Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002818-TA|BGIBMGA002818-PA|IPR012999|Pyridine
nucleotide-disulphide oxidoreductase, class I, active site,
IPR013027|FAD-dependent pyridine nucleotide-disulphide oxidoreductase,
IPR004099|Pyridine nucleotide-disulphide oxidoreductase dimerisation
region, IPR001327|Pyridine nucleotide-disulphide oxidoreductase,
NAD-binding region, IPR006338|Thioredoxin and glutathione reductase
selenoprotein, IPR001100|Pyridine nucleotide-disulphide
oxidoreductase, class I, IPR000815|Mercuric reductase
(462 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NNW7 Cluster: Thioredoxin reductase 2, mitochondrial ... 550 e-155
UniRef50_Q99MD6 Cluster: Thioredoxin and glutathione reductase; ... 521 e-146
UniRef50_Q16881 Cluster: Thioredoxin reductase 1, cytoplasmic pr... 512 e-144
UniRef50_Q17745 Cluster: Thioredoxin reductase 1; n=6; Bilateria... 468 e-130
UniRef50_P30635 Cluster: Probable glutathione reductase 2; n=2; ... 433 e-120
UniRef50_Q6KG49 Cluster: Mitochondrial thioredoxin reductase 2; ... 427 e-118
UniRef50_Q25861 Cluster: Thioredoxin reductase; n=14; Apicomplex... 409 e-112
UniRef50_A0E909 Cluster: Chromosome undetermined scaffold_83, wh... 407 e-112
UniRef50_Q8H6T2 Cluster: Thioredoxin reductase TR1; n=1; Chlamyd... 387 e-106
UniRef50_UPI0000F2E9A5 Cluster: PREDICTED: similar to extracellu... 384 e-105
UniRef50_A0C460 Cluster: Chromosome undetermined scaffold_148, w... 374 e-102
UniRef50_Q4UCW3 Cluster: Thioredoxin reductase, putative; n=3; P... 363 4e-99
UniRef50_UPI000150AB3A Cluster: Pyridine nucleotide-disulphide o... 359 7e-98
UniRef50_A0CQA5 Cluster: Chromosome undetermined scaffold_24, wh... 340 4e-92
UniRef50_UPI00006CFB8B Cluster: Pyridine nucleotide-disulphide o... 333 5e-90
UniRef50_Q4SQZ1 Cluster: Chromosome 11 SCAF14528, whole genome s... 302 1e-80
UniRef50_Q4UWG8 Cluster: Reductase; n=10; Gammaproteobacteria|Re... 265 1e-69
UniRef50_Q58E89 Cluster: MGC84926 protein; n=7; cellular organis... 260 6e-68
UniRef50_P00390 Cluster: Glutathione reductase, mitochondrial pr... 254 3e-66
UniRef50_Q60151 Cluster: Glutathione reductase; n=31; Bacteria|R... 251 3e-65
UniRef50_Q8DIH9 Cluster: Glutathione reductase; n=16; Cyanobacte... 250 4e-65
UniRef50_A1AVW4 Cluster: Pyridine nucleotide-disulphide oxidored... 248 2e-64
UniRef50_A1D1G1 Cluster: Glutathione reductase; n=7; cellular or... 246 1e-63
UniRef50_P41921 Cluster: Glutathione reductase; n=39; cellular o... 243 9e-63
UniRef50_Q5ZY02 Cluster: Glutathione reductase; n=4; Legionella ... 241 4e-62
UniRef50_P42770 Cluster: Glutathione reductase, chloroplast prec... 239 1e-61
UniRef50_Q2IA26 Cluster: Chloroplast glutathione reductase; n=1;... 237 3e-61
UniRef50_P23189 Cluster: Glutathione reductase; n=42; Proteobact... 237 6e-61
UniRef50_A3TUM1 Cluster: Glutathione-disulfide reductase; n=2; A... 234 3e-60
UniRef50_Q5FQ43 Cluster: Glutathione reductase; n=3; Acetobacter... 233 1e-59
UniRef50_P48638 Cluster: Glutathione reductase; n=57; Bacteria|R... 233 1e-59
UniRef50_A0ZGC8 Cluster: Glutathione reductase; n=2; Nostocaceae... 231 2e-59
UniRef50_A2C124 Cluster: Probable glutathione reductase; n=2; Pr... 229 9e-59
UniRef50_A4IXR1 Cluster: Glutathione-disulfide reductase; n=11; ... 229 1e-58
UniRef50_Q1GTU0 Cluster: Glutathione reductase; n=12; Bacteria|R... 229 2e-58
UniRef50_P39051 Cluster: Trypanothione reductase (EC 1.8.1.12) (... 223 1e-56
UniRef50_Q7V2B4 Cluster: Probable glutathione reductase; n=5; Pr... 220 5e-56
UniRef50_A1B892 Cluster: Pyridine nucleotide-disulphide oxidored... 218 3e-55
UniRef50_P48639 Cluster: Glutathione reductase; n=5; cellular or... 218 3e-55
UniRef50_Q5NN75 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 214 4e-54
UniRef50_Q6BPI1 Cluster: Glutathione reductase; n=6; Saccharomyc... 210 8e-53
UniRef50_O43998 Cluster: Glutathione reductase homolog; n=1; Tox... 204 3e-51
UniRef50_Q3UY43 Cluster: Adult male olfactory brain cDNA, RIKEN ... 200 5e-50
UniRef50_UPI0000E4A80A Cluster: PREDICTED: similar to thioredoxi... 199 1e-49
UniRef50_A3VZL9 Cluster: Glutathione-disulfide reductase; n=1; R... 196 8e-49
UniRef50_Q94655 Cluster: Glutathione reductase; n=11; Plasmodium... 192 2e-47
UniRef50_A6GLK6 Cluster: Glutathione reductase; n=1; Limnobacter... 192 2e-47
UniRef50_Q072K0 Cluster: Glutathione reductase; n=2; Papilionoid... 182 2e-44
UniRef50_Q59299 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 176 9e-43
UniRef50_Q0US44 Cluster: Putative uncharacterized protein; n=1; ... 175 3e-42
UniRef50_Q6ARJ3 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 168 3e-40
UniRef50_A3GI90 Cluster: Glutathione reductase; n=1; Pichia stip... 166 9e-40
UniRef50_A5UXL4 Cluster: Dihydrolipoamide dehydrogenase; n=3; Ch... 166 1e-39
UniRef50_P16171 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II... 166 1e-39
UniRef50_Q3VU31 Cluster: FAD-dependent pyridine nucleotide-disul... 164 4e-39
UniRef50_Q1LHF0 Cluster: FAD-dependent pyridine nucleotide-disul... 163 7e-39
UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6; Clost... 162 2e-38
UniRef50_Q1VLA0 Cluster: Dihydrolipoyl dehydrogenase; n=1; Psych... 159 1e-37
UniRef50_A0LAA4 Cluster: Dihydrolipoyl dehydrogenase; n=9; cellu... 159 1e-37
UniRef50_A7CCD3 Cluster: Pyridine nucleotide-disulphide oxidored... 158 3e-37
UniRef50_P09622 Cluster: Dihydrolipoyl dehydrogenase, mitochondr... 158 3e-37
UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13; Baci... 158 3e-37
UniRef50_Q1PWS8 Cluster: Similar to NAD(P) oxidoreductase, FAD-c... 155 2e-36
UniRef50_A1SH76 Cluster: Pyridine nucleotide-disulphide oxidored... 155 2e-36
UniRef50_Q0LM28 Cluster: Pyridine nucleotide-disulphide oxidored... 154 5e-36
UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2; Clost... 153 7e-36
UniRef50_P08332 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II... 153 7e-36
UniRef50_Q2RZZ0 Cluster: Mercuric reductase; n=1; Salinibacter r... 152 2e-35
UniRef50_A6WBN3 Cluster: Pyridine nucleotide-disulphide oxidored... 152 2e-35
UniRef50_P0A0E8 Cluster: Dihydrolipoyl dehydrogenase; n=46; Baci... 152 2e-35
UniRef50_Q5FK23 Cluster: Glutathione reductase; n=1; Lactobacill... 151 4e-35
UniRef50_Q2JK69 Cluster: Pyridine nucleotide-disulfide oxidoredu... 150 7e-35
UniRef50_O84561 Cluster: Dihydrolipoyl dehydrogenase; n=9; Chlam... 150 9e-35
UniRef50_P21880 Cluster: Dihydrolipoyl dehydrogenase; n=27; Baci... 150 9e-35
UniRef50_Q3ETT1 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacil... 149 2e-34
UniRef50_A5N930 Cluster: Dihydrolipoyl dehydrogenase; n=1; Clost... 149 2e-34
UniRef50_Q2S6F1 Cluster: Mercuric reductase; n=3; Bacteria|Rep: ... 147 5e-34
UniRef50_Q41E05 Cluster: FAD-dependent pyridine nucleotide-disul... 147 5e-34
UniRef50_Q28QN1 Cluster: FAD-dependent pyridine nucleotide-disul... 147 5e-34
UniRef50_Q9WYL2 Cluster: Dihydrolipoamide dehydrogenase; n=6; Ba... 147 6e-34
UniRef50_Q2NDS9 Cluster: Mercuric reductase, putative; n=2; Eryt... 146 8e-34
UniRef50_Q26GG1 Cluster: Dihydrolipoamide dehydrogenase; n=1; Fl... 146 8e-34
UniRef50_Q9RRW5 Cluster: Dihydrolipoyl dehydrogenase; n=4; Deino... 146 1e-33
UniRef50_Q2RHM5 Cluster: Dihydrolipoyl dehydrogenase; n=4; Clost... 146 1e-33
UniRef50_Q74A03 Cluster: Dihydrolipoyl dehydrogenase; n=2; Geoba... 146 1e-33
UniRef50_Q67B06 Cluster: Dihydrolipoyl dehydrogenase; n=22; Bact... 146 1e-33
UniRef50_Q1GQ53 Cluster: Mercuric reductase MerA; n=91; Bacteria... 145 2e-33
UniRef50_Q8F6S8 Cluster: Dihydrolipoyl dehydrogenase; n=30; Bact... 145 2e-33
UniRef50_Q5ZV78 Cluster: Mercuric reductase; n=5; Legionella pne... 144 3e-33
UniRef50_Q5UWH2 Cluster: Dihydrolipoyl dehydrogenase 3; n=6; Hal... 144 3e-33
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 144 6e-33
UniRef50_A4J8D3 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 144 6e-33
UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65; cell... 143 8e-33
UniRef50_Q8R9D9 Cluster: Dihydrolipoyl dehydrogenase; n=3; Therm... 143 1e-32
UniRef50_A6TMP2 Cluster: Dihydrolipoyl dehydrogenase; n=1; Alkal... 143 1e-32
UniRef50_Q8TIX6 Cluster: Glutathione reductase; n=6; Methanosarc... 143 1e-32
UniRef50_Q6MPR7 Cluster: Dihydrolipoyl dehydrogenase; n=2; Delta... 142 2e-32
UniRef50_Q9D8I4 Cluster: Adult male small intestine cDNA, RIKEN ... 140 5e-32
UniRef50_Q7NDN4 Cluster: Gll4201 protein; n=1; Gloeobacter viola... 140 5e-32
UniRef50_Q1AT12 Cluster: Dihydrolipoyl dehydrogenase; n=3; Bacte... 140 5e-32
UniRef50_A4BJ37 Cluster: Mercuric reductase; n=2; unclassified G... 140 5e-32
UniRef50_P30341 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II... 140 5e-32
UniRef50_Q5V791 Cluster: Mercuric reductase; n=1; Haloarcula mar... 140 7e-32
UniRef50_A3CSE1 Cluster: Pyridine nucleotide-disulphide oxidored... 139 1e-31
UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3; Cl... 138 2e-31
UniRef50_Q28MH1 Cluster: Pyridine nucleotide-disulphide oxidored... 138 3e-31
UniRef50_Q03HI1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 138 4e-31
UniRef50_Q8DD46 Cluster: Soluble pyridine nucleotide transhydrog... 138 4e-31
UniRef50_UPI000038D9FE Cluster: COG1249: Pyruvate/2-oxoglutarate... 137 5e-31
UniRef50_Q88SV9 Cluster: Glutathione reductase; n=10; Lactobacil... 137 5e-31
UniRef50_A0M205 Cluster: Dihydrolipoyl dehydrogenase; n=2; Bacte... 137 5e-31
UniRef50_Q6MC87 Cluster: Dihydrolipoyl dehydrogenase; n=1; Candi... 137 7e-31
UniRef50_A3UIQ0 Cluster: Probable glutathione reductase; n=1; Oc... 136 1e-30
UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3; Lacto... 136 2e-30
UniRef50_O66945 Cluster: Dihydrolipoyl dehydrogenase; n=2; Aquif... 136 2e-30
UniRef50_Q1R3M3 Cluster: Dihydrolipoyl dehydrogenase; n=4; Esche... 135 2e-30
UniRef50_Q03GQ4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 135 2e-30
UniRef50_A7CW98 Cluster: Pyridine nucleotide-disulphide oxidored... 135 2e-30
UniRef50_A3XHA5 Cluster: Regulatory protein; n=4; Flavobacteriac... 135 2e-30
UniRef50_Q11LG9 Cluster: Pyridine nucleotide-disulphide oxidored... 135 3e-30
UniRef50_A7JHZ5 Cluster: Soluble pyridine nucleotide transhydrog... 135 3e-30
UniRef50_Q4FXL9 Cluster: Dihydrolipoamide dehydrogenase, putativ... 135 3e-30
UniRef50_P66007 Cluster: Probable soluble pyridine nucleotide tr... 134 4e-30
UniRef50_P54533 Cluster: Dihydrolipoyl dehydrogenase; n=41; Firm... 134 4e-30
UniRef50_Q7UVC8 Cluster: Dihydrolipoyl dehydrogenase; n=3; Bacte... 134 5e-30
UniRef50_A3U327 Cluster: Regulatory protein; n=4; Alphaproteobac... 134 5e-30
UniRef50_Q18ZH8 Cluster: Dihydrolipoyl dehydrogenase; n=3; Desul... 134 6e-30
UniRef50_Q311Y4 Cluster: Mercuric reductase, putative; n=4; Delt... 133 8e-30
UniRef50_A3H831 Cluster: Pyridine nucleotide-disulphide oxidored... 133 1e-29
UniRef50_Q8DTC8 Cluster: Dihydrolipoyl dehydrogenase; n=2; Strep... 132 1e-29
UniRef50_Q4L6L9 Cluster: Dihydrolipoyl dehydrogenase; n=16; Stap... 132 1e-29
UniRef50_A6C4P3 Cluster: Dihydrolipoyl dehydrogenase; n=1; Planc... 132 1e-29
UniRef50_Q0W7Q8 Cluster: Dihydrolipoamide dehydrogenase; n=2; Eu... 132 1e-29
UniRef50_Q3XWK1 Cluster: FAD-dependent pyridine nucleotide-disul... 132 2e-29
UniRef50_Q1IIJ6 Cluster: Dihydrolipoyl dehydrogenase; n=4; Bacte... 132 2e-29
UniRef50_A1HU83 Cluster: Dihydrolipoyl dehydrogenase; n=1; Therm... 132 2e-29
UniRef50_Q9KES0 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacil... 132 2e-29
UniRef50_Q8Y768 Cluster: Lmo1433 protein; n=12; Listeria|Rep: Lm... 132 2e-29
UniRef50_Q1JWV4 Cluster: Pyridine nucleotide-disulphide oxidored... 132 2e-29
UniRef50_Q11PG6 Cluster: Pyridine nucleotide-disulphide-related ... 132 2e-29
UniRef50_Q047B7 Cluster: Glutathione reductase; n=4; Lactobacill... 132 2e-29
UniRef50_A7HBV5 Cluster: Dihydrolipoamide dehydrogenase; n=2; An... 132 2e-29
UniRef50_Q9YBC8 Cluster: Dihydrolipoyl dehydrogenase; n=2; Desul... 132 2e-29
UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7; Bacte... 131 3e-29
UniRef50_Q6AQZ1 Cluster: Related to mercuric reductase; n=17; Pr... 131 3e-29
UniRef50_A6U5L4 Cluster: Pyridine nucleotide-disulphide oxidored... 131 3e-29
UniRef50_A4FLD8 Cluster: Dihydrolipoyl dehydrogenase; n=2; Bacte... 131 3e-29
UniRef50_Q73M80 Cluster: Dihydrolipoyl dehydrogenase; n=1; Trepo... 131 4e-29
UniRef50_Q0AAN2 Cluster: Pyridine nucleotide-disulphide oxidored... 130 8e-29
UniRef50_A3XLG1 Cluster: Dihydrolipoamide dehydrogenase; n=3; Ba... 130 1e-28
UniRef50_Q8ZUT2 Cluster: Mercuric reductase; n=4; Thermoproteace... 130 1e-28
UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7; ro... 129 1e-28
UniRef50_Q7USN6 Cluster: Glutathione reductase; n=1; Pirellula s... 129 2e-28
UniRef50_Q189R5 Cluster: Dihydrolipoyl dehydrogenase; n=3; Clost... 129 2e-28
UniRef50_Q1KSF4 Cluster: Dihydrolipoyl dehydrogenase; n=25; cell... 128 2e-28
UniRef50_Q67SE4 Cluster: Dihydrolipoyl dehydrogenase; n=2; Lacto... 128 3e-28
UniRef50_UPI000023D207 Cluster: hypothetical protein FG05450.1; ... 128 4e-28
UniRef50_Q5QYX3 Cluster: Mercuric reductase, membrane-associated... 127 5e-28
UniRef50_Q1GHN7 Cluster: Dihydrolipoyl dehydrogenase; n=41; Bact... 127 5e-28
UniRef50_Q184K0 Cluster: Putative pyridine-nucleotide-disulfide ... 127 5e-28
UniRef50_Q0C555 Cluster: Pyridine nucleotide-disulfide oxidoredu... 127 5e-28
UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1; ... 127 7e-28
UniRef50_Q090H7 Cluster: Soluble pyridine nucleotide transhydrog... 126 9e-28
UniRef50_Q0F0Y4 Cluster: Soluble pyridine nucleotide transhydrog... 126 2e-27
UniRef50_A5EH40 Cluster: Putative mercuric reductase protein; n=... 126 2e-27
UniRef50_A2TYU9 Cluster: Regulatory protein; n=1; Polaribacter d... 126 2e-27
UniRef50_Q88ZF2 Cluster: Glutathione reductase; n=4; Lactobacill... 125 2e-27
UniRef50_Q38UF8 Cluster: Glutathione reductase; n=3; Lactobacill... 125 2e-27
UniRef50_Q1K1S1 Cluster: FAD-dependent pyridine nucleotide-disul... 125 2e-27
UniRef50_A0Q826 Cluster: Dihydrolipoamide dehydrogenase; n=7; Fr... 125 2e-27
UniRef50_Q6AAX8 Cluster: Pyridine nucleotide-disulphide oxidored... 125 3e-27
UniRef50_Q68VU4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick... 125 3e-27
UniRef50_Q1K470 Cluster: Pyridine nucleotide-disulphide oxidored... 125 3e-27
UniRef50_Q8RDF1 Cluster: Dihydrolipoyl dehydrogenase; n=3; Therm... 124 4e-27
UniRef50_Q0AVI0 Cluster: Dihydrolipoyl dehydrogenase; n=1; Syntr... 124 4e-27
UniRef50_Q1Q2Y9 Cluster: Dihydrolipoyl dehydrogenase; n=1; Candi... 124 5e-27
UniRef50_A7GZF3 Cluster: Probable pyridine nucleotide-disulfide ... 124 5e-27
UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1; Mycop... 124 7e-27
UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide oxidored... 124 7e-27
UniRef50_Q82L58 Cluster: Dihydrolipoyl dehydrogenase; n=1; Strep... 123 9e-27
UniRef50_Q1GLP7 Cluster: Pyridine nucleotide-disulphide oxidored... 123 9e-27
UniRef50_A3DNK1 Cluster: Dihydrolipoamide dehydrogenase; n=1; St... 123 9e-27
UniRef50_P0A9P3 Cluster: Dihydrolipoyl dehydrogenase; n=182; Bac... 123 9e-27
UniRef50_Q9CH92 Cluster: Glutathione reductase; n=3; Lactococcus... 123 1e-26
UniRef50_Q8CQA3 Cluster: Dihydrolipoyl dehydrogenase; n=4; Staph... 123 1e-26
UniRef50_Q24PW4 Cluster: Dihydrolipoyl dehydrogenase; n=1; Desul... 123 1e-26
UniRef50_A6Q9K6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 123 1e-26
UniRef50_A5KTA3 Cluster: Pyridine nucleotide-disulphide oxidored... 123 1e-26
UniRef50_Q97C54 Cluster: Mercuric reductase; n=2; Thermoplasma|R... 123 1e-26
UniRef50_Q8F290 Cluster: Dihydrolipoyl dehydrogenase; n=4; Lepto... 122 2e-26
UniRef50_P50970 Cluster: Dihydrolipoyl dehydrogenase; n=25; Prot... 122 2e-26
UniRef50_Q9I1L9 Cluster: Dihydrolipoyl dehydrogenase; n=54; Prot... 122 2e-26
UniRef50_Q8CU56 Cluster: Dihydrolipoyl dehydrogenase; n=3; Bacil... 122 2e-26
UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3; Achol... 122 2e-26
UniRef50_UPI0000ECC431 Cluster: Glutathione reductase, mitochond... 122 3e-26
UniRef50_A7HHC7 Cluster: Pyridine nucleotide-disulphide oxidored... 122 3e-26
UniRef50_Q8KB36 Cluster: Dihydrolipoamide dehydrogenase; n=2; Ch... 121 4e-26
UniRef50_Q1IMV9 Cluster: Dihydrolipoyl dehydrogenase; n=2; Bacte... 121 4e-26
UniRef50_Q41CB3 Cluster: FAD-dependent pyridine nucleotide-disul... 121 5e-26
UniRef50_Q8PS09 Cluster: Dihydrolipoamide dehydrogenase; n=5; Eu... 121 5e-26
UniRef50_A4CGZ8 Cluster: Regulatory protein; n=5; Flavobacteriac... 120 6e-26
UniRef50_A0SNY8 Cluster: Mercuric reductase; n=1; uncultured eur... 120 6e-26
UniRef50_UPI00015BC7B4 Cluster: UPI00015BC7B4 related cluster; n... 120 8e-26
UniRef50_Q9RKH2 Cluster: Putative oxidoreductase; n=1; Streptomy... 120 8e-26
UniRef50_Q8F4C6 Cluster: Dihydrolipoamide dehydrogenase; n=4; Le... 120 8e-26
UniRef50_Q11NC9 Cluster: Dihydrolipoyl dehydrogenase; n=4; Alpha... 120 8e-26
UniRef50_A7I8G1 Cluster: Pyridine nucleotide-disulphide oxidored... 120 8e-26
UniRef50_A7IDF4 Cluster: Pyridine nucleotide-disulphide oxidored... 120 1e-25
UniRef50_Q9S2Q6 Cluster: Dihydrolipoyl dehydrogenase; n=32; Bact... 119 1e-25
UniRef50_Q5FGZ4 Cluster: Dihydrolipoyl dehydrogenase; n=11; Rick... 119 1e-25
UniRef50_A1SYC1 Cluster: Dihydrolipoyl dehydrogenase; n=3; Prote... 119 1e-25
UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide tr... 119 2e-25
UniRef50_Q50068 Cluster: Dihydrolipoyl dehydrogenase; n=33; Acti... 119 2e-25
UniRef50_A3EPX8 Cluster: Dihydrolipoyl dehydrogenase; n=1; Lepto... 118 2e-25
UniRef50_Q2JND9 Cluster: Dihydrolipoyl dehydrogenase; n=3; Cyano... 118 3e-25
UniRef50_Q2B857 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ba... 118 3e-25
UniRef50_A3ESJ6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 118 4e-25
UniRef50_Q6LLT9 Cluster: Soluble pyridine nucleotide transhydrog... 118 4e-25
UniRef50_Q74AD0 Cluster: Dihydrolipoyl dehydrogenase; n=17; Prot... 117 8e-25
UniRef50_Q01WF2 Cluster: FAD-dependent pyridine nucleotide-disul... 117 8e-25
UniRef50_Q8K9T7 Cluster: Dihydrolipoyl dehydrogenase; n=33; Gamm... 117 8e-25
UniRef50_A5IAB6 Cluster: Pyridine nucleotide-disulfide oxidoredu... 116 1e-24
UniRef50_A7BE73 Cluster: Putative uncharacterized protein; n=1; ... 116 2e-24
UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide transhydrog... 116 2e-24
UniRef50_A3TPL4 Cluster: Pyridine nucleotide-disulphide oxidored... 116 2e-24
UniRef50_P52992 Cluster: Dihydrolipoyl dehydrogenase; n=34; root... 116 2e-24
UniRef50_Q98C99 Cluster: Mercuric reductase; n=4; Proteobacteria... 115 2e-24
UniRef50_Q03XL9 Cluster: Glutathione reductase; n=1; Leuconostoc... 115 3e-24
UniRef50_Q7MW44 Cluster: Dihydrolipoyl dehydrogenase; n=10; Bact... 114 4e-24
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My... 114 5e-24
UniRef50_A7EZF7 Cluster: Putative uncharacterized protein; n=1; ... 113 7e-24
UniRef50_Q8NLD1 Cluster: Dihydrolipoamide dehydrogenase/glutathi... 113 1e-23
UniRef50_A6G2P8 Cluster: Dihydrolipoamide dehydrogenase; n=1; Pl... 113 1e-23
UniRef50_A4MI92 Cluster: Pyridine nucleotide-disulphide oxidored... 113 1e-23
UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component dih... 112 2e-23
UniRef50_Q88W40 Cluster: Glutathione reductase; n=2; Bacilli|Rep... 111 3e-23
UniRef50_A6CEV1 Cluster: Glutathione reductase; n=1; Planctomyce... 111 3e-23
UniRef50_A7D615 Cluster: Pyridine nucleotide-disulphide oxidored... 111 3e-23
UniRef50_Q9YBZ2 Cluster: Mercuric reductase; n=1; Aeropyrum pern... 110 7e-23
UniRef50_A2F0F6 Cluster: Dihydrolipoyl dehydrogenase; n=2; Trich... 110 9e-23
UniRef50_A7IAT2 Cluster: FAD-dependent pyridine nucleotide-disul... 110 9e-23
UniRef50_Q8VPK7 Cluster: Dihydrolipoamide dehydrogenase; n=43; S... 109 2e-22
UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase e... 109 2e-22
UniRef50_A1W7R7 Cluster: Dihydrolipoamide dehydrogenase; n=58; B... 109 2e-22
UniRef50_A7HGF8 Cluster: Pyridine nucleotide-disulphide oxidored... 108 3e-22
UniRef50_A5FRC9 Cluster: FAD-dependent pyridine nucleotide-disul... 108 3e-22
UniRef50_Q6L2F3 Cluster: Mercuric reductase; n=3; Thermoplasmata... 108 3e-22
UniRef50_P57303 Cluster: Dihydrolipoyl dehydrogenase; n=10; Bact... 108 3e-22
UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex,... 107 5e-22
UniRef50_A6DK63 Cluster: Dihydrolipoamide dehydrogenase; n=1; Le... 107 5e-22
UniRef50_A5UY00 Cluster: FAD-dependent pyridine nucleotide-disul... 107 5e-22
UniRef50_A1S189 Cluster: FAD-dependent pyridine nucleotide-disul... 107 5e-22
UniRef50_Q74DK1 Cluster: Mercuric reductase; n=4; Bacteria|Rep: ... 107 8e-22
UniRef50_Q2SKE2 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 107 8e-22
UniRef50_A3I4Y3 Cluster: Acetoin dehydrogenase, E3 component, di... 106 1e-21
UniRef50_Q97Z19 Cluster: Dihydrolipoamide dehydrogenase; n=4; Su... 106 1e-21
UniRef50_Q6NIX1 Cluster: Dihydrolipoamide dehydrogenase; n=21; A... 106 1e-21
UniRef50_Q7P4B5 Cluster: Mercuric reductase; n=3; Fusobacterium ... 106 1e-21
UniRef50_A0R0K9 Cluster: Oxidoreductase; n=1; Mycobacterium smeg... 106 1e-21
UniRef50_A0FRY7 Cluster: Pyridine nucleotide-disulphide oxidored... 105 2e-21
UniRef50_Q2VHK2 Cluster: Oxidoreductase; n=11; Lactobacillales|R... 105 2e-21
UniRef50_Q115D3 Cluster: Pyridine nucleotide-disulphide oxidored... 105 2e-21
UniRef50_P75393 Cluster: Dihydrolipoyl dehydrogenase; n=6; Mycop... 105 2e-21
UniRef50_Q9KG96 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacil... 105 3e-21
UniRef50_A0B2P1 Cluster: Pyridine nucleotide-disulphide oxidored... 105 3e-21
UniRef50_Q8E285 Cluster: Pyridine nucleotide-disulphide oxidored... 104 4e-21
UniRef50_Q311A9 Cluster: 2-oxoglutarate dehydrogenase, E3 compon... 104 6e-21
UniRef50_A0L7L9 Cluster: Dihydrolipoyl dehydrogenase; n=1; Magne... 104 6e-21
UniRef50_A2R0R4 Cluster: Catalytic activity: Hg + NADP(+) + H(+)... 104 6e-21
UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoam... 103 8e-21
UniRef50_Q4N0C2 Cluster: Dihydrolipoyl dehydrogenase; n=2; Theil... 103 8e-21
UniRef50_P73059 Cluster: Mercuric reductase; n=11; Bacteria|Rep:... 103 1e-20
UniRef50_A1UEQ3 Cluster: Pyridine nucleotide-disulphide oxidored... 103 1e-20
UniRef50_UPI00015BD547 Cluster: UPI00015BD547 related cluster; n... 103 1e-20
UniRef50_Q6KCB6 Cluster: Dihydrolipoyl dehydrogenase; n=8; Plasm... 103 1e-20
UniRef50_A0J8I0 Cluster: FAD-dependent pyridine nucleotide-disul... 102 2e-20
UniRef50_O54274 Cluster: ORF503 protein; n=6; Staphylococcus|Rep... 102 2e-20
UniRef50_A4VK61 Cluster: Dihydrolipoamide dehydrogenase 3; n=1; ... 102 2e-20
UniRef50_A6CLP9 Cluster: Pyruvate dehydrogenase E3; n=1; Bacillu... 101 4e-20
UniRef50_A5EK01 Cluster: Dihydrolipoyl dehydrogenase; n=22; Bact... 101 4e-20
UniRef50_P77212 Cluster: Probable pyridine nucleotide-disulfide ... 101 4e-20
UniRef50_Q1K375 Cluster: FAD-dependent pyridine nucleotide-disul... 101 5e-20
UniRef50_A4YI59 Cluster: Pyridine nucleotide-disulphide oxidored... 101 5e-20
UniRef50_UPI0000510280 Cluster: COG1249: Pyruvate/2-oxoglutarate... 100 7e-20
UniRef50_Q97PL8 Cluster: Oxidoreductase, pyridine nucleotide-dis... 100 7e-20
UniRef50_A5CS71 Cluster: Putative oxidoreductase; n=1; Clavibact... 99 1e-19
UniRef50_A5HII0 Cluster: Glutathione reductase; n=4; Magnoliophy... 99 1e-19
UniRef50_Q02733 Cluster: Increased recombination centers protein... 99 1e-19
UniRef50_Q5ZZX0 Cluster: Dihydrolipoamide dehydrogenase; n=6; My... 100 2e-19
UniRef50_Q98RI8 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=1; My... 99 2e-19
UniRef50_Q8KCW2 Cluster: Dihydrolipoyl dehydrogenase; n=11; Chlo... 99 2e-19
UniRef50_Q92Q96 Cluster: Dihydrolipoyl dehydrogenase; n=15; Alph... 99 3e-19
UniRef50_A4T107 Cluster: Pyridine nucleotide-disulphide oxidored... 99 3e-19
UniRef50_Q7NCV5 Cluster: Glr2871 protein; n=3; Cyanobacteria|Rep... 98 4e-19
UniRef50_A3ZMG9 Cluster: Mercuric reductase; n=1; Blastopirellul... 98 4e-19
UniRef50_A3ZHU0 Cluster: Probable pyridine nucleotide-disulfide ... 97 7e-19
UniRef50_Q746U4 Cluster: Mercuric reductase; n=5; Geobacter|Rep:... 97 9e-19
UniRef50_Q2GDU8 Cluster: Dihydrolipoyl dehydrogenase; n=1; Neori... 97 9e-19
UniRef50_A4AEI6 Cluster: Putative oxidoreductase; n=1; marine ac... 96 2e-18
UniRef50_A1SIG2 Cluster: FAD-dependent pyridine nucleotide-disul... 96 2e-18
UniRef50_Q4Q5Z7 Cluster: 2-oxoglutarate dehydrogenase, e3 compon... 96 2e-18
UniRef50_A4YFQ3 Cluster: Pyridine nucleotide-disulphide oxidored... 96 2e-18
UniRef50_Q1AV54 Cluster: Pyridine nucleotide-disulphide oxidored... 95 3e-18
UniRef50_Q97XZ3 Cluster: Dihydrolipoamide dehydrogenase; n=2; Su... 95 5e-18
UniRef50_Q4J868 Cluster: Mercuric reductase; n=10; Archaea|Rep: ... 95 5e-18
UniRef50_Q13KM1 Cluster: Putative dihydrolipoamide dehydrogenase... 94 6e-18
UniRef50_Q6A6B6 Cluster: Pyridine nucleotide-disulphide oxidored... 94 8e-18
UniRef50_Q2FS82 Cluster: FAD-dependent pyridine nucleotide-disul... 93 2e-17
UniRef50_A6SWJ7 Cluster: Mercury(II) reductase; n=50; Bacteria|R... 91 6e-17
UniRef50_A6Q9K4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 91 6e-17
UniRef50_A5UKW4 Cluster: Dihydrolipoamide dehydrogenase; n=1; Me... 90 1e-16
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 90 1e-16
UniRef50_Q9KNU2 Cluster: Pyridine nucleotide-disulfide oxidoredu... 90 1e-16
UniRef50_Q83HF4 Cluster: Dihydrolipoamide dehydrogenase; n=2; Tr... 89 2e-16
UniRef50_Q1EZ89 Cluster: FAD-dependent pyridine nucleotide-disul... 89 2e-16
UniRef50_Q83N49 Cluster: Pyridine nucleotide-disulphide oxidored... 89 2e-16
UniRef50_A2RPR6 Cluster: 2-oxoglutarate dehydrogenase, E3 compon... 88 4e-16
UniRef50_A2RNK4 Cluster: Pyridine nucleotide-disulfide oxidoredu... 88 4e-16
UniRef50_Q41EB7 Cluster: FAD-dependent pyridine nucleotide-disul... 88 5e-16
UniRef50_Q8TE01 Cluster: DERP12; n=1; Homo sapiens|Rep: DERP12 -... 88 5e-16
UniRef50_Q97CK3 Cluster: Dihydrolipoyl dehydrogenase; n=4; Therm... 87 7e-16
UniRef50_A5FUY9 Cluster: Pyridine nucleotide-disulphide oxidored... 86 2e-15
UniRef50_Q9HLL9 Cluster: Dihydrolipoamide dehydrogenase componen... 86 2e-15
UniRef50_Q8G5E0 Cluster: Dihydrolipoyl dehydrogenase; n=4; Bifid... 85 4e-15
UniRef50_A3CSS3 Cluster: FAD-dependent pyridine nucleotide-disul... 85 4e-15
UniRef50_Q0W154 Cluster: Pyruvate dehydrogenase complex E3, dihy... 85 5e-15
UniRef50_Q6F7X9 Cluster: Putative pyridine nucleotide-disulfide ... 84 9e-15
UniRef50_A5IXN5 Cluster: Dihydrolipoyl dehydrogenase; n=1; Mycop... 84 9e-15
UniRef50_Q3JCH1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 83 2e-14
UniRef50_Q8ZUR5 Cluster: Pyruvate dehydrogenase E3; n=2; Pyrobac... 83 2e-14
UniRef50_A3M5D5 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ac... 81 5e-14
UniRef50_Q5UXD9 Cluster: Dihydrolipoamide dehydrogenase; n=3; Ha... 81 5e-14
UniRef50_O27685 Cluster: Dihydrolipoamide dehydrogenase; n=1; Me... 81 5e-14
UniRef50_Q56839 Cluster: 2-oxopropyl-CoM reductase, carboxylatin... 80 1e-13
UniRef50_A7D8C3 Cluster: FAD-dependent pyridine nucleotide-disul... 79 2e-13
UniRef50_Q2HI16 Cluster: Putative uncharacterized protein; n=1; ... 79 2e-13
UniRef50_Q8TX29 Cluster: Dihydrolipoamide dehydrogenase; n=1; Me... 79 2e-13
UniRef50_Q1DFL4 Cluster: Mercuric reductase, truncated; n=1; Myx... 79 2e-13
UniRef50_Q8G3X6 Cluster: Possible class I pyridine nucleotide-di... 79 3e-13
UniRef50_Q2JF62 Cluster: Pyridine nucleotide-disulphide oxidored... 79 3e-13
UniRef50_Q0RVL5 Cluster: Dihydrolipoyl dehydrogenanse; n=1; Rhod... 78 6e-13
UniRef50_Q978K3 Cluster: Pyruvate dehydrogenase E3 / dihydrolipo... 77 1e-12
UniRef50_A1U0G0 Cluster: FAD-dependent pyridine nucleotide-disul... 76 2e-12
UniRef50_Q5P1X0 Cluster: Putative uncharacterized protein; n=1; ... 75 3e-12
UniRef50_A5WGB8 Cluster: Pyridine nucleotide-disulphide oxidored... 75 3e-12
UniRef50_Q2NFE3 Cluster: Predicted dihydrolipoamide dehydrogenas... 75 3e-12
UniRef50_Q8YQ97 Cluster: Mercuric reductase; n=4; Nostocaceae|Re... 75 4e-12
UniRef50_Q5WE89 Cluster: Acetoin dehydrogenase E3 component; n=1... 75 5e-12
UniRef50_Q8DWC4 Cluster: Putative glutathione reductase; n=1; St... 74 9e-12
UniRef50_A0H3T5 Cluster: FAD-dependent pyridine nucleotide-disul... 74 9e-12
UniRef50_Q5VGY1 Cluster: Dihydrolipoamide dehydrogenase; n=3; Pl... 73 1e-11
UniRef50_A2ST66 Cluster: FAD-dependent pyridine nucleotide-disul... 73 2e-11
UniRef50_Q6SKC7 Cluster: Dihydrolipoamide dehydrogenase-like pro... 71 5e-11
UniRef50_Q584K1 Cluster: Dihydrolipoamide dehydrogenase, putativ... 71 5e-11
UniRef50_Q6S4W1 Cluster: Dihydrolipoamide dehydrogenase precurso... 71 9e-11
UniRef50_A3VQD6 Cluster: Dihydrolipoamide dehydrogenase; n=5; Al... 70 1e-10
UniRef50_A4BQ38 Cluster: Dihydrolipoamide dehydrogenase; n=1; Ni... 69 2e-10
UniRef50_Q4L3S1 Cluster: Mercuric reductase homologue; n=2; Stap... 69 3e-10
UniRef50_A3ERW1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 69 3e-10
UniRef50_Q4JCC0 Cluster: Dihydrolipoamide dehydrogenase; n=4; Su... 69 3e-10
UniRef50_Q2NEC3 Cluster: Predicted NAD(FAD)-dependent dehydrogen... 69 3e-10
UniRef50_A5GRM0 Cluster: Putative soluble pyridine nucleotide tr... 66 2e-09
UniRef50_UPI0001597145 Cluster: NasB; n=1; Bacillus amyloliquefa... 65 3e-09
UniRef50_Q82WB8 Cluster: Pyridine nucleotide-disulfide oxidoredu... 65 3e-09
UniRef50_Q2JEH1 Cluster: Pyridine nucleotide-disulphide oxidored... 65 4e-09
UniRef50_Q7RRZ4 Cluster: Dihydrolipoamide dehydrogenase; n=3; Pl... 65 4e-09
UniRef50_O29847 Cluster: NADH oxidase; n=2; cellular organisms|R... 65 4e-09
UniRef50_A7H8D2 Cluster: FAD-dependent pyridine nucleotide-disul... 64 6e-09
UniRef50_Q4Q5Z6 Cluster: Acetoin dehydrogenase e3 component-like... 64 6e-09
UniRef50_Q9V0X9 Cluster: NoxA-2 NADH oxidase; n=4; Thermococcace... 64 6e-09
UniRef50_A4XHJ3 Cluster: FAD-dependent pyridine nucleotide-disul... 64 7e-09
UniRef50_A1SIE7 Cluster: Pyridine nucleotide-disulphide oxidored... 64 1e-08
UniRef50_Q8VKD9 Cluster: Mercuric reductase/transcriptional regu... 63 1e-08
UniRef50_Q1JZ87 Cluster: FAD-dependent pyridine nucleotide-disul... 62 2e-08
UniRef50_UPI000051037B Cluster: COG1249: Pyruvate/2-oxoglutarate... 62 3e-08
UniRef50_A7BMW7 Cluster: Dihydrolipoamide dehydrogenase; n=1; Be... 62 3e-08
UniRef50_A0BNL9 Cluster: Chromosome undetermined scaffold_119, w... 62 3e-08
UniRef50_P42433 Cluster: Assimilatory nitrate reductase electron... 62 3e-08
UniRef50_Q83EN9 Cluster: Pyridine nucleotide-disulfide oxidoredu... 62 4e-08
UniRef50_A2VRE9 Cluster: Dihydrolipoamide dehydrogenase; n=2; Bu... 62 4e-08
UniRef50_Q8ZVB1 Cluster: NADH oxidase; n=5; Thermoproteaceae|Rep... 62 4e-08
UniRef50_A7B900 Cluster: Putative uncharacterized protein; n=1; ... 61 7e-08
UniRef50_Q1Q0R7 Cluster: Similar to pyridine nucleotide-disulphi... 60 9e-08
UniRef50_UPI00015BAF0C Cluster: FAD-dependent pyridine nucleotid... 60 1e-07
UniRef50_Q31FJ0 Cluster: FAD-dependent pyridine nucleotide-disul... 60 2e-07
UniRef50_A1RWH3 Cluster: FAD-dependent pyridine nucleotide-disul... 60 2e-07
UniRef50_O05940 Cluster: Probable dihydrolipoyl dehydrogenase; n... 60 2e-07
UniRef50_Q3A7F5 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 59 2e-07
UniRef50_Q3A4H5 Cluster: Dihydrolipoamide dehydrogenase (E3) com... 59 2e-07
UniRef50_Q19655 Cluster: Putative uncharacterized protein F20D6.... 59 3e-07
UniRef50_Q3Y0G7 Cluster: FAD-dependent pyridine nucleotide-disul... 58 4e-07
UniRef50_Q9UYU5 Cluster: Coenzyme A disulfide reductase; n=6; Eu... 58 4e-07
UniRef50_A0IMP2 Cluster: FAD-dependent pyridine nucleotide-disul... 58 5e-07
UniRef50_Q3Y1R2 Cluster: FAD-dependent pyridine nucleotide-disul... 58 6e-07
UniRef50_A6WF52 Cluster: FAD-dependent pyridine nucleotide-disul... 58 6e-07
UniRef50_Q8R6T3 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 57 9e-07
UniRef50_A7LUS3 Cluster: Putative uncharacterized protein; n=1; ... 57 9e-07
UniRef50_A5ZWV3 Cluster: Putative uncharacterized protein; n=1; ... 57 9e-07
UniRef50_Q82ZQ9 Cluster: Coenzyme A disulfide reductase; n=9; Ba... 57 1e-06
UniRef50_A7BTB7 Cluster: Dihydrolipoyl dehydrogenase; n=1; Beggi... 57 1e-06
UniRef50_A1I9B3 Cluster: Putative ferredoxin-NAD+ reductase 1; n... 57 1e-06
UniRef50_Q8U1K9 Cluster: NADH oxidase /nitrite reductase; n=4; c... 57 1e-06
UniRef50_A5UK17 Cluster: Thioredoxin reductase (NADPH), TrxB; n=... 57 1e-06
UniRef50_P08655 Cluster: Uncharacterized 19.7 kDa protein in mer... 57 1e-06
UniRef50_Q39D64 Cluster: FAD-dependent pyridine nucleotide-disul... 56 1e-06
UniRef50_Q4CB64 Cluster: FAD-dependent pyridine nucleotide-disul... 56 1e-06
UniRef50_Q0LN20 Cluster: FAD-dependent pyridine nucleotide-disul... 56 2e-06
UniRef50_A0LCP2 Cluster: Pyridine nucleotide-disulphide oxidored... 56 2e-06
UniRef50_UPI00003835AA Cluster: COG0446: Uncharacterized NAD(FAD... 55 3e-06
UniRef50_Q9M5K2-2 Cluster: Isoform 2 of Q9M5K2 ; n=1; Arabidopsi... 55 3e-06
UniRef50_Q2RIY5 Cluster: FAD-dependent pyridine nucleotide-disul... 55 3e-06
UniRef50_Q926L9 Cluster: Pli0040 protein; n=5; Bacilli|Rep: Pli0... 54 6e-06
UniRef50_A3H9W2 Cluster: FAD-dependent pyridine nucleotide-disul... 54 6e-06
UniRef50_Q8DFP1 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 54 8e-06
UniRef50_Q1FP75 Cluster: FAD-dependent pyridine nucleotide-disul... 54 8e-06
UniRef50_Q0AVX3 Cluster: NADH oxidase; n=1; Syntrophomonas wolfe... 54 8e-06
UniRef50_A0GAF2 Cluster: FAD-dependent pyridine nucleotide-disul... 54 8e-06
UniRef50_Q58065 Cluster: Putative NADH oxidase; n=7; Euryarchaeo... 54 8e-06
UniRef50_Q3T557 Cluster: NADH oxidase-like protein; n=1; Acidith... 54 1e-05
UniRef50_Q88X11 Cluster: NADH peroxidase; n=1; Lactobacillus pla... 53 1e-05
UniRef50_Q6MN28 Cluster: Putative NAD(FAD)-dependent dehydrogena... 53 1e-05
UniRef50_Q83WM9 Cluster: Thioredoxin reductase; n=4; Desulfovibr... 53 1e-05
UniRef50_Q11ZY3 Cluster: FAD-dependent pyridine nucleotide-disul... 53 1e-05
UniRef50_A2SM33 Cluster: Putative rubredoxin reductase; n=1; Met... 53 1e-05
UniRef50_A1SC89 Cluster: FAD-dependent pyridine nucleotide-disul... 53 1e-05
UniRef50_A0LQI9 Cluster: FAD-dependent pyridine nucleotide-disul... 53 1e-05
UniRef50_A1AWX1 Cluster: Nitrite reductase (NAD(P)H), large subu... 53 2e-05
UniRef50_O28718 Cluster: Thioredoxin reductase; n=1; Archaeoglob... 53 2e-05
UniRef50_A1RR43 Cluster: FAD-dependent pyridine nucleotide-disul... 53 2e-05
UniRef50_Q6FB26 Cluster: Putative nitrate reductase (Electron tr... 52 2e-05
UniRef50_Q46UP9 Cluster: FAD-dependent pyridine nucleotide-disul... 52 2e-05
UniRef50_Q2RKJ7 Cluster: FAD-dependent pyridine nucleotide-disul... 52 2e-05
UniRef50_A4XLJ4 Cluster: FAD-dependent pyridine nucleotide-disul... 52 2e-05
UniRef50_P42454 Cluster: Rubredoxin-NAD(+) reductase; n=4; Acine... 52 2e-05
UniRef50_Q192U1 Cluster: FAD-dependent pyridine nucleotide-disul... 52 4e-05
UniRef50_Q15TG8 Cluster: FAD-dependent pyridine nucleotide-disul... 52 4e-05
UniRef50_Q5V6K6 Cluster: NADH oxidase; n=2; Halobacteriaceae|Rep... 52 4e-05
UniRef50_Q5P0H4 Cluster: Phenylglyoxylate:acceptor oxidoreductas... 51 6e-05
UniRef50_Q5FQ61 Cluster: Rubredoxin-NAD(+) reductase; n=1; Gluco... 51 6e-05
UniRef50_Q0S8H6 Cluster: Reductase; n=3; Corynebacterineae|Rep: ... 51 6e-05
UniRef50_Q6NFY7 Cluster: Putative oxidase; n=4; Actinobacteria (... 51 7e-05
UniRef50_Q602Q8 Cluster: Pyridine nucleotide-disulphide oxidored... 51 7e-05
UniRef50_Q2RRY6 Cluster: NADH peroxidase precursor; n=1; Rhodosp... 51 7e-05
UniRef50_Q11NC3 Cluster: Pyridine nucleotide-disulphide oxidored... 51 7e-05
UniRef50_Q0LDK4 Cluster: FAD-dependent pyridine nucleotide-disul... 51 7e-05
UniRef50_A4AU47 Cluster: NADH oxidase; n=14; cellular organisms|... 51 7e-05
UniRef50_UPI00015B4E99 Cluster: PREDICTED: similar to disulfide ... 50 1e-04
UniRef50_Q6AQU4 Cluster: Related to NADH oxidase; n=1; Desulfota... 50 1e-04
UniRef50_A4SHR1 Cluster: NADH oxidase, water-forming; n=2; Aerom... 50 1e-04
UniRef50_A1WCS6 Cluster: FAD-dependent pyridine nucleotide-disul... 50 1e-04
UniRef50_A0G6B4 Cluster: FAD-dependent pyridine nucleotide-disul... 50 1e-04
UniRef50_O58643 Cluster: 397aa long hypothetical NADH oxidase; n... 50 1e-04
UniRef50_Q4L4Y7 Cluster: Coenzyme A disulfide reductase; n=16; S... 50 1e-04
UniRef50_Q74DS8 Cluster: Pyridine nucleotide-disulphide oxidored... 50 2e-04
UniRef50_Q0AVQ5 Cluster: FAD-dependent pyridine nucleotide-disul... 50 2e-04
UniRef50_A5KJ20 Cluster: Putative uncharacterized protein; n=2; ... 50 2e-04
UniRef50_A5IY35 Cluster: NADH oxidase; n=4; Mycoplasma|Rep: NADH... 50 2e-04
UniRef50_Q2LQ41 Cluster: Pyridine nucleotide oxidoreductase; n=1... 49 2e-04
UniRef50_Q1JZA8 Cluster: FAD-dependent pyridine nucleotide-disul... 49 2e-04
UniRef50_A5WH60 Cluster: Rubredoxin; n=1; Psychrobacter sp. PRwf... 49 2e-04
UniRef50_Q2GUL7 Cluster: Putative uncharacterized protein; n=7; ... 49 2e-04
UniRef50_A6VZ49 Cluster: FAD-dependent pyridine nucleotide-disul... 49 3e-04
UniRef50_A0Y5X5 Cluster: Nitrite reductase, large subunit, NAD(P... 49 3e-04
UniRef50_Q64E99 Cluster: NADH oxidase; n=1; uncultured archaeon ... 49 3e-04
UniRef50_Q8D722 Cluster: Rhodanese-related sulfurtransferase; n=... 48 4e-04
UniRef50_Q0RQF2 Cluster: Putative oxidoreductase; putative metal... 48 4e-04
UniRef50_A6P1A8 Cluster: Rubredoxin; n=1; Bacteroides capillosus... 48 4e-04
UniRef50_A5WFQ2 Cluster: Nitrite reductase (NAD(P)H), large subu... 48 4e-04
UniRef50_A0YLQ6 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 48 4e-04
UniRef50_Q9HJX5 Cluster: NADH peroxidase related protein; n=2; T... 48 4e-04
UniRef50_P42435 Cluster: Nitrite reductase [NAD(P)H]; n=34; Bact... 48 4e-04
UniRef50_Q8R8V6 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 48 5e-04
UniRef50_O67007 Cluster: NADH oxidase; n=2; Aquifex aeolicus|Rep... 48 5e-04
UniRef50_A5TUD7 Cluster: NADH dehydrogenase; n=3; Fusobacterium ... 48 5e-04
UniRef50_A3Z853 Cluster: NADH oxidase; n=1; Synechococcus sp. RS... 48 5e-04
UniRef50_A3JDB0 Cluster: Putative pyridine nucleotide-disulfide ... 48 5e-04
UniRef50_A2W5Q1 Cluster: Putative uncharacterized protein; n=3; ... 48 5e-04
UniRef50_Q1ARZ7 Cluster: FAD-dependent pyridine nucleotide-disul... 48 7e-04
UniRef50_A3J8L0 Cluster: NAD(P)H-nitrite reductase; n=26; Proteo... 48 7e-04
UniRef50_A3DBW2 Cluster: FAD-dependent pyridine nucleotide-disul... 48 7e-04
UniRef50_A0JSP4 Cluster: Pyridine nucleotide-disulphide oxidored... 48 7e-04
UniRef50_Q2KZL2 Cluster: Putative ferredoxin reductase; n=1; Bor... 47 0.001
UniRef50_A6L317 Cluster: Pyridine nucleotide-disulphide oxidored... 47 0.001
UniRef50_A4G2V4 Cluster: Rubredoxin-NAD(+) reductase; n=2; Oxalo... 47 0.001
UniRef50_Q895T9 Cluster: NADH oxidase; n=28; Bacteria|Rep: NADH ... 47 0.001
UniRef50_Q7UMA9 Cluster: Probable NADH oxidase; n=3; Planctomyce... 47 0.001
UniRef50_Q1Q9A6 Cluster: FAD-dependent pyridine nucleotide-disul... 47 0.001
UniRef50_A3TFZ7 Cluster: FAD-dependent pyridine nucleotide-disul... 47 0.001
UniRef50_Q7UWN5 Cluster: Nitrite reductase [NAD(P)H] large subun... 46 0.002
UniRef50_Q0SDP4 Cluster: Alkene monooxygenase rubredoxin reducta... 46 0.002
UniRef50_Q0SDC8 Cluster: Probable FAD-dependent oxidoreductase; ... 46 0.002
UniRef50_Q0RVH2 Cluster: Probable ferredoxin--NAD(+) reductase; ... 46 0.002
UniRef50_Q8XLM7 Cluster: Rubredoxin; n=3; Clostridium perfringen... 46 0.002
UniRef50_Q7MXK3 Cluster: Pyridine nucleotide-disulphide oxidored... 46 0.002
UniRef50_Q4FTN7 Cluster: Dihydrolipoamide dehydrogenase; n=2; Ps... 46 0.002
UniRef50_Q2W1P4 Cluster: Uncharacterized NAD(FAD)-dependent dehy... 46 0.002
UniRef50_Q1JFJ8 Cluster: NADH peroxidase; n=12; Streptococcus py... 46 0.002
UniRef50_A4XB07 Cluster: Pyridine nucleotide-disulphide oxidored... 46 0.002
UniRef50_Q3A8Z5 Cluster: Putative nitrate reductase; n=1; Carbox... 46 0.003
UniRef50_A1I9Y1 Cluster: Rhodanese-like; n=4; Deltaproteobacteri... 46 0.003
>UniRef50_Q9NNW7 Cluster: Thioredoxin reductase 2, mitochondrial
precursor; n=63; Coelomata|Rep: Thioredoxin reductase 2,
mitochondrial precursor - Homo sapiens (Human)
Length = 524
Score = 550 bits (1358), Expect = e-155
Identities = 263/450 (58%), Positives = 322/450 (71%), Gaps = 4/450 (0%)
Query: 15 AGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPK 74
AG DYDL V+GGGSGGLACAKEA LG KV V+DYV PSPQGT+WGLGGTCVNVGCIPK
Sbjct: 35 AGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPK 94
Query: 75 KLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKI 134
KLMHQAALLG I +A YGWEV + +W + EAVQNH+KS+NW RV L+++K+
Sbjct: 95 KLMHQAALLGGLIQDAPNYGWEVAQ--PVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKV 152
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPD-IPGAVEYCISSDDIF 193
Y N F D HT+ K G + ++A +I+IA GGRP YP I GA+EY I+SDDIF
Sbjct: 153 KYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIF 212
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKG 253
L PGKTLVVGA Y+ LECAGFL +G T+++RS+PLRGFDQQM+ V M G
Sbjct: 213 WLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHG 272
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
F C P V +L GQL+ W+++ T + FDTVL A GR T++LNLE AGV
Sbjct: 273 TRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGV 332
Query: 314 TCVSNSGKIIAET-EQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
++ KI+ ++ E T+V +IYA+GDV+EG+PELTP+AI AGRLL +R+F G++ MDY
Sbjct: 333 DTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDY 392
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
DNV TTVFTPLEYGCVGLSEE A+ARHG + VEVYHA YKP EF + R+ CY+K V
Sbjct: 393 DNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVC 452
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
LRE PQ +LGLHF+GP AGEV QGFA +K
Sbjct: 453 LREPPQLVLGLHFLGPNAGEVTQGFALGIK 482
>UniRef50_Q99MD6 Cluster: Thioredoxin and glutathione reductase;
n=9; Eukaryota|Rep: Thioredoxin and glutathione
reductase - Mus musculus (Mouse)
Length = 615
Score = 521 bits (1286), Expect = e-146
Identities = 253/449 (56%), Positives = 319/449 (71%), Gaps = 6/449 (1%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+DYDL +IGGGSGGL+CAKEA NLG KV VLD+V PSPQGT WGLGGTCVNVGCIPKKLM
Sbjct: 127 HDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPKKLM 186
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
HQAALLG ++ +A YGWE +K NW A+TEA+Q+HI S+NW RV LREK + YV
Sbjct: 187 HQAALLGHALQDAKKYGWEYNQ--QVKHNWEAMTEAIQSHIGSLNWGYRVTLREKGVTYV 244
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
N GEF D H + AT K G + TA VIA G RP Y I G EYCI+SDD+FSL +
Sbjct: 245 NSFGEFVDLHKIKATNKKGQETFYTASKFVIATGERPRYLGIQGDKEYCITSDDLFSLPY 304
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
PG TLVVGA Y+GLECAGFL LG TV+VRSV LRGFDQ+MA+ V S +EQ+GV F
Sbjct: 305 CPGCTLVVGASYVGLECAGFLAGLGLDVTVMVRSVLLRGFDQEMAEKVGSYLEQQGVKFQ 364
Query: 258 NKCVPLSVEKLE---TGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
K P+ V++LE G+LK ++TE E E +++TVL+A GR + T+ + LE GV
Sbjct: 365 RKFTPILVQQLEKGLPGKLKVVAKSTEGPETVEGIYNTVLLAIGRDSCTRKIGLEKIGVK 424
Query: 315 CVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+GKI + + EQTNV ++YA+GD+L+GKPELTPVAI AG+LLARR+F + + DY
Sbjct: 425 INEKNGKIPVNDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSLEKCDYI 484
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
N+ TTVFTPLEYGC GLSEE A+ + + +EVYH + P E+ + R+ CY K +
Sbjct: 485 NIPTTVFTPLEYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTVAGRDNNTCYAKIICN 544
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ +R++G H +GP AGE+ QGFAAA+K
Sbjct: 545 KFDNERVVGFHLLGPNAGEITQGFAAAMK 573
>UniRef50_Q16881 Cluster: Thioredoxin reductase 1, cytoplasmic
precursor; n=91; Eumetazoa|Rep: Thioredoxin reductase 1,
cytoplasmic precursor - Homo sapiens (Human)
Length = 499
Score = 512 bits (1264), Expect = e-144
Identities = 248/453 (54%), Positives = 321/453 (70%), Gaps = 6/453 (1%)
Query: 14 LAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP 73
L +YDYDL +IGGGSGGLA AKEA G KV VLD+VTP+P GT+WGLGGTCVNVGCIP
Sbjct: 7 LPKSYDYDLIIIGGGSGGLAAAKEAAQYGKKVMVLDFVTPTPLGTRWGLGGTCVNVGCIP 66
Query: 74 KKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK 133
KKLMHQAALLG+++ ++ YGW+V + +K +W + EAVQNHI S+NW RV LREKK
Sbjct: 67 KKLMHQAALLGQALQDSRNYGWKVE--ETVKHDWDRMIEAVQNHIGSLNWGYRVALREKK 124
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIF 193
+ Y N G+F H + AT G +K +A+ +IA G RP Y IPG EYCISSDD+F
Sbjct: 125 VVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEYCISSDDLF 184
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKG 253
SL + PGKTLVVGA Y+ LECAGFL +G TV+VRS+ LRGFDQ MA + ME+ G
Sbjct: 185 SLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHG 244
Query: 254 VVFHNKCVPLSVEKLET---GQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
+ F + VP+ VE++E G+L+ Q+T ++E E ++TV++A GR A T+ + LE
Sbjct: 245 IKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLET 304
Query: 311 AGVTCVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
GV +GKI + + EQTNV IYA+GD+LE K ELTPVAI AGRLLA+R++AG+T
Sbjct: 305 VGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVK 364
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
DY+NV TTVFTPLEYG GLSEE A+ + G + +EVYH+++ P E+ IP R+ CY K
Sbjct: 365 CDYENVPTTVFTPLEYGACGLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAK 424
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + +R++G H +GP AGEV QGFAAA+K
Sbjct: 425 IICNTKDNERVVGFHVLGPNAGEVTQGFAAALK 457
>UniRef50_Q17745 Cluster: Thioredoxin reductase 1; n=6;
Bilateria|Rep: Thioredoxin reductase 1 - Caenorhabditis
elegans
Length = 667
Score = 468 bits (1153), Expect = e-130
Identities = 233/457 (50%), Positives = 306/457 (66%), Gaps = 15/457 (3%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+ YDL VIGGGSGGLA AKEA LG KV LD+V PSPQGT WGLGGTCVNVGCIPKKLM
Sbjct: 171 HTYDLIVIGGGSGGLAAAKEASRLGKKVACLDFVKPSPQGTSWGLGGTCVNVGCIPKKLM 230
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
HQA+LLG SIH+A YGW++P ++ W L ++VQ+HI S+NW RV LREK + Y+
Sbjct: 231 HQASLLGHSIHDAKKYGWKLPE-GKVEHQWNHLRDSVQDHIASLNWGYRVQLREKTVTYI 289
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
N GEF + AT K +++TA +I+ G RP YP+IPG EY I+SDD+F L +
Sbjct: 290 NSYGEFTGPFEISATNKKKKVEKLTADRFLISTGLRPKYPEIPGVKEYTITSDDLFQLPY 349
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
PGKTL VGA Y+ LECAGFL+ G+ TV+VRS+ LRGFDQ MA+ + M G+ F
Sbjct: 350 SPGKTLCVGASYVSLECAGFLHGFGFDVTVMVRSILLRGFDQDMAERIRKHMIAYGMKF- 408
Query: 258 NKCVPLSVEKLE------TGQLKARW--QNTETQERGE--DVFDTVLMATGRYALTKTLN 307
VP +E+++ G+ + W +N ET E E + ++T+LMA GR A+T +
Sbjct: 409 EAGVPTRIEQIDEKTDEKAGKYRVFWPKKNEETGEMQEVSEEYNTILMAIGREAVTDDVG 468
Query: 308 LEAAGVTCVSNSGKIIAETEQ-TNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGA 366
L GV + S K++ EQ T + +YA+GDVLEG PELTPVAI AGR+L RR+F GA
Sbjct: 469 LTTIGVE-RAKSKKVLGRREQSTTIPWVYAIGDVLEGTPELTPVAIQAGRVLMRRIFDGA 527
Query: 367 TQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIR-N 425
+ +YD + TTVFTPLEYGC GLSEE A+ ++G D + +YH + P E+ I +R + +
Sbjct: 528 NELTEYDQIPTTVFTPLEYGCCGLSEEDAMMKYGKDNIIIYHNVFNPLEYTISERMDKDH 587
Query: 426 CYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
CYLK + LR ++++G H + P AGEV QGF A+K
Sbjct: 588 CYLKMICLRNEEEKVVGFHILTPNAGEVTQGFGIALK 624
>UniRef50_P30635 Cluster: Probable glutathione reductase 2; n=2;
Caenorhabditis|Rep: Probable glutathione reductase 2 -
Caenorhabditis elegans
Length = 503
Score = 433 bits (1068), Expect = e-120
Identities = 214/447 (47%), Positives = 301/447 (67%), Gaps = 10/447 (2%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL VIG GSGGL+C+K A +LGA V ++D V P+P G WG+GGTC NVGCIPKKLMHQ
Sbjct: 21 FDLIVIGAGSGGLSCSKRAADLGANVALIDAVEPTPHGHSWGIGGTCANVGCIPKKLMHQ 80
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA++G+ + A YGW + IK +W L++ V + +K+ NW+ RV L +KKI+Y N
Sbjct: 81 AAIVGKELKHADKYGWNGIDQEKIKHDWNVLSKNVNDRVKANNWIYRVQLNQKKINYFNA 140
Query: 140 LGEF--KDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
EF KD + T KN +K ++A N+VI+ G RP YP+IPGA E I+SDD+F+L
Sbjct: 141 YAEFVDKDKIVITGTDKNKTKNFLSAPNVVISTGLRPKYPNIPGA-ELGITSDDLFTLAS 199
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
PGKTL+VG GY+ LECAGFL++ VLVRS+PL+GFD+ V ++ GV
Sbjct: 200 VPGKTLIVGGGYVALECAGFLSAFNQNVEVLVRSIPLKGFDRDCVHFVMEHLKTTGVKVK 259
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ VE++E + ++ + T T G + +DTV+ A GR K+LNL+ AGV
Sbjct: 260 EH---VEVERVEA--VGSKKKVTFTGNGGVEEYDTVIWAAGRVPNLKSLNLDNAGVRTDK 314
Query: 318 NSGKIIA-ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
SGKI+A E ++ + + +YAVGD+++ + ELTP+AI +G+LLA R+F+ + Q + +D VA
Sbjct: 315 RSGKILADEFDRASCNGVYAVGDIVQDRQELTPLAIQSGKLLADRLFSNSKQIVRFDGVA 374
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQ-RNIRNCYLKAVALRE 435
TTVFTPLE VGL+EE A+ +HG D +EV+H+ + P E+ +PQ ++ CY+KAV R+
Sbjct: 375 TTVFTPLELSTVGLTEEEAIQKHGEDSIEVFHSHFTPFEYVVPQNKDSGFCYVKAVCTRD 434
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
Q+ILGLHFVGP A EVIQG+A A +
Sbjct: 435 ESQKILGLHFVGPNAAEVIQGYAVAFR 461
>UniRef50_Q6KG49 Cluster: Mitochondrial thioredoxin reductase 2;
n=7; Eumetazoa|Rep: Mitochondrial thioredoxin reductase
2 - Mus musculus (Mouse)
Length = 496
Score = 427 bits (1052), Expect = e-118
Identities = 208/372 (55%), Positives = 257/372 (69%), Gaps = 4/372 (1%)
Query: 16 GTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK 75
G +DL VIGGGSGGLACAKEA LG KV V DYV PSP+GTKWGLGGTCVNVGCIPKK
Sbjct: 39 GQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKK 98
Query: 76 LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKID 135
LMHQAALLG I +A YGWEV ++ NW + EAVQNH+KS+NW RV L+++K+
Sbjct: 99 LMHQAALLGGMIRDAHHYGWEVAQ--PVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVK 156
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFS 194
Y N F D HT+ K G ++A++IVIA GGRP YP + GA+EY I+SDDIF
Sbjct: 157 YFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFW 216
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGV 254
L PGKTLVVGA Y+ LECAGFL +G TV++RS+PLRGFDQQM+ VT ME G
Sbjct: 217 LKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHGT 276
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
F CVP ++KL T QL+ W++ + + FDTVL A GR T+TLNLE AG++
Sbjct: 277 QFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGIS 336
Query: 315 CVSNSGKIIAET-EQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ KII + E T+V +IYA+GDV EG+PELTP AI AG+LLA+R+F ++ MDY
Sbjct: 337 TNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYS 396
Query: 374 NVATTVFTPLEY 385
NV + PLE+
Sbjct: 397 NVYHAYYKPLEF 408
Score = 83.0 bits (196), Expect = 2e-14
Identities = 35/61 (57%), Positives = 43/61 (70%)
Query: 402 DKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
D VYHA+YKP EF + R+ CY+K V +RE PQ +LGLHF+GP AGEV QGFA +
Sbjct: 394 DYSNVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGI 453
Query: 462 K 462
K
Sbjct: 454 K 454
>UniRef50_Q25861 Cluster: Thioredoxin reductase; n=14;
Apicomplexa|Rep: Thioredoxin reductase - Plasmodium
falciparum (isolate FCH-5)
Length = 541
Score = 409 bits (1006), Expect = e-112
Identities = 221/465 (47%), Positives = 288/465 (61%), Gaps = 28/465 (6%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
TYDYD VIGGG GG+A AKEA GA+V + DYV PS QGTKWG+GGTCVNVGC+PKKL
Sbjct: 39 TYDYDYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKL 98
Query: 77 MHQAALLGESIH-EAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKID 135
MH A +G ++ AYGW+ D +K +W L VQ+HI+S+N+ LR K+
Sbjct: 99 MHYAGHMGSIFKLDSKAYGWK---FDNLKHDWKKLVTTVQSHIRSLNFSYMTGLRSSKVK 155
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKE--ITAKNIVIAVGGRPHYPD-IPGAVEYCISSDDI 192
Y+NGL + KD +T+ LK KE +T K I+IA G RPH PD + GA E I+SDDI
Sbjct: 156 YINGLAKLKDKNTVSYYLKGDLSKEETVTGKYILIATGCRPHIPDDVEGAKELSITSDDI 215
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQK 252
FSL PGKTLVVGA Y+ LEC+GFLNSLGY TV VRS+ LRGFDQQ A V ME++
Sbjct: 216 FSLKKDPGKTLVVGASYVALECSGFLNSLGYDVTVAVRSIVLRGFDQQCAVKVKLYMEEQ 275
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
GV+F N +P + K++ L E ++ +++DTVL A GR LNLE+
Sbjct: 276 GVMFKNGILPKKLTKMDDKIL------VEFSDKTSELYDTVLYAIGRKGDIDGLNLESLN 329
Query: 313 VTCVSNSGKIIAE-TEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
+ ++ KIIA+ TN+ +I+AVGDV E PEL PVAI AG +LARR+F + + MD
Sbjct: 330 MNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILARRLFKDSDEIMD 389
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFI--PQRNIR----- 424
Y + T+++TP+EYG G SEE A +G VEV+ + E Q++IR
Sbjct: 390 YSYIPTSIYTPIEYGACGYSEEKAYELYGKSNVEVFLQEFNNLEISAVHRQKHIRAQKDE 449
Query: 425 -------NCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
C K V L+ R++G H+VGP AGEV QG A A++
Sbjct: 450 YDLDVSSTCLAKLVCLKNEDNRVIGFHYVGPNAGEVTQGMALALR 494
>UniRef50_A0E909 Cluster: Chromosome undetermined scaffold_83, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_83,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 475
Score = 407 bits (1002), Expect = e-112
Identities = 212/452 (46%), Positives = 285/452 (63%), Gaps = 17/452 (3%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
Y YD+ VIGGGSGGL EA LG +V + DY+ PSP GT+WG GGTC NVGCIPKKLM
Sbjct: 5 YQYDIFVIGGGSGGLTVVDEAQRLGKRVGLADYIKPSPHGTQWGTGGTCPNVGCIPKKLM 64
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVN-----WVTRVDLREK 132
H AL+GE HE A GW+ + K +W L VQ +K +N W+ +
Sbjct: 65 HMTALIGEIRHELTATGWQGVDPHS-KNDWNILVNEVQRQVKGINKGNDDWL----IATN 119
Query: 133 KIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDD 191
I Y N LG+ KD HT+ K+G + +TA+ IVIAVG RP +P DIP + I+SDD
Sbjct: 120 GITYYNKLGKLKDDHTIELIDKDGQSEFVTAEYIVIAVGSRPSFPTDIPNVKQLTITSDD 179
Query: 192 IFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQ 251
+FSL PGKTLVVGA Y+ LECAGFL LGY TV+VRS+ LRGFDQ+MA+ + M+
Sbjct: 180 LFSLKKAPGKTLVVGASYVALECAGFLTGLGYDVTVMVRSILLRGFDQEMAERIGEFMKI 239
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
G F +P S+E ++ G+ +W QE+ E VFDTVL+A GR A T+ L LE
Sbjct: 240 HGTKFIRGTIPSSIEDVD-GKRLVKWV-LNGQEQSE-VFDTVLLAIGRSADTQNLGLEQV 296
Query: 312 GVTCVSNSGKIIA-ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
GV SGKIIA + + T+V NI+A+GD ++G+ ELTP AI G+ L +R+++ Q M
Sbjct: 297 GVQTNKESGKIIANDADSTSVPNIFAIGDCVQGRLELTPTAIMCGKRLIKRLYSNGNQIM 356
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
+Y +V+TTVFTPLEYGCVG SEE A+ + G D ++++ + + P + R CY K
Sbjct: 357 EYSDVSTTVFTPLEYGCVGYSEEAAIQKFGKDNLKIFTSEFTPLFWNFANRK-GTCYAKL 415
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ +++ ++G H++GP A EV QGF +K
Sbjct: 416 I-VKKDDDVVIGFHYLGPDAAEVTQGFGVVIK 446
>UniRef50_Q8H6T2 Cluster: Thioredoxin reductase TR1; n=1;
Chlamydomonas reinhardtii|Rep: Thioredoxin reductase TR1
- Chlamydomonas reinhardtii
Length = 533
Score = 387 bits (952), Expect = e-106
Identities = 188/330 (56%), Positives = 230/330 (69%), Gaps = 3/330 (0%)
Query: 15 AGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPK 74
A Y+YDL VIGGGSGGLACAKEA LG KV +LDYV PSP GT WGLGGTCVNVGCIPK
Sbjct: 11 ASAYEYDLVVIGGGSGGLACAKEAAKLGKKVCLLDYVVPSPAGTSWGLGGTCVNVGCIPK 70
Query: 75 KLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKI 134
KLMH A LLGE +A YGW++P + I++NW L VQNHI S+NW RV LRE +
Sbjct: 71 KLMHNAGLLGEGFSDARGYGWKLP--EKIEMNWEDLVMGVQNHIGSLNWGYRVALREASV 128
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFS 194
Y+N G F DAHT+ A +NG+K +TA+ +VIAVGGRP Y +PG E CI+SDDIFS
Sbjct: 129 KYLNAKGSFVDAHTVEAVERNGTKHTLTAERVVIAVGGRPKYLGVPGDKELCITSDDIFS 188
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGV 254
PPGKTLVVGA YI LECAGFL +LGY V+ RS+ LRGFDQ++A+ + +ME++GV
Sbjct: 189 RATPPGKTLVVGASYIALECAGFLRALGYEVAVMARSIFLRGFDQEIAELIGKDMERRGV 248
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
VP + E+ + Q+K ++N + + FDTVL+A GR A T L LE GVT
Sbjct: 249 RMIKPAVPTAFER-DGEQIKCTFKNLDFGVEMSESFDTVLLAVGRDACTFDLGLEKVGVT 307
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGK 344
+SGKI EQTNV +IYA+GDVLE +
Sbjct: 308 YDKSSGKIPVTAEQTNVPSIYAIGDVLESR 337
>UniRef50_UPI0000F2E9A5 Cluster: PREDICTED: similar to extracellular
reelin; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to extracellular reelin - Monodelphis domestica
Length = 503
Score = 384 bits (946), Expect = e-105
Identities = 201/418 (48%), Positives = 257/418 (61%), Gaps = 11/418 (2%)
Query: 54 SPQGTKWGLGGTCVNVGCIPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEA 113
+P GT WGLGGTCVNVGCIPKKLMH AALLG ++ +A YGW+V + + NW + E
Sbjct: 48 TPDGTSWGLGGTCVNVGCIPKKLMHYAALLGGALGDARHYGWDVAPPE--QHNWTYMAEG 105
Query: 114 VQNHIKSVNWVTRVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGR 173
+QNHIKS+NW RV L+++KI Y+N G F D H + + K G + +I A++I++A G R
Sbjct: 106 IQNHIKSLNWGHRVQLQDRKIRYLNAQGSFLDEHVVRSVTKAGKEIDIMAEHIMVARGAR 165
Query: 174 PHYPDIPGAVEY--CISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRS 231
P P A ++ + + LVVGA Y+ LECAGFL G TV++RS
Sbjct: 166 PALQPSPRASDHEGRLEPRVPWLKRCLFLSRLVVGASYVALECAGFLTGFGLDTTVMMRS 225
Query: 232 VPLRGFDQQMAQAVTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFD 291
+PLRGFDQQMA VT ME G F KC+ +EKL+ Q++ W+N E + FD
Sbjct: 226 IPLRGFDQQMAHLVTDYMESHGTKFLKKCIVKKLEKLKDNQIQVTWENRELDKEEMGTFD 285
Query: 292 TVLMATGRYALTKTLNLEAAGVTCVSNSGKIIAET-EQTNVSNIYAVGDVLEGK-PELTP 349
TVL A GR T LNLE GV + KI+ + E T+V +IYA+GD+ + + P TP
Sbjct: 286 TVLWAIGRVPETSNLNLEKVGVELHPTTQKIVVDAKEMTSVPHIYAIGDISQVRTPPATP 345
Query: 350 VAIHAGRL-----LARRMFAGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKV 404
AG+L + R F V TTVFTPLEY CVGLSEE A RHG D +
Sbjct: 346 GRAAAGKLDGDCPRSGRCFGRPCAGSVISQVPTTVFTPLEYACVGLSEEEAEQRHGLDHI 405
Query: 405 EVYHAFYKPTEFFIPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
EVYHA+YKP EF + +R+ CY+K V LRE QRILGLHFVGP AGEVIQGFA ++
Sbjct: 406 EVYHAYYKPLEFTVTERDASQCYIKMVCLREKDQRILGLHFVGPNAGEVIQGFALGIR 463
>UniRef50_A0C460 Cluster: Chromosome undetermined scaffold_148,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_148,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 524
Score = 374 bits (921), Expect = e-102
Identities = 214/472 (45%), Positives = 287/472 (60%), Gaps = 34/472 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+AVIGGGSGGLA A E LG K+ V DYVTPS QG+ WGLGGTCVNVGCIPKKLMH
Sbjct: 18 FDVAVIGGGSGGLAFALEGAKLGLKIAVFDYVTPSSQGSIWGLGGTCVNVGCIPKKLMHH 77
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+ALL E+ + YGW PS + ++NW L E VQNHIK +N+ + +L++ I Y+N
Sbjct: 78 SALLKENNEGSTPYGW-TPS-EQEQVNWDVLVENVQNHIKGLNYGYKGNLQKSGILYLNE 135
Query: 140 LGEFKDAHTLI------ATLKNGSK-KEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDI 192
L FKD HTL+ K+ +K +E+ K VI+ GGRP + ++ I+SDDI
Sbjct: 136 LATFKDNHTLLYGKLDDFKSKDENKLRELKFKYCVISTGGRP--TKLQSIEKHAITSDDI 193
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQ- 251
FS PPGKTLVVG GYI LECAG L LGY T++ R LR FDQ + + + ++
Sbjct: 194 FSQQKPPGKTLVVGGGYIALECAGMLKGLGYDVTLMTRGKYLREFDQDVVKMILDHYQKY 253
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
V + +P E+ + ++ +W++T + FDTVLMA GR A T+ LNL+
Sbjct: 254 LRVNIVPESLPFHSEQ-KDDKILVKWRSTVNSQEDGGAFDTVLMAIGRQANTQMLNLDKV 312
Query: 312 GVTCVSNSGKIIA----ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARR---MFA 364
G+ N+ KI A E E+T V NI+A+GDVL G PELTPVA +G+LLA+R +
Sbjct: 313 GIKVNPNNNKIFANYNGEAERTEVDNIFAIGDVLNGIPELTPVASKSGQLLAKRIQLLIK 372
Query: 365 GATQPMDYDNV-------ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFF 417
G+ +Y+N TTVFTPLEY VGLSEE A + G +E+YH+ + P E
Sbjct: 373 GSYSKQEYENTKLEYNDYPTTVFTPLEYSFVGLSEEQAKQKFGEHDIEIYHSKFVPLEEQ 432
Query: 418 IPQR---NI----RNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + N R Y+KA+ +++GLH++GP AGEV+QGF AVK
Sbjct: 433 LCDKLDENYELMQRKVYVKAICHVSDNNKVVGLHYLGPNAGEVMQGFGVAVK 484
>UniRef50_Q4UCW3 Cluster: Thioredoxin reductase, putative; n=3;
Piroplasmida|Rep: Thioredoxin reductase, putative -
Theileria annulata
Length = 604
Score = 363 bits (894), Expect = 4e-99
Identities = 194/451 (43%), Positives = 269/451 (59%), Gaps = 24/451 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL V+GGG G+A AKEA LG + + DYVTPS +GT WG+GGTCVNVGCIPKKLMH
Sbjct: 115 YDLIVLGGGPAGMAAAKEASRLGKRTVLFDYVTPSARGTSWGVGGTCVNVGCIPKKLMHY 174
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A+LL S ++ YG + + INW L + +QN+IK +N+ R L +DY+N
Sbjct: 175 ASLLRSSNYDKFQYGL-TNTQELTPINWNKLIQTIQNYIKMLNFSYRSSLLTSGVDYINA 233
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFSLGHP 198
G K + +I N K ++ I+IA+G RP+ P D+ GA EY I+SDD+F L
Sbjct: 234 FGILKH-NKIIEYNLNNEIKYVSGDKIIIAIGERPYIPSDVEGANEYAITSDDLFQLNTN 292
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFHN 258
PGKTL+VGA Y+ LECAGFL LGY V VRS+ LRGFD+Q + V ME GV+F
Sbjct: 293 PGKTLIVGASYVALECAGFLTGLGYNVDVSVRSILLRGFDRQCVKKVEELMEASGVLFLY 352
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+P+ +EK QLK + ++ + +DTVL A GR T +L+ G+ N
Sbjct: 353 HKLPIKIEK-HNQQLKVTF-----NDQSVNYYDTVLYAIGRIPSQYTQHLKEVGIEFDGN 406
Query: 319 SGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVATT 378
G I+ E+TN+ +IYAVGD++ P+L PVAI + LL +R+++ M+Y+NV
Sbjct: 407 -GNILVTNEETNIKDIYAVGDIVSKVPKLAPVAIKSSELLIQRLYSNNNTQMNYENVPKC 465
Query: 379 VFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIR-----------NCY 427
V+TP EY GL+EE A+ ++G D +E+Y Y E P I C
Sbjct: 466 VYTPFEYSSCGLTEEEAIEKYGEDNLEIYLKEYNNLE-ISPVHRINKKTNDEFDYPMTCL 524
Query: 428 LKAVALREAPQRILGLHFVGPVAGEVIQGFA 458
K + L++ +I+G+HFVGP AGE++QGF+
Sbjct: 525 SKVICLKDG--KIIGMHFVGPNAGEIMQGFS 553
>UniRef50_UPI000150AB3A Cluster: Pyridine nucleotide-disulphide
oxidoreductase family protein; n=1; Tetrahymena
thermophila SB210|Rep: Pyridine nucleotide-disulphide
oxidoreductase family protein - Tetrahymena thermophila
SB210
Length = 588
Score = 359 bits (884), Expect = 7e-98
Identities = 216/493 (43%), Positives = 290/493 (58%), Gaps = 50/493 (10%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+A+IGGGSGGLA A EA LG K V D+V S QG WGLGGTCVNVGCIPKKLMH
Sbjct: 56 YDVAIIGGGSGGLAFAFEAQKLGMKAVVFDFVEESTQGNSWGLGGTCVNVGCIPKKLMHT 115
Query: 80 AALLGESIHEAVAYGWEVPSLDAIK------INWPALTEAVQNHIKSVNWVTRVDLREKK 133
AAL E I + YG+++ + + + W L VQ++IKS+N+ + L E
Sbjct: 116 AALYKEVILNSSGYGFDLEGKNLEEKYKQEYLVWQHLVNNVQSYIKSINFGYKKSLGELN 175
Query: 134 IDYVNGLGEFKDAHTLIATLK----------NGSKKE-------ITAKNIVIAVGGRPHY 176
IDYVN F D +TL+ + K N S K +TA IV+AVGGRP
Sbjct: 176 IDYVNAFASFYDKNTLVFSPKVDAISGFLKDNESYKANTEQLGYVTADKIVVAVGGRPQL 235
Query: 177 ---PDIPGAVEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP 233
+ +Y I+SDDIF PPGKTLV+G GYI LEC+GFL++LGY T++ RS+
Sbjct: 236 LSDSQCQNSNKYAITSDDIFMQKKPPGKTLVIGGGYIALECSGFLSTLGYDTTMMTRSLY 295
Query: 234 LRGFDQQMAQAVTSEME-QKGVVFHNKCVPLSVEKLETGQLKARWQNTETQER-GEDVFD 291
LR FDQ +A+ + ++ V +P+S+EK++ LK + QN E + + ED F+
Sbjct: 296 LREFDQDIAKMILENIQTHSKVKVVPTSLPVSLEKVDEDTLKVKIQNQEDKSKIYEDTFN 355
Query: 292 TVLMATGRYALTKTLNLEAAGVTCVSNSGKIIA----ETEQTNVSNIYAVGDVLEGKPEL 347
TVLMA GR T+ LNLE GV + KI E EQT+V IYA+GDVL+G PEL
Sbjct: 356 TVLMAIGRKPNTQKLNLEKVGVQLNQKNKKIQGRFNDELEQTSVEGIYALGDVLDGVPEL 415
Query: 348 TPVAIHAGRLLARRM--FAGATQP---------MDYDNVATTVFTPLEYGCVGLSEETAL 396
TPVA G+LLARR+ +P MDY++ TTVFTP+EY C G SE+ A+
Sbjct: 416 TPVAQKQGQLLARRIQHKKENKEPNTVFIQKNSMDYNDFPTTVFTPVEYSCAGYSEKQAV 475
Query: 397 ARHGADKVEVYHAFYKPTEFFIPQR---NI----RNCYLKAVALREAPQRILGLHFVGPV 449
+ G + +EVYH+ + P E + R N R Y K + + +R++G+H++GP
Sbjct: 476 EKFGEENIEVYHSKFTPLEEQLSPRVDENFDTIYRKAYAKVICNKLDNERVVGIHYLGPN 535
Query: 450 AGEVIQGFAAAVK 462
AGEV+QG+ A+K
Sbjct: 536 AGEVMQGYGVAMK 548
>UniRef50_A0CQA5 Cluster: Chromosome undetermined scaffold_24, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_24,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 443
Score = 340 bits (836), Expect = 4e-92
Identities = 183/428 (42%), Positives = 257/428 (60%), Gaps = 10/428 (2%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIGGG+GGLA +K + LG KV + DY TPSP T WG GGTCVNVGC+P KLM
Sbjct: 7 YDLFVIGGGAGGLASSKASALLGKKVGIADYATPSPHATTWGTGGTCVNVGCVPTKLMPF 66
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A +GE + +A G++ + K NW L E VQ HIK +N L++ IDY N
Sbjct: 67 SAKMGEIRKDQIAAGYQGVESEG-KHNWKQLIETVQKHIKELNVRQESSLKDHGIDYYNK 125
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
+F D HT+ T G K+ I+AKNI++ VG RP P V I+S+D+F PP
Sbjct: 126 FAKFIDRHTIELTDVKGEKEIISAKNIIVCVGSRPMLYQDPKLV---ITSEDVFQQTTPP 182
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFHNK 259
GKTLV+GA Y+GLECAGF++ G+ TVLVR+ +R FDQ+MA V M G+ F +
Sbjct: 183 GKTLVIGASYVGLECAGFIHGFGFDTTVLVRTRVMRNFDQEMASKVEGYMSDGGIKFVKR 242
Query: 260 CVPLSVEKLETGQLK-ARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+ S+ ++ G+ + +W E ED++DTVL GR A TK LNLE+ GV +
Sbjct: 243 ALLQSISAVDNGKRRLVKWVRDGVVE--EDIYDTVLYGIGRQASTKQLNLESIGVKIDAR 300
Query: 319 SGKIIA-ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
+ KI+A E ++T V NIY +GD + E TP+ + GR L +RM+ + + MDYD+V T
Sbjct: 301 NYKIMADEYDRTTVDNIYEIGDCCLKRQEYTPIEVMDGRKLDKRMYGDSNEIMDYDDVDT 360
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQR-NIRNCYLKAVALREA 436
+ T +EYG +GL EE A ++G D ++ K ++ I QR + + C K + +E+
Sbjct: 361 NIQTTIEYGSIGLQEERAKKKYGDDGKKIKRTKTKTKKWRIRQRDDEKYCGGKLIVHKES 420
Query: 437 PQRILGLH 444
+RI+G H
Sbjct: 421 -ERIIGYH 427
>UniRef50_UPI00006CFB8B Cluster: Pyridine nucleotide-disulphide
oxidoreductase family protein; n=1; Tetrahymena
thermophila SB210|Rep: Pyridine nucleotide-disulphide
oxidoreductase family protein - Tetrahymena thermophila
SB210
Length = 638
Score = 333 bits (819), Expect = 5e-90
Identities = 203/494 (41%), Positives = 283/494 (57%), Gaps = 52/494 (10%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+A+IGGGS GL+ A EA LG K + ++V P+ +G KWGLGGTCVNVGCIPKKL H
Sbjct: 106 YDVAIIGGGSAGLSFALEAHKLGMKTILFNFVEPTFRGNKWGLGGTCVNVGCIPKKLFHT 165
Query: 80 AALLGESIHEAVAYGW---------------EVPSLDAIKINWPALTEAVQNHIKSVNWV 124
A+++ +S+ ++ +G+ E + + W L VQN+I +N
Sbjct: 166 ASIIKDSLLKSADFGFGGDRQQFQIDLDHNNEPKNKQLLNFRWRQLVSNVQNYISDLNLG 225
Query: 125 TRVDLREKKIDYVNGLGEFKDAHTLIATL-----------KNGSK---KEITAKNIVIAV 170
L + I YVN L D +T+ T ++ SK ++I A IVIAV
Sbjct: 226 FEAQLINRSIPYVNALATLGDKNTIYYTTNKYDLYDAIQRRDFSKLISQQIKADYIVIAV 285
Query: 171 GGRPHY-PDIPGAVEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV 229
GGRP Y + + +Y I+SDDIFSL +PPGKTLV+G+GYI E AGFL++LG T++
Sbjct: 286 GGRPKYIKECENSEKYSITSDDIFSLKNPPGKTLVLGSGYIAFESAGFLSNLGMNTTLMA 345
Query: 230 RSVPLRGFDQQMAQAVTSEMEQ-KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGED 288
R LR FDQ +AQ + +M+Q GV F VP +EK + + +++ + + D
Sbjct: 346 RGQYLREFDQDIAQMIVEDMKQFNGVRFIQHSVPYKIEKDDKDYVVC-YKSIKNNDEQCD 404
Query: 289 VFDTVLMATGRYALTKTLNLEAAGVTCVSNSGKIIA----ETEQTNVSNIYAVGDVLEGK 344
F TVL A GR LNL+ GV S + KII ++E+T+V NI++VGDVL G
Sbjct: 405 KFQTVLQAVGRQPNVSLLNLDQIGVQVHSETKKIIGGYNEDSERTSVDNIFSVGDVLHGV 464
Query: 345 PELTPVAIHAGRLLARRMFA---------GATQPMDYDNVATTVFTPLEYGCVGLSEETA 395
PEL P+A +G+LLA R+F MDY+ + TT+FTP EY VGL+EE A
Sbjct: 465 PELNPIAQMSGKLLAHRIFGLKMNDNMKYYNRHKMDYNCIPTTLFTPQEYSFVGLNEEQA 524
Query: 396 LARHGADKVEVYHAFYKPTE-----FFIPQRNI--RNCYLKAVALREAPQRILGLHFVGP 448
L ++G D+VE+YH+ + P E + Q NI R Y K + + RILG+H+ GP
Sbjct: 525 LQQYGKDRVEIYHSRFTPLEEQLTFSYDDQGNIIKRKSYCKLICDKFDNNRILGMHYFGP 584
Query: 449 VAGEVIQGFAAAVK 462
AGEV+QG+A A K
Sbjct: 585 NAGEVMQGYAVAFK 598
>UniRef50_Q4SQZ1 Cluster: Chromosome 11 SCAF14528, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 11
SCAF14528, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 629
Score = 302 bits (741), Expect = 1e-80
Identities = 143/248 (57%), Positives = 172/248 (69%), Gaps = 2/248 (0%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
YDYDL VIGGGSGGLAC+KEA LG KV VLDYV P+P+GT WGLGGTCVNVGCIPKKLM
Sbjct: 114 YDYDLIVIGGGSGGLACSKEAALLGKKVMVLDYVVPTPKGTSWGLGGTCVNVGCIPKKLM 173
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
HQ ALL +I +A +GWE +A+ NW + A+ ++I S+NW RV LR+K ++YV
Sbjct: 174 HQTALLRTAIQDARKFGWEFD--EAVTHNWETMKTAINDYIGSLNWGYRVSLRDKNVNYV 231
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
N EF D H + AT K G + TA V+A G RP Y +PG EYCI+SDD+FSL +
Sbjct: 232 NAYAEFVDPHKIKATNKRGKETFYTAARFVLATGERPRYLGVPGDKEYCITSDDLFSLPY 291
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
PGKTLV+GA Y+ LEC GFL LG TV+VRS+ LRGFDQ MA ME+ GV F
Sbjct: 292 CPGKTLVIGASYVALECGGFLAGLGLDVTVMVRSILLRGFDQDMANRAGQYMEEHGVKFL 351
Query: 258 NKCVPLSV 265
K VP+ V
Sbjct: 352 RKYVPVQV 359
>UniRef50_Q4UWG8 Cluster: Reductase; n=10; Gammaproteobacteria|Rep:
Reductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 456
Score = 265 bits (650), Expect = 1e-69
Identities = 176/452 (38%), Positives = 244/452 (53%), Gaps = 25/452 (5%)
Query: 14 LAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP 73
++ YDYD+ V+GGGSGGLA A A GA+V +++ P LGGTCVN+GC+P
Sbjct: 1 MSARYDYDVVVLGGGSGGLAAAFRAAKHGARVAIME---PGE------LGGTCVNLGCVP 51
Query: 74 KKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK 133
KK M AA L I A A G++V + W L Q +I +++ R L +
Sbjct: 52 KKAMWLAADLASKIELAGALGFDVVRPT---LTWQELVTHRQGYIGNIHASYRRRLDDDG 108
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIF 193
+ + G +D HTL+ +TA++IVIA G P P + GA E+ SDD F
Sbjct: 109 VVLIPQRGVLQDRHTLMGA----DGVPVTAEHIVIATGAHPLRPHVEGA-EHGHVSDDFF 163
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPL-RGFDQQMAQAVTSEMEQK 252
+L H P +VG GYI +E AG L +LG + V+ L FD ++ + +
Sbjct: 164 NLCHAPDHVAIVGGGYIAVEIAGLLQALGSRVHLFVQGERLLERFDAELTLQLADNLRHL 223
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
GV H V++ +TG+L+ R + E G DVFD V A GR A T L LEA G
Sbjct: 224 GVRLHFGFRTTGVQRDDTGKLRMRGHSAHPGELGNDVFDQVFFAIGRLANTAGLGLEALG 283
Query: 313 VTCVSNSGKIIAETEQT-NVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP-M 370
V + G+I+ + QT NV NI+AVGDV +GK LTPVAI AGR L R+F G M
Sbjct: 284 VE-LGKKGEIVVDDGQTTNVPNIHAVGDV-DGKVGLTPVAIAAGRKLMDRLFGGQPDARM 341
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
DYDNV + VF+ G VGL+EE A R+ V VY + ++P + R+ + K
Sbjct: 342 DYDNVPSVVFSHPPLGAVGLTEEQARERYDG-AVRVYRSNFRPMLHALADAPQRSVF-KL 399
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
V + E +R++G+H +G A E++QGFA AVK
Sbjct: 400 VCVGE-EERVVGVHLLGESADEMLQGFAVAVK 430
>UniRef50_Q58E89 Cluster: MGC84926 protein; n=7; cellular
organisms|Rep: MGC84926 protein - Xenopus laevis
(African clawed frog)
Length = 476
Score = 260 bits (637), Expect = 6e-68
Identities = 166/452 (36%), Positives = 248/452 (54%), Gaps = 29/452 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD V+GGGSGGLA A+ A LGA+ V++ +K LGGTCVNVGC+PKK+M
Sbjct: 19 YDYLVVGGGSGGLASARRAAELGARTAVVE-------SSK--LGGTCVNVGCVPKKIMWN 69
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA+ E IH+ YG+E+P +K W + E ++ +N + + +L++ +I+ + G
Sbjct: 70 AAMHSEYIHDHADYGFEIPD---VKFTWKVIKEKRDAYVSRLNDIYQNNLQKAQIEIIRG 126
Query: 140 LGEF-KDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP---DIPGAVEYCISSDDIFSL 195
F D + NG K +A +I+IA GG+P P ++PGA I+SD F L
Sbjct: 127 NANFTSDPEPTVEV--NGQK--YSAPHILIATGGKPSMPSDAELPGA-SLGITSDGFFEL 181
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGV 254
P +++VVGAGYI +E AG L++LG A++L+R LR FD ++ T E+E GV
Sbjct: 182 TDLPRRSIVVGAGYIAVEIAGILSALGSKASLLIRQDKVLRTFDSIISSNCTEELENAGV 241
Query: 255 VFHNKCVPLSVEKLETG---QLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
SV+K TG ++ + R D +L A GR T+ L LE
Sbjct: 242 EVWKYAQVKSVKKSTTGLEINVQCSMPGRKPTVRTIQDVDCLLWAIGRDPNTEYLGLENL 301
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG-ATQPM 370
G+ ++ E + T+ +YAVGDV G+ LTPVAI AGR L+ R+F G +
Sbjct: 302 GLELDEKGHIVVDEFQNTSRKGVYAVGDVC-GRALLTPVAIAAGRKLSHRLFEGQEDSKL 360
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
DY+N+ T VF+ G VGL+EE A+ G + V+VY + P + +R + C +K
Sbjct: 361 DYNNIPTVVFSHPPIGTVGLTEEEAVTAKGRENVKVYTTSFSPMYHVVTRRKTK-CVMKL 419
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
V + + ++++GLH G E++QGFA A+K
Sbjct: 420 VCVGK-EEKVVGLHMQGLGCDEMLQGFAVAIK 450
>UniRef50_P00390 Cluster: Glutathione reductase, mitochondrial
precursor; n=203; cellular organisms|Rep: Glutathione
reductase, mitochondrial precursor - Homo sapiens
(Human)
Length = 522
Score = 254 bits (623), Expect = 3e-66
Identities = 169/453 (37%), Positives = 241/453 (53%), Gaps = 31/453 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD VIGGGSGGLA A+ A LGA+ V++ LGGTCVNVGC+PKK+M
Sbjct: 65 YDYLVIGGGSGGLASARRAAELGARAAVVE---------SHKLGGTCVNVGCVPKKVMWN 115
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A+ E +H+ YG+ PS + K NW + E ++ +N + + +L + I+ + G
Sbjct: 116 TAVHSEFMHDHADYGF--PSCEG-KFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRG 172
Query: 140 LGEF-KDAHTLIATLKNGSKKEITAKNIVIAVGGRP---HYPDIPGAVEYCISSDDIFSL 195
F D I S K+ TA +I+IA GG P H IPGA I+SD F L
Sbjct: 173 HAAFTSDPKPTIEV----SGKKYTAPHILIATGGMPSTPHESQIPGA-SLGITSDGFFQL 227
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGV 254
PG++++VGAGYI +E AG L++LG ++++R LR FD ++ T E+E GV
Sbjct: 228 EELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGV 287
Query: 255 ----VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
K V ++ LE + A DV D +L A GR TK L+L
Sbjct: 288 EVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPDV-DCLLWAIGRVPNTKDLSLNK 346
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFA-GATQP 369
G+ I+ E + TNV IYAVGDV GK LTPVAI AGR LA R+F
Sbjct: 347 LGIQTDDKGHIIVDEFQNTNVKGIYAVGDVC-GKALLTPVAIAAGRKLAHRLFEYKEDSK 405
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
+DY+N+ T VF+ G VGL+E+ A+ ++G + V+ Y + P + +R + C +K
Sbjct: 406 LDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTK-CVMK 464
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
V + ++++G+H G E++QGFA AVK
Sbjct: 465 MVCANK-EEKVVGIHMQGLGCDEMLQGFAVAVK 496
>UniRef50_Q60151 Cluster: Glutathione reductase; n=31; Bacteria|Rep:
Glutathione reductase - Streptococcus thermophilus
Length = 450
Score = 251 bits (615), Expect = 3e-65
Identities = 167/447 (37%), Positives = 237/447 (53%), Gaps = 29/447 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD VIGGGSGG+A A A GAKV + + G + +GGTCVNVGC+PKK+M
Sbjct: 4 EYDYIVIGGGSGGIASANRAAMHGAKVILFE-------GKE--VGGTCVNVGCVPKKVMW 54
Query: 79 QAALLGESIHE-AVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
A + E++H A YG++V + ++ L Q +I ++ ++ V
Sbjct: 55 YGAQVAETLHRYAGEYGFDVTINN---FDFATLKANRQAYIDRIHGSFERGFDSNGVERV 111
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
F D HT+ + + TA +I+IA GG P YP+IPG+ EY I+SD F L
Sbjct: 112 YEYARFVDPHTVEV-----AGELYTAPHILIATGGHPLYPNIPGS-EYGITSDGFFELDE 165
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGVVF 256
P +T V+GAGYI +E AG LN+LG + VR PLR FD+ + + EM + G
Sbjct: 166 VPKRTAVIGAGYIAVEVAGVLNALGSDTHLFVRKDRPLRTFDKDIIDVLVDEMAKSGPTL 225
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
H V K L + N ET D ++ A GR A T LE GV
Sbjct: 226 HMHANATEVVKNADDSLTISFDNEET-----ITVDCLIWAVGRAANTSGFGLEKTGVELT 280
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQ-PMDYDNV 375
E E T+V IYA+GDV GK +LTPVA+ AGR L+ R+F +DY +V
Sbjct: 281 ERGNIYSDEFENTSVPGIYALGDV-TGKLDLTPVAVKAGRQLSERLFNNKVDAKLDYTDV 339
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
AT VF+ G +GL+EE A+A++GA+ ++VY + + P + N + +K V L E
Sbjct: 340 ATVVFSHPAIGAIGLTEEKAIAKYGAENIKVYKSSFTPMYTALGD-NRQLSTMKLVTLGE 398
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
++I+GLH +G E+IQGF+ A+K
Sbjct: 399 -DEKIIGLHGIGYGVDEMIQGFSVAIK 424
>UniRef50_Q8DIH9 Cluster: Glutathione reductase; n=16;
Cyanobacteria|Rep: Glutathione reductase - Synechococcus
elongatus (Thermosynechococcus elongatus)
Length = 461
Score = 250 bits (613), Expect = 4e-65
Identities = 163/452 (36%), Positives = 236/452 (52%), Gaps = 24/452 (5%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
TYDYDL VIG GSGGLA +K A + GA+V + + G K +GGTCV GC+PKKL
Sbjct: 2 TYDYDLFVIGAGSGGLAASKRAASYGARVAIAE-------GDK--VGGTCVIRGCVPKKL 52
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
M + +AV YGW K+NW L AV + ++ + L + ++
Sbjct: 53 MVYGSKFSHLFEDAVGYGWHPVKA---KLNWERLIRAVDQEVNRLSQLHISYLEKAGVEL 109
Query: 137 VNGLGEFKDAHTLIATLKNGSKK-EITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSL 195
+ F D HTL + G + +TA I+IAVGG P++PG +E+ I+S ++F L
Sbjct: 110 LPFFARFADPHTLELVDRQGQVQGRVTAAKILIAVGGEAIKPNVPG-IEHSITSREMFLL 168
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGV 254
P + ++G GYI +E AG + LG +R PLRGFDQ + V M + G+
Sbjct: 169 PKQPKRLAILGGGYISVEFAGIMQGLGTEVIHFLRGDRPLRGFDQDIQDGVYGGMIRHGI 228
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
+C ++ + G ++ R++ + Q R E DTVL A GR + L L+ AGV
Sbjct: 229 DVRPQCHITGLKLTKKGNIRIRYEQ-QGQTR-ETKVDTVLCAVGRAPNLQGLGLDRAGVH 286
Query: 315 CVSNSGKIIA----ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
+N I+A E +TN +I+AVGD + LTPVAI GR A F + +
Sbjct: 287 LRTNRQGIVAIAVDEYYRTNQEHIFAVGDCTN-RVNLTPVAIAEGRAFADTQFGNLPRTL 345
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
Y+N+ + VF+ E VGLSE A A+ G + V++Y A ++P + R +K
Sbjct: 346 SYENIPSAVFSQPEAASVGLSEAQAKAKLGEENVKIYRAAFRPMYHSLTGRP-EQVIVKL 404
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
V + +R+LG H VG A EVIQG A A+K
Sbjct: 405 V-VENNTERVLGAHMVGDNAAEVIQGIAIALK 435
>UniRef50_A1AVW4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
sulfur-oxidizing symbionts|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Ruthia magnifica subsp. Calyptogena magnifica
Length = 443
Score = 248 bits (608), Expect = 2e-64
Identities = 163/447 (36%), Positives = 239/447 (53%), Gaps = 36/447 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
DYD+ IG GSGGL+ + A G K +++ +GGTCVNVGC+PKK+M
Sbjct: 4 DYDMIAIGAGSGGLSAVERAAEYGRKCLIIEVKI---------IGGTCVNVGCVPKKVMW 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSV-NWVTRVDLREKKIDYV 137
AA G I A +G+EV +W L N+IKS+ NW L++ IDY+
Sbjct: 55 FAANTGSIIKNAKGFGFEVEQKG---FSWKKLKVGRDNYIKSITNWYDSY-LQKLGIDYI 110
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
+G G+ D + + NG KE TA+ I+++ G P P I G+ EY I+SD+ F+L
Sbjct: 111 HGFGQLVDKNIVSV---NG--KEYTAEYIILSSGEEPAVPHIEGS-EYGITSDNFFALEA 164
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVF 256
P K V+G GYIG+E AG LN+LG T+ R+ LRGFD + + + G+
Sbjct: 165 LPKKVAVIGGGYIGVELAGVLNALGSEVTLFCRADKLLRGFDSMIQNTLDKDYSSHGITI 224
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
H+ V K +T T + FDT++ A GR +T+ L L+ AGV C
Sbjct: 225 HHNTQIDKVSKNKT---------LFTNQGAFTGFDTIIWAVGRNPMTQHLGLKVAGVKCD 275
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT-QPMDYDNV 375
+ + TNV NI+A+GDV G+ LTPVAI AGR L+ R++ T + +DY+N+
Sbjct: 276 QKGFIQTDKFQTTNVDNIFALGDV-TGRTSLTPVAIAAGRRLSDRLYNNMTDRHLDYNNI 334
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
AT VF+ G VGL+E A A DK+++Y + + P + + LK V +
Sbjct: 335 ATVVFSHPPIGMVGLTE--AQANEKFDKIKIYKSEFTPMADALLEHKTTTA-LKLVCAGD 391
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
++++G H +G A E++QGFA A+K
Sbjct: 392 -NEKVIGCHIMGHGADEILQGFAMAIK 417
>UniRef50_A1D1G1 Cluster: Glutathione reductase; n=7; cellular
organisms|Rep: Glutathione reductase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 554
Score = 246 bits (601), Expect = 1e-63
Identities = 156/452 (34%), Positives = 239/452 (52%), Gaps = 23/452 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVN-LGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
YD V+GGGSGG A+ A GAK +++ GGTCVNVGC+PKK+
Sbjct: 91 YDYIVLGGGSGGSGSARRAAGWYGAKTLIVE---------SGRAGGTCVNVGCVPKKMTW 141
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A + E++H YG+++P +KIN+ E +K +N + ++ ID V+
Sbjct: 142 NFASVNEALHVGEHYGYDIPK--DVKINYRQFKETRDAVVKRLNGAYERNWGKEGIDLVH 199
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
G F + + TL +G+K +A +I+IA GGRP P + GA E+ I+SD F +
Sbjct: 200 GRARFVEPKVIEVTLSDGAKARYSAPHILIATGGRPTIPPVKGA-EHGITSDGFFEIEEL 258
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P K VVGAGYI +E AG + ++G + +R LR FD + + +T E GV H
Sbjct: 259 PPKVAVVGAGYIAVELAGVMAAVGVETHMFIRGETMLRKFDPMIQKTMTERYEATGVRMH 318
Query: 258 NKCVPL-SVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
K V+ ++ G+ K + + E+ F+ +L A GR + L+LE GV +
Sbjct: 319 KKHGGFKEVQLVKDGKGKDKVLKLIGNDGSEEEFNELLWAIGRQPEVEDLHLEVPGVK-L 377
Query: 317 SNSGKIIAETEQ-TNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMF---AGATQPMDY 372
+ SG I+ + Q T+ +YA+GDV G ELTPVAI AGR L R+F A + + Y
Sbjct: 378 NESGHIVVDQYQNTSADGVYALGDV-TGVAELTPVAIAAGRQLGSRLFGPPALKSAKLSY 436
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFI--PQRNIRNCYLKA 430
+N+ T VF E G +GL+E A R+G DKV+VY+ + + + + +N
Sbjct: 437 ENIPTVVFAHPEVGTIGLTEPQARQRYGDDKVKVYYTKFTAMYYDVLPAEEKKKNPTEFK 496
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ++++GLH +G GE++QGF A+K
Sbjct: 497 IVCVGPEEKVVGLHILGLGVGEMLQGFGVAIK 528
>UniRef50_P41921 Cluster: Glutathione reductase; n=39; cellular
organisms|Rep: Glutathione reductase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 483
Score = 243 bits (594), Expect = 9e-63
Identities = 153/463 (33%), Positives = 252/463 (54%), Gaps = 27/463 (5%)
Query: 9 KFKNILAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVN 68
+ + + T YD VIGGGSGG+A A+ A + GAK +++ LGGTCVN
Sbjct: 13 QIRTMSTNTKHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKA---------LGGTCVN 63
Query: 69 VGCIPKKLMHQAALLGESIHEAVAYG-WEVPSLDA--IKINWPALTEAVQNHIKSVNWVT 125
VGC+PKK+M A+ L + A YG ++ LD + NWP + ++ +N +
Sbjct: 64 VGCVPKKVMWYASDLATRVSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIY 123
Query: 126 RVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPD-IPGAVE 184
+ +L ++K+D V G F + ++ + + +A +I++A GG+ +P+ IPG E
Sbjct: 124 QKNLEKEKVDVVFGWARFNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-FE 182
Query: 185 YCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQ 243
SD F L P K +VVGAGYIG+E AG + LG +++R LR FD+ +
Sbjct: 183 LGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQN 242
Query: 244 AVTSEMEQKGVVFHNKCVPLSVEK-LETGQLKARWQNTETQERGEDVFDTVLMATGRYAL 302
+T ++G+ H + VEK +ET +LK ++++ +DV D ++ GR +
Sbjct: 243 TITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSI---DDV-DELIWTIGRKS- 297
Query: 303 TKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRM 362
+ E G+ S+ I E + TNV NIY++GDV+ GK ELTPVAI AGR L+ R+
Sbjct: 298 HLGMGSENVGIKLNSHDQIIADEYQNTNVPNIYSLGDVV-GKVELTPVAIAAGRKLSNRL 356
Query: 363 FAG---ATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIP 419
F +DY+NV + +F+ E G +G+SE+ A+ ++G + ++VY++ K T +
Sbjct: 357 FGPEKFRNDKLDYENVPSVIFSHPEAGSIGISEKEAIEKYGKENIKVYNS--KFTAMYYA 414
Query: 420 QRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ++ + ++++GLH VG + E++QGF A+K
Sbjct: 415 MLSEKSPTRYKIVCAGPNEKVVGLHIVGDSSAEILQGFGVAIK 457
>UniRef50_Q5ZY02 Cluster: Glutathione reductase; n=4; Legionella
pneumophila|Rep: Glutathione reductase - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 454
Score = 241 bits (589), Expect = 4e-62
Identities = 154/449 (34%), Positives = 240/449 (53%), Gaps = 28/449 (6%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T +DL V+GGGSGG+A A A GAKV V++ + LGGTCVN+GC+PKK+
Sbjct: 5 TKHFDLIVLGGGSGGIASAVRAAQYGAKVAVIE---------QNHLGGTCVNLGCVPKKI 55
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
M+ A+ + E++H++ YG+ + + K++W L +I+ + + KI
Sbjct: 56 MYNASSIAETLHKSPDYGFFLEN--NAKLDWKRLVNKRNAYIERLRENYEKRFSQHKITL 113
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLG 196
+ G G F D ++ T+ + + A++I+IA G P P I G +++ I SD FSL
Sbjct: 114 IQGKGIFHDQSSI--TIDHTIYQ---AEHIIIATGSEPALPAING-IKHAIDSDGFFSLT 167
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVV 255
P K V+G+GYIG+E AG LNSLG +L+R PL FD + + M+++G+
Sbjct: 168 KLPAKVAVIGSGYIGVELAGILNSLGSETHLLMRGTRPLSRFDHMIGDTLMEIMQKQGIC 227
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
H ++ G+ Q+ E D ++ A GR T LNL+ V
Sbjct: 228 IHQNHKAQAIHLHSDGRKSILCQSGSIIEN----IDVIISAVGRKPRTGNLNLDKINVN- 282
Query: 316 VSNSGKIIAET-EQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP-MDYD 373
+ + G I+ + + T+V IYA+GDV P LTPVAI AGR LA R+F ++YD
Sbjct: 283 MDDKGLILVDAFQNTSVKGIYAIGDVTNA-PALTPVAIAAGRRLADRIFGNQPDACLNYD 341
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
N+ + VF+ G VGL+E A+ ++G +K+++Y + P + +K V L
Sbjct: 342 NICSVVFSHPPSGSVGLTEHEAIEKYGKNKIKIYQTRFIPMYDALSIDKTPTA-MKLVTL 400
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ++I+GLH VG A E++QGF A+K
Sbjct: 401 GK-KEKIIGLHVVGYSADEMLQGFGVAIK 428
>UniRef50_P42770 Cluster: Glutathione reductase, chloroplast
precursor; n=83; cellular organisms|Rep: Glutathione
reductase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 565
Score = 239 bits (584), Expect = 1e-61
Identities = 155/448 (34%), Positives = 228/448 (50%), Gaps = 22/448 (4%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTV--LDYVTPSPQGTKWGLGGTCVNVGCIPKK 75
YD+DL IG GSGG+ ++ A + GA V L + T S T G+GGTCV GC+PKK
Sbjct: 86 YDFDLFTIGAGSGGVRASRFATSFGASAAVCELPFSTISSD-TAGGVGGTCVLRGCVPKK 144
Query: 76 LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKID 135
L+ A+ ++ +GW+ + + +W L ++ + + + L + +
Sbjct: 145 LLVYASKYSHEFEDSHGFGWKYETEPSH--DWTTLIANKNAELQRLTGIYKNILSKANVK 202
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSL 195
+ G G+ D HT+ + K T +NI+IAVGGRP PDIPG E+ I SD L
Sbjct: 203 LIEGRGKVIDPHTV-----DVDGKIYTTRNILIAVGGRPFIPDIPGK-EFAIDSDAALDL 256
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGV 254
P K +VG GYI LE AG N L V +R LRGFD+ + V +M +G+
Sbjct: 257 PSKPKKIAIVGGGYIALEFAGIFNGLNCEVHVFIRQKKVLRGFDEDVRDFVGEQMSLRGI 316
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
FH + P ++ K G + T + + F V+ ATGR TK L LE GV
Sbjct: 317 EFHTEESPEAIIKAGDGSFSLK-----TSKGTVEGFSHVMFATGRKPNTKNLGLENVGVK 371
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
N + E QT+V +I+AVGDV + + LTPVA+ G LA+ +F DY
Sbjct: 372 MAKNGAIEVDEYSQTSVPSIWAVGDVTD-RINLTPVALMEGGALAKTLFQNEPTKPDYRA 430
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V VF+ G VGL+EE A+ ++G V+VY + ++P + + R ++K +
Sbjct: 431 VPCAVFSQPPIGTVGLTEEQAIEQYG--DVDVYTSNFRPLKATLSGLPDR-VFMKLIVCA 487
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
++LG+H G + E+IQGF AVK
Sbjct: 488 NT-NKVLGVHMCGEDSPEIIQGFGVAVK 514
>UniRef50_Q2IA26 Cluster: Chloroplast glutathione reductase; n=1;
Pavlova lutheri|Rep: Chloroplast glutathione reductase -
Pavlova lutherii (Monochrysis lutheri)
Length = 446
Score = 237 bits (581), Expect = 3e-61
Identities = 147/408 (36%), Positives = 220/408 (53%), Gaps = 23/408 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
Y+ VIG GSGG+A A+ A GAKV V++ LGGTCVNVGC+PKKL
Sbjct: 48 YEYLVIGAGSGGIASARRAAQYGAKVAVVERAR---------LGGTCVNVGCVPKKLFFT 98
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + E++H A YG +V + K +W +I ++N + +++ K+++V G
Sbjct: 99 AGVHMEAMHTAKGYGLDVGTPP--KFDWEGFKARRDAYIANLNGIYLRNMQNSKVEFVEG 156
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
F DA T+ T TA NI+IA GG+P +P +PG E +SDD F L H P
Sbjct: 157 YASFVDAKTVEVT----GHGRFTADNILIAAGGKPIHPPVPGG-ELAKTSDDFFDLEHQP 211
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRS--VPLRGFDQQMAQAVTSEMEQKGVVFH 257
+VVGAGY+ +E A ++ LG T++ R V GFD + + SEME++G+
Sbjct: 212 RTAVVVGAGYVAVELAFIMHELGTDTTLVCRGEKVLRHGFDPMVQDVLNSEMERQGISMR 271
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
K S++ E G + +++ + G DV VL A GR + + LE AGV
Sbjct: 272 RKTELGSIKLAEDGTYEVTFKDG-SMLTGIDV---VLYAAGRRPILTGMCLENAGVELSD 327
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP-MDYDNVA 376
+ E E+TNV I+A+GDV EL PVAI AGR L+ R++ G + ++YD +
Sbjct: 328 RGFITVDEYERTNVPGIHALGDVTTTGYELAPVAIAAGRRLSDRLYGGEPRARLEYDRIP 387
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIR 424
T VF+ G VGL+E AL ++G V+VY + +KP + + + +++
Sbjct: 388 TVVFSHPPIGTVGLTEPDALEQYGEASVKVYKSSFKPMHYAMCEPDLK 435
>UniRef50_P23189 Cluster: Glutathione reductase; n=42;
Proteobacteria|Rep: Glutathione reductase - Pseudomonas
aeruginosa
Length = 451
Score = 237 bits (579), Expect = 6e-61
Identities = 156/448 (34%), Positives = 235/448 (52%), Gaps = 30/448 (6%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
++D+DL VIG GSGG+ A+ A GA+V V + +++ LGGTCVNVGC+PKKL
Sbjct: 2 SFDFDLFVIGAGSGGVRAARFAAGFGARVAVAE--------SRY-LGGTCVNVGCVPKKL 52
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
+ A E +A AYGW S + +W L I+ +N + R L +
Sbjct: 53 LVYGAHFSEDFEQARAYGW---SAGEAQFDWATLIGNKNREIQRLNGIYRNLLVNSGVTL 109
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLG 196
+ G DAH++ +G + +AK+I++A GG P PDIPG E+ I+S++ F L
Sbjct: 110 LEGHARLLDAHSVEV---DGQR--FSAKHILVATGGWPQVPDIPGK-EHAITSNEAFFLE 163
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV-RSVPLRGFDQQMAQAVTSEMEQKGVV 255
P + LVVG GYI +E A N LG T+L R + LRGFD+ + + + E+ +KG+
Sbjct: 164 RLPRRVLVVGGGYIAVEFASIFNGLGAETTLLYRRDLFLRGFDRSVREHLRDELGKKGLD 223
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
++K G L A ++ E D V ATGR + L LE V
Sbjct: 224 LQFNSDIARIDKQADGSLAATLKDGRVLEA-----DCVFYATGRRPMLDDLGLENTAVKL 278
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT-QPMDYDN 374
+ E QT+ +I A+GDV+ G+ +LTPVA+ G +ARR+F +P+DY
Sbjct: 279 TDKGFIAVDEHYQTSEPSILALGDVI-GRVQLTPVALAEGMAVARRLFKPEEYRPVDYKL 337
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
+ T VF+ G VGL+EE AL+ KV+++ + ++P + + + L + +
Sbjct: 338 IPTAVFSLPNIGTVGLTEEEALS--AGHKVKIFESRFRPMKLTLTDDQEKT--LMKLVVD 393
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
R+LG H VG AGE++QG A A+K
Sbjct: 394 AHDDRVLGCHMVGAEAGEILQGIAVAMK 421
>UniRef50_A3TUM1 Cluster: Glutathione-disulfide reductase; n=2;
Alphaproteobacteria|Rep: Glutathione-disulfide reductase
- Oceanicola batsensis HTCC2597
Length = 453
Score = 234 bits (573), Expect = 3e-60
Identities = 165/447 (36%), Positives = 225/447 (50%), Gaps = 31/447 (6%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVN-LGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
+DYDL VIGGGSGG+ A+ A GA+V + + + GGTCV GC+PKKL
Sbjct: 4 FDYDLFVIGGGSGGVRAARVAAGETGARVALAE---------ESRYGGTCVIRGCVPKKL 54
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
M A+ E + +A AYGWE L +W + + + + + L ++
Sbjct: 55 MVFASGYAEMVEDARAYGWE---LGDGTFHWDTFRPKLDAELDRLEGIYKKLLDTPGVER 111
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLG 196
+ +DAHT+ L +G+ K TAK+I++A GGRP P++ A E I SDD+F L
Sbjct: 112 FDQRARIRDAHTV--ELADGTTK--TAKHILVATGGRPVRPEMENA-ELGIVSDDVFQLE 166
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVV 255
P LVVG GYI E A LN +G T R LRGFD + V EM KGV
Sbjct: 167 TLPKSVLVVGGGYIACEFACILNGMGVEVTQYYRGAQILRGFDDEARGLVAEEMNAKGVD 226
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
H C +E G W + E VFD V+ ATGR T L LE AGV
Sbjct: 227 IH--CGTNLLEMRREGD--GIW--VKATNGSERVFDKVIFATGRRPNTDDLGLEEAGVEL 280
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
++ + +T+V +IYA+GDV + + LTPVAI G +F G D++ +
Sbjct: 281 GRRGEVVVDDYSRTSVPSIYAIGDVTD-RANLTPVAIREGMAFVETVFRGNPTKPDHELI 339
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
T +FT E G VGLSEE A + + +EVY ++P + R R +K + RE
Sbjct: 340 PTAIFTQPEMGTVGLSEEAAREQ---EPIEVYATSFRPMQTVFAGRPDR-VMMKLIVSRE 395
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
+R+LG H V P AGE+IQ AVK
Sbjct: 396 T-RRVLGCHIVAPQAGEMIQLAGIAVK 421
>UniRef50_Q5FQ43 Cluster: Glutathione reductase; n=3;
Acetobacteraceae|Rep: Glutathione reductase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 483
Score = 233 bits (569), Expect = 1e-59
Identities = 162/452 (35%), Positives = 227/452 (50%), Gaps = 38/452 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
D+DL VIG GSGG+ CA+ A GA+V + + WG GTCVN+GC+PKKLM
Sbjct: 23 DFDLFVIGAGSGGVRCARIAAQNGARVAIAER-------RHWG--GTCVNLGCVPKKLMV 73
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
AA G I +A +YGW+V + +W L A I+ +N + L + +
Sbjct: 74 YAAEYGREIADAPSYGWDV---KPVAHDWSTLISAKDREIERLNRIYVSMLEKAGVTLFT 130
Query: 139 GLGEFKDAHTL----IATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFS 194
G F DAHT+ + S + + AKNIVIA G P +IPGA E+ I SDD F
Sbjct: 131 GDASFVDAHTVEIGPSELAPDASVQRVRAKNIVIATGSTPTRLNIPGA-EHAIVSDDAFH 189
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKG 253
L P + V+G+GYIG+E AG LG ++ R +PLRGFD +M ++ + G
Sbjct: 190 LADRPERVAVIGSGYIGIEFAGIFAGLGSKVDLVFRQQLPLRGFDHEMRAHLSELLPLNG 249
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDT--VLMATGRYALTKTLNLEAA 311
+ H P +EK+ G G DV +T V MATGR+ L L A
Sbjct: 250 IKAHPGRSPERIEKVADGY--------RLHLEGGDVIETDCVFMATGRHPNLAPLKLGNA 301
Query: 312 GVTCVSNSGKIIAETEQ--TNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
GV + G+I A+ + TNV+ IYA+GDV + LTP AI G +LA R+F +
Sbjct: 302 GV--ATWDGRIPAKPDDATTNVAGIYAIGDVTD-TYNLTPTAIAEGHILAERLFGEPGRE 358
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
+ VF VGLSEE A+ H V++Y + + P + R + L
Sbjct: 359 WSFATTPKAVFFSQPLATVGLSEEEAVQSH---DVDIYTSSFTPMRQTLSGRKGKT--LM 413
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ + + +LG H +GP A E+IQG A A+
Sbjct: 414 KLVVDAKSKIVLGAHMIGPDAPEIIQGLAIAI 445
>UniRef50_P48638 Cluster: Glutathione reductase; n=57; Bacteria|Rep:
Glutathione reductase - Anabaena sp. (strain PCC 7120)
Length = 459
Score = 233 bits (569), Expect = 1e-59
Identities = 158/457 (34%), Positives = 233/457 (50%), Gaps = 36/457 (7%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T+DYDL VIG GSGGLA +K A + GAKV + + +GGTCV GC+PKKL
Sbjct: 2 TFDYDLFVIGAGSGGLAASKRAASYGAKVAIAENDL---------VGGTCVIRGCVPKKL 52
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
M + +A YGW+V + +NW ++ ++ ++ + L + ++
Sbjct: 53 MVYGSHFPALFEDAAGYGWQVGKAE---LNWEHFITSIDKEVRRLSQLHISFLEKAGVEL 109
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLG 196
++G D HT+ + G +K TA I+IAVGGRP P++PG +EY I+S++IF L
Sbjct: 110 ISGRATLVDNHTV----EVGERK-FTADKILIAVGGRPIKPELPG-MEYGITSNEIFHLK 163
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVV 255
P ++G+GYIG E AG + LG T + R L+GFD+ + + M G+
Sbjct: 164 TQPKHIAIIGSGYIGTEFAGIMRGLGSQVTQITRGDKILKGFDEDIRTEIQEGMTNHGIR 223
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
K V ++E++ G LK + + DVF L+ATGR L LE AGV
Sbjct: 224 IIPKNVVTAIEQVPEG-LKISLSGEDQEPIIADVF---LVATGRVPNVDGLGLENAGVDV 279
Query: 316 VSNSGK----------IIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG 365
V +S + + E QT+ NIYAVGDV + + LTPVAI GR A F
Sbjct: 280 VDSSIEGPGYSTMNAIAVNEYSQTSQPNIYAVGDVTD-RLNLTPVAIGEGRAFADSEFGN 338
Query: 366 ATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRN 425
+ ++ +AT VF+ + VGL+E A A+ G D V +Y ++P + R
Sbjct: 339 NRREFSHETIATAVFSNPQASTVGLTEAEARAKLGDDAVTIYRTRFRPMYHSFTGKQER- 397
Query: 426 CYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + + ++LG H VG A E+IQG A AVK
Sbjct: 398 -IMMKLVVDTKTDKVLGAHMVGENAAEIIQGVAIAVK 433
>UniRef50_A0ZGC8 Cluster: Glutathione reductase; n=2;
Nostocaceae|Rep: Glutathione reductase - Nodularia
spumigena CCY 9414
Length = 447
Score = 231 bits (566), Expect = 2e-59
Identities = 156/449 (34%), Positives = 236/449 (52%), Gaps = 31/449 (6%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T+DYDL VIG G+GGLA AK+A + G +V + + T +GGTCVN GC+PKKL
Sbjct: 2 TFDYDLFVIGTGTGGLAAAKQAASYGVRVAMAEQET---------IGGTCVNRGCVPKKL 52
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
+ AA + A +YGW S +W ++V HI+ +N+ LR I+
Sbjct: 53 IVYAADFAQDNQMANSYGW---SKCKRYFDWTLFMKSVHRHIEHINYSYCQQLRNAGIEI 109
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLG 196
+ F DAHTL NG ++TA I+IAVGG+P+ P IPG +EY I+S +F L
Sbjct: 110 IKERAVFVDAHTLDL---NG--HQVTADKILIAVGGKPNKPQIPG-IEYAITSRQMFHLP 163
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGVV 255
+ P + ++G GYIG E + +++LG T+L R + L GFD + V + ++G+
Sbjct: 164 YLPKRLAIIGGGYIGAEFSSMMHALGCKVTLLERDEMMLSGFDDDIRSGVQQGLSKRGIR 223
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVT 314
C + L+ G W T + E + DT+L+ATG A T+ L LE A V
Sbjct: 224 IFTNCTAEEITHLDEG-----WLLKTTGDCAETIAADTILVATGFSANTQNLGLEKAKVE 278
Query: 315 CVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
V G+I + E T NI+AVGD + + +LTPVA G A +F Q ++YD
Sbjct: 279 -VGKQGEIQVNEYFCTTQENIFAVGDCI-NRMQLTPVAKAEGMAFANTVFGNNPQTVNYD 336
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
V + VF+ E VG++E A + G + V+ Y ++P + + + +K V +
Sbjct: 337 YVPSAVFSRPEGSGVGMTEAQAREKFG-ESVKCYCKRFQPLLYQLVEAE-EPAMMKLV-V 393
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ Q++LG H +G A E+IQ A++
Sbjct: 394 DDNSQQVLGAHMLGENAAEIIQTLGVAIR 422
>UniRef50_A2C124 Cluster: Probable glutathione reductase; n=2;
Prochlorococcus marinus|Rep: Probable glutathione
reductase - Prochlorococcus marinus (strain NATL1A)
Length = 453
Score = 229 bits (561), Expect = 9e-59
Identities = 161/441 (36%), Positives = 239/441 (54%), Gaps = 30/441 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL VIG GSGGLA AK+A + GA V +++ G +GGTCV GC+PKKL+
Sbjct: 5 FDLIVIGAGSGGLAAAKKAASYGASVAIVE-------GDL--VGGTCVIRGCVPKKLLVC 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+ L ES A +YG++ D +KI L V+ + +N + L + ++ G
Sbjct: 56 GSSLLESFLSATSYGFD---FDNLKIKSEVLLANVRKEVHRLNELHENFLNKANVELFKG 112
Query: 140 LGEFKDAHTL-IATLKNGSK-KEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
GEF++++ + + KNG E+ + I+IAVGGRP P I GA +SDD+F L
Sbjct: 113 WGEFRNSNCVEVKDRKNGETLNELYGERILIAVGGRPKRPSIEGA-SLGWTSDDMFLLKS 171
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGV-- 254
P K +VGAGYI E A L+ LG T LVR LRGFD +++ ++T M+ KGV
Sbjct: 172 FPKKITIVGAGYIACEFACILHGLGVEVTQLVRGDRILRGFDFELSSSLTEAMKNKGVNI 231
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
F K +S K G L + T E + +L ATGR L LE AG+
Sbjct: 232 SFGEK---ISSLKGTPGSLIIK-----TNAGKEFDSNGLLFATGREPFLDGLKLEQAGIE 283
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ N K+ +E + TN+SNI+A+GDV + + LTPVAI GR A R + + ++Y+
Sbjct: 284 ILENKIKVDSEGK-TNISNIFAIGDVTD-RINLTPVAIDEGRKFADRNYGESDHKVNYNF 341
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V VF+ E VG++EE A+ G D ++VY + ++P +P+ + C LK + +
Sbjct: 342 VPYAVFSQPEIASVGMTEEKAIQSIGKDNIKVYRSIFRPLSKSLPKTGSK-CILKLI-VD 399
Query: 435 EAPQRILGLHFVGPVAGEVIQ 455
+ ++LG H +G A E+IQ
Sbjct: 400 KNNNKVLGCHMIGDNASEIIQ 420
>UniRef50_A4IXR1 Cluster: Glutathione-disulfide reductase; n=11;
Francisella tularensis|Rep: Glutathione-disulfide
reductase - Francisella tularensis subsp. tularensis
(strain WY96-3418)
Length = 453
Score = 229 bits (560), Expect = 1e-58
Identities = 162/448 (36%), Positives = 244/448 (54%), Gaps = 33/448 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+ +GGGSGG+A A +A G KV +++ K LGGTCVN GC+PKK M
Sbjct: 6 FDVISLGGGSGGIASAVQAAKFGKKVAIIE---------KRELGGTCVNRGCVPKKAMWY 56
Query: 80 AALLGESI-HEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A L E + H+ YG++V + NW L E +I +++ L + I + N
Sbjct: 57 GANLAEILKHDVAGYGFDV---EVKGFNWAKLKEKRATYIGNIHGFYDRLLDKWNITHFN 113
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFSLGH 197
G+FKD T++ L +G+ E+TA +I I+ G P P +I GA E I+SD+ F L
Sbjct: 114 NWGKFKDNKTIV--LDDGT--ELTADHIFISPGAYPIVPKNIEGA-ELGITSDEFFELEE 168
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLV-RSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P K ++VG GYIG+E AG LN+ G T++V R PL FD ++ A+ M+ +
Sbjct: 169 TPKKAVIVGGGYIGVEIAGVLNAHGTDTTIMVRRDKPLMEFDNCISDALVECMQMTDLNI 228
Query: 257 HNKCVPLSVEKLETGQ-LKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
N VEK TG LK T+T + EDV DT++ ATGR T L +E +
Sbjct: 229 MNHTNITKVEK--TGSTLKI---TTDTDKVLEDV-DTLIWATGRAPNTHNLGIENTDIR- 281
Query: 316 VSNSGKIIA-ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQ-PMDYD 373
+++ G I A E +TNV+ +Y++GD G P+LTPVAI GR LARR+F G T + +
Sbjct: 282 ITDKGVIPANEWSETNVAGVYSLGDA-SGVPQLTPVAIKTGRYLARRLFNGETNLKANLE 340
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ T +F+ G VGL+E+ A ++G + V+VY + + T + R + + +
Sbjct: 341 YIPTVIFSHPAIGTVGLTEKEARDKYGDENVKVYKSRF--TALYCAISGHRMPTVMKLVV 398
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAV 461
++I+G H +G E++QGFA A+
Sbjct: 399 TGDNEKIVGCHMIGLNVDEMLQGFAVAI 426
>UniRef50_Q1GTU0 Cluster: Glutathione reductase; n=12; Bacteria|Rep:
Glutathione reductase - Sphingopyxis alaskensis
(Sphingomonas alaskensis)
Length = 448
Score = 229 bits (559), Expect = 2e-58
Identities = 154/448 (34%), Positives = 231/448 (51%), Gaps = 32/448 (7%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+D+DL VIG GSGG+ ++ A + GA+V V + + +GGTCV GC+PKKL+
Sbjct: 4 FDFDLFVIGAGSGGVRASRIAASHGARVAVAE---------EHRVGGTCVIRGCVPKKLL 54
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
A E + +A +GWEVP + +W L + V + + + L K+
Sbjct: 55 VYGAHFAEDLKDARKFGWEVPD---CRFDWDVLRDNVLAEVDRLEGLYGQTLDNHKVRV- 110
Query: 138 NGLGEFKDAHTLIA--TLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSL 195
FK T++A T++ +E+TA+ I+IA GG PH PD PG+ E+ I+S+++F L
Sbjct: 111 -----FKTRATVVAPQTVRLADGQELTAERILIATGGWPHVPDFPGS-EHAITSNEVFHL 164
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGV 254
P + ++ G GYI E AG N G T++ R LRG+D+Q+ + KG+
Sbjct: 165 ETLPRRVVIAGGGYIANEFAGIFNEFGSKVTIVNRGDTILRGYDEQIRDRLLQISMTKGI 224
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
F +EK + G L E V D VL+ATGR TK L L+ GV
Sbjct: 225 DFKFNAPFEKIEKNDDGTLTIYLGGCE-----PIVADAVLVATGRVPNTKGLGLDEVGVD 279
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ E Q++V +IY VGDV + +LTPVAI G+ A +F G +DY N
Sbjct: 280 LDPTGAIRVDEHNQSSVPSIYGVGDV-TNRIQLTPVAIREGQAFADSVFGGHPTVVDYAN 338
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V + VF+ G VG++E A AR+ V VY + ++ + + RN R Y + +
Sbjct: 339 VPSAVFSHPPIGAVGMTE--AEARNKLGSVRVYTSDFRAMKNVLAGRNERALY--KMIVN 394
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
A +++GLH +GP A E++Q A AVK
Sbjct: 395 AATDQVVGLHMIGPDAPEILQAAAIAVK 422
>UniRef50_P39051 Cluster: Trypanothione reductase (EC 1.8.1.12) (TR)
(N(1),N(8)- bis(glutathionyl)spermidine reductase);
n=26; Eukaryota|Rep: Trypanothione reductase (EC
1.8.1.12) (TR) (N(1),N(8)- bis(glutathionyl)spermidine
reductase) - Trypanosoma brucei brucei
Length = 492
Score = 223 bits (544), Expect = 1e-56
Identities = 148/453 (32%), Positives = 221/453 (48%), Gaps = 21/453 (4%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAK-VTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+DL VIG GSGGL A L K V V+D T LGGTCVNVGC+PKKLM
Sbjct: 5 FDLVVIGAGSGGLEAGWNAATLYKKRVAVIDVQTHHGPPHYAALGGTCVNVGCVPKKLMV 64
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK-IDYV 137
A + + E+ +GWE ++K NW L A + +N + + +D+
Sbjct: 65 TGAQYMDHLRESAGFGWEFDG-SSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDFF 123
Query: 138 NGLGEFKDAHTLI----ATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIF 193
G G + + ++ A K+ K+ + A +I++A G P P IPG VE+CISS++ F
Sbjct: 124 LGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPG-VEHCISSNEAF 182
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSL---GYPATVLVR-SVPLRGFDQQMAQAVTSEM 249
L PP + L VG G+I +E AG N+ G T+ R ++ LRGFD+ + + VT ++
Sbjct: 183 YLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQL 242
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
G+ P V G +++ +T + D V+MA GR T L L
Sbjct: 243 TANGIEIMTNENPAKVSLNTDGSKHVTFESGKTLD-----VDVVMMAIGRIPRTNDLQLG 297
Query: 310 AAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
GV G + E +TNV NIYA+GD+ + + LTPVAI+ G L +F +
Sbjct: 298 NVGVKLTPKGGVQVDEFSRTNVPNIYAIGDITD-RLMLTPVAINEGAALVDTVFGNKPRK 356
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
D+ VA+ VF+ G GL EE A +KV VY + + P I + ++
Sbjct: 357 TDHTRVASAVFSIPPIGTCGLIEEVAAKEF--EKVAVYMSSFTPLMHNISGSKYKK-FVA 413
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + +LG+H +G A E+IQ ++
Sbjct: 414 KIVTNHSDGTVLGVHLLGDGAPEIIQAVGVCLR 446
>UniRef50_Q7V2B4 Cluster: Probable glutathione reductase; n=5;
Prochlorococcus marinus|Rep: Probable glutathione
reductase - Prochlorococcus marinus subsp. pastoris
(strain CCMP 1378 / MED4)
Length = 459
Score = 220 bits (538), Expect = 5e-56
Identities = 148/448 (33%), Positives = 235/448 (52%), Gaps = 28/448 (6%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+++DL V+G GSGGLA AK A + GAKV +++ +GGTCV GC+PKKLM
Sbjct: 8 FEFDLIVLGAGSGGLAAAKRAASYGAKVAIIEVNK---------IGGTCVIRGCVPKKLM 58
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
AA ++ + YG + S + I L + V+ + ++ + L++ +
Sbjct: 59 VYAANNRRNMLSSEGYG--LISKE-ITFESNILLKNVREEVSRLSVLHSNSLKKLNVKVF 115
Query: 138 NGLGEFKDAHTL--IATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSL 195
GLG F + +T+ + ++++AK+I+I+VGG+P +IPG ++ +SDDIF L
Sbjct: 116 EGLGRFLNQNTVEVVCPKTKNILRKVSAKSILISVGGKPKKLNIPGT-DFAWTSDDIFEL 174
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPL-RGFDQQMAQAVTSEMEQKGV 254
P K L+VG GYI E A +LG T L+R L GFD+ +++ + M G+
Sbjct: 175 KDFPKKLLIVGGGYIACEFASIFKNLGTEVTQLIRGENLLNGFDKDLSECLEKSMTSLGI 234
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVF-DTVLMATGRYALTKTLNLEAAGV 313
K S++K+ G T E G + D +L+ATGR K LNL+ +
Sbjct: 235 NLKFKNQLKSIKKINDGL-------ESTLESGSKLLTDNILVATGREPSLKRLNLDTLNL 287
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ + E +T++SNI+A+GD+++ +P LTPVAI GR+ A FA + ++Y+
Sbjct: 288 K-MDGIYLEVNELNKTSISNIFAIGDIVK-RPNLTPVAIEQGRVFADNYFAALKRKVNYE 345
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
N+ VFT E VGLSEE A + V+V+ + P ++N C LK V +
Sbjct: 346 NIPKAVFTIPEISTVGLSEEKANEIYSEVNVQVFKCNFTPMSNTF-KKNKSKCMLKLV-V 403
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ ++LG H G A E+IQ A ++
Sbjct: 404 NKKNDKVLGCHMFGEAASEIIQMVAVSL 431
>UniRef50_A1B892 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=3;
Alphaproteobacteria|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Paracoccus
denitrificans (strain Pd 1222)
Length = 466
Score = 218 bits (532), Expect = 3e-55
Identities = 155/444 (34%), Positives = 226/444 (50%), Gaps = 31/444 (6%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVN-LGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
+DYDL VIGGGSGG+ A+ A + GA+V + + + +GGTCV GC+PKKL
Sbjct: 3 FDYDLFVIGGGSGGVRAARIAASEYGARVGLAE---------ESRMGGTCVIRGCVPKKL 53
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
M A+ G + E+ YGW+ + +W + + + L ++
Sbjct: 54 MIFASQAGAAAAESRGYGWQ--GAGEGRFDWAEFHGKLGRELDRLEGAYTSGLVNAGVEV 111
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLG 196
DAHT+ L +G + +TAK+I+IA+GGRP PDIPG E + SDD+F+L
Sbjct: 112 HMQRARLHDAHTV--ELADGQR--LTAKHILIAIGGRPQRPDIPGK-ELGLISDDLFTLE 166
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRS-VPLRGFDQQMAQAVTSEMEQKGVV 255
PG+ LVVG G+I E A L LG + R LRGFD +M + VT ++ GV
Sbjct: 167 KLPGRVLVVGGGFIACEFATILQGLGSATVLAYRGDAVLRGFDGEMRRHVTEQLRAIGVD 226
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
P +++ G ++ ++FD V+ ATGR TK L LE AGV
Sbjct: 227 VRLGTNPARLDREGAGV------RVTFEDDSSEIFDAVMFATGRVPYTKGLGLEDAGVKL 280
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
++ E Q++V +I+AVGDV + + LTPVAI G A +F + +D+ V
Sbjct: 281 GRKGEIVVDEWSQSSVPSIFAVGDVTD-RVNLTPVAIREGHSFADTVFGARPRKVDHRLV 339
Query: 376 ATTVFT-PLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
A+ V+T P E +GL+EE A A AD VY A ++P + R +K +
Sbjct: 340 ASAVYTRPHELATIGLTEEEADACGPAD---VYVASFRPMRSLFAGSDAR-AVMKLIVDA 395
Query: 435 EAPQRILGLHFVGPVAGEVIQGFA 458
+ ++LG H GP AGE+IQ A
Sbjct: 396 QT-DKVLGCHIFGPEAGEMIQMIA 418
>UniRef50_P48639 Cluster: Glutathione reductase; n=5; cellular
organisms|Rep: Glutathione reductase - Burkholderia
cepacia (Pseudomonas cepacia)
Length = 449
Score = 218 bits (532), Expect = 3e-55
Identities = 148/446 (33%), Positives = 221/446 (49%), Gaps = 30/446 (6%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
YD+DL VIG GSGG+ A+ A GAKV + + ++ GGTCV GC+PKKL+
Sbjct: 4 YDFDLFVIGAGSGGVRAARIAAGHGAKVAIAE---------EYRFGGTCVIRGCVPKKLL 54
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
A+ G+ +A +GW A +W +L A I + V + + ++
Sbjct: 55 MYASQYGQGFEDAAGFGWHSA---ATSHSWTSLIAAKDAEIARLEGVYQRLIENANVEIF 111
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
G + + + T G+ ++A+ I+IA G RP P + GA I+SDD+F L
Sbjct: 112 KGRAQIAGPNRVTVT---GAS--VSARTILIATGARPVMPPVAGA-NLMITSDDVFDLPV 165
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGVVF 256
P + ++G GYI E AG N LG L R S LRGFD ++ + + E+++ G+
Sbjct: 166 GPPRIAIIGGGYIACEFAGIFNGLGRHVVQLHRGSQVLRGFDDELREHLGDELKKSGIDL 225
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
++VE+ + G L + + E D V+ ATGR T L LE V
Sbjct: 226 RLGVDVVAVER-QRGALSVQLTTGDAME-----VDAVMAATGRLPNTWGLGLETVDVGLD 279
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
N + E +T+ IYAVGDV + LTPVAIH G A +F G P +++NV
Sbjct: 280 QNGAIKVDEYSRTSSPGIYAVGDVTN-RLNLTPVAIHEGHAFADTVFGGKALPTEHENVP 338
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
VF+ + VGLSE A AR VE+Y + ++P + R+ + L + + +
Sbjct: 339 FAVFSQPQAASVGLSE--AQARDRYSNVEIYGSAFRPMRAALSGRDEK--ALVKLVVNGS 394
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
R++G H VG A E+IQG A A+K
Sbjct: 395 NDRVVGAHIVGADAAEIIQGIAVAIK 420
>UniRef50_Q5NN75 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=8; Sphingomonadales|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Zymomonas mobilis
Length = 448
Score = 214 bits (523), Expect = 4e-54
Identities = 148/450 (32%), Positives = 239/450 (53%), Gaps = 36/450 (8%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
YD+DL VIG GSGG+ ++ A + GA V + + ++ +GGTCV GC+PKK++
Sbjct: 4 YDFDLFVIGAGSGGVRASRIAASHGASVAIAE---------EYRIGGTCVIRGCVPKKML 54
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD-LREKKIDY 136
+ AA + +A +GW +P K +W L + V + VTR++ L + +D
Sbjct: 55 YYAADFAADLKKAQRFGWTLPEK---KFDWATLRDVVLSD------VTRLEGLYTQTLDN 105
Query: 137 VNGLGEFKDAHTLIAT---LKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIF 193
N + +K+ H +I + ++ S K+ITA+ I++AVG P DI GA EY ++S+++F
Sbjct: 106 -NHITHYKE-HAVIDSANQIRLASGKKITARYILVAVGAEPAKLDILGA-EYAVTSNEMF 162
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQK 252
L P + LVVG GYI E AG LNS G T+ LRG+D+++A + +
Sbjct: 163 LLPSLPKRALVVGGGYIANEFAGILNSFGVETTIATHGDRILRGYDEEIAARLVEIGQGH 222
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
G+ + ++K +G+L +++ E D VL A GR A ++ L L+ A
Sbjct: 223 GIDYRFNADIARIDKDSSGRLTTHFKDGSQIES-----DLVLFAIGRVAKSRDLGLDKAD 277
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
V ++ E +T+ +IYAVGDV + + +LTPVAI G+ A R+F +DY
Sbjct: 278 VKTNDRGAILVDEENRTSCPSIYAVGDVTD-RVQLTPVAIREGQAFADRVFGHKAASVDY 336
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
D + T VF+ GL+EE A R+ +++Y + ++P + R Y K V
Sbjct: 337 DTIPTAVFSHPPLASAGLTEEEAKKRY--KNIKIYKSNFRPMRNALIDSPDRALY-KMVV 393
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
++ ++LGLH +G + E+IQ A A+K
Sbjct: 394 DGDS-DKVLGLHLIGQDSPEIIQLAAVAIK 422
>UniRef50_Q6BPI1 Cluster: Glutathione reductase; n=6;
Saccharomycetales|Rep: Glutathione reductase -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 490
Score = 210 bits (512), Expect = 8e-53
Identities = 148/470 (31%), Positives = 238/470 (50%), Gaps = 42/470 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD VIGGGSGG+A A+ A + GAKV +++ +GGTCVNVGC+PKK+M
Sbjct: 10 YDYLVIGGGSGGVASARRAASYGAKVLLIELKFNK-------MGGTCVNVGCVPKKVMWY 62
Query: 80 AALLGESIHEAVAYGWEVPSLDAIK---INWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
A L E H +YG D +K +W + ++K +N + +L+ + +DY
Sbjct: 63 AGDLAEKRHHLKSYGLSTTD-DKVKYGDFDWSTFKDKRDAYVKRLNGIYERNLKNEGVDY 121
Query: 137 VNGLGEFKDAH-----TL-----IATLKNGS--KKE----ITAKNIVIAVGGRPHYPDIP 180
+ G F +++ TL ++ L+ G KK+ +IA GG P
Sbjct: 122 IYGFAHFANSNGDVEVTLTGDQELSFLEEGKEFKKDEKLVFAGSKTLIATGGYAINPPNV 181
Query: 181 GAVEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQ 239
E +SD F L P VVGAGYIG+E +G +LG +++R LR FD+
Sbjct: 182 EGHELGTTSDGFFELQKQPKSVAVVGAGYIGVELSGIFKALGSETHLVIRGDTVLRSFDE 241
Query: 240 QMAQAVTSEMEQK-GVVFHNKCVPLS-VEKLETGQLKARWQNTETQERGEDVFDTVLMAT 297
+ ++T K GV + +S VEK++ + K N + E D ++
Sbjct: 242 SIQNSITDYYTDKLGVNIIKQSGSVSKVEKIDGDRKKITLGNGQVLE-----VDELIWTM 296
Query: 298 GRYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRL 357
GR +L + L+ GVT + + +QT NI+++GDV+ GK ELTPVAI AGR
Sbjct: 297 GRKSLI-NIGLDKVGVTLNDKQQVDVDQFQQTANPNIFSLGDVI-GKVELTPVAIAAGRR 354
Query: 358 LARRMFAG----ATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKP 413
L+ R+F+G +DY NV + +F+ E G +GLS + A ++G D++++Y + +
Sbjct: 355 LSNRLFSGDKAFENDHLDYSNVPSVIFSHPEAGSIGLSCKEAKEKYGEDQIKIYKSKFNA 414
Query: 414 TEF-FIPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + ++++ V ++++GLH VG + E++QGF A+K
Sbjct: 415 MYYAMMEDDSLKSPTSYKVVCAGEDEKVVGLHIVGDSSAEILQGFGVAIK 464
>UniRef50_O43998 Cluster: Glutathione reductase homolog; n=1;
Toxoplasma gondii|Rep: Glutathione reductase homolog -
Toxoplasma gondii
Length = 484
Score = 204 bits (499), Expect = 3e-51
Identities = 154/459 (33%), Positives = 226/459 (49%), Gaps = 35/459 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL VIGGGSGGLACA+ A +V + D G + LGGTCVNVGC+PKK+M
Sbjct: 9 FDLFVIGGGSGGLACARRAATYNVRVGLAD-------GNR--LGGTCVNVGCVPKKVMWC 59
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + E++HE + + V + W L N+IK +N + +L+ + +
Sbjct: 60 VASVHETLHELKNFAFTVK--EQPTFCWRTLKTNRDNYIKRLNNIYLNNLKNSGVTFFPA 117
Query: 140 LGEFKD---------AHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSD 190
F AH ++ +G+++ +TA +++IA GGRP I G E+ I+SD
Sbjct: 118 YARFAKPEAKTDGGLAHAIVLKSADGNEETVTADHVLIASGGRPAKAGIEGE-EHTINSD 176
Query: 191 DIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEM 249
F L P K ++GAGYI +E AG ++ + VR+ LR FD ++ V M
Sbjct: 177 GFFELEEMPQKVALLGAGYIAVEFAGVFAAMKCETHLFVRNERALRKFDDMISMRVDEFM 236
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
+ GV H V +V + L N G + R ++ L+
Sbjct: 237 RKAGVQIHPHSVAKAVRQEADKSLTLELTNGRIFS-GLRFRYCICWPRPR---SRESGLD 292
Query: 310 AAGVTCVSNSGKIIA-ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG-AT 367
GV + G I+A E + T+V IYAVGDV GK ELTPVAI AGR LA R+F G
Sbjct: 293 VVGVK-QRHGGYIVADEFQNTSVEQIYAVGDV-SGKIELTPVAIAAGRRLADRLFGGLCN 350
Query: 368 QPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHA----FYKPTEFFIPQRNI 423
+D V T VF+ CVGL+E A A +G ++VY Y P+
Sbjct: 351 AKLDSACVPTVVFSHPPAACVGLTEAEAKATYGEKDIKVYTGTSVNLYYGAWPVAPEEKP 410
Query: 424 RNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ++K + ++ +++GLH VG A E+IQGF A++
Sbjct: 411 KT-FIKMICVKSQMLKVVGLHVVGMGADEMIQGFGVAME 448
>UniRef50_Q3UY43 Cluster: Adult male olfactory brain cDNA, RIKEN
full-length enriched library, clone:6430537F14
product:thioredoxin reductase 3, full insert sequence;
n=3; Eutheria|Rep: Adult male olfactory brain cDNA,
RIKEN full-length enriched library, clone:6430537F14
product:thioredoxin reductase 3, full insert sequence -
Mus musculus (Mouse)
Length = 581
Score = 200 bits (489), Expect = 5e-50
Identities = 96/199 (48%), Positives = 136/199 (68%), Gaps = 1/199 (0%)
Query: 265 VEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSNSGKI-I 323
+EK G+LK ++TE E E +++TVL+A GR + T+ + LE GV +GKI +
Sbjct: 343 LEKGLPGKLKVVAKSTEGPETVEGIYNTVLLAIGRDSCTRKIGLEKIGVKINEKNGKIPV 402
Query: 324 AETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVATTVFTPL 383
+ EQTNV ++YA+GD+L+GKPELTPVAI AG+LLARR+F + + DY N+ TTVFTPL
Sbjct: 403 NDVEQTNVPHVYAIGDILDGKPELTPVAIQAGKLLARRLFGVSLEKCDYINIPTTVFTPL 462
Query: 384 EYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAPQRILGL 443
EYGC GLSEE A+ + + +EVYH + P E+ + R+ CY K + + +R++G
Sbjct: 463 EYGCCGLSEEKAIEMYKKENLEVYHTLFWPLEWTVAGRDNNTCYAKIICNKFDNERVVGF 522
Query: 444 HFVGPVAGEVIQGFAAAVK 462
H +GP AGE+ QGFAAA+K
Sbjct: 523 HLLGPNAGEITQGFAAAMK 541
Score = 200 bits (488), Expect = 6e-50
Identities = 94/151 (62%), Positives = 113/151 (74%), Gaps = 5/151 (3%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+DYDL +IGGGSGGL+CAKEA NLG KV VLD+V PSPQGT WGLGGTCVNVGCIPKKLM
Sbjct: 209 HDYDLIIIGGGSGGLSCAKEAANLGKKVMVLDFVVPSPQGTTWGLGGTCVNVGCIPKKLM 268
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
HQAALLG ++ +A YGWE +K NW A+TEA+Q+HI S+NW RV LREK + YV
Sbjct: 269 HQAALLGHALQDAKKYGWEYN--QQVKHNWEAMTEAIQSHIGSLNWGYRVTLREKGVTYV 326
Query: 138 NGLGEFKDAHTL-IATLKNG--SKKEITAKN 165
N GEF D H + + L+ G K ++ AK+
Sbjct: 327 NSFGEFVDLHKIKVQQLEKGLPGKLKVVAKS 357
>UniRef50_UPI0000E4A80A Cluster: PREDICTED: similar to thioredoxin
reductase TrxR1; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to thioredoxin reductase TrxR1 -
Strongylocentrotus purpuratus
Length = 397
Score = 199 bits (486), Expect = 1e-49
Identities = 95/190 (50%), Positives = 128/190 (67%)
Query: 273 LKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVS 332
LK ++ TE E +TVLMA GR A T L LE GV +GKI EQTNV
Sbjct: 168 LKVHFKRTEGGEESSIECNTVLMAVGRDACTTELGLEKVGVITSPKNGKIPCTNEQTNVP 227
Query: 333 NIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVATTVFTPLEYGCVGLSE 392
++YAVGD+LEG ELTPVAI AG+LLA+R+++ +T+ DY NV TTVFTPLEYG GL E
Sbjct: 228 HVYAVGDILEGGHELTPVAIEAGKLLAKRLYSTSTRQCDYVNVPTTVFTPLEYGSCGLPE 287
Query: 393 ETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGE 452
E A+A++G + +EVYH +++P EF + R + CY K + + A ++++G H +GP AGE
Sbjct: 288 EDAVAKYGEENLEVYHTYFQPLEFTVSHREVNACYAKIICDKTANEKVVGFHVLGPNAGE 347
Query: 453 VIQGFAAAVK 462
+ QGFA A+K
Sbjct: 348 MTQGFAVAMK 357
>UniRef50_A3VZL9 Cluster: Glutathione-disulfide reductase; n=1;
Roseovarius sp. 217|Rep: Glutathione-disulfide reductase
- Roseovarius sp. 217
Length = 427
Score = 196 bits (479), Expect = 8e-49
Identities = 131/357 (36%), Positives = 194/357 (54%), Gaps = 27/357 (7%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+DYDL VIGGGSGG+ A+ A GA+V + + + GGTCV GC+PKKLM
Sbjct: 3 FDYDLFVIGGGSGGVRAARVAAQSGARVALAE---------EDRYGGTCVIRGCVPKKLM 53
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
A+ ++ +A AYGW V A +WP + + + + V R L+ ++
Sbjct: 54 VFASEYRGAMADAQAYGWTV---HAGGFDWPTFRDKLHAELDRLEGVYRGVLKTNGVETY 110
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
+ D HT+ L +G++ ++AK+I+IA GGRP PD+PGA E+ I+S++IF L
Sbjct: 111 DCRAALVDPHTV--ELADGTR--LSAKHILIATGGRPVKPDLPGA-EHAITSNEIFHLEK 165
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVF 256
P L++G GYI E A LN LG T R LRGFD + V+ EM G+
Sbjct: 166 LPRSILIIGGGYIACEFACVLNGLGVQVTQFYRGAQVLRGFDDEARGLVSEEMIASGIKL 225
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
H + ++E ++ ++ ++ T T E VF+ V+ ATGR T+ L LEA GV V
Sbjct: 226 H---LGTNIEAMDV--VEGGYRVTGTNG-SEAVFEQVMFATGRTPNTENLGLEATGVA-V 278
Query: 317 SNSGKIIAET-EQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
G+I+ ++ QT V ++YA+GDV + + LTPVAI G +F G P+D+
Sbjct: 279 GRKGEILVDSYSQTGVPSVYAIGDVTD-RVNLTPVAIREGIAFVETVFKGNPTPVDH 334
>UniRef50_Q94655 Cluster: Glutathione reductase; n=11;
Plasmodium|Rep: Glutathione reductase - Plasmodium
falciparum (isolate K1 / Thailand)
Length = 500
Score = 192 bits (468), Expect = 2e-47
Identities = 154/490 (31%), Positives = 235/490 (47%), Gaps = 69/490 (14%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIGGGSGG+A A+ A AKV +++ K LGGTCVNVGC+PKK+M
Sbjct: 3 YDLIVIGGGSGGMAAARRAARHNAKVALVE---------KSRLGGTCVNVGCVPKKIMFN 53
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA + + + + YG++ N P L E +I+ +N + R +L + K+D G
Sbjct: 54 AASVHDILENSRHYGFDTK----FSFNLPLLVERRDKYIQRLNNIYRQNLSKDKVDLYEG 109
Query: 140 LGEF-KDAHTLIATLKNGSKKE--------ITAKNIVIAVGGRPHYPDIPGAVEYCISSD 190
F + LI K+ + K+ + +NI+IAVG +P +P + G +E ISSD
Sbjct: 110 TASFLSENRILIKGTKDNNNKDNGPLNEEILEGRNILIAVGNKPVFPPVKG-IENTISSD 168
Query: 191 DIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEM 249
+ F++ K +VG+GYI +E + LG + + R LR FD+ + + ++M
Sbjct: 169 EFFNIKESK-KIGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDM 227
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
++ + + ++K+ L + E FD V+ GR T+ L LE
Sbjct: 228 KKNNINIVTFADVVEIKKVSDKNLSIHLSDGRIYEH----FDHVIYCVGRSPDTENLKLE 283
Query: 310 AAGV--------------TCVSN--------SGKIIAETEQTNVSNIYAVGDVLEGKP-- 345
V T V+N K E E N+ +Y L K
Sbjct: 284 KLNVETNNNYIVVDENQRTSVNNIYAVGDCCMVKKSKEIEDLNLLKLYNEERYLNKKENV 343
Query: 346 --------ELTPVAIHAGRLLARRMFAGATQPMDYDNVATTVFTPLEYGCVGLSEETALA 397
+LTPVAI+AGRLLA R+F T+ +Y + T +F+ G +GLSEE A+
Sbjct: 344 TEDIFYNVQLTPVAINAGRLLADRLFLKKTRKTNYKLIPTVIFSHPPIGTIGLSEEAAIQ 403
Query: 398 RHGADKVEVYHAFYKPTEFFIPQRNI-----RNCYLKAVALREAPQRILGLHFVGPVAGE 452
+G + V++Y + K T F +I YLK V + + + I GLH +G A E
Sbjct: 404 IYGKENVKIYES--KFTNLFFSVYDIEPELKEKTYLKLVCVGK-DELIKGLHIIGLNADE 460
Query: 453 VIQGFAAAVK 462
++QGFA A+K
Sbjct: 461 IVQGFAVALK 470
>UniRef50_A6GLK6 Cluster: Glutathione reductase; n=1; Limnobacter
sp. MED105|Rep: Glutathione reductase - Limnobacter sp.
MED105
Length = 453
Score = 192 bits (467), Expect = 2e-47
Identities = 146/441 (33%), Positives = 218/441 (49%), Gaps = 40/441 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIGGGSGG+A A+ A + GAKV +++ LGGTCV GC+PKKLM
Sbjct: 8 YDLVVIGGGSGGVASARRAASYGAKVALIESSR---------LGGTCVIRGCVPKKLMMY 58
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA G+++ E + GW+V + W A A I + + L ++ + G
Sbjct: 59 AAQFGQTLREGLQPGWQVTQAEFSMAQWQA---AKGKEIDRLEGIYARMLENSGVETIRG 115
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
G K T + ++ + + I+IA G P+ PG +E +S+++ L P
Sbjct: 116 HGVIKS-----TTEVHVGERVLNTQRILIASGAAPNRSAFPG-LELAATSNELLDLSTLP 169
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGV-VFH 257
+ V+GAGYI LE A L LG +V R +PLRGFD+ + + + M+ +G+ +F
Sbjct: 170 KRVGVIGAGYIALEFACILRGLGSEVSVFYRGDLPLRGFDEGIRNRLVTAMQLQGIQLFP 229
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ ++ T L+ N FD VL ATGR T+ L LE G+
Sbjct: 230 DTDFKSLSQQGATFDLQTAAAN--------HAFDFVLNATGRSPNTQGLGLENIGLR-TG 280
Query: 318 NSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+G+I + + T + +YAVGDV + LTPVAI GR LA F G +D+ +V
Sbjct: 281 PAGEIEVNKYSHTGIKGVYAVGDV-TNRVNLTPVAIAEGRALAENEFNGKDLTVDHTSVP 339
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKP--TEFFIPQRNIRNCYLKAVALR 434
T FT G VGL+EE A R VY + P T+F + Y+K + +
Sbjct: 340 TATFTSPPIGSVGLTEEQAAKR---APTRVYETEFTPMKTKF---SGGEQKTYMK-LLVD 392
Query: 435 EAPQRILGLHFVGPVAGEVIQ 455
+A R++G+H +G + E+IQ
Sbjct: 393 DASDRVVGIHMLGEDSPEMIQ 413
>UniRef50_Q072K0 Cluster: Glutathione reductase; n=2;
Papilionoideae|Rep: Glutathione reductase - Vigna
unguiculata (Cowpea)
Length = 518
Score = 182 bits (443), Expect = 2e-44
Identities = 140/448 (31%), Positives = 216/448 (48%), Gaps = 48/448 (10%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTV--LDYVTPSPQGTKWGLGGTCVNVGCIPKK 75
YD+DL IG GSGG+ A+ A N GA V + L + T + + T G+GGTCV GC+PKK
Sbjct: 65 YDFDLFTIGAGSGGVRAARFAANNGASVAICELPFSTVASE-TTGGVGGTCVIRGCVPKK 123
Query: 76 LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKID 135
L+ A+ E+ +GW S K +W +L ++ + + + L +
Sbjct: 124 LLVYASKFSHEFEESHGFGWSYDS--EPKHDWSSLIANKNAELQRLTGIYKNILNNAGVK 181
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSL 195
+ G G+ DAHT+ NG K+ +AK+I+++VGGRP PDIPG EY I SD L
Sbjct: 182 LIEGHGKIIDAHTVDV---NG--KQYSAKHILVSVGGRPFIPDIPGK-EYAIDSDIALDL 235
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGV 254
PGK +VG GYI LE AG N L + +R LRGFD+++ V +M +G+
Sbjct: 236 PSQPGKIAIVGGGYIALEFAGIFNGLKSDVHLFIRQKKVLRGFDEEIRDFVGEQMSLRGI 295
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
+ S TG+ + +N + G + + Y+ T ++ A G
Sbjct: 296 TMNG----FSHIMFATGR-RPNTKNLGLESAGVKLAKDGSIEVDEYSQTSVPSIWAVG-- 348
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ TN N+ V + AG ++ T+P DY
Sbjct: 349 ------------DVTNRINLTPV------------ALMEAGAIVKTLFQDNPTKP-DYRT 383
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V + VF+ G VGL+EE A+ ++G ++++ A ++P + + R ++K V
Sbjct: 384 VPSAVFSQPPIGQVGLTEEQAVQQYG--DIDIFTADFRPLKSTLSGLPDR-VFMKVVVSA 440
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ++LGLH G A E+IQGFA A+K
Sbjct: 441 KT-NKVLGLHMCGEDAPEIIQGFAIAIK 467
>UniRef50_Q59299 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Clostridium|Rep: Dihydrolipoyl dehydrogenase -
Clostridium magnum
Length = 578
Score = 176 bits (429), Expect = 9e-43
Identities = 141/447 (31%), Positives = 225/447 (50%), Gaps = 29/447 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMHQ 79
+L VIGGG GG A A LGAKVT+++ K LGGTC+NVGCIP K L+H
Sbjct: 117 NLVVIGGGPGGYVAAIRAAQLGAKVTLIE---------KESLGGTCLNVGCIPTKVLLHS 167
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKS-VNWVTRVDLREKKIDYVN 138
+ LL E + E G ++ +I +NW + + + IK V+ V+ + L K+ +
Sbjct: 168 SQLLTE-MKEGDKLGIDIEG--SIVVNWKHIQKRKKIVIKKLVSGVSGL-LTCNKVKVIK 223
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG-AVEYCISSDDIFSLGH 197
G +F+ T++ T ++G +++ N +IA G P P+I G + I S SL
Sbjct: 224 GTAKFESKDTILVTKEDGVAEKVNFDNAIIATGSMPFIPEIEGNKLSGVIDSTGALSLES 283
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKGVV 255
P ++G G IG+E A NSLG ++ + +P L D+++++ +++ + G+
Sbjct: 284 NPESIAIIGGGVIGVEFASIFNSLGCKVSI-IEMLPHILPPMDREISEIAKAKLIRDGIN 342
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
+N C +E+ E G LK + + +E DV + VL+A GR + + L++E GV
Sbjct: 343 INNNCKVTRIEQGEDG-LKVSFIGDKGEE-SIDV-EKVLIAVGRRSNIEGLDVEKIGVKT 399
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
S I+ + +TNV IYA+GD GK L VA G ++A G + MDY V
Sbjct: 400 EGGS-IIVNDKMETNVEGIYAIGD-CTGKIMLAHVASDQG-VVAAENIMGQNKKMDYKTV 456
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
V+T E VGL+EE A + KV + + N +K + ++
Sbjct: 457 PACVYTKPELASVGLTEEQAKEKGIDYKVGKFQLAANGKSLIM---NETGGVIKIITDKK 513
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ILG+H +GP A ++I A A++
Sbjct: 514 Y-EEILGVHILGPRATDLITEAALALR 539
>UniRef50_Q0US44 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 432
Score = 175 bits (425), Expect = 3e-42
Identities = 117/365 (32%), Positives = 186/365 (50%), Gaps = 21/365 (5%)
Query: 102 AIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEI 161
A + +WP + ++K +N + +L + +I++ G +F + L +G + I
Sbjct: 46 APEFDWPYFKKKRDAYVKRLNGIYENNLNKDEIEHFRGRAKFVGKDEVEVDLHDGGVQRI 105
Query: 162 TAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSL 221
AK+I+IA GGRP P+IPG E CISSD F L P GAGYIG+E G L++L
Sbjct: 106 KAKHILIATGGRPKLPEIPGK-ELCISSDGFFDLEKLPKSIATSGAGYIGVEMTGMLHAL 164
Query: 222 GYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNT 280
G +R LR FD + AVT E E++G+ N + K K +
Sbjct: 165 GSKTHFFIRGDKLLRTFDPMIQDAVTKEYERQGI---NLYKGSQITK------KPSRRKE 215
Query: 281 ETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDV 340
T E E + ++ KT ++ G+ + + + + T++ NIYA+GDV
Sbjct: 216 STVEVEEGPYSRLVAC----LKLKTSKIKDFGIKLNDKNHIVTDDYQNTSLPNIYAIGDV 271
Query: 341 LEGKPELTPVAIHAGRLLARRMFAGATQP-MDYDNVATTVFTPLEYGCVGLSEETALARH 399
+ ELTPVAI AGR L+ R+F + Y+N+ + VF+ E G +GL+E A +H
Sbjct: 272 CDRGFELTPVAIAAGRRLSDRLFGNQPDARLVYENIPSVVFSHPEIGSIGLTEPEAREKH 331
Query: 400 GADKVEVYHAFYKPTEFFI--PQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGF 457
G D+V+VY + F + P+ Y K V + + ++++GLH +G + E++QGF
Sbjct: 332 G-DQVKVYKTEFSGMYFAMMDPEHKQPTAY-KIVCIGK-EEKVVGLHILGQASSEILQGF 388
Query: 458 AAAVK 462
A+K
Sbjct: 389 GVAIK 393
>UniRef50_Q6ARJ3 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Desulfotalea psychrophila|Rep: Dihydrolipoyl
dehydrogenase - Desulfotalea psychrophila
Length = 479
Score = 168 bits (408), Expect = 3e-40
Identities = 131/447 (29%), Positives = 207/447 (46%), Gaps = 21/447 (4%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQAA 81
+ V+G G GG A A LG VTV++ K +GGTC+N GCIP K+ Q+A
Sbjct: 10 IVVLGAGPGGYVAAIRAAQLGGDVTVIE---------KENVGGTCLNWGCIPSKIYKQSA 60
Query: 82 LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGLG 141
SI ++ ++ + + K+N L E + I S + L + I Y+ G
Sbjct: 61 DTLNSIKDSASFC--IDGISEGKLNLERLQERTKGIIASQSKGIHGLLAKNSISYIGGEA 118
Query: 142 EFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLGHPPG 200
+ +H+L T K+G +E+ ++IA G P P +P + +SSD IFSL P
Sbjct: 119 KMSGSHSLSVTRKDGETEEVQFDKLIIATGSTPMALPFLPFDGDRILSSDHIFSLKEIPE 178
Query: 201 KTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
++G G IG E A L S G T+ L R +PL +++ ++ + EM++K +
Sbjct: 179 SITIIGGGVIGCEFACILQSFGVEVTLVEGLERLLPLPSVEEECSKLLLREMKKKKIKVE 238
Query: 258 NKCVPLSV-EKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVTC 315
K S +K QL Q E+ + + + VL+ GR A + +L+L+ AGV
Sbjct: 239 LKTTLASASQKNGMVQLNLVSQGKNGTEKAKQIESEKVLVCIGRRASSASLDLDQAGVET 298
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVL-EGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
QT V +IYA+GDVL + L A + A F GA + M++
Sbjct: 299 TKRGWISTGANLQTTVPHIYAIGDVLGPERIMLAHTASTEAEIAAENCFGGA-EEMNWQV 357
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
+ + +FT E GCVGLSE A +G + + + ++ + K V +
Sbjct: 358 MPSAIFTMPEIGCVGLSEAQAAELYGKENIRAESSLFRTLGKAQVIGELAG-VTKIVCAK 416
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAV 461
E +ILG+H G A +++ AV
Sbjct: 417 E-DGKILGIHIAGAHATDLLGEATLAV 442
>UniRef50_A3GI90 Cluster: Glutathione reductase; n=1; Pichia
stipitis|Rep: Glutathione reductase - Pichia stipitis
(Yeast)
Length = 475
Score = 166 bits (404), Expect = 9e-40
Identities = 133/466 (28%), Positives = 216/466 (46%), Gaps = 42/466 (9%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YDL V+G G G A A G +V + V P +GGTC+NVGCIPKK+M
Sbjct: 4 NYDLIVLGSGPAGAIAALAAAKFGKRVAI---VCPR-------IGGTCINVGCIPKKIMW 53
Query: 79 QAALLGESIHEAVAYGWEVP--SLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
+AA L +++ A +G P +++ INW L +N + ++ +D
Sbjct: 54 EAASLSKAMPYAPYFGIRKPVSTVEYGDINWDVLASKRDEVTGRINTHYEQEYADQGVDV 113
Query: 137 VNGLGEF--KDAHTLIA---------TLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY 185
+ G G+F ++A ++ T K K +++A ++IAVG + P E
Sbjct: 114 IYGYGKFINEEADIQVSLLGQTIRGKTYKKDDKLDLSASYVIIAVGNQAVIPQNVLGAEL 173
Query: 186 CISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQA 244
SD FS P +VG GYIG E A L+ G TV+ + + L FD + +
Sbjct: 174 GGISDTFFSWHEQPRTVAIVGGGYIGTELAQMLSIFGTKVTVITKGNSLLTRFDDSIQER 233
Query: 245 VTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTK 304
+T+ +++ GV L++++L+ + T Q ++V+ A GR
Sbjct: 234 LTAALKEDGVEIVTNATVLAIKQLDNLKEVKISNGTSLQ------VESVIWAIGRKPQI- 286
Query: 305 TLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFA 364
L +A + + II + QT +YA GD++ K LTPV + G ++R +F
Sbjct: 287 NLGYSSANIKLGDSGEVIIDDFHQTTNLKVYASGDII-NKINLTPVGLQTGARISRHLFG 345
Query: 365 -GATQPMDYDN-----VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFI 418
DYD + +F+ E +GLS + A + G D V+VY + P+ F+I
Sbjct: 346 KKKIAKYDYDQPYPSAIPAVIFSHPEVATLGLSSKEAEDKFGKDNVKVYEQAF-PSLFYI 404
Query: 419 --PQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
PQ + Y K + + ++I+GLH +G E IQG+ A+K
Sbjct: 405 VAPQDKQKKNYYKYITAGK-DEKIVGLHLIGDNVTEEIQGYVLALK 449
>UniRef50_A5UXL4 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Chloroflexi (class)|Rep: Dihydrolipoamide dehydrogenase
- Roseiflexus sp. RS-1
Length = 471
Score = 166 bits (403), Expect = 1e-39
Identities = 134/442 (30%), Positives = 206/442 (46%), Gaps = 28/442 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
YD+ VIGGG GG A A LG K V++ + +GG C+NVGCIP K L+H
Sbjct: 6 YDVIVIGGGPGGYVAAIRAAQLGLKTAVVE---------RQAMGGVCLNVGCIPTKALLH 56
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A LL E + EA +G V + + ++W A +K++ +++ KID VN
Sbjct: 57 TADLLDE-LREAKRFGVIV---EGVSLDWEATLRQKDTVVKTMTSGVSFLMKKNKIDVVN 112
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAV---EYCISSDDIFSL 195
G + + G + +TAK+I+IAVG RP GAV + +SS ++
Sbjct: 113 GSARLAGRGQVAVSSPEGQHRTLTAKHIIIAVGARPREIPAIGAVFDNDRILSSTGGLNI 172
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEMEQK 252
P LVVGAG IG+E A + G T+ L R VPL D++++ + + ++
Sbjct: 173 PTVPKSLLVVGAGAIGVEFASMYRAFGAEVTLVEMLPRVVPLE--DEEVSAELARALNRR 230
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
G+ ++EK++ G + AR + + E F+ L+ G T + LE G
Sbjct: 231 GIKIFAGAKLNNLEKVDGGVM-ARLVDVQGAEHAL-TFERALVGVGIVPNTSDIGLEEVG 288
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
V + + +TNV IYA+GD P L A G + A + TQP+DY
Sbjct: 289 VALDPRGFIKVDDHMRTNVEGIYAIGDCATTTPWLAHKASAEGIVAAETIAGHHTQPLDY 348
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
+ + E VGL+E A G D AF + I + R ++K VA
Sbjct: 349 GKIPACTYCNPEIASVGLTEAKA-REQGYDVKVGKFAFTGNGKATILGQ--RQGFVKIVA 405
Query: 433 LREAPQRILGLHFVGPVAGEVI 454
++ + +LG+H +GP E+I
Sbjct: 406 DKQYDE-VLGIHMIGPRVTELI 426
>UniRef50_P16171 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II)
reductase); n=46; Bacteria|Rep: Mercuric reductase (EC
1.16.1.1) (Hg(II) reductase) - Bacillus cereus
Length = 631
Score = 166 bits (403), Expect = 1e-39
Identities = 139/452 (30%), Positives = 221/452 (48%), Gaps = 32/452 (7%)
Query: 16 GTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK 75
G YDYD +IG G + A EAV L AKV +++ +GT +GGTCVNVGC+P K
Sbjct: 166 GNYDYDYIIIGSGGAAFSSAIEAVALNAKVAMIE------RGT---VGGTCVNVGCVPSK 216
Query: 76 LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK-I 134
+ +A GE H A + A ++ L + + + + V+L +
Sbjct: 217 TLLRA---GEINHLAKNNPFVGLHTSASNVDLAPLVKQKNDLVTEMRNEKYVNLIDDYGF 273
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISSDDI 192
+ + G +F + +T+ NG+ +ITAK +IA G P+IPG V+Y ++S +
Sbjct: 274 ELIKGESKFVNENTVEV---NGN--QITAKRFLIATGASSTAPNIPGLDEVDY-LTSTSL 327
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPL-RGFDQQMAQAVTSEMEQ 251
L P + V+G+GYIG+E ++LG T++ RS L + +D ++++A+T + +
Sbjct: 328 LELKKVPNRLTVIGSGYIGMELGQLFHNLGSEVTLIQRSERLLKEYDPEISEAITKALTE 387
Query: 252 KGVVFHNKCVPLSVEKLET-GQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
+G+ N + E++E G +K ++R + + +L+ATGR + +LNL A
Sbjct: 388 QGI---NLVTGATYERVEQDGDIKKVHVEINGKKRIIEA-EQLLIATGRKPIQTSLNLHA 443
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
AGV S +I + +T S IY+ GDV G P+ VA + G L AR G Q +
Sbjct: 444 AGVEVGSRGEIVIDDYLKTTNSRIYSAGDVTPG-PQFVYVAAYEGGLAARNAIGGLNQKV 502
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
+ + V FT VGL+E+ A + K V P + R + K
Sbjct: 503 NLEVVPGVTFTSPSIATVGLTEQQAKEKGYEVKTSVLPLDAVPRA--LVNRETTGVF-KL 559
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
VA + ++LG H V AG+VI AVK
Sbjct: 560 VADAKT-LKVLGAHVVAENAGDVIYAATLAVK 590
>UniRef50_Q3VU31 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation
region; n=2; Chlorobiaceae|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Prosthecochloris aestuarii DSM 271
Length = 495
Score = 164 bits (399), Expect = 4e-39
Identities = 135/450 (30%), Positives = 209/450 (46%), Gaps = 24/450 (5%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
YDYD+ VIGGG+ GL A A +LGAK +++ + LGG C GCIP K +
Sbjct: 3 YDYDVTVIGGGAAGLTAAGVAASLGAKTALVE---------EKKLGGDCTWYGCIPSKTL 53
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSV-NWVTRVDLREKK-ID 135
+AA +I A +G E I IN+ + V + + ++ EK +
Sbjct: 54 LKAAKAAHTIRHAARFGIETHG--EISINFETVMRRVHEVQQQIYQEADAPEIYEKMGVT 111
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIF 193
+ G F D HT+ + +KN++IA G RP P IPG V Y ++++ +F
Sbjct: 112 VLYGKAAFVDEHTITIETGQSGISTLQSKNVIIATGSRPITPPIPGLEKVSY-VTNEQLF 170
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSE-MEQK 252
SL P + L++GAG IG+E LG V + D A+ + +EQ+
Sbjct: 171 SLKKQPRQLLILGAGPIGIEMGQAFCRLGSKVHVFDAEEHILPKDHPELTAILQKVLEQE 230
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
G+ FH + V++++ G + + T + D +L+A GR A T+ LNLEAAG
Sbjct: 231 GMTFHLQYRVTQVDEMD-GIITVTAEEETTGRTIQLTGDALLVAAGRAANTENLNLEAAG 289
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
VT G + + QT+ S+IYA GDV G + T +A H ++ A M D
Sbjct: 290 VT-THKRGITVNQYCQTSRSHIYACGDVAGGM-QFTHIAEHMAKIAAGTMLTHLPLQTDD 347
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
++ +T E VG +E ARH EVY + + I + + +++ A
Sbjct: 348 RHIPWCSYTEPEIAHVGETEAELHARHAGH--EVYRFPFNRIDRAITE-DATEGWIRIYA 404
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
E +I G +G AGE+I A++
Sbjct: 405 -AEFDGKIFGADILGAHAGELISEIGLAMR 433
>UniRef50_Q1LHF0 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=5;
Burkholderiaceae|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase - Ralstonia
metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Length = 493
Score = 163 bits (397), Expect = 7e-39
Identities = 130/456 (28%), Positives = 203/456 (44%), Gaps = 29/456 (6%)
Query: 11 KNILAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVG 70
+++ T + D VIG GSGG+A A+ A + GA+V +++ + +GGTCVN G
Sbjct: 39 RSVRPTTREADFVVIGAGSGGVAAARRAASHGARVILVE---------RDAIGGTCVNRG 89
Query: 71 CIPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLR 130
C+PKK++ A + +++ K +W + V + +N L
Sbjct: 90 CVPKKMLSYGANWASILSTCLSH-------TGGKEDWRDASVRVNAEVARLNASYAQRLN 142
Query: 131 EKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSD 190
E ++ ++G A ++ + I + +IA G P +PG E SSD
Sbjct: 143 EAGVEILHGDARLSGADEVVV-----GNEIIRTRKTLIATGAHPLALPVPGG-ELASSSD 196
Query: 191 DIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRG-FDQQMAQAVTSEM 249
D+F+ P V+G GYI +E A L+ G +LVR L FD +A A+ +
Sbjct: 197 DVFTWQTVPASIAVIGGGYIAVEMASILSRYGVKVDLLVRGDRLLPKFDHDIAAALAEAL 256
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNL 308
KGV H + +++ G + + R + V VL A GR L L
Sbjct: 257 AAKGVRLHFRA-DVTMLSQANGATEVCYTQQNNPGRTQTVRAQAVLAAIGRRPSIAELGL 315
Query: 309 EAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQ 368
+A GV G + +T V +I+A+GD ++ LTPVAI GR LA R+F
Sbjct: 316 DALGVQLGERGGICVDRQFRTTVRSIHAIGDCMDRNLHLTPVAIAQGRWLADRLFGKRGD 375
Query: 369 PMDYDNVATTVFTPLEYGCVGLSEETALARHG--ADKVEVYHAFYKPTEFFIPQRNIRNC 426
D+D V T VF+ G VGL+E A+ G AD+V + E +
Sbjct: 376 IADFDFVPTAVFSEPAIGAVGLTEAQAIEAAGGRADRVRTEIKRFVSLENRF--GGVAQP 433
Query: 427 YLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + R+LG H + A E+IQ FA A++
Sbjct: 434 SVFKLVFNARSGRVLGAHLMDNAAPEIIQTFAVALR 469
>UniRef50_Q1EVV0 Cluster: Dihydrolipoyl dehydrogenase; n=6;
Clostridium|Rep: Dihydrolipoyl dehydrogenase -
Clostridium oremlandii OhILAs
Length = 467
Score = 162 bits (393), Expect = 2e-38
Identities = 128/448 (28%), Positives = 218/448 (48%), Gaps = 31/448 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+ +IGGG GG A LG KVT+++ + LGGTC+NVGCIP K + +
Sbjct: 4 DIVIIGGGPGGYVAAIRGAQLGGKVTLIE---------ENALGGTCLNVGCIPTKALCKN 54
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
A + ++ +G + ++ I+ + E QN I + L ++ + G
Sbjct: 55 AEVISTLKNIEEFG--IKGIENYSIDVEKIQERKQNVIDQLVGGIHTVLSAYGVEILRGR 112
Query: 141 GEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSDDIFSLGHPP 199
G + + + ATL G ++EI AKNI+IA G +P P IPG + ++S+++ S P
Sbjct: 113 GTILNKNLVKATLVTGEEREIPAKNIIIATGAKPTLPPIPGIHLNGVMTSNELLSFKEIP 172
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATV--LVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
+ ++G G IG+E AG N+LG TV S+ ++ D+ +++ +T+ +++ G+ +
Sbjct: 173 KRLAIIGGGVIGIEFAGIFNALGSEVTVFEFAPSILIK-LDKDISKRLTTSLKKDGIKIN 231
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
VE+++ + + E D VL++ GR + + LNLE G+ +
Sbjct: 232 TS---TGVEEIKESNGSLVIVAKDKKGSIEVEVDQVLVSVGRTPVIEGLNLEGIGIE-LD 287
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
+ + +TNV +YA+GDV G L A H G+ +A + A D V +
Sbjct: 288 RKRIQVNDRFETNVKGVYAIGDV-NGGMMLAHEASHEGKSVA-EIIMDAPVSEDRGVVPS 345
Query: 378 TVFTPLEYGCVGLSEETALARHGAD-KVE--VYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
+F E VG++EE A G D K ++ A K PQ ++K ++
Sbjct: 346 CIFISPEISTVGITEEEA-KEQGIDYKTSKFMFGANGKALSMGEPQG-----FVKVISTG 399
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
E RI+G+H +GP A ++I A A++
Sbjct: 400 E-NNRIIGVHIMGPHAADLIHEGALAIR 426
>UniRef50_Q1VLA0 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Psychroflexus torquis ATCC 700755|Rep: Dihydrolipoyl
dehydrogenase - Psychroflexus torquis ATCC 700755
Length = 432
Score = 159 bits (387), Expect = 1e-37
Identities = 115/397 (28%), Positives = 198/397 (49%), Gaps = 24/397 (6%)
Query: 62 LGGTCVNVGCIPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALT--EAVQNHIK 119
LGGTC+N GCIP K A L I + YG + +I N AL E V+ +
Sbjct: 15 LGGTCLNRGCIPAKYWLHVAELNHEISTSENYGINIEG-KSIDWNKTALKRIEVVEKLVS 73
Query: 120 SVNWVTRVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPD 178
+ + L+ K ++ + G G ++ ++++ +G+ ++I + I++A G +P + P+
Sbjct: 74 GIKLL----LKSKDVNVIEGWGSIENKNSVLVKKSDGTTEKIESDYIILATGSKPRNLPN 129
Query: 179 IPGAVEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGF 237
I + ++SD + PP K +VGAG IG E A LN LG ATV+ + L G
Sbjct: 130 IELDENFIVTSDSALNWEEPPKKVCIVGAGAIGCEFASLLNDLGSEATVVEMAKEILPGL 189
Query: 238 DQQMAQAVTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMAT 297
D++ + + ++ ++GV F + S+E +E + N E+ E +D VL+A
Sbjct: 190 DKRTSGELRKQLSKRGVDFK---LDSSIEAIEGNTV-----NFSDGEKKE--YDCVLIAV 239
Query: 298 GRYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRL 357
GR LT+ + LE ++ + + +T QT+V NI+A+GD++ P+L A
Sbjct: 240 GRAPLTENIGLENVNISLENGFINVDLDTFQTSVENIFALGDIVNNTPQLAHAAFAEAIS 299
Query: 358 LARRMFAGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFF 417
+ +G +P+DY+ + V+T E VGL+ E A + + + + H+F
Sbjct: 300 SVTYIASGEKKPLDYNAIPYVVYTRPELAEVGLNAEKAKSEN-IEVEQAQHSFAGVGRAM 358
Query: 418 IPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVI 454
I ++N +K A ++ P I+G GP AGE+I
Sbjct: 359 ITEQN--QGLVKVYAKKDGP--IVGASVCGPSAGEMI 391
>UniRef50_A0LAA4 Cluster: Dihydrolipoyl dehydrogenase; n=9; cellular
organisms|Rep: Dihydrolipoyl dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 468
Score = 159 bits (386), Expect = 1e-37
Identities = 131/446 (29%), Positives = 202/446 (45%), Gaps = 21/446 (4%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL VIGGG GG A A LG K +D P+ LGGTC+NVGCIP K + Q
Sbjct: 5 FDLVVIGGGPGGYVAAIRAAQLGLKTACIDK-RPT-------LGGTCLNVGCIPSKALLQ 56
Query: 80 AA-LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
++ L + H A+G E+ +K N + + Q ++ + ++ K+ ++
Sbjct: 57 SSHQLETAQHAMAAHGVEIKG---VKANLTTMMQRKQEVVQGLTQGIAFLFKKNKVTHLM 113
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGR-PHYPDIPGAVEYCISSDDIFSLGH 197
G G D+ + T +GS + +T +NI+IA G P + ++ ISS +L
Sbjct: 114 GSGTIVDSSHVQVTAADGSVQTLTTENILIASGSEVATLPGLEIDEKHIISSTGALALDK 173
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P K +V+GAG IGLE LG TV+ L G D ++ + + ++G+ F
Sbjct: 174 VPKKMVVIGAGVIGLELGSVWRRLGAEVTVVEFLDGILPGMDGEIRKTAQRTLSKQGMHF 233
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
+ L+ G +K + + E E D VL+A GR T+ L LE GVT
Sbjct: 234 KLGTKVTAASVLKNG-VKLTMEPVKGGEAEERQADVVLVAVGRRPYTQGLGLENIGVTLD 292
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ QT + ++A+GDV+ G L A G +A + AG ++YD +
Sbjct: 293 ERGFIPVDHDRQTTCAGVFAIGDVI-GGAMLAHKAEEEGSAVAEAL-AGQVAHVNYDAIP 350
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
V+T E VG SEE+ A KV + I ++K +A
Sbjct: 351 AVVYTHPEIASVGQSEESLTAAGIPYKVGKFPFMANSRARAIGD---AEGFVKILA-HAT 406
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
ILG H +GP AG++I A++
Sbjct: 407 SDAILGAHIIGPAAGDLIAEIVLAME 432
>UniRef50_A7CCD3 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2; Ralstonia
pickettii|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Ralstonia pickettii
12D
Length = 477
Score = 158 bits (383), Expect = 3e-37
Identities = 132/464 (28%), Positives = 204/464 (43%), Gaps = 41/464 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL VIG GS GLA A+ + LGA+ ++D +GGTCVN GC+PKKL+
Sbjct: 9 FDLIVIGAGSAGLAAARRSAQLGARTLLIDRAQ---------VGGTCVNRGCVPKKLLRY 59
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A +++ + + +A W + + ++ V L + + +++G
Sbjct: 60 GAAWSQTMARCLLAAHTSDASEA----WADAIARTRAEVARLHEAHVVQLADAGVQWLSG 115
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
+ + + ++G K + A+ IV+A G RP +PGA E +SDD+F P
Sbjct: 116 MASLRGRGIVRVQAESG-KTTLRARQIVLAAGARPTPLPVPGA-ELACTSDDVFGWDTLP 173
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVFHN 258
++ G G I +E A L G TVL R L FD +A+A + GV +
Sbjct: 174 ASLIIAGGGVIAVEMASTLARFGVRVTVLTRDARVLPEFDATVAEAAAQSLAGCGV---D 230
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDV-----FDTVLMATGRYALTKTLNLEAAGV 313
+ V ++E + G DV +L A GR + L LEAAGV
Sbjct: 231 LILNADVVRVERDAVNGGGVAVYASAEGSDVPRVLRAQRMLSAIGRTSNIAGLGLEAAGV 290
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKP-ELTPVAIHAGRLLARRMFAGATQPMDY 372
T ++ + +T ++AVGDV G P +LTPVA+ GR +A R+F + D
Sbjct: 291 TLDAHGRIAVDRHFRTRARGVHAVGDVCGGSPLQLTPVAVAQGRYVAERLFGKGIKLPDM 350
Query: 373 DNVATTVFTPLEYGCVGLSEETA------LARHG--------ADKVEVYHAFYKPTEFFI 418
+ V VF VGL+E A L + G AD+++V + E
Sbjct: 351 NTVPMAVFCDPAIASVGLTEADARTRWPELGKRGPDTDKRALADRIDVVVRRFVSLEQRF 410
Query: 419 PQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + L + R+LG H V A E+IQ A AV+
Sbjct: 411 AGSGMES--LIKLVCNARSGRVLGAHIVDNAAPEIIQALAVAVR 452
>UniRef50_P09622 Cluster: Dihydrolipoyl dehydrogenase, mitochondrial
precursor; n=183; cellular organisms|Rep: Dihydrolipoyl
dehydrogenase, mitochondrial precursor - Homo sapiens
(Human)
Length = 509
Score = 158 bits (383), Expect = 3e-37
Identities = 130/452 (28%), Positives = 205/452 (45%), Gaps = 28/452 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
D D+ VIG G GG A +A LG K ++ LGGTC+NVGCIP K
Sbjct: 41 DADVTVIGSGPGGYVAAIKAAQLGFKTVCIE--------KNETLGGTCLNVGCIPSK--- 89
Query: 79 QAALLGESIHEAVAYGWEVPS----LDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKI 134
ALL S + +A+G + S + +++N + E +K++ ++ K+
Sbjct: 90 --ALLNNSHYYHMAHGTDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKV 147
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGR-PHYPDIPGAVEYCISSDDIF 193
+VNG G+ + + AT +G + I KNI+IA G +P I + +SS
Sbjct: 148 VHVNGYGKITGKNQVTATKADGGTQVIDTKNILIATGSEVTPFPGITIDEDTIVSSTGAL 207
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL--VRSVPLRGFDQQMAQAVTSEMEQ 251
SL P K +V+GAG IG+E LG T + + V G D ++++ +++
Sbjct: 208 SLKKVPEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQK 267
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
+G F K G++ + + D +L+ GR TK L LE
Sbjct: 268 QGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEEL 327
Query: 312 GVTCVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
G+ + G+I T QT + NIYA+GDV+ G P L A G + M GA +
Sbjct: 328 GIE-LDPRGRIPVNTRFQTKIPNIYAIGDVVAG-PMLAHKAEDEGIICVEGMAGGAVH-I 384
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
DY+ V + ++T E VG SEE L G + F + + N +
Sbjct: 385 DYNCVPSVIYTHPEVAWVGKSEE-QLKEEGIEYKVGKFPFAANSR---AKTNADTDGMVK 440
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ +++ R+LG H +GP AGE++ A A++
Sbjct: 441 ILGQKSTDRVLGAHILGPGAGEMVNEAALALE 472
>UniRef50_O34324 Cluster: Dihydrolipoyl dehydrogenase; n=13;
Bacillus|Rep: Dihydrolipoyl dehydrogenase - Bacillus
subtilis
Length = 458
Score = 158 bits (383), Expect = 3e-37
Identities = 134/445 (30%), Positives = 215/445 (48%), Gaps = 32/445 (7%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQAA 81
LA+IGGG G A A A G V ++D K LGGTC+N GCIP K + ++A
Sbjct: 3 LAIIGGGPAGYAAAVSAAQQGRNVLLID---------KGKLGGTCLNEGCIPTKSLLESA 53
Query: 82 LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGLG 141
+ + I A ++G E+P+ AI ++W + Q + + + +++ +I V G
Sbjct: 54 NVLDKIKHADSFGIELPA-GAISVDWSKMQSRKQQVVSQLVQGVQYLMKKNQIQVVKGTA 112
Query: 142 EFKDAHTLIATLKNGSKKEI-TAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGHPP 199
F L+ +NG KEI A ++IA G P P P E+ + S D SL P
Sbjct: 113 SFLSERKLLIEGENG--KEIREADQVLIASGSEPIELPFAPFDGEWILDSKDALSLSEIP 170
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLV---RSVPLRGFDQQMAQAVTSEMEQKGVVF 256
++VG G IG E AG LG T++ R +P D+ +A+ ++E+ GV
Sbjct: 171 SSLVIVGGGVIGCEYAGLFARLGSQVTIIETADRLIPAE--DEDIARLFQEKLEEDGVEV 228
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
H + +++ A W++ + + + + D VL+A GR L LE AGV
Sbjct: 229 HTSS---RLGRVDQTAKTAIWKSGQREFKTK--ADYVLVAIGRKPRLDGLQLEQAGVD-F 282
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
S G + QTNV +IYA GD + G +L A H G ++A +G ++ +V
Sbjct: 283 SPKGIPVNGHMQTNVPHIYACGDAI-GGIQLAHAAFHEG-IIAASHASGRDVKINEKHVP 340
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
++T E C+G++E A + +G K+ + +F + I Q+ +K +A E
Sbjct: 341 RCIYTSPEIACIGMTERQARSIYGDVKIGEF-SFSANGKALIKQQ--AEGKVKIMAEPEF 397
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAV 461
+ I+G+ +GP E+I G AAA+
Sbjct: 398 GE-IVGVSMIGPDVTELI-GQAAAI 420
>UniRef50_Q1PWS8 Cluster: Similar to NAD(P) oxidoreductase,
FAD-containing subunit; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to NAD(P) oxidoreductase,
FAD-containing subunit - Candidatus Kuenenia
stuttgartiensis
Length = 472
Score = 155 bits (377), Expect = 2e-36
Identities = 136/453 (30%), Positives = 212/453 (46%), Gaps = 39/453 (8%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
YDY + VIG GSGGL A A +LGA+V +++ +GG C+N GC+P K
Sbjct: 3 YDYHIIVIGAGSGGLVVASGAASLGARVALIEAEK---------MGGDCLNAGCVPSKTF 53
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVN-WVTRVDLREKKIDY 136
++A + ++I +A YG + D K++ + + V I+ + +R +D
Sbjct: 54 LKSAHIAKAIRDASMYGL---TADLKKVDITTVMDRVNKVIREIEPHDSRERYEGLGVDV 110
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSD-DIFSL 195
+ G GE +D HT+ K G++ IT K IVIA G P P I G E ++ IF L
Sbjct: 111 ILGFGELQDRHTV----KIGNET-ITGKYIVIATGSEPAVPPIHGLNEVNYQTNRTIFHL 165
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPL-RGFDQQMAQAVTSEMEQKGV 254
PG +V+G+G IG+E LG T++ RS L + D ++ + +++ G+
Sbjct: 166 KELPGHLIVLGSGPIGIELGQGFRHLGSQVTIINRSPGLFKKDDPEVGPLMEKQLKDDGI 225
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVF---DTVLMATGRYALTKTLNLEAA 311
+ L + E Q + + E + G+ D +L+ATGR TK L L+
Sbjct: 226 E-----LLLGIAYREVRQ-DSDVISVEIEHEGKGRIITGDQLLVATGRLPATKNLGLDKV 279
Query: 312 GVTCVSNSGKIIAETEQ-TNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
GV V G I+ + +Q T+V NIYA GDV G + T +A + ++ R + +
Sbjct: 280 GVR-VDEKGYIVTDKKQKTSVKNIYACGDV-TGHYQFTHMAGYQAGIIIRNIIFKLCAKV 337
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
DY V T +T E VG +E A K Y + K I + + +
Sbjct: 338 DYSAVPWTTYTKPEVAHVGYTEPM------ASKAGTYKSSLKVDLSAIDRAKAEDDRVGF 391
Query: 431 VALREAPQ-RILGLHFVGPVAGEVIQGFAAAVK 462
+ L + RI+G VG AGE+I A+K
Sbjct: 392 LKLNLGKKGRIIGATLVGEKAGEMIPAITIAIK 424
>UniRef50_A1SH76 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=10; Bacteria|Rep:
Pyridine nucleotide-disulphide oxidoreductase
dimerisation region - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 450
Score = 155 bits (377), Expect = 2e-36
Identities = 134/448 (29%), Positives = 196/448 (43%), Gaps = 33/448 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL V+G G G+A A + + G +V ++D + GGTC GC PKK++ +
Sbjct: 5 YDLVVVGAGMAGVAAANKCASSGWRVAIVDALP---------YGGTCALRGCDPKKILRR 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + + G + L +I+W L + V DL ++ ++G
Sbjct: 56 GAEIIDGARLMRGKGIDGQGL---RIDWADLMRHKRGFTDPVPDNLERDLAGHGVETLHG 112
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
F +T+ G+ E +++ ++A G RP PG E+ I S D L P
Sbjct: 113 NARFLGGNTVEIA---GASVE--SRHFLVATGARPRALAFPGH-EHLIDSTDFLDLERLP 166
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFHN 258
+ L VG G+I E A G TV+ R PLRGFD + + Q G+
Sbjct: 167 ARILFVGGGFISFEFAHIATRAGSATTVVDRGPRPLRGFDPDLVDLLLGRSRQAGIAVRP 226
Query: 259 KCVPLSVEKLETGQLKARWQNT-ETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVTCV 316
++ K + G +Q T ET E E + D V+ GR A L+LEAAGV
Sbjct: 227 ATTVTAIAKDKAG-----YQVTLETPEGSETIECDLVVHGAGREADLAGLDLEAAGVEWS 281
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLE--GKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
++ + T +YA GD + G P LTPVA+ GR+ A M G T+ DY
Sbjct: 282 PRGVRVAGHLQSTTNPAVYAAGDSADTPGMP-LTPVAVFEGRVAASNMVNGTTRAPDYAG 340
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V T VFT E VGL E A R G D V+V F + ++ R + +
Sbjct: 341 VPTAVFTIPELARVGLLEREARER-GLD-VDV--RFNDTSGWYSNYRTGETTAAAKILVD 396
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
A R++G H +GP E+I A+K
Sbjct: 397 RATDRVVGAHLLGPEYAELINVLGLAIK 424
>UniRef50_Q0LM28 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Herpetosiphon aurantiacus ATCC 23779
Length = 472
Score = 154 bits (373), Expect = 5e-36
Identities = 135/445 (30%), Positives = 208/445 (46%), Gaps = 28/445 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
DL VIGGGS G+ AK +LGAK+TV+ + K LGG C GC+P K + A
Sbjct: 3 DLLVIGGGSAGITFAKFGASLGAKITVI-------EANK--LGGDCTWTGCVPSKSLIHA 53
Query: 81 ALLGESIHEAVAYGWEV-PSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + + A YG PS+D + +VQ I + V LR+ + G
Sbjct: 54 AKIAHTTATAARYGISAQPSIDFAAV--MGYVHSVQQQIYQHDDAPEV-LRQAGARVIEG 110
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLGHP 198
F D T+ NG + + AK+ IA G P P IPG E ++++D+F L
Sbjct: 111 RARFYDDQTVEV---NG--ELLRAKHFCIATGSHPKIPTIPGLAEAGYLTNEDVFLLEAL 165
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQ-MAQAVTSEMEQKGVVFH 257
P + +V+G G IG E L LG T++ + L D M A+ ++ +G+ +
Sbjct: 166 PKRIVVLGGGPIGCELGQALFRLGAEVTIIQQGPRLLPKDDHAMGAALAQALKSEGLQLY 225
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
L VE L+ G + Q Q + V D +L+A GR L L+AAG+
Sbjct: 226 LNTKTLKVE-LQAGAKQLTIQTANNQPQ-TIVADAILVAAGRTPNLHNLGLDAAGILYDP 283
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAI-HAGRLLARRMFAGATQPMDYDNVA 376
+ +T+ ++A GDV+ G+ + T VA AG +L +F G + M Y+ V
Sbjct: 284 EQRIHVDHYLRTSNPRVFACGDVI-GRYQFTHVAAQEAGLVLRNALFPGQS-AMKYELVP 341
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
FT E G VGL+E+ A A++G+ + VY + + + + K +A+
Sbjct: 342 WATFTDPEVGHVGLNEDQARAKYGS-SLRVYELPWSAND-RARTEDATQGFTKILAVGRK 399
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAV 461
Q I+G+H +G AG++I A+
Sbjct: 400 EQ-IVGVHIIGQGAGDMINAAVLAM 423
>UniRef50_Q1FMM1 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Clostridiaceae|Rep: Dihydrolipoyl dehydrogenase -
Clostridium phytofermentans ISDg
Length = 470
Score = 153 bits (372), Expect = 7e-36
Identities = 114/380 (30%), Positives = 187/380 (49%), Gaps = 21/380 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIG G GG A +A LG K V++ +GGTC+N GC+P K M
Sbjct: 5 YDLLVIGAGPGGYVAAIKAAKLGMKTAVIE---------NREVGGTCLNRGCVPAKAMLH 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA L + + +G V + + ++ + +S+ L+ K++ + G
Sbjct: 56 AAKLYQEVLSGEQFGILV---EEVSFDYGKVMSYKNETSESLRLGVEQLLKGNKVERLQG 112
Query: 140 LGEF-KDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSDDIFSLGH 197
+G KD I T K G ++ + AKNI++A G +P P I G + ++SD++F L H
Sbjct: 113 IGTLLKDGRVRIKT-KEG-EEILQAKNILLATGSKPVLPPIEGIHLPGIMTSDEMFQLDH 170
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P L++G G IG+E A +S G T+L L G D++++Q + ++++GV
Sbjct: 171 VPESLLIIGGGVIGVEFATVYSSFGSKVTLLEAEERLLPGLDKEISQNIKLLLKKRGVDI 230
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGE-DVFDTVLMATGRYALTKTLNLEAAGVTC 315
H + +EK++ + + + QE+ E +L ATGR T L LE +
Sbjct: 231 HTRAFVQKIEKVDCEFICTFLEKGKDQEKAEVRKIPYLLSATGRIPNTHGL-LEETTLLE 289
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
+ ++ E +T++ N++A+GDV+ G +L VA G RM G +D V
Sbjct: 290 MDRGRILVNENFETSMPNVFAIGDVIGGS-QLAHVASSQGICAVERM-NGKEPSIDLSVV 347
Query: 376 ATTVFTPLEYGCVGLSEETA 395
+ V+T E CVG++E+ A
Sbjct: 348 PSCVYTDPEIACVGITEQEA 367
>UniRef50_P08332 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II)
reductase); n=313; root|Rep: Mercuric reductase (EC
1.16.1.1) (Hg(II) reductase) - Shigella flexneri
Length = 564
Score = 153 bits (372), Expect = 7e-36
Identities = 133/445 (29%), Positives = 202/445 (45%), Gaps = 25/445 (5%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQAA 81
+AVIG G +A A +AV GA+VT+++ +GT +GGTCVNVGC+P K+M +AA
Sbjct: 100 IAVIGSGGAAMAAALKAVEQGARVTLIE------RGT---IGGTCVNVGCVPSKIMIRAA 150
Query: 82 LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK--IDYVNG 139
+ E+ G + I+ AL Q + + + E I ++G
Sbjct: 151 HIAHLRRESPFDGGIAATTPTIQRT--ALLAQQQARVDELRHAKYEGILEGNPAITVLHG 208
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE--YCISSDDIFSLGH 197
FKD LI L +G ++ + +IA G P P IPG + Y S++ + S
Sbjct: 209 SARFKDNRNLIVQLNDGGERVVAFDRCLIATGASPAVPPIPGLKDTPYWTSTEALVSETI 268
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P + V+G+ + LE A LG T+L RS D + +AVT+ +G+
Sbjct: 269 PK-RLAVIGSSVVALELAQAFARLGAKVTILARSTLFFREDPAIGEAVTAAFRMEGIEVR 327
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
V + G + T GE D +L+ATGR T+ L L+A GVT
Sbjct: 328 EHTQASQVAYIN-GVRDGEF--VLTTAHGELRADKLLVATGRAPNTRKLALDATGVTLTP 384
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
+I +T+V +IYA GD + +P+ VA AG A M G ++ +
Sbjct: 385 QGAIVIDPGMRTSVEHIYAAGDCTD-QPQFVYVAAAAGTRAAINM-TGGDAALNLTAMPA 442
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
VFT + VG SE A A H K + + + R ++K V + E
Sbjct: 443 VVFTDPQVATVGYSE--AEAHHDGIKTDSRTLTLDNVPRALANFDTRG-FIKLV-VEEGS 498
Query: 438 QRILGLHFVGPVAGEVIQGFAAAVK 462
R++G+ V P AGE+IQ A A++
Sbjct: 499 GRLIGVQAVAPEAGELIQTAALAIR 523
>UniRef50_Q2RZZ0 Cluster: Mercuric reductase; n=1; Salinibacter
ruber DSM 13855|Rep: Mercuric reductase - Salinibacter
ruber (strain DSM 13855)
Length = 574
Score = 152 bits (369), Expect = 2e-35
Identities = 128/455 (28%), Positives = 209/455 (45%), Gaps = 28/455 (6%)
Query: 12 NILAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGC 71
++++ T DYD+ VIGGG+GGL+ A A NLGAK +++ + LGG C GC
Sbjct: 83 SLVSMTTDYDVLVIGGGAGGLSAAGIATNLGAKTAMIE---------RDALGGDCTWTGC 133
Query: 72 IPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD--L 129
+P K + +AA + A YG S+D +++ + + V+ + V
Sbjct: 134 VPSKTLLKAATVVHQARTASKYGLTDQSVD---VDFGGVMDHVRQVRQEVYEEADAPEIF 190
Query: 130 REKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CIS 188
+ ID G F DAHT+ +GS +++T + +++A G RP P I G E ++
Sbjct: 191 EDLDIDVREGDAHFIDAHTVGVERADGSTEQVTGRYVIVAAGARPLVPPIEGLGEVDVLT 250
Query: 189 SDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTS 247
++ +F L P + +VG G IG E A LG VL + L D ++A +
Sbjct: 251 NESLFELEEQPERLAIVGGGPIGTEMAQAFARLGTEVVVLDMADRILSNDDAELAATLRE 310
Query: 248 EMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLN 307
+E++GV + + VEK+ E+G D +L+ATGR A L+
Sbjct: 311 TLEEEGVEY---VLGAQVEKVAQ---SGGTITISAGEQGPVEADALLLATGRTANVDGLH 364
Query: 308 LEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT 367
L+AAG+ + G + + +T+ ++YAVGDV G+ + T ++ H ++
Sbjct: 365 LDAAGID-YTRQGITVDDRCRTSQGHVYAVGDV-TGRYQFTHMSNHMAKVAVTNALLKVP 422
Query: 368 QPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCY 427
+D D+V +T E VG + L G E Y Y + I +
Sbjct: 423 SKIDADHVPWVTYTEPELAHVG-AHAADLDEQGV-SYETYRFPYDQLDRAITESETTG-Q 479
Query: 428 LKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+K V +ILG +G AGE+I F A++
Sbjct: 480 IK-VHATSLTGKILGASVLGERAGELITAFTIAMR 513
>UniRef50_A6WBN3 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Actinomycetales|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Kineococcus
radiotolerans SRS30216
Length = 502
Score = 152 bits (368), Expect = 2e-35
Identities = 133/448 (29%), Positives = 203/448 (45%), Gaps = 31/448 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ V+GGG G++ A A LGA+ +L+ G++ GGTCVN GC+P +++ +
Sbjct: 44 YDVVVVGGGPAGVSAAVRAAELGARTALLE-------GSR--TGGTCVNTGCVPTRVLAK 94
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD---LREKKIDY 136
A L + A YG VP ++WPA V+ ++ V + D L + +D
Sbjct: 95 TARLVREVRTAAEYGIAVPQQ---SVDWPATVARVRATVERVQ-AAKADPQRLADLGVDL 150
Query: 137 V-NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSL 195
V G F D H L + + + +++V+ VGGR +PGA E + + L
Sbjct: 151 VLEGRARFVDPHVLELA---ATGRRVRGESVVLCVGGRSRRLPLPGA-ELATYPETVLEL 206
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGV 254
P + VVGAG G + +LG +L + L D ++ AV E++GV
Sbjct: 207 PSLPRRLAVVGAGNTGSQLVTVFRALGSEVQLLDLAPRVLPTADADVSHAVRRAFEEQGV 266
Query: 255 -VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
V S+ + G + W T R E+ FD V+M+ G A L LEAAG+
Sbjct: 267 RVATGIDAVHSLRRRADGAIDLAWSQGGT--RSEEAFDAVVMSVGWPAALDGLGLEAAGI 324
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
V+ S + E +T+V +++A GD G+ L A A GAT+ +
Sbjct: 325 E-VTRSAVAVDEHLRTSVPHVFAAGDA-NGQAMLVQAAHAEAEAAATNAVLGATRRTPHL 382
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ + FT +Y VGL+E+ A AR V V F I R +LK +A
Sbjct: 383 LLPSGGFTDPDYAGVGLTEDEARARDPHCLV-VTVPFTAMERAIIDDRT--RGFLKLIAD 439
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAV 461
R +LG H VG A E++Q A+
Sbjct: 440 RRR-DVLLGAHAVGEEAVEIVQAVTTAM 466
>UniRef50_P0A0E8 Cluster: Dihydrolipoyl dehydrogenase; n=46;
Bacilli|Rep: Dihydrolipoyl dehydrogenase -
Staphylococcus aureus
Length = 468
Score = 152 bits (368), Expect = 2e-35
Identities = 129/445 (28%), Positives = 203/445 (45%), Gaps = 27/445 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMHQ 79
D VIG G GG A A LG KVT+++ K LGG C+NVGCIP K L+H
Sbjct: 11 DTIVIGAGPGGYVAAIRAAQLGQKVTIVE---------KGNLGGVCLNVGCIPSKALLHA 61
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+ E+ H V + +++ +N+ + E + + + L+ K++ V G
Sbjct: 62 SHRFVEAQHSE---NLGVIA-ESVSLNFQKVQEFKSSVVNKLTGGVEGLLKGNKVNIVKG 117
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGHP 198
F D ++L + S + KN +IA G RP P+ + I S +L
Sbjct: 118 EAYFVDNNSL-RVMDEKSAQTYNFKNAIIATGSRPIEIPNFKFG-KRVIDSTGALNLQEV 175
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVFH 257
PGK +VVG GYIG E + G T+L + L GF++QM Q V M++KGV
Sbjct: 176 PGKLVVVGGGYIGSELGTAFANFGSEVTILEGAKDILGGFEKQMTQPVKKGMKEKGVEIV 235
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ + S E+ + G +K ++ + +E+ + D VL+ GR T L LE GV
Sbjct: 236 TEAMAKSAEETDNG-VKVTYE-AKGEEKTIEA-DYVLVTVGRRPNTDELGLEELGVKFAD 292
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
+ + +T++SNIYA+GD++ G P L A + ++ A + G +DY +
Sbjct: 293 RGLLEVDKQSRTSISNIYAIGDIVPGLP-LAHKASYEAKVAAEAI-DGQAAEVDYIGMPA 350
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
FT E VG SE A A K + + N ++K + L+E
Sbjct: 351 VCFTEPELATVGYSEAQAKEEGLAIKASKFPYAANGRALSLDD---TNGFVKLITLKE-D 406
Query: 438 QRILGLHFVGPVAGEVIQGFAAAVK 462
++G VG A ++I A++
Sbjct: 407 DTLIGAQVVGTGASDIISELGLAIE 431
>UniRef50_Q5FK23 Cluster: Glutathione reductase; n=1; Lactobacillus
acidophilus|Rep: Glutathione reductase - Lactobacillus
acidophilus
Length = 443
Score = 151 bits (366), Expect = 4e-35
Identities = 115/335 (34%), Positives = 160/335 (47%), Gaps = 22/335 (6%)
Query: 63 GGTCVNVGCIPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVN 122
GGTC N GC PK M + + G + +A KI+WP L + + +
Sbjct: 38 GGTCPNTGCQPKIFMEGTVRPVLNSYYLAGKGIK----EAAKIDWPTLVARKKKIWTAFH 93
Query: 123 WVTRVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA 182
R + + D V G G HT+ K G + E KNIVI G P D+PG
Sbjct: 94 KNERKSMTSEHTDTVQGKGVITGPHTV----KVGDQ-EYEGKNIVIGTGLAPRDLDVPGN 148
Query: 183 VEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQM 241
EY I++++ F L P + +V+G GY+ +E A L + G T+L S LR FDQ+M
Sbjct: 149 -EYAITNNEFFDLDKLPKRAIVIGGGYVAMELATILQAAGAEVTILQHSDRLLRPFDQEM 207
Query: 242 AQAVTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDT--VLMATGR 299
+ ME +G+ FH P+ E + G Q T T E G D FDT V+ A GR
Sbjct: 208 VGTLKRIMEDRGIKFHLN-APVK-EIAKDGD-----QYTVTTENG-DTFDTDLVINAAGR 259
Query: 300 YALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLE-GKPELTPVAIHAGRLL 358
+ + LE G+ N G + E QTN+ +I+A GDV + G+P LTPVA +
Sbjct: 260 KPNVEGIGLEDVGIEFDPNKGIKVNEHMQTNIPSIFAAGDVADNGQPSLTPVAWVDAYHI 319
Query: 359 ARRMFAGATQPMDYDNVATTVFTPLEYGCVGLSEE 393
+ G T P+ Y VAT FT E VG+ E+
Sbjct: 320 INFVENGITDPIQYPPVATNAFTYPEIAQVGICED 354
>UniRef50_Q2JK69 Cluster: Pyridine nucleotide-disulfide
oxidoreductase; n=4; Cyanobacteria|Rep: Pyridine
nucleotide-disulfide oxidoreductase - Synechococcus sp.
(strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 532
Score = 150 bits (364), Expect = 7e-35
Identities = 134/452 (29%), Positives = 209/452 (46%), Gaps = 30/452 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ VIG G+ GL A A L AKV +++ G+ LGG C+ GC+P K +
Sbjct: 46 YDIVVIGAGAAGLVVASAAAQLKAKVLLVE-------GSD-RLGGDCLWYGCVPSKALLH 97
Query: 80 AALLGESIHEAVAYGW-EVPSLDAIKINWPALTEAVQNHIKSV-NWVTRVD-LREKKIDY 136
A I +A+A GW +P I +++ + E +++ + N D R+ ++
Sbjct: 98 VAHTVHRIRQAMAAGWVTLPGPAGISVDYLKVYEHIRSAQSYIANHADSPDRFRQLGVEL 157
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSL 195
V G F D T + +++ A+ VIA G RP P +PG E ++++ IF L
Sbjct: 158 VFAKGHFVDGRTF-----EVAGRQVQARAFVIATGSRPWVPPLPGLAEAGYLTNESIFDL 212
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV-RSVPLRGFDQQMAQAVTSEMEQKGV 254
P V+GAG +G E + L LG T++ R L D + AQ V ++ Q G+
Sbjct: 213 TRLPKSVAVIGAGPVGCELSQALARLGSEVTLIASRERILPKEDPEAAQVVQQQLTQDGI 272
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNT--ETQERGEDVF--DTVLMATGRYALTKTLNLEA 310
+ +V + + +L + N+ T G+ V + +L+A GR + L LEA
Sbjct: 273 RILTRVRATAVGQEQGAKLLSLKANSGAGTAAAGDQVIRAEEILVAAGRIPNVEGLGLEA 332
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRL-LARRMFAGATQP 369
AGV ++ A+ QT IYA GDV+ G P+ T VA + G + L +F +Q
Sbjct: 333 AGVQYTPQGIQVNAKL-QTRNPRIYACGDVI-GGPQFTHVAAYEGAVALVNALFFPLSQA 390
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
Y + +FT E VGL+E A ++G D V + F + + K
Sbjct: 391 R-YRVIPWAIFTEPELARVGLTESEARQQYGKDVVVLKQEFADVDRAQAEAAPLG--FAK 447
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ R +ILG H VG AGE+I A+
Sbjct: 448 LICRRNG--QILGAHLVGSQAGELIHEVVLAM 477
>UniRef50_O84561 Cluster: Dihydrolipoyl dehydrogenase; n=9;
Chlamydiales|Rep: Dihydrolipoyl dehydrogenase -
Chlamydia trachomatis
Length = 465
Score = 150 bits (363), Expect = 9e-35
Identities = 127/447 (28%), Positives = 203/447 (45%), Gaps = 31/447 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D VIG G GG A A G K +++ K GGTC+N GCIP K +
Sbjct: 5 FDCVVIGAGPGGYVAAITAAQAGLKTALIE---------KREAGGTCLNRGCIPSKALLA 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + I A +G V + IN+PA+ + + ++S+ +R KI +G
Sbjct: 56 GAEVVTQIRHADQFGIHV---EGFSINYPAMVQRKDSVVRSIRDGLNGLIRSNKITVFSG 112
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEY--CISSDDIFSLG 196
G + + +N S I A +I++A G P +P IP + E + S + +L
Sbjct: 113 RGSLISSTEVKILGENPSV--IKAHSIILATGSEPRAFPGIPFSAESPRILCSTGVLNLK 170
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQ-QMAQAVTSEMEQKGVV 255
P K ++G G IG E A ++LG +V+ S + + +++ + + ++G+
Sbjct: 171 EIPQKMAIIGGGVIGCEFASLFHTLGSEVSVIEASSQILALNNPDISKTMFDKFTRQGLR 230
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
F + SV +E + R T + +D VL++ GR T+ + L+ AGV C
Sbjct: 231 F---VLEASVSNIEDIGDRVRL----TINGNVEEYDYVLVSIGRRLNTENIGLDKAGVIC 283
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
T +TNV NIYA+GD+ GK +L VA H G ++A R AG + +DY V
Sbjct: 284 DERGVIPTDATMRTNVPNIYAIGDIT-GKWQLAHVASHQG-IIAARNIAGHKEEIDYSAV 341
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
+ +FT E VGLS A + KV + ++ + A+ E
Sbjct: 342 PSVIFTFPEVASVGLSPTAAQQQKIPVKVTKFP--FRAIGKAVAMGEADG--FAAIISHE 397
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
Q+ILG + +GP A +I AV+
Sbjct: 398 TTQQILGAYVIGPHASSLISEITLAVR 424
>UniRef50_P21880 Cluster: Dihydrolipoyl dehydrogenase; n=27;
Bacilli|Rep: Dihydrolipoyl dehydrogenase - Bacillus
subtilis
Length = 470
Score = 150 bits (363), Expect = 9e-35
Identities = 128/446 (28%), Positives = 208/446 (46%), Gaps = 28/446 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D VIG G GG A A LG KVTV++ T LGG C+NVGCIP K + A
Sbjct: 11 DTLVIGAGPGGYVAAIRAAQLGQKVTVVEKAT---------LGGVCLNVGCIPSKALINA 61
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
E+ + G + + + +++ + E + + + L+ K+D V G
Sbjct: 62 GHRYENAKHSDDMGI---TAENVTVDFTKVQEWKASVVNKLTGGVAGLLKGNKVDVVKGE 118
Query: 141 GEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGHPP 199
F D+++ + + S + T KN +IA G RP P+ + E ++S +L P
Sbjct: 119 AYFVDSNS-VRVMDENSAQTYTFKNAIIATGSRPIELPNFKYS-ERVLNSTGALALKEIP 176
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKG-VVFH 257
K +V+G GYIG E + G +L L GF++QM+ VT +++KG V H
Sbjct: 177 KKLVVIGGGYIGTELGTAYANFGTELVILEGGDEILPGFEKQMSSLVTRRLKKKGNVEIH 236
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ VE+ G + ++ + +E+ D D VL+ GR T L LE G+ ++
Sbjct: 237 TNAMAKGVEERPDG-VTVTFE-VKGEEKTVDA-DYVLITVGRRPNTDELGLEQVGIE-MT 292
Query: 318 NSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ G + + + +TNV NIYA+GD++EG P L A + G++ A + AG +DY +
Sbjct: 293 DRGIVKTDKQCRTNVPNIYAIGDIIEG-PPLAHKASYEGKIAAEAI-AGEPAEIDYLGIP 350
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
VF+ E VG +E A G D V F N + ++K + R+
Sbjct: 351 AVVFSEPELASVGYTEAQA-KEEGLDIVAAKFPFAANGRAL--SLNETDGFMKLIT-RKE 406
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
++G G A ++I + A++
Sbjct: 407 DGLVIGAQIAGASASDMISELSLAIE 432
>UniRef50_Q3ETT1 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacillus
thuringiensis serovar israelensis ATCC 35646|Rep:
Dihydrolipoyl dehydrogenase - Bacillus thuringiensis
serovar israelensis ATCC 35646
Length = 463
Score = 149 bits (361), Expect = 2e-34
Identities = 131/449 (29%), Positives = 205/449 (45%), Gaps = 31/449 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+ + VIG G GG A A LG +V +++ + LGG C NVGCIP K +
Sbjct: 7 EIETIVIGSGPGGYVAAIRAAQLGQQVAIIE---------RENLGGVCANVGCIPSKALI 57
Query: 79 QAALLGESIHEAVAYGWEVPSLDAI-KINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
+G EA Y ++ ++ +++ + E +K + L K+D +
Sbjct: 58 S---VGHRFEEA-KYSEDMGIFSSVVNVDFAKVQEFKNGVVKKLVDGVEGLLNSNKVDVI 113
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISSDDIFSL 195
G F DA+T+ + KN + + T KN +IA G RP +IP + I+S +L
Sbjct: 114 KGEAYFIDANTICVSNKN-AVQTYTFKNAIIATGSRP--VEIPPFEFTKRVINSTGALNL 170
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGV 254
P K +V+G GYIG E SLG T++ L GFD+QM Q + + KGV
Sbjct: 171 AEVPSKLVVIGGGYIGTELGSAYASLGSLVTIIEGGKDILTGFDKQMTQILKENLINKGV 230
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
VE++E G + +E+ D D VL+ GR T+ + E G+
Sbjct: 231 KIVVDASAKGVEEVENGVIVT--YEIGGEEKKVDA-DYVLITVGRRPNTENMGFEKIGIE 287
Query: 315 CVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
SN G + + + +TN+ NI+A+GD++ G P+L A + G++ A + AG +DY
Sbjct: 288 -FSNRGLLKIDQQCRTNLPNIFAIGDIVAG-PQLAHKAFYEGKVAAEAI-AGEFSFVDYL 344
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ FT E VG +EE A A KV V F + N +L+ +A
Sbjct: 345 AIPAVCFTTPELATVGYTEEQAKAEDMEVKV-VKFPFSANVHAMV--SNEEKGFLRLLA- 400
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
R+ ++G G A E+I A++
Sbjct: 401 RKEDGILVGAQIAGNGASEIIAEMGLAIE 429
>UniRef50_A5N930 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Clostridium kluyveri DSM 555|Rep: Dihydrolipoyl
dehydrogenase - Clostridium kluyveri DSM 555
Length = 455
Score = 149 bits (361), Expect = 2e-34
Identities = 131/448 (29%), Positives = 218/448 (48%), Gaps = 28/448 (6%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
Y YDL VIG G GG A A EA G K V++ K LGGTC+N GCIP K +
Sbjct: 3 YKYDLIVIGTGPGGSAAALEAAKSGMKTAVIE---------KDKLGGTCLNRGCIPMKAL 53
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
+A + + I E+ +G +V + ++N PAL + + I +++ + L++ K+D
Sbjct: 54 LHSAGIYQEIKESKKFGIQV---EKAELNVPALLQYKEGVINKLSYGMEMLLQKNKVDVF 110
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG-AVEYCISSDDIFSLG 196
G+ +AH +A +NG KK I A+ I+IA G P IPG ++ ++S ++ +
Sbjct: 111 YASGKIVNAHQ-VAVSENGEKKIIEAERIIIASGSSAVIPPIPGIQLKNVVTSYELLNKE 169
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVV 255
+++G G IG+E A ++ G TV+ + L D+++ + ++++GV
Sbjct: 170 DLFHHLVIIGGGVIGMEFASLYSAFGCRVTVIEAMNRVLPDMDREIGTNLKQILKKQGVD 229
Query: 256 FHNKCVPLSVEKLE-TGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
H SVEKLE T + K E ++ D VL+A GR T+ L E V
Sbjct: 230 IHTSA---SVEKLEQTQEEKILCTYREKEKLQHIEVDGVLVAIGRKPSTEGLFDENFAVE 286
Query: 315 CVSNSGKIIA-ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ GKI+ + +T+ +IYA+GDV+ G +L A + L A R G + +D
Sbjct: 287 --TEKGKILVNKYYKTSCPSIYAIGDVI-GGIQLAHAA-SSEALCAVRHIIGKEESLDVR 342
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ V+T E VG++ A G D + + + + + ++K VA
Sbjct: 343 VIPGCVYTNPEIAVVGITASQA-KETGIDVITKKYPMMANGKSVLTMQ--ERGFMKVVAE 399
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAV 461
+E ++ILG + A ++I F +A+
Sbjct: 400 KET-EKILGAQLMCARATDIISQFTSAI 426
>UniRef50_Q2S6F1 Cluster: Mercuric reductase; n=3; Bacteria|Rep:
Mercuric reductase - Salinibacter ruber (strain DSM
13855)
Length = 525
Score = 147 bits (357), Expect = 5e-34
Identities = 136/450 (30%), Positives = 199/450 (44%), Gaps = 29/450 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIG G GG A G V +L+ + +GGTCVN GC P K M
Sbjct: 55 YDLIVIGAGQGGGPLAGAVAEAGHDVALLE---------RRHVGGTCVNRGCTPTKTMIA 105
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK-IDYVN 138
+A + A YG E + ++ + + ++ + +R + EK +D +
Sbjct: 106 SARVAHLARRAGDYGVETGD---VSVDLETVRQRKRDIVGMFRSGSRSSIEEKDTLDLIE 162
Query: 139 GLGEFKDAHTLIATLK----NGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDI 192
G G F D +T+ TL +G + +TA IVI G RP P I G AV++ ++S I
Sbjct: 163 GDGRFVDPNTVEVTLNGDANDGGPRALTADRIVINTGTRPAIPPIDGLDAVDF-LTSTSI 221
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRG-FDQQMAQAVTSEMEQ 251
LG PG L++G GYIGLE G T++ R + G D +A A+ + +
Sbjct: 222 MELGAVPGHLLILGGGYIGLEFGQMFRRFGAEVTIIDRGEHVLGREDADVAGALEDILRE 281
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
G+ N+ +VE+ G + A + + R D +L+A GR T LN AA
Sbjct: 282 DGIRLLNETSMTAVEE-AGGTITAHLEGDDAPAR--ITGDELLVAAGRRPNTDALNPGAA 338
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
GV + T IYA+GDV G P T V+ R+L G + +
Sbjct: 339 GVATTEQGYVQVDARLATTADGIYAIGDV-TGGPAFTHVSYDDYRVLQDHWLHGGDRTTE 397
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAV 431
+A T+FT + G VGL+EE A +R G D V V + R +KAV
Sbjct: 398 DRLIAYTLFTDPQLGRVGLTEEQARSR-GLD-VTVAQMPMTRVARALEVDETRG-LMKAV 454
Query: 432 ALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ R+LG +G GEV+ A+
Sbjct: 455 -IDSTTNRLLGAAVLGIEGGEVMSVLQTAM 483
>UniRef50_Q41E05 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation
region; n=1; Exiguobacterium sibiricum 255-15|Rep:
FAD-dependent pyridine nucleotide-disulphide
oxidoreductase:Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Exiguobacterium
sibiricum 255-15
Length = 440
Score = 147 bits (357), Expect = 5e-34
Identities = 127/445 (28%), Positives = 195/445 (43%), Gaps = 38/445 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD VIG GS G A + G V +++ TP GGTC GC KK++
Sbjct: 4 YDCIVIGTGSAGNQAAYKFAEKGLNVAIIENFTP---------GGTCAQRGCDAKKILLT 54
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+ +++ + YG + + I+W L E + +++ TR E IDY +G
Sbjct: 55 GSEAKDAVERLLGYGLK----GLVSIDWRQLMERKNEYTRAIPEQTRNRYDEVGIDYYHG 110
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
F L+ E+ A +IA G RP +PG+ + ++S++ L P
Sbjct: 111 EPRFLSNKKLLV-----DDIELEADQFLIATGLRPRELSVPGSERF-LNSNEFLELRDVP 164
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFHNK 259
+ + +G GYI E A G T+L+RS L+ F+Q + + + G+ ++
Sbjct: 165 RRLVCIGGGYISFEFAHLARIAGSEVTILLRSGALKQFEQDLVSVLLEATQALGIKILHE 224
Query: 260 CVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+S T T G + D VL ATGR A + L LE AGV
Sbjct: 225 TEAVSYS-----------DTTLTLSDGTRLEADVVLNATGRVASIEHLQLEKAGV-IYEE 272
Query: 319 SGKIIAETEQTNVSNIYAVGDV-LEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
G + + Q++ SNIYA GDV + G P LTP A GRL A M G T+ ++ V +
Sbjct: 273 KGIHVNDYLQSSASNIYAAGDVAVSGNPALTPFAGTEGRLAACNMLEGNTRRLELLPVPS 332
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
VFT VG E +L ++ Y T + I++ + +A L
Sbjct: 333 IVFTTPNLAKVG-QTEASLKQNNTR----YRGKLIDTSSWQTNVRIKDPFARAKVLIGED 387
Query: 438 QRILGLHFVGPVAGEVIQGFAAAVK 462
+ILG HF+G A E+ F+ A++
Sbjct: 388 DQILGAHFIGVHAAELANYFSFAMQ 412
>UniRef50_Q28QN1 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=1; Jannaschia
sp. CCS1|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase - Jannaschia sp.
(strain CCS1)
Length = 438
Score = 147 bits (357), Expect = 5e-34
Identities = 129/380 (33%), Positives = 181/380 (47%), Gaps = 32/380 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D VIG GSGGL+ + A LGA+V V++ K LGGTCVN GC+PKKLM
Sbjct: 6 FDAIVIGAGSGGLSFGQTAAKLGARVAVIE---------KDRLGGTCVNRGCVPKKLMWT 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIK-INWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A + E G L+A IN H+ + VD + +D
Sbjct: 57 LAHAVKQSRELATQG----ILEAAPAINMATFRTKSDAHVNGI-----VDSFNETLDDA- 106
Query: 139 GLGEFKDAHTLIATLKNGSKKEIT-AKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
G+ F+ + + A + ++I A IV+A GGRP PDI GA E C SDDI ++
Sbjct: 107 GVAVFRGSGLISAPGEITLGEQILRADKIVVATGGRPARPDIDGA-ELCKVSDDILAMTD 165
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLV-RSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P +VVG GYIG E A L LG T++ L F + + ++ +G
Sbjct: 166 LPDSIVVVGGGYIGCEFASILAGLGVDVTLVSDGDAVLTEFSAPLQILAEANLKAQGCSV 225
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
P VE+ L+ ++ T DV D VL+ATGR L A V +
Sbjct: 226 VLNARPQRVER-SGDTLRVTLEDGSTL----DVAD-VLLATGRAPNLDVLGALAEDVN-L 278
Query: 317 SNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
S+SG+I I + T+V N++A+GD P LTPVA GR+LA +F G P+ ++
Sbjct: 279 SDSGQIDIDDGFATSVPNLFAIGDCTTRLP-LTPVATDDGRVLALNLFGGGADPVATSHI 337
Query: 376 ATTVFTPLEYGCVGLSEETA 395
ATT F VG +++ A
Sbjct: 338 ATTAFLMPPLAEVGATDDLA 357
>UniRef50_Q9WYL2 Cluster: Dihydrolipoamide dehydrogenase; n=6;
Bacteria|Rep: Dihydrolipoamide dehydrogenase -
Thermotoga maritima
Length = 449
Score = 147 bits (356), Expect = 6e-34
Identities = 127/445 (28%), Positives = 210/445 (47%), Gaps = 35/445 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD +IGGG GG CA + LG KV +++ K LGGTC N GCIP K M
Sbjct: 2 YDAVIIGGGPGGYVCAIKLAQLGKKVALVE---------KDALGGTCTNRGCIPTKAMLT 52
Query: 80 AA-LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ L+ E +A YG +V ++ + A+ + VQ + L++ ++
Sbjct: 53 VSHLMDEMKEKASKYGLKV---SGVEYDVAAIMKHVQKSVMMSRKGIEYLLKKNGVEVFK 109
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
G ++ +T++ + G K E AKN+V+A G P P ++ +SDD+F+L
Sbjct: 110 GTAVVENKNTVVVQ-ETGEKLE--AKNLVLAHGSVPSVFS-PFDIDGVWTSDDVFNLKEF 165
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKGVVFH 257
P ++VG G IG+E A F S G T++ + + + D +A+ V +++KGV
Sbjct: 166 PKSLVIVGGGVIGVEFATFFGSFGVDVTIVEIAEHILPYEDSDVAEEVKKALKRKGVKIL 225
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
K S+ K++ G + +N ET + + VL+A GR +++A GV
Sbjct: 226 EKTKISSLSKVDDG-FEVALENGETLKA-----EKVLLAAGRKPNIPE-DVKALGVKI-- 276
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
G + +TNV N+YA+GD+ G L VA++ G ++A + AG + MDY V +
Sbjct: 277 EKGVVTDSRMRTNVENVYAIGDIRSG-IMLAHVAMYEG-IVAAKNIAGEEEEMDYSAVPS 334
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
+F+ E VG+ E+ + EV + + + + + N V +
Sbjct: 335 IIFSSPEVASVGVREK------DVNPEEVVISKFPVSANGRARTMLENIGFAKVIADKKD 388
Query: 438 QRILGLHFVGPVAGEVIQGFAAAVK 462
+LG+ V P A ++I AVK
Sbjct: 389 GTVLGMSIVSPSATDMIMEGVIAVK 413
>UniRef50_Q2NDS9 Cluster: Mercuric reductase, putative; n=2;
Erythrobacter|Rep: Mercuric reductase, putative -
Erythrobacter litoralis (strain HTCC2594)
Length = 472
Score = 147 bits (355), Expect = 8e-34
Identities = 136/449 (30%), Positives = 210/449 (46%), Gaps = 39/449 (8%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+ +D+ VIGGG+ GL A G KV +++ G K +GG C+N GC+P K +
Sbjct: 3 FTHDVIVIGGGAAGLTAAGGCALFGLKVALIE-------GHK--MGGECLNNGCVPSKAL 53
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHI-KSVNWVTRVDLREKKIDY 136
AA + +G E L A + W V HI +++ + D E+ +
Sbjct: 54 ITAAKRAAEARKQKRFGVE---LAAPNVEW----SGVHTHIHRAIAEIEPHDSAERFEEM 106
Query: 137 VNGLGEFKD-AHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIF 193
G +D A + +TA IVIA G P P IPG AV Y +++++IF
Sbjct: 107 --GCEVIQDWARVTGKQSVEIGGRTLTAPRIVIATGSGPSVPPIPGLDAVPY-LTNENIF 163
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKG 253
L P +++G G IG+E A LG TV+ P+ D+ V M+++G
Sbjct: 164 DLEAQPDHLVIIGGGVIGMEMAQSFARLGSKVTVIEPGRPMGRDDEDSVAVVMEVMKKEG 223
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDT-VLMATGRYALTKTLNLEAAG 312
V F V EK+E G+ A T + GE V + +L+A GR A LE G
Sbjct: 224 VTF----VQGKAEKVE-GRNGA---ITVHVDNGEQVSGSHLLIAVGRKARVSGFGLEDLG 275
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
V + N+G + E +T+V NIYA+GD EG P LT V+ + G +A + G +DY
Sbjct: 276 VE-LGNNGIKVDERRRTSVKNIYAIGDCREG-PRLTHVSGYEGSNVALEITLGIPTKVDY 333
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
+ +T E +GL+E A + G DKV V + E I + + + ++K +
Sbjct: 334 KALPWCTYTEPEVAQIGLTEAEAKEKFG-DKVTVVKEGFDHNERAITEGDTKG-HMKVIL 391
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+++LG VG AGE++ F+ +
Sbjct: 392 ---KGKKVLGASIVGKNAGELLLPFSQTI 417
>UniRef50_Q26GG1 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Flavobacteria bacterium BBFL7|Rep: Dihydrolipoamide
dehydrogenase - Flavobacteria bacterium BBFL7
Length = 445
Score = 147 bits (355), Expect = 8e-34
Identities = 123/448 (27%), Positives = 204/448 (45%), Gaps = 34/448 (7%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
++D+ + G G+ G AKE G KV ++D GG C GC PKKL
Sbjct: 3 NFDVFIFGTGTAGQLVAKECAATGKKVGIIDIRE---------YGGVCSQRGCDPKKL-- 51
Query: 79 QAALLGESIHEAVAYGWEVPSL-DAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
LL S ++ + + A+KINW + + + T DL++K I
Sbjct: 52 ---LLASSEAFELSKNMKTDGIAGALKINWRDAFNYARRYTSDIPQNTEKDLKKKGIKCY 108
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
+G FKD+HT+I +EI A + VIA G +P IPG +Y ++S + F+L
Sbjct: 109 HGEASFKDSHTIIL-----DGEEIRADHFVIATGMQPLSLGIPGE-KYALTSGEFFNLKD 162
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVF 256
P K + VG GYIG+E L G T++ + L F+ + + E + G+
Sbjct: 163 VPEKVVFVGGGYIGMEFGHMLCRAGSKVTIIDKGDQILSPFEAFTSNLLEEESIKMGINI 222
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGED-VFDTVLMATGRYALTKTLNLEAAGVTC 315
S+EK++ + + + D VF+T GR LNL A V
Sbjct: 223 IKNAQVSSIEKIDNRYCVHYAIDDQIHQVTTDCVFNT----AGRVPSIDKLNLALANVVT 278
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
+ + ++ + T+ ++IYA GD+ LTP++ +++A + G + ++ ++
Sbjct: 279 NQDGILVNSKLQSTSQAHIYACGDISSKSLPLTPLSSIEAKVVADNL-NGKNRDLEIPSI 337
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRN-CYLKAVALR 434
++VFT + +GL+E A+A + + +H K T + + I + Y + +
Sbjct: 338 PSSVFTIPQCSGIGLTENQAVAEN-----KSFHTIEKDTSGWFNNKRINSPLYGYKIIIE 392
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ILG H VGP A E I FA A+K
Sbjct: 393 NETHKILGAHIVGPEAAEQINMFAIAMK 420
>UniRef50_Q9RRW5 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Deinococci|Rep: Dihydrolipoyl dehydrogenase -
Deinococcus radiodurans
Length = 467
Score = 146 bits (354), Expect = 1e-33
Identities = 132/449 (29%), Positives = 202/449 (44%), Gaps = 37/449 (8%)
Query: 14 LAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP 73
+ +DYD+ VIG G GG A A LG K ++ + +GG C+N+GCIP
Sbjct: 1 MTNNFDYDVLVIGAGPGGYHAAIRASQLGLKTACVE---------RGAVGGVCLNIGCIP 51
Query: 74 KK-LMHQAALLGESIHEA-VAYGWEVPSLDAIKIN-WPALTEAVQNHIKSVNWVTRVDLR 130
K L+H A + S H A + +LD ++N W + +K + +
Sbjct: 52 TKALLHAAETMQASKHAAEFGLTFSGQALDIARLNGWK------DSIVKKLTGGVSGLFK 105
Query: 131 EKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISS 189
K+ + G F D HT+ K TA NI+IA G P P + + + S
Sbjct: 106 ANKVTLLTGQASFVDDHTVQV-----GDKTYTAANIIIATGSDPAKLPGLEVDQQQIVDS 160
Query: 190 DDIFSLGHP-PGKTLVVGAGYIGLECAGFLNSLGYPATVL--VRSVPLRGFDQQMAQAVT 246
+ P P + L VG G IG E A N+LG ++ + SV + G D + +
Sbjct: 161 TGALVMPDPVPARMLCVGGGVIGFEFAQVYNNLGSQVKIIEFLPSV-IPGADADAVKEFS 219
Query: 247 SEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTL 306
M ++G+ + EK G + +N +T E+ +VFD VL+A GR T L
Sbjct: 220 KIMSRQGIEIVTQMKANRAEKKSDG-VHVELENVKTGEKTTEVFDRVLVAVGRRPRTDGL 278
Query: 307 NLEAAGVTCVSNSGKIIAETEQ-TNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG 365
N E AGVT V+ G I A+ +Q TNV +I+++GDV G P L A+ G L+A + AG
Sbjct: 279 NPEQAGVT-VTERGFIPADKQQRTNVPHIFSIGDV-AGNPMLAHKAMKEG-LVAAEVIAG 335
Query: 366 ATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRN 425
D + V+T E VGL+E A + K V+ +
Sbjct: 336 KPAEQDAVAIPGVVYTNPELAWVGLTEAEAQEKGYEVKTGVFPMSASGRAMTL---QATE 392
Query: 426 CYLKAVALREAPQRILGLHFVGPVAGEVI 454
++K V ++ +LG+H V P A +++
Sbjct: 393 GFVKMVVEKDT-DLLLGVHIVAPHASDML 420
>UniRef50_Q2RHM5 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Clostridia|Rep: Dihydrolipoyl dehydrogenase - Moorella
thermoacetica (strain ATCC 39073)
Length = 459
Score = 146 bits (354), Expect = 1e-33
Identities = 127/445 (28%), Positives = 211/445 (47%), Gaps = 28/445 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
Y +A+IGGG GG A A LGAKV V++ + LGGTC+N GCIP K +
Sbjct: 3 YQIAIIGGGPGGYVAAIRAAQLGAKVVVIE---------QDALGGTCLNRGCIPTKALLA 53
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + I A A+G +V + ++++ L +K + ++ K+D + G
Sbjct: 54 GAAMVRGIKGAAAFGIDV---EDYRVDYARLAARKDAVVKQLTGGIAYLFKKNKVDLIKG 110
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAV-EYCISSDDIFSLGHP 198
G K + +G+ + + A+NI++A G P G ++S + +
Sbjct: 111 RGFLKGPGQIEVATADGTIENLQAENIILATGSEPALIKALGYNGRTVVTSTEALAWTEV 170
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKGVVF 256
P + L++G G IG E A +LG T+ V +P L D ++++ + +++ GV
Sbjct: 171 PAELLIIGGGVIGCEFATLFATLGSKVTI-VEMMPAILPMIDSEISRRFSMLLKKTGVEI 229
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
K V++ G+++A + +T D VL++ GR T+ L LE AG+T
Sbjct: 230 KTKAQITEVKEAG-GRVQATLADGQTINA-----DKVLISIGRQFNTRGLGLEDAGITLG 283
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
++ E +T+V IYA+GDV K +L VA G L A G ++YD V
Sbjct: 284 PKGEIVVDEYLRTSVPGIYAIGDV-TNKIQLAHVASAQG-LAAVTTIMGRPTKVNYDAVP 341
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+ ++T E VGL++E A R KV V ++ + + + +K +A E+
Sbjct: 342 SCIYTLPEIAGVGLTKEAAEGR--GMKVRVGKFPFQASGKALCSGE-TDGMVKIIAEAES 398
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAV 461
R++G+ +GP A E+I A AV
Sbjct: 399 -DRVVGVFIMGPHATELIAEGALAV 422
>UniRef50_Q74A03 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Geobacter|Rep: Dihydrolipoyl dehydrogenase - Geobacter
sulfurreducens
Length = 452
Score = 146 bits (353), Expect = 1e-33
Identities = 126/445 (28%), Positives = 195/445 (43%), Gaps = 28/445 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+ VIGGG GG+ G V ++ Q GG C+N GC+P K M +
Sbjct: 4 FDVVVIGGGPGGMTAGMMLKQAGKSVAII-------QENHDSFGGVCLNRGCMPTKSMLK 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA + + YG ++ S++ + + L + + + + L + +I G
Sbjct: 57 AAKVYRDAQNSEKYGLDL-SVNPVDLT--RLRAVADADLNMLRHMVQGKLTDARIAVFRG 113
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGHP 198
G F H L +GS ++I + I+IA G P P P +SSD I
Sbjct: 114 KGSFLSEHELQICQADGSSEQIRGEKIIIATGSVPAELPCAPFDGHSILSSDQILKNTDL 173
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P K L++G G IG E A N+ G T++ L D++ + + S EQ+G+
Sbjct: 174 PHKLLIIGGGAIGCEFATLYNTFGSRVTLVEAMDSLLPREDKEAGKTLQSTFEQQGITVK 233
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
S+ +E G + + + E FD VL+ GR A LNL+AAGV
Sbjct: 234 TGAAIKSI-SVEAGTVHVHYDGSCATEE----FDKVLVGIGRTANIAGLNLDAAGVATEQ 288
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
+ K + E QT V +IYA+GDV+ G L A G LLA+ + G P+D+ V
Sbjct: 289 GAVK-VNEMMQTTVPHIYALGDVIGGM-TLAHAAEKEGYLLAQNLIQGTRHPLDHRAVPR 346
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
VF E VG E AR G ++ + P + + + ++K + + E
Sbjct: 347 VVFCHPEVAAVGTHE----ARAG---IKAFTMPQAPNGRAVVDK-VAPAFVK-LFIEEDT 397
Query: 438 QRILGLHFVGPVAGEVIQGFAAAVK 462
+I G +G A E+I A AV+
Sbjct: 398 SQIAGAIIIGEGATEMIHEMAVAVE 422
>UniRef50_Q67B06 Cluster: Dihydrolipoyl dehydrogenase; n=22;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Bartonella
henselae (Rochalimaea henselae)
Length = 468
Score = 146 bits (353), Expect = 1e-33
Identities = 133/451 (29%), Positives = 208/451 (46%), Gaps = 29/451 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
YD+ VIG G GG A +A LG K +++ + LGGTC+NVGCIP K L+H
Sbjct: 3 YDVVVIGAGPGGYVAAIKAAQLGLKTAIIE--------KRMTLGGTCLNVGCIPSKALLH 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ + E+ H G S+ K+N + + + + +++ KID
Sbjct: 55 ASEVFAETQHGFETLG---ISIAKSKLNLEQMMAHKKAVVTANTSGVSFLMKKNKIDTFF 111
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VE----YCISSDDIF 193
G + +A + ++G+K+ I KNI+IA G IPG VE +SS
Sbjct: 112 GTAKILNAGQIEVVARDGNKQTIETKNIIIATGSES--SGIPGVNVEIDEKVIVSSTGAL 169
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQK 252
+L P + +VVGAG IG E + LG T++ + L D ++++ ME++
Sbjct: 170 ALEKVPTRMIVVGAGVIGSELGSVWSRLGAKVTIIEYLNKVLGSMDGEVSRQFQKIMEKQ 229
Query: 253 GVVFH-NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
G+ F V + Q+ E E D VL+ATGR+ T+ L LE A
Sbjct: 230 GIEFKIGAKVTAITQSGSVAQVTFEAVKGGPSETLE--ADVVLIATGRFPYTEGLGLEEA 287
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
GV I QTN+ +YA+GDV++G P L A G +A + AG ++
Sbjct: 288 GVQLDERGFITIDAHWQTNIPGVYAIGDVVKG-PMLAHKAEEEGVAVA-EILAGQKGHVN 345
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAV 431
+D + + V+T E VG +EE L G D F Q++ + ++K +
Sbjct: 346 FDVIPSVVYTQPEIASVGKTEE-ELKAAGIDYNVGKFPFMANGRARAMQKS--DGFVKIL 402
Query: 432 ALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
A ++ R+LG H +G AGE+I A ++
Sbjct: 403 ADKKT-DRVLGGHILGFGAGEMIHEIAVLME 432
>UniRef50_Q1GQ53 Cluster: Mercuric reductase MerA; n=91;
Bacteria|Rep: Mercuric reductase MerA - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 479
Score = 145 bits (352), Expect = 2e-33
Identities = 123/446 (27%), Positives = 192/446 (43%), Gaps = 26/446 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL V+GGGS G + A A GA+V V+ GT +GGTCVNVGC+P K + +
Sbjct: 16 YDLIVVGGGSAGFSAAITAAEQGAQVAVIG------AGT---IGGTCVNVGCVPSKALIR 66
Query: 80 AALLGESIHEAVAYGWEVPSLDA--IKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
A ESIH A A ++A +W + + + + DL +
Sbjct: 67 AV---ESIHHANAAPMRFNGVEAGARMADWGKVIAEKDSLVSGLRQAKYADL----LPLY 119
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLG 196
N + + L+ + TA IVIA G RP P IPG + + S L
Sbjct: 120 NNIAYHEGTARLVENGVEAGGRRFTADRIVIATGTRPAVPAIPGLPDVDALDSTTALDLT 179
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P +V+G GYIG+E A + G T++ RS L + ++ A+T + +G+
Sbjct: 180 ELPKSMIVLGGGYIGVELAQMFSRAGVDVTLVFRSRLLPDMEPEIGAALTDYLSSEGITV 239
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
S K G E V + +L+ATGR + L L AGV
Sbjct: 240 LGDLAYQSAHKTAEGGTALTVLRNGVAE--TIVAERLLVATGRAPNVEDLGLIEAGVKQT 297
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ I+ + +T+V +YA GDV G+ + +A + ++ A+ G + D +
Sbjct: 298 LSGAIIVDDHMRTSVRGVYAAGDV-TGRDQFVYMAAYGAKIAAKNALNGDSLRYDNSAMP 356
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
VF+ + VG +E A+A A + P + R+ R +K VA
Sbjct: 357 AVVFSDPQVASVGFTEAQAIAAGYATRTSTLPLENVPRA--LAARDTRG-LIKLVA-DGR 412
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
+++LG H + P + IQ A A++
Sbjct: 413 TRKLLGAHILAPEGADSIQTAAMAIR 438
>UniRef50_Q8F6S8 Cluster: Dihydrolipoyl dehydrogenase; n=30;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Leptospira
interrogans
Length = 467
Score = 145 bits (351), Expect = 2e-33
Identities = 124/450 (27%), Positives = 209/450 (46%), Gaps = 28/450 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LM 77
++D+ VIG G GG CA LG K +++ + LGGTC+NVGCIP K L+
Sbjct: 4 EFDVVVIGAGPGGYVCAIRCAQLGFKTAIIE--------KRKTLGGTCLNVGCIPSKALL 55
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
+ +++H+ +G V +D + +N L +K V + + KI
Sbjct: 56 DSSEEYHKTLHKLEVHGISVGKVD-LDLN--KLMNRKDQIVKEVTDGVDFLMNKNKIKRY 112
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAV---EYCISSDDIFS 194
G G+ A + +G K+ ++AK+IV+A G P DIPG + I+SD
Sbjct: 113 EGFGKVLSAGKVEVAFNDGKKETLSAKHIVVATGSVPI--DIPGLTVDGKNIITSDHAID 170
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQK 252
+ P K +++GAG IGLE LG TV V +P + D+QM + + +
Sbjct: 171 VRKLPKKMIIIGAGVIGLELGSVWGRLGTSVTV-VEFLPGLISNVDRQMGSLLERSLTSQ 229
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
G+ F + + G +K + ++++ + + + D VL+A GR + + LE AG
Sbjct: 230 GMEFLFEHKVKGAATTKNG-VKVQIEDSKGESKDLEA-DVVLVAVGRRPFLEGVGLEEAG 287
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
V + +T+V IYA+GD ++G P L A G LA + AG + ++Y
Sbjct: 288 VAFTQRKRIQVDAHFKTSVPGIYAIGDAIDG-PMLAHKAEEEGVALA-ELLAGQSGHVNY 345
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
+ V ++T E VG EE A + +V + ++P N +K +A
Sbjct: 346 NAVPYVIYTWPEMAWVGKGEEELKA--AGIEYKVGKSLFRPNA-RSKAMNEAEGQVKILA 402
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
++ ++LG GP A +++ A A++
Sbjct: 403 DKKT-DKLLGAFVFGPRASDMVAELAVAME 431
>UniRef50_Q5ZV78 Cluster: Mercuric reductase; n=5; Legionella
pneumophila|Rep: Mercuric reductase - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 714
Score = 144 bits (350), Expect = 3e-33
Identities = 133/447 (29%), Positives = 208/447 (46%), Gaps = 35/447 (7%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
DLA+IGGG+GGL+ A LG KV +++ +GG C+N GCIP K + A
Sbjct: 248 DLAIIGGGAGGLSLASGCSQLGLKVVLVE---------SGKMGGDCLNYGCIPSKSLLAA 298
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREK-KIDYVNG 139
A A +G +AIKIN+ + + V I +++ V E + +
Sbjct: 299 AKTFYYAKHATHFGVHT---EAIKINFQQVMQHVHQIIDNISEHDSVQRFESLGVQVIKQ 355
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIFSLGH 197
+G+F + TL A I AK V+A G P P IPG AV Y +++ IF L
Sbjct: 356 VGKFLNPDTLQA-----GDSIIKAKRFVVATGSSPFIPPIPGLDAVSY-FTNETIFDLKE 409
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P +V+G G IG E A LG T+L L D + ++M+ +V H
Sbjct: 410 QPEHLIVIGGGPIGCELAQAFAMLGSKVTLLEGLNLLPKDDPDCVAVLRTQMKSMSIVIH 469
Query: 258 NKCVPLSVEK-LETG-QLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
+ + +TG + +QNT+ +L+ATGR A K L+LE AGV
Sbjct: 470 EQIEITQINSHPDTGISVCFEFQNTQFTITASH----LLIATGRRANVKPLDLEKAGVK- 524
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
+++ G + + QT+ IYA+GDV G + T +A + ++ R + +DY +
Sbjct: 525 LTSKGVEVNKYLQTSNKKIYALGDV-TGLYQFTHMASYQASIVLRNIVFKLPSKVDYRAI 583
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
+T E VG+ AL A +E + + +R++ N +K + ++
Sbjct: 584 PWVTYTDPELAHVGIGVSDALKHPDAQIIEWP---FVDNDRAQTERSL-NGKIKIITDKK 639
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
A RILG+ VGP AGE+I + A++
Sbjct: 640 A--RILGVTIVGPHAGELILPWVMAIR 664
>UniRef50_Q5UWH2 Cluster: Dihydrolipoyl dehydrogenase 3; n=6;
Halobacteriaceae|Rep: Dihydrolipoyl dehydrogenase 3 -
Haloarcula marismortui (Halobacterium marismortui)
Length = 477
Score = 144 bits (350), Expect = 3e-33
Identities = 134/459 (29%), Positives = 203/459 (44%), Gaps = 39/459 (8%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK- 75
T D+ VIG G GG A A L VT+++ K GG C+N GCIP K
Sbjct: 7 TTSTDVLVIGAGPGGYVAAIRAAQLALDVTLVE---------KGEYGGACLNRGCIPSKA 57
Query: 76 LMHQAALLGES--IHEAVAYGWEVPSLDAIKINWP-ALTEAVQNHIKSVNWVTRVDLREK 132
L+H + L E+ E Y +LD + INW + + + + I+ + V+L
Sbjct: 58 LIHGSKLASEAGQAEELGIYADPTVALDEM-INWKDGVVDQLTSGIEQLCTAAGVNL--- 113
Query: 133 KIDYVNGLGEFKDAHT--LIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISS 189
+ G EF D + +I + + + +N +IA G RP P E +SS
Sbjct: 114 ----LKGTAEFADENKVRIIHQGEGQGSESLKFENCIIATGSRPIEIPGFGFEDERIVSS 169
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSE 248
D + P + ++VGAGYIG+E A + LG +V+ + L +++ +A V
Sbjct: 170 DGALNFDTVPDELVIVGAGYIGMELATVYSRLGSDVSVIEMLEQALPSYEEDIASIVRKR 229
Query: 249 MEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGED-----VFDTVLMATGRYALT 303
E+ GV FH + + KA E D D +L+A GR +T
Sbjct: 230 AERLGVDFH---FGYTADSWAASDGKAVLTAVPADEAAHDSDIELTADRILVAVGRRPVT 286
Query: 304 KTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMF 363
TL+++ AGV + T +TN +I+AVGDV G+P L G +A +
Sbjct: 287 DTLSIDDAGVETNAQGFIPTDSTCRTNKEHIFAVGDV-AGEPMLAHKGSKEGE-VAAEVI 344
Query: 364 AGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNI 423
AG +DY + VFT E G VGL+E A A G V F R
Sbjct: 345 AGEPAAVDYQALPAAVFTDPEIGTVGLTENEA-ANKGMTPVTGEFQFQASGRALTANR-- 401
Query: 424 RNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+++ +A +E +R++G VGP A E+I AA ++
Sbjct: 402 AEGFVRIIATKET-ERVIGAQIVGPEASELIAEIAAMIE 439
>UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide dehydrogenase E3 component;
n=2; Proteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex dihydrolipoamide dehydrogenase E3
component - Thiobacillus denitrificans (strain ATCC
25259)
Length = 998
Score = 144 bits (348), Expect = 6e-33
Identities = 136/439 (30%), Positives = 201/439 (45%), Gaps = 30/439 (6%)
Query: 16 GTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK 75
G +D + V+GGG GG CA++ + G KV +++ P P GG C+ GCIP K
Sbjct: 527 GNWDVQVVVVGGGPGGEDCARDLADHGVKVMMVNN-EPFP-------GGECLWRGCIPSK 578
Query: 76 LMHQAA-LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDL-REKK 133
AA + H+A V K+NW A E + +++ + + K
Sbjct: 579 AWRAAADNIRNRAHDAEM---GVDGTANPKLNW-AQVEKHRRWVQTSRGEMALKADKGMK 634
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-----CIS 188
ID G GEF DAHTL T G ++ VIA G P IPGA E ++
Sbjct: 635 IDVREGYGEFVDAHTLKITPPEGEAYTVSFGAAVIATGAPAFVPPIPGARENLATGGVVT 694
Query: 189 SDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTS 247
SD I++L +PP K +VG G IG+E A G +L R L ++++ + + +
Sbjct: 695 SDTIWNLANPPKKLGIVGGGVIGVEMAQIFRDFGTEVLMLERHDRILAEIEEEIGKVLIA 754
Query: 248 EMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLN 307
+E++ V + + K G++ R+ + E E D D VLMATG+ T LN
Sbjct: 755 SLEKEITVVTSADIREVGGK--PGKMTLRYADKEGAESTFDC-DVVLMATGKRPDTSRLN 811
Query: 308 LEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT 367
L+ GV + K+ A T+ NIYAVGDV+ G L A GR+ A + A+
Sbjct: 812 LDKVGVALDGAAIKVDARC-CTSTPNIYAVGDVIGGY-MLAHTAATQGRVAASNLLGHAS 869
Query: 368 QPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCY 427
+ D D F+ + G VGLS A A+ G D VE + I
Sbjct: 870 E-YDQDRDCGVTFSRPQAGFVGLSVAQAKAK-GIDAVEAKMPMSIDAKAMITGET--EGM 925
Query: 428 LKAVALREAPQRILGLHFV 446
+K VA + RI+G+H++
Sbjct: 926 IKLVA-DKTTGRIIGVHYL 943
>UniRef50_A4J8D3 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Desulfotomaculum reducens MI-1|Rep: Dihydrolipoyl
dehydrogenase - Desulfotomaculum reducens MI-1
Length = 463
Score = 144 bits (348), Expect = 6e-33
Identities = 133/448 (29%), Positives = 210/448 (46%), Gaps = 31/448 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+ VIGGG GG A A LG +V +++ K LGGTC+N GCIP K + +
Sbjct: 6 FDVVVIGGGPGGYTAAARAAALGGRVALVE---------KEALGGTCLNQGCIPTKTLLK 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+ + E++ +A +G EV ++ L Q IK +N ++ KI G
Sbjct: 57 STEVLETVKKAKDFGVEV---GVPEVALEKLINRKQAVIKRLNTGVEFLMKSGKISVFQG 113
Query: 140 LGEFKDAHTLIATLKNGSKKEI-TAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLGH 197
G+ A+ + T+ N SK+ I + I+IA G RP P + E I+S+ L
Sbjct: 114 EGKITGANEI--TVSNPSKQVILRTQKIIIATGSRPAVIPGLETDGEKIINSNHALMLSD 171
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKGVVF 256
PG L++G G IG+E A + LG T++ + F D++++ + M ++ +
Sbjct: 172 VPGSLLIIGGGAIGVEFASIYHKLGAKVTLVEAMDRILPFADEEVSNGLKQLMTREKISI 231
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVTC 315
V E G L N +T + ++ D VL+A GR + L LE G+
Sbjct: 232 LTSAKVSGVNNSEEGLL----VNVDTPKGIQEFRVDKVLVAVGRRPNVENLGLEEIGIQI 287
Query: 316 VSNSGKIIAET-EQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
G+I+ T +TNV NIYAVGD G L VA G ++A G + MDY
Sbjct: 288 --ERGRIVVNTYMETNVPNIYAVGDA-TGGILLAHVASTEG-IVAAANAMGGHKEMDYAV 343
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V + ++T E VG++E A A+ +V V + + + + + +K +A
Sbjct: 344 VPSCIYTSPELASVGITE--AQAKEQGIQVVVGKSQFTGSGKALAMGENKG-LVKIIADV 400
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
E +ILG+H +GP A +I A+K
Sbjct: 401 E-NGKILGVHILGPQATSLISEATLAIK 427
>UniRef50_P14218 Cluster: Dihydrolipoyl dehydrogenase; n=65;
cellular organisms|Rep: Dihydrolipoyl dehydrogenase -
Pseudomonas fluorescens
Length = 478
Score = 143 bits (347), Expect = 8e-33
Identities = 125/442 (28%), Positives = 204/442 (46%), Gaps = 23/442 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLD-YVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+D+ VIG G GG A A LG K ++ Y+ +G K LGGTC+NVGCIP K +
Sbjct: 5 FDVVVIGAGPGGYVAAIRAAQLGLKTACIEKYI--GKEG-KVALGGTCLNVGCIPSKALL 61
Query: 79 QAALLGESIHEAVAYGWEVPSLDA--IKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
++ HEA ++V ++A + I+ PA+ N +K++ + +
Sbjct: 62 DSSY---KYHEAKE-AFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTS 117
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSL 195
G G+ + T +G + + A+N++IA G RP P P + + + S
Sbjct: 118 FEGHGKLLANKQVEVTGLDGKTQVLEAENVIIASGSRPVEIPPAPLSDDIIVDSTGALEF 177
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGV 254
P K V+GAG IGLE LG TVL L D+Q+A+ + ++G+
Sbjct: 178 QAVPKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGL 237
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
N + V E + + T+ ++ FD +++A GR +T L +GVT
Sbjct: 238 ---NIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVT 294
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ + +T+V ++A+GDV+ G L A G ++A R+ AG M+YD
Sbjct: 295 LDERGFIYVDDHCKTSVPGVFAIGDVVRG-AMLAHKASEEGVMVAERI-AGHKAQMNYDL 352
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEV-YHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ + ++T E VG +E+T A+ VEV F N +K +A
Sbjct: 353 IPSVIYTHPEIAWVGKTEQTL----KAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIAD 408
Query: 434 REAPQRILGLHFVGPVAGEVIQ 455
+ R+LG+H +GP A E++Q
Sbjct: 409 AKT-DRVLGVHVIGPSAAELVQ 429
>UniRef50_Q8R9D9 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Thermoanaerobacter|Rep: Dihydrolipoyl dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 451
Score = 143 bits (346), Expect = 1e-32
Identities = 131/448 (29%), Positives = 213/448 (47%), Gaps = 39/448 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ V+GGG GG A LG KV +++ + LGGTC+N GCIP K+
Sbjct: 2 NYDVIVVGGGPGGYTAAIRLSELGKKVALIE---------EDSLGGTCLNRGCIPTKVYA 52
Query: 79 QAALLGESIHEAVAYGWEVP-SLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
AA L I EA +G +LD K+ V+ + V ++ + ID +
Sbjct: 53 HAAELVTRIKEAKDFGITAEYTLDIAKLR-QKKERVVKRLVGGVGYLMNL----HHIDVI 107
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSDDIFSLG 196
NG G F D +T+ NG+K TA+N +IA G + P I G +E ++SD L
Sbjct: 108 NGKGTFIDKNTVEV---NGAK--YTAENFIIATGSKVFLPPIEGIDLEGVMTSDKALELE 162
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKGV 254
P K +++GAG IGLE A SLG +++ +P L D+ + + ++++ +
Sbjct: 163 KIPEKIVIIGAGIIGLEFANIYASLG-SKVIMIEMLPQLLPMLDRDVVGVMEKALKKQKI 221
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
H + VEK+E G L+ + QE E D VL+A GR + ++A +
Sbjct: 222 ELH---LNSKVEKIERG-LRVIYTENGNQESVE--CDAVLVAVGR--VPNVNGVDALNLE 273
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
++ G + +T++ NIYA+GDV G +L VA + G ++A AG + D
Sbjct: 274 -MNGRGIKVDSHMRTSIENIYAIGDV-TGGIQLAHVASYQG-IVAAHNIAGEEKEADLTA 330
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V ++T E VGL+E A ++G K+ + + + + ++K +A
Sbjct: 331 VPNCLYTNPEVAWVGLNESQAREKYGEVKIGTFPYTALGRAMTMGE---SDGFVKIIA-E 386
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
R++G+ +G A E+I A+K
Sbjct: 387 GKYGRVVGMEIIGAGATEIIHEGVLAIK 414
>UniRef50_A6TMP2 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Alkaliphilus metalliredigens QYMF|Rep: Dihydrolipoyl
dehydrogenase - Alkaliphilus metalliredigens QYMF
Length = 457
Score = 143 bits (346), Expect = 1e-32
Identities = 109/382 (28%), Positives = 190/382 (49%), Gaps = 32/382 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ V+GGG GG A +A +LG KV +++ GG C+N GCIP K + +
Sbjct: 3 YDVLVLGGGPGGYVAAIKAAHLGGKVALVE---------NGYFGGVCLNWGCIPTKALLK 53
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + + + YG E + INWPA+ + ++ + + L++ K+D +G
Sbjct: 54 NARVYQDVLMGDFYGIEGIDKSQLSINWPAMLKRKDRIVRQLVGGVKGLLKKNKVDVFDG 113
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG-----AVEYCISSDDIFS 194
G DA+ + +K +++ K ++IA G P PDIPG ++S ++ S
Sbjct: 114 FGTLIDANHI--EVKG---QQLEGKKLIIATGTSPMIPDIPGLEASMKAGNILTSKELLS 168
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKG 253
+ P +++G G I +E A LN+L TV+ RS L+G +++MA ++ ++ ++
Sbjct: 169 IEALPKSVVILGGGVIAIEFATLLNALDVEVTVIQRSDRILKGVEEEMALTLSKDLIKRK 228
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
V SVEK+E ++ + E G D +L++ G K LEA +
Sbjct: 229 VKIVTNS---SVEKIEGTRVFTKINGEEEIFEG----DKILLSLGTSPNVK--GLEALSL 279
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ G I + +T+++ +YA+GDV GK +L VA G ++A G + ++Y+
Sbjct: 280 D-MDKKGIITNDKMETSITGVYAIGDV-NGKYQLAHVASAEG-IVAAENAMGGNEELNYN 336
Query: 374 NVATTVFTPLEYGCVGLSEETA 395
V + +++ E VGL+EE A
Sbjct: 337 IVPSCIYSFPEIASVGLTEEEA 358
>UniRef50_Q8TIX6 Cluster: Glutathione reductase; n=6;
Methanosarcina|Rep: Glutathione reductase -
Methanosarcina acetivorans
Length = 450
Score = 143 bits (346), Expect = 1e-32
Identities = 121/446 (27%), Positives = 192/446 (43%), Gaps = 27/446 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ ++G G+ G A A + G K ++D GGTC GC PKK++
Sbjct: 4 EYDIIILGTGTAGRTLAGRAKSSGLKFAIID---------SREYGGTCPLRGCDPKKVLA 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A+ + + + G + ++INW +L E + + T + ID +
Sbjct: 55 GASEATDWNNRLIGKG--AGTEKPLEINWSSLIEFKRTFTRDYPRETEKMFADMGIDMYH 112
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
G F++ +T++ K ++ K I +A G +P +IPG EY I+S++
Sbjct: 113 GRANFENENTILV-----GKDKLKGKYIFLATGSKPRKLNIPGE-EYLITSEEFMETEKF 166
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFH 257
P K + VG GY+ E A G +L RS PLR FD +MA + E G+
Sbjct: 167 PEKIIFVGGGYVSFEFAHIALRAGAEVLILHRSEKPLRDFDSEMADLLVRASEAAGMRIL 226
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVTCV 316
++VE+ L TET + D V+ GR + L LE AG+T
Sbjct: 227 TDRPVVAVEREGDRFLVRAEYKTETGSETQTFNADMVVNGAGRTPDIEDLRLENAGITA- 285
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
G I+ + QT+ +YA GD +LTPVA G + A +F +DY +
Sbjct: 286 EKKGIIVDKHMQTSNPRVYAGGDCTAEGMQLTPVATLQGEIAAANIFDENRAEIDYTGIP 345
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+ VFT VG++E +H F +++ +R + + E
Sbjct: 346 SAVFTIPVLASVGITEAKVNDKHRV-------IFRDRSKWSTTRRAGLEFAASKIIVDET 398
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
I+G H +GP A E I FA A++
Sbjct: 399 NDHIVGAHILGPNAEEAINIFATAMQ 424
>UniRef50_Q6MPR7 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Deltaproteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Bdellovibrio bacteriovorus
Length = 473
Score = 142 bits (344), Expect = 2e-32
Identities = 133/453 (29%), Positives = 205/453 (45%), Gaps = 34/453 (7%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
++D+ VIG G GG A + LG K V++ + LGG C+NVGCIP K M
Sbjct: 3 NFDVVVIGAGPGGYVAAIRSAQLGFKTAVIE---------REFLGGVCLNVGCIPSKAMI 53
Query: 79 QAA-LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
A LL ++ H G + I ++ L + Q+ ++ L+ + +
Sbjct: 54 TATHLLHKAQHNFKEMGLNIKG--GIDVDMKQLVKWKQSVSDKMSGGVNQLLKGYGVTII 111
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG----AVEYCISSDDIF 193
G EFK + I+ + + + AK V+A G RP +IPG + C SS
Sbjct: 112 KGDAEFKSSKE-ISVKSSAGTESVQAKYFVVATGSRPI--EIPGFKFDEKDIC-SSTGAL 167
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGF-DQQMAQAVTSEMEQ 251
+ P + V+G GYIGLE + +L LG TV+ +S L G D AQ VT ++ +
Sbjct: 168 AFDTIPKRVAVIGGGYIGLEISSYLRKLGTEVTVIEAQSALLAGVVDPDCAQIVTRKLTK 227
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEA 310
GV +K++ G E + E V D +L+ GR NL+A
Sbjct: 228 AGVNVLYGAKAKGQKKVKDGYEVT----VEINGKDEVVKCDKILVTVGRRPNGDQANLKA 283
Query: 311 AGVTCVSNSGKIIAETEQ-TNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
AG+ V G + + ++ TNVSNI+A+GD+ G+P L A H G L+A + AG +
Sbjct: 284 AGIQ-VDERGFVKVDAQRRTNVSNIFAIGDI-AGQPMLAHKASHEGVLVA-EVIAGHNRV 340
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
D V VFT E G++E A A+ D + F + ++K
Sbjct: 341 YDAKTVPAVVFTDPEIAAAGMTEAEAKAKGHTDLLISKFPFAANGRAVSMMET--DGFVK 398
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+A ++ +LG+H VGP A +I A++
Sbjct: 399 MIADKKT-HVLLGVHIVGPEASNLISEAVLAIE 430
>UniRef50_Q9D8I4 Cluster: Adult male small intestine cDNA, RIKEN
full-length enriched library, clone:2010001F03
product:ADULT MALE SMALL INTESTINE CDNA, RIKEN FULL-
LENGTH ENRICHED LIBRARY, CLONE:2010001F03, FULL INSERT
SEQUENCE, full insert sequence; n=8; Eukaryota|Rep:
Adult male small intestine cDNA, RIKEN full-length
enriched library, clone:2010001F03 product:ADULT MALE
SMALL INTESTINE CDNA, RIKEN FULL- LENGTH ENRICHED
LIBRARY, CLONE:2010001F03, FULL INSERT SEQUENCE, full
insert sequence - Mus musculus (Mouse)
Length = 101
Score = 140 bits (340), Expect = 5e-32
Identities = 65/88 (73%), Positives = 70/88 (79%), Gaps = 2/88 (2%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL VIGGGSGGLACAKEA LG KV V DYV PSP+GTKWGLGGTCVNVGCIPKKLMHQ
Sbjct: 16 FDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQ 75
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINW 107
AALLG I +A YGWEV ++ NW
Sbjct: 76 AALLGGMIRDAHHYGWEV--AQPVQHNW 101
>UniRef50_Q7NDN4 Cluster: Gll4201 protein; n=1; Gloeobacter
violaceus|Rep: Gll4201 protein - Gloeobacter violaceus
Length = 450
Score = 140 bits (340), Expect = 5e-32
Identities = 135/447 (30%), Positives = 196/447 (43%), Gaps = 34/447 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL V+G G G + AK G KV V+D P GGTC GC PKK++ Q
Sbjct: 5 YDLVVLGTGVAGSSVAKRCREAGWKVAVVD---SRP------FGGTCALRGCTPKKVLVQ 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A L + G + +I+WP L ++ I+ + + E I+ +G
Sbjct: 56 AGELLDRWRHLAGKGLRA---EEARIDWPELMRFKRSLIEPLPAAREAEYAEAGIESYHG 112
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
+ F A L G+ + + ++IA G RP I G E+ SSDD LG P
Sbjct: 113 VARFVGATALEV---EGA--HLQGEKVLIATGSRPATLGIEGE-EHLASSDDFLELGTLP 166
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFHN 258
+ + VG GYI +E A G VL + PL FD + + + G +
Sbjct: 167 RRIVFVGGGYISMEFAHLAARAGSQVHVLHQDERPLAPFDPDLVDRLIEATRELGALCLC 226
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
V ++EK G L +T+ + G D V+ R + L+L+ AGV
Sbjct: 227 HKVK-AIEKTAQGLLV----HTDG-DGGPYAADLVVHGASRVPNVEALDLDGAGVEAGKK 280
Query: 319 SGKIIAETEQTNVSNIYAVGDVLEGK-PELTPVA-IHAGRLLARRMFAGATQPMDYDNVA 376
K+ A + + +YA GDV + P+LTPVA +HA +A + G T+ ++ A
Sbjct: 281 GIKVNAHLQSVSNPAVYAAGDVADAPGPQLTPVAGLHA-ETVAENLLKGNTRSLEQAVFA 339
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+TVFT VGL EE A A+ G Y + R++ Y L E
Sbjct: 340 STVFTVPALAGVGLLEEQAQAQ-GLH----YRVLQADHRDRLAVRSLAAPYAAHKILVEE 394
Query: 437 P-QRILGLHFVGPVAGEVIQGFAAAVK 462
P RILG H +GP A E+I FA A++
Sbjct: 395 PGGRILGAHLLGPFATEIINVFALAIQ 421
>UniRef50_Q1AT12 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 471
Score = 140 bits (340), Expect = 5e-32
Identities = 123/445 (27%), Positives = 203/445 (45%), Gaps = 32/445 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL +IGGG+ G A A LG V +++ +G LGGTC+N+GCIP K + Q
Sbjct: 5 FDLVIIGGGNAGYIPAIRASQLGMSVALVE----RREGGH--LGGTCLNLGCIPTKALLQ 58
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + +G +V ++ ++ + + + +++ K+ NG
Sbjct: 59 TAAMLHDARNGEEFGVKVGD---VRFDYRQAAKRRDQVVNQLRRGVAGLMKKNKVSVYNG 115
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLGHP 198
G F + L +G +E+ A+N++IA G + P + E ISSDD+ +
Sbjct: 116 TGSFIQPRRIKVELNDGGTEELEAENVLIATGSAVNTLPGLEFDGEKVISSDDVVTENDG 175
Query: 199 -PGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEMEQKGV 254
P +++G+G +G+E A N G T+ L R VPL D +++ + + E +G+
Sbjct: 176 YPESVIILGSGAVGVEFASMYNDFGTEVTIVEILDRLVPLE--DPEVSAELEKQFEGRGI 233
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQ---ERGEDVFDT--VLMATGRYALTKTLNLE 309
+C L+ K + G L + + E GE+ + +L+A GR +T+ LNLE
Sbjct: 234 ----RC--LTGTKADPGSLDKSGDGVKIKVAGEGGEETLEAEKLLVAVGRKTVTEELNLE 287
Query: 310 AAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
A V + E +T+ +YA GDV+ G L A H G + M P
Sbjct: 288 ATSVKTDDRGIIQVDEFYRTDEPGVYAAGDVIGGY-WLAHAAGHEGIVAVEHMAGKDPMP 346
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
+D + + F E GLSEE AR +++V ++ + + N +LK
Sbjct: 347 LDQNLIPRVTFCRPEIASFGLSEEQ--AREEGYEIKVGKFPFRAIGKALIEGE-PNGFLK 403
Query: 430 AVALREAPQRILGLHFVGPVAGEVI 454
VA E ILG+H +GP E+I
Sbjct: 404 VVADAET-DLILGMHAIGPHVTELI 427
>UniRef50_A4BJ37 Cluster: Mercuric reductase; n=2; unclassified
Gammaproteobacteria|Rep: Mercuric reductase - Reinekea
sp. MED297
Length = 471
Score = 140 bits (340), Expect = 5e-32
Identities = 129/440 (29%), Positives = 210/440 (47%), Gaps = 41/440 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
YDL VIG G+ GL A A+ G KV +++ P GG C GC+P K L++
Sbjct: 4 YDLIVIGSGAAGLTAAFTALGFGKKVLIIEKDRP---------GGECTWSGCVPSKGLIN 54
Query: 79 QAALLGESIHEAVAYG-WEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
+A + +H A + +++ + ++ ++EA+ H T L + +V
Sbjct: 55 RA----KDVHTARKFADFDIDTRTLLQ-EVRGVSEAIYEH------ETPEVLEKAGAVFV 103
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLG 196
G F DA TLK G ++ K I+IA G P P IPG E ++++ F
Sbjct: 104 QGEAAFVDA----KTLKVG-QETYRGKRIIIATGSSPLVPPIPGLDEVPFLTNESFFEQE 158
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQA--VTSEMEQKGV 254
P +V+GAG IG+E + +N LG TV V +P F ++ A A + + ++GV
Sbjct: 159 TLPKSIIVLGAGAIGMELSQAMNRLGVEVTV-VEMMPEIMFREEPAYAAILRERLVKEGV 217
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
F + VEK ETG R + E G+ T+L+A GR A +LNL+AAG+
Sbjct: 218 RFQLGTKAVGVEKTETG---IRLSTEKDGESGQIEAQTLLLALGRKANIGSLNLDAAGIK 274
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
++ G ++ QT +YA GDV G +L+ +A ++ A + +Y++
Sbjct: 275 --ADRGIVVDAHLQTTAKGVYACGDV-AGPYQLSHMANFQAKIAAMNAILPINRKANYEH 331
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
VA T FT E+ G++E A ++G D++ V+ Y + + + + + + L
Sbjct: 332 VAWTTFTDPEFARAGMTEAEAREQYG-DRIRVFE--YDMAD-KLDRAKTKAGDIGHIKLI 387
Query: 435 EAPQRILGLHFVGPVAGEVI 454
R+LG H + AGE+I
Sbjct: 388 TLKGRVLGAHILAERAGELI 407
>UniRef50_P30341 Cluster: Mercuric reductase (EC 1.16.1.1) (Hg(II)
reductase); n=27; Bacteria|Rep: Mercuric reductase (EC
1.16.1.1) (Hg(II) reductase) - Streptomyces lividans
Length = 474
Score = 140 bits (340), Expect = 5e-32
Identities = 130/448 (29%), Positives = 197/448 (43%), Gaps = 29/448 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDLA+IG G+G A A A N G V +++ +GT GGTCVNVGC+P K +
Sbjct: 8 YDLAIIGSGAGAFAAAIAARNKGRSVVMVE------RGTT---GGTCVNVGCVPSKALLA 58
Query: 80 AALLGESIHEAVAYGWEVPSLDAIK--INWPALTEAVQNHIKSVNWVTRVDLR-EKKIDY 136
AA E+ H A A P + A + +++PAL + + DL E
Sbjct: 59 AA---EARHGAQAAS-RFPGIQATEPALDFPALISGKDTLVGQLRAEKYTDLAAEYGWQI 114
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISSDDIFS 194
V+G F D L L +G + A + +IA G P P I G V+Y ++S
Sbjct: 115 VHGTATFADGPMLEVALNDGGTATVEAAHYLIATGSAPTAPHIDGLDQVDY-LTSTTAME 173
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGV 254
L P L++G GY+GLE A LG T+ VRS + +++ + + ++G+
Sbjct: 174 LQQLPEHLLILGGGYVGLEQAQLFARLGSRVTLAVRSRLASREEPEISAGIENIFREEGI 233
Query: 255 VFHNKCVPLSVEKLETGQLKA-RWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
H + +V + G L + + Q R +L+ATGR ++T L LE GV
Sbjct: 234 TVHTRTQLRAVRRDGEGILATLTGPDGDQQVRASH----LLIATGRRSVTNGLGLERVGV 289
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
++ E +T+ I+A GDV P+ VA G L+A GA + +DY
Sbjct: 290 KTGERGEVVVDEYLRTDNPRIWAAGDV-TCHPDFVYVAAAHGTLVADNALDGAERTLDYT 348
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ FT VGL+E A + P + R+ R +K +A
Sbjct: 349 ALPKVTFTSPAIASVGLTEAQLTEAGIAHQTRTLSLENVPRA--LVNRDTRG-LVKLIAE 405
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAV 461
R ++L H + AG+VI A+
Sbjct: 406 R-GTGKLLAAHVLAEGAGDVITAATYAI 432
>UniRef50_Q5V791 Cluster: Mercuric reductase; n=1; Haloarcula
marismortui|Rep: Mercuric reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 484
Score = 140 bits (339), Expect = 7e-32
Identities = 129/459 (28%), Positives = 191/459 (41%), Gaps = 34/459 (7%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK- 75
T DYDL ++GGG+ A EA +++ P +GGTCVNVGC+P K
Sbjct: 4 TSDYDLVILGGGAAAFAAITEASRRDLSTAMVNTGLP--------IGGTCVNVGCVPSKH 55
Query: 76 ---LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREK 132
+ A E+ +AV Y E P++D W A ++ VD+ E
Sbjct: 56 LLAVAESGAAASENPFDAVRYP-EEPTVD-----WAAALNDTDELVERFRQENYVDIAEH 109
Query: 133 -KIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISS 189
+ID G G+ D T+ IT + ++A G P P I G V+Y +S
Sbjct: 110 FEIDIYEGYGQLVDDTTIEVVDGADEGARITGEKALVATGSSPWAPPIDGLYDVDY-YTS 168
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSE 248
+ I P L++G GYI LE L+ +G TVL RS L + Q+ + +
Sbjct: 169 ETILEERDLPESILMLGGGYIALEWGQILHRVGIDVTVLQRSDRVLSDMEGQLGREMQRA 228
Query: 249 MEQKG--VVFHNKCVPLSVEKLETG-QLKARWQNTETQERGED---VFDTVLMATGRYAL 302
E++G V+ N + + G + ET G++ D + +ATG
Sbjct: 229 FEEEGIEVITGNDFQRVRTLAADGGAEAIQSGVAVETTIDGDERTVTGDALFVATGVQPN 288
Query: 303 TKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRM 362
++ + LE G+ + + E QT +IYA GDV+ G+PEL VA G +
Sbjct: 289 SEGIGLETVGIETNPDGTIRVDEYFQTTNPDIYAAGDVI-GEPELETVAAKEGNHAVKNA 347
Query: 363 FAGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRN 422
F +DYD V VFT E VG +E + HG P + +
Sbjct: 348 FGNEGVSIDYDAVPAVVFTSPEVAAVGTTELEYMDEHGTCSCRTVQMADVPRAKAVENTD 407
Query: 423 IRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
L V I+G+H VGP A ++I AV
Sbjct: 408 ----GLVQVVKHHETDEIVGVHMVGPRAADMIMEATLAV 442
>UniRef50_A3CSE1 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Methanoculleus
marisnigri JR1|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Methanoculleus
marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length = 456
Score = 139 bits (337), Expect = 1e-31
Identities = 132/449 (29%), Positives = 190/449 (42%), Gaps = 35/449 (7%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ VIG G+ G A G +V ++D GGTC GC+PKK++
Sbjct: 4 EYDVVVIGTGNAGSDIAWHCRKAGMQVAIVD---------SRDYGGTCALWGCVPKKVLA 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
AA + H+ + G AI I+WP L Q V R I +
Sbjct: 55 GAAEVVSRAHDQLGNGIR----GAIAIDWPELIAFEQTFTDPVPRQKEERFRGAGIHTYH 110
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
GL F + +T + IVIA G P ++PG + SSDD F L
Sbjct: 111 GLARFAGPDRVAV-----GDDTLTGRYIVIAAGAHPRPLNVPGE-DLMTSSDDFFYLEAL 164
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFH 257
P + + VG GYI E A + G T+L RS L+ FD + + + G+
Sbjct: 165 PERIVFVGGGYISFEFAHIAAAAGSAVTILQRSGRALKEFDPDIVDRLLLASGEAGIDVQ 224
Query: 258 NKCVPLSVEKLETGQLKAR-WQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
+SVEK L+ R ++ E + G D+ + GR + L+ AAG
Sbjct: 225 MNMPLVSVEK-NAADLRVRAGRDGEEKTFGADM---AVHGAGRVSAVGELD-PAAGNVET 279
Query: 317 SNSGKIIAETEQTNVSN--IYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
G I+ + +VSN +Y GD G P+LTPVA+ ++ + G + DY
Sbjct: 280 DRRG-IVVDEHLRSVSNPAVYVAGDANPGSPQLTPVAVMDAHIVVDNILGGNARVADYSV 338
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYL-KAVAL 433
V + VFT VGL+EE A +K Y A R+I + + +
Sbjct: 339 VPSAVFTNPPIASVGLTEEAA-----KEKGIPYVANAGDLSGRFTNRSIGQKHAGYKLLI 393
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
E +RILG H +GP EVI FA A+K
Sbjct: 394 DEDSRRILGAHLIGPHVEEVINIFALAIK 422
>UniRef50_Q892P7 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Clostridia|Rep: Dihydrolipoamide dehydrogenase -
Clostridium tetani
Length = 589
Score = 138 bits (335), Expect = 2e-31
Identities = 123/450 (27%), Positives = 214/450 (47%), Gaps = 38/450 (8%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+A++G G GG A +A LGAKV +++ K +GGTC+N GCIP K ++
Sbjct: 132 DVAILGAGPGGYVAAIQAAKLGAKVVIVE---------KDKVGGTCLNRGCIPTKAFVRS 182
Query: 81 ALLGESIHEAVAYG--WEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ + ++ + YG E PS+D K+ V + + ++ +++ I+ ++
Sbjct: 183 SEVYSNVKNSEKYGISLENPSIDIKKV-VARKDNIVDKLVGGIQYL----IQKHNIELIS 237
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSDDIFSLGH 197
G G+ D +T+ I AKNIVIA G + I G+ ++ I+S++ L
Sbjct: 238 GNGKLIDRNTI-----ETKDALIKAKNIVIASGSKASVLPIKGSNLKQVITSEEALDLKE 292
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P K ++G G IG+E A ++G +V+ L D+ + + +T ++KG+ F
Sbjct: 293 VPEKIAIIGGGVIGMEFAFIYANMGVEVSVIEYFDNILSMLDEDVIKEITDIGKEKGIKF 352
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVF---DTVLMATGRYALTKTLNLEAAGV 313
+ + + E ++ N +GE+ F D VLM+ GR + + +E G+
Sbjct: 353 YTSSKVEEILEDENEGCIVKFTN-----KGEEKFIFCDKVLMSVGRQPYMENMGVEELGI 407
Query: 314 TCVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
N I T+ +T+VSNIYA+GDV +L VA H G ++A + G +DY
Sbjct: 408 ELNQNKRGIKVNTKMETSVSNIYAIGDV-TNVIQLAHVASHQG-IVAVKNIMGKDIQIDY 465
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
V + +FT E VG+ E+ +A+ VEV + + R ++K +
Sbjct: 466 SAVPSVIFTEPEIAVVGVCEK--IAKENNLDVEVGKFPFSANGKALTLGEDRG-FIKVIK 522
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+A +++G +G A ++I AVK
Sbjct: 523 -EKATGKVVGASIIGAHASDLIAELTLAVK 551
>UniRef50_Q28MH1 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation protein; n=9;
Rhodobacteraceae|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation protein - Jannaschia sp.
(strain CCS1)
Length = 484
Score = 138 bits (334), Expect = 3e-31
Identities = 89/238 (37%), Positives = 124/238 (52%), Gaps = 19/238 (7%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+DYDL VIGGGSGG+ A+ A GA+V + + + LGGTCV GC+PKKLM
Sbjct: 4 FDYDLFVIGGGSGGVRAARVAAAGGARVALAE---------ESRLGGTCVIRGCVPKKLM 54
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
AA E EA AYGW+V + +WP + + + + V R L ++
Sbjct: 55 VFAASYREGFSEARAYGWDV---EDGAFHWPVFRGHLNSELDRLEGVYRKLLDGSGVEIF 111
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
+G AHT+ NG +K TAK+I++A GGRP PD+P A + SDD+F+L
Sbjct: 112 DGRAIVAGAHTVSV---NGQEK--TAKHILVATGGRPTRPDMPNA-HLGLVSDDLFNLDA 165
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGV 254
P L++G GYI E A + LG T R LRGFD + + M ++G+
Sbjct: 166 LPKSMLIIGGGYIACEFACIMAGLGVKVTQYYRGAQILRGFDDEARGLIAEMMREQGI 223
Score = 123 bits (297), Expect = 9e-27
Identities = 74/176 (42%), Positives = 99/176 (56%), Gaps = 6/176 (3%)
Query: 287 EDVFDTVLMATGRYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPE 346
EDVFD VL ATGR T + LE AGVT ++ E QT V +IYA+GDV +
Sbjct: 283 EDVFDQVLFATGRTPNTDGMGLEDAGVTVGRRGEVVVDEYSQTGVPSIYAIGDV-TNRVN 341
Query: 347 LTPVAIHAGRLLARRMFAGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEV 406
LTPVAI G +F G+ P+D+D + + VFT EYG VGL+EETA + +EV
Sbjct: 342 LTPVAIREGMAFVETVFNGSPTPVDHDLIPSAVFTTPEYGSVGLTEETA---RDQEPIEV 398
Query: 407 YHAFYKPTEFFIPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
Y ++P + + R +K + +E ++ILG H V P AGE+IQ AVK
Sbjct: 399 YCTSFRPMQTAFAGKPWR-VMMKLIVSQET-RKILGCHIVAPAAGEMIQLAGIAVK 452
>UniRef50_Q03HI1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide dehydrogenase (E3) component,
related enzyme; n=1; Pediococcus pentosaceus ATCC
25745|Rep: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide dehydrogenase (E3) component,
related enzyme - Pediococcus pentosaceus (strain ATCC
25745 / 183-1w)
Length = 444
Score = 138 bits (333), Expect = 4e-31
Identities = 117/418 (27%), Positives = 193/418 (46%), Gaps = 32/418 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ +IG G GGL A G +V V++ WG GTC N GC PKK++
Sbjct: 4 YDVVIIGAGPGGLGLAYPLKEAGLEVAVVEE-------NLWG--GTCPNRGCDPKKVLLA 54
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + + G + + +I+WPAL + + V+ +R L + +ID +G
Sbjct: 55 AIEAKKQNQYLLGNGIK----NETQIDWPALMQFEKTFTDPVSRSSRSGLTDAQIDVYDG 110
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
EF D HTL + IT++ VIA G RP E +S D + H P
Sbjct: 111 HAEFIDHHTL-----KIDQTTITSEKFVIATGQRPSRLTNIENQEMMQTSTDFLKMDHLP 165
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFHN 258
+ +VG GYI E A + G ++ + PL+ F + + +++ +GV H
Sbjct: 166 NELALVGGGYIAFELAMIASGAGAKVHIIHHNQRPLKAFPKAYVDDLVDQLKTQGVEVH- 224
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
L ++ R++ ++ Q + + D V + GR +LNLE GV
Sbjct: 225 ----LGIDLKRVEPKDERFELSDGQ-GFKQIVDQVFVTAGRKPNDDSLNLEKIGVQ-TDR 278
Query: 319 SGKIIAETEQTNVSNIYAVGDVL-EGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
G ++ E +T+V NIYA+GDV+ + P+LTPV+ R LA+++ +DY + T
Sbjct: 279 GGIVVNEYLETSVDNIYAMGDVVSKALPKLTPVSGFEARYLAKKLTNATQAAIDYPAIPT 338
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
V+ + VG+ E A+ ++ E+ A + TE+F R +++ + K + E
Sbjct: 339 VVYGMPKLAKVGV--ELDEAQQHPEQYEIKTA--EMTEWF-TYRRLQDPFAKISVIHE 391
>UniRef50_Q8DD46 Cluster: Soluble pyridine nucleotide
transhydrogenase (EC 1.6.1.1) (STH) (NAD(P)(+)
transhydrogenase [B-specific]); n=43; Bacteria|Rep:
Soluble pyridine nucleotide transhydrogenase (EC
1.6.1.1) (STH) (NAD(P)(+) transhydrogenase [B-specific])
- Vibrio vulnificus
Length = 466
Score = 138 bits (333), Expect = 4e-31
Identities = 129/447 (28%), Positives = 190/447 (42%), Gaps = 32/447 (7%)
Query: 14 LAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP 73
+A +D+ VIG G GG A G KV V++ + +GG C + G IP
Sbjct: 1 MAHANHFDVIVIGSGPGGEGAAMGLTKAGLKVAVVEKES--------SVGGGCTHWGTIP 52
Query: 74 KKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSV-NWVTRVD---L 129
K + A + + + P + A + H KSV + TR+
Sbjct: 53 SKALRHA------VSRIIEFNSN-PLFCKNNSSLHATFSTILGHAKSVIDKQTRLRQGFY 105
Query: 130 REKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCIS 188
+ + G F DAHT+ T +G+++ TA VIA G RP+ P D+ E
Sbjct: 106 DRNQCQLIFGTARFTDAHTISVTQNDGTEEVYTADKFVIATGSRPYQPADVDFNHERIYD 165
Query: 189 SDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTS 247
SD I SL H P ++ GAG IG E A LG ++ R L D +++ A++
Sbjct: 166 SDSILSLKHDPRHIIIYGAGVIGCEYASIFRGLGVKTDLINTRDRLLAFLDNEVSDALSY 225
Query: 248 EMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLN 307
GVV N +E E G + Q + D +L A GR T LN
Sbjct: 226 HFWNSGVVIRNDETYERIEGTEDGVI------VHLQSGKKMKADCLLYANGRTGNTDKLN 279
Query: 308 LEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT 367
L A G+ S + QT V ++YAVGDV+ G P L A GR +A+ + G
Sbjct: 280 LPAVGLQGDSRGQLKVDGNYQTEVEHVYAVGDVI-GYPSLASAAYDQGRFVAQAITKGKA 338
Query: 368 QPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCY 427
D++ T ++T E VG +E+ A +V +F I ++I +
Sbjct: 339 DGYLIDDIPTGIYTIPEISSVGKTEQELTAAKVPYEVG-RSSFKHLARAQIAGKDIGS-- 395
Query: 428 LKAVALREAPQRILGLHFVGPVAGEVI 454
LK + RE + ILG+H G A E+I
Sbjct: 396 LKILFHRET-KEILGIHCFGERAAEII 421
>UniRef50_UPI000038D9FE Cluster: COG1249: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide dehydrogenase
(E3) component, and related enzymes; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1249:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide dehydrogenase (E3) component, and
related enzymes - Nostoc punctiforme PCC 73102
Length = 472
Score = 137 bits (332), Expect = 5e-31
Identities = 132/452 (29%), Positives = 203/452 (44%), Gaps = 35/452 (7%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T YD +IGGG G A V G K +++ +GG C+N+ CIP K
Sbjct: 5 TQHYDDIIIGGGKAGKTLAPALVADGRKTALVERSLNM-------IGGGCINIACIPTKT 57
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPA--LTEAVQNHIKSVNWVTRVDLR--EK 132
M +A + ++ + AYG +K N P L E +Q V ++L E
Sbjct: 58 MVASANVANTVRNSAAYG--------VKANTPIVDLAEVIQRKRAVVQSAREMNLHNLET 109
Query: 133 KID--YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISS 189
+D + G F T+ T G + +TA+ + I G RP P IPG E ++S
Sbjct: 110 ALDKNLIIGEARFVAPKTIEVTTTEGKNRLLTAERLFINTGTRPLIPSIPGLTEVEFLTS 169
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSE 248
+ I L + P +V+G+GYIGLE A G TV+ +S L D +A AV +
Sbjct: 170 ESIMELEYLPEHLIVLGSGYIGLEFAQMFRRFGCGVTVIGQSEQILSQQDPDIAIAVQTL 229
Query: 249 MEQKGVVFHNKCVPLSVEKLETGQLKARWQN---TETQERGEDVF---DTVLMATGRYAL 302
+E+ G+ F K L V + + L+ R N + Q ++ +L+A GR
Sbjct: 230 LERNGIEFLLKAKVLRVVR-KASPLENRTGNETILQIQVGDREITLQGSHLLVAVGRAPN 288
Query: 303 TKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRM 362
T +LNL AAGV + + + +TN+ I+A+GD+ G P+ T +++ R++ +
Sbjct: 289 TDSLNLAAAGVATDTRGFIQVNDRLETNIPGIWALGDI-NGGPQYTHISLDDYRIIKANL 347
Query: 363 FAGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRN 422
G + V + +F E VGL+E A + A +V A P + Q
Sbjct: 348 IDGGDRSTGDRLVPSCLFIAPELAHVGLTETEAQQQGYAIRVAKIDASAVPRARTLGQ-- 405
Query: 423 IRNCYLKAVALREAPQRILGLHFVGPVAGEVI 454
+ LKA+ E RILG + AGEVI
Sbjct: 406 -TDGLLKAIMDTET-GRILGCSLLCHEAGEVI 435
>UniRef50_Q88SV9 Cluster: Glutathione reductase; n=10;
Lactobacillales|Rep: Glutathione reductase -
Lactobacillus plantarum
Length = 444
Score = 137 bits (332), Expect = 5e-31
Identities = 116/371 (31%), Positives = 167/371 (45%), Gaps = 30/371 (8%)
Query: 14 LAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP 73
+ YDYD+ IG G A G +V V++ G +GGTC N GC
Sbjct: 1 MTNKYDYDVLYIGAGHATFDGAAPLAKTGVRVGVIE------SGL---IGGTCPNRGCNA 51
Query: 74 KKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK 133
K + + L E + S A INW A Q I + L +
Sbjct: 52 KITLDEPVKL---TRETARLNDILSS--APTINWTANVAHKQEIIDPLPAGLTARLEDGG 106
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIF 193
++G FKDAHT++ ++ ITA+ IVIA G +PH DIPG + S D
Sbjct: 107 ATIIHGHATFKDAHTVVVD----DQQTITAEKIVIATGLKPHRLDIPGT-KLAHDSSDFM 161
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQK 252
+L P +++GAGYIG+E A N+ G TV++ LR F Q V ++ ++
Sbjct: 162 NLKRLPQSIVIIGAGYIGMEFATIANAAGAQVTVMLHGDQALRDFYQPFVAQVVDDLTER 221
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
GV F + K + Q + + + + + D +L ATGR L L+ G
Sbjct: 222 GVTFIKNANVQAFTK-QDDQFQVSYGDHQ-----QLTTDWILDATGRIPNLDGLGLDRIG 275
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGK-PELTPVAIHAGRLLARRMFAGATQ-PM 370
V G + + QTNV NIYA GDVL P++TP A + L R+F+G T P+
Sbjct: 276 VK-YDRHGVYVNDHLQTNVPNIYAAGDVLANDLPKVTPAAYFESKYL-MRLFSGQTSAPI 333
Query: 371 DYDNVATTVFT 381
DY + + VFT
Sbjct: 334 DYPVIPSVVFT 344
>UniRef50_A0M205 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Gramella
forsetii (strain KT0803)
Length = 473
Score = 137 bits (332), Expect = 5e-31
Identities = 111/381 (29%), Positives = 172/381 (45%), Gaps = 26/381 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
+L +IG G GG A A A +LG KVT++D P+ GG C+ GCIP K +
Sbjct: 8 ELIIIGAGPGGYAAAFRAADLGLKVTLID-----PEANP---GGVCLYRGCIPSKALLHI 59
Query: 81 ALLGESIHEAVAYG--WEVPSLDAIKIN-WP-ALTEAVQNHIKSVNWVTRVDLREKKIDY 136
A + + +A +G +E P +D K+ W ++ E + + + ++ + KKIDY
Sbjct: 60 AKVKQEAMQAAEWGIEFESPKIDLKKLQKWKDSVVEKLTDGLGQLS-------KSKKIDY 112
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGG-RPHYPDIPGAVEYCISSDDIFSL 195
+ G EF + E+ +N++++ G P I + I S D L
Sbjct: 113 IKGTAEFISDKKIKVNPVEEDPYELEFENLILSTGSVNVSLPGIEIDHKKVIDSKDALDL 172
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGV 254
P LV+G GYIGLE +LG +V + S L G D+ + E + +
Sbjct: 173 NKIPKSMLVIGGGYIGLELGSVYAALGSKVSVAEMTSGFLPGADRDLVNVFEKEHPFEAL 232
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
F K SV K ++KA + + + + E FD +L+A GR TKTL L A +
Sbjct: 233 YFDTKVEKASVTK---NKVKATLKGKDDKTK-EKTFDQILVAVGRKPNTKTLALNMANIE 288
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
N + QT NIYA+GD L G+P L A + G++ + D +
Sbjct: 289 PDENGFLKVNRQRQTKKKNIYAIGD-LTGEPLLAHKATYEGKVAVETIAGEKGAAYDPKS 347
Query: 375 VATTVFTPLEYGCVGLSEETA 395
+ VFT + GL++E A
Sbjct: 348 IPAIVFTNPQMAWCGLTQEEA 368
>UniRef50_Q6MC87 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Dihydrolipoyl dehydrogenase - Protochlamydia amoebophila
(strain UWE25)
Length = 465
Score = 137 bits (331), Expect = 7e-31
Identities = 124/440 (28%), Positives = 204/440 (46%), Gaps = 28/440 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
YDLAV+G G GG A A +G K +D + LGGTC+NVGCIP K L+H
Sbjct: 5 YDLAVVGAGPGGYVAAIRAAQMGLKTICID--------KRETLGGTCLNVGCIPSKTLLH 56
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
L + EV L K+N+ L E +N +K + + ++ + Y+
Sbjct: 57 STDLYSTLKQHGLEQAIEVSDL---KVNFTKLMERKRNVVKGLIEGIALLFKKNGVIYLK 113
Query: 139 GLGEFKDAHTLIATLKNGSK-KEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLG 196
G +F DAHTL +KNG+ EI A I++A G P +P + +SS +L
Sbjct: 114 GEAQFLDAHTL--QVKNGTHIDEIKANYILLATGSESTSLPHLPFDEKNIVSSTGALNLA 171
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPL-RGFDQQMAQAVTSEMEQKGVV 255
P + LV+G G IG+E A N LG T++ S L D +++ + ++++G+
Sbjct: 172 TVPPRLLVIGGGVIGVELASVYNRLGSSVTIIEMSDRLCPAMDIALSKYLFQILKKQGIE 231
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
++ + QN + Q +V VL+A GR T+ L L+ G+
Sbjct: 232 IKLSTKMMTAVLQPNETILTIEQNEQLQNISGEV---VLVAVGRRPYTQGLALDKVGIQ- 287
Query: 316 VSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ G I + +T+ +I+A+GD++EG L A G + G Q ++Y
Sbjct: 288 IDKKGFIPVDGFFRTSQPHIFAIGDLIEG-VMLAHRASQEG-ITVVEWLKGERQSINYLA 345
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
+ V+T E VGL+E+ A + G + +++ I ++K + +
Sbjct: 346 IPNVVYTNPEVASVGLTEQEA-SESGLTLL-TGTTYFRGNSRARCTDEIEG-FVKLIGEK 402
Query: 435 EAPQRILGLHFVGPVAGEVI 454
++ R+LG+H +G A E+I
Sbjct: 403 KS-GRLLGMHIIGAHASELI 421
>UniRef50_A3UIQ0 Cluster: Probable glutathione reductase; n=1;
Oceanicaulis alexandrii HTCC2633|Rep: Probable
glutathione reductase - Oceanicaulis alexandrii HTCC2633
Length = 449
Score = 136 bits (329), Expect = 1e-30
Identities = 124/448 (27%), Positives = 195/448 (43%), Gaps = 36/448 (8%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
DL V+G G+ G+A A A G VT+++ +GGTC GC+PKK++ A
Sbjct: 6 DLLVLGTGNAGMAAAGVAQRAGKSVTLVE---------SGDVGGTCAIRGCVPKKVLVAA 56
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
A ++I A + S+ +K++WPAL + + ++ V + R + + + V+G
Sbjct: 57 AANLDAIARASDHAI---SVGEVKLDWPALIKRERTFVEGVPEMFRASITNRGMALVSGK 113
Query: 141 GEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPPG 200
F + + + + TA IVIA G +P I G +SDD+ +L P
Sbjct: 114 AVFTGPNAI-----DVEGETYTADRIVIATGSKPAQLPIEGWA-LTATSDDLLTLETLPK 167
Query: 201 KTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFHNK 259
+ + VG G I LE A + G T+L S L D+ M + + GV
Sbjct: 168 EVVFVGGGVIALEFAHIMVRAGAKVTILEAASRVLPRLDEDMVDTLVAHTRSLGVTIQTG 227
Query: 260 CVPLSVEKLETGQLKARWQNTETQERGEDVF---DTVLMATGRYALTKTLNLEAAGVTCV 316
++ E G +A E GE + D V+ GR + L+LEA G+
Sbjct: 228 VSVRAIR--EDGARRA----VEVVIDGETLSLSADLVVNGAGRRPAVEDLDLEAGGIR-- 279
Query: 317 SNSGKIIAETEQTNVSN--IYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
S+ G I + +++N +Y GD L P+++PVA + GR+ A + DY +
Sbjct: 280 SDRGHIEVDVNLRSLTNPSVYVAGDALAASPQMSPVASYEGRIAGENAINDAKESPDYSS 339
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
+ + V+T VGL E A A V+V ++ + V +
Sbjct: 340 IPSAVYTVPAIASVGLDEAGAQAAGLEPVVKVNDM----RDWRSAKTYAEQVAFAKVLID 395
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
A RILG H G A EVI F A+K
Sbjct: 396 PATDRILGAHLAGHGAEEVIHLFTLAMK 423
>UniRef50_Q834J0 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Lactobacillales|Rep: Dihydrolipoyl dehydrogenase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 469
Score = 136 bits (328), Expect = 2e-30
Identities = 106/387 (27%), Positives = 184/387 (47%), Gaps = 35/387 (9%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
DL ++GGG+GG A A G VT+++ K+ LGGTC++ GCIP K + ++
Sbjct: 6 DLLILGGGTGGYVAAIRAAQKGLNVTIVE---------KYKLGGTCLHKGCIPTKALLRS 56
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
A + +++ +A ++G E +A I++ + + + I+ ++ ++ KI + G
Sbjct: 57 AEVFDTLKQAASFGIET---EAASIDFSKIQQRKEGIIEQLHKGVEGLCKKNKIKILAGE 113
Query: 141 GE------FKDAHTLIATLKNGSKKE---ITAKNIVIAVGGRPH-YPDIPGAVEYCISSD 190
G F +A N +E I KN++IA G P++P E+ +SSD
Sbjct: 114 GAILGPSIFSPVSGAVAVTFNDPTREEEIIVPKNVIIATGSSSKTLPNLPLDEEFILSSD 173
Query: 191 DIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEM 249
+ L P ++G G IG+E A LNSLG T++ L +++ + +
Sbjct: 174 GMLELEELPESIAIIGGGVIGVEWASLLNSLGVNVTIIEFLDRLLINESATISKELKKRL 233
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVF--DTVLMATGRYALTKTLN 307
EQ+G+ N + V+ + K Q + + G++ D V++A GR L
Sbjct: 234 EQRGI---NILLGSKVQ-----EAKVTGQKVQVEVAGQETLTVDKVMVAIGRQPNINKLG 285
Query: 308 LEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT 367
L+ V ++ G + E QT +IYA+GD ++ +L VA+ G L + +
Sbjct: 286 LQNTSVK-YTDKGIEVNEFYQTTEGHIYAIGDCID-TLQLAHVAMKEGELAVQHLLGETV 343
Query: 368 QPMDYDNVATTVFTPLEYGCVGLSEET 394
+P++Y NV V+T E VG + ET
Sbjct: 344 EPLNYTNVPRGVYTNPEIASVGYTRET 370
>UniRef50_O66945 Cluster: Dihydrolipoyl dehydrogenase; n=2; Aquifex
aeolicus|Rep: Dihydrolipoyl dehydrogenase - Aquifex
aeolicus
Length = 465
Score = 136 bits (328), Expect = 2e-30
Identities = 122/449 (27%), Positives = 194/449 (43%), Gaps = 30/449 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
++DL ++G GSGG A G KV +V SP+ +GG C+N GCIP K M
Sbjct: 2 EFDLIIVGAGSGGYEAGLYAFRRGMKVA---FVELSPET----VGGNCLNRGCIPSKYMR 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A L + + YG D I + L E N + ++ + ++ +I
Sbjct: 55 HGAYLLDKFQKMEQYGIISKGYD---IEYKKLKEGRDNVVVTIRENFKKFAQQLRIPIYY 111
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGH 197
G G KD +T+ G ++ + AK I++A G P ++ +Y I +D I+ + +
Sbjct: 112 GKGVLKDPNTVFV---EGPEETLKAKYILVATGSSPTSVGNLVPDGKYVIDTDQIWEIDY 168
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLV----RSVPLRGFDQQMAQAVTSEMEQKG 253
P K L+VG G +G+E A G VLV R +P + + + ++ + G
Sbjct: 169 VPKKVLIVGGGAVGVEFAYIFRKYG-SEVVLVEIKDRLLPTPDIPEDSGRYLARKLRELG 227
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
V + S EK + G +KA+ + E V D +L+ GR TK + LE G+
Sbjct: 228 VDIRTRTSVESWEKTQNG-VKAK-----LTDGSEVVADFILLGVGRKPNTKGIGLEELGI 281
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
E QTN+ NIYA GD+ L +++ G++ + +
Sbjct: 282 EMDERGFVKTNEYAQTNIPNIYACGDI-TSPLMLAHKSMYEGKIAVSHILGERDWKKNER 340
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ +++ LE VGL+EE A +V V P +++ VA
Sbjct: 341 IIPKIIYSALEVASVGLTEEQAEDEDIEVRVGVASFVSNPKAM---DDGENEGFVRIVAD 397
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
E + ILG H VGP AGE+I +K
Sbjct: 398 DETGE-ILGCHIVGPHAGELIHQVVHMIK 425
>UniRef50_Q1R3M3 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Escherichia coli|Rep: Dihydrolipoyl dehydrogenase -
Escherichia coli (strain UTI89 / UPEC)
Length = 472
Score = 135 bits (327), Expect = 2e-30
Identities = 117/445 (26%), Positives = 202/445 (45%), Gaps = 17/445 (3%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
+D+AV+GGG GG A A G V +D + QG GGTC+NVGCIP K L+
Sbjct: 5 FDVAVMGGGPGGYVAALRAAQNGLSVVCIDDGV-NAQGEP-SPGGTCLNVGCIPSKSLLQ 62
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ L + HEA +G V + + N A+ + + + + ++ K+ ++
Sbjct: 63 SSELYAQVQHEASIHGVNV---EGVSFNAAAMIQRKDAIVSRLTMGISLLFKKNKVKHLC 119
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHY-PDIPGAVEYCISSDDIFSLGH 197
GL + A I L+ + I A+N+VIA G +P P + + + + +L
Sbjct: 120 GLATLERAQDEIWQLRVNDQ-HIHARNVVIATGSQPRQLPGVTIDNQQILDNRGALALSE 178
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVF 256
P + V+GAG IGLE N +G T+L + L + +++ V M G+
Sbjct: 179 VPPRLGVIGAGVIGLELGSVWNRVGSDVTLLEMAPTFLPALEARLSNEVRKAMIASGMKM 238
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
++E+ + G + RW+ E +E E FD +++A GR ++L G+
Sbjct: 239 QLAVEIEAIEQRDDG-VHVRWRQGEKRE--ESRFDKLILAIGRVPRLSGVDLVQLGLEAD 295
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ G + +T + ++A+GDV+ G P L A+ G ++A ++ A +P+++ +
Sbjct: 296 NRGGIAVDNLCRTGKAGLWAIGDVVRG-PMLAHKAMAEGVVVADQIAGLAVEPINFALIP 354
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+ ++T E VG E +L G + F + C L + +
Sbjct: 355 SVIYTQPEVAWVG-ENEASLKAAGRVFNKGNSLFAGNGRALALGQEGGRCTLYS---DKH 410
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAV 461
R+LG VGP A E+I A A+
Sbjct: 411 TDRVLGGAIVGPQASELINEIALAM 435
>UniRef50_Q03GQ4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide dehydrogenase (E3) component,
related enzyme; n=1; Pediococcus pentosaceus ATCC
25745|Rep: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide dehydrogenase (E3) component,
related enzyme - Pediococcus pentosaceus (strain ATCC
25745 / 183-1w)
Length = 452
Score = 135 bits (327), Expect = 2e-30
Identities = 114/409 (27%), Positives = 197/409 (48%), Gaps = 39/409 (9%)
Query: 63 GGTCVNVGCIPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWP-ALTE--AVQNHIK 119
GGTC+N+ CIP KL+++ + + P + +K N+ A+T+ +V ++
Sbjct: 40 GGTCINIACIPSKLLYELS--------------DKPQVGGLKDNYKMAITKKRSVIGKLR 85
Query: 120 SVNWVTRVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDI 179
N+ D +K + +NG F D HTL NG+ +E+ + I I G PDI
Sbjct: 86 YSNFHKLAD--QKTVKVLNGSASFIDQHTLNVKYLNGATEEVVGERIFINTGATSTIPDI 143
Query: 180 PGAVE--YCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRG 236
PG E ++S D+ H P ++G GYIG+E A + G T++ R+ +RG
Sbjct: 144 PGLKESSRTVTSTDLLDQDHFPQSLAIIGGGYIGMEFATTYSQFGSKVTMINRNAEFMRG 203
Query: 237 FDQQMAQAVTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMA 296
DQ ++QAV ++ G+ + V+ + G ++ E + + D +L+A
Sbjct: 204 MDQDVSQAVKQNFDKAGIEVLQSAEVIRVQ--DQGSHAVLTVASDGSE-SQIMVDMILVA 260
Query: 297 TGRYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGR 356
TGR + LNLE AG+ + +G + + +TNV NI+A+GDV G + T +++ R
Sbjct: 261 TGRKPNIQGLNLEQAGIR-YTEAGVAVDDHLRTNVQNIWAMGDV-RGGAQFTFLSLDDYR 318
Query: 357 LLARRMFAGATQPMDYD-NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTE 415
++ +++A T+ + V T+F +G+SE AL DK ++ + K
Sbjct: 319 IVYNQLYASGTKTTEEQVIVPKTIFLMPPLSQIGMSEREAL-----DK-KIEYRTGKVAV 372
Query: 416 FFIPQRNI---RNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+P+ +I N + K + +E ILG P A E+I + A+
Sbjct: 373 AGMPKAHILGHPNGFYKVLIDKE--DHILGATIYAPEAHEIINIISLAM 419
>UniRef50_A7CW98 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Opitutaceae
bacterium TAV2|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Opitutaceae
bacterium TAV2
Length = 474
Score = 135 bits (327), Expect = 2e-30
Identities = 132/452 (29%), Positives = 197/452 (43%), Gaps = 32/452 (7%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK- 75
T+ +DL VIGGGS G A+ A LG V ++D +P LGG C+ GC+P K
Sbjct: 6 THIHDLIVIGGGSAGFNAARVASGLGKNVAIVD---GAPD-----LGGLCILRGCMPSKT 57
Query: 76 LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKID 135
L+H A +L + H G P I+ AL + I + ++ +
Sbjct: 58 LLHAADVLHHARHGG-KLGIRAPGAS---IDMRALHRWKKKVIGEFSDYRVQAMQSGRYT 113
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCI-SSDDIFS 194
F D+HTL L NG + + I+IA G R P IPG + +SDD+
Sbjct: 114 LHRSHARFIDSHTL--KLDNGDS--LRGQKILIATGSRVSVPPIPGLDDTPHWTSDDVLD 169
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKG 253
L + P +V+G G + E A FLN +G T++ RS LR + A V +G
Sbjct: 170 LDYVPESVIVLGGGIVACELAQFLNRIGSKVTLIQRSPHLLREHSPEAADVVAQAFRDEG 229
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ H LSV Q++ +++ + + A GR T LNL+AAGV
Sbjct: 230 IRLHTGTRILSVSGENGRQVRVVFEHPHLNKTHTCRARHLFNALGREPATDGLNLDAAGV 289
Query: 314 TCVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG------A 366
+ G+I + +QT +IYA GDV G E+ +A+ G L AR F
Sbjct: 290 -ALDERGRIRVNRWQQTTQPHIYAGGDVC-GPHEIVHLAVAQGELAARHAFGARLPSGKP 347
Query: 367 TQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNC 426
+P+D + VFT +G +E L + G V + F + + +
Sbjct: 348 LKPIDESLLLGVVFTDPALATIGW-QEHLLRKRGQPFVAASYPFNDHGKSIVMDATYGHV 406
Query: 427 YLKAVALREAPQRILGLHFVGPVAGEVIQGFA 458
+ A +R R+LG VG AGE+I F+
Sbjct: 407 KVIADPVR---GRLLGAEIVGRDAGELIHAFS 435
>UniRef50_A3XHA5 Cluster: Regulatory protein; n=4;
Flavobacteriaceae|Rep: Regulatory protein -
Leeuwenhoekiella blandensis MED217
Length = 503
Score = 135 bits (327), Expect = 2e-30
Identities = 125/446 (28%), Positives = 195/446 (43%), Gaps = 32/446 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIG G+ G A +AV G V + D GGTC N GC PKK++
Sbjct: 59 YDLFVIGTGNAGKHVAYDAVEAGLNVAIAD---------NREFGGTCANRGCDPKKVLVG 109
Query: 80 AALLGESIHEAVAYGW-EVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ E G EVP ++ W L E + +V + T L+++ I +
Sbjct: 110 LTEIIERSQNLKGKGIAEVP-----EVRWSDLMEFKKTFTGAVPFTTEEKLKDQGITLYH 164
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
+F D +TL K +TA IVIA G P + +IPG E+ + SDD L
Sbjct: 165 QSPKFLDENTLSV-----EGKTVTADKIVIATGNIPMHLNIPGD-EHTLISDDFLELEAL 218
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P + +GAGYIG+E A G T++ V + L FD+ +A + + E+ G+ F
Sbjct: 219 PESIIFIGAGYIGMEFAHIAARCGVDVTIVDVNARILSNFDEDLALQLQKKSEELGIKFL 278
Query: 258 NKCVPLSVEKL-ETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
++EKL + +L + + E +F+T GR L+LE V
Sbjct: 279 FNAEAKAIEKLRKNHRLTVDHNGNSEKLKAELIFNT----AGRVPAVDELDLEKGNVAFS 334
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLE-GKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
+ + T ++YA GDV + LTPVA +++ + G + +D
Sbjct: 335 KKGVAVNTFMQSTTNPSVYACGDVSDTSNLPLTPVAHQEAYYVSKNILNGNSAEVDVPAT 394
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
+ VFT + VGL+E+ A + G D EV A + +++ +R Y + +
Sbjct: 395 PSVVFTIPQLASVGLTEQEA-QKQGYD-FEVKTASVE--DWYNAKRLNETHYAYKTLVDK 450
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAV 461
++LG H + A E I F A+
Sbjct: 451 KTGQLLGAHLLSSEAAETINLFMMAM 476
>UniRef50_Q11LG9 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=31;
Alphaproteobacteria|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor -
Mesorhizobium sp. (strain BNC1)
Length = 475
Score = 135 bits (326), Expect = 3e-30
Identities = 127/451 (28%), Positives = 209/451 (46%), Gaps = 44/451 (9%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+ VIG GSGGL A A +LGA V +++ + +GG C+N GC+P K + +
Sbjct: 8 DICVIGAGSGGLTVAAAAASLGASVVLIE---------RGKMGGDCLNYGCVPSKALIAS 58
Query: 81 ALLGESIHEAVAYGWEV--PSLDAIKINWPALTEAVQNHIK-SVNWVTRVDLREK----K 133
A + + G PS+D + V HI+ ++ + D +E+
Sbjct: 59 ARQAHRLSHGGSLGIAAVEPSIDFAR---------VAGHIEQAIAAIAPNDSKERFTALG 109
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDI 192
++ ++ G FKD T++A GS EI A+ VIA G P P IPG + ++++
Sbjct: 110 VEVISAQGHFKDPRTVVA---GGS--EIRARRFVIATGSSPAIPPIPGLSDVPFLTNETT 164
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQK 252
F L P ++VG G IG+E A LG TVL L D ++A V + ++
Sbjct: 165 FGLKQSPAHLIIVGGGPIGMERAQAHRRLGADVTVLEADTVLGKEDPELALGVKQALLKE 224
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFD--TVLMATGRYALTKTLNLEA 310
GV VE+ + ++ E+G D +L+ATGR + L LE
Sbjct: 225 GVAILEHARAERVERYKGTGIRVH----VADEKGAHSIDGSHLLIATGRRPNVEALALEN 280
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
AGV G I+ +T I+A+GDV G P+ T VA + L+ R +
Sbjct: 281 AGV-AYGPGGITISPKLRTTNRRIFAIGDV-AGGPQFTHVANYHAGLVIRAILFRLPVKA 338
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
+++++ FT E +GL+E A R G +V+V + + + + + + ++K
Sbjct: 339 NHEHIPRVTFTDPELAQIGLTENEA-RRRGL-QVKVLRSSFSENDRAHAEGH-TDGFIKL 395
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ R RILG+ +G AGE++ ++ A+
Sbjct: 396 IVGRRG--RILGVSILGRGAGEMMHFWSLAL 424
>UniRef50_A7JHZ5 Cluster: Soluble pyridine nucleotide
transhydrogenase; n=11; Francisella tularensis|Rep:
Soluble pyridine nucleotide transhydrogenase -
Francisella tularensis subsp. novicida GA99-3549
Length = 471
Score = 135 bits (326), Expect = 3e-30
Identities = 121/445 (27%), Positives = 191/445 (42%), Gaps = 45/445 (10%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
Y+YD+ +IG G GG A +A G KV +++ +GG C N G IP K +
Sbjct: 8 YNYDIIIIGSGPGGEGAAMKATRNGQKVAIIE---------DDAIGGGCNNWGTIPSKAL 58
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
Q + V Y + ++P + + + + R +ID
Sbjct: 59 RQ-------LSREVWYNKK-------NFDFPEMLDTAYEIVIKQREIKRNRFANNEIDVF 104
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFSLG 196
G F D H + + KNGS + ITAK +++ G RP++P DI + SD + L
Sbjct: 105 YGFASFIDKHKIKISRKNGSTEIITAKKFILSTGSRPYHPDDIDFTHPRILDSDKLLELK 164
Query: 197 HPPGKTLVV-GAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSE--MEQK 252
K++ + GAG IG E A L +L ++ L F D ++ + +T+ + Q+
Sbjct: 165 DKNIKSITIYGAGVIGCEYASILGTLDIQVNLINTRNKLMSFLDDEIIETLTNHFTVNQR 224
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVF--DTVLMATGRYALTKTLNLEA 310
+ HN+ +KAR T + D VL A GR T LNL+
Sbjct: 225 INLIHNETYK---------SIKARGDKVVTTLNSGRIIESDYVLFALGRSGNTNGLNLDK 275
Query: 311 AGVTCVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
GV G + + + QT NIYAVGDV+ G P L A + GR A + G+
Sbjct: 276 IGVEYDPQRGLVKVNDNYQTTQENIYAVGDVI-GFPSLASSAFNQGRFAATHIIDGSCND 334
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
+++ T ++T E C+G +EE A + EV A++K + Q + +
Sbjct: 335 KLVEDIPTGIYTRPEISCIGKTEEQLTAEN--IPYEVGRAYFK--DLARAQISGSETGML 390
Query: 430 AVALREAPQRILGLHFVGPVAGEVI 454
+ + ILG+H G E+I
Sbjct: 391 KILFHKETLEILGIHCFGHRVSEII 415
>UniRef50_Q4FXL9 Cluster: Dihydrolipoamide dehydrogenase, putative;
n=4; Trypanosomatidae|Rep: Dihydrolipoamide
dehydrogenase, putative - Leishmania major strain
Friedlin
Length = 508
Score = 135 bits (326), Expect = 3e-30
Identities = 117/459 (25%), Positives = 202/459 (44%), Gaps = 25/459 (5%)
Query: 11 KNILAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVG 70
+ I+A T +D+ V+GGG G+A A A LG K +++ + +GG G
Sbjct: 3 RTIVAWTRKFDVCVLGGGPAGIAAAVRAYELGKKACIIE---------ESRIGGADFWNG 53
Query: 71 CIPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLR 130
+ K + + A ++ + ++ KI L +A+ N ++ T L
Sbjct: 54 ALQSKTLWEMAKFARYTMGNTSHRFMKSVIELPKIKHSNLIKAITNAAETRETQTLEVLA 113
Query: 131 EKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISS 189
I+ ++GLG FK +++ T K+G+++ + A VIA G P +P + +S
Sbjct: 114 NAHIEVLSGLGSFKTPNSVAVTKKDGTEETVEADYFVIATGAHPRPHPTAVADGKVVFTS 173
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV----RSVPLRGFDQQMAQAV 245
DDI + P +++GAG IG E A + G ++ R +P+ D+ +A V
Sbjct: 174 DDIM-MQPLPKSIVIIGAGVIGCEFASIFANFGVTQVNIIEKSGRILPME--DEDIALFV 230
Query: 246 TSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKT 305
+ +EQKGV FH+ + + G+ ++ + V D+ L++ GR
Sbjct: 231 QTLLEQKGVCFHHHSA-MESSSINDGKFHYTLRDVRDNSLHQHVTDSALVSIGRVPAISK 289
Query: 306 LNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG 365
LNLEA G+T N +IYA GD + L VA GR M+
Sbjct: 290 LNLEAIGITVKGNRIDRDEFLRIEPHKHIYACGDTCT-RVALVNVAELEGRACIDHMYTP 348
Query: 366 ATQ---PMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRN 422
+ + DN++T +F E VGL+E+ + K+ Y Y+ + N
Sbjct: 349 YPEEQLKLKLDNLSTIMFLDQEVAAVGLNEQQCQKMSISYKMARYS--YEYVGRALAMGN 406
Query: 423 IRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
R ++K V + ++LG+ VGP A +I+ + A+
Sbjct: 407 TRG-FIKLVVTNDKKMQVLGVRAVGPHASSIIELASLAI 444
>UniRef50_P66007 Cluster: Probable soluble pyridine nucleotide
transhydrogenase (EC 1.6.1.1) (STH) (NAD(P)(+)
transhydrogenase [B-specific]); n=19; Bacteria|Rep:
Probable soluble pyridine nucleotide transhydrogenase
(EC 1.6.1.1) (STH) (NAD(P)(+) transhydrogenase
[B-specific]) - Mycobacterium bovis
Length = 468
Score = 134 bits (325), Expect = 4e-30
Identities = 114/356 (32%), Positives = 163/356 (45%), Gaps = 28/356 (7%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ VIG G GG A + LG V +++ +G LGG CVN G IP K +
Sbjct: 3 EYDIVVIGSGPGGQKAAIASAKLGKSVAIVE------RGRM--LGGVCVNTGTIPSKTLR 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHI--KSVNWVTRVDLREKKIDY 136
+A L +++ YG D I PA A H+ K V+ V R L ++D
Sbjct: 55 EAVLYLTGMNQRELYGASYRVKDRIT---PADLLARTQHVIGKEVD-VVRNQLMRNRVDL 110
Query: 137 VNGLGEFKDAHT-LIATLKNGSKKEITAKNIVIAVGGRPHYPD-IPGAVEYCISSDDIFS 194
+ G G F D HT L+ K +T I+IA G RP P + E + SD I
Sbjct: 111 IVGHGRFIDPHTILVEDQARREKTTVTGDYIIIATGTRPARPSGVEFDEERVLDSDGILD 170
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKG 253
L P +VVGAG IG+E A +LG TV+ + + F D ++ +A+ +
Sbjct: 171 LKSLPSSMVVVGAGVIGIEYASMFAALGTKVTVVEKRDNMLDFCDPEVVEALKFHLRDLA 230
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAG 312
V F +V+ G + T G+ + +TV+ + GR T L+L AG
Sbjct: 231 VTFRFGEEVTAVDVGSAGTVT-------TLASGKQIPAETVMYSAGRQGQTDHLDLHNAG 283
Query: 313 VTCVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT 367
+ V G+I + QT V +IYAVGDV+ G P L ++ GRL A F T
Sbjct: 284 LE-VQGRGRIFVDDRFQTKVDHIYAVGDVI-GFPALAATSMEQGRLAAYHAFGEPT 337
>UniRef50_P54533 Cluster: Dihydrolipoyl dehydrogenase; n=41;
Firmicutes|Rep: Dihydrolipoyl dehydrogenase - Bacillus
subtilis
Length = 474
Score = 134 bits (325), Expect = 4e-30
Identities = 125/455 (27%), Positives = 220/455 (48%), Gaps = 47/455 (10%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ ++GGG+GG A A LG K V++ K LGGTC++ GCIP K +
Sbjct: 4 EYDVVILGGGTGGYVAAIRAAQLGLKTAVVE---------KEKLGGTCLHKGCIPSKALL 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
++A + + EA +G E + +N+ + + Q + + +++ KID
Sbjct: 55 RSAEVYRTAREADQFGVETA---GVSLNFEKVQQRKQAVVDKLAAGVNHLMKKGKIDVYT 111
Query: 139 GLGEFKDAH-------TLIATLKNGSKKE-ITAKNIVIAVGGRPH-YPDIPGAVEYCISS 189
G G T+ NG + + + K ++IA G RP P + + ++S
Sbjct: 112 GYGRILGPSIFSPLPGTISVERGNGEENDMLIPKQVIIATGSRPRMLPGLEVDGKSVLTS 171
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV---RSVPLRGFDQQMAQAVT 246
D+ + P ++VG G IG+E A L+ G TV+ R +P D ++++ +
Sbjct: 172 DEALQMEELPQSIIIVGGGVIGIEWASMLHDFGVKVTVIEYADRILPTE--DLEISKEME 229
Query: 247 SEMEQKGVVFHN--KCVPLSVEKLETGQLKARWQNTETQERGEDV---FDTVLMATGRYA 301
S +++KG+ F K +P ++ K + + ++ GE V + +L++ GR A
Sbjct: 230 SLLKKKGIQFITGAKVLPDTMTKTSDD------ISIQAEKDGETVTYSAEKMLVSIGRQA 283
Query: 302 LTKTLNLEAAGVTCVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLAR 360
+ + LE + V+ +G I + E+ QT S+IYA+GDV+ G +L VA H G ++A
Sbjct: 284 NIEGIGLENTDI--VTENGMISVNESCQTKESHIYAIGDVIGGL-QLAHVASHEG-IIAV 339
Query: 361 RMFAGAT-QPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIP 419
FAG P+D V +++ E VGL+E+ A A K+ + F + +
Sbjct: 340 EHFAGLNPHPLDPTLVPKCIYSSPEAASVGLTEDEAKANGHNVKIGKF-PFMAIGKALVY 398
Query: 420 QRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVI 454
+ + ++K VA R+ ILG+H +GP ++I
Sbjct: 399 GES--DGFVKIVADRDTDD-ILGVHMIGPHVTDMI 430
>UniRef50_Q7UVC8 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Rhodopirellula baltica
Length = 474
Score = 134 bits (324), Expect = 5e-30
Identities = 127/458 (27%), Positives = 209/458 (45%), Gaps = 35/458 (7%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK- 75
T ++L ++GGG G A A LG V +D +P+ GGTCV VGCIP K
Sbjct: 3 TARHELVILGGGPAGYVAAIRAAQLGIDVACID---DNPR-----FGGTCVRVGCIPSKA 54
Query: 76 LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKID 135
L+ + L E+ H+ +G V + ++++ + + + ++S+ + + +
Sbjct: 55 LLESSHLYEEAQHKFADHGLNVSN---VEVDLDVMMKRKEKIVESLTGGIDMLFDRRGVT 111
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKE----ITAKNIVIAVGGRP-HYPDIPGAVEYCISSD 190
+G G +D ++ T G+ ++ +TA I++ G P P + + +S
Sbjct: 112 AYHGRGRLRDVDSIEITPSEGAAEDQPTLVTADQIMLCPGSVPAQLPFVEEDGDRIGNST 171
Query: 191 DIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV---RSVPLRGFDQQMAQAVTS 247
S P + +V+G GYIGLE N LG VL R +P G D++MA
Sbjct: 172 TALSFPEVPEELVVIGGGYIGLELGSVWNRLGSNVIVLEAFDRIMP--GLDKEMATLAHR 229
Query: 248 EMEQKGVVFHNKCVPLSVE-KLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKT 305
+++G+ S + + G K + GE + D VL+ATGR TK+
Sbjct: 230 SFKKQGMDIRTGTFVASAKVDPKPGDKK---PCVIKIKNGETIRCDRVLLATGRAPATKS 286
Query: 306 LNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG 365
+ LE AGV + +T+V+ IYA+GD + G L A+ G + +M AG
Sbjct: 287 MGLEEAGVKLDERGFIQVNHQFETSVTGIYAIGDCI-GGAMLAHKAMEEGIVCVEQM-AG 344
Query: 366 ATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRN 425
M+Y+ + VFT E VG +EE L G + Y+ P R + +
Sbjct: 345 IASEMNYEVIPAIVFTHPEIAMVGKTEE-ELKEAGIE----YNKGVCPLGANGRARTLGD 399
Query: 426 CYLKAVALRE-APQRILGLHFVGPVAGEVIQGFAAAVK 462
+ L + A R+LG+H +GP AG++I AAA++
Sbjct: 400 IDGRVKILADAATDRVLGVHIIGPRAGDMIAEAAAAME 437
>UniRef50_A3U327 Cluster: Regulatory protein; n=4;
Alphaproteobacteria|Rep: Regulatory protein - Oceanicola
batsensis HTCC2597
Length = 449
Score = 134 bits (324), Expect = 5e-30
Identities = 139/451 (30%), Positives = 189/451 (41%), Gaps = 36/451 (7%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T YDL VIGGG+GG A+ A N G V +D P GGTC GC PKK+
Sbjct: 2 TKSYDLIVIGGGTGGNGVARMAANAGWSVASID---SEPH------GGTCALRGCDPKKM 52
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
+ E G E +NW + ++ ++ L + ID
Sbjct: 53 LIAVTEGVEWAENMKGKGLEAQP----SVNWSDMIAFKRSFTDAMPPRIEAGLEKAGIDV 108
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLG 196
++G F A NG + + AK+ IA G RP +IPG EY +S D L
Sbjct: 109 LHGEVRFTGPD---AIELNG--ETLRAKHFHIATGARPMTLNIPGE-EYLATSTDFLELP 162
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLG-YPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGV 254
P + VG G+I +E A G TVL + PL FD + + + GV
Sbjct: 163 ERPDRIAFVGGGFIAMEFAHVAKRAGAREVTVLEMMDRPLGNFDPDLVAMLVEATAELGV 222
Query: 255 VFHNKCVPLSVEKL--ETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
K +EK E R TET D V+ TGR LNLEAAG
Sbjct: 223 DLRTKAKVAKIEKQGDEVVVTVERHDGTET-----ITCDLVVHGTGRVPNIDGLNLEAAG 277
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGA-TQPMD 371
V K+ TN + I+A GD + LTPV+ GR+ + + G + +
Sbjct: 278 VEYSRRGIKVSDAMRATNPA-IFAAGDCADSGLNLTPVSAAEGRIAGKNILGGKDAREIK 336
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQR-NIRNCYLKA 430
Y + + VFT VGLSE A AR K +V+ F K ++ R ++ K
Sbjct: 337 YPPIPSVVFTLPMVATVGLSE--AAAREQGLKFDVH--FEKTEGWYSSLRVGAKHTGFKV 392
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ R + Q ILG H +GP A E I FA A+
Sbjct: 393 LVERGSGQ-ILGAHLIGPGAEEQINLFAMAM 422
>UniRef50_Q18ZH8 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Desulfitobacterium hafniense|Rep: Dihydrolipoyl
dehydrogenase - Desulfitobacterium hafniense (strain
DCB-2)
Length = 461
Score = 134 bits (323), Expect = 6e-30
Identities = 119/446 (26%), Positives = 205/446 (45%), Gaps = 28/446 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
Y + ++GGG GG CA A LG V +++ K LGGTC+N GCIP K + +
Sbjct: 4 YQVGILGGGPGGYVCALRAAQLGLSVVLVE---------KERLGGTCLNKGCIPTKTLVK 54
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A L I A +G + L +++P + + + ++ ++ KKI + G
Sbjct: 55 SAELWREIKHAEEFGIQ---LGGALLHYPQIAARKKEVVNTLVSGIEQLMKAKKITVLKG 111
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSDDIFSLGHP 198
GE K+A+ + T + G K E+ +N+V+A G P +PG + ++S+++
Sbjct: 112 WGEVKEANRIEVTTETG-KVELHVENLVLATGSIPTKIPVPGVDLPGVVTSEELLEQETL 170
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKGVVF 256
P +V+G G IGLE A + G +V V +P L D+++ + + +++ G+
Sbjct: 171 PDSLVVIGGGVIGLEFASIYHEFGVKVSV-VEMLPSLLPNIDEEIPKRLAPLLKRSGLEI 229
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
K ++ E G + +E VL+ATGR ++ +A G+
Sbjct: 230 LTKAFVREIKPKEEGLVVIVEDGKGLKELPA---QQVLLATGRRPSLSGIHGDALGLELD 286
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ K+ ++ QT+V +YA+GDV+ G L VA G + A M AG M+ +
Sbjct: 287 RGAIKVNSQM-QTSVPKVYALGDVV-GGAMLAHVASMQGMVAAEHM-AGQQVSMEGRAIP 343
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+ +FT E VG +E+ A KV + + + I +K +A E
Sbjct: 344 SAIFTYPEIAAVGETEQALKASGQNYKVSKFP--FSANGKALALGEIMG-LVKLLADEEG 400
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
++G +GP A +IQ AV+
Sbjct: 401 V--VIGASIMGPQASSLIQECVLAVE 424
>UniRef50_Q311Y4 Cluster: Mercuric reductase, putative; n=4;
Deltaproteobacteria|Rep: Mercuric reductase, putative -
Desulfovibrio desulfuricans (strain G20)
Length = 486
Score = 133 bits (322), Expect = 8e-30
Identities = 131/451 (29%), Positives = 202/451 (44%), Gaps = 36/451 (7%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
YDYD+ VIGGG+ GL A LG KV +++ + LGG C++ GC+P K +
Sbjct: 5 YDYDIIVIGGGAAGLTVTAGAAQLGVKVLLVE--------SGHALGGDCLHYGCVPSKTL 56
Query: 78 HQAALLGESIHEAVAYGW---EVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKI 134
+ A + + A YG ++P +D ++ ++E VQ I+ + V R ++
Sbjct: 57 LRTAGVRHLMRHAARYGLPDAQLPPVDFAQVA-QRISE-VQAVIQQHDSVERFTALGAEV 114
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIF 193
+ G F D HT + + S T IVIA G P + G E +++ +IF
Sbjct: 115 LF--GAASFADDHT-VEIRSDDSVVRATGAKIVIATGSGASVPPLEGLKESGYLTNREIF 171
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQK 252
SL P +V+G G + LE A LG TV+ RS L D MA V +E +
Sbjct: 172 SLPVLPASLIVLGGGPVALEMAQAFRRLGTEVTVVQRSGQLLSNEDADMADIVRLRLESE 231
Query: 253 GVVFHNKCVPLSVEKLETG-QLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
GV + S+ + G Q++ + +E + +L+A GR L LE A
Sbjct: 232 GVRVLTRTEIQSIRRGADGVQVRLVHEGSEKLLSAAE----LLVALGRAPHVSGLTLENA 287
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
GV S G + +TNV +IYA GDV G+ T A + G ++ + D
Sbjct: 288 GVV-YSARGVGVDARMRTNVPHIYAAGDV-TGRYLFTHAAGYEGGIIIANAVFRLPKKAD 345
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGAD---KVEVYHAFYKPTEFFIPQRNIRNCYL 428
Y N+ FT E VGL+E A A G D + E++ + P+ I+
Sbjct: 346 YTNMPWCTFTDPELASVGLNERRAQAA-GVDYTVRTELFSGNDRALAEGAPEGRIK---- 400
Query: 429 KAVALREAPQRILGLHFVGPVAGEVIQGFAA 459
L + +++LG+ G AGE+I + A
Sbjct: 401 ---MLLDPREKVLGVQICGAGAGEIINQWVA 428
>UniRef50_A3H831 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Thermoproteaceae|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Caldivirga
maquilingensis IC-167
Length = 490
Score = 133 bits (321), Expect = 1e-29
Identities = 125/454 (27%), Positives = 210/454 (46%), Gaps = 37/454 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ VIGGG GG A E G V ++D K LGG C+ GCIP K +
Sbjct: 30 YDVVVIGGGGGGYHGAFELSKGGYSVLLVD--------DKGNLGGNCLYEGCIPSKAVSV 81
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKIN--WPALTEAVQNHIKSVNWVTRV-DLREK-KID 135
+ L E + ++ V + DA K+ W L + N ++ + ++ + +++E +D
Sbjct: 82 SLYLLEKLRGILS---SVGNNDAEKVRLLWENLIDHKDN-VQYLRYLQHIREIKEHGNVD 137
Query: 136 YVNGLGEFKDAHTLIATLKNGS-KKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFS 194
+V G+ D H +I +GS ++E+ + +++A G P +PGA + + S ++F
Sbjct: 138 FVKGIARVIDNHRVIVESIDGSWRREVEGRYLLVATGSLPIKIPVPGA-DLTLGSQELFG 196
Query: 195 ----LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSE 248
L P +V+G GYIG+E A L+ LG T+ V +P L G+D + + +
Sbjct: 197 YRTKLRRIPSDVVVIGGGYIGVEVASVLSGLGVKTTI-VEMLPRILSGWDSGIVSMIEEK 255
Query: 249 MEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNL 308
+ +GV + K E GQ + + G V+MA GR A + +L
Sbjct: 256 LRSRGVAILTNSRVTGI-KEEGGQKIVEYSRPDGSV-GYVTGSEVIMAVGRRANVE--DL 311
Query: 309 EAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG-AT 367
G+ V + + T V N+YA GDV+ G+ L A+ + + + G
Sbjct: 312 SQLGI--VDRNHVDVNSAMATKVPNVYAAGDVI-GRYMLYHAAVKESVVASWNIMMGRQI 368
Query: 368 QPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCY 427
++++ + T+FT E VGLSEE A AR G + V + + + +R+ +
Sbjct: 369 FEVNFNTIPMTIFTEPEAAMVGLSEEAAKAR-GINYTVVQYPL--SDDSYAQIIGVRDGW 425
Query: 428 LKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+K + +E QRI+G G A +I A A+
Sbjct: 426 VKLIIEKET-QRIIGGVIYGEAASMMINEVALAI 458
>UniRef50_Q8DTC8 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Streptococcus|Rep: Dihydrolipoyl dehydrogenase -
Streptococcus mutans
Length = 445
Score = 132 bits (320), Expect = 1e-29
Identities = 112/382 (29%), Positives = 175/382 (45%), Gaps = 40/382 (10%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK--LM 77
YDL +IG G GG A+EA LG KV V++ K +GGTC+NVGCIP K L
Sbjct: 4 YDLLIIGAGPGGYIAAEEAARLGKKVAVVE---------KKDIGGTCLNVGCIPSKAYLQ 54
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
H LL S+ EA YG S + +++ L + ++ + KIDY
Sbjct: 55 HSHWLL--SMQEANKYG---ISTNLESVDFAKLVNRKDQVVSTLQGGIHTTFKSLKIDYY 109
Query: 138 NGLGEF-KDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIFS 194
G +F KD ++ NG K I+ K++++A G P P I G +V Y +++D F+
Sbjct: 110 EGQAQFLKDKSFMV----NGEK--ISGKDVILATGSHPFIPQIHGINSVNY-LTTDSFFN 162
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGV 254
L P K +++G G I +E A + LG TV+ + Q + +E +
Sbjct: 163 LKVLPEKLVIIGGGVIAIELAFAMQPLGVNVTVI----------EIAPQILLTEDKAARA 212
Query: 255 VFHNKCVPLSVEKLETGQL-KARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ K + E ++ + Q+ + G FD +L+ATGR T+ + G+
Sbjct: 213 IIRKKLKTMGAHIFEAAKIEEVHAQSVILEGDGAQEFDQLLVATGRKPNTEL--AQEMGL 270
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ + +T+ ++YA+GD+ E L VA G R + A P+D
Sbjct: 271 KLTERGFVKVDDYYETSTPHVYAIGDLTESY-MLAHVASMEGIKAVRAICRQAQDPVDAQ 329
Query: 374 NVATTVFTPLEYGCVGLSEETA 395
V +++T E GLSEE A
Sbjct: 330 GVPRSLYTNPEVASFGLSEEEA 351
>UniRef50_Q4L6L9 Cluster: Dihydrolipoyl dehydrogenase; n=16;
Staphylococcus|Rep: Dihydrolipoyl dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 474
Score = 132 bits (320), Expect = 1e-29
Identities = 108/445 (24%), Positives = 198/445 (44%), Gaps = 30/445 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL ++GGG+ G A A LG KV +++ K LGGTC++ GCIP K + +
Sbjct: 6 YDLVILGGGTAGYVAAIRASQLGNKVAIVE---------KSLLGGTCLHKGCIPTKALLK 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A + ++ ++V +G V + ++ + + ++ +++ ID NG
Sbjct: 57 SAEVLRTVKDSVHFGVNVGQYS---FDLKSMMKRKDKIVNQMHQGIESLMQKNHIDIFNG 113
Query: 140 LGEFK-------DAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDD 191
G + T+ N + + +N++IA G P P +P +SS+D
Sbjct: 114 TGRIMGTSIFSPQSGTISVEYDNVESELLPNQNVLIATGSLPTQLPFLPFNHNTVLSSND 173
Query: 192 IFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEME 250
I L P ++G G IGLE A L LG +V+ L Q+A + + +
Sbjct: 174 ILQLTDLPASIAIIGGGVIGLEFASLLIDLGVNVSVIEAGERILPNESAQIANFLKTSLI 233
Query: 251 QKGVVFHNKC-VPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
+GV F+ C + S K+ + + + +T E + VL++ GR T + L
Sbjct: 234 ARGVTFYENCALNESAVKVNSNSVTIQVNKDKTIE-----VEKVLVSIGRKPNTDDIGLN 288
Query: 310 AAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
+ N ++ + QT +IYA GD + GK +L V+ L MF G P
Sbjct: 289 NTKIKTDDNGNILVNDFLQTEDKHIYAAGDCI-GKLQLAHVSSKEAILAVEHMFNGNGLP 347
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
++YD + ++T E +G ++E+A A++ K + + + + + +
Sbjct: 348 LNYDKMPKCIYTHPEVASIGYNKESAEAKN--IKTKSFKVSFNAIGKAVIEETTNDRGFC 405
Query: 430 AVALREAPQRILGLHFVGPVAGEVI 454
+ + + I+G++ +GP E+I
Sbjct: 406 EMIINDETNEIIGINMIGPQVTELI 430
>UniRef50_A6C4P3 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Dihydrolipoyl
dehydrogenase - Planctomyces maris DSM 8797
Length = 475
Score = 132 bits (320), Expect = 1e-29
Identities = 130/453 (28%), Positives = 200/453 (44%), Gaps = 28/453 (6%)
Query: 15 AGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVL-DYVTPSPQGTKWGLGGTCVNVGCIP 73
+ T + D+ VIGGG GG A EA + G KV ++ D V P GG C+N GCIP
Sbjct: 4 SATRETDIVVIGGGPGGYPAAFEAADKGYKVIMVNDDVAP---------GGVCLNRGCIP 54
Query: 74 KK-LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREK 132
K L+H A L+ E+ A W + + +IN L + + + +
Sbjct: 55 SKALLHVAKLINETRESAE---WGI-TFQKPEINLDQLRDFKNKVVTQLTGGIGQLAGAR 110
Query: 133 KIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSDD 191
++ + G G FKDA+++ T ++G+ + I K ++A G P P + + + S
Sbjct: 111 NVEILKGFGRFKDANSVEVTKQDGTTETIQFKYAIVATGSSPAVPPVFDLDDDRIMDSTG 170
Query: 192 IFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEME 250
L P K LVVG GYIGLE +LG TV+ + L G D+ + + + +
Sbjct: 171 ALELADIPTKLLVVGGGYIGLEMGSVYAALGSEVTVVEMTGGLLPGADRDLVRPLQKRLT 230
Query: 251 QKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
+ H + VEKL G + + VFD VL++ GR K + E
Sbjct: 231 ESFAAIH---LNTKVEKLTPGDNGITADLSGEGVEPQQVFDRVLISIGRRPNKKGIGFEN 287
Query: 311 AGVTCVSNSGKIIAETEQ-TNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
+ + G I + +Q T +IYA+GD+ G+P L A + +A AG
Sbjct: 288 TKLE-LDERGFIKHDAQQRTAEPHIYAIGDI-AGEPMLAHKATREAK-VAIESIAGEFGE 344
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
D + VFT E G++E+ A G D VE+ + + Q R L
Sbjct: 345 FDNIAIPAVVFTDPELAWCGVTEQEA-KDQGLD-VEITRFPWAASG--RAQTLGRTEGLT 400
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + R+LG+ VGP AGE+I AV+
Sbjct: 401 KMIFDKKTGRVLGVGIVGPGAGELIAEGVMAVE 433
>UniRef50_Q0W7Q8 Cluster: Dihydrolipoamide dehydrogenase; n=2;
Euryarchaeota|Rep: Dihydrolipoamide dehydrogenase -
Uncultured methanogenic archaeon RC-I
Length = 456
Score = 132 bits (320), Expect = 1e-29
Identities = 130/444 (29%), Positives = 203/444 (45%), Gaps = 33/444 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL VIG G+G A++ G+KV + D + GGTC+N GCIP K++
Sbjct: 4 FDLIVIGSGAGD-QIVSYALSDGSKVALAD---------RGPTGGTCLNTGCIPSKMLIY 53
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLRE-KKIDYVN 138
A + + EA A G IK ++ + E ++N + LR+ K + +
Sbjct: 54 PADVIRAAQEASAIG----VATTIKPDFGQIMERMRNFVDGERQGMEEGLRKAKNLAFYQ 109
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLGH 197
G+ EF H TLK GS EITA IVIA G R P IPG E + + + L
Sbjct: 110 GVAEFTGPH----TLKVGS-HEITAPKIVIATGARVAIPPIPGLKETGYLDNVSLLQLRE 164
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGVVF 256
P +++G GYIG E A F +++G T++ R V L D +++ VT M + +
Sbjct: 165 MPKSLIIIGGGYIGCEYAHFFSAMGADVTIVSRPPVLLNDEDPEVSDTVTKVMSR----Y 220
Query: 257 HNKCVPLSVEKL-ETGQLKARWQNTETQ-ERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
+ +K+ G K + ++ D +L+A GR + L E AGV
Sbjct: 221 VHVQTGFEADKVGREGDRKVVYAKSKKDGTTASFEADEILVALGRRSNADLLKPEKAGVE 280
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ + + +T+V I+A+GD + G+ A + ++ MF+ +D
Sbjct: 281 TDAKGWIKVNKYLETSVPGIWAIGDAI-GRYMFRHTANYHAEVVYTNMFSEHKMEVDEHA 339
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V VFT + G VG++E A A+ KV V A Y T I N + ++K V
Sbjct: 340 VPHAVFTHPQVGHVGMTE--ADAKAAGIKVLVGRAKYIQTAKGIAMHN-HDGFVKVVVTA 396
Query: 435 EAPQRILGLHFVGPVAGEVIQGFA 458
+ ++ILG VGP A ++Q A
Sbjct: 397 D-NKKILGCSVVGPDAAVLVQQVA 419
>UniRef50_Q3XWK1 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation
region; n=1; Enterococcus faecium DO|Rep: FAD-dependent
pyridine nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Enterococcus faecium DO
Length = 440
Score = 132 bits (319), Expect = 2e-29
Identities = 107/379 (28%), Positives = 175/379 (46%), Gaps = 31/379 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD +IG G GL+ A G V V++ WG GTC N GC PKK++
Sbjct: 4 YDAIIIGSGVSGLSAAYGLKEAGKTVLVVEE-------DLWG--GTCPNRGCDPKKVLLS 54
Query: 80 AALLGESIHEAVAYGW-EVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A + + G+ E+P+ NW L + + V + L E +ID+++
Sbjct: 55 AVEARNRVKQLSGKGFNEIPTA-----NWEELQKFKRTFTDPVPESRKKQLAEAEIDHLS 109
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
G F D ++ +++ A +V+A G RP + G EY +S D SL
Sbjct: 110 GTARFLDDSSIEV-----NEEVFHADYLVLATGQRPTILPVEGK-EYLKTSADFLSLPVL 163
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFH 257
P + + +G GYI E A N+ G T++ + PL+ F+ + + +ME G+ F
Sbjct: 164 PKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEASGIQF- 222
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ +K+ + + R ET E V D + ATGR T++L LE A +
Sbjct: 223 --AFGVETQKIISEGTRYRLVGKET----ELVADMIFCATGRQPNTESLALEQANIV-FD 275
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGK-PELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
G + + QT+ I+A GD++ K P+LTPVA G +A+R+ ++P+ Y +
Sbjct: 276 KHGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPIIP 335
Query: 377 TTVFTPLEYGCVGLSEETA 395
T V+ + VG+++ A
Sbjct: 336 TIVYASPKLAEVGVTKSHA 354
>UniRef50_Q1IIJ6 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 471
Score = 132 bits (319), Expect = 2e-29
Identities = 118/444 (26%), Positives = 203/444 (45%), Gaps = 31/444 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ +IG G G A A G K +++ + K LGGTC++VGCIP K +
Sbjct: 6 YDVVIIGSGPAGYTAAIRAGQFGLKTALIE------KDAK--LGGTCLHVGCIPTKSLLF 57
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + + I EA +G E L K+NW + E Q I + +++ K+ + G
Sbjct: 58 NAEIYDHIKEAEEFGIE--GLGTPKLNWSKVQERKQAIIDKHAKGLQFLMKKNKVTVIPG 115
Query: 140 LGEF----KDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIF 193
G K + +G K+ + AKN++++ G +PG A + +++ +I
Sbjct: 116 FGRLTGPAKGGIHSVEVEADGKKQNVQAKNVLLSTGSVARM--LPGLQADDRILTNIEIL 173
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEME 250
SL P +V+G+G +G+E A S G T+ L R VP+ D+++++ + +
Sbjct: 174 SLKEIPKSLVVIGSGAVGVEFASIYKSFGTDCTIIEMLPRLVPVE--DEEVSKELLRNYK 231
Query: 251 QKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
++G+ H EK +TG +K + QE E + L+A GR T+ + +E
Sbjct: 232 KRGINCHVNAKTDKFEKTKTG-VKVTFTVDGKQESIEA--EKCLVAIGRAPRTEGVGIEK 288
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
+ + + E QT +YA+GD++ G +L G + + T+P+
Sbjct: 289 TNIK-LERGFVPVNEWMQTTEPGVYAIGDIVLGLQQLAHAGAMEGMVAVAHIAGKPTKPV 347
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
D V + E G VGL+E A A+ +V++ F N ++K
Sbjct: 348 RKDRVPGATYCHPEIGSVGLTE--AQAKEAGHEVKI-GKFPFTANSRASIVNQHEGFVKV 404
Query: 431 VALREAPQRILGLHFVGPVAGEVI 454
VA + + ILG+H +GP A E++
Sbjct: 405 VADAKHGE-ILGVHIIGPQATELV 427
>UniRef50_A1HU83 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Dihydrolipoyl
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 466
Score = 132 bits (319), Expect = 2e-29
Identities = 137/447 (30%), Positives = 204/447 (45%), Gaps = 34/447 (7%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP-KKLMHQA 80
+ +IGGG GG A A LGA+V +++ LGGTC+NVGCIP K L+H A
Sbjct: 5 IVIIGGGPGGYVAAIRAAQLGAEVHLVEADR---------LGGTCLNVGCIPTKSLLHTA 55
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
L E + + G + D ++++WP L Q + + L+ K+ G
Sbjct: 56 QLYRE-VQKGGLIGLKA---DNVRVDWPVLQSRKQATVTRLVKGVESLLKANKVTVHKGQ 111
Query: 141 GEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSDDIFSLGHPP 199
KDA T+I + ++KE+ A IV+A G P + PGA + I S SL P
Sbjct: 112 AALKDARTVI--VSGETEKEVAADIIVLATGSEPVKLNFPGAELPGVIDSTAALSLPSVP 169
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKGVVFH 257
++VG G +G+E A ++LG TV V +P L D ++A V E+ ++GV F
Sbjct: 170 TSLVIVGGGVVGIEFAALYSALGARVTV-VELLPEILPPVDGEIAVKVRQELTRQGVTFL 228
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVF-DTVLMATGRYALTKTLNLEAAGVTCV 316
L+ + G L A E + E+V + VL+A GR T+ L LEA GV
Sbjct: 229 TG-ARLTEVRQGDGALTAL---VEAGGKVEEVTGEYVLVAVGRRPRTQGLGLEAVGVAL- 283
Query: 317 SNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
+ G+I + E T V IYAVGD G+ L A G + A G +
Sbjct: 284 -DRGRITVDEHFVTTVPGIYAVGD-CNGQIMLAHAASAQG-IAAVEHALGHQAAYYPQTI 340
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
+ ++ E VGL+EE A + A K ++ + + + L V E
Sbjct: 341 PSCIYIQPEVAGVGLTEEEAKKQGIAYKTGLFP--LSASGKAVIDGGMSG--LVKVIAGE 396
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
ILG+H GP A ++I A A++
Sbjct: 397 KYGEILGVHIFGPRATDLIGEAALAIR 423
>UniRef50_Q9KES0 Cluster: Dihydrolipoyl dehydrogenase; n=1; Bacillus
halodurans|Rep: Dihydrolipoyl dehydrogenase - Bacillus
halodurans
Length = 462
Score = 132 bits (318), Expect = 2e-29
Identities = 114/391 (29%), Positives = 184/391 (47%), Gaps = 29/391 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
YD+ VIGGG GG A +A LG KV +++ LGGTC+N GCIP K L+H
Sbjct: 4 YDIVVIGGGPGGYVAAIKAAKLGKKVALVE---------AKDLGGTCLNRGCIPSKTLLH 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
Q ++ E I +A +G E A+ ++ P + I+ + L++ KID
Sbjct: 55 QGEII-EKIKQAKEWGIET---GAVTLSLPKMLARKNEIIQKLRAGIHFLLKQGKIDVYF 110
Query: 139 GLGEF-KDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCI-SSDDIFSLG 196
G GE +D I + + +N+++A G P P +PG E + +SD IF L
Sbjct: 111 GYGEIERDRSVKIKMKETAEIVSVRTENMIVATGTEPTIPPVPGLAEAVVDTSDTIFELD 170
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVV 255
P +++G G IG+E A +SL T++ + L D++ A+ + + KGV
Sbjct: 171 SIPQSIVIIGGGVIGVEIACIFSSLQVDVTIVEMGKRILPQEDEEAAKVLAKALAAKGVH 230
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
+V L+ + K + T T +R + +L+A GR T NL
Sbjct: 231 LLTNTKVTAV--LQGDKQKVEIE-TSTGDRDWLEGERILLAVGR-----TPNLSVVKELG 282
Query: 316 VSNSGKIIAETEQTNVS--NIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ +G + +Q S +IYA+GDV+ G +L VA G L+A +G + ++
Sbjct: 283 LGMAGPFLKVDDQMRTSDPSIYAIGDVIGGW-QLAHVASAEG-LVAAANASGKVEIINRQ 340
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKV 404
+ ++T E VGL+E+ A + + KV
Sbjct: 341 VIPRCIYTQPEIASVGLTEQEAKEKGYSYKV 371
>UniRef50_Q8Y768 Cluster: Lmo1433 protein; n=12; Listeria|Rep:
Lmo1433 protein - Listeria monocytogenes
Length = 446
Score = 132 bits (318), Expect = 2e-29
Identities = 126/449 (28%), Positives = 202/449 (44%), Gaps = 36/449 (8%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+ YD+ +IG G+ G A EA G KV +++ WG GTCV GC PKK++
Sbjct: 4 FTYDVVIIGSGASGTTVAFEAQAAGLKVAIVEE-------RNWG--GTCVLRGCDPKKVL 54
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
A G + A I+W L + +++V +E I+
Sbjct: 55 IGAREARNLSTRLRGKGIK----QAATISWTDLMAFKETFVENVPESRLASFQEAGIETF 110
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
G F+D+H+L I A+ IVIA G P + G EY +SDD SL
Sbjct: 111 FGAASFQDSHSLQV-----GDDLIYAEKIVIATGATPSTLKVEGK-EYIQTSDDFLSLEK 164
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGVVF 256
P + +G GYI E A + G ++ S PL+ FD A+ + ++ +G+ F
Sbjct: 165 LPDSVVFIGGGYISFEFASIALAAGRDVHIIHHNSEPLKKFDPDFVAALVANIKDEGIHF 224
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
H +E + G+L + +++ + + D ++ ATGR L+LE A +
Sbjct: 225 HFDTDITKIEN-DGGKLHIKGKDSFSLQT-----DLIIGATGRMPNIAHLSLENASID-Y 277
Query: 317 SNSGKIIAETEQT-NVSNIYAVGDVLEGK-PELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ G ++ E QT N +IYA GDV K LTPV L+A+ + G + + Y
Sbjct: 278 TKKGIVVNEKLQTPNNPHIYACGDVAATKGAPLTPVVSLEAALVAKNVI-GVNEKITYPA 336
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQR-NIRNCYLKAVAL 433
+ + VFT + +G+S E A A +K ++ + + T ++ +R N + K +
Sbjct: 337 IPSVVFTSPKLASIGISTEEAKA--NPEKYQIKN--HDTTSWYTYKRTNEQIALAKIIED 392
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
RE+ Q I G HF+ A +I A +K
Sbjct: 393 RESGQ-IKGAHFLSEEADYMINYIAILMK 420
>UniRef50_Q1JWV4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Desulfuromonas
acetoxidans DSM 684|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Desulfuromonas
acetoxidans DSM 684
Length = 459
Score = 132 bits (318), Expect = 2e-29
Identities = 125/438 (28%), Positives = 198/438 (45%), Gaps = 27/438 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+ VIG G GG A A G K +++ + GGTC+N GCIP K++
Sbjct: 4 FDVIVIGSG-GGTKIALPAAQRGLKTALIE---------RDAFGGTCLNRGCIPSKMLIY 53
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLRE-KKIDYVN 138
A + +I A V + I ++ AL + V + ++ +R+ +DY+N
Sbjct: 54 PADMIYAIRNARRVN--VYADQQIDGDFSALVQRVTKTVSQMSEHFADKVRQLDHLDYIN 111
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLGH 197
G G F A ++ NG +++TA I IA G RP P+IPG + ++S +
Sbjct: 112 GSGHFV-ADKVVEV--NG--RQLTAPTIFIATGARPSIPEIPGLADTPYMTSTEALRCES 166
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P + +++GA YI E + G LVRS LR D + A + Q+ + H
Sbjct: 167 LPKRMVIIGASYIACELGHVYEAFGTETHFLVRSALLRQEDDDIRTAFADDFRQRHTL-H 225
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
P+ V + E R ++ E E + +L++TG +T L LE +TC
Sbjct: 226 MGFEPVEV-RWEDELFCIRLRHNEKGTEKELYAEALLVSTGVDPVTDDLGLEHTAITCND 284
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMF-AGATQPMDYDNVA 376
+ + QT V +YA+GD + G G L R +F A + +P+ Y V
Sbjct: 285 KGFIEVDDHLQTAVPGVYALGDCV-GNYLFRHSVNFEGEYLMRTLFEAPSDEPIVYGAVP 343
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
VFT E VG E+ L + G D V V A Y + + R + N + K + R +
Sbjct: 344 RAVFTVPEMAAVGAGEK-QLQQQGVDYV-VGRADYADSNMGM-ARMLENGFAKLLFDRNS 400
Query: 437 PQRILGLHFVGPVAGEVI 454
+R+LG H +G A ++I
Sbjct: 401 -RRLLGAHIIGEEASDLI 417
>UniRef50_Q11PG6 Cluster: Pyridine nucleotide-disulphide-related
oxidoreductase; n=1; Cytophaga hutchinsonii ATCC
33406|Rep: Pyridine nucleotide-disulphide-related
oxidoreductase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 496
Score = 132 bits (318), Expect = 2e-29
Identities = 119/452 (26%), Positives = 213/452 (47%), Gaps = 31/452 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ +IG G G A A A++L V +++ K +GG + G I K +
Sbjct: 3 YDVCIIGAGPAGYAAAMRALDLNKSVILIE---------KDKIGGAGLYNGAISSKTFWE 53
Query: 80 AALLGESIHEAVA-YGWEVPSLDAIKINWPALTEAVQN---HIKSVNWVTRVDLREKKID 135
A ++ + +A Y + + + E + N H++ + + +
Sbjct: 54 LAKDIQTARKRLAQYSPDQHFSVTYQQVLRQVREGIANRRFHLEG-QIESLAKQQTSRFR 112
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEIT-AKNIVIAVGGRPH-YPDIPGAVEYCISSDDIF 193
Y+ G + +T+ + G+++EI A+N+VIA G +P P+IP + ++SD +
Sbjct: 113 YIKGSAKLVSHNTV--EVSTGTEEEIIEAENVVIATGSKPRKLPNIPIDEKIIVTSDGVE 170
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV----RSVPLRGFDQQMAQAVTSEM 249
+ + P +++GAG IG E A ++ GY + ++ R +P D + V + M
Sbjct: 171 NFENFPKSLVILGAGVIGCEWATIFSNFGYTSVNIIDKAERILPFE--DDDVTDVVEANM 228
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
+++G+ H K LS+ ++ G+++ + T+ ++ V + VL++ GR T+ L LE
Sbjct: 229 KKQGITVHKKSNLLSM-RIVDGEVEYILEYTDGRKEMHRV-EKVLVSVGRIPNTQNLGLE 286
Query: 310 AAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
GV ++N G+I QTN+ NIY GD+ L VA GR + +MF +
Sbjct: 287 RVGVNILAN-GQIENTDGQTNIPNIYVAGDI-SSDVALVNVAELEGRHVIEKMFGLSDSV 344
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
+ Y+NV+T +F E VG++E+ AL + KV Y I RN + + K
Sbjct: 345 ITYNNVSTIMFVQPEVAGVGMNEKKALQNKMSYKVVKIR--YDMIPRAIAMRN-NDGFFK 401
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ +A +I+G+ VG A IQ A +
Sbjct: 402 ILVTNDADMKIIGMRAVGVHASSAIQAVALLI 433
>UniRef50_Q047B7 Cluster: Glutathione reductase; n=4;
Lactobacillus|Rep: Glutathione reductase - Lactobacillus
gasseri (strain ATCC 33323 / DSM 20243)
Length = 443
Score = 132 bits (318), Expect = 2e-29
Identities = 108/337 (32%), Positives = 161/337 (47%), Gaps = 26/337 (7%)
Query: 63 GGTCVNVGCIPKKLMH---QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIK 119
GGTC NVGC PK + QAALL + ++G E A INW L + +
Sbjct: 38 GGTCPNVGCEPKIYLDGAVQAALLSRQLE---SHGIE----QAATINWSQLMKEKKERFA 90
Query: 120 SVNWVTRVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDI 179
S TR ++ K D V+G F D T+ +++ I+IA G RPH I
Sbjct: 91 SWPSETRKNI-SKICDVVSGSAHFIDQQTIAV-----NQRYFQGNKIIIATGRRPHELSI 144
Query: 180 PGAVEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFD 238
PGA ++ S D+ SL +GAGY+ +E A FL + G T+LVR LR F
Sbjct: 145 PGA-KFLHDSSDVLSLNKVSEHVTFIGAGYVAMELATFLAAAGSQVTILVRGKHVLRHFY 203
Query: 239 QQMAQAVTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATG 298
Q+ + + + M Q+G+ F + E QL ++ E + V D V+ A+G
Sbjct: 204 QKYSAELVTRMVQRGIQF-----KFATEATCITQLSDKYV-VELNQGSSLVTDYVVNASG 257
Query: 299 RYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVL-EGKPELTPVAIHAGRL 357
R + + L+L AA + S G + + QT+V NIYA+GDV + P LT VA
Sbjct: 258 RTSNIEKLDLSAAQID-YSPKGINVDQHLQTSVKNIYAIGDVTSQDVPNLTTVAEFQSHY 316
Query: 358 LARRMFAGATQPMDYDNVATTVFTPLEYGCVGLSEET 394
L + G +QP++Y + T VF + G++ ++
Sbjct: 317 LFNSLEKGLSQPINYPAIGTGVFAFPQLAQAGINPDS 353
>UniRef50_A7HBV5 Cluster: Dihydrolipoamide dehydrogenase; n=2;
Anaeromyxobacter|Rep: Dihydrolipoamide dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 481
Score = 132 bits (318), Expect = 2e-29
Identities = 139/447 (31%), Positives = 201/447 (44%), Gaps = 39/447 (8%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T +D VIG G GG A LG KV +++ T LGG C+N GCIP K
Sbjct: 3 TKTFDAVVIGAGVGGYPAAIRLAQLGKKVALVEKET---------LGGVCLNWGCIPSKA 53
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREK--KI 134
+ AA L + I A G + S + K++ L E +K + + V L EK +
Sbjct: 54 LIAAANLVDEIKGAAERG--IVSGEP-KVDVAKLREFKNGVVKKL--TSGVGLLEKGNGV 108
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAV---EYCISSDD 191
+ V G F A T I +NG + I A+ ++A GGRP +IPG + S+ +
Sbjct: 109 EVVKGTATFVSA-TAIDVEQNGERTRIEAQAFIVATGGRP--VEIPGFAFDGKDVWSAKE 165
Query: 192 IFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEM 249
L P + + +G G IG+E LG T L ++P L G D + + V +
Sbjct: 166 AVDLPEVPKRLVCIGGGIIGMELGTVYAKLGAQVTFL-EALPQILTGVDPEAVRFVQKNL 224
Query: 250 EQKGVVFHNKCVPLSVEKLETGQL--KARWQNTETQERGEDVFDTVLMATGRYALTKTLN 307
Q+GV H EK + G L KA ET D +L+A G + L
Sbjct: 225 RQRGVTVHVNAKAKGFEK-KGGALAVKAEVDGKETTIE----CDKILVAVGFRPSPEGLG 279
Query: 308 LEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT 367
LE GV ++ G + +T+V +++A+GDV G P L A G +A + AG
Sbjct: 280 LEKIGVK-IAPKGIEVDAQYRTSVPSVFAIGDV-TGGPFLAHKASKEGE-IAAEVIAGMK 336
Query: 368 QPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCY 427
D+ + +FT E G VGLSEE A A G D + AF + +
Sbjct: 337 SARDWVAMPGGIFTDPEIGTVGLSEEEARAL-GHDPITGKFAFGALGRAIAIDHT--DGF 393
Query: 428 LKAVALREAPQRILGLHFVGPVAGEVI 454
+K +A R A + ILG+ VGP A ++I
Sbjct: 394 VKVIADR-ASKLILGVTVVGPEAADLI 419
>UniRef50_Q9YBC8 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Desulfurococcales|Rep: Dihydrolipoyl dehydrogenase -
Aeropyrum pernix
Length = 464
Score = 132 bits (318), Expect = 2e-29
Identities = 128/449 (28%), Positives = 195/449 (43%), Gaps = 39/449 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
+DL V+GGG GG A A G V +++ + LGG C N GCIP K L+H
Sbjct: 4 FDLVVVGGGPGGYPAAVRAAQEGLNVALVEMDS---------LGGECTNYGCIPTKALLH 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A L+ G ++ +++ L E V + +K V+ L+ ++ V
Sbjct: 55 PAGLVASLARLKFVKG-------SVDVDFKGLMEWVDSVVKGVSNGVSTLLKGYGVEVVK 107
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGH 197
G + + ++ +GS I +V+A+G P P + E ++ I L
Sbjct: 108 GRAKIRPG--VVEVDGSGS---IGYSKLVLALGTSPASIPGLEPDGEVVHNNRTILGLRR 162
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
PG+ L+VG GYIG+E A + LG T++ + L + ++ V + +GV
Sbjct: 163 KPGRMLIVGGGYIGVEYATAMARLGVEVTIVELLDRLLPNMQRDFSRVVERRLRAEGVKI 222
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
H K K+E + + R+ E G+ +D +L+A GR T + LE GV +
Sbjct: 223 HTK------SKVEAVERRERYAVVEVSGVGKMEYDAILVAVGRRPNTGDVGLEKLGVK-L 275
Query: 317 SNSGKIIAE--TEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+G I + T +T V +YA GDV G P L A + A R ++ D
Sbjct: 276 DKAGYIQVDGATLETGVPGVYASGDV-TGPPLLAHRAFLQAVVAAERAAGDSSAAFDAKA 334
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYK-PTEFFIPQRNIRNCYLKAVAL 433
V V+T E VGL+ E A A G D E P I R C+ K V
Sbjct: 335 VPAVVYTDPELATVGLTLEEARAA-GVDAAETRLPLASLPRVGAI--EGCRECFAKVVYD 391
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
R + + ILG H P A E+I A A++
Sbjct: 392 RSS-RAILGFHVAAPHASEIIAEAALAIE 419
>UniRef50_Q8A2W9 Cluster: Dihydrolipoyl dehydrogenase; n=7;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Bacteroides
thetaiotaomicron
Length = 447
Score = 131 bits (317), Expect = 3e-29
Identities = 115/446 (25%), Positives = 191/446 (42%), Gaps = 30/446 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
Y + +IGGG G A+ A G V +++ K LGG C+N GCIP K +
Sbjct: 3 YQVIIIGGGPAGYTAAEAAGKAGLSVLLIE---------KNNLGGVCLNEGCIPTKTLLY 53
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A +S + Y V + + P + ++ + + L + V G
Sbjct: 54 SAKTYDSARHSSKYAVNVSE---VSFDLPKIIARKSKVVRKLVLGVKAKLTSNNVAMVTG 110
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISSDDIFSLGH 197
+ D +T+ ++ A+N+++ G P I G V Y D + S
Sbjct: 111 EAQIIDKNTVRC-----GEETYNAENLILCTGSETFIPPITGVETVNYWTHRDALDSK-E 164
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P +VG G IG+E A F NSLG TV+ + L G D++++ + +E ++G+ F
Sbjct: 165 LPASLAIVGGGVIGMEFASFFNSLGVQVTVIEMMDEILGGMDKELSALLRAEYAKRGIKF 224
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
+++ + E G + ++N E +G + + +LM+ GR +TK LE +
Sbjct: 225 LLSTKVVALSQTEEGAV-VSYENAE--GKGSVIAEKLLMSVGRRPVTKGFGLENLNLDKT 281
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ E QT++S +Y GD L G L A+ +A G M Y +
Sbjct: 282 GRGAIKVNEKMQTSLSGVYVCGD-LTGFSLLAHTAVREAE-VAVHSILGKEDAMSYRAIP 339
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
V+T E VG +EE+A A+ KV Y F+ + N K L +
Sbjct: 340 GVVYTNPEIAGVGETEESASAKGITYKVVKLPMAYSGR--FVAENEGVNGVCK--VLLDE 395
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
+RI+G H +G A E+I A++
Sbjct: 396 QERIIGAHVLGNPASEIITLAGTAIE 421
>UniRef50_Q6AQZ1 Cluster: Related to mercuric reductase; n=17;
Proteobacteria|Rep: Related to mercuric reductase -
Desulfotalea psychrophila
Length = 716
Score = 131 bits (317), Expect = 3e-29
Identities = 132/456 (28%), Positives = 203/456 (44%), Gaps = 35/456 (7%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+D +L VIG G+ GL A A L AKVT+++ +GG C+N GC+P K +
Sbjct: 234 FDRNLIVIGAGAAGLVSAYIATTLKAKVTLVEAAE---------MGGDCLNYGCVPSKAL 284
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNH--IKSVNWVTRVD-LREKKI 134
++A + I YG LDA+++++ + H I ++ V+ + +
Sbjct: 285 IKSAKVAHHIRNGDKYG-----LDAVELSFSFRRVMARVHRIIATIEPHDSVERYTDLGV 339
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISS--- 189
+ + G D T+ LK+G + +T++ ++IA G P P +PG AV+Y +
Sbjct: 340 EVLCGYARLLDPWTVEVKLKSGETRRLTSRAVIIATGAGPFIPPLPGLDAVDYLTNETLW 399
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSE 248
+ +L P + LV+G G IG E + L LG + R L D A V +
Sbjct: 400 NAFANLDEAPRRLLVLGGGPIGCELSQALARLGSEVWQIQRGARLLPREDADAAAIVEAS 459
Query: 249 MEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNL 308
+ GV L E+ G+ K E QE FD ++ A GR A K L
Sbjct: 460 LGADGVHVLTGHTALRCER--AGEEKYIVVEHEGQEL-RLAFDALICAVGRVARLKGYGL 516
Query: 309 EAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIH-AGRLLARRMFAGAT 367
E G+ + E QT NI+A GDV G + T A H A + +F G
Sbjct: 517 EELGIPV--KRTVLTNEYLQTLYPNIFAAGDV-AGPYQFTHTAAHQAWYAVVNALFGGIK 573
Query: 368 Q-PMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNC 426
+ +DY + T F E VGL+E+ A A G D VEV + I +R
Sbjct: 574 KFKVDYSVIPWTTFVDPEVARVGLNEQEA-AERGVD-VEVTRYDLDDLDRAITD-GVREG 630
Query: 427 YLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
++K + + RILG+ VG AG+++ F A+K
Sbjct: 631 FIKILTVPN-KDRILGVTIVGEHAGDLLAEFVLAMK 665
>UniRef50_A6U5L4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=2;
Sinorhizobium|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor -
Sinorhizobium medicae WSM419
Length = 473
Score = 131 bits (317), Expect = 3e-29
Identities = 127/445 (28%), Positives = 199/445 (44%), Gaps = 34/445 (7%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+ VIGGG+ GL A A G V +++ K +GG C+N GC+P K + A
Sbjct: 8 DICVIGGGAAGLTVAAGAAAFGVPVVLVE---------KGPMGGDCLNHGCVPSKALIAA 58
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD-LREKKIDYVNG 139
+ SI A +G + + + I+ LT +Q+ I + V+ ++ +
Sbjct: 59 SRHAHSIRVAAEFG--IAAAGPV-IDQERLTARIQSVIVGIAPHDSVERFTSLGVEVIKD 115
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLGHP 198
F D T+ A + I A+ VIA G P P IPG E ++++ +FSL
Sbjct: 116 EACFVDNRTIAA-----GDRLIRARRFVIATGSSPAIPPIPGLAETPFLTNETLFSLKRL 170
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFHN 258
P +V+G G +GLE AG LG TV+ ++ L G D ++A V + +GV H
Sbjct: 171 PRHLVVIGGGPVGLEMAGAHRRLGVEVTVVDKTEALSGQDPELAAIVLDGLRAEGVHLHE 230
Query: 259 KCVPLSVEKLETG-QLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ +VE+ E G +L+ N G D +L+A GR + +L L+AAG+
Sbjct: 231 RTAIHAVERTERGIRLRCENGNGPFGIEGSD----LLVAAGRAPVHASLGLDAAGIR--H 284
Query: 318 NSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ +I + +T+ +YA+GD G T A + RL+ +++ V
Sbjct: 285 DPKRIEVGPNLRTSNRRVYAIGDAAGGL--FTHQASYHARLVLQQILFRLPAREKPFIVP 342
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+FT E VGL+EE AR A + Y + + +K V R
Sbjct: 343 RVIFTEPELAHVGLTEER--AREAAPGATILRLDYSANDRSRTD-GLGRGLIKVVVGRRG 399
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAV 461
R+LG G AGE+I +A AV
Sbjct: 400 --RVLGAAIAGSGAGEMINLWAFAV 422
>UniRef50_A4FLD8 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 491
Score = 131 bits (317), Expect = 3e-29
Identities = 128/468 (27%), Positives = 210/468 (44%), Gaps = 47/468 (10%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
++D+ VIGGG GG A A G V V++ K GG C+N GCIP K M
Sbjct: 3 EFDVLVIGGGPGGYVAAIRAAQRGLSVGVVE---------KERTGGVCLNWGCIPTKAML 53
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
++A + E++ A YG + + + +++ A++ +K + L+ + +
Sbjct: 54 RSAEVYETVLHAADYGVQAEN---VSLDYDAVSRRKDGIVKGLTDGVASLLKANGVTVIY 110
Query: 139 GLGEFKDAHTLI------ATLKNGSKK------------EITAKNIVIAVGGRPHYPDIP 180
G F TL + L G K ++ A++++IA G P +P
Sbjct: 111 GHARFTGPTTLDVYAVGESALGAGGPKYAADPTGDQPVEQVKARDVIIATGSVPVQLPLP 170
Query: 181 GA-VEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFD 238
GA + I+SD F L P + V+G +G E A N+ G T++ ++ + D
Sbjct: 171 GADLPGVITSDGAFGLTEVPKRIAVIGGSAVGAEWASLFNTFGAEVTIIEMQPTLVPAED 230
Query: 239 QQMAQAVTSEMEQKGVVFHNKCVPLSVEKLETGQ---LKARWQNTETQERGEDVFDTVLM 295
++ +A+ + G+ +E G+ LK + QE DV VL+
Sbjct: 231 AEIGKALGRSFGKAGINVLTGSTVSKIESAGRGKNAGLKVFVDGPKAQEIDADV---VLV 287
Query: 296 ATGRYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAG 355
GR T L+LE AGV + + E +TNV ++YA+GDV G+ L VA H G
Sbjct: 288 GVGRKPNTAALDLEKAGVATDARGFVPVDEQLRTNVEHVYAIGDV-TGRVLLAHVASHQG 346
Query: 356 RLLARRMFAGATQP-MDYDNVATTVFTPLEYGCVGLSEETAL-ARHGADKVEVYHAFYKP 413
+ A + AG+ MDYD + FT E VGL+E A+ A H + A
Sbjct: 347 -VTAAEVIAGSDHARMDYDVIPAATFTHPEIASVGLTEAQAVEAGHEVVTGKFPFAAIGR 405
Query: 414 TEFFIPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
T+ + + ++K VA ++ + +LG+H +G A ++I A A+
Sbjct: 406 TKTY----GNSDGFMKIVAGKQYGE-VLGVHIIGQSASDLITEGALAI 448
>UniRef50_Q73M80 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Treponema denticola|Rep: Dihydrolipoyl dehydrogenase -
Treponema denticola
Length = 453
Score = 131 bits (316), Expect = 4e-29
Identities = 117/384 (30%), Positives = 180/384 (46%), Gaps = 36/384 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
YDL V+GGG GG A +A G K +++ K LGGTC+N GCIP K L+H
Sbjct: 2 YDLIVLGGGPGGYVAAIKAGRAGLKTALIE---------KNRLGGTCLNKGCIPTKYLLH 52
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A + G + E D IK + V K V + ++ + +D+ N
Sbjct: 53 TAEVFGSFAENDLGLSGENLKYD-IKAIYEKKNAVVD---KLVGGIEKL-IENAGVDFYN 107
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
G G+ ++ NG KE+ KN++IA G P I G +E ++SDDI LG
Sbjct: 108 GEGKITSKSSVSV---NG--KELEFKNLIIATGSSVFAPPIAG-IETAMTSDDI--LGKE 159
Query: 199 P---GKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGV 254
P +++G G IG+E A +LG T++ + L FD+ +A ++++GV
Sbjct: 160 PVDFKSVIIIGGGVIGIEFATVYANLGKEVTIVELEKTILPPFDRDIAMQQAIVLKKRGV 219
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
N + +EK TG + E +E D V++ GR A K + L++AG+
Sbjct: 220 KIINGAMVTKIEK--TG---CTFTLKEKEE--SITADAVIVCIGRIAEIKDIGLDSAGIE 272
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
G I +TNV IYA+GD ++G L A + G L+ + T+ D
Sbjct: 273 -YDKRGIITDACMKTNVEGIYAIGDAVKGNVMLAHNAENQGHLVVENI-VNNTKHEKQDV 330
Query: 375 VATTVFTPLEYGCVGLSEETALAR 398
+ + V++ E VGLSE+ A A+
Sbjct: 331 IPSCVYSTPEIAGVGLSEKEAEAK 354
>UniRef50_Q0AAN2 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=1;
Alkalilimnicola ehrlichei MLHE-1|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
precursor - Alkalilimnicola ehrlichei (strain MLHE-1)
Length = 473
Score = 130 bits (314), Expect = 8e-29
Identities = 126/445 (28%), Positives = 200/445 (44%), Gaps = 31/445 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
DL +IGGG GGL A A LG K ++D G LGG C++ GC+P K + ++
Sbjct: 4 DLIIIGGGVGGLVTASVAGQLGVKTVLID------AGA--NLGGDCLHYGCVPSKTLIRS 55
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD-LREKKIDYVNG 139
A + A +G + L + + A+ + V+ I + D R +D G
Sbjct: 56 AEVAALTRRAGEFGLQA-ELGPVDLG--AVMDRVRQVIDQIQVHDDPDRFRGYGVDVRFG 112
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCI-SSDDIFSLGHP 198
F D T+ +G + + A+ VIA G P P +PG E +++ IF L
Sbjct: 113 HARFLDRDTVSV---DGER--LQARRFVIATGSAPAVPPVPGLAEAGFHTNETIFQLRTL 167
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVFH 257
P + V+G G IG+E A + LG TV+ + L D + A + S ++ +G+ H
Sbjct: 168 PRRLAVMGGGPIGIELAQAFSRLGSQVTVVEMAAQILPRDDAEQAAELRSVLDAEGITVH 227
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+VE++E + R + D +L+A GR L LEAAGV
Sbjct: 228 ---TATTVERVEQSEGITRLACRNGESHWTVTADALLLAAGRKP-NLDLGLEAAGV-AYG 282
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
G + ++++V +IYAVGD P AG ++A +F + +DY V
Sbjct: 283 PRGIRVDRRQRSSVRHIYAVGDCCGPYPFTHMAEYQAGIVIANALFR-IPKKVDYRVVPW 341
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
+T E VGL+E+ A AR+ KVEV ++ + + + K + R
Sbjct: 342 VTYTAPELATVGLTEDEARARN--LKVEVLRFPFREVDRALAEGETAG-QAKLIVRR--- 395
Query: 438 QRILGLHFVGPVAGEVIQGFAAAVK 462
R++G +GP AGE+I A++
Sbjct: 396 GRLVGASVLGPHAGELIHEAVLAIQ 420
>UniRef50_A3XLG1 Cluster: Dihydrolipoamide dehydrogenase; n=3;
Bacteria|Rep: Dihydrolipoamide dehydrogenase -
Leeuwenhoekiella blandensis MED217
Length = 577
Score = 130 bits (313), Expect = 1e-28
Identities = 124/458 (27%), Positives = 201/458 (43%), Gaps = 39/458 (8%)
Query: 16 GTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK 75
G +DL VIGGGS + A +A +LG +++ G +G GTCVNVGC+P K
Sbjct: 107 GKNQFDLIVIGGGSAAFSAAIKAESLGLTTLMVN------GGLDFG--GTCVNVGCVPSK 158
Query: 76 -LMHQAALLGESIHEAVA----YGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLR 130
L+ A + H A G ++ IK + AL A+Q K ++ V+ +
Sbjct: 159 NLIRAAETAYHTTHSNFAGIKPKGADIDFAQIIK-DKKALVAALQQQ-KYMDVVSDFE-- 214
Query: 131 EKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISS 189
+ + G EF + +T+I K TA N+VIA G + P+I G E +++
Sbjct: 215 --NLTMLKGWAEFVNNNTIIVD----GKDTYTATNVVIATGATTNIPNIEGLNEVGYLTN 268
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSE 248
+F L P ++GAGYIGLE A N LG ++ PLR + + + +
Sbjct: 269 VSLFDLEEKPKSLTIMGAGYIGLEMAMAYNRLGVKVRIIEFTDRPLRSQTEDITDVLVEQ 328
Query: 249 MEQKGVVFHNKCVPLSVEKLETGQLK----ARWQNTETQERGEDVFDTVLMATGRYALTK 304
M+ +G+ EK + T+ E+G +++ATG T
Sbjct: 329 MKSEGIEILPNFRAFKFEKEGNDTIIHCNCPDGSTTQIVEKGH-----IVVATGTTPNTS 383
Query: 305 TLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFA 364
L L+ + ++ E +TN+SNIYA GDV P A G F+
Sbjct: 384 KLGLKKIDLKLSERGHIVVNEKMETNISNIYAAGDV-TNTPPFVYTAATEGSTAVNNAFS 442
Query: 365 GATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIR 424
+ Q +DY ++ VFT + G+ E A +R +V + P + ++ R
Sbjct: 443 LSKQSVDYASLPWVVFTDPQIAGAGMDEIEAESRGIPFEVSKLDLTHVPRA--LAAQDTR 500
Query: 425 NCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
++K + E +++G + P GE+IQ + A+K
Sbjct: 501 G-FIKLIRNTET-DKLIGARVIAPEGGELIQQLSMAIK 536
>UniRef50_Q8ZUT2 Cluster: Mercuric reductase; n=4;
Thermoproteaceae|Rep: Mercuric reductase - Pyrobaculum
aerophilum
Length = 467
Score = 130 bits (313), Expect = 1e-28
Identities = 140/466 (30%), Positives = 205/466 (43%), Gaps = 64/466 (13%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ V+GGGS G+A A +A LGAKV V V P LGGTCVNVGC+P K + +
Sbjct: 2 YDVVVLGGGSAGVAAAVKAAQLGAKVAV---VNSGP------LGGTCVNVGCVPSKFLIR 52
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD-----LREKKI 134
AA L Y E P I +A+ H+K V R + L+ +
Sbjct: 53 AAQLKR-------YA-ERPFFKGISAKVEVAFDALLQHMKEVVEELRREKYEEVLKYYDV 104
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE-----YCISS 189
D + G G KDA T+K G ++E+ + I++A G RP P+IPG E ++
Sbjct: 105 DIIEGYGYLKDA----KTVKVG-EREVRGEKIIVATGARPRVPEIPGLKEAMARGMAFTN 159
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEM 249
++ F L H P + +G G I E + L LG V+ RS L+ +++++A E+
Sbjct: 160 EEFFKLDHMPSSIVFIGGGAIAAELSQALARLGIEVAVIYRSSFLK-YEEEIASKFVEEL 218
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNL 308
N+ V L K ++ R + E + G V + + +A GR N+
Sbjct: 219 ------LANEGVRLI--KAAVTAVEIRGREVEVRHSGGSVRAEALFVAAGR-----APNI 265
Query: 309 EAAG--VTCVSNSGKIIAETEQTNVSNIYAVGDV---LEGKPELTPVAIHAGRLLARRMF 363
E G + N G ++ E +T++ +YA GDV LEG L A G + A
Sbjct: 266 EPLGGLLKLGPNGGVLVNERMETSLPGVYAAGDVTGGLEGARFLENAAARQGVVAAVNAM 325
Query: 364 AGATQPMDYDNVATTVFTPLEYGCVGLSEETAL-----ARHGADKVEVYHAFYK--PTEF 416
G + + V VFT VGL EE + R A +E A + T
Sbjct: 326 GGNAK-FNPLAVPRVVFTDPAVASVGLREEDMIKGGIGCRCRAAPIEAVAAGWTKGQTTG 384
Query: 417 FIPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
FI N Y + + +I G V P A E+I FA A++
Sbjct: 385 FIK----INTYPETWKVSVKRGKIAGALVVAPEAEELINVFAMAIQ 426
>UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7;
root|Rep: Dihydrolipoamide dehydrogenase - Mycoplasma
capricolum
Length = 629
Score = 129 bits (312), Expect = 1e-28
Identities = 118/459 (25%), Positives = 207/459 (45%), Gaps = 46/459 (10%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
+D+ V+G G GG A ++ LG K +++ K GG C+NVGCIP K L+
Sbjct: 164 FDVCVVGAGIGGYVTAIKSAQLGLKTLIIE---------KEYYGGVCLNVGCIPTKTLLK 214
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ + + +H+A G + + + + I+W E +K + + L + K+ +
Sbjct: 215 TSHVYHDIVHKAKELGIVLQNTENVVIDWAQALERKNGVVKKLTGGVKYLLDKNKVTQIK 274
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE-----YCISSDDIF 193
G D +T+ KN N+VIA G P++ +PG + I S I
Sbjct: 275 GEAIALDKNTISVNNKN-----YRVNNLVIASGSTPNHLPLPGFDQGRKDGIIIDSTGIL 329
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQ 251
S+ P +V+G G IG+E + SLG TVL + +P L D+ + A+T E++
Sbjct: 330 SVPKIPETLVVIGGGVIGIEFSCLFASLGTKVTVL-QGLPTILEMLDKDIIDAMTKELKN 388
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
+ + SV++ + G + + + +GE V ++V GR T E
Sbjct: 389 RYNI--QVITNASVKEFKDGSVVYQIDGQDQMIKGEYVLESV----GRK--TSLTGFENI 440
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP-- 369
G+ G ++ E ++TN+ +YA+GDV+ GK L A+ + A R+ A +
Sbjct: 441 GLELTPRKGVVVNEYQETNLDGVYAIGDVV-GKSMLAQTAVKGAIVAANRIAKKANKAHA 499
Query: 370 ----MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFF--IPQRNI 423
M+YD V + ++T E +G +E+ + +E Y AF P +
Sbjct: 500 EDIVMNYDKVPSCIYTHPEVSMIGKTEQQLKQ----ENIE-YKAFKFPFSAIGKALADDD 554
Query: 424 RNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ++K + + + ILG H +G A E+I A ++
Sbjct: 555 TSGFVKII-VEPKYKTILGAHIIGNRATEMISEITAVIE 592
>UniRef50_Q7USN6 Cluster: Glutathione reductase; n=1; Pirellula
sp.|Rep: Glutathione reductase - Rhodopirellula baltica
Length = 451
Score = 129 bits (311), Expect = 2e-28
Identities = 119/446 (26%), Positives = 181/446 (40%), Gaps = 29/446 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL V+G G G A + G +V ++D T GG C GC PKK+
Sbjct: 6 FDLVVLGTGPSGGTVATKIAKAGKRVALVDSRT---------FGGVCALRGCNPKKVYVN 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A L + IH ++ S ++KI+W L + V +E I+ +G
Sbjct: 57 AGQLVDQIHRGDG---KLISDASVKIDWKQLHAFKMEFTQPVAEKKEQSFQEDGIETFHG 113
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
+ F T+ G+K +TA +I GGRP GA E+ SD+ L P
Sbjct: 114 VARFVSPDTIDVV---GTK--LTADRFLIGTGGRPRELSFDGA-EHVTRSDEFLELESMP 167
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFHN 258
+ +G GYI +E AG + G TV+ + + L GFD + +T + + G+ F
Sbjct: 168 EHVVFIGGGYISMEFAGVVARAGSRVTVIEMNNQILSGFDPDLVNQLTDSLREHGIRFQM 227
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+ ++K G L+ N E+ V V+ GR L L +
Sbjct: 228 NAEIIGIDKSADGHLQVHLAN----EQSPIVCGLVVHGAGRVPNIDELCLSQGEIEHGEK 283
Query: 319 SGKIIAETEQTNVSNIYAVGDVLE-GKPELTPVAIHAGRLLARRMFAGATQ-PMDYDNVA 376
+ + ++A GD + G P LTPVA R+ A+ +F+ + DY V
Sbjct: 284 GIAVNQFMQNPTNPRVFATGDCADNGMPRLTPVANEDARIAAKNLFSETLERTPDYGQVP 343
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
FT VGLSEE AR D + V + + ++ + +
Sbjct: 344 KVAFTIPSIASVGLSEEA--ARDSNDNLTVLSD--DISSWGSVRKTGPTVAGYKILIDSK 399
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
ILG H +GP A E I FA A+K
Sbjct: 400 TDAILGAHLLGPSAEETISLFALAMK 425
>UniRef50_Q189R5 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Clostridiaceae|Rep: Dihydrolipoyl dehydrogenase -
Clostridium difficile (strain 630)
Length = 461
Score = 129 bits (311), Expect = 2e-28
Identities = 120/444 (27%), Positives = 207/444 (46%), Gaps = 30/444 (6%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQAA 81
+ V+GGG GG A +A LGA VTV++ K +GGTC+N GCIP K + ++
Sbjct: 3 IVVVGGGPGGYVAAIKASMLGADVTVVE---------KRRVGGTCLNAGCIPTKALLASS 53
Query: 82 LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGLG 141
+ ++ EA +G E+ +K N+ A+ E + + ++ ++ VNG G
Sbjct: 54 GVLNTVKEAKDFGIEIDG--TVKPNFTAIMERKNKVVNQLISGIEFLFEKRGVNLVNGFG 111
Query: 142 EFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDI-PGAVEYCISSDDIFSLGHPPG 200
+ D +T+ T +G+ + I A I++A G P P + P + I+SD++ L P
Sbjct: 112 KLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITSDEVLGLEEIPE 171
Query: 201 KTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFHNK 259
L+VG G IG E F +LG T++ + L D+ +A+ + + ++ +
Sbjct: 172 SMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLLRQFKKDKI---KV 228
Query: 260 CVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+ V+ E KA T G+ + L+ GR +E G+
Sbjct: 229 ITGIGVQTCEVVDGKA----VATLSNGKVIEAQYALVCVGRRPNLDNSGVEDIGIE--ME 282
Query: 319 SGKIIA-ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
GK++ E +TNV IYA+GD+++ P L VA G ++A G T+ +DY +
Sbjct: 283 RGKVVVNEHLETNVEGIYAIGDIID-TPFLAHVASKEG-IVAVENALGKTKVVDYRAIPR 340
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
V+T E VG +E+ L G + V ++ + + ++K +A +E
Sbjct: 341 CVYTEPEVAGVGKTEK-QLEAEGVE-YNVGQFDFRGLGKAQAIGHFQG-FVKVIADKET- 396
Query: 438 QRILGLHFVGPVAGEVIQGFAAAV 461
+I+G VGP A +++ + AV
Sbjct: 397 DKIIGAAVVGPHATDLLTELSLAV 420
>UniRef50_Q1KSF4 Cluster: Dihydrolipoyl dehydrogenase; n=25;
cellular organisms|Rep: Dihydrolipoyl dehydrogenase -
Toxoplasma gondii
Length = 519
Score = 128 bits (310), Expect = 2e-28
Identities = 128/451 (28%), Positives = 209/451 (46%), Gaps = 42/451 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ V+GGG GG A +A LG K ++ +GT LGGTC+NVGCIP K +
Sbjct: 50 YDVVVVGGGPGGYVAAIKAAQLGLKTACVE-----KRGT---LGGTCLNVGCIPSKAV-- 99
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+ + + + +D + I+ + + Q + ++ R +DY G
Sbjct: 100 LNISNKYVDARDHFERLGIKIDGLSIDIDKMQKQKQKVVSTLTQGIEHLFRRNGVDYYVG 159
Query: 140 LGEFKDAHTLIATLKNGSKKE-ITAKNIVIAVGGRPHYPDIPGAV-----EYCISSDDIF 193
G+ D++++ T S+K+ + A +I++A G +PG V + ISS
Sbjct: 160 EGKLTDSNSVEVTPNGKSEKQRLDAGHIILATGSEA--SPLPGNVVPIDEKVIISSTGAL 217
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEME 250
+L P + V+G G IGLE +LG TV L R +P D ++A+A EME
Sbjct: 218 ALDKVPKRMAVIGGGVIGLELGSVWRNLGAEVTVVEFLDRLLP--PVDGEVAKAFQKEME 275
Query: 251 QKGVVFH--NKCVPLSV-EKLETGQLK-ARWQNTETQERGEDVFDTVLMATGRYALTKTL 306
+ G+ F K V V E T ++ A+ N E D VL+A GR TK L
Sbjct: 276 KTGIKFQLGTKVVGADVRESSATLHVEPAKGGNPFDMEA-----DVVLVAVGRRPYTKNL 330
Query: 307 NLEAAGVTCVSNSGKIIAETE--QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFA 364
LE G+ G+++ + N NI A+GD++ G P L A G + M A
Sbjct: 331 GLEELGIE-TDRVGRVVVDDRFCVPNYPNIRAIGDLIRG-PMLAHKAEEEG-IACVEMIA 387
Query: 365 GATQ-PMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNI 423
G + ++Y+ + + ++T E VG +EE L +G + F + ++
Sbjct: 388 GVGEGHVNYETIPSVIYTHPEIAGVGKTEE-ELKANGVSYNKGTFPFAANSR--ARANDV 444
Query: 424 RNCYLKAVALREAPQRILGLHFVGPVAGEVI 454
++K +A +++ ++LG +GP AGE+I
Sbjct: 445 ATGFVKVLAHKDS-DKLLGAWIMGPEAGELI 474
>UniRef50_Q67SE4 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Lactobacillales|Rep: Dihydrolipoyl dehydrogenase -
Symbiobacterium thermophilum
Length = 470
Score = 128 bits (309), Expect = 3e-28
Identities = 125/446 (28%), Positives = 196/446 (43%), Gaps = 27/446 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+ VIG G GG A+ A LG VT+++ + LGGTC+N GCIP K +
Sbjct: 9 DVVVIGAGPGGYVAAQRASQLGLDVTLIE---------REELGGTCLNHGCIPSKALISV 59
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNH-IKSVNWVTRVDLREKKIDYVNG 139
L ++ A G V ++++++ E + IK + ++ +++ V G
Sbjct: 60 GDLLYKVNNAAERGLVVKG--SVEVDFAKTQEWKETKVIKRLTSGVASLMKAGQVEVVKG 117
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDI-PGAVEYCISSDDIFSLGHP 198
F D H+L L +G T K+ +IA G P P E + + +
Sbjct: 118 TARFTDPHSLEVELNDGGTAAYTFKHAIIATGSTAVNPSFFPLDGENVVDARGALAFREI 177
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLR-GFDQQMAQAVTSEMEQKGVVFH 257
P + +VVG GYIG+E LG T++ + L G D + + + + GV
Sbjct: 178 PPRFVVVGGGYIGVELGIAYAKLGSKVTIVEATGQLLPGTDPDLVNVLMRRLRRLGVTVM 237
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ L+ G++K Q+ E + E D VL++ GR T+ L+L+ AGV V
Sbjct: 238 LNA--RASGGLQNGKVKV--QDGEGKVH-EIEADKVLVSVGRVPYTEGLHLDKAGVR-VD 291
Query: 318 NSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
G I + E +TNV +IYA+GDV P + A +A AG D+ V
Sbjct: 292 EKGFIPVDEQMRTNVPHIYAIGDVC--SPVMLAHKASAQGRVAAEAIAGRPSAADWQTVP 349
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+FT E VGL+E A + G D V + F + + +K V R++
Sbjct: 350 AVIFTDPEIAYVGLTEAQAREK-GYDPVVSRYNFAAVGRALTMGES--DGMVKLVGDRQS 406
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
+LG VGP E+I A A++
Sbjct: 407 -GLLLGAQMVGPEVSELIGEIALAIE 431
>UniRef50_UPI000023D207 Cluster: hypothetical protein FG05450.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG05450.1 - Gibberella zeae PH-1
Length = 478
Score = 128 bits (308), Expect = 4e-28
Identities = 111/377 (29%), Positives = 163/377 (43%), Gaps = 24/377 (6%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
TY YD +IG G G AK N G K V++ + LGGTCVNVGC P K
Sbjct: 3 TY-YDAIIIGSGQSGNPVAKAFANAGHKTAVIE---------RTALGGTCVNVGCTPTKT 52
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
M + YG + + +I+ + + + ++ N + L +D
Sbjct: 53 MIASGRAAYMARRGKDYGVHAGNGN-FEIDMARVRQRKRAIVEQWNSGSVRGLNAAGVDV 111
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYC--ISSDDI 192
+ G G F L L +G +KE++A I I VG RP PDI G VE + S I
Sbjct: 112 IMGEGSFVGDKKLKVVLNDGGEKEVSADKIFINVGERPLRPDISGLDGVEPARVLDSTSI 171
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQ 251
L P +V+G GYIGLE LG TV+ R+ L D +A+ + ++Q
Sbjct: 172 MELDAVPEHLVVLGGGYIGLEFGQLFRRLGSEVTVIQRAKQLVPHEDPDVAECLYDILQQ 231
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDT-VLMATGRYALTKTLNLEA 310
G+ + SV ++ N +T DV + +L+A GR T LNL
Sbjct: 232 DGLTVYLSSTVNSVSASTDSKMPFT-VNVQTANGQTDVAGSHILLAAGRVPNTDRLNLSE 290
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRL----LARRMFAGA 366
G+ S ++ + QT+ SN+YA+GD G T ++ R+ L + A
Sbjct: 291 VGIKTTSKGHVVVDDKLQTSASNVYALGD-CHGGAAFTHISYDDSRIIRTNLLPKTMAST 349
Query: 367 TQPMDYDNVATT-VFTP 382
T M +T+ V TP
Sbjct: 350 TPAMPTTQSSTSRVLTP 366
>UniRef50_Q5QYX3 Cluster: Mercuric reductase, membrane-associated;
n=35; Bacteria|Rep: Mercuric reductase,
membrane-associated - Idiomarina loihiensis
Length = 730
Score = 127 bits (307), Expect = 5e-28
Identities = 136/470 (28%), Positives = 213/470 (45%), Gaps = 49/470 (10%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
++D +L VIG GS GL A A + AKVT+++ K +GG C+N GC+P K
Sbjct: 235 SFDNNLVVIGAGSAGLVSAYIAATVKAKVTLIE---------KHKMGGDCLNTGCVPSKA 285
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREK-KID 135
+ A L + A + G V + +++ + + V++ IK + V+ K +D
Sbjct: 286 LLHVAELAHNARNASSAGVHV---GEVSVDFKQVMQQVKSVIKDIEPHDSVERYTKLGVD 342
Query: 136 YVNGLGEFKDAHTLIATLKNGSK---KEITAKNIVIAVGGRPHYPDIPG--AVEYCISSD 190
G + T K K IT ++I+IA G +P PD G V+Y ++SD
Sbjct: 343 VEQGDARIVSPWEVEVTSNVEGKSETKRITTRSIIIATGAKPLVPDFEGLDKVDY-LTSD 401
Query: 191 DIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRG-FDQQMAQAVTSEM 249
++ L P + LV+G G IG E + LG T + + L G D + +T +
Sbjct: 402 TLWELDELPKRLLVLGGGPIGCELSQAFQRLGSQVTQVEMAERLMGPEDADTVELLTRRL 461
Query: 250 EQKG--VVFHNKCVPLSVEKLETGQLKARWQNTET-----QERGEDV---FDTVLMATGR 299
+G + ++K + E+ + + + E+ ++ +DV FD VL+A GR
Sbjct: 462 TAEGIDIRLNHKALRFEQHNGESVLIAEQTVDNESVDNQNADQSKDVEIPFDKVLIALGR 521
Query: 300 YALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIH-AGRLL 358
LE GV +N E QTN NIYA GDV G +LT VA H A
Sbjct: 522 QPNITGFGLEELGVQ--TNKTVSTNELLQTNFPNIYACGDV-AGPYQLTHVASHQAWYAS 578
Query: 359 ARRMF-AGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFF 417
+F T DY + +T + VGL+E+ A ADK Y+ TE+
Sbjct: 579 VNALFDPFKTFRADYSVIPWVTYTSPQVANVGLTEQQA---KKADKP------YEVTEYD 629
Query: 418 IPQ--RNIR--NCYLKA-VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
I + R I + Y + V + +LG++ VGP AGE++ + A+K
Sbjct: 630 IGELDRAIADDSAYGRVKVLTKPGKDELLGVNIVGPQAGELLAEYVLAMK 679
>UniRef50_Q1GHN7 Cluster: Dihydrolipoyl dehydrogenase; n=41;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Silicibacter
sp. (strain TM1040)
Length = 464
Score = 127 bits (307), Expect = 5e-28
Identities = 119/440 (27%), Positives = 200/440 (45%), Gaps = 24/440 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ VIG G GG A A LG K V++ + LGG C+N GCIP K + +
Sbjct: 6 YDVIVIGAGPGGYVAAIRASQLGLKTCVVE---------REHLGGICLNWGCIPTKALLR 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
++ + + A +G + + I + A+ + + K ++ + L++ KID + G
Sbjct: 57 SSEVFHLMERAKDFGLKAEN---IGYDLGAVVKRSRGVAKQLSSGVKGLLKKHKIDVIMG 113
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLGHP 198
A +A + +E+T KNI++A G R P + + +
Sbjct: 114 EATLP-AKGKVAVKTDKGSEELTGKNIILATGARARELPGLEADGDLVWTYKHALDPKRM 172
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P K LV+G+G IG+E A F N+LG TV+ V L D+++++ E++G+
Sbjct: 173 PKKLLVIGSGAIGIEFASFYNTLGADTTVVEVMERVLPVEDEEISKFAKKAFEKQGMKIM 232
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
K + +++ +G++ A + E+ E FDTV+ A G + L LE GV +
Sbjct: 233 QKAMVKQLDR-ASGKVTAHIEVGGKVEKHE--FDTVISAVGIVGNVEGLGLEGLGVK-ID 288
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
+ I E +T V +YA+GD+ G P L A H G ++A + P+ +++A
Sbjct: 289 RTHVITDEYCRTGVDGLYAIGDI-AGAPWLAHKASHEGVMVAELIAGKHAHPVKPESIAG 347
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
+ + VG +E A A+ KV+V + I +K V E
Sbjct: 348 CTYCHPQVASVGYTE--AKAKELGYKVKVGRFPFIGNGKAIALGEPEG-LIKTV-FDEKT 403
Query: 438 QRILGLHFVGPVAGEVIQGF 457
+LG H +G E+IQG+
Sbjct: 404 GELLGAHMIGAEVTELIQGY 423
>UniRef50_Q184K0 Cluster: Putative pyridine-nucleotide-disulfide
oxidoreductase; n=2; Clostridium difficile|Rep: Putative
pyridine-nucleotide-disulfide oxidoreductase -
Clostridium difficile (strain 630)
Length = 462
Score = 127 bits (307), Expect = 5e-28
Identities = 105/380 (27%), Positives = 179/380 (47%), Gaps = 23/380 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D +IG G GG A + N G KV +++ + K GGTCVNV CIP K +
Sbjct: 5 FDAIIIGFGKGGKTLAGDLANRGLKVALIE------KSNKM-YGGTCVNVACIPTKSLEN 57
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A S+ W+ + K E + ++ N+ +++ E + G
Sbjct: 58 SA---NSVKTKNINSWDEVQAEYEKAI--DKKETLITKLREANY-NKLNSNEN-VTIFTG 110
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCI--SSDDIFSLGH 197
+G F D T+ +N E+ A NI I G RP P+I G I S+ + +L
Sbjct: 111 MGTFIDEKTVQVKTEN-EIYELVADNIFINTGSRPFIPNIKGIENKNIVYDSESLMNLRT 169
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P K ++GAG+IGLE AG +S G T+L + L D + ++ + + ++ V
Sbjct: 170 LPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEIIKLLAKRNVKI 229
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
N ++ E +L + + + E + +L+ATGR A T+ L LE AG+
Sbjct: 230 VNNANIKEIK--EVSELAIVEYEVDGKSK-ELTSNMILVATGRKANTEGLGLENAGIELN 286
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM-DYDNV 375
++ET +TN +I+A+GD+ G P+ T +++ R++ ++F T+ D N+
Sbjct: 287 ERGFIKVSETLKTNKEHIWAIGDI-NGGPQFTYISLDDYRIVINQLFGDKTRTTNDRKNI 345
Query: 376 ATTVFTPLEYGCVGLSEETA 395
++F + VGL+ + A
Sbjct: 346 PNSIFISPAFSRVGLNVKQA 365
>UniRef50_Q0C555 Cluster: Pyridine nucleotide-disulfide
oxidoreductase; n=2; Hyphomonadaceae|Rep: Pyridine
nucleotide-disulfide oxidoreductase - Hyphomonas
neptunium (strain ATCC 15444)
Length = 477
Score = 127 bits (307), Expect = 5e-28
Identities = 125/449 (27%), Positives = 206/449 (45%), Gaps = 44/449 (9%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T DLAVIG GS GL+ A A LG KV + + K +GG C+N GC+P K
Sbjct: 6 TLKADLAVIGAGSAGLSAAAGAAMLGLKVVLFE---------KHEMGGDCLNFGCVPSKA 56
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIK-SVNWVTRVDLREK--- 132
+ AA + EAV YG +P A+ +NW +AV+ H++ ++ + +D +E+
Sbjct: 57 LISAAKIAHVPEEAVRYGISLP--PAV-VNW----DAVKAHVRGAIETIAPIDSQERFEG 109
Query: 133 -KIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSD 190
+ F+D +TL++ + A+ I+I+ G R P +PG + +++
Sbjct: 110 LGCTVIREAARFEDKNTLVS-----DSVRVKARRIIISTGSRAIIPPVPGLEDVPYFTNE 164
Query: 191 DIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEME 250
IFS P + +++G G IGLE A + LG TV+ L D A+ +
Sbjct: 165 TIFSAPDFPHELIILGGGPIGLELAQAFSRLGSKVTVVEMGRALPRSDAAHAKIAVDAVR 224
Query: 251 QKGVVF--HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNL 308
+GV +K +S +KA + G +L+ATGR A+T L+L
Sbjct: 225 AEGVTILEGHKATRISGGPGNI-SVKAEGPEGDVMIAGSH----ILIATGRQAVTDGLDL 279
Query: 309 EAAGVTCVSNSGKIIAETEQTNVS-NIYAVGDVLEGKPELTPVA-IHAGRLLARRMFAGA 366
E GV +N G +++T ++ + ++A+GD+ G + T +A H+ + R F
Sbjct: 280 EKGGVD-FTNKGVTVSDTLRSKSNPRVWALGDI-AGHGQFTHLAGWHSSVFVRRAFFKQG 337
Query: 367 TQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNC 426
++ A T +P E VGL+E A + G D V+ + + I +
Sbjct: 338 SKASSLPLPAVTYTSP-EVAQVGLTEAEAREKFG-DAVKTSAFPFHDNDRAIAEAKT--- 392
Query: 427 YLKAVALREAPQRILGLHFVGPVAGEVIQ 455
L L +++G VG AG++IQ
Sbjct: 393 -LGEAKLVIHKGKLVGASIVGEGAGDIIQ 420
>UniRef50_A7BC28 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 455
Score = 127 bits (306), Expect = 7e-28
Identities = 120/450 (26%), Positives = 200/450 (44%), Gaps = 38/450 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+ V+G G GG A+ + G KV +++ + LGGTC+NVGCIP K +
Sbjct: 6 FDVIVLGAGPGGYLAAERLGHAGKKVALVE---------EQYLGGTCLNVGCIPTKTLLN 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A EA +G + + +NW + +K + R+ + +NG
Sbjct: 57 GAKNYLHAKEASQFGVDA---QGVAVNWTQMQAWKDQVVKGLVAGVAATERKAGVTVING 113
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE--YCISSDDIFSLGH 197
G DA + G+ T+ +++IA G P P +PG + + S I SL
Sbjct: 114 RGHL-DAPGRVTV--EGT--TYTSDHVIIATGSVPAMPPLPGTQDNPALVDSTGILSLPQ 168
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKGVVF 256
P + ++G G IG+E A +LG TV+ + + F D +A + M K V F
Sbjct: 169 IPARLAIIGGGVIGVEFASLYATLGSQVTVIEMAPEILPFMDDDLAAKARAAM--KDVTF 226
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
C VE L+ G + ++ +E+ D VLMA GR T+ + AG+
Sbjct: 227 ELGC---RVESLDGGTV----HYSKGEEKLSVEADVVLMAVGRRPATEGWGAQEAGLEI- 278
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT----QPMDY 372
N G ++ +T +TN+ N++A+GDV G+ L A + + + + + M +
Sbjct: 279 -NRGVVVDDTMRTNLPNVWAIGDV-TGRSLLAHAAYRMAEIASANILDPSAKKRGEVMRW 336
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
V VF+ E VGL+ E+A R G + V V + FI + + +
Sbjct: 337 HTVPWAVFSIPEAAGVGLT-ESAAKREGRE-VLVAKVPALMSGRFIAENGFKAPGEAKIL 394
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ++LG+H +G A E+I G A ++
Sbjct: 395 VDPKTHQVLGIHVLGAYAAEMIWGAQAVLE 424
>UniRef50_Q090H7 Cluster: Soluble pyridine nucleotide
transhydrogenase (STH)(NAD(P)(+) transhydrogenase
[B-specific]); n=2; Cystobacterineae|Rep: Soluble
pyridine nucleotide transhydrogenase (STH)(NAD(P)(+)
transhydrogenase [B-specific]) - Stigmatella aurantiaca
DW4/3-1
Length = 491
Score = 126 bits (305), Expect = 9e-28
Identities = 122/449 (27%), Positives = 200/449 (44%), Gaps = 29/449 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
++DL VIG G G + A +A +G +V V++ P LGGT N G +P K +
Sbjct: 28 EWDLVVIGSGPAGESGAVQAARMGKRVVVVE---KEPV-----LGGTAANTGTLPSKTLR 79
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ AL YG E L ++ E ++ + +L+ ++ +
Sbjct: 80 ETALYLSGYRARGLYGVETTLLHQATVSDFLYRERRVKDMERLR--IGQNLQRHGVEVLQ 137
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDI-PGAVEYCISSDDIFSLGH 197
G+G +DAHT++ + ++ +TA I++A G P+ P + P + SD++ L
Sbjct: 138 GVGSLEDAHTVVVRREGQPERRLTASFILVATGSSPYRPPLYPFGDDRVHDSDEVLELAE 197
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKGVV- 255
P +VVG G IG E A +LG P T++ L F D + + + M G+
Sbjct: 198 LPRSIVVVGGGVIGCEYACMFAALGIPVTLVDAKKELLPFLDDEFSALLAQRMSALGIQL 257
Query: 256 -FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
F + L + + L+ E E + VL+A+GR A T L LE GV
Sbjct: 258 RFGHTVDALHMPESPPALLQLTLSGGEVLEAHQ-----VLVASGRTANTAGLGLEEVGVR 312
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ + T QT V ++YAVGD + G P L ++ R+ F GA Q +
Sbjct: 313 LGTRGHVEVGATYQTAVPHLYAVGDAI-GFPALASTSMEQARVAVLHAF-GAPQTLS-PI 369
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAF-YKPTEFFIPQRNIRNCYLKAVAL 433
+ ++T E G +EE+ A+ G V F P I + ++ LK +
Sbjct: 370 LPYGIYTIPEVSMAGETEESLRAK-GIPYVAGRAPFSTNPRGQIIGE---QHGLLKLLFH 425
Query: 434 REAPQRILGLHFVGPVAGEVIQ-GFAAAV 461
RE+ ++LG+H +G +A E++ G A V
Sbjct: 426 RES-WKLLGVHVLGELATELVHVGLTAMV 453
>UniRef50_Q0F0Y4 Cluster: Soluble pyridine nucleotide
transhydrogenase; n=1; Mariprofundus ferrooxydans
PV-1|Rep: Soluble pyridine nucleotide transhydrogenase -
Mariprofundus ferrooxydans PV-1
Length = 464
Score = 126 bits (303), Expect = 2e-27
Identities = 124/444 (27%), Positives = 191/444 (43%), Gaps = 38/444 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
DYD+ ++G G G A +A +G + +++ K +GG + G IP K +
Sbjct: 2 DYDILIVGSGPAGQHAAWQAARMGKRAAIIE--------RKPSIGGAGLQTGTIPSKALR 53
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNH---IKSVNWVTRVDLREKKID 135
+AA L + G S A L EAV+ I V L + +
Sbjct: 54 EAAYLAS---RSGVQGMREASTAA---RHGVLAEAVRRKDMVIAQQESVIVKRLLKSGVA 107
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFS 194
+ G F D HTL NG+ ++++A I++A G RPH P DIP + + S I
Sbjct: 108 LIPGEASFIDEHTLEVVDANGASRQLSADVILLATGSRPHRPSDIPFDKQTVLDSTSILK 167
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGV 254
L P LVVG G I E +LG +V+ L + + AV +E
Sbjct: 168 LKRLPKSLLVVGGGVIACEFVSIFAALGVAVSVVDSHAQLLAYLSEDVVAVLAES----- 222
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVF-DTVLMATGRYALTKTLNLEAAGV 313
F N V L +++ + + E G+ ++ + VL A GR ++LN AG+
Sbjct: 223 -FDNMGVELHMQQRVVAVRREEGRTLTLLESGQKLYSEVVLYALGRVPNAQSLNTPKAGI 281
Query: 314 TCVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
T + G I + Q++V +IYAVGD++ G+P L + GR F G+ Q M
Sbjct: 282 TL--DQGWITVNKQFQSSVPHIYAVGDLI-GRPALASTGMEQGRAAVLHAFGGSGQAMP- 337
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTE--FFIPQRNIRNCYLKA 430
N+ ++ E VG +E+ A R D V V +YK + I N L
Sbjct: 338 ANLPMAIYAIPEISWVGKTEKEA-KRDQIDYV-VGRGYYKESARGQIIGDAN----GLVK 391
Query: 431 VALREAPQRILGLHFVGPVAGEVI 454
+ + R++G H VG A E+I
Sbjct: 392 LIVDAHSHRLIGAHIVGEHASELI 415
>UniRef50_A5EH40 Cluster: Putative mercuric reductase protein; n=1;
Bradyrhizobium sp. BTAi1|Rep: Putative mercuric
reductase protein - Bradyrhizobium sp. (strain BTAi1 /
ATCC BAA-1182)
Length = 477
Score = 126 bits (303), Expect = 2e-27
Identities = 120/452 (26%), Positives = 196/452 (43%), Gaps = 29/452 (6%)
Query: 14 LAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP 73
+ G + D+ VIG G+ GL+ A G + +++ +GG C+N GC+P
Sbjct: 1 MVGQTNCDVCVIGAGAAGLSVAAGTARFGLRTVLIERAR---------MGGECLNTGCVP 51
Query: 74 KKLMHQAALLGESIHEAVAYGWEVP-SLDAIKINWPALTEAVQNHIKSVNWVTRVDLREK 132
K + AA ++ H+ + L + I++ + + VQ I ++ + E
Sbjct: 52 SKALLSAA---KAAHQRETFRPPGSLELTSGPIDFAGVKDGVQAVIDAIAPHDSAERFEA 108
Query: 133 K-IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSD 190
+ + +F DA TL A ++ ITA+ VIA G P IPG +++D
Sbjct: 109 MGVAVIADTAQFVDARTLKA-----GQRRITARWFVIATGSMAVIPAIPGLDASKVLTND 163
Query: 191 DIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEME 250
IF L P +++GAG IG+E A LG TV+ R+ L + ++ + M+
Sbjct: 164 SIFQLRERPDHLVIIGAGPIGVEMAIAHRRLGCQVTVIDRASMLVNDEPELVAMLRDRMQ 223
Query: 251 QKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
Q G+ ++V+ + G + Q V +A GR + L LEA
Sbjct: 224 QDGITLVEGADLIAVDHRKDGLAVSLDLGGARQ---TITCSHVFVAAGRSPVVDGLGLEA 280
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
AGV+ G + +T+ +I+A+GDV++G P T VA H ++ R + +
Sbjct: 281 AGVS-YDRKGIAVDRRLRTSQRHIFALGDVIDG-PRFTHVAGHQAGVVVRNLAFRLPAKV 338
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
+YD + F+ E VGL+E A D + K R N +K
Sbjct: 339 NYDALPWVTFSDPELAHVGLTEARARREMDGDVAVQFVRLEKNDRAVAEHRT--NGAIKV 396
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
V R RILG + P AGE+I + AV+
Sbjct: 397 VTGRGG--RILGASILAPAAGEMIGLWCLAVQ 426
>UniRef50_A2TYU9 Cluster: Regulatory protein; n=1; Polaribacter
dokdonensis MED152|Rep: Regulatory protein -
Polaribacter dokdonensis MED152
Length = 452
Score = 126 bits (303), Expect = 2e-27
Identities = 116/445 (26%), Positives = 189/445 (42%), Gaps = 31/445 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ VIG G G A+ G KV + D GGTC GC PKK+M Q
Sbjct: 6 YDVFVIGSGIAGQTAAEICAKEGLKVAIAD---------NKAFGGTCAIRGCDPKKVMLQ 56
Query: 80 AALLGESIHEAVAYGW-EVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A + + G+ ++P KINW + + N ++V T DL + ID +
Sbjct: 57 FAEITQKAKHLKGLGFTKLP-----KINWDDILKFKNNFTEAVPKSTEEDLADLDIDLYH 111
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
+F + + K + A VIA G P GA E+ +SDD F+L
Sbjct: 112 QSPKFISKNKISV-----EGKTVIADKFVIATGLIPRTLKFKGA-EFLKTSDDFFNLKKL 165
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVFH 257
P +G+GYIG+E L++LG ++ R L F++ + + + + GV F
Sbjct: 166 PKSVTFIGSGYIGMEFCFLLSTLGCKVIMIDRGPRILSQFEKSLTEKIKQNLANNGVEFI 225
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ LSVEK G+ K + +E + +GR + LNLE A +
Sbjct: 226 FEADVLSVEK---GRKKLKLNYKVGKEERSLKSHIIFNTSGRVPSLEALNLENAAIKA-D 281
Query: 318 NSGKIIAE-TEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
SG ++ + + ++ +++A GDV LTP++ G ++ + ++ V
Sbjct: 282 ESGVLVNDYLQSSSAKHVFACGDVSSKSFPLTPLSGLQGYIVGHNILKARSKKFKNPLVP 341
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+ VFT VG EE A R+ KV A + ++ ++ Y + + +
Sbjct: 342 SIVFTDPNLAMVGYLEEEAKKRYKNTKVYKGDA----SNWYNAKKENAPFYAYKIIVNKR 397
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAV 461
+I+G H + A E I F A+
Sbjct: 398 TDQIVGAHLLSSEANETINIFTTAI 422
>UniRef50_Q88ZF2 Cluster: Glutathione reductase; n=4;
Lactobacillales|Rep: Glutathione reductase -
Lactobacillus plantarum
Length = 443
Score = 125 bits (302), Expect = 2e-27
Identities = 129/447 (28%), Positives = 191/447 (42%), Gaps = 38/447 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ VIGGG G A A G V +++ WG GTC N GC PKK++
Sbjct: 5 YDVVVIGGGPAGNAMASGLKAQGKTVLIVE-------ADLWG--GTCPNRGCDPKKILLS 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A ++ G + A KI+WPAL + + +N T L + I ++G
Sbjct: 56 AVEARQAAQHLQGQGL----IGAPKIDWPALMAHKRGYTDGINDGTLNGLTGQDIATLHG 111
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
F+ + L + ++A + VIA G RP I G EY +S D L P
Sbjct: 112 QAHFQSDNQLAV-----GDRVVSATDYVIATGQRPAILPITGH-EYFKTSTDFLDLDQMP 165
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRS-VPLRGFDQQMAQAVTSEMEQKGVVFHN 258
+ VG GY+G E A N+ G V+ + PL+ FD + + + + M G+ F
Sbjct: 166 KRVTFVGGGYVGFELATIANAAGADVHVIHHNDRPLKAFDADLVKDLMAAMTADGITFDL 225
Query: 259 KCVPLSVEKLETG-QLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
++ K TG QL T + E D V+ + GR L L GVT
Sbjct: 226 NTDVQAITKTATGLQL--------TADNFELTTDLVISSAGRIPNADQLGLANVGVT-FD 276
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGK-PELTPVA-IHAGRLLARRMFAGATQPMDYDNV 375
G + + QT +IYA+GDV + P+LTPVA A L+ GA + Y V
Sbjct: 277 RHGIQVNDHLQTANPHIYAIGDVSDTPVPKLTPVAGFEARYLVGELTHPGAA--IKYPVV 334
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALRE 435
T VF + VG+S A+A D+ V T++F R V + +
Sbjct: 335 PTQVFAAPKLAQVGIS--AAVATEHPDEYRV--NTLDMTKWFTYYRFGAQQAQAKVVVAK 390
Query: 436 APQRILGLHFVGPVAGEVIQGFAAAVK 462
A +++G + VA E+I F ++
Sbjct: 391 ASGQVVGATLLSDVADEMINYFTLLIE 417
>UniRef50_Q38UF8 Cluster: Glutathione reductase; n=3;
Lactobacillus|Rep: Glutathione reductase - Lactobacillus
sakei subsp. sakei (strain 23K)
Length = 444
Score = 125 bits (302), Expect = 2e-27
Identities = 107/378 (28%), Positives = 163/378 (43%), Gaps = 29/378 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D VIGGG GGLA A + + V + WG GTC N GC PKK+++
Sbjct: 5 FDTIVIGGGPGGLAAAYRLAEQQSVLVV--------ENDLWG--GTCPNRGCDPKKMLYS 54
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + H + G S INWP L + + + T L+ I V G
Sbjct: 55 AVEAIDHQHTLQSSGLVGTSY----INWPQLMAFKRQYTTQIPDGTLNGLQSAGIRTVTG 110
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
F H L + + TA + +IA G P P I G + +S+ L H P
Sbjct: 111 TAHFIADHHLRV-----GETDYTADHFIIATGQTPTLPAIEGR-DLLQTSNQFLDLDHLP 164
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVFHN 258
K +GAGYI +E A + G ++ + LR F + M + + ++ KGV FH
Sbjct: 165 AKIAFIGAGYIAIELANIAATAGAEVHIIQHNKRILRDFPEAMTTELITSLQNKGVQFHF 224
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+ V + G + D A GR+A LNL AA + +
Sbjct: 225 ETTVTKVYETTKGLVLNNAGGFTL------TVDAAFAALGRHANIDELNLPAADIA-TGH 277
Query: 319 SGKIIAETEQTNVSNIYAVGDVLEG-KPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
G + E ++ +YA+GDV++ +P+LTPVA GR +A ++ + P+ Y +
Sbjct: 278 HGIQVDEHLVSSNPRVYAIGDVVDRPQPKLTPVAGFEGRYVANQLLQTNSDPIAYPLIPH 337
Query: 378 TVFTPLEYGCVGLSEETA 395
TV+ + G+S +TA
Sbjct: 338 TVYASPQISQAGVSVQTA 355
>UniRef50_Q1K1S1 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: FAD-dependent
pyridine nucleotide-disulphide oxidoreductase -
Desulfuromonas acetoxidans DSM 684
Length = 517
Score = 125 bits (302), Expect = 2e-27
Identities = 118/452 (26%), Positives = 197/452 (43%), Gaps = 28/452 (6%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T +YDL V+G G GG A A A + G V V++ G KWG K +
Sbjct: 5 TVEYDLCVLGCGPGGFAGAMRAFDFGKHVCVVEGGEIGGAGVKWG--------ALASKTM 56
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDL------- 129
+ + + Y + ++D ++N + EAV+ + +T+++
Sbjct: 57 WELSKDYSIAAKQDRGYQSQHLTVDFSEVN-ATIEEAVKE--RQYQMLTQLETFSPRRWQ 113
Query: 130 REKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCIS 188
E I YV G F D HT+ L +G+ + I AKN +I+ G P Y ++ + +
Sbjct: 114 GEGSITYVRGWASFVDRHTVEVCLDDGTTQHIHAKNFLISTGSHPRGYGNLQVDQDKIFN 173
Query: 189 SDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV--RSVPLRGFDQQMAQAVT 246
S+ I L P + L++GAG +G E A + G LV + L D+ ++ V
Sbjct: 174 SNGIHRLKKFPKRLLILGAGVVGCEYATIFANFGQTQVHLVDHKDRVLSYEDRDVSAFVE 233
Query: 247 SEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTL 306
+E GVV H + + + L A + +V D L++ GR + L
Sbjct: 234 QSLEGAGVVLHQSATLQDIHRRQ-DYLAAVLDFPDGHSEVIEV-DAALISVGRQPNLQHL 291
Query: 307 NLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGA 366
L+ G+ +S +G + + NI+A GDV P L +A R+ A+ MF A
Sbjct: 292 RLDKIGID-ISENGFLTTGVDCRVDGNIFACGDV-TCHPNLVNIAELEARMAAKEMFCRA 349
Query: 367 TQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNC 426
+P++Y N++ +F VGLSEE A+ + +V + Y + + R R
Sbjct: 350 IRPLNYCNMSAIMFLNPSVATVGLSEEQCQAKKLSYRVA--YVAYAMSSRPLAMRAKRG- 406
Query: 427 YLKAVALREAPQRILGLHFVGPVAGEVIQGFA 458
++K + +A +ILG+ GP V+ A
Sbjct: 407 FVKILVTDDAEMKILGMRSAGPQVSNVVLSIA 438
>UniRef50_A0Q826 Cluster: Dihydrolipoamide dehydrogenase; n=7;
Francisella tularensis|Rep: Dihydrolipoamide
dehydrogenase - Francisella tularensis subsp. novicida
(strain U112)
Length = 472
Score = 125 bits (302), Expect = 2e-27
Identities = 119/445 (26%), Positives = 209/445 (46%), Gaps = 34/445 (7%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+ +IGGGSGGL+ A AV +GAKV + +G K +GG C+N GC+P K + +A
Sbjct: 5 DICIIGGGSGGLSVAAGAVQMGAKVVLC-------EGNK--MGGDCLNYGCVPSKAIIEA 55
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREK-KIDYVNG 139
+ + +++A A+G + + + I+I++ + E ++ I + V+ E ++ +
Sbjct: 56 SRVIAKVNKAQAFGINIDN-NNIEIDYKKVQEHIKTTIAKIEPHDSVERFETLGVNVIQE 114
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLGHP 198
+ D +T+ A I A+ IVIA G R P I G E ++++ IF L
Sbjct: 115 YAQIIDQYTVKA-----GDNFIKARYIVIATGSRAAIPKIKGLAEVNYLTNETIFDLKEK 169
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRG-FDQQMAQAVTSEMEQKGVVFH 257
P ++VG G IG+E A LG T+ S + G D + + E ++ G+
Sbjct: 170 PEHLMIVGGGPIGVELAQAYALLGSKVTIFEASDTILGVLDNDCRKIILKEFDRLGI--- 226
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ +++ ++ + +G +L+A GR L+L+ G+ S
Sbjct: 227 SIITNVNISEIAQDDQEINLYCGSKLYQGSH----LLIAAGRVPNLDKLDLDNVGIKYTS 282
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
K + +TN NIYA+GDV+ G HAG ++ +F + +DY+++
Sbjct: 283 RGIK-VDSCLRTNHKNIYAIGDVVGGYQFTHVAGYHAGVVIQNILFKLPIK-VDYNSLPW 340
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
+++T E VG + A HGA ++ Y+ + + + N +K VA+ +
Sbjct: 341 SLYTSPEVAYVGQNIAQA-QTHGA---KILKLSYQNNDRAVASL-VTNGLIK-VAINKKG 394
Query: 438 QRILGLHFVGPVAGEVIQGFAAAVK 462
ILG VG A E+I + A+K
Sbjct: 395 Y-ILGATIVGENASELIVQWTIAIK 418
>UniRef50_Q6AAX8 Cluster: Pyridine nucleotide-disulphide
oxidoreductase; n=8; Actinomycetales|Rep: Pyridine
nucleotide-disulphide oxidoreductase - Propionibacterium
acnes
Length = 466
Score = 125 bits (301), Expect = 3e-27
Identities = 129/447 (28%), Positives = 201/447 (44%), Gaps = 40/447 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ VIG GSG ++ + + ++D GGTC+NVGCIP K+
Sbjct: 4 YDIVVIGSGSGNTILDEDFAD--RRAAIID---------SGAFGGTCLNVGCIPTKMFVL 52
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLRE--KKIDYV 137
A S EAV G ++ A ++ ++ + + I S++ + R+ ID
Sbjct: 53 PADFASSPSEAVRVGVDLQFRGA---SFASIRDRIFGRIDSIS-KAGLSYRQGLDNIDVY 108
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCIS-----SDDI 192
G F DAHTL + G + ITA IV+A G RP PD+PG + ++ SD I
Sbjct: 109 TGEAAFIDAHTL----EVGGRC-ITADQIVLAAGSRPRVPDVPGLDDPSMAGLIHTSDTI 163
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQ 251
L P + +++G G I E A + LG TV+ RS LR D++++Q T +M +
Sbjct: 164 MRLAELPQRLVILGGGLIAAEFAHIFSGLGSQVTVINRSGRMLRHEDREISQRFTEQMGR 223
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
+ V + V++ G L + + + D VL ATGR + LNL AA
Sbjct: 224 R-VRLRMAEGLVGVDRDPGGHLVVLTVDGDGVDYDYPA-DVVLNATGRVSNGDRLNLPAA 281
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMF-AGATQPM 370
GV + ++ + ++TNV +I+A+GDV EL VA H R++ +
Sbjct: 282 GVDVDDDGFVVVDKHQRTNVEHIWALGDVC-SPWELKHVANHEARVVRHNLLHPDDLASS 340
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
++ V VF+ + VG +E+ L Y Y + + +C
Sbjct: 341 NHCFVPHAVFSNPQVASVGATEQGLL--QSDTPYAAYLQEYADVAYGWAMEDEGHC---- 394
Query: 431 VALREAPQ--RILGLHFVGPVAGEVIQ 455
V L PQ +LG H +GP A +IQ
Sbjct: 395 VKLLGDPQTRTLLGAHIIGPQASTLIQ 421
>UniRef50_Q68VU4 Cluster: Dihydrolipoyl dehydrogenase; n=11;
Rickettsiales|Rep: Dihydrolipoyl dehydrogenase -
Rickettsia typhi
Length = 459
Score = 125 bits (301), Expect = 3e-27
Identities = 118/444 (26%), Positives = 196/444 (44%), Gaps = 29/444 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+AVIGGG GG A A L KV +++ K LGG C+N GCIP K + +
Sbjct: 4 YDVAVIGGGPGGYVAAIRAAQLKKKVVLIE---------KSHLGGVCLNWGCIPTKSLLK 54
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A + E I A YG +V +IN + E + ++ ++ L++ K+ +NG
Sbjct: 55 SAEVFEYIKHAKDYGIDV---GIAEINIQKIVERSREIASTLACGVQLLLKKNKVTIING 111
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLGHP 198
+ F + + K + A NI+IA G RP + +S + +
Sbjct: 112 VASFGEN----KVINVNDKPTVKANNIIIATGARPKILQGFEPDITQIWTSKEAMIPQYV 167
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P +++G+G IG+E A F NS+G T++ + L D ++A EQKG+
Sbjct: 168 PKSMIIIGSGAIGIEFASFYNSIGVDVTIIEAYNRILPSEDTEIAGIAHKIFEQKGIKIL 227
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTV-LMATGRYALTKTLNLEAAGVTCV 316
+ K Q K + E + + + + T+ LMA G A + L LE V V
Sbjct: 228 TNA---KLIKQTKSQNKIEVE-LELEGKKQKLQATILLMAVGITANIENLGLEKTKVQ-V 282
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
N + QT S IYA+GDV G P L A H G + A + ++ N+
Sbjct: 283 ENGYIVTNGLMQTAESGIYAIGDV-SGVPCLAHKASHEGIIAAESIAGLKPNSINKHNIP 341
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+++ + VGL+EE +A+ ++++ ++ + N ++
Sbjct: 342 YCIYSSPQIASVGLTEE--VAKDLGYEIKIGRFPFRANGKALVSGNSYGLIKTIFDVKTG 399
Query: 437 PQRILGLHFVGPVAGEVIQGFAAA 460
+LG H +G E+IQG+ +
Sbjct: 400 --ELLGAHMIGLEVTELIQGYVVS 421
>UniRef50_Q1K470 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=1;
Desulfuromonas acetoxidans DSM 684|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
precursor - Desulfuromonas acetoxidans DSM 684
Length = 492
Score = 125 bits (301), Expect = 3e-27
Identities = 123/453 (27%), Positives = 205/453 (45%), Gaps = 36/453 (7%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
YDY+L V+G G+ GL A + GA+V +++ +GG C+N GC+P K +
Sbjct: 15 YDYNLVVVGAGAAGLVSAYLSAAAGARVALVEQAQ---------MGGDCLNRGCVPSKAL 65
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD-LREKKIDY 136
++A L + + +A YG +P D + +++ + E VQ I+++ V+ + ++
Sbjct: 66 IRSAHLAQQMRQADHYG--LPGQD-VDVDFAQVMERVQQTIRTIEPHDSVERYQSLGVEC 122
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIFS 194
+G H + + +T + IV+A G P P++ G +V+Y +SD I+S
Sbjct: 123 FHGQAHLLSGHEVAV-----GDRVLTTRRIVLATGATPVVPELAGLDSVDY-YTSDTIWS 176
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKG 253
L P + +VVG G IG E + N LG +V L+ D+ + + V +G
Sbjct: 177 LRQKPRRLIVVGGGPIGCELSQAFNRLGSQVVQVVHGERLLKREDRAVCELVQQVFHDEG 236
Query: 254 VVFHNKCVPLSVEKLETG-QLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
V C V + + L + E G D +L A GR +T+ E G
Sbjct: 237 VELCLNCDLQHVARQQDEIVLTCHVGDEERTVHG----DALLFAVGRQPMTQGFGFEVLG 292
Query: 313 VTCVSNSGKIIAE-TEQTNVSNIYAVGDVLEGKPELTPVAIH-AGRLLARRMFAGA-TQP 369
T V G + A+ T +T+V +IY GDV+ G + T +A H A +F +
Sbjct: 293 GT-VDRRGALQADGTLRTSVPSIYCAGDVV-GPYQFTHMAAHQAATASLNALFDRIWRRR 350
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
+D V T F E VGL+E+ AL + A EV Y + + +++
Sbjct: 351 VDVSLVPWTTFVDPEVARVGLNEQDALRQKIA--YEVTRLDYGELDRAVTDTTTPG-WIQ 407
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + ILG+ VG AG+ + F A+K
Sbjct: 408 VLTV-PGKDTILGVTIVGAHAGDCLAEFVLAMK 439
>UniRef50_Q8RDF1 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Thermoanaerobacter|Rep: Dihydrolipoyl dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 461
Score = 124 bits (300), Expect = 4e-27
Identities = 117/397 (29%), Positives = 182/397 (45%), Gaps = 40/397 (10%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T +YDLAVIGGG GG A +A GAKV + + K LGGTC+N GCIP K
Sbjct: 6 TREYDLAVIGGGPGGYVAAIKAAKKGAKVALFE---------KDKLGGTCLNRGCIPTKA 56
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVT---RVDLREKK 133
+AA + + +A +G++ I+IN+ + V+ V + + L+ K
Sbjct: 57 YARAAEVYGILKKAKEFGFD------IQINYFDYAQVVKRKDTIVGELVEGIKALLKANK 110
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA-VEYCISSDDI 192
I+ N + +I G K I AKNI+IA G P I G + ++SD I
Sbjct: 111 IEVFNKEAKVDKEKNVIF---EGEK--IKAKNIIIATGSSPAELPIEGIDSKNVLNSDTI 165
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEME 250
+ P ++G G IG+E A +N G V V +P L D++++ AV +
Sbjct: 166 LEITSLPKSLCIIGGGVIGMEFAFIMNQFGVEVYV-VEMMPNILPSLDKKVSSAVKFAAQ 224
Query: 251 QKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
++G+ + +VEK+E +N+ R D + + ++ + LN
Sbjct: 225 KRGIKIYTSS---TVEKVE-----EEGENSVVTIRSGDDIKKISVDKVFVSIGRKLNTSI 276
Query: 311 AGVTCVSNSGK---IIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGAT 367
+ + K + E +TN+ ++AVGDV GK L VA G + +F G +
Sbjct: 277 GPIVDLLEFDKKAIKVDEHMRTNIEGVWAVGDV-TGKMMLAHVASSQGEVAVDNIF-GKS 334
Query: 368 QPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKV 404
+ +DY + VFT E G G +EE A + G KV
Sbjct: 335 RTLDYYKIPAAVFTEPEIGYFGYTEEEAKEKFGEIKV 371
>UniRef50_Q0AVI0 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Dihydrolipoyl dehydrogenase - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 462
Score = 124 bits (300), Expect = 4e-27
Identities = 117/438 (26%), Positives = 202/438 (46%), Gaps = 31/438 (7%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
DL VIGGG GG A A LG KV +++ K LGGTC+N GCIP K ++
Sbjct: 3 DLLVIGGGPGGYVAAIRARQLGMKVALVE---------KDKLGGTCLNRGCIPTKTYYRH 53
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
A + S+ + ++ + A +++ ++ + L+ ++ + G
Sbjct: 54 AEIMRSLQRLDEFCIQLDAEPA-RLDMAGTRARKDAVVEQMAGGVADLLQAHGVEVIRGE 112
Query: 141 GEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPD-IPGA-VEYCISSDDIFSLGHP 198
++ ++ G ++ I A+ ++IA G P +PGA + ++ +++
Sbjct: 113 AVVEEP----GRVRVG-EESIRAERLLIATGSESIRPAALPGAALPGVLTCEELLERSAI 167
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKGVVF 256
PG+ L++G G IG+E A + G TVL S+P L DQ++A+ ++ +++G+
Sbjct: 168 PGRLLIIGGGVIGMEFACIFQAFGSQVTVL-ESLPRALAFLDQEIARRMSVLFKRQGIEI 226
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
VE + T ++ + + D VL+A GR +T LNLE GV
Sbjct: 227 KTGA---KVESINTQDDHLLITASDKKGNVQYEADLVLLAVGRSPVTAGLNLEKLGVETE 283
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
K+ + E ++V IYA+GDV+ G P L VA GR+ RM AG ++Y+ +
Sbjct: 284 QGFIKVNQDYE-SSVGGIYAIGDVI-GPPMLAHVASEEGRVAVERM-AGMDSRLNYEAIP 340
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+FT E VGL++E A R K+ + + + +K +
Sbjct: 341 HCIFTFPEIAAVGLTQEEAAPRGIDCKIGKFQFAANGKAVAMGE---SEGLIKVIC--SP 395
Query: 437 PQRILGLHFVGPVAGEVI 454
+LG+H +GP A ++I
Sbjct: 396 DDTVLGVHIIGPHASDLI 413
>UniRef50_Q1Q2Y9 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Dihydrolipoyl
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 472
Score = 124 bits (299), Expect = 5e-27
Identities = 115/446 (25%), Positives = 202/446 (45%), Gaps = 29/446 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DLA+IGGG G A +A G K +++ K +GGTC++ GCIP K +
Sbjct: 6 FDLAIIGGGPAGYVAAIKAAQSGLKTALIE---------KEKVGGTCLHKGCIPTKTLLY 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A L A YG SL+ +++P + + +K + + L++ +D +
Sbjct: 57 SAELYRKFANAGEYGITTGSLN---VDYPLIHRRKEYVVKRLFQGVQSLLKKNGVDVFSA 113
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFSLGHP 198
G + I KNI++A G P P +IP +Y ++SDDI
Sbjct: 114 EGRIISNQEVSIVSDGIETNRIKVKNIILATGSAPFIPKNIPYDKKYVLTSDDILLREEI 173
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P ++VG G +G+E A N+ G TVL + L D+++ V + + ++GV
Sbjct: 174 PKSIIIVGGGAVGIEFACLFNAFGTEVTVLELLEDILPSEDKEINGTVKNLLIRRGV--- 230
Query: 258 NKCVPLSVEK--LETG-QLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
N S+EK +E G +L+ + N + R D +L+A GR L + +E
Sbjct: 231 NVLTQTSLEKVEIENGVKLEIKGVNDISGNREFLHADLLLLAAGRVPLLDNIGIEEMS-- 288
Query: 315 CVSNSGKIIAETE--QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
++ G+ + E +T+ +YA+GD+ G P L AI+ G L + ++
Sbjct: 289 -LNFDGQYLRTNEGMETSQRGVYAIGDI-TGAPLLAHKAINEGILSVTHLTGKDMHIINR 346
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
N+ V++ + +GL+++ A KV++ + I + + ++K V+
Sbjct: 347 KNIPRVVYSFPQVASIGLTQKE--AEEMGYKVKIGKFPFAANSMAIIEGESLDGFVKIVS 404
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFA 458
E ILG+H +G GE + G +
Sbjct: 405 -EEKYGEILGVHAIGHHVGEWMWGLS 429
>UniRef50_A7GZF3 Cluster: Probable pyridine nucleotide-disulfide
oxidoreductase YkgC; n=2; Campylobacter|Rep: Probable
pyridine nucleotide-disulfide oxidoreductase YkgC -
Campylobacter curvus 525.92
Length = 446
Score = 124 bits (299), Expect = 5e-27
Identities = 107/380 (28%), Positives = 168/380 (44%), Gaps = 28/380 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ VIG G G A +A LG KV +++ SPQ GGTC+N+GCIP K +
Sbjct: 3 YDIIVIGFGKAGKTLAAKAGALGKKVALIER---SPQM----YGGTCINIGCIPTKRLVT 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA + ++ V + S+ + + +++ N D ID ++G
Sbjct: 56 AAKEAQFVNNNVEGDYYTLSIQT--------KDKLITALRAKNLGMLKD--NPNIDVIDG 105
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
+G F D +++ +GSK I IVI G + + +S +I +L P
Sbjct: 106 VGYFLDKNSVEILTADGSKCLIDGDTIVINTGSKEADAPFEVKSDIAYTSSEILNLKTLP 165
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFHNK 259
++VG G+IGLE A G T++ R ++ D +A +V + +G+
Sbjct: 166 KHLVIVGNGFIGLEFASMFAGFGSKVTIVGRGKFMKNEDDDVANSVKEALVAQGIEILED 225
Query: 260 CVPLSVEKLETGQLKARWQNTETQERGEDVF-DTVLMATGRYALTKTLNLEAAGVTCVSN 318
C L R N + + D L+A GR A+T+ LNL+ GV
Sbjct: 226 C--------NISSLMGRGLNFSQGGMSKSIIADAFLLAMGRKAVTEGLNLDKVGVKIDEK 277
Query: 319 SGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFA-GATQPMDYDNVAT 377
++ E QT+ NIYAVGDV G T ++ R++ ++F G + A
Sbjct: 278 GNIVVNEFLQTDTPNIYAVGDV-RGGELFTYTSLDDFRIVFDKIFGKGERSTKNRAIHAN 336
Query: 378 TVFTPLEYGCVGLSEETALA 397
T+FT VGLS++ A A
Sbjct: 337 TLFTQTPLAKVGLSQKEATA 356
>UniRef50_Q4A6P9 Cluster: Putative mercuric reductase; n=1;
Mycoplasma synoviae 53|Rep: Putative mercuric reductase
- Mycoplasma synoviae (strain 53)
Length = 459
Score = 124 bits (298), Expect = 7e-27
Identities = 105/384 (27%), Positives = 183/384 (47%), Gaps = 24/384 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP-KKLMH 78
YD+ +IG G GG A + KV +++ P+ +GGTC+NVGC+P K H
Sbjct: 4 YDVIIIGWGKGGKTLANKLGLSNKKVAIIE---KDPKM----VGGTCINVGCLPTKSYTH 56
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ + ES +E +K L + + K+ + + K +D
Sbjct: 57 YSHVFVESSKLGYKTSYETGKKAYVKTLKHKLEFVKKLNQKNFELLNK----NKNVDIYM 112
Query: 139 GLGEFKDAHTLIATLKNGSKK-EITAKNIVIAVGGRPHYPDIPGAVE--YCISSDDIFSL 195
G +F + + L + KK ++TAKNI+I G +I GA + + S+DI +L
Sbjct: 113 GSAKFLSDYEVEVNLNSNKKKVKLTAKNIIIGTGSVSRKLNIEGAAKSRFVKYSNDILNL 172
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGV 254
P K LVVGAG+IGLE A + + G TV + + D++ ++ + ++++G+
Sbjct: 173 RTLPKKLLVVGAGFIGLEFASYFANFGTQVTVAQYNNDFMPNEDKEDSKFILDTLKKQGI 232
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
F + EK + + + + + ++ ++ FD VL++ GR T L LE +
Sbjct: 233 KFEFNT---TCEKFKDLKSQVQVSLSNKTKKYKEKFDAVLISAGRIPNTLNLGLENTKIK 289
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
+ N + + QTNV IYA+GDV +G P T +++ R+++ ++ + + DN
Sbjct: 290 VLDNKAIEVNKYLQTNVKGIYAIGDV-KGGPMFTYISLDDYRIVSDQLLK-TKKNRNLDN 347
Query: 375 ---VATTVFTPLEYGCVGLSEETA 395
V T VF + VGL+ + A
Sbjct: 348 RPLVPTNVFIRPSFARVGLNLKQA 371
>UniRef50_Q0SUA0 Cluster: Pyridine nucleotide-disulphide
oxidoreductase; n=9; Bacteria|Rep: Pyridine
nucleotide-disulphide oxidoreductase - Clostridium
perfringens (strain SM101 / Type A)
Length = 457
Score = 124 bits (298), Expect = 7e-27
Identities = 115/386 (29%), Positives = 184/386 (47%), Gaps = 28/386 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
Y+ +IG G GG A LG KV +++ + K GGTC+NVGCIP K +
Sbjct: 4 YEYIIIGFGKGGKTLAGYLGKLGKKVAIIE------KSDKM-YGGTCINVGCIPTKTLVN 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWP-ALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ + S+++ + E I AL EA+++ K+ N + + +D N
Sbjct: 57 KSKV--SLYKGLNTFEEKAREYRKSIEEKNALIEALRD--KNYNMLNN----NENVDVFN 108
Query: 139 GLGEFKDAHTLIATLKNGSKKEIT--AKNIVIAVGGRPHYPDIPG--AVEYCISSDDIFS 194
G F ++T I L N K++I + I I G P+I G + +S I
Sbjct: 109 GTASFI-SNTEI--LINSEKEDIILEGEKIFINTGATTIIPNIQGIKSSSKIYNSTTIME 165
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKG 253
L P ++VG GYIGLE A S G TV+ + G D+ +++++ +E+KG
Sbjct: 166 LKELPKHLVIVGGGYIGLEFASIYASFGSKVTVIEAFDRIAGREDEDISKSIKEILEKKG 225
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ F S E++ G+++ ++N+ E + D VL+A GR T+ LNLEAAGV
Sbjct: 226 IEFLLGSKVKSFEEIH-GEVEVSYENS-LGELNKITGDAVLIAIGRKPNTEELNLEAAGV 283
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFA-GATQPMDY 372
+ +TN+ NI+A+GDV G P+ T +++ R++ +F G D
Sbjct: 284 KVTERGAIEVNNKLKTNIPNIWAIGDV-NGGPQFTYISLDDFRIIKDNLFGEGKRSTDDR 342
Query: 373 DNVATTVFTPLEYGCVGLSEETALAR 398
+ +VF VGLSE+ AL +
Sbjct: 343 KFIPYSVFIEPNLSRVGLSEKEALEK 368
>UniRef50_Q82L58 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Dihydrolipoyl
dehydrogenase - Streptomyces avermitilis
Length = 478
Score = 123 bits (297), Expect = 9e-27
Identities = 128/448 (28%), Positives = 200/448 (44%), Gaps = 36/448 (8%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+ VIGGG+GG + A A LG V + + + +GGTC++ GCIP K M A
Sbjct: 8 DVIVIGGGTGGYSAALRAAALGLTVVLAE---------RDKVGGTCLHRGCIPSKAMLHA 58
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
A L + I EA +LD I+WPAL + + + L ++ V G
Sbjct: 59 AELVDGIAEARERWGVKATLD--DIDWPALVATRDDIVTRNHRGVEAHLAHARVRVVRGS 116
Query: 141 GEFKDAHTLIA-----TLKNGSKKEITAKNIVIAVGGRPHYPDIPGAV---EYCISSDDI 192
++ L G+ + IV+A G RP +PG V ++SDD
Sbjct: 117 ARLTGPRSVRVEGAPDDLPGGAGDFTARRGIVLATGSRPR--TLPGLVPDGRRVVTSDDA 174
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV---RSVPLRGFDQQMAQAVTSEM 249
P LV+G G IG+E A F S+G T++ R VPL D +++ +T +
Sbjct: 175 LFAPGLPRSVLVLGGGAIGVEYASFHRSMGAEVTLVEAADRIVPLE--DVDVSRHLTRGL 232
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
+++G+ L E LE G ++AR + + R + + +L+A GR +T L+L
Sbjct: 233 KKRGIDVRAGARLLDAELLEAG-VRARVRTVRGEIRTLEA-ERLLVAVGRAPVTDGLDLA 290
Query: 310 AAGVTCVSNSGKIIAETE--QTNVSNIYAVGDVLEGKP-ELTPVAIHAGRLLARRMFAGA 366
AAG+ ++ + +T V I+ VGD+L L + G +A +
Sbjct: 291 AAGLATDERGFVTPSDWDRLETAVPGIHVVGDLLPPPSLGLAHASFAEGLSVAETLAGLP 350
Query: 367 TQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNC 426
+ P+DY V ++ + VGL E A AR +V+V T + R
Sbjct: 351 SAPVDYAAVPRVTYSSPQTASVGLGEAEARAR--GHEVDV--NTMPLTAVAKGMVHGRGG 406
Query: 427 YLKAVALREAPQRILGLHFVGPVAGEVI 454
+K VA E ++LG+H VGP E+I
Sbjct: 407 MVKVVA-EEGGGQVLGVHLVGPHVSEMI 433
>UniRef50_Q1GLP7 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=17;
Alphaproteobacteria|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Silicibacter sp.
(strain TM1040)
Length = 501
Score = 123 bits (297), Expect = 9e-27
Identities = 124/442 (28%), Positives = 192/442 (43%), Gaps = 29/442 (6%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
YDYDL VIG G G A +A L +V V+D K LGG V+ G +P K +
Sbjct: 8 YDYDLIVIGSGPSGRTAAIQAAKLKRRVLVID--------RKDRLGGVSVHTGTVPSKTL 59
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKI-NWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
+ L E YG D IK + A +H V+ V +D
Sbjct: 60 RETVLNLTGWRERSFYGRAYRVKDQIKAEDLKARLHMTLDH--EVD-VLEHQFNRNHVDM 116
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPD-IPGAVEYCISSDDIFSL 195
+ G+ F + + ++ G +T + +IA G R + PD +P + D+ +
Sbjct: 117 LAGMAHFTGPNEVEVEVEAGDTTRVTGEKFLIATGTRTYRPDSVPFNGTTVVDGDEFLEM 176
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGV 254
P +VVGAG IG+E A ++L T++ R L D+ + Q T ++ + GV
Sbjct: 177 AEIPRSLIVVGAGVIGVEYATMFSALDVRVTLIEPRDTFLDFIDRTLIQEFTHQIRENGV 236
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
S+E E ++ +N RGE +L A GR T LNL+A G+
Sbjct: 237 DLRLGSAIESIED-EGSHIEVTLENGR-HVRGE----MLLFAAGRMGNTDRLNLKAVGLE 290
Query: 315 CVSNSGKIIAE--TEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
+ G++ E T QT VS+IYA GDV+ G P L ++ GR+ A T P +
Sbjct: 291 -TDHRGRLEVERKTYQTKVSHIYATGDVI-GHPSLASTSLQQGRVAACHAMDVPTVP-ES 347
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
+++ E G+SEE R +V + F + + I + + LK +
Sbjct: 348 PWFPYGIYSVPEMSTCGMSEEELKERGVPYEVGIAR-FRETSRGHI--MGLEHGMLKMLF 404
Query: 433 LREAPQRILGLHFVGPVAGEVI 454
+ +R+LG+ VG A E+I
Sbjct: 405 SLKT-RRVLGVQIVGEGATELI 425
>UniRef50_A3DNK1 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Staphylothermus marinus F1|Rep: Dihydrolipoamide
dehydrogenase - Staphylothermus marinus (strain ATCC
43588 / DSM 3639 / F1)
Length = 451
Score = 123 bits (297), Expect = 9e-27
Identities = 118/441 (26%), Positives = 184/441 (41%), Gaps = 39/441 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ V+G G GG A G KV V++ + LGG C N GC+P K ++
Sbjct: 2 YDVVVVGAGVGGYPAAIYLARHGLKVAVIE---------EHLLGGECTNYGCVPSKALYN 52
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A E+ G I+W L+ V + +K L +D +N
Sbjct: 53 IA---EAFRTIEKVGGNA------NIDWNNLSRWVSSVVKETRNGIEYLLESYGVDIINS 103
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLGHP 198
K +K G+ I+ KNI++A+G P P++ +Y +S+ ++F +
Sbjct: 104 KAVLKKD----TAIKIGNDI-ISPKNIILALGTDPKPLPNVNFDGKYLLSNREVFYMEEK 158
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKGVVF 256
P K L++G G IG+E A + LG T+ V ++P L D+ ++ + + +K V
Sbjct: 159 PEKILIIGGGVIGVEAAYTFSQLGIDVTI-VEAMPNILPFLDKDISLTMKRFLREKNVKI 217
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
+ + +E ++KA+ N E D +L+A GR T + LE V
Sbjct: 218 YENTFVEKI-TIENNKVKAKLSNNNLIET-----DKILVAIGRKPKTTNIGLETVRVETT 271
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ E QT IYAVGDV+ G+P L AI AR + + + Y V
Sbjct: 272 QKGFIKVNEKYQTTNPRIYAVGDVI-GEPLLAHKAILESIAAARNILGEESFSLSYHLVP 330
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
T+F+ LE +G +E R +K Y P R + Y L +
Sbjct: 331 QTIFSGLEIAWIGYTE-----RELREKGIKYRRIRMPVSHLSAVRIKDSKYSYVKILMDE 385
Query: 437 PQRILGLHFVGPVAGEVIQGF 457
G+ V P+A EVI F
Sbjct: 386 NNVPYGIFVVSPLASEVISSF 406
>UniRef50_P0A9P3 Cluster: Dihydrolipoyl dehydrogenase; n=182;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Shigella
flexneri
Length = 474
Score = 123 bits (297), Expect = 9e-27
Identities = 112/382 (29%), Positives = 179/382 (46%), Gaps = 31/382 (8%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMHQA 80
+ V+G G G + A +LG + +++ LGG C+NVGCIP K L+H A
Sbjct: 9 VVVLGAGPAGYSAAFRCADLGLETVIVERYNT--------LGGVCLNVGCIPSKALLHVA 60
Query: 81 ALLGES---IHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
++ E+ + +G +D I+ W E V N + + + + +K+ V
Sbjct: 61 KVIEEAKALAEHGIVFGEPKTDIDKIR-TW---KEKVINQL--TGGLAGM-AKGRKVKVV 113
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLG 196
NGLG+F A+TL +NG K I N +IA G RP P IP S D L
Sbjct: 114 NGLGKFTGANTLEVEGENG-KTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELK 172
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQK-GV 254
P + LV+G G IGLE ++LG V+ + + D+ + + T + +K +
Sbjct: 173 EVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNL 232
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
+ K +VE E G + + + + +D VL+A GR K L+ AGV
Sbjct: 233 MLETKVT--AVEAKEDG-IYVTMEGKKAPAEPQR-YDAVLVAIGRVPNGKNLDAGKAGVE 288
Query: 315 CVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
V + G I + + +TNV +I+A+GD++ G+P L +H G +A + AG D
Sbjct: 289 -VDDRGFIRVDKQLRTNVPHIFAIGDIV-GQPMLAHKGVHEGH-VAAEVIAGKKHYFDPK 345
Query: 374 NVATTVFTPLEYGCVGLSEETA 395
+ + +T E VGL+E+ A
Sbjct: 346 VIPSIAYTEPEVAWVGLTEKEA 367
>UniRef50_Q9CH92 Cluster: Glutathione reductase; n=3; Lactococcus
lactis|Rep: Glutathione reductase - Lactococcus lactis
subsp. lactis (Streptococcus lactis)
Length = 435
Score = 123 bits (296), Expect = 1e-26
Identities = 124/438 (28%), Positives = 180/438 (41%), Gaps = 41/438 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D +IG G GGL A K+ +++ KWG GTC N GC P K+M
Sbjct: 2 FDYIIIGAGPGGLGLAYRLKTKDNKIGIIE-------NDKWG--GTCPNYGCDPTKMMMA 52
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+ + G + I+W L N T L+ I+ + G
Sbjct: 53 VVEAKSRVEQLKGQGIS----GELNIDWKGLKSRKLNITDPYEKSTFTGLKNAGIETIYG 108
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
F D L K AK +IA G RP DI G E+ +S+D +L P
Sbjct: 109 SAAFNDQGKL-----EVEGKTYQAKTYIIATGSRPRLLDIDGK-EFLKTSNDFLALEEFP 162
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGVVFHN 258
+ +G+G I LE A + G T++ R + FD++M Q + ++ +G+ F
Sbjct: 163 AQISFLGSGPISLELAQIAKAAGSDVTIISRKKARVAHFDEEMGQEFINYLKAQGIKFIE 222
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
VEK+ G L T+ + + D V+ GR + LNLE GV
Sbjct: 223 DISVDKVEKVADGFLLT--DGTDFEHK----TDLVIAGVGRQPNSDKLNLEKVGVE-TDA 275
Query: 319 SGKIIAETEQTNVSNIYAVGDVL-EGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
G + E QT+ S IYA+GDVL + +P LTPV+ G L + Q + Y + T
Sbjct: 276 KGIKVNEYLQTSNSKIYAMGDVLSKNQPHLTPVSSFEGAYLGENLVKDEPQKIAYPAIPT 335
Query: 378 TVFTPLEYGCVGLSEETALARHGA-DKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+F G L+E LA G K ++Y P ++ VAL E
Sbjct: 336 IIF-----GTAKLAEVGHLAGEGIHTKTLDLSSWYTYKRINDPLAKLK------VALNE- 383
Query: 437 PQRILGLHFVGPVAGEVI 454
+ I+G V VA EVI
Sbjct: 384 KREIVGASTVSSVADEVI 401
>UniRef50_Q8CQA3 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Staphylococcus|Rep: Dihydrolipoyl dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 469
Score = 123 bits (296), Expect = 1e-26
Identities = 124/442 (28%), Positives = 201/442 (45%), Gaps = 47/442 (10%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIG G GG A LG V V++ K GGTC+NVGCIP K + +
Sbjct: 24 YDLIVIGAGPGGYVAAIRGAQLGKNVAVIE---------KNNAGGTCLNVGCIPSKTLLE 74
Query: 80 AALLGESIHE-AVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
GE H VA W + + D +KI++ + + ++++ + L++ K+ Y+
Sbjct: 75 H---GEKAHSIRVANDWGITTKD-LKIDFTQFVQRKKKVVQTLTGGVKQLLKKNKVTYIE 130
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIFSLG 196
GE + + L + N + AK+I++A G +P P I G V Y ++D F L
Sbjct: 131 --GEARISKNLKVDVNN---ETYQAKDIILATGSQPFIPPIDGLDQVNY-ETTDTFFDLE 184
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P + V+G G I E A + LG T++ + D + + E
Sbjct: 185 KLPKQLAVIGGGVIATELASSMADLGVRVTIIEVA------DDILLTEINETREMLKAHL 238
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALT---KTLNLEAAG 312
N+ + + + K + Q+K ++ + +DV FDT+L+ATGR T K LNLE G
Sbjct: 239 DNQGIKI-LTKAKIKQVK---ESKIILDGQDDVSFDTLLVATGRQPNTQVAKDLNLEMDG 294
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
N E +T+ ++YA+GD+++G +L A G + + +
Sbjct: 295 KFFKVN------EHYETSQKHVYAIGDLIKGY-QLAHAASAHGIHVVETIMNKQPSLVRQ 347
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
+++ ++T LE VGLSE A G D AF + I N ++K V
Sbjct: 348 EDITRCIYTRLEAASVGLSEAQA-KEAGYDVKVTQSAFQGNAKALIKGEN--EGFIKLVV 404
Query: 433 LREAPQRILGLHFVGPVAGEVI 454
++ + +LG VGP A ++I
Sbjct: 405 DKKYGE-VLGAFIVGPHATDII 425
>UniRef50_Q24PW4 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Desulfitobacterium hafniense Y51|Rep: Dihydrolipoyl
dehydrogenase - Desulfitobacterium hafniense (strain
Y51)
Length = 461
Score = 123 bits (296), Expect = 1e-26
Identities = 105/377 (27%), Positives = 176/377 (46%), Gaps = 25/377 (6%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQAA 81
+AV+G G G A A LGA+V V++ + LGG C+N GCIP K + + A
Sbjct: 8 IAVLGSGPAGYVAAIRASQLGAEVVVIE---------EEDLGGVCLNRGCIPTKALLKTA 58
Query: 82 LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGLG 141
+ + +G E L+A NW + +K++N LR + I + G G
Sbjct: 59 EIAVMAKRSKEFGIE-SQLEAK--NWGVAVDRKNRIVKNLNSGLDNLLRARGITVLKGKG 115
Query: 142 E-FKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLGHPP 199
+ L+ T + E+ + +++ G P I G I+SD+ +L P
Sbjct: 116 TVLSERKILVQTTEEVI--EVNCEKMILTTGAVPLILPIKGIDSAGVITSDEALNLKALP 173
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFHN 258
+++GAG IGLE A L G T++ ++ L D+++A + M+++G++F
Sbjct: 174 ESIVIIGAGVIGLEFAAMLGHAGVKVTIIELQDRILPNEDREIAAELQKIMKRQGIIFKL 233
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+ K+E G L + E + R + VL+A GR T + E +T +
Sbjct: 234 SASVTEIHKIEDG-LIVTYSMGEKEFR--HPCEKVLVAAGR--KTNSDIFEKLPLT-IEK 287
Query: 319 SGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVATT 378
++ E +TNV +YA GD++ GK +L +A G++ A G T ++Y V T
Sbjct: 288 GAVVVDEFMETNVKGVYAAGDLVGGK-QLAHLAFMEGKVAAENAL-GITSKVNYSAVPTC 345
Query: 379 VFTPLEYGCVGLSEETA 395
++T E VG++EE A
Sbjct: 346 IYTNPEMASVGMTEEQA 362
>UniRef50_A6Q9K6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E3 component, dihydrolipoamide dehydrogenase;
n=1; Sulfurovum sp. NBC37-1|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E3 component, dihydrolipoamide
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 464
Score = 123 bits (296), Expect = 1e-26
Identities = 115/394 (29%), Positives = 180/394 (45%), Gaps = 29/394 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIG G GG A A G V ++D +P GG C+ GCIP K++
Sbjct: 4 YDLVVIGAGPGGTPAAMAAAQFGKSVLLVD-KRDAP-------GGECLFEGCIPSKVLEN 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIK--SVNWVTRVDLREKKIDYV 137
AA E E A+ +V + +I+W A+ E + +K S+ + +V+ R +++
Sbjct: 56 AANRFEIFKEMKAFHIDVDGKE--QIHWEAVLEDKKQILKRRSMGALKQVE-RFPNLEFR 112
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG-AVEYCISSDDIFSLG 196
G F D HT+ +G K I + +IA G P G V+ ++ ++F
Sbjct: 113 QGTARFTDTHTIDV---DGEK--IAFDHAIIATGAAAFLPPFEGKGVKNAWTNAEVFEKT 167
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVV 255
P + +GAG I E N LG +L R L+ D++ A V +M ++G+
Sbjct: 168 ELPEEITFIGAGAISCELVQMFNKLGTKCHMLERGERILKHIDEESAMVVQEKMIREGI- 226
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDT--VLMATGRYALTKTLNLEAAGV 313
+ + ++ K+E G+ + + + TQ+ V +T +L+ATGR A + L LE GV
Sbjct: 227 --DVQLNVTFGKIE-GE-EGAFSVSYTQDGEAKVLETPYLLIATGRAANVEGLGLETVGV 282
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
G + ET QT NIYAVGD G P+ A + + +FA D
Sbjct: 283 D-FDRHGIHVDETLQTTQENIYAVGDCTVG-PKFAHWATYEAGIAIHNIFAPMKHKTDMS 340
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVY 407
++ +F+ + VGLSE A + VE Y
Sbjct: 341 KLSWVLFSDPQIASVGLSEADAQKQGMEVSVERY 374
>UniRef50_A5KTA3 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; candidate
division TM7 genomosp. GTL1|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- candidate division TM7 genomosp. GTL1
Length = 426
Score = 123 bits (296), Expect = 1e-26
Identities = 117/406 (28%), Positives = 184/406 (45%), Gaps = 31/406 (7%)
Query: 63 GGTCVNVGCIPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVN 122
GGTC N GCIPKK++ AA + + G ++ + ++++W L V+
Sbjct: 20 GGTCDNRGCIPKKILVGAAKVADLNRRF--QGLDIVT-KPVELSWEGLMNFKSTFTSPVS 76
Query: 123 WVTRVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA 182
T+ L + + G +F + TL NG +++TA++ IA G +P + GA
Sbjct: 77 EETKEPLEKAGVKLYEGSPKFVNEDTLEV---NG--EQLTAEHFHIATGAKPAKLSVEGA 131
Query: 183 VEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQM 241
E+ +SDD SL P + + VG GY+ E A G T+L PL FD
Sbjct: 132 -EHLKTSDDFLSLTSLPKRIIFVGGGYVSFELAHVAARFGAKVTILHNDDRPLAAFDPDT 190
Query: 242 AQAVTSEMEQKGVVFHNKCVPLSVEKL-ETGQLKARWQNTETQERGEDVFDTVLMA--TG 298
+ + + ++ GV + + EK+ +TG+ T G + V+ G
Sbjct: 191 VKTLIAASKEAGV---EVVLNAAAEKITKTGE-------GVTVHAGNKEYAVVMAVHGAG 240
Query: 299 RYALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSN--IYAVGDVLEGKPELTPVAIHAGR 356
R TL+LEAA V G ++ E Q +VSN +YA GD P L+P+A G
Sbjct: 241 RPPAIDTLDLEAANVQS-ERRGVMVNEYLQ-SVSNPRVYAGGDAAAAGPPLSPIARLHGS 298
Query: 357 LLARRMFAGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEF 416
++A + T+ DY + + VFT VGL+E+ A+ G D H T F
Sbjct: 299 IVADNLLGIKTKQPDYRSTPSVVFTEPPLAMVGLTEQ-AVKEKGID--ATVHTENMSTWF 355
Query: 417 FIPQRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ N+ + K + + RILG H VG A ++I FA A++
Sbjct: 356 DAKRTNLTHTMAKTLVDAQT-NRILGAHIVGNHAEDLINMFALAIE 400
>UniRef50_Q97C54 Cluster: Mercuric reductase; n=2; Thermoplasma|Rep:
Mercuric reductase - Thermoplasma volcanium
Length = 471
Score = 123 bits (296), Expect = 1e-26
Identities = 107/384 (27%), Positives = 174/384 (45%), Gaps = 30/384 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL ++G G+ + A A + + + V P LGGTCVN GC+P KL+
Sbjct: 6 YDLVIVGRGAAAFSAAIRASEITSGQARIAMVGNGP------LGGTCVNTGCVPSKLLIS 59
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIK-SVNWVTRVDLRE-----KK 133
+ S ++ + P L +++ P TE + + I+ SV+ + + +
Sbjct: 60 ---ISNSFQNSLKPRY--PGLPSVER--PPETEVIMDFIRESVHGERKKKYEDVVESYEN 112
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYC-ISSDDI 192
ID G F ++ S + N++IA G RP+ P I G E I++D +
Sbjct: 113 IDLYTGTAVFTGEKEILVD----SSHSLFGYNVLIATGSRPYVPGIKGLNETSYITTDSV 168
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQ 251
+ L H P ++G G +G+E L+ LG ++ V + L G MA + + +
Sbjct: 169 WELKHVPASIAILGGGAVGVEIGQALSRLGSEVHIIEVSNQILPGIPADMASIIERSLRE 228
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
G+V + SV+++ G+ K + T + +L+ATGR A L LE
Sbjct: 229 DGMVINTST---SVDEVSGGEGKKYLKLNGTNINDTLEVEEILVATGR-APNIDLALEKT 284
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
GV S G + E +T+ IYA GDV++ K +L +A G + A MF A + +D
Sbjct: 285 GVK-YSKRGIAVDEYLRTSNRKIYAAGDVVDQKYKLETLAAREGFISAENMFNHAMRTID 343
Query: 372 YDNVATTVFTPLEYGCVGLSEETA 395
NV VF Y VG +++ A
Sbjct: 344 IFNVPFAVFCSPGYASVGYTQDEA 367
>UniRef50_Q8F290 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Leptospira|Rep: Dihydrolipoyl dehydrogenase - Leptospira
interrogans
Length = 490
Score = 122 bits (295), Expect = 2e-26
Identities = 111/387 (28%), Positives = 180/387 (46%), Gaps = 29/387 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDL VIG G GG A A LG V +++ P GG C+N GCIP K + +
Sbjct: 23 YDLTVIGAGPGGYVAAIRAAQLGMNVCIIEKDKP---------GGICLNWGCIPTKALLE 73
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A L E +H A YG +L K ++ A+ +N + L + KI G
Sbjct: 74 SAHLLEKLHSAKEYG---INLSDPKPDFAAIIRRSRNVADGMASGVEFLLNKNKITRKKG 130
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGHP 198
FKD +T+ L + SK+EIT+K ++A G R P +P +SS
Sbjct: 131 TAVFKDPNTI--WLPDSSKEEITSKYFILATGARARELPGLPFDSHTVLSSKTAMIQDKI 188
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P L+VGAG IG+E A F +++G T++ + L D++++ + ++G+
Sbjct: 189 PESLLIVGAGAIGVEFADFYSTMGTKVTLVEMMDQILPVEDKEISTFLEKSFVKRGIRVL 248
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVTCV 316
V +S K+ G++K + E E + +L++ G T +++LE G+
Sbjct: 249 TG-VGVSDPKIVNGKVKVLLKGKNLPEAVESFEAEKILVSIGLVPNTDSMHLEEIGI--F 305
Query: 317 SNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAG--RLLARRMFAGATQ----- 368
G + +T+ +T+V +IYA+GD G P L VA G + A + AG
Sbjct: 306 LQKGFVKTDTKYKTSVPHIYAIGD-CNGPPLLAHVASMEGIKAVEAISIHAGNPHHLSYI 364
Query: 369 PMDYDNVATTVFTPLEYGCVGLSEETA 395
P+DY+ + + E +G +E+ A
Sbjct: 365 PIDYNAIPGCTYCHPEVASIGFTEKKA 391
>UniRef50_P50970 Cluster: Dihydrolipoyl dehydrogenase; n=25;
Proteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Zymomonas mobilis
Length = 466
Score = 122 bits (295), Expect = 2e-26
Identities = 119/450 (26%), Positives = 204/450 (45%), Gaps = 35/450 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL V+GGG GG A A L KV +++ V LGG C+N GCIP K + +
Sbjct: 5 FDLIVLGGGPGGYVAAIRAAQLNLKVALVERVH---------LGGICLNWGCIPTKSLLR 55
Query: 80 AALLGESIHEAVAYGWEV--PSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
+A + + A AYG P D KI A + V + S + LR+ K++ +
Sbjct: 56 SAEVYHEMQNAEAYGLTSFKPDFDLDKII--ARSREVATRLASG---VKTLLRKNKVEVI 110
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLG 196
+G+G+ ++ G +K + AK+I+IA G R P++ ++ +
Sbjct: 111 SGVGQLTGNQQMLVETTEGEEKILEAKDIIIATGARARQLPNVHSDGKHIWTYHHALKPP 170
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKGVV 255
P K LV+G+G IG+E A F G +++ + + D +++ V +++G+
Sbjct: 171 AMPKKLLVIGSGAIGIEFASFYADFGAEVSIVEHAPQILPMEDAEVSAYVAKAFKKRGIR 230
Query: 256 FHNKCVPLSVEKLETGQLK--ARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ ++ + G A T+ER F ++A G A + + L+ G+
Sbjct: 231 ILTQSALQNLTPDDEGVTAEIAGADGKVTKER----FSHAIVAIGVVANVENIGLDKLGI 286
Query: 314 TCVSNSGKIIAE-TEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGA--TQPM 370
+ G I + +TNV +++A+GDV G P L A H G ++A AG P+
Sbjct: 287 KL--DRGFIAVDGFGRTNVDHVWAIGDV-AGAPCLAHKASHQG-VIAAEAIAGCDHVHPL 342
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
+ N+ + + VGL+EE AR V++ + + I Q + ++K
Sbjct: 343 NTQNIPGCTYARPQVASVGLTEEK--ARQQGYNVKIGNFPFIANGKAIAQ-GATDGFVKT 399
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAA 460
V ++ +LG H VG E+IQG+ A
Sbjct: 400 VFDADS-GALLGAHMVGAEVTEMIQGYTVA 428
>UniRef50_Q9I1L9 Cluster: Dihydrolipoyl dehydrogenase; n=54;
Proteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Pseudomonas aeruginosa
Length = 464
Score = 122 bits (295), Expect = 2e-26
Identities = 125/451 (27%), Positives = 208/451 (46%), Gaps = 41/451 (9%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMHQA 80
L ++GGG GG A A LG +++ LGGTC+NVGCIP K L+H A
Sbjct: 9 LLIVGGGPGGYVAAIRAGQLGIPTVLVEGAA---------LGGTCLNVGCIPSKALIHAA 59
Query: 81 ALLGESIHEA--VAYGWEV--PSLD-AIKINW-PALTEAVQNHIKSVNWVTRVDLREKKI 134
++ H A A G +V PS+D A + W A+ + + + + ++ L++ +
Sbjct: 60 EEYLKARHYASRSALGIQVQAPSIDIARTVEWKDAIVDRLTSGVAAL-------LKKHGV 112
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIF 193
D V G D ++ L G + I +++++A G + P +P + ISS +
Sbjct: 113 DVVQGWARILDGKSVAVELAGGGSQRIECEHLLLAAGSQSVELPILPLGGK-VISSTEAL 171
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQ 251
+ G P + +VVG GYIGLE LG V V + P L G+D+++ + V + +
Sbjct: 172 APGSLPKRLVVVGGGYIGLELGTAYRKLGVEVAV-VEAQPRILPGYDEELTKPVAQALRR 230
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
GV + L L + R ++ +ER E D VL+A GR ++ NLE+
Sbjct: 231 LGVELY-----LGHSLLGPSENGVRVRDGAGEER-EIAADQVLVAVGRKPRSEGWNLESL 284
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
G+ + K+ + +T++ N++A+GD L G+P L A+ G ++A + AG +
Sbjct: 285 GLDMNGRAVKVDDQC-RTSMRNVWAIGD-LAGEPMLAHRAMAQGEMVA-ELIAGKRRQFA 341
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAV 431
+ FT E GLS E A G D + F + N +++ V
Sbjct: 342 PVAIPAVCFTDPEVVVAGLSPEQA-KDAGLDCLVASFPFAANGRAMTLEAN--EGFVRVV 398
Query: 432 ALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
A R+ ++G VG E+ FA +++
Sbjct: 399 ARRD-NHLVVGWQAVGKAVSELSTAFAQSLE 428
>UniRef50_Q8CU56 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Bacillales|Rep: Dihydrolipoyl dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 504
Score = 122 bits (294), Expect = 2e-26
Identities = 116/448 (25%), Positives = 198/448 (44%), Gaps = 31/448 (6%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
DL VIG GSGG A A LG KV ++D K LGG C+N GCIP K + A
Sbjct: 41 DLLVIGAGSGGYVAAIRAAQLGKKVVLVD---------KAELGGVCLNRGCIPSKALISA 91
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
+ + I A G +V ++++ P + + + + R L+ ++ ++G
Sbjct: 92 SERVKHIKHANTMGLKVSG--EVQVDMPEVVKWKDGIVNKLTDGIRTLLKGNGVEVISGE 149
Query: 141 GEFKDAHTLIATLKNGSKKEI-TAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGHP 198
+AH IA +K +++I + K++++A+G P +P + ISS + L
Sbjct: 150 AYLTEAH--IAKIKIEDEEQIFSYKDLILAIGSLPVELKSMPFDQKRIISSTEALQLQEV 207
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRS-VPLRGFDQQMAQAVTSEMEQKGVVFH 257
P +VVG GYIGLE G T+L S L G D + + V +++ G+
Sbjct: 208 PNHLVVVGGGYIGLELGTAYAKFGAKVTILEGSDTILSGTDPILTKTVKRHLKEIGITV- 266
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVF---DTVLMATGRYALTKTLNLEAAGVT 314
++ ++ G+ N Q G++ D L++ GR T + LE GV
Sbjct: 267 -----ITDALVQGGENTGDEVNVHVQVDGKEEIIQCDYCLVSIGRKPNTGKIGLENIGVV 321
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
I QTN+ ++YA+GD G L A + + +A + +G +D+
Sbjct: 322 LDDQGFIKINNKCQTNIEHVYAIGD-CAGGDLLAHKASYEAK-IAAEVISGQNSVIDFQA 379
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
+ +F+ E GL+E+ A + G + V F + + +++ VA +
Sbjct: 380 MPFVIFSDPEVAYTGLTEKEAKEK-GYETVSSRFPFQANARAL--SVSDADGFVQVVAEK 436
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+R+LG+ VGP +I A++
Sbjct: 437 NT-KRVLGVQMVGPEVSSLIAEAVFAIE 463
>UniRef50_P35484 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Acholeplasmataceae|Rep: Dihydrolipoyl dehydrogenase -
Acholeplasma laidlawii
Length = 336
Score = 122 bits (294), Expect = 2e-26
Identities = 97/360 (26%), Positives = 168/360 (46%), Gaps = 33/360 (9%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+Y++ ++GGG GG A +A GAKV +++ K +GG C+N GCIP K
Sbjct: 4 EYEIIIVGGGPGGYVAAIKAAQYGAKVALVE---------KEVVGGICLNHGCIPTKTFL 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
++A + ++ +++ +G V + + +W + +K + L++ +D N
Sbjct: 55 KSAKVFNTVKKSMDFG--VSTSGEVGFDWSKIVSRKDGVVKQLTNGVAFLLKKNGVDVYN 112
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE-----YCISSDDIF 193
G G+ K A+ ++ NG + + KN++IA G P IPG E ++S ++
Sbjct: 113 GFGDIKSANEVVV---NG--ESLKTKNVIIATGSSAVVPPIPGVKEAYEKGIVVTSRELL 167
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQK 252
++ + P ++VG G IG+E A NS G T++ + L D + A +++
Sbjct: 168 NVKNYPKSIVIVGGGVIGVEFATVFNSFGSKVTIIEMMDGILPTMDDDIRVAYAKTLKRD 227
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
G+ K V+K++ ++ ET G D +LM+ G A +K LE G
Sbjct: 228 GIEILTKA---EVKKVDDHKVTYSLDGKETTIEG----DLILMSVGTRANSK--GLEHLG 278
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
+ + + E QTNV +YA+GDV GK L VA H G + + M+Y
Sbjct: 279 LE-MDRANIKTNEYLQTNVPGVYAIGDV-NGKFMLAHVAEHEGITAVQHILKIGHAKMNY 336
>UniRef50_UPI0000ECC431 Cluster: Glutathione reductase,
mitochondrial precursor (EC 1.8.1.7) (GR) (GRase).; n=1;
Gallus gallus|Rep: Glutathione reductase, mitochondrial
precursor (EC 1.8.1.7) (GR) (GRase). - Gallus gallus
Length = 376
Score = 122 bits (293), Expect = 3e-26
Identities = 88/253 (34%), Positives = 134/253 (52%), Gaps = 19/253 (7%)
Query: 67 VNVGCIPKKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTR 126
VNVGC+PKK+M A+ E IH+ YG+E+P ++ NW + E +++ +N +
Sbjct: 1 VNVGCVPKKVMWNTAVHAEFIHDHPDYGFEIPG---VRFNWRTIKEKRDAYVRRLNEIYE 57
Query: 127 VDLREKKIDYVNGLGEFK-DAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP---DIPGA 182
++ + ID + G G+F D I +G K TA +I+IA GGRP P ++PGA
Sbjct: 58 NNVAKAHIDIIRGYGKFTADPEPTIEV--DGQK--YTAPHILIATGGRPVVPPDCEVPGA 113
Query: 183 VEYCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV-RSVPLRGFDQQM 241
I+SD F L P ++VVGAGYI +E G L++LG +++L+ R LR FD +
Sbjct: 114 -SLGITSDGFFDLEELPRHSVVVGAGYIAVEIVGILSTLGSKSSLLIRRDKVLRTFDSLI 172
Query: 242 AQAVTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTE-----TQERGEDVFDTVLMA 296
+ T E+E GV +V K +G L+ ++E T + DV D +L A
Sbjct: 173 STNCTQELENMGVDVWKHTQVQAVTKSPSGLLEVTVTSSEPGHKPTVKVIRDV-DCLLWA 231
Query: 297 TGRYALTKTLNLE 309
GR T+ L L+
Sbjct: 232 IGRKPNTEELCLD 244
>UniRef50_A7HHC7 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Anaeromyxobacter|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Anaeromyxobacter
sp. Fw109-5
Length = 481
Score = 122 bits (293), Expect = 3e-26
Identities = 120/444 (27%), Positives = 183/444 (41%), Gaps = 23/444 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ VIG G G A +A G KV +++ GG N G IP K + +
Sbjct: 4 YDVVVIGSGPAGENGAIQAAFTGKKVALIEKEAVP--------GGASANTGTIPSKALRE 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AL A+G E+ + I P L + R L ++ G
Sbjct: 56 TALAILQARSRDAHGIELRISGTVTI--PELMGRKGLVTAREHSRIRDALNRAGVEQFRG 113
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGHP 198
+ F D HT+ ++ +G +E+ A I++A G RP H P P + SD I L
Sbjct: 114 IASFVDPHTIRVSIPDGGAQELQADIILLAPGTRPFHPPQYPIDNAHVYDSDSILLLDRV 173
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P V+G G G E A +LG ++ + L D +M+ A+ G+ H
Sbjct: 174 PRSLAVLGGGVAGCEYASLFGALGVNVKLVDSKDRLLTWLDAEMSHALEDVFRSSGIDLH 233
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
+ +L+ G ++ G V VL+A+GR + LNL AAG+
Sbjct: 234 QRN---RAARLDPGDKDVL---VTLEDGGRMVAQKVLVASGRVGNVEALNLPAAGLEATE 287
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
+ QT V +IYA GDV+ G P L V++ GR+ G + +
Sbjct: 288 RGLLKVNAQFQTAVPHIYAAGDVV-GFPGLASVSMEQGRVAMSHACGGILKQRVSSILPM 346
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAP 437
++T E VG +EET L G V + + + + +LK +A E
Sbjct: 347 GIYTIPEVSSVGDTEET-LKEQGRAYVVGRASLTENARANLIGEAVG--FLKIIADAE-N 402
Query: 438 QRILGLHFVGPVAGEVIQGFAAAV 461
RILG+H +GP A E++ AA +
Sbjct: 403 GRILGVHCIGPHASELVHTGAAVM 426
>UniRef50_Q8KB36 Cluster: Dihydrolipoamide dehydrogenase; n=2;
Chlorobaculum tepidum|Rep: Dihydrolipoamide
dehydrogenase - Chlorobium tepidum
Length = 467
Score = 121 bits (292), Expect = 4e-26
Identities = 110/431 (25%), Positives = 192/431 (44%), Gaps = 25/431 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+ +IGGG GG A + + G V +++ + K LGG C+ VGCIP K++
Sbjct: 5 FDVIIIGGGPGGTPAAMQLASQGKTVLLVE------ESGK--LGGACLFVGCIPSKIIRH 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLRE-KKIDYVN 138
A E + E S + + W + +Q + + L+ + +V
Sbjct: 57 WA--DEYAVKLKYSAQEALSPEDREAAWNEIMRKMQTILSQRSGAAMQMLKHLSNLRFVA 114
Query: 139 GLGEFKDAHTLIATLKN-GSKKEITAKNIVIAVGGRPHYPDIPG-AVEYCISSDDIFSLG 196
G +F + L+ K+ G K++ T +IA G P G V+ ++S+ +FS
Sbjct: 115 GHAKFVSNNELVINEKDTGRKEKYTFNKAIIATGSHSFIPPFKGNGVQDVLTSEVLFSQD 174
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATV--LVRSVPLRGFDQQMAQAVTSEMEQKGV 254
P L++G G IG+E A L LG T+ L+ S+ + + +++++ GV
Sbjct: 175 KLPESLLIIGGGPIGIELAQMLTKLGTKCTIIELLDSILYGVVETEFVSIISNQLSSLGV 234
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
+ + K + G + + E E+ F+ VL+ TG+ ++LNL++ +
Sbjct: 235 NIYTSSQVQEINKSD-GHFDVTFTDANGSEHKEN-FEDVLVVTGKVPNIESLNLDSTDIK 292
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
G I+ E +T+V IYA GDV G P+ A + + + + AG Q +D+
Sbjct: 293 -YDRKGIIVDEYLETSVKGIYATGDVTHG-PKFAHTATYEAHIASANISAGNNQKVDFSK 350
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVE-VYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+F+ E G +E A+ + G D + VY YK + N YLK V +
Sbjct: 351 NTWVLFSEPEIVAAGFTEAQAV-QEGYDIITGVYD--YK-IDAAAQVMNSPFGYLKYV-V 405
Query: 434 REAPQRILGLH 444
+ I+G+H
Sbjct: 406 NKKNSEIIGVH 416
>UniRef50_Q1IMV9 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Bacteria|Rep: Dihydrolipoyl dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 474
Score = 121 bits (292), Expect = 4e-26
Identities = 119/446 (26%), Positives = 199/446 (44%), Gaps = 25/446 (5%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMHQ 79
++AVIGGG GG A A A +LG VT++D + +P GG C+ GCIP K L+H
Sbjct: 8 NIAVIGGGPGGYAAAFLAADLGMTVTLID-MELNP-------GGVCLYRGCIPSKALLHV 59
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A L+ E+ H W V + DA KI+ L + +K + +++K+ Y+ G
Sbjct: 60 AKLIEEAKHST---NWGV-TYDAPKIDLERLRTFKEGVVKKLTGGLGQLSKQRKVTYIQG 115
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHY-PDIPGAVEYCISSDDIFSLGHP 198
D+ T+ G ++ + +++A G RP P + S +L
Sbjct: 116 KATLVDSCTVKVEKTAGGEETLHFDKLILATGSRPAVIPAFNIGSPRVMDSTGALNLEDI 175
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLR-GFDQQMAQAVTSEMEQKGVVFH 257
P + LVVG GYIGLE ++G +V+ + L G D+ + + +
Sbjct: 176 PKRLLVVGGGYIGLELGSVYAAIGSKVSVVEMTAGLLPGADRDLVAPLHKRLTGIFEAIM 235
Query: 258 NKCVPLSVEKLETGQ-LKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
+S+ +TG +K +++ + +E E +D VL++ GR ++ L+ V
Sbjct: 236 LNTTVISIA--DTGSAVKVKFKTQDGKEE-EQTYDRVLVSVGRKPNSQIPGLDKTRVKVN 292
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ + T+ IYA+GDV+ G+P L A H G L+A AG + +
Sbjct: 293 QKGFLQVNPSLMTDDPFIYAIGDVV-GEPMLAHKASHEG-LVAVESIAGHKVAFEPQAIP 350
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
VFT E GL+E A ++ +V V + + + L + +
Sbjct: 351 AVVFTDPEIAWAGLTETQA--QNEGREVTVTKFPWAASGRAVTIDRTEG--LTKLIIDPQ 406
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
+R+LG+ GP AGE+I A++
Sbjct: 407 TERVLGVGICGPGAGEMIAEGVVAIE 432
>UniRef50_Q41CB3 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase:Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
precursor; n=1; Exiguobacterium sibiricum 255-15|Rep:
FAD-dependent pyridine nucleotide-disulphide
oxidoreductase:Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor -
Exiguobacterium sibiricum 255-15
Length = 475
Score = 121 bits (291), Expect = 5e-26
Identities = 117/439 (26%), Positives = 197/439 (44%), Gaps = 30/439 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
Y L VIGGG+ G+ A A +LGA V +++ T LGG C++ GC+P K + +
Sbjct: 4 YQLVVIGGGAAGMTIAAGAASLGAHVALIEKHT--------HLGGDCLHYGCVPSKALIE 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA + + A + +A+ A + +N I+S + R ++ +D G
Sbjct: 56 AAHDVHVMKQTAAKYNVTLNGEAVYSKTKASVDRARNIIQSHDGTKR--FKDLGVDVYIG 113
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIFSLGH 197
F A+ + + + + + I+ G +P P I G + Y ++++ IF
Sbjct: 114 EASFLSANEV-----EVAGQLVVGEKFAISTGSQPIIPPIEGLDTIPY-LTNETIFEQTE 167
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLR-GFDQQMAQAVTSEMEQKGVVF 256
P + LV+G G IGLE + LG TV+ + L D+ M + + ++EQ+ +
Sbjct: 168 RPERLLVIGGGAIGLELSQAYAHLGTEVTVIEGAKSLMPKEDRSMVEVLQRQIEQE-LTL 226
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
H SV K G ++ + E E D VL+A GR L L+ AGV V
Sbjct: 227 HLDTTVTSVRKAAKG-IEVTVKTGEESRVIET--DAVLVAVGRKPRIDALRLDRAGVH-V 282
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+ + +TN +I+AVGD ++ P + ++ +F T+P DY V
Sbjct: 283 EKGYVQVDGSLRTNQRHIFAVGDTIQSLPFTHVAGLEGKTVVTNALFGLRTKP-DYRAVP 341
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
FT E +GL+EE AR ++VY + F+ ++K +A +
Sbjct: 342 WVTFTTPELFHLGLTEEE--ARQKYSDIKVYETGLDEVDRFVINGRTEG-HVKLIADKRG 398
Query: 437 PQRILGLHFVGPVAGEVIQ 455
+++G H +G AGE +Q
Sbjct: 399 --KLIGAHAIGEQAGEWMQ 415
>UniRef50_Q8PS09 Cluster: Dihydrolipoamide dehydrogenase; n=5;
Euryarchaeota|Rep: Dihydrolipoamide dehydrogenase -
Methanosarcina mazei (Methanosarcina frisia)
Length = 487
Score = 121 bits (291), Expect = 5e-26
Identities = 118/441 (26%), Positives = 194/441 (43%), Gaps = 27/441 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAV--NLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
DYDL VIG GSG + + N K+ V+D P GG C+ GCIP KL
Sbjct: 8 DYDLIVIGTGSG-MNYVNSIIDSNPKMKIAVIDKDEP---------GGICLTRGCIPSKL 57
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK-ID 135
+ A L + A +G ++ D I + + E ++ I + R L E +D
Sbjct: 58 LLYPAELVRDLETAPLFGIKLEIKD---IEFRTIMERMRKRIGEDIEMIRQGLTENDYLD 114
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFS 194
Y EF +TL A + + ++ I + G +P P + G E ++SD +
Sbjct: 115 YYPETAEFISPYTLKA-----GDEILHSEMIFLCTGSKPAVPPVRGLEEAGYLTSDTVLG 169
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKG 253
L P ++G YIG E F +++G TV+ R+ L + ++++ +M +
Sbjct: 170 LNECPKSLAILGGSYIGAEYGHFFSAMGAEVTVIGRNQHFLPQEEPEVSELARIKMSEYM 229
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ N + V K + GQ ++ ++ E E D +L+ATGR L+ E AG+
Sbjct: 230 RILTNH-EAIEVRKEKGGQKTVIAKDRDSGEETEVTADEILVATGRAPNNDILHPEKAGI 288
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ ++ E +T+ NI+A GD GK L V + ++ +DY
Sbjct: 289 KTDPHGWILVNEYLETSQPNIWAFGDA-NGKYLLKHVGNYESGIVYLNAIMQEKVKVDYH 347
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
V VF+ E VG+SE+ A+ G +V + ++ T R+ ++K V L
Sbjct: 348 AVPHAVFSYPEIAGVGMSEKEAIEEFGEKRVIIGFKLFEDTAKGSAMET-RDYFVK-VIL 405
Query: 434 REAPQRILGLHFVGPVAGEVI 454
+ILG H +GP A +I
Sbjct: 406 DGLEDKILGAHIIGPHASVLI 426
>UniRef50_A4CGZ8 Cluster: Regulatory protein; n=5;
Flavobacteriaceae|Rep: Regulatory protein -
Robiginitalea biformata HTCC2501
Length = 448
Score = 120 bits (290), Expect = 6e-26
Identities = 122/449 (27%), Positives = 189/449 (42%), Gaps = 36/449 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ +IG G G+ A + + G V + D + GGTC GC PKK+
Sbjct: 4 YDVFIIGSGMSGMTIAYKCASKGLSVGITDELP---------YGGTCALRGCDPKKV--- 51
Query: 80 AALLGESIHEAVAYGWEVPSLDAIK-INWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
++G + A + +D I INW + Q + + ++ ID +
Sbjct: 52 --IIGATEVRDFAKRLQGKGIDTIPDINWKDIMAFKQTFVDEMPRKIEKGYKKNGIDTFH 109
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
F + +TL + I A N+VIA G +P D G + +S D +L
Sbjct: 110 SSAAFINENTLSV-----GNQTIQADNVVIASGSKPKVLDFEGG-QLAQTSTDFLNLKEL 163
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFH 257
P L +G GYI E A G T++ R PL FD+ + + + GV
Sbjct: 164 PESLLFIGGGYIAFEFAHIAARSGAEVTIVHRGKRPLENFDKDIVKHLVDATINLGV--- 220
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDT--VLMATGRYALTKTLNLEAAGVTC 315
+ V K+E+ + T E E + + V + GR L LE AG++
Sbjct: 221 RLVLETEVSKIESED--GHFVTTGISEGMETTYKSKAVFNSAGRPPAIFDLELEKAGIS- 277
Query: 316 VSNSGKIIAETEQT-NVSNIYAVGDVLEGKP-ELTPVAIHAGRLLARRMFAGATQPMDYD 373
S G + E Q+ + +NIYA GD + + LTPVA+ G ++A + G + + Y
Sbjct: 278 FSKKGIAVNEYLQSISNANIYAAGDAADSRGLPLTPVAVLEGHVVASNIIKGNKKKVSYP 337
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ + VFT VGL E+ A + G D + F K +F +R + Y +
Sbjct: 338 PMPSVVFTLPTMATVGLLEDKAKEK-GFD---INVNFEKVGNWFNARRLNVDEYAFKTII 393
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ ILG H +GP E I FA A+K
Sbjct: 394 DKNSNTILGAHLIGPHCEETINLFAMAIK 422
>UniRef50_A0SNY8 Cluster: Mercuric reductase; n=1; uncultured
euryarchaeote ARMAN-2|Rep: Mercuric reductase -
uncultured euryarchaeote ARMAN-2
Length = 471
Score = 120 bits (290), Expect = 6e-26
Identities = 122/448 (27%), Positives = 192/448 (42%), Gaps = 26/448 (5%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D +IG GS + A +A LG ++ + G LGGTC+NVGC+P K M
Sbjct: 4 FDYVIIGQGSAAFSAAIKANELGKNTLMIG--KNATAGAV--LGGTCINVGCVPSKRMIS 59
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDL--REKKIDYV 137
A + + +G + D + + + E +K+++ D+ + + Y+
Sbjct: 60 VARFFKEL-SLKRFGGI--NYDLGSLEYERVVEEKDELLKTLHKSKYEDVIGSMENVHYL 116
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISSDDIFSL 195
N G F T ++K G KKEI A ++IA G R P I G ++Y + ++ +L
Sbjct: 117 NEFGSF----TSRTSIKAG-KKEIEADRVLIATGARAFIPKIEGIEKIDY-LDNEKALAL 170
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGV 254
P +VVG +GLE A + G TVL RS L ++ +A+ + + + G+
Sbjct: 171 KGLPRSIIVVGGRAVGLEFAQMFSMFGSKVTVLQRSPTILPNWEPVIAKRLEKYLIEDGI 230
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
P K E G++ + + + +LMATGR T L+LE A V
Sbjct: 231 DVITNAAPKKFYKSE-GKIMVDVELDGNVKTFSA--EKLLMATGRAPNTDMLDLEKASVE 287
Query: 315 CVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDN 374
N I T +T + I+A GDV G P L +A G L + F G ++ +
Sbjct: 288 TYGNGFVKIDNTMRTGSTGIFAAGDV-TGSPMLETLAAKEGNLATQNAFGGGKLKININE 346
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V + VFT E VG +EE ++ V A+ I L V +
Sbjct: 347 VPSAVFTEPEAAMVGKTEEQVISDLKNCGCNVLPAYAIAKANIISDTR----GLIKVVIN 402
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
ILG+H + A ++I AVK
Sbjct: 403 PKTHEILGVHMLAHGAADLIHEGVMAVK 430
>UniRef50_UPI00015BC7B4 Cluster: UPI00015BC7B4 related cluster; n=1;
unknown|Rep: UPI00015BC7B4 UniRef100 entry - unknown
Length = 481
Score = 120 bits (289), Expect = 8e-26
Identities = 122/451 (27%), Positives = 204/451 (45%), Gaps = 37/451 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+ ++GGGS A A +A ++GA+V V + +GGTC+N GCIP K + +
Sbjct: 19 HDIFILGGGSAAFAAAIKASDIGARVLVAENNI---------IGGTCLNRGCIPSKYLIE 69
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREK--KIDYV 137
A + + G E+ + + +N + E + +K + ++ E +I+Y
Sbjct: 70 VANTFYTPNRNPFPGVELATGN---LNIRNIIEKKEELLKELRKEKYWNVLEAYPQIEYR 126
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISSDDIFSL 195
N G+F D T + + +++ +IA G +P P I G V Y +SD+IF++
Sbjct: 127 NLRGKFVDEGTALV-----GEDKVSFYKAIIATGSKPLIPSIKGIEKVRY-YTSDNIFNI 180
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSE-MEQKGV 254
H P +++G G IGLE G T++ + + + E +E++G+
Sbjct: 181 DHLPKHLIIIGGGAIGLELGQAFLRFGSKVTIVEYFQEIAMAQEPEIRTKLKEVLEKEGI 240
Query: 255 VFHNKCVPLSVEKLETGQ--LKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
++ + E GQ L+ + + +T G D+ L+ATGR TK + LEA
Sbjct: 241 SILTNAEITNIWE-EDGQITLELKHEENKTTIHGTDL----LIATGREPNTKDIGLEATS 295
Query: 313 VTCVSNSGKIIA-ETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
V S G I A E QT NIYA GD + GK L VA G + A G + D
Sbjct: 296 VM-TSTRGFIQANEFMQTTNENIYAAGDCV-GKMMLVTVAAMEGGIAAENALLGNKKKAD 353
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAV 431
Y +V +FT E VG+ E A + +V P +++ L +
Sbjct: 354 YLSVPNAIFTYPEVARVGMGELEARKQGLEVEVRTLDLSKVPRAAL----SLQTEGLIKM 409
Query: 432 ALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ + ++I+G+H + P EVI ++K
Sbjct: 410 IVEKNTRKIIGVHILAPHGAEVIHKAVLSIK 440
>UniRef50_Q9RKH2 Cluster: Putative oxidoreductase; n=1; Streptomyces
coelicolor|Rep: Putative oxidoreductase - Streptomyces
coelicolor
Length = 505
Score = 120 bits (289), Expect = 8e-26
Identities = 128/450 (28%), Positives = 200/450 (44%), Gaps = 44/450 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
YDL VIGGGS GL A+ A LGA+ +++ + LGG C+ GC+P K L+H
Sbjct: 40 YDLVVIGGGSAGLTAARTAGRLGARTLLVE---------RDRLGGDCLWTGCVPSKALLH 90
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD-LREKKIDYV 137
AA + ++ A AYG +P + AL E V+ I ++ + L +D
Sbjct: 91 VAADV-QAARRATAYG--LPPVTGPADLTAALAE-VKRAIGAIEPHDSAEALAPYGVDVT 146
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLG 196
+G F TL A ++E++ + +IA G P IPG VE ++SD ++ L
Sbjct: 147 HGAASFTGPGTLTA-----GEREVSFRYALIATGSSPALVPIPGLVESGPLTSDTVWELS 201
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEMEQKG 253
P +V+G G IG E LG T+ + R VP + + +Q + ++ +G
Sbjct: 202 ELPHLLVVLGGGPIGCELGQAFARLGSQVTLVEAMDRLVPRE--EPRASQVLRERLQSEG 259
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
V E+++ + G +D +L TGR + T L LEAAGV
Sbjct: 260 VTV---LTDYRAERVDADAVHG--------PGGPLPYDALLAVTGRRSHTHGLGLEAAGV 308
Query: 314 TCVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
++++G I + +T IYA GDV G+ T + G A G +P+DY
Sbjct: 309 E-LTDAGHIRTDGRLRTTNHRIYAAGDV-TGRSAFTHLGGTQGGAAAVDALLGVRRPIDY 366
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
+T E VGL+ + A A++G D+ V+ + + +
Sbjct: 367 RAAPRVTYTDPEIAGVGLTLDEAHAKYG-DRARVHTLENDRVDRAVADGRTEGFTTLVLG 425
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
R +I+G V P AGE + AAAV+
Sbjct: 426 PR---GKIVGATVVSPRAGETVAHLAAAVR 452
>UniRef50_Q8F4C6 Cluster: Dihydrolipoamide dehydrogenase; n=4;
Leptospira|Rep: Dihydrolipoamide dehydrogenase -
Leptospira interrogans
Length = 460
Score = 120 bits (289), Expect = 8e-26
Identities = 116/447 (25%), Positives = 199/447 (44%), Gaps = 39/447 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LM 77
+YD+ VIG G GG +G K+ V++ P GGTC+N GCIP K L+
Sbjct: 3 EYDIIVIGTG-GGTKLVTPPSKIGYKIAVIEKENP---------GGTCLNRGCIPSKMLI 52
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHI--KSVNWVTRVDLREKKID 135
+ A +L + H +++ ++++ L E + + +S + + D + I
Sbjct: 53 YPAEILSLTKHSEK---FQISFPKKPEVDFKTLIERISKTVDDESASILPAYD-KNPNIT 108
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG-AVEYCISSDDIFS 194
Y++G F + NG +++TAK I IA G RP PDIPG A ++S +
Sbjct: 109 YISGTASFISDKVITV---NG--EQLTAKRIFIASGARPAIPDIPGLAGTPFMTSRETLR 163
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGV 254
P +V+G G+I LE +S G T LVR+ L+ D+ + E E+
Sbjct: 164 RTDLPKSMIVIGGGFIALELGFAYSSFGSEVTFLVRNRMLKNEDKD----IVDEFERIFT 219
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVF---DTVLMATGRYALTKTLNLEAA 311
HN + ++ K+E + E +G+ + + +L+ATG T LNL+
Sbjct: 220 KEHNVLLHTNIHKIEYNK---NLFYVEAISQGKTILLQSEALLVATGIRPNTDLLNLQNT 276
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQ-PM 370
+ N ++ E +T +YA+GD+ GK G L R ++ + P+
Sbjct: 277 NIQTDKNGYIVVNEYLETTSPGVYALGDI-TGKYFYRHSVNFEGEFLFRTLYQEKKRTPI 335
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
+Y V VFT + VG +EE L + G D V +++ + + +
Sbjct: 336 EYPPVPHAVFTHPQIAKVGKTEE-ELIQEGIDYVAAKNSY---SASATGMARLSDSGFVK 391
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGF 457
+ + + +++LG H +G A +I F
Sbjct: 392 ILIDKKSKKVLGAHVIGDEASNLIHLF 418
>UniRef50_Q11NC9 Cluster: Dihydrolipoyl dehydrogenase; n=4;
Alphaproteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Mesorhizobium sp. (strain BNC1)
Length = 462
Score = 120 bits (289), Expect = 8e-26
Identities = 121/449 (26%), Positives = 194/449 (43%), Gaps = 30/449 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
D+DL VIG G GG A A G +V +D + GGTC+NVGCIP K +
Sbjct: 3 DFDLIVIGAGPGGYVAALRAAQAGMRVACID--------ERATAGGTCLNVGCIPSKALL 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ + +G E +A +++ + + + + +++++
Sbjct: 55 SSTEHWAGLKSLADHGIET---EAARVDLSRMMARKDKVVSDLTKSIAFLFNKAGVEFIH 111
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLGH 197
G + + +EI++++I+IA G P P++P + +SS SL
Sbjct: 112 GRASIAAPGRVTVGV-----REISSQHILIATGSAPAVLPNVPFDEKLVLSSTGALSLAK 166
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEMEQKGV 254
P + +VVGAG IGLE + LG TV L R +P G D + A+ ++G+
Sbjct: 167 VPDRLVVVGAGVIGLEIGQIWSRLGAKVTVVEYLDRILP--GMDGETAKNAQRIFARQGI 224
Query: 255 VFH-NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
F N V V+ ET ++K + + + E+ + D VL+A GR T L LEA V
Sbjct: 225 GFMLNAAVEAVVDNGETAEIKIKSRASGKVEKLQ--ADAVLVAIGRKPHTGGLGLEALRV 282
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ + E +T+V I A+GDV+ G P L A + DY
Sbjct: 283 RRDARGFIEVDEQFRTSVPGILAIGDVVPG-PMLAHKAEEDAVACIDALAGKPHCAPDYG 341
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
V V+T E VGL+E+ A A A + I + + K +A
Sbjct: 342 LVPGVVYTTPEIAGVGLTEDDASAAGRAVLIGKASFLANGRARAI---GTTDGFAKVIAC 398
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
E ++LG H +G AGE++Q A++
Sbjct: 399 AET-GKLLGAHILGHGAGELLQELVLALR 426
>UniRef50_A7I8G1 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Candidatus
Methanoregula boonei 6A8|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Methanoregula boonei (strain 6A8)
Length = 462
Score = 120 bits (289), Expect = 8e-26
Identities = 127/450 (28%), Positives = 213/450 (47%), Gaps = 37/450 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGA-KVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+YDL +IG G+ G+A A AV+LGA +V V++ +G WG TCVN GCIP K +
Sbjct: 4 EYDLVIIGTGAAGVAAATAAVHLGASRVAVVE------RGPLWG---TCVNTGCIPSKFL 54
Query: 78 HQAALLGESIHEAVAY-GWEVPS-LDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKID 135
L G + + ++ G + LD ++ A +Q ++ T ++
Sbjct: 55 --LTLAGYTYYRGHSHPGVRMEGRLDLGEVL--AEKNTLQERLREKKRDTLFS--RLGVE 108
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDIF 193
+ G F + HTL A G +K + +K +IA G P P + G +V + S+D +
Sbjct: 109 LIEGEATFLNPHTLQA----GDRK-LASKRFIIATGSSPAIPPVEGIGSVPFMTSADAL- 162
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQ-QMAQAVTSEMEQK 252
S P +V+G +GLE A + LG T+L RS + ++ ++A + + +
Sbjct: 163 SPERIPATLIVIGGRALGLEFAQLYSHLGTRVTLLQRSPRILPEEEPEIADLMAGYLAGE 222
Query: 253 GVVFHNKCVPLSVEKLE-TGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAA 311
G+ + ++++E TG A T ++R D +L+ATGR ++ LN AA
Sbjct: 223 GIGI---LTGVDIKRVERTGDSVAVIAGTRGEQRVISA-DRLLLATGRTPNSRELNCGAA 278
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
GV + ++ QT+ +I+A GDV G+P L A + G + A + +
Sbjct: 279 GVDTRPDGAVVVDTMLQTSAPHIWAAGDV-TGEPMLETAARYGGEIAASNALRELKRSYN 337
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAV 431
+ +FT + VG++E+ A + G + V +F I + R +K V
Sbjct: 338 SALLPHGIFTTPQVAGVGMTEDRA-QKAGLNPVSHSIRTDSMAKFSI-DGDTRG-MVKIV 394
Query: 432 ALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
A + + +RILG+H P+A E+IQ AV
Sbjct: 395 ADKRS-RRILGVHLCAPLATEMIQEGVIAV 423
>UniRef50_A7IDF4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor; n=9;
Alphaproteobacteria|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region precursor -
Xanthobacter sp. (strain Py2)
Length = 448
Score = 120 bits (288), Expect = 1e-25
Identities = 125/446 (28%), Positives = 189/446 (42%), Gaps = 31/446 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDLA+IG G+ + A G V V D+ P GGTC GC PKK+M
Sbjct: 5 YDLAIIGTGTAAIVTAHRVRAAGWSVAVADF---RP------FGGTCALRGCDPKKMMVG 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + G E DA ++W L ++ V +K I +G
Sbjct: 56 GAEAADHAWRMSGRGIEG---DAT-LDWTGLMAFKRSFTDPVPQKREKAFADKGIHAFHG 111
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
F + L + G ++ I A IVIA G IPG ++ I+++ L P
Sbjct: 112 HVRFIGPNAL----EFGGER-IEADRIVIAAGAEAVPLGIPGE-QHLITNEGFLELESLP 165
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVFHN 258
+ ++VG GYI E + G T+L L+ FD + + + ++G+
Sbjct: 166 ERIVLVGGGYIAAEFSHIAARAGAQVTILQHGKRMLKQFDPDLVGWLMDKFSERGINVRT 225
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+ ++EK+ G + R + E D D V+ A GR TL+L+A V +
Sbjct: 226 QAGVTAIEKVSDGY-RVR-ADCPDGELDMDA-DLVVHAAGRAPALATLDLDAGSVK--HH 280
Query: 319 SGKIIAETEQTNVSN--IYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
+G++ +VSN +YA GD P LTPV+ H ++++ + G T +Y V
Sbjct: 281 NGRLALNGFLQSVSNPAVYAAGDAAGLGPPLTPVSSHDAKVVSANLLNGNTVRPEYTGVP 340
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
+ FT VG+SE A AR V V + +F ++ Y +
Sbjct: 341 SVAFTIPPIAAVGMSE--AKAREKGLNVRV--KTERVDGWFTARQQAETVYGFKTLVDAD 396
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
RILG H VGP A EVI FA A++
Sbjct: 397 TDRILGAHLVGPHADEVINIFALAIR 422
>UniRef50_Q9S2Q6 Cluster: Dihydrolipoyl dehydrogenase; n=32;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Streptomyces
coelicolor
Length = 486
Score = 119 bits (287), Expect = 1e-25
Identities = 121/442 (27%), Positives = 200/442 (45%), Gaps = 41/442 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL ++GGGSGG A A LG V +++ K LGGTC++ GCIP K +
Sbjct: 33 FDLVILGGGSGGYAAALRGAQLGLDVALIE---------KNKLGGTCLHNGCIPTKALLH 83
Query: 80 AALLGESIHEAVAYGWEVP--SLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
A + + E+ +G + +D ++ E + K + + + +KI Y+
Sbjct: 84 AGEVADQSRESEQFGVKTSFEGVDMAGVH-KYKDEVIAGLYKGLQGL----VASRKITYI 138
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLG 196
G G ++ NG + + +++++A G P P + ISSD +L
Sbjct: 139 EGEGRLSSPTSVDV---NGQR--VQGRHVLLATGSVPKTLPGLEIDGNRIISSDHALTLD 193
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEMEQKG 253
P +V+G G IG+E A S G TV L VP+ D+ ++ + ++G
Sbjct: 194 RVPKSAIVLGGGVIGVEFASAWKSFGSEVTVIEGLKHLVPVE--DENSSKLLERAFRKRG 251
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ F+ + +K E Q + + +E +V +L+A GR +++ L E GV
Sbjct: 252 IKFN---LGTFFQKAEYTQDGVKVTLADGKEFEAEV---LLVAIGRGPVSQGLGYEENGV 305
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
++ E +TNV I AVGD++ +L V G L+A R+ T P+DYD
Sbjct: 306 A-TDRGFVLVDEYMRTNVPTISAVGDLVPTL-QLAHVGFAEGILVAERLAGLKTVPVDYD 363
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNC-YLKAVA 432
V + E VGL+E A +GADKV V F P R ++ +K V
Sbjct: 364 GVPRVTYCHPEVASVGLTEARAKEVYGADKV-VSIKF--PLGGNGKSRILKTAGEIKLVQ 420
Query: 433 LREAPQRILGLHFVGPVAGEVI 454
+++ ++G+H VG GE +
Sbjct: 421 VKDG--AVVGVHMVGDRMGEQV 440
>UniRef50_Q5FGZ4 Cluster: Dihydrolipoyl dehydrogenase; n=11;
Rickettsiales|Rep: Dihydrolipoyl dehydrogenase -
Ehrlichia ruminantium (strain Gardel)
Length = 474
Score = 119 bits (287), Expect = 1e-25
Identities = 121/451 (26%), Positives = 200/451 (44%), Gaps = 29/451 (6%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LM 77
+YD+ VIGGG GG CA + LG KV +D LGGTC+ VGCIP K L+
Sbjct: 12 NYDVVVIGGGPGGYKCAIRSAQLGLKVACVD--------KNEILGGTCLRVGCIPSKALL 63
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
H E H + +++ N + +I + KID +
Sbjct: 64 H---FSHEYYHIKNHLDEVGITCNSLSFNLDKIMSFKNKNITELGNGINYLFASNKIDRL 120
Query: 138 NGLGEFKDAHTL---IATLKNGSKKEITAKNIVIAVGGR-PHYPDIPGAVEYCISSDDIF 193
G+G+ + ++ I N +++ITAK +VIA G +P I +SS
Sbjct: 121 CGVGKIRSINSNNFDITVTGNNGEEKITAKYVVIATGSEVASFPGIEIDENNVVSSTAAL 180
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEME 250
S P K +VVGAG IGLE + + G TV L + P D +++A+ + ++
Sbjct: 181 SFKEVPKKLVVVGAGAIGLEMSSVWSRFGSEVTVVEFLDKIAP--SMDIDISKALLASLK 238
Query: 251 QKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
++G+ F S++K + L ++ + + + VL++ GR T L ++
Sbjct: 239 KQGINFKLSTKVTSIDK-SSDNLTIHLESVKDGKSEIIEAEKVLISIGRIPYTDGL-IDQ 296
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
+ C S + +TN+ I+A+GDV+ G L A G +A + AG +
Sbjct: 297 NCIECDSRGFIKVNNKYETNIPGIFAIGDVI-GGAMLAHKAEEEGIAVA-ELIAGNIPHV 354
Query: 371 DYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKA 430
DYD + + ++T +G +EE+ + A V + F + I N ++K
Sbjct: 355 DYDIIPSVIYTHPAVASIGKTEESLKNINYAYNVGKSN-FSANSRSKI--TNNGEGFVKV 411
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ +E ILG+H +G A +I A A+
Sbjct: 412 LTSKE-NNAILGVHIIGAYADTIINEAAIAM 441
>UniRef50_A1SYC1 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Proteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Psychromonas ingrahamii (strain 37)
Length = 463
Score = 119 bits (287), Expect = 1e-25
Identities = 117/445 (26%), Positives = 199/445 (44%), Gaps = 33/445 (7%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ +IGGG GG A +A KV +++ K +GG C+N GCIP K +
Sbjct: 7 EYDVIIIGGGPGGYVSAIKAAQNNLKVALVE---------KDKMGGICLNWGCIPTKALL 57
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
++ +H+A +G V D + ++ ++ K++N VD KK N
Sbjct: 58 KSGEFINKLHKANDFGVVV---DKFSFDLKSIVNRSRDISKNLN--KGVDALMKK----N 108
Query: 139 GLGEFKDAHTLIATLKNG-SKKEITAKNIVIAVGGRPHY-PDIPGAVEYCISSDDIFSLG 196
G+ F D +I+ K S + + KNIVIA G + P + + + +
Sbjct: 109 GITVFNDTAKIISNHKVALSNQTLNTKNIVIATGSKSKIIPGLEPDGNVVWNYRNAMTPK 168
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQK-GVV 255
P L++GAG IG+E A F NSLG T++ + + A+ + K G+
Sbjct: 169 KVPENLLIIGAGAIGVEFACFYNSLGSNVTIVENQENILSTEDDDVSALAKKHFIKLGIS 228
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
N V +E + ++ T + VFD V+MA G + LE G+
Sbjct: 229 ILNS---TKVNFIEKSKDSITFELTSENFKETKVFDNVIMAIGVSGSFDNIGLETLGIK- 284
Query: 316 VSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMF-AGATQPMDYD 373
+N G I E QTNV NIYA+GDV G P L A H G + ++ + ++ +
Sbjct: 285 -TNHGFIETNEFMQTNVPNIYAIGDV-AGAPCLAHKASHEGIICIEKILNKNNIKTLNNN 342
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
++ + +++ + +GL+E+ +A + V + I + ++K +
Sbjct: 343 SIPSCIYSYPQIASLGLTEKAVIA--SGETYTVGRFPFNANGKAIASGE-TDGFIKTLFS 399
Query: 434 REAPQRILGLHFVGPVAGEVIQGFA 458
+ +LG+H +G E+IQG+A
Sbjct: 400 ANTGE-LLGVHMIGAEVTEMIQGYA 423
>UniRef50_Q6MDA0 Cluster: Probable soluble pyridine nucleotide
transhydrogenase; n=1; Candidatus Protochlamydia
amoebophila UWE25|Rep: Probable soluble pyridine
nucleotide transhydrogenase - Protochlamydia amoebophila
(strain UWE25)
Length = 465
Score = 119 bits (286), Expect = 2e-25
Identities = 123/445 (27%), Positives = 198/445 (44%), Gaps = 42/445 (9%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+ +IG G G A +A LG V V++ P+ LGG C+ G IP K +A
Sbjct: 7 DIVIIGSGPAGQKAAIQAAKLGKNVIVIE---KEPE-----LGGACLYSGTIPSKTFREA 58
Query: 81 ALLGESIHEAVAYGWE--VPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+ H+ G + +P++ ++N V N +++ +TR ++ I +
Sbjct: 59 VVDLTRFHDRHFAGKDYILPNVTIDELN--VRLHTVINEERNI--ITR-QFKKNSIRVIQ 113
Query: 139 GLGEFKDAHTLIATLKNGSKK-EITAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFSLG 196
G F++ HTLI + K +I A + +IA G P P D+P + + S + +G
Sbjct: 114 GSARFENQHTLIVVDNDFRLKYQIKATSFIIATGSNPRNPPDVPFDQQVILDSTTLLGIG 173
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRS---VPLRGFDQQMAQAVTSEMEQKG 253
P +V+G G IG E A F +LG TV+ R +PL D ++ + + + G
Sbjct: 174 RVPKSMIVLGGGIIGSEYASFFAALGTEVTVIDRKDHMLPL--LDAEIGIHLQTALTDIG 231
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ F K P+ + ++E ++++ + E D +L A GR A + L++E G+
Sbjct: 232 LKFLGKKEPVEISRVE-DHAYVKFKDGSSLEA-----DVLLYALGRLANIEALHVENTGI 285
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQ--PMD 371
+ + QT + +IYAVGDV+ G P L ++ GRL AR T P
Sbjct: 286 IVDAKGYIPVNALFQTVIPHIYAVGDVI-GGPCLASTSMEQGRLAARHACGVQTHHFPTF 344
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNI--RNCYLK 429
Y ++T E G +EE A EV A Y + I + +I N L
Sbjct: 345 Y---PVGIYTIPEISSCGYTEEELKA--WGFHYEVGRAHY----YEIARSHIAGSNTGLF 395
Query: 430 AVALREAPQRILGLHFVGPVAGEVI 454
+ ILG+H +G A EVI
Sbjct: 396 KILFHAETLEILGVHVIGRNATEVI 420
>UniRef50_Q50068 Cluster: Dihydrolipoyl dehydrogenase; n=33;
Actinomycetales|Rep: Dihydrolipoyl dehydrogenase -
Mycobacterium leprae
Length = 467
Score = 119 bits (286), Expect = 2e-25
Identities = 108/386 (27%), Positives = 175/386 (45%), Gaps = 31/386 (8%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
YD+ V+G G GG A A LG V++ P+ WG G C+NVGCIP K L+H
Sbjct: 4 YDVVVLGAGPGGYVAAIRAAQLGLSTAVVE-----PK--YWG--GICLNVGCIPSKVLLH 54
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A L EA +G + I + + + + V+++ +++ KI ++
Sbjct: 55 NAELAHIFTKEAKTFGISGDASFDYGIAYDRSRKVSEGRVAGVHFL----MKKNKITEIH 110
Query: 139 GLGEFKDAHTLIATLKNGSKK---EITAKNIVIAVGGRPHYPDIPGAV--EYCISSDDIF 193
G G F DA+TL L G + ++T N++IA G + +PG + I+ ++
Sbjct: 111 GYGRFTDANTLSVELSEGVPETPLKVTFNNVIIATGSKTRL--VPGTLLSTNVITYEEQI 168
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATV---LVRSVPLRGFDQQMAQAVTSEME 250
P ++VGAG IG+E L + G T+ L R++P D ++++ + + +
Sbjct: 169 LTRELPDSIVIVGAGAIGIEFGYVLKNYGVDVTIVEFLPRAMPNE--DAEVSKEIEKQFK 226
Query: 251 QKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA 310
+ G+ S+ + L A ++ + QE D VL A G L+
Sbjct: 227 KMGIKILTGTKVESISDNGSHVLVAVSKDGQFQELKAD---KVLQAIGFAPNVDGYGLDK 283
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
GV ++ I + QTNVS+IYA+GDV GK +L VA G + A + T +
Sbjct: 284 VGVALTADKAVDIDDYMQTNVSHIYAIGDV-TGKLQLAHVAEAQGVVAAEAIAGAETLAL 342
Query: 371 -DYDNVATTVFTPLEYGCVGLSEETA 395
DY + F GL+E+ A
Sbjct: 343 SDYRMMPRATFCQPNVASFGLTEQQA 368
>UniRef50_A3EPX8 Cluster: Dihydrolipoyl dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Dihydrolipoyl
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 462
Score = 118 bits (285), Expect = 2e-25
Identities = 102/380 (26%), Positives = 169/380 (44%), Gaps = 25/380 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL V+GGG G A A +LG KV +++ K +GGTC++ GCIP K++ +
Sbjct: 5 FDLVVVGGGPAGYVGAIRAAHLGMKVGLVE-------SDK--VGGTCLHEGCIPTKVLLE 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA + + +G S+ ++W L+ + + + + LR+ I + +G
Sbjct: 56 AAGFVSQVARSGEFG---VSVGVPSVDWKTLSAHREKVVSRLFLGIQALLRKNGILHFSG 112
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPH-YPDIPGAVEYCISSDDIFSLGHP 198
G+ + + G K++ A +I++A G RP +P +P E + S D L
Sbjct: 113 EGQLVSPEEVF--VSGGENKKLRASHILVATGSRPRPWPGLPFDRERVLDSTDALRLSPA 170
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL---VRSVPLRGFDQQMAQAVTSEMEQKGVV 255
+ +VG G +G+E A S G T+L R +PL D + + E E++G+
Sbjct: 171 GHRIGIVGGGVVGVEFADIFQSFGGDVTLLEKEERLLPLE--DPDLVDILRKEYERRGMS 228
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTC 315
+S+E +E G + + + E VFD +L+A GR A +G+
Sbjct: 229 IR---TGVSIETIEVGPEGVKITGVDGSGKKELVFDKLLVAIGREARLPAFGKGFSGLPM 285
Query: 316 VSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
K + T +S +YA GDV G L A H + RM P D +V
Sbjct: 286 ERGFLK-VDPYGWTGLSGLYAAGDVTGGL-MLAHAASHQAVIAVDRMAGKNPSPFDPSHV 343
Query: 376 ATTVFTPLEYGCVGLSEETA 395
V++ E VG+S + A
Sbjct: 344 PRVVYSHPEVVSVGISGQEA 363
>UniRef50_Q2JND9 Cluster: Dihydrolipoyl dehydrogenase; n=3;
Cyanobacteria|Rep: Dihydrolipoyl dehydrogenase -
Synechococcus sp. (strain JA-2-3B'a(2-13))
(Cyanobacteria bacteriumYellowstone B-Prime)
Length = 460
Score = 118 bits (284), Expect = 3e-25
Identities = 118/455 (25%), Positives = 200/455 (43%), Gaps = 43/455 (9%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
++D+DL +IG G GG A AV G K ++ +G + +GGTC+N GCIP K
Sbjct: 2 SFDFDLIIIGAGVGGHGAALHAVESGLKTAIV-------EGAE--MGGTCINRGCIPSKA 52
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVD----LREK 132
+ A+ + + G +V SL ++N EA+ NH V R D L +
Sbjct: 53 LLAASGRLRELQHSSGLGIQVGSL---QVN----REAIANHAAQVVEKIRADMTRSLEKL 105
Query: 133 KIDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP---DIPGAVEYCISS 189
+ + G G+ + + GS TA+++++A G RP P ++ G + +S
Sbjct: 106 GVTILRGRGKLVAPQQVEVQEEKGS-HTYTAQDVILATGSRPFVPPGIEVDGRTVF--TS 162
Query: 190 DDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTS 247
D+ L P + ++G+GYIG E A +LG +L+ ++ + FD +A+
Sbjct: 163 DEAVRLEWIPERLAIIGSGYIGQEFADIYTALG-SQVILIEALETLMPAFDPDIARLAQR 221
Query: 248 EMEQKGVVFHNKCVPLSVEKLETGQ-LKARWQNTETQERGEDVFDTVLMATGRYALTKTL 306
+ + + V + ++ GQ + N ET + D L+A GR +++ L
Sbjct: 222 VLIKPRSI--QTFVGVLARQVIPGQPVTIHLSNGETLQ-----VDGCLVAAGRIPVSEGL 274
Query: 307 NLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGA 366
L G+ + T++ +++A+GDV GK L A GR+ + G
Sbjct: 275 GLAELGIDTGKRGFIPVDSRMATDLPHLWAIGDV-TGKMMLAHAAAAQGRVAVENI-CGR 332
Query: 367 TQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNC 426
T MDY ++ VFT E G VGL+E A+ V ++ I
Sbjct: 333 TAYMDYLSIPAAVFTHPEMGFVGLTEPQ--AKEEGYSVGTVRTYFGGNSKAIASGETEG- 389
Query: 427 YLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ + ++ +LG H GP A ++I A A+
Sbjct: 390 -MVKLVFDKSTGLLLGSHIFGPHAADLIHEAAQAI 423
>UniRef50_Q2B857 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Bacillus sp. NRRL B-14911|Rep: Dihydrolipoamide
dehydrogenase - Bacillus sp. NRRL B-14911
Length = 476
Score = 118 bits (284), Expect = 3e-25
Identities = 122/442 (27%), Positives = 199/442 (45%), Gaps = 30/442 (6%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
Y+ D+ +IGGG GG A A LG KVT+++ K LGG C++ GCIP KL
Sbjct: 8 YEKDVVIIGGGPGGYQAAIRAAQLGRKVTLIE---------KADLGGVCLHKGCIPSKLF 58
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
+AA I A YG E+ S A ++ + E + + V + + +I+ V
Sbjct: 59 AEAADRIRKIKAAGEYGIEL-SFSAFQLE-KLMNEKDRKTAQLKKGVEEL-CKSNEIELV 115
Query: 138 NGLGEFKDAHTLIATLKNGSKKEI-TAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFSL 195
G F A + ++NG ++ K+ +IA G P +P D E + +FSL
Sbjct: 116 KGNAFFLSADRM--GIENGEAYQVFRFKHCLIATGSTPIWPHDNSPRSEKLLDCWSVFSL 173
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV-RSVPLRGFDQQMAQAVTSEMEQKGV 254
P + ++ G+GYI LE A + G ++++ + GFD + + + +++ +
Sbjct: 174 KKLPDELIIYGSGYIALEMAMSFQAFGARTSIMLDQEKDDFGFDAAVNREIGRILKKNRI 233
Query: 255 VFHNKCVPLSVEKLETG-QLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ LSVE+ +G ++ Q +G L A G T L L+ AGV
Sbjct: 234 KVYRGAKLLSVEESGSGVEINYELGGENKQLKG----SCFLTAAGFRPNTANLGLDRAGV 289
Query: 314 TCVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
+ +G I I + +T+VS+I+A GDV +G P L AI G+ A + AG D
Sbjct: 290 E-IDTAGFIKIDQQGKTSVSHIFAAGDVADG-PPLASKAIRQGKAAAETI-AGLKTEADL 346
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
+ T GL+E+ AL K++ F + + + R K +
Sbjct: 347 RFAPVVIHTQPPIAYAGLTEQEAL--EAGYKIDT-GIFPFSSLGYASVKGSREGMAKVIF 403
Query: 433 LREAPQRILGLHFVGPVAGEVI 454
+E +LG+H +G A E+I
Sbjct: 404 EKET-GFLLGVHMIGDGAQELI 424
>UniRef50_A3ESJ6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide dehydrogenase component; n=1;
Leptospirillum sp. Group II UBA|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dihydrolipoamide dehydrogenase component -
Leptospirillum sp. Group II UBA
Length = 461
Score = 118 bits (283), Expect = 4e-25
Identities = 125/449 (27%), Positives = 187/449 (41%), Gaps = 35/449 (7%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMHQ 79
DL VIG GS G A+ A +LG V +++ K GG C+ GC+P K L+
Sbjct: 6 DLLVIGAGSAGRYAARSAASLGKSVLLVE---------KGPFGGLCILKGCMPSKALLRP 56
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A + H G V ++K + PA+ I+ + D R K I+ G
Sbjct: 57 AHVFHLMKHRLKDLGLSVDG--SVKADIPAIVRMKNAMIREM----AEDAR-KTIEATPG 109
Query: 140 L----GEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE-YCISSDDIFS 194
+ G F L + + VIA G R H P IPG E + ++SDD+
Sbjct: 110 ITLLTGNFSFTGPQAGLLGD---TPVHFDKAVIATGSRVHVPAIPGLEEEWILTSDDVLE 166
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLR-GFDQQMAQAVTSEMEQKG 253
+ P TLV+G G +GLE +L+ LG T+ + D Q+A+ + +G
Sbjct: 167 MEEIPSSTLVLGGGPVGLELGQYLSCLGSDVTLADTNQNWHPQTDPQLAREYLGTLASRG 226
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAG 312
+ H + + EK E G + + + + V FD VL+ATGR T LNL AA
Sbjct: 227 LNIH---LGIRAEKFERGAGEKPFFSFHADGKNHKVPFDRVLLATGRRPDTSGLNLPAAQ 283
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
V + + +T+ +I+A GDV P L H G + R +
Sbjct: 284 VQTTRHGHIQVDAFLRTSNHSIFAAGDVTGILPVLNLATFH-GEMAGRNAVLPVPVTVRE 342
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
V +FT EY GL+E A AR V+ + I R LK +
Sbjct: 343 PVVPVAIFTDPEYARAGLTESMAQARR--IPVKTGRISFSDLGKAIVYRETEG-GLK-IV 398
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ + ILG+ GP A +++ A A+
Sbjct: 399 VHAKSREILGVELFGPGASDLVHTVATAM 427
>UniRef50_Q6LLT9 Cluster: Soluble pyridine nucleotide
transhydrogenase (EC 1.6.1.1) (STH) (NAD(P)(+)
transhydrogenase [B-specific]); n=88; cellular
organisms|Rep: Soluble pyridine nucleotide
transhydrogenase (EC 1.6.1.1) (STH) (NAD(P)(+)
transhydrogenase [B-specific]) - Photobacterium
profundum (Photobacterium sp. (strain SS9))
Length = 469
Score = 118 bits (283), Expect = 4e-25
Identities = 119/440 (27%), Positives = 187/440 (42%), Gaps = 30/440 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D +IG G GG A G V V++ +GG C + G IP K +
Sbjct: 10 FDAIIIGSGPGGEGAAMGLTKAGLNVAVIEREN--------SVGGGCTHWGTIPSKALRH 61
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A ++ Y SL + + + Q+ + + + K + G
Sbjct: 62 AVSRIIEYNQNPLYCKNNSSLHS---TFSQILGHAQDVVNKQTRMRQGFYDRNKCSLIFG 118
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPD-IPGAVEYCISSDDIFSLGHP 198
F DAHT+ + S +A VIA G RP++P+ + SD I L H
Sbjct: 119 EASFIDAHTVRVKNADNSTDLYSADKFVIATGSRPYHPEGVDFDHSRVYDSDSILQLEHD 178
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P ++ GAG IG E A LG ++ R L D +++ +++ + G +
Sbjct: 179 PRHIIIYGAGVIGSEYASIFRGLGVKVDLINTRHRLLEFLDNEISDSLSYHLWNSGAMIR 238
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
N + EK+E G + + E+ ++ D +L A GR T LNL G+T S
Sbjct: 239 NG---ETFEKIE-GTDDSIILHLESGKKMRA--DCLLYANGRTGNTDKLNLNKVGLTPDS 292
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
+ + T+V ++YAVGDV+ G P L A GR +A+ + G Q D++ T
Sbjct: 293 RGQLAVNQNYCTDVDHVYAVGDVI-GYPSLASAAYDQGRFVAQAITTGEAQGSLIDHIPT 351
Query: 378 TVFTPLEYGCVGLSEETALARHGADKV--EVYHAFYKP-TEFFIPQRNIRNCYLKAVALR 434
++T E VG +E+ ADKV EV + +K I + + LK + R
Sbjct: 352 GIYTIPEISSVGKTEQQLT----ADKVPYEVGRSQFKHLARAQIAGTEVGS--LKILFHR 405
Query: 435 EAPQRILGLHFVGPVAGEVI 454
E + ILG+H G A E+I
Sbjct: 406 ET-KEILGIHCFGERAAEII 424
>UniRef50_Q74AD0 Cluster: Dihydrolipoyl dehydrogenase; n=17;
Proteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Geobacter sulfurreducens
Length = 472
Score = 117 bits (281), Expect = 8e-25
Identities = 118/445 (26%), Positives = 193/445 (43%), Gaps = 32/445 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+DL VIG G GG A A LG V V + + LGG C+N GCIP K +
Sbjct: 6 FDLIVIGAGPGGYVAAIRAAQLGMTVAVAEQ--------RETLGGVCLNEGCIPSKALLD 57
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
++ + A G + +D +++ + + +K + ++ +I ++ G
Sbjct: 58 SSEFFAQARDGFA-GHGI-LIDPPRLDLARMMARKDDVVKKLTDGIAYLFKKNRITWLKG 115
Query: 140 LGEFKDAHTLIATLK---NGSKKE--ITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIF 193
+ + ++ NG+ + A +++A G P + E +S+ +
Sbjct: 116 TARLAGRNGDLLRVEVGGNGTAPAHLLEAGKVLLATGSEAVPVPGLAFDGETVVSAREAL 175
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQK 252
+ P LVVGAGYIGLE LG TV+ V + PL D Q+A A+ ++++
Sbjct: 176 AFDRVPEHLLVVGAGYIGLELGSVWRRLGSQVTVVEVLAKPLPATDGQVADALVRSLKKQ 235
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVF--DTVLMATGRYALTKTLNLEA 310
G+ F + +EK E + E+ G D D VL+A GR + L LE
Sbjct: 236 GISFRMETRVTGIEKREGTAV----VTVESSAGGRDAIACDRVLVAAGRRPVMAGLGLEP 291
Query: 311 AGVTCVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
+ G+I + + T+ IYA+GD++ G P L A+ G + A R+ G
Sbjct: 292 FNL--AMEGGRIRVDDNYLTSAPGIYAIGDLIHG-PMLAHKAMAEGEVFAERL-TGEASV 347
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
+DY+ + V+T E VGL+EE L G F ++K
Sbjct: 348 VDYEYIPGIVYTWPEAAGVGLTEE-QLKEQGIPYAAGRFNFMANGRARCMGET--EGFVK 404
Query: 430 AVALREAPQRILGLHFVGPVAGEVI 454
+A + R+LG+H VGP A ++I
Sbjct: 405 ILA-KPDTGRVLGIHVVGPRASDLI 428
>UniRef50_Q01WF2 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=1; Solibacter
usitatus Ellin6076|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase - Solibacter
usitatus (strain Ellin6076)
Length = 468
Score = 117 bits (281), Expect = 8e-25
Identities = 115/445 (25%), Positives = 194/445 (43%), Gaps = 36/445 (8%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T YDL IG G G + + A G + V++ P GGT G P K
Sbjct: 2 TDTYDLIAIGSGPAGESATELAAFFGHRCAVVERARP---------GGTVTTTGGAPTKT 52
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
+ +AAL + + YG ++ + + + + + + VT ++ + +DY
Sbjct: 53 LREAALYFSGLVDGDVYGIKISTPPEVATE--VIRKRTWHVCDLLQKVTGENIAKNNVDY 110
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDDIFSL 195
+ G + ++ T +GS++ + A +++A G RP P +IP + +D I
Sbjct: 111 IQGAARLEGDGKVMVTGDDGSRRRLRANVLLLATGSRPRRPPNIPFDLAGVCDTDTILQR 170
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKG- 253
G P L+VG G +G+E A ++LG T+ R L D ++ + + G
Sbjct: 171 GRVPKDILIVGGGPVGVEFATIAHALGAKVTLADRGNRLMSMMDGEITECMEELFRTWGI 230
Query: 254 -VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVF-DTVLMATGRYALTKTLNLEAA 311
V+F + C + V K + ++ T GE + DTVL A GR T L L+AA
Sbjct: 231 RVLFGSTCNSV-VAKDDALEI--------TMSTGERLSPDTVLFAAGRVPNTGDLGLDAA 281
Query: 312 GVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
GV + ++ + +T+ +YA GDVL P L +A+ GR+ F + +
Sbjct: 282 GVAMDARGRIVVDQQFRTSAEGVYAAGDVL--GPTLASIAMEQGRVAICHAFGIPFEGIV 339
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNI--RNCYLK 429
+ V+ E G +EE G D EV A T P+ I R LK
Sbjct: 340 DPAPVSAVYGMPEVSGAGRTEEEC-REMGVD-YEVGRADLART----PRGAIAGRGGRLK 393
Query: 430 AVALREAPQRILGLHFVGPVAGEVI 454
+ +E +R++G+H +G +A E++
Sbjct: 394 LIFQKE-DRRLIGVHCIGDIASEIV 417
>UniRef50_Q8K9T7 Cluster: Dihydrolipoyl dehydrogenase; n=33;
Gammaproteobacteria|Rep: Dihydrolipoyl dehydrogenase -
Buchnera aphidicola subsp. Schizaphis graminum
Length = 476
Score = 117 bits (281), Expect = 8e-25
Identities = 106/382 (27%), Positives = 179/382 (46%), Gaps = 28/382 (7%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMHQ 79
++ +IG G G + A +LG + ++++ + LGG C+NVGCIP K L+H
Sbjct: 8 EVVIIGSGPAGYSAAFRCADLGLETVLIEH--------QERLGGVCLNVGCIPSKSLLHI 59
Query: 80 AALLGES--IHEAVAYGWEVPSLDAIKIN-WPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
A ++ ++ + E+ + + P +D KIN W + IK + ++K+
Sbjct: 60 AKIIKDASELSESGVF-FNKPIIDIKKINNWK------EKIIKKLTTGLSNMGEKRKVRI 112
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSL 195
V G F H+++ K I K+ +IA G +P P +P +S D SL
Sbjct: 113 VQGKALFNTDHSVLVKNKKNDFT-IFFKHAIIATGSKPIKIPSLPNEDNRIWNSTDALSL 171
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGV 254
P + L++G G IGLE A ++LG ++ R + L D+ + ++++
Sbjct: 172 KSIPNRFLIIGGGIIGLEMATIYSALGSKVDIVDRFNAFLPSVDKDITDIYIKSIKKRFK 231
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVT 314
+ N V SVEK + L + E + +D +L+A GR L LE G+
Sbjct: 232 LLLNTHVK-SVEKSKDNDLIVKIAE-ENSDENVCCYDNILVAIGRSPNVDFLGLEKIGLK 289
Query: 315 CVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
++ SG I I + +TN+S+IYA+GDV G P L A+ +A + +G +
Sbjct: 290 -LNESGFIEINQQLKTNISHIYAIGDV-TGFPMLAHKAVQQAH-IAAEVISGKKHYFEPK 346
Query: 374 NVATTVFTPLEYGCVGLSEETA 395
+ + +T E VGLSE+ A
Sbjct: 347 VIPSVAYTDPEIAWVGLSEKEA 368
>UniRef50_A5IAB6 Cluster: Pyridine nucleotide-disulfide
oxidoreductase; n=4; Legionella pneumophila|Rep:
Pyridine nucleotide-disulfide oxidoreductase -
Legionella pneumophila (strain Corby)
Length = 464
Score = 116 bits (279), Expect = 1e-24
Identities = 123/446 (27%), Positives = 194/446 (43%), Gaps = 35/446 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D ++GGG GG A + G K+ +++ + Q +GGTC+NV CIP K + Q
Sbjct: 5 FDTIILGGGKGGKTLAMDLAKSGQKIAMVE----NNQ-----IGGTCINVACIPTKTLVQ 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKIN-WPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+A + +A YG +L I A +AV N ++ N +D +D +
Sbjct: 56 SAKVAHYCRKAKDYGLNT-TLHPIDFKAIRARKDAVVNGMREANLKQFLD---SGMDLML 111
Query: 139 GLGEFKDAHTLIATLK----NGSKKEITAKNIVIAVGGRPHYPDIPG--AVEYCISSDDI 192
G G F + TL N ITA I+I G P+ P I G V Y ++D +
Sbjct: 112 GHGHFIGPKMIEVTLSSPRDNQKTLHITADKIIINTGALPYTPPIAGLDKVNY-FTNDSL 170
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRG-FDQQMAQAVTSEMEQ 251
+ P L++G GYIGLE A G TV+ S G D+ +A+ V +
Sbjct: 171 MNTDSVPQHLLIIGGGYIGLEFAQMFRRFGAEVTVIEASSEFLGREDKDIAEQVFQTLSN 230
Query: 252 KGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDT-VLMATGRYALTKTLNLEA 310
+G+ F V + + Q + + Q + E + T VL+A GR A T L+L+
Sbjct: 231 EGIQF---AVDTKINAIRQEQTEVIIE-ANRQGQSEIIRGTAVLVAVGRIANTAGLHLDK 286
Query: 311 AGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPM 370
GV + E +T + I+A+GDV +G + T +++ RL+ + + +
Sbjct: 287 TGVELDERGFIKVNEFLETTAAGIWALGDV-KGGAQFTHLSLDDYRLVKHNL-QNPQKKL 344
Query: 371 DYDN--VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYL 428
N + TVF E +GL+E A ++ K+ A P + L
Sbjct: 345 SSQNRLIPYTVFLDPELARIGLTEAQARSQGRPIKIAKIPAAAIPR---AKTQGETTGVL 401
Query: 429 KAVALREAPQRILGLHFVGPVAGEVI 454
KAV E ILG+ AGE++
Sbjct: 402 KAVIDAET-DLILGVSIFCAEAGEIL 426
>UniRef50_A7BE73 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 465
Score = 116 bits (278), Expect = 2e-24
Identities = 118/452 (26%), Positives = 194/452 (42%), Gaps = 38/452 (8%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP-KKLMHQ 79
DL V+GGG G + A E G KV +++ + +GGTC+NV CIP K L++
Sbjct: 10 DLLVVGGGKAGKSLAMERAKAGWKVAMVE---------RQFVGGTCINVACIPTKSLVNS 60
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A L ++ + A+G V + +++ L + + ++ +D++ G
Sbjct: 61 ARRLSDARSDE-AFG--VVGTEGARVDLAKLRAHKEGIVGAMVGAHEKMFAAPGLDFIRG 117
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLGHP 198
F T+ L++G ++ I + ++I +G RP P IPG E ++++I L
Sbjct: 118 EARFTGERTVTIALEDGGERTIRGERVLINLGSRPARPAIPGLWESGAWTNEEILRLEEL 177
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P ++GAGYIG+E A + + G T++ L D+ A+ V + +E GV
Sbjct: 178 PSSLAIIGAGYIGVEFASMMATFGVDVTLISSGDHVLPREDEDAARVVEAGLEAAGV--- 234
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLEAAGVTCV 316
+ VP + E+ + T T G V + VL+A GR T + L+ AGV
Sbjct: 235 -RIVP---GRAESASREGN-TTTLTLSDGSTVSAEAVLVAVGRVPNTDGIGLDEAGVELT 289
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAG----ATQPMDY 372
+ E +T+ ++A GD G P T + R++ ++ AT
Sbjct: 290 DRGFVAVDEHLRTSAEGVWAAGD-CAGTPMFTHASWSDFRIIRAQLTGASLDEATTTTKG 348
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNC---YLK 429
+ VF E +GLSE AR V + PT + +R + K
Sbjct: 349 RTIPYAVFATPELARIGLSE--GEAREAGLDVRIAKV---PTAAIPRAKTMRYAGEGFWK 403
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
A+ Q ILG +GP EVI A+
Sbjct: 404 AIVDANTHQ-ILGATLIGPNVSEVITAVHVAM 434
>UniRef50_A6CF61 Cluster: Soluble pyridine nucleotide
transhydrogenase; n=1; Planctomyces maris DSM 8797|Rep:
Soluble pyridine nucleotide transhydrogenase -
Planctomyces maris DSM 8797
Length = 496
Score = 116 bits (278), Expect = 2e-24
Identities = 123/440 (27%), Positives = 189/440 (42%), Gaps = 30/440 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ +IG G G A A LG +V +++ G+GG C++ G IP K M +
Sbjct: 3 YDIVIIGSGPAGQKAAIAASKLGKRVAIIER-------NFRGMGGVCLHKGTIPSKTMRE 55
Query: 80 AAL-LGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A L L H V W +I L + + + + L ++
Sbjct: 56 AILYLTGYRHRDVYSKWYRRKR---RITMQDLRLKLADVAEHELEIIHDQLERNGVEVYI 112
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPD-IPGAVEYCISSDDIFSLGH 197
G +F H + + G +K++ I++A G +P P IP E SD+I L
Sbjct: 113 GEAKFVSPHEVEVDCETG-RKQLYGDYILVATGTKPSRPPHIPFDGETIFDSDEIIDLKE 171
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKGVVF 256
P +VVG G IG+E A +LG TVL L F D+++ A+ G++F
Sbjct: 172 IPRSMIVVGGGVIGIEYAIMFATLGVEVTVLDGRERLLEFCDREIIDALIHHARSLGMIF 231
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
+ +E+ + TE+ +R V D+VL GR LN +AAG+
Sbjct: 232 RMGEEVVGIERFSDSMAAVQ---TESGKR--LVADSVLYTVGRVGDADELNFQAAGLEPD 286
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD-YDNV 375
E QT V +IY GD++ G P L V++ GR + F +P + +D +
Sbjct: 287 ERGRLWCNEEHQTWVPHIYGAGDIV-GFPALASVSMEQGRRVICNAF---NEPFEAFDLM 342
Query: 376 ATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQ-RNIRNCYLKAVALR 434
+FT E VG +E+ H EV A Y+ E Q R+ LK + R
Sbjct: 343 PYGLFTIPEISMVGKTEQQLTDAH--IPYEVGAARYR--EIARGQISGDRDGMLKILFHR 398
Query: 435 EAPQRILGLHFVGPVAGEVI 454
E +ILG+H +G A E++
Sbjct: 399 ET-LKILGIHAIGEAATEIV 417
>UniRef50_A3TPL4 Cluster: Pyridine nucleotide-disulphide
oxidoreductase; n=1; Janibacter sp. HTCC2649|Rep:
Pyridine nucleotide-disulphide oxidoreductase -
Janibacter sp. HTCC2649
Length = 453
Score = 116 bits (278), Expect = 2e-24
Identities = 107/379 (28%), Positives = 169/379 (44%), Gaps = 30/379 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D +IG G GG A + G +V +++ Q + GGTC+N+GC+P K
Sbjct: 7 FDAIIIGWGKGGKTLAAFLASRGDRVLMVE------QSDRM-FGGTCINIGCVPTK---- 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AL+ + H ++ +V L+A++ A+ + ++ N+ + VD E + G
Sbjct: 56 -ALVESANHPSLVADADVRYLNAVERK-----NALTSLLRGKNF-SMVDSHESAT-VLTG 107
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAV-EYCISSDDIFSLGHP 198
F H + + N + T+ I+I G P P IPG ++S ++
Sbjct: 108 RARFVGPHEIEVSASN-ERVRATSDRIIINTGSVPVVPPIPGLDGPRVVTSTELIDETDL 166
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGF-DQQMAQAVTSEMEQKGVVFH 257
P + +V+GAG IGLE AG + G TV+ + L D +A AV +E G+ F
Sbjct: 167 PRRLVVIGAGAIGLELAGAYRTFGAEVTVVDSADRLLPREDDDVADAVRQVLEADGISFI 226
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
V+ G + T E D VL+A GR T L LEAAG+
Sbjct: 227 FGATVDHVDDTAAGSV-VHLDGDRTIEA-----DRVLVAVGRRPATDDLGLEAAGIETTD 280
Query: 318 NSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFA-GATQPMDYDNVA 376
++ +T+V ++AVGDV G P+ T V++ R++ ++ GA + D V
Sbjct: 281 RGAVLVDAQLRTSVEGVWAVGDV-NGGPQFTYVSLDDNRIVKDQLVGQGARRTTDRVAVP 339
Query: 377 TTVFTPLEYGCVGLSEETA 395
T F VGLSE A
Sbjct: 340 ATTFITPPLARVGLSESEA 358
>UniRef50_P52992 Cluster: Dihydrolipoyl dehydrogenase; n=34;
root|Rep: Dihydrolipoyl dehydrogenase - Ralstonia
eutropha (strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 474
Score = 116 bits (278), Expect = 2e-24
Identities = 108/383 (28%), Positives = 183/383 (47%), Gaps = 25/383 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLD-YVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+D+ VIG G GG A A LG V + P+G LGGTC+NVGCIP K +
Sbjct: 5 FDVLVIGAGPGGYIAAIRAGQLGLNVACCEGNPYDDPKGEA-RLGGTCLNVGCIPSKALL 63
Query: 79 QAALLGESI-HEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
++ E++ H +G V +K++ + + + + + R+ K+ +
Sbjct: 64 ASSEEFENVQHHLGDHGITVGD---VKVDVAKMLKRKDDIVGKMTKGIEFLFRKNKVTLL 120
Query: 138 NGLGEF--KDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFS 194
G G+F K A + + + +TAK ++IA G + H P I V+ + SD+ +
Sbjct: 121 KGYGKFVGKSAEGFQVDV---AGEVVTAKQVIIATGSKARHLPGI--KVDNDLVSDNEGA 175
Query: 195 LGHP--PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEME 250
L P P K V+GAG IGLE LG TVL ++P L D+ +A+ ++
Sbjct: 176 LKFPAVPKKLGVIGAGVIGLELGSVWRRLGSDVTVL-EALPAFLGAADEGVAKEAQKQLT 234
Query: 251 QKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDV-FDTVLMATGRYALTKTLNLE 309
++G+ F + ++V ++ TG+ + T+ + + + D ++++ GR T L L+
Sbjct: 235 KQGLKF---SLGVNVNEVTTGKNGVTVKYTDKDGKAQTLEVDRLIVSVGRVPNTDNLGLD 291
Query: 310 AAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
A G+ + + T V ++A+GDV+ G P L A G +A R+ AG
Sbjct: 292 AVGLAADQRGFIEVDDHCATKVPGLWAIGDVVRG-PMLAHKAEDEGVAVAERI-AGQKPH 349
Query: 370 MDYDNVATTVFTPLEYGCVGLSE 392
+DY+ V ++T E VG +E
Sbjct: 350 IDYNCVPWVIYTFPEIAWVGKTE 372
>UniRef50_Q98C99 Cluster: Mercuric reductase; n=4;
Proteobacteria|Rep: Mercuric reductase - Rhizobium loti
(Mesorhizobium loti)
Length = 509
Score = 115 bits (277), Expect = 2e-24
Identities = 125/448 (27%), Positives = 196/448 (43%), Gaps = 32/448 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
Y+L VIG G GL A++A +LGAKV +++ +G +GG CVNVG +P K + +
Sbjct: 38 YNLVVIGAGPAGLTAARDAASLGAKVALIE------RGL---IGGACVNVGGVPSKSIIR 88
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
A L + +A +G + P+ + A+ Q + + + + ID G
Sbjct: 89 TARLYADMRDAENFGGDTPARLPVDFE-RAMMRMRQIRQRLSRADSAAAITAEGIDLYFG 147
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSLGHP 198
F T+ + K + K ++A G P P IPG E + ++ +F+L
Sbjct: 148 EARFGGPDTV-----EVAGKTLHFKKALVATGAHPSGPAIPGLAEAGYLDNESMFNLTRR 202
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKGVVF 256
P + LV+G G +G E A LG +L +S P L G ++ AQ ++ + ++GV
Sbjct: 203 PERLLVIGGGPLGCETAQAFCLLG-AKVILAQSDPMFLPGEERDAAQILSDTLAREGVEV 261
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
++V K +L ++ +T D ++ GR + L LE AGV
Sbjct: 262 RLNTEVVAVRKEGGRKLADLLRDGDTTTIS---VDEIITGVGRSPNVRGLGLEEAGVVYD 318
Query: 317 SNSGKIIAETEQTNVSNIYAVGDV-LEGKPELTPVAIHAGRLLARR-MFAGATQPMDYDN 374
+N K+ TN +IYA GDV LE K T A A R++ R +F G + D
Sbjct: 319 ANGIKVDDHLRTTN-PHIYAAGDVCLEYK--FTHTAEAAARIVVRNALFRGRERLSDL-V 374
Query: 375 VATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALR 434
V +T E VGL AR V+ Y + ++K + +R
Sbjct: 375 VPWCTYTDPEIAHVGL--YPIEARQNGIPVKTYTVLMHDVARAVMDGE-EEGFVK-IHVR 430
Query: 435 EAPQRILGLHFVGPVAGEVIQGFAAAVK 462
E RILG V AGE+I A++
Sbjct: 431 EGSDRILGATVVASHAGEMINAVTLAIR 458
>UniRef50_Q03XL9 Cluster: Glutathione reductase; n=1; Leuconostoc
mesenteroides subsp. mesenteroides ATCC 8293|Rep:
Glutathione reductase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 446
Score = 115 bits (276), Expect = 3e-24
Identities = 117/445 (26%), Positives = 187/445 (42%), Gaps = 34/445 (7%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ IG G A+ G KV +++ + + GTC N GC K L+
Sbjct: 2 NYDVIFIGSGHAAWHGAQTLARSGKKVALVE---------ENKVAGTCTNFGCNAKILLD 52
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A E +H Y + D I WP L I ++ L ID +N
Sbjct: 53 GPA---EMMHHLNHYHG-IGINDTPNIIWPELMAYKHQVIDPLSGGLAHMLSVDGIDIIN 108
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHP 198
G +F + ++ + A+ VIA G RP I G+ E+ S D L
Sbjct: 109 GHAKFLNNEKIVVV-----DQVYQAEKFVIATGQRPAKLPISGS-EFMKDSTDFLDLPDM 162
Query: 199 PGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P L VGAGYI +E A ++ G T++ + L GFD+ +Q V +M +KG+ F
Sbjct: 163 PKSILFVGAGYIAMEFASIAHAAGSDVTLIEYGNHVLNGFDEVYSQKVIEDMTEKGIHFT 222
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
SV L GQ + ET D V+ TGR + L L+ V
Sbjct: 223 FNQAVSSVSLLANGQYQVDTAQGETY-----YVDYVMDTTGRVPNIEELALDDINV-LYD 276
Query: 318 NSGKIIAETEQTNVSNIYAVGDVL-EGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVA 376
G ++ + QT++ NIYA GDV+ + P LTP A +A + G +P++Y V
Sbjct: 277 KQGILVNDHLQTSIDNIYASGDVISKAIPRLTPTATFESNYIA-SVLLGNQEPINYPVVP 335
Query: 377 TTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREA 436
T FT +G++ + A + ++V+ Y F ++ + +K + +
Sbjct: 336 TVAFTLPRVAQIGVTIDEAAK---DENLQVHEIPYGRVMRFQTLNDV-HAAIKIIVNKN- 390
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAV 461
++++G +G A EV+ +
Sbjct: 391 -KQLVGAALIGDFAPEVVNALVPVI 414
>UniRef50_Q7MW44 Cluster: Dihydrolipoyl dehydrogenase; n=10;
Bacteroidales|Rep: Dihydrolipoyl dehydrogenase -
Porphyromonas gingivalis (Bacteroides gingivalis)
Length = 449
Score = 114 bits (275), Expect = 4e-24
Identities = 118/452 (26%), Positives = 193/452 (42%), Gaps = 43/452 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YDLA+IGGG G A+ A G K +++ K LGG C+N GCIP K +
Sbjct: 3 YDLAIIGGGPAGYTAAERAAKGGLKTLLIE---------KNALGGVCLNEGCIPTKTLLY 53
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
+A + I A Y S A ++ + I+ + R L E ++ V
Sbjct: 54 SAKVLHQIATASKY---AVSGTADGLDLGKVIARKGKIIRKLTAGIRSRLTEAGVEMVTA 110
Query: 140 LGEFK--DAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISSDDIFSL 195
DA +I + + A N+++ G P IPG EY + + + +
Sbjct: 111 EATVTGCDADGIIGI--TAGEAQYKAANLLLCTGSETFIPPIPGVEQTEYWTNREALQN- 167
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEMEQKG 253
P +++G G IG+E A F N +G V V +P L G D + A + + E++G
Sbjct: 168 KEIPTSLVIIGGGVIGMEFASFFNGIGTQVHV-VEMLPEILNGIDPEHAAMLRAHYEKEG 226
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ F+ + V + G + ++ + GE +LM+ GR + + E+ G+
Sbjct: 227 IKFY---LGHKVTSVRNGAVTVEYEGESKEIEGE----RILMSVGRRPVLQ--GFESLGL 277
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
++ G E QT++ N+YA GD+ G L A+ + ++ + M Y
Sbjct: 278 V-LAGKGVKTNERMQTSLPNVYAAGDI-TGFSLLAHTAVREAEVAVDQILGKTDETMSYR 335
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEF---FIPQRNIRNCYLKA 430
V V+T E VG +EE +L + G Y P F F+ + N K
Sbjct: 336 AVPGVVYTNPEVAGVGETEE-SLRKAG----RAYTVRRLPMAFSGRFVAENEQGNGECK- 389
Query: 431 VALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
L + R++G H +G AGE+I A A++
Sbjct: 390 -LLLDEENRLIGAHLIGNPAGELIVTAAMAIE 420
>UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8;
Mycoplasma|Rep: DIHYDROLIPOAMIDE DEHYDROGENASE -
Mycoplasma pulmonis
Length = 627
Score = 114 bits (274), Expect = 5e-24
Identities = 121/457 (26%), Positives = 198/457 (43%), Gaps = 44/457 (9%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ VIG G GG A+EA G K +++ K GG C+NVGCIP K +
Sbjct: 160 EYDVIVIGAGPGGYLAAEEAGKYGLKTLIIE---------KQYWGGVCLNVGCIPTKALL 210
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKIN----WPALTEAVQNHIKSVNWVTRVDLREKKI 134
A ++ + + V A+KI+ W + + ++ + + + ++ K
Sbjct: 211 HATEELYNLEHSHEHNGIVADFKALKIDRQKTWINIQKNKKSVVDKIVGGVKFLMKAAKA 270
Query: 135 DYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG-----AVEYCISS 189
+ G +F +H L NG K KNI+IA G ++PG E +SS
Sbjct: 271 TSIEGEAKFVGSHELEV---NG--KVYRGKNIIIATGSLDRKLNLPGFEQAYKDEVVLSS 325
Query: 190 DDIFSL-GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRG---FDQQMAQAV 245
D + +L H P ++GAG IG+E A G T++ + + +++ +
Sbjct: 326 DKLINLDSHLPETLGIIGAGVIGVEFAEVFAMAGTKVTIIQNTDAILANAPLAKEIKTEL 385
Query: 246 TSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKT 305
T+ +++ GV F S K+E QL E + FD +L A GR +
Sbjct: 386 TNHLKKYGVEFKFNA---STTKIEKNQLFFEVGGKEESMK----FDKILAAVGR--IPTP 436
Query: 306 LNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAI-HAGRLLARRMFA 364
LN G+ + I+ + TNV N+YA+GDV GK L VA HA R++
Sbjct: 437 LNAGEVGIEIGQRNEIIVDDKLMTNVENVYAIGDV-TGKNMLAHVAYRHAIRVV--ESIV 493
Query: 365 GATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIR 424
G + + ++T E VGL+E+ A G D V ++F +
Sbjct: 494 GEEEVYPKQEIPGCIYTKPEIAFVGLTEQQA-KEAGYDVVTSKYSFSTLGKALASSEG-- 550
Query: 425 NCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
N +++ V ++ RILG H +G + + I A+
Sbjct: 551 NGFVQLVVDKKY-GRILGCHIIGKNSTDYIAEIVLAM 586
>UniRef50_A7EZF7 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 384
Score = 113 bits (273), Expect = 7e-24
Identities = 66/168 (39%), Positives = 93/168 (55%), Gaps = 13/168 (7%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNL-GAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK 75
T + D VIGGGSGGLA A++A + G K ++ LGGTCVNVGC+PKK
Sbjct: 5 TKECDFLVIGGGSGGLATARKASGVYGVKTIAVEAKR---------LGGTCVNVGCVPKK 55
Query: 76 LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKID 135
+ AA + E+IH++ AYG+ V + NW IK +N + +L K++
Sbjct: 56 VTFNAAAIAEAIHDSKAYGFSVET--TAPFNWSYFKNKRDAFIKRLNGIYERNLGNDKVE 113
Query: 136 YVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPD-IPGA 182
Y++G + TL +G+K+ I AK I++AVGGRP P IPGA
Sbjct: 114 YIHGWASLTGKNEAEVTLDDGTKQTIRAKKILLAVGGRPTVPQGIPGA 161
Score = 81.8 bits (193), Expect = 3e-14
Identities = 53/128 (41%), Positives = 76/128 (59%), Gaps = 5/128 (3%)
Query: 230 RSVPLRGFDQQMAQAVTSEMEQKGVVFHNKCVPLSVEKLE-TGQLKARWQNTETQERGED 288
+ +P FD + + VT+E E+ GV H V +EK E TG+L ++++ + ED
Sbjct: 156 QGIPGADFDPMVQETVTNEYERLGVKLHKNSVQTKIEKDEKTGKLTIHYEDSNGKSTLED 215
Query: 289 VFDTVLMATGRYALTKTLNLEAAGVTCVSNSGKIIA-ETEQTNVSNIYAVGDVLEGKPEL 347
V D ++ A GR L L+ AGV + G+IIA E + TNV +IY++GDV+ GK EL
Sbjct: 216 V-DDLIWAIGRSPEVDGLGLDKAGVK-QNERGQIIADEYQNTNVDSIYSLGDVI-GKIEL 272
Query: 348 TPVAIHAG 355
TPVAI AG
Sbjct: 273 TPVAIAAG 280
Score = 44.0 bits (99), Expect = 0.009
Identities = 20/77 (25%), Positives = 41/77 (53%)
Query: 386 GCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVALREAPQRILGLHF 445
G +GL E A+ R+G + ++ Y+ + + + + + + ++++GLH
Sbjct: 282 GSIGLIELEAIERYGKENIKCYNTSFTALYYTMMEPEDKGPTKYKLVCLGPEEKVIGLHI 341
Query: 446 VGPVAGEVIQGFAAAVK 462
+G +GE++QGF AVK
Sbjct: 342 LGLGSGEMLQGFGVAVK 358
>UniRef50_Q8NLD1 Cluster: Dihydrolipoamide dehydrogenase/glutathione
oxidoreductase and related enzymes; n=4; Corynebacterium
glutamicum|Rep: Dihydrolipoamide
dehydrogenase/glutathione oxidoreductase and related
enzymes - Corynebacterium glutamicum (Brevibacterium
flavum)
Length = 448
Score = 113 bits (271), Expect = 1e-23
Identities = 110/393 (27%), Positives = 180/393 (45%), Gaps = 49/393 (12%)
Query: 6 LDTKFKNILAGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGT 65
+DTK L GT ++DL V+G G G A + G KV +++ SPQ GGT
Sbjct: 9 MDTKLGAEL-GT-EFDLIVVGFGKAGKTIAMKRSAAGDKVALIEQ---SPQM----YGGT 59
Query: 66 CVNVGCIP-KKLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWV 124
C+NVGCIP KKL+ + A G+ +AV ++ K+N L A
Sbjct: 60 CINVGCIPTKKLLFETAT-GKDFPDAVVARDQLIG----KLNAKNLAMAT---------- 104
Query: 125 TRVDLREKKIDYVNGLGEFKDAHTLIATLKNGSKKEIT-AKNIVIAVGGRPHYPDIPGAV 183
+K + ++G F +H + T+ +GS + A IVI G P P++PG
Sbjct: 105 ------DKGVTVIDGKATFTASHEI--TVTSGSDTLVLYAPTIVINTGSTPVIPNVPGTD 156
Query: 184 E-YCISSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRS-VPLRGFDQQM 241
+ S I + P ++G G IGLE A + G T++ R +PL+ FD+++
Sbjct: 157 NPHVFDSTGIQHISPLPKHLAIIGGGPIGLEFATLFSGQGSKVTIIDRGELPLKNFDREV 216
Query: 242 AQAVTSEMEQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYA 301
A+ +++E +G+ F N +G L ++ + + D L+A GR
Sbjct: 217 AELAKTDLEARGITFLNNAELTGF----SGDLTIALKDHDL------LADAALLAIGRRP 266
Query: 302 LTKTLNLEAAGVTCVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLAR 360
T L LE AG+ G+++ + +TN+ I+AVGDV G P+ T V+ R++
Sbjct: 267 ATDGLGLEQAGIK-TGTRGEVLVDAHLRTNIDGIFAVGDV-NGGPQFTYVSYDDHRIVLD 324
Query: 361 RMFAGATQPMDYDNVATTVFTPLEYGCVGLSEE 393
++ + + + TT F +G + E
Sbjct: 325 QLAGTGKKSTAHRLIPTTTFIEPPLSTIGDNTE 357
>UniRef50_A6G2P8 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Dihydrolipoamide
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 488
Score = 113 bits (271), Expect = 1e-23
Identities = 100/349 (28%), Positives = 155/349 (44%), Gaps = 20/349 (5%)
Query: 15 AGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPK 74
A T D+A+IG G+ GL +EA++ GA+ V+ + P GT TC VGC+P
Sbjct: 4 ANTIQVDVAIIGAGTAGLVARREALSQGAERVVM--IEGGPLGT------TCARVGCMPS 55
Query: 75 KLMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQN-HIKSVNWVTRVDLREKK 133
KL+ AA ++ H A G + ++I+ A+ VQ+ + +V +
Sbjct: 56 KLLIAAA---DAAHGARVAGQFGVHANDLRIDGEAVMRRVQSERDRFAGFVVDATEALPE 112
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHY-PDIPGAVEYCISSDDI 192
+ G F+DA L L G E+ A+ +VIA G P + + ++++ +
Sbjct: 113 GQLLRGWARFRDATHLEVALNEGGSVEVEARAVVIATGSAAFIPPPLRDLGDRLLTNEGV 172
Query: 193 FSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQK 252
F L P VVG G IGLE L+ LG + + + QA + +
Sbjct: 173 FELPTLPRSVAVVGTGVIGLELGQALDRLGVAVQIFDINTRMPMLSDPGMQAEARAIFEA 232
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERG-EDVFDTVLMATGRYALTKTLNLEAA 311
+ H L ++E G ++ RW+ E + G E FD VL ATGR L L+AA
Sbjct: 233 ELDLHLGVGELEATRVEAG-VQLRWREAEGEGEGREATFDYVLAATGRRPQLGRLGLDAA 291
Query: 312 GVTCVSNSGKIIAETEQTNV---SNIYAVGDVLEGKPELTPVAIHAGRL 357
GV + G + E+T S ++ GDV +P L A GR+
Sbjct: 292 GVE-LDRRGMPVRWDERTGQIGDSALFLAGDVTGFRPLLHEAAAE-GRI 338
>UniRef50_A4MI92 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Geobacter
bemidjiensis Bem|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Geobacter
bemidjiensis Bem
Length = 449
Score = 113 bits (271), Expect = 1e-23
Identities = 121/446 (27%), Positives = 182/446 (40%), Gaps = 33/446 (7%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQA 80
D+ VIG G+ G A G +V V+D P G GTC GC P+K + QA
Sbjct: 6 DVLVIGTGTAGFTLALACRKGGRQVAVVD---DKPYG------GTCGRNGCEPEKYLMQA 56
Query: 81 ALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGL 140
A + + G VP+ ++WPAL + V T ++ I G
Sbjct: 57 AQVVHLTRQMSGQGITVPAA----MDWPALIRSKSAFSNGVPERTERAFQQAGIKMYFGT 112
Query: 141 GEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPPG 200
F T+ GS+ + A+ IVIA G RP D PGA + + D + + P
Sbjct: 113 AHFLSPETVAI----GSETTVRAETIVIATGARPAPLDFPGA-GLVVETSDFMEMKNLPR 167
Query: 201 KTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFHNK 259
+ L +G G + L + G T+L R L+ FD +MAQ +G+
Sbjct: 168 RVLFIGGGCLALSFGHVARAAGADVTILQRGERVLKNFDLEMAQLAAKAARARGINIVTG 227
Query: 260 CVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSNS 319
EK++ G + T+ D+ ++ +GR ++ E AG S
Sbjct: 228 ITAAMAEKVQ-GAFMTYGKGGCTEAFPSDL---IVNTSGRIPDLDPVDPE-AGAVARSAR 282
Query: 320 GKIIAETEQTNVSN--IYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
G + E Q +VSN ++A+GD + L+ VA + A + G + DY V +
Sbjct: 283 GVTVNEFLQ-SVSNPRVWAIGDACDSPYLLSTVADMEAEVAADNILTGNRRRPDYQGVPS 341
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNI-RNCYLKAVALREA 436
VGL+E A AR K + T+ + R I + V + E
Sbjct: 342 MAQAQPPLSFVGLTE--AQARQSGKKFRINRG---STDSWPSSRRIGQQGGFYKVLIEEE 396
Query: 437 PQRILGLHFVGPVAGEVIQGFAAAVK 462
+ILG H +G AGE I FA A+K
Sbjct: 397 TGKILGAHLLGQNAGETINIFALALK 422
>UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component
dihydrolipoamide dehydrogenase; n=2; Bacteria|Rep:
Pyruvate dehydrogenase E3 component dihydrolipoamide
dehydrogenase - Mycoplasma mobile
Length = 600
Score = 112 bits (270), Expect = 2e-23
Identities = 107/452 (23%), Positives = 196/452 (43%), Gaps = 37/452 (8%)
Query: 17 TYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKL 76
T YD+ V+G G GG A+EA G K +++ WG G C+NVGCIP K
Sbjct: 142 TDKYDVIVLGSGPGGYLAAEEAGKNGKKTLIIEK-------EYWG--GVCLNVGCIPTKA 192
Query: 77 MHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDY 136
+ ++ + E + A YG ++ + +K+NW + E Q + ++ ++ K+
Sbjct: 193 LLKSTEVFEQLSHASDYGLDI-DVSKLKMNWKKMQERKQKVVNTLVGGVLALMKGNKVKT 251
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE-----YCISSDD 191
+NG +F A ++ NG E A+NI+IA G + +PG E + I++++
Sbjct: 252 INGEAKFL-APKVVQV--NGEIYE--AENIIIATGSKNRKLTLPGFEEAYKSGFAITAEE 306
Query: 192 IFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP--LRGFDQQMAQAVTSEM 249
+ P + +++G G IG+E A + G TV +++ P + D+ + + ++ ++
Sbjct: 307 AIQIESLPKELVIIGGGVIGIEFAQIFAASGSKVTV-IQNAPTIIPALDEDVIKVLSDKL 365
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
G+ + +EK +T K + +T + + ++++ GR + N +
Sbjct: 366 ISSGIQIVYNAETVKIEK-DTLHYKVNGE-AKTIKASK-----IMVSVGR--IPVIANAK 416
Query: 310 AAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
G +I E QTN+ YA+GDV K L VA + + +
Sbjct: 417 EVGYQIGEKGEIVINEFCQTNIPGAYAIGDV-TFKTMLAHVAYQHAHIAIKHLLGNGDLS 475
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
V ++T E VG+SE A G + H + + + + K
Sbjct: 476 YTGKTVPACIYTHPEIASVGMSERQA-KESGRAYISEKHQMKFIGKAIASDQTMG--FSK 532
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ +E ILG H +G A ++I A+
Sbjct: 533 LIIDKET-HEILGAHIIGAHATDLISELVVAI 563
>UniRef50_Q88W40 Cluster: Glutathione reductase; n=2; Bacilli|Rep:
Glutathione reductase - Lactobacillus plantarum
Length = 449
Score = 111 bits (268), Expect = 3e-23
Identities = 106/380 (27%), Positives = 158/380 (41%), Gaps = 31/380 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
DYD IG G A + KV +++ T + GTC N GC K L+
Sbjct: 3 DYDTIFIGSGHATWHAAVALAHAQHKVAIIEEDT---------IAGTCTNFGCDAKILLD 53
Query: 79 QAALLGESIHEAVAYGWEV-PSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
L E + + G P++D W L Q I+ ++ ++ I +
Sbjct: 54 GPFELTEQLKQYQGIGVNTTPTID-----WSQLMAYKQQVIQPLSVQMTAVFKQLGITII 108
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGH 197
G GE D HT+ + TA IVI G RP IPGA + S D L
Sbjct: 109 TGHGELTDTHTVQV-----ADSTYTADTIVIGTGQRPAKLAIPGA-DLMHDSRDFLDLPT 162
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVVF 256
P + ++GAG I LE A LG ++ L F + + + + ++ GV F
Sbjct: 163 MPKRLTLIGAGIISLEFANMAVLLGSEVHIIEFADRALPAFYSEHVKKMITHLQAAGVHF 222
Query: 257 HNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCV 316
H V K TG + + + D ++ ATGR + L L G+
Sbjct: 223 HFGEALSQVTKTATGLMATTASGLKIES------DDIIAATGRIPNIEHLGLTKVGIK-T 275
Query: 317 SNSGKIIAETEQTNVSNIYAVGDVL-EGKPELTPVAIHAGRLLARRMFAGATQPMDYDNV 375
G I+ + +T++ NIYA GDV+ + P+LTP AI +A ++ G+T +DY +
Sbjct: 276 DRHGIIVDDHLRTSIPNIYASGDVISKTLPKLTPTAIFESNYIAGQLL-GSTAAIDYPVI 334
Query: 376 ATTVFTPLEYGCVGLSEETA 395
VFT VG+S E A
Sbjct: 335 PAVVFTLPRIAQVGVSVEAA 354
>UniRef50_A6CEV1 Cluster: Glutathione reductase; n=1; Planctomyces
maris DSM 8797|Rep: Glutathione reductase - Planctomyces
maris DSM 8797
Length = 449
Score = 111 bits (268), Expect = 3e-23
Identities = 111/449 (24%), Positives = 179/449 (39%), Gaps = 34/449 (7%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
+D+ ++G G A++ +V V+D +GGTC GC PKK++
Sbjct: 3 FDILILGSGPAATRIAEQCAER-YQVAVID---------SQEIGGTCALHGCNPKKVLVH 52
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNG 139
AA L + + G + INW L + K V ++K I G
Sbjct: 53 AAELVDRTRRSK--GQLIDDNSRASINWSQLIAFKETFTKPVTSQKTKKFKKKNISIFQG 110
Query: 140 LGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIFSLGHPP 199
F T+ +G+ E+ + IVI G RP I G + SD P
Sbjct: 111 EARFTGLKTIEV---DGA--ELEGEKIVICTGARPAPLKITGE-DLITHSDQFLQCNRLP 164
Query: 200 GKTLVVGAGYIGLECAGFLNSLGYPATVLVRSV-PLRGFDQQMAQAVTSEMEQKGVVFHN 258
+ + +G GYI E A G TV+ + PL GF+ + + + G+ F
Sbjct: 165 AELIFIGGGYISFEFAHVAQRAGSAVTVMDHNEQPLSGFEPSLVERLVDYSRTLGIEFAL 224
Query: 259 KCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
S+ K + +L+ + Q+ E D V+ GR T+ L+LE A V
Sbjct: 225 SSNVQSLVKNKNRKLQLTAKQKGMQK--EYFADMVVHGAGRVPATEGLDLEQAAVEYDEK 282
Query: 319 SGKIIAETEQTNVSNIYAVGDVLE-GKPELTPVAIHAGRLLARRMFAGATQPMDYDNVAT 377
K+ + + ++IYA GDV++ +P+LTPVA + + + G DY V
Sbjct: 283 GIKVNQFMQSISNAHIYAAGDVVDTDQPKLTPVANQQAYTVVKNIIEGNHATPDYGVVPR 342
Query: 378 TVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIR----NCYLKAVAL 433
+F+ + VG+ E A E + F T+ ++R C + +
Sbjct: 343 VLFSVPQLASVGMDE--------AQASEAGYDFKVQTDDMSSWGSLRKVGVTCAAYKILI 394
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
++LG H + P A E I FA +K
Sbjct: 395 ERQTDQVLGAHLLAPDAAETINLFALGMK 423
>UniRef50_A7D615 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyridine
nucleotide-disulphide oxidoreductase dimerisation region
- Halorubrum lacusprofundi ATCC 49239
Length = 496
Score = 111 bits (268), Expect = 3e-23
Identities = 123/462 (26%), Positives = 198/462 (42%), Gaps = 41/462 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP-KKLM 77
++D VIG GSG L A G V +++ +G LGGTC+N GCIP KKL+
Sbjct: 12 EFDFLVIGSGSG-LDVANAMAGQGNSVAIVE------EGR---LGGTCLNRGCIPSKKLL 61
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKI-DY 136
+ A ++ +++ A + + + +++ + V + + R L D
Sbjct: 62 YHADVM-KTVQRAGEFDIDA---EVNGVDFAEIVRTVNEDVSGSSESIRKGLTSSDAHDL 117
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGA--VEYCISSDDIFS 194
+G G F D T+ + + A ++IA G RP P I G V+Y ++S +
Sbjct: 118 FSGTGRFVDDRTVEIVDGDDEGATLRADTVLIATGTRPSIPPIDGIEDVDY-LTSTEALR 176
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKG 253
L P ++VG GYI E F + G T++ R L D+ + +A T +
Sbjct: 177 LETAPDHLVIVGGGYIAAELGHFFGTFGSDVTIVGRRENLLPEADEAVGEAFTDRYADRF 236
Query: 254 VVFHN-KCV-------PLSVEKL---ETGQLKARWQNTETQERGEDVF---DTVLMATGR 299
V+ + V ++VE E ++A + E EDV D +L+A GR
Sbjct: 237 DVYSGYEAVAADESGGEVTVEARPYPEAESVRAGGETVGAPEDAEDVTVAGDALLVAAGR 296
Query: 300 YALTKTLNLEAAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLA 359
T LNL+A GV ++ E QT+ ++A+GDV+ G+ L A H R +
Sbjct: 297 RPNTDALNLDATGVETDADGFVETDEYLQTDAEGVWALGDVV-GEYLLKHSANHEARAVI 355
Query: 360 RRMFAGATQPMDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIP 419
R + +P+DY + VF E VG E+ L A+ +A Y T
Sbjct: 356 RNLLGDEPEPVDYSAMPFAVFASPEVAGVGAREQD-LRESDAEYATRTYA-YDET----A 409
Query: 420 QRNIRNCYLKAVALREAPQRILGLHFVGPVAGEVIQGFAAAV 461
+ + + L + I G H VGP A +I+ A+
Sbjct: 410 RGSAMHAEGFVKVLIDLDGNIEGCHIVGPEASNLIEEVVVAM 451
>UniRef50_Q9YBZ2 Cluster: Mercuric reductase; n=1; Aeropyrum
pernix|Rep: Mercuric reductase - Aeropyrum pernix
Length = 461
Score = 110 bits (265), Expect = 7e-23
Identities = 122/453 (26%), Positives = 183/453 (40%), Gaps = 46/453 (10%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
+YD+ VIGGG+ G + A GA V + V+ P LGGTCVN GC+P K
Sbjct: 5 EYDIIVIGGGAAGFSAVVAAAEGGASVLL---VSEGP------LGGTCVNFGCVPSK--- 52
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK-IDYV 137
H V Y +KI+ E + +++ L + +DY+
Sbjct: 53 ---------H--VLYNLSTARKAGLKISLSEALEGARKVSETLRKEKYESLLDSLGVDYL 101
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-----CISSDDI 192
G FK + A ++ K +IAVG R P IPG E + ++ +
Sbjct: 102 RGRARFKAPGIVEAD----GREVRYRKAAIIAVGARTWRPPIPGLKEAEKAGRILDNERL 157
Query: 193 FSLGHPPG--KTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSE-M 249
F G PP V+G G+E A G +L RS L D+ A +
Sbjct: 158 FGEGPPPDMESVAVIGGRAQGVEAAQIFARSGLKTVLLQRSGRLLPRDEPEAGVYMKRVL 217
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
E GV PL VE + G ++ ++ + E + + +ATGR + L LE
Sbjct: 218 EGDGVEVRTSARPLRVESVR-GAVRIDYETPQGPASVEASY--IYLATGRKPVLDGLGLE 274
Query: 310 AAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
GV VS+ G I+ + +YA GD + G +L PVA G + A G +
Sbjct: 275 NVGVR-VSSDGFIVVNEKLMASPGVYAAGDCIGGI-QLEPVAAREGYVAALNALGGNVE- 331
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLK 429
MDY + VFT E+ VGL+E + G P + ++K
Sbjct: 332 MDYTVIPRAVFTDPEFASVGLTERELARKLGVCACRTVDITQIPRARIM---GYETGFVK 388
Query: 430 AVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
V + +++ G+H + P A E I A +K
Sbjct: 389 MV-VDPRTKKVAGVHMMAPQAAEAIHEAAFILK 420
>UniRef50_A2F0F6 Cluster: Dihydrolipoyl dehydrogenase; n=2;
Trichomonas vaginalis G3|Rep: Dihydrolipoyl
dehydrogenase - Trichomonas vaginalis G3
Length = 471
Score = 110 bits (264), Expect = 9e-23
Identities = 119/455 (26%), Positives = 194/455 (42%), Gaps = 34/455 (7%)
Query: 15 AGTYDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPK 74
A T + DL VIGGG GG A A A LG K ++ + +GGTC+ GCIP
Sbjct: 8 AFTQNPDLLVIGGGPGGYAAAIRAAKLGLKTVCVE--------KEKLMGGTCLREGCIPS 59
Query: 75 K-LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK 133
K ++ + + E+ HE +G ++P A+ + A+ + +N I + L ++
Sbjct: 60 KFFLNMSHKVYEANHEFKNFGIKLPGEAAVDM---AIAQRRKNGILAGLSAGIEGLIDRA 116
Query: 134 -IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYP-DIPGAVEYCISSDD 191
+ V+G + + L++G KN+++A G +P P + +S
Sbjct: 117 GGELVHGTATINSKNDVSVKLEDGKTVIFNPKNLLLATGTDKWFPKTFPVDEQIIATSQG 176
Query: 192 IFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRG--FDQQMAQAVTSEM 249
+ + P VVG G IGLE +SLG T++ + + G D + + V + +
Sbjct: 177 VLNWKEIPKTLTVVGGGIIGLELGSVFHSLGSKVTIVDMAPTIGGPSVDPMIGRYVQNIL 236
Query: 250 EQKGVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLE 309
+++G+ F S K E G ER L+A GR LE
Sbjct: 237 KRRGMDFILGKGVDSCTKTENGVEVVVGDKKLQSER-------ALIAIGRRLHLDGFGLE 289
Query: 310 AAGVTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQP 369
+ N + +T+ N+YA+GD++ G P+L A G + M AG
Sbjct: 290 RLNLKRQKNGLIEVNNRLETSEKNVYAIGDIVPG-PQLAHKAEEEG-IACVEMLAGHESS 347
Query: 370 MDYDNVATTVFTPLEYGCVGLSEETALARHGADKVEV--YHAFYKPTEFFIPQRNIRNCY 427
D + + ++T E VGL++ A + KV + Y A + P +
Sbjct: 348 YDPNVIPAVIYTSPEIATVGLTQNKAAKQGIKTKVGMFPYSANSRARAILDP-----TGF 402
Query: 428 LKAVALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+K V + R+LG+ VGP AGE I A A+K
Sbjct: 403 VKFVCGEDG--RVLGMQIVGPNAGEAIMEGAIAIK 435
>UniRef50_A7IAT2 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase; n=1; Candidatus
Methanoregula boonei 6A8|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase - Methanoregula
boonei (strain 6A8)
Length = 448
Score = 110 bits (264), Expect = 9e-23
Identities = 96/373 (25%), Positives = 162/373 (43%), Gaps = 25/373 (6%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQAA 81
+ V+GGG G + + G KVT+++ P+G + G+GG C++ GC+P ++ AA
Sbjct: 2 IVVLGGGPAGRIASIRLASAGKKVTLVE-----PKGKEQGIGGQCLHFGCMPVCALNDAA 56
Query: 82 LLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGLG 141
+ + G + +L A + L + + ++ + + R+ +D V G
Sbjct: 57 RIAATTRRFYKRGM-IDTLPAFRFG--KLMDETYVVQQKISGILDDETRQAGVDVVYGKA 113
Query: 142 EFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG-AVEYCISSDDIFSLGHPPG 200
D + + + + +IA G RP+ P IPG ++ + ++SL P
Sbjct: 114 GRVDGRQVFI-----GDEPVDCEAAIIATGSRPNIPAIPGVSLPGVYTPHTLWSLRELPK 168
Query: 201 KTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFHNKC 260
K ++G + E A + G TVL RS L+ D+ + E+ + +
Sbjct: 169 KIAIIGGSVMAAEFAYIFSEFGSEVTVLARSGFLKNLDRHLRAVAMKELSGVNIQEETEV 228
Query: 261 VPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSNSG 320
++ L TG R++ T ER D VL+A G L + G+ +
Sbjct: 229 AGIAGTDLTTG---VRYRAAGT-ERAISA-DAVLLAAG---LVPNSGM-VTGIDKGPDGA 279
Query: 321 KIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYDNVATTVF 380
I+ + QT+V IYA GDV G P LTPVA H G ++A G + MDY + ++
Sbjct: 280 IIVNDRMQTSVPGIYACGDV-AGAPFLTPVARHEG-IVAADNILGKERHMDYSRIPQAIY 337
Query: 381 TPLEYGCVGLSEE 393
E G S E
Sbjct: 338 LAHELAFCGSSGE 350
>UniRef50_Q8VPK7 Cluster: Dihydrolipoamide dehydrogenase; n=43;
Streptococcus|Rep: Dihydrolipoamide dehydrogenase -
Streptococcus pneumoniae
Length = 567
Score = 109 bits (261), Expect = 2e-22
Identities = 115/451 (25%), Positives = 203/451 (45%), Gaps = 43/451 (9%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIP-KKLMH 78
+D+ VIGGG G A +A G KV +++ K LGGTC+N GCIP K +H
Sbjct: 112 FDIVVIGGGPAGYVAAIKAAQFGGKVALVE---------KSELGGTCLNRGCIPTKTYLH 162
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
A ++ E+I A G + + + ++ L E + ++ LR +
Sbjct: 163 NAEII-ENIGHAANRGIVIENPN-FTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHK 220
Query: 139 GLGEF-KDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE-YCISSDDIFSLG 196
G+G KD + L+ NGS+ + K I++A G + + ++PG ++SDDI +
Sbjct: 221 GIGTITKDKNVLV----NGSEL-LETKKIILAGGSKVNKINVPGMESPLVMTSDDILEMN 275
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVLV---RSVPLRGFDQQMAQAVTSEMEQKG 253
P +++G G +G+E + G TV+ R VP D ++++ + +E+KG
Sbjct: 276 EVPESLVIIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVP--AMDVEVSKNLRLILERKG 333
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG- 312
+ + + E GQL+ + + + + + L++ GR +LE G
Sbjct: 334 MTILTGTKLQEIIE-ENGQLRIK-----VEGKDDIIASKALLSIGRMP-----DLEGIGE 382
Query: 313 VTCVSNSGKI-IAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMD 371
V + G I + E +T+V IYA GD+ G L A G + A G
Sbjct: 383 VEFELDRGCIKVTEYMETSVPGIYAPGDI-NGTKMLAHAAFRMGEVSAENALKGNHAVAK 441
Query: 372 YDNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAV 431
+ ++T E VGL+EE A ++ V + + I + ++K +
Sbjct: 442 LNLTPAAIYTLPEVAAVGLTEEQAREKY---DVAIGKFNFAANGRAIAS-DAAQGFVKVI 497
Query: 432 ALREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
A ++ + ILG+H +GP A E+I ++ ++
Sbjct: 498 ADKKYGE-ILGVHIIGPAAAELINEASSIIE 527
>UniRef50_Q18CC1 Cluster: E3 component of acetoin dehydrogenase
enzyme system; n=2; Clostridium difficile|Rep: E3
component of acetoin dehydrogenase enzyme system -
Clostridium difficile (strain 630)
Length = 576
Score = 109 bits (261), Expect = 2e-22
Identities = 117/446 (26%), Positives = 199/446 (44%), Gaps = 37/446 (8%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+DYD+ VIGGG GG A +A LG +V +++ LGGTC+N GCIP K
Sbjct: 122 HDYDVVVIGGGPGGYLSALKAALLGGRVALVEENI---------LGGTCLNRGCIPTKTY 172
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYV 137
+ A + E I + G +V ++D + A+ + +K + L+ + +D
Sbjct: 173 IKTAEILEEIDQLSKRGVKV-TVDKEQDIKKAI-KYKNRVVKKLTAGVGGLLKSRDVDVF 230
Query: 138 NGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPG-AVEYCISSDDIFSLG 196
N K+ H +I L +G K + +NI+IA G + I G I+S + L
Sbjct: 231 NLKASVKEEHKVI--LSDG--KVLDTENIIIATGSKVRILPIKGIESNLIITSTEALDLE 286
Query: 197 HPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVTSEMEQKGVV 255
P + +++G G IG E A NS G T++ + + D+++++++ + +KG+
Sbjct: 287 TVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSESLKYSLSKKGIN 346
Query: 256 FHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEA-AGVT 314
+ K + + K N GE+ L YA+ + NL +
Sbjct: 347 V--------LTKKKVSEFKEEGNNILVCIEGEEPIKADLCL---YAIGREANLSGIEDLD 395
Query: 315 CVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ G I+ ++ +T++ +IYAVGDV G L A G + A G + +D
Sbjct: 396 IKIDKGSIVVNSKMETSIPSIYAVGDV-TGGVMLAHAAFKMGEVAASNAL-GVNKEVDLG 453
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVAL 433
+ + V+T E VG++EE A ++ KV ++ Q Y+K VA
Sbjct: 454 ALPSCVYTIPEVASVGITEEDARKKYNV-KVGKFNFAGNGRALASGQ---EQGYVKVVAD 509
Query: 434 REAPQRILGLHFVGPVAGEVIQGFAA 459
+ + ILG+H G E+I A+
Sbjct: 510 AKYGE-ILGIHMFGCGVAELINHAAS 534
>UniRef50_A1W7R7 Cluster: Dihydrolipoamide dehydrogenase; n=58;
Bacteria|Rep: Dihydrolipoamide dehydrogenase -
Acidovorax sp. (strain JS42)
Length = 627
Score = 109 bits (261), Expect = 2e-22
Identities = 118/406 (29%), Positives = 191/406 (47%), Gaps = 52/406 (12%)
Query: 21 DLAVIGGGSGGLACAKEAVNLGAKVTVLD-YVTPSPQGTKWGLGGTCVNVGCIPKK-LMH 78
D+ V+GGG GG + A A +LG V +++ Y T LGG C+NVGCIP K L+H
Sbjct: 132 DVLVLGGGPGGYSAAFRAADLGLNVVLVERYAT---------LGGVCLNVGCIPSKALLH 182
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
AA++ E H A G + A ++N L + I + + +K+ +
Sbjct: 183 VAAVMDEVSHLKSA-GID---FGAPQVNIHTLRGHKEKVIGKLTGGLAQMAKMRKVTVLR 238
Query: 139 GLGEFKDAHTL-------IATLKNGSKKEITAKNIVIAVGGR----PHYPDIPGAVEYCI 187
G G F A+ L + K G+KK + K +IA G + P PD P V+
Sbjct: 239 GYGHFVGANHLEVEETTGTSQDKTGAKKVVAFKRAIIAAGSQAVRLPFMPDDPRVVD--- 295
Query: 188 SSDDIFSLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVL-VRSVPLRGFDQQMAQAVT 246
S +L P + L++G G IGLE ++LG V+ + ++G D+ + + V
Sbjct: 296 -STGALALKDVPKRMLILGGGIIGLEMGTVYSTLGARLDVVEMLDGLMQGADRDLVK-VW 353
Query: 247 SEMEQK---GVVFHNKCVPLSV--EKLETGQLKARWQNTETQERGEDVFDTVLMATGRYA 301
+M Q V+ + K V E ++ A+ T + + V+D VL A GR
Sbjct: 354 QKMNQHRFDNVMLNTKTVAAEATPEGIKVSFAPAKDGVTVPEPQ---VYDLVLQAVGRTP 410
Query: 302 LTKTLNLEAAGVTCVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLAR 360
K + + AGV V++ G I + + +TNV +I+A+GD++ G+P L A+H +A
Sbjct: 411 NGKKIAADKAGVA-VTDRGFINVDIQMRTNVPHIFAIGDIV-GQPMLAHKAVHEAH-VAA 467
Query: 361 RMFAG--------ATQPMDYDNVATTVFTPLEYGCVGLSEETALAR 398
+ AG A+ + + + +T E VGL+E+ A A+
Sbjct: 468 EVIAGELQGNKELASAAFNARVIPSVAYTDPEVAWVGLTEDQAKAQ 513
>UniRef50_A7HGF8 Cluster: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region; n=2;
Anaeromyxobacter|Rep: Pyridine nucleotide-disulphide
oxidoreductase dimerisation region - Anaeromyxobacter
sp. Fw109-5
Length = 456
Score = 108 bits (260), Expect = 3e-22
Identities = 121/450 (26%), Positives = 184/450 (40%), Gaps = 36/450 (8%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMH 78
D D VIG G G+ A G KV + + + LGGTC+N GC P K +
Sbjct: 2 DLDAIVIGSGQAGVPLATRLAKHGRKVLLAE---------RADLGGTCINTGCTPTKTLV 52
Query: 79 QAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVN 138
+A A G V D++ +++PA+ ++ W + + + D
Sbjct: 53 ASARAAHVARSARRLGVRV---DSVAVDFPAVIARKDAIVR--RW--QEGIARRLADAGE 105
Query: 139 GLGEFKDAHTLIA--TLKNGSKKEITAKNIVIAVGGRPHYPDIP--GAVEYCISSDDIFS 194
L + L+ T++ ++ A +++ VGGRP P IP G V + + + +
Sbjct: 106 NLRLVRGEARLVGERTVEIAGERH-RAATVILNVGGRPIEPPIPGLGGVPW-LDNRRVME 163
Query: 195 LGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRG-FDQQMAQAVTSEMEQKG 253
L P +VVG GYIG E A G TV+ L G D ++++A+ +G
Sbjct: 164 LPELPSHLVVVGGGYIGCELAQAYRRFGADVTVIEPGKHLLGNGDPEVSEAIEGVFRDEG 223
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
V +V + + G+L R T +L+ATGR T L EAAGV
Sbjct: 224 VALLLDARAEAVSR-DGGRLTVRLSTGRTVTGSH-----LLVATGRRPNTDDLGAEAAGV 277
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ + +++ IYAVGD G P+ T A RLL + +
Sbjct: 278 KLDGRGFVEVDDHYRSSAPGIYAVGD-CAGGPQFTHAAWDDHRLLFDVLMGKPGRGRKDR 336
Query: 374 NVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQ-RNIRNCYLKAVA 432
V T +T + VGL+E A D+ Y P E L +
Sbjct: 337 LVPYTAYTDPQVAGVGLTERAA-----RDQGVEYEVATLPFENIARAIETDEKAGLLKIL 391
Query: 433 LREAPQRILGLHFVGPVAGEVIQGFAAAVK 462
+ A +RILG VG AGE+I FAA ++
Sbjct: 392 VDPATERILGASIVGAEAGELIHVFAALMQ 421
>UniRef50_A5FRC9 Cluster: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase precursor; n=3;
Dehalococcoides|Rep: FAD-dependent pyridine
nucleotide-disulphide oxidoreductase precursor -
Dehalococcoides sp. BAV1
Length = 489
Score = 108 bits (260), Expect = 3e-22
Identities = 99/387 (25%), Positives = 168/387 (43%), Gaps = 24/387 (6%)
Query: 18 YDYDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLM 77
+ YDL VIG G G A LG KV +++ K LGG C C+P K +
Sbjct: 3 FQYDLVVIGSGLAGFTSTVFANGLGKKVAMVE---------KGKLGGACTWNACVPSKTL 53
Query: 78 HQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKK-IDY 136
Q +G + + Y L ++ + + + + ++ ++ V D EK I+
Sbjct: 54 LQ---IGRRVGQIKKYNQNGLKLVSVNLQTENIMPYLHSVLEDISGVDDFDNLEKTGINI 110
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEY-CISSDDIFSL 195
+ G F D H + NG + ++AK+ +IA G P P + G + +++ +F +
Sbjct: 111 LKGEAVFTDRHHISL---NG--QVVSAKHFIIATGSSPAIPPVEGLADIPYYTNETVFDI 165
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEM--EQKG 253
P +V+G G G+E LG ++ + + D + + ++
Sbjct: 166 KSIPSSMIVLGGGPAGIELGLAFAWLGCKVDIIEMAERILPKDDTELSGLLLDYLNAEEN 225
Query: 254 VVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
+ H + ++ + GQLK Q T + E +TVL+A GR A L LE AGV
Sbjct: 226 LQIHVSTKAIRFQEQDNGQLKLEMQ-TREGKINEITAETVLVAVGRRANVAGLALEKAGV 284
Query: 314 TCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDYD 373
+ G + QT+ NI+A GDV G +L +A L A Q + YD
Sbjct: 285 KYTAR-GISVNSKLQTSSLNIFAAGDV-AGPIQLGMMAEKQAILAASNACLPFKQSIRYD 342
Query: 374 NVATTVFTPLEYGCVGLSEETALARHG 400
+VA ++ + +GL+E+ A ++G
Sbjct: 343 DVAWVTYSEPQMAHIGLTEDEARRKYG 369
>UniRef50_Q6L2F3 Cluster: Mercuric reductase; n=3;
Thermoplasmatales|Rep: Mercuric reductase - Picrophilus
torridus
Length = 446
Score = 108 bits (260), Expect = 3e-22
Identities = 110/380 (28%), Positives = 174/380 (45%), Gaps = 43/380 (11%)
Query: 19 DYDLAVIGGGSGGLACAKEAVNL---GAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK 75
DYDL +IG G+ G A A A L G ++ ++ LGGTCVNVGC+P K
Sbjct: 3 DYDLGIIGWGAAGFAAAIRASELTYNGMRIALIG---------NGDLGGTCVNVGCVPSK 53
Query: 76 LMHQAALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHI-KS-VNWVTRVDLREKK 133
+ +A+ + + A+ + S A +N+ L ++++ + KS N T V
Sbjct: 54 YLIEAS---KEYNHALKPRYPGISSSA-GVNFHELMSSLRSFVLKSRENKYTNVIKNFHN 109
Query: 134 IDYVNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVEYCISSDDIF 193
ID G F + ++ N K I A N +IA G RP+ IP ++ I+SDD++
Sbjct: 110 IDLYRGKASFISKNEVMV---NNIK--IRATNFIIATGSRPY---IPENIKNYITSDDLW 161
Query: 194 SLGHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRS-VPLRGFDQQMAQAVTSEMEQK 252
SL P + ++G+G + +E A ++ G V RS L+ FD + + + M+
Sbjct: 162 SLDEIPKRLAIIGSGAVAMEMAYAFSNFGSDVYVFNRSNHVLKNFDSDINKMLIDHMKGL 221
Query: 253 GVVFHNKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAG 312
GV K G +K + +R FD +L AT R +NLEAA
Sbjct: 222 GV------------KFIFGDIKEADHDYVISDRKYSGFDKILAATSRVP-NIDINLEAAS 268
Query: 313 VTCVSNSGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
V +G I+ + +T+ IYA GD ++ + +L +A G ++A G + +D
Sbjct: 269 VD--YKNGIIVDDHLRTSNKMIYAAGDCVDQRFQLETLAGREG-VIAVENILGLDRSIDL 325
Query: 373 DNVATTVFTPLEYGCVGLSE 392
NV VFT G +E
Sbjct: 326 INVPWAVFTEPNVASTGYTE 345
>UniRef50_P57303 Cluster: Dihydrolipoyl dehydrogenase; n=10;
Bacteria|Rep: Dihydrolipoyl dehydrogenase - Buchnera
aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon
pisumsymbiotic bacterium)
Length = 473
Score = 108 bits (260), Expect = 3e-22
Identities = 119/452 (26%), Positives = 200/452 (44%), Gaps = 41/452 (9%)
Query: 22 LAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKK-LMHQA 80
+ VIG G G + A +LG +++ LGG C+NVGCIP K L+H A
Sbjct: 9 VVVIGSGPAGYSAAFRCADLGLDTVLIERYDK--------LGGVCLNVGCIPSKTLLHIA 60
Query: 81 ALLGES--IHEAVAYGWEVPSLDAIKI-NWPA-LTEAVQNHIKSVNWVTRVDLREKKIDY 136
++ E+ +H+ + P +D KI NW + + + + S+ +++KI
Sbjct: 61 KVIKEAKELHKT-GVSFNKPDIDIKKIKNWKQHIVNKLTDGLSSMR-------KKRKIRI 112
Query: 137 VNGLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSL 195
G F+ +L T K I N +IA G +P P IP S D SL
Sbjct: 113 FQGHAIFETDKSLCVT-NTEDKFTIFFDNAIIATGSKPIKIPSIPHDDIRIWDSTDALSL 171
Query: 196 GHPPGKTLVVGAGYIGLECAGFLNSLGYPATVLVR-SVPLRGFDQQMAQAVTSEMEQKGV 254
P L++G+G IGLE A ++LG ++ R + L D+ ++ + Q+
Sbjct: 172 KKIPNNFLIIGSGIIGLEMATIYSALGSKVDIIDRFNHFLPVIDEDISSIYKKSINQQ-- 229
Query: 255 VFHNKCVPLSVEKLETGQLKARWQNT-ETQERGEDVFDTVLMATGRYALTKTLNLEAAGV 313
N + ++K+E + E + ++D VL+A GR +L L+ G+
Sbjct: 230 --FNLMLNTHIDKVEVKKDALIVDMIHENIPKKNILYDAVLVAIGRTPNIDSLGLDRIGL 287
Query: 314 TCVSNSGKIIAETE-QTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMFAGATQPMDY 372
++N G I + +TN+ +IYA+GDV G P L +H G +A + +G +
Sbjct: 288 K-INNFGFIQVNNQLKTNIPHIYAIGDV-AGTPMLAHKGVHEGH-IAAEVISGKNHYFEP 344
Query: 373 DNVATTVFTPLEYGCVGLSEETALARHGADKVEVYHAFYKPTEFFIPQRNIRNCYLKAVA 432
+ + +T E VGLSE+ A + +V ++ + + I NC +
Sbjct: 345 KVIPSIAYTDPEIAWVGLSEKEAKQENINYEVAIFP--WNASGRAIAS----NCSIGKTK 398
Query: 433 L--REAPQRILGLHFVGPVAGEVIQGFAAAVK 462
L + +I+G VG AGE+I A++
Sbjct: 399 LIFNKQNNKIIGGSIVGSNAGELIGEVGLAIE 430
>UniRef50_Q041G8 Cluster: Acetoin/pyruvate dehydrogenase complex, E3
component, dihydrolipoamide dehydrogenase; n=3;
Lactobacillus|Rep: Acetoin/pyruvate dehydrogenase
complex, E3 component, dihydrolipoamide dehydrogenase -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 443
Score = 107 bits (258), Expect = 5e-22
Identities = 105/378 (27%), Positives = 166/378 (43%), Gaps = 38/378 (10%)
Query: 24 VIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQAALL 83
+IG G GG AK +V V++ + K GGTC+N+ C+P K + A
Sbjct: 8 IIGFGKGGKTLAKFLAQKSEEVLVIE------KSNKM-YGGTCINIACLPSKRLIIEAAN 60
Query: 84 GESIHEAVAYGWEVPSLDAIKINWPALTEAVQNHIKSVNWVTRVDLREKKIDYVNGLGEF 143
G S +AV+ E+ + +++ N+ D E+ + ++G F
Sbjct: 61 GVSYVDAVSGKNEMTA-----------------QLRNKNYHMLAD--EQTVTVLDGEAHF 101
Query: 144 KDAHTLIATLKNGSKKEITAKNIVIAVGGRPHYPDIPGAVE--YCISSDDIFSLGHPPGK 201
H + L NG K++ + I I G P IPG E Y + S P
Sbjct: 102 IADHEIEVVLTNGKKEQFKGERIFINTGAVPVMLPIPGLKESKYILDSTQAMDEKKMPEN 161
Query: 202 TLVVGAGYIGLECAGFLNSLGYPATVLVRSVP-LRGFDQQMAQAVTSEMEQKGVVFHNKC 260
++GAGYIGLE A G TVL S L D ++Q V ++E GV F
Sbjct: 162 LTIIGAGYIGLEFASMFAKYGSKVTVLDHSREFLSREDDDISQLVKKDLEDAGVHFE--- 218
Query: 261 VPLSVEKL--ETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVSN 318
+ +E++ E + K R+Q QE+ E + +L ATGR + L LE +
Sbjct: 219 LGADIEEIIDEENEAKVRYQ-INGQEK-EISANRILAATGRKPNIENLGLENTSIEITDR 276
Query: 319 SGKIIAETEQTNVSNIYAVGDVLEGKPELTPVAIHAGRLLARRMF-AGATQPMDYDNVAT 377
+ + +T V N++A+GDV +G + T +++ R++ ++F GA D V
Sbjct: 277 GAIKVDDFLRTTVDNVWAIGDV-KGGLQFTYISLDDFRIIKDQLFGTGARMISDRKVVPY 335
Query: 378 TVFTPLEYGCVGLSEETA 395
+VF VGL+E+ A
Sbjct: 336 SVFISPALSQVGLNEKQA 353
>UniRef50_A6DK63 Cluster: Dihydrolipoamide dehydrogenase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Dihydrolipoamide
dehydrogenase - Lentisphaera araneosa HTCC2155
Length = 460
Score = 107 bits (258), Expect = 5e-22
Identities = 98/331 (29%), Positives = 146/331 (44%), Gaps = 20/331 (6%)
Query: 20 YDLAVIGGGSGGLACAKEAVNLGAKVTVLDYVTPSPQGTKWGLGGTCVNVGCIPKKLMHQ 79
YD+ +IG G+ GL + A GA+ V+ + P GT TC VGC+P KL+
Sbjct: 4 YDVIIIGAGTAGLNARRAAKANGAEKVVM--IDGGPLGT------TCARVGCMPSKLLIS 55
Query: 80 AALLGESIHEAVAYGWEVPSLDAIKINWPALTEAVQ-NHIKSVNWVTRVDLREKKIDYVN 138
AA + +A +G E +N A+ E V+ + V +V + + +
Sbjct: 56 AANANYGVTKARMFGIETQEP---VVNDKAVLERVRFERDRFVGFVMEGIDNVPEGELIR 112
Query: 139 GLGEFKDAHTLIATLKNGSKKEITAKNIVIAVGGRP-HYPDIPGAVEYCISSDDIFSLGH 197
EF D HT+ K + +TA V+AVG RP H P + GA + +SSD IF +
Sbjct: 113 EYAEFIDDHTV----KLSGGRILTADKFVLAVGSRPRHVPILDGAEDLILSSDHIFEIES 168
Query: 198 PPGKTLVVGAGYIGLECAGFLNSLGYPATVLVRSVPLRGFDQQMAQAVTSEMEQKGVVFH 257
P V G G IGLE L+ LG + RS + G + ++ +
Sbjct: 169 IPKSVAVFGPGVIGLELGQALSRLGADVRLFGRSGSIGGIQDPEIREYATKTFAEEFYTD 228
Query: 258 NKCVPLSVEKLETGQLKARWQNTETQERGEDVFDTVLMATGRYALTKTLNLEAAGVTCVS 317
K SV K E G+ +++ E Q + E+ FD +L A+GR + T L LE V
Sbjct: 229 TKATIHSVRK-ENGKAIISYEHKE-QGKIEESFDFILTASGRVSNTDRLKLENTSVQVNG 286
Query: 318 NSGKIIAE-TEQTNVSNIYAVGDVLEGKPEL 347
I E T Q ++ + GD + P L
Sbjct: 287 RGTPIYNERTMQCGDTHFFIAGDANDDIPLL 317
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.136 0.405
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 523,956,270
Number of Sequences: 1657284
Number of extensions: 22624018
Number of successful extensions: 62313
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 456
Number of HSP's successfully gapped in prelim test: 533
Number of HSP's that attempted gapping in prelim test: 59246
Number of HSP's gapped (non-prelim): 1680
length of query: 462
length of database: 575,637,011
effective HSP length: 103
effective length of query: 359
effective length of database: 404,936,759
effective search space: 145372296481
effective search space used: 145372296481
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 74 (33.9 bits)
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