Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002750-TA|BGIBMGA002750-PA|IPR005475|Transketolase,
central region, IPR005476|Transketolase, C-terminal,
IPR009014|Transketolase, C-terminal-like
(351 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X57778-1|CAA40924.1| 359|Homo sapiens E-1 beta subunit of the p... 470 e-132
M54788-1|AAA60053.1| 359|Homo sapiens pyruvate dehydrogenase E1... 470 e-132
M34479-1|AAA36428.1| 359|Homo sapiens pyruvate dehydrogenase be... 470 e-132
M34056-1|AAA60054.1| 335|Homo sapiens PDHB protein. 470 e-132
M34055-1|AAA60233.1| 359|Homo sapiens PDHB protein. 470 e-132
CR541911-1|CAG46709.1| 359|Homo sapiens PDHB protein. 470 e-132
BC001924-1|AAH01924.1| 359|Homo sapiens pyruvate dehydrogenase ... 470 e-132
BC000439-1|AAH00439.1| 359|Homo sapiens pyruvate dehydrogenase ... 470 e-132
J03576-1|AAA88097.1| 359|Homo sapiens pyruvate dehydrogenase be... 470 e-132
D90086-1|BAA14123.1| 359|Homo sapiens pyruvate dehydrogenase be... 470 e-132
AB209241-1|BAD92478.1| 164|Homo sapiens Hypothetical protein DK... 229 8e-60
U50708-1|AAB16763.1| 392|Homo sapiens branched chain alpha-keto... 180 5e-45
M55575-1|AAA51812.1| 392|Homo sapiens branched chain alpha-keto... 180 5e-45
D90391-1|BAA14389.1| 392|Homo sapiens E-1-beta subunit of branc... 180 5e-45
BT020063-1|AAV38866.1| 392|Homo sapiens branched chain keto aci... 180 5e-45
BC040139-1|AAH40139.1| 392|Homo sapiens branched chain keto aci... 180 5e-45
AL391595-1|CAI15049.1| 392|Homo sapiens branched chain keto aci... 180 5e-45
AL049696-1|CAC36881.2| 392|Homo sapiens branched chain keto aci... 180 5e-45
X52446-1|CAA36685.1| 373|Homo sapiens protein ( Human mRNA for ... 179 2e-44
BC034481-1|AAH34481.1| 218|Homo sapiens BCKDHB protein protein. 78 5e-14
AL391595-2|CAI15050.1| 218|Homo sapiens branched chain keto aci... 78 5e-14
M19123-1|AAA60052.1| 56|Homo sapiens PDHB protein. 72 4e-12
Z49258-4|CAH69900.1| 540|Homo sapiens transketolase-like 1 prot... 59 2e-08
Z49258-1|CAH69899.1| 596|Homo sapiens transketolase-like 1 prot... 59 2e-08
BC025382-1|AAH25382.2| 596|Homo sapiens transketolase-like 1 pr... 59 2e-08
CR533560-1|CAG38591.1| 626|Homo sapiens DKFZP434L1717 protein. 58 5e-08
BC125101-1|AAI25102.1| 626|Homo sapiens transketolase-like 2 pr... 58 5e-08
BC028707-1|AAH28707.4| 626|Homo sapiens transketolase-like 2 pr... 58 5e-08
AK057537-1|BAB71524.1| 320|Homo sapiens protein ( Homo sapiens ... 58 5e-08
AK057325-1|BAB71427.1| 626|Homo sapiens protein ( Homo sapiens ... 58 5e-08
X91817-1|CAA62925.1| 557|Homo sapiens transketolase protein. 56 2e-07
Z49258-5|CAI39236.1| 146|Homo sapiens transketolase-like 1 prot... 55 3e-07
X67688-1|CAA47919.1| 623|Homo sapiens transketolase protein. 43 0.001
U55017-1|AAA98961.1| 623|Homo sapiens transketolase protein. 43 0.001
BC024026-1|AAH24026.2| 536|Homo sapiens TKT protein protein. 43 0.001
BC009970-1|AAH09970.1| 623|Homo sapiens transketolase (Wernicke... 43 0.001
BC008615-1|AAH08615.1| 395|Homo sapiens Similar to transketolas... 43 0.001
BC002433-1|AAH02433.1| 457|Homo sapiens TKT protein protein. 43 0.001
AK223614-1|BAD97334.1| 623|Homo sapiens transketolase variant p... 43 0.001
L12711-1|AAA61222.1| 623|Homo sapiens transketolase protein. 43 0.002
D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc prot... 31 4.6
D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc prot... 31 4.6
AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 dom... 31 4.6
AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 dom... 31 4.6
U51015-1|AAB09779.1| 46|Homo sapiens branched chain alpha-keto... 31 6.1
U14622-1|AAA21557.1| 63|Homo sapiens protein ( Human transketo... 31 6.1
BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 dom... 31 8.0
>X57778-1|CAA40924.1| 359|Homo sapiens E-1 beta subunit of the
pyruvate dehydrogenase complex protein.
Length = 359
Score = 470 bits (1159), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>M54788-1|AAA60053.1| 359|Homo sapiens pyruvate dehydrogenase
E1-beta subunit protein.
Length = 359
Score = 470 bits (1159), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAAVQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>M34479-1|AAA36428.1| 359|Homo sapiens pyruvate dehydrogenase
beta-subunit protein.
Length = 359
Score = 470 bits (1159), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>M34056-1|AAA60054.1| 335|Homo sapiens PDHB protein.
Length = 335
Score = 470 bits (1159), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 3 APAAVQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 62
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 63 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 122
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 123 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 182
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 183 GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 241
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 242 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 301
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 302 TGADVPMPYAKILE 315
>M34055-1|AAA60233.1| 359|Homo sapiens PDHB protein.
Length = 359
Score = 470 bits (1159), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAAVQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>CR541911-1|CAG46709.1| 359|Homo sapiens PDHB protein.
Length = 359
Score = 470 bits (1159), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>BC001924-1|AAH01924.1| 359|Homo sapiens pyruvate dehydrogenase
(lipoamide) beta protein.
Length = 359
Score = 470 bits (1159), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>BC000439-1|AAH00439.1| 359|Homo sapiens pyruvate dehydrogenase
(lipoamide) beta protein.
Length = 359
Score = 470 bits (1159), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>J03576-1|AAA88097.1| 359|Homo sapiens pyruvate dehydrogenase beta
subunit protein.
Length = 359
Score = 470 bits (1158), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFLPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>D90086-1|BAA14123.1| 359|Homo sapiens pyruvate dehydrogenase beta
subunit protein.
Length = 359
Score = 470 bits (1158), Expect = e-132
Identities = 215/314 (68%), Positives = 258/314 (82%), Gaps = 1/314 (0%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTP 74
A A+ VTVRDA+NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV+RGLWKKYGDKR+IDTP
Sbjct: 27 APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTP 86
Query: 75 ITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRG 134
I+E L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRG
Sbjct: 87 ISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRG 146
Query: 135 PNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMY 194
PNGA++GVAAQHSQCF AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MY
Sbjct: 147 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMY 206
Query: 195 GIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEV 254
G+PF EAQSKDF++PIGKAK+ER+G HIT+V R L+AA L+ +G+ECEV
Sbjct: 207 GVPFEFLPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLS-KEGVECEV 265
Query: 255 VNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
+N+RTIRPMD +TI S+ KT+HL+TVE GWPQ G+GAEICAR+ME P+F LDAP RV
Sbjct: 266 INMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRV 325
Query: 315 CGADVPMPYARTLE 328
GADVPMPYA+ LE
Sbjct: 326 TGADVPMPYAKILE 339
>AB209241-1|BAD92478.1| 164|Homo sapiens Hypothetical protein
DKFZp564K0164 variant protein.
Length = 164
Score = 229 bits (561), Expect = 8e-60
Identities = 99/132 (75%), Positives = 120/132 (90%)
Query: 92 LKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPVPIVFRGPNGAASGVAAQHSQCFG 151
L+PICEFMTFNFSMQAID +INSAAKT+YMS G PVPIVFRGPNGA++GVAAQHSQCF
Sbjct: 24 LRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFA 83
Query: 152 AWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEAQSKDFVL 211
AWY HCPGLKV+ P+++EDAKGL+K+AIRD +PVV+LE+E+MYG+PF EAQSKDF++
Sbjct: 84 AWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLI 143
Query: 212 PIGKAKVEREGR 223
PIGKAK+ER+G+
Sbjct: 144 PIGKAKIERQGK 155
>U50708-1|AAB16763.1| 392|Homo sapiens branched chain
alpha-ketoacid dehydrogenase E1 beta subunit protein.
Length = 392
Score = 180 bits (439), Expect = 5e-45
Identities = 101/299 (33%), Positives = 151/299 (50%), Gaps = 6/299 (2%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEA 204
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y ++E
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA---AEEV 251
Query: 205 QSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMD 264
+ + +P+ +A+V +EG +TLV G + A G+ CEV++LRTI P D
Sbjct: 252 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWD 311
Query: 265 FDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 323
DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 312 VDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>M55575-1|AAA51812.1| 392|Homo sapiens branched chain alpha-keto
acid dehydrogenase E1-beta subunit protein.
Length = 392
Score = 180 bits (439), Expect = 5e-45
Identities = 101/299 (33%), Positives = 151/299 (50%), Gaps = 6/299 (2%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEA 204
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y ++E
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA---AEEV 251
Query: 205 QSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMD 264
+ + +P+ +A+V +EG +TLV G + A G+ CEV++LRTI P D
Sbjct: 252 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWD 311
Query: 265 FDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 323
DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 312 VDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>D90391-1|BAA14389.1| 392|Homo sapiens E-1-beta subunit of branched
chain alpha-keto acid dehydrogenase protein.
Length = 392
Score = 180 bits (439), Expect = 5e-45
Identities = 101/299 (33%), Positives = 151/299 (50%), Gaps = 6/299 (2%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEA 204
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y ++E
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA---AEEV 251
Query: 205 QSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMD 264
+ + +P+ +A+V +EG +TLV G + A G+ CEV++LRTI P D
Sbjct: 252 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWD 311
Query: 265 FDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 323
DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 312 VDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>BT020063-1|AAV38866.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 180 bits (439), Expect = 5e-45
Identities = 101/299 (33%), Positives = 151/299 (50%), Gaps = 6/299 (2%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEA 204
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y ++E
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA---AEEV 251
Query: 205 QSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMD 264
+ + +P+ +A+V +EG +TLV G + A G+ CEV++LRTI P D
Sbjct: 252 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWD 311
Query: 265 FDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 323
DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 312 VDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>BC040139-1|AAH40139.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 180 bits (439), Expect = 5e-45
Identities = 101/299 (33%), Positives = 151/299 (50%), Gaps = 6/299 (2%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEA 204
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y ++E
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA---AEEV 251
Query: 205 QSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMD 264
+ + +P+ +A+V +EG +TLV G + A G+ CEV++LRTI P D
Sbjct: 252 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWD 311
Query: 265 FDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 323
DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 312 VDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>AL391595-1|CAI15049.1| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 180 bits (439), Expect = 5e-45
Identities = 101/299 (33%), Positives = 151/299 (50%), Gaps = 6/299 (2%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEA 204
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y ++E
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA---AEEV 251
Query: 205 QSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMD 264
+ + +P+ +A+V +EG +TLV G + A G+ CEV++LRTI P D
Sbjct: 252 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWD 311
Query: 265 FDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 323
DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 312 VDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>AL049696-1|CAC36881.2| 392|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 392
Score = 180 bits (439), Expect = 5e-45
Identities = 101/299 (33%), Positives = 151/299 (50%), Gaps = 6/299 (2%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEA 204
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y ++E
Sbjct: 195 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA---AEEV 251
Query: 205 QSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMD 264
+ + +P+ +A+V +EG +TLV G + A G+ CEV++LRTI P D
Sbjct: 252 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWD 311
Query: 265 FDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 323
DTI +S+ KT L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 312 VDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 369
>X52446-1|CAA36685.1| 373|Homo sapiens protein ( Human mRNA for
E1b-beta subunit of the branched-chain complex. ).
Length = 373
Score = 179 bits (435), Expect = 2e-44
Identities = 100/299 (33%), Positives = 151/299 (50%), Gaps = 6/299 (2%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 57 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 115
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 116 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 175
Query: 145 QHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEA 204
HSQ A+++HCPG+KV++P S AKGLL + I D +P + E +I+Y ++E
Sbjct: 176 YHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEPKILYRAA---AEEV 232
Query: 205 QSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMD 264
+ + +P+ +A+V +EG +TLV G + A G+ CEV++LRTI P D
Sbjct: 233 PIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCEVIDLRTIIPWD 292
Query: 265 FDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGADVPMPY 323
DTI +S+ K+ L+ + G +EI + V E F L+AP+ RVCG D P P+
Sbjct: 293 VDTICKSVIKSGRLLISHEAPLTGGFASEISSTVQEE-CFLNLEAPISRVCGYDTPFPH 350
>BC034481-1|AAH34481.1| 218|Homo sapiens BCKDHB protein protein.
Length = 218
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/138 (31%), Positives = 64/138 (46%), Gaps = 2/138 (1%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKV 162
HSQ A+++HCPG+K+
Sbjct: 195 YHSQSPEAFFAHCPGIKI 212
>AL391595-2|CAI15050.1| 218|Homo sapiens branched chain keto acid
dehydrogenase E1, beta polypeptide (maple syrup urine
protein.
Length = 218
Score = 77.8 bits (183), Expect = 5e-14
Identities = 43/138 (31%), Positives = 64/138 (46%), Gaps = 2/138 (1%)
Query: 26 ALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEXXXXXXXX 85
++ A+D + +D + GE+VA + G ++ T GL KYG RV +TP+ E
Sbjct: 76 SVTSALDNSLAKDPTAVIFGEDVA-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGI 134
Query: 86 XXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNGAASGVAA 144
I E ++ A D I+N AAK Y S + R P G A
Sbjct: 135 GIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGAL 194
Query: 145 QHSQCFGAWYSHCPGLKV 162
HSQ A+++HCPG+K+
Sbjct: 195 YHSQSPEAFFAHCPGIKI 212
>M19123-1|AAA60052.1| 56|Homo sapiens PDHB protein.
Length = 56
Score = 71.7 bits (168), Expect = 4e-12
Identities = 33/43 (76%), Positives = 38/43 (88%)
Query: 15 ALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKV 57
A A+ VTVRD +NQ +DEE+ERDEKVF+LGEEVAQYDGAYKV
Sbjct: 5 APAALQVTVRDGINQGMDEELERDEKVFLLGEEVAQYDGAYKV 47
>Z49258-4|CAH69900.1| 540|Homo sapiens transketolase-like 1
protein.
Length = 540
Score = 59.3 bits (137), Expect = 2e-08
Identities = 38/93 (40%), Positives = 53/93 (56%), Gaps = 4/93 (4%)
Query: 213 IGKAKVERE--GRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 270
IG+AKV R +T++ AG AL AA++L+ + I V++L TI+P+D TI
Sbjct: 407 IGQAKVLRHCVSDKVTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVS 465
Query: 271 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
S T +ITVE +PQ GIG +CA V P
Sbjct: 466 SAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 498
>Z49258-1|CAH69899.1| 596|Homo sapiens transketolase-like 1
protein.
Length = 596
Score = 59.3 bits (137), Expect = 2e-08
Identities = 38/93 (40%), Positives = 53/93 (56%), Gaps = 4/93 (4%)
Query: 213 IGKAKVERE--GRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 270
IG+AKV R +T++ AG AL AA++L+ + I V++L TI+P+D TI
Sbjct: 463 IGQAKVLRHCVSDKVTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVS 521
Query: 271 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
S T +ITVE +PQ GIG +CA V P
Sbjct: 522 SAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 554
>BC025382-1|AAH25382.2| 596|Homo sapiens transketolase-like 1
protein.
Length = 596
Score = 59.3 bits (137), Expect = 2e-08
Identities = 38/93 (40%), Positives = 53/93 (56%), Gaps = 4/93 (4%)
Query: 213 IGKAKVERE--GRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 270
IG+AKV R +T++ AG AL AA++L+ + I V++L TI+P+D TI
Sbjct: 463 IGQAKVLRHCVSDKVTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVS 521
Query: 271 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
S T +ITVE +PQ GIG +CA V P
Sbjct: 522 SAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 554
>CR533560-1|CAG38591.1| 626|Homo sapiens DKFZP434L1717 protein.
Length = 626
Score = 58.0 bits (134), Expect = 5e-08
Identities = 37/93 (39%), Positives = 54/93 (58%), Gaps = 4/93 (4%)
Query: 213 IGKAKVEREGRH--ITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 270
IG+AKV R G + +T++ AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 271 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>BC125101-1|AAI25102.1| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 58.0 bits (134), Expect = 5e-08
Identities = 37/93 (39%), Positives = 54/93 (58%), Gaps = 4/93 (4%)
Query: 213 IGKAKVEREGRH--ITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 270
IG+AKV R G + +T++ AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 271 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>BC028707-1|AAH28707.4| 626|Homo sapiens transketolase-like 2
protein.
Length = 626
Score = 58.0 bits (134), Expect = 5e-08
Identities = 37/93 (39%), Positives = 54/93 (58%), Gaps = 4/93 (4%)
Query: 213 IGKAKVEREGRH--ITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 270
IG+AKV R G + +T++ AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 271 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>AK057537-1|BAB71524.1| 320|Homo sapiens protein ( Homo sapiens
cDNA FLJ32975 fis, clone TESTI2013832, moderately
similar to Xenopus laevis transketolase mRNA. ).
Length = 320
Score = 58.0 bits (134), Expect = 5e-08
Identities = 37/93 (39%), Positives = 54/93 (58%), Gaps = 4/93 (4%)
Query: 213 IGKAKVEREGRH--ITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 270
IG+AKV R G + +T++ AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 187 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 245
Query: 271 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
S T +ITVE + + GIG +CA V P
Sbjct: 246 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 278
>AK057325-1|BAB71427.1| 626|Homo sapiens protein ( Homo sapiens
cDNA FLJ32763 fis, clone TESTI2001827, moderately
similar to TRANSKETOLASE (EC 2.2.1.1). ).
Length = 626
Score = 58.0 bits (134), Expect = 5e-08
Identities = 37/93 (39%), Positives = 54/93 (58%), Gaps = 4/93 (4%)
Query: 213 IGKAKVEREGRH--ITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIAR 270
IG+AKV R G + +T++ AG AL+AA+ L+ +GI V++ TI+P+D TI
Sbjct: 493 IGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLS-QQGISVRVIDPFTIKPLDAATIIS 551
Query: 271 SIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
S T +ITVE + + GIG +CA V P
Sbjct: 552 SAKATGGRVITVEDHYREGGIGEAVCAAVSREP 584
>X91817-1|CAA62925.1| 557|Homo sapiens transketolase protein.
Length = 557
Score = 56.0 bits (129), Expect = 2e-07
Identities = 43/138 (31%), Positives = 65/138 (47%), Gaps = 4/138 (2%)
Query: 168 AEDAKGLLKAAIRDPDPVVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVERE--GRHI 225
A +AKG+ P+ +V+ + + I + I KV R +
Sbjct: 379 AANAKGMCFIRTTRPETMVIYTPQERFEIGQAKGVSMLQDSWSSVISYQKVLRHCVSDKV 438
Query: 226 TLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQG 284
T++ AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 439 TVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 497
Query: 285 WPQSGIGAEICARVMESP 302
+PQ GIG +CA V P
Sbjct: 498 YPQGGIGEAVCAAVSMDP 515
>Z49258-5|CAI39236.1| 146|Homo sapiens transketolase-like 1
protein.
Length = 146
Score = 55.2 bits (127), Expect = 3e-07
Identities = 32/79 (40%), Positives = 46/79 (58%), Gaps = 2/79 (2%)
Query: 225 ITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVEQ 283
+T++ AG AL AA++L+ + I V++L TI+P+D TI S T +ITVE
Sbjct: 27 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVED 85
Query: 284 GWPQSGIGAEICARVMESP 302
+PQ GIG +CA V P
Sbjct: 86 HYPQGGIGEAVCAAVSMDP 104
>X67688-1|CAA47919.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 206 SKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 265
++DF + K ++ + +T++ AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 266 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>U55017-1|AAA98961.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 206 SKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 265
++DF + K ++ + +T++ AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 266 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>BC024026-1|AAH24026.2| 536|Homo sapiens TKT protein protein.
Length = 536
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 206 SKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 265
++DF + K ++ + +T++ AG AL AAE L K I V++ TI+P+D
Sbjct: 397 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 455
Query: 266 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 456 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 505
>BC009970-1|AAH09970.1| 623|Homo sapiens transketolase
(Wernicke-Korsakoff syndrome) protein.
Length = 623
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 206 SKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 265
++DF + K ++ + +T++ AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 266 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>BC008615-1|AAH08615.1| 395|Homo sapiens Similar to transketolase
(Wernicke-Korsakoff syndrome) protein.
Length = 395
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 206 SKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 265
++DF + K ++ + +T++ AG AL AAE L K I V++ TI+P+D
Sbjct: 256 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 314
Query: 266 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 315 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 364
>BC002433-1|AAH02433.1| 457|Homo sapiens TKT protein protein.
Length = 457
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 206 SKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 265
++DF + K ++ + +T++ AG AL AAE L K I V++ TI+P+D
Sbjct: 318 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 376
Query: 266 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 377 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 426
>AK223614-1|BAD97334.1| 623|Homo sapiens transketolase variant
protein.
Length = 623
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 2/110 (1%)
Query: 206 SKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 265
++DF + K ++ + +T++ AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 266 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRV 314
I S T ++TVE + + GIG + + V+ P V RV
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRV 592
>L12711-1|AAA61222.1| 623|Homo sapiens transketolase protein.
Length = 623
Score = 42.7 bits (96), Expect = 0.002
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 2/98 (2%)
Query: 206 SKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDF 265
++DF + K ++ + +T++ AG AL AAE L K I V++ TI+P+D
Sbjct: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEK-INIRVLDPFTIKPLDR 542
Query: 266 DTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESP 302
I S T ++TVE + + GIG + + V+ P
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEP 580
>D84361-2|BAA12323.1| 474|Homo sapiens p52 isoform of N-Shc
protein.
Length = 474
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 179 IRDPDPVVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDT-- 236
+R PD ++ + M I F + + D+V + K V R HI C G D
Sbjct: 116 LRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIG 175
Query: 237 ALKAAEQLAGSKGIEC 252
++ A +L + ++C
Sbjct: 176 SIGQAFELRFKQYLQC 191
>D84361-1|BAA12322.1| 594|Homo sapiens p64 isoform of N-Shc
protein.
Length = 594
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 179 IRDPDPVVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDT-- 236
+R PD ++ + M I F + + D+V + K V R HI C G D
Sbjct: 236 LRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIG 295
Query: 237 ALKAAEQLAGSKGIEC 252
++ A +L + ++C
Sbjct: 296 SIGQAFELRFKQYLQC 311
>AL353150-2|CAI16865.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 179 IRDPDPVVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDT-- 236
+R PD ++ + M I F + + D+V + K V R HI C G D
Sbjct: 236 LRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIG 295
Query: 237 ALKAAEQLAGSKGIEC 252
++ A +L + ++C
Sbjct: 296 SIGQAFELRFKQYLQC 311
>AL160054-4|CAI41366.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 31.5 bits (68), Expect = 4.6
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 179 IRDPDPVVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDT-- 236
+R PD ++ + M I F + + D+V + K V R HI C G D
Sbjct: 236 LRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIG 295
Query: 237 ALKAAEQLAGSKGIEC 252
++ A +L + ++C
Sbjct: 296 SIGQAFELRFKQYLQC 311
>U51015-1|AAB09779.1| 46|Homo sapiens branched chain
alpha-ketoacid dehydrogenase E1-beta subunit protein.
Length = 46
Score = 31.1 bits (67), Expect = 6.1
Identities = 11/20 (55%), Positives = 14/20 (70%)
Query: 304 FFELDAPVWRVCGADVPMPY 323
F L+AP+ RVCG D P P+
Sbjct: 4 FLNLEAPISRVCGYDTPFPH 23
>U14622-1|AAA21557.1| 63|Homo sapiens protein ( Human
transketolase-like protein gene, partial cds. ).
Length = 63
Score = 31.1 bits (67), Expect = 6.1
Identities = 21/59 (35%), Positives = 34/59 (57%), Gaps = 2/59 (3%)
Query: 225 ITLVCAGRGTDTALKAAEQLAGSKGIECEVVNLRTIRPMDFDTIARSIAKTH-HLITVE 282
+T++ AG AL AA++L+ + I V++L TI+P+D T S T +I+VE
Sbjct: 3 VTVIGAGITVYEALAAADELS-KQDIFIRVIDLFTIKPLDVATNVSSAKATEGRIISVE 60
>BC026314-1|AAH26314.1| 594|Homo sapiens SHC (Src homology 2 domain
containing) transforming protein 3 protein.
Length = 594
Score = 30.7 bits (66), Expect = 8.0
Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 2/76 (2%)
Query: 179 IRDPDPVVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDT-- 236
+R PD ++ + M I F + + D+V + K V R HI C G D
Sbjct: 236 LRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVTKDPVNRRACHILECCDGLAQDVIG 295
Query: 237 ALKAAEQLAGSKGIEC 252
++ A +L + ++C
Sbjct: 296 SIGQAFELRFKQYLQC 311
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.320 0.135 0.404
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 45,876,581
Number of Sequences: 224733
Number of extensions: 1896167
Number of successful extensions: 4296
Number of sequences better than 10.0: 47
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4200
Number of HSP's gapped (non-prelim): 47
length of query: 351
length of database: 73,234,838
effective HSP length: 91
effective length of query: 260
effective length of database: 52,784,135
effective search space: 13723875100
effective search space used: 13723875100
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 66 (30.7 bits)
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