Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002806-TA|BGIBMGA002806-PA|IPR001406|tRNA pseudouridine
synthase
(241 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D571F8 Cluster: PREDICTED: similar to CG7042-PA;... 114 2e-24
UniRef50_Q29EU3 Cluster: GA20054-PA; n=2; Diptera|Rep: GA20054-P... 108 1e-22
UniRef50_Q7Q194 Cluster: ENSANGP00000013201; n=2; Culicidae|Rep:... 106 6e-22
UniRef50_UPI0000DB6E84 Cluster: PREDICTED: similar to CG7042-PA;... 105 1e-21
UniRef50_UPI00015B44A3 Cluster: PREDICTED: similar to CG34140-PA... 102 9e-21
UniRef50_Q6GQ53 Cluster: Pseudouridylate synthase; n=4; Euteleos... 79 8e-14
UniRef50_Q8N0Z8 Cluster: tRNA pseudouridine synthase-like 1; n=1... 74 3e-12
UniRef50_Q4SXZ4 Cluster: Chromosome undetermined SCAF12265, whol... 72 2e-11
UniRef50_UPI0000E482DE Cluster: PREDICTED: similar to MGC80334 p... 69 8e-11
UniRef50_Q1FLK6 Cluster: Pseudouridylate synthase; n=1; Clostrid... 59 9e-08
UniRef50_Q28LN3 Cluster: Pseudouridylate synthase; n=15; Alphapr... 59 1e-07
UniRef50_A1WAT5 Cluster: Pseudouridylate synthase; n=5; Comamona... 59 1e-07
UniRef50_Q8XLQ0 Cluster: tRNA pseudouridine synthase A 1; n=4; C... 57 5e-07
UniRef50_Q5LNR0 Cluster: tRNA pseudouridine synthase A; n=45; Al... 55 1e-06
UniRef50_Q7M9U3 Cluster: tRNA pseudouridine synthase A; n=2; Wol... 55 2e-06
UniRef50_A5I338 Cluster: Pseudouridylate synthase; n=7; Clostrid... 54 2e-06
UniRef50_Q00Z96 Cluster: Pseudouridylate synthase; n=2; Ostreoco... 54 2e-06
UniRef50_Q890R5 Cluster: tRNA pseudouridine synthase A 2; n=11; ... 54 4e-06
UniRef50_Q6I3T8 Cluster: tRNA pseudouridine synthase A 2; n=12; ... 53 6e-06
UniRef50_Q3UAA3 Cluster: Pseudouridylate synthase; n=8; Eutheria... 53 7e-06
UniRef50_Q93NE2 Cluster: tRNA pseudouridine synthase A; n=5; Cys... 52 2e-05
UniRef50_A5ULI2 Cluster: Pseudouridylate synthase; n=1; Methanob... 51 2e-05
UniRef50_A7DDE8 Cluster: tRNA pseudouridine synthase A; n=3; Rhi... 50 5e-05
UniRef50_Q21IY8 Cluster: Pseudouridylate synthase; n=2; Gammapro... 49 9e-05
UniRef50_Q5NG36 Cluster: tRNA pseudouridine synthase A; n=11; Fr... 49 9e-05
UniRef50_Q1MM77 Cluster: Pseudouridylate synthase; n=13; Alphapr... 49 1e-04
UniRef50_A3XF14 Cluster: TRNA pseudouridine synthase; n=1; Roseo... 49 1e-04
UniRef50_Q72I65 Cluster: tRNA pseudouridine synthase A; n=3; The... 49 1e-04
UniRef50_Q820P8 Cluster: tRNA pseudouridine synthase A; n=10; Pr... 49 1e-04
UniRef50_Q95XD5 Cluster: Putative uncharacterized protein; n=2; ... 48 2e-04
UniRef50_Q17C60 Cluster: Pseudouridylate synthase; n=2; Culicida... 48 2e-04
UniRef50_Q7TU07 Cluster: tRNA pseudouridine synthase A; n=1; Pir... 48 2e-04
UniRef50_Q8R7Y7 Cluster: tRNA pseudouridine synthase A; n=9; Clo... 48 2e-04
UniRef50_A6Q408 Cluster: Pseudouridylate synthase; n=2; unclassi... 48 3e-04
UniRef50_A5WGT0 Cluster: Pseudouridylate synthase; n=4; Moraxell... 48 3e-04
UniRef50_Q88XU9 Cluster: tRNA pseudouridine synthase A; n=10; La... 48 3e-04
UniRef50_A3ZQX0 Cluster: Pseudouridylate synthase; n=2; Bacteria... 47 4e-04
UniRef50_A7SJV8 Cluster: Predicted protein; n=1; Nematostella ve... 47 5e-04
UniRef50_A2DE30 Cluster: tRNA pseudouridine synthase family prot... 47 5e-04
UniRef50_Q8ZXR6 Cluster: tRNA pseudouridine synthase A; n=4; Pyr... 47 5e-04
UniRef50_Q1N6P3 Cluster: Pseudouridylate synthase; n=2; Gammapro... 46 6e-04
UniRef50_Q6I4Q2 Cluster: tRNA pseudouridine synthase A 1; n=14; ... 46 6e-04
UniRef50_Q74L59 Cluster: tRNA pseudouridine synthase A; n=18; Ba... 46 9e-04
UniRef50_Q47HQ7 Cluster: Pseudouridylate synthase; n=1; Dechloro... 46 0.001
UniRef50_A5CET3 Cluster: Pseudouridylate synthase; n=1; Orientia... 45 0.001
UniRef50_A5PKS2 Cluster: LOC100101318 protein; n=4; Xenopus|Rep:... 45 0.002
UniRef50_UPI000049A0B0 Cluster: pseudouridine synthase; n=1; Ent... 44 0.003
UniRef50_Q0F2X2 Cluster: Pseudouridylate synthase; n=1; Mariprof... 44 0.003
UniRef50_A6TWE8 Cluster: Pseudouridylate synthase; n=4; Clostrid... 44 0.003
UniRef50_A4CLB7 Cluster: TRNA pseudouridine synthase A; n=1; Rob... 44 0.003
UniRef50_Q9KTA4 Cluster: tRNA pseudouridine synthase A; n=29; Ga... 44 0.003
UniRef50_O26928 Cluster: tRNA pseudouridine synthase A; n=1; Met... 44 0.003
UniRef50_P60350 Cluster: tRNA pseudouridine synthase A; n=6; Des... 44 0.003
UniRef50_Q8XXX8 Cluster: tRNA pseudouridine synthase A; n=50; Be... 44 0.005
UniRef50_Q5L3Q7 Cluster: tRNA pseudouridine synthase A; n=11; Ba... 44 0.005
UniRef50_A7F2S8 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_A2QE34 Cluster: Catalytic activity: tRNA uridine <=> tR... 43 0.006
UniRef50_Q1Q1P7 Cluster: Pseudouridylate synthase; n=1; Candidat... 43 0.008
UniRef50_A5D5F5 Cluster: Pseudouridylate synthase; n=2; Clostrid... 42 0.011
UniRef50_A4ARQ7 Cluster: Pseudouridylate synthase; n=2; Flavobac... 42 0.011
UniRef50_Q2NHB4 Cluster: Pseudouridylate synthase; n=1; Methanos... 42 0.011
UniRef50_Q9RS37 Cluster: tRNA pseudouridine synthase A; n=2; Dei... 42 0.011
UniRef50_Q1YHJ2 Cluster: Pseudouridylate synthase; n=2; Alphapro... 42 0.014
UniRef50_Q8DWH1 Cluster: tRNA pseudouridine synthase A; n=42; La... 42 0.014
UniRef50_Q5FPX3 Cluster: tRNA pseudouridine synthase A; n=4; Rho... 42 0.014
UniRef50_O28544 Cluster: tRNA pseudouridine synthase A; n=1; Arc... 42 0.014
UniRef50_A7AKE9 Cluster: Putative uncharacterized protein; n=2; ... 42 0.018
UniRef50_A2ZIV2 Cluster: Pseudouridylate synthase; n=2; Oryza sa... 42 0.018
UniRef50_Q8I0W4 Cluster: TRNA pseudouridine synthase, putative; ... 42 0.018
UniRef50_Q54RR6 Cluster: Pseudouridylate synthase; n=1; Dictyost... 42 0.018
UniRef50_Q8R601 Cluster: tRNA pseudouridine synthase A; n=3; Fus... 42 0.018
UniRef50_UPI00004993EF Cluster: tRNA pseudouridine synthase; n=1... 41 0.024
UniRef50_Q3Y386 Cluster: Pseudouridylate synthase; n=3; Firmicut... 41 0.024
UniRef50_A0B7V0 Cluster: Pseudouridylate synthase; n=1; Methanos... 41 0.024
UniRef50_A6C4N8 Cluster: Pseudouridylate synthase; n=1; Planctom... 41 0.032
UniRef50_Q011R7 Cluster: Exopolyphosphatases and related protein... 41 0.032
UniRef50_Q5KC13 Cluster: Pseudouridylate synthase, putative; n=2... 41 0.032
UniRef50_Q2LWJ8 Cluster: Pseudouridylate synthase; n=1; Syntroph... 40 0.043
UniRef50_A3JGC0 Cluster: Pseudouridylate synthase; n=4; Alteromo... 40 0.043
UniRef50_A1HQP5 Cluster: Pseudouridylate synthase; n=1; Thermosi... 40 0.043
UniRef50_Q22TA6 Cluster: Pseudouridylate synthase; n=1; Tetrahym... 40 0.043
UniRef50_Q7NAQ9 Cluster: tRNA pseudouridine synthase A; n=1; Myc... 40 0.043
UniRef50_Q4FNF9 Cluster: Pseudouridylate synthase; n=6; Bacteria... 40 0.056
UniRef50_A7CTY5 Cluster: tRNA pseudouridine synthase A; n=1; Opi... 40 0.056
UniRef50_A6FXP9 Cluster: Pseudouridylate synthase; n=1; Plesiocy... 40 0.056
UniRef50_A6DH96 Cluster: Pseudouridylate synthase; n=1; Lentisph... 40 0.056
UniRef50_Q00ST8 Cluster: TRNA pseudouridylate synthase; n=2; Ost... 40 0.056
UniRef50_Q4D3D3 Cluster: Putative uncharacterized protein; n=3; ... 40 0.056
UniRef50_Q8X025 Cluster: Related to pseudouridine synthase 3; n=... 40 0.056
UniRef50_O87016 Cluster: tRNA pseudouridine synthase A; n=132; P... 40 0.056
UniRef50_Q7U335 Cluster: tRNA pseudouridine synthase A; n=7; Gam... 40 0.056
UniRef50_Q6ANM1 Cluster: tRNA pseudouridine synthase A 1; n=1; D... 40 0.056
UniRef50_Q4SEJ2 Cluster: Pseudouridylate synthase; n=3; Tetraodo... 40 0.074
UniRef50_Q11XU3 Cluster: Pseudouridylate synthase; n=1; Cytophag... 40 0.074
UniRef50_A4CM73 Cluster: Pseudouridylate synthase; n=1; Robigini... 40 0.074
UniRef50_A1AXN3 Cluster: Pseudouridylate synthase; n=3; Bacteria... 40 0.074
UniRef50_Q9PP96 Cluster: tRNA pseudouridine synthase A; n=13; Ca... 40 0.074
UniRef50_Q89ZY4 Cluster: tRNA pseudouridine synthase A; n=3; Bac... 40 0.074
UniRef50_Q64XV0 Cluster: tRNA pseudouridine synthase A; n=16; Ba... 40 0.074
UniRef50_A7RII9 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 39 0.098
UniRef50_Q9X1R0 Cluster: tRNA pseudouridine synthase A; n=5; The... 39 0.098
UniRef50_Q72DL8 Cluster: tRNA pseudouridine synthase A; n=2; Des... 39 0.098
UniRef50_Q6MDE3 Cluster: tRNA pseudouridine synthase A 2; n=1; C... 39 0.098
UniRef50_Q59S63 Cluster: tRNA pseudouridine synthase 1; n=2; Sac... 39 0.098
UniRef50_A4EA88 Cluster: Pseudouridylate synthase; n=1; Collinse... 39 0.13
UniRef50_A5K9J6 Cluster: tRNA pseudouridine synthase, putative; ... 39 0.13
UniRef50_UPI0000DB7775 Cluster: PREDICTED: similar to CG3045-PA;... 38 0.17
UniRef50_Q4UA31 Cluster: TRNA-pseudouridine synthase I, putative... 38 0.17
UniRef50_A6R922 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17
UniRef50_Q8TU65 Cluster: tRNA pseudouridine synthase A; n=5; Arc... 38 0.17
UniRef50_Q8CXS6 Cluster: tRNA pseudouridine synthase A; n=3; Lep... 38 0.17
UniRef50_Q09524 Cluster: Probable tRNA pseudouridine synthase ta... 38 0.17
UniRef50_UPI00015BE519 Cluster: UPI00015BE519 related cluster; n... 38 0.23
UniRef50_Q1IRQ4 Cluster: Pseudouridylate synthase; n=2; Acidobac... 38 0.23
UniRef50_Q6NKP7 Cluster: Pseudouridylate synthase; n=8; Magnolio... 38 0.23
UniRef50_Q8I3U5 Cluster: Putative uncharacterized protein PFE081... 38 0.23
UniRef50_Q6C194 Cluster: Pseudouridylate synthase; n=1; Yarrowia... 38 0.23
UniRef50_A5E2I9 Cluster: Pseudouridylate synthase; n=4; Saccharo... 38 0.23
UniRef50_Q8D2P5 Cluster: tRNA pseudouridine synthase A; n=1; Wig... 38 0.23
UniRef50_A7C1F2 Cluster: tRNA pseudouridine synthase A; n=1; Beg... 38 0.30
UniRef50_A6NVS7 Cluster: Pseudouridylate synthase; n=1; Bacteroi... 38 0.30
UniRef50_Q9W282 Cluster: Pseudouridylate synthase; n=2; Sophopho... 38 0.30
UniRef50_O84469 Cluster: tRNA pseudouridine synthase A; n=7; Chl... 38 0.30
UniRef50_Q1NYR1 Cluster: TRNA pseudouridine synthase A; n=2; Can... 37 0.40
UniRef50_Q0U5E9 Cluster: Putative uncharacterized protein; n=1; ... 37 0.40
UniRef50_A2SU30 Cluster: Pseudouridylate synthase; n=1; Methanoc... 37 0.40
UniRef50_Q1FEL6 Cluster: Pseudouridylate synthase; n=1; Clostrid... 37 0.53
UniRef50_A7ANC8 Cluster: Putative uncharacterized protein; n=1; ... 37 0.53
UniRef50_P47428 Cluster: tRNA pseudouridine synthase A; n=3; Myc... 37 0.53
UniRef50_Q9BZE2 Cluster: tRNA pseudouridine synthase 3; n=19; Eu... 37 0.53
UniRef50_Q6CC39 Cluster: tRNA pseudouridine synthase 1; n=1; Yar... 37 0.53
UniRef50_Q2S4S9 Cluster: Pseudouridylate synthase; n=1; Saliniba... 36 0.69
UniRef50_A2E6F9 Cluster: tRNA pseudouridine synthase family prot... 36 0.69
UniRef50_A4R2D6 Cluster: Putative uncharacterized protein; n=1; ... 36 0.69
UniRef50_Q6MEE7 Cluster: tRNA pseudouridine synthase A 1; n=1; C... 36 0.69
UniRef50_A4XKB7 Cluster: Pseudouridylate synthase; n=3; Clostrid... 36 0.92
UniRef50_Q4WYK4 Cluster: Pseudouridylate synthase 3; n=6; Euroti... 36 0.92
UniRef50_Q6AD25 Cluster: tRNA pseudouridine synthase A; n=4; Act... 36 0.92
UniRef50_Q5PAN6 Cluster: tRNA pseudouridine synthase A; n=12; Al... 36 0.92
UniRef50_A5USG0 Cluster: Pseudouridylate synthase; n=3; Chlorofl... 36 1.2
UniRef50_Q75M65 Cluster: Pseudouridylate synthase; n=2; Oryza sa... 36 1.2
UniRef50_Q4P5K5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_Q4P397 Cluster: Putative uncharacterized protein; n=1; ... 36 1.2
UniRef50_UPI0000D554D8 Cluster: PREDICTED: similar to CG4159-PA;... 35 1.6
UniRef50_Q47LM3 Cluster: Pseudouridylate synthase; n=2; Actinomy... 35 1.6
UniRef50_Q00RV7 Cluster: TRUA1_PARUW tRNA pseudouridine synthase... 35 1.6
UniRef50_Q5CPW7 Cluster: Pus1p-like type II pseudousynthas TruA;... 35 1.6
UniRef50_Q54TQ3 Cluster: Putative uncharacterized protein; n=1; ... 35 1.6
UniRef50_Q22BB0 Cluster: TRNA pseudouridine synthase family prot... 35 1.6
UniRef50_A6TQL8 Cluster: Pseudouridylate synthase; n=1; Alkaliph... 35 2.1
UniRef50_Q6BV13 Cluster: Similar to CA2663|CaNUP133 Candida albi... 35 2.1
UniRef50_UPI00015B411C Cluster: PREDICTED: similar to pseudourid... 34 2.8
UniRef50_UPI0000E87E98 Cluster: tRNA pseudouridine synthase A; n... 34 2.8
UniRef50_UPI00006CC0EE Cluster: tRNA pseudouridine synthase fami... 34 2.8
UniRef50_UPI000018F668 Cluster: similar to DNA helicase; n=1; Rh... 34 2.8
UniRef50_Q0LPW8 Cluster: Pseudouridylate synthase; n=1; Herpetos... 34 2.8
UniRef50_A0Z5L5 Cluster: TRNA pseudouridine synthase A; n=1; mar... 34 2.8
UniRef50_Q4Q3H7 Cluster: Putative uncharacterized protein; n=3; ... 34 2.8
UniRef50_A1C4K8 Cluster: FAD binding domain protein; n=1; Asperg... 34 2.8
UniRef50_UPI00015B40A8 Cluster: PREDICTED: similar to pseudourid... 34 3.7
UniRef50_UPI0000DAE4B2 Cluster: hypothetical protein Rgryl_01000... 34 3.7
UniRef50_Q8GB97 Cluster: Pseudouridylate synthase; n=2; Clostrid... 34 3.7
UniRef50_A7HCM5 Cluster: tRNA-pseudouridine synthase I; n=2; Ana... 34 3.7
UniRef50_A7ASP1 Cluster: tRNA pseudouridine synthase, putative; ... 34 3.7
UniRef50_Q73KE3 Cluster: tRNA pseudouridine synthase A; n=1; Tre... 34 3.7
UniRef50_O94295 Cluster: tRNA pseudouridine synthase 2; n=1; Sch... 34 3.7
UniRef50_Q30RV9 Cluster: Pseudouridylate synthase; n=1; Thiomicr... 33 4.9
UniRef50_Q1FHP1 Cluster: Extracellular solute-binding protein, f... 33 4.9
UniRef50_A3I2E1 Cluster: TRNA pseudouridine synthase A; n=1; Alg... 33 4.9
UniRef50_A0LIV1 Cluster: Pseudouridylate synthase; n=1; Syntroph... 33 4.9
UniRef50_A0DFY8 Cluster: Pseudouridylate synthase; n=1; Parameci... 33 4.9
UniRef50_A3GG38 Cluster: Nuclear pore complex protein involved i... 33 4.9
UniRef50_Q979R4 Cluster: tRNA pseudouridine synthase A; n=1; The... 33 4.9
UniRef50_Q9ZCA3 Cluster: tRNA pseudouridine synthase A; n=13; Ri... 33 4.9
UniRef50_UPI00006CB5F6 Cluster: hypothetical protein TTHERM_0053... 33 6.5
UniRef50_A1AY01 Cluster: Putative uncharacterized protein precur... 33 6.5
UniRef50_Q9C5K6 Cluster: Pseudouridylate synthase; n=3; core eud... 33 6.5
UniRef50_A6SH63 Cluster: Predicted protein; n=1; Botryotinia fuc... 33 6.5
UniRef50_A2TUS1 Cluster: Pseudouridylate synthase; n=2; Flavobac... 33 8.6
UniRef50_Q23DF3 Cluster: Putative uncharacterized protein; n=1; ... 33 8.6
UniRef50_A6QYD4 Cluster: Predicted protein; n=2; Ajellomyces cap... 33 8.6
UniRef50_A3LX03 Cluster: Pseudouridylate synthase; n=4; Saccharo... 33 8.6
UniRef50_P60349 Cluster: tRNA pseudouridine synthase A; n=13; Ac... 33 8.6
UniRef50_Q8SQI1 Cluster: Probable DNA-3-methyladenine glycosylas... 33 8.6
>UniRef50_UPI0000D571F8 Cluster: PREDICTED: similar to CG7042-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG7042-PA - Tribolium castaneum
Length = 484
Score = 114 bits (275), Expect = 2e-24
Identities = 63/171 (36%), Positives = 98/171 (57%), Gaps = 8/171 (4%)
Query: 56 RLAVLKKDVVIPENVSIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKK 115
R+A+ K V E+ +I N++P+EE++RC F F+I++ KE AK EG HDF TF
Sbjct: 131 RIAIAKTGVT--EHATILNLLPIEEYQRCLFFYCDSFNIDEMKEAAKVFEGLHDFRTFMG 188
Query: 116 FDKLLQHKHNRRELKSVTIRAGKPVVTAHTE----SRGSA--FDYWDIEFHGRAFVHNQI 169
K RR + V + G+ + + + GSA + ++DI F++ Q+
Sbjct: 189 RGSHDPDKITRRVVTRVDVCDGRALTYSSFSWPRFASGSAENYQFYDIYVQATGFLYRQV 248
Query: 170 RRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
RRMV +LI+V GK ++K+ML++PS SW I+ P+ GLYLCEV++
Sbjct: 249 RRMVASLIAVGQGKKTRRELKLMLEVPSHRSWDERIKTVPAYGLYLCEVDF 299
Score = 32.7 bits (71), Expect = 8.6
Identities = 15/29 (51%), Positives = 20/29 (68%)
Query: 28 DPESVQGMMELSLLKLRSLNYPNVTLSSR 56
DP +VQG +E++L +L N P V LSSR
Sbjct: 33 DPSTVQGQLEMALKRLNPTNDPVVYLSSR 61
>UniRef50_Q29EU3 Cluster: GA20054-PA; n=2; Diptera|Rep: GA20054-PA -
Drosophila pseudoobscura (Fruit fly)
Length = 531
Score = 108 bits (260), Expect = 1e-22
Identities = 57/158 (36%), Positives = 87/158 (55%), Gaps = 13/158 (8%)
Query: 76 IPVEEWKRCHFI-------RLAEFDIEKFKEGAKHLEGYHDFSTFKKFD--KLLQHKH-- 124
+PVEE RC+F+ + FDIE+ + A+ G HDF TF K L H
Sbjct: 164 VPVEEIDRCYFLLYSVLPAQAPTFDIERIRNAARMFIGVHDFRTFMSVSRQKSLSRDHPM 223
Query: 125 -NRRELKSVTIRAGKPV-VTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIG 182
R++ + IR G+ + + ++ +DYWDIE ++F++ Q+RR+VG+L+S+
Sbjct: 224 FTLRKIDEINIRPGRTLALPSNATLAAETYDYWDIEIKAKSFLYKQVRRIVGSLLSLGSD 283
Query: 183 KLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
++ + ML IPSKHSW S + P+ GLYLC V Y
Sbjct: 284 RIDEKCIYQMLTIPSKHSWDSRVVPAPACGLYLCRVHY 321
>UniRef50_Q7Q194 Cluster: ENSANGP00000013201; n=2; Culicidae|Rep:
ENSANGP00000013201 - Anopheles gambiae str. PEST
Length = 490
Score = 106 bits (254), Expect = 6e-22
Identities = 56/156 (35%), Positives = 86/156 (55%), Gaps = 8/156 (5%)
Query: 56 RLAVLKKDVVIP---ENVSIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFST 112
RLAVLK++ + A IP+EE RC+F+ +EFDI F A+ EG HDF T
Sbjct: 129 RLAVLKREYARESGRQQHPHARFIPIEEHDRCYFLGHSEFDINAFASVARMFEGMHDFRT 188
Query: 113 F----KKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF-DYWDIEFHGRAFVHN 167
F K + + H+ R + +T+ G + A R + D+WD+ GR+F++
Sbjct: 189 FMAVAKGNPRQQEAMHSLRRIDQITVERGHTMTAAFNRERTEHYYDFWDVRIRGRSFLYR 248
Query: 168 QIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHS 203
Q+RRMVG ++ A G++ D+ ML +PS++SW S
Sbjct: 249 QVRRMVGAWVAAAEGRITERDIYRMLTVPSQNSWCS 284
Score = 36.7 bits (81), Expect = 0.53
Identities = 17/29 (58%), Positives = 23/29 (79%)
Query: 28 DPESVQGMMELSLLKLRSLNYPNVTLSSR 56
DP +VQG++E +LLKLR +N P + LSSR
Sbjct: 31 DPHTVQGVIEEALLKLRPVNEPLLKLSSR 59
>UniRef50_UPI0000DB6E84 Cluster: PREDICTED: similar to CG7042-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG7042-PA
- Apis mellifera
Length = 484
Score = 105 bits (252), Expect = 1e-21
Identities = 59/152 (38%), Positives = 86/152 (56%), Gaps = 6/152 (3%)
Query: 76 IPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHK--HNRRELKSVT 133
IP+ E RC IR FD+E+ K + G DF TF K++ +K + R L S+T
Sbjct: 126 IPITEINRCFHIRSDTFDLERIKRATQLFIGTKDFRTFSA--KIVGNKPINYVRNLNSLT 183
Query: 134 IRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVML 193
I G P++ S+ F+YW+I R F++ Q+RR+VG L ++ GK+ D+ VML
Sbjct: 184 IEKGYPLMPNDPLSQN--FEYWNIICSSRGFLYKQVRRIVGALFALGSGKITEKDITVML 241
Query: 194 QIPSKHSWHSFIQNCPSDGLYLCEVEYDPKDL 225
Q+P H++ S I+ P+ GLYL VEY K L
Sbjct: 242 QVPGCHNYLSQIETAPAYGLYLMNVEYCHKQL 273
>UniRef50_UPI00015B44A3 Cluster: PREDICTED: similar to CG34140-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG34140-PA - Nasonia vitripennis
Length = 298
Score = 102 bits (244), Expect = 9e-21
Identities = 56/164 (34%), Positives = 97/164 (59%), Gaps = 9/164 (5%)
Query: 64 VVIPENVSIANVIPVEEWKRCHFIRL--AEFDIEKFKEGAKHLEGYHDFSTF--KKFDKL 119
++IP++ + + P+ E R F+ + FDIE+ + G K G DF TF +K D+
Sbjct: 129 LIIPKD-PLDHRFPIAEANRSLFLNMYPQNFDIERLRSGIKLFCGTKDFMTFSARKRDRN 187
Query: 120 LQHKHNRRELKS--VTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLI 177
+ + R +++ VT++ P+++ S+ DYW +EF R+F++NQIRR+VG+LI
Sbjct: 188 PEFEMRRNFVRTLHVTMKEAGPLMSFDPLSKN--LDYWHLEFTSRSFLYNQIRRIVGSLI 245
Query: 178 SVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYD 221
++ K+ +D++ M+Q+PS H+W+ + GLYL VEYD
Sbjct: 246 ALGSHKVSEEDIQTMIQVPSHHNWNPHVTPAAPRGLYLKNVEYD 289
>UniRef50_Q6GQ53 Cluster: Pseudouridylate synthase; n=4;
Euteleostomi|Rep: Pseudouridylate synthase - Xenopus
laevis (African clawed frog)
Length = 298
Score = 79.4 bits (187), Expect = 8e-14
Identities = 48/151 (31%), Positives = 77/151 (50%), Gaps = 6/151 (3%)
Query: 76 IPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIR 135
+PV E C I+ ++ E +K L G H+FS F+ + K + L+ I
Sbjct: 137 LPVFEGNLCWAIQDG-LNVTAINEASKMLLGTHNFSAFRSANSENAFKSPIKTLQQADIN 195
Query: 136 AGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
++T H +SR F WD F R+F++ Q+RRM G L++V G+L P +K L+
Sbjct: 196 PSCGILTHHWQSRNLQF--WDFTFRARSFLYKQVRRMTGALVAVGQGRLTPQQIKEFLEN 253
Query: 196 PSKHSW-HSFIQNCPSDGLYLCEVEYDPKDL 225
+ + +F+ P GL+L +VEYD +L
Sbjct: 254 QDPNCFLGNFV--APPHGLFLKDVEYDGTEL 282
>UniRef50_Q8N0Z8 Cluster: tRNA pseudouridine synthase-like 1; n=11;
Eutheria|Rep: tRNA pseudouridine synthase-like 1 - Homo
sapiens (Human)
Length = 303
Score = 74.1 bits (174), Expect = 3e-12
Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 4/145 (2%)
Query: 76 IPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIR 135
+PV E C + D+ +E A+HL G HDFS F+ + SV+
Sbjct: 144 LPVFERNLCWTLPADCLDMVAMQEAAQHLLGTHDFSAFQSAGSPVPSPVRTLRRVSVSPG 203
Query: 136 AGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
P+VT ESR F W++EF ++F++ Q+RRM L++V +G L P VK +L+
Sbjct: 204 QASPLVTPE-ESRKLRF--WNLEFESQSFLYRQVRRMTAVLVAVGLGALAPAQVKTILES 260
Query: 196 PSKHSWHSFIQNCPSDGLYLCEVEY 220
H + P+ GL+L V Y
Sbjct: 261 QDPLGKHQ-TRVAPAHGLFLKSVLY 284
>UniRef50_Q4SXZ4 Cluster: Chromosome undetermined SCAF12265, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF12265, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 181
Score = 71.7 bits (168), Expect = 2e-11
Identities = 42/145 (28%), Positives = 72/145 (49%), Gaps = 4/145 (2%)
Query: 76 IPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIR 135
+P+ E C +R E D+ E A L G HDFS+F+ + L K+ + L + TI+
Sbjct: 36 VPLPEHGFCWNLRDTELDVGGMCEAAALLVGVHDFSSFRAVNSDLPFKNPVKRLDAATIQ 95
Query: 136 AGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
G H + ++ F R+F++ Q+RRM G L++V G+L +K +L+
Sbjct: 96 TGVSFAQVHYH---RVIPFLELIFTSRSFLYKQVRRMTGALVAVGQGRLSVAQLKEVLEA 152
Query: 196 PSKHSWHSFIQNCPSDGLYLCEVEY 220
++ + P+ GL+L V+Y
Sbjct: 153 RDSLAYPQGL-TAPAHGLFLTRVDY 176
>UniRef50_UPI0000E482DE Cluster: PREDICTED: similar to MGC80334
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to MGC80334 protein -
Strongylocentrotus purpuratus
Length = 306
Score = 69.3 bits (162), Expect = 8e-11
Identities = 35/128 (27%), Positives = 63/128 (49%), Gaps = 2/128 (1%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
DI KE + G HDF+ F+ K + + + R + + H ++ +
Sbjct: 157 DIPSMKEASGRFVGTHDFTAFRNSSMDDDKKSPIKTIDMIEFRRTRGFLYHHC-NKMAQL 215
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
++ ++ FH R+F++ QIRRM G L++V +G++ P + +L+ H P+ G
Sbjct: 216 EFLELTFHSRSFLYKQIRRMTGALVAVGLGRIAPSHITTILESRDNSHMHRTTM-APAHG 274
Query: 213 LYLCEVEY 220
LYL E+ Y
Sbjct: 275 LYLKEISY 282
>UniRef50_Q1FLK6 Cluster: Pseudouridylate synthase; n=1; Clostridium
phytofermentans ISDg|Rep: Pseudouridylate synthase -
Clostridium phytofermentans ISDg
Length = 276
Score = 59.3 bits (137), Expect = 9e-08
Identities = 47/151 (31%), Positives = 70/151 (46%), Gaps = 20/151 (13%)
Query: 70 VSIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRREL 129
+SI V V E ++ ++ DI K KE AK+L G HDF F D K RE+
Sbjct: 145 ISIGEVPSVFE-RKYNYYCFKRPDIAKMKEAAKYLVGKHDFKAFS--DNKRMKKSTEREI 201
Query: 130 KSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDV 189
S+ I + + I HG F + +R MVGTL+ V + K++P D+
Sbjct: 202 YSLEIYGDEKEIV--------------ITVHGDDFWPHMVRIMVGTLLDVGLSKIEPMDI 247
Query: 190 KVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
K +L+ + I+ + GL+L EV Y
Sbjct: 248 KRILESKDRDKAGETIE---AKGLFLTEVHY 275
>UniRef50_Q28LN3 Cluster: Pseudouridylate synthase; n=15;
Alphaproteobacteria|Rep: Pseudouridylate synthase -
Jannaschia sp. (strain CCS1)
Length = 261
Score = 58.8 bits (136), Expect = 1e-07
Identities = 45/137 (32%), Positives = 67/137 (48%), Gaps = 18/137 (13%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSV-TIRAGKPVVTAHTESRGSA 151
D+ EGA+HL G HDF+TF+ H +K++ IR + + A TE R
Sbjct: 137 DVTAMAEGARHLIGKHDFTTFR-----ATHCQALSPIKTMDEIRVEEVSLPAGTEIR--- 188
Query: 152 FDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSD 211
++F+HNQ+R +VG+L V G PDD++ L+ + + P D
Sbjct: 189 -----FHLKAQSFLHNQVRSIVGSLEHVGSGAWAPDDMRRALEACDRAECGTV---APPD 240
Query: 212 GLYLCEVEYDPKDLFYD 228
GLY+ V YD +D F D
Sbjct: 241 GLYMTGVGYD-EDPFAD 256
>UniRef50_A1WAT5 Cluster: Pseudouridylate synthase; n=5;
Comamonadaceae|Rep: Pseudouridylate synthase -
Acidovorax sp. (strain JS42)
Length = 274
Score = 58.8 bits (136), Expect = 1e-07
Identities = 30/106 (28%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D + + +HL G HDF++F+ Q K + L + I P T + G
Sbjct: 135 DEQAMHKAVQHLLGEHDFTSFRA--SACQAKSPVKTLHRIDITRRAPPAGESTGTHGCVP 192
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSK 198
YW EF G AF+H+ IR ++G ++++ G P+ ++ +L+ S+
Sbjct: 193 CYWRFEFEGNAFLHHMIRNIMGCIVAIGQGLYPPEWMRTVLEARSR 238
>UniRef50_Q8XLQ0 Cluster: tRNA pseudouridine synthase A 1; n=4;
Clostridium|Rep: tRNA pseudouridine synthase A 1 -
Clostridium perfringens
Length = 248
Score = 56.8 bits (131), Expect = 5e-07
Identities = 36/130 (27%), Positives = 63/130 (48%), Gaps = 19/130 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
+ D+E +EGAK+L G HDF +F ++K R + S+ +++
Sbjct: 138 KLDLEAMEEGAKYLLGTHDFKSFTSLKS--KNKSTLRTINSIEFHENNNILS-------- 187
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
I+ +G F+ N +R MVGTL+ V +GK++P + +L+ + + P+
Sbjct: 188 ------IKINGNGFLLNMVRIMVGTLVDVGLGKIEPKYINDILEAKER---AKASEKAPA 238
Query: 211 DGLYLCEVEY 220
GL L E+ Y
Sbjct: 239 HGLCLLELNY 248
>UniRef50_Q5LNR0 Cluster: tRNA pseudouridine synthase A; n=45;
Alphaproteobacteria|Rep: tRNA pseudouridine synthase A -
Silicibacter pomeroyi
Length = 262
Score = 55.2 bits (127), Expect = 1e-06
Identities = 41/113 (36%), Positives = 57/113 (50%), Gaps = 10/113 (8%)
Query: 119 LLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYW---DIEFHGRA--FVHNQIRRMV 173
LL +H+ +S +A PV T E R A + + +I FH RA F+HNQ+R V
Sbjct: 147 LLLGRHDFTTFRSSICQAASPVKTLD-ELRVEAVESFSGPEIRFHVRARSFLHNQVRSFV 205
Query: 174 GTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYDPKDLF 226
GTL V G P+DV+ L+ + + CP GLYL V Y P+ +F
Sbjct: 206 GTLERVGAGAWAPEDVRSALEARDRAACGPV---CPPQGLYLARVGY-PEPVF 254
>UniRef50_Q7M9U3 Cluster: tRNA pseudouridine synthase A; n=2;
Wolinella succinogenes|Rep: tRNA pseudouridine synthase
A - Wolinella succinogenes
Length = 253
Score = 54.8 bits (126), Expect = 2e-06
Identities = 38/129 (29%), Positives = 58/129 (44%), Gaps = 20/129 (15%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D K +E K L G+HDF+ FKK Q K RE++ + +
Sbjct: 134 DERKIQEAMKLLVGWHDFALFKKSGS--QEKSTLREMRRCWLYRYR-------------- 177
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
YW F F+ QIR +VG L+ V G++ ++ K L+ + F + P G
Sbjct: 178 SYWVFYFEANGFLRLQIRLLVGALLKVGRGEMSLEEFKEQLEAKRRF----FCEGAPPYG 233
Query: 213 LYLCEVEYD 221
LYLC+V ++
Sbjct: 234 LYLCKVSFE 242
>UniRef50_A5I338 Cluster: Pseudouridylate synthase; n=7;
Clostridiaceae|Rep: Pseudouridylate synthase -
Clostridium botulinum A str. ATCC 3502
Length = 246
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/129 (30%), Positives = 58/129 (44%), Gaps = 19/129 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
DIE KE +L G HDF++F R K T+R + +S
Sbjct: 137 DIEAMKEACTYLVGRHDFASFTA----------ARSKKKSTVRTLYSIDIIKKDS----- 181
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
Y DI + G F+H IR + GTLI + + L+ DVK++L + PS G
Sbjct: 182 -YVDIVYLGSGFLHKMIRILTGTLIEIGLHNLKSVDVKIILDAEDRRKAG---PTAPSQG 237
Query: 213 LYLCEVEYD 221
L++ V+Y+
Sbjct: 238 LFMTSVDYE 246
>UniRef50_Q00Z96 Cluster: Pseudouridylate synthase; n=2;
Ostreococcus|Rep: Pseudouridylate synthase -
Ostreococcus tauri
Length = 338
Score = 54.4 bits (125), Expect = 2e-06
Identities = 39/130 (30%), Positives = 63/130 (48%), Gaps = 7/130 (5%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D++ + A L G HDFS+F+ Q K R + S+ + + E+RG+
Sbjct: 191 DVDAMRRAASVLIGKHDFSSFRASG--CQAKSPIRTITSLDV-VSRTTEWPSPEARGTRQ 247
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ + +F+++Q+R +VG L SV G L DDV+ +L+ Q P+ G
Sbjct: 248 EV-SVRVEAPSFLYHQVRLLVGALKSVGAGDLTVDDVRELLEAKDV---SQAPQMAPAHG 303
Query: 213 LYLCEVEYDP 222
LYL +V Y P
Sbjct: 304 LYLMDVGYLP 313
>UniRef50_Q890R5 Cluster: tRNA pseudouridine synthase A 2; n=11;
Clostridium|Rep: tRNA pseudouridine synthase A 2 -
Clostridium tetani
Length = 248
Score = 53.6 bits (123), Expect = 4e-06
Identities = 41/131 (31%), Positives = 63/131 (48%), Gaps = 19/131 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
E DI E +K L G HDF+ FKK L K R + ++ I +V H
Sbjct: 137 ELDINSMIEASKFLIGTHDFNAFKKSGGNL--KTTVRTITNINILKSNDIVEIHVS---- 190
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
G F++N +R + GTLI V + + +P+D+ ++LQ SK + + P+
Sbjct: 191 ----------GDGFLYNMVRIISGTLIEVGLSRRKPEDISIILQ--SKDRCKAGM-CAPA 237
Query: 211 DGLYLCEVEYD 221
GLYL E+ Y+
Sbjct: 238 RGLYLKELFYN 248
>UniRef50_Q6I3T8 Cluster: tRNA pseudouridine synthase A 2; n=12;
Bacillus|Rep: tRNA pseudouridine synthase A 2 - Bacillus
anthracis
Length = 245
Score = 53.2 bits (122), Expect = 6e-06
Identities = 37/130 (28%), Positives = 63/130 (48%), Gaps = 19/130 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
+ +++ KE AKHL G HDF+ F + K RE+ S+ + E G
Sbjct: 135 KLNVKSMKEAAKHLVGSHDFTAFSNAKS--KKKSMVREVYSLEVM----------EEAG- 181
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
+ I G F+HN +R++VG LI V +G+L + + +L+ ++ + + +
Sbjct: 182 ---FVQIRVSGNGFLHNMVRKIVGALIEVGLGQLAAEAIPQILEAKQRNQINCLAE---A 235
Query: 211 DGLYLCEVEY 220
GLYL VE+
Sbjct: 236 SGLYLENVEF 245
>UniRef50_Q3UAA3 Cluster: Pseudouridylate synthase; n=8;
Eutheria|Rep: Pseudouridylate synthase - Mus musculus
(Mouse)
Length = 280
Score = 52.8 bits (121), Expect = 7e-06
Identities = 45/172 (26%), Positives = 73/172 (42%), Gaps = 28/172 (16%)
Query: 74 NVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVT 133
N +PV E C ++ D+ +E A+HL G HDFS F+ + + R L+ V+
Sbjct: 107 NQLPVFEQNVCWALQTEYLDMAAMQEAAQHLLGTHDFSAFQSAGSPV--TNTVRTLRRVS 164
Query: 134 IRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHN------------------------QI 169
+ G P +W +EF ++F++ Q+
Sbjct: 165 VSPG-PASPFVLPEGSRRLQFWTLEFESQSFLYRQVGCLNPHRMGSGRHTCDNLSSLLQV 223
Query: 170 RRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYD 221
RRM L++V +G L P VKV+L+ + + P+ GL+L V YD
Sbjct: 224 RRMTAVLVAVGLGILAPTQVKVILESQDPLGKYQ-ARVAPARGLFLKSVLYD 274
>UniRef50_Q93NE2 Cluster: tRNA pseudouridine synthase A; n=5;
Cystobacterineae|Rep: tRNA pseudouridine synthase A -
Myxococcus xanthus
Length = 265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 18/152 (11%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
H+ A D+E ++ A HL G HDFS F+ D Q KH RE++S+ +
Sbjct: 128 HWEVFAPLDVEAMRQAAAHLLGRHDFSAFRAAD--CQAKHAVREIRSLAV---------- 175
Query: 145 TESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSF 204
G++ D G AF+ + +R + GTL+ V G+ V +L +
Sbjct: 176 ---EGTSGDAVSFVVEGTAFLKHMVRNLAGTLVEVGKGRRPASWVAEVLASQERKRAG-- 230
Query: 205 IQNCPSDGLYLCEVEYDPKDLFYDPDTTVESE 236
P GL L EV Y P T ++E
Sbjct: 231 -PTAPPQGLVLEEVFYRDGPPARTPGGTTDAE 261
>UniRef50_A5ULI2 Cluster: Pseudouridylate synthase; n=1;
Methanobrevibacter smithii ATCC 35061|Rep:
Pseudouridylate synthase - Methanobrevibacter smithii
(strain PS / ATCC 35061 / DSM 861)
Length = 290
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/142 (25%), Positives = 70/142 (49%), Gaps = 9/142 (6%)
Query: 90 AEFDIEKFKEGAKHLEGYHDFSTF-KKFDKLLQHKHNRRELKSVTIRA--GKPVVTAHTE 146
++ D+ K E A+ +G H+F+ F K+F K + ++ + K H +
Sbjct: 116 SDLDLYKLNEVAEIFKGTHNFTNFTKRFQKTTTRTIDDIKITKANLNDYHKKEFPNLH-D 174
Query: 147 SRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQ 206
+ F ++ +G +F+ N +R+M+ + VAIGKL + V+ +L P+++ + I+
Sbjct: 175 TLSPVF----VDIYGESFLWNMVRKMMRVFVDVAIGKLSLEKVEELLN-PAENDPRANIK 229
Query: 207 NCPSDGLYLCEVEYDPKDLFYD 228
D L L +++YD YD
Sbjct: 230 VLDPDYLILMDIKYDGVKFVYD 251
>UniRef50_A7DDE8 Cluster: tRNA pseudouridine synthase A; n=3;
Rhizobiales|Rep: tRNA pseudouridine synthase A -
Methylobacterium extorquens PA1
Length = 300
Score = 50.0 bits (114), Expect = 5e-05
Identities = 39/128 (30%), Positives = 57/128 (44%), Gaps = 15/128 (11%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D E A+ L G+HDFS F+ + Q K R L+ + + T R F
Sbjct: 187 DAELMHRAAQRLLGHHDFSAFRAAE--CQAKSPMRTLEQLDV----------TRVRMGLF 234
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ I R+F+H+Q+R M GTL+ +L DDV +L +KH P+ G
Sbjct: 235 EEIVIATSARSFLHHQVRAMAGTLMLAGCKRLSADDVAEILATGAKHRCGPL---APACG 291
Query: 213 LYLCEVEY 220
L V+Y
Sbjct: 292 LTFVGVDY 299
>UniRef50_Q21IY8 Cluster: Pseudouridylate synthase; n=2;
Gammaproteobacteria|Rep: Pseudouridylate synthase -
Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM
17024)
Length = 289
Score = 49.2 bits (112), Expect = 9e-05
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 3/112 (2%)
Query: 109 DFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQ 168
D ++ LL +H+ ++V +A PV T ++ ++ AF+H+
Sbjct: 163 DVPAMQEAASLLLGEHDFTSFRTVHCQAASPVRTMEVADVVQMGEFIVVQVTANAFLHHM 222
Query: 169 IRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
+R +VG L+ V G+L+P V ++++ + + P+ GLY V+Y
Sbjct: 223 VRNIVGVLLRVGRGELKPSRVTELIELRDR---SQAAETAPAAGLYFVNVQY 271
>UniRef50_Q5NG36 Cluster: tRNA pseudouridine synthase A; n=11;
Francisella tularensis|Rep: tRNA pseudouridine synthase
A - Francisella tularensis subsp. tularensis
Length = 258
Score = 49.2 bits (112), Expect = 9e-05
Identities = 37/130 (28%), Positives = 61/130 (46%), Gaps = 19/130 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
E DI+K + ++L G DFS+F+ + + R K+ I+ G +V
Sbjct: 134 ELDIDKMNQACEYLLGEQDFSSFRS-SQCQSNTPFRNIQKAEFIKQGSFIV--------- 183
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
E G AF+H+ IR +VG+L+ V +G P+ +KV+L+ + + +
Sbjct: 184 ------FEVVGNAFLHHMIRNLVGSLLKVGLGFESPEWIKVVLEAKDR---TQAAETAKA 234
Query: 211 DGLYLCEVEY 220
GLY VEY
Sbjct: 235 HGLYFVGVEY 244
>UniRef50_Q1MM77 Cluster: Pseudouridylate synthase; n=13;
Alphaproteobacteria|Rep: Pseudouridylate synthase -
Rhizobium leguminosarum bv. viciae (strain 3841)
Length = 272
Score = 48.8 bits (111), Expect = 1e-04
Identities = 39/128 (30%), Positives = 54/128 (42%), Gaps = 19/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D E A+ L G HDFSTF+ + +A PV T
Sbjct: 139 DHEVMHAAAQRLVGRHDFSTFR----------------AAHCQANSPVRTLDRLDVTRRG 182
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ +I ++F+HNQIR GTL GK PDDV+ L+ + + P DG
Sbjct: 183 ELIEIRATAQSFLHNQIRSFAGTLKLAGEGKWTPDDVEAALKARDRKACGPV---APPDG 239
Query: 213 LYLCEVEY 220
LY +V+Y
Sbjct: 240 LYFMQVDY 247
>UniRef50_A3XF14 Cluster: TRNA pseudouridine synthase; n=1;
Roseobacter sp. MED193|Rep: TRNA pseudouridine synthase
- Roseobacter sp. MED193
Length = 113
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 13/112 (11%)
Query: 84 CHFIRLA-EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVT 142
CH +R+ E + + GA+HL G + F+TF+ ++ Q K + L ++ I
Sbjct: 2 CHVLRVPPELYVAAMRNGARHLLGKYYFTTFRS--RICQAKSPVKALDALEIE------- 52
Query: 143 AHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQ 194
E G A R+ ++NQ+R +VGTL V G P+DVK L+
Sbjct: 53 ---EVEGLAGPELRFHLSARSLLYNQVRSIVGTLERVGAGSWTPEDVKTALE 101
>UniRef50_Q72I65 Cluster: tRNA pseudouridine synthase A; n=3;
Thermus thermophilus|Rep: tRNA pseudouridine synthase A
- Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM
7039)
Length = 253
Score = 48.8 bits (111), Expect = 1e-04
Identities = 38/133 (28%), Positives = 60/133 (45%), Gaps = 17/133 (12%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+E +E L G H+F F K + + REL ++ + A E R
Sbjct: 136 DLEAMEEALSLLLGRHNFLGFAKEET----RPGERELLEARLQVAEG--EAGLEVR---- 185
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ F G++F+ Q+R MVGTL+ V +GK P+ +K +L+ + P+ G
Sbjct: 186 ----LYFRGKSFLRGQVRGMVGTLLEVGLGKRPPESLKAILKTADRRLAG---PTAPAHG 238
Query: 213 LYLCEVEYDPKDL 225
LY E Y + L
Sbjct: 239 LYFVEAAYPEEKL 251
>UniRef50_Q820P8 Cluster: tRNA pseudouridine synthase A; n=10;
Proteobacteria|Rep: tRNA pseudouridine synthase A -
Nitrosomonas europaea
Length = 272
Score = 48.8 bits (111), Expect = 1e-04
Identities = 38/131 (29%), Positives = 62/131 (47%), Gaps = 19/131 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+EK + AK L G HDFS F+ + Q + R+L + I + H +
Sbjct: 146 DLEKMQMAAKLLIGKHDFSAFRSSE--CQSRTAIRQLTRLNI-------SQHQQ------ 190
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ EF AF+H+ +R ++G L+ + GK P+ ++++L+ K DG
Sbjct: 191 -LFVFEFCANAFLHHMVRNILGGLVYIGRGKYPPEWMRILLE---KRDRTLAAPTFSPDG 246
Query: 213 LYLCEVEYDPK 223
LYL V YD +
Sbjct: 247 LYLSGVRYDAR 257
>UniRef50_Q95XD5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 322
Score = 48.4 bits (110), Expect = 2e-04
Identities = 24/80 (30%), Positives = 47/80 (58%), Gaps = 2/80 (2%)
Query: 152 FDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIP-SKHSWHSFIQNCPS 210
+DY+++ ++FV QIRRM+ L++ + ++ ++ +L P S + + I P
Sbjct: 234 YDYYNVTIVAKSFVREQIRRMMSCLVNYSYDRIPLTTIEWLLSNPISSNFFDLGIPVAPP 293
Query: 211 DGLYLCEVEYDPKDLFYDPD 230
GL+L +V YDP+ +F +P+
Sbjct: 294 QGLFLTDVVYDPR-MFTNPE 312
>UniRef50_Q17C60 Cluster: Pseudouridylate synthase; n=2;
Culicidae|Rep: Pseudouridylate synthase - Aedes aegypti
(Yellowfever mosquito)
Length = 467
Score = 48.4 bits (110), Expect = 2e-04
Identities = 42/163 (25%), Positives = 71/163 (43%), Gaps = 15/163 (9%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
+F +I+ KE L G HDF K D R + V+I +
Sbjct: 202 YFFPRGSLNIDAMKEACTFLVGAHDFRNLCKMDVGNGVVTFTRRISYVSIE------DSQ 255
Query: 145 TESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI---PSKHSW 201
++++ S +D +E G+AF+ +Q+R ++ L V GK +P VK +L + P K
Sbjct: 256 SDAKESPYDMLYLELRGKAFLWHQVRCIMAVLFLVGEGKEEPSVVKELLDVNKNPCKPQ- 314
Query: 202 HSFIQNCPSDGLYLCEV----EYDPKDLFYDPDTTVESETLVE 240
+S + P + LY CE +DPK + + E + +
Sbjct: 315 YSLASDLPLN-LYECEYLNKGTFDPKSFDKNAPVLEDDEEIAD 356
>UniRef50_Q7TU07 Cluster: tRNA pseudouridine synthase A; n=1;
Pirellula sp.|Rep: tRNA pseudouridine synthase A -
Rhodopirellula baltica
Length = 276
Score = 48.4 bits (110), Expect = 2e-04
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 15/142 (10%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D + A G HDF F Q R TI + + + T G+
Sbjct: 143 DHSAMQSAAAKFVGRHDFKAF-------QGTGAERPSTVRTIHSARWIPRVATGPTGAEL 195
Query: 153 D--YWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
+ +W E G F++N +R ++GT++ V GK P+ + +L + P
Sbjct: 196 EGEHWCFEIDGEGFLYNMVRNLMGTMLEVGRGKKSPNWIDEVL---ASRDRKMAGPTAPP 252
Query: 211 DGLYLCEVEYDPKDLFY--DPD 230
GL+LC V+Y P ++F +PD
Sbjct: 253 QGLFLCRVDY-PDEVFQVEEPD 273
>UniRef50_Q8R7Y7 Cluster: tRNA pseudouridine synthase A; n=9;
Clostridia|Rep: tRNA pseudouridine synthase A -
Thermoanaerobacter tengcongensis
Length = 240
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/128 (28%), Positives = 58/128 (45%), Gaps = 19/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+E K+ A G HDFS FK N++ + K + E G
Sbjct: 132 DVEAMKKAAFFFRGTHDFSAFKA-------SGNKK------VNPVKTIFDLTVEKEG--- 175
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
D IE F++N +R +VGTL+ V +GK++ ++ +++ SK + I P G
Sbjct: 176 DLIKIEVEADGFLYNMVRIIVGTLVYVGLGKIKAGEIPAIIE--SKDRTKAGI-TAPPQG 232
Query: 213 LYLCEVEY 220
LYL + Y
Sbjct: 233 LYLVRIVY 240
>UniRef50_A6Q408 Cluster: Pseudouridylate synthase; n=2;
unclassified Epsilonproteobacteria|Rep: Pseudouridylate
synthase - Nitratiruptor sp. (strain SB155-2)
Length = 241
Score = 47.6 bits (108), Expect = 3e-04
Identities = 42/140 (30%), Positives = 65/140 (46%), Gaps = 20/140 (14%)
Query: 81 WKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPV 140
++ + ++ DIE K EG HDF F K + KS R K
Sbjct: 122 FENAYLHHVSNLDIEIIKRNISLFEGRHDFRYFMKTGS---------DTKSSVRRIFK-- 170
Query: 141 VTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHS 200
TA E D + + F G F+ QIR +VG LI + G+L+P+ +++ Q+ K
Sbjct: 171 -TALYEKD----DLYVLYFEGDGFLRAQIRLIVGALIKLGKGELKPE--QIIDQLACKAR 223
Query: 201 WHSFIQNCPSDGLYLCEVEY 220
+ S + P +GLYLC++ Y
Sbjct: 224 YTSTL--APPNGLYLCKIIY 241
>UniRef50_A5WGT0 Cluster: Pseudouridylate synthase; n=4;
Moraxellaceae|Rep: Pseudouridylate synthase -
Psychrobacter sp. PRwf-1
Length = 302
Score = 47.6 bits (108), Expect = 3e-04
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 19/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+ ++ A+H+ G HDFS+F+ Q K R + + H E F
Sbjct: 171 DLALMQQAAEHIVGTHDFSSFRA--AACQSKQPVRNIHHAKL-------FKHGE-----F 216
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+DI+ G F+H+ +R ++GTL ++ G+LQP+D +LQ + P DG
Sbjct: 217 IVFDIQADG--FLHHMVRNLMGTLFAIGKGELQPEDYLRILQAKDR---TIAPPTAPPDG 271
Query: 213 LYLCEVEY 220
LY Y
Sbjct: 272 LYFINAYY 279
>UniRef50_Q88XU9 Cluster: tRNA pseudouridine synthase A; n=10;
Lactobacillales|Rep: tRNA pseudouridine synthase A -
Lactobacillus plantarum
Length = 262
Score = 47.6 bits (108), Expect = 3e-04
Identities = 45/153 (29%), Positives = 69/153 (45%), Gaps = 20/153 (13%)
Query: 78 VEEWKRCHFIRLAEF--DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIR 135
V+ +KR H+ +F DI++ ++ LEG HDFSTF H H RE+ S
Sbjct: 124 VDPFKR-HYTGHFKFAADIDRIQQAIGDLEGRHDFSTFVASGS-QAHDH-VREIYSAK-- 178
Query: 136 AGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
A + R F EF G F++NQ+R MV L+ + G+ D + +L
Sbjct: 179 -----AWALPDEREIQF-----EFCGSGFLYNQVRIMVAVLMEIGQGRRAVDCIPALLAA 228
Query: 196 PSKHSWHSFIQNCPSDGLYLCEVEYDPKDLFYD 228
+ P+ GLY+ +V Y+ +L D
Sbjct: 229 KDREQARG---TAPAAGLYMKKVYYEQNELQAD 258
>UniRef50_A3ZQX0 Cluster: Pseudouridylate synthase; n=2;
Bacteria|Rep: Pseudouridylate synthase - Blastopirellula
marina DSM 3645
Length = 260
Score = 47.2 bits (107), Expect = 4e-04
Identities = 38/138 (27%), Positives = 61/138 (44%), Gaps = 16/138 (11%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
E + + A+HL G HDF++F+ + T+R V +E
Sbjct: 139 ELNFAAMQAAAQHLIGEHDFASFESVGSE----------RMTTVRHVFDVQVLRSERH-- 186
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
FD IE F++N +R +VGTL+ V G+ P+ V +L + + P+
Sbjct: 187 EFDKVAIEVEANGFLYNMVRIIVGTLVDVGKGRRPPEWVAEVLAAKKRTAGG---MTAPA 243
Query: 211 DGLYLCEVEYDPKDLFYD 228
GLYL V+Y P+ + D
Sbjct: 244 HGLYLLRVDY-PETCWLD 260
>UniRef50_A7SJV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 464
Score = 46.8 bits (106), Expect = 5e-04
Identities = 39/153 (25%), Positives = 64/153 (41%), Gaps = 9/153 (5%)
Query: 90 AEFDIEKFKEGAKHLEGYHDFSTFKKFD---KLLQHKHNRRELKSVTIRAGKPVVTAHTE 146
A DI+ +K LEG HDF F K D ++Q N K + +
Sbjct: 223 ANLDIDLMNLASKKLEGEHDFRNFCKMDVANGVIQFTRNITSFKVQKVSNATYSAPGENK 282
Query: 147 SRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPS--KHSWHSF 204
++ ++ + G AF+ +Q+R M+ L+ V G QP+ + +L I + ++
Sbjct: 283 AKQRGYEMCEAVICGSAFLWHQVRCMMSILLMVGQGLEQPEVIDWLLDIEKCPQRPQYNM 342
Query: 205 IQNCPSDGLYLCEVEYDPKDLFYDPDTTVESET 237
P L L + Y+ YDP +ES T
Sbjct: 343 ASELP---LVLYDCVYEGITWIYDPQ-VLESVT 371
>UniRef50_A2DE30 Cluster: tRNA pseudouridine synthase family
protein; n=1; Trichomonas vaginalis G3|Rep: tRNA
pseudouridine synthase family protein - Trichomonas
vaginalis G3
Length = 345
Score = 46.8 bits (106), Expect = 5e-04
Identities = 25/61 (40%), Positives = 37/61 (60%), Gaps = 5/61 (8%)
Query: 160 HGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVE 219
HG +F+ NQIR+M+ T+IS + + ++VK L S+ W I+ CP DGL L V+
Sbjct: 222 HGESFMLNQIRKMIATVISASHNYIGAEEVKRCL---SEEGWS--IKMCPGDGLMLDHVD 276
Query: 220 Y 220
Y
Sbjct: 277 Y 277
>UniRef50_Q8ZXR6 Cluster: tRNA pseudouridine synthase A; n=4;
Pyrobaculum|Rep: tRNA pseudouridine synthase A -
Pyrobaculum aerophilum
Length = 256
Score = 46.8 bits (106), Expect = 5e-04
Identities = 41/131 (31%), Positives = 62/131 (47%), Gaps = 19/131 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D++ +E AK L G HD+S+F + L KH +VT V RG
Sbjct: 104 DVDVMREAAKLLTGTHDYSSFIQ---LRGEKHT----PTVTT-----VYDIDVTLRG--- 148
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
D I F GR F + IR+M L++ G L DD+ +L+ P + + + P++G
Sbjct: 149 DLIFIYFAGRGFRNKMIRKMAWALLAAGRGVLSVDDLADLLKKPRPGA----VPSAPAEG 204
Query: 213 LYLCEVEYDPK 223
L L ++ YD K
Sbjct: 205 LVLLDIVYDVK 215
>UniRef50_Q1N6P3 Cluster: Pseudouridylate synthase; n=2;
Gammaproteobacteria|Rep: Pseudouridylate synthase -
Oceanobacter sp. RED65
Length = 297
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/128 (28%), Positives = 61/128 (47%), Gaps = 19/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D EK E A++L G HDF++F+ D Q +H R +K ++++
Sbjct: 165 DAEKMHEAAQYLLGEHDFTSFRAKD--CQARHAVRTMKYISVK--------------RLN 208
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
D+ +E AF+++ +R +VG L+ + GK +P V+ Q+ + P +G
Sbjct: 209 DWVIVEVCANAFLYHMVRNIVGVLLPIGEGK-KP--VEWCEQVLAAQDRRQAGVTAPGEG 265
Query: 213 LYLCEVEY 220
LY VEY
Sbjct: 266 LYFVNVEY 273
>UniRef50_Q6I4Q2 Cluster: tRNA pseudouridine synthase A 1; n=14;
Bacillaceae|Rep: tRNA pseudouridine synthase A 1 -
Bacillus anthracis
Length = 247
Score = 46.4 bits (105), Expect = 6e-04
Identities = 24/63 (38%), Positives = 37/63 (58%), Gaps = 3/63 (4%)
Query: 159 FHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEV 218
F G F++N +R +VGTL++V GKL PD + +I +K + + P GLYL +V
Sbjct: 187 FVGNGFLYNMVRIIVGTLLNVGQGKLDPDSIP---EILAKQNRQFAGKMAPGHGLYLWQV 243
Query: 219 EYD 221
Y+
Sbjct: 244 NYN 246
>UniRef50_Q74L59 Cluster: tRNA pseudouridine synthase A; n=18;
Bacilli|Rep: tRNA pseudouridine synthase A -
Lactobacillus johnsonii
Length = 263
Score = 46.0 bits (104), Expect = 9e-04
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 17/129 (13%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
DI K+ AK L G HDF++F + K R + V I T + + F
Sbjct: 139 DISLMKQAAKDLIGEHDFTSFAASGGQIVDKV--RTIYYVNI-------TPDPDKKQIIF 189
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
D F G F++N +R +VGTL+ + K DD+ +L+ + + P+ G
Sbjct: 190 D-----FIGNGFLYNMVRILVGTLLEIGNKKRPVDDIPRVLKAKDRQEVRT---TAPASG 241
Query: 213 LYLCEVEYD 221
LYL +V Y+
Sbjct: 242 LYLQQVFYE 250
>UniRef50_Q47HQ7 Cluster: Pseudouridylate synthase; n=1;
Dechloromonas aromatica RCB|Rep: Pseudouridylate
synthase - Dechloromonas aromatica (strain RCB)
Length = 262
Score = 45.6 bits (103), Expect = 0.001
Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 19/138 (13%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
++E +E L G HDFS F+ + Q K + + +R G+ F
Sbjct: 135 ELEAMQEACLRLLGEHDFSAFRAAN--CQAKSPVKHMSRAEVR-----------QCGNMF 181
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ +F AF+H+ +R +VGTL+ + G QPD ++ +LQ + DG
Sbjct: 182 VF---DFEASAFLHHMVRNLVGTLVYIGKGTQQPDWIEALLQTKDR---KLAAPTFSPDG 235
Query: 213 LYLCEVEYDPKDLFYDPD 230
LY Y+P DP+
Sbjct: 236 LYFRGPVYEPHWGLPDPN 253
>UniRef50_A5CET3 Cluster: Pseudouridylate synthase; n=1; Orientia
tsutsugamushi Boryong|Rep: Pseudouridylate synthase -
Orientia tsutsugamushi (strain Boryong) (Rickettsia
tsutsugamushi)
Length = 284
Score = 45.2 bits (102), Expect = 0.001
Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query: 123 KHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIE--FHGRAFVHNQIRRMVGTLISVA 180
KH+ +S +A P+ T T+ +Y +I+ F +F+H+ +R +VGTL+ +
Sbjct: 189 KHDFTSFRSSACQAKSPLKTL-TKIEVDTTNYPEIQIYFSAPSFLHHMVRNIVGTLVYIG 247
Query: 181 IGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
+ K+ P +K +L ++ PS GLY +V+Y
Sbjct: 248 LCKISPAAIKTILFAKNRAMAG---PTAPSSGLYFVKVDY 284
>UniRef50_A5PKS2 Cluster: LOC100101318 protein; n=4; Xenopus|Rep:
LOC100101318 protein - Xenopus laevis (African clawed
frog)
Length = 507
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 5/106 (4%)
Query: 90 AEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRG 149
A+ D+E + A+ LEG HDF K D + R + S R G PV +
Sbjct: 182 AQLDVEAMDKAARLLEGTHDFRNLCKMDVANGVLNFTRTVLSA--RVG-PVPEIPGDM-- 236
Query: 150 SAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
F + ++ G AF+++Q+R ++G L V GK +P+ + +L +
Sbjct: 237 GPFQLYHLQITGLAFLYHQVRCIMGVLFLVGQGKEKPEVITELLDV 282
>UniRef50_UPI000049A0B0 Cluster: pseudouridine synthase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: pseudouridine
synthase - Entamoeba histolytica HM-1:IMSS
Length = 366
Score = 44.4 bits (100), Expect = 0.003
Identities = 38/139 (27%), Positives = 64/139 (46%), Gaps = 18/139 (12%)
Query: 90 AEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRG 149
+ +D+ K KE A+ G HDF+ F K D + H R + S + E+ G
Sbjct: 179 SSYDVPKMKEAAQLFLGEHDFTNFCKKDPAVSHCVRR--VNSFEVE----------ETDG 226
Query: 150 SAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCP 209
+ G AFV +Q+R MVG L ++ G P+ +K +L + ++ ++ + P
Sbjct: 227 LS----RFVVCGTAFVWHQVRYMVGALFAIGQG-ANPESIKQLLDV-EHYTKPNYFKYAP 280
Query: 210 SDGLYLCEVEYDPKDLFYD 228
+ L L E +YD + D
Sbjct: 281 AYPLVLYECKYDGVEFLCD 299
>UniRef50_Q0F2X2 Cluster: Pseudouridylate synthase; n=1;
Mariprofundus ferrooxydans PV-1|Rep: Pseudouridylate
synthase - Mariprofundus ferrooxydans PV-1
Length = 267
Score = 44.4 bits (100), Expect = 0.003
Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 24/153 (15%)
Query: 78 VEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAG 137
++ W+ H+ +IE + A H G HDFS + Q H + ++S+ I
Sbjct: 134 LQRWR--HWWMPRSLNIEAMQGAAVHCLGRHDFSALRAAG--CQAAHAEKHIRSLEIVQH 189
Query: 138 KPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPS 197
+ H + AF+++ +R +VG L+ V GK PDD +L
Sbjct: 190 GHCIHIHVSA--------------DAFLYHMVRNLVGNLVEVGAGKRSPDDFAALLASRD 235
Query: 198 KHSWHSFIQNCPSDGLYLCEVEYDPKDLFYDPD 230
+ + P+ GLY + YD FY D
Sbjct: 236 RQLGAA---TAPAHGLYFTDAWYDD---FYSRD 262
>UniRef50_A6TWE8 Cluster: Pseudouridylate synthase; n=4;
Clostridia|Rep: Pseudouridylate synthase - Alkaliphilus
metalliredigens QYMF
Length = 255
Score = 44.4 bits (100), Expect = 0.003
Identities = 33/130 (25%), Positives = 68/130 (52%), Gaps = 19/130 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
+ D++K K+ ++ L G HDF F + ++KS T+R + + +++GS
Sbjct: 134 KLDLQKMKQASETLLGTHDFKGFMA---------SGSQVKS-TVRR---IDEINFDTQGS 180
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
W I G F++ +R +VG+L+ + GK++ + ++ +L+ ++ ++ P+
Sbjct: 181 QI--W-ITMQGNGFLYKMVRIIVGSLVGIGTGKIKEEALQNILETQNR---RVAVKTAPA 234
Query: 211 DGLYLCEVEY 220
GLYL +V Y
Sbjct: 235 QGLYLQKVFY 244
>UniRef50_A4CLB7 Cluster: TRNA pseudouridine synthase A; n=1;
Robiginitalea biformata HTCC2501|Rep: TRNA pseudouridine
synthase A - Robiginitalea biformata HTCC2501
Length = 274
Score = 44.4 bits (100), Expect = 0.003
Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPV--VTAHTESRG- 149
DI + +E A EG H+F F + K R + + G P+ V A + G
Sbjct: 144 DITRMREAAPLFEGMHNFRCFTASPS--EDKKYVRRVTRCRLGVGSPMDGVVAGKDPEGD 201
Query: 150 SAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCP 209
+ F +E F NQ+R M+ L +V +LQP+ + +L W S P
Sbjct: 202 TGFTAHMLEVRAPGFGRNQVRLMMAALAAVGRQELQPETLVKVLD--EGQGWMS-DSIVP 258
Query: 210 SDGLYLCEVEY 220
+ GL+L VE+
Sbjct: 259 ASGLHLMHVEF 269
>UniRef50_Q9KTA4 Cluster: tRNA pseudouridine synthase A; n=29;
Gammaproteobacteria|Rep: tRNA pseudouridine synthase A -
Vibrio cholerae
Length = 264
Score = 44.4 bits (100), Expect = 0.003
Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 19/130 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
E D+EK ++ ++L G +DF++F+ H +R ++V VT H
Sbjct: 133 ELDVEKMQQAGQYLLGENDFTSFRAV-----HCQSRSPWRNVMHLN----VTRHGR---- 179
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
Y I+ AFVH+ +R + G+LI+V G+ +P+ ++ +L ++ +
Sbjct: 180 ---YVVIDIKANAFVHHMVRNITGSLIAVGRGEQKPEWIQWLL---AQKDRTLAAATAKA 233
Query: 211 DGLYLCEVEY 220
+GLYL V+Y
Sbjct: 234 EGLYLVSVDY 243
>UniRef50_O26928 Cluster: tRNA pseudouridine synthase A; n=1;
Methanothermobacter thermautotrophicus str. Delta H|Rep:
tRNA pseudouridine synthase A - Methanobacterium
thermoautotrophicum
Length = 275
Score = 44.4 bits (100), Expect = 0.003
Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 24/148 (16%)
Query: 77 PVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTI-R 135
P+E R R D E A H G HDFS F + + R + V I
Sbjct: 104 PLERHYRYILHREESMDTYSMAEAAAHFRGTHDFSNFSR----RSDRDPVRRINDVRISE 159
Query: 136 AGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
G ++ I+ +G +F+ +R+MV L+ V+ G+L PDD+ +L
Sbjct: 160 VGDSII---------------IDVYGESFLWQMVRKMVRALLMVSEGELAPDDMAGLLDT 204
Query: 196 PSKHSWHSFIQNCPSDGLYLCEVEYDPK 223
+ F++ P + L L +++Y K
Sbjct: 205 DRR----VFLEPMPPENLILMDLKYGVK 228
>UniRef50_P60350 Cluster: tRNA pseudouridine synthase A; n=6;
Desulfuromonadales|Rep: tRNA pseudouridine synthase A -
Geobacter sulfurreducens
Length = 244
Score = 44.0 bits (99), Expect = 0.003
Identities = 30/104 (28%), Positives = 49/104 (47%), Gaps = 16/104 (15%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
++ +E A+HL G DF++F+ + R + +V I ++T
Sbjct: 136 NLAAMREAARHLTGERDFASFRTAG--CAARTTIRRVDAVEISDDGEMLT---------- 183
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIP 196
++ HG F+ N +R MVGTL+ V GKL P+ V M+ P
Sbjct: 184 ----VDVHGSGFLRNMVRIMVGTLVEVGRGKLTPEHVAQMVVCP 223
>UniRef50_Q8XXX8 Cluster: tRNA pseudouridine synthase A; n=50;
Betaproteobacteria|Rep: tRNA pseudouridine synthase A -
Ralstonia solanacearum (Pseudomonas solanacearum)
Length = 274
Score = 43.6 bits (98), Expect = 0.005
Identities = 30/113 (26%), Positives = 56/113 (49%), Gaps = 5/113 (4%)
Query: 109 DFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH-TESRGSAFDYWDIEFHGRAFVHN 167
D + + ++L +H+ ++ +A PV T + TE RG ++ + G AF+H+
Sbjct: 140 DVTAMHEAAQVLVGEHDFSSFRAAECQAKSPVKTMYSTEVRGQG-EWVFVRIRGSAFLHH 198
Query: 168 QIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
+R ++G L+++ GK +P M ++ + + DGLYL EV Y
Sbjct: 199 MVRNIMGCLVAIGRGK-RP--AAWMGEVLAARDRKAAAPTFMPDGLYLAEVGY 248
>UniRef50_Q5L3Q7 Cluster: tRNA pseudouridine synthase A; n=11;
Bacillaceae|Rep: tRNA pseudouridine synthase A -
Geobacillus kaustophilus
Length = 258
Score = 43.6 bits (98), Expect = 0.005
Identities = 32/134 (23%), Positives = 59/134 (44%), Gaps = 19/134 (14%)
Query: 94 IEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFD 153
I E + L G HDF++F ++ + R + ++A P++
Sbjct: 139 ISAMNEALRLLHGTHDFTSFCSAKTSIEDRV--RTMYRAEVKADGPML------------ 184
Query: 154 YWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGL 213
+ F G F++N +R +VGT++ + GK P D+ +L + P++GL
Sbjct: 185 --EFRFVGSGFLYNMVRIIVGTVLEIGQGKRSPADISTLLAAKDRRLAG---PTAPAEGL 239
Query: 214 YLCEVEYDPKDLFY 227
YL V Y+ + L +
Sbjct: 240 YLWRVYYEDECLVH 253
>UniRef50_A7F2S8 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 592
Score = 43.2 bits (97), Expect = 0.006
Identities = 34/119 (28%), Positives = 48/119 (40%), Gaps = 16/119 (13%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
DIE +E AK EG HDF F K D Q + R + I K ++ G +F
Sbjct: 293 DIEAMREAAKLYEGLHDFRNFCKVDPGKQITNFERRIFYANIEEVKDYTSSLAYVNGDSF 352
Query: 153 ----------------DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
+ + HG AF+ +Q+R MV L V G +P V +L +
Sbjct: 353 LDDSIRSKIDGESKAPKVYTFDLHGSAFLWHQVRHMVAILFLVGQGLEKPSVVSELLDV 411
>UniRef50_A2QE34 Cluster: Catalytic activity: tRNA uridine <=> tRNA
pseudouridine; n=1; Aspergillus niger|Rep: Catalytic
activity: tRNA uridine <=> tRNA pseudouridine -
Aspergillus niger
Length = 517
Score = 43.2 bits (97), Expect = 0.006
Identities = 32/109 (29%), Positives = 49/109 (44%), Gaps = 11/109 (10%)
Query: 87 IRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTE 146
+R DIE ++ AK+ EG HDF F K D Q + R++ + P+ T
Sbjct: 255 LREGWLDIEAMRKAAKYFEGTHDFRNFCKLDVTKQIESFYRDIFQ---SSAAPLPT---- 307
Query: 147 SRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
A + G AF+ +Q+R MV L V G +P V+ +L +
Sbjct: 308 ----AAQVYVFHLEGSAFLWHQVRHMVNVLFLVGQGLEEPSIVQDLLDV 352
>UniRef50_Q1Q1P7 Cluster: Pseudouridylate synthase; n=1; Candidatus
Kuenenia stuttgartiensis|Rep: Pseudouridylate synthase -
Candidatus Kuenenia stuttgartiensis
Length = 244
Score = 42.7 bits (96), Expect = 0.008
Identities = 34/128 (26%), Positives = 64/128 (50%), Gaps = 19/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+ K A++L G HDF++F K L +K R +K++ I+ + +
Sbjct: 136 DLSKMMTAAQYLIGTHDFTSFTT--KALDNKDRIRTIKNLEIQ------------KEGKY 181
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
Y+ +E +G F++ +R +VGTL+ + GK+ DV ++ ++ + P+ G
Sbjct: 182 IYFVVEANG--FLYKMVRTIVGTLLEIGRGKM---DVYLIRKLLETGNRDDAGPTAPAKG 236
Query: 213 LYLCEVEY 220
L + EV+Y
Sbjct: 237 LCMKEVKY 244
>UniRef50_A5D5F5 Cluster: Pseudouridylate synthase; n=2;
Clostridia|Rep: Pseudouridylate synthase - Pelotomaculum
thermopropionicum SI
Length = 273
Score = 42.3 bits (95), Expect = 0.011
Identities = 39/128 (30%), Positives = 61/128 (47%), Gaps = 19/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+E + GA L G HDFS F+ ++ R L++ R G V
Sbjct: 164 DVEAMQAGAALLIGRHDFSAFRALGTPVKSTV-RTMLEACVSREGDLV------------ 210
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
Y D++ G F+++ R + GTLI V +GK+ P +V +L+ S+ S P+ G
Sbjct: 211 -YIDLKADG--FLYHMARMIAGTLIRVGLGKIPPGEVAAILK--SRDSLRGG-PTAPARG 264
Query: 213 LYLCEVEY 220
L L ++EY
Sbjct: 265 LCLEKIEY 272
>UniRef50_A4ARQ7 Cluster: Pseudouridylate synthase; n=2;
Flavobacteriales|Rep: Pseudouridylate synthase -
Flavobacteriales bacterium HTCC2170
Length = 282
Score = 42.3 bits (95), Expect = 0.011
Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 10/133 (7%)
Query: 89 LAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESR 148
L E D+E K+ A G HD S + K + H +R + S I K + +
Sbjct: 160 LDELDLELMKKAASLYVGTHDLSVYTV--KAQNNAHKKRTITSCEIIENKILQANFFPEK 217
Query: 149 GSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNC 208
AF G F+ QIR M+G LI + G+L D++ L P +++
Sbjct: 218 SYAF-----RVEGPGFMRYQIRMMMGALIQLGKGELLFADIENSLSNPESIEL-TYV--A 269
Query: 209 PSDGLYLCEVEYD 221
P GL L ++ D
Sbjct: 270 PGSGLLLNRLDLD 282
>UniRef50_Q2NHB4 Cluster: Pseudouridylate synthase; n=1;
Methanosphaera stadtmanae DSM 3091|Rep: Pseudouridylate
synthase - Methanosphaera stadtmanae (strain DSM 3091)
Length = 274
Score = 42.3 bits (95), Expect = 0.011
Identities = 20/60 (33%), Positives = 37/60 (61%), Gaps = 1/60 (1%)
Query: 161 GRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
G +F+ N +R+MV +++ V GKL +D+ +L+ P + +Q P++GL L ++EY
Sbjct: 174 GESFLWNMVRKMVTSIMEVGYGKLDINDINELLK-PKELRQFIRLQPAPANGLILSDMEY 232
>UniRef50_Q9RS37 Cluster: tRNA pseudouridine synthase A; n=2;
Deinococcus|Rep: tRNA pseudouridine synthase A -
Deinococcus radiodurans
Length = 280
Score = 42.3 bits (95), Expect = 0.011
Identities = 35/128 (27%), Positives = 57/128 (44%), Gaps = 21/128 (16%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D E A+ L G HDF+ F R + ++V + ++ + +G
Sbjct: 153 DAEAMNRAAQSLIGLHDFAAFA----------TREDRQTV-----RDLLRLEVQPQG--- 194
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ WDI G +F+ + +R +VGTL+ V GKL +V+ +L + + N P G
Sbjct: 195 ELWDIHVAGESFLRHMVRGLVGTLLLVGQGKLGAAEVEGILASRERARAGA---NVPPGG 251
Query: 213 LYLCEVEY 220
LY EY
Sbjct: 252 LYFAGAEY 259
>UniRef50_Q1YHJ2 Cluster: Pseudouridylate synthase; n=2;
Alphaproteobacteria|Rep: Pseudouridylate synthase -
Aurantimonas sp. SI85-9A1
Length = 259
Score = 41.9 bits (94), Expect = 0.014
Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 18/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D++ A+ L G HDF TF+ Q K+ R L+ + + G P H
Sbjct: 137 DVDAMHAAAQRLVGTHDFDTFRSAH--CQAKNPIRTLEQLDVVRG-PGEEIH-------- 185
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
I ++F+HNQIR G+L V G D+ L+ + P DG
Sbjct: 186 ----IHAMAQSFLHNQIRSFAGSLKLVGEGHWSAADLVAALEARDRKRCGPV---APPDG 238
Query: 213 LYLCEVEY 220
LYL VEY
Sbjct: 239 LYLTRVEY 246
>UniRef50_Q8DWH1 Cluster: tRNA pseudouridine synthase A; n=42;
Lactobacillales|Rep: tRNA pseudouridine synthase A -
Streptococcus mutans
Length = 249
Score = 41.9 bits (94), Expect = 0.014
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 5/123 (4%)
Query: 101 AKHLEGYHDFSTFKKFDKLLQHKHNRRELKS--VTIRAGKPVVTAHTESRGSAFDYWDIE 158
A H DFS K K L+ H+ + ++ ++ T + +
Sbjct: 129 ATHFPYKVDFSVVKAAIKKLRGTHDFTGFTASGTSVENKVRTISRATVEKDDKTGFLIFT 188
Query: 159 FHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEV 218
F G F++ Q+R MVGTL+ + G++ D + +L+ + S+GLYL E+
Sbjct: 189 FTGSGFLYKQVRNMVGTLLKIGNGRMPIDQIDRILESGDRSLAG---PTAASNGLYLKEI 245
Query: 219 EYD 221
YD
Sbjct: 246 IYD 248
>UniRef50_Q5FPX3 Cluster: tRNA pseudouridine synthase A; n=4;
Rhodospirillales|Rep: tRNA pseudouridine synthase A -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 275
Score = 41.9 bits (94), Expect = 0.014
Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 20/134 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D++ ++ A HL G HDF++F ++V +A P+ T +
Sbjct: 159 DVDLMQQAANHLLGPHDFTSF----------------RAVACQARSPIRTLDVLNIHRDG 202
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ I+ R+F+H+Q+R M GTL + IG Q K++ + +K + Q P +G
Sbjct: 203 ELVMIDTKARSFLHHQVRNMAGTL--MMIGSRQWPVEKIIEILEAKDRCAAG-QTAPPEG 259
Query: 213 LYLCEVEYDPKDLF 226
L L +V Y P D F
Sbjct: 260 LCLMDVGY-PDDPF 272
>UniRef50_O28544 Cluster: tRNA pseudouridine synthase A; n=1;
Archaeoglobus fulgidus|Rep: tRNA pseudouridine synthase
A - Archaeoglobus fulgidus
Length = 265
Score = 41.9 bits (94), Expect = 0.014
Identities = 37/139 (26%), Positives = 60/139 (43%), Gaps = 19/139 (13%)
Query: 90 AEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRG 149
+++DI ++ K L G HDFS F K K + + RE+ S IRA + +
Sbjct: 112 SDYDISAMRKAVKELIGVHDFSNFTK--KFGEGESCVREIISADIRADREFII------- 162
Query: 150 SAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCP 209
E G AF N +R +V ++ + + + +L P KH ++ P
Sbjct: 163 -------FEIEGNAFTWNMVRCIVTAIMEIGKQHRSIEWFRDLLN-PEKHK--ERVEPAP 212
Query: 210 SDGLYLCEVEYDPKDLFYD 228
GL L +V+YD + D
Sbjct: 213 PYGLILKDVKYDDVEFEID 231
>UniRef50_A7AKE9 Cluster: Putative uncharacterized protein; n=2;
Bacteroidales|Rep: Putative uncharacterized protein -
Parabacteroides merdae ATCC 43184
Length = 297
Score = 41.5 bits (93), Expect = 0.018
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
D W F+ N +R +VGTL+ V GKL D + +++ + + + P
Sbjct: 222 DVWVFTIQADRFLRNMVRAIVGTLLEVGRGKLTVDGFRQVIEAKDRGRAGT---SAPGHA 278
Query: 213 LYLCEVEYDPKDLF 226
LYL +V Y P++LF
Sbjct: 279 LYLVDVTY-PEELF 291
>UniRef50_A2ZIV2 Cluster: Pseudouridylate synthase; n=2; Oryza
sativa|Rep: Pseudouridylate synthase - Oryza sativa
subsp. indica (Rice)
Length = 257
Score = 41.5 bits (93), Expect = 0.018
Identities = 23/60 (38%), Positives = 36/60 (60%), Gaps = 3/60 (5%)
Query: 162 RAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYD 221
R+F+++Q+R MVG L SV G L +DV+ +L + + + P+ GLYL V+YD
Sbjct: 198 RSFLYHQVRLMVGLLKSVGTGDLTTEDVERILNLKAVTAAPPM---APACGLYLANVKYD 254
>UniRef50_Q8I0W4 Cluster: TRNA pseudouridine synthase, putative;
n=6; Plasmodium|Rep: TRNA pseudouridine synthase,
putative - Plasmodium falciparum (isolate 3D7)
Length = 304
Score = 41.5 bits (93), Expect = 0.018
Identities = 38/109 (34%), Positives = 52/109 (47%), Gaps = 15/109 (13%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
+F ++IEK K+ AK G HDFS K K + NRR + IR + H
Sbjct: 117 YFFINKNYNIEKMKKAAKLFIGEHDFSNCCKKGKNVTS--NRRTVLKFDIRN----IDKH 170
Query: 145 TESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVML 193
F Y+ I+ G +F++NQIR MV L V G L +DV +L
Sbjct: 171 -------FYYFKIK--GISFLYNQIRHMVAILFLVGKGLLDNNDVNNIL 210
>UniRef50_Q54RR6 Cluster: Pseudouridylate synthase; n=1;
Dictyostelium discoideum AX4|Rep: Pseudouridylate
synthase - Dictyostelium discoideum AX4
Length = 343
Score = 41.5 bits (93), Expect = 0.018
Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 4/79 (5%)
Query: 146 ESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFI 205
+ + + Y+ IE RAF+HNQ+R MV +LI V G++ ++ + +I K +
Sbjct: 231 DKKNTGLQYFGIEIKARAFLHNQVRIMVASLIKVGEGEI---SIQQLEEIKDKKDRGAAP 287
Query: 206 QNCPSDGLYLCEVEY-DPK 223
+ L L V Y DPK
Sbjct: 288 PTASPEPLTLLTVSYDDPK 306
>UniRef50_Q8R601 Cluster: tRNA pseudouridine synthase A; n=3;
Fusobacterium nucleatum|Rep: tRNA pseudouridine synthase
A - Fusobacterium nucleatum subsp. nucleatum
Length = 247
Score = 41.5 bits (93), Expect = 0.018
Identities = 21/64 (32%), Positives = 39/64 (60%), Gaps = 3/64 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
I G AF+ +Q+R MVGT + + G+L + +++ML +K + ++ ++GLYL
Sbjct: 187 IYIKGSAFLKSQVRIMVGTALEIYYGRLLENHIRLMLNDFTKEYKKNLVE---AEGLYLN 243
Query: 217 EVEY 220
++EY
Sbjct: 244 KIEY 247
>UniRef50_UPI00004993EF Cluster: tRNA pseudouridine synthase; n=1;
Entamoeba histolytica HM-1:IMSS|Rep: tRNA pseudouridine
synthase - Entamoeba histolytica HM-1:IMSS
Length = 401
Score = 41.1 bits (92), Expect = 0.024
Identities = 28/133 (21%), Positives = 63/133 (47%), Gaps = 2/133 (1%)
Query: 111 STFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTES-RGSAFDYWDIEFHGRAFVHNQI 169
S + K + N +E K+ + + +++ + + + + + HG++F+ QI
Sbjct: 194 SNYVKTHNFQNYTFNTKETKADSKSNNRYIISMSAQLVQRNGLNVIAVSIHGQSFMLWQI 253
Query: 170 RRMVGTLISVAIGKLQPDDVKVMLQIP-SKHSWHSFIQNCPSDGLYLCEVEYDPKDLFYD 228
RRM+G I + +L + + +++ + +W S I P+ GL+L + + +
Sbjct: 254 RRMIGFAIVLTNFRLPIEQMNEIMKTSFTLINWRSVIPTAPAHGLFLDQCHFGNHNERLQ 313
Query: 229 PDTTVESETLVES 241
DT+ S+T + S
Sbjct: 314 RDTSNNSKTNINS 326
>UniRef50_Q3Y386 Cluster: Pseudouridylate synthase; n=3;
Firmicutes|Rep: Pseudouridylate synthase - Enterococcus
faecium DO
Length = 246
Score = 41.1 bits (92), Expect = 0.024
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 19/147 (12%)
Query: 74 NVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVT 133
NVIP + F E D++K + L G HDF F K K R + ++
Sbjct: 118 NVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSALKK--SKKSTVRTIDELS 175
Query: 134 IRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVML 193
I E +G + F G F++ +R ++GTL+ + G + + + +
Sbjct: 176 I-----------ERKGEMLHF---TFVGDGFLYKMVRIIMGTLLEIGTGAMPIETIDEIF 221
Query: 194 QIPSKHSWHSFIQNCPSDGLYLCEVEY 220
+ SK H+ + P+ GL+L EV Y
Sbjct: 222 E--SKVRQHAG-ETVPAQGLFLDEVYY 245
>UniRef50_A0B7V0 Cluster: Pseudouridylate synthase; n=1;
Methanosaeta thermophila PT|Rep: Pseudouridylate
synthase - Methanosaeta thermophila (strain DSM 6194 /
PT) (Methanothrixthermophila (strain DSM 6194 / PT))
Length = 267
Score = 41.1 bits (92), Expect = 0.024
Identities = 38/146 (26%), Positives = 62/146 (42%), Gaps = 25/146 (17%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
+F+ + D+ +E A HL G HDF F + R + S+ + A +V
Sbjct: 111 YFLFSPDIDLSAVREAAGHLVGTHDFRNFS-----MSKVDTVRRIISIDVNAHCGIVV-- 163
Query: 145 TESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSF 204
+D+ G F+ N +RR+VG L + IG+ D + +L + H
Sbjct: 164 ----------FDVRAEG--FIWNMVRRIVGALELIGIGEKPVDWILELLDPSTPHG---- 207
Query: 205 IQNCPSDGLYLCEVEYDPKDLFYDPD 230
P +GL L +V Y DL ++ D
Sbjct: 208 APTAPPEGLMLMDVGY--SDLEWEED 231
>UniRef50_A6C4N8 Cluster: Pseudouridylate synthase; n=1;
Planctomyces maris DSM 8797|Rep: Pseudouridylate
synthase - Planctomyces maris DSM 8797
Length = 267
Score = 40.7 bits (91), Expect = 0.032
Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 12/135 (8%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTI-RAGK-PV----VTAHTE 146
D ++ + L G HDF F+ + R + +T+ R G PV AH
Sbjct: 136 DSDRMHAAGQQLLGQHDFRCFESHYP--NKATSVRTITELTVQRTGVWPVWGVLEQAHLS 193
Query: 147 SRGS-AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFI 205
S + ++ ++ F++N +R +VGTL+ V +G+ +DV+ +L +
Sbjct: 194 MENSTSAEFITVDVVADGFLYNMVRAIVGTLLDVGVGRWTSNDVQKILTGMDRSQAG--- 250
Query: 206 QNCPSDGLYLCEVEY 220
P+ GLYL +V+Y
Sbjct: 251 PTAPACGLYLVQVDY 265
>UniRef50_Q011R7 Cluster: Exopolyphosphatases and related proteins;
n=3; Ostreococcus|Rep: Exopolyphosphatases and related
proteins - Ostreococcus tauri
Length = 813
Score = 40.7 bits (91), Expect = 0.032
Identities = 38/140 (27%), Positives = 53/140 (37%), Gaps = 14/140 (10%)
Query: 86 FIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHT 145
F + D+E E A+ EG HDF F + D +KS T R V+
Sbjct: 582 FEKTTALDLEAMGEAARAFEGVHDFRNFCRMD--------AENVKSFTRR----VLECTI 629
Query: 146 ESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFI 205
E G I G AF+ +Q+R M L V +G P V+ +L + +
Sbjct: 630 EEAGDG-KLMYINVRGTAFLWHQVRNMASVLFMVGLGHEPPSVVERLLDLERTPRKPQY- 687
Query: 206 QNCPSDGLYLCEVEYDPKDL 225
P + L L YD L
Sbjct: 688 PMAPEESLLLWRSGYDESRL 707
>UniRef50_Q5KC13 Cluster: Pseudouridylate synthase, putative; n=2;
Filobasidiella neoformans|Rep: Pseudouridylate synthase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 514
Score = 40.7 bits (91), Expect = 0.032
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
E D+E ++GA+ L G HD+ F K D Q +++ R + GK S+G
Sbjct: 261 ELDLELMRQGAQLLLGEHDYRNFCKLDGSKQIENHTRGVLKAWFEGGK--------SQGV 312
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDV 189
G AF+ +Q+R ++ L V KL+P +
Sbjct: 313 GDGMMVFNLIGTAFLWHQVRHIIAVLFLVG-AKLEPPSI 350
>UniRef50_Q2LWJ8 Cluster: Pseudouridylate synthase; n=1; Syntrophus
aciditrophicus SB|Rep: Pseudouridylate synthase -
Syntrophus aciditrophicus (strain SB)
Length = 328
Score = 40.3 bits (90), Expect = 0.043
Identities = 39/133 (29%), Positives = 58/133 (43%), Gaps = 18/133 (13%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
+++K + ++ G+HDFS+F DK + + R V + A TE S
Sbjct: 197 ELKKMQAASRLFAGFHDFSSFA--DKRMDKQAPTR----VKVEA--------TELHASG- 241
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
D G F+ +RRMVG ++ V KL DV+ ML+ +S P G
Sbjct: 242 DLIFFRVTGSHFLWKMVRRMVGVMVEVGREKLDISDVRQMLK---SYSPEPARLTAPPSG 298
Query: 213 LYLCEVEYDPKDL 225
LYL V Y+ L
Sbjct: 299 LYLERVLYEGDSL 311
>UniRef50_A3JGC0 Cluster: Pseudouridylate synthase; n=4;
Alteromonadales|Rep: Pseudouridylate synthase -
Marinobacter sp. ELB17
Length = 303
Score = 40.3 bits (90), Expect = 0.043
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 19/126 (15%)
Query: 95 EKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDY 154
E + A+ L G HDFS F+ Q R L+S+++ +G DY
Sbjct: 154 ENMHQAAQALVGEHDFSAFRAAG--CQSHSPIRFLQSISVTR-----------KG---DY 197
Query: 155 WDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLY 214
I+ AF+H+ +R + G L++V + PD + +L + P DGLY
Sbjct: 198 LVIDVQANAFLHHMVRNIAGALMAVGCQEQAPDWIGQILATKDRRQAG---VTAPPDGLY 254
Query: 215 LCEVEY 220
L +V Y
Sbjct: 255 LVDVGY 260
>UniRef50_A1HQP5 Cluster: Pseudouridylate synthase; n=1; Thermosinus
carboxydivorans Nor1|Rep: Pseudouridylate synthase -
Thermosinus carboxydivorans Nor1
Length = 250
Score = 40.3 bits (90), Expect = 0.043
Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 3/82 (3%)
Query: 139 PVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSK 198
PV T + D + F G F+++ +R +VGTL+ V +G+L D +L +
Sbjct: 172 PVRTIYEAGCTREGDMLEFRFWGNGFLYHMVRNLVGTLVDVGLGRLTRDGFTRIL--AGR 229
Query: 199 HSWHSFIQNCPSDGLYLCEVEY 220
+ I P GLYL E+ Y
Sbjct: 230 DRTRAGI-TAPPQGLYLKEIFY 250
>UniRef50_Q22TA6 Cluster: Pseudouridylate synthase; n=1; Tetrahymena
thermophila SB210|Rep: Pseudouridylate synthase -
Tetrahymena thermophila SB210
Length = 481
Score = 40.3 bits (90), Expect = 0.043
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 6/140 (4%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
+ DI++ KE A G HDF F K D +LQ + R + + I V A+ +
Sbjct: 228 QMDIQRMKEAANLFLGEHDFRNFCKID-VLQTLNYVRIIYQLDIEE----VQANFGTLDP 282
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
+ G AF+ +QIR M+ L V + +P V +L I S ++ + P
Sbjct: 283 RSKLYVATIQGSAFLWHQIRNMMAILFLVGRKQEEPSIVTELLDIQKNPSKPNY-EMAPD 341
Query: 211 DGLYLCEVEYDPKDLFYDPD 230
L L + Y+ Y D
Sbjct: 342 YPLVLFDCLYNNVSFNYSSD 361
>UniRef50_Q7NAQ9 Cluster: tRNA pseudouridine synthase A; n=1;
Mycoplasma gallisepticum|Rep: tRNA pseudouridine
synthase A - Mycoplasma gallisepticum
Length = 262
Score = 40.3 bits (90), Expect = 0.043
Identities = 32/113 (28%), Positives = 49/113 (43%), Gaps = 5/113 (4%)
Query: 109 DFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQ 168
DF+ +K +L+ HN T K + T H + I G F+ +
Sbjct: 155 DFNLIEKAIPILEGTHNFWSFS--TADKDKGLRTIHKIDLKQEDNKVYIYITGDGFLRSM 212
Query: 169 IRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYD 221
+R +VG L ++ I K + +K +L P K I P+ GLYL EV Y+
Sbjct: 213 VRMIVGALYNIGIKKYDLNHLKWLLDNPKK---GRAITKAPASGLYLYEVYYE 262
>UniRef50_Q4FNF9 Cluster: Pseudouridylate synthase; n=6;
Bacteria|Rep: Pseudouridylate synthase - Pelagibacter
ubique
Length = 246
Score = 39.9 bits (89), Expect = 0.056
Identities = 43/143 (30%), Positives = 68/143 (47%), Gaps = 21/143 (14%)
Query: 78 VEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAG 137
+E+ + H I+ + DIE K+G+K L G DFSTF+ K + +KSV I++
Sbjct: 125 LEKERGWHIIK--KLDIELMKKGSKKLLGTKDFSTFRASS--CNAKSPIKTMKSVNIKSK 180
Query: 138 KPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPS 197
+ +I+F ++F+ Q+R MVG+L +A K D K I S
Sbjct: 181 DGRI--------------EIQFKSQSFLQQQVRSMVGSLKYLAENKW--DLKKFEFVIKS 224
Query: 198 KHSWHSFIQNCPSDGLYLCEVEY 220
K P++GL+L +V Y
Sbjct: 225 KKR-ILCAPPAPAEGLFLEKVIY 246
>UniRef50_A7CTY5 Cluster: tRNA pseudouridine synthase A; n=1;
Opitutaceae bacterium TAV2|Rep: tRNA pseudouridine
synthase A - Opitutaceae bacterium TAV2
Length = 354
Score = 39.9 bits (89), Expect = 0.056
Identities = 21/57 (36%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 164 FVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
F++ +RR+VG L+ +GKL P D+ QI S+ I+ P+ GL+L V Y
Sbjct: 296 FLYRMVRRLVGALVHAGLGKLTPGDI---AQILSEARRTPRIETAPAHGLFLDRVFY 349
>UniRef50_A6FXP9 Cluster: Pseudouridylate synthase; n=1;
Plesiocystis pacifica SIR-1|Rep: Pseudouridylate
synthase - Plesiocystis pacifica SIR-1
Length = 285
Score = 39.9 bits (89), Expect = 0.056
Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 8/107 (7%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSV-----TIRAGKPVVTAHTES 147
D+ + A G HDF+ F+ D Q K R ++SV T+ P+
Sbjct: 143 DVAAMQAAAPRFAGTHDFAGFRASD--CQAKSTTRRVRSVIVNVETLAELDPLAGQRGRI 200
Query: 148 RGSAFDYW-DIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVML 193
G A I+ G AF+ N +R MVGTL+ V G+ + + +L
Sbjct: 201 EGPAAPARVTIDVRGDAFLKNMVRIMVGTLVGVGRGQFGAERIDEVL 247
>UniRef50_A6DH96 Cluster: Pseudouridylate synthase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Pseudouridylate
synthase - Lentisphaera araneosa HTCC2155
Length = 276
Score = 39.9 bits (89), Expect = 0.056
Identities = 34/131 (25%), Positives = 52/131 (39%), Gaps = 18/131 (13%)
Query: 95 EKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDY 154
EK ++ +HLEG HDFS F K LQ R K+ I G V
Sbjct: 141 EKMRQSLQHLEGKHDFSAFTVDRKNLQGHAIRTVFKAELIEIGHIVA------------- 187
Query: 155 WDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLY 214
+ F G F++ +R M G +++V + P L H P+ GL+
Sbjct: 188 --LLFTGDGFLYRMVRSMAGEVVNVGMEFQNPQHT---LDALESHQRSEAGVTAPAKGLF 242
Query: 215 LCEVEYDPKDL 225
L + Y +++
Sbjct: 243 LGQCYYSKEEM 253
>UniRef50_Q00ST8 Cluster: TRNA pseudouridylate synthase; n=2;
Ostreococcus|Rep: TRNA pseudouridylate synthase -
Ostreococcus tauri
Length = 450
Score = 39.9 bits (89), Expect = 0.056
Identities = 23/65 (35%), Positives = 36/65 (55%), Gaps = 8/65 (12%)
Query: 158 EFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQN--CPSDGLYL 215
E G++F+ +QIR+++GT+++V G L DD K + H F+ P GL+L
Sbjct: 230 EVVGQSFMLHQIRKLIGTMLAVMRGTLDEDDQKFAILS------HQFVPTPMAPELGLFL 283
Query: 216 CEVEY 220
CE Y
Sbjct: 284 CECIY 288
>UniRef50_Q4D3D3 Cluster: Putative uncharacterized protein; n=3;
Trypanosoma|Rep: Putative uncharacterized protein -
Trypanosoma cruzi
Length = 634
Score = 39.9 bits (89), Expect = 0.056
Identities = 20/64 (31%), Positives = 37/64 (57%), Gaps = 3/64 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
IE HG++F+ NQIR+M+G +IS+ L P ++ L + + P++GL+L
Sbjct: 500 IELHGQSFMLNQIRKMIGAVISICAAGLSPQYLRDHL---LNKAVRCGVPMAPANGLFLS 556
Query: 217 EVEY 220
+++
Sbjct: 557 YLDF 560
>UniRef50_Q8X025 Cluster: Related to pseudouridine synthase 3; n=2;
Neurospora crassa|Rep: Related to pseudouridine synthase
3 - Neurospora crassa
Length = 669
Score = 39.9 bits (89), Expect = 0.056
Identities = 34/114 (29%), Positives = 48/114 (42%), Gaps = 11/114 (9%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFD--KLLQHKHNR---------RELKSVTIRAGKPVV 141
DI+ ++ AK EG HDF F K D K + + R ++L+S G P
Sbjct: 345 DIDMMRKAAKMFEGVHDFRNFCKIDPGKQITNFSRRVFESDIVEVKDLESDLPYLGLPEF 404
Query: 142 TAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
S G + G AF+ +QIR MV L V G P V+ +L +
Sbjct: 405 QPPAGSDGPHPKVYYFHVRGSAFLWHQIRHMVAVLFLVGQGLEPPSIVQQLLDV 458
>UniRef50_O87016 Cluster: tRNA pseudouridine synthase A; n=132;
Proteobacteria|Rep: tRNA pseudouridine synthase A -
Pseudomonas aeruginosa
Length = 285
Score = 39.9 bits (89), Expect = 0.056
Identities = 34/128 (26%), Positives = 58/128 (45%), Gaps = 19/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
DI + +E A+ L G HDF++F ++V +A PV T H
Sbjct: 153 DIGRMREAAQVLVGTHDFTSF----------------RAVQCQAKSPVKTMHHVRLLEHG 196
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
++ G AF+H+ +R + G L+++ G+ + K +L+ + + + P G
Sbjct: 197 RLIVLDIRGNAFLHHMVRNIAGVLMTIGAGERPIEWAKEVLEARDRRA--GGVTAHPY-G 253
Query: 213 LYLCEVEY 220
LYL VEY
Sbjct: 254 LYLVRVEY 261
>UniRef50_Q7U335 Cluster: tRNA pseudouridine synthase A; n=7;
Gammaproteobacteria|Rep: tRNA pseudouridine synthase A -
Haemophilus ducreyi
Length = 261
Score = 39.9 bits (89), Expect = 0.056
Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 19/128 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D +K + ++L G DFS+F+ K H R +R G V+
Sbjct: 135 DAQKMHQAGQYLLGEQDFSSFRA-AKCQSHTPWRNIHHLNVVRQGNYVI----------- 182
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
++ AFVH+ +R +VG+L+ V G+ + +K +L+ ++ ++G
Sbjct: 183 ----VDIQANAFVHHMVRNIVGSLLEVGQGRQPIEWIKWLLEQKNR---QLAAPTTKAEG 235
Query: 213 LYLCEVEY 220
LYL VEY
Sbjct: 236 LYLVNVEY 243
>UniRef50_Q6ANM1 Cluster: tRNA pseudouridine synthase A 1; n=1;
Desulfotalea psychrophila|Rep: tRNA pseudouridine
synthase A 1 - Desulfotalea psychrophila
Length = 251
Score = 39.9 bits (89), Expect = 0.056
Identities = 40/149 (26%), Positives = 65/149 (43%), Gaps = 19/149 (12%)
Query: 75 VIPVEEWKRCHFIRLAE-FDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVT 133
VIP + KR + + + D E ++ + + G HDFS+F+ + T
Sbjct: 119 VIPPQ--KRLYMLHQEKPIDQEAMQKCLQIIIGTHDFSSFENTGS-----------RDKT 165
Query: 134 IRAGKPVVTAHTESRGSAF--DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKV 191
GK V E+R F D W F G F+ N +R +VG+++ V GK + V+
Sbjct: 166 RTGGKGAVRTILEARYEQFEEDSWHFVFIGDGFLRNMVRNIVGSILEVGRGK---ESVEW 222
Query: 192 MLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
Q + ++ P+ GL L +V Y
Sbjct: 223 FEQALKEKDRNAAGPTAPAHGLKLFQVFY 251
>UniRef50_Q4SEJ2 Cluster: Pseudouridylate synthase; n=3;
Tetraodontidae|Rep: Pseudouridylate synthase - Tetraodon
nigroviridis (Green puffer)
Length = 412
Score = 39.5 bits (88), Expect = 0.074
Identities = 30/115 (26%), Positives = 51/115 (44%), Gaps = 5/115 (4%)
Query: 83 RCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVT 142
R +F R ++E + A+ EG HDF K D R + S ++ PV
Sbjct: 210 RYYFPR-GSLNVELMADAAERYEGTHDFRNLCKMDVGNGVLQFERTILSSSVT---PVNP 265
Query: 143 AHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPS 197
H S +D + E G AF+++Q+R M+ L+ + P+ + +L + S
Sbjct: 266 EHASSTDQ-YDIFVFEVRGLAFLYHQVRCMMALLLLIGQKLEAPEIINQLLDVQS 319
>UniRef50_Q11XU3 Cluster: Pseudouridylate synthase; n=1; Cytophaga
hutchinsonii ATCC 33406|Rep: Pseudouridylate synthase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 248
Score = 39.5 bits (88), Expect = 0.074
Identities = 27/81 (33%), Positives = 45/81 (55%), Gaps = 13/81 (16%)
Query: 154 YWD-----IEFHGRA--FVHNQIRRMVGTLISVAIGKLQPDD-VKVMLQIPSKHSWHSFI 205
YW+ + FH +A F+ +R +VGT++ V G++ DD V+++L K + S
Sbjct: 170 YWERNGDMLYFHVKANRFLRGMVRTLVGTMLEVGKGRMSLDDFVQIILAKDRKRAGIS-- 227
Query: 206 QNCPSDGLYLCEVEYDPKDLF 226
P + LYL EVEY P +++
Sbjct: 228 --APPEALYLSEVEY-PAEVY 245
>UniRef50_A4CM73 Cluster: Pseudouridylate synthase; n=1;
Robiginitalea biformata HTCC2501|Rep: Pseudouridylate
synthase - Robiginitalea biformata HTCC2501
Length = 253
Score = 39.5 bits (88), Expect = 0.074
Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 4/72 (5%)
Query: 155 WDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLY 214
W F+ N +R +VGTL+ V G+L + VK + I S+ + + + P+ GLY
Sbjct: 179 WVFTISADRFLRNMVRAVVGTLLEVGKGRLDAEGVKTI--IKSQDRSEAGV-SVPAKGLY 235
Query: 215 LCEVEYDPKDLF 226
L + Y P LF
Sbjct: 236 LTRITY-PDTLF 246
>UniRef50_A1AXN3 Cluster: Pseudouridylate synthase; n=3;
Bacteria|Rep: Pseudouridylate synthase - Ruthia
magnifica subsp. Calyptogena magnifica
Length = 247
Score = 39.5 bits (88), Expect = 0.074
Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 3/112 (2%)
Query: 109 DFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQ 168
D K K L KHN + +A + T D ++ AF+H+
Sbjct: 136 DIMAMNKASKYLIGKHNFSAFRGSLCQAKSSIKTIEFIKLNKCDDNILLDIKADAFLHHM 195
Query: 169 IRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
+R +VGTL+ V G+ + VK +L + PS GLY + Y
Sbjct: 196 VRNIVGTLLKVGKGEKSIEWVKEILDNKQR---KQAAPAAPSHGLYFIKAFY 244
>UniRef50_Q9PP96 Cluster: tRNA pseudouridine synthase A; n=13;
Campylobacter|Rep: tRNA pseudouridine synthase A -
Campylobacter jejuni
Length = 241
Score = 39.5 bits (88), Expect = 0.074
Identities = 35/123 (28%), Positives = 57/123 (46%), Gaps = 8/123 (6%)
Query: 101 AKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIE-F 159
A ++ Y F K ++LL +++LK G T A+ Y D F
Sbjct: 124 ASYVHFYPKFD-LGKANELLGFFVGKKDLKFFCKSGGDNKTTLREIFIARAYAYKDFSIF 182
Query: 160 HGRA--FVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCE 217
H +A F+ QIR V +++ V GK+ ++K QI +K ++ F+ P +GLYL
Sbjct: 183 HFKANGFLRGQIRLSVASVLKVLEGKMSEKELKE--QIEAKKQYNHFL--APPNGLYLSR 238
Query: 218 VEY 220
+ Y
Sbjct: 239 ICY 241
>UniRef50_Q89ZY4 Cluster: tRNA pseudouridine synthase A; n=3;
Bacteroides|Rep: tRNA pseudouridine synthase A -
Bacteroides thetaiotaomicron
Length = 269
Score = 39.5 bits (88), Expect = 0.074
Identities = 34/134 (25%), Positives = 59/134 (44%), Gaps = 17/134 (12%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D E+ E A+ L Y DF++F K H + + ++ T+ G
Sbjct: 134 DYERMNEAARTLFEYIDFTSFSKL-----HTDVKTNICHISH-------AEWTKMEGEDT 181
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
W F+ N +R +VGTL+ V GKL + + +++ + + + P +
Sbjct: 182 T-WVFTIRADRFLRNMVRAIVGTLLEVGRGKLTVEGFRKVIEQQDRCKAGT---SAPGNA 237
Query: 213 LYLCEVEYDPKDLF 226
L+L VEY P+D+F
Sbjct: 238 LFLVNVEY-PEDIF 250
>UniRef50_Q64XV0 Cluster: tRNA pseudouridine synthase A; n=16;
Bacteroidetes|Rep: tRNA pseudouridine synthase A -
Bacteroides fragilis
Length = 252
Score = 39.5 bits (88), Expect = 0.074
Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 19/134 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D +K E A L Y DF++F K H + + + H E
Sbjct: 137 DFQKMNEAALTLFHYSDFTSFSKL-----HTDVKTNICKIM----------HAEWTQEDE 181
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
W F+ N +R +VGTL+ V GKL D + +++ ++ + + P +
Sbjct: 182 YTWVFTIQADRFLRNMVRAIVGTLLEVGRGKLSVVDFRKIIEQQNRCKAGT---SAPGNA 238
Query: 213 LYLCEVEYDPKDLF 226
L+L VEY P+++F
Sbjct: 239 LFLVNVEY-PQEIF 251
>UniRef50_A7RII9 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 300
Score = 39.1 bits (87), Expect = 0.098
Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 14/104 (13%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
+I K K + YH+F++ KKF+ +++ ++ + GKP E G F
Sbjct: 138 EINKALSNYKGTKNYHNFTSGKKFEDPSANRY------IISFKCGKPF-----ERNGREF 186
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIP 196
++ G++FV +QIR+M+G +I+V G + P ++ IP
Sbjct: 187 VVLTVK--GQSFVLHQIRKMIGLVIAVVRG-VAPSSTFDLIDIP 227
>UniRef50_Q9X1R0 Cluster: tRNA pseudouridine synthase A; n=5;
Thermotogaceae|Rep: tRNA pseudouridine synthase A -
Thermotoga maritima
Length = 245
Score = 39.1 bits (87), Expect = 0.098
Identities = 30/128 (23%), Positives = 57/128 (44%), Gaps = 19/128 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
E D++ ++ K+LEG HDF++FK + R + +R +V E
Sbjct: 135 ELDLDAMRKAVKYLEGTHDFTSFKTGSD--ERDPVRTIYRIRILRLKNDLVLIRVE---- 188
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
GR+F+ +R +V L+ V + + +P+ +K +L+ + + P+
Sbjct: 189 ----------GRSFLRRMVRNIVAALVKVGLKQWEPEKMKEVLEARDR---SAAAGTAPA 235
Query: 211 DGLYLCEV 218
GLY +V
Sbjct: 236 HGLYFYKV 243
>UniRef50_Q72DL8 Cluster: tRNA pseudouridine synthase A; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: tRNA
pseudouridine synthase A - Desulfovibrio vulgaris
(strain Hildenborough / ATCC 29579 / NCIMB8303)
Length = 297
Score = 39.1 bits (87), Expect = 0.098
Identities = 43/160 (26%), Positives = 62/160 (38%), Gaps = 30/160 (18%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKK----FDKLLQHKHNRRELKSVTIRAG----------- 137
D+ A+HL G HDF+ F+ ++ H R S T+ AG
Sbjct: 141 DVYAMDRAARHLAGTHDFAAFQNQGTDVTSTVRTVHAIRRCPSGTLPAGALLTCSEPYTS 200
Query: 138 ---------KPVVTAHTESRGSAFDY-WDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPD 187
+P TA G + W F G F+ +R M+G L++V G L D
Sbjct: 201 WRCTGTHPDQPPATAGHPLAGIGLELVWS--FEGDGFLKQMVRNMMGLLVAVGRGALAAD 258
Query: 188 DVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYDPKDLFY 227
DV ++ + + P+ GL L EV Y P D Y
Sbjct: 259 DVPGIMATLDRSRAPA---TAPACGLTLSEVYYPPCDYPY 295
>UniRef50_Q6MDE3 Cluster: tRNA pseudouridine synthase A 2; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep: tRNA
pseudouridine synthase A 2 - Protochlamydia amoebophila
(strain UWE25)
Length = 262
Score = 39.1 bits (87), Expect = 0.098
Identities = 34/125 (27%), Positives = 53/125 (42%), Gaps = 16/125 (12%)
Query: 96 KFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYW 155
K + L G HDFS F F K + + R ++++ + V H
Sbjct: 154 KMTQAISVLIGEHDFSAFCNFKKNVNYTDYIRRVQAIHLE-----VLNHKRLC------- 201
Query: 156 DIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYL 215
I G F++ +R +VGTLI + GKL +D+ +LQ + P+ GL+L
Sbjct: 202 -IRIKGNHFLYKMVRNIVGTLIYIGKGKLMVEDIPSILQSQDRKMAG---VTAPAHGLFL 257
Query: 216 CEVEY 220
V Y
Sbjct: 258 QTVLY 262
>UniRef50_Q59S63 Cluster: tRNA pseudouridine synthase 1; n=2;
Saccharomycetales|Rep: tRNA pseudouridine synthase 1 -
Candida albicans (Yeast)
Length = 450
Score = 39.1 bits (87), Expect = 0.098
Identities = 38/160 (23%), Positives = 69/160 (43%), Gaps = 18/160 (11%)
Query: 72 IANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKS 131
I + +E R + R++ ++ F+E K EG H+F F NR +K+
Sbjct: 202 IKQIKTIENQSRRSY-RISSSRLQHFREVMKQYEGTHNFHNFTVGKPFKDTSANRFMIKT 260
Query: 132 VTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVG-----TLISVAIGKLQP 186
+ P V TE + I+ HG++F+ +QIR+M+ +S+ G +
Sbjct: 261 I---VSDPFVIEGTE-------WISIKIHGQSFMLHQIRKMIAMAALVVRLSLPCGIINN 310
Query: 187 DDVKVMLQIPSKHSWHSFIQNCPSDG--LYLCEVEYDPKD 224
+ IP + ++N DG + L + +Y+P D
Sbjct: 311 FFQSTKINIPKAPALGLLLENPVFDGYNIKLTKSDYEPID 350
>UniRef50_A4EA88 Cluster: Pseudouridylate synthase; n=1; Collinsella
aerofaciens ATCC 25986|Rep: Pseudouridylate synthase -
Collinsella aerofaciens ATCC 25986
Length = 274
Score = 38.7 bits (86), Expect = 0.13
Identities = 19/73 (26%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
D G AF+H+ +R +VGTL+ + + + +P+ ++ ++ + + P+ G
Sbjct: 201 DILTFTIEGNAFLHSMVRTIVGTLVEIGMHRRKPEWMREVIDACDRTAAG---PTAPACG 257
Query: 213 LYLCEVEYDPKDL 225
L V+YDP +L
Sbjct: 258 LTFMGVDYDPAEL 270
>UniRef50_A5K9J6 Cluster: tRNA pseudouridine synthase, putative;
n=1; Plasmodium vivax|Rep: tRNA pseudouridine synthase,
putative - Plasmodium vivax
Length = 545
Score = 38.7 bits (86), Expect = 0.13
Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 15/131 (11%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+EK KE K G H F F+ K + K V + H + R + +
Sbjct: 416 DVEKIKECCKLFLGRHSFELFRGTLK------GTEKQKQVNPFCNISFLELH-QLRSNIY 468
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNC-PSD 211
+ G F+++ IR +VGTL+ V +G L +DV+ L ++ C P+
Sbjct: 469 QF---VIQGDRFLYHMIRIIVGTLVQVGVGLLSYEDVRDALHFSKPLK----VKLCAPAQ 521
Query: 212 GLYLCEVEYDP 222
GL L ++ + P
Sbjct: 522 GLCLTKILFPP 532
>UniRef50_UPI0000DB7775 Cluster: PREDICTED: similar to CG3045-PA;
n=2; Endopterygota|Rep: PREDICTED: similar to CG3045-PA
- Apis mellifera
Length = 406
Score = 38.3 bits (85), Expect = 0.17
Identities = 35/159 (22%), Positives = 71/159 (44%), Gaps = 12/159 (7%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
+F +I+ + K++ G HDF K D + R++ + +R +
Sbjct: 185 YFFPRGNLNIDAMNKAVKYIIGEHDFRNICKMDVANGVINYIRKVINAEVRMYRQ----- 239
Query: 145 TESRG-SAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPS--KHSW 201
+ R S +D + + +AF+ +QIR ++G L + GK + + + +L I + K
Sbjct: 240 -DFRNISGYDMYQLIITSQAFLWHQIRCLMGVLFLIGEGKEEAEIMLELLDIENCPKKPQ 298
Query: 202 HSFIQNCPSDGLYLCEVEYDPKDLFYDPDTTVESETLVE 240
++ P + L+ C EYD K+ + D + L++
Sbjct: 299 YNLAHEIPLN-LWYC--EYDAKEWYIHKDELFNTIKLLQ 334
>UniRef50_Q4UA31 Cluster: TRNA-pseudouridine synthase I, putative;
n=1; Theileria annulata|Rep: TRNA-pseudouridine synthase
I, putative - Theileria annulata
Length = 480
Score = 38.3 bits (85), Expect = 0.17
Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 16/134 (11%)
Query: 90 AEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHT-ESR 148
A F EK KE A+ G H+F F+K + N R+ + P+ T H+ E
Sbjct: 338 APFSFEKLKEAARVFHGKHNFEAFRK-----NCRGNERD------KIIDPICTIHSIEFV 386
Query: 149 GSAFD-YWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQN 207
D +I +G F++ +R +V LI ++PD +K L ++ I
Sbjct: 387 NIPQDKKVEIIVNGDRFLYKMVRCIVSHLILAGFNVIKPDQIKRALDNATE---IPNIPY 443
Query: 208 CPSDGLYLCEVEYD 221
P+ GLYL +V ++
Sbjct: 444 APAHGLYLKKVFFE 457
>UniRef50_A6R922 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 555
Score = 38.3 bits (85), Expect = 0.17
Identities = 39/130 (30%), Positives = 55/130 (42%), Gaps = 24/130 (18%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIR----AGKPV-------- 140
DIE ++GAK+L G HDF F K D Q ++ R + I KP+
Sbjct: 273 DIEAMRKGAKYLIGSHDFRNFCKVDPSKQITNHVRHIYHADIELLDPKTKPLSYLRQHEF 332
Query: 141 VTAHTE-----SRGSAFD------YWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDV 189
T TE + GS D + I HG AF+ +Q+R + L V G P +
Sbjct: 333 TTFDTENDKAAANGSIGDPSSNLKVYSITIHGSAFLWHQVRHLAAILFLVGQGLEAPSII 392
Query: 190 KVMLQIPSKH 199
+L + KH
Sbjct: 393 PELLDV-EKH 401
>UniRef50_Q8TU65 Cluster: tRNA pseudouridine synthase A; n=5;
Archaea|Rep: tRNA pseudouridine synthase A -
Methanosarcina acetivorans
Length = 269
Score = 38.3 bits (85), Expect = 0.17
Identities = 36/150 (24%), Positives = 63/150 (42%), Gaps = 21/150 (14%)
Query: 85 HFIRLAE-FDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTA 143
H++ E +DI K +E +K L G HDF F + + K R L+ + +R +
Sbjct: 112 HYVMSGEDYDISKMREASKLLLGTHDFENFSRSN---GEKSTVRTLERINVRVDGEIT-- 166
Query: 144 HTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHS 203
I+ G +F+ N +R++V L + G D +LQ+ + +
Sbjct: 167 ------------KIDVVGNSFLWNMVRKIVTALSMIGNGVRDND---WLLQMLNPEIYEE 211
Query: 204 FIQNCPSDGLYLCEVEYDPKDLFYDPDTTV 233
I+ P GL L V Y + + D ++
Sbjct: 212 GIEPAPPYGLTLMGVNYGENIEWIEDDYSI 241
>UniRef50_Q8CXS6 Cluster: tRNA pseudouridine synthase A; n=3;
Leptospira|Rep: tRNA pseudouridine synthase A -
Leptospira interrogans
Length = 207
Score = 38.3 bits (85), Expect = 0.17
Identities = 40/154 (25%), Positives = 60/154 (38%), Gaps = 18/154 (11%)
Query: 77 PVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRA 136
P WK F D+ + + + L+G HDF + K L T+R
Sbjct: 62 PRPTWKNRTFWYQHRIDVPRLEAELELLKGEHDFRSLAKVASLKGRS---------TVRT 112
Query: 137 GKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIP 196
++ E ++ F+HN IR + GTL+ ++ GK + D V+ +
Sbjct: 113 ---ILDVKLERSLELEGLLKVKIRANGFLHNMIRILTGTLLEISNGKRK--DTNVLEILS 167
Query: 197 SKHSWHSFIQNCPSDGLYLCEVEYD--PK-DLFY 227
SK + I P GLY YD PK D Y
Sbjct: 168 SKDRTIAGI-TLPPYGLYFIRAYYDSYPKIDFMY 200
>UniRef50_Q09524 Cluster: Probable tRNA pseudouridine synthase
tag-124; n=2; Caenorhabditis|Rep: Probable tRNA
pseudouridine synthase tag-124 - Caenorhabditis elegans
Length = 402
Score = 38.3 bits (85), Expect = 0.17
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 6/107 (5%)
Query: 90 AEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGK-PVVTAHTESR 148
A+ ++EK ++GA+ L G HDFS F + D + +R L+S + + V T
Sbjct: 174 ADLNLEKMRQGAELLVGEHDFSNFCQID-----MNEKRLLQSYVRKVYEVKVEQVSTHPE 228
Query: 149 GSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
+ ++ G F+ + IR +V L + QP + +L +
Sbjct: 229 NDMYSMVELTVSGSGFLWHMIRYIVTILQEIGRENEQPSLISQLLDL 275
>UniRef50_UPI00015BE519 Cluster: UPI00015BE519 related cluster; n=1;
unknown|Rep: UPI00015BE519 UniRef100 entry - unknown
Length = 247
Score = 37.9 bits (84), Expect = 0.23
Identities = 36/128 (28%), Positives = 59/128 (46%), Gaps = 22/128 (17%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+ K E + GY DF + F K L+ ++ ++++T + P+V
Sbjct: 142 DLGKMMEISHLFLGYKDF---RGFTKELEDENGYCSVENITFKVDYPLV----------- 187
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+I F+ +RRMVGT++S A G + DDV L+ + S H+ + G
Sbjct: 188 ---EISITANRFLRYMVRRMVGTMLSYAQGLISIDDVNDFLK-AKRVSNHT----AKAHG 239
Query: 213 LYLCEVEY 220
LYL +V Y
Sbjct: 240 LYLKKVYY 247
>UniRef50_Q1IRQ4 Cluster: Pseudouridylate synthase; n=2;
Acidobacteria|Rep: Pseudouridylate synthase -
Acidobacteria bacterium (strain Ellin345)
Length = 257
Score = 37.9 bits (84), Expect = 0.23
Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 7/117 (5%)
Query: 104 LEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRA 163
++G HDF++F D + E + + + A + G + E G
Sbjct: 148 IQGEHDFTSFAASDPDRAQRIRDAEDEDGPSNV-RTIYDAVWRTEGHELIF---EVRGNG 203
Query: 164 FVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
F+H+ +R +VGT + GK Q + M +I + S + P+ GLYL VEY
Sbjct: 204 FLHHMVRNLVGTFVD--FGKWQ-HPAESMAKILREKSRSAAGPAAPASGLYLVNVEY 257
>UniRef50_Q6NKP7 Cluster: Pseudouridylate synthase; n=8;
Magnoliophyta|Rep: Pseudouridylate synthase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 372
Score = 37.9 bits (84), Expect = 0.23
Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 5/113 (4%)
Query: 111 STFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDY--WDIEFHGRAFVHNQ 168
S D L + E VT G+ + +S G + + + R F+++Q
Sbjct: 261 SNLNNGDPLACSNQPKSETAGVTTNVGEVEGSTGGDSFGRRRRHRCYVVTARSRGFLYHQ 320
Query: 169 IRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYD 221
+R +VG L V G+L DV+ +L+ + + P+ GLYL V Y+
Sbjct: 321 VRLIVGALKCVGTGELTVSDVERILEAKTVSAAKPM---APASGLYLARVRYE 370
>UniRef50_Q8I3U5 Cluster: Putative uncharacterized protein PFE0815w;
n=1; Plasmodium falciparum 3D7|Rep: Putative
uncharacterized protein PFE0815w - Plasmodium falciparum
(isolate 3D7)
Length = 681
Score = 37.9 bits (84), Expect = 0.23
Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
DI K KE AK G+H+F F+ K +L+ + + + E + + +
Sbjct: 552 DINKIKECAKLFIGHHNFECFRGTLK------GTEKLRKINTFCTIHFLDVY-ELKNNLY 604
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
+ G F+++ IR +VGTL+ V +G L +DV+ L +
Sbjct: 605 QF---VIQGDRFLYHMIRIIVGTLVQVGVGLLNVEDVRDALHL 644
>UniRef50_Q6C194 Cluster: Pseudouridylate synthase; n=1; Yarrowia
lipolytica|Rep: Pseudouridylate synthase - Yarrowia
lipolytica (Candida lipolytica)
Length = 443
Score = 37.9 bits (84), Expect = 0.23
Identities = 32/115 (27%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
+F + DI+ ++ AK G HD+ F K D Q H+ R + + A
Sbjct: 217 YFFHKGDLDIDLMRQAAKLYLGEHDYRNFCKVDGSKQLAHHNRVM-----------LEAE 265
Query: 145 TESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKH 199
E Y++++ GRAF+ +Q+R M+ L V KL+ V L P K+
Sbjct: 266 IEQLSDDIYYFNLK--GRAFLWHQVRCMMAILFLVG-QKLEKPSVITDLLNPEKY 317
>UniRef50_A5E2I9 Cluster: Pseudouridylate synthase; n=4;
Saccharomycetales|Rep: Pseudouridylate synthase -
Lodderomyces elongisporus (Yeast) (Saccharomyces
elongisporus)
Length = 491
Score = 37.9 bits (84), Expect = 0.23
Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 12/129 (9%)
Query: 67 PENVSIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNR 126
PEN A E R F + + DI+ + A++ EG HDF F K D Q
Sbjct: 244 PENFD-ARFSCKERHYRYLFRKTSTLDIDLMAQAAEYYEGLHDFRNFCKLDGSKQLTSFV 302
Query: 127 RELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQP 186
R+ IR K + +S G+ + + + G AF+ +Q+R MV L V P
Sbjct: 303 RD-----IRRSKII---PLDSDGNLYCF---DLIGNAFLWHQVRCMVAILFLVGQKLESP 351
Query: 187 DDVKVMLQI 195
+ VK ++ +
Sbjct: 352 EIVKDLMDV 360
>UniRef50_Q8D2P5 Cluster: tRNA pseudouridine synthase A; n=1;
Wigglesworthia glossinidia endosymbiont of Glossina
brevipalpis|Rep: tRNA pseudouridine synthase A -
Wigglesworthia glossinidia brevipalpis
Length = 264
Score = 37.9 bits (84), Expect = 0.23
Identities = 43/164 (26%), Positives = 75/164 (45%), Gaps = 25/164 (15%)
Query: 58 AVLKKDV-VIPENVSIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKF 116
A+ KK + +I N+S + + K C + ++ +I K+ A+ L G HDFS+FK
Sbjct: 105 AIAKKYLYLIHNNISRSGIFR----KYCFNVFIS-LNINDMKKAAQKLIGKHDFSSFKGS 159
Query: 117 DKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTL 176
+ Q K R + + I K +Y +E +F+++ +R ++G L
Sbjct: 160 E--CQSKTTYRVIYYIRINKYK--------------EYIFVEIKANSFLNHMMRNIIGNL 203
Query: 177 ISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
I + GK + + +L + K++ S P GLYL V Y
Sbjct: 204 IEIGKGKKSKEWMSELLFL--KNNKFSIFSADPK-GLYLSNVYY 244
>UniRef50_A7C1F2 Cluster: tRNA pseudouridine synthase A; n=1;
Beggiatoa sp. PS|Rep: tRNA pseudouridine synthase A -
Beggiatoa sp. PS
Length = 272
Score = 37.5 bits (83), Expect = 0.30
Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
I+ AF+H+ +R + G LI++ G+ +P +L+ + P+ GLY C
Sbjct: 183 IDISANAFLHHMVRNIAGVLITIGAGEKRPKWADTVLEAQDRTMGGI---TAPAAGLYFC 239
Query: 217 EVEY 220
++Y
Sbjct: 240 GIDY 243
>UniRef50_A6NVS7 Cluster: Pseudouridylate synthase; n=1; Bacteroides
capillosus ATCC 29799|Rep: Pseudouridylate synthase -
Bacteroides capillosus ATCC 29799
Length = 249
Score = 37.5 bits (83), Expect = 0.30
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 3/98 (3%)
Query: 124 HNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGK 183
H+ ++SV V T H + + D + F++N +R MVGT + A GK
Sbjct: 151 HDFAAVQSVGTEVQSTVRTVHYFNMTRSGDMIECRVCANGFLYNMVRAMVGTCVYAAEGK 210
Query: 184 LQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYD 221
P+ V +L+ + + P GLY+ ++ Y+
Sbjct: 211 FPPEAVSDILEGRCRTAAG---PTAPPGGLYMTKLWYE 245
>UniRef50_Q9W282 Cluster: Pseudouridylate synthase; n=2;
Sophophora|Rep: Pseudouridylate synthase - Drosophila
melanogaster (Fruit fly)
Length = 499
Score = 37.5 bits (83), Expect = 0.30
Identities = 29/113 (25%), Positives = 49/113 (43%), Gaps = 5/113 (4%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
++ + DI ++ L + DF F K D + R L+S + A T H
Sbjct: 227 YYFPKGDLDIAAMRKACDLLVRHADFRNFCKMDVHNGVTNYMRNLQSARVEACDQ--TNH 284
Query: 145 TESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPS 197
T S +D + +E AF+ +QIR ++ L+ V K P + +L + S
Sbjct: 285 TNS---GYDMYYLEIQANAFLWHQIRCIMAVLLLVGQKKENPGVISDLLDVES 334
>UniRef50_O84469 Cluster: tRNA pseudouridine synthase A; n=7;
Chlamydiaceae|Rep: tRNA pseudouridine synthase A -
Chlamydia trachomatis
Length = 267
Score = 37.5 bits (83), Expect = 0.30
Identities = 31/132 (23%), Positives = 58/132 (43%), Gaps = 19/132 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
+ +I + +E A++L G HDF++F + ++ R L ++ + + +VT
Sbjct: 138 KLNIARMQEAAQYLVGTHDFASFANLGR--EYSSTIRTLYTLDLSEQEHLVT-------- 187
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
+ G F++ +R +VG L+ + GK P+ + ML + + P
Sbjct: 188 ------VICRGNGFLYKMVRNIVGALLDIGKGKYPPEHLLDMLATKDRRKGP---PSAPP 238
Query: 211 DGLYLCEVEYDP 222
GL L V Y P
Sbjct: 239 YGLSLHHVCYPP 250
>UniRef50_Q1NYR1 Cluster: TRNA pseudouridine synthase A; n=2;
Candidatus Sulcia muelleri str. Hc (Homalodisca
coagulata)|Rep: TRNA pseudouridine synthase A -
Candidatus Sulcia muelleri str. Hc (Homalodisca
coagulata)
Length = 192
Score = 37.1 bits (82), Expect = 0.40
Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 8/73 (10%)
Query: 154 YWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGL 213
Y++IE ++ N +R +VGTLI + IGK+ D +L ++ I + P+ GL
Sbjct: 126 YFNIE--ANRYLRNMVRSIVGTLIELGIGKITIKDFINILYAKDRN-----IISAPAKGL 178
Query: 214 YLCEVEYDPKDLF 226
+L ++ Y P ++F
Sbjct: 179 FLTKINY-PLNIF 190
>UniRef50_Q0U5E9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 621
Score = 37.1 bits (82), Expect = 0.40
Identities = 27/82 (32%), Positives = 46/82 (56%), Gaps = 14/82 (17%)
Query: 107 YHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVH 166
YH+++ KKF K +R +KS + A KP++ TE + ++ HG++F+
Sbjct: 425 YHNYTVQKKFSD----KSAQRYIKSFKV-APKPIIINDTE-------WLSLKVHGQSFMM 472
Query: 167 NQIRRMVGTL-ISVAIGKLQPD 187
+QIR+MVG + ++V G PD
Sbjct: 473 HQIRKMVGMVALTVRCGS-NPD 493
>UniRef50_A2SU30 Cluster: Pseudouridylate synthase; n=1;
Methanocorpusculum labreanum Z|Rep: Pseudouridylate
synthase - Methanocorpusculum labreanum (strain ATCC
43576 / DSM 4855 / Z)
Length = 281
Score = 37.1 bits (82), Expect = 0.40
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 29/133 (21%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+ + ++ A L G H+FS F K + AG+ V T +R F
Sbjct: 119 DVSRMQDAASRLIGTHNFSGFAKME------------------AGRDPV--RTVTRAEVF 158
Query: 153 DYWD----IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNC 208
+ D E ++F+ N +R M G L ++ +G +PD ++ +L P+ +
Sbjct: 159 EGKDGCPVFEVAAKSFLWNMVRGMAGALQTIGLGLCEPDVIEELLSSPTAR-----VHPA 213
Query: 209 PSDGLYLCEVEYD 221
P++GL +V D
Sbjct: 214 PAEGLVFWDVVCD 226
>UniRef50_Q1FEL6 Cluster: Pseudouridylate synthase; n=1; Clostridium
phytofermentans ISDg|Rep: Pseudouridylate synthase -
Clostridium phytofermentans ISDg
Length = 264
Score = 36.7 bits (81), Expect = 0.53
Identities = 37/131 (28%), Positives = 58/131 (44%), Gaps = 14/131 (10%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
+ DIE ++ AK L G D+ +F K K R + +TI + + +G
Sbjct: 145 DLDIEAMRQAAKLLIGTMDYKSFCTDRK--DGKSTIRTISEITIEE----LRQNRNQQGI 198
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPS 210
F F G F+H+ IR + GTL+ V + + V+ I K ++ I P
Sbjct: 199 IFT-----FRGNGFLHHMIRIISGTLLEVGTQERSVESVR--QAILGKKREYAGITLYP- 250
Query: 211 DGLYLCEVEYD 221
GL+L +V YD
Sbjct: 251 QGLFLKQVIYD 261
>UniRef50_A7ANC8 Cluster: Putative uncharacterized protein; n=1;
Babesia bovis|Rep: Putative uncharacterized protein -
Babesia bovis
Length = 778
Score = 36.7 bits (81), Expect = 0.53
Identities = 28/128 (21%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Query: 7 KDTATKKSSEKIWLKENRNLPDPESVQGMMELSLLKLRSLNYPNVTLSSRLAVLKKDVVI 66
KD +S+++ ++EN+ P G+ +L+ + + +L + +++S LA+ + + +
Sbjct: 593 KDLFQVGNSDRLPMEENKT---PCLDYGIFKLNTMGISTLRF-RYSMNSLLAICRSPMSL 648
Query: 67 PENVSIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFD-KLLQHKHN 125
++ ++P+EE + C IE K+ L + + + KL H N
Sbjct: 649 HISLIAERIVPIEEKESCFITVFPNEKIETLKDVLSSLFKINQRWQLEDAEKKLFAHLGN 708
Query: 126 RRELKSVT 133
R+ L+S+T
Sbjct: 709 RQALESIT 716
>UniRef50_P47428 Cluster: tRNA pseudouridine synthase A; n=3;
Mycoplasma|Rep: tRNA pseudouridine synthase A -
Mycoplasma genitalium
Length = 244
Score = 36.7 bits (81), Expect = 0.53
Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
+ F G F+ +Q+R +V L+++ K+ + V + + P K S + PS GLYL
Sbjct: 182 LTFFGSGFLRSQVRMIVACLVNLNTNKMALETVAKLFEHPKK---GSCVVKAPSCGLYLK 238
Query: 217 EVEYD 221
V Y+
Sbjct: 239 TVVYE 243
>UniRef50_Q9BZE2 Cluster: tRNA pseudouridine synthase 3; n=19;
Euteleostomi|Rep: tRNA pseudouridine synthase 3 - Homo
sapiens (Human)
Length = 481
Score = 36.7 bits (81), Expect = 0.53
Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 4/112 (3%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
+F A+ DI A+ G HDF K D + +R + S ++ V +
Sbjct: 197 YFFPRADLDIVTMDYAAQKYVGTHDFRNLCKMDVANGVINFQRTILSAQVQL---VGQSP 253
Query: 145 TESRGSA-FDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
E R F E G+AF+++Q+R M+ L + G +P+ + +L I
Sbjct: 254 GEGRWQEPFQLCQFEVTGQAFLYHQVRCMMAILFLIGQGMEKPEIIDELLNI 305
>UniRef50_Q6CC39 Cluster: tRNA pseudouridine synthase 1; n=1;
Yarrowia lipolytica|Rep: tRNA pseudouridine synthase 1 -
Yarrowia lipolytica (Candida lipolytica)
Length = 528
Score = 36.7 bits (81), Expect = 0.53
Identities = 40/151 (26%), Positives = 72/151 (47%), Gaps = 15/151 (9%)
Query: 71 SIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELK 130
++ + VE R F R++ + K +E K EG H+F F K + R +K
Sbjct: 286 TLEKIKAVERRHREEF-RISGERLAKIREILKIYEGTHNFHNFT-LGKAFKDPSAMRTMK 343
Query: 131 SVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVK 190
S+T P + TE + I+ HG++F+ +QIR+M+ +++++++ + D K
Sbjct: 344 SLT--CSDPFLIDGTE-------WVSIKIHGQSFMLHQIRKMI-SMVALSV-RCNADPQK 392
Query: 191 VMLQIPSKHSWHSFIQNCPSDGLYLCEVEYD 221
++ Q K + I P+ GL L YD
Sbjct: 393 LIPQTFEKARIN--IPKAPALGLLLERPVYD 421
>UniRef50_Q2S4S9 Cluster: Pseudouridylate synthase; n=1;
Salinibacter ruber DSM 13855|Rep: Pseudouridylate
synthase - Salinibacter ruber (strain DSM 13855)
Length = 265
Score = 36.3 bits (80), Expect = 0.69
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 155 WDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLY 214
W +E G F+H +R +VGTL+ + K D + +L + + + P +GL
Sbjct: 182 WRVEVVGTRFLHGMVRALVGTLVEIGHEKRAADALPAVLAARDRRAAG---PSMPPEGLV 238
Query: 215 LCEVEYDPKDLFYD 228
L V Y+ + LF D
Sbjct: 239 LEAVRYE-QPLFDD 251
>UniRef50_A2E6F9 Cluster: tRNA pseudouridine synthase family
protein; n=1; Trichomonas vaginalis G3|Rep: tRNA
pseudouridine synthase family protein - Trichomonas
vaginalis G3
Length = 346
Score = 36.3 bits (80), Expect = 0.69
Identities = 19/61 (31%), Positives = 35/61 (57%), Gaps = 5/61 (8%)
Query: 161 GRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
G +F+ NQIR+M+ + + + ++ P++V L + IQ P DGL+L ++EY
Sbjct: 227 GISFMLNQIRKMISMVTAASFNQVTPEEVSRSLTEETCR-----IQLLPGDGLFLDQIEY 281
Query: 221 D 221
+
Sbjct: 282 E 282
>UniRef50_A4R2D6 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 694
Score = 36.3 bits (80), Expect = 0.69
Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 11/114 (9%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTI----RAGKPVVTAHT-ES 147
D++ +E A+ EG HDF F K D Q + +R ++ +I A + T +
Sbjct: 386 DLDAMREAARLFEGEHDFRNFCKIDASKQISNFKRLIREASIVEVPEAASSLPYLDTPDF 445
Query: 148 RGSAFD------YWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
R S D + G AF+ +QIR M+ L V +P V +L I
Sbjct: 446 RPSGEDSQARPKVYYFHVRGSAFLWHQIRHMIAVLFLVGQRLEKPSIVSELLDI 499
>UniRef50_Q6MEE7 Cluster: tRNA pseudouridine synthase A 1; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep: tRNA
pseudouridine synthase A 1 - Protochlamydia amoebophila
(strain UWE25)
Length = 256
Score = 36.3 bits (80), Expect = 0.69
Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
+EF G F++ +R +VGTL+ VA K +++ QI + + P +GL+L
Sbjct: 188 LEFEGDGFLYKMVRNIVGTLMDVASHKRAIEEIN---QIFAAKNRRQASLAAPPEGLFLI 244
Query: 217 EVEYD 221
+V Y+
Sbjct: 245 QVFYE 249
>UniRef50_A4XKB7 Cluster: Pseudouridylate synthase; n=3;
Clostridiales|Rep: Pseudouridylate synthase -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 244
Score = 35.9 bits (79), Expect = 0.92
Identities = 18/57 (31%), Positives = 34/57 (59%), Gaps = 3/57 (5%)
Query: 164 FVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
F++N R + GT++ V +G+ +P D+ ++++ SK + + P GLYL +V Y
Sbjct: 191 FLYNMARIIAGTILDVGVGRFKPTDIPLIIE--SKDRTKAG-KTLPPWGLYLVDVVY 244
>UniRef50_Q4WYK4 Cluster: Pseudouridylate synthase 3; n=6;
Eurotiomycetidae|Rep: Pseudouridylate synthase 3 -
Aspergillus fumigatus (Sartorya fumigata)
Length = 610
Score = 35.9 bits (79), Expect = 0.92
Identities = 34/132 (25%), Positives = 50/132 (37%), Gaps = 23/132 (17%)
Query: 87 IRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPV------ 140
+R DI+ +E A++ EG HDF F K D Q ++ R + I P
Sbjct: 312 LREGWLDIDAMREAARYFEGVHDFRNFCKLDTSKQIENFERIIYHADIELLDPKDHPLGY 371
Query: 141 -----------VTAHTESRGSAF------DYWDIEFHGRAFVHNQIRRMVGTLISVAIGK 183
A T + F + HG AF+ +Q+R MV L V G
Sbjct: 372 VNQPGFQALQDAPARTSAESGTFTSPAAAKVYVFNLHGSAFLWHQVRHMVSILFLVGQGL 431
Query: 184 LQPDDVKVMLQI 195
P V+ +L +
Sbjct: 432 EPPTIVRDLLDV 443
>UniRef50_Q6AD25 Cluster: tRNA pseudouridine synthase A; n=4;
Actinobacteria (class)|Rep: tRNA pseudouridine synthase
A - Leifsonia xyli subsp. xyli
Length = 288
Score = 35.9 bits (79), Expect = 0.92
Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 3/58 (5%)
Query: 163 AFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
AF H+ +R +VG + V GKL+P D ++ + + S + P+ GL L EV Y
Sbjct: 215 AFCHSMVRALVGACVEVGEGKLRPGD---LVTLRDERQRTSAFKVMPARGLTLREVGY 269
>UniRef50_Q5PAN6 Cluster: tRNA pseudouridine synthase A; n=12;
Alphaproteobacteria|Rep: tRNA pseudouridine synthase A -
Anaplasma marginale (strain St. Maries)
Length = 247
Score = 35.9 bits (79), Expect = 0.92
Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
+ ++F+H Q+R +VGTL+ G P V L+I + + + P GLYL
Sbjct: 187 VHVSAKSFLHKQVRIIVGTLVQCGHGAFPPSYV---LEILERKNRAAAGITAPPHGLYLV 243
Query: 217 EVEY 220
VEY
Sbjct: 244 LVEY 247
>UniRef50_A5USG0 Cluster: Pseudouridylate synthase; n=3;
Chloroflexaceae|Rep: Pseudouridylate synthase -
Roseiflexus sp. RS-1
Length = 270
Score = 35.5 bits (78), Expect = 1.2
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
I+ AF+ + +R +VGTLI V G++ D +L + + P+ GLYL
Sbjct: 187 IDIAANAFLRHMVRNLVGTLIQVGEGRIDADRFAAVLAGDDRRA----RVLAPAHGLYLM 242
Query: 217 EVEYDPKD 224
V Y P+D
Sbjct: 243 AVRY-PED 249
>UniRef50_Q75M65 Cluster: Pseudouridylate synthase; n=2; Oryza
sativa|Rep: Pseudouridylate synthase - Oryza sativa
subsp. japonica (Rice)
Length = 411
Score = 35.5 bits (78), Expect = 1.2
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 9/105 (8%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
+ +I + ++ A G HD+ F K D + RR + I A + R +
Sbjct: 200 DLNISEMQKAALKFIGEHDYRNFCKMDAANVSNY-RRHITDFNISA--------YDQRSN 250
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
+ W I G AF+ +Q+R MV L + G P V +L I
Sbjct: 251 YDELWAITIKGSAFLWHQVRCMVAVLFLIGQGLETPCIVDSLLDI 295
>UniRef50_Q4P5K5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 913
Score = 35.5 bits (78), Expect = 1.2
Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 16/108 (14%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
DI ++ A+ L G HDF K D Q + RR + V+I V++H S+
Sbjct: 336 DIALMRDAARRLLGEHDFRNLCKIDASKQITNYRRRIDGVSIDR----VSSHWPSKNDGV 391
Query: 153 DYWD-----------IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDV 189
+ D + G AF+++Q+R ++ L V +L+P V
Sbjct: 392 EDDDGGEEGEEHMYVLNLRGTAFLYHQVRNIMAILFLVG-ARLEPPSV 438
>UniRef50_Q4P397 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 615
Score = 35.5 bits (78), Expect = 1.2
Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 10/92 (10%)
Query: 88 RLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTES 147
RL + K + G H+F F K + + +R +K +TI K +
Sbjct: 316 RLTPAHLAKIRSIFNRFLGSHNFYNFT-VGKEFRDRSCQRFMKKLTISEPKMI------- 367
Query: 148 RGSAFDYWDIEFHGRAFVHNQIRRMVGTLISV 179
++ I+FHG++F+ +QIR+M+G L+ +
Sbjct: 368 --QGVEWLSIKFHGQSFMLHQIRKMIGLLVLI 397
>UniRef50_UPI0000D554D8 Cluster: PREDICTED: similar to CG4159-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG4159-PA - Tribolium castaneum
Length = 588
Score = 35.1 bits (77), Expect = 1.6
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
I+ G++F+ +QIR+MVG LI+V G D + + + + I P GL L
Sbjct: 449 IKIRGQSFMLHQIRKMVGLLIAVVKGYTSEDTLDLAFGMDKVN-----IPKAPGLGLLLD 503
Query: 217 EVEYDPKDLFYDPD 230
V Y+ D Y D
Sbjct: 504 YVHYERYDNRYGAD 517
>UniRef50_Q47LM3 Cluster: Pseudouridylate synthase; n=2;
Actinomycetales|Rep: Pseudouridylate synthase -
Thermobifida fusca (strain YX)
Length = 296
Score = 35.1 bits (77), Expect = 1.6
Identities = 37/132 (28%), Positives = 57/132 (43%), Gaps = 20/132 (15%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+++ E A L G HDF+ + + +RE S T+R E R +
Sbjct: 164 DVDRMNEAAAALLGEHDFAAYCR----------KREGAS-TVRE-----LQRLEWRRESE 207
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
+ AF HN +R +VG L++V G+ P+ +L+ + S + P G
Sbjct: 208 HVYAATVQADAFCHNMVRALVGALLAVGDGRRPPEWPAQVLRAGVR---DSAVHVVPPHG 264
Query: 213 LYLCEVEYDPKD 224
L L EV Y P D
Sbjct: 265 LTLEEVRY-PAD 275
>UniRef50_Q00RV7 Cluster: TRUA1_PARUW tRNA pseudouridine synthase A
1; n=2; Ostreococcus|Rep: TRUA1_PARUW tRNA pseudouridine
synthase A 1 - Ostreococcus tauri
Length = 705
Score = 35.1 bits (77), Expect = 1.6
Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
+E G F++ Q+R MVG + VA G+ +P+ + L + + P+ GL+L
Sbjct: 213 LECEGDGFLYRQVRNMVGAALVVASGREKPEWI---LDLLASGDRRRVPTAAPARGLFLQ 269
Query: 217 EVEY 220
VEY
Sbjct: 270 SVEY 273
>UniRef50_Q5CPW7 Cluster: Pus1p-like type II pseudousynthas TruA;
n=2; Cryptosporidium|Rep: Pus1p-like type II
pseudousynthas TruA - Cryptosporidium parvum Iowa II
Length = 501
Score = 35.1 bits (77), Expect = 1.6
Identities = 33/133 (24%), Positives = 59/133 (44%), Gaps = 12/133 (9%)
Query: 89 LAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESR 148
L++ D+++F+ G H F F + + R ++ + K V + E +
Sbjct: 325 LSDEDLKRFQSILNEYIGTHSFHNFTSKSSY-EDSTSWRHIEEI-----KVVKVSQNEIK 378
Query: 149 GSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNC 208
G + I G++F+ +QIR+MV I + G + +++ +P K S H
Sbjct: 379 GE-INLIKIIIKGQSFLLHQIRKMVALAIEIFRGTAPSNGIQLCF-LPDKFSIHL----A 432
Query: 209 PSDGLYLCEVEYD 221
PS GL L V Y+
Sbjct: 433 PSQGLLLDRVFYN 445
>UniRef50_Q54TQ3 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 504
Score = 35.1 bits (77), Expect = 1.6
Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 8/74 (10%)
Query: 161 GRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
G +F+ QIRRMVG +S+ G + +++ L+ P + + P LYL V++
Sbjct: 337 GESFILYQIRRMVGFFLSIVKGYSTVEALELSLKSP----FSICVPTAPPFPLYLFNVKF 392
Query: 221 DP----KDLFYDPD 230
DP + LF +P+
Sbjct: 393 DPNSNVEKLFSNPE 406
>UniRef50_Q22BB0 Cluster: TRNA pseudouridine synthase family
protein; n=1; Tetrahymena thermophila SB210|Rep: TRNA
pseudouridine synthase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 35.1 bits (77), Expect = 1.6
Identities = 34/140 (24%), Positives = 56/140 (40%), Gaps = 12/140 (8%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKL-LQHKHNRRELKSVTIRAGKPVVTAHTESRG 149
+ DI++ K+ + G H+F F + Q +EL S I T +
Sbjct: 138 QIDIDRLKQAFQKYLGRHNFYLFTSPEPFQTQFDLFEKELNSFEI-------THYPNEHF 190
Query: 150 SAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQ----IPSKHSWHSFI 205
I G+ F+ Q+R MVG + A K+ + + +L IP +
Sbjct: 191 PKIQSIRISVKGKGFLKYQVRYMVGIAVLYAQKKIDENYLNYLLNPTGFIPQDERRNLIR 250
Query: 206 QNCPSDGLYLCEVEYDPKDL 225
+GL+L +V+YD K L
Sbjct: 251 LKAKPEGLFLYDVQYDQKFL 270
>UniRef50_A6TQL8 Cluster: Pseudouridylate synthase; n=1;
Alkaliphilus metalliredigens QYMF|Rep: Pseudouridylate
synthase - Alkaliphilus metalliredigens QYMF
Length = 248
Score = 34.7 bits (76), Expect = 2.1
Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 17/98 (17%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAF 152
D+ K K+ K+L G HDF F NR+ KS+ V+ E+R
Sbjct: 141 DVTKIKKAGKYLVGEHDFLAFTT---------NRKTTKSIKTMVSLDVM----ETRNEII 187
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVK 190
I F+ N R +VGTLI + +G+L + ++
Sbjct: 188 ----ITMTANGFLLNMERVIVGTLIQIGLGQLPMNTIE 221
>UniRef50_Q6BV13 Cluster: Similar to CA2663|CaNUP133 Candida
albicans; n=1; Debaryomyces hansenii|Rep: Similar to
CA2663|CaNUP133 Candida albicans - Debaryomyces hansenii
(Yeast) (Torulaspora hansenii)
Length = 1173
Score = 34.7 bits (76), Expect = 2.1
Identities = 35/114 (30%), Positives = 52/114 (45%), Gaps = 11/114 (9%)
Query: 30 ESVQGMMELSLLKLRSLNYPNVTLSSRLAVLKKDVVIPENVSIANVIPVEEWKRCHFIRL 89
ESVQ L L+ + L + L+S + V + ENV A ++ WKRC I L
Sbjct: 146 ESVQHAPALGLINNKLLEL-TIPLNSSKG---EYVTLAENVEPAGIVIATSWKRCVLISL 201
Query: 90 AEFDIE---KFKE--GAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGK 138
+F + + E G H G S F F K H N ++ + V+I++GK
Sbjct: 202 RDFKSKPQLSYIELLGPSHSGGLLS-SIFNGFSKNDDHNGNVKD-EIVSIKSGK 253
>UniRef50_UPI00015B411C Cluster: PREDICTED: similar to
pseudouridylate synthase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to pseudouridylate synthase - Nasonia
vitripennis
Length = 437
Score = 34.3 bits (75), Expect = 2.8
Identities = 40/149 (26%), Positives = 65/149 (43%), Gaps = 14/149 (9%)
Query: 82 KRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVV 141
K H RL + EK E K LEG H+F F L + R + + A +P +
Sbjct: 224 KPFHEYRLPQERKEKLTELLKVLEGTHNFHNFTSKVLPLDPRAKRYIMSFI---AEEPFL 280
Query: 142 TAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSW 201
+ E + ++ G++F+ +QIR+MV +I V + ++ + + +K+
Sbjct: 281 VNNME-------FITLKVKGQSFMLHQIRKMVAMVIGVIRNIVPREEFEKTVFEQAKYD- 332
Query: 202 HSFIQNCPSDGLYLCEVEYDPKDLFYDPD 230
I PS GL L V YD + Y D
Sbjct: 333 ---ITIAPSLGLMLNIVHYDYYNKRYGSD 358
>UniRef50_UPI0000E87E98 Cluster: tRNA pseudouridine synthase A; n=1;
Methylophilales bacterium HTCC2181|Rep: tRNA
pseudouridine synthase A - Methylophilales bacterium
HTCC2181
Length = 264
Score = 34.3 bits (75), Expect = 2.8
Identities = 27/106 (25%), Positives = 44/106 (41%), Gaps = 3/106 (2%)
Query: 118 KLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLI 177
K + H+ +S +A PV T + + + F+H+QIR M+ +I
Sbjct: 144 KCFEGTHDFSSFRSSECQAKSPVRTINQFRCEQFGNTYLFTIRANGFLHHQIRNMIAAVI 203
Query: 178 SVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEYDPK 223
VA + D V + + SK +GLYL ++YD K
Sbjct: 204 HVAKNE---DSVGFIDDLLSKKDRTLAPPTFMPNGLYLSNIKYDDK 246
>UniRef50_UPI00006CC0EE Cluster: tRNA pseudouridine synthase family
protein; n=1; Tetrahymena thermophila SB210|Rep: tRNA
pseudouridine synthase family protein - Tetrahymena
thermophila SB210
Length = 309
Score = 34.3 bits (75), Expect = 2.8
Identities = 36/138 (26%), Positives = 56/138 (40%), Gaps = 12/138 (8%)
Query: 93 DIEKFKEGAKHLEGYHDFSTFK-KFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSA 151
D EK + + G H+F F K + + R + S+TI ++
Sbjct: 166 DQEKLNQALQQYVGTHNFQNFTIKAEHISHFGCYVRTIDSITIEN-------YSHPFYEE 218
Query: 152 FDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQN---- 207
I F ++F+ QIR MVG + A+GKL D +L P + + +N
Sbjct: 219 AQCIKIIFKAKSFLAYQIRFMVGEALQYALGKLDFDSFLKLLDPPKELTPQEVHENNRIR 278
Query: 208 CPSDGLYLCEVEYDPKDL 225
GL L V+Y P+ L
Sbjct: 279 AQPRGLMLKRVDYPPEML 296
>UniRef50_UPI000018F668 Cluster: similar to DNA helicase; n=1;
Rhodothermus phage RM378|Rep: similar to DNA helicase -
Bacteriophage RM 378
Length = 670
Score = 34.3 bits (75), Expect = 2.8
Identities = 25/82 (30%), Positives = 41/82 (50%), Gaps = 7/82 (8%)
Query: 101 AKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFH 160
A L+GY D ++++ LL+ K+++ EL SVT + V A T +DY+ +
Sbjct: 59 ASKLKGYFDEKAAQQYNLLLEEKNHKLELSSVT--SSDFAVPAPT-----GYDYFPFQKA 111
Query: 161 GRAFVHNQIRRMVGTLISVAIG 182
G FV + G LI+ +G
Sbjct: 112 GVHFVTEVFKEYPGALIADEMG 133
>UniRef50_Q0LPW8 Cluster: Pseudouridylate synthase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Pseudouridylate synthase - Herpetosiphon aurantiacus
ATCC 23779
Length = 272
Score = 34.3 bits (75), Expect = 2.8
Identities = 19/66 (28%), Positives = 31/66 (46%), Gaps = 3/66 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
+ AF+ + +R +VGTL+ V G+L ++ I + + P GLYL
Sbjct: 188 LHLQANAFLKHMVRNIVGTLLMVGDGRL---SLEAWQAIIASRDRRNAGPTAPPQGLYLE 244
Query: 217 EVEYDP 222
+ YDP
Sbjct: 245 SIGYDP 250
>UniRef50_A0Z5L5 Cluster: TRNA pseudouridine synthase A; n=1; marine
gamma proteobacterium HTCC2080|Rep: TRNA pseudouridine
synthase A - marine gamma proteobacterium HTCC2080
Length = 226
Score = 34.3 bits (75), Expect = 2.8
Identities = 22/103 (21%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
Query: 118 KLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLI 177
++L +H+ ++ +A PV S D+ ++ AF+++ +R +VG+L
Sbjct: 107 QILLGEHDFSAFRAAQCQAAHPVRQIFGVSVNRVGDFVILDIEANAFLYHMVRNLVGSLQ 166
Query: 178 SVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
V G+ P+ ++ +L+ + + GLYL + Y
Sbjct: 167 MVGSGQRPPEWIEQLLEGKDRTLGG---DTASASGLYLQSITY 206
>UniRef50_Q4Q3H7 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 701
Score = 34.3 bits (75), Expect = 2.8
Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
IE G++F+ NQIR+M+G ++ +A L ++ +L + I P++GL+L
Sbjct: 566 IELDGQSFMLNQIRKMIGAVVCIAAAGLPGSYIRDVL---LRKGVRRGIPMAPANGLFLS 622
Query: 217 EVEY 220
+++
Sbjct: 623 YLDF 626
>UniRef50_A1C4K8 Cluster: FAD binding domain protein; n=1;
Aspergillus clavatus|Rep: FAD binding domain protein -
Aspergillus clavatus
Length = 580
Score = 34.3 bits (75), Expect = 2.8
Identities = 20/75 (26%), Positives = 31/75 (41%)
Query: 139 PVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSK 198
P+ + H + S W F F+ VG+L+ A+ P+DV+ LQ
Sbjct: 93 PLPSVHYSTPSSPMAAWFANFSCDPFLGPDSTCTVGSLVQYAVNVTDPEDVRQTLQFTRT 152
Query: 199 HSWHSFIQNCPSDGL 213
H+ I+N D L
Sbjct: 153 HNIRLVIRNTGHDYL 167
>UniRef50_UPI00015B40A8 Cluster: PREDICTED: similar to
pseudouridylate synthase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to pseudouridylate synthase - Nasonia
vitripennis
Length = 421
Score = 33.9 bits (74), Expect = 3.7
Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 85 HFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAH 144
+F +IE + AK G HDF K D + R + + A +
Sbjct: 195 YFFPRGNLNIEAMDKAAKLTVGSHDFRNLCKMDVANGVVNFFRNI----VNAQVTCIKRE 250
Query: 145 TESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQI 195
+ S +D ++ AF+ +QIR ++G L+ V + +P+ + +L +
Sbjct: 251 DPEKISGYDMCELSIKSNAFLWHQIRCIMGILLLVGREQEKPEVITDLLDV 301
>UniRef50_UPI0000DAE4B2 Cluster: hypothetical protein
Rgryl_01000436; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000436 - Rickettsiella
grylli
Length = 2238
Score = 33.9 bits (74), Expect = 3.7
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 4/109 (3%)
Query: 17 KIWLKENRNLPDPESVQGMMELSLLKLRSLN---YPNVTLSSRLAVLKKDVVIPENVSIA 73
K++ ++ N P P VQ ++ + L L+ YP++ +S + + D+V + +
Sbjct: 139 KLYYIDSLNYPLPPEVQTFLQTESILLNDLSHTLYPHIN-NSNVGLWVLDIVENIHKMLD 197
Query: 74 NVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQH 122
N I +E+ K ++D FKE K+L ST K D +H
Sbjct: 198 NEISLEDMKIIFSYLPQQYDSHYFKEKRKNLAQKISESTEKVADAWPEH 246
>UniRef50_Q8GB97 Cluster: Pseudouridylate synthase; n=2;
Clostridiales|Rep: Pseudouridylate synthase -
Heliobacillus mobilis
Length = 249
Score = 33.9 bits (74), Expect = 3.7
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 161 GRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
G F++N +R + GTL+ V GK+ P+ + QI + P GL L EV
Sbjct: 185 GDGFLYNMVRIITGTLVDVGKGKIAPESIP---QIIASRDRTQAGTTAPPQGLALLEVWI 241
Query: 221 DPKDLF 226
LF
Sbjct: 242 SSGRLF 247
>UniRef50_A7HCM5 Cluster: tRNA-pseudouridine synthase I; n=2;
Anaeromyxobacter|Rep: tRNA-pseudouridine synthase I -
Anaeromyxobacter sp. Fw109-5
Length = 265
Score = 33.9 bits (74), Expect = 3.7
Identities = 34/131 (25%), Positives = 55/131 (41%), Gaps = 19/131 (14%)
Query: 90 AEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRG 149
A D+ H G HDF+ F + + R +++VT RA VV+A
Sbjct: 141 ARLDVAAMSAALAHAVGTHDFTAFARPGE------QRGTVRTVT-RA--EVVSATWAPLH 191
Query: 150 SAFDYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCP 209
+ + F G F+ IR + GT ++V +G+ P+ V+ +L ++ P
Sbjct: 192 A------LVFEGHGFLRAMIRNLAGTAVTVGVGRAAPEIVRELLLARGRYRG----VRAP 241
Query: 210 SDGLYLCEVEY 220
GL L V Y
Sbjct: 242 GWGLTLASVVY 252
>UniRef50_A7ASP1 Cluster: tRNA pseudouridine synthase, putative;
n=1; Babesia bovis|Rep: tRNA pseudouridine synthase,
putative - Babesia bovis
Length = 414
Score = 33.9 bits (74), Expect = 3.7
Identities = 32/128 (25%), Positives = 57/128 (44%), Gaps = 17/128 (13%)
Query: 106 GYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFV 165
G HDF F + K+ + K +R + + + +ES G + + G++F+
Sbjct: 233 GSHDFKNFTQRQKV-EEKTTQRFIHEIKVEG--------SESIG--INAVRVIITGQSFL 281
Query: 166 HNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSF-IQNCPSDGLYLCEVEYDPKD 224
+NQIR+M+G +V +G +K L WH+ P++GL+L +D +
Sbjct: 282 YNQIRKMIGLGYAVYLGVAPRCAIKFALS-----KWHAVNTPLAPAEGLFLHHPYFDAYN 336
Query: 225 LFYDPDTT 232
P T
Sbjct: 337 RRCSPPQT 344
>UniRef50_Q73KE3 Cluster: tRNA pseudouridine synthase A; n=1;
Treponema denticola|Rep: tRNA pseudouridine synthase A -
Treponema denticola
Length = 268
Score = 33.9 bits (74), Expect = 3.7
Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 4/80 (5%)
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
DY E AF+ +R +VGTL+ + D K +L+ + P G
Sbjct: 192 DYLIFEICANAFLWKMVRSIVGTLLHLDEIGASKKDFKDILESKMREKAG---PTAPPQG 248
Query: 213 LYLCEVEYDPKDLFYDPDTT 232
L+L +EY P+DL P T
Sbjct: 249 LFLWSIEY-PEDLLKAPPET 267
>UniRef50_O94295 Cluster: tRNA pseudouridine synthase 2; n=1;
Schizosaccharomyces pombe|Rep: tRNA pseudouridine
synthase 2 - Schizosaccharomyces pombe (Fission yeast)
Length = 451
Score = 33.9 bits (74), Expect = 3.7
Identities = 29/116 (25%), Positives = 51/116 (43%), Gaps = 10/116 (8%)
Query: 64 VVIPENVSIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHK 123
+VIP + + E+ R+ E ++ ++ K EG H+F F D
Sbjct: 244 IVIPPQAKLKKALKQAEYYCYMNYRIKEDRLKVLQQLLKKYEGRHNFHNFTVTDDSTSPS 303
Query: 124 HNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQIRRMVGTLISV 179
N R ++SVT G P V + E + + G +F+ NQIR+M+ ++ +
Sbjct: 304 -NYRFIESVT--CGTPFVYENWE-------WIPVTIKGNSFMLNQIRKMMAHVLMI 349
>UniRef50_Q30RV9 Cluster: Pseudouridylate synthase; n=1;
Thiomicrospira denitrificans ATCC 33889|Rep:
Pseudouridylate synthase - Thiomicrospira denitrificans
(strain ATCC 33889 / DSM 1351)
Length = 236
Score = 33.5 bits (73), Expect = 4.9
Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 9/64 (14%)
Query: 157 IEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLC 216
+ F F+ +QIR MVG L+S L D++ L+ H I+ S+GLYL
Sbjct: 182 LNFEANGFLRSQIRLMVGALLS-----LNEDEILDKLECRVNHK----IKPAKSNGLYLS 232
Query: 217 EVEY 220
+++Y
Sbjct: 233 KIKY 236
>UniRef50_Q1FHP1 Cluster: Extracellular solute-binding protein,
family 1 precursor; n=1; Clostridium phytofermentans
ISDg|Rep: Extracellular solute-binding protein, family
1 precursor - Clostridium phytofermentans ISDg
Length = 451
Score = 33.5 bits (73), Expect = 4.9
Identities = 17/40 (42%), Positives = 26/40 (65%)
Query: 14 SSEKIWLKENRNLPDPESVQGMMELSLLKLRSLNYPNVTL 53
SS+KI LK NLPD ++ QG++E ++ + PNVT+
Sbjct: 52 SSDKITLKLFSNLPDRKNGQGLIEQMIIDEYTNKNPNVTI 91
>UniRef50_A3I2E1 Cluster: TRNA pseudouridine synthase A; n=1;
Algoriphagus sp. PR1|Rep: TRNA pseudouridine synthase A
- Algoriphagus sp. PR1
Length = 233
Score = 33.5 bits (73), Expect = 4.9
Identities = 30/133 (22%), Positives = 55/133 (41%), Gaps = 14/133 (10%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
E + E E K G HDF +F K + + +NR L + + E G
Sbjct: 98 ELNWEAMNEACKSFIGKHDFKSFCKPSEN-KTDYNREVLSAE--------ICDSNEFMGQ 148
Query: 151 AFDY--WDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNC 208
F + + + G F+H+Q+R M+ L + G++ +++ + + +
Sbjct: 149 YFPHKIYYFQITGTGFLHHQVRMMMSALWQIGKGEMDLSEIEARFESSDR---FEKLPPA 205
Query: 209 PSDGLYLCEVEYD 221
P++GL L E D
Sbjct: 206 PANGLVLWETILD 218
>UniRef50_A0LIV1 Cluster: Pseudouridylate synthase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pseudouridylate
synthase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 261
Score = 33.5 bits (73), Expect = 4.9
Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 3/62 (4%)
Query: 159 FHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEV 218
F F+ + +R +VGT++ V G P++ L I S P+ GL+L V
Sbjct: 195 FEANGFLRHMVRNLVGTIVEVGRGVRAPEE---FLDILSSRDRKRAGMTAPAHGLFLTAV 251
Query: 219 EY 220
Y
Sbjct: 252 HY 253
>UniRef50_A0DFY8 Cluster: Pseudouridylate synthase; n=1; Paramecium
tetraurelia|Rep: Pseudouridylate synthase - Paramecium
tetraurelia
Length = 414
Score = 33.5 bits (73), Expect = 4.9
Identities = 36/151 (23%), Positives = 65/151 (43%), Gaps = 14/151 (9%)
Query: 45 SLNYPNVTLSSRLAVLKKDVVIPENVSIANVIPVEEW--------KRCH--FIRLAEFDI 94
+LN + S +L + V+PE++ I + V+E KR + + +++I
Sbjct: 115 ALNVRKIGKSDKLYAQILNRVLPEDIQILDECIVDEKFNARYDCIKRVYKYYFYKMDYNI 174
Query: 95 EKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFD- 153
E E G HDF F K D ++ +++ R + ++TI P + D
Sbjct: 175 ELMTEAMLLFIGEHDFRNFCKLD-VIANQNFVRTIMNITIEEVFPENAPRCSTLFKDDDR 233
Query: 154 --YWDIEFHGRAFVHNQIRRMVGTLISVAIG 182
+ + G AF+ +QIR M+ L + G
Sbjct: 234 LRLYCVTIEGNAFLWHQIRYMMAVLFLIGKG 264
>UniRef50_A3GG38 Cluster: Nuclear pore complex protein involved in
poly(A)+ RNA transport, nuclear pore distribution, and
possibly in the biogenesis of functional tRNA; n=2;
Pichia stipitis|Rep: Nuclear pore complex protein
involved in poly(A)+ RNA transport, nuclear pore
distribution, and possibly in the biogenesis of
functional tRNA - Pichia stipitis (Yeast)
Length = 1150
Score = 33.5 bits (73), Expect = 4.9
Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 4/63 (6%)
Query: 30 ESVQGMMELSLLKLRSLNYPNVTLSSRLAVLKKDVVIPENVSIANVIPVEEWKRCHFIRL 89
ESVQ L L+ +SL + ++S+ + + + ENV A +I WKRC I L
Sbjct: 152 ESVQHAPALGLINDKSLEL-TIPINSKKG---EYITLAENVEPAGIIVATSWKRCVLISL 207
Query: 90 AEF 92
+F
Sbjct: 208 RDF 210
>UniRef50_Q979R4 Cluster: tRNA pseudouridine synthase A; n=1;
Thermoplasma volcanium|Rep: tRNA pseudouridine synthase
A - Thermoplasma volcanium
Length = 246
Score = 33.5 bits (73), Expect = 4.9
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 18/84 (21%)
Query: 106 GYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFV 165
G+HDFS F K K R +S+ V H ES G +EF ++F+
Sbjct: 127 GFHDFSKFSK-------KDTRNPWRSID------EVKCHRESFGVV-----LEFSAKSFL 168
Query: 166 HNQIRRMVGTLISVAIGKLQPDDV 189
NQ+RRM+ ++ K+ P V
Sbjct: 169 WNQVRRMLAFILEFRGNKIDPFSV 192
>UniRef50_Q9ZCA3 Cluster: tRNA pseudouridine synthase A; n=13;
Rickettsiales|Rep: tRNA pseudouridine synthase A -
Rickettsia prowazekii
Length = 245
Score = 33.5 bits (73), Expect = 4.9
Identities = 24/112 (21%), Positives = 47/112 (41%), Gaps = 3/112 (2%)
Query: 109 DFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHGRAFVHNQ 168
D +K L KH+ +S + ++ P+ T + ++ + +F+H
Sbjct: 137 DILAMQKAAAYLLGKHDFTSFRSSSCQSKSPIKTLTEINIIKEYEEIKLYISAPSFLHYM 196
Query: 169 IRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
+R +VG+L+ V Q + +K +L + P+ GLY + EY
Sbjct: 197 VRNIVGSLVLVGKNIWQAEQIKNVLDARDRKIAG---PTAPAFGLYFIKAEY 245
>UniRef50_UPI00006CB5F6 Cluster: hypothetical protein
TTHERM_00537360; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00537360 - Tetrahymena
thermophila SB210
Length = 1030
Score = 33.1 bits (72), Expect = 6.5
Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 6 DKDTATKKSSEKIWLKENRNLPDPESVQGMMELSLLKLRSLNYPNVTLSSRLAVLKKDVV 65
+K K EK K +NL + ES G +LS ++ S LS ++ +D
Sbjct: 511 EKYNKEKLQWEKNVQKLEKNLREVESAYGK-QLSQVEKDSFKQKEQILSQNQQIIAQDKN 569
Query: 66 IPENVSIANVIPVEEWKRCHFIRLAEFDIEKFKEGAKHLE 105
I E + + + + ++ + ++ E +IEKFK ++H +
Sbjct: 570 ISELIKLKDQLHMQNIELKTTVQNLENEIEKFKNLSRHFQ 609
>UniRef50_A1AY01 Cluster: Putative uncharacterized protein
precursor; n=6; Rhodobacteraceae|Rep: Putative
uncharacterized protein precursor - Paracoccus
denitrificans (strain Pd 1222)
Length = 189
Score = 33.1 bits (72), Expect = 6.5
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 99 EGAKHLEGYHDFSTFKKFD---KLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYW 155
E A EG H+ + KFD + + NR +L +T+ +GKPV TA + + F
Sbjct: 52 EAAGAAEGVHEAGS--KFDFGFSGIMARDNRTQLAPLTLASGKPVATAEYKLKSGGFYRI 109
Query: 156 DIEFHG 161
DI G
Sbjct: 110 DINADG 115
>UniRef50_Q9C5K6 Cluster: Pseudouridylate synthase; n=3; core
eudicotyledons|Rep: Pseudouridylate synthase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 446
Score = 33.1 bits (72), Expect = 6.5
Identities = 28/92 (30%), Positives = 36/92 (39%), Gaps = 9/92 (9%)
Query: 102 KHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFHG 161
K G HDF F K D H + RR VT P +H + F G
Sbjct: 241 KKFIGEHDFRNFCKMDVANVHCYTRR----VTFFEVSPCQNSHEGDQLCTFT-----MRG 291
Query: 162 RAFVHNQIRRMVGTLISVAIGKLQPDDVKVML 193
AF+ +QIR MV L + G D + +L
Sbjct: 292 SAFLWHQIRCMVAVLFMIGQGVESVDVIDTLL 323
>UniRef50_A6SH63 Cluster: Predicted protein; n=1; Botryotinia
fuckeliana B05.10|Rep: Predicted protein - Botryotinia
fuckeliana B05.10
Length = 85
Score = 33.1 bits (72), Expect = 6.5
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 173 VGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFI--QNCPSDGLYLCEVEYDPKDLFYDPD 230
+GT +S +G + ++ +L +P K W I Q SD L CE K D
Sbjct: 11 IGTGLSYTMGAIDDGSLRTILLLPRKRFWEMTIESQQDDSDALAFCEEYKQQKRELVDRM 70
Query: 231 TTVESE 236
T V+ E
Sbjct: 71 TAVDCE 76
>UniRef50_A2TUS1 Cluster: Pseudouridylate synthase; n=2;
Flavobacteriaceae|Rep: Pseudouridylate synthase -
Dokdonia donghaensis MED134
Length = 263
Score = 32.7 bits (71), Expect = 8.6
Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 153 DYWDIEFHGRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDG 212
D + F+ N +R +VGTL+ + GK + +++ S+ S + P G
Sbjct: 188 DEYHFHITANRFLRNMVRAIVGTLLEIGQGKKPVSWIHDVVKGKSRSRAGSSV---PGHG 244
Query: 213 LYLCEVEYDPKDLF 226
LYL E+ Y P+ ++
Sbjct: 245 LYLTEIIY-PETIY 257
>UniRef50_Q23DF3 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 490
Score = 32.7 bits (71), Expect = 8.6
Identities = 32/118 (27%), Positives = 65/118 (55%), Gaps = 13/118 (11%)
Query: 17 KIWLKENRNLPDPESVQGMMELSLLKLRSLNYPNVTLSSRLAVLKKDVVIPENVSIANVI 76
K+ +K +N+ + + + +++ +LLKL++L N+ LSS + L ++ + + +S NV
Sbjct: 164 KLIIKSQKNIMNKQGIS-IIQNTLLKLKNLRSINLYLSSSIDNLNFNLQLSKLIS--NVT 220
Query: 77 PVEEWKRCHFIRLAEFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTI 134
+++ F L +FD +K + +K EG FS FK F +L + R +K++ +
Sbjct: 221 QIKK-----FDLLIDFD-KKNQLASK--EGV--FSIFKSFSQLTNLQSLRFSMKNIYV 268
>UniRef50_A6QYD4 Cluster: Predicted protein; n=2; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 696
Score = 32.7 bits (71), Expect = 8.6
Identities = 17/59 (28%), Positives = 31/59 (52%), Gaps = 5/59 (8%)
Query: 114 KKFDKLLQHKHNRRELKSVTIRA-----GKPVVTAHTESRGSAFDYWDIEFHGRAFVHN 167
K+ +KLL N R++K++ A G+ V H E+ + + +D++FHG + N
Sbjct: 633 KELEKLLNKSSNGRQIKNIARAAFALAKGEVVTITHIETALNCAEEFDLDFHGAGALDN 691
>UniRef50_A3LX03 Cluster: Pseudouridylate synthase; n=4;
Saccharomycetaceae|Rep: Pseudouridylate synthase -
Pichia stipitis (Yeast)
Length = 465
Score = 32.7 bits (71), Expect = 8.6
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 13/89 (14%)
Query: 91 EFDIEKFKEGAKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGS 150
+ DIE E G HDF F K D Q + RE+ S+ I H +
Sbjct: 227 DLDIELMNEACIKYIGSHDFRNFCKIDGSKQITNYVREVYSMKI--------IHLKD--- 275
Query: 151 AFDYWDIEFHGRAFVHNQIRRMVGTLISV 179
D++ ++ G AF+ +Q+R MV L +
Sbjct: 276 --DFYAVDLKGSAFLWHQVRCMVAILFLI 302
>UniRef50_P60349 Cluster: tRNA pseudouridine synthase A; n=13;
Actinomycetales|Rep: tRNA pseudouridine synthase A -
Corynebacterium diphtheriae
Length = 288
Score = 32.7 bits (71), Expect = 8.6
Identities = 45/184 (24%), Positives = 71/184 (38%), Gaps = 17/184 (9%)
Query: 41 LKLRSLNYPNVTLSSRLAVLKKDVVIPENVSIANVIPVEEWKRCHFIRLAEFDIEKFKEG 100
+++ ++++ +R + L++ V +P H+ R DI +
Sbjct: 101 VRIHNMSFVPAEFDARFSALRRHYVYRVTTHPRGALPTRARDTAHWPR--SVDISAMQAA 158
Query: 101 AKHLEGYHDFSTFKKFDKLLQHKHNRRELKSVTIRAGKPVVTAHTESRGSAFDYWDIEFH 160
A L G HDF+ F K+ RE S TIR T H S ++
Sbjct: 159 ADALIGMHDFAAFCKY----------REGAS-TIR-DLQEFTWHDVSTPQEPQLYEAHVT 206
Query: 161 GRAFVHNQIRRMVGTLISVAIGKLQPDDVKVMLQIPSKHSWHSFIQNCPSDGLYLCEVEY 220
AF + +R +VG + V GK + D L +K S S I + GL L V+Y
Sbjct: 207 ADAFCWSMVRSLVGACLVVGEGK-RADGFTEHLLGETKRS--SSIPVAAACGLSLVGVDY 263
Query: 221 DPKD 224
D
Sbjct: 264 PSDD 267
>UniRef50_Q8SQI1 Cluster: Probable DNA-3-methyladenine glycosylase;
n=1; Encephalitozoon cuniculi|Rep: Probable
DNA-3-methyladenine glycosylase - Encephalitozoon
cuniculi
Length = 208
Score = 32.7 bits (71), Expect = 8.6
Identities = 15/33 (45%), Positives = 19/33 (57%)
Query: 2 VTTLDKDTATKKSSEKIWLKENRNLPDPESVQG 34
+T + D SEKIWL+E R + DPE V G
Sbjct: 130 ITRREIDKEWIAGSEKIWLEEGREVADPEIVAG 162
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 271,027,819
Number of Sequences: 1657284
Number of extensions: 10603652
Number of successful extensions: 25469
Number of sequences better than 10.0: 184
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 108
Number of HSP's that attempted gapping in prelim test: 25245
Number of HSP's gapped (non-prelim): 253
length of query: 241
length of database: 575,637,011
effective HSP length: 98
effective length of query: 143
effective length of database: 413,223,179
effective search space: 59090914597
effective search space used: 59090914597
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 71 (32.7 bits)
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