Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA002750-TA|BGIBMGA002750-PA|IPR005475|Transketolase,
central region, IPR005476|Transketolase, C-terminal,
IPR009014|Transketolase, C-terminal-like
(351 letters)
Database: fruitfly
52,641 sequences; 24,830,863 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BT001756-1|AAN71511.1| 365|Drosophila melanogaster RH05604p pro... 499 e-141
AY047573-1|AAK77305.1| 365|Drosophila melanogaster GH08474p pro... 499 e-141
AE014297-4317|AAF56855.2| 365|Drosophila melanogaster CG11876-P... 499 e-141
AE014297-4316|AAN14149.1| 365|Drosophila melanogaster CG11876-P... 499 e-141
AY071212-1|AAL48834.1| 364|Drosophila melanogaster RE25729p pro... 171 2e-42
BT024274-1|ABC86336.1| 273|Drosophila melanogaster IP14839p pro... 158 9e-39
AE014297-4319|AAN14151.1| 273|Drosophila melanogaster CG11876-P... 158 9e-39
AE014297-4318|AAN14150.1| 273|Drosophila melanogaster CG11876-P... 158 9e-39
AY113331-1|AAM29336.1| 623|Drosophila melanogaster AT29350p pro... 36 0.084
AE014296-3011|AAF49267.1| 623|Drosophila melanogaster CG5103-PA... 36 0.084
AE014297-4087|AAF56679.2| 404|Drosophila melanogaster CG31063-P... 31 3.1
BT021436-1|AAX33584.1| 984|Drosophila melanogaster GH14495p pro... 29 9.6
AE014296-1479|AAF50397.2| 1653|Drosophila melanogaster CG32352-P... 29 9.6
AE014296-1478|AAF50396.2| 1709|Drosophila melanogaster CG32352-P... 29 9.6
>BT001756-1|AAN71511.1| 365|Drosophila melanogaster RH05604p
protein.
Length = 365
Score = 499 bits (1231), Expect = e-141
Identities = 233/345 (67%), Positives = 273/345 (79%), Gaps = 2/345 (0%)
Query: 6 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 64
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 65 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAG 124
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDHIINSAAKTFYMSAG
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAG 132
Query: 125 TVPVPIVFRGPNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDP 184
V VPIVFRGPNGAASGVAAQHSQCF AWY+HCPGLKVL PY AEDA+GLLK+AIRDPDP
Sbjct: 133 AVNVPIVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDP 192
Query: 185 VVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQL 244
VV LE+E++YG FP++D KDF++PIGKAKV R G+ ITLV + +T+L AA +L
Sbjct: 193 VVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAEL 252
Query: 245 AGSKGIECEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSF 304
A KGIE EV+NLR+IRP+D TI S+ KTHHL+TVE GWPQ G+GAEICAR+ME +F
Sbjct: 253 A-KKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTF 311
Query: 305 FELDAPVWRVCGADVPMPYARTLEXXXXXXXXXXXXXXTNVLGNK 349
FELDAPVWR G DVPMPYA+TLE VLG K
Sbjct: 312 FELDAPVWRCAGVDVPMPYAKTLEAHALPRAQDLVEATLKVLGGK 356
>AY047573-1|AAK77305.1| 365|Drosophila melanogaster GH08474p
protein.
Length = 365
Score = 499 bits (1230), Expect = e-141
Identities = 233/345 (67%), Positives = 273/345 (79%), Gaps = 2/345 (0%)
Query: 6 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 64
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 65 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAG 124
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDHIINSAAKTFYMSAG
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAG 132
Query: 125 TVPVPIVFRGPNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDP 184
V VPIVFRGPNGAASGVAAQHSQCF AWY+HCPGLKVL PY AEDA+GLLK+AIRDPDP
Sbjct: 133 AVNVPIVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDP 192
Query: 185 VVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQL 244
VV LE+E++YG FP++D KDF++PIGKAKV R G+ ITLV + +T+L AA +L
Sbjct: 193 VVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAEL 252
Query: 245 AGSKGIECEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSF 304
A KGIE EV+NLR+IRP+D TI S+ KTHHL+TVE GWPQ G+GAEICAR+ME +F
Sbjct: 253 A-KKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTF 311
Query: 305 FELDAPVWRVCGADVPMPYARTLEXXXXXXXXXXXXXXTNVLGNK 349
FELDAPVWR G DVPMPYA+TLE VLG K
Sbjct: 312 FELDAPVWRCAGVDVPMPYAKTLEAHALPRVQDLVEATLKVLGGK 356
>AE014297-4317|AAF56855.2| 365|Drosophila melanogaster CG11876-PD,
isoform D protein.
Length = 365
Score = 499 bits (1230), Expect = e-141
Identities = 233/345 (67%), Positives = 273/345 (79%), Gaps = 2/345 (0%)
Query: 6 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 64
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 65 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAG 124
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDHIINSAAKTFYMSAG
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAG 132
Query: 125 TVPVPIVFRGPNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDP 184
V VPIVFRGPNGAASGVAAQHSQCF AWY+HCPGLKVL PY AEDA+GLLK+AIRDPDP
Sbjct: 133 AVNVPIVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDP 192
Query: 185 VVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQL 244
VV LE+E++YG FP++D KDF++PIGKAKV R G+ ITLV + +T+L AA +L
Sbjct: 193 VVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAEL 252
Query: 245 AGSKGIECEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSF 304
A KGIE EV+NLR+IRP+D TI S+ KTHHL+TVE GWPQ G+GAEICAR+ME +F
Sbjct: 253 A-KKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTF 311
Query: 305 FELDAPVWRVCGADVPMPYARTLEXXXXXXXXXXXXXXTNVLGNK 349
FELDAPVWR G DVPMPYA+TLE VLG K
Sbjct: 312 FELDAPVWRCAGVDVPMPYAKTLEAHALPRVQDLVEATLKVLGGK 356
>AE014297-4316|AAN14149.1| 365|Drosophila melanogaster CG11876-PA,
isoform A protein.
Length = 365
Score = 499 bits (1230), Expect = e-141
Identities = 233/345 (67%), Positives = 273/345 (79%), Gaps = 2/345 (0%)
Query: 6 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 64
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 65 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAG 124
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDHIINSAAKTFYMSAG
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMSAG 132
Query: 125 TVPVPIVFRGPNGAASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDP 184
V VPIVFRGPNGAASGVAAQHSQCF AWY+HCPGLKVL PY AEDA+GLLK+AIRDPDP
Sbjct: 133 AVNVPIVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDP 192
Query: 185 VVMLEDEIMYGIPFPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQL 244
VV LE+E++YG FP++D KDF++PIGKAKV R G+ ITLV + +T+L AA +L
Sbjct: 193 VVFLENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAEL 252
Query: 245 AGSKGIECEVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSF 304
A KGIE EV+NLR+IRP+D TI S+ KTHHL+TVE GWPQ G+GAEICAR+ME +F
Sbjct: 253 A-KKGIEAEVINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTF 311
Query: 305 FELDAPVWRVCGADVPMPYARTLEXXXXXXXXXXXXXXTNVLGNK 349
FELDAPVWR G DVPMPYA+TLE VLG K
Sbjct: 312 FELDAPVWRCAGVDVPMPYAKTLEAHALPRVQDLVEATLKVLGGK 356
>AY071212-1|AAL48834.1| 364|Drosophila melanogaster RE25729p
protein.
Length = 364
Score = 171 bits (415), Expect = 2e-42
Identities = 98/306 (32%), Positives = 156/306 (50%), Gaps = 6/306 (1%)
Query: 19 KPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKKYGDKRVIDTPITEX 78
K + + +A+N A+D ++ ++ + GE+V + G ++ + L KYG +RV +TP+ E
Sbjct: 41 KRMNMFNAINNAMDLALDENKSALLFGEDVG-FGGVFRCSVNLRNKYGSQRVFNTPLCEQ 99
Query: 79 XXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHIINSAAKTFYMSAGTVPV-PIVFRGPNG 137
I E ++ + D I+N AAK Y S G + FR P G
Sbjct: 100 GIAGFAIGVANTGATAIAEIQFADYIFPSFDQIVNEAAKYRYRSGGLFDCGSLTFRVPCG 159
Query: 138 AASGVAAQHSQCFGAWYSHCPGLKVLMPYSAEDAKGLLKAAIRDPDPVVMLEDEIMYGIP 197
A A HSQ A+++H PGL+V++P AKGL+ A IRDP+P ++ E + +Y
Sbjct: 160 AVGHGALYHSQSPEAYFAHTPGLRVVVPRGPIKAKGLILACIRDPNPCIVFEPKTLYRAA 219
Query: 198 FPMSDEAQSKDFVLPIGKAKVEREGRHITLVCAGRGTDTALKAAEQLAGSKGIECEVVNL 257
+E ++ + +GKA + R G+ +TL+ G L+ AE + I+CEV++L
Sbjct: 220 V---EEVPAEYYTSQLGKADILRHGKDVTLIGWGTQVHVLLEVAEIAKSTLNIDCEVIDL 276
Query: 258 RTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVMESPSFFELDAPVWRVCGA 317
+I P D TI S KT +I + G G+E+ + + E F L+APV RV G
Sbjct: 277 VSILPWDAITICTSAKKTGRVIIAHEAPLTQGFGSELASYIQEK-CFLHLEAPVKRVAGW 335
Query: 318 DVPMPY 323
D P P+
Sbjct: 336 DTPFPH 341
>BT024274-1|ABC86336.1| 273|Drosophila melanogaster IP14839p
protein.
Length = 273
Score = 158 bits (384), Expect = 9e-39
Identities = 79/127 (62%), Positives = 96/127 (75%), Gaps = 5/127 (3%)
Query: 6 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 64
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 65 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHI-INSAAKTFYMSA 123
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDH I AK
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHAKILDCAKP---PV 129
Query: 124 GTVPVPI 130
G P+PI
Sbjct: 130 GDRPLPI 136
>AE014297-4319|AAN14151.1| 273|Drosophila melanogaster CG11876-PC,
isoform C protein.
Length = 273
Score = 158 bits (384), Expect = 9e-39
Identities = 79/127 (62%), Positives = 96/127 (75%), Gaps = 5/127 (3%)
Query: 6 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 64
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 65 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHI-INSAAKTFYMSA 123
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDH I AK
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHAKILDCAKP---PV 129
Query: 124 GTVPVPI 130
G P+PI
Sbjct: 130 GDRPLPI 136
>AE014297-4318|AAN14150.1| 273|Drosophila melanogaster CG11876-PB,
isoform B protein.
Length = 273
Score = 158 bits (384), Expect = 9e-39
Identities = 79/127 (62%), Positives = 96/127 (75%), Gaps = 5/127 (3%)
Query: 6 SRRSFATS-KALASKPVTVRDALNQAIDEEMERDEKVFVLGEEVAQYDGAYKVTRGLWKK 64
++R+F+TS KALA+K +TVRDALN A+D+E+ RD++VF+LGEEVAQYDGAYKV+RGLWKK
Sbjct: 13 AQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKVSRGLWKK 72
Query: 65 YGDKRVIDTPITEXXXXXXXXXXXXXXLKPICEFMTFNFSMQAIDHI-INSAAKTFYMSA 123
YGDKRVIDTPITE L+P+CEFMT+NFSMQAIDH I AK
Sbjct: 73 YGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHAKILDCAKP---PV 129
Query: 124 GTVPVPI 130
G P+PI
Sbjct: 130 GDRPLPI 136
>AY113331-1|AAM29336.1| 623|Drosophila melanogaster AT29350p
protein.
Length = 623
Score = 35.9 bits (79), Expect = 0.084
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Query: 198 FPMSDEAQSKDFVLPIGKAKVERE--GRHITLVCAGRGTDTALKAAEQLAGSKGIECEVV 255
+P + + D V +G KV R+ + L+ AG L AAE+L I V+
Sbjct: 475 YPSTTVIYNNDEVFAVGLGKVVRQKPSDEVLLIGAGVTLYECLAAAERLE-EDCITARVI 533
Query: 256 NLRTIRPMDFDTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSF 304
+ T++P+D I + ++ VE + Q G+G + + + + +F
Sbjct: 534 DPFTVKPLDVGLIVKHGKLCRGRIVVVEDHYQQGGLGEAVLSALADYRNF 583
>AE014296-3011|AAF49267.1| 623|Drosophila melanogaster CG5103-PA
protein.
Length = 623
Score = 35.9 bits (79), Expect = 0.084
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 4/110 (3%)
Query: 198 FPMSDEAQSKDFVLPIGKAKVERE--GRHITLVCAGRGTDTALKAAEQLAGSKGIECEVV 255
+P + + D V +G KV R+ + L+ AG L AAE+L I V+
Sbjct: 475 YPSTTVIYNNDEVFAVGLGKVVRQKPSDEVLLIGAGVTLYECLAAAERLE-EDCITARVI 533
Query: 256 NLRTIRPMDFDTIARSIAKTH-HLITVEQGWPQSGIGAEICARVMESPSF 304
+ T++P+D I + ++ VE + Q G+G + + + + +F
Sbjct: 534 DPFTVKPLDVGLIVKHGKLCRGRIVVVEDHYQQGGLGEAVLSALADYRNF 583
>AE014297-4087|AAF56679.2| 404|Drosophila melanogaster CG31063-PA
protein.
Length = 404
Score = 30.7 bits (66), Expect = 3.1
Identities = 20/71 (28%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
Query: 253 EVVNLRTIRPMDFDTIARSIAKTHHLITVEQGWPQSGIGAEICARVME-SPSFFEL-DAP 310
++V +R RP + I S T + +++ P G+ E+CA +++ + S+ E+
Sbjct: 247 KLVLVRQFRPAVYHGIISSAKGTFDEVDLKEFPPAIGVTLELCAGIVDKNKSWVEIAREE 306
Query: 311 VWRVCGADVPM 321
V CG DVP+
Sbjct: 307 VVEECGYDVPV 317
>BT021436-1|AAX33584.1| 984|Drosophila melanogaster GH14495p
protein.
Length = 984
Score = 29.1 bits (62), Expect = 9.6
Identities = 12/31 (38%), Positives = 18/31 (58%)
Query: 159 GLKVLMPYSAEDAKGLLKAAIRDPDPVVMLE 189
G++ L P+ E +G KA D DPV+ +E
Sbjct: 156 GIRELTPFEQELQRGTSKAGTNDTDPVIEVE 186
>AE014296-1479|AAF50397.2| 1653|Drosophila melanogaster CG32352-PA,
isoform A protein.
Length = 1653
Score = 29.1 bits (62), Expect = 9.6
Identities = 12/31 (38%), Positives = 18/31 (58%)
Query: 159 GLKVLMPYSAEDAKGLLKAAIRDPDPVVMLE 189
G++ L P+ E +G KA D DPV+ +E
Sbjct: 100 GIRELTPFEQELQRGTSKAGTNDTDPVIEVE 130
>AE014296-1478|AAF50396.2| 1709|Drosophila melanogaster CG32352-PB,
isoform B protein.
Length = 1709
Score = 29.1 bits (62), Expect = 9.6
Identities = 12/31 (38%), Positives = 18/31 (58%)
Query: 159 GLKVLMPYSAEDAKGLLKAAIRDPDPVVMLE 189
G++ L P+ E +G KA D DPV+ +E
Sbjct: 156 GIRELTPFEQELQRGTSKAGTNDTDPVIEVE 186
Database: fruitfly
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 24,830,863
Number of sequences in database: 52,641
Lambda K H
0.320 0.135 0.404
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 15,131,507
Number of Sequences: 52641
Number of extensions: 610422
Number of successful extensions: 1337
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1318
Number of HSP's gapped (non-prelim): 14
length of query: 351
length of database: 24,830,863
effective HSP length: 86
effective length of query: 265
effective length of database: 20,303,737
effective search space: 5380490305
effective search space used: 5380490305
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 62 (29.1 bits)
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