Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002803-TA|BGIBMGA002803-PA|IPR000219|DH
(256 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D570A7 Cluster: PREDICTED: similar to CG3799-PA,... 201 2e-50
UniRef50_Q17LB9 Cluster: Guanine nucleotide exchange factor; n=3... 195 1e-48
UniRef50_Q9Y150 Cluster: CG3799-PA, isoform A; n=3; Neoptera|Rep... 185 8e-46
UniRef50_Q965J0 Cluster: Temporarily assigned gene name protein ... 118 2e-25
UniRef50_UPI00015B5DDA Cluster: PREDICTED: similar to guanine nu... 112 1e-23
UniRef50_UPI000051A1F0 Cluster: PREDICTED: similar to CG3799-PA,... 104 2e-21
UniRef50_Q8N5V2 Cluster: Ephexin-1; n=32; Euteleostomi|Rep: Ephe... 101 1e-20
UniRef50_Q4SC98 Cluster: Chromosome undetermined SCAF14659, whol... 96 9e-19
UniRef50_A7S9L2 Cluster: Predicted protein; n=1; Nematostella ve... 94 4e-18
UniRef50_Q4S825 Cluster: Chromosome 9 SCAF14710, whole genome sh... 91 3e-17
UniRef50_Q5VV41 Cluster: Rho guanine nucleotide exchange factor ... 91 3e-17
UniRef50_O94989 Cluster: Rho guanine nucleotide exchange factor ... 91 3e-17
UniRef50_Q8IW93 Cluster: Rho guanine nucleotide exchange factor ... 90 4e-17
UniRef50_A3QJZ2 Cluster: Novel protein similar to vertebrate Rho... 89 8e-17
UniRef50_Q4TC03 Cluster: Chromosome undetermined SCAF7065, whole... 88 2e-16
UniRef50_A5X5J0 Cluster: Rho guanine nucleotide exchange factor ... 87 3e-16
UniRef50_UPI0000F2BEF5 Cluster: PREDICTED: similar to Rho guanin... 87 4e-16
UniRef50_Q4SME7 Cluster: Chromosome 8 SCAF14552, whole genome sh... 87 5e-16
UniRef50_UPI0000F2E47F Cluster: PREDICTED: similar to zinc finge... 86 9e-16
UniRef50_UPI0000E2181D Cluster: PREDICTED: rho guanine nucleotid... 83 5e-15
UniRef50_UPI0000F210FE Cluster: PREDICTED: hypothetical protein;... 83 9e-15
UniRef50_Q12774 Cluster: Rho guanine nucleotide exchange factor ... 82 1e-14
UniRef50_UPI0000ECD505 Cluster: Rho guanine nucleotide exchange ... 78 2e-13
UniRef50_Q4SPQ5 Cluster: Chromosome 16 SCAF14537, whole genome s... 78 3e-13
UniRef50_Q6Q8Q8 Cluster: SH3-containing guanine nucleotide excha... 77 3e-13
UniRef50_Q5TEV1 Cluster: Rho guanine nucleotide exchange factor ... 74 3e-12
UniRef50_UPI0000F1FF96 Cluster: PREDICTED: hypothetical protein;... 73 5e-12
UniRef50_Q4RXA2 Cluster: Chromosome 11 SCAF14979, whole genome s... 67 5e-10
UniRef50_Q4S6V2 Cluster: Chromosome 14 SCAF14723, whole genome s... 47 4e-04
UniRef50_Q5K7V4 Cluster: Signal transducer, putative; n=2; Filob... 47 5e-04
UniRef50_Q49U75 Cluster: PDZ-RhoGEF; n=2; Danio rerio|Rep: PDZ-R... 43 0.009
UniRef50_A7RTF1 Cluster: Predicted protein; n=8; Eumetazoa|Rep: ... 42 0.012
UniRef50_Q1ZXN6 Cluster: Pleckstrin homology (PH) domain-contain... 42 0.020
UniRef50_Q8WZX1 Cluster: Related to DNA repair endonuclease rad2... 42 0.020
UniRef50_Q0W767 Cluster: Putative uncharacterized protein; n=1; ... 41 0.035
UniRef50_UPI00015B50AC Cluster: PREDICTED: similar to FYVE, RhoG... 40 0.081
UniRef50_UPI000065FF36 Cluster: Homolog of Homo sapiens "pleckst... 40 0.081
UniRef50_UPI0000D5630B Cluster: PREDICTED: similar to CG7323-PA;... 39 0.11
UniRef50_Q9ULL1 Cluster: Pleckstrin homology domain-containing f... 39 0.11
UniRef50_UPI0000DB6D3E Cluster: PREDICTED: similar to RhoGEF2 CG... 39 0.14
UniRef50_Q4P2N2 Cluster: Putative uncharacterized protein; n=1; ... 38 0.19
UniRef50_A7RUA3 Cluster: Predicted protein; n=1; Nematostella ve... 38 0.25
UniRef50_UPI00005887C8 Cluster: PREDICTED: similar to Rho guanin... 38 0.33
UniRef50_UPI000049A230 Cluster: hypothetical protein 13.t00058; ... 38 0.33
UniRef50_A6W4J7 Cluster: Diguanylate cyclase/phosphodiesterase w... 37 0.43
UniRef50_Q8TCU6 Cluster: Phosphatidylinositol 3,4,5-trisphosphat... 37 0.43
UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep: Int... 37 0.43
UniRef50_A7H758 Cluster: 4Fe-4S ferredoxin iron-sulfur binding d... 36 0.76
UniRef50_Q0IPQ9 Cluster: Os12g0174300 protein; n=1; Oryza sativa... 36 0.76
UniRef50_Q54ND2 Cluster: RhoGEF domain-containing protein; n=1; ... 36 0.76
UniRef50_Q54MM3 Cluster: Putative uncharacterized protein; n=1; ... 36 0.76
UniRef50_UPI0000E2546B Cluster: PREDICTED: hypothetical protein;... 36 1.0
UniRef50_Q571N4 Cluster: MKIAA0208 protein; n=1; Mus musculus|Re... 36 1.0
UniRef50_UPI000051ACFC Cluster: PREDICTED: similar to Pleckstrin... 36 1.3
UniRef50_Q4RLN1 Cluster: Chromosome 10 SCAF15019, whole genome s... 36 1.3
UniRef50_Q9XXM9 Cluster: Putative uncharacterized protein uig-1;... 36 1.3
UniRef50_Q54XW8 Cluster: Putative uncharacterized protein; n=1; ... 36 1.3
UniRef50_Q1ZX99 Cluster: RhoGEF domain-containing protein; n=1; ... 36 1.3
UniRef50_Q96UR6 Cluster: GDP/GTP exchange factor Rom2p; n=1; Klu... 36 1.3
UniRef50_Q3UWX6 Cluster: In vitro fertilized eggs cDNA, RIKEN fu... 35 1.8
UniRef50_A0H1D5 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q6WKY8 Cluster: Guanine nucleotide exchange factor; n=2... 35 1.8
UniRef50_Q54DE0 Cluster: Calmodulin-binding protein; n=2; Dictyo... 35 1.8
UniRef50_A0E1W1 Cluster: Chromosome undetermined scaffold_74, wh... 35 1.8
UniRef50_P10911 Cluster: Proto-oncogene DBL (Proto-oncogene MCF-... 35 1.8
UniRef50_UPI000155CE54 Cluster: PREDICTED: similar to ankyrin re... 35 2.3
UniRef50_UPI0000519B3F Cluster: PREDICTED: similar to FYVE, RhoG... 35 2.3
UniRef50_UPI000049976C Cluster: hypothetical protein 115.t00004;... 35 2.3
UniRef50_Q8PP92 Cluster: Putative uncharacterized protein XAC079... 35 2.3
UniRef50_A1WDB2 Cluster: Putative uncharacterized protein precur... 35 2.3
UniRef50_A7SRN5 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.3
UniRef50_A7RXM0 Cluster: Predicted protein; n=1; Nematostella ve... 35 2.3
UniRef50_A4HKE4 Cluster: Putative uncharacterized protein; n=1; ... 35 2.3
UniRef50_A2EKU3 Cluster: Putative uncharacterized protein; n=1; ... 35 2.3
UniRef50_Q504U0 Cluster: LOC201725 protein; n=9; Theria|Rep: LOC... 35 2.3
UniRef50_A4R505 Cluster: Predicted protein; n=1; Magnaporthe gri... 35 2.3
UniRef50_UPI0000F2B1C8 Cluster: PREDICTED: hypothetical protein;... 34 3.1
UniRef50_UPI0000E47DAB Cluster: PREDICTED: similar to epithelial... 34 3.1
UniRef50_UPI000051A437 Cluster: PREDICTED: similar to RhoGEF4 CG... 34 3.1
UniRef50_UPI000065F563 Cluster: Homolog of Brachydanio rerio "Qu... 34 3.1
UniRef50_Q6CSA4 Cluster: Similar to sgd|S0004417 Saccharomyces c... 34 3.1
UniRef50_Q6DEY6 Cluster: MGC89379 protein; n=2; Xenopus|Rep: MGC... 34 4.0
UniRef50_A5NRC7 Cluster: Putative uncharacterized protein; n=1; ... 34 4.0
UniRef50_A0X5W0 Cluster: Putative uncharacterized protein; n=2; ... 34 4.0
UniRef50_A7RLP1 Cluster: Predicted protein; n=1; Nematostella ve... 34 4.0
UniRef50_Q0UHK2 Cluster: Putative uncharacterized protein; n=1; ... 34 4.0
UniRef50_Q96SB4 Cluster: Serine/threonine-protein kinase SRPK1; ... 34 4.0
UniRef50_UPI0000E1E614 Cluster: PREDICTED: similar to novel PH d... 33 5.4
UniRef50_UPI00005A1291 Cluster: PREDICTED: hypothetical protein ... 33 5.4
UniRef50_Q0YHU8 Cluster: Hemerythrin HHE cation binding region; ... 33 5.4
UniRef50_A6NVZ6 Cluster: Single-stranded DNA-binding protein; n=... 33 5.4
UniRef50_A1U9Z9 Cluster: Putative uncharacterized protein; n=6; ... 33 5.4
UniRef50_A1GG63 Cluster: DNA polymerase III, subunits gamma and ... 33 5.4
UniRef50_Q4Q5W0 Cluster: Putative uncharacterized protein; n=3; ... 33 5.4
UniRef50_Q29J41 Cluster: GA15289-PA; n=1; Drosophila pseudoobscu... 33 5.4
UniRef50_A2F8H3 Cluster: Kelch motif family protein; n=1; Tricho... 33 5.4
UniRef50_Q4P9T6 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4
UniRef50_Q70EK9 Cluster: Ubiquitin carboxyl-terminal hydrolase 5... 33 5.4
UniRef50_Q96M96 Cluster: FYVE, RhoGEF and PH domain-containing p... 33 5.4
UniRef50_UPI0000F2E5C5 Cluster: PREDICTED: hypothetical protein;... 33 7.1
UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersecti... 33 7.1
UniRef50_UPI00006C09CB Cluster: PREDICTED: hypothetical protein;... 33 7.1
UniRef50_UPI00015A5797 Cluster: UPI00015A5797 related cluster; n... 33 7.1
UniRef50_Q4SEW8 Cluster: Chromosome undetermined SCAF14611, whol... 33 7.1
UniRef50_Q4SDF0 Cluster: Chromosome 3 SCAF14639, whole genome sh... 33 7.1
UniRef50_Q4G5V0 Cluster: Reticulon 6-a1; n=22; Danio rerio|Rep: ... 33 7.1
UniRef50_Q3J4T6 Cluster: ThiF family protein; n=1; Rhodobacter s... 33 7.1
UniRef50_Q0RGB0 Cluster: ABC-type dipeptide/oligopeptide/nickel ... 33 7.1
UniRef50_A3RV13 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1
UniRef50_Q960G3 Cluster: SD03094p; n=2; Drosophila melanogaster|... 33 7.1
UniRef50_Q6Q427 Cluster: Guanine nucleotide exchange factor; n=4... 33 7.1
UniRef50_A5KAR9 Cluster: Variable surface protein Vir 12, putati... 33 7.1
UniRef50_Q2H9P4 Cluster: Predicted protein; n=1; Chaetomium glob... 33 7.1
UniRef50_P53046 Cluster: RHO1 GDP-GTP exchange protein 1; n=3; S... 33 7.1
UniRef50_Q96NY7 Cluster: Chloride intracellular channel 6; n=111... 33 7.1
UniRef50_Q9NR80 Cluster: Rho guanine nucleotide exchange factor ... 33 7.1
UniRef50_UPI00015B4CDD Cluster: PREDICTED: similar to pleckstrin... 33 9.4
UniRef50_UPI0000F21464 Cluster: PREDICTED: hypothetical protein;... 33 9.4
UniRef50_UPI0000EBEEAA Cluster: PREDICTED: hypothetical protein;... 33 9.4
UniRef50_UPI0000EBC7F9 Cluster: PREDICTED: hypothetical protein;... 33 9.4
UniRef50_UPI00005A02E9 Cluster: PREDICTED: similar to USP6 N-ter... 33 9.4
UniRef50_UPI000049A432 Cluster: Rho guanine nucleotide exchange ... 33 9.4
UniRef50_UPI0000DBF905 Cluster: UPI0000DBF905 related cluster; n... 33 9.4
UniRef50_UPI0000EB3C20 Cluster: UPI0000EB3C20 related cluster; n... 33 9.4
UniRef50_Q4SB75 Cluster: Chromosome undetermined SCAF14677, whol... 33 9.4
UniRef50_Q7UWF8 Cluster: Putative uncharacterized protein; n=1; ... 33 9.4
UniRef50_Q1DAK9 Cluster: Putative uncharacterized protein; n=1; ... 33 9.4
UniRef50_A1VFT2 Cluster: Sensor protein; n=2; Desulfovibrio vulg... 33 9.4
UniRef50_Q25AC2 Cluster: H0522A01.8 protein; n=4; Oryza sativa|R... 33 9.4
UniRef50_Q9UKW0 Cluster: T-cell lymphoma invasion and metastasis... 33 9.4
UniRef50_O94827 Cluster: Pleckstrin homology domain-containing f... 33 9.4
UniRef50_Q6FPQ7 Cluster: Similar to sp|P32521 Saccharomyces cere... 33 9.4
UniRef50_Q5KF15 Cluster: Putative uncharacterized protein; n=2; ... 33 9.4
>UniRef50_UPI0000D570A7 Cluster: PREDICTED: similar to CG3799-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3799-PA, isoform A - Tribolium castaneum
Length = 968
Score = 201 bits (490), Expect = 2e-50
Identities = 108/208 (51%), Positives = 141/208 (67%), Gaps = 9/208 (4%)
Query: 53 EPLYQFYNAAKVESIYRE-TGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGP---- 107
EPLYQFY+AA +ES+ + D DSDGYE V + +RPSAM LV+P
Sbjct: 450 EPLYQFYDAAVLESVCHDGVSDFDSDGYEE-VGDNNSESTLSSRPSAMELVTPNKNLLTV 508
Query: 108 ARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFR 167
+RTLWCE +S+L+ QK+LQEAKFE++TSEASYLNSLNVL + FV +F
Sbjct: 509 SRTLWCEIPEVIQSSV-LSTLSTHQKKLQEAKFEMITSEASYLNSLNVLCNHFVK--SFE 565
Query: 168 DPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYV 227
IL +D+ E+LF + V+ CS+ L+++LEKCWQENILL G+CDIV+ HAEE+F VYV
Sbjct: 566 SLDILSKDELEMLFGKVADVKNCSEKLISDLEKCWQENILLHGVCDIVQKHAEENFHVYV 625
Query: 228 KYCENQTLMVKALQRLRERPAFATALKR 255
YCENQ L+ L+R++ERP F LK+
Sbjct: 626 PYCENQILLDDTLRRIKERPNFLEQLKQ 653
>UniRef50_Q17LB9 Cluster: Guanine nucleotide exchange factor; n=3;
Culicidae|Rep: Guanine nucleotide exchange factor -
Aedes aegypti (Yellowfever mosquito)
Length = 867
Score = 195 bits (475), Expect = 1e-48
Identities = 107/249 (42%), Positives = 142/249 (57%), Gaps = 15/249 (6%)
Query: 9 NKINQLVIMYAEAGLYQXXXXXXXXXXXXXXXXXXXX-------XRSLFTHEPLYQFYNA 61
NK YAEAGLYQ S+F +EPLYQ YNA
Sbjct: 275 NKERSTTSWYAEAGLYQTSDVSVASSSESSGVSTGGEGGGEDDHSHSMFVNEPLYQIYNA 334
Query: 62 AKVESIYRE-----TGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPR-GPARTLWCES 115
AK+ES+ R+ TGD D++ AG + RPSA L+ P G RTLWCE
Sbjct: 335 AKLESLTRDIDAEITGDGDTE-LGAGSGSDEDVVGRKLRPSAFELIEPNVGKLRTLWCEI 393
Query: 116 RRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRD 175
++ L P +KRLQEAKFE+LTSEASYL SLN+L++ F+ HPAFRD +L
Sbjct: 394 PEVINSEILLT-LTPTEKRLQEAKFEILTSEASYLKSLNLLKTHFINHPAFRDVKVLTSS 452
Query: 176 DWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTL 235
+ + LFS I+PV++CS L+ +LE CWQ+NI+L G+ + HAE+HF VYV YCE+Q
Sbjct: 453 ERKTLFSNIIPVQECSDRLLCDLENCWQDNIMLLGLSHSIYKHAEKHFHVYVNYCEHQAK 512
Query: 236 MVKALQRLR 244
+ + L+ L+
Sbjct: 513 IDRTLKNLK 521
>UniRef50_Q9Y150 Cluster: CG3799-PA, isoform A; n=3; Neoptera|Rep:
CG3799-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 1051
Score = 185 bits (451), Expect = 8e-46
Identities = 105/242 (43%), Positives = 139/242 (57%), Gaps = 15/242 (6%)
Query: 18 YAEAGLYQXXXXXXXXXXXXXXXXXXXXX----------RSLFTHEPLYQFYNAAKVESI 67
YAE+GLYQ SLF++EPLYQ Y+AAK+ESI
Sbjct: 468 YAESGLYQTSGISVASSSGSSGVSTGNEAGLGDELSSEPHSLFSNEPLYQMYSAAKLESI 527
Query: 68 YRET-GDSDSDGYEA-GVPGAQAPPP-EPARPSAMALVSPR-GPARTLWCESRRSSTPLC 123
R+ SDGYE G+ P P RP+A+ LV P+ GP+RTLW E C
Sbjct: 528 TRDLEAHGSSDGYEEIGLQAKAKPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHS-C 586
Query: 124 SVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFST 183
+ +L ++ LQEAKFE++TSEASYL SLN+L F+ H AF D +L D + LFS
Sbjct: 587 ILPTLTSRERSLQEAKFEIITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSY 646
Query: 184 ILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRL 243
I+PV +CS+ L+ ELE CWQ+NI+L G+ + AE HF VYV +CE+Q M + L+RL
Sbjct: 647 IVPVHECSERLLTELEACWQDNIMLLGLSRCIYEIAERHFHVYVAFCEHQGRMDRTLRRL 706
Query: 244 RE 245
+E
Sbjct: 707 KE 708
>UniRef50_Q965J0 Cluster: Temporarily assigned gene name protein
218, isoform a; n=3; Caenorhabditis|Rep: Temporarily
assigned gene name protein 218, isoform a -
Caenorhabditis elegans
Length = 1136
Score = 118 bits (283), Expect = 2e-25
Identities = 66/155 (42%), Positives = 91/155 (58%), Gaps = 6/155 (3%)
Query: 106 GPARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPA 165
G R+LWCE + L K QEA FE++TSEASYL SLNVL + F+A P
Sbjct: 631 GSQRSLWCELPEVRAAGL-LEKLDDECKLRQEAYFEVITSEASYLRSLNVLITHFMASPQ 689
Query: 166 FRDPH----ILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEE 221
+L D + LFS I VR CS+ L+ +LE +EN++L ICDI+ H ++
Sbjct: 690 MLGSKSALSVLSDSDRKHLFSNIFAVRDCSERLLCDLETRLEENLILDDICDILSDHFDK 749
Query: 222 HFQVYVKYCENQTLMVKALQRLR-ERPAFATALKR 255
HF+VY+KYC NQ + L+RL+ E P F +A++R
Sbjct: 750 HFEVYIKYCSNQVYQDRTLRRLKTENPGFLSAVQR 784
>UniRef50_UPI00015B5DDA Cluster: PREDICTED: similar to guanine
nucleotide exchange factor; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to guanine
nucleotide exchange factor - Nasonia vitripennis
Length = 1103
Score = 112 bits (269), Expect = 1e-23
Identities = 70/202 (34%), Positives = 109/202 (53%), Gaps = 15/202 (7%)
Query: 48 SLFTHEPLYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGP 107
S+ EPLYQFY + +SDSDGYE E PS+ +
Sbjct: 559 SVLAEEPLYQFYALDATRVAF----ESDSDGYEE---------VEELAPSSATTDLAKPG 605
Query: 108 ARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFR 167
RTLWC++ + + SL+ ++++QEAKFE+LTSEASYLNSL VLE++F ++
Sbjct: 606 HRTLWCQTPQVINSGL-LQSLSTEERKIQEAKFEILTSEASYLNSLRVLENEFASNQELV 664
Query: 168 DPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYV 227
IL + + +F + V S+ + ELE W+++ +L + D++ HA++ QVYV
Sbjct: 665 Q-EILTSAERDKIFGMVPEVLVASERFLAELEGIWRKDPMLLELPDLLLKHADKSCQVYV 723
Query: 228 KYCENQTLMVKALQRLRERPAF 249
YC NQ + +L+ LR + +
Sbjct: 724 DYCSNQVSIDTSLKELRAKKGY 745
>UniRef50_UPI000051A1F0 Cluster: PREDICTED: similar to CG3799-PA,
isoform A isoform 1; n=1; Apis mellifera|Rep: PREDICTED:
similar to CG3799-PA, isoform A isoform 1 - Apis
mellifera
Length = 773
Score = 104 bits (250), Expect = 2e-21
Identities = 72/194 (37%), Positives = 107/194 (55%), Gaps = 16/194 (8%)
Query: 53 EPLYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLW 112
EPLYQFY AA R D +SDGYE V G P+R S L P RTLW
Sbjct: 265 EPLYQFYAAAAA----RIASDFNSDGYEE-VEGII-----PSR-STTDLAKPGH--RTLW 311
Query: 113 CESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHIL 172
C++ + + L +K++QEAKFE+LTSEASYLNSL VL+++F+ + + IL
Sbjct: 312 CQTPQVLNSDL-LKRLTTKEKKIQEAKFEILTSEASYLNSLRVLKTEFLDDSSIDE--IL 368
Query: 173 PRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCEN 232
+ + +F I V + S+ + ELE W+++ +L + +++ +A+ +YV YC N
Sbjct: 369 TSVEKDKIFGDIPSVLQASEQFLAELETVWRQDPMLHDLPNVLLKYADRCLDIYVTYCSN 428
Query: 233 QTLMVKALQRLRER 246
Q + L+ LR R
Sbjct: 429 QVSIDTTLRDLRTR 442
>UniRef50_Q8N5V2 Cluster: Ephexin-1; n=32; Euteleostomi|Rep:
Ephexin-1 - Homo sapiens (Human)
Length = 710
Score = 101 bits (243), Expect = 1e-20
Identities = 67/165 (40%), Positives = 90/165 (54%), Gaps = 8/165 (4%)
Query: 88 APPPEPARPSAMALVSPRGPARTLWCE--SRRSSTPLCSVSSLAPAQKRLQEAKFELLTS 145
A PPE + L+S LW + RSS L L P + +LQEA FEL+TS
Sbjct: 228 ASPPERKTLPQICLLSNPHSRFNLWQDLPEIRSSGVL---EILQPEEIKLQEAMFELVTS 284
Query: 146 EASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQEN 205
EASY SLN+L S F+ + R IL + ILFS +L V S+ + ELE +EN
Sbjct: 285 EASYYKSLNLLVSHFMENERIRK--ILHPSEAHILFSNVLDVLAVSERFLLELEHRMEEN 342
Query: 206 ILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKAL-QRLRERPAF 249
I++ +CDIV +A +HF VY+ Y NQT + Q L+E+ AF
Sbjct: 343 IVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAF 387
>UniRef50_Q4SC98 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14659, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 526
Score = 95.9 bits (228), Expect = 9e-19
Identities = 73/205 (35%), Positives = 104/205 (50%), Gaps = 13/205 (6%)
Query: 55 LYQFYNAAKVE-SIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWC 113
LYQ Y+ + I R+ G + E G G P P PS+ + S RG A LW
Sbjct: 3 LYQEYSDVAINREIQRQQG-KEPGHEEDGSDGT--PSPSNLSPSS-SFRSSRGSAFALWQ 58
Query: 114 E--SRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHI 171
+ RSS L + S+ +++LQEAKFEL+TSEASY+ SL + F+ +
Sbjct: 59 DIPDVRSSGQLDNFSN---EERKLQEAKFELVTSEASYIRSLTIAVDHFMLSQELAE--C 113
Query: 172 LPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCE 231
L D + LFS + V+ S+ + +LE +E+IL +CDIV HH +VY+ Y
Sbjct: 114 LGTQDKQWLFSKLPDVKDVSERFLQDLEHRLEEDILRFDVCDIVLHHCPALRRVYLPYVT 173
Query: 232 NQTLMVKALQR-LRERPAFATALKR 255
NQ + QR L+E P F + L R
Sbjct: 174 NQAYQEQTYQRLLQENPRFHSVLSR 198
>UniRef50_A7S9L2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 469
Score = 93.9 bits (223), Expect = 4e-18
Identities = 46/148 (31%), Positives = 82/148 (55%), Gaps = 4/148 (2%)
Query: 111 LWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDP- 169
LWCE + ++ P +++ QEA FE++TSEASYL SLN+L S F+ P +
Sbjct: 2 LWCELPEVMKSGV-LETIDPTERKRQEAMFEVITSEASYLKSLNILGSHFMDSPELQADT 60
Query: 170 --HILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYV 227
++ + +LF + V + S+ + L + +++ ++ I DI+ HA ++F +Y+
Sbjct: 61 AQSVVEKSQQRVLFGNVKGVLEASEKFLTALRQRQRKSYVISTISDIIEEHATQYFDIYI 120
Query: 228 KYCENQTLMVKALQRLRERPAFATALKR 255
KYC +Q + L+ L + P F A++R
Sbjct: 121 KYCSHQVYQDRILKELGKNPRFVEAVRR 148
>UniRef50_Q4S825 Cluster: Chromosome 9 SCAF14710, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 9
SCAF14710, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 668
Score = 90.6 bits (215), Expect = 3e-17
Identities = 48/132 (36%), Positives = 78/132 (59%), Gaps = 3/132 (2%)
Query: 125 VSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTI 184
++ ++P +++ QEA FE++TSE SYL+SL +L F + A R + + LFS I
Sbjct: 206 LTMISPQERKRQEAIFEIMTSEHSYLHSLGILVRHFHNNGALRKT--MTATEHHHLFSNI 263
Query: 185 LPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQR-L 243
+ + SQ +LE+ EN +++ I DIV++HA HF+ Y+ YC N+T + LQ+ L
Sbjct: 264 AVIHQISQRFFEDLERRHYENPVIRDISDIVQNHASNHFKPYIVYCSNETFQQRTLQKLL 323
Query: 244 RERPAFATALKR 255
AF +LK+
Sbjct: 324 SSNAAFRESLKQ 335
>UniRef50_Q5VV41 Cluster: Rho guanine nucleotide exchange factor 16;
n=24; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 16 - Homo sapiens (Human)
Length = 709
Score = 90.6 bits (215), Expect = 3e-17
Identities = 57/187 (30%), Positives = 93/187 (49%), Gaps = 4/187 (2%)
Query: 69 RETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSL 128
+E G + S + + + P + A +V PA+ W + L + L
Sbjct: 220 QERGLNTSQESDDDILDESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEV-VELGILDQL 278
Query: 129 APAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVR 188
+ +++ QEA FE+LTSE SY +SL++L +F+ R + + + LFS IL V
Sbjct: 279 STEERKRQEAMFEILTSEFSYQHSLSILVEEFLQSKELRAT--VTQMEHHHLFSNILDVL 336
Query: 189 KCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRL-RERP 247
SQ +LE+ + +L++ I DI+ HAE+HF Y+ YC N+ + LQ+L
Sbjct: 337 GASQRFFEDLEQRHKAQVLVEDISDILEEHAEKHFHPYIAYCSNEVYQQRTLQKLISSNA 396
Query: 248 AFATALK 254
AF AL+
Sbjct: 397 AFREALR 403
>UniRef50_O94989 Cluster: Rho guanine nucleotide exchange factor 15;
n=17; Eutheria|Rep: Rho guanine nucleotide exchange
factor 15 - Homo sapiens (Human)
Length = 841
Score = 90.6 bits (215), Expect = 3e-17
Identities = 69/205 (33%), Positives = 95/205 (46%), Gaps = 19/205 (9%)
Query: 53 EPLYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPS-AMALVSPRGPARTL 111
EPLYQ Y AA + G+ S P PA A P GP TL
Sbjct: 350 EPLYQTYRAAVLSEELWGVGEDGS--------------PSPANAGDAPTFPRPPGPRNTL 395
Query: 112 WCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHI 171
W E + +L+P ++R+QE+ FE++TSEASYL SL +L FV A RD +
Sbjct: 396 WQELPAVQASGL-LDTLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDT-L 453
Query: 172 LPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCE 231
PRD LFS + V+ S+ + L + + + +CD+V HA F VYV Y
Sbjct: 454 TPRDH-HTLFSNVQRVQGVSERFLATLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVR 512
Query: 232 NQTLMVKALQRLRE-RPAFATALKR 255
NQ + RL + F+ L+R
Sbjct: 513 NQQYQEETYSRLMDTNVRFSAELRR 537
>UniRef50_Q8IW93 Cluster: Rho guanine nucleotide exchange factor 19;
n=20; Theria|Rep: Rho guanine nucleotide exchange factor
19 - Homo sapiens (Human)
Length = 802
Score = 90.2 bits (214), Expect = 4e-17
Identities = 69/208 (33%), Positives = 101/208 (48%), Gaps = 12/208 (5%)
Query: 55 LYQFYN-AAKVESIYRETGDSDSDGYEA-GVPGAQAPPPEPARPSAM--ALVSPRGPART 110
LYQ Y+ A + R+ + + G EA G PP PS+ A S RG +
Sbjct: 294 LYQEYSDVASARELRRQQREEEGPGDEAEGAEEGPGPPRANLSPSSSFRAQRSARGSTFS 353
Query: 111 LWCE--SRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRD 168
LW + R S L ++S +LQEAKFEL+TSEASY++SL+V F+ +
Sbjct: 354 LWQDIPDVRGSGVLATLSL---RDCKLQEAKFELITSEASYIHSLSVAVGHFLGSAELSE 410
Query: 169 PHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVK 228
L D + LFS + V+ S+ + +LE+ + ++L +CD+V H +VY+
Sbjct: 411 --CLGAQDKQWLFSKLPEVKSTSERFLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLP 468
Query: 229 YCENQTLMVKALQR-LRERPAFATALKR 255
Y NQ + QR L E P F L R
Sbjct: 469 YVTNQAYQERTYQRLLLENPRFPGILAR 496
>UniRef50_A3QJZ2 Cluster: Novel protein similar to vertebrate Rho
guanine nucleotide exchange factor (GEF) 15; n=13;
Euteleostomi|Rep: Novel protein similar to vertebrate
Rho guanine nucleotide exchange factor (GEF) 15 - Danio
rerio (Zebrafish) (Brachydanio rerio)
Length = 515
Score = 89.4 bits (212), Expect = 8e-17
Identities = 53/155 (34%), Positives = 82/155 (52%), Gaps = 5/155 (3%)
Query: 103 SPRGPAR-TLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFV 161
S RGP TLW + + L +K+ QE+ FE+LTSEASYL SL VL+ F+
Sbjct: 58 SKRGPEEITLW-QDLPVVKESGMLHKLTRTEKQRQESMFEVLTSEASYLRSLRVLKDHFL 116
Query: 162 AHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEE 221
+ ++ D ++LFS +L V + S+ + +L K E++++ + DI+ H+E
Sbjct: 117 GSRELNETLVI--HDRKVLFSNLLQVYEVSERFIRDLLKRVDESVVISDVSDIIYEHSEN 174
Query: 222 HFQVYVKYCENQTLMVKALQRLRE-RPAFATALKR 255
HF VY+ Y NQ K +L E FA ++R
Sbjct: 175 HFSVYIDYVRNQQYQEKTYSKLMESNTDFAVVMRR 209
>UniRef50_Q4TC03 Cluster: Chromosome undetermined SCAF7065, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF7065, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 885
Score = 88.2 bits (209), Expect = 2e-16
Identities = 67/210 (31%), Positives = 101/210 (48%), Gaps = 12/210 (5%)
Query: 53 EPLYQFYNAAKV-ESIYRETGDSDSDGYEAGVPG-----AQAPPPEPARPSAMALVSPRG 106
EPLYQ Y A+ + + I R+T + PG A P + ++ SP G
Sbjct: 379 EPLYQTYRASVISKEIRRQTVCRNISKTSIDFPGDWAARQTATATGNGAPRSSSMASP-G 437
Query: 107 PARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAF 166
+ TLW + + + L + + QE+ FE+LTSEASYL SL VL F
Sbjct: 438 QS-TLW-QDLSNVRESGVLERLTAEECKYQESMFEVLTSEASYLRSLRVLIEHFWDSRDL 495
Query: 167 RDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVY 226
+ I+ D + LFS+IL VR+ S+ + +LE E+++ ICDI+ +HA+ +F Y
Sbjct: 496 EETMIIR--DKKTLFSSILRVREVSERFLKDLEDRIFEDVVFSDICDIIHYHAQHNFPTY 553
Query: 227 VKYCENQTLMVKALQRL-RERPAFATALKR 255
+ Y NQ K L + FA + R
Sbjct: 554 IDYVRNQIYQEKTYTTLIKNNAQFAAVISR 583
>UniRef50_A5X5J0 Cluster: Rho guanine nucleotide exchange factor 19;
n=4; Tetrapoda|Rep: Rho guanine nucleotide exchange
factor 19 - Xenopus laevis (African clawed frog)
Length = 856
Score = 87.4 bits (207), Expect = 3e-16
Identities = 62/191 (32%), Positives = 96/191 (50%), Gaps = 8/191 (4%)
Query: 55 LYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCE 114
LYQ Y+ + + D+ G E V G+ P+ S + S RG +LW +
Sbjct: 352 LYQEYSDVAINREIQRQKREDTAGDEEEVTGSPKSNLSPSS-SFRSQRSSRGSTFSLWQD 410
Query: 115 --SRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHIL 172
R S L ++L +++LQEAKFEL+TSEASY++SL++ + P +
Sbjct: 411 IPDVRGSGLL---NTLTAHERKLQEAKFELVTSEASYVHSLSIAVDHLLNSPELNECLGA 467
Query: 173 PRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCEN 232
W LFS + V++ S+ + +LE+ + +IL +CDIV HH E +VY+ Y N
Sbjct: 468 QEKQW--LFSKLPEVKEISERFLMDLEERLERDILHFDVCDIVLHHCPELRRVYLPYVTN 525
Query: 233 QTLMVKALQRL 243
Q + QRL
Sbjct: 526 QAYQEQTYQRL 536
>UniRef50_UPI0000F2BEF5 Cluster: PREDICTED: similar to Rho guanine
nucleotide exchange factor (GEF) 15,; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to Rho guanine
nucleotide exchange factor (GEF) 15, - Monodelphis
domestica
Length = 834
Score = 87.0 bits (206), Expect = 4e-16
Identities = 56/147 (38%), Positives = 79/147 (53%), Gaps = 7/147 (4%)
Query: 101 LVSPRGPARTLWCE--SRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLES 158
L P P TLW E + R S L +L+P ++R+QE+ FE++TSEASYL SL +L
Sbjct: 370 LGEPSEPRNTLWQELPTVRESGLL---KTLSPEERRMQESLFEVVTSEASYLRSLQLLMD 426
Query: 159 QFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHH 218
FV + RD + PRD LFS + V+ S+ + L + + + +CD+V H
Sbjct: 427 TFVLSASLRDT-LTPRDH-HTLFSNVHRVQSVSERFLGVLLSRVRSSPHISDLCDVVHAH 484
Query: 219 AEEHFQVYVKYCENQTLMVKALQRLRE 245
AE F VYV Y NQ + +RL E
Sbjct: 485 AEGPFSVYVDYVRNQQYQEETYRRLME 511
>UniRef50_Q4SME7 Cluster: Chromosome 8 SCAF14552, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8
SCAF14552, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 775
Score = 86.6 bits (205), Expect = 5e-16
Identities = 58/170 (34%), Positives = 85/170 (50%), Gaps = 8/170 (4%)
Query: 89 PPPEPARPSAMALVSPRGPARTLWCE--SRRSSTPLCSVSSLAPAQKRLQEAKFELLTSE 146
PP RPS+ L + TLW E R+S+ L L Q+RLQE +FE++TSE
Sbjct: 328 PPKIEGRPSSPRLSISLTKSSTLWRELPGVRNSSEL---EELTEDQRRLQEVRFEVVTSE 384
Query: 147 ASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENI 206
ASY SL+++ FV +L D LFS + VR S +++LE+ + +I
Sbjct: 385 ASYCRSLDIVVEHFVKSKQLGA--LLGNQDRNWLFSRLADVRAISHSFLSKLEERLESDI 442
Query: 207 LLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRL-RERPAFATALKR 255
+ +CDI+ H + VYV Y NQ+ QRL E P F +++
Sbjct: 443 MSFTVCDIIAKHCQRFKMVYVPYLTNQSYQDATYQRLMNENPGFKRIVEK 492
>UniRef50_UPI0000F2E47F Cluster: PREDICTED: similar to zinc finger
protein; n=1; Monodelphis domestica|Rep: PREDICTED:
similar to zinc finger protein - Monodelphis domestica
Length = 1637
Score = 85.8 bits (203), Expect = 9e-16
Identities = 61/191 (31%), Positives = 90/191 (47%), Gaps = 7/191 (3%)
Query: 55 LYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCE 114
LYQ Y+ + + DS + Q P P P + + +LW +
Sbjct: 1136 LYQEYSDVALNKEIQSQQRLDSLSEVSSPASPQQPRKSPVIPDSYLQRLSIASSASLWQD 1195
Query: 115 SRR--SSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHIL 172
R +ST L S++ ++LQEAKFEL+ SEASYL SL+V F P R L
Sbjct: 1196 IPRVRNSTMLLSMTH---ENQKLQEAKFELIMSEASYLRSLHVAVDHFQLSPQLRAT--L 1250
Query: 173 PRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCEN 232
+ + LFS + VR S +++LE+ ++ NI +CD+V HA +VY+ Y N
Sbjct: 1251 SNQEHQWLFSRLQDVRDVSTTFLSDLEENFEHNIFTFHVCDVVLTHAPAFRRVYLPYVTN 1310
Query: 233 QTLMVKALQRL 243
QT + Q L
Sbjct: 1311 QTYQERTFQTL 1321
>UniRef50_UPI0000E2181D Cluster: PREDICTED: rho guanine nucleotide
exchange factor 5; n=5; Eutheria|Rep: PREDICTED: rho
guanine nucleotide exchange factor 5 - Pan troglodytes
Length = 1754
Score = 83.4 bits (197), Expect = 5e-15
Identities = 57/168 (33%), Positives = 86/168 (51%), Gaps = 15/168 (8%)
Query: 86 AQAPPPEPARPSAMALVSPRG--------PARTLWCESR--RSSTPLCSVSSLAPAQKRL 135
++ P P R ALVS + +LW E R+ST L S++ ++L
Sbjct: 1276 SETPGPSSPRQPRKALVSSESYLQRLSMASSGSLWQEIPVVRNSTVLLSMTH---EDQKL 1332
Query: 136 QEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLM 195
QE KFEL+ SEASYL SLN+ F + R L + + LFS + VR S + +
Sbjct: 1333 QEVKFELIVSEASYLRSLNIAVDHFQLSTSLRAT--LSNQEHQWLFSRLQDVRDVSAMFL 1390
Query: 196 NELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRL 243
++LE+ ++ NI +CD+V +HA + +VY+ Y NQT + Q L
Sbjct: 1391 SDLEENFENNIFSFQVCDVVLNHAPDFRRVYLPYVTNQTYQERTFQSL 1438
>UniRef50_UPI0000F210FE Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 873
Score = 82.6 bits (195), Expect = 9e-15
Identities = 67/205 (32%), Positives = 103/205 (50%), Gaps = 14/205 (6%)
Query: 55 LYQFYNAAKVE-SIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWC 113
LYQ Y+ + I R+ G E G ++ P PS+ + S RG A +LW
Sbjct: 457 LYQEYSDVAINREIQRQQGAEPGTDEERG----ESVSPGNLSPSS-SFRSSRGSAFSLWQ 511
Query: 114 E--SRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHI 171
+ RSS L + S+ +++LQEAKFEL+TSEASY+ SL++ F+ +
Sbjct: 512 DIPDVRSSGQLDNFSN---EERKLQEAKFELVTSEASYIRSLSIAVDHFMMSSELCE--C 566
Query: 172 LPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCE 231
L + + LFS + V++ S+ + +LE+ + +IL +CDIV H +VY+ Y
Sbjct: 567 LGTQERQWLFSKLPDVKEVSERFLQDLERRLEGDILRFDVCDIVLDHCPALRRVYLPYVT 626
Query: 232 NQTLMVKALQR-LRERPAFATALKR 255
NQ + QR L+E F L R
Sbjct: 627 NQAYQEQTYQRLLQENARFPGILAR 651
>UniRef50_Q12774 Cluster: Rho guanine nucleotide exchange factor 5;
n=25; Tetrapoda|Rep: Rho guanine nucleotide exchange
factor 5 - Homo sapiens (Human)
Length = 519
Score = 82.2 bits (194), Expect = 1e-14
Identities = 57/168 (33%), Positives = 85/168 (50%), Gaps = 15/168 (8%)
Query: 86 AQAPPPEPARPSAMALVSPRG--------PARTLWCESR--RSSTPLCSVSSLAPAQKRL 135
++ P P R ALVS + +LW E R+ST L S++ ++L
Sbjct: 41 SETPGPSSPRQPRKALVSSESYLQRLSMASSGSLWQEIPVVRNSTVLLSMTH---EDQKL 97
Query: 136 QEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLM 195
QE KFEL+ SEASYL SLN+ F + R L + + LFS + VR S +
Sbjct: 98 QEVKFELIVSEASYLRSLNIAVDHFQLSTSLRAT--LSNQEHQWLFSRLQDVRDVSATFL 155
Query: 196 NELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRL 243
++LE+ ++ NI +CD+V +HA + +VY+ Y NQT + Q L
Sbjct: 156 SDLEENFENNIFSFQVCDVVLNHAPDFRRVYLPYVTNQTYQERTFQSL 203
>UniRef50_UPI0000ECD505 Cluster: Rho guanine nucleotide exchange
factor (GEF) 19; n=2; Gallus gallus|Rep: Rho guanine
nucleotide exchange factor (GEF) 19 - Gallus gallus
Length = 520
Score = 78.2 bits (184), Expect = 2e-13
Identities = 48/125 (38%), Positives = 68/125 (54%), Gaps = 3/125 (2%)
Query: 132 QKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCS 191
+++LQEAKFEL+ SEASYL SLNV F + IL + + LFS + VR S
Sbjct: 97 EQKLQEAKFELIMSEASYLRSLNVAVDHFQRSAELQA--ILSNQERQWLFSRLQDVRDVS 154
Query: 192 QLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPA-FA 250
+ +LE ++E++ +CD+ HA E +VY+ Y NQT + QRL A F
Sbjct: 155 ASFLFDLEHKFEEDMFTFRVCDVALKHAPEFRRVYLPYVTNQTYQEQTFQRLLSGNAGFQ 214
Query: 251 TALKR 255
L+R
Sbjct: 215 QVLER 219
>UniRef50_Q4SPQ5 Cluster: Chromosome 16 SCAF14537, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 16
SCAF14537, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 936
Score = 77.8 bits (183), Expect = 3e-13
Identities = 54/165 (32%), Positives = 84/165 (50%), Gaps = 7/165 (4%)
Query: 92 EPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSS-LAPAQKRLQEAKFELLTSEASYL 150
EP +P +V R P RT W S+ S +S ++ +++ QEA FE+++SE SYL
Sbjct: 463 EP-KPDKDIVVQYR-PIRTSW--SQLSVVKKNGLSERISQEERKRQEAIFEVISSEHSYL 518
Query: 151 NSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQG 210
+SL +L F + + + + LFS I V + SQ ELE+ Q++I++
Sbjct: 519 HSLEILIRMFKNSAELSET--MTKTEHHHLFSNISDVCEASQKFFKELEERHQQSIVIDS 576
Query: 211 ICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPAFATALKR 255
I DIV A+ F Y+ YC N+ + LQ+L + F L R
Sbjct: 577 ISDIVCKRAQSSFDPYITYCSNEVYQQRTLQKLVSKKPFKDVLTR 621
>UniRef50_Q6Q8Q8 Cluster: SH3-containing guanine nucleotide exchange
factor; n=26; Tetrapoda|Rep: SH3-containing guanine
nucleotide exchange factor - Homo sapiens (Human)
Length = 871
Score = 77.4 bits (182), Expect = 3e-13
Identities = 52/151 (34%), Positives = 76/151 (50%), Gaps = 6/151 (3%)
Query: 107 PARTLWCESRRSSTPLCSVS-SLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPA 165
P R+ W S+ S+ +S +++ +++ QEA FE+++SE SYL SL +L F
Sbjct: 413 PLRSTW--SQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKE 470
Query: 166 FRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQV 225
D + + + LFS I V + S+ ELE Q NI + I DIV H F
Sbjct: 471 LSDT--MTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDP 528
Query: 226 YVKYCENQTLMVKALQR-LRERPAFATALKR 255
YVKYC N+ + LQ+ L P+F L R
Sbjct: 529 YVKYCTNEVYQQRTLQKLLATNPSFKEVLSR 559
>UniRef50_Q5TEV1 Cluster: Rho guanine nucleotide exchange factor
(GEF) 19; n=3; Catarrhini|Rep: Rho guanine nucleotide
exchange factor (GEF) 19 - Homo sapiens (Human)
Length = 306
Score = 74.1 bits (174), Expect = 3e-12
Identities = 56/179 (31%), Positives = 85/179 (47%), Gaps = 17/179 (9%)
Query: 85 GAQAPPPEPARPSAMALVSPRGPARTLW------CESRRSSTPL-CSVSSLAPAQKRLQE 137
G +P P AR + + +G R +W CE+R S C + L +
Sbjct: 15 GRGSPGPPGAR---LGVGLEKGRGREVWRPGVWGCEARASEVNWSCPFDPVCA----LPQ 67
Query: 138 AKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNE 197
AKFEL+TSEASY++SL+V F+ + L D + LFS + V+ S+ + +
Sbjct: 68 AKFELITSEASYIHSLSVAVGHFLGSAELSE--CLGAQDKQWLFSKLPEVKSTSERFLQD 125
Query: 198 LEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQR-LRERPAFATALKR 255
LE+ + ++L +CD+V H +VY+ Y NQ + QR L E P F L R
Sbjct: 126 LEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQERTYQRLLLENPRFPGILAR 184
>UniRef50_UPI0000F1FF96 Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 737
Score = 73.3 bits (172), Expect = 5e-12
Identities = 51/151 (33%), Positives = 75/151 (49%), Gaps = 7/151 (4%)
Query: 96 PSAMALVSPRGPARTLWCESRR-SSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLN 154
PS +S P TLW + ++P + L ++RLQE +FE++TSEASY SL+
Sbjct: 295 PSPRLSISASSP--TLWQDLPGVRNSP--EIVELTEDERRLQEVRFEVVTSEASYCRSLD 350
Query: 155 VLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDI 214
++ FV IL D LFS + VR S M+ LE+ + ++L +CDI
Sbjct: 351 IVVENFVLSKQLNA--ILSSQDKNWLFSRLNDVRAISHSFMSHLEENVERDMLHFTVCDI 408
Query: 215 VRHHAEEHFQVYVKYCENQTLMVKALQRLRE 245
+ + VYV Y NQ+ K QRL +
Sbjct: 409 IIKYCPRFRNVYVPYLTNQSYQDKTYQRLMD 439
>UniRef50_Q4RXA2 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 11
SCAF14979, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 334
Score = 66.9 bits (156), Expect = 5e-10
Identities = 44/124 (35%), Positives = 69/124 (55%), Gaps = 5/124 (4%)
Query: 134 RLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQL 193
RLQE+ FEL+ SEASYL SL V + F A A R L R + LFS IL V SQ
Sbjct: 7 RLQESMFELVASEASYLRSLGVAANHFYASGALR--RTLSRVEHHGLFSNILGVMAASQH 64
Query: 194 LMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKAL--QRLRERPAFAT 251
+ +LE + ++++ + D+V H ++Y+ Y N + +AL Q L++ AF++
Sbjct: 65 FLLDLEARLERSVIIPQVGDVVLQHCPAFRRLYMPYVTNM-MYQEALVDQLLQQNRAFSS 123
Query: 252 ALKR 255
+++
Sbjct: 124 LVRK 127
>UniRef50_Q4S6V2 Cluster: Chromosome 14 SCAF14723, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
SCAF14723, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1484
Score = 47.2 bits (107), Expect = 4e-04
Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
E+L +E +Y+ L + ++ + + + L +D E LF I + ++ L++ELEK
Sbjct: 115 EILDTERTYVQDLRSIVEDYLENISNQSRLALSSEDKEALFGNIQDIYHFNRDLLHELEK 174
Query: 201 CWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPAFA 250
C + + + C + + E F +Y +YC N V AL A A
Sbjct: 175 CHADPVAI-AECFVSK---SEEFHIYTQYCTNYPRSVAALTECMRNKALA 220
>UniRef50_Q5K7V4 Cluster: Signal transducer, putative; n=2;
Filobasidiella neoformans|Rep: Signal transducer,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1526
Score = 46.8 bits (106), Expect = 5e-04
Identities = 44/169 (26%), Positives = 74/169 (43%), Gaps = 10/169 (5%)
Query: 93 PARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNS 152
P + S + L +P W E PL + L+P Q+ + L+SE +Y
Sbjct: 364 PTKESIIPLPTPVSIRHDDWKED---IDPLM-LRDLSPRAITRQDVIRQALSSELAYEAD 419
Query: 153 LNVLESQFVAHPAFRDPHILP----RDDW-EILFSTILPVRKCSQLLMNELEKCWQENIL 207
L+++E F+ H DP I+P R+++ +F L +R S+ L+ E +E L
Sbjct: 420 LSIMEDLFITHLRLADPPIIPDPIHREEFIHEVFHNALELRAASKRLIEEFTIRQREQPL 479
Query: 208 LQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQR-LRERPAFATALKR 255
+Q + D+ A E +Y +Y + AL + L E F +R
Sbjct: 480 IQFVGDLFLQAATEFRNIYPEYTGSLPQAEAALSKELEENTEFRLYTER 528
>UniRef50_Q49U75 Cluster: PDZ-RhoGEF; n=2; Danio rerio|Rep:
PDZ-RhoGEF - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 1417
Score = 42.7 bits (96), Expect = 0.009
Identities = 34/132 (25%), Positives = 67/132 (50%), Gaps = 11/132 (8%)
Query: 125 VSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTI 184
++SL + Q +EL T+E S+L +L VL+ F + +L ++ +F +
Sbjct: 724 LASLTSREIDRQAVIYELFTTEVSHLRTLRVLDQVFYQ----KMQSVLSPEELSCIFLNL 779
Query: 185 LPVRKCSQLLMNELEKCWQENILLQGICDIV----RHHAEEHFQVYVKY-CENQTLMVKA 239
V + L ++KC +E++++QGI DI+ A + F+ V + C Q+ ++
Sbjct: 780 RQVYELHASLCESMKKC-RESVIVQGIGDIMLARFEGEAGDQFEEQVSHLCSQQSPALEL 838
Query: 240 LQ-RLRERPAFA 250
++ + R+ P FA
Sbjct: 839 IKNKQRKDPRFA 850
>UniRef50_A7RTF1 Cluster: Predicted protein; n=8; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 430
Score = 42.3 bits (95), Expect = 0.012
Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 1/105 (0%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
E+L +E Y+ +L+ + ++ A + + D +LFS I + + Q L+ +LE
Sbjct: 99 EILNTEKDYVKNLSDVVEGYLCQ-AQKRVDMFSEDQIYLLFSNIEQIYEFHQKLLLQLED 157
Query: 201 CWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRE 245
C+ ++ + V +E FQ+Y +YC N + L+ L E
Sbjct: 158 CYLKDNPCDSMIGRVFLENKEGFQIYSEYCNNHPHAIAELKTLCE 202
>UniRef50_Q1ZXN6 Cluster: Pleckstrin homology (PH) domain-containing
protein; n=2; Dictyostelium discoideum|Rep: Pleckstrin
homology (PH) domain-containing protein - Dictyostelium
discoideum AX4
Length = 1145
Score = 41.5 bits (93), Expect = 0.020
Identities = 33/117 (28%), Positives = 60/117 (51%), Gaps = 8/117 (6%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTI-LPVRKCSQLLMNELE 199
E++ +E Y+ LN++ + F+ P ++ I+P D I+FS I L + +LL + L+
Sbjct: 462 EIINTEKDYIADLNIIVN-FILTP-LKESKIIPDKDISIIFSNIQLLLNVNKELLSDLLQ 519
Query: 200 KCWQENIL-LQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRER-PAFATALK 254
K E G C I + ++ ++Y YC NQT+ + R ++ P+F L+
Sbjct: 520 KAPDEKPNHTVGTCFI---YFFKYLKIYSGYCANQTISADHIARCSKKIPSFKQFLE 573
>UniRef50_Q8WZX1 Cluster: Related to DNA repair endonuclease rad2;
n=2; Neurospora crassa|Rep: Related to DNA repair
endonuclease rad2 - Neurospora crassa
Length = 1037
Score = 41.5 bits (93), Expect = 0.020
Identities = 27/88 (30%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Query: 52 HEPLYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTL 111
H PL++ + A + S++ E D D + + + P P RP A A +SP AR
Sbjct: 857 HSPLFRRHKA-DLNSLHEEEDSDDDDSFVSIGALTRQKSPSPLRPRATATLSPSSSARRE 915
Query: 112 WCESRRSSTPLCSVSSLAPAQKRLQEAK 139
+RSS L SS P+ + Q A+
Sbjct: 916 LAREKRSSPAL--RSSPVPSPRTFQRAE 941
>UniRef50_Q0W767 Cluster: Putative uncharacterized protein; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
uncharacterized protein - Uncultured methanogenic
archaeon RC-I
Length = 335
Score = 40.7 bits (91), Expect = 0.035
Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
Query: 59 YNAAKVESIYRETGDSDSDGY--EAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESR 116
Y ++SI + TG + + Y E G P A+A PPEPARP + + PA
Sbjct: 162 YGDKAIDSIKKATGKASAAIYFLEGGAPIAEALPPEPARPVKEKPIEVQAPA-------- 213
Query: 117 RSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLN 154
+ TP+ + APA+ R + EL + S N L+
Sbjct: 214 PAPTPVPAPVPAAPAEAREAPRQTELKVATGSTANLLH 251
>UniRef50_UPI00015B50AC Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 1; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to FYVE, RhoGEF and
PH domain containing 1 - Nasonia vitripennis
Length = 777
Score = 39.5 bits (88), Expect = 0.081
Identities = 34/132 (25%), Positives = 64/132 (48%), Gaps = 5/132 (3%)
Query: 126 SSLAPAQKRLQEAKFELLTSEASYLNSLNVLES--QFVAHPAFRDPHILPRDDWEILFST 183
SS+ +K+ + ELLT+E Y+N L +++ QF R + P D + +FS
Sbjct: 223 SSIEAKRKKARHIADELLTTEKKYVNILYLIDQIFQFRVDQENRAHPMFPPDTVQQMFSN 282
Query: 184 ILPVRKC-SQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQR 242
I + K + L+ +LE + I DI+++ A ++Y +Y +N + +
Sbjct: 283 IKSIYKFHNDFLLPQLETRIEAWDADPRIGDIMKNFA-PFLKMYTEYVKNFDYAINLIST 341
Query: 243 LRER-PAFATAL 253
L+++ P FA +
Sbjct: 342 LQQKVPRFAAII 353
>UniRef50_UPI000065FF36 Cluster: Homolog of Homo sapiens "pleckstrin
homology domain containing, family G (with RhoGef
domain) member 3 (PLEKHG3), mRNA; n=3;
Clupeocephala|Rep: Homolog of Homo sapiens "pleckstrin
homology domain containing, family G (with RhoGef
domain) member 3 (PLEKHG3), mRNA - Takifugu rubripes
Length = 2512
Score = 39.5 bits (88), Expect = 0.081
Identities = 26/117 (22%), Positives = 53/117 (45%), Gaps = 4/117 (3%)
Query: 135 LQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLL 194
L E++ +E Y+ L ++ ++AH + ++ + LF I + + + L
Sbjct: 10 LDRVLMEIIETERMYVRDLRMIVEDYLAHIIDQCELLIGPEQVCALFGNIEDIYEFNSEL 69
Query: 195 MNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPAFAT 251
+ L+ C + + + C I++ E F++Y +YC N V AL + + AT
Sbjct: 70 LQALDLCDNDAVAVAR-CFIMKG---EFFEIYTQYCTNYPNSVAALTECMRKKSLAT 122
>UniRef50_UPI0000D5630B Cluster: PREDICTED: similar to CG7323-PA; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to CG7323-PA
- Tribolium castaneum
Length = 1625
Score = 39.1 bits (87), Expect = 0.11
Identities = 34/116 (29%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Query: 126 SSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPH-ILPRDDWEILFSTI 184
S L Q++ Q A +EL+TSE SY+ +L V+ F+A H +L D E LFS I
Sbjct: 962 SELNEKQQQQQTALWELITSEVSYIRTLKVVTDLFLACLRDLQSHKLLIEIDREKLFSNI 1021
Query: 185 LPVRKCSQLLMNE----LEKCWQENILLQGICDIVRHHAEEH--FQVYVKYCENQT 234
+ + + L + +++ I ++ ++ H FQ Y KYC Q+
Sbjct: 1022 TEILDANVMFWRNTLFPLIRDMRQHKRTTCIENMAEGFSKIHETFQPYYKYCAEQS 1077
>UniRef50_Q9ULL1 Cluster: Pleckstrin homology domain-containing
family G member 1; n=29; Eumetazoa|Rep: Pleckstrin
homology domain-containing family G member 1 - Homo
sapiens (Human)
Length = 1385
Score = 39.1 bits (87), Expect = 0.11
Identities = 30/136 (22%), Positives = 55/136 (40%), Gaps = 8/136 (5%)
Query: 107 PARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAF 166
P R W + + S+ +P + E+L +E +Y+ L + ++
Sbjct: 86 PPRAQWRVDSNGAPKTIADSATSPKLLYVDRVVQEILETERTYVQDLKSIVEDYL--DCI 143
Query: 167 RDPHILP--RDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQ 224
RD LP ++ LF I + + L+ +LE C + + + C + + E F
Sbjct: 144 RDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCENDPVAIAE-CFVSK---SEEFH 199
Query: 225 VYVKYCENQTLMVKAL 240
+Y +YC N V L
Sbjct: 200 IYTQYCTNYPRSVAVL 215
>UniRef50_UPI0000DB6D3E Cluster: PREDICTED: similar to RhoGEF2
CG9635-PD, isoform D; n=1; Apis mellifera|Rep: PREDICTED:
similar to RhoGEF2 CG9635-PD, isoform D - Apis mellifera
Length = 1768
Score = 38.7 bits (86), Expect = 0.14
Identities = 30/127 (23%), Positives = 62/127 (48%), Gaps = 7/127 (5%)
Query: 125 VSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTI 184
++ L+ A+K+ QE EL +E S++ +L VL F H + +LP D ++LFS +
Sbjct: 1052 LARLSNAEKKRQEVINELFHTERSHVRALRVLSHVF--HKPLLESQVLPLDQIQLLFSNL 1109
Query: 185 LPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAE-EHFQVYVK----YCENQTLMVKA 239
+ +++ +EN + + D++ + E+ + + + YC Q + + A
Sbjct: 1110 DEMVTIHSRFNQAMKRKKKENPCVGDVGDLLLDMFDGENGETFERAASIYCAKQQVALDA 1169
Query: 240 LQRLRER 246
L+ R +
Sbjct: 1170 LRDRRRK 1176
>UniRef50_Q4P2N2 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1444
Score = 38.3 bits (85), Expect = 0.19
Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 7/124 (5%)
Query: 115 SRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAH----PAFRDPH 170
S SS+P S RL EL+ +E SY+ ++VL ++ RD
Sbjct: 208 SAASSSPSTSAKPSNIDPSRLFGRVQELIDTERSYVKRIDVLYHKYAVPLRTLAKDRDRA 267
Query: 171 ILPRDDWEILFSTILPVRKCSQLLMNELEKCWQE--NILLQGICDIVRHHAEEHFQVYVK 228
I+P + + LF I + ++ +N+LE+ + LL G+ D++ +H F Y +
Sbjct: 268 IIPLYEAQKLFGNIGEIAGANRAFLNDLERLASQGHQALLAGLGDVLYNHM-SCFSCYTE 326
Query: 229 YCEN 232
Y N
Sbjct: 327 YFAN 330
>UniRef50_A7RUA3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1695
Score = 37.9 bits (84), Expect = 0.25
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 6/132 (4%)
Query: 114 ESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILP 173
ES +S + + SS ++ Q+ ELL +E Y+ L F + ++ ++
Sbjct: 957 ESMQSLSQPPTRSSQQHMAEQRQKVLTELLNTERDYIRDLQTCLKYF--YEELKNTKVV- 1013
Query: 174 RDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQ 233
D E+LF + V + S L+ E Q++ Q + HAEE VY YC+N
Sbjct: 1014 --DAEVLFGNMHSVVETSTRLLGSFEAALQDD-KQQELGKCFAEHAEEIKSVYSTYCKNH 1070
Query: 234 TLMVKALQRLRE 245
+ L++ +
Sbjct: 1071 DDAIGLLEKYED 1082
>UniRef50_UPI00005887C8 Cluster: PREDICTED: similar to Rho guanine
nucleotide exchange factor 3; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Rho guanine
nucleotide exchange factor 3 - Strongylocentrotus
purpuratus
Length = 399
Score = 37.5 bits (83), Expect = 0.33
Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 3/105 (2%)
Query: 136 QEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLM 195
QEA FEL E ++ L ++ + A R IL + I+F ++ +R + L+
Sbjct: 64 QEAIFELFQGEVDLVDDLYLVMKTY--RDAMRSLQILTDQELNIIFGSLEELRMIHEELV 121
Query: 196 NELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKAL 240
+L+K N + + ++ +VYV YC NQ L K L
Sbjct: 122 CDLQKQRGNNGATEEVGKVLLKWLPLVTEVYVTYCTNQ-LAAKTL 165
>UniRef50_UPI000049A230 Cluster: hypothetical protein 13.t00058;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 13.t00058 - Entamoeba histolytica HM-1:IMSS
Length = 558
Score = 37.5 bits (83), Expect = 0.33
Identities = 24/102 (23%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Query: 133 KRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQ 192
KR + EL+ SEA Y++ + + ++ D HI+ +D +F + + ++
Sbjct: 5 KRTENILKELVESEARYISQMELGLFKYKEPIEKDDKHIIGSEDLRKMFMYYQDIIEFNK 64
Query: 193 LLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQT 234
L+ E + ++ L++ + + + E HF VY+KY + T
Sbjct: 65 QLLREFKDYLEKGELIKYVGTVFIAN-ENHFNVYIKYFKAST 105
>UniRef50_A6W4J7 Cluster: Diguanylate cyclase/phosphodiesterase with
GAF sensor; n=1; Kineococcus radiotolerans SRS30216|Rep:
Diguanylate cyclase/phosphodiesterase with GAF sensor -
Kineococcus radiotolerans SRS30216
Length = 964
Score = 37.1 bits (82), Expect = 0.43
Identities = 28/72 (38%), Positives = 37/72 (51%), Gaps = 8/72 (11%)
Query: 83 VPGAQAPPPEPARPSAMALVSPRGP--------ARTLWCESRRSSTPLCSVSSLAPAQKR 134
VP A A P PA P+A A +PRG ART+ + RS L SV++LA A
Sbjct: 610 VPAAPAAPAAPAAPAAPAARAPRGGDEEERVGLARTVLGATARSEGLLRSVTALAAAVCG 669
Query: 135 LQEAKFELLTSE 146
+ A F ++T E
Sbjct: 670 TEFASFNVVTEE 681
>UniRef50_Q8TCU6 Cluster: Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 1 protein;
n=33; Eukaryota|Rep: Phosphatidylinositol
3,4,5-trisphosphate-dependent Rac exchanger 1 protein -
Homo sapiens (Human)
Length = 1659
Score = 37.1 bits (82), Expect = 0.43
Identities = 44/175 (25%), Positives = 69/175 (39%), Gaps = 19/175 (10%)
Query: 78 GYEAGVPGA-QAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQ 136
G E G GA P+P P A A S GP R+ LC ++
Sbjct: 6 GSEPGGDGAGDCAHPDPRAPGAAAPSSGPGPCAAARESERQLRLRLCVLN---------- 55
Query: 137 EAKFELLTSEASYLNSLNVLESQFV----AHPAFRDPHILPRDDWEILFSTILPVRKCSQ 192
E+L +E Y+ +L L+S F+ + A L ++ ++LFS I + + +
Sbjct: 56 ----EILGTERDYVGTLRFLQSAFLHRIRQNVADSVEKGLTEENVKVLFSNIEDILEVHK 111
Query: 193 LLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERP 247
+ LE C Q V ++ F VY +YC N ++ L L + P
Sbjct: 112 DFLAALEYCLHPEPQSQHELGNVFLKFKDKFCVYEEYCSNHEKALRLLVELNKIP 166
>UniRef50_Q15811 Cluster: Intersectin-1; n=93; Eumetazoa|Rep:
Intersectin-1 - Homo sapiens (Human)
Length = 1721
Score = 37.1 bits (82), Expect = 0.43
Identities = 36/146 (24%), Positives = 67/146 (45%), Gaps = 9/146 (6%)
Query: 115 SRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPR 174
S++ + L + L P +++ Q EL+ +E +Y+N L ++ F + +L
Sbjct: 1218 SQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIF--QKPLMESELLTE 1275
Query: 175 DDWEILFSTILPVRKCSQLLMNEL---EKCWQENILLQGICDIVRHHAEEHFQVYVKYCE 231
+ ++F + C+ L+ L +K E + ++ I DI+ H Q Y+++C
Sbjct: 1276 KEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQL-PHMQPYIRFCS 1334
Query: 232 NQTLMVKAL--QRLRERPAFATALKR 255
Q L AL Q+ E P F +KR
Sbjct: 1335 RQ-LNGAALIQQKTDEAPDFKEFVKR 1359
>UniRef50_A7H758 Cluster: 4Fe-4S ferredoxin iron-sulfur binding
domain protein; n=3; Deltaproteobacteria|Rep: 4Fe-4S
ferredoxin iron-sulfur binding domain protein -
Anaeromyxobacter sp. Fw109-5
Length = 265
Score = 36.3 bits (80), Expect = 0.76
Identities = 20/43 (46%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 67 IYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPAR 109
I RE D D +A + A+AP EPA P A+A V+P PAR
Sbjct: 61 IEREAADFDEAAVKAHLARARAPAQEPA-PPALAAVAPPAPAR 102
>UniRef50_Q0IPQ9 Cluster: Os12g0174300 protein; n=1; Oryza sativa
(japonica cultivar-group)|Rep: Os12g0174300 protein -
Oryza sativa subsp. japonica (Rice)
Length = 251
Score = 36.3 bits (80), Expect = 0.76
Identities = 22/82 (26%), Positives = 37/82 (45%)
Query: 83 VPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFEL 142
+P P P P+ PS+ + R R L S SS+ S+ S +P+ R +
Sbjct: 19 LPPPPLPLPSPSSPSSSTTIPRRRHHRRLASSSSTSSSSTASIFSTSPSPSRRCSSSRAA 78
Query: 143 LTSEASYLNSLNVLESQFVAHP 164
+TS+ + S+ V+ + HP
Sbjct: 79 VTSDVTTTASVVVVPFSWELHP 100
>UniRef50_Q54ND2 Cluster: RhoGEF domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: RhoGEF
domain-containing protein - Dictyostelium discoideum AX4
Length = 1377
Score = 36.3 bits (80), Expect = 0.76
Identities = 31/118 (26%), Positives = 53/118 (44%), Gaps = 8/118 (6%)
Query: 143 LTSEASYLNSLNVLESQFVAHPAFRDPHI--LPRDDWEILFSTILPVRKCSQLLMNELEK 200
L++E YL LN L + ++A D + ++D +FS I P+ C + ELE
Sbjct: 612 LSAERQYLTGLNTLVTIYLAGLRTDDRLFSKIFKEDEIAIFSNIEPLYSCQSKFVEELES 671
Query: 201 C---WQE-NILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPAFATALK 254
C W E N G + ++++ Q+Y Y N + + + R ++ F LK
Sbjct: 672 CYKGWGEPNTPTLG--GVFFKNSQKMMQLYSVYITNFSKALLTISRCKQSKNFQAFLK 727
>UniRef50_Q54MM3 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 971
Score = 36.3 bits (80), Expect = 0.76
Identities = 29/104 (27%), Positives = 46/104 (44%), Gaps = 9/104 (8%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQ---LLMNE 197
E+LT+E +Y NSL+ F+ R I+ DD +FS + + + L+ E
Sbjct: 613 EILTTEQTYCNSLSTKIEVFIL--PLRSKSIISNDDLSTIFSNSEVIHQFNSGFLALLEE 670
Query: 198 LEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQ 241
W N Q I ++ ++ E Q Y Y N +KAL+
Sbjct: 671 KINNWSTN---QSIGEVF-NYLENSVQCYSTYVNNYNNSIKALE 710
>UniRef50_UPI0000E2546B Cluster: PREDICTED: hypothetical protein;
n=1; Pan troglodytes|Rep: PREDICTED: hypothetical
protein - Pan troglodytes
Length = 310
Score = 35.9 bits (79), Expect = 1.0
Identities = 20/54 (37%), Positives = 24/54 (44%)
Query: 78 GYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPA 131
G E PG+QA A P A VSP GP + L +S S SS P+
Sbjct: 96 GEEGAAPGSQASTESSAHPPTAAPVSPSGPGKALGISLNATSGKSQSQSSATPS 149
>UniRef50_Q571N4 Cluster: MKIAA0208 protein; n=1; Mus musculus|Rep:
MKIAA0208 protein - Mus musculus (Mouse)
Length = 356
Score = 35.9 bits (79), Expect = 1.0
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 4/68 (5%)
Query: 63 KVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPL 122
KV + + + G G P + PP P P A+ LV G AR +W +RR TP
Sbjct: 138 KVGMAHEQRAAQFNPGLGKGAPSLLSSPPSPLYPLALMLV---GAARRIWTMTRR-PTPW 193
Query: 123 CSVSSLAP 130
C + P
Sbjct: 194 CLPNESGP 201
>UniRef50_UPI000051ACFC Cluster: PREDICTED: similar to Pleckstrin
homology domain-containing family G member 1; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pleckstrin homology
domain-containing family G member 1 - Apis mellifera
Length = 1354
Score = 35.5 bits (78), Expect = 1.3
Identities = 25/125 (20%), Positives = 54/125 (43%), Gaps = 4/125 (3%)
Query: 130 PAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRK 189
P + ++ E++ +EA Y+ L + ++ + + LFS I + +
Sbjct: 253 PHRNPMERVLLEIVDTEAIYVEHLRQVIQGYLIFWRNDSASFMDQTQLSNLFSNIEDIFE 312
Query: 190 CSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPAF 249
++ + E+E+C + + + ++H + F+VY +YC N V L L +
Sbjct: 313 FNREFLKEIEECGLDPVSVANT--FIKH--KSGFKVYTEYCTNYPSTVSVLTDLMSQEKT 368
Query: 250 ATALK 254
A A +
Sbjct: 369 ACAFQ 373
>UniRef50_Q4RLN1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 729
Score = 35.5 bits (78), Expect = 1.3
Identities = 26/102 (25%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEI--LFSTILPVRKCSQLLMNEL 198
E++ +E Y+ L + ++AH D LP ++ LF I + + + L+ L
Sbjct: 128 EIIETERMYVKDLRSIVEDYLAH--IIDMSNLPIRPEQVCDLFGNIEDIYEFNSELLQSL 185
Query: 199 EKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKAL 240
+ C + + + C + + E+FQ+Y +YC N V AL
Sbjct: 186 DMCDSDPVAIAQ-CFVDK---SEYFQIYTQYCTNYPNSVAAL 223
>UniRef50_Q9XXM9 Cluster: Putative uncharacterized protein uig-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein uig-1 - Caenorhabditis elegans
Length = 919
Score = 35.5 bits (78), Expect = 1.3
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 135 LQEAKFELLTSEASYLNSLN-VLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQL 193
L ELL +E +Y+ LN V++ R+ + D LF I + ++
Sbjct: 224 LDRIAIELLDTERTYVEDLNAVIKGYMDFLVEDREKLKVTLDAISSLFGCIERIFAFNKQ 283
Query: 194 LMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPAFATAL 253
L N+L+ + + + C + + F+ Y++YC N M+ L L+++P A AL
Sbjct: 284 LYNQLDAADLDCVKMSR-CFV---ESSGKFEDYIEYCTNYHRMMSTLYHLQQQPLVARAL 339
Query: 254 K 254
+
Sbjct: 340 Q 340
>UniRef50_Q54XW8 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 874
Score = 35.5 bits (78), Expect = 1.3
Identities = 18/65 (27%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Query: 141 ELLTSEASYLNSLNVLESQFVAH-PAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELE 199
EL +E++Y+N L+ L F+ A + ILP DD++ +FS+I + K + +++++
Sbjct: 441 ELFETESTYVNHLSNLLKIFINPLKAKKGDSILPADDFDQIFSSIQTIYKTNSYFLDQVD 500
Query: 200 KCWQE 204
+ +++
Sbjct: 501 EIFKK 505
>UniRef50_Q1ZX99 Cluster: RhoGEF domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: RhoGEF
domain-containing protein - Dictyostelium discoideum AX4
Length = 1024
Score = 35.5 bits (78), Expect = 1.3
Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
E+L +E Y+ +LN+ +F P + I+ ++ ++FS I+ + + + ELEK
Sbjct: 258 EILKTETDYVKNLNIC-IKFYMEPLLQK-EIISKEQSRMIFSDIIIIYNFGKTFLEELEK 315
Query: 201 CWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRE 245
N + + +VY Y EN + A++ L++
Sbjct: 316 RCGNNWKIYTKLSDMFLSISSFLKVYSSYVENYDNSIAAIKDLKK 360
>UniRef50_Q96UR6 Cluster: GDP/GTP exchange factor Rom2p; n=1;
Kluyveromyces lactis|Rep: GDP/GTP exchange factor Rom2p
- Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 1227
Score = 35.5 bits (78), Expect = 1.3
Identities = 33/138 (23%), Positives = 67/138 (48%), Gaps = 8/138 (5%)
Query: 118 SSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRD-- 175
SS P SSL + + QEA +E+ ++E ++ SL +L F+ A + +I+P D
Sbjct: 525 SSVPEELWSSLTKREIKRQEAIYEVYSTEKKFVKSLEILRDTFMKKLA--ETNIIPADIR 582
Query: 176 --DWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQ 233
+ +F+ + + ++ L++ L + + + ++ GI DI+ F+ +V Y ++
Sbjct: 583 KNFIKHVFAHVNDIYSVNRRLLDALSERQKASPIVDGIGDILLRFV-PFFEPFVMYVASR 641
Query: 234 TLMVKALQRLRE-RPAFA 250
++ R P FA
Sbjct: 642 PYAKYLIETQRSVNPYFA 659
>UniRef50_Q3UWX6 Cluster: In vitro fertilized eggs cDNA, RIKEN
full-length enriched library, clone:7420449L11
product:hypothetical protein, full insert sequence; n=3;
Mus musculus|Rep: In vitro fertilized eggs cDNA, RIKEN
full-length enriched library, clone:7420449L11
product:hypothetical protein, full insert sequence - Mus
musculus (Mouse)
Length = 351
Score = 35.1 bits (77), Expect = 1.8
Identities = 20/57 (35%), Positives = 31/57 (54%), Gaps = 4/57 (7%)
Query: 194 LMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCEN----QTLMVKALQRLRER 246
L +LE QEN +QG C +++HH E+ +Y K E QT K ++R+ E+
Sbjct: 217 LKKKLEMLSQENKEMQGDCALLQHHVEDLKPIYKKQQEEDSDLQTQHQKHMERMEEK 273
>UniRef50_A0H1D5 Cluster: Putative uncharacterized protein; n=1;
Chloroflexus aggregans DSM 9485|Rep: Putative
uncharacterized protein - Chloroflexus aggregans DSM
9485
Length = 458
Score = 35.1 bits (77), Expect = 1.8
Identities = 27/76 (35%), Positives = 32/76 (42%), Gaps = 4/76 (5%)
Query: 60 NAAKVESIYRETGDSDSDGYEAGVPGAQA--PPPEPARPSAMALVSPRGPAR--TLWCES 115
+AA YR T S + GV + PPP PAR AL PR P T
Sbjct: 222 SAAPAAPAYRSTAPSPAGPTATGVEQRRTRRPPPSPARRPTAALRCPRSPHHRPTAAPRR 281
Query: 116 RRSSTPLCSVSSLAPA 131
R + P + SS APA
Sbjct: 282 HRQAPPPPAWSSAAPA 297
>UniRef50_Q6WKY8 Cluster: Guanine nucleotide exchange factor; n=2;
Entamoeba histolytica|Rep: Guanine nucleotide exchange
factor - Entamoeba histolytica
Length = 630
Score = 35.1 bits (77), Expect = 1.8
Identities = 25/106 (23%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
ELL++E SY+ LN++ F A P ++ D ++ +FS I + ++ + +K
Sbjct: 190 ELLSTEESYVQQLNLIVKLF-AEPVM-TKQLITMDQYKKIFSDIQMILSVNEQFLQSFQK 247
Query: 201 C---WQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRL 243
W + G+ ++ ++Y +YC+N +K L+ L
Sbjct: 248 VISQWNSESKIGGL--FIK--LAPFLKIYGEYCKNYPEALKVLKEL 289
>UniRef50_Q54DE0 Cluster: Calmodulin-binding protein; n=2;
Dictyostelium discoideum|Rep: Calmodulin-binding protein
- Dictyostelium discoideum AX4
Length = 1737
Score = 35.1 bits (77), Expect = 1.8
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 7/110 (6%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
EL+ +E Y+ LN++ F+ +P R+ +L D LFS I + + ++ LEK
Sbjct: 1396 ELIETERDYVRDLNIVVEVFL-NP-IREKQLLSAKDINSLFSNIEILFSINMNVLKALEK 1453
Query: 201 CWQENILLQGICDIVRHHAEEHF-QVYVKYCENQTLMVKAL--QRLRERP 247
++ L + I H+ ++Y YC NQ +K L ++++ +P
Sbjct: 1454 --DKDPLCENISVGQTFLDMSHYLKMYTTYCSNQQNALKILEEEKIKNQP 1501
>UniRef50_A0E1W1 Cluster: Chromosome undetermined scaffold_74, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_74,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 866
Score = 35.1 bits (77), Expect = 1.8
Identities = 31/117 (26%), Positives = 55/117 (47%), Gaps = 6/117 (5%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEI--LFSTILPVRKCSQLLMNEL 198
E+L +E +Y+N L VLE + + D+ I +F + +RK +Q +++
Sbjct: 37 EILYTELNYINDLGVLEDHTQLREILTNELPMRSDEKYISAIFMNVSDIRKENQKFYDQV 96
Query: 199 EKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQ-RLRERPAFATALK 254
K NI + I + + F+ Y YC N +KAL+ L+++P +LK
Sbjct: 97 -KSKAANINRNSV--IFDNVDVKGFETYYHYCRNYNDSLKALKLLLQKQPQLEHSLK 150
>UniRef50_P10911 Cluster: Proto-oncogene DBL (Proto-oncogene MCF-2)
[Contains: MCF2-transforming protein; DBL-transforming
protein]; n=36; Tetrapoda|Rep: Proto-oncogene DBL
(Proto-oncogene MCF-2) [Contains: MCF2-transforming
protein; DBL-transforming protein] - Homo sapiens
(Human)
Length = 925
Score = 35.1 bits (77), Expect = 1.8
Identities = 33/127 (25%), Positives = 60/127 (47%), Gaps = 11/127 (8%)
Query: 113 CESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVA---HPAFRD- 168
C+ +RSS P S+ + EL+ +E Y+ L + + A +P D
Sbjct: 474 CQEKRSSGPSSSLDNGNSLDVLKNHVLNELIQTERVYVRELYTVLLGYRAEMDNPEMFDL 533
Query: 169 -PHILPRDDWEILFSTILPVRKC-SQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVY 226
P +L R+ +ILF + + + + + ++ LE C + G C + R ++ FQ+Y
Sbjct: 534 MPPLL-RNKKDILFGNMAEIYEFHNDIFLSSLENCAHAPERV-GPCFLER---KDDFQMY 588
Query: 227 VKYCENQ 233
KYC+N+
Sbjct: 589 AKYCQNK 595
>UniRef50_UPI000155CE54 Cluster: PREDICTED: similar to ankyrin
repeat domain 26; n=3; Mammalia|Rep: PREDICTED: similar
to ankyrin repeat domain 26 - Ornithorhynchus anatinus
Length = 2492
Score = 34.7 bits (76), Expect = 2.3
Identities = 18/48 (37%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Query: 78 GYEAGVPGAQAPPPEPA----RPSAMALVSPRGPARTLWCESRRSSTP 121
G E GVP PP + A RP+A+A P+ P T+W TP
Sbjct: 192 GGEPGVPAPNPPPAKEAGWRLRPTALAGCCPQSPTATIWGTQEPPDTP 239
>UniRef50_UPI0000519B3F Cluster: PREDICTED: similar to FYVE, RhoGEF
and PH domain containing 4 isoform 1; n=1; Apis
mellifera|Rep: PREDICTED: similar to FYVE, RhoGEF and PH
domain containing 4 isoform 1 - Apis mellifera
Length = 729
Score = 34.7 bits (76), Expect = 2.3
Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 124 SVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLES--QFVAHPAFRDPHILPRDDWEILF 181
+ S L +K + ELL +E +Y+N L +++ QF R + P + + +F
Sbjct: 171 NTSYLDSKRKNARRVAEELLVTEKNYVNVLRLIDQVFQFKIDQENRAHPMFPPETVQHMF 230
Query: 182 STILPVRKC-SQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKAL 240
S I + K + L+ +L++ Q I DI+++ A ++Y +Y +N + +
Sbjct: 231 SNIKSIYKFHNDFLLPQLQERMQNWDSNPRIGDIMKNFA-PFLKMYTEYVKNFDYAMNLI 289
Query: 241 QRLRER 246
Q L+ +
Sbjct: 290 QSLQTK 295
>UniRef50_UPI000049976C Cluster: hypothetical protein 115.t00004;
n=2; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 115.t00004 - Entamoeba histolytica HM-1:IMSS
Length = 948
Score = 34.7 bits (76), Expect = 2.3
Identities = 23/93 (24%), Positives = 51/93 (54%), Gaps = 8/93 (8%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
E+ T+E +Y+ LN + ++ + P + I+ D+++ LF+ I + + + L ++E+
Sbjct: 644 EMYTTEKTYVQQLNQITNEIM--PIMKK--IMKDDEYQELFNNIGEIYEIHKTLFKQIEE 699
Query: 201 CWQE--NILLQGICDIVR--HHAEEHFQVYVKY 229
W+E +I L + DI +E + +Y++Y
Sbjct: 700 RWEEQKDIPLIIVSDIYNKFFSDKETYNIYMEY 732
>UniRef50_Q8PP92 Cluster: Putative uncharacterized protein XAC0796;
n=1; Xanthomonas axonopodis pv. citri|Rep: Putative
uncharacterized protein XAC0796 - Xanthomonas axonopodis
pv. citri
Length = 183
Score = 34.7 bits (76), Expect = 2.3
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 5/87 (5%)
Query: 87 QAPPP--EPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELLT 144
+AP P P + + L +P+G +R + R+ + +LAPA + + LT
Sbjct: 12 RAPCPCWPPGQGAQRGLGAPQGTSRRV---GRQRHGARATRLALAPATPAPRSTRSAPLT 68
Query: 145 SEASYLNSLNVLESQFVAHPAFRDPHI 171
+ AS+LN N L S H A R P +
Sbjct: 69 ANASHLNGHNTLYSNVRPHAALRGPAV 95
>UniRef50_A1WDB2 Cluster: Putative uncharacterized protein
precursor; n=1; Acidovorax sp. JS42|Rep: Putative
uncharacterized protein precursor - Acidovorax sp.
(strain JS42)
Length = 279
Score = 34.7 bits (76), Expect = 2.3
Identities = 21/71 (29%), Positives = 32/71 (45%), Gaps = 2/71 (2%)
Query: 64 VESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLC 123
V ++Y T D S G + P AQAP P+ + A ++S G R S+ ++ P
Sbjct: 134 VTAVYWRTNDQISTGVQVRTPAAQAPAPQASATPASPIIS--GTPRPAAAASQGAALPSR 191
Query: 124 SVSSLAPAQKR 134
+ PA R
Sbjct: 192 PAPLVPPAPAR 202
>UniRef50_A7SRN5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1253
Score = 34.7 bits (76), Expect = 2.3
Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
ELL +E +Y+ L V+ F P +LP ++LFSTI P+ ++ELE+
Sbjct: 704 ELLNTERTYVKDLEVITIAF--REVVSSPGVLPEATKKLLFSTIDPIYDFHCAFLSELEE 761
>UniRef50_A7RXM0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 2056
Score = 34.7 bits (76), Expect = 2.3
Identities = 19/65 (29%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 84 PGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELL 143
P + APPP+P+ SA + + P + SSTP S+++P+Q Q+ F+ +
Sbjct: 466 PPSVAPPPQPS--SAPTVAQMQQPQQPWTYPQSESSTPANQSSTVSPSQSMPQQQSFQSV 523
Query: 144 TSEAS 148
++ S
Sbjct: 524 SNSPS 528
>UniRef50_A4HKE4 Cluster: Putative uncharacterized protein; n=1;
Leishmania braziliensis|Rep: Putative uncharacterized
protein - Leishmania braziliensis
Length = 736
Score = 34.7 bits (76), Expect = 2.3
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
Query: 65 ESIYRETGDSDSDGYEAGVPGAQAPPPEPAR--PSAMALVSP-RGPARTLWCESRRSSTP 121
+ + R + DG + G G++ P PEPAR P+ ++ P GPA T R +
Sbjct: 452 QDVERIRNAAHHDGKQHG-HGSE-PLPEPARQLPTQQPVLRPAHGPAGTFVLSDRHEA-- 507
Query: 122 LCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRD 168
C+ + +AP R QE + T+E + S V +S V P+ +D
Sbjct: 508 -CASTPVAPLLLRSQEPMMPITTTEPALAASTLVEQSTHVI-PSVKD 552
>UniRef50_A2EKU3 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 1089
Score = 34.7 bits (76), Expect = 2.3
Identities = 25/94 (26%), Positives = 48/94 (51%), Gaps = 5/94 (5%)
Query: 142 LLTSEASYLN--SLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELE 199
LL S++S + S ++++ F +P +IL ++ I+ ++L++ +
Sbjct: 578 LLDSQSSIVRKRSKDLIKKLFETNPILTFSNILIQNLMNENIQKIVNKMNLTELIVEKTI 637
Query: 200 KCWQENILLQGI--CDIVRHHAEEHFQVYVKYCE 231
+QEN+ L+G+ D + H EE F V KYC+
Sbjct: 638 DTFQENVTLEGVKTVDFISTHYEE-FAVKYKYCD 670
>UniRef50_Q504U0 Cluster: LOC201725 protein; n=9; Theria|Rep:
LOC201725 protein - Homo sapiens (Human)
Length = 113
Score = 34.7 bits (76), Expect = 2.3
Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 89 PPPEPARPS---AMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQEAKFELL-T 144
PPP P+ PS A A SP GP W RSS P +V L + ++ +A F L
Sbjct: 13 PPPPPSSPSSSDASAASSPGGPVSLGWPVPSRSSGP--TVDQLEEVELQIGDAAFSLTKL 70
Query: 145 SEASYLNSLNVLESQF 160
EA+ S V E F
Sbjct: 71 LEATSAVSAQVEELAF 86
>UniRef50_A4R505 Cluster: Predicted protein; n=1; Magnaporthe
grisea|Rep: Predicted protein - Magnaporthe grisea (Rice
blast fungus) (Pyricularia grisea)
Length = 987
Score = 34.7 bits (76), Expect = 2.3
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 4/80 (5%)
Query: 68 YRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLW--CESRRS--STPLC 123
Y G++ + G E + P S ++V+PRG A ++W CE R+S S P
Sbjct: 805 YLSLGEAVASGEETEAAPQNSHLSSPPHSSPSSVVTPRGCAMSIWGGCEDRQSSCSPPAA 864
Query: 124 SVSSLAPAQKRLQEAKFELL 143
SS+ +L + K L
Sbjct: 865 QRSSVEDMDDQLMQLKMPKL 884
>UniRef50_UPI0000F2B1C8 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 201
Score = 34.3 bits (75), Expect = 3.1
Identities = 16/34 (47%), Positives = 18/34 (52%), Gaps = 2/34 (5%)
Query: 85 GAQAPPPEPARPSAMALVSPRGPARTLWCESRRS 118
GA AP P P P + L P GP R W +RRS
Sbjct: 65 GASAPAPPPRTPPLVPL--PPGPGRVAWASARRS 96
>UniRef50_UPI0000E47DAB Cluster: PREDICTED: similar to epithelial cell
transforming sequence 2 oncogene; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to epithelial cell
transforming sequence 2 oncogene - Strongylocentrotus
purpuratus
Length = 1305
Score = 34.3 bits (75), Expect = 3.1
Identities = 29/123 (23%), Positives = 58/123 (47%), Gaps = 11/123 (8%)
Query: 141 ELLTSEASYLNSLNVLESQFVAH--PAFRDPH-ILPRDDWEILFSTILPVRKCSQLLMNE 197
E+L SE YL LN++ + + A R H I+ + + ++F+ + ++ L E
Sbjct: 971 EILDSERVYLRRLNIIHNVYFERLAAALRSNHAIIGQTNISLIFTDTNNILNVTRGLFEE 1030
Query: 198 LE---KCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRER-PAFATAL 253
L+ + W + L G C I + + Y + N +++ + + RE+ P+F L
Sbjct: 1031 LKGRVESWSVQMCL-GDCFI---KFQSKLKAYTNFHNNYAIVLSTIDKCREQEPSFRAFL 1086
Query: 254 KRY 256
K++
Sbjct: 1087 KQH 1089
>UniRef50_UPI000051A437 Cluster: PREDICTED: similar to RhoGEF4
CG8606-PA, isoform A; n=1; Apis mellifera|Rep:
PREDICTED: similar to RhoGEF4 CG8606-PA, isoform A -
Apis mellifera
Length = 465
Score = 34.3 bits (75), Expect = 3.1
Identities = 40/147 (27%), Positives = 64/147 (43%), Gaps = 13/147 (8%)
Query: 103 SPRGPARTLWCESRR---SSTPLCSVSSLAPAQKRLQ-EAKFELLTSEASYLNSLNVLES 158
SPR P L CE ++ L S + +K L+ +A E+LT+E +YL L +L
Sbjct: 3 SPRSPQTPLSCELKKIINDRNILSMRSRMKEKEKNLRFQAIQEILTTEVTYLRQLEILME 62
Query: 159 QFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHH 218
F+ P F + +L + L I + S L+ EL++ Q I D H
Sbjct: 63 YFI-QPMF-EKKLLNYNLLSTLSENIKTLYNVSGELIQELKED------PQNIADAF-HK 113
Query: 219 AEEHFQVYVKYCENQTLMVKALQRLRE 245
F++Y Y + ++ LQ +E
Sbjct: 114 LAPFFKLYSIYAYDYEQILLLLQNKQE 140
>UniRef50_UPI000065F563 Cluster: Homolog of Brachydanio rerio
"Quattro.; n=1; Takifugu rubripes|Rep: Homolog of
Brachydanio rerio "Quattro. - Takifugu rubripes
Length = 1628
Score = 34.3 bits (75), Expect = 3.1
Identities = 34/120 (28%), Positives = 54/120 (45%), Gaps = 7/120 (5%)
Query: 117 RSSTPLCSVSSLAPAQK--RLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPR 174
R+ TP S SS +LQ+ ELLT+E Y+++L + + D R
Sbjct: 1266 RALTPETSPSSTGNISNNLKLQKIMEELLTTEREYVSALGYVRDHYFPELERADVPQDLR 1325
Query: 175 DDWEILFSTILPVRKCSQ-LLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQ 233
I+F + + Q ++ELE C E + G C ++RH E F +Y Y +N+
Sbjct: 1326 GQRGIIFGNLEKLHDFHQHHFLSELEGCVNEPFRV-GRC-VLRH--VESFALYALYSKNK 1381
>UniRef50_Q6CSA4 Cluster: Similar to sgd|S0004417 Saccharomyces
cerevisiae YLR425w TUS1; n=1; Kluyveromyces lactis|Rep:
Similar to sgd|S0004417 Saccharomyces cerevisiae YLR425w
TUS1 - Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 1328
Score = 34.3 bits (75), Expect = 3.1
Identities = 34/136 (25%), Positives = 62/136 (45%), Gaps = 8/136 (5%)
Query: 125 VSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDD--WEILFS 182
+S + P + + Q F+L+ E SLN+ + + A DP +LP D + +
Sbjct: 491 LSEINPKEVKRQSFIFDLIVLEE---RSLNLANAAVEIYGASFDPALLPDDPNFKSMAYD 547
Query: 183 TILPVRKCSQ--LLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKAL 240
+P+ + + LL L K + + G+ I A + QVYVKY +N + + +
Sbjct: 548 IFIPLIELHKDILLSPILWKLKIKGKFIDGVGKIYLKWANDAKQVYVKYAQNMATVHEII 607
Query: 241 QRLRE-RPAFATALKR 255
+E FA+ L++
Sbjct: 608 NWEKENNTRFASWLRQ 623
>UniRef50_Q6DEY6 Cluster: MGC89379 protein; n=2; Xenopus|Rep:
MGC89379 protein - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 384
Score = 33.9 bits (74), Expect = 4.0
Identities = 29/127 (22%), Positives = 52/127 (40%), Gaps = 2/127 (1%)
Query: 75 DSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLC-SVSSLAPAQK 133
D GY + A PP P + VS A++ S+ SST + SV S A+K
Sbjct: 69 DVYGYNSTTADAPPPPVSKCPPKNASTVSAPSKAQSKSTVSKASSTSVAISVHSHRAAKK 128
Query: 134 RLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQL 193
E+ LL + + + A P+ P + P ++ ++P+ + +
Sbjct: 129 DSSESSTNLLLQSLNQ-EKTDQSDVSATAFPSSMYPGVYPAMRLSVVLEALVPLNETASS 187
Query: 194 LMNELEK 200
L ++L +
Sbjct: 188 LESKLNQ 194
>UniRef50_A5NRC7 Cluster: Putative uncharacterized protein; n=1;
Methylobacterium sp. 4-46|Rep: Putative uncharacterized
protein - Methylobacterium sp. 4-46
Length = 444
Score = 33.9 bits (74), Expect = 4.0
Identities = 25/81 (30%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 64 VESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSP-----RGPARTLWCESRRS 118
++ + E D D AG P A PPP A P A A+ +P RG AR RR
Sbjct: 339 LDLVLAEPSTPDRDPPPAGAPVALLPPPSSATPVADAVAAPVATSSRGQARPARRPRRRP 398
Query: 119 STPLCSVSSLAPAQKRLQEAK 139
+ + + SS A + + K
Sbjct: 399 TESVTAPSSSTAAVRLARRPK 419
>UniRef50_A0X5W0 Cluster: Putative uncharacterized protein; n=2;
Shewanella|Rep: Putative uncharacterized protein -
Shewanella pealeana ATCC 700345
Length = 587
Score = 33.9 bits (74), Expect = 4.0
Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 162 AHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEE 221
AH D IL E F P+ ++L E C+ ++ LL IC+I+R +
Sbjct: 192 AHFCVNDSQILALSSIEKPFIKARPISSHTRLKQPIYELCFAKSRLLLVICEIMRQQGID 251
Query: 222 HFQVYVKYCENQTL-MVKALQRLRERPAFATAL 253
+ VY+ +N + MV+A L + P+ A L
Sbjct: 252 Y--VYIANSQNPKIAMVEAKWSLIDTPSSAQKL 282
>UniRef50_A7RLP1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 1145
Score = 33.9 bits (74), Expect = 4.0
Identities = 19/41 (46%), Positives = 22/41 (53%)
Query: 81 AGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTP 121
A VP A AP P PA PSA A +P + S RS+TP
Sbjct: 192 APVPAAAAPAPAPAAPSAAAAPAPVRSVPSTSPSSVRSATP 232
>UniRef50_Q0UHK2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 687
Score = 33.9 bits (74), Expect = 4.0
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 63 KVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPL 122
++E +RE D D E+ G+QA P E R +M +VS R AR L + R + P
Sbjct: 270 EIEDTFREVIVLDDDDDESSDAGSQATPDE--REQSMEIVSSRATARDL--QPERYAGPR 325
Query: 123 CSVSSLAPAQKR 134
+ + A +R
Sbjct: 326 MDIHGMRRAPRR 337
>UniRef50_Q96SB4 Cluster: Serine/threonine-protein kinase SRPK1;
n=56; Euteleostomi|Rep: Serine/threonine-protein kinase
SRPK1 - Homo sapiens (Human)
Length = 826
Score = 33.9 bits (74), Expect = 4.0
Identities = 31/89 (34%), Positives = 37/89 (41%), Gaps = 6/89 (6%)
Query: 85 GAQAPPPEPARPSAMALVSPRGPARTLWCES-RRSSTPLCSVSSLAPAQKRLQEAKFELL 143
G + PP PARP P PAR L C S TP S S P ++ Q LL
Sbjct: 94 GGRRRPP-PARPLTRPETPPAHPARALLCAPWAASPTPAASPSPQPPPRQAPQPGLAPLL 152
Query: 144 TSEASYLNSLNVLESQFVAHPAFRDPHIL 172
+L L L S F HP+ P +L
Sbjct: 153 GLH-PHLGRL--LSSTFALHPSL-SPAVL 177
>UniRef50_UPI0000E1E614 Cluster: PREDICTED: similar to novel PH
domain-containing protein; n=1; Pan troglodytes|Rep:
PREDICTED: similar to novel PH domain-containing protein
- Pan troglodytes
Length = 811
Score = 33.5 bits (73), Expect = 5.4
Identities = 42/141 (29%), Positives = 65/141 (46%), Gaps = 13/141 (9%)
Query: 128 LAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPA-FRDPHILPRDDWEILFSTI-- 184
L Q QEA +ELL +EASY+ L V+ + F+ ++ +L + E LFS I
Sbjct: 308 LTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPE 367
Query: 185 ---LPVRKCSQLLMNELEKCWQENILLQGICDIVRHHA--EEHFQVYVKYC-ENQTLMVK 238
L R + ++ LEK + LLQ D ++ F+ Y++YC E + M
Sbjct: 368 IAQLHRRLWASVMAPVLEKARRTRALLQP-GDFLKGFKMFGSLFKPYIRYCMEEEGCMEY 426
Query: 239 ALQRLRERP---AFATALKRY 256
LR+ A+ T LK +
Sbjct: 427 MRGLLRDNDLFRAYITLLKEF 447
>UniRef50_UPI00005A1291 Cluster: PREDICTED: hypothetical protein
XP_863639; n=1; Canis lupus familiaris|Rep: PREDICTED:
hypothetical protein XP_863639 - Canis familiaris
Length = 208
Score = 33.5 bits (73), Expect = 5.4
Identities = 22/54 (40%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 87 QAPPPEPARPSAMALV-SPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQEAK 139
+AP P PAR L +P G + E+RRS+ P +VS+ P LQEAK
Sbjct: 76 RAPAPGPARWGYSRLSGTPGGAFLSAASEARRSAAPRPAVSAGGPGAAPLQEAK 129
>UniRef50_Q0YHU8 Cluster: Hemerythrin HHE cation binding region;
n=1; Geobacter sp. FRC-32|Rep: Hemerythrin HHE cation
binding region - Geobacter sp. FRC-32
Length = 187
Score = 33.5 bits (73), Expect = 5.4
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 12/113 (10%)
Query: 149 YLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEKC------W 202
++ N L++ F F P +LP D + L L + ++ L+ +LEK W
Sbjct: 54 FITLRNELQAHFQIEEKFFYPKLLPIQDMKALVEDALDEHQEAKDLLLQLEKIGFGAEDW 113
Query: 203 QENILLQGICDIVRHHAE----EHFQVYVKYCENQTLMVKALQRLRERPAFAT 251
QE + D +RHH E E F ++ ++Q L A + ++E+ F T
Sbjct: 114 QET--FSKLEDGIRHHHEDEEQEIFPKCTQFLKDQDLTDMARKSVQEKEHFLT 164
>UniRef50_A6NVZ6 Cluster: Single-stranded DNA-binding protein; n=1;
Bacteroides capillosus ATCC 29799|Rep: Single-stranded
DNA-binding protein - Bacteroides capillosus ATCC 29799
Length = 161
Score = 33.5 bits (73), Expect = 5.4
Identities = 19/39 (48%), Positives = 23/39 (58%), Gaps = 5/39 (12%)
Query: 73 DSDSDGYEA---GVPGAQAPPPEPARPSAMALVSPRGPA 108
D+++ GY A G G APPP PA PS M +P GPA
Sbjct: 109 DAEAGGYSAPSYGAQGGYAPPPAPA-PS-MGYAAPAGPA 145
>UniRef50_A1U9Z9 Cluster: Putative uncharacterized protein; n=6;
Mycobacterium|Rep: Putative uncharacterized protein -
Mycobacterium sp. (strain KMS)
Length = 603
Score = 33.5 bits (73), Expect = 5.4
Identities = 19/44 (43%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 69 RETGDSDSDGYEAG-VPGAQAPPPEPARPSAMALVSPRGPARTL 111
R T D EA VP AQAP P PA + A+ P PA T+
Sbjct: 345 RPTADQRPSPAEAAIVPSAQAPRPAPAPEAQPAVAPPAPPAETI 388
>UniRef50_A1GG63 Cluster: DNA polymerase III, subunits gamma and
tau; n=2; Salinispora|Rep: DNA polymerase III, subunits
gamma and tau - Salinispora arenicola CNS205
Length = 888
Score = 33.5 bits (73), Expect = 5.4
Identities = 27/76 (35%), Positives = 35/76 (46%), Gaps = 6/76 (7%)
Query: 60 NAAKVESIYRETGD--SDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRR 117
+ A VE TG +DS +G P A+ PEPARP A P G A W E+ R
Sbjct: 678 STAPVEPARSPTGGGVADSGSRRSGGPAAEEEWPEPARPGG-AASEPVGSAAGDWPETAR 736
Query: 118 ---SSTPLCSVSSLAP 130
S+T + S+ P
Sbjct: 737 PGASATAPAAPSAAGP 752
>UniRef50_Q4Q5W0 Cluster: Putative uncharacterized protein; n=3;
Leishmania|Rep: Putative uncharacterized protein -
Leishmania major
Length = 987
Score = 33.5 bits (73), Expect = 5.4
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 73 DSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLA 129
D DSD E G P P +P+ S A SP G A T +RSS+ +SSLA
Sbjct: 866 DDDSDNEEVGKP--VPPSAQPSTSSPSAADSPPGAAATSSAADQRSSS-TAGISSLA 919
>UniRef50_Q29J41 Cluster: GA15289-PA; n=1; Drosophila
pseudoobscura|Rep: GA15289-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 1008
Score = 33.5 bits (73), Expect = 5.4
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 5/60 (8%)
Query: 80 EAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQEAK 139
E PGA A PP+ RP+A + + + + R P SS APA+K+L AK
Sbjct: 718 EKEAPGAGAAPPQKQRPAAGS-----HERKVISLKRREDQDPAGETSSAAPARKQLTAAK 772
>UniRef50_A2F8H3 Cluster: Kelch motif family protein; n=1;
Trichomonas vaginalis G3|Rep: Kelch motif family protein
- Trichomonas vaginalis G3
Length = 1055
Score = 33.5 bits (73), Expect = 5.4
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
E++ +E SY+NSL +LE + PAF+ I + LF I + K + +L+K
Sbjct: 189 EIVKTEESYVNSLKMLEDYW--QPAFKKAKIFEESELHKLFREIKGIYKVHSDFLEDLKK 246
>UniRef50_Q4P9T6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1330
Score = 33.5 bits (73), Expect = 5.4
Identities = 23/95 (24%), Positives = 39/95 (41%)
Query: 69 RETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSL 128
R G+ S + APP P++PS ++ +P L S S++P+ S +
Sbjct: 452 RNLGEWGSSYWPQAASPPAAPPFAPSQPSLLSQSAPHSAPHPLRQASSASTSPMLSAADA 511
Query: 129 APAQKRLQEAKFELLTSEASYLNSLNVLESQFVAH 163
A KRL L A+ + ++S +H
Sbjct: 512 GRAAKRLSTGATALADVAAAAAATAASVQSAHNSH 546
>UniRef50_Q70EK9 Cluster: Ubiquitin carboxyl-terminal hydrolase 51;
n=66; Deuterostomia|Rep: Ubiquitin carboxyl-terminal
hydrolase 51 - Homo sapiens (Human)
Length = 711
Score = 33.5 bits (73), Expect = 5.4
Identities = 18/39 (46%), Positives = 18/39 (46%), Gaps = 1/39 (2%)
Query: 84 PGAQAPPPEPAR-PSAMALVSPRGPARTLWCESRRSSTP 121
PG APPP PAR P P P W SRR S P
Sbjct: 118 PGLSAPPPPPARPPPPPPPPPPPAPRPRAWRGSRRRSRP 156
>UniRef50_Q96M96 Cluster: FYVE, RhoGEF and PH domain-containing
protein 4; n=34; Amniota|Rep: FYVE, RhoGEF and PH
domain-containing protein 4 - Homo sapiens (Human)
Length = 766
Score = 33.5 bits (73), Expect = 5.4
Identities = 32/126 (25%), Positives = 62/126 (49%), Gaps = 4/126 (3%)
Query: 132 QKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFR-DPHILPRDDWEILFSTILPVRKC 190
+++L + ELL +E +Y+N L++L+ F + P + +FS I +
Sbjct: 204 EQKLHKIANELLLTERAYVNRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAF 263
Query: 191 -SQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRER-PA 248
S+ L+ ELEK QE I DI++ A ++Y +Y + ++ ++ + ER P
Sbjct: 264 HSKFLLPELEKRMQEWETTPRIGDILQKLA-PFLKMYGEYVKGFDNAMELVKNMTERIPQ 322
Query: 249 FATALK 254
F + ++
Sbjct: 323 FKSVVE 328
>UniRef50_UPI0000F2E5C5 Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 250
Score = 33.1 bits (72), Expect = 7.1
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 1/56 (1%)
Query: 76 SDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPA 131
S +EA + PPP PARPS + SP P E + P C + PA
Sbjct: 49 SFSHEAQEANGEPPPPPPARPSCSSCRSPSAPTHA-GPEGGQVRAPRCLPGTQRPA 103
>UniRef50_UPI0000D55A08 Cluster: PREDICTED: similar to intersectin 1;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
intersectin 1 - Tribolium castaneum
Length = 1577
Score = 33.1 bits (72), Expect = 7.1
Identities = 27/126 (21%), Positives = 57/126 (45%), Gaps = 7/126 (5%)
Query: 120 TPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEI 179
TPL S++ K+ Q++ E + +E Y++ + + F + ++ RD+ E
Sbjct: 1072 TPLQQQSTVV--NKKRQDSIREFIQTEKVYVDDMTTVHEVFEL--PMKKSGVIGRDEVEK 1127
Query: 180 LFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKA 239
+F + +C++ +++L + G ++ H + + QVY +C Q
Sbjct: 1128 IFLNWQAILQCNRRFLSDLYDWTSSGSDILG--PVISKHLQ-NMQVYEVFCGKQLDSAAL 1184
Query: 240 LQRLRE 245
LQ+L E
Sbjct: 1185 LQKLTE 1190
>UniRef50_UPI00006C09CB Cluster: PREDICTED: hypothetical protein;
n=1; Homo sapiens|Rep: PREDICTED: hypothetical protein -
Homo sapiens
Length = 257
Score = 33.1 bits (72), Expect = 7.1
Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 2/40 (5%)
Query: 70 ETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPR-GPA 108
E D+ + G PG + PPP PARP A AL+ P GPA
Sbjct: 147 EVRPQDAQRGDPGRPGRR-PPPLPARPPAPALLCPSPGPA 185
>UniRef50_UPI00015A5797 Cluster: UPI00015A5797 related cluster; n=1;
Danio rerio|Rep: UPI00015A5797 UniRef100 entry - Danio
rerio
Length = 1772
Score = 33.1 bits (72), Expect = 7.1
Identities = 32/116 (27%), Positives = 52/116 (44%), Gaps = 11/116 (9%)
Query: 122 LCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRD---DWE 178
LCS+ + A ++LQ ELL +E Y+ SL + + + +P P + P+D
Sbjct: 1384 LCSIHKILSAVQKLQRIMEELLLTEVEYVRSLGYILTHY--YPLLSRPDV-PQDLRGQRG 1440
Query: 179 ILFSTILPVRKC-SQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQ 233
+F + + Q EL+ C Q L G C + H E F +Y Y +N+
Sbjct: 1441 RIFGNLEKLYDFHCQHFQQELQAC-QAEPLRAGRC-FLNH--RESFGLYALYSKNK 1492
>UniRef50_Q4SEW8 Cluster: Chromosome undetermined SCAF14611, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14611, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1152
Score = 33.1 bits (72), Expect = 7.1
Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 9/114 (7%)
Query: 124 SVSSLAPAQK--RLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRD-PHILPRDDWEIL 180
S S AP + +L+ E++T+E Y+ SL+ + + D P L R ++
Sbjct: 662 SSSPAAPQHRGGKLRHIVEEMVTTEREYVRSLHYIIHHYFPEMERADLPQDL-RGKRSVV 720
Query: 181 FSTILPVRKC-SQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQ 233
F + + SQ + ELE CW+ L+ +RH +E F +Y Y +N+
Sbjct: 721 FGNLEKLLDFHSQYFLKELEACWKHP--LRAPHCFLRH--QEQFGLYALYSKNK 770
>UniRef50_Q4SDF0 Cluster: Chromosome 3 SCAF14639, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14639, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1655
Score = 33.1 bits (72), Expect = 7.1
Identities = 30/141 (21%), Positives = 56/141 (39%), Gaps = 6/141 (4%)
Query: 70 ETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSP-RGPARTLWCESRRSSTPLCSVSSL 128
E G +G++ G+PG P EP +P ++ L G L R + L +
Sbjct: 712 EQGPQGLNGFQ-GLPGLPGNPGEPGKPGSVCLFQGLSGEVGLLGASGPRVGSDLTLILFQ 770
Query: 129 APAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILP-RDDWEILFSTILPV 187
+P+ Q F LL + + ++ V +DP ++P D +L + ++ +
Sbjct: 771 SPSN---QSTSFILLFVSPNRESEAHLEREVKVGPQVCKDPKVVPVHQDQMVLRAKLVYL 827
Query: 188 RKCSQLLMNELEKCWQENILL 208
L + +C + LL
Sbjct: 828 VLLENLEFQDFRECQEREALL 848
>UniRef50_Q4G5V0 Cluster: Reticulon 6-a1; n=22; Danio rerio|Rep:
Reticulon 6-a1 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 875
Score = 33.1 bits (72), Expect = 7.1
Identities = 39/130 (30%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 53 EPLYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLW 112
EP+ + +A + T S+ E VP PPP P P A +P P R+L
Sbjct: 243 EPITEITSAEQTSEETSLTQISEDVTEETSVPPVSGPPPPP--PHHPAAAAP-PPDRSLA 299
Query: 113 -CESRRSSTPLCSVSSLAPA-QKRLQEAKFELLTSE--ASYLNSLNVLESQFVAHP-AFR 167
C +R S L PA + + + F+ L SE S ++S + F P A
Sbjct: 300 PCNARPPEPCGEPHSELPPAGEPEVSVSVFQTLPSERCRSLVSSAGLAMDAFGREPSATS 359
Query: 168 DPHIL-PRDD 176
DP +L P DD
Sbjct: 360 DPDLLSPSDD 369
>UniRef50_Q3J4T6 Cluster: ThiF family protein; n=1; Rhodobacter
sphaeroides 2.4.1|Rep: ThiF family protein - Rhodobacter
sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 /
DSM158)
Length = 601
Score = 33.1 bits (72), Expect = 7.1
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 91 PEPARPSAMALVSPRGPARTL--WCESRRS--STPLCSVSSLAPAQKRLQEAKFELLTSE 146
P+ P L GP L W E RR S PL + +++P Q E+++ L+ S
Sbjct: 10 PDVLHPVTSLLRIGVGPVTALEGWKEWRRGFFSLPLVARVTISPGQSFPAESRWHLVVSS 69
Query: 147 ASYLNSLNVLESQFVAHPAFRDPH 170
SY + +L + VA P PH
Sbjct: 70 GSYPADIFILPDK-VAGPNLTFPH 92
>UniRef50_Q0RGB0 Cluster: ABC-type dipeptide/oligopeptide/nickel
transport systems, permease component; n=2;
Actinomycetales|Rep: ABC-type
dipeptide/oligopeptide/nickel transport systems,
permease component - Frankia alni (strain ACN14a)
Length = 350
Score = 33.1 bits (72), Expect = 7.1
Identities = 16/32 (50%), Positives = 18/32 (56%)
Query: 69 RETGDSDSDGYEAGVPGAQAPPPEPARPSAMA 100
RE +DSDG P A APP PA P+A A
Sbjct: 279 RERPAADSDGAPHAAPAAPAPPAAPAPPAAPA 310
>UniRef50_A3RV13 Cluster: Putative uncharacterized protein; n=1;
Ralstonia solanacearum UW551|Rep: Putative
uncharacterized protein - Ralstonia solanacearum UW551
Length = 561
Score = 33.1 bits (72), Expect = 7.1
Identities = 21/58 (36%), Positives = 32/58 (55%), Gaps = 5/58 (8%)
Query: 76 SDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSL-APAQ 132
S +++ V A AP P+PA+PS VSP+G + T +R +T ++ APAQ
Sbjct: 320 SGRFQSAVKRAPAPAPQPAKPS----VSPQGRSGTAAVRNRPPATAAAPARTVSAPAQ 373
>UniRef50_Q960G3 Cluster: SD03094p; n=2; Drosophila melanogaster|Rep:
SD03094p - Drosophila melanogaster (Fruit fly)
Length = 1838
Score = 33.1 bits (72), Expect = 7.1
Identities = 25/96 (26%), Positives = 39/96 (40%), Gaps = 1/96 (1%)
Query: 78 GYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKRLQE 137
GY V Q P P P S ++ G + T ++ S P S ++L + + E
Sbjct: 1298 GYLGSVNPQQQPTPAPPSNSNASIYMQSGASSTAETQTTSSGVPYASSAALTKVEPK-PE 1356
Query: 138 AKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILP 173
A +TS L+ L++ S V P P + P
Sbjct: 1357 ALPPKVTSNVDLLSDLDIDCSVAVPPPMLPQPVLQP 1392
>UniRef50_Q6Q427 Cluster: Guanine nucleotide exchange factor; n=4;
Entamoeba|Rep: Guanine nucleotide exchange factor -
Entamoeba dispar
Length = 571
Score = 33.1 bits (72), Expect = 7.1
Identities = 24/97 (24%), Positives = 44/97 (45%), Gaps = 10/97 (10%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
E + +E +Y N +N+ + R ++L +++ I+F I+ + K NELEK
Sbjct: 256 EFIQTETNYTNQMNICCRIVIK----RLDNVL-KENLSIIFGNIIDIEKYHHKFSNELEK 310
Query: 201 CW----QENILLQGICDI-VRHHAEEHFQVYVKYCEN 232
C +E + DI +++ +Y KY N
Sbjct: 311 CLSLCNEEKLEFISFSDILLKYFTPSMLDLYCKYANN 347
>UniRef50_A5KAR9 Cluster: Variable surface protein Vir 12, putative;
n=1; Plasmodium vivax|Rep: Variable surface protein Vir
12, putative - Plasmodium vivax
Length = 508
Score = 33.1 bits (72), Expect = 7.1
Identities = 16/39 (41%), Positives = 24/39 (61%), Gaps = 1/39 (2%)
Query: 72 GDSDSDGYEAGVPGAQAPPPEPARPSAMA-LVSPRGPAR 109
G ++S+G E+G+P A P PA+P A + S R PA+
Sbjct: 241 GAAESEGAESGIPKPAAAKPAPAKPVATSPAPSERAPAK 279
>UniRef50_Q2H9P4 Cluster: Predicted protein; n=1; Chaetomium
globosum|Rep: Predicted protein - Chaetomium globosum
(Soil fungus)
Length = 210
Score = 33.1 bits (72), Expect = 7.1
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 3/71 (4%)
Query: 75 DSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKR 134
D Y GVPG P RPS A VS + WC RS L S ++A R
Sbjct: 120 DGIDYLNGVPGR---PWHNPRPSTCARVSCSYGSAIYWCNDNRSRKELNSYQNIAHGADR 176
Query: 135 LQEAKFELLTS 145
++ E+ S
Sbjct: 177 IKNTCHEIFPS 187
>UniRef50_P53046 Cluster: RHO1 GDP-GTP exchange protein 1; n=3;
Saccharomyces cerevisiae|Rep: RHO1 GDP-GTP exchange
protein 1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 1155
Score = 33.1 bits (72), Expect = 7.1
Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 118 SSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRD 175
+S P SL+ Q + QEA +EL T+E ++ SL ++ F+ + +I+P D
Sbjct: 448 NSVPKSVWESLSKQQIKRQEAIYELFTTEKKFVKSLEIIRDTFM--KKLLETNIIPSD 503
>UniRef50_Q96NY7 Cluster: Chloride intracellular channel 6; n=111;
Coelomata|Rep: Chloride intracellular channel 6 - Homo
sapiens (Human)
Length = 704
Score = 33.1 bits (72), Expect = 7.1
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 5/72 (6%)
Query: 70 ETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLA 129
E GD DG EAGVP + E +M P G AR + E ++S SL+
Sbjct: 251 EAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQSGD-----GSLS 305
Query: 130 PAQKRLQEAKFE 141
P + ++ A E
Sbjct: 306 PQAEAIEVAAGE 317
>UniRef50_Q9NR80 Cluster: Rho guanine nucleotide exchange factor 4;
n=65; Euteleostomi|Rep: Rho guanine nucleotide exchange
factor 4 - Homo sapiens (Human)
Length = 657
Score = 33.1 bits (72), Expect = 7.1
Identities = 25/106 (23%), Positives = 46/106 (43%), Gaps = 7/106 (6%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
E+L++E Y+ L + +V R + + +F I + +C + + LE+
Sbjct: 258 EILSTERDYIKHLRDICEGYVRQCRKR-ADMFSEEQLRTIFGNIEDIYRCQKAFVKALEQ 316
Query: 201 CWQE---NILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRL 243
+ ++ G C + H A+ FQ+Y +YC N L RL
Sbjct: 317 RFNRERPHLSELGAC-FLEHQAD--FQIYSEYCNNHPNACVELSRL 359
>UniRef50_UPI00015B4CDD Cluster: PREDICTED: similar to pleckstrin
homology domain containing, family G (with RhoGef
domain) member 1; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to pleckstrin homology domain
containing, family G (with RhoGef domain) member 1 -
Nasonia vitripennis
Length = 1440
Score = 32.7 bits (71), Expect = 9.4
Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 6/126 (4%)
Query: 130 PAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRD-DWEILFSTILPVR 188
P + ++ E++ +EA Y+ L + ++ DP L RD + LFS I +
Sbjct: 229 PHRSPVERVLLEIVDTEAVYVEHLRQVIQGYLIFWR-DDPASLIRDLELNGLFSNIEDIF 287
Query: 189 KCSQLLMNELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPA 248
+ ++ ++ L+ + I + + H++ F+VY +YC N V L L +
Sbjct: 288 EFNRNFLSALDSSGLDPIAVANT--FIEHNSG--FKVYTEYCTNYPTTVSILTELMSQEV 343
Query: 249 FATALK 254
A A +
Sbjct: 344 IARAFR 349
>UniRef50_UPI0000F21464 Cluster: PREDICTED: hypothetical protein;
n=4; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 1223
Score = 32.7 bits (71), Expect = 9.4
Identities = 24/110 (21%), Positives = 48/110 (43%), Gaps = 3/110 (2%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
E++ +E Y+ L + ++ + P + + +FS I + + + + +LE+
Sbjct: 816 EIMDTERVYIKHLKDICEGYIRQ-CRKHPGMFTDTQLKTIFSNIEDIYRFQRKFLKDLER 874
Query: 201 CWQ-ENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPAF 249
+ EN L I EE F +Y +YC + LQRL ++ +
Sbjct: 875 KYNPENPHLSEIGSCFLQQ-EEGFSIYSEYCNTHPVACAELQRLMKQSRY 923
>UniRef50_UPI0000EBEEAA Cluster: PREDICTED: hypothetical protein;
n=1; Bos taurus|Rep: PREDICTED: hypothetical protein -
Bos taurus
Length = 312
Score = 32.7 bits (71), Expect = 9.4
Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 4/73 (5%)
Query: 59 YNAAKVESIY-RETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRR 117
++AA + S + R + +DG G+P PPP P RP A P G + R
Sbjct: 172 HSAAAILSPHTRSRSQTPADG---GLPAPTPPPPPPPRPPPAASPRPGGEGGPAPGKDRE 228
Query: 118 SSTPLCSVSSLAP 130
+ P S SS P
Sbjct: 229 QAAPPSSSSSPLP 241
>UniRef50_UPI0000EBC7F9 Cluster: PREDICTED: hypothetical protein;
n=1; Bos taurus|Rep: PREDICTED: hypothetical protein -
Bos taurus
Length = 236
Score = 32.7 bits (71), Expect = 9.4
Identities = 21/49 (42%), Positives = 25/49 (51%), Gaps = 3/49 (6%)
Query: 86 AQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPAQKR 134
AQ PP PAR A + R PAR S +STPL +V+S P R
Sbjct: 56 AQCPPAGPARLQQPAALGLRPPAR---ASSSPTSTPLQTVTSSTPPPPR 101
>UniRef50_UPI00005A02E9 Cluster: PREDICTED: similar to USP6
N-terminal like; n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to USP6 N-terminal like - Canis
familiaris
Length = 437
Score = 32.7 bits (71), Expect = 9.4
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 82 GVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPA 131
G+PG P R A ++P GPA W + +R P+ SS+APA
Sbjct: 196 GLPGMHPRPGAAVRREPCAFLAPPGPAGD-WTQPKR-PPPVAGASSVAPA 243
>UniRef50_UPI000049A432 Cluster: Rho guanine nucleotide exchange
factor; n=1; Entamoeba histolytica HM-1:IMSS|Rep: Rho
guanine nucleotide exchange factor - Entamoeba
histolytica HM-1:IMSS
Length = 452
Score = 32.7 bits (71), Expect = 9.4
Identities = 28/109 (25%), Positives = 49/109 (44%), Gaps = 3/109 (2%)
Query: 141 ELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQLLMNELEK 200
EL T+E +Y + L + + V + ++L ++D+E LF I V S LL +L+K
Sbjct: 10 ELATTEKTYSDMLQLAIN--VYFQPIQKSNVLDKNDFEQLFCNIETVAMNSMLLCYDLQK 67
Query: 201 CWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKALQRLRERPAF 249
ICD++ + F Y +Y N ++ +L + F
Sbjct: 68 REANFEQNDIICDVLLFR-KTLFDCYNEYIRNYDRAIERYGKLLNKKKF 115
>UniRef50_UPI0000DBF905 Cluster: UPI0000DBF905 related cluster; n=1;
Rattus norvegicus|Rep: UPI0000DBF905 UniRef100 entry -
Rattus norvegicus
Length = 1513
Score = 32.7 bits (71), Expect = 9.4
Identities = 15/38 (39%), Positives = 18/38 (47%), Gaps = 1/38 (2%)
Query: 70 ETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGP 107
E G G+ GVPG PP P P A+A+ P P
Sbjct: 1064 EVGQKGDQGHP-GVPGFMGPPGNPGPPQAVAITIPAEP 1100
>UniRef50_UPI0000EB3C20 Cluster: UPI0000EB3C20 related cluster; n=1;
Canis lupus familiaris|Rep: UPI0000EB3C20 UniRef100
entry - Canis familiaris
Length = 530
Score = 32.7 bits (71), Expect = 9.4
Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 82 GVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVSSLAPA 131
G+PG P R A ++P GPA W + +R P+ SS+APA
Sbjct: 37 GLPGMHPRPGAAVRREPCAFLAPPGPAGD-WTQPKR-PPPVAGASSVAPA 84
>UniRef50_Q4SB75 Cluster: Chromosome undetermined SCAF14677, whole
genome shotgun sequence; n=4; Euteleostomi|Rep:
Chromosome undetermined SCAF14677, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 1131
Score = 32.7 bits (71), Expect = 9.4
Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 49 LFTHEPLYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPE-PARPSAMALVSPRGP 107
L +HEP +Q A + + E G D AG PG +A P+ P P ++ + RG
Sbjct: 718 LRSHEPAHQQPRAPRRGGVSSEGGRRRRDVARAGAPGQRADRPDGPHLPGSLQRLHRRGE 777
Query: 108 AR 109
R
Sbjct: 778 GR 779
>UniRef50_Q7UWF8 Cluster: Putative uncharacterized protein; n=1;
Pirellula sp.|Rep: Putative uncharacterized protein -
Rhodopirellula baltica
Length = 717
Score = 32.7 bits (71), Expect = 9.4
Identities = 38/132 (28%), Positives = 61/132 (46%), Gaps = 15/132 (11%)
Query: 71 TGDSDSDGY-EAGVPGAQAPPPEPARPSAMALVSP-RGPARTLWCESRRS---STPLCSV 125
+G+S SDG +AG+PGA P E P+ + SP GPA L + + + P +
Sbjct: 255 SGNSSSDGMMDAGIPGADG-PDESGVPNDLMPRSPLDGPAAVLGRDQPNAGPVAKPPATE 313
Query: 126 SSLAPAQKRLQE-AKFELL------TSEASYLNSLNVLESQF--VAHPAFRDPHILPRDD 176
S+ P + E A+F++L +A ++ VLE +A F DP ++
Sbjct: 314 SAPDPVMELPPEFAQFQMLLEMPGQAPDAPPMSEAPVLEDVVLDIAAEEFVDPMLIATPP 373
Query: 177 WEILFSTILPVR 188
E+ T L +R
Sbjct: 374 EEVNIETALKMR 385
>UniRef50_Q1DAK9 Cluster: Putative uncharacterized protein; n=1;
Myxococcus xanthus DK 1622|Rep: Putative uncharacterized
protein - Myxococcus xanthus (strain DK 1622)
Length = 159
Score = 32.7 bits (71), Expect = 9.4
Identities = 22/92 (23%), Positives = 40/92 (43%)
Query: 59 YNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRS 118
+ A++ ++ R GD A + + A S + ++ R AR++W + R
Sbjct: 26 FTASRSSALMRSRGDESLFPATASLASSYASSSPSLSRSTVEGLTERLHARSMWFKGVRP 85
Query: 119 STPLCSVSSLAPAQKRLQEAKFELLTSEASYL 150
ST + + +P + +Q F T ASYL
Sbjct: 86 STLPEARKTPSPTAQHVQTMNFNAFTLTASYL 117
>UniRef50_A1VFT2 Cluster: Sensor protein; n=2; Desulfovibrio
vulgaris subsp. vulgaris|Rep: Sensor protein -
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Length = 667
Score = 32.7 bits (71), Expect = 9.4
Identities = 21/75 (28%), Positives = 35/75 (46%), Gaps = 1/75 (1%)
Query: 70 ETGDSDSDGYEAGVPGAQAPPPEPARPSAMALVSPRGPARTLWCESRRSSTPLCSVS-SL 128
ET ++ A P + A P ARP + +V RT+ C+ R +C+ +
Sbjct: 382 ETPAINTPSEHAQAPTSSATPASGARPLRVLVVDDDATGRTITCKMLRKRGHVCACAHDG 441
Query: 129 APAQKRLQEAKFELL 143
A A +RL +F+L+
Sbjct: 442 ATALQRLTADRFDLV 456
>UniRef50_Q25AC2 Cluster: H0522A01.8 protein; n=4; Oryza sativa|Rep:
H0522A01.8 protein - Oryza sativa (Rice)
Length = 874
Score = 32.7 bits (71), Expect = 9.4
Identities = 16/47 (34%), Positives = 23/47 (48%)
Query: 55 LYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPPPEPARPSAMAL 101
L+ + +K + Y + D DG PG +A PP P RP A+ L
Sbjct: 631 LFHLSHPSKSKKHYFFSSIGDDDGAWGSSPGDRAGPPLPVRPGALGL 677
>UniRef50_Q9UKW0 Cluster: T-cell lymphoma invasion and metastasis 2;
n=16; Amniota|Rep: T-cell lymphoma invasion and
metastasis 2 - Homo sapiens (Human)
Length = 1077
Score = 32.7 bits (71), Expect = 9.4
Identities = 32/133 (24%), Positives = 61/133 (45%), Gaps = 16/133 (12%)
Query: 134 RLQEAKFELLTSEASYLNSLNVLESQFVAHPAFRDPHILPRDDWEILFSTILPVRKCSQL 193
RL++ EL+ +E SY+ L+ L ++ ++ L +D+ E LF ++ + + ++
Sbjct: 475 RLRKVIQELVDTEKSYVKDLSCLFELYLE--PLQNETFLTQDEMESLFGSLPEMLEFQKV 532
Query: 194 LM-------------NELEKCWQENILLQGICDIVRHHAEEHFQVYVKYCENQTLMVKAL 240
+ N LE Q LL + ++A+ HF++Y +C N + K L
Sbjct: 533 FLETLEDGISASSDFNTLETPSQFRKLLFSLGGSFLYYAD-HFKLYSGFCANHIKVQKVL 591
Query: 241 QRLRERPAFATAL 253
+R + AF L
Sbjct: 592 ERAKTDKAFKAFL 604
>UniRef50_O94827 Cluster: Pleckstrin homology domain-containing
family G member 5; n=34; Euteleostomi|Rep: Pleckstrin
homology domain-containing family G member 5 - Homo
sapiens (Human)
Length = 1091
Score = 32.7 bits (71), Expect = 9.4
Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 10/131 (7%)
Query: 128 LAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPA-FRDPHILPRDDWEILFSTI-- 184
L Q QEA +ELL +EASY+ L V+ + F+ ++ +L + E LFS I
Sbjct: 415 LTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPE 474
Query: 185 ---LPVRKCSQLLMNELEKCWQENILLQGICDIVRHHA--EEHFQVYVKYC-ENQTLMVK 238
L R + ++ LEK + LLQ D ++ F+ Y++YC E + M
Sbjct: 475 IAQLHRRLWASVMAPVLEKARRTRALLQP-GDFLKGFKMFGSLFKPYIRYCMEEEGCMEY 533
Query: 239 ALQRLRERPAF 249
LR+ F
Sbjct: 534 MRGLLRDNDLF 544
>UniRef50_Q6FPQ7 Cluster: Similar to sp|P32521 Saccharomyces
cerevisiae YIR006c PAN1; n=1; Candida glabrata|Rep:
Similar to sp|P32521 Saccharomyces cerevisiae YIR006c
PAN1 - Candida glabrata (Yeast) (Torulopsis glabrata)
Length = 1374
Score = 32.7 bits (71), Expect = 9.4
Identities = 29/104 (27%), Positives = 43/104 (41%), Gaps = 5/104 (4%)
Query: 53 EPLYQFYNAAKVESIYRETGDSDSDGYEAGVPGAQAPP-PEPARPSAMALVSPRGPARTL 111
+ LY N A + ++ ++ G A VP APP P P S V+P PA T
Sbjct: 1196 DDLYSKPNTAPQTAPVLDSSNTPQPGMNASVPAPIAPPIPTPQASSPAVPVAPPIPAVT- 1254
Query: 112 WCESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNV 155
SS P+ S + +A A Q+ + A N+ +V
Sbjct: 1255 ---PSESSIPMTSNADVAGADHLDQDTDISGAAASADKQNTSHV 1295
>UniRef50_Q5KF15 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 1380
Score = 32.7 bits (71), Expect = 9.4
Identities = 31/148 (20%), Positives = 66/148 (44%), Gaps = 7/148 (4%)
Query: 114 ESRRSSTPLCSVSSLAPAQKRLQEAKFELLTSEASYLNSLNVLESQFVAHPAF--RDPH- 170
++R ++ P+ + +K+L EL+ +E SYL+ ++ L++ + +DP+
Sbjct: 109 DARGNTGPVWTAVKSDEMKKKLANVIEELVRTERSYLSRVHALKTAYADRLRLYSKDPNQ 168
Query: 171 -ILPRDDWEILFSTILPVRKCSQLLMNELEKCWQENILLQGICDIVRHHAE--EHFQVYV 227
++P + + +F+ I + S + +LE+ Q + D+ H + F Y
Sbjct: 169 QLIPPYEAKAMFANIELIVPASMTFLGDLEEMMQSGHAEDLVGDVCLKHFKILRTFDPYR 228
Query: 228 KYCENQTLMVKALQ-RLRERPAFATALK 254
Y Q K Q L++ F T ++
Sbjct: 229 TYLSKQDESQKLFQDSLKKFIGFGTFIE 256
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.133 0.405
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 261,159,932
Number of Sequences: 1657284
Number of extensions: 10525520
Number of successful extensions: 50824
Number of sequences better than 10.0: 133
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 50687
Number of HSP's gapped (non-prelim): 174
length of query: 256
length of database: 575,637,011
effective HSP length: 99
effective length of query: 157
effective length of database: 411,565,895
effective search space: 64615845515
effective search space used: 64615845515
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 71 (32.7 bits)
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