = 69/242 (28%), Positives = 114/242 (47%), Gaps = 3/242 (1%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDT 271
A + SL + + L TGG+D +++ + + L GHT V V + E+
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
Query: 272 VITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTG 331
++ S +IRVW++ ++ L H + L HP G++V S S D + DIR
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 332 QLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSIS 391
+ + S ++ +F PDG + ++ VK+WDL ++ FPGH GPV +
Sbjct: 138 GCVFRYRGHSQ-AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196
Query: 392 FSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-VR 450
F N Y LA+ + D ++ WDL K + I+ E ++ + F+ G L D +R
Sbjct: 197 FHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPG-PVRSVLFNPDGCCLYSGCQDSLR 255
Query: 451 VY 452
VY
Sbjct: 256 VY 257
Score = 76.2 bits (179), Expect = 3e-13
Identities = 57/208 (27%), Positives = 96/208 (46%), Gaps = 13/208 (6%)
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQH----WAFSDIRTGQLLT-KVSDFSGVSLTTAQFH 351
+H V+ L L +L+T D W+ + LT S V L T
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT---- 73
Query: 352 PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
P+ LI G+++ +++WDL+ + GH + S+ F G ++A+ ++D+ +KLW
Sbjct: 74 PEELIVA-GSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
Query: 412 DLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTAS 469
D+R+ K + A++ L F G +LA A D V+++ + + F HT
Sbjct: 133 DIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 470 ATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V F N LAS S DRT++ + +E
Sbjct: 192 VNVVEFHPNEYLLASGSSDRTIRFWDLE 219
>BC001353-1|AAH01353.1| 655|Homo sapiens katanin p80 (WD repeat
containing) subunit B 1 protein.
Length = 655
Score = 122 bits (294), Expect = 3e-27
Identities = 69/242 (28%), Positives = 114/242 (47%), Gaps = 3/242 (1%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDT 271
A + SL + + L TGG+D +++ + + L GHT V V + E+
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
Query: 272 VITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTG 331
++ S +IRVW++ ++ L H + L HP G++V S S D + DIR
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 332 QLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSIS 391
+ + S ++ +F PDG + ++ VK+WDL ++ FPGH GPV +
Sbjct: 138 GCVFRYRGHSQ-AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196
Query: 392 FSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-VR 450
F N Y LA+ + D ++ WDL K + I+ E ++ + F+ G L D +R
Sbjct: 197 FHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPG-PVRSVLFNPDGCCLYSGCQDSLR 255
Query: 451 VY 452
VY
Sbjct: 256 VY 257
Score = 76.2 bits (179), Expect = 3e-13
Identities = 57/208 (27%), Positives = 96/208 (46%), Gaps = 13/208 (6%)
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQH----WAFSDIRTGQLLT-KVSDFSGVSLTTAQFH 351
+H V+ L L +L+T D W+ + LT S V L T
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT---- 73
Query: 352 PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
P+ LI G+++ +++WDL+ + GH + S+ F G ++A+ ++D+ +KLW
Sbjct: 74 PEELIVA-GSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLW 132
Query: 412 DLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTAS 469
D+R+ K + A++ L F G +LA A D V+++ + + F HT
Sbjct: 133 DIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 470 ATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V F N LAS S DRT++ + +E
Sbjct: 192 VNVVEFHPNEYLLASGSSDRTIRFWDLE 219
>BC007424-1|AAH07424.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 118 bits (284), Expect = 5e-26
Identities = 69/255 (27%), Positives = 120/255 (47%), Gaps = 11/255 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 268 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 327
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 328 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 386
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 387 FGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 446
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 447 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 506
Query: 483 ASTSMDRTLKLYGIE 497
A+ S DRT KL+ E
Sbjct: 507 ATCSYDRTFKLWMAE 521
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 285 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 343
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 344 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 403
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 404 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 462
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 463 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 512
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 407
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 408 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFL 464
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 465 LTGAYDNTAKIW 476
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 205 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 264
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 265 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 323 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 352
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 451 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 510
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 511 YDRTFKLW 518
>BC001588-1|AAH01588.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 118 bits (284), Expect = 5e-26
Identities = 69/255 (27%), Positives = 120/255 (47%), Gaps = 11/255 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 269 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 328
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 329 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 387
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 388 FGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 447
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 448 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 507
Query: 483 ASTSMDRTLKLYGIE 497
A+ S DRT KL+ E
Sbjct: 508 ATCSYDRTFKLWMAE 522
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 286 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 344
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 345 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 404
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 405 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 463
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 464 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 513
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 349 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 408
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 409 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFL 465
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 466 LTGAYDNTAKIW 477
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 206 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 265
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 266 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 323
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 324 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 353
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 452 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 511
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 512 YDRTFKLW 519
>AY572489-1|AAS78572.1| 521|Homo sapiens 60 kDa U4/U6
snRNP-specific spliceosomal protein protein.
Length = 521
Score = 118 bits (284), Expect = 5e-26
Identities = 69/255 (27%), Positives = 120/255 (47%), Gaps = 11/255 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 268 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 327
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 328 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 386
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 387 FGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 446
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 447 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 506
Query: 483 ASTSMDRTLKLYGIE 497
A+ S DRT KL+ E
Sbjct: 507 ATCSYDRTFKLWMAE 521
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 285 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 343
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 344 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 403
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 404 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 462
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 463 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 512
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 407
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 408 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFL 464
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 465 LTGAYDNTAKIW 476
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 205 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 264
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 265 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 323 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 352
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 451 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 510
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 511 YDRTFKLW 518
>AL449305-8|CAI10969.1| 521|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 521
Score = 118 bits (284), Expect = 5e-26
Identities = 69/255 (27%), Positives = 120/255 (47%), Gaps = 11/255 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 268 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 327
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 328 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 386
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 387 FGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 446
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 447 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 506
Query: 483 ASTSMDRTLKLYGIE 497
A+ S DRT KL+ E
Sbjct: 507 ATCSYDRTFKLWMAE 521
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 285 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 343
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 344 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 403
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 404 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 462
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 463 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 512
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 407
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 408 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFL 464
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 465 LTGAYDNTAKIW 476
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 205 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 264
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 265 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 323 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 352
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 451 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 510
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 511 YDRTFKLW 518
>AL449305-7|CAI10968.1| 522|Homo sapiens PRP4 pre-mRNA processing
factor 4 homolog (yeast) protein.
Length = 522
Score = 118 bits (284), Expect = 5e-26
Identities = 69/255 (27%), Positives = 120/255 (47%), Gaps = 11/255 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 269 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 328
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 329 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 387
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 388 FGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 447
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 448 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 507
Query: 483 ASTSMDRTLKLYGIE 497
A+ S DRT KL+ E
Sbjct: 508 ATCSYDRTFKLWMAE 522
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 286 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 344
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 345 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 404
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 405 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 463
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 464 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 513
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 349 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 408
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 409 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFL 465
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 466 LTGAYDNTAKIW 477
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 206 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 265
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 266 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 323
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 324 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 353
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 452 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 511
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 512 YDRTFKLW 519
>AF052432-1|AAC09328.1| 655|Homo sapiens katanin p80 subunit
protein.
Length = 655
Score = 118 bits (284), Expect = 5e-26
Identities = 68/242 (28%), Positives = 113/242 (46%), Gaps = 3/242 (1%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDT 271
A + SL + + L TGG+D +++ + + L GHT V V + E+
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEEL 77
Query: 272 VITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTG 331
++ S +IRVW++ ++ L + L HP G++V S S D + DIR
Sbjct: 78 IVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWDIRRK 137
Query: 332 QLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSIS 391
+ + S ++ +F PDG + ++ VK+WDL ++ FPGH GPV +
Sbjct: 138 GCVFRYRGHSQ-AVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVE 196
Query: 392 FSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-VR 450
F N Y LA+ + D ++ WDL K + I+ E ++ + F+ G L D +R
Sbjct: 197 FHPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGEPG-PVRSVLFNPDGCCLYSGCQDSLR 255
Query: 451 VY 452
VY
Sbjct: 256 VY 257
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/208 (26%), Positives = 94/208 (45%), Gaps = 13/208 (6%)
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQH----WAFSDIRTGQLLT-KVSDFSGVSLTTAQFH 351
+H V+ L L +L+T D W+ + LT S V L T
Sbjct: 18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNT---- 73
Query: 352 PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
P+ LI G+++ +++WDL+ + G + S+ F G ++A+ ++D+ +KLW
Sbjct: 74 PEELIVA-GSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLW 132
Query: 412 DLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTAS 469
D+R+ K + A++ L F G +LA A D V+++ + + F HT
Sbjct: 133 DIRR-KGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGP 191
Query: 470 ATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V F N LAS S D T++ + +E
Sbjct: 192 VNVVEFHPNEYLLASGSSDGTIRFWDLE 219
>AF016369-1|AAC51925.1| 522|Homo sapiens U4/U6 small nuclear
ribonucleoprotein hPrp4 protein.
Length = 522
Score = 118 bits (284), Expect = 5e-26
Identities = 69/255 (27%), Positives = 120/255 (47%), Gaps = 11/255 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 269 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 328
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 329 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 387
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 388 FGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 447
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 448 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 507
Query: 483 ASTSMDRTLKLYGIE 497
A+ S DRT KL+ E
Sbjct: 508 ATCSYDRTFKLWMAE 522
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 286 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 344
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 345 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 404
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 405 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 463
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 464 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 513
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 229 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 288
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 289 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 348
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 349 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 408
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 409 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFL 465
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 466 LTGAYDNTAKIW 477
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 206 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 265
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 266 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 323
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 324 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 353
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 452 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 511
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 512 YDRTFKLW 519
>AB209797-1|BAD93034.1| 537|Homo sapiens PRPF4 protein variant
protein.
Length = 537
Score = 118 bits (284), Expect = 5e-26
Identities = 69/255 (27%), Positives = 120/255 (47%), Gaps = 11/255 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 284 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 343
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 344 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 402
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 403 FGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 462
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 463 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 522
Query: 483 ASTSMDRTLKLYGIE 497
A+ S DRT KL+ E
Sbjct: 523 ATCSYDRTFKLWMAE 537
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 301 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 359
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 360 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 419
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 420 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 478
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 479 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 528
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 244 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 303
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 304 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 363
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 364 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 423
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 424 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFL 480
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 481 LTGAYDNTAKIW 492
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 221 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 280
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 281 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 338
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 339 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 368
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 467 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 526
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 527 YDRTFKLW 534
>CR457105-1|CAG33386.1| 521|Homo sapiens PRPF4 protein.
Length = 521
Score = 118 bits (283), Expect = 6e-26
Identities = 68/252 (26%), Positives = 119/252 (47%), Gaps = 11/252 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 268 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 327
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 328 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 386
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 387 FGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 446
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 447 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 506
Query: 483 ASTSMDRTLKLY 494
A+ S DRT KL+
Sbjct: 507 ATCSYDRTFKLW 518
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 285 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 343
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 344 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 403
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 404 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 462
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 463 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 512
Score = 73.7 bits (173), Expect = 1e-12
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLK 407
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 408 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFL 464
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 465 LTGAYDNTAKIW 476
Score = 62.9 bits (146), Expect = 3e-09
Identities = 37/153 (24%), Positives = 64/153 (41%), Gaps = 3/153 (1%)
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
+T P + + + VK+W L VA+ GH V + + +G +L T D
Sbjct: 284 STVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 343
Query: 406 SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVF 463
+LWDL + Q + + ++ F Q G+ G D RV+ R + +
Sbjct: 344 RSWRLWDLEAQEEILH-QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL 402
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
H G+ F N ++A+ S D T K++ +
Sbjct: 403 EGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL 435
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 205 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 264
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 265 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 323 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 352
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 451 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 510
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 511 YDRTFKLW 518
>AF001687-1|AAB87640.1| 521|Homo sapiens U4/U6 snRNP 60 kDa protein
protein.
Length = 521
Score = 115 bits (277), Expect = 3e-25
Identities = 68/255 (26%), Positives = 120/255 (47%), Gaps = 11/255 (4%)
Query: 253 LKGHTKKVTRVIYHP------DEDTVITAS--PDHTIRVWNVPTSQTTAILRSHDGPVTG 304
L+GH V +++HP D V AS D ++++W++ + + A + H V
Sbjct: 268 LRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVAR 327
Query: 305 LSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
+ HP+G ++ +T D+ W D+ + + S + + FH DG + GTG ++
Sbjct: 328 VMWHPSGRFLGTTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDA 386
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++WDL+ + H+ + I+FS NGY++AT + D+ K+WDLR+ + TI
Sbjct: 387 FGRVWDLRTGRCIMFLEDHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPP 446
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYL 482
+N G +L D +++ W LK H G+ + Q +
Sbjct: 447 HQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLI 506
Query: 483 ASTSMDRTLKLYGIE 497
A+ S DRT KL+ +E
Sbjct: 507 ATYSYDRTFKLWMLE 521
Score = 90.6 bits (215), Expect = 1e-17
Identities = 51/194 (26%), Positives = 96/194 (49%), Gaps = 3/194 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 285 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 343
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 344 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 403
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
D + F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 404 DHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGN 462
Query: 398 YLATAAEDSCVKLW 411
+L T A D+ K+W
Sbjct: 463 FLLTGAYDNTAKIW 476
Score = 74.5 bits (175), Expect = 8e-13
Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 15/252 (5%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
G + ++ + P+ + TA ++W+VP LR H+ V + HP
Sbjct: 228 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVS 287
Query: 315 L---STSSDQHWAFSDIRTGQLLT--KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVK 367
L + A ++ L + V+D G V + +HP G GT + +
Sbjct: 288 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWR 347
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLE 425
+WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L+
Sbjct: 348 LWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEDHLK 407
Query: 426 ENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQYL 482
E Y I F +G ++A D +V+ RQ + + H TGV+F + +L
Sbjct: 408 EIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGNFL 464
Query: 483 ASTSMDRTLKLY 494
+ + D T K++
Sbjct: 465 LTGAYDNTAKIW 476
Score = 35.9 bits (79), Expect = 0.33
Identities = 34/150 (22%), Positives = 61/150 (40%), Gaps = 13/150 (8%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T T Q L+ +N + G P++ FS N LATA KLW +
Sbjct: 205 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 264
Query: 419 FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFN-----------DHT 467
T++ N + + F T +++ DV + C +K+++ HT
Sbjct: 265 LHTLR-GHNTNVGAIVFHPKST-VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 323 VRVARVMWHPSGRFLGTTCYDRSWRLWDLE 352
Score = 32.7 bits (71), Expect = 3.1
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 451 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATYS 510
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 511 YDRTFKLW 518
>U82756-1|AAC02261.1| 520|Homo sapiens WD splicing factor Hprp4p
protein.
Length = 520
Score = 113 bits (273), Expect = 1e-24
Identities = 62/244 (25%), Positives = 115/244 (47%), Gaps = 3/244 (1%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H+ + V P + + + + D ++++W++ + + A + H V + HP+G ++
Sbjct: 278 HSIPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLG 337
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
+T D+ W D+ + + S + + FH DG + GTG ++ ++WDL+
Sbjct: 338 TTCYDRSWRLWDLEAQEEILHQEGHS-MGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGR 396
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCF 435
+ GH+ + I+FS NGY++AT + D+ K+WDLR+ + TI +N
Sbjct: 397 CIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFE 456
Query: 436 DQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
G +L D +++ W LK H G+ + Q +A+ S DRT KL
Sbjct: 457 PIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKL 516
Query: 494 YGIE 497
+ E
Sbjct: 517 WMAE 520
Score = 89.4 bits (212), Expect = 3e-17
Identities = 57/231 (24%), Positives = 105/231 (45%), Gaps = 4/231 (1%)
Query: 219 SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
++ ++P D + L + D + +++ D+++ VA ++GHT +V RV++HP + T D
Sbjct: 284 TVSLDPKDVN-LASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYD 342
Query: 279 HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS 338
+ R+W++ + H V ++ H G + D D+RTG+ + +
Sbjct: 343 RSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLE 402
Query: 339 DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE-NGY 397
+ F P+G TG+ ++ K+WDL+++ V P H VT + F +G
Sbjct: 403 GHL-KEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGN 461
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+L T A D+ K+W KT+ E + L G +A D
Sbjct: 462 FLLTGAYDNTAKIWTHPGWSPLKTLAGHEG-KVMGLDISSDGQLIATCSYD 511
Score = 71.3 bits (167), Expect = 7e-12
Identities = 59/253 (23%), Positives = 110/253 (43%), Gaps = 17/253 (6%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDG--------PVTGLS 306
G + ++ + P+ + TA ++W+VP LR H+ P + +S
Sbjct: 227 GDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTKKEQLHSIPKSTVS 286
Query: 307 LHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQV 366
L P + S ++D + + + + + + V + +HP G GT +
Sbjct: 287 LDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT-VRVARVMWHPSGRFLGTTCYDRSW 345
Query: 367 KIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQL 424
++WDL+ Q + + GH V I+F ++G T D+ ++WDLR + F L
Sbjct: 346 RLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHL 405
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK-NAQY 481
+E Y I F +G ++A D +V+ RQ + + H TGV+F + +
Sbjct: 406 KEIYGIN---FSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNF 462
Query: 482 LASTSMDRTLKLY 494
L + + D T K++
Sbjct: 463 LLTGAYDNTAKIW 475
Score = 65.7 bits (153), Expect = 4e-10
Identities = 39/164 (23%), Positives = 67/164 (40%), Gaps = 3/164 (1%)
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
TK + +T P + + + VK+W L VA+ GH V + +
Sbjct: 272 TKKEQLHSIPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHP 331
Query: 395 NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDV--RVY 452
+G +L T D +LWDL + Q + + ++ F Q G+ G D RV+
Sbjct: 332 SGRFLGTTCYDRSWRLWDLEAQEEI-LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVW 390
Query: 453 LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
R + + H G+ F N ++A+ S D T K++ +
Sbjct: 391 DLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDL 434
Score = 37.1 bits (82), Expect = 0.14
Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 11/149 (7%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD------ 412
T T Q L+ +N + G P++ FS N LATA KLW
Sbjct: 204 TRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFSPNSKMLATACWSGLCKLWSVPDCNL 263
Query: 413 LRKLKNFKTIQLEENYAIKE--LCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTA 468
L L+ T + E+ ++I + + D LA D V+++ + + HT
Sbjct: 264 LHTLRGHNT-KKEQLHSIPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTV 322
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGIE 497
V + + ++L +T DR+ +L+ +E
Sbjct: 323 RVARVMWHPSGRFLGTTCYDRSWRLWDLE 351
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/68 (26%), Positives = 28/68 (41%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + P + LLTG D A ++ + L GH KV + D + T S
Sbjct: 450 VTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVMGLDISSDGQLIATCS 509
Query: 277 PDHTIRVW 284
D T ++W
Sbjct: 510 YDRTFKLW 517
>AL121990-7|CAI22015.1| 589|Homo sapiens TAF5-like RNA polymerase
II, p300/CBP-associated factor (PCAF)-associated facto
protein.
Length = 589
Score = 105 bits (252), Expect = 4e-22
Identities = 78/256 (30%), Positives = 120/256 (46%), Gaps = 12/256 (4%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPV 302
N TE + IL+GH V + D +++ S D +IR W++ + T + + H PV
Sbjct: 330 NAGTE--MKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPV 387
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
L + P Y S S D+ W+F RT L + V +FHP+ T
Sbjct: 388 WDLDISPYSLYFASGSHDRTARLWSFD--RTYPLRIYAGHLADVDCV--KFHPNSNYLAT 443
Query: 360 GTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNF 419
G+ + V++W ++ ++V F GH GPV S++FS NG YLA+A ED +KLWDL +
Sbjct: 444 GSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLY 503
Query: 420 KTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK 477
K ++ + I L F +A A D VRV+ R + ++ GV G+
Sbjct: 504 KELRGHTD-NITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQ 562
Query: 478 NAQYLASTSMDRTLKL 493
+ L+ M L L
Sbjct: 563 MSNVLSVQFMACNLLL 578
Score = 89.0 bits (211), Expect = 3e-17
Identities = 48/157 (30%), Positives = 80/157 (50%), Gaps = 4/157 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ LDI+P +G +DR A +++ D + I GH V V +HP+ + + T S
Sbjct: 387 VWDLDISPYS-LYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGS 445
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T+R+W+ + + H GPV L+ P G Y+ S DQ D+ +G L +
Sbjct: 446 TDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKE 505
Query: 337 VSDFSGVSLTTAQFHPD-GLIFGTGTENSQVKIWDLK 372
+ + ++T+ F PD GLI +NS V++WD++
Sbjct: 506 LRGHTD-NITSLTFSPDSGLIASASMDNS-VRVWDIR 540
Score = 80.2 bits (189), Expect = 2e-14
Identities = 47/190 (24%), Positives = 88/190 (46%), Gaps = 1/190 (0%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D S LL+ D + ++ + + +GH V + P + S D T R+W
Sbjct: 352 ADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLW 411
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+ + I H V + HP +Y+ + S+D+ + G + + G
Sbjct: 412 SFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPV 471
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
L+ A F P+G + E+ ++K+WDL + GH +TS++FS + +A+A+
Sbjct: 472 LSLA-FSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASM 530
Query: 405 DSCVKLWDLR 414
D+ V++WD+R
Sbjct: 531 DNSVRVWDIR 540
Score = 78.2 bits (184), Expect = 6e-14
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 4/205 (1%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPD 353
ILR H GPV +LS S D + D+ + T + + P
Sbjct: 337 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTN-TVLYQGHAYPVWDLDISPY 395
Query: 354 GLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
L F +G+ + ++W + + GH+ V + F N YLAT + D V+LW
Sbjct: 396 SLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSA 455
Query: 414 RKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYL--CRQWQELKVFNDHTASAT 471
++ + + + L F +G YLA AG D R+ L K HT + T
Sbjct: 456 QQGNSVRLFTGHRG-PVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT 514
Query: 472 GVRFGKNAQYLASTSMDRTLKLYGI 496
+ F ++ +AS SMD +++++ I
Sbjct: 515 SLTFSPDSGLIASASMDNSVRVWDI 539
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH GPV S F + L + +ED ++ WDL N Q Y + +L Y
Sbjct: 340 GHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQ-GHAYPVWDLDISPYSLY 398
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A D R++ + L+++ H A V+F N+ YLA+ S D+T++L+ +
Sbjct: 399 FASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQ 456
Score = 46.8 bits (106), Expect = 2e-04
Identities = 21/77 (27%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+LSL +P+ L + G D+ +++ + + L+GHT +T + + PD + +AS
Sbjct: 471 VLSLAFSPNG-KYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASAS 529
Query: 277 PDHTIRVWNVPTSQTTA 293
D+++RVW++ + +A
Sbjct: 530 MDNSVRVWDIRNTYCSA 546
Score = 31.5 bits (68), Expect = 7.1
Identities = 11/30 (36%), Positives = 18/30 (60%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQ 374
L TA+ PD + G +NS +K+W L+ +
Sbjct: 271 LNTAEISPDSKLLAAGFDNSCIKLWSLRSK 300
>AJ009770-1|CAA08816.1| 260|Homo sapiens putative transcription
factor protein.
Length = 260
Score = 105 bits (252), Expect = 4e-22
Identities = 78/256 (30%), Positives = 120/256 (46%), Gaps = 12/256 (4%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPV 302
N TE + IL+GH V + D +++ S D +IR W++ + T + + H PV
Sbjct: 1 NAGTE--MKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPV 58
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
L + P Y S S D+ W+F RT L + V +FHP+ T
Sbjct: 59 WDLDISPYSLYFASGSHDRTARLWSFD--RTYPLRIYAGHLADVDCV--KFHPNSNYLAT 114
Query: 360 GTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNF 419
G+ + V++W ++ ++V F GH GPV S++FS NG YLA+A ED +KLWDL +
Sbjct: 115 GSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLY 174
Query: 420 KTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK 477
K ++ + I L F +A A D VRV+ R + ++ GV G+
Sbjct: 175 KELRGHTD-NITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQ 233
Query: 478 NAQYLASTSMDRTLKL 493
+ L+ M L L
Sbjct: 234 MSNVLSVQFMACNLLL 249
Score = 89.0 bits (211), Expect = 3e-17
Identities = 48/157 (30%), Positives = 80/157 (50%), Gaps = 4/157 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ LDI+P +G +DR A +++ D + I GH V V +HP+ + + T S
Sbjct: 58 VWDLDISPYS-LYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGS 116
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T+R+W+ + + H GPV L+ P G Y+ S DQ D+ +G L +
Sbjct: 117 TDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKE 176
Query: 337 VSDFSGVSLTTAQFHPD-GLIFGTGTENSQVKIWDLK 372
+ + ++T+ F PD GLI +NS V++WD++
Sbjct: 177 LRGHTD-NITSLTFSPDSGLIASASMDNS-VRVWDIR 211
Score = 80.2 bits (189), Expect = 2e-14
Identities = 47/190 (24%), Positives = 88/190 (46%), Gaps = 1/190 (0%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D S LL+ D + ++ + + +GH V + P + S D T R+W
Sbjct: 23 ADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLW 82
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+ + I H V + HP +Y+ + S+D+ + G + + G
Sbjct: 83 SFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPV 142
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
L+ A F P+G + E+ ++K+WDL + GH +TS++FS + +A+A+
Sbjct: 143 LSLA-FSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASM 201
Query: 405 DSCVKLWDLR 414
D+ V++WD+R
Sbjct: 202 DNSVRVWDIR 211
Score = 78.2 bits (184), Expect = 6e-14
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 4/205 (1%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPD 353
ILR H GPV +LS S D + D+ + T + + P
Sbjct: 8 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTN-TVLYQGHAYPVWDLDISPY 66
Query: 354 GLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
L F +G+ + ++W + + GH+ V + F N YLAT + D V+LW
Sbjct: 67 SLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSA 126
Query: 414 RKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYL--CRQWQELKVFNDHTASAT 471
++ + + + L F +G YLA AG D R+ L K HT + T
Sbjct: 127 QQGNSVRLFTGHRG-PVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT 185
Query: 472 GVRFGKNAQYLASTSMDRTLKLYGI 496
+ F ++ +AS SMD +++++ I
Sbjct: 186 SLTFSPDSGLIASASMDNSVRVWDI 210
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH GPV S F + L + +ED ++ WDL N Q Y + +L Y
Sbjct: 11 GHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQ-GHAYPVWDLDISPYSLY 69
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A D R++ + L+++ H A V+F N+ YLA+ S D+T++L+ +
Sbjct: 70 FASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQ 127
Score = 46.8 bits (106), Expect = 2e-04
Identities = 21/77 (27%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+LSL +P+ L + G D+ +++ + + L+GHT +T + + PD + +AS
Sbjct: 142 VLSLAFSPNG-KYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASAS 200
Query: 277 PDHTIRVWNVPTSQTTA 293
D+++RVW++ + +A
Sbjct: 201 MDNSVRVWDIRNTYCSA 217
>AF069736-1|AAC39906.1| 589|Homo sapiens PCAF associated factor 65
beta protein.
Length = 589
Score = 105 bits (252), Expect = 4e-22
Identities = 78/256 (30%), Positives = 120/256 (46%), Gaps = 12/256 (4%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPV 302
N TE + IL+GH V + D +++ S D +IR W++ + T + + H PV
Sbjct: 330 NAGTE--MKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPV 387
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
L + P Y S S D+ W+F RT L + V +FHP+ T
Sbjct: 388 WDLDISPYSLYFASGSHDRTARLWSFD--RTYPLRIYAGHLADVDCV--KFHPNSNYLAT 443
Query: 360 GTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNF 419
G+ + V++W ++ ++V F GH GPV S++FS NG YLA+A ED +KLWDL +
Sbjct: 444 GSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLY 503
Query: 420 KTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK 477
K ++ + I L F +A A D VRV+ R + ++ GV G+
Sbjct: 504 KELRGHTD-NITSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQ 562
Query: 478 NAQYLASTSMDRTLKL 493
+ L+ M L L
Sbjct: 563 MSNVLSVQFMACNLLL 578
Score = 89.0 bits (211), Expect = 3e-17
Identities = 48/157 (30%), Positives = 80/157 (50%), Gaps = 4/157 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ LDI+P +G +DR A +++ D + I GH V V +HP+ + + T S
Sbjct: 387 VWDLDISPYS-LYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGS 445
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T+R+W+ + + H GPV L+ P G Y+ S DQ D+ +G L +
Sbjct: 446 TDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKE 505
Query: 337 VSDFSGVSLTTAQFHPD-GLIFGTGTENSQVKIWDLK 372
+ + ++T+ F PD GLI +NS V++WD++
Sbjct: 506 LRGHTD-NITSLTFSPDSGLIASASMDNS-VRVWDIR 540
Score = 80.2 bits (189), Expect = 2e-14
Identities = 47/190 (24%), Positives = 88/190 (46%), Gaps = 1/190 (0%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D S LL+ D + ++ + + +GH V + P + S D T R+W
Sbjct: 352 ADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLW 411
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+ + I H V + HP +Y+ + S+D+ + G + + G
Sbjct: 412 SFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPV 471
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
L+ A F P+G + E+ ++K+WDL + GH +TS++FS + +A+A+
Sbjct: 472 LSLA-FSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASM 530
Query: 405 DSCVKLWDLR 414
D+ V++WD+R
Sbjct: 531 DNSVRVWDIR 540
Score = 78.2 bits (184), Expect = 6e-14
Identities = 53/205 (25%), Positives = 87/205 (42%), Gaps = 4/205 (1%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPD 353
ILR H GPV +LS S D + D+ + T + + P
Sbjct: 337 ILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTN-TVLYQGHAYPVWDLDISPY 395
Query: 354 GLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
L F +G+ + ++W + + GH+ V + F N YLAT + D V+LW
Sbjct: 396 SLYFASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSA 455
Query: 414 RKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYL--CRQWQELKVFNDHTASAT 471
++ + + + L F +G YLA AG D R+ L K HT + T
Sbjct: 456 QQGNSVRLFTGHRG-PVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNIT 514
Query: 472 GVRFGKNAQYLASTSMDRTLKLYGI 496
+ F ++ +AS SMD +++++ I
Sbjct: 515 SLTFSPDSGLIASASMDNSVRVWDI 539
Score = 56.8 bits (131), Expect = 2e-07
Identities = 34/118 (28%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH GPV S F + L + +ED ++ WDL N Q Y + +L Y
Sbjct: 340 GHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQ-GHAYPVWDLDISPYSLY 398
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A D R++ + L+++ H A V+F N+ YLA+ S D+T++L+ +
Sbjct: 399 FASGSHDRTARLWSFDRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQ 456
Score = 46.8 bits (106), Expect = 2e-04
Identities = 21/77 (27%), Positives = 44/77 (57%), Gaps = 1/77 (1%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+LSL +P+ L + G D+ +++ + + L+GHT +T + + PD + +AS
Sbjct: 471 VLSLAFSPNG-KYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASAS 529
Query: 277 PDHTIRVWNVPTSQTTA 293
D+++RVW++ + +A
Sbjct: 530 MDNSVRVWDIRNTYCSA 546
Score = 31.5 bits (68), Expect = 7.1
Identities = 11/30 (36%), Positives = 18/30 (60%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQ 374
L TA+ PD + G +NS +K+W L+ +
Sbjct: 271 LNTAEISPDSKLLAAGFDNSCIKLWSLRSK 300
>BC036377-1|AAH36377.1| 415|Homo sapiens WD repeat domain 69
protein.
Length = 415
Score = 105 bits (251), Expect = 5e-22
Identities = 66/282 (23%), Positives = 125/282 (44%), Gaps = 8/282 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ ++ N K+ TG D+ +++ +T + +GHT ++ + ++P V T S
Sbjct: 137 VYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGS 196
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T ++W++ + LR H + LS + +GD +++ S D D TG+ K
Sbjct: 197 MDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGR---K 253
Query: 337 VSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
V+ G +++A F+ D + TG+ + K+WD VA GH + F
Sbjct: 254 VNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDY 313
Query: 395 NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVY 452
G +ATA+ D +++ K ++ E I ++ F+ G +L +D R++
Sbjct: 314 TGKLIATASADGTARIFSAATRKCIAKLEGHEG-EISKISFNPQGNHLLTGSSDKTARIW 372
Query: 453 LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ Q L+V HT F + + S D T +++
Sbjct: 373 DAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 98.3 bits (234), Expect = 5e-20
Identities = 69/286 (24%), Positives = 127/286 (44%), Gaps = 6/286 (2%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIY-HPDED 270
A + + ++ +N S S +TG DR +++ + + + L+GH V + + +P D
Sbjct: 90 AHILPLTNVALNKSG-SCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
+ T S D T ++W+V T + R H + LS +P V + S D DI+
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G+ + + S + + F+ G TG+ + V +WD V GH ++S
Sbjct: 209 GEEVYTLRGHS-AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSA 267
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-- 448
SF+ + + T + D KLWD K T+ ++ I + CFD +G +A A D
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDD-EILDSCFDYTGKLIATASADGT 326
Query: 449 VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
R++ + + H + + F +L + S D+T +++
Sbjct: 327 ARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
Score = 76.6 bits (180), Expect = 2e-13
Identities = 49/203 (24%), Positives = 94/203 (46%), Gaps = 3/203 (1%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPD 353
+L++H P+T ++L+ +G ++ S D+ D +G+ L + V A +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 354 GLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
G TG+ + K+W ++ F GH + +SF+ +AT + D+ KLWD+
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 414 RKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASAT 471
+ + T++ + I L F+ SG + D V V+ +++ + H A +
Sbjct: 207 QNGEEVYTLR-GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 472 GVRFGKNAQYLASTSMDRTLKLY 494
F + + + SMD+T KL+
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLW 288
Score = 75.4 bits (177), Expect = 4e-13
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 2/162 (1%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSL-HPT 310
+LK H +T V + IT S D T ++W+ + + L H V ++ +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 311 GDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWD 370
GD + + S D+ + TG+ + + F+P + TG+ ++ K+WD
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDTTAKLWD 205
Query: 371 LKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
++ V GH + S+SF+ +G + T + D V +WD
Sbjct: 206 IQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD 247
Score = 51.6 bits (118), Expect = 6e-06
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 4/164 (2%)
Query: 334 LTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
L KV + LT + G F TG+ + K+WD + GH V +I+F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 394 E-NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VR 450
G +AT + D KLW + K + T + I L F+ T +A D +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFR-GHTAEIVCLSFNPQSTLVATGSMDTTAK 202
Query: 451 VYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++ + +E+ H+A + F + + + S D T+ ++
Sbjct: 203 LWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 46.8 bits (106), Expect = 2e-04
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H+ P+T+++ +++G T + D KLWD + T++ N + G +
Sbjct: 91 HILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKI 150
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A D +++ + F HTA + F + +A+ SMD T KL+ I+
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
>AK097409-1|BAC05039.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ40090 fis, clone TESTI2003596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 415
Score = 105 bits (251), Expect = 5e-22
Identities = 66/282 (23%), Positives = 125/282 (44%), Gaps = 8/282 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ ++ N K+ TG D+ +++ +T + +GHT ++ + ++P V T S
Sbjct: 137 VYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGS 196
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T ++W++ + LR H + LS + +GD +++ S D D TG+ K
Sbjct: 197 MDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGR---K 253
Query: 337 VSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
V+ G +++A F+ D + TG+ + K+WD VA GH + F
Sbjct: 254 VNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDY 313
Query: 395 NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVY 452
G +ATA+ D +++ K ++ E I ++ F+ G +L +D R++
Sbjct: 314 TGKLIATASADGTARIFSAATRKCIAKLEGHEG-EISKISFNPQGNHLLTGSSDKTARIW 372
Query: 453 LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ Q L+V HT F + + S D T +++
Sbjct: 373 DAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 98.3 bits (234), Expect = 5e-20
Identities = 69/286 (24%), Positives = 127/286 (44%), Gaps = 6/286 (2%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIY-HPDED 270
A + + ++ +N S S +TG DR +++ + + + L+GH V + + +P D
Sbjct: 90 AHILPLTNVALNKSG-SCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
+ T S D T ++W+V T + R H + LS +P V + S D DI+
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G+ + + S + + F+ G TG+ + V +WD V GH ++S
Sbjct: 209 GEEVYTLRGHS-AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSA 267
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-- 448
SF+ + + T + D KLWD K T+ ++ I + CFD +G +A A D
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDD-EILDSCFDYTGKLIATASADGT 326
Query: 449 VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
R++ + + H + + F +L + S D+T +++
Sbjct: 327 ARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
Score = 76.6 bits (180), Expect = 2e-13
Identities = 49/203 (24%), Positives = 94/203 (46%), Gaps = 3/203 (1%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPD 353
+L++H P+T ++L+ +G ++ S D+ D +G+ L + V A +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 354 GLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
G TG+ + K+W ++ F GH + +SF+ +AT + D+ KLWD+
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 414 RKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASAT 471
+ + T++ + I L F+ SG + D V V+ +++ + H A +
Sbjct: 207 QNGEEVYTLR-GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 472 GVRFGKNAQYLASTSMDRTLKLY 494
F + + + SMD+T KL+
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLW 288
Score = 75.4 bits (177), Expect = 4e-13
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 2/162 (1%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSL-HPT 310
+LK H +T V + IT S D T ++W+ + + L H V ++ +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 311 GDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWD 370
GD + + S D+ + TG+ + + F+P + TG+ ++ K+WD
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDTTAKLWD 205
Query: 371 LKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
++ V GH + S+SF+ +G + T + D V +WD
Sbjct: 206 IQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD 247
Score = 51.6 bits (118), Expect = 6e-06
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 4/164 (2%)
Query: 334 LTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
L KV + LT + G F TG+ + K+WD + GH V +I+F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 394 E-NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VR 450
G +AT + D KLW + K + T + I L F+ T +A D +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFR-GHTAEIVCLSFNPQSTLVATGSMDTTAK 202
Query: 451 VYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++ + +E+ H+A + F + + + S D T+ ++
Sbjct: 203 LWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 46.8 bits (106), Expect = 2e-04
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H+ P+T+++ +++G T + D KLWD + T++ N + G +
Sbjct: 91 HILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKI 150
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A D +++ + F HTA + F + +A+ SMD T KL+ I+
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
>AC073065-2|AAX93215.1| 415|Homo sapiens unknown protein.
Length = 415
Score = 105 bits (251), Expect = 5e-22
Identities = 66/282 (23%), Positives = 125/282 (44%), Gaps = 8/282 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ ++ N K+ TG D+ +++ +T + +GHT ++ + ++P V T S
Sbjct: 137 VYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGS 196
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T ++W++ + LR H + LS + +GD +++ S D D TG+ K
Sbjct: 197 MDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGR---K 253
Query: 337 VSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
V+ G +++A F+ D + TG+ + K+WD VA GH + F
Sbjct: 254 VNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDY 313
Query: 395 NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVY 452
G +ATA+ D +++ K ++ E I ++ F+ G +L +D R++
Sbjct: 314 TGKLIATASADGTARIFSAATRKCIAKLEGHEG-EISKISFNPQGNHLLTGSSDKTARIW 372
Query: 453 LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ Q L+V HT F + + S D T +++
Sbjct: 373 DAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKDNTCRIW 414
Score = 98.3 bits (234), Expect = 5e-20
Identities = 69/286 (24%), Positives = 127/286 (44%), Gaps = 6/286 (2%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIY-HPDED 270
A + + ++ +N S S +TG DR +++ + + + L+GH V + + +P D
Sbjct: 90 AHILPLTNVALNKSG-SCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
+ T S D T ++W+V T + R H + LS +P V + S D DI+
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G+ + + S + + F+ G TG+ + V +WD V GH ++S
Sbjct: 209 GEEVYTLRGHS-AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSA 267
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-- 448
SF+ + + T + D KLWD K T+ ++ I + CFD +G +A A D
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDD-EILDSCFDYTGKLIATASADGT 326
Query: 449 VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
R++ + + H + + F +L + S D+T +++
Sbjct: 327 ARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
Score = 76.6 bits (180), Expect = 2e-13
Identities = 49/203 (24%), Positives = 94/203 (46%), Gaps = 3/203 (1%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPD 353
+L++H P+T ++L+ +G ++ S D+ D +G+ L + V A +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 354 GLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
G TG+ + K+W ++ F GH + +SF+ +AT + D+ KLWD+
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 414 RKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASAT 471
+ + T++ + I L F+ SG + D V V+ +++ + H A +
Sbjct: 207 QNGEEVYTLR-GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 472 GVRFGKNAQYLASTSMDRTLKLY 494
F + + + SMD+T KL+
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLW 288
Score = 75.4 bits (177), Expect = 4e-13
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 2/162 (1%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSL-HPT 310
+LK H +T V + IT S D T ++W+ + + L H V ++ +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 311 GDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWD 370
GD + + S D+ + TG+ + + F+P + TG+ ++ K+WD
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDTTAKLWD 205
Query: 371 LKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
++ V GH + S+SF+ +G + T + D V +WD
Sbjct: 206 IQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD 247
Score = 51.6 bits (118), Expect = 6e-06
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 4/164 (2%)
Query: 334 LTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
L KV + LT + G F TG+ + K+WD + GH V +I+F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFN 143
Query: 394 E-NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VR 450
G +AT + D KLW + K + T + I L F+ T +A D +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFR-GHTAEIVCLSFNPQSTLVATGSMDTTAK 202
Query: 451 VYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++ + +E+ H+A + F + + + S D T+ ++
Sbjct: 203 LWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 46.8 bits (106), Expect = 2e-04
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H+ P+T+++ +++G T + D KLWD + T++ N + G +
Sbjct: 91 HILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKI 150
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A D +++ + F HTA + F + +A+ SMD T KL+ I+
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
>X95525-1|CAA64777.1| 799|Homo sapiens hTAFII100 protein.
Length = 799
Score = 104 bits (249), Expect = 8e-22
Identities = 76/266 (28%), Positives = 125/266 (46%), Gaps = 16/266 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S + +D + ++ T + IL GH+ V + PD + ++++S D T+R+W
Sbjct: 511 SDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFS 341
++ T + H+ PV P G Y +S D+ WA + ++ +
Sbjct: 571 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFA--GHLA 628
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
V+ T +FHP+ TG+ + V++WD+ + V F GH GP+ S++FS NG +LAT
Sbjct: 629 DVNCT--RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 686
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A D V LWD+ ++ + + L F + G LA D V R W +K
Sbjct: 687 GATDGRVLLWDIGHGLMVGELKGHTD-TVCSLRFSRDGEILASGSMDNTV---RLWDAIK 742
Query: 462 VF----NDHTASATG-VRFGKNAQYL 482
F D +ATG + +N+Q L
Sbjct: 743 AFEDLETDDFTTATGHINLPENSQEL 768
Score = 103 bits (248), Expect = 1e-21
Identities = 82/281 (29%), Positives = 123/281 (43%), Gaps = 16/281 (5%)
Query: 216 GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
G+ ++D+ +D S L+ GG F T +V ++ KK+ V D +
Sbjct: 472 GLTAVDV--TDDSSLIAGG-------FADSTVRVWSVTP---KKLRSVKQASDLSLIDKE 519
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
S D R+ + T+ IL H GPV G S P +Y+LS+S D ++T L
Sbjct: 520 SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLV 579
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
+ + QF P G F +G + ++W + F GH+ V F N
Sbjct: 580 GYKGHN-YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 638
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR 455
Y+AT + D V+LWD+ N I I L F +G +LA TD RV L
Sbjct: 639 SNYVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 456 QWQELKV--FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
L V HT + +RF ++ + LAS SMD T++L+
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 75.4 bits (177), Expect = 4e-13
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 3/132 (2%)
Query: 367 KIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEE 426
+I D K S + GH GPV SFS + YL +++ED V+LW L+ +
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYK-GH 584
Query: 427 NYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLAS 484
NY + + F G Y G D R++ +Q L++F H A RF N+ Y+A+
Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 644
Query: 485 TSMDRTLKLYGI 496
S DRT++L+ +
Sbjct: 645 GSADRTVRLWDV 656
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/241 (23%), Positives = 101/241 (41%), Gaps = 19/241 (7%)
Query: 260 VTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS 319
+T V D + D T+RVW+V + ++ ++ D LSL + S
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASD-----LSL------IDKESD 521
Query: 320 DQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
D D +T L + SG + A F PD + +E+ V++W L+ + +
Sbjct: 522 DVLERIMDEKTASELKILYGHSG-PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC--FDQ 437
+ GH PV FS GYY + D +LW +++ +++ + C F
Sbjct: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHP 637
Query: 438 SGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYG 495
+ Y+A D VR++ +++F H + F N ++LA+ + D + L+
Sbjct: 638 NSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 496 I 496
I
Sbjct: 698 I 698
Score = 33.1 bits (72), Expect = 2.3
Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
Query: 387 VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAG 446
+T++ +++ +A DS V++W + K ++++ + ++ + +S L
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQASDLSLID---KESDDVLE--- 525
Query: 447 TDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
R+ + ELK+ H+ G F + YL S+S D T++L+ ++
Sbjct: 526 ---RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ 573
>U80191-1|AAC51215.1| 800|Homo sapiens TFIID subunit TAFII100
protein.
Length = 800
Score = 104 bits (249), Expect = 8e-22
Identities = 76/266 (28%), Positives = 125/266 (46%), Gaps = 16/266 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S + +D + ++ T + IL GH+ V + PD + ++++S D T+R+W
Sbjct: 511 SDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFS 341
++ T + H+ PV P G Y +S D+ WA + ++ +
Sbjct: 571 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFA--GHLA 628
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
V+ T +FHP+ TG+ + V++WD+ + V F GH GP+ S++FS NG +LAT
Sbjct: 629 DVNCT--RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 686
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A D V LWD+ ++ + + L F + G LA D V R W +K
Sbjct: 687 GATDGRVLLWDIGHGLMVGELKGHTD-TVCSLRFSRDGEILASGSMDNTV---RLWDAIK 742
Query: 462 VF----NDHTASATG-VRFGKNAQYL 482
F D +ATG + +N+Q L
Sbjct: 743 AFEDLETDDFTTATGHINLPENSQEL 768
Score = 103 bits (248), Expect = 1e-21
Identities = 82/281 (29%), Positives = 123/281 (43%), Gaps = 16/281 (5%)
Query: 216 GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
G+ ++D+ +D S L+ GG F T +V ++ KK+ V D +
Sbjct: 472 GLTAVDV--TDDSSLIAGG-------FADSTVRVWSVTP---KKLRSVKQASDLSLIDKE 519
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
S D R+ + T+ IL H GPV G S P +Y+LS+S D ++T L
Sbjct: 520 SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLV 579
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
+ + QF P G F +G + ++W + F GH+ V F N
Sbjct: 580 GYKGHN-YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 638
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR 455
Y+AT + D V+LWD+ N I I L F +G +LA TD RV L
Sbjct: 639 SNYVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 456 QWQELKV--FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
L V HT + +RF ++ + LAS SMD T++L+
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 75.4 bits (177), Expect = 4e-13
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 3/132 (2%)
Query: 367 KIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEE 426
+I D K S + GH GPV SFS + YL +++ED V+LW L+ +
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYK-GH 584
Query: 427 NYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLAS 484
NY + + F G Y G D R++ +Q L++F H A RF N+ Y+A+
Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 644
Query: 485 TSMDRTLKLYGI 496
S DRT++L+ +
Sbjct: 645 GSADRTVRLWDV 656
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/241 (23%), Positives = 101/241 (41%), Gaps = 19/241 (7%)
Query: 260 VTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS 319
+T V D + D T+RVW+V + ++ ++ D LSL + S
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASD-----LSL------IDKESD 521
Query: 320 DQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
D D +T L + SG + A F PD + +E+ V++W L+ + +
Sbjct: 522 DVLERIMDEKTASELKILYGHSG-PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC--FDQ 437
+ GH PV FS GYY + D +LW +++ +++ + C F
Sbjct: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHP 637
Query: 438 SGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYG 495
+ Y+A D VR++ +++F H + F N ++LA+ + D + L+
Sbjct: 638 NSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 496 I 496
I
Sbjct: 698 I 698
Score = 33.1 bits (72), Expect = 2.3
Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
Query: 387 VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAG 446
+T++ +++ +A DS V++W + K ++++ + ++ + +S L
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQASDLSLID---KESDDVLE--- 525
Query: 447 TDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
R+ + ELK+ H+ G F + YL S+S D T++L+ ++
Sbjct: 526 ---RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ 573
>U75309-1|AAC50902.1| 801|Homo sapiens TBP-associated factor
protein.
Length = 801
Score = 104 bits (249), Expect = 8e-22
Identities = 76/266 (28%), Positives = 125/266 (46%), Gaps = 16/266 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S + +D + ++ T + IL GH+ V + PD + ++++S D T+R+W
Sbjct: 512 SDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 571
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFS 341
++ T + H+ PV P G Y +S D+ WA + ++ +
Sbjct: 572 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFA--GHLA 629
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
V+ T +FHP+ TG+ + V++WD+ + V F GH GP+ S++FS NG +LAT
Sbjct: 630 DVNCT--RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 687
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A D V LWD+ ++ + + L F + G LA D V R W +K
Sbjct: 688 GATDGRVLLWDIGHGLMVGELKGHTD-TVCSLRFSRDGEILASGSMDNTV---RLWDAIK 743
Query: 462 VF----NDHTASATG-VRFGKNAQYL 482
F D +ATG + +N+Q L
Sbjct: 744 AFEDLETDDFTTATGHINLPENSQEL 769
Score = 103 bits (248), Expect = 1e-21
Identities = 82/281 (29%), Positives = 123/281 (43%), Gaps = 16/281 (5%)
Query: 216 GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
G+ ++D+ +D S L+ GG F T +V ++ KK+ V D +
Sbjct: 473 GLTAVDV--TDDSSLIAGG-------FADSTVRVWSVTP---KKLRSVKQASDLSLIDKE 520
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
S D R+ + T+ IL H GPV G S P +Y+LS+S D ++T L
Sbjct: 521 SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLV 580
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
+ + QF P G F +G + ++W + F GH+ V F N
Sbjct: 581 GYKGHN-YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 639
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR 455
Y+AT + D V+LWD+ N I I L F +G +LA TD RV L
Sbjct: 640 SNYVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 698
Query: 456 QWQELKV--FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
L V HT + +RF ++ + LAS SMD T++L+
Sbjct: 699 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 739
Score = 75.4 bits (177), Expect = 4e-13
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 3/132 (2%)
Query: 367 KIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEE 426
+I D K S + GH GPV SFS + YL +++ED V+LW L+ +
Sbjct: 527 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYK-GH 585
Query: 427 NYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLAS 484
NY + + F G Y G D R++ +Q L++F H A RF N+ Y+A+
Sbjct: 586 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 645
Query: 485 TSMDRTLKLYGI 496
S DRT++L+ +
Sbjct: 646 GSADRTVRLWDV 657
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/241 (23%), Positives = 101/241 (41%), Gaps = 19/241 (7%)
Query: 260 VTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS 319
+T V D + D T+RVW+V + ++ ++ D LSL + S
Sbjct: 474 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASD-----LSL------IDKESD 522
Query: 320 DQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
D D +T L + SG + A F PD + +E+ V++W L+ + +
Sbjct: 523 DVLERIMDEKTASELKILYGHSG-PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 581
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC--FDQ 437
+ GH PV FS GYY + D +LW +++ +++ + C F
Sbjct: 582 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHP 638
Query: 438 SGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYG 495
+ Y+A D VR++ +++F H + F N ++LA+ + D + L+
Sbjct: 639 NSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 698
Query: 496 I 496
I
Sbjct: 699 I 699
Score = 33.1 bits (72), Expect = 2.3
Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
Query: 387 VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAG 446
+T++ +++ +A DS V++W + K ++++ + ++ + +S L
Sbjct: 474 LTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQASDLSLID---KESDDVLE--- 526
Query: 447 TDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
R+ + ELK+ H+ G F + YL S+S D T++L+ ++
Sbjct: 527 ---RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ 574
>BC052268-1|AAH52268.2| 800|Homo sapiens TAF5 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 104 bits (249), Expect = 8e-22
Identities = 76/266 (28%), Positives = 125/266 (46%), Gaps = 16/266 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S + +D + ++ T + IL GH+ V + PD + ++++S D T+R+W
Sbjct: 511 SDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFS 341
++ T + H+ PV P G Y +S D+ WA + ++ +
Sbjct: 571 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFA--GHLA 628
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
V+ T +FHP+ TG+ + V++WD+ + V F GH GP+ S++FS NG +LAT
Sbjct: 629 DVNCT--RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 686
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A D V LWD+ ++ + + L F + G LA D V R W +K
Sbjct: 687 GATDGRVLLWDIGHGLMVGELKGHTD-TVCSLRFSRDGEILASGSMDNTV---RLWDAIK 742
Query: 462 VF----NDHTASATG-VRFGKNAQYL 482
F D +ATG + +N+Q L
Sbjct: 743 AFEDLETDDFTTATGHINLPENSQEL 768
Score = 103 bits (248), Expect = 1e-21
Identities = 82/281 (29%), Positives = 123/281 (43%), Gaps = 16/281 (5%)
Query: 216 GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
G+ ++D+ +D S L+ GG F T +V ++ KK+ V D +
Sbjct: 472 GLTAVDV--TDDSSLIAGG-------FADSTVRVWSVTP---KKLRSVKQASDLSLIDKE 519
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
S D R+ + T+ IL H GPV G S P +Y+LS+S D ++T L
Sbjct: 520 SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLV 579
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
+ + QF P G F +G + ++W + F GH+ V F N
Sbjct: 580 GYKGHN-YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 638
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR 455
Y+AT + D V+LWD+ N I I L F +G +LA TD RV L
Sbjct: 639 SNYVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 456 QWQELKV--FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
L V HT + +RF ++ + LAS SMD T++L+
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 75.4 bits (177), Expect = 4e-13
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 3/132 (2%)
Query: 367 KIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEE 426
+I D K S + GH GPV SFS + YL +++ED V+LW L+ +
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYK-GH 584
Query: 427 NYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLAS 484
NY + + F G Y G D R++ +Q L++F H A RF N+ Y+A+
Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 644
Query: 485 TSMDRTLKLYGI 496
S DRT++L+ +
Sbjct: 645 GSADRTVRLWDV 656
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/241 (23%), Positives = 101/241 (41%), Gaps = 19/241 (7%)
Query: 260 VTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS 319
+T V D + D T+RVW+V + ++ ++ D LSL + S
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASD-----LSL------IDKESD 521
Query: 320 DQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
D D +T L + SG + A F PD + +E+ V++W L+ + +
Sbjct: 522 DVLERIMDEKTASELKILYGHSG-PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC--FDQ 437
+ GH PV FS GYY + D +LW +++ +++ + C F
Sbjct: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHP 637
Query: 438 SGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYG 495
+ Y+A D VR++ +++F H + F N ++LA+ + D + L+
Sbjct: 638 NSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 496 I 496
I
Sbjct: 698 I 698
Score = 33.1 bits (72), Expect = 2.3
Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
Query: 387 VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAG 446
+T++ +++ +A DS V++W + K ++++ + ++ + +S L
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQASDLSLID---KESDDVLE--- 525
Query: 447 TDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
R+ + ELK+ H+ G F + YL S+S D T++L+ ++
Sbjct: 526 ---RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ 573
>AL591408-4|CAI16747.1| 800|Homo sapiens TAF5 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 100kD
protein.
Length = 800
Score = 104 bits (249), Expect = 8e-22
Identities = 76/266 (28%), Positives = 125/266 (46%), Gaps = 16/266 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S + +D + ++ T + IL GH+ V + PD + ++++S D T+R+W
Sbjct: 511 SDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 570
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFS 341
++ T + H+ PV P G Y +S D+ WA + ++ +
Sbjct: 571 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFA--GHLA 628
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
V+ T +FHP+ TG+ + V++WD+ + V F GH GP+ S++FS NG +LAT
Sbjct: 629 DVNCT--RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 686
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A D V LWD+ ++ + + L F + G LA D V R W +K
Sbjct: 687 GATDGRVLLWDIGHGLMVGELKGHTD-TVCSLRFSRDGEILASGSMDNTV---RLWDAIK 742
Query: 462 VF----NDHTASATG-VRFGKNAQYL 482
F D +ATG + +N+Q L
Sbjct: 743 AFEDLETDDFTTATGHINLPENSQEL 768
Score = 103 bits (248), Expect = 1e-21
Identities = 82/281 (29%), Positives = 123/281 (43%), Gaps = 16/281 (5%)
Query: 216 GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
G+ ++D+ +D S L+ GG F T +V ++ KK+ V D +
Sbjct: 472 GLTAVDV--TDDSSLIAGG-------FADSTVRVWSVTP---KKLRSVKQASDLSLIDKE 519
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
S D R+ + T+ IL H GPV G S P +Y+LS+S D ++T L
Sbjct: 520 SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLV 579
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
+ + QF P G F +G + ++W + F GH+ V F N
Sbjct: 580 GYKGHN-YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 638
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR 455
Y+AT + D V+LWD+ N I I L F +G +LA TD RV L
Sbjct: 639 SNYVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 456 QWQELKV--FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
L V HT + +RF ++ + LAS SMD T++L+
Sbjct: 698 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 738
Score = 75.4 bits (177), Expect = 4e-13
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 3/132 (2%)
Query: 367 KIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEE 426
+I D K S + GH GPV SFS + YL +++ED V+LW L+ +
Sbjct: 526 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYK-GH 584
Query: 427 NYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLAS 484
NY + + F G Y G D R++ +Q L++F H A RF N+ Y+A+
Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 644
Query: 485 TSMDRTLKLYGI 496
S DRT++L+ +
Sbjct: 645 GSADRTVRLWDV 656
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/241 (23%), Positives = 101/241 (41%), Gaps = 19/241 (7%)
Query: 260 VTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS 319
+T V D + D T+RVW+V + ++ ++ D LSL + S
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASD-----LSL------IDKESD 521
Query: 320 DQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
D D +T L + SG + A F PD + +E+ V++W L+ + +
Sbjct: 522 DVLERIMDEKTASELKILYGHSG-PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 580
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC--FDQ 437
+ GH PV FS GYY + D +LW +++ +++ + C F
Sbjct: 581 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHP 637
Query: 438 SGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYG 495
+ Y+A D VR++ +++F H + F N ++LA+ + D + L+
Sbjct: 638 NSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 697
Query: 496 I 496
I
Sbjct: 698 I 698
Score = 33.1 bits (72), Expect = 2.3
Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
Query: 387 VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAG 446
+T++ +++ +A DS V++W + K ++++ + ++ + +S L
Sbjct: 473 LTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQASDLSLID---KESDDVLE--- 525
Query: 447 TDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
R+ + ELK+ H+ G F + YL S+S D T++L+ ++
Sbjct: 526 ---RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ 573
>AK223615-1|BAD97335.1| 803|Homo sapiens Transcription initiation
factor TFIID subunit 5 variant protein.
Length = 803
Score = 104 bits (249), Expect = 8e-22
Identities = 76/266 (28%), Positives = 125/266 (46%), Gaps = 16/266 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S + +D + ++ T + IL GH+ V + PD + ++++S D T+R+W
Sbjct: 514 SDLSLIDKESDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLW 573
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFS 341
++ T + H+ PV P G Y +S D+ WA + ++ +
Sbjct: 574 SLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFA--GHLA 631
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
V+ T +FHP+ TG+ + V++WD+ + V F GH GP+ S++FS NG +LAT
Sbjct: 632 DVNCT--RFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLAT 689
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A D V LWD+ ++ + + L F + G LA D V R W +K
Sbjct: 690 GATDGRVLLWDIGHGLMVGELKGHTD-TVCSLRFSRDGEILASGSMDNTV---RLWDAIK 745
Query: 462 VF----NDHTASATG-VRFGKNAQYL 482
F D +ATG + +N+Q L
Sbjct: 746 AFEDLETDDFTTATGHINLPENSQEL 771
Score = 103 bits (248), Expect = 1e-21
Identities = 82/281 (29%), Positives = 123/281 (43%), Gaps = 16/281 (5%)
Query: 216 GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
G+ ++D+ +D S L+ GG F T +V ++ KK+ V D +
Sbjct: 475 GLTAVDV--TDDSSLIAGG-------FADSTVRVWSVTP---KKLRSVKQASDLSLIDKE 522
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
S D R+ + T+ IL H GPV G S P +Y+LS+S D ++T L
Sbjct: 523 SDDVLERIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLV 582
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
+ + QF P G F +G + ++W + F GH+ V F N
Sbjct: 583 GYKGHN-YPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPN 641
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR 455
Y+AT + D V+LWD+ N I I L F +G +LA TD RV L
Sbjct: 642 SNYVATGSADRTVRLWDVLN-GNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 700
Query: 456 QWQELKV--FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
L V HT + +RF ++ + LAS SMD T++L+
Sbjct: 701 IGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLW 741
Score = 75.4 bits (177), Expect = 4e-13
Identities = 43/132 (32%), Positives = 66/132 (50%), Gaps = 3/132 (2%)
Query: 367 KIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEE 426
+I D K S + GH GPV SFS + YL +++ED V+LW L+ +
Sbjct: 529 RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYK-GH 587
Query: 427 NYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLAS 484
NY + + F G Y G D R++ +Q L++F H A RF N+ Y+A+
Sbjct: 588 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 647
Query: 485 TSMDRTLKLYGI 496
S DRT++L+ +
Sbjct: 648 GSADRTVRLWDV 659
Score = 66.1 bits (154), Expect = 3e-10
Identities = 56/241 (23%), Positives = 101/241 (41%), Gaps = 19/241 (7%)
Query: 260 VTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS 319
+T V D + D T+RVW+V + ++ ++ D LSL + S
Sbjct: 476 LTAVDVTDDSSLIAGGFADSTVRVWSVTPKKLRSVKQASD-----LSL------IDKESD 524
Query: 320 DQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
D D +T L + SG + A F PD + +E+ V++W L+ + +
Sbjct: 525 DVLERIMDEKTASELKILYGHSG-PVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVG 583
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC--FDQ 437
+ GH PV FS GYY + D +LW +++ +++ + C F
Sbjct: 584 YKGHNYPVWDTQFSPYGYYFVSGGHDRVARLW---ATDHYQPLRIFAGHLADVNCTRFHP 640
Query: 438 SGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYG 495
+ Y+A D VR++ +++F H + F N ++LA+ + D + L+
Sbjct: 641 NSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWD 700
Query: 496 I 496
I
Sbjct: 701 I 701
Score = 33.1 bits (72), Expect = 2.3
Identities = 23/111 (20%), Positives = 53/111 (47%), Gaps = 10/111 (9%)
Query: 387 VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAG 446
+T++ +++ +A DS V++W + K ++++ + ++ + +S L
Sbjct: 476 LTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQASDLSLID---KESDDVLE--- 528
Query: 447 TDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
R+ + ELK+ H+ G F + YL S+S D T++L+ ++
Sbjct: 529 ---RIMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ 576
>AK075289-1|BAC11525.1| 407|Homo sapiens protein ( Homo sapiens
cDNA FLJ90808 fis, clone Y79AA1000777, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 407
Score = 104 bits (249), Expect = 8e-22
Identities = 68/268 (25%), Positives = 120/268 (44%), Gaps = 4/268 (1%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
+L +G D V++ + GH VT V + P + + S D T+R+W
Sbjct: 33 QLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNV 92
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTA 348
+ + R+H V + G ++ S D+ + L +S + A
Sbjct: 93 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCA 151
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
+F PDG + + +++ VK+WD + V ++ H G VT + F +G +A A D+ V
Sbjct: 152 KFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTV 211
Query: 409 KLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
K+WD+R + + QL + A+ L F SG YL A +D +++ + + L + H
Sbjct: 212 KVWDVRTYRLLQHYQL-HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 270
Query: 467 TASATGVRFGKNAQYLASTSMDRTLKLY 494
AT V F + +Y AS D + ++
Sbjct: 271 QGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 96.3 bits (229), Expect = 2e-19
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 1/187 (0%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD +T +D+ V+ ++ + L H V + PD +++AS D T+++W
Sbjct: 113 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+ + + H G VT + HP+G + + D D+RT +LL +
Sbjct: 173 DKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHY-QLHSAA 231
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+ FHP G T + +S +KI DL E + GH GP T+++FS G Y A+
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGS 291
Query: 405 DSCVKLW 411
D V +W
Sbjct: 292 DEQVMVW 298
Score = 92.7 bits (220), Expect = 3e-18
Identities = 64/242 (26%), Positives = 111/242 (45%), Gaps = 4/242 (1%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
KGH VT V + + + + S D + VW++ H VT ++ P+G
Sbjct: 16 KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 75
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKE 373
+ S S D+ + + + V ++ + F DG F T +++ VK+W
Sbjct: 76 LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 374 QSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKEL 433
Q + + H+ V FS +G + +A++D VKLWD + + E + +
Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYV 193
Query: 434 CFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTL 491
F SGT +A AG D V+V+ R ++ L+ + H+A+ G+ F + YL + S D TL
Sbjct: 194 DFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTL 253
Query: 492 KL 493
K+
Sbjct: 254 KI 255
Score = 84.2 bits (199), Expect = 9e-16
Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 5/160 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D +++ +D+ +++K + + V H VT V +HP + A D+T++VW+
Sbjct: 156 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V T + + H V GLS HP+G+Y+++ SSD D+ G+LL + G +
Sbjct: 216 VRTYRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPA- 274
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW----DLKEQSNVANFP 381
TT F G F +G + QV +W D+ + V P
Sbjct: 275 TTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVP 314
Score = 66.1 bits (154), Expect = 3e-10
Identities = 38/153 (24%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++T F + +G+ +S + +W +K QS F GH VT ++FS +G+ LA+ +
Sbjct: 21 AVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGS 80
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELK 461
D V++W + +K T+ ++ + F G A D V+V+ + + L
Sbjct: 81 RDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLF 139
Query: 462 VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ H +F + + + S S D+T+KL+
Sbjct: 140 SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Score = 60.9 bits (141), Expect = 1e-08
Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 7/157 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
++T F P G + +G+ + V+IW ++K +S V F H V S+ F +G T
Sbjct: 63 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT 120
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A++D VK+W + K ++ N+ ++ F G + A D V L +
Sbjct: 121 ASDDKTVKVWATHRQKFLFSLSQHINW-VRCAKFSPDGRLIVSASDDKTVKLWDKSSREC 179
Query: 462 VFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
V + +H T V F + +A+ MD T+K++ +
Sbjct: 180 VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216
Score = 56.8 bits (131), Expect = 2e-07
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQS 438
+F GH VT + FS N LA+ + DSC+ +W ++ ++ A+ + F S
Sbjct: 14 HFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKD-AVTCVNFSPS 72
Query: 439 GTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
G LA D VR+++ E VF HTA+ V F + Q + S D+T+K++
Sbjct: 73 GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
>BC119693-1|AAI19694.1| 441|Homo sapiens WDR51A protein protein.
Length = 441
Score = 103 bits (248), Expect = 1e-21
Identities = 81/320 (25%), Positives = 137/320 (42%), Gaps = 11/320 (3%)
Query: 183 RGRTLPEGLLAPEQIRAFLTLA---SHPGLH---SASVPGILSLDINPSDHSKLLTGGND 236
RGR L G P LTLA P L + +D + + +L +G D
Sbjct: 16 RGRVLALGKPLPHPGFTHLTLALSQEDPSLERHFKGHRDAVTCVDFSINT-KQLASGSMD 74
Query: 237 RNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILR 296
V++ + GH VT V + P + + S D T+R+W + + R
Sbjct: 75 SCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFR 134
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLI 356
+H V + G ++ S D+ + L +S + A+F PDG +
Sbjct: 135 AHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCAKFSPDGRL 193
Query: 357 FGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKL 416
+ +++ VK+WD + V ++ H G VT + F +G +A A D+ VK+WD+R
Sbjct: 194 IVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTH 253
Query: 417 KNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVR 474
+ + QL + A+ L F SG YL A +D +++ + + L + H AT V
Sbjct: 254 RLLQHYQL-HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVA 312
Query: 475 FGKNAQYLASTSMDRTLKLY 494
F + +Y AS D + ++
Sbjct: 313 FSRTGEYFASGGSDEQVMVW 332
Score = 84.6 bits (200), Expect = 7e-16
Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 5/160 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D +++ +D+ +++K + + V H VT V +HP + A D+T++VW+
Sbjct: 190 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 249
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V T + + H V GLS HP+G+Y+++ SSD D+ G+LL + G +
Sbjct: 250 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPA- 308
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW----DLKEQSNVANFP 381
TT F G F +G + QV +W D+ + V P
Sbjct: 309 TTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVP 348
Score = 60.9 bits (141), Expect = 1e-08
Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 7/157 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
++T F P G + +G+ + V+IW ++K +S V F H V S+ F +G T
Sbjct: 97 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT 154
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A++D VK+W + K ++ N+ ++ F G + A D V L +
Sbjct: 155 ASDDKTVKVWATHRQKFLFSLSQHINW-VRCAKFSPDGRLIVSASDDKTVKLWDKSSREC 213
Query: 462 VFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
V + +H T V F + +A+ MD T+K++ +
Sbjct: 214 VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDV 250
>BC119692-1|AAI19693.1| 407|Homo sapiens WD repeat domain 51A
protein.
Length = 407
Score = 103 bits (247), Expect = 1e-21
Identities = 68/268 (25%), Positives = 120/268 (44%), Gaps = 4/268 (1%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
+L +G D V++ + GH VT V + P + + S D T+R+W
Sbjct: 33 QLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNV 92
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTA 348
+ + R+H V + G ++ S D+ + L +S + A
Sbjct: 93 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCA 151
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
+F PDG + + +++ VK+WD + V ++ H G VT + F +G +A A D+ V
Sbjct: 152 KFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTV 211
Query: 409 KLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
K+WD+R + + QL + A+ L F SG YL A +D +++ + + L + H
Sbjct: 212 KVWDVRTHRLLQHYQL-HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 270
Query: 467 TASATGVRFGKNAQYLASTSMDRTLKLY 494
AT V F + +Y AS D + ++
Sbjct: 271 QGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 96.7 bits (230), Expect = 2e-19
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 1/187 (0%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD +T +D+ V+ ++ + L H V + PD +++AS D T+++W
Sbjct: 113 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+ + + H G VT + HP+G + + D D+RT +LL +
Sbjct: 173 DKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY-QLHSAA 231
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+ FHP G T + +S +KI DL E + GH GP T+++FS G Y A+
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGS 291
Query: 405 DSCVKLW 411
D V +W
Sbjct: 292 DEQVMVW 298
Score = 91.1 bits (216), Expect = 8e-18
Identities = 64/242 (26%), Positives = 110/242 (45%), Gaps = 4/242 (1%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
KGH VT V + + + + S D + VW++ H VT ++ P+G
Sbjct: 16 KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 75
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKE 373
+ S S D+ + + + V ++ + F DG F T +++ VK+W
Sbjct: 76 LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 374 QSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKEL 433
Q + + H+ V FS +G + +A++D VKLWD + + E + +
Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYV 193
Query: 434 CFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTL 491
F SGT +A AG D V+V+ R + L+ + H+A+ G+ F + YL + S D TL
Sbjct: 194 DFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTL 253
Query: 492 KL 493
K+
Sbjct: 254 KI 255
Score = 84.6 bits (200), Expect = 7e-16
Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 5/160 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D +++ +D+ +++K + + V H VT V +HP + A D+T++VW+
Sbjct: 156 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V T + + H V GLS HP+G+Y+++ SSD D+ G+LL + G +
Sbjct: 216 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPA- 274
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW----DLKEQSNVANFP 381
TT F G F +G + QV +W D+ + V P
Sbjct: 275 TTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVP 314
Score = 66.1 bits (154), Expect = 3e-10
Identities = 38/153 (24%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++T F + +G+ +S + +W +K QS F GH VT ++FS +G+ LA+ +
Sbjct: 21 AVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGS 80
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELK 461
D V++W + +K T+ ++ + F G A D V+V+ + + L
Sbjct: 81 RDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLF 139
Query: 462 VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ H +F + + + S S D+T+KL+
Sbjct: 140 SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Score = 60.9 bits (141), Expect = 1e-08
Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 7/157 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
++T F P G + +G+ + V+IW ++K +S V F H V S+ F +G T
Sbjct: 63 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT 120
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A++D VK+W + K ++ N+ ++ F G + A D V L +
Sbjct: 121 ASDDKTVKVWATHRQKFLFSLSQHINW-VRCAKFSPDGRLIVSASDDKTVKLWDKSSREC 179
Query: 462 VFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
V + +H T V F + +A+ MD T+K++ +
Sbjct: 180 VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216
Score = 56.8 bits (131), Expect = 2e-07
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQS 438
+F GH VT + FS N LA+ + DSC+ +W ++ ++ A+ + F S
Sbjct: 14 HFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKD-AVTCVNFSPS 72
Query: 439 GTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
G LA D VR+++ E VF HTA+ V F + Q + S D+T+K++
Sbjct: 73 GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
>BC110877-1|AAI10878.1| 359|Homo sapiens WDR51A protein protein.
Length = 359
Score = 103 bits (247), Expect = 1e-21
Identities = 68/268 (25%), Positives = 120/268 (44%), Gaps = 4/268 (1%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
+L +G D V++ + GH VT V + P + + S D T+R+W
Sbjct: 33 QLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNV 92
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTA 348
+ + R+H V + G ++ S D+ + L +S + A
Sbjct: 93 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCA 151
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
+F PDG + + +++ VK+WD + V ++ H G VT + F +G +A A D+ V
Sbjct: 152 KFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTV 211
Query: 409 KLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
K+WD+R + + QL + A+ L F SG YL A +D +++ + + L + H
Sbjct: 212 KVWDVRTHRLLQHYQL-HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 270
Query: 467 TASATGVRFGKNAQYLASTSMDRTLKLY 494
AT V F + +Y AS D + ++
Sbjct: 271 QGPATTVAFSRTGEYFASGGSDEQVMVW 298
Score = 96.7 bits (230), Expect = 2e-19
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 1/187 (0%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD +T +D+ V+ ++ + L H V + PD +++AS D T+++W
Sbjct: 113 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+ + + H G VT + HP+G + + D D+RT +LL +
Sbjct: 173 DKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY-QLHSAA 231
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+ FHP G T + +S +KI DL E + GH GP T+++FS G Y A+
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGS 291
Query: 405 DSCVKLW 411
D V +W
Sbjct: 292 DEQVMVW 298
Score = 91.1 bits (216), Expect = 8e-18
Identities = 64/242 (26%), Positives = 110/242 (45%), Gaps = 4/242 (1%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
KGH VT V + + + + S D + VW++ H VT ++ P+G
Sbjct: 16 KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 75
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKE 373
+ S S D+ + + + V ++ + F DG F T +++ VK+W
Sbjct: 76 LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 134
Query: 374 QSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKEL 433
Q + + H+ V FS +G + +A++D VKLWD + + E + +
Sbjct: 135 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYV 193
Query: 434 CFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTL 491
F SGT +A AG D V+V+ R + L+ + H+A+ G+ F + YL + S D TL
Sbjct: 194 DFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTL 253
Query: 492 KL 493
K+
Sbjct: 254 KI 255
Score = 84.6 bits (200), Expect = 7e-16
Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 5/160 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D +++ +D+ +++K + + V H VT V +HP + A D+T++VW+
Sbjct: 156 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 215
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V T + + H V GLS HP+G+Y+++ SSD D+ G+LL + G +
Sbjct: 216 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPA- 274
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW----DLKEQSNVANFP 381
TT F G F +G + QV +W D+ + V P
Sbjct: 275 TTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVP 314
Score = 66.1 bits (154), Expect = 3e-10
Identities = 38/153 (24%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++T F + +G+ +S + +W +K QS F GH VT ++FS +G+ LA+ +
Sbjct: 21 AVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGS 80
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELK 461
D V++W + +K T+ ++ + F G A D V+V+ + + L
Sbjct: 81 RDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLF 139
Query: 462 VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ H +F + + + S S D+T+KL+
Sbjct: 140 SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 172
Score = 60.9 bits (141), Expect = 1e-08
Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 7/157 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
++T F P G + +G+ + V+IW ++K +S V F H V S+ F +G T
Sbjct: 63 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT 120
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A++D VK+W + K ++ N+ ++ F G + A D V L +
Sbjct: 121 ASDDKTVKVWATHRQKFLFSLSQHINW-VRCAKFSPDGRLIVSASDDKTVKLWDKSSREC 179
Query: 462 VFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
V + +H T V F + +A+ MD T+K++ +
Sbjct: 180 VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDV 216
Score = 56.8 bits (131), Expect = 2e-07
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQS 438
+F GH VT + FS N LA+ + DSC+ +W ++ ++ A+ + F S
Sbjct: 14 HFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKD-AVTCVNFSPS 72
Query: 439 GTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
G LA D VR+++ E VF HTA+ V F + Q + S D+T+K++
Sbjct: 73 GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130
>BC007417-1|AAH07417.2| 396|Homo sapiens WDR51A protein protein.
Length = 396
Score = 103 bits (247), Expect = 1e-21
Identities = 68/268 (25%), Positives = 120/268 (44%), Gaps = 4/268 (1%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
+L +G D V++ + GH VT V + P + + S D T+R+W
Sbjct: 22 QLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNV 81
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTA 348
+ + R+H V + G ++ S D+ + L +S + A
Sbjct: 82 KGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCA 140
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
+F PDG + + +++ VK+WD + V ++ H G VT + F +G +A A D+ V
Sbjct: 141 KFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTV 200
Query: 409 KLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
K+WD+R + + QL + A+ L F SG YL A +D +++ + + L + H
Sbjct: 201 KVWDVRTHRLLQHYQL-HSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGH 259
Query: 467 TASATGVRFGKNAQYLASTSMDRTLKLY 494
AT V F + +Y AS D + ++
Sbjct: 260 QGPATTVAFSRTGEYFASGGSDEQVMVW 287
Score = 96.7 bits (230), Expect = 2e-19
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 1/187 (0%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD +T +D+ V+ ++ + L H V + PD +++AS D T+++W
Sbjct: 102 SDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 161
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+ + + H G VT + HP+G + + D D+RT +LL +
Sbjct: 162 DKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHY-QLHSAA 220
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+ FHP G T + +S +KI DL E + GH GP T+++FS G Y A+
Sbjct: 221 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGS 280
Query: 405 DSCVKLW 411
D V +W
Sbjct: 281 DEQVMVW 287
Score = 91.1 bits (216), Expect = 8e-18
Identities = 64/242 (26%), Positives = 110/242 (45%), Gaps = 4/242 (1%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
KGH VT V + + + + S D + VW++ H VT ++ P+G
Sbjct: 5 KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 64
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKE 373
+ S S D+ + + + V ++ + F DG F T +++ VK+W
Sbjct: 65 LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHR 123
Query: 374 QSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKEL 433
Q + + H+ V FS +G + +A++D VKLWD + + E + +
Sbjct: 124 QKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYV 182
Query: 434 CFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTL 491
F SGT +A AG D V+V+ R + L+ + H+A+ G+ F + YL + S D TL
Sbjct: 183 DFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTL 242
Query: 492 KL 493
K+
Sbjct: 243 KI 244
Score = 84.6 bits (200), Expect = 7e-16
Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 5/160 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D +++ +D+ +++K + + V H VT V +HP + A D+T++VW+
Sbjct: 145 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 204
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V T + + H V GLS HP+G+Y+++ SSD D+ G+LL + G +
Sbjct: 205 VRTHRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPA- 263
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW----DLKEQSNVANFP 381
TT F G F +G + QV +W D+ + V P
Sbjct: 264 TTVAFSRTGEYFASGGSDEQVMVWKSNFDIVDHGEVTKVP 303
Score = 66.1 bits (154), Expect = 3e-10
Identities = 38/153 (24%), Positives = 73/153 (47%), Gaps = 3/153 (1%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++T F + +G+ +S + +W +K QS F GH VT ++FS +G+ LA+ +
Sbjct: 10 AVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGS 69
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELK 461
D V++W + +K T+ ++ + F G A D V+V+ + + L
Sbjct: 70 RDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLF 128
Query: 462 VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ H +F + + + S S D+T+KL+
Sbjct: 129 SLSQHINWVRCAKFSPDGRLIVSASDDKTVKLW 161
Score = 60.9 bits (141), Expect = 1e-08
Identities = 41/157 (26%), Positives = 73/157 (46%), Gaps = 7/157 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
++T F P G + +G+ + V+IW ++K +S V F H V S+ F +G T
Sbjct: 52 AVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV--FRAHTATVRSVHFCSDGQSFVT 109
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
A++D VK+W + K ++ N+ ++ F G + A D V L +
Sbjct: 110 ASDDKTVKVWATHRQKFLFSLSQHINW-VRCAKFSPDGRLIVSASDDKTVKLWDKSSREC 168
Query: 462 VFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
V + +H T V F + +A+ MD T+K++ +
Sbjct: 169 VHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDV 205
Score = 56.8 bits (131), Expect = 2e-07
Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQS 438
+F GH VT + FS N LA+ + DSC+ +W ++ ++ A+ + F S
Sbjct: 3 HFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKD-AVTCVNFSPS 61
Query: 439 GTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
G LA D VR+++ E VF HTA+ V F + Q + S D+T+K++
Sbjct: 62 GHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 119
>AK098821-1|BAC05425.1| 415|Homo sapiens protein ( Homo sapiens
cDNA FLJ25955 fis, clone TST03904. ).
Length = 415
Score = 102 bits (244), Expect = 3e-21
Identities = 65/282 (23%), Positives = 124/282 (43%), Gaps = 8/282 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ ++ N K+ TG D+ +++ +T + +GHT ++ + ++P V T S
Sbjct: 137 VYAIAFNNPYGDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGS 196
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T ++W++ + LR H + LS + +GD +++ S D D TG+ K
Sbjct: 197 MDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGR---K 253
Query: 337 VSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
V+ G +++A F+ D + TG+ + K+WD VA GH + F
Sbjct: 254 VNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDY 313
Query: 395 NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVY 452
G +ATA+ D +++ K ++ E I ++ F+ G +L +D R++
Sbjct: 314 TGKLIATASADGTARIFSAATRKCIAKLEGHEG-EISKISFNPQGNHLLTGSSDKTARIW 372
Query: 453 LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ Q L+V HT F + + S T +++
Sbjct: 373 DAQTGQCLQVLEGHTDEIFSCAFNYKGNIVITGSKGNTCRIW 414
Score = 98.7 bits (235), Expect = 4e-20
Identities = 69/286 (24%), Positives = 127/286 (44%), Gaps = 6/286 (2%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIY-HPDED 270
A + + ++ +N S S +TG DR +++ + + + L+GH V + + +P D
Sbjct: 90 AHILPLTNVALNKSG-SCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
+ T S D T ++W+V T + R H + LS +P V + S D DI+
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G+ + + S + + F+ G TG+ + V +WD V GH ++S
Sbjct: 209 GEEVYTLRGHS-AEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSA 267
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-- 448
SF+ + + T + D KLWD K T+ ++ I + CFD +G +A A D
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDD-EILDSCFDYTGKLIATASADGT 326
Query: 449 VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
R++ + + H + + F +L + S D+T +++
Sbjct: 327 ARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
Score = 76.2 bits (179), Expect = 3e-13
Identities = 49/203 (24%), Positives = 94/203 (46%), Gaps = 3/203 (1%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPD 353
+L++H P+T ++L+ +G ++ S D+ D +G+ L + V A +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 354 GLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
G TG+ + K+W ++ F GH + +SF+ +AT + D+ KLWD+
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 414 RKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASAT 471
+ + T++ + I L F+ SG + D V V+ +++ + H A +
Sbjct: 207 QNGEEVYTLR-GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 472 GVRFGKNAQYLASTSMDRTLKLY 494
F + + + SMD+T KL+
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLW 288
Score = 74.5 bits (175), Expect = 8e-13
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 2/162 (1%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSL-HPT 310
+LK H +T V + IT S D T ++W+ + + L H V ++ +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 311 GDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWD 370
GD + + S D+ + TG+ + + F+P + TG+ ++ K+WD
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDTTAKLWD 205
Query: 371 LKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
++ V GH + S+SF+ +G + T + D V +WD
Sbjct: 206 IQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD 247
Score = 51.2 bits (117), Expect = 8e-06
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 4/164 (2%)
Query: 334 LTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
L KV + LT + G F TG+ + K+WD + GH V +I+F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFN 143
Query: 394 E-NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VR 450
G +AT + D KLW + K + T + I L F+ T +A D +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFR-GHTAEIVCLSFNPQSTLVATGSMDTTAK 202
Query: 451 VYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++ + +E+ H+A + F + + + S D T+ ++
Sbjct: 203 LWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H+ P+T+++ +++G T + D KLWD + T++ N + G +
Sbjct: 91 HILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGDKI 150
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A D +++ + F HTA + F + +A+ SMD T KL+ I+
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
>EF011619-1|ABK41109.1| 478|Homo sapiens CDW9/WDR51B protein.
Length = 478
Score = 101 bits (243), Expect = 4e-21
Identities = 71/280 (25%), Positives = 124/280 (44%), Gaps = 5/280 (1%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SLD++P+ +L T D ++N GH VT V + P + + +AS
Sbjct: 21 ITSLDLSPNG-KQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASAS 79
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T+R+W + ++H PV + G ++ + S D+ + + L
Sbjct: 80 RDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYS 139
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
+ + + A+F PDG + + +E+ +KIWD + V NF VG + F+ +G
Sbjct: 140 LYRHTHW-VRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSG 198
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLC 454
+A+A D VK+WD+R K + Q+ + + F SG YL A +D +++
Sbjct: 199 TCIASAGSDQTVKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLITASSDGTLKILDL 257
Query: 455 RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ + + HT V F K + AS D + L+
Sbjct: 258 LEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
Score = 87.0 bits (206), Expect = 1e-16
Identities = 62/244 (25%), Positives = 105/244 (43%), Gaps = 8/244 (3%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
KGH +T + P+ + TAS D + +WN H VT + P G+
Sbjct: 15 KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNL 74
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S S D+ + K S+F + + F DG T +E+ +K+W +
Sbjct: 75 LASASRDR---TVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
Q + + H V FS +G + + +ED +K+WD + +A
Sbjct: 132 YRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFA-N 190
Query: 432 ELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDR 489
+ F+ SGT +A AG+D V+V+ R + L+ + H+ + F + YL + S D
Sbjct: 191 FVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDG 250
Query: 490 TLKL 493
TLK+
Sbjct: 251 TLKI 254
Score = 80.6 bits (190), Expect = 1e-14
Identities = 47/203 (23%), Positives = 91/203 (44%), Gaps = 4/203 (1%)
Query: 296 RSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGL 355
+ H +T L L P G + + S D + + + V +T+ QF P G
Sbjct: 15 KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDV-VTSVQFSPHGN 73
Query: 356 IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRK 415
+ + + + V++W ++ + F H PV S+ FS +G +LATA+ED +K+W + +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 416 LKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGV 473
+ F + ++ F G + D ++++ Q + F+D A V
Sbjct: 134 -QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFV 192
Query: 474 RFGKNAQYLASTSMDRTLKLYGI 496
F + +AS D+T+K++ +
Sbjct: 193 DFNPSGTCIASAGSDQTVKVWDV 215
Score = 60.1 bits (139), Expect = 2e-08
Identities = 35/120 (29%), Positives = 64/120 (53%), Gaps = 5/120 (4%)
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR-KLKNFKTIQLEENYAIKELCFDQS 438
F GH +TS+ S NG LATA+ D+ + LW+ + + ++ + ++ + + F
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKD--VVTSVQFSPH 71
Query: 439 GTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
G LA A D VR+++ + + F HTA V F + Q+LA+ S D+++K++ +
Sbjct: 72 GNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
>BC026080-1|AAH26080.1| 478|Homo sapiens WD repeat domain 51B
protein.
Length = 478
Score = 101 bits (243), Expect = 4e-21
Identities = 71/280 (25%), Positives = 124/280 (44%), Gaps = 5/280 (1%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SLD++P+ +L T D ++N GH VT V + P + + +AS
Sbjct: 21 ITSLDLSPNG-KQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASAS 79
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T+R+W + ++H PV + G ++ + S D+ + + L
Sbjct: 80 RDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYS 139
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
+ + + A+F PDG + + +E+ +KIWD + V NF VG + F+ +G
Sbjct: 140 LYRHTHW-VRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSG 198
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLC 454
+A+A D VK+WD+R K + Q+ + + F SG YL A +D +++
Sbjct: 199 TCIASAGSDQTVKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLITASSDGTLKILDL 257
Query: 455 RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ + + HT V F K + AS D + L+
Sbjct: 258 LEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
Score = 87.0 bits (206), Expect = 1e-16
Identities = 62/244 (25%), Positives = 105/244 (43%), Gaps = 8/244 (3%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
KGH +T + P+ + TAS D + +WN H VT + P G+
Sbjct: 15 KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNL 74
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S S D+ + K S+F + + F DG T +E+ +K+W +
Sbjct: 75 LASASRDR---TVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
Q + + H V FS +G + + +ED +K+WD + +A
Sbjct: 132 YRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFA-N 190
Query: 432 ELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDR 489
+ F+ SGT +A AG+D V+V+ R + L+ + H+ + F + YL + S D
Sbjct: 191 FVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDG 250
Query: 490 TLKL 493
TLK+
Sbjct: 251 TLKI 254
Score = 80.6 bits (190), Expect = 1e-14
Identities = 47/203 (23%), Positives = 91/203 (44%), Gaps = 4/203 (1%)
Query: 296 RSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGL 355
+ H +T L L P G + + S D + + + V +T+ QF P G
Sbjct: 15 KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDV-VTSVQFSPHGN 73
Query: 356 IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRK 415
+ + + + V++W ++ + F H PV S+ FS +G +LATA+ED +K+W + +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 416 LKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGV 473
+ F + ++ F G + D ++++ Q + F+D A V
Sbjct: 134 -QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFV 192
Query: 474 RFGKNAQYLASTSMDRTLKLYGI 496
F + +AS D+T+K++ +
Sbjct: 193 DFNPSGTCIASAGSDQTVKVWDV 215
Score = 60.1 bits (139), Expect = 2e-08
Identities = 35/120 (29%), Positives = 64/120 (53%), Gaps = 5/120 (4%)
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR-KLKNFKTIQLEENYAIKELCFDQS 438
F GH +TS+ S NG LATA+ D+ + LW+ + + ++ + ++ + + F
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKD--VVTSVQFSPH 71
Query: 439 GTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
G LA A D VR+++ + + F HTA V F + Q+LA+ S D+++K++ +
Sbjct: 72 GNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
>AK074772-1|BAC11198.1| 478|Homo sapiens protein ( Homo sapiens
cDNA FLJ90291 fis, clone NT2RP1001031, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 478
Score = 101 bits (243), Expect = 4e-21
Identities = 71/280 (25%), Positives = 124/280 (44%), Gaps = 5/280 (1%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SLD++P+ +L T D ++N GH VT V + P + + +AS
Sbjct: 21 ITSLDLSPNG-KQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASAS 79
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK 336
D T+R+W + ++H PV + G ++ + S D+ + + L
Sbjct: 80 RDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYS 139
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
+ + + A+F PDG + + +E+ +KIWD + V NF VG + F+ +G
Sbjct: 140 LYRHTHW-VRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSG 198
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLC 454
+A+A D VK+WD+R K + Q+ + + F SG YL A +D +++
Sbjct: 199 TCIASAGSDQTVKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLITASSDGTLKILDL 257
Query: 455 RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ + + HT V F K + AS D + L+
Sbjct: 258 LEGRLIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 297
Score = 87.0 bits (206), Expect = 1e-16
Identities = 62/244 (25%), Positives = 105/244 (43%), Gaps = 8/244 (3%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
KGH +T + P+ + TAS D + +WN H VT + P G+
Sbjct: 15 KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNL 74
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S S D+ + K S+F + + F DG T +E+ +K+W +
Sbjct: 75 LASASRDR---TVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
Q + + H V FS +G + + +ED +K+WD + +A
Sbjct: 132 YRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFA-N 190
Query: 432 ELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDR 489
+ F+ SGT +A AG+D V+V+ R + L+ + H+ + F + YL + S D
Sbjct: 191 FVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDG 250
Query: 490 TLKL 493
TLK+
Sbjct: 251 TLKI 254
Score = 80.6 bits (190), Expect = 1e-14
Identities = 47/203 (23%), Positives = 91/203 (44%), Gaps = 4/203 (1%)
Query: 296 RSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGL 355
+ H +T L L P G + + S D + + + V +T+ QF P G
Sbjct: 15 KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDV-VTSVQFSPHGN 73
Query: 356 IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRK 415
+ + + + V++W ++ + F H PV S+ FS +G +LATA+ED +K+W + +
Sbjct: 74 LLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYR 133
Query: 416 LKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGV 473
+ F + ++ F G + D ++++ Q + F+D A V
Sbjct: 134 -QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFV 192
Query: 474 RFGKNAQYLASTSMDRTLKLYGI 496
F + +AS D+T+K++ +
Sbjct: 193 DFNPSGTCIASAGSDQTVKVWDV 215
Score = 60.1 bits (139), Expect = 2e-08
Identities = 35/120 (29%), Positives = 64/120 (53%), Gaps = 5/120 (4%)
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR-KLKNFKTIQLEENYAIKELCFDQS 438
F GH +TS+ S NG LATA+ D+ + LW+ + + ++ + ++ + + F
Sbjct: 14 FKGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKD--VVTSVQFSPH 71
Query: 439 GTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
G LA A D VR+++ + + F HTA V F + Q+LA+ S D+++K++ +
Sbjct: 72 GNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSM 131
>CR457279-1|CAG33560.1| 330|Homo sapiens WDR5B protein.
Length = 330
Score = 95.5 bits (227), Expect = 4e-19
Identities = 53/213 (24%), Positives = 106/213 (49%), Gaps = 3/213 (1%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S+L++ +D+ +++ + + + LKGH+ V ++P + +I+ S D T+++W
Sbjct: 93 SDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIW 152
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
V T + L +H PV+ + + +G ++S S D D +GQ L + D
Sbjct: 153 EVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPP 212
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI--SFS-ENGYYLAT 401
++ +F P+G T T ++ +K+WD + + GH I +FS G ++ +
Sbjct: 213 VSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVS 272
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC 434
+ED+ V +W+L+ + + +Q + I C
Sbjct: 273 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC 305
Score = 90.2 bits (214), Expect = 1e-17
Identities = 65/272 (23%), Positives = 122/272 (44%), Gaps = 8/272 (2%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTS 289
L + DR ++ + L GH +++ V + D +++AS D T+++W+V +
Sbjct: 56 LASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSG 115
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
+ L+ H V + +P + ++S S D+ +++TG+ L +S S ++
Sbjct: 116 KCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSD-PVSAVH 174
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG-PVTSISFSENGYYLATAAEDSCV 408
F+ G + +G+ + +IWD + PV+ + FS NG Y+ TA D+ +
Sbjct: 175 FNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTL 234
Query: 409 KLWDLRKLKNFKTI--QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR-QWQEL-KVFN 464
KLWD + + KT E Y I G ++ D VY+ Q +E+ +
Sbjct: 235 KLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 294
Query: 465 DHTASATGVRFGKNAQYLASTSM--DRTLKLY 494
HT +AS ++ D+T+KL+
Sbjct: 295 GHTDVVISAACHPTENLIASAALENDKTIKLW 326
Score = 83.0 bits (196), Expect = 2e-15
Identities = 48/216 (22%), Positives = 104/216 (48%), Gaps = 3/216 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GHT+ V+ V + P+ + + ++S D I +W + L H+ ++ ++
Sbjct: 37 LVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSS 96
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
++S S D+ D+R+G+ L + S + F+P + +G+ + VKIW++K
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNY-VFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ H PV+++ F+ +G + + + D ++WD + KT+ ++N +
Sbjct: 156 TGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSF 215
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
+ F +G Y+ A D ++++ + + LK + H
Sbjct: 216 VKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGH 251
Score = 65.3 bits (152), Expect = 5e-10
Identities = 46/225 (20%), Positives = 101/225 (44%), Gaps = 5/225 (2%)
Query: 273 ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ 332
+++S + + V P L H V+ + P G+++ S+S+D+ G+
Sbjct: 15 LSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGK 74
Query: 333 LLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISF 392
K + ++ + D + +++ +K+WD++ + GH V +F
Sbjct: 75 -YEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNF 133
Query: 393 SENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VR 450
+ + + + D VK+W+++ K KT+ + + + F+ SG+ + D R
Sbjct: 134 NPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSD-PVSAVHFNCSGSLIVSGSYDGLCR 192
Query: 451 VYLCRQWQELK-VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++ Q LK + +D + V+F N +Y+ + ++D TLKL+
Sbjct: 193 IWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLW 237
Score = 32.3 bits (70), Expect = 4.0
Identities = 12/30 (40%), Positives = 21/30 (70%)
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLYG 495
HT + + V+F N ++LAS+S DR + ++G
Sbjct: 40 HTEAVSSVKFSPNGEWLASSSADRLIIIWG 69
>BC043494-1|AAH43494.1| 330|Homo sapiens WD repeat domain 5B
protein.
Length = 330
Score = 95.5 bits (227), Expect = 4e-19
Identities = 53/213 (24%), Positives = 106/213 (49%), Gaps = 3/213 (1%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S+L++ +D+ +++ + + + LKGH+ V ++P + +I+ S D T+++W
Sbjct: 93 SDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIW 152
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
V T + L +H PV+ + + +G ++S S D D +GQ L + D
Sbjct: 153 EVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPP 212
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI--SFS-ENGYYLAT 401
++ +F P+G T T ++ +K+WD + + GH I +FS G ++ +
Sbjct: 213 VSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVS 272
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC 434
+ED+ V +W+L+ + + +Q + I C
Sbjct: 273 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC 305
Score = 90.2 bits (214), Expect = 1e-17
Identities = 65/272 (23%), Positives = 122/272 (44%), Gaps = 8/272 (2%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTS 289
L + DR ++ + L GH +++ V + D +++AS D T+++W+V +
Sbjct: 56 LASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSG 115
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
+ L+ H V + +P + ++S S D+ +++TG+ L +S S ++
Sbjct: 116 KCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSD-PVSAVH 174
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG-PVTSISFSENGYYLATAAEDSCV 408
F+ G + +G+ + +IWD + PV+ + FS NG Y+ TA D+ +
Sbjct: 175 FNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTL 234
Query: 409 KLWDLRKLKNFKTI--QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR-QWQEL-KVFN 464
KLWD + + KT E Y I G ++ D VY+ Q +E+ +
Sbjct: 235 KLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 294
Query: 465 DHTASATGVRFGKNAQYLASTSM--DRTLKLY 494
HT +AS ++ D+T+KL+
Sbjct: 295 GHTDVVISAACHPTENLIASAALENDKTIKLW 326
Score = 83.0 bits (196), Expect = 2e-15
Identities = 48/216 (22%), Positives = 104/216 (48%), Gaps = 3/216 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GHT+ V+ V + P+ + + ++S D I +W + L H+ ++ ++
Sbjct: 37 LVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSS 96
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
++S S D+ D+R+G+ L + S + F+P + +G+ + VKIW++K
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNY-VFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ H PV+++ F+ +G + + + D ++WD + KT+ ++N +
Sbjct: 156 TGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSF 215
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
+ F +G Y+ A D ++++ + + LK + H
Sbjct: 216 VKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGH 251
Score = 65.3 bits (152), Expect = 5e-10
Identities = 46/225 (20%), Positives = 101/225 (44%), Gaps = 5/225 (2%)
Query: 273 ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ 332
+++S + + V P L H V+ + P G+++ S+S+D+ G+
Sbjct: 15 LSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGK 74
Query: 333 LLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISF 392
K + ++ + D + +++ +K+WD++ + GH V +F
Sbjct: 75 -YEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNF 133
Query: 393 SENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VR 450
+ + + + D VK+W+++ K KT+ + + + F+ SG+ + D R
Sbjct: 134 NPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSD-PVSAVHFNCSGSLIVSGSYDGLCR 192
Query: 451 VYLCRQWQELK-VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++ Q LK + +D + V+F N +Y+ + ++D TLKL+
Sbjct: 193 IWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLW 237
Score = 32.3 bits (70), Expect = 4.0
Identities = 12/30 (40%), Positives = 21/30 (70%)
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLYG 495
HT + + V+F N ++LAS+S DR + ++G
Sbjct: 40 HTEAVSSVKFSPNGEWLASSSADRLIIIWG 69
>AK127882-1|BAC87175.1| 369|Homo sapiens protein ( Homo sapiens
cDNA FLJ45988 fis, clone PUAEN2006639, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 369
Score = 95.5 bits (227), Expect = 4e-19
Identities = 66/245 (26%), Positives = 112/245 (45%), Gaps = 4/245 (1%)
Query: 212 ASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH-PDED 270
A + + ++ +N S S +TG DR +++ + + + L+GH V + ++ P D
Sbjct: 90 AHILPLTNVALNKSG-SCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGD 148
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
+ T S D T ++W+V T + R H + LS +P V + S D DI+
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQN 208
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G+ + + S + + F+ G TG+ + V +WD V GH ++S
Sbjct: 209 GEEVYTLRGHSA-EIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSA 267
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVR 450
SF+ + + T + D KLWD K T+ ++ I + CFD +G +A A D
Sbjct: 268 SFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDD-EILDSCFDYTGKLIATASADDG 326
Query: 451 VYLCR 455
V LCR
Sbjct: 327 VSLCR 331
Score = 76.2 bits (179), Expect = 3e-13
Identities = 49/203 (24%), Positives = 94/203 (46%), Gaps = 3/203 (1%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPD 353
+L++H P+T ++L+ +G ++ S D+ D +G+ L + V A +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 354 GLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
G TG+ + K+W ++ F GH + +SF+ +AT + D+ KLWD+
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDI 206
Query: 414 RKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASAT 471
+ + T++ + I L F+ SG + D V V+ +++ + H A +
Sbjct: 207 QNGEEVYTLR-GHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEIS 265
Query: 472 GVRFGKNAQYLASTSMDRTLKLY 494
F + + + SMD+T KL+
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLW 288
Score = 74.5 bits (175), Expect = 8e-13
Identities = 40/162 (24%), Positives = 73/162 (45%), Gaps = 2/162 (1%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSL-HPT 310
+LK H +T V + IT S D T ++W+ + + L H V ++ +P
Sbjct: 87 VLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPY 146
Query: 311 GDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWD 370
GD + + S D+ + TG+ + + F+P + TG+ ++ K+WD
Sbjct: 147 GDKIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDTTAKLWD 205
Query: 371 LKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
++ V GH + S+SF+ +G + T + D V +WD
Sbjct: 206 IQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWD 247
Score = 51.2 bits (117), Expect = 8e-06
Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 4/164 (2%)
Query: 334 LTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
L KV + LT + G F TG+ + K+WD + GH V +I+F+
Sbjct: 84 LFKVLKAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFN 143
Query: 394 E-NGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VR 450
G +AT + D KLW + K + T + I L F+ T +A D +
Sbjct: 144 NPYGDKIATGSFDKTCKLWSVETGKCYHTFR-GHTAEIVCLSFNPQSTLVATGSMDTTAK 202
Query: 451 VYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++ + +E+ H+A + F + + + S D T+ ++
Sbjct: 203 LWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVVVW 246
Score = 46.4 bits (105), Expect = 2e-04
Identities = 28/117 (23%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H+ P+T+++ +++G T + D KLWD + T++ N + G +
Sbjct: 91 HILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGDKI 150
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A D +++ + F HTA + F + +A+ SMD T KL+ I+
Sbjct: 151 ATGSFDKTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQ 207
>BX649632-1|CAI18774.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 93.5 bits (222), Expect = 2e-18
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 3/213 (1%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD + L++ +D+ +++ + + + LKGH+ V ++P + +++ S D ++R+W
Sbjct: 97 SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+V T + L +H PV+ + + G ++S+S D D +GQ L + D
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI--SFS-ENGYYLAT 401
++ +F P+G T ++ +K+WD + + + GH I +FS G ++ +
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC 434
+ED+ V +W+L+ + + +Q + I C
Sbjct: 277 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISTAC 309
Score = 89.8 bits (213), Expect = 2e-17
Identities = 48/216 (22%), Positives = 106/216 (49%), Gaps = 3/216 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GHTK V+ V + P+ + + ++S D I++W + + H ++ ++ +
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
++S S D+ D+ +G+ L + S + F+P + +G+ + V+IWD+K
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNY-VFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ P H PV+++ F+ +G + +++ D ++WD + KT+ ++N +
Sbjct: 160 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 219
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
+ F +G Y+ A D ++++ + + LK + H
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 255
Score = 70.5 bits (165), Expect = 1e-11
Identities = 46/206 (22%), Positives = 96/206 (46%), Gaps = 11/206 (5%)
Query: 295 LRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG 354
L H V+ + P G+++ S+S+D+ G+ +S + ++ + D
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHK-LGISDVAWSSDS 99
Query: 355 LIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ + +++ +KIWD+ + GH V +F+ + + + D V++WD++
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 415 KLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQW-----QELK-VFNDHTA 468
K KT+ + + + F++ G+ + + D LCR W Q LK + +D
Sbjct: 160 TGKCLKTLPAHSD-PVSAVHFNRDGSLIVSSSYDG---LCRIWDTASGQCLKTLIDDDNP 215
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLY 494
+ V+F N +Y+ + ++D TLKL+
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLW 241
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/200 (24%), Positives = 89/200 (44%), Gaps = 6/200 (3%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + NP + +++G D + +++ T + + L H+ V+ V ++ D ++++S
Sbjct: 132 VFCCNFNPQSNL-IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGP-VTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
D R+W+ + Q L D P V+ + P G Y+L+ + D D G+ L
Sbjct: 191 YDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLK 250
Query: 336 KVSDFSGVSLTT-AQFH-PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
+ A F G +G+E++ V IW+L+ + V GH V S +
Sbjct: 251 TYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACH 310
Query: 394 ENGYYLATAA--EDSCVKLW 411
+A+AA D +KLW
Sbjct: 311 PTENIIASAALENDKTIKLW 330
Score = 34.3 bits (75), Expect = 1.0
Identities = 12/30 (40%), Positives = 22/30 (73%)
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLYG 495
HT + + V+F N ++LAS+S D+ +K++G
Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADKLIKIWG 73
Score = 31.1 bits (67), Expect = 9.3
Identities = 16/70 (22%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 429 AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTS 486
A+ + F +G +LA + D ++++ + K + H + V + ++ L S S
Sbjct: 47 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 106
Query: 487 MDRTLKLYGI 496
D+TLK++ +
Sbjct: 107 DDKTLKIWDV 116
>BC001635-1|AAH01635.1| 334|Homo sapiens WD repeat domain 5
protein.
Length = 334
Score = 93.5 bits (222), Expect = 2e-18
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 3/213 (1%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD + L++ +D+ +++ + + + LKGH+ V ++P + +++ S D ++R+W
Sbjct: 97 SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+V T + L +H PV+ + + G ++S+S D D +GQ L + D
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI--SFS-ENGYYLAT 401
++ +F P+G T ++ +K+WD + + + GH I +FS G ++ +
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC 434
+ED+ V +W+L+ + + +Q + I C
Sbjct: 277 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISTAC 309
Score = 89.8 bits (213), Expect = 2e-17
Identities = 48/216 (22%), Positives = 106/216 (49%), Gaps = 3/216 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GHTK V+ V + P+ + + ++S D I++W + + H ++ ++ +
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
++S S D+ D+ +G+ L + S + F+P + +G+ + V+IWD+K
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNY-VFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ P H PV+++ F+ +G + +++ D ++WD + KT+ ++N +
Sbjct: 160 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 219
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
+ F +G Y+ A D ++++ + + LK + H
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 255
Score = 70.5 bits (165), Expect = 1e-11
Identities = 46/206 (22%), Positives = 96/206 (46%), Gaps = 11/206 (5%)
Query: 295 LRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG 354
L H V+ + P G+++ S+S+D+ G+ +S + ++ + D
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHK-LGISDVAWSSDS 99
Query: 355 LIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ + +++ +KIWD+ + GH V +F+ + + + D V++WD++
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 415 KLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQW-----QELK-VFNDHTA 468
K KT+ + + + F++ G+ + + D LCR W Q LK + +D
Sbjct: 160 TGKCLKTLPAHSD-PVSAVHFNRDGSLIVSSSYDG---LCRIWDTASGQCLKTLIDDDNP 215
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLY 494
+ V+F N +Y+ + ++D TLKL+
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLW 241
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/200 (24%), Positives = 89/200 (44%), Gaps = 6/200 (3%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + NP + +++G D + +++ T + + L H+ V+ V ++ D ++++S
Sbjct: 132 VFCCNFNPQSNL-IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGP-VTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
D R+W+ + Q L D P V+ + P G Y+L+ + D D G+ L
Sbjct: 191 YDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLK 250
Query: 336 KVSDFSGVSLTT-AQFH-PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
+ A F G +G+E++ V IW+L+ + V GH V S +
Sbjct: 251 TYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACH 310
Query: 394 ENGYYLATAA--EDSCVKLW 411
+A+AA D +KLW
Sbjct: 311 PTENIIASAALENDKTIKLW 330
Score = 34.3 bits (75), Expect = 1.0
Identities = 12/30 (40%), Positives = 22/30 (73%)
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLYG 495
HT + + V+F N ++LAS+S D+ +K++G
Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADKLIKIWG 73
Score = 31.1 bits (67), Expect = 9.3
Identities = 16/70 (22%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 429 AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTS 486
A+ + F +G +LA + D ++++ + K + H + V + ++ L S S
Sbjct: 47 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 106
Query: 487 MDRTLKLYGI 496
D+TLK++ +
Sbjct: 107 DDKTLKIWDV 116
>AK000552-1|BAA91248.1| 334|Homo sapiens protein ( Homo sapiens
cDNA FLJ20545 fis, clone KAT11476. ).
Length = 334
Score = 93.5 bits (222), Expect = 2e-18
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 3/213 (1%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD + L++ +D+ +++ + + + LKGH+ V ++P + +++ S D ++R+W
Sbjct: 97 SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 156
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+V T + L +H PV+ + + G ++S+S D D +GQ L + D
Sbjct: 157 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 216
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI--SFS-ENGYYLAT 401
++ +F P+G T ++ +K+WD + + + GH I +FS G ++ +
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 276
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC 434
+ED+ V +W+L+ + + +Q + I C
Sbjct: 277 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISTAC 309
Score = 89.8 bits (213), Expect = 2e-17
Identities = 48/216 (22%), Positives = 106/216 (49%), Gaps = 3/216 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GHTK V+ V + P+ + + ++S D I++W + + H ++ ++ +
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 100
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
++S S D+ D+ +G+ L + S + F+P + +G+ + V+IWD+K
Sbjct: 101 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNY-VFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ P H PV+++ F+ +G + +++ D ++WD + KT+ ++N +
Sbjct: 160 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 219
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
+ F +G Y+ A D ++++ + + LK + H
Sbjct: 220 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 255
Score = 70.5 bits (165), Expect = 1e-11
Identities = 46/206 (22%), Positives = 96/206 (46%), Gaps = 11/206 (5%)
Query: 295 LRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG 354
L H V+ + P G+++ S+S+D+ G+ +S + ++ + D
Sbjct: 41 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHK-LGISDVAWSSDS 99
Query: 355 LIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ + +++ +KIWD+ + GH V +F+ + + + D V++WD++
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 159
Query: 415 KLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQW-----QELK-VFNDHTA 468
K KT+ + + + F++ G+ + + D LCR W Q LK + +D
Sbjct: 160 TGKCLKTLPAHSD-PVSAVHFNRDGSLIVSSSYDG---LCRIWDTASGQCLKTLIDDDNP 215
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLY 494
+ V+F N +Y+ + ++D TLKL+
Sbjct: 216 PVSFVKFSPNGKYILAATLDNTLKLW 241
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/200 (24%), Positives = 89/200 (44%), Gaps = 6/200 (3%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + NP + +++G D + +++ T + + L H+ V+ V ++ D ++++S
Sbjct: 132 VFCCNFNPQSNL-IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 190
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGP-VTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
D R+W+ + Q L D P V+ + P G Y+L+ + D D G+ L
Sbjct: 191 YDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLK 250
Query: 336 KVSDFSGVSLTT-AQFH-PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
+ A F G +G+E++ V IW+L+ + V GH V S +
Sbjct: 251 TYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACH 310
Query: 394 ENGYYLATAA--EDSCVKLW 411
+A+AA D +KLW
Sbjct: 311 PTENIIASAALENDKTIKLW 330
Score = 34.3 bits (75), Expect = 1.0
Identities = 12/30 (40%), Positives = 22/30 (73%)
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLYG 495
HT + + V+F N ++LAS+S D+ +K++G
Sbjct: 44 HTKAVSSVKFSPNGEWLASSSADKLIKIWG 73
Score = 31.1 bits (67), Expect = 9.3
Identities = 16/70 (22%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 429 AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTS 486
A+ + F +G +LA + D ++++ + K + H + V + ++ L S S
Sbjct: 47 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 106
Query: 487 MDRTLKLYGI 496
D+TLK++ +
Sbjct: 107 DDKTLKIWDV 116
>AJ011376-1|CAB66159.1| 362|Homo sapiens hypothetical protein
protein.
Length = 362
Score = 93.5 bits (222), Expect = 2e-18
Identities = 50/213 (23%), Positives = 106/213 (49%), Gaps = 3/213 (1%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD + L++ +D+ +++ + + + LKGH+ V ++P + +++ S D ++R+W
Sbjct: 125 SDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIW 184
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+V T + L +H PV+ + + G ++S+S D D +GQ L + D
Sbjct: 185 DVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPP 244
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI--SFS-ENGYYLAT 401
++ +F P+G T ++ +K+WD + + + GH I +FS G ++ +
Sbjct: 245 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVS 304
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC 434
+ED+ V +W+L+ + + +Q + I C
Sbjct: 305 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISTAC 337
Score = 89.8 bits (213), Expect = 2e-17
Identities = 48/216 (22%), Positives = 106/216 (49%), Gaps = 3/216 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GHTK V+ V + P+ + + ++S D I++W + + H ++ ++ +
Sbjct: 69 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSN 128
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
++S S D+ D+ +G+ L + S + F+P + +G+ + V+IWD+K
Sbjct: 129 LLVSASDDKTLKIWDVSSGKCLKTLKGHSNY-VFCCNFNPQSNLIVSGSFDESVRIWDVK 187
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ P H PV+++ F+ +G + +++ D ++WD + KT+ ++N +
Sbjct: 188 TGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSF 247
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDH 466
+ F +G Y+ A D ++++ + + LK + H
Sbjct: 248 VKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGH 283
Score = 70.5 bits (165), Expect = 1e-11
Identities = 46/206 (22%), Positives = 96/206 (46%), Gaps = 11/206 (5%)
Query: 295 LRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG 354
L H V+ + P G+++ S+S+D+ G+ +S + ++ + D
Sbjct: 69 LAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHK-LGISDVAWSSDS 127
Query: 355 LIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ + +++ +KIWD+ + GH V +F+ + + + D V++WD++
Sbjct: 128 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVK 187
Query: 415 KLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQW-----QELK-VFNDHTA 468
K KT+ + + + F++ G+ + + D LCR W Q LK + +D
Sbjct: 188 TGKCLKTLPAHSD-PVSAVHFNRDGSLIVSSSYDG---LCRIWDTASGQCLKTLIDDDNP 243
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLY 494
+ V+F N +Y+ + ++D TLKL+
Sbjct: 244 PVSFVKFSPNGKYILAATLDNTLKLW 269
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/200 (24%), Positives = 89/200 (44%), Gaps = 6/200 (3%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ + NP + +++G D + +++ T + + L H+ V+ V ++ D ++++S
Sbjct: 160 VFCCNFNPQSNL-IVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSS 218
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGP-VTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
D R+W+ + Q L D P V+ + P G Y+L+ + D D G+ L
Sbjct: 219 YDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLK 278
Query: 336 KVSDFSGVSLTT-AQFH-PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
+ A F G +G+E++ V IW+L+ + V GH V S +
Sbjct: 279 TYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACH 338
Query: 394 ENGYYLATAA--EDSCVKLW 411
+A+AA D +KLW
Sbjct: 339 PTENIIASAALENDKTIKLW 358
Score = 34.3 bits (75), Expect = 1.0
Identities = 12/30 (40%), Positives = 22/30 (73%)
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLYG 495
HT + + V+F N ++LAS+S D+ +K++G
Sbjct: 72 HTKAVSSVKFSPNGEWLASSSADKLIKIWG 101
Score = 31.1 bits (67), Expect = 9.3
Identities = 16/70 (22%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 429 AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTS 486
A+ + F +G +LA + D ++++ + K + H + V + ++ L S S
Sbjct: 75 AVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSAS 134
Query: 487 MDRTLKLYGI 496
D+TLK++ +
Sbjct: 135 DDKTLKIWDV 144
>AK002149-1|BAA92110.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
Length = 330
Score = 92.3 bits (219), Expect = 4e-18
Identities = 66/272 (24%), Positives = 123/272 (45%), Gaps = 8/272 (2%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTS 289
L + DR ++ + L GH +++ V + D +++AS D T+++W+V +
Sbjct: 56 LASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSG 115
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
+ L+ H V + +P + ++S S D+ +++TG+ L +S S ++
Sbjct: 116 KCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSD-PVSAVH 174
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG-PVTSISFSENGYYLATAAEDSCV 408
F+ G + +G+ + +IWD + PV+ + FS NG Y+ TA D+ +
Sbjct: 175 FNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTL 234
Query: 409 KLWDLRKLKNFKTI--QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR-QWQEL-KVFN 464
KLWD + + KT Q E Y I G ++ D VY+ Q +E+ +
Sbjct: 235 KLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQ 294
Query: 465 DHTASATGVRFGKNAQYLASTSM--DRTLKLY 494
HT +AS ++ D+T+KL+
Sbjct: 295 GHTDVVISAACHPTENLIASAALENDKTIKLW 326
Score = 92.3 bits (219), Expect = 4e-18
Identities = 52/213 (24%), Positives = 105/213 (49%), Gaps = 3/213 (1%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD S+L++ +D+ +++ + + + LKGH+ V ++P + +I+ S D T+++W
Sbjct: 93 SDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIW 152
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
V T + L +H PV+ + + +G ++S S D D +GQ L + D
Sbjct: 153 EVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPP 212
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI--SFS-ENGYYLAT 401
++ +F P+G T T ++ +K+WD + + G I +FS G ++ +
Sbjct: 213 VSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVS 272
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELC 434
+ED+ V +W+L+ + + +Q + I C
Sbjct: 273 GSEDNLVYIWNLQTKEIVQKLQGHTDVVISAAC 305
Score = 82.6 bits (195), Expect = 3e-15
Identities = 45/196 (22%), Positives = 94/196 (47%), Gaps = 1/196 (0%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GHT+ V+ V + P+ + + ++S D I +W + L H+ ++ ++
Sbjct: 37 LVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSS 96
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
++S S D+ D+R+G+ L + S + F+P + +G+ + VKIW++K
Sbjct: 97 RLVSASDDKTLKLWDVRSGKCLKTLKGHSNY-VFCCNFNPPSNLIISGSFDETVKIWEVK 155
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ H PV+++ F+ +G + + + D ++WD + KT+ ++N +
Sbjct: 156 TGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSF 215
Query: 433 LCFDQSGTYLAIAGTD 448
+ F +G Y+ A D
Sbjct: 216 VKFSPNGKYILTATLD 231
Score = 65.3 bits (152), Expect = 5e-10
Identities = 46/225 (20%), Positives = 101/225 (44%), Gaps = 5/225 (2%)
Query: 273 ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ 332
+++S + + V P L H V+ + P G+++ S+S+D+ G+
Sbjct: 15 LSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGK 74
Query: 333 LLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISF 392
K + ++ + D + +++ +K+WD++ + GH V +F
Sbjct: 75 -YEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNF 133
Query: 393 SENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VR 450
+ + + + D VK+W+++ K KT+ + + + F+ SG+ + D R
Sbjct: 134 NPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSD-PVSAVHFNCSGSLIVSGSYDGLCR 192
Query: 451 VYLCRQWQELK-VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++ Q LK + +D + V+F N +Y+ + ++D TLKL+
Sbjct: 193 IWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLW 237
Score = 32.3 bits (70), Expect = 4.0
Identities = 12/30 (40%), Positives = 21/30 (70%)
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLYG 495
HT + + V+F N ++LAS+S DR + ++G
Sbjct: 40 HTEAVSSVKFSPNGEWLASSSADRLIIIWG 69
>BC127949-1|AAI27950.1| 314|Homo sapiens similar to hypothetical
protein FLJ25955 protein.
Length = 314
Score = 90.6 bits (215), Expect = 1e-17
Identities = 71/271 (26%), Positives = 125/271 (46%), Gaps = 10/271 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D LLTG D + + Q++ L GHT V + PD +AS D T+R+W+
Sbjct: 32 DGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVRLWD 91
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V ++ +L+ H V +S P + S D+ D+++GQ+L + S+
Sbjct: 92 VARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRD-SI 150
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN---FPGHVGPVTSISFSENGYYLATA 402
++ F P TG+ +S V+IWDL+ + + GH G ++ + +S +G LA+
Sbjct: 151 QSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCLCYSASG-LLASG 209
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENYA-IKELCFDQSGTYLAIAGTD--VRVYLCRQWQE 459
+ D + +W + + IQL+ + +K + F +LA AG V+V+ C +
Sbjct: 210 SWDKTIHIW--KPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKC 267
Query: 460 LKVFNDHTASATGVRFGKNAQYLASTSMDRT 490
L+ A F + + L S + D+T
Sbjct: 268 LETLKGVLDVAHTCAFTPDGKILVSGAADQT 298
Score = 83.8 bits (198), Expect = 1e-15
Identities = 64/243 (26%), Positives = 100/243 (41%), Gaps = 6/243 (2%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H +V + PD ++T S D + W + Q L H GPV P G
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
S S D D+ + L +V S+ T F PD +G + +V +WD++
Sbjct: 80 SASCDCTVRLWDVARAKCL-RVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQ 138
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA--IKEL 433
+ GH + S FS LAT + DS V++WDLR + + Q E ++ I L
Sbjct: 139 MLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHSGNISCL 198
Query: 434 CFDQSGTYLAIAGTDVRVYLCRQWQE--LKVFNDHTASATGVRFGKNAQYLASTSMDRTL 491
C+ SG LA D +++ + L H + F + +LAS R +
Sbjct: 199 CYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMV 257
Query: 492 KLY 494
K++
Sbjct: 258 KVW 260
Score = 74.5 bits (175), Expect = 8e-13
Identities = 44/157 (28%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + ++ F PDG + TG+E+ V W+ + + GH GPV FS +G+ A+
Sbjct: 21 GGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFAS 80
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYL--CRQWQE 459
A+ D V+LWD+ + K + ++ + +++ + F LA G D RV L + Q
Sbjct: 81 ASCDCTVRLWDVARAKCLRVLKGHQR-SVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 460 LKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
L++ H S F LA+ S D T++++ +
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVRIWDL 176
Score = 48.4 bits (110), Expect = 6e-05
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSG 439
F H G V S +FS +G L T +ED CV W+ R + + +K F G
Sbjct: 17 FGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLG-GHTGPVKFCRFSPDG 75
Query: 440 TYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A A D VR++ + + L+V H S V F +++ LAS D+ + L+ ++
Sbjct: 76 HLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQ 135
>AF490390-1|AAM97147.1| 631|Homo sapiens sperm-associated WD repeat
protein protein.
Length = 631
Score = 89.4 bits (212), Expect = 3e-17
Identities = 67/266 (25%), Positives = 114/266 (42%), Gaps = 3/266 (1%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTS 289
L++ G DR V V+ GHT ++ +HP D + T+S D T+++W++ T
Sbjct: 367 LVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTG 426
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
H V + H G++V S+S D+ D+ + + + + S+ + +
Sbjct: 427 DCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTD-SVNSIE 485
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
F P T + + + IWD + + GH+ + F G+ +A+ K
Sbjct: 486 FFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTK 545
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA-GTDVRVYLCRQWQELKVFNDHTA 468
LWD RKL +I + + E+ FD SG LA A G V L + E+ H
Sbjct: 546 LWDFRKLLPIVSIDIGPSPG-NEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHEN 604
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLY 494
A V F + + L S D T++ +
Sbjct: 605 EAHTVVFSHDGEILFSGGSDGTVRTW 630
Score = 74.9 bits (176), Expect = 6e-13
Identities = 53/221 (23%), Positives = 100/221 (45%), Gaps = 5/221 (2%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
KL T D +++ T + +GH++ V +H + V ++S D T ++W+V +
Sbjct: 408 KLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS 467
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-SLTT 347
+ L H V + P + +L++S+D+ + D RTG + + S + + S+
Sbjct: 468 ERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTG--ICEQSLYGHMHSIND 525
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
A F P G + + K+WD ++ + + P ++F +G LA A+ +
Sbjct: 526 AIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGV 585
Query: 408 VKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+ L DL+ + K + EN A + F G L G+D
Sbjct: 586 IHLLDLKSGEIHK-LMGHENEA-HTVVFSHDGEILFSGGSD 624
Score = 60.5 bits (140), Expect = 1e-08
Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 1/163 (0%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
I + H V+ V P +D +++ D +V +P H ++ HP+G
Sbjct: 347 IFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSG 406
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
D + ++S D D+ TG + S ++ + +H G + + + KIWD+
Sbjct: 407 DKLATSSGDTTVKLWDLCTGDCILTFEGHSR-AVWSCTWHSCGNFVASSSLDKTSKIWDV 465
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ GH V SI F L T++ D + +WD R
Sbjct: 466 NSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDAR 508
>AF310672-1|AAM63956.1| 631|Homo sapiens PF20 variant 1a protein.
Length = 631
Score = 89.4 bits (212), Expect = 3e-17
Identities = 67/266 (25%), Positives = 114/266 (42%), Gaps = 3/266 (1%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTS 289
L++ G DR V V+ GHT ++ +HP D + T+S D T+++W++ T
Sbjct: 367 LVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCTG 426
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
H V + H G++V S+S D+ D+ + + + + S+ + +
Sbjct: 427 DCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTD-SVNSIE 485
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
F P T + + + IWD + + GH+ + F G+ +A+ K
Sbjct: 486 FFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTK 545
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA-GTDVRVYLCRQWQELKVFNDHTA 468
LWD RKL +I + + E+ FD SG LA A G V L + E+ H
Sbjct: 546 LWDFRKLLPIVSIDIGPSPG-NEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHEN 604
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLY 494
A V F + + L S D T++ +
Sbjct: 605 EAHTVVFSHDGEILFSGGSDGTVRTW 630
Score = 74.9 bits (176), Expect = 6e-13
Identities = 53/221 (23%), Positives = 100/221 (45%), Gaps = 5/221 (2%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
KL T D +++ T + +GH++ V +H + V ++S D T ++W+V +
Sbjct: 408 KLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS 467
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-SLTT 347
+ L H V + P + +L++S+D+ + D RTG + + S + + S+
Sbjct: 468 ERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTG--ICEQSLYGHMHSIND 525
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
A F P G + + K+WD ++ + + P ++F +G LA A+ +
Sbjct: 526 AIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGV 585
Query: 408 VKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+ L DL+ + K + EN A + F G L G+D
Sbjct: 586 IHLLDLKSGEIHK-LMGHENEA-HTVVFSHDGEILFSGGSD 624
Score = 60.5 bits (140), Expect = 1e-08
Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 1/163 (0%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
I + H V+ V P +D +++ D +V +P H ++ HP+G
Sbjct: 347 IFRLHELPVSCVSMQPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSG 406
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
D + ++S D D+ TG + S ++ + +H G + + + KIWD+
Sbjct: 407 DKLATSSGDTTVKLWDLCTGDCILTFEGHSR-AVWSCTWHSCGNFVASSSLDKTSKIWDV 465
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ GH V SI F L T++ D + +WD R
Sbjct: 466 NSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDAR 508
>BC025379-1|AAH25379.1| 571|Homo sapiens SPAG16 protein protein.
Length = 571
Score = 87.0 bits (206), Expect = 1e-16
Identities = 66/266 (24%), Positives = 113/266 (42%), Gaps = 3/266 (1%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTS 289
L++ G DR V V+ GHT ++ +HP D + T+S D T+++W++
Sbjct: 307 LVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSGDTTVKLWDLCKG 366
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
H V + H G++V S+S D+ D+ + + + + S+ + +
Sbjct: 367 DCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTD-SVNSIE 425
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
F P T + + + IWD + + GH+ + F G+ +A+ K
Sbjct: 426 FFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTK 485
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA-GTDVRVYLCRQWQELKVFNDHTA 468
LWD RKL +I + + E+ FD SG LA A G V L + E+ H
Sbjct: 486 LWDFRKLLPIVSIDIGPSPG-NEVNFDSSGRVLAQASGNGVIHLLDLKSGEIHKLMGHEN 544
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLY 494
A V F + + L S D T++ +
Sbjct: 545 EAHTVVFSHDGEILFSGGSDGTVRTW 570
Score = 72.5 bits (170), Expect = 3e-12
Identities = 52/221 (23%), Positives = 99/221 (44%), Gaps = 5/221 (2%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
KL T D +++ + +GH++ V +H + V ++S D T ++W+V +
Sbjct: 348 KLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNS 407
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-SLTT 347
+ L H V + P + +L++S+D+ + D RTG + + S + + S+
Sbjct: 408 ERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTG--ICEQSLYGHMHSIND 465
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
A F P G + + K+WD ++ + + P ++F +G LA A+ +
Sbjct: 466 AIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPGNEVNFDSSGRVLAQASGNGV 525
Query: 408 VKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+ L DL+ + K + EN A + F G L G+D
Sbjct: 526 IHLLDLKSGEIHK-LMGHENEA-HTVVFSHDGEILFSGGSD 564
Score = 65.3 bits (152), Expect = 5e-10
Identities = 36/121 (29%), Positives = 63/121 (52%), Gaps = 3/121 (2%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS-LTTAQFHP 352
I R H+ PV+ +S+HP D ++S D+ W + +L ++ F L+ FHP
Sbjct: 287 IFRLHELPVSCVSMHPHKDILVSCGEDRLWKVLGLPKCNVL--LTGFGHTDWLSDCCFHP 344
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
G T + ++ VK+WDL + + F GH V S ++ G ++A+++ D K+WD
Sbjct: 345 SGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWD 404
Query: 413 L 413
+
Sbjct: 405 V 405
Score = 61.3 bits (142), Expect = 8e-09
Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 1/163 (0%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
I + H V+ V HP +D +++ D +V +P H ++ HP+G
Sbjct: 287 IFRLHELPVSCVSMHPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSG 346
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
D + ++S D D+ G + S ++ + +H G + + + KIWD+
Sbjct: 347 DKLATSSGDTTVKLWDLCKGDCILTFEGHSR-AVWSCTWHSCGNFVASSSLDKTSKIWDV 405
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ GH V SI F L T++ D + +WD R
Sbjct: 406 NSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDAR 448
Score = 41.5 bits (93), Expect = 0.007
Identities = 35/152 (23%), Positives = 67/152 (44%), Gaps = 3/152 (1%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
++ HP I + E+ K+ L + + + GH ++ F +G LAT++
Sbjct: 295 VSCVSMHPHKDILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDKLATSSG 354
Query: 405 DSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKV 462
D+ VKLWDL K T + + A+ + G ++A + D +++ +
Sbjct: 355 DTTVKLWDLCKGDCILTFE-GHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCT 413
Query: 463 FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
HT S + F + L ++S D+TL ++
Sbjct: 414 LYGHTDSVNSIEFFPFSNTLLTSSADKTLSIW 445
>AL354928-6|CAI39637.1| 314|Homo sapiens WD repeat domain 38
protein.
Length = 314
Score = 87.0 bits (206), Expect = 1e-16
Identities = 70/271 (25%), Positives = 123/271 (45%), Gaps = 10/271 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D LLTG D + + Q++ L GHT V + PD +AS D T+R+W+
Sbjct: 32 DGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTVRLWD 91
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V ++ +L+ H V +S P + S D+ D+++GQ+L + S+
Sbjct: 92 VARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHRD-SI 150
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN---FPGHVGPVTSISFSENGYYLATA 402
++ F P TG+ +S V IWDL+ + + GH ++ + +S +G LA+
Sbjct: 151 QSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSASG-LLASG 209
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENYA-IKELCFDQSGTYLAIAGTD--VRVYLCRQWQE 459
+ D + +W + + IQL+ + +K + F +LA AG V+V+ C +
Sbjct: 210 SWDKTIHIW--KPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWDCNTGKC 267
Query: 460 LKVFNDHTASATGVRFGKNAQYLASTSMDRT 490
L+ A F + + L S + D+T
Sbjct: 268 LETLKGVLDVAHTCAFTPDGKILVSGAADQT 298
Score = 82.6 bits (195), Expect = 3e-15
Identities = 64/243 (26%), Positives = 99/243 (40%), Gaps = 6/243 (2%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H +V + PD ++T S D + W + Q L H GPV P G
Sbjct: 20 HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
S S D D+ + L +V S+ T F PD +G + +V +WD++
Sbjct: 80 SASCDCTVRLWDVARAKCL-RVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQ 138
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA--IKEL 433
+ GH + S FS LAT + DS V +WDLR + + Q E ++ I L
Sbjct: 139 MLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCL 198
Query: 434 CFDQSGTYLAIAGTDVRVYLCRQWQE--LKVFNDHTASATGVRFGKNAQYLASTSMDRTL 491
C+ SG LA D +++ + L H + F + +LAS R +
Sbjct: 199 CYSASG-LLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMV 257
Query: 492 KLY 494
K++
Sbjct: 258 KVW 260
Score = 73.3 bits (172), Expect = 2e-12
Identities = 44/157 (28%), Positives = 76/157 (48%), Gaps = 3/157 (1%)
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + ++ F PDG + TG+E+ V W+ + + GH GPV FS +G+ A+
Sbjct: 21 GGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFAS 80
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYL--CRQWQE 459
A+ D V+LWD+ + K + ++ + +++ + F LA G D RV L + Q
Sbjct: 81 ASCDCTVRLWDVARAKCLRVLKGHQR-SVETVSFSPDSRQLASGGWDKRVMLWDVQSGQM 139
Query: 460 LKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
L++ H S F LA+ S D T+ ++ +
Sbjct: 140 LRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIWDL 176
Score = 48.4 bits (110), Expect = 6e-05
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 3/120 (2%)
Query: 380 FPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSG 439
F H G V S +FS +G L T +ED CV W+ R + + +K F G
Sbjct: 17 FGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLG-GHTGPVKFCRFSPDG 75
Query: 440 TYLAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
A A D VR++ + + L+V H S V F +++ LAS D+ + L+ ++
Sbjct: 76 HLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQ 135
>U72342-1|AAC51111.1| 410|Homo sapiens platelet activating factor
acetylhydrolase, brain isoform, 45 kDa subunit protein.
Length = 410
Score = 86.6 bits (205), Expect = 2e-16
Identities = 65/291 (22%), Positives = 130/291 (44%), Gaps = 28/291 (9%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S +++ D V++ +T LKGHT V + + + + S D TI++W+
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
+ + HD V+ +++ P GD+++S S D+ +++TG V F+G
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYC---VKTFTGHREWV 237
Query: 348 AQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS-ENGY------- 397
P DG + + + + V++W + + A H V IS++ E+ Y
Sbjct: 238 RMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEAT 297
Query: 398 ------------YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+L + + D +K+WD+ T+ +N+ ++ + F G ++
Sbjct: 298 GSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW-VRGVLFHSGGKFILSC 356
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
D +RV+ + + +K N H T + F K A Y+ + S+D+T+K++
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 77.8 bits (183), Expect = 8e-14
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 2/193 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GH VTRVI+HP +++AS D TI+VW+ T L+ H V +S +G
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
+ S S+D D + + + + ++++ P+G + + + +K+W+++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDH-NVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
V F GH V + +++G +A+ + D V++W + K K E + ++
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-VVATKECKAELREHEHVVEC 281
Query: 433 LCFDQSGTYLAIA 445
+ + +Y +I+
Sbjct: 282 ISWAPESSYSSIS 294
Score = 74.9 bits (176), Expect = 6e-13
Identities = 58/253 (22%), Positives = 110/253 (43%), Gaps = 24/253 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTE--QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
DHS L + T+ D + + + + GH V+ V P+ D +++AS D TI++
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKM 218
Query: 284 WNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFS------DIRTGQLL 334
W V T H V + + G + S S+DQ W + ++R + +
Sbjct: 219 WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV 278
Query: 335 TKV------SDFSGVSLTTA----QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
+ S +S +S T + G +G+ + +K+WD+ + GH
Sbjct: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 338
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V + F G ++ + A+D +++WD + + KT+ E++ + L F ++ Y+
Sbjct: 339 NWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVT 397
Query: 445 AGTD--VRVYLCR 455
D V+V+ CR
Sbjct: 398 GSVDQTVKVWECR 410
Score = 66.1 bits (154), Expect = 3e-10
Identities = 36/152 (23%), Positives = 74/152 (48%), Gaps = 3/152 (1%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T FHP + + +E++ +K+WD + GH V ISF +G LA+ +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
Query: 405 DSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKV 462
D +KLWD + + +T+ ++ + + +G ++ A D ++++ + +K
Sbjct: 171 DMTIKLWDFQGFECIRTMH-GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229
Query: 463 FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
F H VR ++ +AS S D+T++++
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 26/234 (11%)
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+P L H PVT + HP ++S S D D TG + + S+
Sbjct: 95 IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD-SV 153
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
F G + + + + +K+WD + + GH V+S++ NG ++ +A+ D
Sbjct: 154 QDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 213
Query: 406 SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL---------- 453
+K+W+++ KT + ++ + +Q GT +A D VRV++
Sbjct: 214 KTIKMWEVQTGYCVKTFTGHREW-VRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
Query: 454 --------CRQWQELKVFNDHTASATG---VRFGKNAQYLASTSMDRTLKLYGI 496
C W ++ + ATG + GK +L S S D+T+K++ +
Sbjct: 273 REHEHVVECISWAPESSYSS-ISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
>L13386-1|AAA02881.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 86.6 bits (205), Expect = 2e-16
Identities = 65/291 (22%), Positives = 130/291 (44%), Gaps = 28/291 (9%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S +++ D V++ +T LKGHT V + + + + S D TI++W+
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
+ + HD V+ +++ P GD+++S S D+ +++TG V F+G
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYC---VKTFTGHREWV 237
Query: 348 AQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS-ENGY------- 397
P DG + + + + V++W + + A H V IS++ E+ Y
Sbjct: 238 RMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEAT 297
Query: 398 ------------YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+L + + D +K+WD+ T+ +N+ ++ + F G ++
Sbjct: 298 GSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW-VRGVLFHSGGKFILSC 356
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
D +RV+ + + +K N H T + F K A Y+ + S+D+T+K++
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 77.8 bits (183), Expect = 8e-14
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 2/193 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GH VTRVI+HP +++AS D TI+VW+ T L+ H V +S +G
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
+ S S+D D + + + + ++++ P+G + + + +K+W+++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDH-NVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
V F GH V + +++G +A+ + D V++W + K K E + ++
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-VVATKECKAELREHEHVVEC 281
Query: 433 LCFDQSGTYLAIA 445
+ + +Y +I+
Sbjct: 282 ISWAPESSYSSIS 294
Score = 74.9 bits (176), Expect = 6e-13
Identities = 58/253 (22%), Positives = 110/253 (43%), Gaps = 24/253 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTE--QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
DHS L + T+ D + + + + GH V+ V P+ D +++AS D TI++
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKM 218
Query: 284 WNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFS------DIRTGQLL 334
W V T H V + + G + S S+DQ W + ++R + +
Sbjct: 219 WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV 278
Query: 335 TKV------SDFSGVSLTTA----QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
+ S +S +S T + G +G+ + +K+WD+ + GH
Sbjct: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 338
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V + F G ++ + A+D +++WD + + KT+ E++ + L F ++ Y+
Sbjct: 339 NWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVT 397
Query: 445 AGTD--VRVYLCR 455
D V+V+ CR
Sbjct: 398 GSVDQTVKVWECR 410
Score = 66.1 bits (154), Expect = 3e-10
Identities = 36/152 (23%), Positives = 74/152 (48%), Gaps = 3/152 (1%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T FHP + + +E++ +K+WD + GH V ISF +G LA+ +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
Query: 405 DSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKV 462
D +KLWD + + +T+ ++ + + +G ++ A D ++++ + +K
Sbjct: 171 DMTIKLWDFQGFECIRTMH-GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229
Query: 463 FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
F H VR ++ +AS S D+T++++
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 26/234 (11%)
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+P L H PVT + HP ++S S D D TG + + S+
Sbjct: 95 IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD-SV 153
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
F G + + + + +K+WD + + GH V+S++ NG ++ +A+ D
Sbjct: 154 QDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 213
Query: 406 SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL---------- 453
+K+W+++ KT + ++ + +Q GT +A D VRV++
Sbjct: 214 KTIKMWEVQTGYCVKTFTGHREW-VRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
Query: 454 --------CRQWQELKVFNDHTASATG---VRFGKNAQYLASTSMDRTLKLYGI 496
C W ++ + ATG + GK +L S S D+T+K++ +
Sbjct: 273 REHEHVVECISWAPESSYSS-ISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
>L13385-1|AAA02880.1| 410|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 410
Score = 86.6 bits (205), Expect = 2e-16
Identities = 65/291 (22%), Positives = 130/291 (44%), Gaps = 28/291 (9%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S +++ D V++ +T LKGHT V + + + + S D TI++W+
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
+ + HD V+ +++ P GD+++S S D+ +++TG V F+G
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYC---VKTFTGHREWV 237
Query: 348 AQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS-ENGY------- 397
P DG + + + + V++W + + A H V IS++ E+ Y
Sbjct: 238 RMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEAT 297
Query: 398 ------------YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+L + + D +K+WD+ T+ +N+ ++ + F G ++
Sbjct: 298 GSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW-VRGVLFHSGGKFILSC 356
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
D +RV+ + + +K N H T + F K A Y+ + S+D+T+K++
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 77.8 bits (183), Expect = 8e-14
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 2/193 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GH VTRVI+HP +++AS D TI+VW+ T L+ H V +S +G
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
+ S S+D D + + + + ++++ P+G + + + +K+W+++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDH-NVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
V F GH V + +++G +A+ + D V++W + K K E + ++
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-VVATKECKAELREHEHVVEC 281
Query: 433 LCFDQSGTYLAIA 445
+ + +Y +I+
Sbjct: 282 ISWAPESSYSSIS 294
Score = 74.9 bits (176), Expect = 6e-13
Identities = 58/253 (22%), Positives = 110/253 (43%), Gaps = 24/253 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTE--QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
DHS L + T+ D + + + + GH V+ V P+ D +++AS D TI++
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKM 218
Query: 284 WNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFS------DIRTGQLL 334
W V T H V + + G + S S+DQ W + ++R + +
Sbjct: 219 WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV 278
Query: 335 TKV------SDFSGVSLTTA----QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
+ S +S +S T + G +G+ + +K+WD+ + GH
Sbjct: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 338
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V + F G ++ + A+D +++WD + + KT+ E++ + L F ++ Y+
Sbjct: 339 NWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVT 397
Query: 445 AGTD--VRVYLCR 455
D V+V+ CR
Sbjct: 398 GSVDQTVKVWECR 410
Score = 66.1 bits (154), Expect = 3e-10
Identities = 36/152 (23%), Positives = 74/152 (48%), Gaps = 3/152 (1%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T FHP + + +E++ +K+WD + GH V ISF +G LA+ +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
Query: 405 DSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKV 462
D +KLWD + + +T+ ++ + + +G ++ A D ++++ + +K
Sbjct: 171 DMTIKLWDFQGFECIRTMH-GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229
Query: 463 FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
F H VR ++ +AS S D+T++++
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 26/234 (11%)
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+P L H PVT + HP ++S S D D TG + + S+
Sbjct: 95 IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD-SV 153
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
F G + + + + +K+WD + + GH V+S++ NG ++ +A+ D
Sbjct: 154 QDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 213
Query: 406 SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL---------- 453
+K+W+++ KT + ++ + +Q GT +A D VRV++
Sbjct: 214 KTIKMWEVQTGYCVKTFTGHREW-VRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
Query: 454 --------CRQWQELKVFNDHTASATG---VRFGKNAQYLASTSMDRTLKLYGI 496
C W ++ + ATG + GK +L S S D+T+K++ +
Sbjct: 273 REHEHVVECISWAPESSYSS-ISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
>BC064638-1|AAH64638.1| 410|Homo sapiens platelet-activating factor
acetylhydrolase, isoform Ib, alpha subunit 45kDa
protein.
Length = 410
Score = 86.6 bits (205), Expect = 2e-16
Identities = 65/291 (22%), Positives = 130/291 (44%), Gaps = 28/291 (9%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S +++ D V++ +T LKGHT V + + + + S D TI++W+
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
+ + HD V+ +++ P GD+++S S D+ +++TG V F+G
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYC---VKTFTGHREWV 237
Query: 348 AQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS-ENGY------- 397
P DG + + + + V++W + + A H V IS++ E+ Y
Sbjct: 238 RMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEAT 297
Query: 398 ------------YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+L + + D +K+WD+ T+ +N+ ++ + F G ++
Sbjct: 298 GSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW-VRGVLFHSGGKFILSC 356
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
D +RV+ + + +K N H T + F K A Y+ + S+D+T+K++
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 77.8 bits (183), Expect = 8e-14
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 2/193 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GH VTRVI+HP +++AS D TI+VW+ T L+ H V +S +G
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
+ S S+D D + + + + ++++ P+G + + + +K+W+++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDH-NVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
V F GH V + +++G +A+ + D V++W + K K E + ++
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-VVATKECKAELREHEHVVEC 281
Query: 433 LCFDQSGTYLAIA 445
+ + +Y +I+
Sbjct: 282 ISWAPESSYSSIS 294
Score = 74.9 bits (176), Expect = 6e-13
Identities = 58/253 (22%), Positives = 110/253 (43%), Gaps = 24/253 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTE--QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
DHS L + T+ D + + + + GH V+ V P+ D +++AS D TI++
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKM 218
Query: 284 WNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFS------DIRTGQLL 334
W V T H V + + G + S S+DQ W + ++R + +
Sbjct: 219 WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV 278
Query: 335 TKV------SDFSGVSLTTA----QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
+ S +S +S T + G +G+ + +K+WD+ + GH
Sbjct: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 338
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V + F G ++ + A+D +++WD + + KT+ E++ + L F ++ Y+
Sbjct: 339 NWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVT 397
Query: 445 AGTD--VRVYLCR 455
D V+V+ CR
Sbjct: 398 GSVDQTVKVWECR 410
Score = 66.1 bits (154), Expect = 3e-10
Identities = 36/152 (23%), Positives = 74/152 (48%), Gaps = 3/152 (1%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T FHP + + +E++ +K+WD + GH V ISF +G LA+ +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
Query: 405 DSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKV 462
D +KLWD + + +T+ ++ + + +G ++ A D ++++ + +K
Sbjct: 171 DMTIKLWDFQGFECIRTMH-GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229
Query: 463 FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
F H VR ++ +AS S D+T++++
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 26/234 (11%)
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+P L H PVT + HP ++S S D D TG + + S+
Sbjct: 95 IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD-SV 153
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
F G + + + + +K+WD + + GH V+S++ NG ++ +A+ D
Sbjct: 154 QDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 213
Query: 406 SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL---------- 453
+K+W+++ KT + ++ + +Q GT +A D VRV++
Sbjct: 214 KTIKMWEVQTGYCVKTFTGHREW-VRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
Query: 454 --------CRQWQELKVFNDHTASATG---VRFGKNAQYLASTSMDRTLKLYGI 496
C W ++ + ATG + GK +L S S D+T+K++ +
Sbjct: 273 REHEHVVECISWAPESSYSS-ISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
>AF400434-1|AAK92483.1| 410|Homo sapiens platelet-activating factor
acetyl hydrolase isoform Ib alpha subunit protein.
Length = 410
Score = 86.6 bits (205), Expect = 2e-16
Identities = 65/291 (22%), Positives = 130/291 (44%), Gaps = 28/291 (9%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S +++ D V++ +T LKGHT V + + + + S D TI++W+
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
+ + HD V+ +++ P GD+++S S D+ +++TG V F+G
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYC---VKTFTGHREWV 237
Query: 348 AQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS-ENGY------- 397
P DG + + + + V++W + + A H V IS++ E+ Y
Sbjct: 238 RMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEAT 297
Query: 398 ------------YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+L + + D +K+WD+ T+ +N+ ++ + F G ++
Sbjct: 298 GSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW-VRGVLFHSGGKFILSC 356
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
D +RV+ + + +K N H T + F K A Y+ + S+D+T+K++
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 77.8 bits (183), Expect = 8e-14
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 2/193 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GH VTRVI+HP +++AS D TI+VW+ T L+ H V +S +G
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
+ S S+D D + + + + ++++ P+G + + + +K+W+++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDH-NVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
V F GH V + +++G +A+ + D V++W + K K E + ++
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-VVATKECKAELREHEHVVEC 281
Query: 433 LCFDQSGTYLAIA 445
+ + +Y +I+
Sbjct: 282 ISWAPESSYSSIS 294
Score = 74.9 bits (176), Expect = 6e-13
Identities = 58/253 (22%), Positives = 110/253 (43%), Gaps = 24/253 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTE--QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
DHS L + T+ D + + + + GH V+ V P+ D +++AS D TI++
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKM 218
Query: 284 WNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFS------DIRTGQLL 334
W V T H V + + G + S S+DQ W + ++R + +
Sbjct: 219 WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV 278
Query: 335 TKV------SDFSGVSLTTA----QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
+ S +S +S T + G +G+ + +K+WD+ + GH
Sbjct: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 338
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V + F G ++ + A+D +++WD + + KT+ E++ + L F ++ Y+
Sbjct: 339 NWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVT 397
Query: 445 AGTD--VRVYLCR 455
D V+V+ CR
Sbjct: 398 GSVDQTVKVWECR 410
Score = 66.1 bits (154), Expect = 3e-10
Identities = 36/152 (23%), Positives = 74/152 (48%), Gaps = 3/152 (1%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T FHP + + +E++ +K+WD + GH V ISF +G LA+ +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
Query: 405 DSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKV 462
D +KLWD + + +T+ ++ + + +G ++ A D ++++ + +K
Sbjct: 171 DMTIKLWDFQGFECIRTMH-GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229
Query: 463 FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
F H VR ++ +AS S D+T++++
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 26/234 (11%)
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+P L H PVT + HP ++S S D D TG + + S+
Sbjct: 95 IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD-SV 153
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
F G + + + + +K+WD + + GH V+S++ NG ++ +A+ D
Sbjct: 154 QDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 213
Query: 406 SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL---------- 453
+K+W+++ KT + ++ + +Q GT +A D VRV++
Sbjct: 214 KTIKMWEVQTGYCVKTFTGHREW-VRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
Query: 454 --------CRQWQELKVFNDHTASATG---VRFGKNAQYLASTSMDRTLKLYGI 496
C W ++ + ATG + GK +L S S D+T+K++ +
Sbjct: 273 REHEHVVECISWAPESSYSS-ISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
>AF208837-1|AAL34972.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 86.6 bits (205), Expect = 2e-16
Identities = 65/291 (22%), Positives = 130/291 (44%), Gaps = 28/291 (9%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S +++ D V++ +T LKGHT V + + + + S D TI++W+
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQ 180
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
+ + HD V+ +++ P GD+++S S D+ +++TG V F+G
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYC---VKTFTGHREWV 237
Query: 348 AQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS-ENGY------- 397
P DG + + + + V++W + + A H V IS++ E+ Y
Sbjct: 238 RMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEAT 297
Query: 398 ------------YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+L + + D +K+WD+ T+ +N+ ++ + F G ++
Sbjct: 298 GSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW-VRGVLFHSGGKFILSC 356
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
D +RV+ + + +K N H T + F K A Y+ + S+D+T+K++
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 77.8 bits (183), Expect = 8e-14
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 2/193 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GH VTRVI+HP +++AS D TI+VW+ T L+ H V +S +G
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
+ S S+D D + + + + ++++ P+G + + + +K+W+++
Sbjct: 164 LLASCSADMTIKLWDFQGFECIRTMHGHDH-NVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
V F GH V + +++G +A+ + D V++W + K K E + ++
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-VVATKECKAELREHEHVVEC 281
Query: 433 LCFDQSGTYLAIA 445
+ + +Y +I+
Sbjct: 282 ISWAPESSYSSIS 294
Score = 74.9 bits (176), Expect = 6e-13
Identities = 58/253 (22%), Positives = 110/253 (43%), Gaps = 24/253 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTE--QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
DHS L + T+ D + + + + GH V+ V P+ D +++AS D TI++
Sbjct: 159 DHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKM 218
Query: 284 WNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFS------DIRTGQLL 334
W V T H V + + G + S S+DQ W + ++R + +
Sbjct: 219 WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV 278
Query: 335 TKV------SDFSGVSLTTA----QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
+ S +S +S T + G +G+ + +K+WD+ + GH
Sbjct: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 338
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V + F G ++ + A+D +++WD + + KT+ E++ + L F ++ Y+
Sbjct: 339 NWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVT 397
Query: 445 AGTD--VRVYLCR 455
D V+V+ CR
Sbjct: 398 GSVDQTVKVWECR 410
Score = 66.1 bits (154), Expect = 3e-10
Identities = 36/152 (23%), Positives = 74/152 (48%), Gaps = 3/152 (1%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T FHP + + +E++ +K+WD + GH V ISF +G LA+ +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
Query: 405 DSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKV 462
D +KLWD + + +T+ ++ + + +G ++ A D ++++ + +K
Sbjct: 171 DMTIKLWDFQGFECIRTMH-GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229
Query: 463 FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
F H VR ++ +AS S D+T++++
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 62.9 bits (146), Expect = 3e-09
Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 26/234 (11%)
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+P L H PVT + HP ++S S D D TG + + S+
Sbjct: 95 IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD-SV 153
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
F G + + + + +K+WD + + GH V+S++ NG ++ +A+ D
Sbjct: 154 QDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 213
Query: 406 SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL---------- 453
+K+W+++ KT + ++ + +Q GT +A D VRV++
Sbjct: 214 KTIKMWEVQTGYCVKTFTGHREW-VRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
Query: 454 --------CRQWQELKVFNDHTASATG---VRFGKNAQYLASTSMDRTLKLYGI 496
C W ++ + ATG + GK +L S S D+T+K++ +
Sbjct: 273 REHEHVVECISWAPESSYSS-ISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
>EF011621-1|ABK41111.1| 357|Homo sapiens CDW11/WDR57 protein.
Length = 357
Score = 86.2 bits (204), Expect = 2e-16
Identities = 77/281 (27%), Positives = 119/281 (42%), Gaps = 13/281 (4%)
Query: 228 SKLLTGGNDRNATVFNKDTE-QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S L + G DR ++N + A LKGH+ V + Y+ D + +AS D T+ VW+
Sbjct: 79 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGVSL 345
T + L+ H V G ++ T SD DIR + + V
Sbjct: 139 ETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLA 198
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
T D +I G G +N +K+WDL++ GH VT +S S G YL + A D
Sbjct: 199 VTFNDTSDQIISG-GIDN-DIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMD 256
Query: 406 SCVKLWDLR----KLKNFKTIQLEENYAIKEL--C-FDQSGTYLAIAGTDVRVYLCRQWQ 458
+ V++WD+R K + K Q + K L C + G+ +A D VY+
Sbjct: 257 NTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTS 316
Query: 459 ELKVFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++ H S V F + + S S D+ L + I+
Sbjct: 317 RRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 81.4 bits (192), Expect = 7e-15
Identities = 69/280 (24%), Positives = 131/280 (46%), Gaps = 21/280 (7%)
Query: 176 LTQERKRRGRTLPEGLLAPEQIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTGGN 235
+ +++KR+G LP L+ ++ R L L + G PG P LL G
Sbjct: 1 MIEQQKRKGPELP--LVPVKRQRHELLLGAGSG------PGAGQQQATPG---ALLQAGP 49
Query: 236 DRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAI 294
R +++ + + +L GH +V +HP+ T+ +A D I +WNV A
Sbjct: 50 PRCSSL-----QAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT 104
Query: 295 LRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG 354
L+ H G V L + G + S S+D+ A D TG+ + ++ + +
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP 164
Query: 355 LIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ TG+++ VK+WD+++++ + F + V +++F++ + + D+ +K+WDLR
Sbjct: 165 QLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR 223
Query: 415 KLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVY 452
+ K T++ + ++ L G+YL D VRV+
Sbjct: 224 QNKLTYTMRGHAD-SVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/53 (35%), Positives = 30/53 (56%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
D SK+ G DR V++ + +++ L GH + V +HPDE +I+AS D
Sbjct: 296 DGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
>BC001494-1|AAH01494.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 86.2 bits (204), Expect = 2e-16
Identities = 77/281 (27%), Positives = 119/281 (42%), Gaps = 13/281 (4%)
Query: 228 SKLLTGGNDRNATVFNKDTE-QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S L + G DR ++N + A LKGH+ V + Y+ D + +AS D T+ VW+
Sbjct: 79 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGVSL 345
T + L+ H V G ++ T SD DIR + + V
Sbjct: 139 ETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLA 198
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
T D +I G G +N +K+WDL++ GH VT +S S G YL + A D
Sbjct: 199 VTFNDTSDQIISG-GIDN-DIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMD 256
Query: 406 SCVKLWDLR----KLKNFKTIQLEENYAIKEL--C-FDQSGTYLAIAGTDVRVYLCRQWQ 458
+ V++WD+R K + K Q + K L C + G+ +A D VY+
Sbjct: 257 NTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTS 316
Query: 459 ELKVFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++ H S V F + + S S D+ L + I+
Sbjct: 317 RRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 81.4 bits (192), Expect = 7e-15
Identities = 69/280 (24%), Positives = 131/280 (46%), Gaps = 21/280 (7%)
Query: 176 LTQERKRRGRTLPEGLLAPEQIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTGGN 235
+ +++KR+G LP L+ ++ R L L + G PG P LL G
Sbjct: 1 MIEQQKRKGPELP--LVPVKRQRHELLLGAGSG------PGAGQQQATPG---ALLQAGP 49
Query: 236 DRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAI 294
R +++ + + +L GH +V +HP+ T+ +A D I +WNV A
Sbjct: 50 PRCSSL-----QAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT 104
Query: 295 LRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG 354
L+ H G V L + G + S S+D+ A D TG+ + ++ + +
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP 164
Query: 355 LIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ TG+++ VK+WD+++++ + F + V +++F++ + + D+ +K+WDLR
Sbjct: 165 QLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR 223
Query: 415 KLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVY 452
+ K T++ + ++ L G+YL D VRV+
Sbjct: 224 QNKLTYTMRGHAD-SVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/53 (35%), Positives = 30/53 (56%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
D SK+ G DR V++ + +++ L GH + V +HPDE +I+AS D
Sbjct: 296 DGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
>AL451070-1|CAH71848.1| 357|Homo sapiens WD repeat domain 57 (U5
snRNP specific) protein.
Length = 357
Score = 86.2 bits (204), Expect = 2e-16
Identities = 77/281 (27%), Positives = 119/281 (42%), Gaps = 13/281 (4%)
Query: 228 SKLLTGGNDRNATVFNKDTE-QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S L + G DR ++N + A LKGH+ V + Y+ D + +AS D T+ VW+
Sbjct: 79 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGVSL 345
T + L+ H V G ++ T SD DIR + + V
Sbjct: 139 ETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLA 198
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
T D +I G G +N +K+WDL++ GH VT +S S G YL + A D
Sbjct: 199 VTFNDTSDQIISG-GIDN-DIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMD 256
Query: 406 SCVKLWDLR----KLKNFKTIQLEENYAIKEL--C-FDQSGTYLAIAGTDVRVYLCRQWQ 458
+ V++WD+R K + K Q + K L C + G+ +A D VY+
Sbjct: 257 NTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTS 316
Query: 459 ELKVFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++ H S V F + + S S D+ L + I+
Sbjct: 317 RRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 81.4 bits (192), Expect = 7e-15
Identities = 69/280 (24%), Positives = 131/280 (46%), Gaps = 21/280 (7%)
Query: 176 LTQERKRRGRTLPEGLLAPEQIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTGGN 235
+ +++KR+G LP L+ ++ R L L + G PG P LL G
Sbjct: 1 MIEQQKRKGPELP--LVPVKRQRHELLLGAGSG------PGAGQQQATPG---ALLQAGP 49
Query: 236 DRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAI 294
R +++ + + +L GH +V +HP+ T+ +A D I +WNV A
Sbjct: 50 PRCSSL-----QAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYAT 104
Query: 295 LRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG 354
L+ H G V L + G + S S+D+ A D TG+ + ++ + +
Sbjct: 105 LKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP 164
Query: 355 LIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR 414
+ TG+++ VK+WD+++++ + F + V +++F++ + + D+ +K+WDLR
Sbjct: 165 QLVCTGSDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLR 223
Query: 415 KLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVY 452
+ K T++ + ++ L G+YL D VRV+
Sbjct: 224 QNKLTYTMRGHAD-SVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 43.6 bits (98), Expect = 0.002
Identities = 19/53 (35%), Positives = 30/53 (56%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPD 278
D SK+ G DR V++ + +++ L GH + V +HPDE +I+AS D
Sbjct: 296 DGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
>AB053276-1|BAB69430.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 85.8 bits (203), Expect = 3e-16
Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 1/156 (0%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
HT V + PD +++ S D TI++W+ Q G + +P+G +
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
S SDQ D+R +LL SG + FHP G T + + +KI DL E
Sbjct: 73 SAGSDQTVKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLITASSDGTLKILDLLEGR 131
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
+ GH GPV ++SFS+ G A+ D+ V LW
Sbjct: 132 LIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 167
Score = 74.1 bits (174), Expect = 1e-12
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 3/149 (2%)
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
A+F PDG + + +E+ +KIWD + V NF VG + F+ +G +A+A D
Sbjct: 20 AKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQT 79
Query: 408 VKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFND 465
VK+WD+R K + Q+ + + F SG YL A +D +++ + + +
Sbjct: 80 VKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQG 138
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLY 494
HT V F K + AS D + L+
Sbjct: 139 HTGPVFTVSFSKGGELFASGGADTQVLLW 167
Score = 67.7 bits (158), Expect = 9e-11
Identities = 35/144 (24%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D +++ D+ +++ +Q V V ++P + +A D T++VW+
Sbjct: 25 DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWD 84
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V ++ + H G V +S HP+G+Y+++ SSD D+ G+L+ + +G +
Sbjct: 85 VRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTG-PV 143
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW 369
T F G +F +G ++QV +W
Sbjct: 144 FTVSFSKGGELFASGGADTQVLLW 167
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H V FS +G + + +ED +K+WD + +A + F+ SGT +
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFA-NFVDFNPSGTCI 71
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
A AG+D V+V+ R + L+ + H+ + F + YL + S D TLK+
Sbjct: 72 ASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKI 124
>AB053266-1|BAB69057.1| 348|Homo sapiens TUWD12 protein.
Length = 348
Score = 85.8 bits (203), Expect = 3e-16
Identities = 48/156 (30%), Positives = 71/156 (45%), Gaps = 1/156 (0%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
HT V + PD +++ S D TI++W+ Q G + +P+G +
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIA 72
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
S SDQ D+R +LL SG + FHP G T + + +KI DL E
Sbjct: 73 SAGSDQTVKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLITASSDGTLKILDLLEGR 131
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
+ GH GPV ++SFS+ G A+ D+ V LW
Sbjct: 132 LIYTLQGHTGPVFTVSFSKGGELFASGGADTQVLLW 167
Score = 74.1 bits (174), Expect = 1e-12
Identities = 43/149 (28%), Positives = 71/149 (47%), Gaps = 3/149 (2%)
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
A+F PDG + + +E+ +KIWD + V NF VG + F+ +G +A+A D
Sbjct: 20 AKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQT 79
Query: 408 VKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFND 465
VK+WD+R K + Q+ + + F SG YL A +D +++ + + +
Sbjct: 80 VKVWDVRVNKLLQHYQVHSG-GVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQG 138
Query: 466 HTASATGVRFGKNAQYLASTSMDRTLKLY 494
HT V F K + AS D + L+
Sbjct: 139 HTGPVFTVSFSKGGELFASGGADTQVLLW 167
Score = 67.7 bits (158), Expect = 9e-11
Identities = 35/144 (24%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D +++ D+ +++ +Q V V ++P + +A D T++VW+
Sbjct: 25 DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWD 84
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
V ++ + H G V +S HP+G+Y+++ SSD D+ G+L+ + +G +
Sbjct: 85 VRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTG-PV 143
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW 369
T F G +F +G ++QV +W
Sbjct: 144 FTVSFSKGGELFASGGADTQVLLW 167
Score = 50.0 bits (114), Expect = 2e-05
Identities = 32/113 (28%), Positives = 54/113 (47%), Gaps = 3/113 (2%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H V FS +G + + +ED +K+WD + +A + F+ SGT +
Sbjct: 13 HTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFA-NFVDFNPSGTCI 71
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
A AG+D V+V+ R + L+ + H+ + F + YL + S D TLK+
Sbjct: 72 ASAGSDQTVKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKI 124
>L13387-1|AAA02882.1| 288|Homo sapiens Miller-Dieker lissencephaly
protein protein.
Length = 288
Score = 84.6 bits (200), Expect = 7e-16
Identities = 64/289 (22%), Positives = 128/289 (44%), Gaps = 28/289 (9%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTS 289
+++ D V++ +T LKGHT V + + + + S D TI++W+
Sbjct: 1 MVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGF 60
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
+ + HD V+ +++ P GD+++S S D+ +++TG V F+G
Sbjct: 61 ECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYC---VKTFTGHREWVRM 117
Query: 350 FHP--DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS-ENGY--------- 397
P DG + + + + V++W + + A H V IS++ E+ Y
Sbjct: 118 VRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGS 177
Query: 398 ----------YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGT 447
+L + + D +K+WD+ T +N+ ++ + F G ++
Sbjct: 178 ETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXVGHDNW-VRGVLFHSGGKFILSCAD 236
Query: 448 D--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
D +RV+ + + +K N H T + F K A Y+ + S+D+T+K++
Sbjct: 237 DKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 285
Score = 74.5 bits (175), Expect = 8e-13
Identities = 58/253 (22%), Positives = 110/253 (43%), Gaps = 24/253 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTE--QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
DHS L + T+ D + + + + GH V+ V P+ D +++AS D TI++
Sbjct: 37 DHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKM 96
Query: 284 WNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFS------DIRTGQLL 334
W V T H V + + G + S S+DQ W + ++R + +
Sbjct: 97 WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV 156
Query: 335 TKV------SDFSGVSLTTA----QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
+ S +S +S T + G +G+ + +K+WD+ + GH
Sbjct: 157 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTXVGHD 216
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V + F G ++ + A+D +++WD + + KT+ E++ + L F ++ Y+
Sbjct: 217 NWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVT 275
Query: 445 AGTD--VRVYLCR 455
D V+V+ CR
Sbjct: 276 GSVDQTVKVWECR 288
>U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein.
Length = 1224
Score = 83.8 bits (198), Expect = 1e-15
Identities = 62/226 (27%), Positives = 99/226 (43%), Gaps = 29/226 (12%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
++GG+D V+N + + L GH + +H + +++AS D TIRVWN +
Sbjct: 67 VSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIR-----TGQLLTKVSDFSG 342
+L H+ V HPT D V+S S DQ W S +R G + + V +G
Sbjct: 127 CVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
Query: 343 VSL--TT-----------------AQFHPDGLIFGTGTENSQVKIWDLKEQS--NVANFP 381
V L TT A FHP + +G ++ QVKIW + E V
Sbjct: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEEN 427
GH V+ F + + +ED +++WD+ K +T + + +
Sbjct: 247 GHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHD 292
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/159 (20%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTS 318
+V + +HP ++T+ + I++W+ HDGPV G+ H +S
Sbjct: 11 RVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGG 70
Query: 319 SDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVA 378
D + + + L + TT FH + + +++ +++W+ + ++ V
Sbjct: 71 DDYKIKVWNYKLRRCLFTLLGHLDYIRTTF-FHHEYPWILSASDDQTIRVWNWQSRTCVC 129
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLK 417
GH V F + +A+ D V++WD+ L+
Sbjct: 130 VLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLR 168
Score = 49.2 bits (112), Expect = 3e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 3/149 (2%)
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
FHP T N +++WD + + + F H GPV I F + + +D +K
Sbjct: 17 FHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIK 76
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHT 467
+W+ + + T+ +Y I+ F ++ A D +RV+ + + V H
Sbjct: 77 VWNYKLRRCLFTLLGHLDY-IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHN 135
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+F + S S+D+T++++ I
Sbjct: 136 HYVMCAQFHPTEDLVVSASLDQTVRVWDI 164
Score = 44.8 bits (101), Expect = 7e-04
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 246 TEQVVA-ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAI--LRSHDGPV 302
T+ VV +L+GH + V +HP +++ + D +++W + S+ + R H V
Sbjct: 193 TDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
+ HP + +LS S D+ W S RTG + T D + A HP+ +F
Sbjct: 253 SCAVFHPRQELILSNSEDKSIRVWDMSK-RTG-VQTFRRDHDRFWVLAA--HPNLNLFAA 308
Query: 360 GTENSQV 366
G + +
Sbjct: 309 GHDGGMI 315
Score = 41.9 bits (94), Expect = 0.005
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 230 LLTGGNDRNATVF--NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++G +DR ++ N+ V +GH V+ ++HP ++ +++ S D +IRVW++
Sbjct: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
Query: 288 TSQTTAILRSHDGPVTGLSLHP 309
R L+ HP
Sbjct: 280 KRTGVQTFRRDHDRFWVLAAHP 301
Score = 41.1 bits (92), Expect = 0.009
Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 7/132 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H V + +H + ++ D+ I+VWN + L H + H ++L
Sbjct: 50 HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL 109
Query: 316 STSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
S S DQ W + +LT + + + AQFHP + + + + V++WD+
Sbjct: 110 SASDDQTIRVWNWQSRTCVCVLTGHNHY----VMCAQFHPTEDLVVSASLDQTVRVWDIS 165
Query: 373 EQSNVANFPGHV 384
PG V
Sbjct: 166 GLRKKNLSPGAV 177
>BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein.
Length = 1233
Score = 83.8 bits (198), Expect = 1e-15
Identities = 62/226 (27%), Positives = 99/226 (43%), Gaps = 29/226 (12%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
++GG+D V+N + + L GH + +H + +++AS D TIRVWN +
Sbjct: 67 VSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIR-----TGQLLTKVSDFSG 342
+L H+ V HPT D V+S S DQ W S +R G + + V +G
Sbjct: 127 CVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
Query: 343 VSL--TT-----------------AQFHPDGLIFGTGTENSQVKIWDLKEQS--NVANFP 381
V L TT A FHP + +G ++ QVKIW + E V
Sbjct: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEEN 427
GH V+ F + + +ED +++WD+ K +T + + +
Sbjct: 247 GHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHD 292
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/159 (20%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTS 318
+V + +HP ++T+ + I++W+ HDGPV G+ H +S
Sbjct: 11 RVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGG 70
Query: 319 SDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVA 378
D + + + L + TT FH + + +++ +++W+ + ++ V
Sbjct: 71 DDYKIKVWNYKLRRCLFTLLGHLDYIRTTF-FHHEYPWILSASDDQTIRVWNWQSRTCVC 129
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLK 417
GH V F + +A+ D V++WD+ L+
Sbjct: 130 VLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLR 168
Score = 49.2 bits (112), Expect = 3e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 3/149 (2%)
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
FHP T N +++WD + + + F H GPV I F + + +D +K
Sbjct: 17 FHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIK 76
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHT 467
+W+ + + T+ +Y I+ F ++ A D +RV+ + + V H
Sbjct: 77 VWNYKLRRCLFTLLGHLDY-IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHN 135
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+F + S S+D+T++++ I
Sbjct: 136 HYVMCAQFHPTEDLVVSASLDQTVRVWDI 164
Score = 44.8 bits (101), Expect = 7e-04
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 246 TEQVVA-ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAI--LRSHDGPV 302
T+ VV +L+GH + V +HP +++ + D +++W + S+ + R H V
Sbjct: 193 TDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
+ HP + +LS S D+ W S RTG + T D + A HP+ +F
Sbjct: 253 SCAVFHPRQELILSNSEDKSIRVWDMSK-RTG-VQTFRRDHDRFWVLAA--HPNLNLFAA 308
Query: 360 GTENSQV 366
G + +
Sbjct: 309 GHDGGMI 315
Score = 41.9 bits (94), Expect = 0.005
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 230 LLTGGNDRNATVF--NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++G +DR ++ N+ V +GH V+ ++HP ++ +++ S D +IRVW++
Sbjct: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
Query: 288 TSQTTAILRSHDGPVTGLSLHP 309
R L+ HP
Sbjct: 280 KRTGVQTFRRDHDRFWVLAAHP 301
Score = 41.1 bits (92), Expect = 0.009
Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 7/132 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H V + +H + ++ D+ I+VWN + L H + H ++L
Sbjct: 50 HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL 109
Query: 316 STSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
S S DQ W + +LT + + + AQFHP + + + + V++WD+
Sbjct: 110 SASDDQTIRVWNWQSRTCVCVLTGHNHY----VMCAQFHPTEDLVVSASLDQTVRVWDIS 165
Query: 373 EQSNVANFPGHV 384
PG V
Sbjct: 166 GLRKKNLSPGAV 177
>AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1233
Score = 83.8 bits (198), Expect = 1e-15
Identities = 62/226 (27%), Positives = 99/226 (43%), Gaps = 29/226 (12%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
++GG+D V+N + + L GH + +H + +++AS D TIRVWN +
Sbjct: 67 VSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIR-----TGQLLTKVSDFSG 342
+L H+ V HPT D V+S S DQ W S +R G + + V +G
Sbjct: 127 CVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
Query: 343 VSL--TT-----------------AQFHPDGLIFGTGTENSQVKIWDLKEQS--NVANFP 381
V L TT A FHP + +G ++ QVKIW + E V
Sbjct: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEEN 427
GH V+ F + + +ED +++WD+ K +T + + +
Sbjct: 247 GHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHD 292
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/159 (20%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTS 318
+V + +HP ++T+ + I++W+ HDGPV G+ H +S
Sbjct: 11 RVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGG 70
Query: 319 SDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVA 378
D + + + L + TT FH + + +++ +++W+ + ++ V
Sbjct: 71 DDYKIKVWNYKLRRCLFTLLGHLDYIRTTF-FHHEYPWILSASDDQTIRVWNWQSRTCVC 129
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLK 417
GH V F + +A+ D V++WD+ L+
Sbjct: 130 VLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLR 168
Score = 49.2 bits (112), Expect = 3e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 3/149 (2%)
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
FHP T N +++WD + + + F H GPV I F + + +D +K
Sbjct: 17 FHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIK 76
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHT 467
+W+ + + T+ +Y I+ F ++ A D +RV+ + + V H
Sbjct: 77 VWNYKLRRCLFTLLGHLDY-IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHN 135
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+F + S S+D+T++++ I
Sbjct: 136 HYVMCAQFHPTEDLVVSASLDQTVRVWDI 164
Score = 44.8 bits (101), Expect = 7e-04
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 246 TEQVVA-ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAI--LRSHDGPV 302
T+ VV +L+GH + V +HP +++ + D +++W + S+ + R H V
Sbjct: 193 TDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
+ HP + +LS S D+ W S RTG + T D + A HP+ +F
Sbjct: 253 SCAVFHPRQELILSNSEDKSIRVWDMSK-RTG-VQTFRRDHDRFWVLAA--HPNLNLFAA 308
Query: 360 GTENSQV 366
G + +
Sbjct: 309 GHDGGMI 315
Score = 41.9 bits (94), Expect = 0.005
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 230 LLTGGNDRNATVF--NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++G +DR ++ N+ V +GH V+ ++HP ++ +++ S D +IRVW++
Sbjct: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
Query: 288 TSQTTAILRSHDGPVTGLSLHP 309
R L+ HP
Sbjct: 280 KRTGVQTFRRDHDRFWVLAAHP 301
Score = 41.1 bits (92), Expect = 0.009
Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 7/132 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H V + +H + ++ D+ I+VWN + L H + H ++L
Sbjct: 50 HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL 109
Query: 316 STSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
S S DQ W + +LT + + + AQFHP + + + + V++WD+
Sbjct: 110 SASDDQTIRVWNWQSRTCVCVLTGHNHY----VMCAQFHPTEDLVVSASLDQTVRVWDIS 165
Query: 373 EQSNVANFPGHV 384
PG V
Sbjct: 166 GLRKKNLSPGAV 177
>AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1224
Score = 83.8 bits (198), Expect = 1e-15
Identities = 62/226 (27%), Positives = 99/226 (43%), Gaps = 29/226 (12%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
++GG+D V+N + + L GH + +H + +++AS D TIRVWN +
Sbjct: 67 VSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIR-----TGQLLTKVSDFSG 342
+L H+ V HPT D V+S S DQ W S +R G + + V +G
Sbjct: 127 CVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
Query: 343 VSL--TT-----------------AQFHPDGLIFGTGTENSQVKIWDLKEQS--NVANFP 381
V L TT A FHP + +G ++ QVKIW + E V
Sbjct: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEEN 427
GH V+ F + + +ED +++WD+ K +T + + +
Sbjct: 247 GHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHD 292
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/159 (20%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTS 318
+V + +HP ++T+ + I++W+ HDGPV G+ H +S
Sbjct: 11 RVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGG 70
Query: 319 SDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVA 378
D + + + L + TT FH + + +++ +++W+ + ++ V
Sbjct: 71 DDYKIKVWNYKLRRCLFTLLGHLDYIRTTF-FHHEYPWILSASDDQTIRVWNWQSRTCVC 129
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLK 417
GH V F + +A+ D V++WD+ L+
Sbjct: 130 VLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLR 168
Score = 49.2 bits (112), Expect = 3e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 3/149 (2%)
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
FHP T N +++WD + + + F H GPV I F + + +D +K
Sbjct: 17 FHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIK 76
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHT 467
+W+ + + T+ +Y I+ F ++ A D +RV+ + + V H
Sbjct: 77 VWNYKLRRCLFTLLGHLDY-IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHN 135
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+F + S S+D+T++++ I
Sbjct: 136 HYVMCAQFHPTEDLVVSASLDQTVRVWDI 164
Score = 44.8 bits (101), Expect = 7e-04
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 246 TEQVVA-ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAI--LRSHDGPV 302
T+ VV +L+GH + V +HP +++ + D +++W + S+ + R H V
Sbjct: 193 TDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
+ HP + +LS S D+ W S RTG + T D + A HP+ +F
Sbjct: 253 SCAVFHPRQELILSNSEDKSIRVWDMSK-RTG-VQTFRRDHDRFWVLAA--HPNLNLFAA 308
Query: 360 GTENSQV 366
G + +
Sbjct: 309 GHDGGMI 315
Score = 41.9 bits (94), Expect = 0.005
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 230 LLTGGNDRNATVF--NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++G +DR ++ N+ V +GH V+ ++HP ++ +++ S D +IRVW++
Sbjct: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
Query: 288 TSQTTAILRSHDGPVTGLSLHP 309
R L+ HP
Sbjct: 280 KRTGVQTFRRDHDRFWVLAAHP 301
Score = 41.1 bits (92), Expect = 0.009
Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 7/132 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H V + +H + ++ D+ I+VWN + L H + H ++L
Sbjct: 50 HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL 109
Query: 316 STSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
S S DQ W + +LT + + + AQFHP + + + + V++WD+
Sbjct: 110 SASDDQTIRVWNWQSRTCVCVLTGHNHY----VMCAQFHPTEDLVVSASLDQTVRVWDIS 165
Query: 373 EQSNVANFPGHV 384
PG V
Sbjct: 166 GLRKKNLSPGAV 177
>AL445230-2|CAI15005.1| 1224|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1224
Score = 83.8 bits (198), Expect = 1e-15
Identities = 62/226 (27%), Positives = 99/226 (43%), Gaps = 29/226 (12%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
++GG+D V+N + + L GH + +H + +++AS D TIRVWN +
Sbjct: 67 VSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIR-----TGQLLTKVSDFSG 342
+L H+ V HPT D V+S S DQ W S +R G + + V +G
Sbjct: 127 CVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
Query: 343 VSL--TT-----------------AQFHPDGLIFGTGTENSQVKIWDLKEQS--NVANFP 381
V L TT A FHP + +G ++ QVKIW + E V
Sbjct: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEEN 427
GH V+ F + + +ED +++WD+ K +T + + +
Sbjct: 247 GHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHD 292
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/159 (20%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTS 318
+V + +HP ++T+ + I++W+ HDGPV G+ H +S
Sbjct: 11 RVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGG 70
Query: 319 SDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVA 378
D + + + L + TT FH + + +++ +++W+ + ++ V
Sbjct: 71 DDYKIKVWNYKLRRCLFTLLGHLDYIRTTF-FHHEYPWILSASDDQTIRVWNWQSRTCVC 129
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLK 417
GH V F + +A+ D V++WD+ L+
Sbjct: 130 VLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLR 168
Score = 49.2 bits (112), Expect = 3e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 3/149 (2%)
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
FHP T N +++WD + + + F H GPV I F + + +D +K
Sbjct: 17 FHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIK 76
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHT 467
+W+ + + T+ +Y I+ F ++ A D +RV+ + + V H
Sbjct: 77 VWNYKLRRCLFTLLGHLDY-IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHN 135
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+F + S S+D+T++++ I
Sbjct: 136 HYVMCAQFHPTEDLVVSASLDQTVRVWDI 164
Score = 44.8 bits (101), Expect = 7e-04
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 246 TEQVVA-ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAI--LRSHDGPV 302
T+ VV +L+GH + V +HP +++ + D +++W + S+ + R H V
Sbjct: 193 TDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
+ HP + +LS S D+ W S RTG + T D + A HP+ +F
Sbjct: 253 SCAVFHPRQELILSNSEDKSIRVWDMSK-RTG-VQTFRRDHDRFWVLAA--HPNLNLFAA 308
Query: 360 GTENSQV 366
G + +
Sbjct: 309 GHDGGMI 315
Score = 41.9 bits (94), Expect = 0.005
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 230 LLTGGNDRNATVF--NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++G +DR ++ N+ V +GH V+ ++HP ++ +++ S D +IRVW++
Sbjct: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
Query: 288 TSQTTAILRSHDGPVTGLSLHP 309
R L+ HP
Sbjct: 280 KRTGVQTFRRDHDRFWVLAAHP 301
Score = 41.1 bits (92), Expect = 0.009
Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 7/132 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H V + +H + ++ D+ I+VWN + L H + H ++L
Sbjct: 50 HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL 109
Query: 316 STSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
S S DQ W + +LT + + + AQFHP + + + + V++WD+
Sbjct: 110 SASDDQTIRVWNWQSRTCVCVLTGHNHY----VMCAQFHPTEDLVVSASLDQTVRVWDIS 165
Query: 373 EQSNVANFPGHV 384
PG V
Sbjct: 166 GLRKKNLSPGAV 177
>AL445230-1|CAI15004.1| 1233|Homo sapiens coatomer protein complex,
subunit alpha protein.
Length = 1233
Score = 83.8 bits (198), Expect = 1e-15
Identities = 62/226 (27%), Positives = 99/226 (43%), Gaps = 29/226 (12%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
++GG+D V+N + + L GH + +H + +++AS D TIRVWN +
Sbjct: 67 VSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRT 126
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIR-----TGQLLTKVSDFSG 342
+L H+ V HPT D V+S S DQ W S +R G + + V +G
Sbjct: 127 CVCVLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITG 186
Query: 343 VSL--TT-----------------AQFHPDGLIFGTGTENSQVKIWDLKEQS--NVANFP 381
V L TT A FHP + +G ++ QVKIW + E V
Sbjct: 187 VDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCR 246
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEEN 427
GH V+ F + + +ED +++WD+ K +T + + +
Sbjct: 247 GHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHD 292
Score = 50.4 bits (115), Expect = 1e-05
Identities = 32/159 (20%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTS 318
+V + +HP ++T+ + I++W+ HDGPV G+ H +S
Sbjct: 11 RVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGG 70
Query: 319 SDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVA 378
D + + + L + TT FH + + +++ +++W+ + ++ V
Sbjct: 71 DDYKIKVWNYKLRRCLFTLLGHLDYIRTTF-FHHEYPWILSASDDQTIRVWNWQSRTCVC 129
Query: 379 NFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLK 417
GH V F + +A+ D V++WD+ L+
Sbjct: 130 VLTGHNHYVMCAQFHPTEDLVVSASLDQTVRVWDISGLR 168
Score = 49.2 bits (112), Expect = 3e-05
Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 3/149 (2%)
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVK 409
FHP T N +++WD + + + F H GPV I F + + +D +K
Sbjct: 17 FHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIK 76
Query: 410 LWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHT 467
+W+ + + T+ +Y I+ F ++ A D +RV+ + + V H
Sbjct: 77 VWNYKLRRCLFTLLGHLDY-IRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHN 135
Query: 468 ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+F + S S+D+T++++ I
Sbjct: 136 HYVMCAQFHPTEDLVVSASLDQTVRVWDI 164
Score = 44.8 bits (101), Expect = 7e-04
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 246 TEQVVA-ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAI--LRSHDGPV 302
T+ VV +L+GH + V +HP +++ + D +++W + S+ + R H V
Sbjct: 193 TDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNV 252
Query: 303 TGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGT 359
+ HP + +LS S D+ W S RTG + T D + A HP+ +F
Sbjct: 253 SCAVFHPRQELILSNSEDKSIRVWDMSK-RTG-VQTFRRDHDRFWVLAA--HPNLNLFAA 308
Query: 360 GTENSQV 366
G + +
Sbjct: 309 GHDGGMI 315
Score = 41.9 bits (94), Expect = 0.005
Identities = 20/82 (24%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 230 LLTGGNDRNATVF--NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++G +DR ++ N+ V +GH V+ ++HP ++ +++ S D +IRVW++
Sbjct: 220 IVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMS 279
Query: 288 TSQTTAILRSHDGPVTGLSLHP 309
R L+ HP
Sbjct: 280 KRTGVQTFRRDHDRFWVLAAHP 301
Score = 41.1 bits (92), Expect = 0.009
Identities = 30/132 (22%), Positives = 53/132 (40%), Gaps = 7/132 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H V + +H + ++ D+ I+VWN + L H + H ++L
Sbjct: 50 HDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWIL 109
Query: 316 STSSDQH---WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
S S DQ W + +LT + + + AQFHP + + + + V++WD+
Sbjct: 110 SASDDQTIRVWNWQSRTCVCVLTGHNHY----VMCAQFHPTEDLVVSASLDQTVRVWDIS 165
Query: 373 EQSNVANFPGHV 384
PG V
Sbjct: 166 GLRKKNLSPGAV 177
>AF090988-1|AAC69625.1| 357|Homo sapiens U5 snRNP-specific 40 kDa
protein protein.
Length = 357
Score = 83.8 bits (198), Expect = 1e-15
Identities = 76/281 (27%), Positives = 118/281 (41%), Gaps = 13/281 (4%)
Query: 228 SKLLTGGNDRNATVFNKDTE-QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S L + G DR ++N + A LKGH+ V + Y+ D + +AS D T+ VW+
Sbjct: 79 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 138
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGVSL 345
T + L+ H V ++ T SD DIR + + V
Sbjct: 139 ETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLA 198
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
T D +I G G +N +K+WDL++ GH VT +S S G YL + A D
Sbjct: 199 VTFNDTSDQIISG-GIDN-DIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMD 256
Query: 406 SCVKLWDLR----KLKNFKTIQLEENYAIKEL--C-FDQSGTYLAIAGTDVRVYLCRQWQ 458
+ V++WD+R K + K Q + K L C + G+ +A D VY+
Sbjct: 257 NTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTS 316
Query: 459 ELKVFN--DHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++ H S V F + + S S D+ L + I+
Sbjct: 317 RRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYMGEIQ 357
Score = 81.8 bits (193), Expect = 5e-15
Identities = 52/206 (25%), Positives = 101/206 (49%), Gaps = 5/206 (2%)
Query: 250 VAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSLH 308
+ +L GH +V +HP+ T+ +A D I +WNV A L+ H G V L +
Sbjct: 59 IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYN 118
Query: 309 PTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKI 368
G + S S+D+ A D TG+ + ++ + + + TG+++ VK+
Sbjct: 119 TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDGTVKL 178
Query: 369 WDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENY 428
WD+++++ + F + V +++F++ + + D+ +K+WDLR+ K T++ +
Sbjct: 179 WDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD- 236
Query: 429 AIKELCFDQSGTYLAIAGTD--VRVY 452
++ L G+YL D VRV+
Sbjct: 237 SVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 60.9 bits (141), Expect = 1e-08
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 13/246 (5%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVI-YHPDEDTVITA 275
++ L N +D S L + D+ V++ +T + V LKGHT V V T
Sbjct: 112 VMELHYN-TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTG 170
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
S D T+++W++ + + V ++ + T D ++S D D+R +L
Sbjct: 171 SDDGTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTY 229
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK----EQSNVANFPGHV----GPV 387
+ + S+T +G + ++ V++WD++ ++ V F G+V +
Sbjct: 230 TMRGHAD-SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNL 288
Query: 388 TSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGT 447
S+S +G +A + D V +WD + + +I E+ F + A +
Sbjct: 289 LRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAG-SINEVAFHPDEPIIISASS 347
Query: 448 DVRVYL 453
D R+Y+
Sbjct: 348 DKRLYM 353
Score = 46.0 bits (104), Expect = 3e-04
Identities = 37/127 (29%), Positives = 60/127 (47%), Gaps = 5/127 (3%)
Query: 374 QSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL-RKLKNFKTIQLEENYAIKE 432
Q+ + GH G V F NG LA+A D + LW++ N+ T++ + A+ E
Sbjct: 56 QAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLK-GHSGAVME 114
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTASATG-VRFGKNAQYLASTSMDR 489
L ++ G+ L A TD V V+ + +K HT+ K+ Q + + S D
Sbjct: 115 LHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDDG 174
Query: 490 TLKLYGI 496
T+KL+ I
Sbjct: 175 TVKLWDI 181
>BC117246-1|AAI17247.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 392 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 449
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 450 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 506
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 507 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 562
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 563 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 620
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 621 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 652
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 510 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 567
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 568 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 625
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 626 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 659
>BC117244-1|AAI17245.1| 707|Homo sapiens F-box and WD repeat domain
containing 7 protein.
Length = 707
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 392 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 449
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 450 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 506
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 507 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 562
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 563 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 620
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 621 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 652
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 510 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 567
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 568 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 625
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 626 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 659
>AY049984-1|AAL07271.1| 707|Homo sapiens F-box protein CDC4
protein.
Length = 707
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 392 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 449
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 450 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 506
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 507 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 562
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 563 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 620
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 621 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 652
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 510 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 567
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 568 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 625
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 626 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 659
>AY033553-1|AAK57547.1| 627|Homo sapiens F-box protein FBW7
protein.
Length = 627
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 312 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 369
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 370 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 426
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 427 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 482
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 483 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 540
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 541 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 572
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 430 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 487
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 488 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 545
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 546 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 579
>AY008274-1|AAG16640.1| 589|Homo sapiens F-box protein SEL10
protein.
Length = 589
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 274 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 331
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 332 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 388
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 389 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 444
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 445 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 502
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 503 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 534
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 392 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 449
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 450 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 507
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 508 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 541
>AK223449-1|BAD97169.1| 627|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 627
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 312 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 369
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 370 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 426
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 427 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 482
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 483 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 540
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 541 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 572
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 430 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 487
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 488 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 545
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 546 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 579
>AK001933-1|BAA91986.1| 553|Homo sapiens protein ( Homo sapiens
cDNA FLJ11071 fis, clone PLACE1004937, moderately
similar to SEL-10 PROTEIN. ).
Length = 553
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 238 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 295
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 296 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 352
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 353 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 408
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 409 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 466
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 467 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 498
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 356 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 413
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 414 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 471
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 472 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 505
>AF411972-1|AAL06291.1| 627|Homo sapiens archipelago beta form
protein.
Length = 627
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 312 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 369
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 370 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 426
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 427 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 482
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 483 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 540
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 541 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 572
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 430 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 487
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 488 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 545
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 546 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 579
>AF411971-1|AAL06290.1| 707|Homo sapiens archipelago alpha form
protein.
Length = 707
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 392 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 449
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 450 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 506
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 507 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 562
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 563 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 620
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 621 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 652
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 510 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 567
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 568 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 625
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 626 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 659
>AF383178-1|AAK60269.1| 561|Homo sapiens F-box protein FBX30
protein.
Length = 561
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 246 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 303
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 304 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 360
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 361 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 416
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 417 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 474
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 475 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 506
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 364 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 421
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 422 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 479
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 480 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 513
>AF083383-1|AAC64084.1| 310|Homo sapiens 38kDa splicing factor
protein.
Length = 310
Score = 83.0 bits (196), Expect = 2e-15
Identities = 57/189 (30%), Positives = 86/189 (45%), Gaps = 4/189 (2%)
Query: 228 SKLLTGGNDRNATVFNKDTE-QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S L + G DR ++N + A LKGH+ V + Y+ D + +AS D T+ VW+
Sbjct: 20 STLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDS 79
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGVSL 345
T + L+ H V G ++ T SD DIR + + V
Sbjct: 80 ETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLA 139
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
T D +I G G +N +K+WDL++ GH VT +S S G YL + A D
Sbjct: 140 VTFNDTSDQIISG-GIDND-IKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMD 197
Query: 406 SCVKLWDLR 414
+ V++WD+R
Sbjct: 198 NTVRVWDVR 206
Score = 80.6 bits (190), Expect = 1e-14
Identities = 53/204 (25%), Positives = 100/204 (49%), Gaps = 5/204 (2%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSLHPT 310
+L GH +V +HP+ T+ +A D I +WNV A L+ H G V L +
Sbjct: 2 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD 61
Query: 311 GDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWD 370
G + S S+D+ A D TG+ + ++ + + + TG+++ VK+WD
Sbjct: 62 GSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWD 121
Query: 371 LKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAI 430
+++++ V F + V +++F++ + + D+ +K+WDLR+ K T++ + ++
Sbjct: 122 IRKKAAVQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHAD-SV 179
Query: 431 KELCFDQSGTYLAIAGTD--VRVY 452
L G+YL D VRV+
Sbjct: 180 TGLSLSSEGSYLLSNAMDNTVRVW 203
Score = 76.2 bits (179), Expect = 3e-13
Identities = 51/207 (24%), Positives = 89/207 (42%), Gaps = 7/207 (3%)
Query: 294 ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTG-QLLTKVSDFSGVSLTTAQFHP 352
+L H+G V HP G + S D+ ++ + SG ++ ++
Sbjct: 2 LLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSG-AVMELHYNT 60
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA-TAAEDSCVKLW 411
DG + + + + V +WD + V GH V S + G L T ++D VKLW
Sbjct: 61 DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLW 120
Query: 412 DLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAG--TDVRVYLCRQWQELKVFNDHTAS 469
D+RK +T Q Y + + F+ + + G D++V+ RQ + H S
Sbjct: 121 DIRKKAAVQTFQ--NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADS 178
Query: 470 ATGVRFGKNAQYLASTSMDRTLKLYGI 496
TG+ YL S +MD T++++ +
Sbjct: 179 VTGLSLSSEGSYLLSNAMDNTVRVWDV 205
Score = 58.0 bits (134), Expect = 7e-08
Identities = 40/146 (27%), Positives = 68/146 (46%), Gaps = 8/146 (5%)
Query: 232 TGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQT 291
TG +D +++ + V + +T +V V ++ D +I+ D+ I+VW++ ++
Sbjct: 110 TGSDDGTVKLWDIRKKAAVQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL 168
Query: 292 TAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTK-VSDFSG------VS 344
T +R H VTGLSL G Y+LS + D D+R + V F G +
Sbjct: 169 TYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKN 228
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWD 370
L + PDG G+ + V +WD
Sbjct: 229 LLRCSWSPDGSKIAAGSADRFVYVWD 254
Score = 56.0 bits (129), Expect = 3e-07
Identities = 47/205 (22%), Positives = 90/205 (43%), Gaps = 12/205 (5%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVI-YHPDEDTVITA 275
++ L N +D S L + D+ V++ +T + V LKGHT V V T
Sbjct: 53 VMELHYN-TDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTG 111
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
S D T+++W++ + + V ++ + T D ++S D D+R +L
Sbjct: 112 SDDGTVKLWDIRKKAAVQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTY 170
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK----EQSNVANFPGHV----GPV 387
+ + S+T +G + ++ V++WD++ ++ V F G+V +
Sbjct: 171 TMRGHAD-SVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNL 229
Query: 388 TSISFSENGYYLATAAEDSCVKLWD 412
S+S +G +A + D V +WD
Sbjct: 230 LRCSWSPDGSKIAAGSADRFVYVWD 254
>AB209725-1|BAD92962.1| 624|Homo sapiens F-box protein FBW7 isoform
2 variant protein.
Length = 624
Score = 83.0 bits (196), Expect = 2e-15
Identities = 67/274 (24%), Positives = 127/274 (46%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 309 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 366
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + ++
Sbjct: 367 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVLMGHV-AAVRC 423
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
Q+ DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 424 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 479
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 480 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 537
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 538 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 569
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 427 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 484
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 485 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 542
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 543 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 576
>BC106004-1|AAI06005.1| 514|Homo sapiens pleiotropic regulator 1
(PRL1 homolog, Arabidopsis) protein.
Length = 514
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/254 (23%), Positives = 111/254 (43%), Gaps = 14/254 (5%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H ++V G++ +P L + G D+ ++ + +V+ GH V + HP
Sbjct: 245 HISTVRGVIVSTRSPY----LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI 300
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
D ++T S D T R+W+V T + L H V + +++ S D D+
Sbjct: 301 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV 360
Query: 330 TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTS 389
G+ +++ S+ HP F +G+ ++ +K W + S + N GH + +
Sbjct: 361 AGKTRVTLTNHK-KSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINT 418
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI-------QLEENYAIKELCFDQSGTYL 442
++ + +G L + A++ + LWD R NF+ + L+ I FDQS + L
Sbjct: 419 LTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRL 477
Query: 443 AIAGTDVRVYLCRQ 456
A D + + R+
Sbjct: 478 LTAEADKTIKVYRE 491
Score = 68.5 bits (160), Expect = 5e-11
Identities = 35/162 (21%), Positives = 71/162 (43%), Gaps = 1/162 (0%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
++ GH V + P +T S D TI++W++ + + L H V G+ +
Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
Y+ S D+ D+ +++ ++ HP + T + +S +IWD+
Sbjct: 259 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLS-AVYGLDLHPTIDVLVTCSRDSTARIWDV 317
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
+ +++V GH V ++ + T + D+ ++LWDL
Sbjct: 318 RTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 359
Score = 63.3 bits (147), Expect = 2e-09
Identities = 41/181 (22%), Positives = 76/181 (41%), Gaps = 2/181 (1%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
+TG DR +++ + ++ L GH V VI + + D ++ W++ ++
Sbjct: 220 VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 279
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQF 350
H V GL LHPT D +++ S D D+RT + +S + T
Sbjct: 280 VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 339
Query: 351 HPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKL 410
+ I TG+ ++ +++WDL H V ++ Y A+ + D+ +K
Sbjct: 340 AAEPQII-TGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDN-IKQ 397
Query: 411 W 411
W
Sbjct: 398 W 398
Score = 49.2 bits (112), Expect = 3e-05
Identities = 37/147 (25%), Positives = 59/147 (40%), Gaps = 3/147 (2%)
Query: 352 PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
P F TG+ + +KIWDL + GH+ V + S YL + ED VK W
Sbjct: 214 PGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCW 273
Query: 412 DLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTAS 469
DL K + + A+ L + L D R++ R + + HT +
Sbjct: 274 DLEYNKVIRHYHGHLS-AVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNA 332
Query: 470 ATGVRFGKNAQYLASTSMDRTLKLYGI 496
VR + + S D T++L+ +
Sbjct: 333 VATVRCQAAEPQIITGSHDTTIRLWDL 359
>BC020786-1|AAH20786.1| 505|Homo sapiens PLRG1 protein protein.
Length = 505
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/254 (23%), Positives = 111/254 (43%), Gaps = 14/254 (5%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H ++V G++ +P L + G D+ ++ + +V+ GH V + HP
Sbjct: 236 HISTVRGVIVSTRSPY----LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI 291
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
D ++T S D T R+W+V T + L H V + +++ S D D+
Sbjct: 292 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV 351
Query: 330 TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTS 389
G+ +++ S+ HP F +G+ ++ +K W + S + N GH + +
Sbjct: 352 AGKTRVTLTNHK-KSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINT 409
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI-------QLEENYAIKELCFDQSGTYL 442
++ + +G L + A++ + LWD R NF+ + L+ I FDQS + L
Sbjct: 410 LTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRL 468
Query: 443 AIAGTDVRVYLCRQ 456
A D + + R+
Sbjct: 469 LTAEADKTIKVYRE 482
Score = 68.5 bits (160), Expect = 5e-11
Identities = 35/162 (21%), Positives = 71/162 (43%), Gaps = 1/162 (0%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
++ GH V + P +T S D TI++W++ + + L H V G+ +
Sbjct: 190 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 249
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
Y+ S D+ D+ +++ ++ HP + T + +S +IWD+
Sbjct: 250 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLS-AVYGLDLHPTIDVLVTCSRDSTARIWDV 308
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
+ +++V GH V ++ + T + D+ ++LWDL
Sbjct: 309 RTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 350
Score = 63.3 bits (147), Expect = 2e-09
Identities = 41/181 (22%), Positives = 76/181 (41%), Gaps = 2/181 (1%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
+TG DR +++ + ++ L GH V VI + + D ++ W++ ++
Sbjct: 211 VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 270
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQF 350
H V GL LHPT D +++ S D D+RT + +S + T
Sbjct: 271 VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 330
Query: 351 HPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKL 410
+ I TG+ ++ +++WDL H V ++ Y A+ + D+ +K
Sbjct: 331 AAEPQII-TGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDN-IKQ 388
Query: 411 W 411
W
Sbjct: 389 W 389
Score = 49.2 bits (112), Expect = 3e-05
Identities = 37/147 (25%), Positives = 59/147 (40%), Gaps = 3/147 (2%)
Query: 352 PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
P F TG+ + +KIWDL + GH+ V + S YL + ED VK W
Sbjct: 205 PGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCW 264
Query: 412 DLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTAS 469
DL K + + A+ L + L D R++ R + + HT +
Sbjct: 265 DLEYNKVIRHYHGHLS-AVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNA 323
Query: 470 ATGVRFGKNAQYLASTSMDRTLKLYGI 496
VR + + S D T++L+ +
Sbjct: 324 VATVRCQAAEPQIITGSHDTTIRLWDL 350
>AF044333-1|AAD09407.1| 514|Homo sapiens pleiotropic regulator 1
protein.
Length = 514
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/254 (23%), Positives = 111/254 (43%), Gaps = 14/254 (5%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H ++V G++ +P L + G D+ ++ + +V+ GH V + HP
Sbjct: 245 HISTVRGVIVSTRSPY----LFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI 300
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
D ++T S D T R+W+V T + L H V + +++ S D D+
Sbjct: 301 DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV 360
Query: 330 TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTS 389
G+ +++ S+ HP F +G+ ++ +K W + S + N GH + +
Sbjct: 361 AGKTRVTLTNHK-KSVRAVVLHPRHYTFASGSPDN-IKQWKFPDGSFIQNLSGHNAIINT 418
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI-------QLEENYAIKELCFDQSGTYL 442
++ + +G L + A++ + LWD R NF+ + L+ I FDQS + L
Sbjct: 419 LTVNSDG-VLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRL 477
Query: 443 AIAGTDVRVYLCRQ 456
A D + + R+
Sbjct: 478 LTAEADKTIKVYRE 491
Score = 68.5 bits (160), Expect = 5e-11
Identities = 35/162 (21%), Positives = 71/162 (43%), Gaps = 1/162 (0%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
++ GH V + P +T S D TI++W++ + + L H V G+ +
Sbjct: 199 VISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRS 258
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
Y+ S D+ D+ +++ ++ HP + T + +S +IWD+
Sbjct: 259 PYLFSCGEDKQVKCWDLEYNKVIRHYHGHLS-AVYGLDLHPTIDVLVTCSRDSTARIWDV 317
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
+ +++V GH V ++ + T + D+ ++LWDL
Sbjct: 318 RTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDL 359
Score = 63.3 bits (147), Expect = 2e-09
Identities = 41/181 (22%), Positives = 76/181 (41%), Gaps = 2/181 (1%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQ 290
+TG DR +++ + ++ L GH V VI + + D ++ W++ ++
Sbjct: 220 VTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNK 279
Query: 291 TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQF 350
H V GL LHPT D +++ S D D+RT + +S + T
Sbjct: 280 VIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQ 339
Query: 351 HPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKL 410
+ I TG+ ++ +++WDL H V ++ Y A+ + D+ +K
Sbjct: 340 AAEPQII-TGSHDTTIRLWDLVAGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDN-IKQ 397
Query: 411 W 411
W
Sbjct: 398 W 398
Score = 49.2 bits (112), Expect = 3e-05
Identities = 37/147 (25%), Positives = 59/147 (40%), Gaps = 3/147 (2%)
Query: 352 PDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
P F TG+ + +KIWDL + GH+ V + S YL + ED VK W
Sbjct: 214 PGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCW 273
Query: 412 DLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTAS 469
DL K + + A+ L + L D R++ R + + HT +
Sbjct: 274 DLEYNKVIRHYHGHLS-AVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNA 332
Query: 470 ATGVRFGKNAQYLASTSMDRTLKLYGI 496
VR + + S D T++L+ +
Sbjct: 333 VATVRCQAAEPQIITGSHDTTIRLWDL 359
>BC068499-1|AAH68499.1| 351|Homo sapiens THO complex 3 protein.
Length = 351
Score = 82.2 bits (194), Expect = 4e-15
Identities = 59/226 (26%), Positives = 100/226 (44%), Gaps = 7/226 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAI--LKGHTKKVTRVIYHPDE-DTVITASPDHTIR 282
D +L +G D+ A+VF + +++V +GH V ++ +HP D +TAS D TIR
Sbjct: 66 DGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIR 125
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+W+V T++ A + + G + P G + + D F D +T + +K +
Sbjct: 126 IWDVRTTKCIATVNTK-GENINICWSPDGQTIAVGNKDDVVTFIDAKTHR--SKAEEQFK 182
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATA 402
+ ++ D +F N + I E V + H I F G Y AT
Sbjct: 183 FEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATG 242
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+ D+ V LWD+ +L + ++ ++ L F G LA A D
Sbjct: 243 SADALVSLWDVDELVCVRCFS-RLDWPVRTLSFSHDGKMLASASED 287
Score = 50.0 bits (114), Expect = 2e-05
Identities = 43/205 (20%), Positives = 88/205 (42%), Gaps = 7/205 (3%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
+PS+ +T D+ +++ T + +A + + + + + PD T+ + D +
Sbjct: 108 HPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVT 166
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+ T ++ A V +S + + T+ + +I + L V +
Sbjct: 167 FIDAKTHRSKAE-EQFKFEVNEISWNNDNNMFFLTNGN---GCINILSYPELKPVQSINA 222
Query: 343 --VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+ +F P G F TG+ ++ V +WD+ E V F PV ++SFS +G LA
Sbjct: 223 HPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLA 282
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLE 425
+A+ED + + ++ +Q E
Sbjct: 283 SASEDHFIDIAEVETGDKLWEVQCE 307
Score = 38.7 bits (86), Expect = 0.047
Identities = 30/159 (18%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Query: 342 GVSLTTAQFHPDGL-IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
G S+ +HP +F T + + ++IWD++ +A G +I +S +G +A
Sbjct: 99 GDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATV-NTKGENINICWSPDGQTIA 157
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCF--DQSGTYLAIAGTDVRVYLCRQWQ 458
+D V D + ++ Q + + + E+ + D + +L + + + +
Sbjct: 158 VGNKDDVVTFIDAKTHRSKAEEQFK--FEVNEISWNNDNNMFFLTNGNGCINILSYPELK 215
Query: 459 ELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++ N H ++ ++F +Y A+ S D + L+ ++
Sbjct: 216 PVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVD 254
Score = 35.1 bits (77), Expect = 0.57
Identities = 35/158 (22%), Positives = 56/158 (35%), Gaps = 3/158 (1%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
N ++ LT GN + + + V +I H + + P T S D +
Sbjct: 191 NNDNNMFFLTNGNGCINILSYPELKPVQSI-NAHPSNCICIKFDPMGKYFATGSADALVS 249
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+W+V D PV LS G + S S D +++ TG L +V S
Sbjct: 250 LWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCES- 308
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANF 380
T +HP + ++ K +E V F
Sbjct: 309 -PTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLF 345
>BC066325-1|AAH66325.1| 327|Homo sapiens THOC3 protein protein.
Length = 327
Score = 82.2 bits (194), Expect = 4e-15
Identities = 59/226 (26%), Positives = 100/226 (44%), Gaps = 7/226 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAI--LKGHTKKVTRVIYHPDE-DTVITASPDHTIR 282
D +L +G D+ A+VF + +++V +GH V ++ +HP D +TAS D TIR
Sbjct: 66 DGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIR 125
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+W+V T++ A + + G + P G + + D F D +T + +K +
Sbjct: 126 IWDVRTTKCIATVNTK-GENINICWSPDGQTIAVGNKDDVVTFIDAKTHR--SKAEEQFK 182
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATA 402
+ ++ D +F N + I E V + H I F G Y AT
Sbjct: 183 FEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATG 242
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+ D+ V LWD+ +L + ++ ++ L F G LA A D
Sbjct: 243 SADALVSLWDVDELVCVRCFS-RLDWPVRTLSFSHDGKMLASASED 287
Score = 49.6 bits (113), Expect = 2e-05
Identities = 44/202 (21%), Positives = 89/202 (44%), Gaps = 8/202 (3%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
+PS+ +T D+ +++ T + +A + + + + + PD T+ + D +
Sbjct: 108 HPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVT 166
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+ T ++ A V +S + + T+ + +I + L V +
Sbjct: 167 FIDAKTHRSKAE-EQFKFEVNEISWNNDNNMFFLTNGN---GCINILSYPELKPVQSINA 222
Query: 343 --VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+ +F P G F TG+ ++ V +WD+ E V F PV ++SFS +G LA
Sbjct: 223 HPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLA 282
Query: 401 TAAEDSCVKLWDLRKLKNFKTI 422
+A+ED + + ++ + NF I
Sbjct: 283 SASEDHFIDIAEV-ETGNFMRI 303
Score = 38.7 bits (86), Expect = 0.047
Identities = 30/159 (18%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Query: 342 GVSLTTAQFHPDGL-IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
G S+ +HP +F T + + ++IWD++ +A G +I +S +G +A
Sbjct: 99 GDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATV-NTKGENINICWSPDGQTIA 157
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCF--DQSGTYLAIAGTDVRVYLCRQWQ 458
+D V D + ++ Q + + + E+ + D + +L + + + +
Sbjct: 158 VGNKDDVVTFIDAKTHRSKAEEQFK--FEVNEISWNNDNNMFFLTNGNGCINILSYPELK 215
Query: 459 ELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++ N H ++ ++F +Y A+ S D + L+ ++
Sbjct: 216 PVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVD 254
>BC006849-1|AAH06849.1| 351|Homo sapiens THO complex 3 protein.
Length = 351
Score = 82.2 bits (194), Expect = 4e-15
Identities = 59/226 (26%), Positives = 100/226 (44%), Gaps = 7/226 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAI--LKGHTKKVTRVIYHPDE-DTVITASPDHTIR 282
D +L +G D+ A+VF + +++V +GH V ++ +HP D +TAS D TIR
Sbjct: 66 DGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIR 125
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+W+V T++ A + + G + P G + + D F D +T + +K +
Sbjct: 126 IWDVRTTKCIATVNTK-GENINICWSPDGQTIAVGNKDDVVTFIDAKTHR--SKAEEQFK 182
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATA 402
+ ++ D +F N + I E V + H I F G Y AT
Sbjct: 183 FEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATG 242
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
+ D+ V LWD+ +L + ++ ++ L F G LA A D
Sbjct: 243 SADALVSLWDVDELVCVRCFS-RLDWPVRTLSFSHDGKMLASASED 287
Score = 50.0 bits (114), Expect = 2e-05
Identities = 43/205 (20%), Positives = 88/205 (42%), Gaps = 7/205 (3%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
+PS+ +T D+ +++ T + +A + + + + + PD T+ + D +
Sbjct: 108 HPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENIN-ICWSPDGQTIAVGNKDDVVT 166
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+ T ++ A V +S + + T+ + +I + L V +
Sbjct: 167 FIDAKTHRSKAE-EQFKFEVNEISWNNDNNMFFLTNGN---GCINILSYPELKPVQSINA 222
Query: 343 --VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+ +F P G F TG+ ++ V +WD+ E V F PV ++SFS +G LA
Sbjct: 223 HPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLA 282
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLE 425
+A+ED + + ++ +Q E
Sbjct: 283 SASEDHFIDIAEVETGDKLWEVQCE 307
Score = 38.7 bits (86), Expect = 0.047
Identities = 30/159 (18%), Positives = 71/159 (44%), Gaps = 6/159 (3%)
Query: 342 GVSLTTAQFHPDGL-IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
G S+ +HP +F T + + ++IWD++ +A G +I +S +G +A
Sbjct: 99 GDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATV-NTKGENINICWSPDGQTIA 157
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCF--DQSGTYLAIAGTDVRVYLCRQWQ 458
+D V D + ++ Q + + + E+ + D + +L + + + +
Sbjct: 158 VGNKDDVVTFIDAKTHRSKAEEQFK--FEVNEISWNNDNNMFFLTNGNGCINILSYPELK 215
Query: 459 ELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++ N H ++ ++F +Y A+ S D + L+ ++
Sbjct: 216 PVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVD 254
Score = 35.1 bits (77), Expect = 0.57
Identities = 35/158 (22%), Positives = 56/158 (35%), Gaps = 3/158 (1%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
N ++ LT GN + + + V +I H + + P T S D +
Sbjct: 191 NNDNNMFFLTNGNGCINILSYPELKPVQSI-NAHPSNCICIKFDPMGKYFATGSADALVS 249
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+W+V D PV LS G + S S D +++ TG L +V S
Sbjct: 250 LWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCES- 308
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANF 380
T +HP + ++ K +E V F
Sbjct: 309 -PTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLF 345
>BC037320-1|AAH37320.1| 621|Homo sapiens FBXW7 protein protein.
Length = 621
Score = 81.8 bits (193), Expect = 5e-15
Identities = 67/274 (24%), Positives = 124/274 (45%), Gaps = 17/274 (6%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
+++++G +D V++ T + + L GHT V ++ +I+ S D T++VWN
Sbjct: 306 NRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAE 363
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
T + L H V + LH V+S S D DI TGQ L + G
Sbjct: 364 TGECIHTLYGHTSTVRCMHLHE--KRVVSGSRDATLRVWDIETGQCLHVL---MGHVAAV 418
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSC 407
DG +G + VK+WD + ++ + GH V S+ F +G ++ + + D+
Sbjct: 419 RCVRYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTS 476
Query: 408 VKLWDLRKLKNFKTI----QLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVF 463
+++WD+ T+ L +K+ + D++ C Q L+
Sbjct: 477 IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQC--LQTLQGP 534
Query: 464 NDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
N H ++ T ++F KN ++ ++S D T+KL+ ++
Sbjct: 535 NKHQSAVTCLQFNKN--FVITSSDDGTVKLWDLK 566
Score = 65.7 bits (153), Expect = 4e-10
Identities = 45/156 (28%), Positives = 81/156 (51%), Gaps = 8/156 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++G D V++ +TE + L+GHT +V + + D V++ S D +IRVW+
Sbjct: 424 DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWD 481
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGV 343
V T L H +G+ L + ++S ++D DI+TGQ L + +
Sbjct: 482 VETGNCIHTLTGHQSLTSGMEL--KDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQS 539
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVAN 379
++T QF+ + +I T +++ VK+WDLK + N
Sbjct: 540 AVTCLQFNKNFVI--TSSDDGTVKLWDLKTGEFIRN 573
>X95263-1|CAA64560.1| 919|Homo sapiens PWP2 protein.
Length = 919
Score = 81.4 bits (192), Expect = 7e-15
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 7/246 (2%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
+G +T +H ++T + +P L D + ++++ +GD+
Sbjct: 285 EGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDW 344
Query: 314 VLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S Q + +L + F+ S+ + PDG TG ++ +VK+W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFN--SMVALAYSPDGQYIVTGGDDGKVKVWNT 402
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
F H VT ++F+ GY + T++ D V+ +DL + +NF+T
Sbjct: 403 LSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFS 462
Query: 432 ELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ D SG ++ D + V+ + + L V + H +G+ F LAS S D
Sbjct: 463 CVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWD 522
Query: 489 RTLKLY 494
+T++L+
Sbjct: 523 KTVRLW 528
Score = 74.1 bits (174), Expect = 1e-12
Identities = 49/208 (23%), Positives = 87/208 (41%), Gaps = 3/208 (1%)
Query: 209 LHSASVP--GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH 266
+HS S+ I S+ IN S V+ +E V +GH + + Y
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
PD ++T D ++VWN + H VTG++ TG V+++S D
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS-QVKIWDLKEQSNVANFPGHVG 385
D+ + + + G I G ++S ++ +W ++ + GH G
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEG 502
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDL 413
P++ + F+ LA+A+ D V+LWD+
Sbjct: 503 PISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 55.2 bits (127), Expect = 5e-07
Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 4/198 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 376 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 434
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 435 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 494
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
+S G ++ F+P + + + + V++WD+ + +++F
Sbjct: 495 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRP 553
Query: 395 NGYYLATAAEDSCVKLWD 412
+G LA A +S + WD
Sbjct: 554 DGAELAVATLNSQITFWD 571
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 275 ASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---W-AFSDIRT 330
A I VW++ T + +L H+GP++GL +P + S S D+ W F RT
Sbjct: 477 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 536
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ L SD V+ F PDG T NSQ+ WD + + G
Sbjct: 537 KETLALTSDALAVT-----FRPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
K DF+ +LT A FH + TG + + +L E + + + + S++ + +
Sbjct: 284 KEGDFN--NLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSS 341
Query: 396 GYYLATAAED-SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLC 454
G ++A + +W+ + +++ Q ++ L + G Y+ G D +V
Sbjct: 342 GDWIAFGCSGLGQLLVWEWQS-ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKV--- 397
Query: 455 RQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ W L F +H++ TGV F + ++SMD T++ + +
Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
>U56089-1|AAC50905.1| 919|Homo sapiens periodic tryptophan protein
2 protein.
Length = 919
Score = 81.4 bits (192), Expect = 7e-15
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 7/246 (2%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
+G +T +H ++T + +P L D + ++++ +GD+
Sbjct: 285 EGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDW 344
Query: 314 VLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S Q + +L + F+ S+ + PDG TG ++ +VK+W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFN--SMVALAYSPDGQYIVTGGDDGKVKVWNT 402
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
F H VT ++F+ GY + T++ D V+ +DL + +NF+T
Sbjct: 403 LSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFS 462
Query: 432 ELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ D SG ++ D + V+ + + L V + H +G+ F LAS S D
Sbjct: 463 CVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWD 522
Query: 489 RTLKLY 494
+T++L+
Sbjct: 523 KTVRLW 528
Score = 74.1 bits (174), Expect = 1e-12
Identities = 49/208 (23%), Positives = 87/208 (41%), Gaps = 3/208 (1%)
Query: 209 LHSASVP--GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH 266
+HS S+ I S+ IN S V+ +E V +GH + + Y
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
PD ++T D ++VWN + H VTG++ TG V+++S D
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS-QVKIWDLKEQSNVANFPGHVG 385
D+ + + + G I G ++S ++ +W ++ + GH G
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEG 502
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDL 413
P++ + F+ LA+A+ D V+LWD+
Sbjct: 503 PISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 55.2 bits (127), Expect = 5e-07
Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 4/198 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 376 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 434
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 435 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 494
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
+S G ++ F+P + + + + V++WD+ + +++F
Sbjct: 495 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRP 553
Query: 395 NGYYLATAAEDSCVKLWD 412
+G LA A +S + WD
Sbjct: 554 DGAELAVATLNSQITFWD 571
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 275 ASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---W-AFSDIRT 330
A I VW++ T + +L H+GP++GL +P + S S D+ W F RT
Sbjct: 477 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 536
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ L SD V+ F PDG T NSQ+ WD + + G
Sbjct: 537 KETLALTSDALAVT-----FRPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
K DF+ +LT A FH + TG + + +L E + + + + S++ + +
Sbjct: 284 KEGDFN--NLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSS 341
Query: 396 GYYLATAAED-SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLC 454
G ++A + +W+ + +++ Q ++ L + G Y+ G D +V
Sbjct: 342 GDWIAFGCSGLGQLLVWEWQS-ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKV--- 397
Query: 455 RQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ W L F +H++ TGV F + ++SMD T++ + +
Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
>U56085-1|AAC50904.1| 919|Homo sapiens periodic tryptophan protein
2 protein.
Length = 919
Score = 81.4 bits (192), Expect = 7e-15
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 7/246 (2%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
+G +T +H ++T + +P L D + ++++ +GD+
Sbjct: 285 EGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDW 344
Query: 314 VLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S Q + +L + F+ S+ + PDG TG ++ +VK+W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFN--SMVALAYSPDGQYIVTGGDDGKVKVWNT 402
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
F H VT ++F+ GY + T++ D V+ +DL + +NF+T
Sbjct: 403 LSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFS 462
Query: 432 ELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ D SG ++ D + V+ + + L V + H +G+ F LAS S D
Sbjct: 463 CVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWD 522
Query: 489 RTLKLY 494
+T++L+
Sbjct: 523 KTVRLW 528
Score = 74.1 bits (174), Expect = 1e-12
Identities = 49/208 (23%), Positives = 87/208 (41%), Gaps = 3/208 (1%)
Query: 209 LHSASVP--GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH 266
+HS S+ I S+ IN S V+ +E V +GH + + Y
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
PD ++T D ++VWN + H VTG++ TG V+++S D
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS-QVKIWDLKEQSNVANFPGHVG 385
D+ + + + G I G ++S ++ +W ++ + GH G
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEG 502
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDL 413
P++ + F+ LA+A+ D V+LWD+
Sbjct: 503 PISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 55.2 bits (127), Expect = 5e-07
Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 4/198 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 376 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 434
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 435 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 494
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
+S G ++ F+P + + + + V++WD+ + +++F
Sbjct: 495 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRP 553
Query: 395 NGYYLATAAEDSCVKLWD 412
+G LA A +S + WD
Sbjct: 554 DGAELAVATLNSQITFWD 571
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 275 ASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---W-AFSDIRT 330
A I VW++ T + +L H+GP++GL +P + S S D+ W F RT
Sbjct: 477 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 536
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ L SD V+ F PDG T NSQ+ WD + + G
Sbjct: 537 KETLALTSDALAVT-----FRPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
K DF+ +LT A FH + TG + + +L E + + + + S++ + +
Sbjct: 284 KEGDFN--NLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSS 341
Query: 396 GYYLATAAED-SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLC 454
G ++A + +W+ + +++ Q ++ L + G Y+ G D +V
Sbjct: 342 GDWIAFGCSGLGQLLVWEWQS-ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKV--- 397
Query: 455 RQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ W L F +H++ TGV F + ++SMD T++ + +
Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
>U53346-1|AAB08084.1| 919|Homo sapiens PWP2H protein protein.
Length = 919
Score = 81.4 bits (192), Expect = 7e-15
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 7/246 (2%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
+G +T +H ++T + +P L D + ++++ +GD+
Sbjct: 285 EGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDW 344
Query: 314 VLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S Q + +L + F+ S+ + PDG TG ++ +VK+W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFN--SMVALAYSPDGQYIVTGGDDGKVKVWNT 402
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
F H VT ++F+ GY + T++ D V+ +DL + +NF+T
Sbjct: 403 LSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFS 462
Query: 432 ELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ D SG ++ D + V+ + + L V + H +G+ F LAS S D
Sbjct: 463 CVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWD 522
Query: 489 RTLKLY 494
+T++L+
Sbjct: 523 KTVRLW 528
Score = 74.1 bits (174), Expect = 1e-12
Identities = 49/208 (23%), Positives = 87/208 (41%), Gaps = 3/208 (1%)
Query: 209 LHSASVP--GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH 266
+HS S+ I S+ IN S V+ +E V +GH + + Y
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
PD ++T D ++VWN + H VTG++ TG V+++S D
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS-QVKIWDLKEQSNVANFPGHVG 385
D+ + + + G I G ++S ++ +W ++ + GH G
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEG 502
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDL 413
P++ + F+ LA+A+ D V+LWD+
Sbjct: 503 PISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 55.2 bits (127), Expect = 5e-07
Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 4/198 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 376 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 434
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 435 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 494
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
+S G ++ F+P + + + + V++WD+ + +++F
Sbjct: 495 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRP 553
Query: 395 NGYYLATAAEDSCVKLWD 412
+G LA A +S + WD
Sbjct: 554 DGAELAVATLNSQITFWD 571
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 275 ASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---W-AFSDIRT 330
A I VW++ T + +L H+GP++GL +P + S S D+ W F RT
Sbjct: 477 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 536
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ L SD V+ F PDG T NSQ+ WD + + G
Sbjct: 537 KETLALTSDALAVT-----FRPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
K DF+ +LT A FH + TG + + +L E + + + + S++ + +
Sbjct: 284 KEGDFN--NLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSS 341
Query: 396 GYYLATAAED-SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLC 454
G ++A + +W+ + +++ Q ++ L + G Y+ G D +V
Sbjct: 342 GDWIAFGCSGLGQLLVWEWQS-ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKV--- 397
Query: 455 RQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ W L F +H++ TGV F + ++SMD T++ + +
Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
>BC031227-1|AAH31227.2| 452|Homo sapiens WDR88 protein protein.
Length = 452
Score = 81.4 bits (192), Expect = 7e-15
Identities = 61/256 (23%), Positives = 114/256 (44%), Gaps = 13/256 (5%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN-VPTSQTTAILRSHDGPVTGLSLHPT 310
IL GH V+ + D+ +++ S D T+++W+ V S PV S+
Sbjct: 123 ILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGD 182
Query: 311 GDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTE-NSQVKIW 369
V++ S D+ D+ TG+LL KV + + +F PDG +G + + + I
Sbjct: 183 SSRVIAASYDKTVRAWDLETGKLLWKVR--YDTFIVSCKFSPDGKYVVSGFDVDHGICIM 240
Query: 370 DLKEQSNVANFPGH-VGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENY 428
D + + V+ H +TS F + +A+ + D C+K+WD+ TI +
Sbjct: 241 DAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSN 300
Query: 429 AIKELCFDQSGTYLAIAGTDVRVYLCR----QWQE----LKVFNDHTASATGVRFGKNAQ 480
AI CF SG +L + D + + +++ + + H S + F +++
Sbjct: 301 AISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGACVTLMQGHEGSVSSCHFARDSS 360
Query: 481 YLASTSMDRTLKLYGI 496
+L S DRT+ ++ +
Sbjct: 361 FLISGGFDRTVAIWDV 376
Score = 77.0 bits (181), Expect = 1e-13
Identities = 50/203 (24%), Positives = 100/203 (49%), Gaps = 13/203 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQV--VAILKGH-TKKVTRVIYHPDEDTVITASPDHTI 281
S K + G D + + D E + V+++K H T+ +T + PD V + S D I
Sbjct: 221 SPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCI 280
Query: 282 RVWNVPTSQTT--AILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQL------ 333
++W+V TSQ T I ++H ++ +G ++ ++S D++ ++ TG+
Sbjct: 281 KIWDV-TSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNCGAC 339
Query: 334 LTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
+T + G S+++ F D +G + V IWD+ E + GH V ++ S
Sbjct: 340 VTLMQGHEG-SVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAIS 398
Query: 394 ENGYYLATAAEDSCVKLWDLRKL 416
N ++ +A++D ++LW++ ++
Sbjct: 399 NNKKWILSASKDRTMRLWNIEEI 421
>BC014988-1|AAH14988.1| 919|Homo sapiens PWP2 periodic tryptophan
protein homolog (yeast) protein.
Length = 919
Score = 81.4 bits (192), Expect = 7e-15
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 7/246 (2%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
+G +T +H ++T + +P L D + ++++ +GD+
Sbjct: 285 EGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDW 344
Query: 314 VLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S Q + +L + F+ S+ + PDG TG ++ +VK+W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFN--SMVALAYSPDGQYIVTGGDDGKVKVWNT 402
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
F H VT ++F+ GY + T++ D V+ +DL + +NF+T
Sbjct: 403 LSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFS 462
Query: 432 ELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ D SG ++ D + V+ + + L V + H +G+ F LAS S D
Sbjct: 463 CVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWD 522
Query: 489 RTLKLY 494
+T++L+
Sbjct: 523 KTVRLW 528
Score = 74.1 bits (174), Expect = 1e-12
Identities = 49/208 (23%), Positives = 87/208 (41%), Gaps = 3/208 (1%)
Query: 209 LHSASVP--GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH 266
+HS S+ I S+ IN S V+ +E V +GH + + Y
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
PD ++T D ++VWN + H VTG++ TG V+++S D
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS-QVKIWDLKEQSNVANFPGHVG 385
D+ + + + G I G ++S ++ +W ++ + GH G
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEG 502
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDL 413
P++ + F+ LA+A+ D V+LWD+
Sbjct: 503 PISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 52.8 bits (121), Expect = 3e-06
Identities = 42/198 (21%), Positives = 89/198 (44%), Gaps = 4/198 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 376 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 434
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 435 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 494
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
+S G ++ F+P + + + + V++WD+ + +++
Sbjct: 495 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTIRP 553
Query: 395 NGYYLATAAEDSCVKLWD 412
+G LA A +S + WD
Sbjct: 554 DGAELAVATLNSQITFWD 571
Score = 52.4 bits (120), Expect = 4e-06
Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 275 ASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---W-AFSDIRT 330
A I VW++ T + +L H+GP++GL +P + S S D+ W F RT
Sbjct: 477 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 536
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ L SD V++ PDG T NSQ+ WD + + G
Sbjct: 537 KETLALTSDALAVTI-----RPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
K DF+ +LT A FH + TG + + +L E + + + + S++ + +
Sbjct: 284 KEGDFN--NLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSS 341
Query: 396 GYYLATAAED-SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLC 454
G ++A + +W+ + +++ Q ++ L + G Y+ G D +V
Sbjct: 342 GDWIAFGCSGLGQLLVWEWQS-ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKV--- 397
Query: 455 RQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ W L F +H++ TGV F + ++SMD T++ + +
Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
>BC013309-1|AAH13309.1| 919|Homo sapiens PWP2 periodic tryptophan
protein homolog (yeast) protein.
Length = 919
Score = 81.4 bits (192), Expect = 7e-15
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 7/246 (2%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
+G +T +H ++T + +P L D + ++++ +GD+
Sbjct: 285 EGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDW 344
Query: 314 VLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S Q + +L + F+ S+ + PDG TG ++ +VK+W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFN--SMVALAYSPDGQYIVTGGDDGKVKVWNT 402
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
F H VT ++F+ GY + T++ D V+ +DL + +NF+T
Sbjct: 403 LSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFS 462
Query: 432 ELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ D SG ++ D + V+ + + L V + H +G+ F LAS S D
Sbjct: 463 CVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWD 522
Query: 489 RTLKLY 494
+T++L+
Sbjct: 523 KTVRLW 528
Score = 74.1 bits (174), Expect = 1e-12
Identities = 49/208 (23%), Positives = 87/208 (41%), Gaps = 3/208 (1%)
Query: 209 LHSASVP--GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH 266
+HS S+ I S+ IN S V+ +E V +GH + + Y
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
PD ++T D ++VWN + H VTG++ TG V+++S D
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS-QVKIWDLKEQSNVANFPGHVG 385
D+ + + + G I G ++S ++ +W ++ + GH G
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEG 502
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDL 413
P++ + F+ LA+A+ D V+LWD+
Sbjct: 503 PISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 52.8 bits (121), Expect = 3e-06
Identities = 42/198 (21%), Positives = 89/198 (44%), Gaps = 4/198 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 376 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 434
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 435 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 494
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
+S G ++ F+P + + + + V++WD+ + +++
Sbjct: 495 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTIRP 553
Query: 395 NGYYLATAAEDSCVKLWD 412
+G LA A +S + WD
Sbjct: 554 DGAELAVATLNSQITFWD 571
Score = 52.4 bits (120), Expect = 4e-06
Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 275 ASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---W-AFSDIRT 330
A I VW++ T + +L H+GP++GL +P + S S D+ W F RT
Sbjct: 477 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 536
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ L SD V++ PDG T NSQ+ WD + + G
Sbjct: 537 KETLALTSDALAVTI-----RPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
K DF+ +LT A FH + TG + + +L E + + + + S++ + +
Sbjct: 284 KEGDFN--NLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSS 341
Query: 396 GYYLATAAED-SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLC 454
G ++A + +W+ + +++ Q ++ L + G Y+ G D +V
Sbjct: 342 GDWIAFGCSGLGQLLVWEWQS-ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKV--- 397
Query: 455 RQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ W L F +H++ TGV F + ++SMD T++ + +
Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
>AP001753-1|BAA95553.1| 919|Homo sapiens periodic tryptophan
protein 2 homolog protein.
Length = 919
Score = 81.4 bits (192), Expect = 7e-15
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 7/246 (2%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
+G +T +H ++T + +P L D + ++++ +GD+
Sbjct: 285 EGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDW 344
Query: 314 VLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S Q + +L + F+ S+ + PDG TG ++ +VK+W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFN--SMVALAYSPDGQYIVTGGDDGKVKVWNT 402
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
F H VT ++F+ GY + T++ D V+ +DL + +NF+T
Sbjct: 403 LSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFS 462
Query: 432 ELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ D SG ++ D + V+ + + L V + H +G+ F LAS S D
Sbjct: 463 CVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWD 522
Query: 489 RTLKLY 494
+T++L+
Sbjct: 523 KTVRLW 528
Score = 74.1 bits (174), Expect = 1e-12
Identities = 49/208 (23%), Positives = 87/208 (41%), Gaps = 3/208 (1%)
Query: 209 LHSASVP--GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH 266
+HS S+ I S+ IN S V+ +E V +GH + + Y
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
PD ++T D ++VWN + H VTG++ TG V+++S D
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS-QVKIWDLKEQSNVANFPGHVG 385
D+ + + + G I G ++S ++ +W ++ + GH G
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEG 502
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDL 413
P++ + F+ LA+A+ D V+LWD+
Sbjct: 503 PISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 55.2 bits (127), Expect = 5e-07
Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 4/198 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 376 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 434
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 435 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 494
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
+S G ++ F+P + + + + V++WD+ + +++F
Sbjct: 495 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRP 553
Query: 395 NGYYLATAAEDSCVKLWD 412
+G LA A +S + WD
Sbjct: 554 DGAELAVATLNSQITFWD 571
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 275 ASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---W-AFSDIRT 330
A I VW++ T + +L H+GP++GL +P + S S D+ W F RT
Sbjct: 477 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 536
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ L SD V+ F PDG T NSQ+ WD + + G
Sbjct: 537 KETLALTSDALAVT-----FRPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
K DF+ +LT A FH + TG + + +L E + + + + S++ + +
Sbjct: 284 KEGDFN--NLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSS 341
Query: 396 GYYLATAAED-SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLC 454
G ++A + +W+ + +++ Q ++ L + G Y+ G D +V
Sbjct: 342 GDWIAFGCSGLGQLLVWEWQS-ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKV--- 397
Query: 455 RQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ W L F +H++ TGV F + ++SMD T++ + +
Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
>AK131444-1|BAD18589.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ16579 fis, clone TESTI2049956, weakly similar
to Vegetatible incompatibility protein HET-E-1. ).
Length = 472
Score = 81.4 bits (192), Expect = 7e-15
Identities = 61/256 (23%), Positives = 114/256 (44%), Gaps = 13/256 (5%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN-VPTSQTTAILRSHDGPVTGLSLHPT 310
IL GH V+ + D+ +++ S D T+++W+ V S PV S+
Sbjct: 97 ILSGHEHAVSTCHFCVDDTKLLSGSYDCTVKLWDPVDGSVVRDFEHRPKAPVVECSITGD 156
Query: 311 GDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTE-NSQVKIW 369
V++ S D+ D+ TG+LL KV + + +F PDG +G + + + I
Sbjct: 157 SSRVIAASYDKTVRAWDLETGKLLWKVR--YDTFIVSCKFSPDGKYVVSGFDVDHGICIM 214
Query: 370 DLKEQSNVANFPGH-VGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENY 428
D + + V+ H +TS F + +A+ + D C+K+WD+ TI +
Sbjct: 215 DAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCIKIWDVTSQATLLTITKAHSN 274
Query: 429 AIKELCFDQSGTYLAIAGTDVRVYLCR----QWQE----LKVFNDHTASATGVRFGKNAQ 480
AI CF SG +L + D + + +++ + + H S + F +++
Sbjct: 275 AISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGACVTLMQGHEGSVSSCHFARDSS 334
Query: 481 YLASTSMDRTLKLYGI 496
+L S DRT+ ++ +
Sbjct: 335 FLISGGFDRTVAIWDV 350
Score = 77.0 bits (181), Expect = 1e-13
Identities = 50/203 (24%), Positives = 100/203 (49%), Gaps = 13/203 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQV--VAILKGH-TKKVTRVIYHPDEDTVITASPDHTI 281
S K + G D + + D E + V+++K H T+ +T + PD V + S D I
Sbjct: 195 SPDGKYVVSGFDVDHGICIMDAENITTVSVIKDHHTRSITSCCFDPDSQRVASVSLDRCI 254
Query: 282 RVWNVPTSQTT--AILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQL------ 333
++W+V TSQ T I ++H ++ +G ++ ++S D++ ++ TG+
Sbjct: 255 KIWDV-TSQATLLTITKAHSNAISNCCFTFSGHFLCTSSWDKNLKIWNVHTGEFRNRGAC 313
Query: 334 LTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS 393
+T + G S+++ F D +G + V IWD+ E + GH V ++ S
Sbjct: 314 VTLMQGHEG-SVSSCHFARDSSFLISGGFDRTVAIWDVAEGYRKLSLKGHNDWVMDVAIS 372
Query: 394 ENGYYLATAAEDSCVKLWDLRKL 416
N ++ +A++D ++LW++ ++
Sbjct: 373 NNKKWILSASKDRTMRLWNIEEI 395
>AB001517-2|BAA21137.1| 919|Homo sapiens PWP2 protein protein.
Length = 919
Score = 81.4 bits (192), Expect = 7e-15
Identities = 54/246 (21%), Positives = 105/246 (42%), Gaps = 7/246 (2%)
Query: 254 KGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDY 313
+G +T +H ++T + +P L D + ++++ +GD+
Sbjct: 285 EGDFNNLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDW 344
Query: 314 VLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+ S Q + +L + F+ S+ + PDG TG ++ +VK+W+
Sbjct: 345 IAFGCSGLGQLLVWEWQSESYVLKQQGHFN--SMVALAYSPDGQYIVTGGDDGKVKVWNT 402
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIK 431
F H VT ++F+ GY + T++ D V+ +DL + +NF+T
Sbjct: 403 LSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFS 462
Query: 432 ELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ D SG ++ D + V+ + + L V + H +G+ F LAS S D
Sbjct: 463 CVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWD 522
Query: 489 RTLKLY 494
+T++L+
Sbjct: 523 KTVRLW 528
Score = 74.1 bits (174), Expect = 1e-12
Identities = 49/208 (23%), Positives = 87/208 (41%), Gaps = 3/208 (1%)
Query: 209 LHSASVP--GILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYH 266
+HS S+ I S+ IN S V+ +E V +GH + + Y
Sbjct: 323 IHSLSISDQSIASVAINSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYS 382
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
PD ++T D ++VWN + H VTG++ TG V+++S D
Sbjct: 383 PDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAF 442
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS-QVKIWDLKEQSNVANFPGHVG 385
D+ + + + G I G ++S ++ +W ++ + GH G
Sbjct: 443 DLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEG 502
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDL 413
P++ + F+ LA+A+ D V+LWD+
Sbjct: 503 PISGLCFNPMKSVLASASWDKTVRLWDM 530
Score = 55.2 bits (127), Expect = 5e-07
Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 4/198 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 376 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 434
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 435 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 494
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSE 394
+S G ++ F+P + + + + V++WD+ + +++F
Sbjct: 495 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDMFDSWRTKETLALTSDALAVTFRP 553
Query: 395 NGYYLATAAEDSCVKLWD 412
+G LA A +S + WD
Sbjct: 554 DGAELAVATLNSQITFWD 571
Score = 54.0 bits (124), Expect = 1e-06
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 275 ASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---W-AFSDIRT 330
A I VW++ T + +L H+GP++GL +P + S S D+ W F RT
Sbjct: 477 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 536
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ L SD V+ F PDG T NSQ+ WD + + G
Sbjct: 537 KETLALTSDALAVT-----FRPDGAELAVATLNSQITFWDPENAVQTGSIEG 583
Score = 43.6 bits (98), Expect = 0.002
Identities = 35/167 (20%), Positives = 74/167 (44%), Gaps = 12/167 (7%)
Query: 336 KVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSEN 395
K DF+ +LT A FH + TG + + +L E + + + + S++ + +
Sbjct: 284 KEGDFN--NLTAAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSS 341
Query: 396 GYYLATAAED-SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLC 454
G ++A + +W+ + +++ Q ++ L + G Y+ G D +V
Sbjct: 342 GDWIAFGCSGLGQLLVWEWQS-ESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKV--- 397
Query: 455 RQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ W L F +H++ TGV F + ++SMD T++ + +
Sbjct: 398 KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
>AF208838-1|AAL34973.1| 410|Homo sapiens Miller-Dieker
lissencephaly protein protein.
Length = 410
Score = 81.0 bits (191), Expect = 9e-15
Identities = 64/291 (21%), Positives = 129/291 (44%), Gaps = 28/291 (9%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S +++ D V++ +T LKGHT V + + + + S D TI++ +
Sbjct: 121 SVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLRDFQ 180
Query: 288 TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTT 347
+ + HD V+ +++ P GD+++S S D+ +++TG V F+G
Sbjct: 181 GFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYC---VKTFTGHREWV 237
Query: 348 AQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFS-ENGY------- 397
P DG + + + + V++W + + A H V IS++ E+ Y
Sbjct: 238 RMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEAT 297
Query: 398 ------------YLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+L + + D +K+WD+ T+ +N+ ++ + F G ++
Sbjct: 298 GSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHDNW-VRGVLFHSGGKFILSC 356
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
D +RV+ + + +K N H T + F K A Y+ + S+D+T+K++
Sbjct: 357 ADDKTLRVWDYKNKRCMKTLNAHEHFVTSLDFHKTAPYVVTGSVDQTVKVW 407
Score = 78.6 bits (185), Expect = 5e-14
Identities = 46/193 (23%), Positives = 92/193 (47%), Gaps = 2/193 (1%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L GH VTRVI+HP +++AS D TI+VW+ T L+ H V +S +G
Sbjct: 104 LSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGK 163
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
+ S S+D D + + + + ++++ P+G + + + +K+W+++
Sbjct: 164 LLASCSADMTIKLRDFQGFECIRTMHGHDH-NVSSVAIMPNGDHIVSASRDKTIKMWEVQ 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
V F GH V + +++G +A+ + D V++W + K K E + ++
Sbjct: 223 TGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVW-VVATKECKAELREHEHVVEC 281
Query: 433 LCFDQSGTYLAIA 445
+ + +Y +I+
Sbjct: 282 ISWAPESSYSSIS 294
Score = 77.0 bits (181), Expect = 1e-13
Identities = 58/253 (22%), Positives = 111/253 (43%), Gaps = 24/253 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTE--QVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
DHS L + T+ +D + + + + GH V+ V P+ D +++AS D TI++
Sbjct: 159 DHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKM 218
Query: 284 WNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFS------DIRTGQLL 334
W V T H V + + G + S S+DQ W + ++R + +
Sbjct: 219 WEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHV 278
Query: 335 TKV------SDFSGVSLTTA----QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
+ S +S +S T + G +G+ + +K+WD+ + GH
Sbjct: 279 VECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTLVGHD 338
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V + F G ++ + A+D +++WD + + KT+ E++ + L F ++ Y+
Sbjct: 339 NWVRGVLFHSGGKFILSCADDKTLRVWDYKNKRCMKTLNAHEHF-VTSLDFHKTAPYVVT 397
Query: 445 AGTD--VRVYLCR 455
D V+V+ CR
Sbjct: 398 GSVDQTVKVWECR 410
Score = 60.5 bits (140), Expect = 1e-08
Identities = 35/152 (23%), Positives = 73/152 (48%), Gaps = 3/152 (1%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T FHP + + +E++ +K+WD + GH V ISF +G LA+ +
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSA 170
Query: 405 DSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKV 462
D +KL D + + +T+ ++ + + +G ++ A D ++++ + +K
Sbjct: 171 DMTIKLRDFQGFECIRTMH-GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229
Query: 463 FNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
F H VR ++ +AS S D+T++++
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVW 261
Score = 57.2 bits (132), Expect = 1e-07
Identities = 52/234 (22%), Positives = 97/234 (41%), Gaps = 26/234 (11%)
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+P L H PVT + HP ++S S D D TG + + S+
Sbjct: 95 IPRPPEKYALSGHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTD-SV 153
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
F G + + + + +K+ D + + GH V+S++ NG ++ +A+ D
Sbjct: 154 QDISFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD 213
Query: 406 SCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL---------- 453
+K+W+++ KT + ++ + +Q GT +A D VRV++
Sbjct: 214 KTIKMWEVQTGYCVKTFTGHREW-VRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAEL 272
Query: 454 --------CRQWQELKVFNDHTASATG---VRFGKNAQYLASTSMDRTLKLYGI 496
C W ++ + ATG + GK +L S S D+T+K++ +
Sbjct: 273 REHEHVVECISWAPESSYSS-ISEATGSETKKSGKPGPFLLSGSRDKTIKMWDV 325
>BT009800-1|AAP88802.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 80.2 bits (189), Expect = 2e-14
Identities = 43/188 (22%), Positives = 83/188 (44%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S + S
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICS 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 71.7 bits (168), Expect = 5e-12
Identities = 67/280 (23%), Positives = 119/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 124
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 183
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 184 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E +I + F SG L AG D + C W
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGR-LLFAGYD--DFNCNVWDS 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 300 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 68.1 bits (159), Expect = 7e-11
Identities = 58/237 (24%), Positives = 107/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + S T V F + + L
Sbjct: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLL 285
>BC002454-1|AAH02454.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 80.2 bits (189), Expect = 2e-14
Identities = 43/188 (22%), Positives = 83/188 (44%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S + S
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICS 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 71.7 bits (168), Expect = 5e-12
Identities = 67/280 (23%), Positives = 119/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 124
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 183
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 184 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E +I + F SG L AG D + C W
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGR-LLFAGYD--DFNCNVWDS 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 300 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 68.1 bits (159), Expect = 7e-11
Identities = 58/237 (24%), Positives = 107/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + S T V F + + L
Sbjct: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLL 285
>BC000115-1|AAH00115.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 80.2 bits (189), Expect = 2e-14
Identities = 43/188 (22%), Positives = 83/188 (44%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S + S
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICS 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 71.7 bits (168), Expect = 5e-12
Identities = 67/280 (23%), Positives = 119/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 124
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 183
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 184 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E +I + F SG L AG D + C W
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGR-LLFAGYD--DFNCNVWDS 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 300 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 68.1 bits (159), Expect = 7e-11
Identities = 58/237 (24%), Positives = 107/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + S T V F + + L
Sbjct: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLL 285
>Y12050-1|CAA72779.1| 340|Homo sapiens guanine nucleotide-binding
protein beta3 subunit protein.
Length = 340
Score = 78.6 bits (185), Expect = 5e-14
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S +
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 71.3 bits (167), Expect = 7e-12
Identities = 67/280 (23%), Positives = 118/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 124
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 183
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 184 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E I + F SG L AG D + C W
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGR-LLFAGYD--DFNCNVWDS 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 300 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 66.5 bits (155), Expect = 2e-10
Identities = 57/237 (24%), Positives = 106/237 (44%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + T V F + + L
Sbjct: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
>U47924-5|AAB51313.1| 340|Homo sapiens G-protein beta-3 chain
protein.
Length = 340
Score = 78.6 bits (185), Expect = 5e-14
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S +
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 71.3 bits (167), Expect = 7e-12
Identities = 67/280 (23%), Positives = 118/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 124
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 183
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 184 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E I + F SG L AG D + C W
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGR-LLFAGYD--DFNCNVWDS 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 300 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 66.5 bits (155), Expect = 2e-10
Identities = 57/237 (24%), Positives = 106/237 (44%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + T V F + + L
Sbjct: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
>M31328-1|AAA52582.1| 340|Homo sapiens GNB3 protein.
Length = 340
Score = 78.6 bits (185), Expect = 5e-14
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S +
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 71.3 bits (167), Expect = 7e-12
Identities = 67/280 (23%), Positives = 118/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 124
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 183
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 184 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E I + F SG L AG D + C W
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGR-LLFAGYD--DFNCNVWDS 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 300 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 66.5 bits (155), Expect = 2e-10
Identities = 57/237 (24%), Positives = 106/237 (44%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + T V F + + L
Sbjct: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
>AY631872-1|AAT38116.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 3 protein.
Length = 340
Score = 78.6 bits (185), Expect = 5e-14
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S +
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 71.3 bits (167), Expect = 7e-12
Identities = 67/280 (23%), Positives = 118/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 124
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 183
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 184 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E I + F SG L AG D + C W
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGR-LLFAGYD--DFNCNVWDS 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 300 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 66.5 bits (155), Expect = 2e-10
Identities = 57/237 (24%), Positives = 106/237 (44%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + T V F + + L
Sbjct: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
>AF501884-1|AAM15920.1| 340|Homo sapiens guanine nucleotide binding
protein beta 3 protein.
Length = 340
Score = 78.6 bits (185), Expect = 5e-14
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S +
Sbjct: 213 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 273 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 71.3 bits (167), Expect = 7e-12
Identities = 67/280 (23%), Positives = 118/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 124
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 125 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 183
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 184 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E I + F SG L AG D + C W
Sbjct: 243 TGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGR-LLFAGYD--DFNCNVWDS 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 300 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 339
Score = 66.5 bits (155), Expect = 2e-10
Identities = 57/237 (24%), Positives = 106/237 (44%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + T V F + + L
Sbjct: 229 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 285
>AB209283-1|BAD92520.1| 327|Homo sapiens guanine nucleotide-binding
protein, beta-3 subunit variant protein.
Length = 327
Score = 78.6 bits (185), Expect = 5e-14
Identities = 42/188 (22%), Positives = 82/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 140 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 199
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV-S 344
V H+ + + P G+ + + S D D+R Q L S S +
Sbjct: 200 VREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICG 259
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + V GH V+ + + +G +AT +
Sbjct: 260 ITSVAFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSW 319
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 320 DSFLKIWN 327
Score = 71.3 bits (167), Expect = 7e-12
Identities = 67/280 (23%), Positives = 118/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D V++ T V + + V Y P + V D+ ++
Sbjct: 52 TDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIY 111
Query: 285 NVPTSQ----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
N+ + + + L +H G ++ + V S S D A DI TGQ T
Sbjct: 112 NLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTS-SGDTTCALWDIETGQQKTVFVGH 170
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+G ++ A PD +F +G ++ K+WD++E + F GH + +I F NG +
Sbjct: 171 TGDCMSLA-VSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 229
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
T ++D+ +L+DLR + E I + F SG L AG D + C W
Sbjct: 230 TGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGR-LLFAGYD--DFNCNVWDS 286
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K + + H + + + +A+ S D LK++
Sbjct: 287 MKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFLKIW 326
Score = 66.5 bits (155), Expect = 2e-10
Identities = 57/237 (24%), Positives = 106/237 (44%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 38 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 97
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 98 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 156
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 157 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 215
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G + D R++ R QEL F+ + T V F + + L
Sbjct: 216 INAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLL 272
>X04526-2|CAA28207.1| 340|Homo sapiens protein ( Human liver mRNA
for beta-subunit signal transducing proteins Gs/Gi
(beta-G). ).
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>M36430-1|AAA63265.1| 247|Homo sapiens protein ( Human transducin
beta-1 subunit mRNA, 3' end. ).
Length = 247
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 60 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 119
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 120 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 179
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 180 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 239
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 240 DSFLKIWN 247
Score = 72.9 bits (171), Expect = 2e-12
Identities = 63/239 (26%), Positives = 105/239 (43%), Gaps = 13/239 (5%)
Query: 265 YHPDEDTVITASPDHTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQ 321
Y P + V D+ ++N+ T + + R G LS D ++++S D
Sbjct: 12 YAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDT 71
Query: 322 HWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFP 381
A DI TGQ T + +G + + PD +F +G ++ K+WD++E F
Sbjct: 72 TCALWDIETGQQTTTFTGHTG-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFT 130
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGT 440
GH + +I F NG AT ++D+ +L+DLR + T + I + F +SG
Sbjct: 131 GHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR 190
Query: 441 YLAIAGTDVRVYLCRQWQELK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
L +AG D + C W LK V H + + + +A+ S D LK++
Sbjct: 191 -LLLAGYD--DFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 246
>CR456784-1|CAG33065.1| 340|Homo sapiens GNB1 protein.
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BT007305-1|AAP35969.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BC008991-1|AAH08991.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BC005888-1|AAH05888.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BC004186-1|AAH04186.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>AL109917-5|CAI95654.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>AL031282-15|CAI20051.1| 197|Homo sapiens guanine nucleotide
binding protein (G protein), beta polypeptide 1 protein.
Length = 197
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 10 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 69
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 70 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 129
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 130 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 189
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 190 DSFLKIWN 197
Score = 70.9 bits (166), Expect = 9e-12
Identities = 52/187 (27%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKE 373
++++S D A DI TGQ T + +G + + PD +F +G ++ K+WD++E
Sbjct: 14 IVTSSGDTTCALWDIETGQQTTTFTGHTG-DVMSLSLAPDTRLFVSGACDASAKLWDVRE 72
Query: 374 QSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKE 432
F GH + +I F NG AT ++D+ +L+DLR + T + I
Sbjct: 73 GMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS 132
Query: 433 LCFDQSGTYLAIAGTDVRVYLCRQWQELK-----VFNDHTASATGVRFGKNAQYLASTSM 487
+ F +SG L +AG D + C W LK V H + + + +A+ S
Sbjct: 133 VSFSKSGR-LLLAGYD--DFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 189
Query: 488 DRTLKLY 494
D LK++
Sbjct: 190 DSFLKIW 196
>AL031282-2|CAI20029.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 1 protein.
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>AF501882-1|AAM15918.1| 340|Homo sapiens guanine nucleotide binding
protein beta 1 protein.
Length = 340
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 332
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 333 DSFLKIWN 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 69/279 (24%), Positives = 119/279 (42%), Gaps = 13/279 (4%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
K V H + + + +A+ S D LK++
Sbjct: 301 KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>AF070603-1|AAC28655.1| 207|Homo sapiens beta-subunit signal
transducing proteins GS/GI protein.
Length = 207
Score = 78.2 bits (184), Expect = 6e-14
Identities = 41/188 (21%), Positives = 81/188 (43%), Gaps = 1/188 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 20 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 79
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 80 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 139
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 140 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 199
Query: 405 DSCVKLWD 412
DS +K+W+
Sbjct: 200 DSFLKIWN 207
Score = 70.9 bits (166), Expect = 9e-12
Identities = 52/187 (27%), Positives = 87/187 (46%), Gaps = 10/187 (5%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKE 373
++++S D A DI TGQ T + +G + + PD +F +G ++ K+WD++E
Sbjct: 24 IVTSSGDTTCALWDIETGQQTTTFTGHTG-DVMSLSLAPDTRLFVSGACDASAKLWDVRE 82
Query: 374 QSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENY-AIKE 432
F GH + +I F NG AT ++D+ +L+DLR + T + I
Sbjct: 83 GMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS 142
Query: 433 LCFDQSGTYLAIAGTDVRVYLCRQWQELK-----VFNDHTASATGVRFGKNAQYLASTSM 487
+ F +SG L +AG D + C W LK V H + + + +A+ S
Sbjct: 143 VSFSKSGR-LLLAGYD--DFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSW 199
Query: 488 DRTLKLY 494
D LK++
Sbjct: 200 DSFLKIW 206
>M36429-1|AAA63264.1| 340|Homo sapiens protein ( Human transducin
beta-2 subunit mRNA, complete cds. ).
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + PD T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PDG F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 70.9 bits (166), Expect = 9e-12
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + +G + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>M16514-1|AAA03179.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + PD T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PDG F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 70.9 bits (166), Expect = 9e-12
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + +G + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>CR541729-1|CAG46530.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + PD T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PDG F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 70.9 bits (166), Expect = 9e-12
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + +G + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>BC114618-1|AAI14619.1| 332|Homo sapiens GNB1 protein protein.
Length = 332
Score = 77.8 bits (183), Expect = 8e-14
Identities = 59/237 (24%), Positives = 108/237 (45%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + +G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I +CF +G A D R++ R QEL ++ T V F K+ + L
Sbjct: 229 INAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLL 285
Score = 77.0 bits (181), Expect = 1e-13
Identities = 62/241 (25%), Positives = 105/241 (43%), Gaps = 8/241 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N+ T + + R G LS D ++++S D A DI TGQ T + +
Sbjct: 125 NLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHT 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PD +F +G ++ K+WD++E F GH + +I F NG AT
Sbjct: 185 G-DVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFAT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY-AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + T + I + F +SG L +AG D + C W L
Sbjct: 244 GSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGR-LLLAGYD--DFNCNVWDAL 300
Query: 461 K 461
K
Sbjct: 301 K 301
Score = 66.1 bits (154), Expect = 3e-10
Identities = 36/177 (20%), Positives = 73/177 (41%), Gaps = 1/177 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GHT V + PD ++ + D + ++W+
Sbjct: 153 DDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ-LLTKVSDFSGVS 344
V H+ + + P G+ + S D D+R Q L+T D
Sbjct: 213 VREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICG 272
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
+T+ F G + G ++ +WD + GH V+ + +++G +A+
Sbjct: 273 ITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVAS 329
Score = 32.7 bits (71), Expect = 3.1
Identities = 24/148 (16%), Positives = 59/148 (39%), Gaps = 4/148 (2%)
Query: 353 DGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
D + + +++ ++ IWD + V P V + +++ +G Y+A D+ +++
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 413 LRKLKNFKTI--QLEENYAIKELC--FDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTA 468
L+ + + +L + C D + + T ++ Q+ F HT
Sbjct: 126 LKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTG 185
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + + S + D + KL+ +
Sbjct: 186 DVMSLSLAPDTRLFVSGACDASAKLWDV 213
>BC068003-1|AAH68003.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + PD T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PDG F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 70.9 bits (166), Expect = 9e-12
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + +G + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>BC012348-1|AAH12348.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + PD T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PDG F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 70.9 bits (166), Expect = 9e-12
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + +G + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>BC010073-1|AAH10073.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + PD T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PDG F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 70.9 bits (166), Expect = 9e-12
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + +G + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>BC000873-1|AAH00873.1| 340|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 4 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 62/241 (25%), Positives = 107/241 (44%), Gaps = 10/241 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D L++ D +++ T + + + V Y P + V D+ ++N
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 286 VPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+ T + + R G LS D ++++S D A DI T Q T + SG
Sbjct: 126 LKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSG 185
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATA 402
+ + PD F +G ++ K+WD+++ +F GHV + ++SF NGY AT
Sbjct: 186 -DVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATG 244
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + + +N I + F +SG L +AG D + C W L
Sbjct: 245 SDDATCRLFDLRADQEL-LLYSHDNIICGITSVAFSKSGR-LLLAGYD--DFNCNVWDTL 300
Query: 461 K 461
K
Sbjct: 301 K 301
Score = 74.1 bits (174), Expect = 1e-12
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D S+++T D +++ +T Q GH+ V + PD T ++ + D + ++W+
Sbjct: 153 DDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQ-LLTKVSDFSGV 343
+ H + +S P G Y +T SD D+R Q LL D
Sbjct: 213 IRDGMCRQSFTGHVSDINAVSFFPNG-YAFATGSDDATCRLFDLRADQELLLYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +++W+
Sbjct: 332 WDSFLRIWN 340
Score = 64.9 bits (151), Expect = 6e-10
Identities = 57/237 (24%), Positives = 105/237 (44%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S S + + A D+ KLWD+R ++ +
Sbjct: 170 DIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVS-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G A D R++ R QEL +++ T V F K+ + L
Sbjct: 229 INAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLL 285
>AF501883-1|AAM15919.1| 340|Homo sapiens guanine nucleotide binding
protein beta 2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + PD T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PDG F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 70.9 bits (166), Expect = 9e-12
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + +G + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>AF300648-1|AAG18442.1| 340|Homo sapiens guanine nucleotide binding
protein beta subunit 4 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 62/241 (25%), Positives = 107/241 (44%), Gaps = 10/241 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D L++ D +++ T + + + V Y P + V D+ ++N
Sbjct: 66 DSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYN 125
Query: 286 VPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFSG 342
+ T + + R G LS D ++++S D A DI T Q T + SG
Sbjct: 126 LKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSG 185
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATA 402
+ + PD F +G ++ K+WD+++ +F GHV + ++SF NGY AT
Sbjct: 186 -DVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFATG 244
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQEL 460
++D+ +L+DLR + + +N I + F +SG L +AG D + C W L
Sbjct: 245 SDDATCRLFDLRADQEL-LLYSHDNIICGITSVAFSKSGR-LLLAGYD--DFNCNVWDTL 300
Query: 461 K 461
K
Sbjct: 301 K 301
Score = 74.1 bits (174), Expect = 1e-12
Identities = 43/189 (22%), Positives = 82/189 (43%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D S+++T D +++ +T Q GH+ V + PD T ++ + D + ++W+
Sbjct: 153 DDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQ-LLTKVSDFSGV 343
+ H + +S P G Y +T SD D+R Q LL D
Sbjct: 213 IRDGMCRQSFTGHVSDINAVSFFPNG-YAFATGSDDATCRLFDLRADQELLLYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ +WD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +++W+
Sbjct: 332 WDSFLRIWN 340
Score = 64.9 bits (151), Expect = 6e-10
Identities = 57/237 (24%), Positives = 105/237 (44%), Gaps = 9/237 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
YV D + +++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 YVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S S + + A D+ KLWD+R ++ +
Sbjct: 170 DIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVS-D 228
Query: 430 IKELCFDQSGTYLAIAGTDV--RVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G A D R++ R QEL +++ T V F K+ + L
Sbjct: 229 INAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLL 285
>AF053356-4|AAC78794.1| 340|Homo sapiens GNB2 protein.
Length = 340
Score = 77.8 bits (183), Expect = 8e-14
Identities = 45/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + PD T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 66/280 (23%), Positives = 121/280 (43%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y P + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + PDG F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 70.9 bits (166), Expect = 9e-12
Identities = 58/238 (24%), Positives = 109/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + +G + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>M16538-1|AAA35922.1| 340|Homo sapiens protein ( Human
signal-transducing guanine nucleotide-binding regulatory
(G) protein beta subunit mRNA, complete cds. ).
Length = 340
Score = 75.8 bits (178), Expect = 3e-13
Identities = 44/189 (23%), Positives = 86/189 (45%), Gaps = 3/189 (1%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++++T D +++ +T Q GH+ V + P+ T ++ + D +I++W+
Sbjct: 153 DDNQIITSSGDTTCALWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWA-FSDIRTGQLLTKVSDFSGV- 343
V S H+ + ++ P G Y +T SD D+R Q L S + +
Sbjct: 213 VRDSMCRQTFIGHESDINAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIIC 271
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+T+ F G + G ++ IWD + GH V+ + +++G +AT +
Sbjct: 272 GITSVAFSRSGRLLLAGYDDFNCNIWDAMKGDRAGVLAGHDNRVSCLGVTDDGMAVATGS 331
Query: 404 EDSCVKLWD 412
DS +K+W+
Sbjct: 332 WDSFLKIWN 340
Score = 70.1 bits (164), Expect = 2e-11
Identities = 64/280 (22%), Positives = 120/280 (42%), Gaps = 15/280 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D L++ D +++ T V + + V Y + V D+ ++
Sbjct: 65 TDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSGNFVACGGLDNICSIY 124
Query: 285 NVPTSQ-TTAILRSHDGPVTGLSLHPTGD--YVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
++ T + + R G LS D ++++S D A DI TGQ + S
Sbjct: 125 SLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCALWDIETGQQTVGFAGHS 184
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G + + P+G F +G ++ +K+WD+++ F GH + +++F NGY T
Sbjct: 185 G-DVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFTT 243
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTDVRVYLCRQWQE 459
++D+ +L+DLR + + +N I + F +SG L +AG D + C W
Sbjct: 244 GSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFSRSGR-LLLAGYD--DFNCNIWDA 299
Query: 460 LK-----VFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+K V H + + + +A+ S D LK++
Sbjct: 300 MKGDRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIW 339
Score = 69.3 bits (162), Expect = 3e-11
Identities = 58/238 (24%), Positives = 108/238 (45%), Gaps = 11/238 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + +W+ T+ + V + +G+
Sbjct: 51 LRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++T + +VS + G + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQII-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G V S+S + NG + A D+ +KLWD+R +T E+
Sbjct: 170 DIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTD---VRVYLCRQWQELKVFNDHT--ASATGVRFGKNAQYL 482
I + F +G Y G+D R++ R QEL +++ T V F ++ + L
Sbjct: 229 INAVAFFPNG-YAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLL 285
>BC026353-1|AAH26353.1| 677|Homo sapiens WD repeat domain 48
protein.
Length = 677
Score = 75.4 bits (177), Expect = 4e-13
Identities = 57/248 (22%), Positives = 113/248 (45%), Gaps = 13/248 (5%)
Query: 216 GILSLDINPSDHSKLLTGGND---RNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV 272
G+ +L ++P+ ++L T G D R +V + +A ++ HT V ++ + T+
Sbjct: 32 GVNALQLDPA-LNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTL 90
Query: 273 ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ 332
I+AS D T++VWN + LR+H V L+ + V S D+ D+ T
Sbjct: 91 ISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLT 150
Query: 333 LLT------KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
LT S SG S+ + + G I +G+ +++WD + + + GH
Sbjct: 151 ALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHT 210
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V ++ + +G + + D ++LW L + + T ++ + + L + + T++
Sbjct: 211 DNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE-GVWALQVNDAFTHVYS 269
Query: 445 AGTDVRVY 452
G D ++Y
Sbjct: 270 GGRDRKIY 277
Score = 55.6 bits (128), Expect = 4e-07
Identities = 45/218 (20%), Positives = 99/218 (45%), Gaps = 11/218 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT- 288
L++ +D V+N ++ L+ H V + Y D++ V +A D I +W+V T
Sbjct: 90 LISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 149
Query: 289 --------SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
+ TT+ L + + L+++ G ++S S+++ D RT L K+
Sbjct: 150 TALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGH 209
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+ ++ + DG +G+ + +++W L +Q +A + H V ++ ++ ++
Sbjct: 210 TD-NVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVY 268
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQS 438
+ D + DLR + + + EE + ++ D+S
Sbjct: 269 SGGRDRKIYCTDLRN-PDIRVLICEEKAPVLKMELDRS 305
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 1/119 (0%)
Query: 211 SASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDED 270
S + I SL +N + +++G ++ V++ T + LKGHT V ++ + D
Sbjct: 165 SGNKDSIYSLAMNQLG-TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGT 223
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
++ S D TIR+W++ + A R HD V L ++ +V S D+ +D+R
Sbjct: 224 QCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
Score = 40.7 bits (91), Expect = 0.012
Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 10/148 (6%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKL-- 416
+ + ++ VK+W+ + ++ H V +++++++ +A+A D + LWD+ L
Sbjct: 92 SASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTA 151
Query: 417 -----KNFKTIQLEENY-AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTA 468
T L N +I L +Q GT + T+ +RV+ R +L HT
Sbjct: 152 LTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTD 211
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + ++ S S D T++L+ +
Sbjct: 212 NVKALLLNRDGTQCLSGSSDGTIRLWSL 239
>AF468833-1|AAL78650.1| 677|Homo sapiens WD repeat endosomal
protein protein.
Length = 677
Score = 75.4 bits (177), Expect = 4e-13
Identities = 57/248 (22%), Positives = 113/248 (45%), Gaps = 13/248 (5%)
Query: 216 GILSLDINPSDHSKLLTGGND---RNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV 272
G+ +L ++P+ ++L T G D R +V + +A ++ HT V ++ + T+
Sbjct: 32 GVNALQLDPA-LNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTL 90
Query: 273 ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ 332
I+AS D T++VWN + LR+H V L+ + V S D+ D+ T
Sbjct: 91 ISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLT 150
Query: 333 LLT------KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
LT S SG S+ + + G I +G+ +++WD + + + GH
Sbjct: 151 ALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHT 210
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V ++ + +G + + D ++LW L + + T ++ + + L + + T++
Sbjct: 211 DNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE-GVWALQVNDAFTHVYS 269
Query: 445 AGTDVRVY 452
G D ++Y
Sbjct: 270 GGRDRKIY 277
Score = 55.6 bits (128), Expect = 4e-07
Identities = 45/218 (20%), Positives = 99/218 (45%), Gaps = 11/218 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT- 288
L++ +D V+N ++ L+ H V + Y D++ V +A D I +W+V T
Sbjct: 90 LISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 149
Query: 289 --------SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
+ TT+ L + + L+++ G ++S S+++ D RT L K+
Sbjct: 150 TALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGH 209
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+ ++ + DG +G+ + +++W L +Q +A + H V ++ ++ ++
Sbjct: 210 TD-NVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVY 268
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQS 438
+ D + DLR + + + EE + ++ D+S
Sbjct: 269 SGGRDRKIYCTDLRN-PDIRVLICEEKAPVLKMELDRS 305
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 1/119 (0%)
Query: 211 SASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDED 270
S + I SL +N + +++G ++ V++ T + LKGHT V ++ + D
Sbjct: 165 SGNKDSIYSLAMNQLG-TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGT 223
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
++ S D TIR+W++ + A R HD V L ++ +V S D+ +D+R
Sbjct: 224 QCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 282
Score = 40.7 bits (91), Expect = 0.012
Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 10/148 (6%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKL-- 416
+ + ++ VK+W+ + ++ H V +++++++ +A+A D + LWD+ L
Sbjct: 92 SASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTA 151
Query: 417 -----KNFKTIQLEENY-AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTA 468
T L N +I L +Q GT + T+ +RV+ R +L HT
Sbjct: 152 LTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTD 211
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + ++ S S D T++L+ +
Sbjct: 212 NVKALLLNRDGTQCLSGSSDGTIRLWSL 239
>AB209438-1|BAD92675.1| 316|Homo sapiens PWP2 periodic tryptophan
protein homolog protein.
Length = 316
Score = 75.4 bits (177), Expect = 4e-13
Identities = 41/154 (26%), Positives = 73/154 (47%), Gaps = 3/154 (1%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ + PDG TG ++ +VK+W+ F H VT ++F+ GY + T++
Sbjct: 95 SMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 154
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD---VRVYLCRQWQEL 460
D V+ +DL + +NF+T + D SG ++ D + V+ + + L
Sbjct: 155 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 214
Query: 461 KVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
V + H +G+ F LAS S D+T++L+
Sbjct: 215 DVLSGHEGPISGLCFNPMKSVLASASWDKTVRLW 248
Score = 72.9 bits (171), Expect = 2e-12
Identities = 41/174 (23%), Positives = 76/174 (43%), Gaps = 1/174 (0%)
Query: 241 VFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDG 300
V+ +E V +GH + + Y PD ++T D ++VWN + H
Sbjct: 77 VWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSS 136
Query: 301 PVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTG 360
VTG++ TG V+++S D D+ + + + G I G
Sbjct: 137 GVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAG 196
Query: 361 TENS-QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
++S ++ +W ++ + GH GP++ + F+ LA+A+ D V+LWD+
Sbjct: 197 AQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDM 250
Score = 44.4 bits (100), Expect = 0.001
Identities = 23/101 (22%), Positives = 49/101 (48%), Gaps = 3/101 (2%)
Query: 365 QVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
Q+ +W+ + +S V GH + ++++S +G Y+ T +D VK+W+ F T
Sbjct: 74 QLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTF-T 132
Query: 425 EENYAIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVF 463
E + + + F +G + + D VR + +++ + F
Sbjct: 133 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTF 173
Score = 44.4 bits (100), Expect = 0.001
Identities = 35/157 (22%), Positives = 75/157 (47%), Gaps = 4/157 (2%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+++L +P D ++TGG+D V+N + H+ VT V + V+T+S
Sbjct: 96 MVALAYSP-DGQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSS 154
Query: 277 PDHTIRVWNVPTSQTTAILRS-HDGPVTGLSLHPTGDYVLSTSSDQHWAFS-DIRTGQLL 334
D T+R +++ + S + +++ +G+ V + + D F ++TG+LL
Sbjct: 155 MDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEIVSAGAQDSFEIFVWSMQTGRLL 214
Query: 335 TKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
+S G ++ F+P + + + + V++WD+
Sbjct: 215 DVLSGHEG-PISGLCFNPMKSVLASASWDKTVRLWDM 250
Score = 34.3 bits (75), Expect = 1.0
Identities = 14/52 (26%), Positives = 32/52 (61%)
Query: 241 VFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTT 292
V++ T +++ +L GH ++ + ++P + + +AS D T+R+W++ S T
Sbjct: 205 VWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWDMFDSWRT 256
Score = 33.5 bits (73), Expect = 1.8
Identities = 18/69 (26%), Positives = 32/69 (46%), Gaps = 8/69 (11%)
Query: 433 LCFDQSGTYLAIAGTDVRVYLCRQWQELK-----VFNDHTASATGVRFGKNAQYLASTSM 487
L + G Y+ G D +V + W L F +H++ TGV F + ++SM
Sbjct: 99 LAYSPDGQYIVTGGDDGKV---KVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSM 155
Query: 488 DRTLKLYGI 496
D T++ + +
Sbjct: 156 DGTVRAFDL 164
>AB040882-1|BAA95973.2| 680|Homo sapiens KIAA1449 protein protein.
Length = 680
Score = 75.4 bits (177), Expect = 4e-13
Identities = 57/248 (22%), Positives = 113/248 (45%), Gaps = 13/248 (5%)
Query: 216 GILSLDINPSDHSKLLTGGND---RNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV 272
G+ +L ++P+ ++L T G D R +V + +A ++ HT V ++ + T+
Sbjct: 35 GVNALQLDPA-LNRLFTAGRDSIIRIWSVNQHKQDPYIASMEHHTDWVNDIVLCCNGKTL 93
Query: 273 ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQ 332
I+AS D T++VWN + LR+H V L+ + V S D+ D+ T
Sbjct: 94 ISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLT 153
Query: 333 LLT------KVSDFSG--VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHV 384
LT S SG S+ + + G I +G+ +++WD + + + GH
Sbjct: 154 ALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHT 213
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
V ++ + +G + + D ++LW L + + T ++ + + L + + T++
Sbjct: 214 DNVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDE-GVWALQVNDAFTHVYS 272
Query: 445 AGTDVRVY 452
G D ++Y
Sbjct: 273 GGRDRKIY 280
Score = 55.6 bits (128), Expect = 4e-07
Identities = 45/218 (20%), Positives = 99/218 (45%), Gaps = 11/218 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT- 288
L++ +D V+N ++ L+ H V + Y D++ V +A D I +W+V T
Sbjct: 93 LISASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTL 152
Query: 289 --------SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDF 340
+ TT+ L + + L+++ G ++S S+++ D RT L K+
Sbjct: 153 TALTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGH 212
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLA 400
+ ++ + DG +G+ + +++W L +Q +A + H V ++ ++ ++
Sbjct: 213 TD-NVKALLLNRDGTQCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVY 271
Query: 401 TAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQS 438
+ D + DLR + + + EE + ++ D+S
Sbjct: 272 SGGRDRKIYCTDLRN-PDIRVLICEEKAPVLKMELDRS 308
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/119 (26%), Positives = 58/119 (48%), Gaps = 1/119 (0%)
Query: 211 SASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDED 270
S + I SL +N + +++G ++ V++ T + LKGHT V ++ + D
Sbjct: 168 SGNKDSIYSLAMNQLG-TIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGT 226
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
++ S D TIR+W++ + A R HD V L ++ +V S D+ +D+R
Sbjct: 227 QCLSGSSDGTIRLWSLGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDLR 285
Score = 40.7 bits (91), Expect = 0.012
Identities = 32/148 (21%), Positives = 67/148 (45%), Gaps = 10/148 (6%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKL-- 416
+ + ++ VK+W+ + ++ H V +++++++ +A+A D + LWD+ L
Sbjct: 95 SASSDTTVKVWNAHKGFCMSTLRTHKDYVKALAYAKDKELVASAGLDRQIFLWDVNTLTA 154
Query: 417 -----KNFKTIQLEENY-AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQELKVFNDHTA 468
T L N +I L +Q GT + T+ +RV+ R +L HT
Sbjct: 155 LTASNNTVTTSSLSGNKDSIYSLAMNQLGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTD 214
Query: 469 SATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ + ++ S S D T++L+ +
Sbjct: 215 NVKALLLNRDGTQCLSGSSDGTIRLWSL 242
>U05340-1|AAA19017.1| 499|Homo sapiens p55CDC protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>DQ473545-1|ABE96834.1| 499|Homo sapiens CDC20 cell division cycle
20 homolog protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BT007388-1|AAP36052.1| 499|Homo sapiens CDC20 cell division cycle
20 homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC110321-1|AAI10322.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC031294-1|AAH31294.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC024257-1|AAH24257.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC015998-1|AAH15998.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC013303-1|AAH13303.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC012827-1|AAH12827.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC012803-1|AAH12803.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC010044-1|AAH10044.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC009426-1|AAH09426.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC009425-1|AAH09425.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC006272-1|AAH06272.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC001088-1|AAH01088.1| 499|Homo sapiens cell division cycle 20
homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>BC000624-1|AAH00624.1| 499|Homo sapiens CDC20 protein protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>AL139289-3|CAB92757.1| 499|Homo sapiens CDC20 cell division cycle
20 homolog (S. cerevisiae) protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>AF099644-1|AAD16405.1| 499|Homo sapiens cell cycle protein CDC20
protein.
Length = 499
Score = 74.9 bits (176), Expect = 6e-13
Identities = 61/221 (27%), Positives = 103/221 (46%), Gaps = 11/221 (4%)
Query: 227 HSKLLTGGNDRNATVFNKDT---EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV 283
+S +L+ G+ R+ + + D E VA L GH+++V + + PD + + D+ + V
Sbjct: 277 NSYILSSGS-RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNV 335
Query: 284 W-NVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLST---SSDQHWAFSDIRTGQLLTK 336
W + P L++ H G V ++ P VL+T +SD+H ++ +G L+
Sbjct: 336 WPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSA 395
Query: 337 VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG 396
V S V H LI G G +Q+ IW + VA GH V S++ S +G
Sbjct: 396 VDAHSQVCSILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSPDG 455
Query: 397 YYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ 437
+A+AA D ++LW +L + + E+ A K Q
Sbjct: 456 ATVASAAADETLRLWRCFELDPARRREREKASAAKSSLIHQ 496
Score = 46.4 bits (105), Expect = 2e-04
Identities = 39/193 (20%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 314 VLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
VL+ + D +G +L + + G +++ + +G GT +++V++WD++
Sbjct: 197 VLAVALDNSVYLWSASSGDILQLLQMEQPGEYISSVAWIKEGNYLAVGTSSAEVQLWDVQ 256
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+Q + N H V S+S+ N Y L++ + + D+R ++ + +
Sbjct: 257 QQKRLRNMTSHSARVGSLSW--NSYILSSGSRSGHIHHHDVRVAEHHVATLSGHSQEVCG 314
Query: 433 LCFDQSGTYLAIAGTD--VRVYLCRQ----WQELKVFNDHTASATGVR---FGKNAQYLA 483
L + G +LA G D V V+ W L+ F H + V + N
Sbjct: 315 LRWAPDGRHLASGGNDNLVNVWPSAPGEGGWVPLQTFTQHQGAVKAVAWCPWQSNVLATG 374
Query: 484 STSMDRTLKLYGI 496
+ DR ++++ +
Sbjct: 375 GGTSDRHIRIWNV 387
>M95627-1|AAA68889.1| 452|Homo sapiens angio-associated migratory
cell protein protein.
Length = 452
Score = 74.5 bits (175), Expect = 8e-13
Identities = 53/205 (25%), Positives = 90/205 (43%), Gaps = 10/205 (4%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
LHSASV + ++P ++ +TGG D A V+ +++ GH VT + D
Sbjct: 107 LHSASV---FCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHD 163
Query: 269 EDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDI 328
V T ++VW V T + + G + + HP +L+ ++D + +
Sbjct: 164 STLVATGDMSGLLKVWQVDTKE--EVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKV 221
Query: 329 RTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNV---ANFPGHVG 385
G K T + PDG G E+ ++IWDLK+ S + GH G
Sbjct: 222 PNGD--CKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQG 279
Query: 386 PVTSISFSENGYYLATAAEDSCVKL 410
P+T ++ +++G + T + D KL
Sbjct: 280 PLTCVAANQDGSLILTGSVDCQAKL 304
Score = 38.3 bits (85), Expect = 0.062
Identities = 42/203 (20%), Positives = 73/203 (35%), Gaps = 11/203 (5%)
Query: 256 HTKKVTRVIYHPDEDTV-ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
H+ V V P +T+ +T D VW + + H VT + D
Sbjct: 108 HSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGF--SHDST 165
Query: 315 LSTSSDQHWAFSDIRTGQLLTK--VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
L + D ++ Q+ TK V F L ++HP + GT + +W +
Sbjct: 166 LVATGDMSGL---LKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVP 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ F G P T +G ED +++WDL++ ++ E +
Sbjct: 223 N-GDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPL 281
Query: 433 LCF--DQSGTYLAIAGTDVRVYL 453
C +Q G+ + D + L
Sbjct: 282 TCVAANQDGSLILTGSVDCQAKL 304
Score = 35.1 bits (77), Expect = 0.57
Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLSTSSDQHW 323
PD + D TIR+W++ +L+ H GP+T ++ + G +L+ S D
Sbjct: 243 PDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQA 302
Query: 324 AFSDIRTGQLL 334
TG+++
Sbjct: 303 KLVSATTGKVV 313
Score = 33.9 bits (74), Expect = 1.3
Identities = 15/65 (23%), Positives = 28/65 (43%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H + ++++ V T S D +R+W+ T + R H + +L V+
Sbjct: 375 HQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVV 434
Query: 316 STSSD 320
+TS D
Sbjct: 435 TTSGD 439
>CR456755-1|CAG33036.1| 452|Homo sapiens AAMP protein.
Length = 452
Score = 74.5 bits (175), Expect = 8e-13
Identities = 53/205 (25%), Positives = 90/205 (43%), Gaps = 10/205 (4%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
LHSASV + ++P ++ +TGG D A V+ +++ GH VT + D
Sbjct: 107 LHSASV---FCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHD 163
Query: 269 EDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDI 328
V T ++VW V T + + G + + HP +L+ ++D + +
Sbjct: 164 STLVATGDMSGLLKVWQVDTKE--EVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKV 221
Query: 329 RTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNV---ANFPGHVG 385
G K T + PDG G E+ ++IWDLK+ S + GH G
Sbjct: 222 PNGD--CKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQG 279
Query: 386 PVTSISFSENGYYLATAAEDSCVKL 410
P+T ++ +++G + T + D KL
Sbjct: 280 PLTCVAANQDGSLILTGSVDCQAKL 304
Score = 38.3 bits (85), Expect = 0.062
Identities = 42/203 (20%), Positives = 73/203 (35%), Gaps = 11/203 (5%)
Query: 256 HTKKVTRVIYHPDEDTV-ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
H+ V V P +T+ +T D VW + + H VT + D
Sbjct: 108 HSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGF--SHDST 165
Query: 315 LSTSSDQHWAFSDIRTGQLLTK--VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
L + D ++ Q+ TK V F L ++HP + GT + +W +
Sbjct: 166 LVATGDMSGL---LKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVP 222
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ F G P T +G ED +++WDL++ ++ E +
Sbjct: 223 N-GDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPL 281
Query: 433 LCF--DQSGTYLAIAGTDVRVYL 453
C +Q G+ + D + L
Sbjct: 282 TCVAANQDGSLILTGSVDCQAKL 304
Score = 35.1 bits (77), Expect = 0.57
Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLSTSSDQHW 323
PD + D TIR+W++ +L+ H GP+T ++ + G +L+ S D
Sbjct: 243 PDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQA 302
Query: 324 AFSDIRTGQLL 334
TG+++
Sbjct: 303 KLVSATTGKVV 313
Score = 33.9 bits (74), Expect = 1.3
Identities = 15/65 (23%), Positives = 28/65 (43%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H + ++++ V T S D +R+W+ T + R H + +L V+
Sbjct: 375 HQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVV 434
Query: 316 STSSD 320
+TS D
Sbjct: 435 TTSGD 439
>BC039866-1|AAH39866.2| 434|Homo sapiens angio-associated,
migratory cell protein protein.
Length = 434
Score = 74.5 bits (175), Expect = 8e-13
Identities = 53/205 (25%), Positives = 90/205 (43%), Gaps = 10/205 (4%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
LHSASV + ++P ++ +TGG D A V+ +++ GH VT + D
Sbjct: 89 LHSASV---FCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHD 145
Query: 269 EDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDI 328
V T ++VW V T + + G + + HP +L+ ++D + +
Sbjct: 146 STLVATGDMSGLLKVWQVDTKE--EVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKV 203
Query: 329 RTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNV---ANFPGHVG 385
G K T + PDG G E+ ++IWDLK+ S + GH G
Sbjct: 204 PNGD--CKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQG 261
Query: 386 PVTSISFSENGYYLATAAEDSCVKL 410
P+T ++ +++G + T + D KL
Sbjct: 262 PLTCVAANQDGSLILTGSVDCQAKL 286
Score = 38.3 bits (85), Expect = 0.062
Identities = 42/203 (20%), Positives = 73/203 (35%), Gaps = 11/203 (5%)
Query: 256 HTKKVTRVIYHPDEDTV-ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
H+ V V P +T+ +T D VW + + H VT + D
Sbjct: 90 HSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGF--SHDST 147
Query: 315 LSTSSDQHWAFSDIRTGQLLTK--VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
L + D ++ Q+ TK V F L ++HP + GT + +W +
Sbjct: 148 LVATGDMSGL---LKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVP 204
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ F G P T +G ED +++WDL++ ++ E +
Sbjct: 205 N-GDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPL 263
Query: 433 LCF--DQSGTYLAIAGTDVRVYL 453
C +Q G+ + D + L
Sbjct: 264 TCVAANQDGSLILTGSVDCQAKL 286
Score = 35.1 bits (77), Expect = 0.57
Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLSTSSDQHW 323
PD + D TIR+W++ +L+ H GP+T ++ + G +L+ S D
Sbjct: 225 PDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQA 284
Query: 324 AFSDIRTGQLL 334
TG+++
Sbjct: 285 KLVSATTGKVV 295
Score = 33.9 bits (74), Expect = 1.3
Identities = 15/65 (23%), Positives = 28/65 (43%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H + ++++ V T S D +R+W+ T + R H + +L V+
Sbjct: 357 HQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVV 416
Query: 316 STSSD 320
+TS D
Sbjct: 417 TTSGD 421
>BC020244-1|AAH20244.1| 429|Homo sapiens Similar to
angio-associated, migratory cell protein protein.
Length = 429
Score = 74.5 bits (175), Expect = 8e-13
Identities = 53/205 (25%), Positives = 90/205 (43%), Gaps = 10/205 (4%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
LHSASV + ++P ++ +TGG D A V+ +++ GH VT + D
Sbjct: 84 LHSASV---FCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHD 140
Query: 269 EDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDI 328
V T ++VW V T + + G + + HP +L+ ++D + +
Sbjct: 141 STLVATGDMSGLLKVWQVDTKE--EVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKV 198
Query: 329 RTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNV---ANFPGHVG 385
G K T + PDG G E+ ++IWDLK+ S + GH G
Sbjct: 199 PNGD--CKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQG 256
Query: 386 PVTSISFSENGYYLATAAEDSCVKL 410
P+T ++ +++G + T + D KL
Sbjct: 257 PLTCVAANQDGSLILTGSVDCQAKL 281
Score = 38.3 bits (85), Expect = 0.062
Identities = 42/203 (20%), Positives = 73/203 (35%), Gaps = 11/203 (5%)
Query: 256 HTKKVTRVIYHPDEDTV-ITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
H+ V V P +T+ +T D VW + + H VT + D
Sbjct: 85 HSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGF--SHDST 142
Query: 315 LSTSSDQHWAFSDIRTGQLLTK--VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLK 372
L + D ++ Q+ TK V F L ++HP + GT + +W +
Sbjct: 143 LVATGDMSGL---LKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVP 199
Query: 373 EQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKE 432
+ F G P T +G ED +++WDL++ ++ E +
Sbjct: 200 N-GDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPL 258
Query: 433 LCF--DQSGTYLAIAGTDVRVYL 453
C +Q G+ + D + L
Sbjct: 259 TCVAANQDGSLILTGSVDCQAKL 281
Score = 35.1 bits (77), Expect = 0.57
Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 3/71 (4%)
Query: 267 PDEDTVITASPDHTIRVWNVPTSQTTAILRS---HDGPVTGLSLHPTGDYVLSTSSDQHW 323
PD + D TIR+W++ +L+ H GP+T ++ + G +L+ S D
Sbjct: 220 PDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVAANQDGSLILTGSVDCQA 279
Query: 324 AFSDIRTGQLL 334
TG+++
Sbjct: 280 KLVSATTGKVV 290
Score = 33.9 bits (74), Expect = 1.3
Identities = 15/65 (23%), Positives = 28/65 (43%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H + ++++ V T S D +R+W+ T + R H + +L V+
Sbjct: 352 HQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVV 411
Query: 316 STSSD 320
+TS D
Sbjct: 412 TTSGD 416
>AL163279-2|CAB90452.1| 2295|Homo sapiens homolog to cAMP response
element binding and betadogene protein.
Length = 2295
Score = 74.5 bits (175), Expect = 8e-13
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D +++ ++++ L+GH+ +++ + + + + S D IRVW + T
Sbjct: 226 RIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRT 285
Query: 289 SQTTAILRSHDGPVTGLSLHPTGD----YVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H G +T L P Y++ST +D W ++ K ++
Sbjct: 286 CAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTE 345
Query: 340 --FSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL--KEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ L + +A H V SI F N
Sbjct: 346 KPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNN 405
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
G + + D ++W +L+ +++I L+
Sbjct: 406 GDRFLSGSRDGTARIWRFEQLE-WRSILLD 434
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G+ + T ++D VK+W + T++ + I ++ + T
Sbjct: 210 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLR-GHSAEISDMAVNYENTM 268
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNA----QYLASTSMDRTL 491
+A D +RV+ R + V HT S T ++F A +Y+ ST D T+
Sbjct: 269 IAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTV 324
Score = 42.3 bits (95), Expect = 0.004
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 274 TASPDHTIRVW--NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSDI 328
T S DH IR++ + A L SH V + GD LS S D + W F +
Sbjct: 367 TGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQL 426
Query: 329 R------------TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN 376
+G L ++ F +T ++ + I T + +K+W+
Sbjct: 427 EWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQL 486
Query: 377 VANFPGHVGPVTSI-SFSENGYYLATAAEDSCVKLWDL---RKLKN-FKTIQLEENYAIK 431
+ N GH V + + + + +A D + +WD+ K+K+ F I+ + + A+
Sbjct: 487 LHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVF 546
Query: 432 ELCFDQSGTYLA 443
+ F Q G + A
Sbjct: 547 DCKFSQDGQHFA 558
Score = 42.3 bits (95), Expect = 0.004
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV-LST 317
KVT + ++ ++ V+TA DH ++VWN T Q L H V L HP + LS
Sbjct: 454 KVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSA 513
Query: 318 SSDQHWAFSDIRTG 331
D DI G
Sbjct: 514 GHDGSIFIWDITKG 527
Score = 41.9 bits (94), Expect = 0.005
Identities = 40/185 (21%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W+ + + LR H ++ ++++ +
Sbjct: 210 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMI 269
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + +G S+T+ QF P + TG + + Q
Sbjct: 270 AAGSCDKIIRVWCLRTCAPVAVLQGHTG-SITSLQFSPMAKGSQRYMVSTGADGTVCFWQ 328
Query: 366 VKIWDLKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ LK F P + SFS G +LAT + D ++++ L K
Sbjct: 329 WDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIA 388
Query: 423 QLEEN 427
+LE +
Sbjct: 389 ELESH 393
Score = 35.5 bits (78), Expect = 0.43
Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Query: 215 PGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVI 273
P + + N +D S ++T ND V+N T Q++ L GH +V + HP D ++
Sbjct: 453 PKVTMIAWNQND-SIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIML 511
Query: 274 TASPDHTIRVWNV 286
+A D +I +W++
Sbjct: 512 SAGHDGSIFIWDI 524
>AJ292466-1|CAC44372.1| 2269|Homo sapiens WDR9 protein, form B
protein.
Length = 2269
Score = 74.5 bits (175), Expect = 8e-13
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D +++ ++++ L+GH+ +++ + + + + S D IRVW + T
Sbjct: 200 RIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRT 259
Query: 289 SQTTAILRSHDGPVTGLSLHPTGD----YVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H G +T L P Y++ST +D W ++ K ++
Sbjct: 260 CAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTE 319
Query: 340 --FSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL--KEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ L + +A H V SI F N
Sbjct: 320 KPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNN 379
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
G + + D ++W +L+ +++I L+
Sbjct: 380 GDRFLSGSRDGTARIWRFEQLE-WRSILLD 408
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G+ + T ++D VK+W + T++ + I ++ + T
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLR-GHSAEISDMAVNYENTM 242
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNA----QYLASTSMDRTL 491
+A D +RV+ R + V HT S T ++F A +Y+ ST D T+
Sbjct: 243 IAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTV 298
Score = 42.3 bits (95), Expect = 0.004
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 274 TASPDHTIRVW--NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSDI 328
T S DH IR++ + A L SH V + GD LS S D + W F +
Sbjct: 341 TGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQL 400
Query: 329 R------------TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN 376
+G L ++ F +T ++ + I T + +K+W+
Sbjct: 401 EWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQL 460
Query: 377 VANFPGHVGPVTSI-SFSENGYYLATAAEDSCVKLWDL---RKLKN-FKTIQLEENYAIK 431
+ N GH V + + + + +A D + +WD+ K+K+ F I+ + + A+
Sbjct: 461 LHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVF 520
Query: 432 ELCFDQSGTYLA 443
+ F Q G + A
Sbjct: 521 DCKFSQDGQHFA 532
Score = 42.3 bits (95), Expect = 0.004
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV-LST 317
KVT + ++ ++ V+TA DH ++VWN T Q L H V L HP + LS
Sbjct: 428 KVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSA 487
Query: 318 SSDQHWAFSDIRTG 331
D DI G
Sbjct: 488 GHDGSIFIWDITKG 501
Score = 41.9 bits (94), Expect = 0.005
Identities = 40/185 (21%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W+ + + LR H ++ ++++ +
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMI 243
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + +G S+T+ QF P + TG + + Q
Sbjct: 244 AAGSCDKIIRVWCLRTCAPVAVLQGHTG-SITSLQFSPMAKGSQRYMVSTGADGTVCFWQ 302
Query: 366 VKIWDLKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ LK F P + SFS G +LAT + D ++++ L K
Sbjct: 303 WDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIA 362
Query: 423 QLEEN 427
+LE +
Sbjct: 363 ELESH 367
Score = 35.5 bits (78), Expect = 0.43
Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Query: 215 PGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVI 273
P + + N +D S ++T ND V+N T Q++ L GH +V + HP D ++
Sbjct: 427 PKVTMIAWNQND-SIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIML 485
Query: 274 TASPDHTIRVWNV 286
+A D +I +W++
Sbjct: 486 SAGHDGSIFIWDI 498
>AJ292465-1|CAC44371.1| 2320|Homo sapiens WDR9 protein, form A
protein.
Length = 2320
Score = 74.5 bits (175), Expect = 8e-13
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D +++ ++++ L+GH+ +++ + + + + S D IRVW + T
Sbjct: 200 RIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRT 259
Query: 289 SQTTAILRSHDGPVTGLSLHPTGD----YVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H G +T L P Y++ST +D W ++ K ++
Sbjct: 260 CAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTE 319
Query: 340 --FSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL--KEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ L + +A H V SI F N
Sbjct: 320 KPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNN 379
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
G + + D ++W +L+ +++I L+
Sbjct: 380 GDRFLSGSRDGTARIWRFEQLE-WRSILLD 408
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G+ + T ++D VK+W + T++ + I ++ + T
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLR-GHSAEISDMAVNYENTM 242
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNA----QYLASTSMDRTL 491
+A D +RV+ R + V HT S T ++F A +Y+ ST D T+
Sbjct: 243 IAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTV 298
Score = 42.3 bits (95), Expect = 0.004
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 274 TASPDHTIRVW--NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSDI 328
T S DH IR++ + A L SH V + GD LS S D + W F +
Sbjct: 341 TGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQL 400
Query: 329 R------------TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN 376
+G L ++ F +T ++ + I T + +K+W+
Sbjct: 401 EWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQL 460
Query: 377 VANFPGHVGPVTSI-SFSENGYYLATAAEDSCVKLWDL---RKLKN-FKTIQLEENYAIK 431
+ N GH V + + + + +A D + +WD+ K+K+ F I+ + + A+
Sbjct: 461 LHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVF 520
Query: 432 ELCFDQSGTYLA 443
+ F Q G + A
Sbjct: 521 DCKFSQDGQHFA 532
Score = 42.3 bits (95), Expect = 0.004
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV-LST 317
KVT + ++ ++ V+TA DH ++VWN T Q L H V L HP + LS
Sbjct: 428 KVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSA 487
Query: 318 SSDQHWAFSDIRTG 331
D DI G
Sbjct: 488 GHDGSIFIWDITKG 501
Score = 41.9 bits (94), Expect = 0.005
Identities = 40/185 (21%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W+ + + LR H ++ ++++ +
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMI 243
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + +G S+T+ QF P + TG + + Q
Sbjct: 244 AAGSCDKIIRVWCLRTCAPVAVLQGHTG-SITSLQFSPMAKGSQRYMVSTGADGTVCFWQ 302
Query: 366 VKIWDLKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ LK F P + SFS G +LAT + D ++++ L K
Sbjct: 303 WDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIA 362
Query: 423 QLEEN 427
+LE +
Sbjct: 363 ELESH 367
Score = 35.5 bits (78), Expect = 0.43
Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Query: 215 PGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVI 273
P + + N +D S ++T ND V+N T Q++ L GH +V + HP D ++
Sbjct: 427 PKVTMIAWNQND-SIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIML 485
Query: 274 TASPDHTIRVWNV 286
+A D +I +W++
Sbjct: 486 SAGHDGSIFIWDI 498
>AJ238214-1|CAC37033.2| 2269|Homo sapiens hypothetical protein
protein.
Length = 2269
Score = 74.5 bits (175), Expect = 8e-13
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D +++ ++++ L+GH+ +++ + + + + S D IRVW + T
Sbjct: 200 RIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRT 259
Query: 289 SQTTAILRSHDGPVTGLSLHPTGD----YVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H G +T L P Y++ST +D W ++ K ++
Sbjct: 260 CAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTE 319
Query: 340 --FSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL--KEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ L + +A H V SI F N
Sbjct: 320 KPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNN 379
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
G + + D ++W +L+ +++I L+
Sbjct: 380 GDRFLSGSRDGTARIWRFEQLE-WRSILLD 408
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G+ + T ++D VK+W + T++ + I ++ + T
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLR-GHSAEISDMAVNYENTM 242
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNA----QYLASTSMDRTL 491
+A D +RV+ R + V HT S T ++F A +Y+ ST D T+
Sbjct: 243 IAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTV 298
Score = 42.3 bits (95), Expect = 0.004
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 274 TASPDHTIRVW--NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSDI 328
T S DH IR++ + A L SH V + GD LS S D + W F +
Sbjct: 341 TGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQL 400
Query: 329 R------------TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN 376
+G L ++ F +T ++ + I T + +K+W+
Sbjct: 401 EWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQL 460
Query: 377 VANFPGHVGPVTSI-SFSENGYYLATAAEDSCVKLWDL---RKLKN-FKTIQLEENYAIK 431
+ N GH V + + + + +A D + +WD+ K+K+ F I+ + + A+
Sbjct: 461 LHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVF 520
Query: 432 ELCFDQSGTYLA 443
+ F Q G + A
Sbjct: 521 DCKFSQDGQHFA 532
Score = 42.3 bits (95), Expect = 0.004
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV-LST 317
KVT + ++ ++ V+TA DH ++VWN T Q L H V L HP + LS
Sbjct: 428 KVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSA 487
Query: 318 SSDQHWAFSDIRTG 331
D DI G
Sbjct: 488 GHDGSIFIWDITKG 501
Score = 41.9 bits (94), Expect = 0.005
Identities = 40/185 (21%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W+ + + LR H ++ ++++ +
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMI 243
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + +G S+T+ QF P + TG + + Q
Sbjct: 244 AAGSCDKIIRVWCLRTCAPVAVLQGHTG-SITSLQFSPMAKGSQRYMVSTGADGTVCFWQ 302
Query: 366 VKIWDLKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ LK F P + SFS G +LAT + D ++++ L K
Sbjct: 303 WDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIA 362
Query: 423 QLEEN 427
+LE +
Sbjct: 363 ELESH 367
Score = 35.5 bits (78), Expect = 0.43
Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Query: 215 PGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVI 273
P + + N +D S ++T ND V+N T Q++ L GH +V + HP D ++
Sbjct: 427 PKVTMIAWNQND-SIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIML 485
Query: 274 TASPDHTIRVWNV 286
+A D +I +W++
Sbjct: 486 SAGHDGSIFIWDI 498
>AB080587-1|BAD74072.1| 2199|Homo sapiens WD repeat protein
WDR9-form2 protein.
Length = 2199
Score = 74.5 bits (175), Expect = 8e-13
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D +++ ++++ L+GH+ +++ + + + + S D IRVW + T
Sbjct: 200 RIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRT 259
Query: 289 SQTTAILRSHDGPVTGLSLHPTGD----YVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H G +T L P Y++ST +D W ++ K ++
Sbjct: 260 CAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTE 319
Query: 340 --FSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL--KEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ L + +A H V SI F N
Sbjct: 320 KPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNN 379
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
G + + D ++W +L+ +++I L+
Sbjct: 380 GDRFLSGSRDGTARIWRFEQLE-WRSILLD 408
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G+ + T ++D VK+W + T++ + I ++ + T
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLR-GHSAEISDMAVNYENTM 242
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNA----QYLASTSMDRTL 491
+A D +RV+ R + V HT S T ++F A +Y+ ST D T+
Sbjct: 243 IAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTV 298
Score = 42.3 bits (95), Expect = 0.004
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 274 TASPDHTIRVW--NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSDI 328
T S DH IR++ + A L SH V + GD LS S D + W F +
Sbjct: 341 TGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQL 400
Query: 329 R------------TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN 376
+G L ++ F +T ++ + I T + +K+W+
Sbjct: 401 EWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQL 460
Query: 377 VANFPGHVGPVTSI-SFSENGYYLATAAEDSCVKLWDL---RKLKN-FKTIQLEENYAIK 431
+ N GH V + + + + +A D + +WD+ K+K+ F I+ + + A+
Sbjct: 461 LHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVF 520
Query: 432 ELCFDQSGTYLA 443
+ F Q G + A
Sbjct: 521 DCKFSQDGQHFA 532
Score = 42.3 bits (95), Expect = 0.004
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV-LST 317
KVT + ++ ++ V+TA DH ++VWN T Q L H V L HP + LS
Sbjct: 428 KVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSA 487
Query: 318 SSDQHWAFSDIRTG 331
D DI G
Sbjct: 488 GHDGSIFIWDITKG 501
Score = 41.9 bits (94), Expect = 0.005
Identities = 40/185 (21%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W+ + + LR H ++ ++++ +
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMI 243
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + +G S+T+ QF P + TG + + Q
Sbjct: 244 AAGSCDKIIRVWCLRTCAPVAVLQGHTG-SITSLQFSPMAKGSQRYMVSTGADGTVCFWQ 302
Query: 366 VKIWDLKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ LK F P + SFS G +LAT + D ++++ L K
Sbjct: 303 WDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIA 362
Query: 423 QLEEN 427
+LE +
Sbjct: 363 ELESH 367
Score = 35.5 bits (78), Expect = 0.43
Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Query: 215 PGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVI 273
P + + N +D S ++T ND V+N T Q++ L GH +V + HP D ++
Sbjct: 427 PKVTMIAWNQND-SIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIML 485
Query: 274 TASPDHTIRVWNV 286
+A D +I +W++
Sbjct: 486 SAGHDGSIFIWDI 498
>AB080586-1|BAD74071.1| 2269|Homo sapiens WD repeat protein protein.
Length = 2269
Score = 74.5 bits (175), Expect = 8e-13
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D +++ ++++ L+GH+ +++ + + + + S D IRVW + T
Sbjct: 200 RIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRT 259
Query: 289 SQTTAILRSHDGPVTGLSLHPTGD----YVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H G +T L P Y++ST +D W ++ K ++
Sbjct: 260 CAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTE 319
Query: 340 --FSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL--KEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ L + +A H V SI F N
Sbjct: 320 KPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNN 379
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
G + + D ++W +L+ +++I L+
Sbjct: 380 GDRFLSGSRDGTARIWRFEQLE-WRSILLD 408
Score = 50.8 bits (116), Expect = 1e-05
Identities = 30/116 (25%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G+ + T ++D VK+W + T++ + I ++ + T
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLR-GHSAEISDMAVNYENTM 242
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNA----QYLASTSMDRTL 491
+A D +RV+ R + V HT S T ++F A +Y+ ST D T+
Sbjct: 243 IAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTV 298
Score = 42.3 bits (95), Expect = 0.004
Identities = 44/192 (22%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 274 TASPDHTIRVW--NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSDI 328
T S DH IR++ + A L SH V + GD LS S D + W F +
Sbjct: 341 TGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQL 400
Query: 329 R------------TGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN 376
+G L ++ F +T ++ + I T + +K+W+
Sbjct: 401 EWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQL 460
Query: 377 VANFPGHVGPVTSI-SFSENGYYLATAAEDSCVKLWDL---RKLKN-FKTIQLEENYAIK 431
+ N GH V + + + + +A D + +WD+ K+K+ F I+ + + A+
Sbjct: 461 LHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVF 520
Query: 432 ELCFDQSGTYLA 443
+ F Q G + A
Sbjct: 521 DCKFSQDGQHFA 532
Score = 42.3 bits (95), Expect = 0.004
Identities = 25/74 (33%), Positives = 34/74 (45%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV-LST 317
KVT + ++ ++ V+TA DH ++VWN T Q L H V L HP + LS
Sbjct: 428 KVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSA 487
Query: 318 SSDQHWAFSDIRTG 331
D DI G
Sbjct: 488 GHDGSIFIWDITKG 501
Score = 41.9 bits (94), Expect = 0.005
Identities = 40/185 (21%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W+ + + LR H ++ ++++ +
Sbjct: 184 GHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMI 243
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + +G S+T+ QF P + TG + + Q
Sbjct: 244 AAGSCDKIIRVWCLRTCAPVAVLQGHTG-SITSLQFSPMAKGSQRYMVSTGADGTVCFWQ 302
Query: 366 VKIWDLKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ LK F P + SFS G +LAT + D ++++ L K
Sbjct: 303 WDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIA 362
Query: 423 QLEEN 427
+LE +
Sbjct: 363 ELESH 367
Score = 35.5 bits (78), Expect = 0.43
Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 2/73 (2%)
Query: 215 PGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVI 273
P + + N +D S ++T ND V+N T Q++ L GH +V + HP D ++
Sbjct: 427 PKVTMIAWNQND-SIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIML 485
Query: 274 TASPDHTIRVWNV 286
+A D +I +W++
Sbjct: 486 SAGHDGSIFIWDI 498
>L02547-1|AAA35691.1| 431|Homo sapiens cleavage stimulation factor
protein.
Length = 431
Score = 73.7 bits (173), Expect = 1e-12
Identities = 43/177 (24%), Positives = 86/177 (48%), Gaps = 6/177 (3%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV--WNVPTSQTTAILRSHDG 300
N + V+ L H +VT + +HP E + + S D+T+++ ++ P+++
Sbjct: 159 NMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAE 218
Query: 301 PVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGVSLTTAQFHPDGLIFG 358
+ +S HP+GD++L + DI T Q + D ++ + ++ ++
Sbjct: 219 MLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278
Query: 359 TGTENSQVKIWDLKEQSNVANF-PGHVG-PVTSISFSENGYYLATAAEDSCVKLWDL 413
TG+++ +K+WD + F H G V S FS+N Y+ ++ +DS KLW++
Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
Score = 39.1 bits (87), Expect = 0.035
Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 31/177 (17%)
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKE-----------------QSNVANFP------GHV 384
A + DG + TG+ ++ +KI D + Q N+ N P HV
Sbjct: 114 ATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHV 173
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGTYLA 443
VT ++F LA+ + D +KL+D K + + ++E ++ + F SG ++
Sbjct: 174 DEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFI- 232
Query: 444 IAGTD---VRVYLCRQWQELKVFN---DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ GT +R+Y +Q N HT + V + +A + S D +KL+
Sbjct: 233 LVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLW 289
Score = 39.1 bits (87), Expect = 0.035
Identities = 34/160 (21%), Positives = 70/160 (43%), Gaps = 8/160 (5%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFP--GHVGPVTSISFSENGYYLATA 402
+T FHP I +G+ + +K++D + S F + SISF +G ++
Sbjct: 176 VTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVG 235
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQ 458
+ ++L+D+ + F + ++ + AI + ++ S D ++++ +
Sbjct: 236 TQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNR 295
Query: 459 ELKVFND-HT-ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ F H A F KN++Y+ S+ D KL+ I
Sbjct: 296 CITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
>BT007138-1|AAP35802.1| 431|Homo sapiens cleavage stimulation
factor, 3' pre-RNA, subunit 1, 50kDa protein.
Length = 431
Score = 73.7 bits (173), Expect = 1e-12
Identities = 43/177 (24%), Positives = 86/177 (48%), Gaps = 6/177 (3%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV--WNVPTSQTTAILRSHDG 300
N + V+ L H +VT + +HP E + + S D+T+++ ++ P+++
Sbjct: 159 NMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAE 218
Query: 301 PVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGVSLTTAQFHPDGLIFG 358
+ +S HP+GD++L + DI T Q + D ++ + ++ ++
Sbjct: 219 MLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278
Query: 359 TGTENSQVKIWDLKEQSNVANF-PGHVG-PVTSISFSENGYYLATAAEDSCVKLWDL 413
TG+++ +K+WD + F H G V S FS+N Y+ ++ +DS KLW++
Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
Score = 39.1 bits (87), Expect = 0.035
Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 31/177 (17%)
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKE-----------------QSNVANFP------GHV 384
A + DG + TG+ ++ +KI D + Q N+ N P HV
Sbjct: 114 ATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHV 173
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGTYLA 443
VT ++F LA+ + D +KL+D K + + ++E ++ + F SG ++
Sbjct: 174 DEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFI- 232
Query: 444 IAGTD---VRVYLCRQWQELKVFN---DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ GT +R+Y +Q N HT + V + +A + S D +KL+
Sbjct: 233 LVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLW 289
Score = 39.1 bits (87), Expect = 0.035
Identities = 34/160 (21%), Positives = 70/160 (43%), Gaps = 8/160 (5%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFP--GHVGPVTSISFSENGYYLATA 402
+T FHP I +G+ + +K++D + S F + SISF +G ++
Sbjct: 176 VTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVG 235
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQ 458
+ ++L+D+ + F + ++ + AI + ++ S D ++++ +
Sbjct: 236 TQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNR 295
Query: 459 ELKVFND-HT-ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ F H A F KN++Y+ S+ D KL+ I
Sbjct: 296 CITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
>BC010080-1|AAH10080.1| 305|Homo sapiens WD repeat domain 61
protein.
Length = 305
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/233 (23%), Positives = 99/233 (42%), Gaps = 6/233 (2%)
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTA--ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAF 325
+ +TV+T S D ++VW + L H V + + T S+S D H
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 326 SDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG 385
D+ G+ + + D V T F PD TGT +V I+ ++ +
Sbjct: 91 WDLENGKQIKSI-DAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGK 149
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+ SI++S +G YLA+ A D + ++D+ K T++ I+ L F L A
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLE-GHAMPIRSLTFSPDSQLLVTA 208
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
D +++Y + + H + V F + + S+S D+++K++ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDV 261
Score = 70.1 bits (164), Expect = 2e-11
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 1/187 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D L TG + +F ++ + L K + + Y PD + + + D I +++
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFD 176
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+ T + L H P+ L+ P +++ S D + D++ L +S + L
Sbjct: 177 IATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVL 236
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
A F PD F + + + VK+WD+ ++ V F H V + ++ NG + + +D
Sbjct: 237 NVA-FCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 406 SCVKLWD 412
+ ++D
Sbjct: 296 QEIHIYD 302
Score = 67.7 bits (158), Expect = 9e-11
Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 8/246 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHD-GPVTG--LSLHP 309
L+GH V V ++S D IR+W++ + ++S D GPV L+ P
Sbjct: 60 LEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQ---IKSIDAGPVDAWTLAFSP 116
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
Y+ + + + +G+ + D G + + + PDG +G + + I+
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSL-DTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D+ + GH P+ S++FS + L TA++D +K++D++ T+ ++
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 430 IK-ELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ C D + + + V+V+ + F DH GV++ N + S D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 489 RTLKLY 494
+ + +Y
Sbjct: 296 QEIHIY 301
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
ILS+ +P D L +G D +F+ T +++ L+GH + + + PD ++TAS
Sbjct: 151 ILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
D I++++V + L H V ++ P + +S+SSD+ D+ T
Sbjct: 210 DDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGT 263
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SL +P D L+T +D +++ + L GH V V + PD+ +++S
Sbjct: 193 IRSLTFSP-DSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSS 251
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQ 321
D +++VW+V T H V G+ + G ++S DQ
Sbjct: 252 SDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQ 296
>BC007425-1|AAH07425.1| 431|Homo sapiens cleavage stimulation
factor, 3' pre-RNA, subunit 1, 50kDa protein.
Length = 431
Score = 73.7 bits (173), Expect = 1e-12
Identities = 43/177 (24%), Positives = 86/177 (48%), Gaps = 6/177 (3%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV--WNVPTSQTTAILRSHDG 300
N + V+ L H +VT + +HP E + + S D+T+++ ++ P+++
Sbjct: 159 NMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAE 218
Query: 301 PVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGVSLTTAQFHPDGLIFG 358
+ +S HP+GD++L + DI T Q + D ++ + ++ ++
Sbjct: 219 MLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278
Query: 359 TGTENSQVKIWDLKEQSNVANF-PGHVG-PVTSISFSENGYYLATAAEDSCVKLWDL 413
TG+++ +K+WD + F H G V S FS+N Y+ ++ +DS KLW++
Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
Score = 39.1 bits (87), Expect = 0.035
Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 31/177 (17%)
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKE-----------------QSNVANFP------GHV 384
A + DG + TG+ ++ +KI D + Q N+ N P HV
Sbjct: 114 ATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHV 173
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGTYLA 443
VT ++F LA+ + D +KL+D K + + ++E ++ + F SG ++
Sbjct: 174 DEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFI- 232
Query: 444 IAGTD---VRVYLCRQWQELKVFN---DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ GT +R+Y +Q N HT + V + +A + S D +KL+
Sbjct: 233 LVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLW 289
Score = 39.1 bits (87), Expect = 0.035
Identities = 34/160 (21%), Positives = 70/160 (43%), Gaps = 8/160 (5%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFP--GHVGPVTSISFSENGYYLATA 402
+T FHP I +G+ + +K++D + S F + SISF +G ++
Sbjct: 176 VTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVG 235
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQ 458
+ ++L+D+ + F + ++ + AI + ++ S D ++++ +
Sbjct: 236 TQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNR 295
Query: 459 ELKVFND-HT-ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ F H A F KN++Y+ S+ D KL+ I
Sbjct: 296 CITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
>BC001011-1|AAH01011.1| 431|Homo sapiens cleavage stimulation
factor, 3' pre-RNA, subunit 1, 50kDa protein.
Length = 431
Score = 73.7 bits (173), Expect = 1e-12
Identities = 43/177 (24%), Positives = 86/177 (48%), Gaps = 6/177 (3%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV--WNVPTSQTTAILRSHDG 300
N + V+ L H +VT + +HP E + + S D+T+++ ++ P+++
Sbjct: 159 NMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAE 218
Query: 301 PVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGVSLTTAQFHPDGLIFG 358
+ +S HP+GD++L + DI T Q + D ++ + ++ ++
Sbjct: 219 MLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278
Query: 359 TGTENSQVKIWDLKEQSNVANF-PGHVG-PVTSISFSENGYYLATAAEDSCVKLWDL 413
TG+++ +K+WD + F H G V S FS+N Y+ ++ +DS KLW++
Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
Score = 39.1 bits (87), Expect = 0.035
Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 31/177 (17%)
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKE-----------------QSNVANFP------GHV 384
A + DG + TG+ ++ +KI D + Q N+ N P HV
Sbjct: 114 ATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHV 173
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGTYLA 443
VT ++F LA+ + D +KL+D K + + ++E ++ + F SG ++
Sbjct: 174 DEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFI- 232
Query: 444 IAGTD---VRVYLCRQWQELKVFN---DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ GT +R+Y +Q N HT + V + +A + S D +KL+
Sbjct: 233 LVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLW 289
Score = 39.1 bits (87), Expect = 0.035
Identities = 34/160 (21%), Positives = 70/160 (43%), Gaps = 8/160 (5%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFP--GHVGPVTSISFSENGYYLATA 402
+T FHP I +G+ + +K++D + S F + SISF +G ++
Sbjct: 176 VTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVG 235
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQ 458
+ ++L+D+ + F + ++ + AI + ++ S D ++++ +
Sbjct: 236 TQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNR 295
Query: 459 ELKVFND-HT-ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ F H A F KN++Y+ S+ D KL+ I
Sbjct: 296 CITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
>AL121914-12|CAI19328.1| 431|Homo sapiens cleavage stimulation
factor, 3' pre-RNA, subunit 1, 50kDa protein.
Length = 431
Score = 73.7 bits (173), Expect = 1e-12
Identities = 43/177 (24%), Positives = 86/177 (48%), Gaps = 6/177 (3%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV--WNVPTSQTTAILRSHDG 300
N + V+ L H +VT + +HP E + + S D+T+++ ++ P+++
Sbjct: 159 NMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAE 218
Query: 301 PVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGVSLTTAQFHPDGLIFG 358
+ +S HP+GD++L + DI T Q + D ++ + ++ ++
Sbjct: 219 MLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278
Query: 359 TGTENSQVKIWDLKEQSNVANF-PGHVG-PVTSISFSENGYYLATAAEDSCVKLWDL 413
TG+++ +K+WD + F H G V S FS+N Y+ ++ +DS KLW++
Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
Score = 39.1 bits (87), Expect = 0.035
Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 31/177 (17%)
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKE-----------------QSNVANFP------GHV 384
A + DG + TG+ ++ +KI D + Q N+ N P HV
Sbjct: 114 ATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHV 173
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGTYLA 443
VT ++F LA+ + D +KL+D K + + ++E ++ + F SG ++
Sbjct: 174 DEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFI- 232
Query: 444 IAGTD---VRVYLCRQWQELKVFN---DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ GT +R+Y +Q N HT + V + +A + S D +KL+
Sbjct: 233 LVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLW 289
Score = 39.1 bits (87), Expect = 0.035
Identities = 34/160 (21%), Positives = 70/160 (43%), Gaps = 8/160 (5%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFP--GHVGPVTSISFSENGYYLATA 402
+T FHP I +G+ + +K++D + S F + SISF +G ++
Sbjct: 176 VTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVG 235
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQ 458
+ ++L+D+ + F + ++ + AI + ++ S D ++++ +
Sbjct: 236 TQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNR 295
Query: 459 ELKVFND-HT-ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ F H A F KN++Y+ S+ D KL+ I
Sbjct: 296 CITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
>AL121914-11|CAC12718.2| 345|Homo sapiens cleavage stimulation
factor, 3' pre-RNA, subunit 1, 50kDa protein.
Length = 345
Score = 73.7 bits (173), Expect = 1e-12
Identities = 43/177 (24%), Positives = 86/177 (48%), Gaps = 6/177 (3%)
Query: 243 NKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRV--WNVPTSQTTAILRSHDG 300
N + V+ L H +VT + +HP E + + S D+T+++ ++ P+++
Sbjct: 159 NMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAE 218
Query: 301 PVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVS--DFSGVSLTTAQFHPDGLIFG 358
+ +S HP+GD++L + DI T Q + D ++ + ++ ++
Sbjct: 219 MLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYV 278
Query: 359 TGTENSQVKIWDLKEQSNVANF-PGHVG-PVTSISFSENGYYLATAAEDSCVKLWDL 413
TG+++ +K+WD + F H G V S FS+N Y+ ++ +DS KLW++
Sbjct: 279 TGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
Score = 39.1 bits (87), Expect = 0.035
Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 31/177 (17%)
Query: 348 AQFHPDGLIFGTGTENSQVKIWDLKE-----------------QSNVANFP------GHV 384
A + DG + TG+ ++ +KI D + Q N+ N P HV
Sbjct: 114 ATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHV 173
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGTYLA 443
VT ++F LA+ + D +KL+D K + + ++E ++ + F SG ++
Sbjct: 174 DEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFI- 232
Query: 444 IAGTD---VRVYLCRQWQELKVFN---DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+ GT +R+Y +Q N HT + V + +A + S D +KL+
Sbjct: 233 LVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLW 289
Score = 39.1 bits (87), Expect = 0.035
Identities = 34/160 (21%), Positives = 70/160 (43%), Gaps = 8/160 (5%)
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFP--GHVGPVTSISFSENGYYLATA 402
+T FHP I +G+ + +K++D + S F + SISF +G ++
Sbjct: 176 VTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVG 235
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENY--AIKELCFDQSGTYLAIAGTD--VRVYLCRQWQ 458
+ ++L+D+ + F + ++ + AI + ++ S D ++++ +
Sbjct: 236 TQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNSSANMYVTGSKDGCIKLWDGVSNR 295
Query: 459 ELKVFND-HT-ASATGVRFGKNAQYLASTSMDRTLKLYGI 496
+ F H A F KN++Y+ S+ D KL+ I
Sbjct: 296 CITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEI 335
>AK024754-1|BAB14986.1| 305|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21101 fis, clone CAS04682. ).
Length = 305
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/233 (23%), Positives = 99/233 (42%), Gaps = 6/233 (2%)
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTA--ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAF 325
+ +TV+T S D ++VW + L H V + + T S+S D H
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 326 SDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG 385
D+ G+ + + D V T F PD TGT +V I+ ++ +
Sbjct: 91 WDLENGKQIKSI-DAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGK 149
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+ SI++S +G YLA+ A D + ++D+ K T++ I+ L F L A
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLE-GHAMPIRSLTFSPDSQLLVTA 208
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
D +++Y + + H + V F + + S+S D+++K++ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDV 261
Score = 70.1 bits (164), Expect = 2e-11
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 1/187 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D L TG + +F ++ + L K + + Y PD + + + D I +++
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFD 176
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+ T + L H P+ L+ P +++ S D + D++ L +S + L
Sbjct: 177 IATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVL 236
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
A F PD F + + + VK+WD+ ++ V F H V + ++ NG + + +D
Sbjct: 237 NVA-FCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 406 SCVKLWD 412
+ ++D
Sbjct: 296 QEIHIYD 302
Score = 67.7 bits (158), Expect = 9e-11
Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 8/246 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHD-GPVTG--LSLHP 309
L+GH V V ++S D IR+W++ + ++S D GPV L+ P
Sbjct: 60 LEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQ---IKSIDAGPVDAWTLAFSP 116
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
Y+ + + + +G+ + D G + + + PDG +G + + I+
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSL-DTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D+ + GH P+ S++FS + L TA++D +K++D++ T+ ++
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 430 IK-ELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ C D + + + V+V+ + F DH GV++ N + S D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 489 RTLKLY 494
+ + +Y
Sbjct: 296 QEIHIY 301
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
ILS+ +P D L +G D +F+ T +++ L+GH + + + PD ++TAS
Sbjct: 151 ILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
D I++++V + L H V ++ P + +S+SSD+ D+ T
Sbjct: 210 DDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGT 263
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SL +P D L+T +D +++ + L GH V V + PD+ +++S
Sbjct: 193 IRSLTFSP-DSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSS 251
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQ 321
D +++VW+V T H V G+ + G ++S DQ
Sbjct: 252 SDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQ 296
>AF309553-1|AAG31639.1| 305|Homo sapiens meiotic recombination
protein REC14 protein.
Length = 305
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/233 (23%), Positives = 99/233 (42%), Gaps = 6/233 (2%)
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTA--ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAF 325
+ +TV+T S D ++VW + L H V + + T S+S D H
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 326 SDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG 385
D+ G+ + + D V T F PD TGT +V I+ ++ +
Sbjct: 91 WDLENGKQIKSI-DAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGK 149
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+ SI++S +G YLA+ A D + ++D+ K T++ I+ L F L A
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLE-GHAMPIRSLTFSPDSQLLVTA 208
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
D +++Y + + H + V F + + S+S D+++K++ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDV 261
Score = 70.1 bits (164), Expect = 2e-11
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 1/187 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D L TG + +F ++ + L K + + Y PD + + + D I +++
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFD 176
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+ T + L H P+ L+ P +++ S D + D++ L +S + L
Sbjct: 177 IATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVL 236
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
A F PD F + + + VK+WD+ ++ V F H V + ++ NG + + +D
Sbjct: 237 NVA-FCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 406 SCVKLWD 412
+ ++D
Sbjct: 296 QEIHIYD 302
Score = 67.7 bits (158), Expect = 9e-11
Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 8/246 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHD-GPVTG--LSLHP 309
L+GH V V ++S D IR+W++ + ++S D GPV L+ P
Sbjct: 60 LEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQ---IKSIDAGPVDAWTLAFSP 116
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
Y+ + + + +G+ + D G + + + PDG +G + + I+
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSL-DTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D+ + GH P+ S++FS + L TA++D +K++D++ T+ ++
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 430 IK-ELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ C D + + + V+V+ + F DH GV++ N + S D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 489 RTLKLY 494
+ + +Y
Sbjct: 296 QEIHIY 301
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
ILS+ +P D L +G D +F+ T +++ L+GH + + + PD ++TAS
Sbjct: 151 ILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
D I++++V + L H V ++ P + +S+SSD+ D+ T
Sbjct: 210 DDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGT 263
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SL +P D L+T +D +++ + L GH V V + PD+ +++S
Sbjct: 193 IRSLTFSP-DSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSS 251
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQ 321
D +++VW+V T H V G+ + G ++S DQ
Sbjct: 252 SDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQ 296
>AF100786-1|AAP97225.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 73.7 bits (173), Expect = 1e-12
Identities = 54/233 (23%), Positives = 99/233 (42%), Gaps = 6/233 (2%)
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTA--ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAF 325
+ +TV+T S D ++VW + L H V + + T S+S D H
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 326 SDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG 385
D+ G+ + + D V T F PD TGT +V I+ ++ +
Sbjct: 91 WDLENGKQIKSI-DAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGK 149
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+ SI++S +G YLA+ A D + ++D+ K T++ I+ L F L A
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLE-GHAMPIRSLTFSPDSQLLVTA 208
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
D +++Y + + H + V F + + S+S D+++K++ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDV 261
Score = 70.1 bits (164), Expect = 2e-11
Identities = 41/187 (21%), Positives = 82/187 (43%), Gaps = 1/187 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D L TG + +F ++ + L K + + Y PD + + + D I +++
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFD 176
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+ T + L H P+ L+ P +++ S D + D++ L +S + L
Sbjct: 177 IATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVL 236
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
A F PD F + + + VK+WD+ ++ V F H V + ++ NG + + +D
Sbjct: 237 NVA-FCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 406 SCVKLWD 412
+ ++D
Sbjct: 296 QEIHIYD 302
Score = 67.7 bits (158), Expect = 9e-11
Identities = 53/246 (21%), Positives = 106/246 (43%), Gaps = 8/246 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHD-GPVTG--LSLHP 309
L+GH V V ++S D IR+W++ + ++S D GPV L+ P
Sbjct: 60 LEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQ---IKSIDAGPVDAWTLAFSP 116
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
Y+ + + + +G+ + D G + + + PDG +G + + I+
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSL-DTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D+ + GH P+ S++FS + L TA++D +K++D++ T+ ++
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 430 IK-ELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ C D + + + V+V+ + F DH GV++ N + S D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 489 RTLKLY 494
+ + +Y
Sbjct: 296 QEIHIY 301
Score = 53.6 bits (123), Expect = 2e-06
Identities = 31/114 (27%), Positives = 57/114 (50%), Gaps = 1/114 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
ILS+ +P D L +G D +F+ T +++ L+GH + + + PD ++TAS
Sbjct: 151 ILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
D I++++V + L H V ++ P + +S+SSD+ D+ T
Sbjct: 210 DDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGT 263
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 1/105 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SL +P D L+T +D +++ + L GH V V + PD+ +++S
Sbjct: 193 IRSLTFSP-DSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSS 251
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQ 321
D +++VW+V T H V G+ + G ++S DQ
Sbjct: 252 SDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQ 296
>BC111490-1|AAI11491.1| 768|Homo sapiens BRWD3 protein protein.
Length = 768
Score = 73.3 bits (172), Expect = 2e-12
Identities = 47/212 (22%), Positives = 99/212 (46%), Gaps = 16/212 (7%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH+ +++ + + + + S D +RVW + T
Sbjct: 194 RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRT 253
Query: 289 SQTTAILRSHDGPVTGLSLHP----TGDYVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H +T + P T Y+ ST +D W ++ K ++
Sbjct: 254 CAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTE 313
Query: 340 FS--GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ--SNVANFPGHVGPVTSISFSEN 395
S GV ++ + F G+ TG+ + ++I+ L + +A H V ++ F N
Sbjct: 314 RSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNN 373
Query: 396 GYYL--ATAAEDSCVKLWDLRKLKNFKTIQLE 425
G L + + D ++W ++ + +K+I L+
Sbjct: 374 GDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLD 404
Score = 41.9 bits (94), Expect = 0.005
Identities = 38/185 (20%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + S S+T+ QF P + + TG + + Q
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHS-ASITSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Query: 366 VKIWDLKEQSNVANFPGHVGP---VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ +K + F P ++ SFS G ++ T + D ++++ L K
Sbjct: 297 WHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIA 356
Query: 423 QLEEN 427
+LE +
Sbjct: 357 ELESH 361
Score = 40.7 bits (91), Expect = 0.012
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD-YVLST 317
KVT V + + TVITA + ++VWN T Q L HD V L HP +LS
Sbjct: 425 KVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSA 484
Query: 318 SSDQHWAFSDIRTGQLLTKVSDF 340
D + D+ G TK+ ++
Sbjct: 485 GHDGNIFIWDLDRG---TKIRNY 504
Score = 39.5 bits (88), Expect = 0.027
Identities = 35/164 (21%), Positives = 63/164 (38%), Gaps = 13/164 (7%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 182 SVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGS 241
Query: 404 EDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGT--YLAIAGTDVRVYLCRQWQEL 460
D V++W LR +Q + + C GT YL G D + + +
Sbjct: 242 CDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKT 301
Query: 461 KVFNDHTASAT-----GVR-----FGKNAQYLASTSMDRTLKLY 494
F D T GV+ F ++ + S D +++Y
Sbjct: 302 MKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIY 345
Score = 33.5 bits (73), Expect = 1.8
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ L GH +V + HP D+ +++A D I +W++
Sbjct: 438 VITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDR 497
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
+ I G V P G++ T S H + K+ D
Sbjct: 498 GTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPD 553
Score = 31.9 bits (69), Expect = 5.3
Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 15/164 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD---EDTVITAS-PDHTI 281
+++ + G D+ V+ T VA+L+GH+ +T + + P + +T++ D TI
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTI 292
Query: 282 RV--WNVPTSQ-----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLL 334
W+V T + RS G S +G ++T S H ++
Sbjct: 293 CFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVP 352
Query: 335 TKVSDFSGVS--LTTAQF--HPDGLIFGTGTENSQVKIWDLKEQ 374
K+++ + + QF + D L F +G+ + +IW ++Q
Sbjct: 353 EKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQ 396
>AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repeat
domain containing 3 variant BRWD3-B protein.
Length = 1631
Score = 73.3 bits (172), Expect = 2e-12
Identities = 47/212 (22%), Positives = 99/212 (46%), Gaps = 16/212 (7%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH+ +++ + + + + S D +RVW + T
Sbjct: 23 RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRT 82
Query: 289 SQTTAILRSHDGPVTGLSLHP----TGDYVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H +T + P T Y+ ST +D W ++ K ++
Sbjct: 83 CAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTE 142
Query: 340 FS--GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ--SNVANFPGHVGPVTSISFSEN 395
S GV ++ + F G+ TG+ + ++I+ L + +A H V ++ F N
Sbjct: 143 RSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNN 202
Query: 396 GYYL--ATAAEDSCVKLWDLRKLKNFKTIQLE 425
G L + + D ++W ++ + +K+I L+
Sbjct: 203 GDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLD 233
Score = 41.9 bits (94), Expect = 0.005
Identities = 38/185 (20%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 7 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 66
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + S S+T+ QF P + + TG + + Q
Sbjct: 67 AAGSCDKVVRVWCLRTCAPVAVLQGHS-ASITSIQFCPSTKGTNRYLTSTGADGTICFWQ 125
Query: 366 VKIWDLKEQSNVANFPGHVGP---VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ +K + F P ++ SFS G ++ T + D ++++ L K
Sbjct: 126 WHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIA 185
Query: 423 QLEEN 427
+LE +
Sbjct: 186 ELESH 190
Score = 40.7 bits (91), Expect = 0.012
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD-YVLST 317
KVT V + + TVITA + ++VWN T Q L HD V L HP +LS
Sbjct: 254 KVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSA 313
Query: 318 SSDQHWAFSDIRTGQLLTKVSDF 340
D + D+ G TK+ ++
Sbjct: 314 GHDGNIFIWDLDRG---TKIRNY 333
Score = 39.5 bits (88), Expect = 0.027
Identities = 35/164 (21%), Positives = 63/164 (38%), Gaps = 13/164 (7%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 11 SVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGS 70
Query: 404 EDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGT--YLAIAGTDVRVYLCRQWQEL 460
D V++W LR +Q + + C GT YL G D + + +
Sbjct: 71 CDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKT 130
Query: 461 KVFNDHTASAT-----GVR-----FGKNAQYLASTSMDRTLKLY 494
F D T GV+ F ++ + S D +++Y
Sbjct: 131 MKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIY 174
Score = 33.5 bits (73), Expect = 1.8
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ L GH +V + HP D+ +++A D I +W++
Sbjct: 267 VITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDR 326
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
+ I G V P G++ T S H + K+ D
Sbjct: 327 GTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPD 382
Score = 31.9 bits (69), Expect = 5.3
Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 15/164 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD---EDTVITAS-PDHTI 281
+++ + G D+ V+ T VA+L+GH+ +T + + P + +T++ D TI
Sbjct: 62 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTI 121
Query: 282 RV--WNVPTSQ-----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLL 334
W+V T + RS G S +G ++T S H ++
Sbjct: 122 CFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVP 181
Query: 335 TKVSDFSGVS--LTTAQF--HPDGLIFGTGTENSQVKIWDLKEQ 374
K+++ + + QF + D L F +G+ + +IW ++Q
Sbjct: 182 EKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQ 225
>AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 variant BRWD3-A protein.
Length = 1802
Score = 73.3 bits (172), Expect = 2e-12
Identities = 47/212 (22%), Positives = 99/212 (46%), Gaps = 16/212 (7%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH+ +++ + + + + S D +RVW + T
Sbjct: 194 RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRT 253
Query: 289 SQTTAILRSHDGPVTGLSLHP----TGDYVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H +T + P T Y+ ST +D W ++ K ++
Sbjct: 254 CAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTE 313
Query: 340 FS--GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ--SNVANFPGHVGPVTSISFSEN 395
S GV ++ + F G+ TG+ + ++I+ L + +A H V ++ F N
Sbjct: 314 RSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNN 373
Query: 396 GYYL--ATAAEDSCVKLWDLRKLKNFKTIQLE 425
G L + + D ++W ++ + +K+I L+
Sbjct: 374 GDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLD 404
Score = 41.9 bits (94), Expect = 0.005
Identities = 38/185 (20%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + S S+T+ QF P + + TG + + Q
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHS-ASITSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Query: 366 VKIWDLKEQSNVANFPGHVGP---VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ +K + F P ++ SFS G ++ T + D ++++ L K
Sbjct: 297 WHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIA 356
Query: 423 QLEEN 427
+LE +
Sbjct: 357 ELESH 361
Score = 40.7 bits (91), Expect = 0.012
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD-YVLST 317
KVT V + + TVITA + ++VWN T Q L HD V L HP +LS
Sbjct: 425 KVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSA 484
Query: 318 SSDQHWAFSDIRTGQLLTKVSDF 340
D + D+ G TK+ ++
Sbjct: 485 GHDGNIFIWDLDRG---TKIRNY 504
Score = 39.5 bits (88), Expect = 0.027
Identities = 35/164 (21%), Positives = 63/164 (38%), Gaps = 13/164 (7%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 182 SVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGS 241
Query: 404 EDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGT--YLAIAGTDVRVYLCRQWQEL 460
D V++W LR +Q + + C GT YL G D + + +
Sbjct: 242 CDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKT 301
Query: 461 KVFNDHTASAT-----GVR-----FGKNAQYLASTSMDRTLKLY 494
F D T GV+ F ++ + S D +++Y
Sbjct: 302 MKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIY 345
Score = 33.5 bits (73), Expect = 1.8
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ L GH +V + HP D+ +++A D I +W++
Sbjct: 438 VITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDR 497
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
+ I G V P G++ T S H + K+ D
Sbjct: 498 GTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPD 553
Score = 31.9 bits (69), Expect = 5.3
Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 15/164 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD---EDTVITAS-PDHTI 281
+++ + G D+ V+ T VA+L+GH+ +T + + P + +T++ D TI
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTI 292
Query: 282 RV--WNVPTSQ-----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLL 334
W+V T + RS G S +G ++T S H ++
Sbjct: 293 CFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVP 352
Query: 335 TKVSDFSGVS--LTTAQF--HPDGLIFGTGTENSQVKIWDLKEQ 374
K+++ + + QF + D L F +G+ + +IW ++Q
Sbjct: 353 EKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQ 396
>AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 73.3 bits (172), Expect = 2e-12
Identities = 47/212 (22%), Positives = 99/212 (46%), Gaps = 16/212 (7%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH+ +++ + + + + S D +RVW + T
Sbjct: 194 RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRT 253
Query: 289 SQTTAILRSHDGPVTGLSLHP----TGDYVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H +T + P T Y+ ST +D W ++ K ++
Sbjct: 254 CAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTE 313
Query: 340 FS--GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ--SNVANFPGHVGPVTSISFSEN 395
S GV ++ + F G+ TG+ + ++I+ L + +A H V ++ F N
Sbjct: 314 RSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNN 373
Query: 396 GYYL--ATAAEDSCVKLWDLRKLKNFKTIQLE 425
G L + + D ++W ++ + +K+I L+
Sbjct: 374 GDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLD 404
Score = 41.9 bits (94), Expect = 0.005
Identities = 38/185 (20%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + S S+T+ QF P + + TG + + Q
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHS-ASITSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Query: 366 VKIWDLKEQSNVANFPGHVGP---VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ +K + F P ++ SFS G ++ T + D ++++ L K
Sbjct: 297 WHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIA 356
Query: 423 QLEEN 427
+LE +
Sbjct: 357 ELESH 361
Score = 40.7 bits (91), Expect = 0.012
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD-YVLST 317
KVT V + + TVITA + ++VWN T Q L HD V L HP +LS
Sbjct: 425 KVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSA 484
Query: 318 SSDQHWAFSDIRTGQLLTKVSDF 340
D + D+ G TK+ ++
Sbjct: 485 GHDGNIFIWDLDRG---TKIRNY 504
Score = 39.5 bits (88), Expect = 0.027
Identities = 35/164 (21%), Positives = 63/164 (38%), Gaps = 13/164 (7%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 182 SVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGS 241
Query: 404 EDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGT--YLAIAGTDVRVYLCRQWQEL 460
D V++W LR +Q + + C GT YL G D + + +
Sbjct: 242 CDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKT 301
Query: 461 KVFNDHTASAT-----GVR-----FGKNAQYLASTSMDRTLKLY 494
F D T GV+ F ++ + S D +++Y
Sbjct: 302 MKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIY 345
Score = 33.5 bits (73), Expect = 1.8
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ L GH +V + HP D+ +++A D I +W++
Sbjct: 438 VITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDR 497
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
+ I G V P G++ T S H + K+ D
Sbjct: 498 GTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPD 553
Score = 31.9 bits (69), Expect = 5.3
Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 15/164 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD---EDTVITAS-PDHTI 281
+++ + G D+ V+ T VA+L+GH+ +T + + P + +T++ D TI
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTI 292
Query: 282 RV--WNVPTSQ-----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLL 334
W+V T + RS G S +G ++T S H ++
Sbjct: 293 CFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVP 352
Query: 335 TKVSDFSGVS--LTTAQF--HPDGLIFGTGTENSQVKIWDLKEQ 374
K+++ + + QF + D L F +G+ + +IW ++Q
Sbjct: 353 EKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQ 396
>AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 73.3 bits (172), Expect = 2e-12
Identities = 47/212 (22%), Positives = 99/212 (46%), Gaps = 16/212 (7%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH+ +++ + + + + S D +RVW + T
Sbjct: 194 RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRT 253
Query: 289 SQTTAILRSHDGPVTGLSLHP----TGDYVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H +T + P T Y+ ST +D W ++ K ++
Sbjct: 254 CAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTE 313
Query: 340 FS--GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ--SNVANFPGHVGPVTSISFSEN 395
S GV ++ + F G+ TG+ + ++I+ L + +A H V ++ F N
Sbjct: 314 RSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNN 373
Query: 396 GYYL--ATAAEDSCVKLWDLRKLKNFKTIQLE 425
G L + + D ++W ++ + +K+I L+
Sbjct: 374 GDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLD 404
Score = 41.9 bits (94), Expect = 0.005
Identities = 38/185 (20%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + S S+T+ QF P + + TG + + Q
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHS-ASITSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Query: 366 VKIWDLKEQSNVANFPGHVGP---VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ +K + F P ++ SFS G ++ T + D ++++ L K
Sbjct: 297 WHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIA 356
Query: 423 QLEEN 427
+LE +
Sbjct: 357 ELESH 361
Score = 40.7 bits (91), Expect = 0.012
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD-YVLST 317
KVT V + + TVITA + ++VWN T Q L HD V L HP +LS
Sbjct: 425 KVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSA 484
Query: 318 SSDQHWAFSDIRTGQLLTKVSDF 340
D + D+ G TK+ ++
Sbjct: 485 GHDGNIFIWDLDRG---TKIRNY 504
Score = 39.5 bits (88), Expect = 0.027
Identities = 35/164 (21%), Positives = 63/164 (38%), Gaps = 13/164 (7%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 182 SVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGS 241
Query: 404 EDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGT--YLAIAGTDVRVYLCRQWQEL 460
D V++W LR +Q + + C GT YL G D + + +
Sbjct: 242 CDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKT 301
Query: 461 KVFNDHTASAT-----GVR-----FGKNAQYLASTSMDRTLKLY 494
F D T GV+ F ++ + S D +++Y
Sbjct: 302 MKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIY 345
Score = 33.5 bits (73), Expect = 1.8
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ L GH +V + HP D+ +++A D I +W++
Sbjct: 438 VITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDR 497
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
+ I G V P G++ T S H + K+ D
Sbjct: 498 GTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPD 553
Score = 31.9 bits (69), Expect = 5.3
Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 15/164 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD---EDTVITAS-PDHTI 281
+++ + G D+ V+ T VA+L+GH+ +T + + P + +T++ D TI
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTI 292
Query: 282 RV--WNVPTSQ-----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLL 334
W+V T + RS G S +G ++T S H ++
Sbjct: 293 CFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVP 352
Query: 335 TKVSDFSGVS--LTTAQF--HPDGLIFGTGTENSQVKIWDLKEQ 374
K+++ + + QF + D L F +G+ + +IW ++Q
Sbjct: 353 EKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQ 396
>AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repeat
domain containing 3 protein.
Length = 1802
Score = 73.3 bits (172), Expect = 2e-12
Identities = 47/212 (22%), Positives = 99/212 (46%), Gaps = 16/212 (7%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH+ +++ + + + + S D +RVW + T
Sbjct: 194 RIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRT 253
Query: 289 SQTTAILRSHDGPVTGLSLHP----TGDYVLSTSSD-----QHWAFSDIRTGQLLTKVSD 339
A+L+ H +T + P T Y+ ST +D W ++ K ++
Sbjct: 254 CAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTE 313
Query: 340 FS--GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ--SNVANFPGHVGPVTSISFSEN 395
S GV ++ + F G+ TG+ + ++I+ L + +A H V ++ F N
Sbjct: 314 RSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNN 373
Query: 396 GYYL--ATAAEDSCVKLWDLRKLKNFKTIQLE 425
G L + + D ++W ++ + +K+I L+
Sbjct: 374 GDSLRFVSGSRDGTARIWQYQQ-QEWKSIVLD 404
Score = 41.9 bits (94), Expect = 0.005
Identities = 38/185 (20%), Positives = 76/185 (41%), Gaps = 13/185 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS----Q 365
+ S D+ +RT + + S S+T+ QF P + + TG + + Q
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHS-ASITSIQFCPSTKGTNRYLTSTGADGTICFWQ 296
Query: 366 VKIWDLKEQSNVANFPGHVGP---VTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTI 422
+ +K + F P ++ SFS G ++ T + D ++++ L K
Sbjct: 297 WHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIA 356
Query: 423 QLEEN 427
+LE +
Sbjct: 357 ELESH 361
Score = 40.7 bits (91), Expect = 0.012
Identities = 28/83 (33%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD-YVLST 317
KVT V + + TVITA + ++VWN T Q L HD V L HP +LS
Sbjct: 425 KVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSA 484
Query: 318 SSDQHWAFSDIRTGQLLTKVSDF 340
D + D+ G TK+ ++
Sbjct: 485 GHDGNIFIWDLDRG---TKIRNY 504
Score = 39.5 bits (88), Expect = 0.027
Identities = 35/164 (21%), Positives = 63/164 (38%), Gaps = 13/164 (7%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 182 SVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGS 241
Query: 404 EDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCFDQSGT--YLAIAGTDVRVYLCRQWQEL 460
D V++W LR +Q + + C GT YL G D + + +
Sbjct: 242 CDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKT 301
Query: 461 KVFNDHTASAT-----GVR-----FGKNAQYLASTSMDRTLKLY 494
F D T GV+ F ++ + S D +++Y
Sbjct: 302 MKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIY 345
Score = 33.5 bits (73), Expect = 1.8
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ L GH +V + HP D+ +++A D I +W++
Sbjct: 438 VITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDR 497
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
+ I G V P G++ T S H + K+ D
Sbjct: 498 GTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPD 553
Score = 31.9 bits (69), Expect = 5.3
Identities = 36/164 (21%), Positives = 71/164 (43%), Gaps = 15/164 (9%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD---EDTVITAS-PDHTI 281
+++ + G D+ V+ T VA+L+GH+ +T + + P + +T++ D TI
Sbjct: 233 ENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTI 292
Query: 282 RV--WNVPTSQ-----TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLL 334
W+V T + RS G S +G ++T S H ++
Sbjct: 293 CFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVP 352
Query: 335 TKVSDFSGVS--LTTAQF--HPDGLIFGTGTENSQVKIWDLKEQ 374
K+++ + + QF + D L F +G+ + +IW ++Q
Sbjct: 353 EKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQ 396
>CR457333-1|CAG33614.1| 305|Homo sapiens REC14 protein.
Length = 305
Score = 72.9 bits (171), Expect = 2e-12
Identities = 54/233 (23%), Positives = 97/233 (41%), Gaps = 6/233 (2%)
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTA--ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAF 325
+ +TV+T S D ++VW + L H V + + T S+S D H
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 326 SDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG 385
D+ G+ + + D V T F PD TGT +V I+ ++ +
Sbjct: 91 WDLENGKQIKSI-DAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGK 149
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+ SI++S +G YLA+ A D + ++D+ K T++ I+ L F L A
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLE-GHAMPIRSLTFSPDSQLLVTA 208
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGI 496
D +++Y + H + V F + + S+S D+ +K++ +
Sbjct: 209 SDDGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDV 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 40/187 (21%), Positives = 81/187 (43%), Gaps = 1/187 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D L TG + +F ++ + L K + + Y PD + + + D I +++
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFD 176
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+ T + L H P+ L+ P +++ S D + D++ L + + L
Sbjct: 177 IATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWVL 236
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
A F PD F + + + VK+WD+ ++ V F H V + ++ NG + + +D
Sbjct: 237 NVA-FCPDDTHFVSSSSDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 406 SCVKLWD 412
+ ++D
Sbjct: 296 QEIHIYD 302
Score = 67.3 bits (157), Expect = 1e-10
Identities = 53/246 (21%), Positives = 107/246 (43%), Gaps = 8/246 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHD-GPVTG--LSLHP 309
L+GH V V ++S D IR+W++ + ++S D GPV L+ P
Sbjct: 60 LEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQ---IKSIDAGPVDAWTLAFSP 116
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
Y+ + + + +G+ + D G + + + PDG +G + + I+
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSL-DTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D+ + GH P+ S++FS + L TA++D +K++D++ T+ ++
Sbjct: 176 DIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWV 235
Query: 430 IK-ELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ C D + + + +V+V+ + F DH GV++ N + S D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 489 RTLKLY 494
+ + +Y
Sbjct: 296 QEIHIY 301
Score = 54.0 bits (124), Expect = 1e-06
Identities = 31/114 (27%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
ILS+ +P D L +G D +F+ T +++ L+GH + + + PD ++TAS
Sbjct: 151 ILSIAYSP-DGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
D I++++V + L H V ++ P + +S+SSD++ D+ T
Sbjct: 210 DDGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGT 263
Score = 52.4 bits (120), Expect = 4e-06
Identities = 28/105 (26%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SL +P D L+T +D +++ + L GH V V + PD+ +++S
Sbjct: 193 IRSLTFSP-DSQLLVTASDDGYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSS 251
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQ 321
D ++VW+V T H V G+ + G ++S DQ
Sbjct: 252 SDKNVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQ 296
>M24194-1|AAA59626.1| 317|Homo sapiens MHC B complex protein 12.3
protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>EF011612-1|ABK41102.1| 514|Homo sapiens CDW2/WDR26 protein.
Length = 514
Score = 71.3 bits (167), Expect = 7e-12
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 17/283 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTE----QVVAILKGHTKKVTRVIYHPDEDTVITASPD-- 278
+D +KL TG D ++ D + +++ L+GH V+ + + PD++ ++ PD
Sbjct: 218 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDC 277
Query: 279 HTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKV 337
+ +WNV T + T + +SH+ +T ++ +P G ++ + D+ G LL
Sbjct: 278 SELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDL-DGNLL--- 333
Query: 338 SDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY 397
+ GV + DG + +++ ++ ++ ++ N P+ S + S+NG
Sbjct: 334 DSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTD-RNIVQEDHPIMSFTISKNGR 392
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCF-DQSGTYLAIAGTDVRVYLCR 455
V LWDL+ + Q + + + CF + ++A D +VY+
Sbjct: 393 LALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWH 452
Query: 456 QWQELKV--FNDHTASATGVRFGKN-AQYLASTSMDRTLKLYG 495
+ EL + HT + V + +AS S D T++++G
Sbjct: 453 KRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWG 495
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSL--- 307
IL H +V + D + T S D T+ +W V P + +L++ +G G+S
Sbjct: 203 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAW 262
Query: 308 HPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
P +Y+++ D + W ++ ++TG+L TK+S SLT+ ++PDG F TG +
Sbjct: 263 SPDDNYLVACGPDDCSELWLWN-VQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRG 321
Query: 365 QVKIWDL 371
Q DL
Sbjct: 322 QFYQCDL 328
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSN----VANFPGHVGPVTSISFSENGYYLATAAE 404
+F DG TG++++ V IW + ++ + GH V+ I++S + YL
Sbjct: 215 KFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGP 274
Query: 405 DSCVKLW 411
D C +LW
Sbjct: 275 DDCSELW 281
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLW----DLRKLKNFKTIQLEENYAIKELCFDQS 438
H V FS +G LAT ++D+ V +W D LK KT++ Y + + +
Sbjct: 207 HCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLE-GHAYGVSYIAWSPD 265
Query: 439 GTYLAIAGTD 448
YL G D
Sbjct: 266 DNYLVACGPD 275
>CR541909-1|CAG46707.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>CR456978-1|CAG33259.1| 317|Homo sapiens GNB2L1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC063817-1|AAH63817.1| 404|Homo sapiens WDR26 protein protein.
Length = 404
Score = 71.3 bits (167), Expect = 7e-12
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 17/283 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTE----QVVAILKGHTKKVTRVIYHPDEDTVITASPD-- 278
+D +KL TG D ++ D + +++ L+GH V+ + + PD++ ++ PD
Sbjct: 108 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDC 167
Query: 279 HTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKV 337
+ +WNV T + T + +SH+ +T ++ +P G ++ + D+ G LL
Sbjct: 168 SELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDL-DGNLL--- 223
Query: 338 SDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY 397
+ GV + DG + +++ ++ ++ ++ N P+ S + S+NG
Sbjct: 224 DSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTD-RNIVQEDHPIMSFTISKNGR 282
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCF-DQSGTYLAIAGTDVRVYLCR 455
V LWDL+ + Q + + + CF + ++A D +VY+
Sbjct: 283 LALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWH 342
Query: 456 QWQELKV--FNDHTASATGVRFGKN-AQYLASTSMDRTLKLYG 495
+ EL + HT + V + +AS S D T++++G
Sbjct: 343 KRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWG 385
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSL--- 307
IL H +V + D + T S D T+ +W V P + +L++ +G G+S
Sbjct: 93 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAW 152
Query: 308 HPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
P +Y+++ D + W ++ ++TG+L TK+S SLT+ ++PDG F TG +
Sbjct: 153 SPDDNYLVACGPDDCSELWLWN-VQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRG 211
Query: 365 QVKIWDL 371
Q DL
Sbjct: 212 QFYQCDL 218
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSN----VANFPGHVGPVTSISFSENGYYLATAAE 404
+F DG TG++++ V IW + ++ + GH V+ I++S + YL
Sbjct: 105 KFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGP 164
Query: 405 DSCVKLW 411
D C +LW
Sbjct: 165 DDCSELW 171
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLW----DLRKLKNFKTIQLEENYAIKELCFDQS 438
H V FS +G LAT ++D+ V +W D LK KT++ Y + + +
Sbjct: 97 HCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLE-GHAYGVSYIAWSPD 155
Query: 439 GTYLAIAGTD 448
YL G D
Sbjct: 156 DNYLVACGPD 165
>BC052301-1|AAH52301.2| 514|Homo sapiens WD repeat domain 26
protein.
Length = 514
Score = 71.3 bits (167), Expect = 7e-12
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 17/283 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTE----QVVAILKGHTKKVTRVIYHPDEDTVITASPD-- 278
+D +KL TG D ++ D + +++ L+GH V+ + + PD++ ++ PD
Sbjct: 218 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDC 277
Query: 279 HTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKV 337
+ +WNV T + T + +SH+ +T ++ +P G ++ + D+ G LL
Sbjct: 278 SELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDL-DGNLL--- 333
Query: 338 SDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY 397
+ GV + DG + +++ ++ ++ ++ N P+ S + S+NG
Sbjct: 334 DSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTD-RNIVQEDHPIMSFTISKNGR 392
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCF-DQSGTYLAIAGTDVRVYLCR 455
V LWDL+ + Q + + + CF + ++A D +VY+
Sbjct: 393 LALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWH 452
Query: 456 QWQELKV--FNDHTASATGVRFGKN-AQYLASTSMDRTLKLYG 495
+ EL + HT + V + +AS S D T++++G
Sbjct: 453 KRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWG 495
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSL--- 307
IL H +V + D + T S D T+ +W V P + +L++ +G G+S
Sbjct: 203 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAW 262
Query: 308 HPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
P +Y+++ D + W ++ ++TG+L TK+S SLT+ ++PDG F TG +
Sbjct: 263 SPDDNYLVACGPDDCSELWLWN-VQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRG 321
Query: 365 QVKIWDL 371
Q DL
Sbjct: 322 QFYQCDL 328
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSN----VANFPGHVGPVTSISFSENGYYLATAAE 404
+F DG TG++++ V IW + ++ + GH V+ I++S + YL
Sbjct: 215 KFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGP 274
Query: 405 DSCVKLW 411
D C +LW
Sbjct: 275 DDCSELW 281
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLW----DLRKLKNFKTIQLEENYAIKELCFDQS 438
H V FS +G LAT ++D+ V +W D LK KT++ Y + + +
Sbjct: 207 HCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLE-GHAYGVSYIAWSPD 265
Query: 439 GTYLAIAGTD 448
YL G D
Sbjct: 266 DNYLVACGPD 275
>BC032006-1|AAH32006.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC031471-1|AAH31471.2| 373|Homo sapiens WDR26 protein protein.
Length = 373
Score = 71.3 bits (167), Expect = 7e-12
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 17/283 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTE----QVVAILKGHTKKVTRVIYHPDEDTVITASPD-- 278
+D +KL TG D ++ D + +++ L+GH V+ + + PD++ ++ PD
Sbjct: 77 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDC 136
Query: 279 HTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKV 337
+ +WNV T + T + +SH+ +T ++ +P G ++ + D+ G LL
Sbjct: 137 SELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDL-DGNLL--- 192
Query: 338 SDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY 397
+ GV + DG + +++ ++ ++ ++ N P+ S + S+NG
Sbjct: 193 DSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTD-RNIVQEDHPIMSFTISKNGR 251
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCF-DQSGTYLAIAGTDVRVYLCR 455
V LWDL+ + Q + + + CF + ++A D +VY+
Sbjct: 252 LALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWH 311
Query: 456 QWQELKV--FNDHTASATGVRFGKN-AQYLASTSMDRTLKLYG 495
+ EL + HT + V + +AS S D T++++G
Sbjct: 312 KRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWG 354
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSL--- 307
IL H +V + D + T S D T+ +W V P + +L++ +G G+S
Sbjct: 62 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAW 121
Query: 308 HPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
P +Y+++ D + W ++ ++TG+L TK+S SLT+ ++PDG F TG +
Sbjct: 122 SPDDNYLVACGPDDCSELWLWN-VQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRG 180
Query: 365 QVKIWDL 371
Q DL
Sbjct: 181 QFYQCDL 187
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSN----VANFPGHVGPVTSISFSENGYYLATAAE 404
+F DG TG++++ V IW + ++ + GH V+ I++S + YL
Sbjct: 74 KFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGP 133
Query: 405 DSCVKLW 411
D C +LW
Sbjct: 134 DDCSELW 140
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLW----DLRKLKNFKTIQLEENYAIKELCFDQS 438
H V FS +G LAT ++D+ V +W D LK KT++ Y + + +
Sbjct: 66 HCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLE-GHAYGVSYIAWSPD 124
Query: 439 GTYLAIAGTD 448
YL G D
Sbjct: 125 DNYLVACGPD 134
>BC021993-1|AAH21993.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC019362-1|AAH19362.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC019093-1|AAH19093.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC017287-1|AAH17287.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC014788-1|AAH14788.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC014256-1|AAH14256.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC010119-1|AAH10119.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC000366-1|AAH00366.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>BC000214-1|AAH00214.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 protein.
Length = 317
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>AY304473-1|AAQ74770.1| 514|Homo sapiens WD40 repeat protein 26
protein.
Length = 514
Score = 71.3 bits (167), Expect = 7e-12
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 17/283 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTE----QVVAILKGHTKKVTRVIYHPDEDTVITASPD-- 278
+D +KL TG D ++ D + +++ L+GH V+ + + PD++ ++ PD
Sbjct: 218 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDC 277
Query: 279 HTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKV 337
+ +WNV T + T + +SH+ +T ++ +P G ++ + D+ G LL
Sbjct: 278 SELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDL-DGNLL--- 333
Query: 338 SDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY 397
+ GV + DG + +++ ++ ++ ++ N P+ S + S+NG
Sbjct: 334 DSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTD-RNIVQEDHPIMSFTISKNGR 392
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCF-DQSGTYLAIAGTDVRVYLCR 455
V LWDL+ + Q + + + CF + ++A D +VY+
Sbjct: 393 LALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWH 452
Query: 456 QWQELKV--FNDHTASATGVRFGKN-AQYLASTSMDRTLKLYG 495
+ EL + HT + V + +AS S D T++++G
Sbjct: 453 KRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWG 495
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSL--- 307
IL H +V + D + T S D T+ +W V P + +L++ +G G+S
Sbjct: 203 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAW 262
Query: 308 HPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
P +Y+++ D + W ++ ++TG+L TK+S SLT+ ++PDG F TG +
Sbjct: 263 SPDDNYLVACGPDDCSELWLWN-VQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRG 321
Query: 365 QVKIWDL 371
Q DL
Sbjct: 322 QFYQCDL 328
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSN----VANFPGHVGPVTSISFSENGYYLATAAE 404
+F DG TG++++ V IW + ++ + GH V+ I++S + YL
Sbjct: 215 KFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGP 274
Query: 405 DSCVKLW 411
D C +LW
Sbjct: 275 DDCSELW 281
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLW----DLRKLKNFKTIQLEENYAIKELCFDQS 438
H V FS +G LAT ++D+ V +W D LK KT++ Y + + +
Sbjct: 207 HCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLE-GHAYGVSYIAWSPD 265
Query: 439 GTYLAIAGTD 448
YL G D
Sbjct: 266 DNYLVACGPD 275
>AY221751-1|AAO67709.1| 498|Homo sapiens myocardial ischemic
preconditioning upregulated protein 2 protein.
Length = 498
Score = 71.3 bits (167), Expect = 7e-12
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 17/283 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTE----QVVAILKGHTKKVTRVIYHPDEDTVITASPD-- 278
+D +KL TG D ++ D + +++ L+GH V+ + + PD++ ++ PD
Sbjct: 202 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDC 261
Query: 279 HTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKV 337
+ +WNV T + T + +SH+ +T ++ +P G ++ + D+ G LL
Sbjct: 262 SELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDL-DGNLL--- 317
Query: 338 SDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY 397
+ GV + DG + +++ ++ ++ ++ N P+ S + S+NG
Sbjct: 318 DSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTD-RNIVQEDHPIMSFTISKNGR 376
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCF-DQSGTYLAIAGTDVRVYLCR 455
V LWDL+ + Q + + + CF + ++A D +VY+
Sbjct: 377 LALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWH 436
Query: 456 QWQELKV--FNDHTASATGVRFGKN-AQYLASTSMDRTLKLYG 495
+ EL + HT + V + +AS S D T++++G
Sbjct: 437 KRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWG 479
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSL--- 307
IL H +V + D + T S D T+ +W V P + +L++ +G G+S
Sbjct: 187 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAW 246
Query: 308 HPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
P +Y+++ D + W ++ ++TG+L TK+S SLT+ ++PDG F TG +
Sbjct: 247 SPDDNYLVACGPDDCSELWLWN-VQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRG 305
Query: 365 QVKIWDL 371
Q DL
Sbjct: 306 QFYQCDL 312
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSN----VANFPGHVGPVTSISFSENGYYLATAAE 404
+F DG TG++++ V IW + ++ + GH V+ I++S + YL
Sbjct: 199 KFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGP 258
Query: 405 DSCVKLW 411
D C +LW
Sbjct: 259 DDCSELW 265
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLW----DLRKLKNFKTIQLEENYAIKELCFDQS 438
H V FS +G LAT ++D+ V +W D LK KT++ Y + + +
Sbjct: 191 HCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLE-GHAYGVSYIAWSPD 249
Query: 439 GTYLAIAGTD 448
YL G D
Sbjct: 250 DNYLVACGPD 259
>AY159316-1|AAO21313.1| 347|Homo sapiens lung cancer oncogene 7
protein.
Length = 347
Score = 71.3 bits (167), Expect = 7e-12
Identities = 52/192 (27%), Positives = 87/192 (45%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 103 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 162
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 163 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 222
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WDL E ++ G + ++ FS N Y+L
Sbjct: 223 GY-LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGG-DIINALCFSPNRYWLCA 280
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 281 ATGPS-IKIWDL 291
Score = 68.5 bits (160), Expect = 5e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 89 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 148
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 149 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 207
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 208 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LDGGDI 265
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 266 INALCFSPNRYWLCAATGPSIKIW 289
Score = 50.0 bits (114), Expect = 2e-05
Identities = 34/147 (23%), Positives = 65/147 (44%), Gaps = 7/147 (4%)
Query: 272 VITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSD 327
++ A+ H + L+ H+G VT ++ P D +LS S D+ W +
Sbjct: 18 ILVAAATHALAAAMTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTR 77
Query: 328 IRTGQLLTKVSDFSGVS--LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG 385
T + + + G S ++ DG +G+ + +++WDL + F GH
Sbjct: 78 DETNYGIPQRA-LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTK 136
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWD 412
V S++FS + + + + D +KLW+
Sbjct: 137 DVLSVAFSSDNRQIVSGSRDKTIKLWN 163
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 145 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 204
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 205 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 262
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 263 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 321
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 322 SADGQTLFAGYTDNLVRVWQV 342
>AK024669-1|BAB14955.1| 367|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21016 fis, clone CAE05735. ).
Length = 367
Score = 71.3 bits (167), Expect = 7e-12
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 17/283 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTE----QVVAILKGHTKKVTRVIYHPDEDTVITASPD-- 278
+D +KL TG D ++ D + +++ L+GH V+ + + PD++ ++ PD
Sbjct: 71 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDC 130
Query: 279 HTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKV 337
+ +WNV T + T + +SH+ +T ++ +P G ++ + D+ G LL
Sbjct: 131 SELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDL-DGNLL--- 186
Query: 338 SDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY 397
+ GV + DG + +++ ++ ++ ++ N P+ S + S+NG
Sbjct: 187 DSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTD-RNIVQEDHPIMSFTISKNGR 245
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCF-DQSGTYLAIAGTDVRVYLCR 455
V LWDL+ + Q + + + CF + ++A D +VY+
Sbjct: 246 LALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWH 305
Query: 456 QWQELKV--FNDHTASATGVRFGKN-AQYLASTSMDRTLKLYG 495
+ EL + HT + V + +AS S D T++++G
Sbjct: 306 KRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWG 348
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSL--- 307
IL H +V + D + T S D T+ +W V P + +L++ +G G+S
Sbjct: 56 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAW 115
Query: 308 HPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
P +Y+++ D + W ++ ++TG+L TK+S SLT+ ++PDG F TG +
Sbjct: 116 SPDDNYLVACGPDDCSELWLWN-VQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRG 174
Query: 365 QVKIWDL 371
Q DL
Sbjct: 175 QFYQCDL 181
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSN----VANFPGHVGPVTSISFSENGYYLATAAE 404
+F DG TG++++ V IW + ++ + GH V+ I++S + YL
Sbjct: 68 KFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGP 127
Query: 405 DSCVKLW 411
D C +LW
Sbjct: 128 DDCSELW 134
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLW----DLRKLKNFKTIQLEENYAIKELCFDQS 438
H V FS +G LAT ++D+ V +W D LK KT++ Y + + +
Sbjct: 60 HCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLE-GHAYGVSYIAWSPD 118
Query: 439 GTYLAIAGTD 448
YL G D
Sbjct: 119 DNYLVACGPD 128
>AB209887-1|BAD93124.1| 725|Homo sapiens WD repeat domain 26
variant protein.
Length = 725
Score = 71.3 bits (167), Expect = 7e-12
Identities = 62/283 (21%), Positives = 126/283 (44%), Gaps = 17/283 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTE----QVVAILKGHTKKVTRVIYHPDEDTVITASPD-- 278
+D +KL TG D ++ D + +++ L+GH V+ + + PD++ ++ PD
Sbjct: 429 NDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGPDDC 488
Query: 279 HTIRVWNVPTSQ-TTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKV 337
+ +WNV T + T + +SH+ +T ++ +P G ++ + D+ G LL
Sbjct: 489 SELWLWNVQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRGQFYQCDL-DGNLL--- 544
Query: 338 SDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY 397
+ GV + DG + +++ ++ ++ ++ N P+ S + S+NG
Sbjct: 545 DSWEGVRVQCLWCLSDGKTVLASDTHQRIRGYNFEDLTD-RNIVQEDHPIMSFTISKNGR 603
Query: 398 YLATAAEDSCVKLWDLRKLKNFKTIQ-LEENYAIKELCF-DQSGTYLAIAGTDVRVYLCR 455
V LWDL+ + Q + + + CF + ++A D +VY+
Sbjct: 604 LALLNVATQGVHLWDLQDRVLVRKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWH 663
Query: 456 QWQELKV--FNDHTASATGVRFGKN-AQYLASTSMDRTLKLYG 495
+ EL + HT + V + +AS S D T++++G
Sbjct: 664 KRSELPIAELTGHTRTVNCVSWNPQIPSMMASASDDGTVRIWG 706
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/127 (29%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTSQTTAILRSHDGPVTGLSL--- 307
IL H +V + D + T S D T+ +W V P + +L++ +G G+S
Sbjct: 414 ILTEHCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAW 473
Query: 308 HPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENS 364
P +Y+++ D + W ++ ++TG+L TK+S SLT+ ++PDG F TG +
Sbjct: 474 SPDDNYLVACGPDDCSELWLWN-VQTGELRTKMSQSHEDSLTSVAWNPDGKRFVTGGQRG 532
Query: 365 QVKIWDL 371
Q DL
Sbjct: 533 QFYQCDL 539
Score = 37.5 bits (83), Expect = 0.11
Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSN----VANFPGHVGPVTSISFSENGYYLATAAE 404
+F DG TG++++ V IW + ++ + GH V+ I++S + YL
Sbjct: 426 KFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDNYLVACGP 485
Query: 405 DSCVKLW 411
D C +LW
Sbjct: 486 DDCSELW 492
Score = 33.9 bits (74), Expect = 1.3
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLW----DLRKLKNFKTIQLEENYAIKELCFDQS 438
H V FS +G LAT ++D+ V +W D LK KT++ Y + + +
Sbjct: 418 HCNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLE-GHAYGVSYIAWSPD 476
Query: 439 GTYLAIAGTD 448
YL G D
Sbjct: 477 DNYLVACGPD 486
>BC012352-1|AAH12352.1| 366|Homo sapiens WDR31 protein protein.
Length = 366
Score = 70.9 bits (166), Expect = 9e-12
Identities = 51/194 (26%), Positives = 85/194 (43%), Gaps = 7/194 (3%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTS 289
++GG D+ +N T VV KGH ++T+V P +AS D + +W++ +S
Sbjct: 76 VSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSS 135
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
Q L H VTGL++ P + + S D D+ TGQ + + S V
Sbjct: 136 QPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCW 195
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE----D 405
+ I T +E+ +++WD + FP T S +G+ + + +
Sbjct: 196 VPREPYILQT-SEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGE 254
Query: 406 SC-VKLWDLRKLKN 418
C LWDLR+ +N
Sbjct: 255 GCEATLWDLRQTRN 268
Score = 62.1 bits (144), Expect = 4e-09
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 12/196 (6%)
Query: 228 SKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S+ + DR +++ + Q L GH VT + PD + T S D+T+ +W+V
Sbjct: 115 SQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDV 174
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLT 346
T Q+ VT L P Y+L TS D+ D R Q+ + T
Sbjct: 175 VTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQ-T 233
Query: 347 TAQFHPDG-----LIFGTGTENSQVKIWDLKEQSN-VANFPGHVGPVTSISFSENGYYL- 399
+ DG G G E + +WDL++ N + + GH V S F L
Sbjct: 234 YCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHFQTVASCVFLPRALALM 293
Query: 400 ---ATAAEDSCVKLWD 412
AT++ D VK+W+
Sbjct: 294 PLIATSSHDCKVKIWN 309
Score = 37.9 bits (84), Expect = 0.081
Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 15/190 (7%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ L ++P D S+L TG D +++ T Q V VT + + P E ++ S
Sbjct: 148 VTGLAVSP-DSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTS 206
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS-----DQHWAFSDIRTG 331
D T+R+W+ Q + + T + G +S S+ D+R
Sbjct: 207 EDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLR-- 264
Query: 332 QLLTKVSDFSGVSLTTAQ--FHPDGL----IFGTGTENSQVKIWDLKEQSNVANFP-GHV 384
Q ++ ++ G T A F P L + T + + +VKIW+ + +
Sbjct: 265 QTRNRICEYKGHFQTVASCVFLPRALALMPLIATSSHDCKVKIWNQDTGACLFTLSLDGS 324
Query: 385 GPVTSISFSE 394
GP+TS++ +
Sbjct: 325 GPLTSLAVGD 334
>BC005870-1|AAH05870.1| 315|Homo sapiens mitogen-activated protein
kinase organizer 1 protein.
Length = 315
Score = 70.9 bits (166), Expect = 9e-12
Identities = 51/191 (26%), Positives = 90/191 (47%), Gaps = 7/191 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D+S L +GG D+ +++ + QVV +GH KV V ++ + +++ S D +IR W+
Sbjct: 78 DNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWD 137
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDY-VLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
S+ +++ D G+S D+ +L+ S D D+R GQL SD+ G
Sbjct: 138 C-RSRRPEPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQLF---SDYVGSP 193
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSIS--FSENGYYLATA 402
+T F DG + +S +++ D + + GH + SE ++ +
Sbjct: 194 ITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSC 253
Query: 403 AEDSCVKLWDL 413
+ED V WDL
Sbjct: 254 SEDGKVFFWDL 264
Score = 57.6 bits (133), Expect = 9e-08
Identities = 51/197 (25%), Positives = 80/197 (40%), Gaps = 8/197 (4%)
Query: 300 GPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTA-QFHPDGLIFG 358
G V + + G+Y L+ SD+ + G LL S L A F L G
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSG 85
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
G + V +WD+ V F GH G V ++ F+E + + + DS ++ WD R +
Sbjct: 86 GG--DKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRP 143
Query: 419 FKTIQLEE-NYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTAS-ATGVRFG 476
L+E + + VR Y R Q +F+D+ S T F
Sbjct: 144 EPVQTLDEARDGVSSVKVSDHEILAGSVDGRVRRYDLRMGQ---LFSDYVGSPITCTCFS 200
Query: 477 KNAQYLASTSMDRTLKL 493
++ Q +S+D TL+L
Sbjct: 201 RDGQCTLVSSLDSTLRL 217
Score = 53.2 bits (122), Expect = 2e-06
Identities = 49/231 (21%), Positives = 92/231 (39%), Gaps = 10/231 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + LT G+D+ ++N ++ GH +V D ++ + D + +W+
Sbjct: 36 DGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWD 95
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSG 342
V + Q R H G V + + +LS S D W R + T G
Sbjct: 96 VASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDG 155
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATA 402
VS H G+ + +V+ +DL+ +++ G P+T FS +G +
Sbjct: 156 VSSVKVSDHE----ILAGSVDGRVRRYDLRMGQLFSDYVG--SPITCTCFSRDGQCTLVS 209
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENYAIK-ELCFDQSGTYLAIAGTDVRVY 452
+ DS ++L D + + +N K + C + T++ D +V+
Sbjct: 210 SLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVF 260
Score = 39.5 bits (88), Expect = 0.027
Identities = 26/112 (23%), Positives = 47/112 (41%), Gaps = 3/112 (2%)
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
G V ++ F+ +G Y T D +KLW+ + +T Y + + + L
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYS-GHGYEVLDAAGSFDNSSLCS 84
Query: 445 AGTDVRVYL--CRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
G D V L Q ++ F H V+F + A + S S+D +++ +
Sbjct: 85 GGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCW 136
Score = 33.1 bits (72), Expect = 2.3
Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRV-IYHPDEDT-VITASPDHTIRVWNVPT 288
L D + +KDT +++ KGH + ++ + DT V++ S D + W++
Sbjct: 207 LVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFWDLVE 266
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLST--SSDQHW 323
L G V L+ HPT +L+ S Q W
Sbjct: 267 GALALALPVGSGVVQSLAYHPTEPCLLTAMGGSVQCW 303
>AL449305-1|CAI10961.1| 367|Homo sapiens WD repeat domain 31
protein.
Length = 367
Score = 70.9 bits (166), Expect = 9e-12
Identities = 51/194 (26%), Positives = 85/194 (43%), Gaps = 7/194 (3%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTS 289
++GG D+ +N T VV KGH ++T+V P +AS D + +W++ +S
Sbjct: 77 VSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSS 136
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
Q L H VTGL++ P + + S D D+ TGQ + + S V
Sbjct: 137 QPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCW 196
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE----D 405
+ I T +E+ +++WD + FP T S +G+ + + +
Sbjct: 197 VPREPYILQT-SEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGE 255
Query: 406 SC-VKLWDLRKLKN 418
C LWDLR+ +N
Sbjct: 256 GCEATLWDLRQTRN 269
Score = 62.1 bits (144), Expect = 4e-09
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 12/196 (6%)
Query: 228 SKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S+ + DR +++ + Q L GH VT + PD + T S D+T+ +W+V
Sbjct: 116 SQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDV 175
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLT 346
T Q+ VT L P Y+L TS D+ D R Q+ + T
Sbjct: 176 VTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQ-T 234
Query: 347 TAQFHPDG-----LIFGTGTENSQVKIWDLKEQSN-VANFPGHVGPVTSISFSENGYYL- 399
+ DG G G E + +WDL++ N + + GH V S F L
Sbjct: 235 YCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHFQTVASCVFLPRALALM 294
Query: 400 ---ATAAEDSCVKLWD 412
AT++ D VK+W+
Sbjct: 295 PLIATSSHDCKVKIWN 310
Score = 37.9 bits (84), Expect = 0.081
Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 15/190 (7%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ L ++P D S+L TG D +++ T Q V VT + + P E ++ S
Sbjct: 149 VTGLAVSP-DSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTS 207
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS-----DQHWAFSDIRTG 331
D T+R+W+ Q + + T + G +S S+ D+R
Sbjct: 208 EDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLR-- 265
Query: 332 QLLTKVSDFSGVSLTTAQ--FHPDGL----IFGTGTENSQVKIWDLKEQSNVANFP-GHV 384
Q ++ ++ G T A F P L + T + + +VKIW+ + +
Sbjct: 266 QTRNRICEYKGHFQTVASCVFLPRALALMPLIATSSHDCKVKIWNQDTGACLFTLSLDGS 325
Query: 385 GPVTSISFSE 394
GP+TS++ +
Sbjct: 326 GPLTSLAVGD 335
>AL137066-1|CAH70096.1| 367|Homo sapiens WD repeat domain 31
protein.
Length = 367
Score = 70.9 bits (166), Expect = 9e-12
Identities = 51/194 (26%), Positives = 85/194 (43%), Gaps = 7/194 (3%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTS 289
++GG D+ +N T VV KGH ++T+V P +AS D + +W++ +S
Sbjct: 77 VSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSS 136
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
Q L H VTGL++ P + + S D D+ TGQ + + S V
Sbjct: 137 QPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCW 196
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE----D 405
+ I T +E+ +++WD + FP T S +G+ + + +
Sbjct: 197 VPREPYILQT-SEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGE 255
Query: 406 SC-VKLWDLRKLKN 418
C LWDLR+ +N
Sbjct: 256 GCEATLWDLRQTRN 269
Score = 62.1 bits (144), Expect = 4e-09
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 12/196 (6%)
Query: 228 SKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S+ + DR +++ + Q L GH VT + PD + T S D+T+ +W+V
Sbjct: 116 SQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDV 175
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLT 346
T Q+ VT L P Y+L TS D+ D R Q+ + T
Sbjct: 176 VTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQ-T 234
Query: 347 TAQFHPDG-----LIFGTGTENSQVKIWDLKEQSN-VANFPGHVGPVTSISFSENGYYL- 399
+ DG G G E + +WDL++ N + + GH V S F L
Sbjct: 235 YCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHFQTVASCVFLPRALALM 294
Query: 400 ---ATAAEDSCVKLWD 412
AT++ D VK+W+
Sbjct: 295 PLIATSSHDCKVKIWN 310
Score = 37.9 bits (84), Expect = 0.081
Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 15/190 (7%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ L ++P D S+L TG D +++ T Q V VT + + P E ++ S
Sbjct: 149 VTGLAVSP-DSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTS 207
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS-----DQHWAFSDIRTG 331
D T+R+W+ Q + + T + G +S S+ D+R
Sbjct: 208 EDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLR-- 265
Query: 332 QLLTKVSDFSGVSLTTAQ--FHPDGL----IFGTGTENSQVKIWDLKEQSNVANFP-GHV 384
Q ++ ++ G T A F P L + T + + +VKIW+ + +
Sbjct: 266 QTRNRICEYKGHFQTVASCVFLPRALALMPLIATSSHDCKVKIWNQDTGACLFTLSLDGS 325
Query: 385 GPVTSISFSE 394
GP+TS++ +
Sbjct: 326 GPLTSLAVGD 335
>AK093240-1|BAC04106.1| 367|Homo sapiens protein ( Homo sapiens
cDNA FLJ35921 fis, clone TESTI2010617, highly similar to
Mus musculus spermatid WD-repeat protein mRNA. ).
Length = 367
Score = 70.9 bits (166), Expect = 9e-12
Identities = 51/194 (26%), Positives = 85/194 (43%), Gaps = 7/194 (3%)
Query: 231 LTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV-PTS 289
++GG D+ +N T VV KGH ++T+V P +AS D + +W++ +S
Sbjct: 77 VSGGKDKTVVAYNWKTGNVVKRFKGHEHEITKVACIPKSSQFFSASRDRMVMMWDLHGSS 136
Query: 290 QTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
Q L H VTGL++ P + + S D D+ TGQ + + S V
Sbjct: 137 QPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCW 196
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE----D 405
+ I T +E+ +++WD + FP T S +G+ + + +
Sbjct: 197 VPREPYILQT-SEDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGE 255
Query: 406 SC-VKLWDLRKLKN 418
C LWDLR+ +N
Sbjct: 256 GCEATLWDLRQTRN 269
Score = 62.1 bits (144), Expect = 4e-09
Identities = 53/196 (27%), Positives = 81/196 (41%), Gaps = 12/196 (6%)
Query: 228 SKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNV 286
S+ + DR +++ + Q L GH VT + PD + T S D+T+ +W+V
Sbjct: 116 SQFFSASRDRMVMMWDLHGSSQPRQQLCGHAMVVTGLAVSPDSSQLCTGSRDNTLLLWDV 175
Query: 287 PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLT 346
T Q+ VT L P Y+L TS D+ D R Q+ + T
Sbjct: 176 VTGQSVERASVSRNVVTHLCWVPREPYILQTSEDKTLRLWDSRGLQVAHMFPAKQHIQ-T 234
Query: 347 TAQFHPDG-----LIFGTGTENSQVKIWDLKEQSN-VANFPGHVGPVTSISFSENGYYL- 399
+ DG G G E + +WDL++ N + + GH V S F L
Sbjct: 235 YCEVSVDGHKCISCSNGFGGEGCEATLWDLRQTRNRICEYKGHFQTVASCVFLPRALALM 294
Query: 400 ---ATAAEDSCVKLWD 412
AT++ D VK+W+
Sbjct: 295 PLIATSSHDCKVKIWN 310
Score = 37.9 bits (84), Expect = 0.081
Identities = 43/190 (22%), Positives = 78/190 (41%), Gaps = 15/190 (7%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+ L ++P D S+L TG D +++ T Q V VT + + P E ++ S
Sbjct: 149 VTGLAVSP-DSSQLCTGSRDNTLLLWDVVTGQSVERASVSRNVVTHLCWVPREPYILQTS 207
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSS-----DQHWAFSDIRTG 331
D T+R+W+ Q + + T + G +S S+ D+R
Sbjct: 208 EDKTLRLWDSRGLQVAHMFPAKQHIQTYCEVSVDGHKCISCSNGFGGEGCEATLWDLR-- 265
Query: 332 QLLTKVSDFSGVSLTTAQ--FHPDGL----IFGTGTENSQVKIWDLKEQSNVANFP-GHV 384
Q ++ ++ G T A F P L + T + + +VKIW+ + +
Sbjct: 266 QTRNRICEYKGHFQTVASCVFLPRALALMPLIATSSHDCKVKIWNQDTGACLFTLSLDGS 325
Query: 385 GPVTSISFSE 394
GP+TS++ +
Sbjct: 326 GPLTSLAVGD 335
>BT020045-1|AAV38848.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 70.1 bits (164), Expect = 2e-11
Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
D + LLTGG D+ +++ + E + GHT + + ++ ED I ++ D T+R+W
Sbjct: 111 DSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWC-SEDKQILSADDKTVRLW 169
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG-V 343
+ T L + + V+ + P G+ ++ T + AF + L + F
Sbjct: 170 DHATMTEVKSL-NFNMSVSSMEYIPEGEILVITYG-RSIAF---HSAVSLDPIKSFEAPA 224
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++ +A HP+ G E+ ++ +D + ++ GH GP+ + FS +G A+ +
Sbjct: 225 TINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGS 284
Query: 404 EDSCVKLW 411
ED ++LW
Sbjct: 285 EDGTLRLW 292
Score = 45.6 bits (103), Expect = 4e-04
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 377 VANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFD 436
+ F GH G V + +++ ATAA D K+WD + + + L + +K + F
Sbjct: 52 IGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWD--AVSGDELMTLAHKHIVKTVDFT 109
Query: 437 QSGTYLAIAGTD--VRVY-LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
Q YL G D +R+Y L + E K + HT+ + + + S D+T++L
Sbjct: 110 QDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSAD-DKTVRL 168
Query: 494 Y 494
+
Sbjct: 169 W 169
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/288 (20%), Positives = 104/288 (36%), Gaps = 11/288 (3%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H+ V + I P + L++ D + DT + GH V + D
Sbjct: 13 HTRPVVDLAFSGITPYGYF-LISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
TA+ D T +VW+ + L +H V + +Y+L+ D+ D+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 330 TGQLLTK-VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVT 388
+ K +S + D I ++ V++WD + V + ++ V+
Sbjct: 131 KPEAEPKEISGHTSGIKKALWCSEDKQILSA--DDKTVRLWDHATMTEVKSLNFNMS-VS 187
Query: 389 SISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
S+ + G L S + L K+ E I +L G D
Sbjct: 188 SMEYIPEGEILVITYGRS-IAFHSAVSLDPIKSF--EAPATINSASLHPEKEFLVAGGED 244
Query: 449 VRVYLC--RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++Y +EL+ + H VRF + + AS S D TL+L+
Sbjct: 245 FKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLW 292
Score = 36.3 bits (80), Expect = 0.25
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 199 AFLTLASHPGLHSASVPGIL-SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHT 257
AF + S + S P + S ++P + L+ GG D ++ ++ + + KGH
Sbjct: 207 AFHSAVSLDPIKSFEAPATINSASLHP-EKEFLVAGGEDFKLYKYDYNSGEELESYKGHF 265
Query: 258 KKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQT 291
+ V + PD + + S D T+R+W +T
Sbjct: 266 GPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKT 299
>BT020044-1|AAV38847.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 70.1 bits (164), Expect = 2e-11
Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
D + LLTGG D+ +++ + E + GHT + + ++ ED I ++ D T+R+W
Sbjct: 111 DSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWC-SEDKQILSADDKTVRLW 169
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG-V 343
+ T L + + V+ + P G+ ++ T + AF + L + F
Sbjct: 170 DHATMTEVKSL-NFNMSVSSMEYIPEGEILVITYG-RSIAF---HSAVSLDPIKSFEAPA 224
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++ +A HP+ G E+ ++ +D + ++ GH GP+ + FS +G A+ +
Sbjct: 225 TINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGS 284
Query: 404 EDSCVKLW 411
ED ++LW
Sbjct: 285 EDGTLRLW 292
Score = 45.6 bits (103), Expect = 4e-04
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 377 VANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFD 436
+ F GH G V + +++ ATAA D K+WD + + + L + +K + F
Sbjct: 52 IGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWD--AVSGDELMTLAHKHIVKTVDFT 109
Query: 437 QSGTYLAIAGTD--VRVY-LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
Q YL G D +R+Y L + E K + HT+ + + + S D+T++L
Sbjct: 110 QDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSAD-DKTVRL 168
Query: 494 Y 494
+
Sbjct: 169 W 169
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/288 (20%), Positives = 104/288 (36%), Gaps = 11/288 (3%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H+ V + I P + L++ D + DT + GH V + D
Sbjct: 13 HTRPVVDLAFSGITPYGYF-LISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
TA+ D T +VW+ + L +H V + +Y+L+ D+ D+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 330 TGQLLTK-VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVT 388
+ K +S + D I ++ V++WD + V + ++ V+
Sbjct: 131 KPEAEPKEISGHTSGIKKALWCSEDKQILSA--DDKTVRLWDHATMTEVKSLNFNMS-VS 187
Query: 389 SISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
S+ + G L S + L K+ E I +L G D
Sbjct: 188 SMEYIPEGEILVITYGRS-IAFHSAVSLDPIKSF--EAPATINSASLHPEKEFLVAGGED 244
Query: 449 VRVYLC--RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++Y +EL+ + H VRF + + AS S D TL+L+
Sbjct: 245 FKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLW 292
Score = 36.3 bits (80), Expect = 0.25
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 199 AFLTLASHPGLHSASVPGIL-SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHT 257
AF + S + S P + S ++P + L+ GG D ++ ++ + + KGH
Sbjct: 207 AFHSAVSLDPIKSFEAPATINSASLHP-EKEFLVAGGEDFKLYKYDYNSGEELESYKGHF 265
Query: 258 KKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQT 291
+ V + PD + + S D T+R+W +T
Sbjct: 266 GPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKT 299
>BC062306-1|AAH62306.1| 350|Homo sapiens serine/threonine kinase
receptor associated protein protein.
Length = 350
Score = 70.1 bits (164), Expect = 2e-11
Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
D + LLTGG D+ +++ + E + GHT + + ++ ED I ++ D T+R+W
Sbjct: 111 DSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWC-SEDKQILSADDKTVRLW 169
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG-V 343
+ T L + + V+ + P G+ ++ T + AF + L + F
Sbjct: 170 DHATMTEVKSL-NFNMSVSSMEYIPEGEILVITYG-RSIAF---HSAVSLDPIKSFEAPA 224
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++ +A HP+ G E+ ++ +D + ++ GH GP+ + FS +G A+ +
Sbjct: 225 TINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGS 284
Query: 404 EDSCVKLW 411
ED ++LW
Sbjct: 285 EDGTLRLW 292
Score = 45.6 bits (103), Expect = 4e-04
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 377 VANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFD 436
+ F GH G V + +++ ATAA D K+WD + + + L + +K + F
Sbjct: 52 IGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWD--AVSGDELMTLAHKHIVKTVDFT 109
Query: 437 QSGTYLAIAGTD--VRVY-LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
Q YL G D +R+Y L + E K + HT+ + + + S D+T++L
Sbjct: 110 QDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSAD-DKTVRL 168
Query: 494 Y 494
+
Sbjct: 169 W 169
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/288 (20%), Positives = 104/288 (36%), Gaps = 11/288 (3%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H+ V + I P + L++ D + DT + GH V + D
Sbjct: 13 HTRPVVDLAFSGITPYGYF-LISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
TA+ D T +VW+ + L +H V + +Y+L+ D+ D+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 330 TGQLLTK-VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVT 388
+ K +S + D I ++ V++WD + V + ++ V+
Sbjct: 131 KPEAEPKEISGHTSGIKKALWCSEDKQILSA--DDKTVRLWDHATMTEVKSLNFNMS-VS 187
Query: 389 SISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
S+ + G L S + L K+ E I +L G D
Sbjct: 188 SMEYIPEGEILVITYGRS-IAFHSAVSLDPIKSF--EAPATINSASLHPEKEFLVAGGED 244
Query: 449 VRVYLC--RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++Y +EL+ + H VRF + + AS S D TL+L+
Sbjct: 245 FKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLW 292
Score = 36.3 bits (80), Expect = 0.25
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 199 AFLTLASHPGLHSASVPGIL-SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHT 257
AF + S + S P + S ++P + L+ GG D ++ ++ + + KGH
Sbjct: 207 AFHSAVSLDPIKSFEAPATINSASLHP-EKEFLVAGGEDFKLYKYDYNSGEELESYKGHF 265
Query: 258 KKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQT 291
+ V + PD + + S D T+R+W +T
Sbjct: 266 GPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKT 299
>BC021905-1|AAH21905.1| 896|Homo sapiens Unknown (protein for
IMAGE:4341693) protein.
Length = 896
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/210 (22%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH +++ + + + + S D IRVW + T
Sbjct: 197 RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRT 256
Query: 289 SQTTAILRSHDGPVTGLSLHP--TGD--YVLSTSSDQHWAF--SDIRTGQLLTKVSDFS- 341
A+L+ H +T L P +G Y+ ST +D F D T ++ + + F+
Sbjct: 257 CAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTE 316
Query: 342 ----GVSLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ + ++ H V SI FS
Sbjct: 317 RPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNT 376
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
+ + D ++W ++ + +K+I L+
Sbjct: 377 SNRFVSGSRDGTARIWQFKR-REWKSILLD 405
Score = 47.6 bits (108), Expect = 1e-04
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G + T ++D VK+W + T++ I ++ + T
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLR-GHAAEISDMAVNYENTM 239
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK----NAQYLASTSMDRTL 491
+A D +RV+ R L V H+AS T ++F + +YL+ST D T+
Sbjct: 240 IAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTI 295
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 13/169 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS-QVKI 368
+ S D+ +RT L + S S+T+ QF P + TG + + +
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHS-ASITSLQFSPLCSGSKRYLSSTGADGTICFWL 299
Query: 369 WD---LKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLW 411
WD LK A F P + SFS G +LAT + D ++++
Sbjct: 300 WDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Score = 43.2 bits (97), Expect = 0.002
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-ST 317
KVT V + ++TVITA + T++VWN T Q +L H+ V L HP VL S
Sbjct: 426 KVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSA 485
Query: 318 SSDQHWAFSDIRTG 331
D + D+ G
Sbjct: 486 GHDGNVIVWDLARG 499
Score = 36.7 bits (81), Expect = 0.19
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 185 SVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGS 244
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ--SGT--YLAIAGTD 448
D +++W LR +Q + +I L F SG+ YL+ G D
Sbjct: 245 CDKMIRVWCLRTCAPLAVLQ-GHSASITSLQFSPLCSGSKRYLSSTGAD 292
Score = 35.9 bits (79), Expect = 0.33
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ +L GH +V + HP D + +A D + VW++
Sbjct: 439 VITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLAR 498
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
S I G V P G + T S H + K++D
Sbjct: 499 GVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIAD 554
>BC000162-1|AAH00162.1| 350|Homo sapiens serine/threonine kinase
receptor associated protein protein.
Length = 350
Score = 70.1 bits (164), Expect = 2e-11
Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
D + LLTGG D+ +++ + E + GHT + + ++ ED I ++ D T+R+W
Sbjct: 111 DSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWC-SEDKQILSADDKTVRLW 169
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG-V 343
+ T L + + V+ + P G+ ++ T + AF + L + F
Sbjct: 170 DHATMTEVKSL-NFNMSVSSMEYIPEGEILVITYG-RSIAF---HSAVSLDPIKSFEAPA 224
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++ +A HP+ G E+ ++ +D + ++ GH GP+ + FS +G A+ +
Sbjct: 225 TINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGS 284
Query: 404 EDSCVKLW 411
ED ++LW
Sbjct: 285 EDGTLRLW 292
Score = 45.6 bits (103), Expect = 4e-04
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 377 VANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFD 436
+ F GH G V + +++ ATAA D K+WD + + + L + +K + F
Sbjct: 52 IGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWD--AVSGDELMTLAHKHIVKTVDFT 109
Query: 437 QSGTYLAIAGTD--VRVY-LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
Q YL G D +R+Y L + E K + HT+ + + + S D+T++L
Sbjct: 110 QDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSAD-DKTVRL 168
Query: 494 Y 494
+
Sbjct: 169 W 169
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/288 (20%), Positives = 104/288 (36%), Gaps = 11/288 (3%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H+ V + I P + L++ D + DT + GH V + D
Sbjct: 13 HTRPVVDLAFSGITPYGYF-LISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
TA+ D T +VW+ + L +H V + +Y+L+ D+ D+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 330 TGQLLTK-VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVT 388
+ K +S + D I ++ V++WD + V + ++ V+
Sbjct: 131 KPEAEPKEISGHTSGIKKALWCSEDKQILSA--DDKTVRLWDHATMTEVKSLNFNMS-VS 187
Query: 389 SISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
S+ + G L S + L K+ E I +L G D
Sbjct: 188 SMEYIPEGEILVITYGRS-IAFHSAVSLDPIKSF--EAPATINSASLHPEKEFLVAGGED 244
Query: 449 VRVYLC--RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++Y +EL+ + H VRF + + AS S D TL+L+
Sbjct: 245 FKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLW 292
Score = 36.3 bits (80), Expect = 0.25
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 199 AFLTLASHPGLHSASVPGIL-SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHT 257
AF + S + S P + S ++P + L+ GG D ++ ++ + + KGH
Sbjct: 207 AFHSAVSLDPIKSFEAPATINSASLHP-EKEFLVAGGEDFKLYKYDYNSGEELESYKGHF 265
Query: 258 KKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQT 291
+ V + PD + + S D T+R+W +T
Sbjct: 266 GPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKT 299
>AY049776-1|AAL15433.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 70.1 bits (164), Expect = 2e-11
Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
D + LLTGG D+ +++ + E + GHT + + ++ ED I ++ D T+R+W
Sbjct: 111 DSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWC-SEDKQILSADDKTVRLW 169
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG-V 343
+ T L + + V+ + P G+ ++ T + AF + L + F
Sbjct: 170 DHATMTEVKSL-NFNMSVSSMEYIPEGEILVITYG-RSIAF---HSAVSLDPIKSFEAPA 224
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++ +A HP+ G E+ ++ +D + ++ GH GP+ + FS +G A+ +
Sbjct: 225 TINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGS 284
Query: 404 EDSCVKLW 411
ED ++LW
Sbjct: 285 EDGTLRLW 292
Score = 45.6 bits (103), Expect = 4e-04
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 377 VANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFD 436
+ F GH G V + +++ ATAA D K+WD + + + L + +K + F
Sbjct: 52 IGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWD--AVSGDELMTLAHKHIVKTVDFT 109
Query: 437 QSGTYLAIAGTD--VRVY-LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
Q YL G D +R+Y L + E K + HT+ + + + S D+T++L
Sbjct: 110 QDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSAD-DKTVRL 168
Query: 494 Y 494
+
Sbjct: 169 W 169
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/288 (20%), Positives = 104/288 (36%), Gaps = 11/288 (3%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H+ V + I P + L++ D + DT + GH V + D
Sbjct: 13 HTRPVVDLAFSGITPYGYF-LISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
TA+ D T +VW+ + L +H V + +Y+L+ D+ D+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 330 TGQLLTK-VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVT 388
+ K +S + D I ++ V++WD + V + ++ V+
Sbjct: 131 KPEAEPKEISGHTSGIKKALWCSEDKQILSA--DDKTVRLWDHATMTEVKSLNFNMS-VS 187
Query: 389 SISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
S+ + G L S + L K+ E I +L G D
Sbjct: 188 SMEYIPEGEILVITYGRS-IAFHSAVSLDPIKSF--EAPATINSASLHPEKEFLVAGGED 244
Query: 449 VRVYLC--RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++Y +EL+ + H VRF + + AS S D TL+L+
Sbjct: 245 FKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLW 292
Score = 36.3 bits (80), Expect = 0.25
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 199 AFLTLASHPGLHSASVPGIL-SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHT 257
AF + S + S P + S ++P + L+ GG D ++ ++ + + KGH
Sbjct: 207 AFHSAVSLDPIKSFEAPATINSASLHP-EKEFLVAGGEDFKLYKYDYNSGEELESYKGHF 265
Query: 258 KKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQT 291
+ V + PD + + S D T+R+W +T
Sbjct: 266 GPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKT 299
>AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( Human DNA
sequence from clone RP11-173D14 on chromosome 6. ).
Length = 1821
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/210 (22%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH +++ + + + + S D IRVW + T
Sbjct: 197 RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRT 256
Query: 289 SQTTAILRSHDGPVTGLSLHP--TGD--YVLSTSSDQHWAF--SDIRTGQLLTKVSDFS- 341
A+L+ H +T L P +G Y+ ST +D F D T ++ + + F+
Sbjct: 257 CAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTE 316
Query: 342 ----GVSLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ + ++ H V SI FS
Sbjct: 317 RPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNT 376
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
+ + D ++W ++ + +K+I L+
Sbjct: 377 SNRFVSGSRDGTARIWQFKR-REWKSILLD 405
Score = 47.6 bits (108), Expect = 1e-04
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G + T ++D VK+W + T++ I ++ + T
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLR-GHAAEISDMAVNYENTM 239
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK----NAQYLASTSMDRTL 491
+A D +RV+ R L V H+AS T ++F + +YL+ST D T+
Sbjct: 240 IAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTI 295
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 13/169 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS-QVKI 368
+ S D+ +RT L + S S+T+ QF P + TG + + +
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHS-ASITSLQFSPLCSGSKRYLSSTGADGTICFWL 299
Query: 369 WD---LKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLW 411
WD LK A F P + SFS G +LAT + D ++++
Sbjct: 300 WDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Score = 43.2 bits (97), Expect = 0.002
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-ST 317
KVT V + ++TVITA + T++VWN T Q +L H+ V L HP VL S
Sbjct: 426 KVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSA 485
Query: 318 SSDQHWAFSDIRTG 331
D + D+ G
Sbjct: 486 GHDGNVIVWDLARG 499
Score = 36.7 bits (81), Expect = 0.19
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 185 SVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGS 244
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ--SGT--YLAIAGTD 448
D +++W LR +Q + +I L F SG+ YL+ G D
Sbjct: 245 CDKMIRVWCLRTCAPLAVLQ-GHSASITSLQFSPLCSGSKRYLSSTGAD 292
Score = 35.9 bits (79), Expect = 0.33
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ +L GH +V + HP D + +A D + VW++
Sbjct: 439 VITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLAR 498
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
S I G V P G + T S H + K++D
Sbjct: 499 GVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIAD 554
>AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA
sequence from clone RP11-477E3 on chromosome 6. ).
Length = 1821
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/210 (22%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH +++ + + + + S D IRVW + T
Sbjct: 197 RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRT 256
Query: 289 SQTTAILRSHDGPVTGLSLHP--TGD--YVLSTSSDQHWAF--SDIRTGQLLTKVSDFS- 341
A+L+ H +T L P +G Y+ ST +D F D T ++ + + F+
Sbjct: 257 CAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTE 316
Query: 342 ----GVSLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ + ++ H V SI FS
Sbjct: 317 RPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNT 376
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
+ + D ++W ++ + +K+I L+
Sbjct: 377 SNRFVSGSRDGTARIWQFKR-REWKSILLD 405
Score = 47.6 bits (108), Expect = 1e-04
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G + T ++D VK+W + T++ I ++ + T
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLR-GHAAEISDMAVNYENTM 239
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK----NAQYLASTSMDRTL 491
+A D +RV+ R L V H+AS T ++F + +YL+ST D T+
Sbjct: 240 IAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTI 295
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 13/169 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS-QVKI 368
+ S D+ +RT L + S S+T+ QF P + TG + + +
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHS-ASITSLQFSPLCSGSKRYLSSTGADGTICFWL 299
Query: 369 WD---LKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLW 411
WD LK A F P + SFS G +LAT + D ++++
Sbjct: 300 WDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Score = 43.2 bits (97), Expect = 0.002
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-ST 317
KVT V + ++TVITA + T++VWN T Q +L H+ V L HP VL S
Sbjct: 426 KVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSA 485
Query: 318 SSDQHWAFSDIRTG 331
D + D+ G
Sbjct: 486 GHDGNVIVWDLARG 499
Score = 36.7 bits (81), Expect = 0.19
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 185 SVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGS 244
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ--SGT--YLAIAGTD 448
D +++W LR +Q + +I L F SG+ YL+ G D
Sbjct: 245 CDKMIRVWCLRTCAPLAVLQ-GHSASITSLQFSPLCSGSKRYLSSTGAD 292
Score = 35.9 bits (79), Expect = 0.33
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ +L GH +V + HP D + +A D + VW++
Sbjct: 439 VITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLAR 498
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
S I G V P G + T S H + K++D
Sbjct: 499 GVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIAD 554
>AK057039-1|BAB71353.1| 912|Homo sapiens protein ( Homo sapiens
cDNA FLJ32477 fis, clone SKNMC2000698, highly similar to
Mus musculus ndrp mRNA for neuronal differentiaion
related ).
Length = 912
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/210 (22%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH +++ + + + + S D IRVW + T
Sbjct: 197 RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRT 256
Query: 289 SQTTAILRSHDGPVTGLSLHP--TGD--YVLSTSSDQHWAF--SDIRTGQLLTKVSDFS- 341
A+L+ H +T L P +G Y+ ST +D F D T ++ + + F+
Sbjct: 257 CAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTE 316
Query: 342 ----GVSLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ + ++ H V SI FS
Sbjct: 317 RPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNT 376
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
+ + D ++W ++ + +K+I L+
Sbjct: 377 SNRFVSGSRDGTARIWQFKR-REWKSILLD 405
Score = 47.6 bits (108), Expect = 1e-04
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G + T ++D VK+W + T++ I ++ + T
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLR-GHAAEISDMAVNYENTM 239
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK----NAQYLASTSMDRTL 491
+A D +RV+ R L V H+AS T ++F + +YL+ST D T+
Sbjct: 240 IAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTI 295
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 13/169 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS-QVKI 368
+ S D+ +RT L + S S+T+ QF P + TG + + +
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHS-ASITSLQFSPLCSGSKRYLSSTGADGTICFWL 299
Query: 369 WD---LKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLW 411
WD LK A F P + SFS G +LAT + D ++++
Sbjct: 300 WDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Score = 43.2 bits (97), Expect = 0.002
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-ST 317
KVT V + ++TVITA + T++VWN T Q +L H+ V L HP VL S
Sbjct: 426 KVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSA 485
Query: 318 SSDQHWAFSDIRTG 331
D + D+ G
Sbjct: 486 GHDGNVIVWDLARG 499
Score = 36.7 bits (81), Expect = 0.19
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 185 SVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGS 244
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ--SGT--YLAIAGTD 448
D +++W LR +Q + +I L F SG+ YL+ G D
Sbjct: 245 CDKMIRVWCLRTCAPLAVLQ-GHSASITSLQFSPLCSGSKRYLSSTGAD 292
Score = 35.9 bits (79), Expect = 0.33
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ +L GH +V + HP D + +A D + VW++
Sbjct: 439 VITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLAR 498
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
S I G V P G + T S H + K++D
Sbjct: 499 GVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIAD 554
>AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11
protein protein.
Length = 1821
Score = 70.1 bits (164), Expect = 2e-11
Identities = 47/210 (22%), Positives = 97/210 (46%), Gaps = 14/210 (6%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
++ TG +D ++ D +++A L+GH +++ + + + + S D IRVW + T
Sbjct: 197 RIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRT 256
Query: 289 SQTTAILRSHDGPVTGLSLHP--TGD--YVLSTSSDQHWAF--SDIRTGQLLTKVSDFS- 341
A+L+ H +T L P +G Y+ ST +D F D T ++ + + F+
Sbjct: 257 CAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTE 316
Query: 342 ----GVSLTTAQFHPDGLIFGTGTENSQVKIW--DLKEQSNVANFPGHVGPVTSISFSEN 395
GV + + F G+ TG+ + ++++ + ++ H V SI FS
Sbjct: 317 RPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNT 376
Query: 396 GYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
+ + D ++W ++ + +K+I L+
Sbjct: 377 SNRFVSGSRDGTARIWQFKR-REWKSILLD 405
Score = 47.6 bits (108), Expect = 1e-04
Identities = 31/116 (26%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 382 GHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTY 441
GH+ V ++F G + T ++D VK+W + T++ I ++ + T
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLR-GHAAEISDMAVNYENTM 239
Query: 442 LAIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGK----NAQYLASTSMDRTL 491
+A D +RV+ R L V H+AS T ++F + +YL+ST D T+
Sbjct: 240 IAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTI 295
Score = 44.0 bits (99), Expect = 0.001
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 13/169 (7%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYV 314
GH V V + + T S D +++W + A LR H ++ ++++ +
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240
Query: 315 LSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHP-----DGLIFGTGTENS-QVKI 368
+ S D+ +RT L + S S+T+ QF P + TG + + +
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHS-ASITSLQFSPLCSGSKRYLSSTGADGTICFWL 299
Query: 369 WD---LKEQSNVANFPGHVGPVTSI---SFSENGYYLATAAEDSCVKLW 411
WD LK A F P + SFS G +LAT + D ++++
Sbjct: 300 WDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVY 348
Score = 43.2 bits (97), Expect = 0.002
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
Query: 259 KVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-ST 317
KVT V + ++TVITA + T++VWN T Q +L H+ V L HP VL S
Sbjct: 426 KVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSA 485
Query: 318 SSDQHWAFSDIRTG 331
D + D+ G
Sbjct: 486 GHDGNVIVWDLARG 499
Score = 36.7 bits (81), Expect = 0.19
Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
S+ F G TG+++ VKIW + +A GH ++ ++ + +A +
Sbjct: 185 SVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGS 244
Query: 404 EDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQ--SGT--YLAIAGTD 448
D +++W LR +Q + +I L F SG+ YL+ G D
Sbjct: 245 CDKMIRVWCLRTCAPLAVLQ-GHSASITSLQFSPLCSGSKRYLSSTGAD 292
Score = 35.9 bits (79), Expect = 0.33
Identities = 28/116 (24%), Positives = 46/116 (39%), Gaps = 6/116 (5%)
Query: 230 LLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP-DEDTVITASPDHTIRVWNVP- 287
++T N+ V+N T Q++ +L GH +V + HP D + +A D + VW++
Sbjct: 439 VITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLAR 498
Query: 288 ----TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSD 339
S I G V P G + T S H + K++D
Sbjct: 499 GVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIAD 554
>AJ010025-1|CAB38041.1| 350|Homo sapiens unr-interacting protein
protein.
Length = 350
Score = 70.1 bits (164), Expect = 2e-11
Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
D + LLTGG D+ +++ + E + GHT + + ++ ED I ++ D T+R+W
Sbjct: 111 DSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWC-SEDKQILSADDKTVRLW 169
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG-V 343
+ T L + + V+ + P G+ ++ T + AF + L + F
Sbjct: 170 DHATMTEVKSL-NFNMSVSSMEYIPEGEILVITYG-RSIAF---HSAVSLDPIKSFEAPA 224
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++ +A HP+ G E+ ++ +D + ++ GH GP+ + FS +G A+ +
Sbjct: 225 TINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGS 284
Query: 404 EDSCVKLW 411
ED ++LW
Sbjct: 285 EDGTLRLW 292
Score = 45.6 bits (103), Expect = 4e-04
Identities = 32/121 (26%), Positives = 56/121 (46%), Gaps = 6/121 (4%)
Query: 377 VANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFD 436
+ F GH G V + +++ ATAA D K+WD + + + L + +K + F
Sbjct: 52 IGTFLGHKGAVWGATLNKDATKAATAAADFTAKVWD--AVSGDELMTLAHKHIVKTVDFT 109
Query: 437 QSGTYLAIAGTD--VRVY-LCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
Q YL G D +R+Y L + E K + HT+ + + + S D+T++L
Sbjct: 110 QDSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWCSEDKQILSAD-DKTVRL 168
Query: 494 Y 494
+
Sbjct: 169 W 169
Score = 44.4 bits (100), Expect = 0.001
Identities = 59/288 (20%), Positives = 104/288 (36%), Gaps = 11/288 (3%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H+ V + I P + L++ D + DT + GH V + D
Sbjct: 13 HTRPVVDLAFSGITPYGYF-LISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
TA+ D T +VW+ + L +H V + +Y+L+ D+ D+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 330 TGQLLTK-VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVT 388
+ K +S + D I ++ V++WD + V + ++ V+
Sbjct: 131 KPEAEPKEISGHTSGIKKALWCSEDKQILSA--DDKTVRLWDHATMTEVKSLNFNMS-VS 187
Query: 389 SISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
S+ + G L S + L K+ E I +L G D
Sbjct: 188 SMEYIPEGEILVITYGRS-IAFHSAVSLDPIKSF--EAPATINSASLHPEKEFLVAGGED 244
Query: 449 VRVYLC--RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++Y +EL+ + H VRF + + AS S D TL+L+
Sbjct: 245 FKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLW 292
Score = 36.3 bits (80), Expect = 0.25
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 199 AFLTLASHPGLHSASVPGIL-SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHT 257
AF + S + S P + S ++P + L+ GG D ++ ++ + + KGH
Sbjct: 207 AFHSAVSLDPIKSFEAPATINSASLHP-EKEFLVAGGEDFKLYKYDYNSGEELESYKGHF 265
Query: 258 KKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQT 291
+ V + PD + + S D T+R+W +T
Sbjct: 266 GPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKT 299
>AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein.
Length = 1336
Score = 70.1 bits (164), Expect = 2e-11
Identities = 52/208 (25%), Positives = 91/208 (43%), Gaps = 7/208 (3%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
+ A I +P+D+ K T +D +++ IL+GH V V +HP
Sbjct: 197 MFQAHKEAIREASFSPTDN-KFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPT 255
Query: 269 EDTVITASPD--HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
+ V++ S D I+ W+ T Q+ A L +H V + L+ G+++L+ S D
Sbjct: 256 KGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLF 315
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFP-GH 383
DIR + +V T +HP +GL F +G + + W + + V H
Sbjct: 316 DIRNLKEELQVFRGHKKEATAVAWHPVHEGL-FASGGSDGSLLFWHVGVEKEVGGMEMAH 374
Query: 384 VGPVTSISFSENGYYLATAAEDSCVKLW 411
G + S+++ G+ L + + D K W
Sbjct: 375 EGMIWSLAWHPLGHILCSGSNDHTSKFW 402
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/194 (24%), Positives = 86/194 (44%), Gaps = 10/194 (5%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
+L+TG + T++N T IL+ H V + + ++ ++TA ++ W
Sbjct: 133 RLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQ-SN 191
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSL 345
+ ++H + S PT + + S D + W F ++L G +
Sbjct: 192 MNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRG----HGADV 247
Query: 346 TTAQFHPDGLIFGTGTENSQ--VKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+HP + +G+++SQ +K WD K ++A H V + + NG +L TA+
Sbjct: 248 KCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTAS 307
Query: 404 EDSCVKLWDLRKLK 417
D KL+D+R LK
Sbjct: 308 RDHLCKLFDIRNLK 321
Score = 60.1 bits (139), Expect = 2e-08
Identities = 48/219 (21%), Positives = 93/219 (42%), Gaps = 14/219 (6%)
Query: 263 VIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH 322
V + P+ ++T + +WN T IL++HD PV ++ ++L+ +
Sbjct: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184
Query: 323 WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ + K+ ++ A F P F T +++ V+IWD G
Sbjct: 185 VKYWQSNMNNV--KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRG 242
Query: 383 HVGPVTSISFSENGYYLATAAEDS--CVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGT 440
H V + + + + ++DS +K WD + ++ T+ +N + E+ + +G
Sbjct: 243 HGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKN-TVMEVKLNLNGN 301
Query: 441 YLAIAGTDVRVYLCRQW------QELKVFNDHTASATGV 473
+L A D +LC+ + +EL+VF H AT V
Sbjct: 302 WLLTASRD---HLCKLFDIRNLKEELQVFRGHKKEATAV 337
Score = 58.8 bits (136), Expect = 4e-08
Identities = 46/204 (22%), Positives = 85/204 (41%), Gaps = 7/204 (3%)
Query: 250 VAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHP 309
V + + H + + + P ++ T S D T+R+W+ ILR H V + HP
Sbjct: 195 VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHP 254
Query: 310 TGDYVLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVK 367
T V+S S D Q F D +TGQ L + ++ + + +G T + + K
Sbjct: 255 TKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKN-TVMEVKLNLNGNWLLTASRDHLCK 313
Query: 368 IWDLKE-QSNVANFPGHVGPVTSISFS--ENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++D++ + + F GH T++++ G + A+ D + W + K +++
Sbjct: 314 LFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLF-ASGGSDGSLLFWHVGVEKEVGGMEM 372
Query: 425 EENYAIKELCFDQSGTYLAIAGTD 448
I L + G L D
Sbjct: 373 AHEGMIWSLAWHPLGHILCSGSND 396
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 10/144 (6%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T VK W +NV F H + SFS AT ++D V++WD +
Sbjct: 178 TADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHE 236
Query: 419 FKTIQLEENYAIKELCFDQSGTY-LAIAGTDVRVYLCRQW-----QELKVFNDHTASATG 472
+ ++ + C D T L ++G+ + W Q L + H +
Sbjct: 237 ERILR---GHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVME 293
Query: 473 VRFGKNAQYLASTSMDRTLKLYGI 496
V+ N +L + S D KL+ I
Sbjct: 294 VKLNLNGNWLLTASRDHLCKLFDI 317
>AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein.
Length = 1336
Score = 70.1 bits (164), Expect = 2e-11
Identities = 52/208 (25%), Positives = 91/208 (43%), Gaps = 7/208 (3%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
+ A I +P+D+ K T +D +++ IL+GH V V +HP
Sbjct: 197 MFQAHKEAIREASFSPTDN-KFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPT 255
Query: 269 EDTVITASPD--HTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS 326
+ V++ S D I+ W+ T Q+ A L +H V + L+ G+++L+ S D
Sbjct: 256 KGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLF 315
Query: 327 DIRTGQLLTKVSDFSGVSLTTAQFHP--DGLIFGTGTENSQVKIWDLKEQSNVANFP-GH 383
DIR + +V T +HP +GL F +G + + W + + V H
Sbjct: 316 DIRNLKEELQVFRGHKKEATAVAWHPVHEGL-FASGGSDGSLLFWHVGVEKEVGGMEMAH 374
Query: 384 VGPVTSISFSENGYYLATAAEDSCVKLW 411
G + S+++ G+ L + + D K W
Sbjct: 375 EGMIWSLAWHPLGHILCSGSNDHTSKFW 402
Score = 68.1 bits (159), Expect = 7e-11
Identities = 47/194 (24%), Positives = 86/194 (44%), Gaps = 10/194 (5%)
Query: 229 KLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
+L+TG + T++N T IL+ H V + + ++ ++TA ++ W
Sbjct: 133 RLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQ-SN 191
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSDIRTGQLLTKVSDFSGVSL 345
+ ++H + S PT + + S D + W F ++L G +
Sbjct: 192 MNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRG----HGADV 247
Query: 346 TTAQFHPDGLIFGTGTENSQ--VKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
+HP + +G+++SQ +K WD K ++A H V + + NG +L TA+
Sbjct: 248 KCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTAS 307
Query: 404 EDSCVKLWDLRKLK 417
D KL+D+R LK
Sbjct: 308 RDHLCKLFDIRNLK 321
Score = 60.1 bits (139), Expect = 2e-08
Identities = 48/219 (21%), Positives = 93/219 (42%), Gaps = 14/219 (6%)
Query: 263 VIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH 322
V + P+ ++T + +WN T IL++HD PV ++ ++L+ +
Sbjct: 125 VRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGY 184
Query: 323 WAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPG 382
+ + K+ ++ A F P F T +++ V+IWD G
Sbjct: 185 VKYWQSNMNNV--KMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRG 242
Query: 383 HVGPVTSISFSENGYYLATAAEDS--CVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGT 440
H V + + + + ++DS +K WD + ++ T+ +N + E+ + +G
Sbjct: 243 HGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKN-TVMEVKLNLNGN 301
Query: 441 YLAIAGTDVRVYLCRQW------QELKVFNDHTASATGV 473
+L A D +LC+ + +EL+VF H AT V
Sbjct: 302 WLLTASRD---HLCKLFDIRNLKEELQVFRGHKKEATAV 337
Score = 58.8 bits (136), Expect = 4e-08
Identities = 46/204 (22%), Positives = 85/204 (41%), Gaps = 7/204 (3%)
Query: 250 VAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHP 309
V + + H + + + P ++ T S D T+R+W+ ILR H V + HP
Sbjct: 195 VKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHP 254
Query: 310 TGDYVLSTSSD--QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVK 367
T V+S S D Q F D +TGQ L + ++ + + +G T + + K
Sbjct: 255 TKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKN-TVMEVKLNLNGNWLLTASRDHLCK 313
Query: 368 IWDLKE-QSNVANFPGHVGPVTSISFS--ENGYYLATAAEDSCVKLWDLRKLKNFKTIQL 424
++D++ + + F GH T++++ G + A+ D + W + K +++
Sbjct: 314 LFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLF-ASGGSDGSLLFWHVGVEKEVGGMEM 372
Query: 425 EENYAIKELCFDQSGTYLAIAGTD 448
I L + G L D
Sbjct: 373 AHEGMIWSLAWHPLGHILCSGSND 396
Score = 44.8 bits (101), Expect = 7e-04
Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 10/144 (6%)
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
T VK W +NV F H + SFS AT ++D V++WD +
Sbjct: 178 TADHGGYVKYWQ-SNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHE 236
Query: 419 FKTIQLEENYAIKELCFDQSGTY-LAIAGTDVRVYLCRQW-----QELKVFNDHTASATG 472
+ ++ + C D T L ++G+ + W Q L + H +
Sbjct: 237 ERILR---GHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVME 293
Query: 473 VRFGKNAQYLASTSMDRTLKLYGI 496
V+ N +L + S D KL+ I
Sbjct: 294 VKLNLNGNWLLTASRDHLCKLFDI 317
>AB024327-1|BAA75544.1| 350|Homo sapiens WD-40 repeat protein
protein.
Length = 350
Score = 70.1 bits (164), Expect = 2e-11
Identities = 46/188 (24%), Positives = 90/188 (47%), Gaps = 8/188 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
D + LLTGG D+ +++ + E + GHT + + ++ ED I ++ D T+R+W
Sbjct: 111 DSNYLLTGGQDKLLRIYDLNKPEAEPKEISGHTSGIKKALWC-SEDKQILSADDKTVRLW 169
Query: 285 NVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG-V 343
+ T L + + V+ + P G+ ++ T + AF + L + F
Sbjct: 170 DHATMTEVKSL-NFNMSVSSMEYIPEGEILVITYG-RSIAF---HSAVSLDPIKSFEAPA 224
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++ +A HP+ G E+ ++ +D + ++ GH GP+ + FS +G A+ +
Sbjct: 225 TINSASLHPEKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGS 284
Query: 404 EDSCVKLW 411
ED ++LW
Sbjct: 285 EDGTLRLW 292
Score = 47.2 bits (107), Expect = 1e-04
Identities = 60/288 (20%), Positives = 105/288 (36%), Gaps = 11/288 (3%)
Query: 210 HSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDE 269
H+ V + DI P + L++ D + DT + GH V + D
Sbjct: 13 HTRPVVDLAFSDITPYGYF-LISACKDGKPMLRQGDTGDWIGTFLGHKGAVWGATLNKDA 71
Query: 270 DTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
TA+ D T +VW+ + L +H V + +Y+L+ D+ D+
Sbjct: 72 TKAATAAADFTAKVWDAVSGDELMTL-AHKHIVKTVDFTQDSNYLLTGGQDKLLRIYDLN 130
Query: 330 TGQLLTK-VSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVT 388
+ K +S + D I ++ V++WD + V + ++ V+
Sbjct: 131 KPEAEPKEISGHTSGIKKALWCSEDKQILSA--DDKTVRLWDHATMTEVKSLNFNMS-VS 187
Query: 389 SISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD 448
S+ + G L S + L K+ E I +L G D
Sbjct: 188 SMEYIPEGEILVITYGRS-IAFHSAVSLDPIKSF--EAPATINSASLHPEKEFLVAGGED 244
Query: 449 VRVYLC--RQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
++Y +EL+ + H VRF + + AS S D TL+L+
Sbjct: 245 FKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLW 292
Score = 36.3 bits (80), Expect = 0.25
Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 199 AFLTLASHPGLHSASVPGIL-SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHT 257
AF + S + S P + S ++P + L+ GG D ++ ++ + + KGH
Sbjct: 207 AFHSAVSLDPIKSFEAPATINSASLHP-EKEFLVAGGEDFKLYKYDYNSGEELESYKGHF 265
Query: 258 KKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQT 291
+ V + PD + + S D T+R+W +T
Sbjct: 266 GPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKT 299
>AK222488-1|BAD96208.1| 317|Homo sapiens guanine nucleotide binding
protein (G protein), beta polypeptide 2-like 1 varia
protein.
Length = 317
Score = 69.7 bits (163), Expect = 2e-11
Identities = 51/192 (26%), Positives = 86/192 (44%), Gaps = 6/192 (3%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
SD L+G D +++ T GHTK V V + D +++ S D TI++W
Sbjct: 73 SDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW 132
Query: 285 N-VPTSQTTAILRSHDGPVTGLSLHP--TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
N + + T SH V+ + P + ++S D+ ++ +L T +
Sbjct: 133 NTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHT 192
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
G L T PDG + +G ++ Q +WD E ++ G + ++ FS N Y+L
Sbjct: 193 GY-LNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTLDGG-DIINALCFSPNRYWLCA 250
Query: 402 AAEDSCVKLWDL 413
A S +K+WDL
Sbjct: 251 ATGPS-IKIWDL 261
Score = 66.9 bits (156), Expect = 2e-10
Identities = 49/204 (24%), Positives = 90/204 (44%), Gaps = 7/204 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH+ V+ V+ D ++ S D T+R+W++ T TT H V ++
Sbjct: 59 LRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNR 118
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDG---LIFGTGTENSQVKIW 369
++S S D+ + T + ++ +F P+ +I G + VK+W
Sbjct: 119 QIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVW 177
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+L N GH G + +++ S +G A+ +D LWD + K+ T L+
Sbjct: 178 NLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYT--LDGGDI 235
Query: 430 IKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 236 INALCFSPNRYWLCAATGPSIKIW 259
Score = 48.0 bits (109), Expect = 8e-05
Identities = 32/124 (25%), Positives = 59/124 (47%), Gaps = 7/124 (5%)
Query: 295 LRSHDGPVTGLSLHPT-GDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSGVS--LTTA 348
L+ H+G VT ++ P D +LS S D+ W + T + + + G S ++
Sbjct: 11 LKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRA-LRGHSHFVSDV 69
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
DG +G+ + +++WDL + F GH V S++FS + + + + D +
Sbjct: 70 VISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTI 129
Query: 409 KLWD 412
KLW+
Sbjct: 130 KLWN 133
Score = 44.4 bits (100), Expect = 0.001
Identities = 42/201 (20%), Positives = 84/201 (41%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 115 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 174
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D G+ L +
Sbjct: 175 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTLD--G 232
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 233 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 291
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 292 SADGQTLFAGYTDNLVRVWQV 312
>AF127799-1|AAP97249.1| 305|Homo sapiens G protein beta
subunit-like protein protein.
Length = 305
Score = 69.7 bits (163), Expect = 2e-11
Identities = 53/230 (23%), Positives = 96/230 (41%), Gaps = 6/230 (2%)
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTA--ILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAF 325
+ +TV+T S D ++VW + L H V + + T S+S D H
Sbjct: 31 NSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRL 90
Query: 326 SDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVG 385
D+ G+ + + D V T F PD TGT +V I+ ++ +
Sbjct: 91 RDLENGKQIKSI-DAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGK 149
Query: 386 PVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIA 445
+ SI++S +G YLA+ A D + ++ + K T++ I+ L F L A
Sbjct: 150 FILSIAYSPDGKYLASGAIDGIINIFAIATGKLLHTLE-GHAMPIRSLTFSPDSQLLVTA 208
Query: 446 GTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKL 493
D +++Y + + H + V F + + S+S D+++K+
Sbjct: 209 SDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKV 258
Score = 63.3 bits (147), Expect = 2e-09
Identities = 40/187 (21%), Positives = 80/187 (42%), Gaps = 1/187 (0%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D L TG + +F ++ + L K + + Y PD + + + D I ++
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFA 176
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
+ T + L H P+ L+ P +++ S D + D++ L +S + L
Sbjct: 177 IATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVL 236
Query: 346 TTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAED 405
A F PD F + + + VK+ D+ ++ V F H V + ++ NG + + +D
Sbjct: 237 NVA-FCPDDTHFVSSSSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 406 SCVKLWD 412
+ ++D
Sbjct: 296 QEIHIYD 302
Score = 57.2 bits (132), Expect = 1e-07
Identities = 51/246 (20%), Positives = 103/246 (41%), Gaps = 8/246 (3%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHD-GPVTG--LSLHP 309
L+GH V V ++S D IR+ ++ + ++S D GPV L+ P
Sbjct: 60 LEGHQLGVVSVDISHTLPIAASSSLDAHIRLRDLENGKQ---IKSIDAGPVDAWTLAFSP 116
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
Y+ + + + +G+ + D G + + + PDG +G + + I+
Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSL-DTRGKFILSIAYSPDGKYLASGAIDGIINIF 175
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+ + GH P+ S++FS + L TA++D +K++D++ T+ ++
Sbjct: 176 AIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWV 235
Query: 430 IK-ELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMD 488
+ C D + + + V+V + F DH GV++ N + S D
Sbjct: 236 LNVAFCPDDTHFVSSSSDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDD 295
Query: 489 RTLKLY 494
+ + +Y
Sbjct: 296 QEIHIY 301
Score = 53.2 bits (122), Expect = 2e-06
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
ILS+ +P D L +G D +F T +++ L+GH + + + PD ++TAS
Sbjct: 151 ILSIAYSP-DGKYLASGAIDGIINIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTAS 209
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
D I++++V + L H V ++ P + +S+SSD+ D+ T
Sbjct: 210 DDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVRDVGT 263
Score = 48.0 bits (109), Expect = 8e-05
Identities = 27/105 (25%), Positives = 47/105 (44%), Gaps = 1/105 (0%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
I SL +P D L+T +D +++ + L GH V V + PD+ +++S
Sbjct: 193 IRSLTFSP-DSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSS 251
Query: 277 PDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQ 321
D +++V +V T H V G+ + G ++S DQ
Sbjct: 252 SDKSVKVRDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQ 296
>AK223195-1|BAD96915.1| 315|Homo sapiens mitogen-activated protein
kinase organizer 1 variant protein.
Length = 315
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/191 (26%), Positives = 90/191 (47%), Gaps = 7/191 (3%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D+S L +GG D+ +++ + QVV +GH KV V ++ + +++ S D +IR W+
Sbjct: 78 DNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWD 137
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDY-VLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
S+ +++ D G+S D+ +L+ S D D+R GQL SD+ G
Sbjct: 138 C-RSRRPEPVQTLDEARDGVSSVKVLDHEILAGSVDGRVRRYDLRMGQLF---SDYVGSP 193
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSIS--FSENGYYLATA 402
+T F DG + +S +++ D + + GH + SE ++ +
Sbjct: 194 ITCTCFSRDGQCTLVSSLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSC 253
Query: 403 AEDSCVKLWDL 413
+ED V WDL
Sbjct: 254 SEDGKVFFWDL 264
Score = 56.0 bits (129), Expect = 3e-07
Identities = 51/197 (25%), Positives = 80/197 (40%), Gaps = 8/197 (4%)
Query: 300 GPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTA-QFHPDGLIFG 358
G V + + G+Y L+ SD+ + G LL S L A F L G
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSG 85
Query: 359 TGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKN 418
G + V +WD+ V F GH G V ++ F+E + + + DS ++ WD R +
Sbjct: 86 GG--DKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRP 143
Query: 419 FKTIQLEE-NYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTAS-ATGVRFG 476
L+E + + VR Y R Q +F+D+ S T F
Sbjct: 144 EPVQTLDEARDGVSSVKVLDHEILAGSVDGRVRRYDLRMGQ---LFSDYVGSPITCTCFS 200
Query: 477 KNAQYLASTSMDRTLKL 493
++ Q +S+D TL+L
Sbjct: 201 RDGQCTLVSSLDSTLRL 217
Score = 52.4 bits (120), Expect = 4e-06
Identities = 49/231 (21%), Positives = 92/231 (39%), Gaps = 10/231 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + LT G+D+ ++N ++ GH +V D ++ + D + +W+
Sbjct: 36 DGNYCLTCGSDKTLKLWNPLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWD 95
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH---WAFSDIRTGQLLTKVSDFSG 342
V + Q R H G V + + +LS S D W R + T G
Sbjct: 96 VASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDG 155
Query: 343 VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATA 402
VS H G+ + +V+ +DL+ +++ G P+T FS +G +
Sbjct: 156 VSSVKVLDHE----ILAGSVDGRVRRYDLRMGQLFSDYVG--SPITCTCFSRDGQCTLVS 209
Query: 403 AEDSCVKLWDLRKLKNFKTIQLEENYAIK-ELCFDQSGTYLAIAGTDVRVY 452
+ DS ++L D + + +N K + C + T++ D +V+
Sbjct: 210 SLDSTLRLLDKDTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVF 260
Score = 39.5 bits (88), Expect = 0.027
Identities = 26/112 (23%), Positives = 47/112 (41%), Gaps = 3/112 (2%)
Query: 385 GPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAI 444
G V ++ F+ +G Y T D +KLW+ + +T Y + + + L
Sbjct: 26 GAVRAVRFNVDGNYCLTCGSDKTLKLWNPLRGTLLRTYS-GHGYEVLDAAGSFDNSSLCS 84
Query: 445 AGTDVRVYL--CRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
G D V L Q ++ F H V+F + A + S S+D +++ +
Sbjct: 85 GGGDKAVVLWDVASGQVVRKFRGHAGKVNTVQFNEEATVILSGSIDSSIRCW 136
>AK095312-1|BAC04527.1| 895|Homo sapiens protein ( Homo sapiens
cDNA FLJ37993 fis, clone CTONG2011815. ).
Length = 895
Score = 69.3 bits (162), Expect = 3e-11
Identities = 70/273 (25%), Positives = 123/273 (45%), Gaps = 19/273 (6%)
Query: 234 GNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTA 293
GN +A NK+ +V KGH ++ P D +I+ D + +W++ S+
Sbjct: 86 GNVFSAFARNKE---IVHTFKGHKAEIH--FLQPFGDHIISVDTDGILIIWHI-YSEEEY 139
Query: 294 ILRSHDGPVTGLS--LHPTG--DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
+ + D V +S LHP+ + +L S ++++ +LL + V +T Q
Sbjct: 140 LQLTFDKSVFKISAILHPSTYLNKILLGSEQGSLQLWNVKSNKLLYTFPGWK-VGVTALQ 198
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY-YLATAAEDSCV 408
P + G + QV I ++K + F GP+TSISF +G+ +A + +
Sbjct: 199 QAPAVDVVAVGLMSGQVIIHNIKFNETLMKFRQDWGPITSISFRTDGHPVMAAGSPCGHI 258
Query: 409 KLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL----CRQWQELKV 462
LWDL K ++ + AI L F L G D +R+++ + + L+
Sbjct: 259 GLWDLEDKKLINQMRNAHSTAIAGLTFLHREPLLVTNGADNALRIWIFDGPTGEGRLLRF 318
Query: 463 FNDHTASATGVR-FGKNAQYLASTSMDRTLKLY 494
H+A T +R +G+N Q + S S D TL+ +
Sbjct: 319 RMGHSAPLTNIRYYGQNGQQILSASQDGTLQSF 351
Score = 58.8 bits (136), Expect = 4e-08
Identities = 40/170 (23%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 296 RSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGL 355
++H G V G+++ ++T S+ F + + L+ VS S ++ H D
Sbjct: 480 QAHKGSVRGVAVDGLNQLTVTTGSEGLLKFWNFKNKILIHSVSLSSSPNIML--LHRDSG 537
Query: 356 IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRK 415
I G ++ + + D++ + V F GH G + ++FS +G +L +AA D ++ WDL
Sbjct: 538 ILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAMDCSIRTWDLPS 597
Query: 416 LKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-VRVYLCRQWQELKVFN 464
L+ A + +G +LA + D + +YL W + +++
Sbjct: 598 GCLIDCFLLDS--APLNVSMSPTGDFLATSHVDHLGIYL---WSNISLYS 642
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 2/114 (1%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
+HS S+ ++ + D L +D + +V + +T ++V GH ++ + + PD
Sbjct: 518 IHSVSLSSSPNIMLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPD 577
Query: 269 EDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH 322
+I+A+ D +IR W++P+ P+ +S+ PTGD+ L+TS H
Sbjct: 578 GRWLISAAMDCSIRTWDLPSGCLIDCFLLDSAPL-NVSMSPTGDF-LATSHVDH 629
Score = 32.7 bits (71), Expect = 3.1
Identities = 23/140 (16%), Positives = 56/140 (40%), Gaps = 3/140 (2%)
Query: 360 GTENSQVKIWDLKEQSNVANF---PGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKL 416
G + V +++++ + +F H G V ++ T + +K W+ +
Sbjct: 456 GLSSGTVDVYNMQSGIHRGSFGKDQAHKGSVRGVAVDGLNQLTVTTGSEGLLKFWNFKNK 515
Query: 417 KNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFG 476
++ L + I L D LA+ + V + ++ F+ H + F
Sbjct: 516 ILIHSVSLSSSPNIMLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFS 575
Query: 477 KNAQYLASTSMDRTLKLYGI 496
+ ++L S +MD +++ + +
Sbjct: 576 PDGRWLISAAMDCSIRTWDL 595
Score = 31.1 bits (67), Expect = 9.3
Identities = 16/72 (22%), Positives = 33/72 (45%)
Query: 263 VIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH 322
++ H D + A D +I V ++ T + H G + ++ P G +++S + D
Sbjct: 530 MLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAMDCS 589
Query: 323 WAFSDIRTGQLL 334
D+ +G L+
Sbjct: 590 IRTWDLPSGCLI 601
>BC133025-1|AAI33026.1| 951|Homo sapiens WD repeat domain 36
protein.
Length = 951
Score = 68.9 bits (161), Expect = 4e-11
Identities = 70/273 (25%), Positives = 123/273 (45%), Gaps = 19/273 (6%)
Query: 234 GNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTA 293
GN +A NK+ +V KGH ++ P D +I+ D + +W++ S+
Sbjct: 142 GNVFSAFARNKE---IVHTFKGHKAEIH--FLQPFGDHIISVDTDGILIIWHI-YSEEEY 195
Query: 294 ILRSHDGPVTGLS--LHPTG--DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
+ + D V +S LHP+ + +L S ++++ +LL + V +T Q
Sbjct: 196 LQLTFDKSVFKISAILHPSTYLNKILLGSEQGSLQLWNVKSNKLLYTFPGWK-VGVTALQ 254
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY-YLATAAEDSCV 408
P + G + QV I ++K + F GP+TSISF +G+ +A + +
Sbjct: 255 QAPAVDVVAIGLMSGQVIIHNIKFNETLMKFRQDWGPITSISFRTDGHPVMAAGSPCGHI 314
Query: 409 KLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL----CRQWQELKV 462
LWDL K ++ + AI L F L G D +R+++ + + L+
Sbjct: 315 GLWDLEDKKLINQMRNAHSTAIAGLTFLHREPLLVTNGADNALRIWIFDGPTGEGRLLRF 374
Query: 463 FNDHTASATGVR-FGKNAQYLASTSMDRTLKLY 494
H+A T +R +G+N Q + S S D TL+ +
Sbjct: 375 RMGHSAPLTNIRYYGQNGQQILSASQDGTLQSF 407
Score = 58.8 bits (136), Expect = 4e-08
Identities = 40/170 (23%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 296 RSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGL 355
++H G V G+++ ++T S+ F + + L+ VS S ++ H D
Sbjct: 536 QAHKGSVRGVAVDGLNQLTVTTGSEGLLKFWNFKNKILIHSVSLSSSPNIML--LHRDSG 593
Query: 356 IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRK 415
I G ++ + + D++ + V F GH G + ++FS +G +L +AA D ++ WDL
Sbjct: 594 ILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAMDCSIRTWDLPS 653
Query: 416 LKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-VRVYLCRQWQELKVFN 464
L+ A + +G +LA + D + +YL W + +++
Sbjct: 654 GCLIDCFLLDS--APLNVSMSPTGDFLATSHVDHLGIYL---WSNISLYS 698
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 2/114 (1%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
+HS S+ ++ + D L +D + +V + +T ++V GH ++ + + PD
Sbjct: 574 IHSVSLSSSPNIMLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPD 633
Query: 269 EDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH 322
+I+A+ D +IR W++P+ P+ +S+ PTGD+ L+TS H
Sbjct: 634 GRWLISAAMDCSIRTWDLPSGCLIDCFLLDSAPL-NVSMSPTGDF-LATSHVDH 685
Score = 32.7 bits (71), Expect = 3.1
Identities = 23/140 (16%), Positives = 56/140 (40%), Gaps = 3/140 (2%)
Query: 360 GTENSQVKIWDLKEQSNVANF---PGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKL 416
G + V +++++ + +F H G V ++ T + +K W+ +
Sbjct: 512 GLSSGTVDVYNMQSGIHRGSFGKDQAHKGSVRGVAVDGLNQLTVTTGSEGLLKFWNFKNK 571
Query: 417 KNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFG 476
++ L + I L D LA+ + V + ++ F+ H + F
Sbjct: 572 ILIHSVSLSSSPNIMLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFS 631
Query: 477 KNAQYLASTSMDRTLKLYGI 496
+ ++L S +MD +++ + +
Sbjct: 632 PDGRWLISAAMDCSIRTWDL 651
Score = 31.1 bits (67), Expect = 9.3
Identities = 16/72 (22%), Positives = 33/72 (45%)
Query: 263 VIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH 322
++ H D + A D +I V ++ T + H G + ++ P G +++S + D
Sbjct: 586 MLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAMDCS 645
Query: 323 WAFSDIRTGQLL 334
D+ +G L+
Sbjct: 646 IRTWDLPSGCLI 657
>AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating
factor-1 protein.
Length = 1205
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/261 (21%), Positives = 112/261 (42%), Gaps = 22/261 (8%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
+++ HT V R + D + + D T++V+ T + +++H+ V +
Sbjct: 610 VVRPHTDAVYRACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDD 669
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG----VSLTTAQFHPDGLIFGTGTENSQVK 367
++ + S D+ + TG+L+ + S T + H L+ TG+ + +K
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHH---LLLATGSSDCFLK 726
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEEN 427
+WDL ++ GH V FS + LA+ + D +KLWD K+I +++
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 428 Y-----------AIKELC-FDQSGTYLAIAGTDVRVYLCRQWQELKVFN--DHTASATGV 473
+ I + C + G + +A + +++L KV + H + GV
Sbjct: 787 FLNLEDPQEDMGVIVKCCSWSADGARIMVAAKN-KIFLWNTDLRSKVADCRGHLSWVHGV 845
Query: 474 RFGKNAQYLASTSMDRTLKLY 494
F + ++S D+T++L+
Sbjct: 846 MFSPDGSSFLTSSDDQTIRLW 866
Score = 55.2 bits (127), Expect = 5e-07
Identities = 54/198 (27%), Positives = 81/198 (40%), Gaps = 10/198 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H K V + + DE T+I++S D I+VWN + LR H V L +L
Sbjct: 959 HKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDK-CIFLRGHQETVKDFRL-LKNSRLL 1016
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
S S D +I TG G L+ H D F + + + KIW
Sbjct: 1017 SWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISH-DATKFSSTSADKTAKIWSFDLLL 1075
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLEENYA---- 429
+ GH G V +FS + LAT ++ +++W++ +L + EE A
Sbjct: 1076 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGG 1135
Query: 430 -IKELCFDQSGTYLAIAG 446
+ +LCF G L AG
Sbjct: 1136 WVTDLCFSPDGKMLISAG 1153
Score = 54.0 bits (124), Expect = 1e-06
Identities = 61/276 (22%), Positives = 117/276 (42%), Gaps = 14/276 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D ++++ ++ ++N D VA +GH V V++ PD + +T+S D TIR+W
Sbjct: 808 ADGARIMVAAKNK-IFLWNTDLRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 866
Query: 285 NVP-TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQL--LTKVSDFS 341
+ +A++ + V VL+ + + RTGQ+ LT+
Sbjct: 867 ETKKVCKNSAVMLKQEVDVV---FQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQ--- 920
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
VS H + FG EN ++I +L + H V I F+ + L +
Sbjct: 921 -VSCCCLSPHLQYIAFGD--ENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
+++D+ +++W+ + K +E L + + GT V+V+ + K
Sbjct: 978 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGT-VKVWNIITGNKEK 1036
Query: 462 VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
F H + +A +STS D+T K++ +
Sbjct: 1037 DFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 52.0 bits (119), Expect = 5e-06
Identities = 43/216 (19%), Positives = 91/216 (42%), Gaps = 15/216 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVI--TASPDHTIR 282
+D + T D+ ++N T ++V H+++V + ++ T S D ++
Sbjct: 667 TDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSD------IRTGQL 333
+W++ + + H V P + S S+D + W + I Q
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 334 LTKVSDFS---GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
+ D GV + + DG +N ++ +W+ +S VA+ GH+ V +
Sbjct: 787 FLNLEDPQEDMGVIVKCCSWSADGARIMVAAKN-KIFLWNTDLRSKVADCRGHLSWVHGV 845
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEE 426
FS +G T+++D ++LW+ +K+ + L++
Sbjct: 846 MFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ 881
Score = 47.6 bits (108), Expect = 1e-04
Identities = 30/147 (20%), Positives = 62/147 (42%), Gaps = 3/147 (2%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++ + G D+ VF +T + + +K H +V + D+ + T S D +++WN
Sbjct: 626 DGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN 685
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVL--STSSDQHWAFSDIRTGQLLTKVSDFSGV 343
T + H V + ++L + SSD D+ + + +
Sbjct: 686 SMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTN- 744
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWD 370
S+ +F PD + + + + +K+WD
Sbjct: 745 SVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 39.9 bits (89), Expect = 0.020
Identities = 35/166 (21%), Positives = 76/166 (45%), Gaps = 19/166 (11%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
N S H L TG +D +++ + ++ + GHT V + PD+ + + S D T++
Sbjct: 709 NSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLK 768
Query: 283 VWNVPTSQTTAILR------SHDGP-------VTGLSLHPTGDYVLSTSSDQHWAFSDIR 329
+W+ ++ + + + P V S G ++ + ++ + ++
Sbjct: 769 LWDATSANERKSINVKQFFLNLEDPQEDMGVIVKCCSWSADGARIMVAAKNKIFLWNT-- 826
Query: 330 TGQLLTKVSDFSG-VS-LTTAQFHPDGLIFGTGTENSQVKIWDLKE 373
L +KV+D G +S + F PDG F T +++ +++W+ K+
Sbjct: 827 --DLRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 38.3 bits (85), Expect = 0.062
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 9/115 (7%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+LS DI+ D +K + D+ A +++ D + L+GH V + D + T
Sbjct: 1045 VLSCDIS-HDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 277 PDHTIRVWNVPTSQTTAI--------LRSHDGPVTGLSLHPTGDYVLSTSSDQHW 323
+ IR+WNV + + +H G VT L P G ++S W
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKW 1158
>AF385437-1|AAM43838.1| 951|Homo sapiens T-cell activation WD
repeat protein protein.
Length = 951
Score = 68.9 bits (161), Expect = 4e-11
Identities = 70/273 (25%), Positives = 123/273 (45%), Gaps = 19/273 (6%)
Query: 234 GNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTA 293
GN +A NK+ +V KGH ++ P D +I+ D + +W++ S+
Sbjct: 142 GNVFSAFARNKE---IVHTFKGHKAEIH--FLQPFGDHIISVDTDGILIIWHI-YSEEEY 195
Query: 294 ILRSHDGPVTGLS--LHPTG--DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQ 349
+ + D V +S LHP+ + +L S ++++ +LL + V +T Q
Sbjct: 196 LQLTFDKSVFKISAILHPSTYLNKILLGSEQGSLQLWNVKSNKLLYTFPGWK-VGVTALQ 254
Query: 350 FHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGY-YLATAAEDSCV 408
P + G + QV I ++K + F GP+TSISF +G+ +A + +
Sbjct: 255 QAPAVDVVAIGLMSGQVIIHNIKFNETLMKFRQDWGPITSISFRTDGHPVMAAGSPCGHI 314
Query: 409 KLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD--VRVYL----CRQWQELKV 462
LWDL K ++ + AI L F L G D +R+++ + + L+
Sbjct: 315 GLWDLEDKKLINQMRNAHSTAIAGLTFLHREPLLVTNGADNALRIWIFDGPTGEGRLLRF 374
Query: 463 FNDHTASATGVR-FGKNAQYLASTSMDRTLKLY 494
H+A T +R +G+N Q + S S D TL+ +
Sbjct: 375 RMGHSAPLTNIRYYGQNGQQILSASQDGTLQSF 407
Score = 58.8 bits (136), Expect = 4e-08
Identities = 40/170 (23%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 296 RSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGL 355
++H G V G+++ ++T S+ F + + L+ VS S ++ H D
Sbjct: 536 QAHKGSVRGVAVDGLNQLTVTTGSEGLLKFWNFKNKILIHSVSLSSSPNIML--LHRDSG 593
Query: 356 IFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRK 415
I G ++ + + D++ + V F GH G + ++FS +G +L +AA D ++ WDL
Sbjct: 594 ILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAMDCSIRTWDLPS 653
Query: 416 LKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-VRVYLCRQWQELKVFN 464
L+ A + +G +LA + D + +YL W + +++
Sbjct: 654 GCLIDCFLLDS--APLNVSMSPTGDFLATSHVDHLGIYL---WSNISLYS 698
Score = 49.6 bits (113), Expect = 2e-05
Identities = 30/114 (26%), Positives = 58/114 (50%), Gaps = 2/114 (1%)
Query: 209 LHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPD 268
+HS S+ ++ + D L +D + +V + +T ++V GH ++ + + PD
Sbjct: 574 IHSVSLSSSPNIMLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPD 633
Query: 269 EDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH 322
+I+A+ D +IR W++P+ P+ +S+ PTGD+ L+TS H
Sbjct: 634 GRWLISAAMDCSIRTWDLPSGCLIDCFLLDSAPL-NVSMSPTGDF-LATSHVDH 685
Score = 32.7 bits (71), Expect = 3.1
Identities = 23/140 (16%), Positives = 56/140 (40%), Gaps = 3/140 (2%)
Query: 360 GTENSQVKIWDLKEQSNVANF---PGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKL 416
G + V +++++ + +F H G V ++ T + +K W+ +
Sbjct: 512 GLSSGTVDVYNMQSGIHRGSFGKDQAHKGSVRGVAVDGLNQLTVTTGSEGLLKFWNFKNK 571
Query: 417 KNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELKVFNDHTASATGVRFG 476
++ L + I L D LA+ + V + ++ F+ H + F
Sbjct: 572 ILIHSVSLSSSPNIMLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFS 631
Query: 477 KNAQYLASTSMDRTLKLYGI 496
+ ++L S +MD +++ + +
Sbjct: 632 PDGRWLISAAMDCSIRTWDL 651
Score = 31.1 bits (67), Expect = 9.3
Identities = 16/72 (22%), Positives = 33/72 (45%)
Query: 263 VIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH 322
++ H D + A D +I V ++ T + H G + ++ P G +++S + D
Sbjct: 586 MLLHRDSGILGLALDDFSISVLDIETRKIVREFSGHQGQINDMAFSPDGRWLISAAMDCS 645
Query: 323 WAFSDIRTGQLL 334
D+ +G L+
Sbjct: 646 IRTWDLPSGCLI 657
>BC108280-1|AAI08281.1| 896|Homo sapiens echinoderm microtubule
associated protein like 3 protein.
Length = 896
Score = 68.5 bits (160), Expect = 5e-11
Identities = 49/201 (24%), Positives = 96/201 (47%), Gaps = 15/201 (7%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S+LL G +NA + + +++GHT ++ + HP ++ +T D + +W+
Sbjct: 569 SELLVG-TTKNALLRGDLAQGFSPVIQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWD-- 625
Query: 288 TSQTTAILRSHDGPVTGL--SLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
++ A+ S D TGL HP+G V + W D T ++++ V D L
Sbjct: 626 -GESHALAWSIDLKETGLCADFHPSGAVVAVGLNTGRWLVLDTETREIVSDVID-GNEQL 683
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW----DLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
+ ++ PDGL G+ ++ + I+ D + S GH +T + +S++G ++ +
Sbjct: 684 SVVRYSPDGLYLAIGSHDNVIYIYSVSSDGAKSSRFGRCMGHSSFITHLDWSKDGNFIMS 743
Query: 402 AAEDSCVKLWDL----RKLKN 418
+ D + WD+ ++LKN
Sbjct: 744 NSGDYEILYWDVAGGCKQLKN 764
>BC021110-1|AAH21110.1| 421|Homo sapiens WD repeat and SOCS
box-containing 1 protein.
Length = 421
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/243 (23%), Positives = 103/243 (42%), Gaps = 21/243 (8%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV-ITASPDHTIRVW 284
D L TG N+ +++ T +++ L HT+ V + + PD + ++AS D T+RVW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 285 NV-PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV 343
++ +LR H V + P + S + + ++ ++ K+
Sbjct: 199 DLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHH- 257
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGP--------------VTS 389
+ F PDG + T + +++V IWD + F GH+ P V S
Sbjct: 258 DVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRS 316
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDV 449
+SFS +G ++A+ A+D V+ W + + + L F G+ LA D
Sbjct: 317 VSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC---CAFSTDGSVLAAGTHDG 373
Query: 450 RVY 452
VY
Sbjct: 374 SVY 376
Score = 57.6 bits (133), Expect = 9e-08
Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 262 RVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-STSSD 320
R + D+ + T + I++W+V T + L H V L+ P G +L S S D
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRD 192
Query: 321 QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANF 380
+ D++ + KV + + F PD + + + V +W++ + + +
Sbjct: 193 KTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL 252
Query: 381 PGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
GH V + FS +G LATA+ D+ V +WD
Sbjct: 253 EGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 56.4 bits (130), Expect = 2e-07
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG-YYLATAAEDSC 407
+F D L+ TG N ++KIWD+ + N H V ++F+ +G L +A+ D
Sbjct: 135 RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKT 194
Query: 408 VKLWDLRKLKN-FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR--QWQELKVFN 464
+++WDL+ N K ++ +N+ + F + L G V+L ++ ++
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNW-VYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 253
Query: 465 DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
H F + LA+ S D + ++
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIW 283
Score = 53.2 bits (122), Expect = 2e-06
Identities = 45/211 (21%), Positives = 81/211 (38%), Gaps = 21/211 (9%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
+ L P L++ D+ V++ KD ++ +L+GH V + PD + +
Sbjct: 173 VRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSV 232
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
+ +WN+ L H V P G + + S D D G +L
Sbjct: 233 GASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
Query: 336 KVSD--------FSGVS----LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGH 383
+ F+G + + + F DGL + ++ V+ W + E ++P
Sbjct: 293 EFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDE-----DYPVQ 347
Query: 384 VGPVTS---ISFSENGYYLATAAEDSCVKLW 411
V P+++ +FS +G LA D V W
Sbjct: 348 VAPLSNGLCCAFSTDGSVLAAGTHDGSVYFW 378
>AK128679-1|BAC87566.1| 780|Homo sapiens protein ( Homo sapiens
cDNA FLJ46843 fis, clone UTERU3001029, moderately
similar to Echinoderm microtubule-associated protein. ).
Length = 780
Score = 68.5 bits (160), Expect = 5e-11
Identities = 49/201 (24%), Positives = 96/201 (47%), Gaps = 15/201 (7%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S+LL G +NA + + +++GHT ++ + HP ++ +T D + +W+
Sbjct: 453 SELLVG-TTKNALLRGDLAQGFSPVIQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWD-- 509
Query: 288 TSQTTAILRSHDGPVTGL--SLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
++ A+ S D TGL HP+G V + W D T ++++ V D L
Sbjct: 510 -GESHALAWSIDLKETGLCADFHPSGAVVAVGLNTGRWLVLDTETREIVSDVID-GNEQL 567
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW----DLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
+ ++ PDGL G+ ++ + I+ D + S GH +T + +S++G ++ +
Sbjct: 568 SVVRYSPDGLYLAIGSHDNVIYIYSVSSDGAKSSRFGRCMGHSSFITHLDWSKDGNFIMS 627
Query: 402 AAEDSCVKLWDL----RKLKN 418
+ D + WD+ ++LKN
Sbjct: 628 NSGDYEILYWDVAGGCKQLKN 648
>AK093146-1|BAC04073.1| 889|Homo sapiens protein ( Homo sapiens
cDNA FLJ35827 fis, clone TESTI2006453, weakly similar to
Microtubule-associated protein like echinoderm EMAP. ).
Length = 889
Score = 68.5 bits (160), Expect = 5e-11
Identities = 49/201 (24%), Positives = 96/201 (47%), Gaps = 15/201 (7%)
Query: 228 SKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVP 287
S+LL G +NA + + +++GHT ++ + HP ++ +T D + +W+
Sbjct: 541 SELLVG-TTKNALLRGDLAQGFSPVIQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWD-- 597
Query: 288 TSQTTAILRSHDGPVTGL--SLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSL 345
++ A+ S D TGL HP+G V + W D T ++++ V D L
Sbjct: 598 -GESHALAWSIDLKETGLCADFHPSGAVVAVGLNTGRWLVLDTETREIVSDVID-GNEQL 655
Query: 346 TTAQFHPDGLIFGTGTENSQVKIW----DLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
+ ++ PDGL G+ ++ + I+ D + S GH +T + +S++G ++ +
Sbjct: 656 SVVRYSPDGLYLAIGSHDNVIYIYSVSSDGAKSSRFGRCMGHSSFITHLDWSKDGNFIMS 715
Query: 402 AAEDSCVKLWDL----RKLKN 418
+ D + WD+ ++LKN
Sbjct: 716 NSGDYEILYWDVAGGCKQLKN 736
>AK074917-1|BAC11291.1| 421|Homo sapiens protein ( Homo sapiens
cDNA FLJ90436 fis, clone NT2RP3000820, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC
2.7.1.-). ).
Length = 421
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/243 (23%), Positives = 103/243 (42%), Gaps = 21/243 (8%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV-ITASPDHTIRVW 284
D L TG N+ +++ T +++ L HT+ V + + PD + ++AS D T+RVW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 285 NV-PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV 343
++ +LR H V + P + S + + ++ ++ K+
Sbjct: 199 DLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHH- 257
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGP--------------VTS 389
+ F PDG + T + +++V IWD + F GH+ P V S
Sbjct: 258 DVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRS 316
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDV 449
+SFS +G ++A+ A+D V+ W + + + L F G+ LA D
Sbjct: 317 VSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC---CAFSTDGSVLAAGTHDG 373
Query: 450 RVY 452
VY
Sbjct: 374 SVY 376
Score = 57.6 bits (133), Expect = 9e-08
Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 262 RVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-STSSD 320
R + D+ + T + I++W+V T + L H V L+ P G +L S S D
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRD 192
Query: 321 QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANF 380
+ D++ + KV + + F PD + + + V +W++ + + +
Sbjct: 193 KTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL 252
Query: 381 PGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
GH V + FS +G LATA+ D+ V +WD
Sbjct: 253 EGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 56.4 bits (130), Expect = 2e-07
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG-YYLATAAEDSC 407
+F D L+ TG N ++KIWD+ + N H V ++F+ +G L +A+ D
Sbjct: 135 RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKT 194
Query: 408 VKLWDLRKLKN-FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR--QWQELKVFN 464
+++WDL+ N K ++ +N+ + F + L G V+L ++ ++
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNW-VYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 253
Query: 465 DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
H F + LA+ S D + ++
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIW 283
Score = 53.2 bits (122), Expect = 2e-06
Identities = 45/211 (21%), Positives = 81/211 (38%), Gaps = 21/211 (9%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
+ L P L++ D+ V++ KD ++ +L+GH V + PD + +
Sbjct: 173 VRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSV 232
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
+ +WN+ L H V P G + + S D D G +L
Sbjct: 233 GASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
Query: 336 KVSD--------FSGVS----LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGH 383
+ F+G + + + F DGL + ++ V+ W + E ++P
Sbjct: 293 EFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDE-----DYPVQ 347
Query: 384 VGPVTS---ISFSENGYYLATAAEDSCVKLW 411
V P+++ +FS +G LA D V W
Sbjct: 348 VAPLSNGLCCAFSTDGSVLAAGTHDGSVYFW 378
>AF112205-1|AAF17193.1| 421|Homo sapiens WSB-1 protein protein.
Length = 421
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/243 (23%), Positives = 103/243 (42%), Gaps = 21/243 (8%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV-ITASPDHTIRVW 284
D L TG N+ +++ T +++ L HT+ V + + PD + ++AS D T+RVW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 285 NV-PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV 343
++ +LR H V + P + S + + ++ ++ K+
Sbjct: 199 DLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHH- 257
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGP--------------VTS 389
+ F PDG + T + +++V IWD + F GH+ P V S
Sbjct: 258 DVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRS 316
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDV 449
+SFS +G ++A+ A+D V+ W + + + L F G+ LA D
Sbjct: 317 VSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC---CAFSTDGSVLAAGTHDG 373
Query: 450 RVY 452
VY
Sbjct: 374 SVY 376
Score = 57.6 bits (133), Expect = 9e-08
Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 262 RVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-STSSD 320
R + D+ + T + I++W+V T + L H V L+ P G +L S S D
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRD 192
Query: 321 QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANF 380
+ D++ + KV + + F PD + + + V +W++ + + +
Sbjct: 193 KTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL 252
Query: 381 PGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
GH V + FS +G LATA+ D+ V +WD
Sbjct: 253 EGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 56.4 bits (130), Expect = 2e-07
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG-YYLATAAEDSC 407
+F D L+ TG N ++KIWD+ + N H V ++F+ +G L +A+ D
Sbjct: 135 RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKT 194
Query: 408 VKLWDLRKLKN-FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR--QWQELKVFN 464
+++WDL+ N K ++ +N+ + F + L G V+L ++ ++
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNW-VYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 253
Query: 465 DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
H F + LA+ S D + ++
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIW 283
Score = 53.2 bits (122), Expect = 2e-06
Identities = 45/211 (21%), Positives = 81/211 (38%), Gaps = 21/211 (9%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
+ L P L++ D+ V++ KD ++ +L+GH V + PD + +
Sbjct: 173 VRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSV 232
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
+ +WN+ L H V P G + + S D D G +L
Sbjct: 233 GASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
Query: 336 KVSD--------FSGVS----LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGH 383
+ F+G + + + F DGL + ++ V+ W + E ++P
Sbjct: 293 EFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDE-----DYPVQ 347
Query: 384 VGPVTS---ISFSENGYYLATAAEDSCVKLW 411
V P+++ +FS +G LA D V W
Sbjct: 348 VAPLSNGLCCAFSTDGSVLAAGTHDGSVYFW 378
>AF072880-1|AAD28808.1| 421|Homo sapiens SOCS box-containing WD
protein SWiP-1 protein.
Length = 421
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/243 (23%), Positives = 103/243 (42%), Gaps = 21/243 (8%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV-ITASPDHTIRVW 284
D L TG N+ +++ T +++ L HT+ V + + PD + ++AS D T+RVW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 285 NV-PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV 343
++ +LR H V + P + S + + ++ ++ K+
Sbjct: 199 DLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHH- 257
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGP--------------VTS 389
+ F PDG + T + +++V IWD + F GH+ P V S
Sbjct: 258 DVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRS 316
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDV 449
+SFS +G ++A+ A+D V+ W + + + L F G+ LA D
Sbjct: 317 VSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC---CAFSTDGSVLAAGTHDG 373
Query: 450 RVY 452
VY
Sbjct: 374 SVY 376
Score = 57.6 bits (133), Expect = 9e-08
Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 262 RVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-STSSD 320
R + D+ + T + I++W+V T + L H V L+ P G +L S S D
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRD 192
Query: 321 QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANF 380
+ D++ + KV + + F PD + + + V +W++ + + +
Sbjct: 193 KTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL 252
Query: 381 PGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
GH V + FS +G LATA+ D+ V +WD
Sbjct: 253 EGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 56.4 bits (130), Expect = 2e-07
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG-YYLATAAEDSC 407
+F D L+ TG N ++KIWD+ + N H V ++F+ +G L +A+ D
Sbjct: 135 RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKT 194
Query: 408 VKLWDLRKLKN-FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR--QWQELKVFN 464
+++WDL+ N K ++ +N+ + F + L G V+L ++ ++
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNW-VYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 253
Query: 465 DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
H F + LA+ S D + ++
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIW 283
Score = 53.2 bits (122), Expect = 2e-06
Identities = 45/211 (21%), Positives = 81/211 (38%), Gaps = 21/211 (9%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
+ L P L++ D+ V++ KD ++ +L+GH V + PD + +
Sbjct: 173 VRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSV 232
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
+ +WN+ L H V P G + + S D D G +L
Sbjct: 233 GASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
Query: 336 KVSD--------FSGVS----LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGH 383
+ F+G + + + F DGL + ++ V+ W + E ++P
Sbjct: 293 EFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDE-----DYPVQ 347
Query: 384 VGPVTS---ISFSENGYYLATAAEDSCVKLW 411
V P+++ +FS +G LA D V W
Sbjct: 348 VAPLSNGLCCAFSTDGSVLAAGTHDGSVYFW 378
>AF069313-1|AAD20954.2| 421|Homo sapiens WSB1 protein protein.
Length = 421
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/243 (23%), Positives = 103/243 (42%), Gaps = 21/243 (8%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV-ITASPDHTIRVW 284
D L TG N+ +++ T +++ L HT+ V + + PD + ++AS D T+RVW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 285 NV-PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV 343
++ +LR H V + P + S + + ++ ++ K+
Sbjct: 199 DLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHH- 257
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGP--------------VTS 389
+ F PDG + T + +++V IWD + F GH+ P V S
Sbjct: 258 DVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRS 316
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDV 449
+SFS +G ++A+ A+D V+ W + + + L F G+ LA D
Sbjct: 317 VSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC---CAFSTDGSVLAAGTHDG 373
Query: 450 RVY 452
VY
Sbjct: 374 SVY 376
Score = 57.6 bits (133), Expect = 9e-08
Identities = 39/152 (25%), Positives = 69/152 (45%), Gaps = 1/152 (0%)
Query: 262 RVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-STSSD 320
R + D+ + T + I++W+V T + L H V L+ P G +L S S D
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRD 192
Query: 321 QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANF 380
+ D++ + KV + + F PD + + + V +W++ + + +
Sbjct: 193 KTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL 252
Query: 381 PGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
GH V + FS +G LATA+ D+ V +WD
Sbjct: 253 EGHHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 56.4 bits (130), Expect = 2e-07
Identities = 35/150 (23%), Positives = 67/150 (44%), Gaps = 5/150 (3%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG-YYLATAAEDSC 407
+F D L+ TG N ++KIWD+ + N H V ++F+ +G L +A+ D
Sbjct: 135 RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKT 194
Query: 408 VKLWDLRKLKN-FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR--QWQELKVFN 464
+++WDL+ N K ++ +N+ + F + L G V+L ++ ++
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNW-VYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 253
Query: 465 DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
H F + LA+ S D + ++
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIW 283
Score = 53.2 bits (122), Expect = 2e-06
Identities = 45/211 (21%), Positives = 81/211 (38%), Gaps = 21/211 (9%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
+ L P L++ D+ V++ KD ++ +L+GH V + PD + +
Sbjct: 173 VRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSV 232
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
+ +WN+ L H V P G + + S D D G +L
Sbjct: 233 GASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
Query: 336 KVSD--------FSGVS----LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGH 383
+ F+G + + + F DGL + ++ V+ W + E ++P
Sbjct: 293 EFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDE-----DYPVQ 347
Query: 384 VGPVTS---ISFSENGYYLATAAEDSCVKLW 411
V P+++ +FS +G LA D V W
Sbjct: 348 VAPLSNGLCCAFSTDGSVLAAGTHDGSVYFW 378
>AB209111-1|BAD92348.1| 487|Homo sapiens Notchless gene homolog
variant protein.
Length = 487
Score = 68.1 bits (159), Expect = 7e-11
Identities = 41/175 (23%), Positives = 79/175 (45%), Gaps = 4/175 (2%)
Query: 239 ATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILR-- 296
A+V +D + + LK ++ + +++ S D T+ +W+ P + R
Sbjct: 313 ASVNPQDLQGFLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWS-PAEDKKPLTRMT 371
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLI 356
H + + P V S S D+ D RTG+ L + A + D +
Sbjct: 372 GHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIA-WSADSRL 430
Query: 357 FGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
+G+ +S +K+WD+K Q + PGH V ++ +S +G +A+ +D C+++W
Sbjct: 431 LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 485
Score = 64.1 bits (149), Expect = 1e-09
Identities = 73/308 (23%), Positives = 128/308 (41%), Gaps = 16/308 (5%)
Query: 196 QIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKG 255
++RA S HS +V +S+ +P+ L +G D ++ TE KG
Sbjct: 101 RVRAVTRCTSSLEGHSEAV---ISVAFSPTG-KYLASGSGDTTVRFWDLSTETPHFTCKG 156
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT-SQTTAILRSHDGPVTGLS---LH--P 309
H V + + PD + + + I +W+ T Q L H +TGLS LH P
Sbjct: 157 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANP 216
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
YV S+S D D G+ ++ S+T ++ DGL++ + +++ +K+W
Sbjct: 217 ECRYVASSSKDGSVRIWDTTAGR-CERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVW 274
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+ GH V +++ S + Y L T A + + + L+ F E +
Sbjct: 275 RAHDGVLCRTLQGHGHWVNTMALSTD-YALRTGAFEPAEASVNPQDLQGFLQELKERALS 333
Query: 430 IKELCFDQSGTYLAIAGTDVRVYLCRQWQELKV---FNDHTASATGVRFGKNAQYLASTS 486
L Q L D ++L ++ K H A V F +++ +AS S
Sbjct: 334 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 393
Query: 487 MDRTLKLY 494
D+++KL+
Sbjct: 394 FDKSIKLW 401
Score = 59.3 bits (137), Expect = 3e-08
Identities = 65/294 (22%), Positives = 126/294 (42%), Gaps = 17/294 (5%)
Query: 210 HSASVPGIL--SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP 267
HS + G+ L NP + + + D + +++ + IL GHT+ VT + +
Sbjct: 200 HSKWITGLSWEPLHANP-ECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGG 258
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS- 326
D + +AS D TI+VW L+ H V ++L + DY L T + + S
Sbjct: 259 D-GLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMAL--STDYALRTGAFEPAEASV 315
Query: 327 ---DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN-VANFPG 382
D++ K S +L Q P+ L+ +G+++ + +W E + G
Sbjct: 316 NPQDLQGFLQELKERALSRYNLVRGQ-GPERLV--SGSDDFTLFLWSPAEDKKPLTRMTG 372
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H + + FS + +A+A+ D +KLWD R K +++ A+ ++ + L
Sbjct: 373 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLR-GHVAAVYQIAWSADSRLL 431
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+D ++V+ + + H V + + Q +AS D+ L+++
Sbjct: 432 VSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 485
Score = 49.6 bits (113), Expect = 2e-05
Identities = 60/289 (20%), Positives = 118/289 (40%), Gaps = 11/289 (3%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIY-----HPDED 270
+LS+ +P D KL +G + +++ T +QV L GH+K +T + + +P+
Sbjct: 161 VLSISWSP-DGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECR 219
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
V ++S D ++R+W+ + IL H VT L G + S S D+
Sbjct: 220 YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 278
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G +L + G + T D + E ++ + Q + ++
Sbjct: 279 G-VLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGFLQELKERALSRYNL 337
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-- 448
+ L + ++D + LW + K T I ++ F +A A D
Sbjct: 338 VRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKS 397
Query: 449 VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++++ R + L H A+ + + +++ L S S D TLK++ ++
Sbjct: 398 IKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 446
>BC026213-1|AAH26213.1| 529|Homo sapiens F-box and WD repeat domain
containing 11 protein.
Length = 529
Score = 67.7 bits (158), Expect = 9e-11
Identities = 45/190 (23%), Positives = 89/190 (46%), Gaps = 10/190 (5%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D K+++G D + +++K + + + +L GHT V + Y DE ++T S D T+RVW+
Sbjct: 236 DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWD 293
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDI--RTGQLLTKVSDFSGV 343
V T + L H+ V L L + +++ S D+ A D+ T L +V
Sbjct: 294 VNTGEVLNTLIHHNEAV--LHLRFSNGLMVTCSKDRSIAVWDMASATDITLRRVLVGHRA 351
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAA 403
++ F ++ +G + +K+W V GH + + + + + + +
Sbjct: 352 AVNVVDFDDKYIVSASG--DRTIKVWSTSTCEFVRTLNGHKRGIACLQYRDR--LVVSGS 407
Query: 404 EDSCVKLWDL 413
D+ ++LWD+
Sbjct: 408 SDNTIRLWDI 417
Score = 53.2 bits (122), Expect = 2e-06
Identities = 41/190 (21%), Positives = 89/190 (46%), Gaps = 8/190 (4%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++TG +D V++ +T +V+ L H + V + + ++T S D +I VW+
Sbjct: 276 DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNEAVLHLRF--SNGLMVTCSKDRSIAVWD 333
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGD-YVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVS 344
+ ++ + R G +++ D Y++S S D+ T + + ++
Sbjct: 334 MASATDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWSTSTCEFVRTLNGHKR-G 392
Query: 345 LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAE 404
+ Q+ D L+ +G+ ++ +++WD++ + + GH V I F + + A
Sbjct: 393 IACLQYR-DRLVV-SGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNK--RIVSGAY 448
Query: 405 DSCVKLWDLR 414
D +K+WDL+
Sbjct: 449 DGKIKVWDLQ 458
>BC015920-1|AAH15920.1| 297|Homo sapiens GNB3 protein protein.
Length = 297
Score = 67.7 bits (158), Expect = 9e-11
Identities = 58/250 (23%), Positives = 110/250 (44%), Gaps = 12/250 (4%)
Query: 253 LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGD 312
L+GH K+ + + D +++AS D + VW+ T+ + V + P+G+
Sbjct: 51 LRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN 110
Query: 313 YVLSTSSDQHWAFSDIRTGQLLTKVS-DFSGVS--LTTAQFHPDGLIFGTGTENSQVKIW 369
+V D + ++++ + KVS + S + L+ +F D I T + ++ +W
Sbjct: 111 FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIV-TSSGDTTCALW 169
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
D++ F GH G S++ S + + A D+ KLWD+R+ +T E+
Sbjct: 170 DIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES-D 228
Query: 430 IKELCFDQSGTYLAIAGTDVRVYLCRQWQELK-----VFNDHTASATGVRFGKNAQYLAS 484
I +CF L AG D + C W +K + + H + + + +A+
Sbjct: 229 INAICFFSLSGRLLFAGYD--DFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVAT 286
Query: 485 TSMDRTLKLY 494
S D LK++
Sbjct: 287 GSWDSFLKIW 296
Score = 67.7 bits (158), Expect = 9e-11
Identities = 43/184 (23%), Positives = 80/184 (43%), Gaps = 5/184 (2%)
Query: 233 GGNDRNATVFN-KDTEQVVAI---LKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT 288
GG D +++N K E V + L HT ++ + D++ ++T+S D T +W++ T
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFL-DDNNIVTSSGDTTCALWDIET 173
Query: 289 SQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTA 348
Q + H G L++ P + +S + D D+R G +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCV 408
F G + G ++ +WD + V GH V+ + + +G +AT + DS +
Sbjct: 234 FFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRVSCLGVTADGMAVATGSWDSFL 293
Query: 409 KLWD 412
K+W+
Sbjct: 294 KIWN 297
Score = 41.5 bits (93), Expect = 0.007
Identities = 31/150 (20%), Positives = 60/150 (40%), Gaps = 10/150 (6%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D + ++T D +++ +T Q + GHT + PD + I+ + D + ++W+
Sbjct: 153 DDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWD 212
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQH----W-AFSDIRTGQLLTKVSDF 340
V H+ + + +L D W + R G L +
Sbjct: 213 VREGTCRQTFTGHESDINAICFFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDNRV 272
Query: 341 SGVSLTTAQFHPDGLIFGTGTENSQVKIWD 370
S + +T DG+ TG+ +S +KIW+
Sbjct: 273 SCLGVTA-----DGMAVATGSWDSFLKIWN 297
>BC012075-1|AAH12075.1| 485|Homo sapiens notchless homolog 1
(Drosophila) protein.
Length = 485
Score = 67.7 bits (158), Expect = 9e-11
Identities = 41/175 (23%), Positives = 79/175 (45%), Gaps = 4/175 (2%)
Query: 239 ATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILR-- 296
A+V +D + + LK ++ + +++ S D T+ +W+ P + R
Sbjct: 311 ASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWS-PAEDKKPLTRMT 369
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLI 356
H + + P V S S D+ D RTG+ L + A + D +
Sbjct: 370 GHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIA-WSADSRL 428
Query: 357 FGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
+G+ +S +K+WD+K Q + PGH V ++ +S +G +A+ +D C+++W
Sbjct: 429 LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 60.9 bits (141), Expect = 1e-08
Identities = 72/308 (23%), Positives = 127/308 (41%), Gaps = 16/308 (5%)
Query: 196 QIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKG 255
++RA S HS +V +S+ +P+ L +G D ++ TE KG
Sbjct: 99 RVRAVTRCTSSLEGHSEAV---ISVAFSPTG-KYLASGSGDTTVRFWDLSTETPHFTCKG 154
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT-SQTTAILRSHDGPVTGLS---LH--P 309
H V + + PD + + + I +W+ T Q L H +TGLS LH P
Sbjct: 155 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANP 214
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
YV S+S D D G+ ++ S+T ++ DGL++ + +++ +K+W
Sbjct: 215 ECRYVASSSKDGSVRIWDTTAGR-CERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVW 272
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+ GH V +++ S + Y L T A + + + L+ E +
Sbjct: 273 RAHDGVLCRTLQGHGHWVNTMALSTD-YALRTGAFEPAEASVNPQDLQGSLQELKERALS 331
Query: 430 IKELCFDQSGTYLAIAGTDVRVYLCRQWQELKV---FNDHTASATGVRFGKNAQYLASTS 486
L Q L D ++L ++ K H A V F +++ +AS S
Sbjct: 332 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 391
Query: 487 MDRTLKLY 494
D+++KL+
Sbjct: 392 FDKSIKLW 399
Score = 60.5 bits (140), Expect = 1e-08
Identities = 65/294 (22%), Positives = 126/294 (42%), Gaps = 17/294 (5%)
Query: 210 HSASVPGIL--SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP 267
HS + G+ L NP + + + D + +++ + IL GHT+ VT + +
Sbjct: 198 HSKWITGLSWEPLHANP-ECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGG 256
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS- 326
D + +AS D TI+VW L+ H V ++L + DY L T + + S
Sbjct: 257 D-GLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMAL--STDYALRTGAFEPAEASV 313
Query: 327 ---DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN-VANFPG 382
D++ K S +L Q P+ L+ +G+++ + +W E + G
Sbjct: 314 NPQDLQGSLQELKERALSRYNLVRGQ-GPERLV--SGSDDFTLFLWSPAEDKKPLTRMTG 370
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H + + FS + +A+A+ D +KLWD R K +++ A+ ++ + L
Sbjct: 371 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLR-GHVAAVYQIAWSADSRLL 429
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+D ++V+ + + H V + + Q +AS D+ L+++
Sbjct: 430 VSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 51.2 bits (117), Expect = 8e-06
Identities = 60/289 (20%), Positives = 119/289 (41%), Gaps = 11/289 (3%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIY-----HPDED 270
+LS+ +P D KL +G + +++ T +QV L GH+K +T + + +P+
Sbjct: 159 VLSISWSP-DGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECR 217
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
V ++S D ++R+W+ + IL H VT L G + S S D+
Sbjct: 218 YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 276
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G +L + G + T D + E ++ + Q ++ ++
Sbjct: 277 G-VLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNL 335
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-- 448
+ L + ++D + LW + K T I ++ F +A A D
Sbjct: 336 VRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKS 395
Query: 449 VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++++ R + L H A+ + + +++ L S S D TLK++ ++
Sbjct: 396 IKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 444
>BC002884-1|AAH02884.2| 484|Homo sapiens NLE1 protein protein.
Length = 484
Score = 67.7 bits (158), Expect = 9e-11
Identities = 41/175 (23%), Positives = 79/175 (45%), Gaps = 4/175 (2%)
Query: 239 ATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILR-- 296
A+V +D + + LK ++ + +++ S D T+ +W+ P + R
Sbjct: 310 ASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWS-PAEDKKPLTRMT 368
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLI 356
H + + P V S S D+ D RTG+ L + A + D +
Sbjct: 369 GHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIA-WSADSRL 427
Query: 357 FGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
+G+ +S +K+WD+K Q + PGH V ++ +S +G +A+ +D C+++W
Sbjct: 428 LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482
Score = 60.9 bits (141), Expect = 1e-08
Identities = 72/308 (23%), Positives = 127/308 (41%), Gaps = 16/308 (5%)
Query: 196 QIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKG 255
++RA S HS +V +S+ +P+ L +G D ++ TE KG
Sbjct: 98 RVRAVTRCTSSLEGHSEAV---ISVAFSPTG-KYLASGSGDTTVRFWDLSTETPHFTCKG 153
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT-SQTTAILRSHDGPVTGLS---LH--P 309
H V + + PD + + + I +W+ T Q L H +TGLS LH P
Sbjct: 154 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANP 213
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
YV S+S D D G+ ++ S+T ++ DGL++ + +++ +K+W
Sbjct: 214 ECRYVASSSKDGSVRIWDTTAGR-CERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVW 271
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+ GH V +++ S + Y L T A + + + L+ E +
Sbjct: 272 RAHDGVLCRTLQGHGHWVNTMALSTD-YALRTGAFEPAEASVNPQDLQGSLQELKERALS 330
Query: 430 IKELCFDQSGTYLAIAGTDVRVYLCRQWQELKV---FNDHTASATGVRFGKNAQYLASTS 486
L Q L D ++L ++ K H A V F +++ +AS S
Sbjct: 331 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 390
Query: 487 MDRTLKLY 494
D+++KL+
Sbjct: 391 FDKSIKLW 398
Score = 60.5 bits (140), Expect = 1e-08
Identities = 65/294 (22%), Positives = 126/294 (42%), Gaps = 17/294 (5%)
Query: 210 HSASVPGIL--SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP 267
HS + G+ L NP + + + D + +++ + IL GHT+ VT + +
Sbjct: 197 HSKWITGLSWEPLHANP-ECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGG 255
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS- 326
D + +AS D TI+VW L+ H V ++L + DY L T + + S
Sbjct: 256 D-GLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMAL--STDYALRTGAFEPAEASV 312
Query: 327 ---DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN-VANFPG 382
D++ K S +L Q P+ L+ +G+++ + +W E + G
Sbjct: 313 NPQDLQGSLQELKERALSRYNLVRGQ-GPERLV--SGSDDFTLFLWSPAEDKKPLTRMTG 369
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H + + FS + +A+A+ D +KLWD R K +++ A+ ++ + L
Sbjct: 370 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLR-GHVAAVYQIAWSADSRLL 428
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+D ++V+ + + H V + + Q +AS D+ L+++
Sbjct: 429 VSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482
Score = 51.2 bits (117), Expect = 8e-06
Identities = 60/289 (20%), Positives = 119/289 (41%), Gaps = 11/289 (3%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIY-----HPDED 270
+LS+ +P D KL +G + +++ T +QV L GH+K +T + + +P+
Sbjct: 158 VLSISWSP-DGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECR 216
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
V ++S D ++R+W+ + IL H VT L G + S S D+
Sbjct: 217 YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 275
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G +L + G + T D + E ++ + Q ++ ++
Sbjct: 276 G-VLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNL 334
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-- 448
+ L + ++D + LW + K T I ++ F +A A D
Sbjct: 335 VRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKS 394
Query: 449 VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++++ R + L H A+ + + +++ L S S D TLK++ ++
Sbjct: 395 IKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 443
>AY336089-1|AAR24619.1| 271|Homo sapiens proliferation-inducing
gene 21 protein.
Length = 271
Score = 67.7 bits (158), Expect = 9e-11
Identities = 46/162 (28%), Positives = 77/162 (47%), Gaps = 6/162 (3%)
Query: 255 GHTKKVTRVIYHPDEDTVITASPDHTIRVWN-VPTSQTTAILRSHDGPVTGLSLHP--TG 311
GHTK V V + D +++ S D TI++WN + + T SH V+ + P +
Sbjct: 57 GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSN 116
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDL 371
++S D+ ++ +L T +G L T PDG + +G ++ Q +WDL
Sbjct: 117 PIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY-LNTVTVSPDGSLCASGGKDGQAMLWDL 175
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDL 413
E ++ G + ++ FS N Y+L A S +K+WDL
Sbjct: 176 NEGKHLYTLDGG-DIINALCFSPNRYWLCAATGPS-IKIWDL 215
Score = 46.8 bits (106), Expect = 2e-04
Identities = 26/88 (29%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 366 VKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLE 425
VK+W+L N GH G + +++ S +G A+ +D LWDL + K+ T L+
Sbjct: 128 VKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYT--LD 185
Query: 426 ENYAIKELCFDQSGTYL-AIAGTDVRVY 452
I LCF + +L A G ++++
Sbjct: 186 GGDIINALCFSPNRYWLCAATGPSIKIW 213
Score = 45.2 bits (102), Expect = 5e-04
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 15/201 (7%)
Query: 225 SDHSKLLTGGNDRNATVFNK-DTEQVVAILKGHTKKVTRVIYHPDEDT--VITASPDHTI 281
SD+ ++++G D+ ++N + + H++ V+ V + P+ +++ D +
Sbjct: 69 SDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLV 128
Query: 282 RVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFS 341
+VWN+ + H G + +++ P G S D D+ G+ L +
Sbjct: 129 KVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLD--G 186
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQ-------SNVANFPGHVGP--VTSISF 392
G + F P+ T S +KIWDL+ + V + P TS+++
Sbjct: 187 GDIINALCFSPNRYWLCAATGPS-IKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAW 245
Query: 393 SENGYYLATAAEDSCVKLWDL 413
S +G L D+ V++W +
Sbjct: 246 SADGQTLFAGYTDNLVRVWQV 266
Score = 31.5 bits (68), Expect = 7.1
Identities = 11/41 (26%), Positives = 22/41 (53%)
Query: 372 KEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
++ + F GH V S++FS + + + + D +KLW+
Sbjct: 47 RKGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 87
>AK222576-1|BAD96296.1| 421|Homo sapiens WD SOCS-box protein 1
isoform 1 variant protein.
Length = 421
Score = 67.7 bits (158), Expect = 9e-11
Identities = 58/243 (23%), Positives = 104/243 (42%), Gaps = 21/243 (8%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTV-ITASPDHTIRVW 284
D L TG N+ +++ T +++ L HT+ V + + PD + ++AS D T+RVW
Sbjct: 139 DQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVW 198
Query: 285 NV-PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGV 343
++ +LR H V + P + S + + ++ ++ K+ +
Sbjct: 199 DLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL-EGRHH 257
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGP--------------VTS 389
+ F PDG + T + +++V IWD + F GH+ P V S
Sbjct: 258 DVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEF-GHLFPPPTPIFAGGANDRWVRS 316
Query: 390 ISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDV 449
+SFS +G ++A+ A+D V+ W + + + L F G+ LA D
Sbjct: 317 VSFSHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLC---CAFSTDGSVLAAGTHDG 373
Query: 450 RVY 452
VY
Sbjct: 374 SVY 376
Score = 54.4 bits (125), Expect = 9e-07
Identities = 38/152 (25%), Positives = 68/152 (44%), Gaps = 1/152 (0%)
Query: 262 RVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL-STSSD 320
R + D+ + T + I++W+V T + L H V L+ P G +L S S D
Sbjct: 133 RFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRD 192
Query: 321 QHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANF 380
+ D++ + KV + + F PD + + + V +W++ + + +
Sbjct: 193 KTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKL 252
Query: 381 PGHVGPVTSISFSENGYYLATAAEDSCVKLWD 412
G V + FS +G LATA+ D+ V +WD
Sbjct: 253 EGRHHDVVACDFSPDGALLATASYDTRVYIWD 284
Score = 53.2 bits (122), Expect = 2e-06
Identities = 34/150 (22%), Positives = 66/150 (44%), Gaps = 5/150 (3%)
Query: 349 QFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENG-YYLATAAEDSC 407
+F D L+ TG N ++KIWD+ + N H V ++F+ +G L +A+ D
Sbjct: 135 RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKT 194
Query: 408 VKLWDLRKLKN-FKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCR--QWQELKVFN 464
+++WDL+ N K ++ +N+ + F + L G V+L ++ ++
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNW-VYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLE 253
Query: 465 DHTASATGVRFGKNAQYLASTSMDRTLKLY 494
F + LA+ S D + ++
Sbjct: 254 GRHHDVVACDFSPDGALLATASYDTRVYIW 283
Score = 50.0 bits (114), Expect = 2e-05
Identities = 44/211 (20%), Positives = 80/211 (37%), Gaps = 21/211 (9%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFN-KDTEQVVAILKGHTKKVTRVIYHPDEDTVITA 275
+ L P L++ D+ V++ KD ++ +L+GH V + PD + +
Sbjct: 173 VRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSV 232
Query: 276 SPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLT 335
+ +WN+ L V P G + + S D D G +L
Sbjct: 233 GASKAVFLWNMDKYTMIRKLEGRHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILM 292
Query: 336 KVSD--------FSGVS----LTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGH 383
+ F+G + + + F DGL + ++ V+ W + E ++P
Sbjct: 293 EFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFWRIDE-----DYPVQ 347
Query: 384 VGPVTS---ISFSENGYYLATAAEDSCVKLW 411
V P+++ +FS +G LA D V W
Sbjct: 348 VAPLSNGLCCAFSTDGSVLAAGTHDGSVYFW 378
>AK001320-1|BAA91621.1| 485|Homo sapiens protein ( Homo sapiens
cDNA FLJ10458 fis, clone NT2RP1001457, highly similar to
Homo sapiens partial mRNA for beta-transducin family
protein. ).
Length = 485
Score = 67.7 bits (158), Expect = 9e-11
Identities = 41/175 (23%), Positives = 79/175 (45%), Gaps = 4/175 (2%)
Query: 239 ATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILR-- 296
A+V +D + + LK ++ + +++ S D T+ +W+ P + R
Sbjct: 311 ASVNPQDLQGSLQELKERALSRYNLVRGQGPERLVSGSDDFTLFLWS-PAEDKKPLTRMT 369
Query: 297 SHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLI 356
H + + P V S S D+ D RTG+ L + A + D +
Sbjct: 370 GHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRGHVAAVYQIA-WSADSRL 428
Query: 357 FGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLW 411
+G+ +S +K+WD+K Q + PGH V ++ +S +G +A+ +D C+++W
Sbjct: 429 LVSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 60.9 bits (141), Expect = 1e-08
Identities = 72/308 (23%), Positives = 127/308 (41%), Gaps = 16/308 (5%)
Query: 196 QIRAFLTLASHPGLHSASVPGILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKG 255
++RA S HS +V +S+ +P+ L +G D ++ TE KG
Sbjct: 99 RVRAVTRCTSSLEGHSEAV---ISVAFSPTG-KYLASGSGDTTVRFWDLSTETPHFTCKG 154
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPT-SQTTAILRSHDGPVTGLS---LH--P 309
H V + + PD + + + I +W+ T Q L H +TGLS LH P
Sbjct: 155 HRHWVLSISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANP 214
Query: 310 TGDYVLSTSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIW 369
YV S+S D D G+ ++ S+T ++ DGL++ + +++ +K+W
Sbjct: 215 ECRYVASSSKDGSVRIWDTTAGR-CERILTGHTQSVTCLRWGGDGLLY-SASQDRTIKVW 272
Query: 370 DLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYA 429
+ GH V +++ S + Y L T A + + + L+ E +
Sbjct: 273 RAHDGVLCRTLQGHGHWVNTMALSTD-YALRTGAFEPAEASVNPQDLQGSLQELKERALS 331
Query: 430 IKELCFDQSGTYLAIAGTDVRVYLCRQWQELKV---FNDHTASATGVRFGKNAQYLASTS 486
L Q L D ++L ++ K H A V F +++ +AS S
Sbjct: 332 RYNLVRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASAS 391
Query: 487 MDRTLKLY 494
D+++KL+
Sbjct: 392 FDKSIKLW 399
Score = 60.5 bits (140), Expect = 1e-08
Identities = 65/294 (22%), Positives = 126/294 (42%), Gaps = 17/294 (5%)
Query: 210 HSASVPGIL--SLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHP 267
HS + G+ L NP + + + D + +++ + IL GHT+ VT + +
Sbjct: 198 HSKWITGLSWEPLHANP-ECRYVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGG 256
Query: 268 DEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFS- 326
D + +AS D TI+VW L+ H V ++L + DY L T + + S
Sbjct: 257 D-GLLYSASQDRTIKVWRAHDGVLCRTLQGHGHWVNTMAL--STDYALRTGAFEPAEASV 313
Query: 327 ---DIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSN-VANFPG 382
D++ K S +L Q P+ L+ +G+++ + +W E + G
Sbjct: 314 NPQDLQGSLQELKERALSRYNLVRGQ-GPERLV--SGSDDFTLFLWSPAEDKKPLTRMTG 370
Query: 383 HVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYL 442
H + + FS + +A+A+ D +KLWD R K +++ A+ ++ + L
Sbjct: 371 HQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLR-GHVAAVYQIAWSADSRLL 429
Query: 443 AIAGTD--VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLY 494
+D ++V+ + + H V + + Q +AS D+ L+++
Sbjct: 430 VSGSSDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483
Score = 51.2 bits (117), Expect = 8e-06
Identities = 60/289 (20%), Positives = 119/289 (41%), Gaps = 11/289 (3%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDT-EQVVAILKGHTKKVTRVIY-----HPDED 270
+LS+ +P D KL +G + +++ T +QV L GH+K +T + + +P+
Sbjct: 159 VLSISWSP-DGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECR 217
Query: 271 TVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRT 330
V ++S D ++R+W+ + IL H VT L G + S S D+
Sbjct: 218 YVASSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHD 276
Query: 331 GQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
G +L + G + T D + E ++ + Q ++ ++
Sbjct: 277 G-VLCRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQGSLQELKERALSRYNL 335
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTD-- 448
+ L + ++D + LW + K T I ++ F +A A D
Sbjct: 336 VRGQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKS 395
Query: 449 VRVYLCRQWQELKVFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
++++ R + L H A+ + + +++ L S S D TLK++ ++
Sbjct: 396 IKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVK 444
>AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 67.7 bits (158), Expect = 9e-11
Identities = 55/261 (21%), Positives = 110/261 (42%), Gaps = 22/261 (8%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
+++ HT V + D + + D T++V+ T + +++H+ V +
Sbjct: 610 VVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDD 669
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG----VSLTTAQFHPDGLIFGTGTENSQVK 367
++ + S D+ + TG+L+ + S T + H L+ TG+ + +K
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHH---LLLATGSSDCFLK 726
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL--- 424
+WDL ++ GH V FS + LA+ + D +KLWD K+I +
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 425 --------EENYAIKELC-FDQSGTYLAIAGTDVRVYLCRQWQELKVFN--DHTASATGV 473
E+ I + C + G + +A + +++L KV + H + GV
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGV 845
Query: 474 RFGKNAQYLASTSMDRTLKLY 494
F + ++S D+T++L+
Sbjct: 846 MFSPDGSSFLTSSDDQTIRLW 866
Score = 56.8 bits (131), Expect = 2e-07
Identities = 55/198 (27%), Positives = 82/198 (41%), Gaps = 10/198 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H K V R+ + DE T+I++S D I+VWN + LR H V L +L
Sbjct: 959 HKKTVWRIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQETVKDFRLLKN-PRLL 1016
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
S S D +I TG G L+ H D F + + + KIW
Sbjct: 1017 SWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISH-DATKFSSTSADKTAKIWSFDLLL 1075
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLEENYA---- 429
+ GH G V +FS + LAT ++ +++W++ +L + EE A
Sbjct: 1076 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGG 1135
Query: 430 -IKELCFDQSGTYLAIAG 446
+ +LCF G L AG
Sbjct: 1136 WVTDLCFSPDGKMLISAG 1153
Score = 54.4 bits (125), Expect = 9e-07
Identities = 61/276 (22%), Positives = 118/276 (42%), Gaps = 14/276 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D ++++ ++ ++N D+ VA +GH V V++ PD + +T+S D TIR+W
Sbjct: 808 ADGARIMVAAKNK-IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 866
Query: 285 NV-PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQL--LTKVSDFS 341
+ +A++ + V VL+ + + RTGQ+ LT+
Sbjct: 867 ETKKVCKNSAVMLKQEVDVV---FQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQ--- 920
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
VS H + F G EN ++I +L + H V I F+ + L +
Sbjct: 921 -VSCCCLSPHLQYIAF--GDENGAIEILELVNNRIFQSRFQHKKTVWRIQFTADEKTLIS 977
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
+++D+ +++W+ + K +E L + + GT V+V+ + K
Sbjct: 978 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNPRLLSWSFDGT-VKVWNIITGNKEK 1036
Query: 462 VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
F H + +A +STS D+T K++ +
Sbjct: 1037 DFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 47.6 bits (108), Expect = 1e-04
Identities = 30/147 (20%), Positives = 62/147 (42%), Gaps = 3/147 (2%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++ + G D+ VF +T + + +K H +V + D+ + T S D +++WN
Sbjct: 626 DGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN 685
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVL--STSSDQHWAFSDIRTGQLLTKVSDFSGV 343
T + H V + ++L + SSD D+ + + +
Sbjct: 686 SMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTN- 744
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWD 370
S+ +F PD + + + + +K+WD
Sbjct: 745 SVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 38.7 bits (86), Expect = 0.047
Identities = 17/67 (25%), Positives = 35/67 (52%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
N S H L TG +D +++ + ++ + GHT V + PD+ + + S D T++
Sbjct: 709 NSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLK 768
Query: 283 VWNVPTS 289
+W+ ++
Sbjct: 769 LWDATSA 775
Score = 38.3 bits (85), Expect = 0.062
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 9/115 (7%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+LS DI+ D +K + D+ A +++ D + L+GH V + D + T
Sbjct: 1045 VLSCDIS-HDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 277 PDHTIRVWNVPTSQTTAI--------LRSHDGPVTGLSLHPTGDYVLSTSSDQHW 323
+ IR+WNV + + +H G VT L P G ++S W
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKW 1158
>AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 67.7 bits (158), Expect = 9e-11
Identities = 54/261 (20%), Positives = 111/261 (42%), Gaps = 22/261 (8%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
+++ HT V + D + + D T++V+ T + +++H+ V +
Sbjct: 610 VVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDD 669
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG----VSLTTAQFHPDGLIFGTGTENSQVK 367
++ + S D+ + TG+L+ + S T + H L+ TG+ + +K
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHH---LLLATGSSDCFLK 726
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEEN 427
+WDL ++ GH V FS + LA+ + D +KLWD K+I +++
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 428 Y-----------AIKELC-FDQSGTYLAIAGTDVRVYLCRQWQELKVFN--DHTASATGV 473
+ I + C + G + +A + +++L KV + H + GV
Sbjct: 787 FLNLEDPQGDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVTDCRGHLSWVHGV 845
Query: 474 RFGKNAQYLASTSMDRTLKLY 494
F + ++S D+T++L+
Sbjct: 846 MFSPDGSSFLTSSDDQTIRLW 866
Score = 55.2 bits (127), Expect = 5e-07
Identities = 54/198 (27%), Positives = 81/198 (40%), Gaps = 10/198 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H K V + + DE T+I++S D I+VWN + LR H V L +L
Sbjct: 959 HKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDK-CIFLRGHQETVKDFRL-LKNSRLL 1016
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
S S D +I TG G L+ H D F + + + KIW
Sbjct: 1017 SWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISH-DATKFSSTSADKTAKIWSFDLLL 1075
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLEENYA---- 429
+ GH G V +FS + LAT ++ +++W++ +L + EE A
Sbjct: 1076 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGG 1135
Query: 430 -IKELCFDQSGTYLAIAG 446
+ +LCF G L AG
Sbjct: 1136 WVTDLCFSPDGKMLISAG 1153
Score = 53.2 bits (122), Expect = 2e-06
Identities = 60/276 (21%), Positives = 117/276 (42%), Gaps = 14/276 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D ++++ ++ ++N D+ V +GH V V++ PD + +T+S D TIR+W
Sbjct: 808 ADGARIMVAAKNK-IFLWNTDSRSKVTDCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 866
Query: 285 NVP-TSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQL--LTKVSDFS 341
+ +A++ + V VL+ + + RTGQ+ LT+
Sbjct: 867 ETKKVCKNSAVMLKQEVDVV---FQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQ--- 920
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
VS H + FG EN ++I +L + H V I F+ + L +
Sbjct: 921 -VSCCCLSPHLQYIAFGD--ENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
+++D+ +++W+ + K +E L + + GT V+V+ + K
Sbjct: 978 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGT-VKVWNIITGNKEK 1036
Query: 462 VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
F H + +A +STS D+T K++ +
Sbjct: 1037 DFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 51.6 bits (118), Expect = 6e-06
Identities = 42/216 (19%), Positives = 90/216 (41%), Gaps = 15/216 (6%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVI--TASPDHTIR 282
+D + T D+ ++N T ++V H+++V + ++ T S D ++
Sbjct: 667 TDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLK 726
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSD---QHWAFSD------IRTGQL 333
+W++ + + H V P + S S+D + W + I Q
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 334 LTKVSDFSG---VSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSI 390
+ D G V + + DG +N ++ +W+ +S V + GH+ V +
Sbjct: 787 FLNLEDPQGDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVTDCRGHLSWVHGV 845
Query: 391 SFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQLEE 426
FS +G T+++D ++LW+ +K+ + L++
Sbjct: 846 MFSPDGSSFLTSSDDQTIRLWETKKVCKNSAVMLKQ 881
Score = 47.6 bits (108), Expect = 1e-04
Identities = 30/147 (20%), Positives = 62/147 (42%), Gaps = 3/147 (2%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++ + G D+ VF +T + + +K H +V + D+ + T S D +++WN
Sbjct: 626 DGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN 685
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVL--STSSDQHWAFSDIRTGQLLTKVSDFSGV 343
T + H V + ++L + SSD D+ + + +
Sbjct: 686 SMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTN- 744
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWD 370
S+ +F PD + + + + +K+WD
Sbjct: 745 SVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 41.1 bits (92), Expect = 0.009
Identities = 40/165 (24%), Positives = 76/165 (46%), Gaps = 17/165 (10%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
N S H L TG +D +++ + ++ + GHT V + PD+ + + S D T++
Sbjct: 709 NSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLK 768
Query: 283 VWNVPTSQTTAILRSHDGPVTGLSLH-PTGDYVL-----STSSDQHWAFSDIRTGQLL-- 334
+W+ ++ +S + L+L P GD + S S+D + L
Sbjct: 769 LWDATSANER---KSINVKQFFLNLEDPQGDMEVIVKCCSWSADGARIMVAAKNKIFLWN 825
Query: 335 ----TKVSDFSG-VS-LTTAQFHPDGLIFGTGTENSQVKIWDLKE 373
+KV+D G +S + F PDG F T +++ +++W+ K+
Sbjct: 826 TDSRSKVTDCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKK 870
Score = 38.3 bits (85), Expect = 0.062
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 9/115 (7%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+LS DI+ D +K + D+ A +++ D + L+GH V + D + T
Sbjct: 1045 VLSCDIS-HDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 277 PDHTIRVWNVPTSQTTAI--------LRSHDGPVTGLSLHPTGDYVLSTSSDQHW 323
+ IR+WNV + + +H G VT L P G ++S W
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKW 1158
>AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease
activating factor 1 protein.
Length = 1205
Score = 67.7 bits (158), Expect = 9e-11
Identities = 55/261 (21%), Positives = 110/261 (42%), Gaps = 22/261 (8%)
Query: 252 ILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTG 311
+++ HT V + D + + D T++V+ T + +++H+ V +
Sbjct: 610 VVRPHTDAVYHACFSEDGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDD 669
Query: 312 DYVLSTSSDQHWAFSDIRTGQLLTKVSDFSG----VSLTTAQFHPDGLIFGTGTENSQVK 367
++ + S D+ + TG+L+ + S T + H L+ TG+ + +K
Sbjct: 670 RFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHH---LLLATGSSDCFLK 726
Query: 368 IWDLKEQSNVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLRKLKNFKTIQL--- 424
+WDL ++ GH V FS + LA+ + D +KLWD K+I +
Sbjct: 727 LWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKSINVKQF 786
Query: 425 --------EENYAIKELC-FDQSGTYLAIAGTDVRVYLCRQWQELKVFN--DHTASATGV 473
E+ I + C + G + +A + +++L KV + H + GV
Sbjct: 787 FLNLEDPQEDMEVIVKCCSWSADGARIMVAAKN-KIFLWNTDSRSKVADCRGHLSWVHGV 845
Query: 474 RFGKNAQYLASTSMDRTLKLY 494
F + ++S D+T++L+
Sbjct: 846 MFSPDGSSFLTSSDDQTIRLW 866
Score = 55.2 bits (127), Expect = 5e-07
Identities = 54/198 (27%), Positives = 81/198 (40%), Gaps = 10/198 (5%)
Query: 256 HTKKVTRVIYHPDEDTVITASPDHTIRVWNVPTSQTTAILRSHDGPVTGLSLHPTGDYVL 315
H K V + + DE T+I++S D I+VWN + LR H V L +L
Sbjct: 959 HKKTVWHIQFTADEKTLISSSDDAEIQVWNWQLDKCI-FLRGHQETVKDFRLLKNSR-LL 1016
Query: 316 STSSDQHWAFSDIRTGQLLTKVSDFSGVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQS 375
S S D +I TG G L+ H D F + + + KIW
Sbjct: 1017 SWSFDGTVKVWNIITGNKEKDFVCHQGTVLSCDISH-DATKFSSTSADKTAKIWSFDLLL 1075
Query: 376 NVANFPGHVGPVTSISFSENGYYLATAAEDSCVKLWDLR--KLKNFKTIQLEENYA---- 429
+ GH G V +FS + LAT ++ +++W++ +L + EE A
Sbjct: 1076 PLHELRGHNGCVRCSAFSVDSTLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGG 1135
Query: 430 -IKELCFDQSGTYLAIAG 446
+ +LCF G L AG
Sbjct: 1136 WVTDLCFSPDGKMLISAG 1153
Score = 54.8 bits (126), Expect = 7e-07
Identities = 61/276 (22%), Positives = 118/276 (42%), Gaps = 14/276 (5%)
Query: 225 SDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVW 284
+D ++++ ++ ++N D+ VA +GH V V++ PD + +T+S D TIR+W
Sbjct: 808 ADGARIMVAAKNK-IFLWNTDSRSKVADCRGHLSWVHGVMFSPDGSSFLTSSDDQTIRLW 866
Query: 285 NV-PTSQTTAILRSHDGPVTGLSLHPTGDYVLSTSSDQHWAFSDIRTGQL--LTKVSDFS 341
+ +A++ + V VL+ + + RTGQ+ LT+
Sbjct: 867 ETKKVCKNSAVMLKQEVDVV---FQENEVMVLAVDHIRRLQLINGRTGQIDYLTEAQ--- 920
Query: 342 GVSLTTAQFHPDGLIFGTGTENSQVKIWDLKEQSNVANFPGHVGPVTSISFSENGYYLAT 401
VS H + F G EN ++I +L + H V I F+ + L +
Sbjct: 921 -VSCCCLSPHLQYIAF--GDENGAIEILELVNNRIFQSRFQHKKTVWHIQFTADEKTLIS 977
Query: 402 AAEDSCVKLWDLRKLKNFKTIQLEENYAIKELCFDQSGTYLAIAGTDVRVYLCRQWQELK 461
+++D+ +++W+ + K +E L + + GT V+V+ + K
Sbjct: 978 SSDDAEIQVWNWQLDKCIFLRGHQETVKDFRLLKNSRLLSWSFDGT-VKVWNIITGNKEK 1036
Query: 462 VFNDHTASATGVRFGKNAQYLASTSMDRTLKLYGIE 497
F H + +A +STS D+T K++ +
Sbjct: 1037 DFVCHQGTVLSCDISHDATKFSSTSADKTAKIWSFD 1072
Score = 47.6 bits (108), Expect = 1e-04
Identities = 30/147 (20%), Positives = 62/147 (42%), Gaps = 3/147 (2%)
Query: 226 DHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIRVWN 285
D ++ + G D+ VF +T + + +K H +V + D+ + T S D +++WN
Sbjct: 626 DGQRIASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN 685
Query: 286 VPTSQTTAILRSHDGPVTGLSLHPTGDYVL--STSSDQHWAFSDIRTGQLLTKVSDFSGV 343
T + H V + ++L + SSD D+ + + +
Sbjct: 686 SMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTN- 744
Query: 344 SLTTAQFHPDGLIFGTGTENSQVKIWD 370
S+ +F PD + + + + +K+WD
Sbjct: 745 SVNHCRFSPDDKLLASCSADGTLKLWD 771
Score = 38.7 bits (86), Expect = 0.047
Identities = 17/67 (25%), Positives = 35/67 (52%)
Query: 223 NPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITASPDHTIR 282
N S H L TG +D +++ + ++ + GHT V + PD+ + + S D T++
Sbjct: 709 NSSHHLLLATGSSDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLK 768
Query: 283 VWNVPTS 289
+W+ ++
Sbjct: 769 LWDATSA 775
Score = 38.3 bits (85), Expect = 0.062
Identities = 29/115 (25%), Positives = 48/115 (41%), Gaps = 9/115 (7%)
Query: 217 ILSLDINPSDHSKLLTGGNDRNATVFNKDTEQVVAILKGHTKKVTRVIYHPDEDTVITAS 276
+LS DI+ D +K + D+ A +++ D + L+GH V + D + T
Sbjct: 1045 VLSCDIS-HDATKFSSTSADKTAKIWSFDLLLPLHELRGHNGCVRCSAFSVDSTLLATGD 1103
Query: 277 PDHTIRVWNVPTSQTTAI--------LRSHDGPVTGLSLHPTGDYVLSTSSDQHW 323
+ IR+WNV + + +H G VT L P G ++S W
Sbjct: 1104 DNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAGGYIKW 1158
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.316 0.131 0.380
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 66,748,722
Number of Sequences: 224733
Number of extensions: 2676517
Number of successful extensions: 15536
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 821
Number of HSP's successfully gapped in prelim test: 342
Number of HSP's that attempted gapping in prelim test: 6868
Number of HSP's gapped (non-prelim): 5021
length of query: 497
length of database: 73,234,838
effective HSP length: 93
effective length of query: 404
effective length of database: 52,334,669
effective search space: 21143206276
effective search space used: 21143206276
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 67 (31.1 bits)
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