Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002827-TA|BGIBMGA002827-PA|IPR002347|Glucose/ribitol
dehydrogenase
(276 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 106 7e-23
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 106 7e-23
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 106 7e-23
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 106 7e-23
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 106 7e-23
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 106 7e-23
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 106 7e-23
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 106 7e-23
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 106 7e-23
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 106 7e-23
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 106 7e-23
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 104 3e-22
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 104 3e-22
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 104 3e-22
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 104 3e-22
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 104 3e-22
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 104 3e-22
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 104 3e-22
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 104 3e-22
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 104 3e-22
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 104 4e-22
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 47 6e-05
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 46 1e-04
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 46 1e-04
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 46 1e-04
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 46 2e-04
AY046280-1|AAK91586.1| 132|Homo sapiens hydroxysteroid dehydrog... 39 0.017
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 37 0.088
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 37 0.088
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.088
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.088
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.088
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 37 0.088
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 36 0.12
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 36 0.15
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 36 0.15
AL023881-2|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 36 0.15
AL023881-1|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 36 0.15
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 36 0.15
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 36 0.15
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 35 0.27
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 33 0.82
BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta... 31 4.4
BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta... 31 4.4
BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta... 31 4.4
AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein. 31 4.4
AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta... 31 4.4
AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta... 31 4.4
AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta... 31 4.4
AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens ... 31 4.4
AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid d... 31 4.4
AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protei... 31 4.4
AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid ... 31 4.4
U13695-1|AAA63922.1| 932|Homo sapiens hPMS1 protein. 31 5.8
BC096332-1|AAH96332.1| 920|Homo sapiens PMS1 protein protein. 31 5.8
BC096330-1|AAH96330.1| 920|Homo sapiens PMS1 protein protein. 31 5.8
AY267352-1|AAO89079.1| 932|Homo sapiens PMS1 postmeiotic segreg... 31 5.8
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 31 5.8
AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid d... 31 5.8
AB102875-1|BAD89404.1| 893|Homo sapiens PMS1 nirs variant 7 pro... 31 5.8
AB102872-1|BAD89401.1| 555|Homo sapiens PMS1 nirs variant 4 pro... 31 5.8
AB102870-1|BAD89399.1| 770|Homo sapiens PMS1 nirs variant 2 pro... 31 5.8
BC063300-1|AAH63300.1| 641|Homo sapiens mannosidase, alpha, cla... 30 7.7
AL358072-2|CAH71080.1| 343|Homo sapiens mannosidase, alpha, cla... 30 7.7
AL358072-1|CAH71079.1| 641|Homo sapiens mannosidase, alpha, cla... 30 7.7
AL157902-4|CAI22318.1| 343|Homo sapiens mannosidase, alpha, cla... 30 7.7
AL157902-1|CAI22315.1| 641|Homo sapiens mannosidase, alpha, cla... 30 7.7
AK023308-1|BAB14518.1| 618|Homo sapiens protein ( Homo sapiens ... 30 7.7
AF027156-1|AAC26169.1| 641|Homo sapiens alpha 1,2-mannosidase I... 30 7.7
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 106 bits (255), Expect = 7e-23
Identities = 72/255 (28%), Positives = 132/255 (51%), Gaps = 10/255 (3%)
Query: 3 NVALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDIT 62
+VALV G +G +++ L G + T D T G ++ L+ + + Q+DI
Sbjct: 6 HVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDID 65
Query: 63 YTKSIIRLRHYIQDLDERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKL 119
+SI LR +++ +D+L+N I VA+ + + T+ NF+G +
Sbjct: 66 DLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTE 124
Query: 120 VYPLLNENARVVNVSGPAGLLATIE-NEDIRKRISDPTLTEDELVALIQEYEHAARRGVE 178
+ PL+ RVVNVS + A + +++++ T+TE+ELV L+ ++ ++GV
Sbjct: 125 LLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVH 184
Query: 179 KTEGWGMNVHAVSKVALNAVTFLQHREWAD--KG--IIINCVNPGSL-SGRDGRRTTKIY 233
+ EGW + + V+K+ + ++ + R+ ++ KG I++N PG + + G + TK
Sbjct: 185 QKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSP 244
Query: 234 EEGAKAILYLALEAP 248
EEGA+ +YLAL P
Sbjct: 245 EEGAETPVYLALLPP 259
>EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NADPH)
3, EC 1.1.1.284. protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbonyl
reductase 3 protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 104 bits (250), Expect = 3e-22
Identities = 72/254 (28%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K I++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVE 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3
variant protein.
Length = 277
Score = 104 bits (249), Expect = 4e-22
Identities = 71/254 (27%), Positives = 128/254 (50%), Gaps = 10/254 (3%)
Query: 4 VALVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITY 63
VALV GA +G + ++L G + T D G ++ L+ + + Q+DI
Sbjct: 7 VALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 64 TKSIIRLRHYIQDLDERIDLLIN--ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVY 121
+SI LR +++ +++L+N + ++ + K TL NF+ N +
Sbjct: 67 LQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELL 126
Query: 122 PLLNENARVVNVSGPAGLLATIEN--EDIRKRISDPTLTEDELVALIQEYEHAARRGVEK 179
P++ + RVVN+S L A EN ED+++R TLTE +LV L++++ + V +
Sbjct: 127 PIMKPHGRVVNISSLQCLRA-FENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHE 185
Query: 180 TEGWGMNVHAVSKVALNAVTFLQHREWADK----GIIINCVNPGSL-SGRDGRRTTKIYE 234
EGW + + VSK+ + ++ + R +K +++N PG + + DG+ + + E
Sbjct: 186 REGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRVLVNACCPGPVKTDMDGKDSIRTME 245
Query: 235 EGAKAILYLALEAP 248
EGA+ +YLAL P
Sbjct: 246 EGAETPVYLALLPP 259
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 47.2 bits (107), Expect = 6e-05
Identities = 41/139 (29%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
L+ G S G + KKL + E ++ G L++ P + + LQMD+T
Sbjct: 86 LITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRL--LQMDLTKPG 143
Query: 66 SIIRLRHYIQDLDERIDL--LINITDY---VAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I RL + + L L+N + VA+ LS R + VNF+G + K +
Sbjct: 144 DISRLLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGL 203
Query: 121 YPLL-NENARVVNVSGPAG 138
PLL + R+V V PAG
Sbjct: 204 LPLLRSSRGRIVTVGSPAG 222
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 46.0 bits (104), Expect = 1e-04
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
L+ G S G + KKL + E ++ G L++ P + + LQMD+T
Sbjct: 86 LITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRL--LQMDLTKPG 143
Query: 66 SIIRLRHYIQDLDERIDL--LINITDY---VAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I R+ + + L L+N + VA+ LS R + VNF+G + K +
Sbjct: 144 DISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGL 203
Query: 121 YPLL-NENARVVNVSGPAG 138
PLL + R+V V PAG
Sbjct: 204 LPLLRSSRGRIVTVGSPAG 222
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 46.0 bits (104), Expect = 1e-04
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
L+ G S G + KKL + E ++ G L++ P + + LQMD+T
Sbjct: 86 LITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRL--LQMDLTKPG 143
Query: 66 SIIRLRHYIQDLDERIDL--LINITDY---VAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I R+ + + L L+N + VA+ LS R + VNF+G + K +
Sbjct: 144 DISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGL 203
Query: 121 YPLL-NENARVVNVSGPAG 138
PLL + R+V V PAG
Sbjct: 204 LPLLRSSRGRIVTVGSPAG 222
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 46.0 bits (104), Expect = 1e-04
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
L+ G S G + KKL + E ++ G L++ P + + LQMD+T
Sbjct: 86 LITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRL--LQMDLTKPG 143
Query: 66 SIIRLRHYIQDLDERIDL--LINITDY---VAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I R+ + + L L+N + VA+ LS R + VNF+G + K +
Sbjct: 144 DISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGL 203
Query: 121 YPLL-NENARVVNVSGPAG 138
PLL + R+V V PAG
Sbjct: 204 LPLLRSSRGRIVTVGSPAG 222
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 45.6 bits (103), Expect = 2e-04
Identities = 40/139 (28%), Positives = 61/139 (43%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
L+ G S G + KKL + E ++ G L++ P + + LQMD+T
Sbjct: 86 LITGCDSGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRL--LQMDLTKPG 143
Query: 66 SIIRLRHYIQDLDERIDL--LINITDY---VAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I R + + L L+N + VA+ LS R + VNF+G + K +
Sbjct: 144 DISRFLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGL 203
Query: 121 YPLL-NENARVVNVSGPAG 138
PLL + R+V V PAG
Sbjct: 204 LPLLRSSRGRIVTVGSPAG 222
>AY046280-1|AAK91586.1| 132|Homo sapiens hydroxysteroid
dehydrogenase type 2 protein.
Length = 132
Score = 39.1 bits (87), Expect = 0.017
Identities = 37/132 (28%), Positives = 58/132 (43%), Gaps = 8/132 (6%)
Query: 12 SNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTKSIIRLR 71
S G + KKL + E ++ G L++ P + + LQMD+T I R+
Sbjct: 3 SGFGKETAKKLDSMGFTVLATVLELNSPGAIELRTCCSPRLRL--LQMDLTKPGDISRVL 60
Query: 72 HYIQDLDERIDL--LINITDY---VAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPLL-N 125
+ + L L+N + VA+ LS R + VNF+G + K + PLL +
Sbjct: 61 EFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRS 120
Query: 126 ENARVVNVSGPA 137
R+V V PA
Sbjct: 121 SRGRIVTVGSPA 132
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.088
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
LV G LG+ + K L E ++ G L+ P +S LQMDIT
Sbjct: 86 LVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP--RLSVLQMDITKPV 143
Query: 66 SIIRLRHYIQDL--DERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I + + D + +IN + + + L ++ ++VNF+G + K
Sbjct: 144 QIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTF 203
Query: 121 YPLLNEN-ARVVNVSGPAG 138
PLL ++ R+VNVS G
Sbjct: 204 LPLLRKSKGRLVNVSSMGG 222
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.088
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
LV G LG+ + K L E ++ G L+ P +S LQMDIT
Sbjct: 86 LVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP--RLSVLQMDITKPV 143
Query: 66 SIIRLRHYIQDL--DERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I + + D + +IN + + + L ++ ++VNF+G + K
Sbjct: 144 QIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTF 203
Query: 121 YPLLNEN-ARVVNVSGPAG 138
PLL ++ R+VNVS G
Sbjct: 204 LPLLRKSKGRLVNVSSMGG 222
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.088
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
LV G LG+ + K L E ++ G L+ P +S LQMDIT
Sbjct: 86 LVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP--RLSVLQMDITKPV 143
Query: 66 SIIRLRHYIQDL--DERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I + + D + +IN + + + L ++ ++VNF+G + K
Sbjct: 144 QIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTF 203
Query: 121 YPLLNEN-ARVVNVSGPAG 138
PLL ++ R+VNVS G
Sbjct: 204 LPLLRKSKGRLVNVSSMGG 222
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.088
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
LV G LG+ + K L E ++ G L+ P +S LQMDIT
Sbjct: 86 LVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP--RLSVLQMDITKPV 143
Query: 66 SIIRLRHYIQDL--DERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I + + D + +IN + + + L ++ ++VNF+G + K
Sbjct: 144 QIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTF 203
Query: 121 YPLLNEN-ARVVNVSGPAG 138
PLL ++ R+VNVS G
Sbjct: 204 LPLLRKSKGRLVNVSSMGG 222
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.088
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
LV G LG+ + K L E ++ G L+ P +S LQMDIT
Sbjct: 86 LVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP--RLSVLQMDITKPV 143
Query: 66 SIIRLRHYIQDL--DERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I + + D + +IN + + + L ++ ++VNF+G + K
Sbjct: 144 QIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTF 203
Query: 121 YPLLNEN-ARVVNVSGPAG 138
PLL ++ R+VNVS G
Sbjct: 204 LPLLRKSKGRLVNVSSMGG 222
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 36.7 bits (81), Expect = 0.088
Identities = 37/139 (26%), Positives = 59/139 (42%), Gaps = 8/139 (5%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSLERPDIEISYLQMDITYTK 65
LV G LG+ + K L E ++ G L+ P +S LQMDIT
Sbjct: 86 LVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP--RLSVLQMDITKPV 143
Query: 66 SIIRLRHYIQDL--DERIDLLIN---ITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLV 120
I + + D + +IN + + + L ++ ++VNF+G + K
Sbjct: 144 QIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTF 203
Query: 121 YPLLNEN-ARVVNVSGPAG 138
PLL ++ R+VNVS G
Sbjct: 204 LPLLRKSKGRLVNVSSMGG 222
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 36.3 bits (80), Expect = 0.12
Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 5/147 (3%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYLQMDITY 63
+V GA + +G Q +L G I D K + E + ++ +D+
Sbjct: 42 IVTGANTGIGKQTALELAR-RGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLAS 100
Query: 64 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPL 123
KSI I + +ER+D+LIN + + + + VN G+ L+
Sbjct: 101 LKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDK 160
Query: 124 LNENA--RVVNVSGPAGLLATIENEDI 148
L +A R++N+S A + I+ +D+
Sbjct: 161 LKASAPSRIINLSSLAHVAGHIDFDDL 187
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 35.9 bits (79), Expect = 0.15
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 182 GWGMNVHAVS-KVALNAVTFLQHREWADKGIIINCVNPGSLSGRDGRRTTKIYEEGAKAI 240
G + VHA S K A++A+T EW + I +N + PG +SG +G R G +A
Sbjct: 123 GQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL----GGPQAS 178
Query: 241 LYLALEA-PLSLKGNFVWSNYSVI 263
L + A PL GN +SV+
Sbjct: 179 LSTKVTASPLQRLGNKTEIAHSVL 202
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 35.9 bits (79), Expect = 0.15
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 182 GWGMNVHAVS-KVALNAVTFLQHREWADKGIIINCVNPGSLSGRDGRRTTKIYEEGAKAI 240
G + VHA S K A++A+T EW + I +N + PG +SG +G R G +A
Sbjct: 171 GQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL----GGPQAS 226
Query: 241 LYLALEA-PLSLKGNFVWSNYSVI 263
L + A PL GN +SV+
Sbjct: 227 LSTKVTASPLQRLGNKTEIAHSVL 250
>AL023881-2|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 35.9 bits (79), Expect = 0.15
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 182 GWGMNVHAVS-KVALNAVTFLQHREWADKGIIINCVNPGSLSGRDGRRTTKIYEEGAKAI 240
G + VHA S K A++A+T EW + I +N + PG +SG +G R G +A
Sbjct: 171 GQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL----GGPQAS 226
Query: 241 LYLALEA-PLSLKGNFVWSNYSVI 263
L + A PL GN +SV+
Sbjct: 227 LSTKVTASPLQRLGNKTEIAHSVL 250
>AL023881-1|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 35.9 bits (79), Expect = 0.15
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 182 GWGMNVHAVS-KVALNAVTFLQHREWADKGIIINCVNPGSLSGRDGRRTTKIYEEGAKAI 240
G + VHA S K A++A+T EW + I +N + PG +SG +G R G +A
Sbjct: 159 GQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL----GGPQAS 214
Query: 241 LYLALEA-PLSLKGNFVWSNYSVI 263
L + A PL GN +SV+
Sbjct: 215 LSTKVTASPLQRLGNKTEIAHSVL 238
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 35.9 bits (79), Expect = 0.15
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 182 GWGMNVHAVS-KVALNAVTFLQHREWADKGIIINCVNPGSLSGRDGRRTTKIYEEGAKAI 240
G + VHA S K A++A+T EW + I +N + PG +SG +G R G +A
Sbjct: 171 GQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL----GGPQAS 226
Query: 241 LYLALEA-PLSLKGNFVWSNYSVI 263
L + A PL GN +SV+
Sbjct: 227 LSTKVTASPLQRLGNKTEIAHSVL 250
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 35.9 bits (79), Expect = 0.15
Identities = 29/84 (34%), Positives = 42/84 (50%), Gaps = 6/84 (7%)
Query: 182 GWGMNVHAVS-KVALNAVTFLQHREWADKGIIINCVNPGSLSGRDGRRTTKIYEEGAKAI 240
G + VHA S K A++A+T EW + I +N + PG +SG +G R G +A
Sbjct: 171 GQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL----GGPQAS 226
Query: 241 LYLALEA-PLSLKGNFVWSNYSVI 263
L + A PL GN +SV+
Sbjct: 227 LSTKVTASPLQRLGNKTEIAHSVL 250
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 35.1 bits (77), Expect = 0.27
Identities = 34/147 (23%), Positives = 62/147 (42%), Gaps = 5/147 (3%)
Query: 6 LVVGAASNLGYQVLKKLTETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYLQMDITY 63
+V GA + +G Q +L G I D K + E + ++ +D+
Sbjct: 42 IVTGANTGIGKQTALELAR-RGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLAS 100
Query: 64 TKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGKLVYPL 123
KSI I + +ER+D+LIN + + + + VN G+ L+
Sbjct: 101 LKSIRVFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDK 160
Query: 124 LNENA--RVVNVSGPAGLLATIENEDI 148
L +A R++N+S A + I+ +D+
Sbjct: 161 LKASAPSRIINLSSLAHVAGHIDFDDL 187
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 33.5 bits (73), Expect = 0.82
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 59 MDITYTKSIIRLRHYIQDLDERIDLLINITDYVAEKNLSNFEKIRRTLSVNFYGYINFGK 118
+D+ KSI I + +ER+D+LIN + + + + VN G+
Sbjct: 25 LDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTN 84
Query: 119 LVYPLLNENA--RVVNVSGPAGLLATIENEDI 148
L+ L +A R++N+S A + I+ +D+
Sbjct: 85 LLLDKLKASAPSRIINLSSLAHVAGHIDFDDL 116
>BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 111
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens
cDNA FLJ12867 fis, clone NT2RP2003702, highly similar
to Homo sapiens 17 beta-hydroxysteroid dehydrogenase
type VII ).
Length = 155
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 7 protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protein
protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase type VII protein.
Length = 341
Score = 31.1 bits (67), Expect = 4.4
Identities = 19/87 (21%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERIDLL 84
Q+D++ +S+ R ++ +R+D +
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLDCI 87
>U13695-1|AAA63922.1| 932|Homo sapiens hPMS1 protein.
Length = 932
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 110 FYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPT-LTEDELVALIQE 168
FYG + +++ +LN NA+ V P +++ +E E +R P L+++++ +I
Sbjct: 844 FYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYR 903
Query: 169 YEH 171
+H
Sbjct: 904 MKH 906
>BC096332-1|AAH96332.1| 920|Homo sapiens PMS1 protein protein.
Length = 920
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 110 FYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPT-LTEDELVALIQE 168
FYG + +++ +LN NA+ V P +++ +E E +R P L+++++ +I
Sbjct: 844 FYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYR 903
Query: 169 YEH 171
+H
Sbjct: 904 MKH 906
>BC096330-1|AAH96330.1| 920|Homo sapiens PMS1 protein protein.
Length = 920
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 110 FYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPT-LTEDELVALIQE 168
FYG + +++ +LN NA+ V P +++ +E E +R P L+++++ +I
Sbjct: 844 FYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYR 903
Query: 169 YEH 171
+H
Sbjct: 904 MKH 906
>AY267352-1|AAO89079.1| 932|Homo sapiens PMS1 postmeiotic
segregation increased 1 (S. cerevisiae) protein.
Length = 932
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 110 FYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPT-LTEDELVALIQE 168
FYG + +++ +LN NA+ V P +++ +E E +R P L+++++ +I
Sbjct: 844 FYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYR 903
Query: 169 YEH 171
+H
Sbjct: 904 MKH 906
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/35 (45%), Positives = 21/35 (60%)
Query: 185 MNVHAVSKVALNAVTFLQHREWADKGIIINCVNPG 219
+ V++VSK AL +T E A K I +NCV PG
Sbjct: 182 LGVYSVSKTALLGLTRTLALELAPKDIRVNCVVPG 216
>AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid
dehydrogenase protein.
Length = 341
Score = 30.7 bits (66), Expect = 5.8
Identities = 19/85 (22%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
Query: 1 MCNVALVVGAASNLGYQVLKKL-TETHKGKIYFTTEDDTAGFNILKSL--ERPDIEISYL 57
M V L+ GA+S +G + K+L E + + + + + +L P E++ +
Sbjct: 1 MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV 60
Query: 58 QMDITYTKSIIRLRHYIQDLDERID 82
Q+D++ +S+ R ++ +R+D
Sbjct: 61 QVDVSNLQSVFRASKELKQRFQRLD 85
>AB102875-1|BAD89404.1| 893|Homo sapiens PMS1 nirs variant 7
protein.
Length = 893
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 110 FYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPT-LTEDELVALIQE 168
FYG + +++ +LN NA+ V P +++ +E E +R P L+++++ +I
Sbjct: 805 FYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYR 864
Query: 169 YEH 171
+H
Sbjct: 865 MKH 867
>AB102872-1|BAD89401.1| 555|Homo sapiens PMS1 nirs variant 4
protein.
Length = 555
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 110 FYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPT-LTEDELVALIQE 168
FYG + +++ +LN NA+ V P +++ +E E +R P L+++++ +I
Sbjct: 467 FYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYR 526
Query: 169 YEH 171
+H
Sbjct: 527 MKH 529
>AB102870-1|BAD89399.1| 770|Homo sapiens PMS1 nirs variant 2
protein.
Length = 770
Score = 30.7 bits (66), Expect = 5.8
Identities = 16/63 (25%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 110 FYGYINFGKLVYPLLNENARVVNVSGPAGLLATIENEDIRKRISDPT-LTEDELVALIQE 168
FYG + +++ +LN NA+ V P +++ +E E +R P L+++++ +I
Sbjct: 682 FYGVADLKEILNAILNRNAKEVYECRPRKVISYLEGEAVRLSRQLPMYLSKEDIQDIIYR 741
Query: 169 YEH 171
+H
Sbjct: 742 MKH 744
>BC063300-1|AAH63300.1| 641|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 641
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Query: 38 TAGFNILK---SLERPDIEISYLQMDITYTKSIIRLRHYIQDLD 78
+AG +IL +L I +SYL D+TY K ++ +R +Q +D
Sbjct: 327 SAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMD 370
>AL358072-2|CAH71080.1| 343|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 343
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Query: 38 TAGFNILK---SLERPDIEISYLQMDITYTKSIIRLRHYIQDLD 78
+AG +IL +L I +SYL D+TY K ++ +R +Q +D
Sbjct: 59 SAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMD 102
>AL358072-1|CAH71079.1| 641|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 641
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Query: 38 TAGFNILK---SLERPDIEISYLQMDITYTKSIIRLRHYIQDLD 78
+AG +IL +L I +SYL D+TY K ++ +R +Q +D
Sbjct: 327 SAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMD 370
>AL157902-4|CAI22318.1| 343|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 343
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Query: 38 TAGFNILK---SLERPDIEISYLQMDITYTKSIIRLRHYIQDLD 78
+AG +IL +L I +SYL D+TY K ++ +R +Q +D
Sbjct: 59 SAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMD 102
>AL157902-1|CAI22315.1| 641|Homo sapiens mannosidase, alpha, class
1A, member 2 protein.
Length = 641
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Query: 38 TAGFNILK---SLERPDIEISYLQMDITYTKSIIRLRHYIQDLD 78
+AG +IL +L I +SYL D+TY K ++ +R +Q +D
Sbjct: 327 SAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMD 370
>AK023308-1|BAB14518.1| 618|Homo sapiens protein ( Homo sapiens
cDNA FLJ13246 fis, clone OVARC1000682, highly similar to
PROCESSING ALPHA-1,2-MANNOSIDASE (EC 3.2.1.-). ).
Length = 618
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Query: 38 TAGFNILK---SLERPDIEISYLQMDITYTKSIIRLRHYIQDLD 78
+AG +IL +L I +SYL D+TY K ++ +R +Q +D
Sbjct: 117 SAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMD 160
>AF027156-1|AAC26169.1| 641|Homo sapiens alpha 1,2-mannosidase IB
protein.
Length = 641
Score = 30.3 bits (65), Expect = 7.7
Identities = 16/44 (36%), Positives = 26/44 (59%), Gaps = 3/44 (6%)
Query: 38 TAGFNILK---SLERPDIEISYLQMDITYTKSIIRLRHYIQDLD 78
+AG +IL +L I +SYL D+TY K ++ +R +Q +D
Sbjct: 327 SAGSSILAEFGTLHMEFIHLSYLTGDLTYYKKVMHIRKLLQKMD 370
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.136 0.391
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 38,359,740
Number of Sequences: 224733
Number of extensions: 1467432
Number of successful extensions: 3205
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 3099
Number of HSP's gapped (non-prelim): 72
length of query: 276
length of database: 73,234,838
effective HSP length: 89
effective length of query: 187
effective length of database: 53,233,601
effective search space: 9954683387
effective search space used: 9954683387
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 65 (30.3 bits)
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